-- dump date 20140619_091050 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 585056000001 SEQ_END SEQ_END NC_011739.1 33809 33809 DR NC_011739.1; contig end 33809..33809 Escherichia coli UMN026 585056000002 SEQ_END SEQ_END NC_011749.1 122301 122301 DR NC_011749.1; contig end 122301..122301 Escherichia coli UMN026 585056000003 SEQ_END SEQ_END NC_011751.1 5202090 5202090 DR NC_011751.1; contig end 5202090..5202090 Escherichia coli UMN026 YP_002381183.1 CDS p2ECUMN_0001 NC_011739.1 250 1251 D PI protein (Replication initiation protein) 250..1251 Escherichia coli UMN026 7169423 YP_002381184.1 CDS p2ECUMN_0002 NC_011739.1 1260 1703 D Evidence 5 : No homology to any previously reported sequences; Hypothetical protein; putative membrane protein 1260..1703 Escherichia coli UMN026 7169448 YP_002381185.1 CDS p2ECUMN_0003 NC_011739.1 1722 2186 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1722..2186 Escherichia coli UMN026 7169461 YP_002381186.1 CDS p2ECUMN_0004 NC_011739.1 2569 2784 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative membrane protein complement(2569..2784) Escherichia coli UMN026 7169459 YP_002381187.1 CDS p2ECUMN_0005 NC_011739.1 2935 3216 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein; putative membrane protein complement(2935..3216) Escherichia coli UMN026 7169457 YP_002381188.1 CDS p2ECUMN_0006 NC_011739.1 3378 3662 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative membrane protein complement(3378..3662) Escherichia coli UMN026 7169449 YP_002381189.1 CDS p2ECUMN_0007 NC_011739.1 3699 4046 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative Methionine repressor-like protein complement(3699..4046) Escherichia coli UMN026 7169467 YP_002381190.1 CDS p2ECUMN_0008 NC_011739.1 4095 4757 R putative YafB protein complement(4095..4757) Escherichia coli UMN026 7169450 YP_002381191.1 CDS p2ECUMN_0009 NC_011739.1 4869 5759 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase (Protein D) complement(4869..5759) Escherichia coli UMN026 7169458 YP_002381192.1 CDS p2ECUMN_0010 NC_011739.1 6240 6896 R Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein; putative exported protein complement(6240..6896) Escherichia coli UMN026 7169447 YP_002381193.1 CDS hns NC_011739.1 7000 7464 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; global nucleic acid-binding transcriptional dual regulator complement(7000..7464) Escherichia coli UMN026 7169465 YP_002381194.1 CDS p2ECUMN_0012 NC_011739.1 7482 7688 R Evidence 4 : Homologs of previously reported genes of unknown function; Conserved hypothetical protein, putative haemolysin expression modulating protein complement(7482..7688) Escherichia coli UMN026 7169470 YP_002381195.1 CDS p2ECUMN_0013 NC_011739.1 7685 9838 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA topoisomerase III complement(7685..9838) Escherichia coli UMN026 7169464 YP_002381196.1 CDS p2ECUMN_0014 NC_011739.1 9850 10467 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(9850..10467) Escherichia coli UMN026 7169451 YP_002381197.1 CDS p2ECUMN_0015 NC_011739.1 10464 10784 R Evidence 6 : Doubtful CDS; hypothetical protein complement(10464..10784) Escherichia coli UMN026 7169460 YP_002381198.1 CDS p2ECUMN_0016 NC_011739.1 10844 11248 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(10844..11248) Escherichia coli UMN026 7169463 YP_002381199.1 CDS p2ECUMN_0017 NC_011739.1 11264 11779 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative endonuclease precursor complement(11264..11779) Escherichia coli UMN026 7169452 YP_002381200.1 CDS p2ECUMN_0018 NC_011739.1 11776 12210 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein; putative exported protein, putative membrane protein complement(11776..12210) Escherichia coli UMN026 7169462 YP_002381201.1 CDS p2ECUMN_0019 NC_011739.1 12292 12549 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(12292..12549) Escherichia coli UMN026 7169453 YP_002381202.1 CDS p2ECUMN_0020 NC_011739.1 12555 12857 R Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein, putative plasmid conjugation protein kikA, putative exported protein complement(12555..12857) Escherichia coli UMN026 7169454 YP_002381203.1 CDS p2ECUMN_0021 NC_011739.1 12854 13267 R Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein; putative exported protein, putative VirB/Tra/Trw family protein complement(12854..13267) Escherichia coli UMN026 7169455 YP_002381204.1 CDS p2ECUMN_0022 NC_011739.1 13264 15105 R Evidence 5 : No homology to any previously reported sequences; Hypothetical protein, putative TraG/TraD family protein, putative membrane protein complement(13264..15105) Escherichia coli UMN026 7169456 YP_002381205.1 CDS p2ECUMN_0023 NC_011739.1 15102 16133 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative protein virB11, putative Type II/IV secretion system protein complement(15102..16133) Escherichia coli UMN026 7169469 YP_002381206.1 CDS p2ECUMN_0024 NC_011739.1 16135 17340 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative pilx10 protein, putative bacterial conjugation TrbI-like protein complement(16135..17340) Escherichia coli UMN026 7169468 YP_002381207.1 CDS p2ECUMN_0025 NC_011739.1 17337 18266 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative pilx9 protein, putative conjugal transfer protein, putative exported protein complement(17337..18266) Escherichia coli UMN026 7169466 YP_002381208.1 CDS p2ECUMN_0026 NC_011739.1 18271 18984 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative pilx8 protein complement(18271..18984) Escherichia coli UMN026 7169422 YP_002381209.1 CDS p2ECUMN_0027 NC_011739.1 19229 20362 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative TrbL/VirB6 plasmid conjugal transfer protein complement(19229..20362) Escherichia coli UMN026 7169424 YP_002381210.1 CDS p2ECUMN_0028 NC_011739.1 20372 20599 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein; putative exported protein complement(20372..20599) Escherichia coli UMN026 7169444 YP_002381211.1 CDS p2ECUMN_0029 NC_011739.1 20600 21358 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Pilx5/VirB5 protein, putative conjugal transfer protein, putative exported protein complement(20600..21358) Escherichia coli UMN026 7169443 YP_002381212.1 CDS p2ECUMN_0030 NC_011739.1 21369 24122 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Pilx3-4/VirB3-4 protein, putative conjugal transfer protein complement(21369..24122) Escherichia coli UMN026 7169442 YP_002381213.1 CDS p2ECUMN_0031 NC_011739.1 24144 24473 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative Pilx2 protein complement(24144..24473) Escherichia coli UMN026 7169441 YP_002381214.1 CDS p2ECUMN_0032 NC_011739.1 24418 25065 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Pilx1/VirB1 protein, putative conjugal transfer protein, putative exported protein complement(24418..25065) Escherichia coli UMN026 7169440 YP_002381215.1 CDS p2ECUMN_0033 NC_011739.1 25111 25332 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(25111..25332) Escherichia coli UMN026 7169439 YP_002381216.1 CDS p2ECUMN_0034 NC_011739.1 25802 25975 R Evidence 6 : Doubtful CDS; hypothetical protein complement(25802..25975) Escherichia coli UMN026 7169438 YP_002381217.1 CDS taxC NC_011739.1 26122 27294 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Nickase complement(26122..27294) Escherichia coli UMN026 7169437 YP_002381218.1 CDS p2ECUMN_0036 NC_011739.1 27291 27938 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(27291..27938) Escherichia coli UMN026 7169445 YP_002381219.1 CDS p2ECUMN_0037 NC_011739.1 27942 28091 R Evidence 6 : Doubtful CDS; hypothetical protein complement(27942..28091) Escherichia coli UMN026 7169436 YP_002381220.1 CDS p2ECUMN_0038 NC_011739.1 28152 28424 R Evidence 6 : Doubtful CDS; hypothetical protein complement(28152..28424) Escherichia coli UMN026 7169435 YP_002381221.1 CDS p2ECUMN_0039 NC_011739.1 28437 28634 R Evidence 6 : Doubtful CDS; hypothetical protein complement(28437..28634) Escherichia coli UMN026 7169434 YP_002381222.1 CDS p2ECUMN_0040 NC_011739.1 28655 28966 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(28655..28966) Escherichia coli UMN026 7169433 YP_002381223.1 CDS p2ECUMN_0041 NC_011739.1 28963 29379 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(28963..29379) Escherichia coli UMN026 7169432 YP_002381224.1 CDS p2ECUMN_0042 NC_011739.1 29389 29730 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative GMP synthase complement(29389..29730) Escherichia coli UMN026 7169431 YP_002381225.1 CDS p2ECUMN_0043 NC_011739.1 29690 30049 R Evidence 6 : Doubtful CDS; hypothetical protein complement(29690..30049) Escherichia coli UMN026 7169430 YP_002381226.1 CDS p2ECUMN_0045 NC_011739.1 30142 30369 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative YajA protein, putative regulator complement(30142..30369) Escherichia coli UMN026 7169429 YP_002381227.1 CDS p2ECUMN_0046 NC_011739.1 30356 30607 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(30356..30607) Escherichia coli UMN026 7169428 YP_002381228.1 CDS p2ECUMN_0047 NC_011739.1 30604 31146 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(30604..31146) Escherichia coli UMN026 7169427 YP_002381229.1 CDS p2ECUMN_0048 NC_011739.1 31251 32129 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative DnaJ-class molecular chaperone complement(31251..32129) Escherichia coli UMN026 7169426 YP_002381230.1 CDS p2ECUMN_0049 NC_011739.1 32406 32756 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(32406..32756) Escherichia coli UMN026 7169425 YP_002381231.1 CDS p2ECUMN_0050 NC_011739.1 32753 33088 R Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein, putative phage origin complement(32753..33088) Escherichia coli UMN026 7169446 YP_002405907.1 CDS RepFIB NC_011749.1 101 1078 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8356112, 2651415, 8320218; Product type r : regulator; replication protein 101..1078 Escherichia coli UMN026 7144300 YP_002405908.1 CDS int NC_011749.1 1321 2061 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; site-specific recombinase complement(1321..2061) Escherichia coli UMN026 7144240 YP_002405909.1 CDS p1ECUMN_0003 NC_011749.1 2737 3906 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2737..3906 Escherichia coli UMN026 7144229 YP_002405910.1 CDS insC NC_011749.1 5621 6031 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; hypothetical protein complement(5621..6031) Escherichia coli UMN026 7144302 YP_002405911.1 CDS p1ECUMN_0005 NC_011749.1 6268 8238 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11179376, 7768795, 9393841, 9680204, 9157252; Product type prc : receptor; Hemin receptor precursor 6268..8238 Escherichia coli UMN026 7144227 YP_002405912.1 CDS p1ECUMN_0006 NC_011749.1 8245 9036 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 8245..9036 Escherichia coli UMN026 7144303 YP_002405913.1 CDS p1ECUMN_0007 NC_011749.1 9099 9617 R Evidence 4 : Homologs of previously reported genes of unknown function; transposase complement(9099..9617) Escherichia coli UMN026 7144304 YP_002405914.1 CDS p1ECUMN_0008 NC_011749.1 9775 10557 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase/IS protein complement(9775..10557) Escherichia coli UMN026 7144305 YP_002405915.1 CDS p1ECUMN_0009 NC_011749.1 10554 11576 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF2 IS100 complement(10554..11576) Escherichia coli UMN026 7144306 YP_002405916.1 CDS p1ECUMN_0010 NC_011749.1 11590 12348 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fragment of transposase ORF2, ISEc8, IS66 family complement(11590..12348) Escherichia coli UMN026 7144307 YP_002405917.1 CDS p1ECUMN_0011 NC_011749.1 12350 12607 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase IS66 family (part 1) complement(12350..12607) Escherichia coli UMN026 7144308 YP_002405918.1 CDS p1ECUMN_0012 NC_011749.1 12656 13003 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF2, ISEc8, IS66 family complement(12656..13003) Escherichia coli UMN026 7144309 YP_002405919.1 CDS p1ECUMN_0013 NC_011749.1 13000 13404 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF 1, ISEc8, IS66 family complement(13000..13404) Escherichia coli UMN026 7144310 YP_002405920.1 CDS p1ECUMN_0015 NC_011749.1 13906 15429 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; reverse transcriptase-like protein from prophage or plasmid complement(13906..15429) Escherichia coli UMN026 7144312 YP_002405921.1 CDS senB NC_011749.1 17680 18954 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; Enterotoxin TieB protein complement(17680..18954) Escherichia coli UMN026 7144316 YP_002405922.1 CDS CjrC NC_011749.1 18924 21185 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11395459; Product type rc : receptor; outer membrane colicin Js receptor complement(18924..21185) Escherichia coli UMN026 7144245 YP_002405923.1 CDS CjrB NC_011749.1 21354 22130 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11395459; Product type rc : receptor; periplasmic colicin Js sensitivity protein complement(21354..22130) Escherichia coli UMN026 7144212 YP_002405924.1 CDS p1ECUMN_0022 NC_011749.1 22138 23055 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11395459; iron-regulated protein cjrA complement(22138..23055) Escherichia coli UMN026 7144211 YP_002405925.1 CDS p1ECUMN_0023 NC_011749.1 23345 23605 R hypothetical protein complement(23345..23605) Escherichia coli UMN026 7144317 YP_002405926.1 CDS p1ECUMN_0024 NC_011749.1 23602 23892 R Rep protein (fragment) complement(23602..23892) Escherichia coli UMN026 7144318 YP_002405927.1 CDS p1ECUMN_0025 NC_011749.1 25237 25446 D Evidence 6 : Doubtful CDS; hypothetical protein 25237..25446 Escherichia coli UMN026 7144319 YP_002405928.1 CDS imm NC_011749.1 25464 25799 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3531169, 7972047; Product type m : membrane component; Colicin-Ia immunity protein complement(25464..25799) Escherichia coli UMN026 7144320 YP_002405929.1 CDS p1ECUMN_0027 NC_011749.1 25777 25995 R Evidence 6 : Doubtful CDS; hypothetical protein complement(25777..25995) Escherichia coli UMN026 7144217 YP_002405930.1 CDS ybaA NC_011749.1 25928 26275 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 25928..26275 Escherichia coli UMN026 7144321 YP_002405931.1 CDS p1ECUMN_0029 NC_011749.1 26295 26804 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(26295..26804) Escherichia coli UMN026 7144283 YP_002405932.1 CDS ydfA NC_011749.1 26801 27061 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(26801..27061) Escherichia coli UMN026 7144322 YP_002405933.1 CDS p1ECUMN_0031 NC_011749.1 27163 27489 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS629 27163..27489 Escherichia coli UMN026 7144289 YP_002405934.1 CDS p1ECUMN_0033 NC_011749.1 28560 29063 D Evidence 4 : Homologs of previously reported genes of unknown function; transposase 28560..29063 Escherichia coli UMN026 7144324 YP_002405935.1 CDS p1ECUMN_0034 NC_011749.1 29102 29701 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(29102..29701) Escherichia coli UMN026 7144325 YP_002405936.1 CDS p1ECUMN_0035 NC_011749.1 29397 29846 R glucose-1-phosphatase precursor complement(29397..29846) Escherichia coli UMN026 7144326 YP_002405937.1 CDS p1ECUMN_0036 NC_011749.1 29968 30453 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(29968..30453) Escherichia coli UMN026 7144327 YP_002405938.1 CDS p1ECUMN_0037 NC_011749.1 30478 31032 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioredoxin-family protein complement(30478..31032) Escherichia coli UMN026 7144328 YP_002405939.1 CDS p1ECUMN_0038 NC_011749.1 30950 31645 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter ATP-binding protein complement(30950..31645) Escherichia coli UMN026 7144329 YP_002405940.1 CDS p1ECUMN_0039 NC_011749.1 31650 32810 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(31650..32810) Escherichia coli UMN026 7144330 YP_002405941.1 CDS p1ECUMN_0040 NC_011749.1 32770 34053 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(32770..34053) Escherichia coli UMN026 7144331 YP_002405942.1 CDS p1ECUMN_0041 NC_011749.1 34056 35435 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(34056..35435) Escherichia coli UMN026 7144332 YP_002405943.1 CDS p1ECUMN_0042 NC_011749.1 35539 36069 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(35539..36069) Escherichia coli UMN026 7144333 YP_002405944.1 CDS p1ECUMN_0043 NC_011749.1 36107 38053 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(36107..38053) Escherichia coli UMN026 7144334 YP_002405945.1 CDS p1ECUMN_0045 NC_011749.1 38340 39155 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C complement(38340..39155) Escherichia coli UMN026 7144335 YP_002405946.1 CDS scsD NC_011749.1 39338 39844 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; copper-sensitivity suppressor D complement(39338..39844) Escherichia coli UMN026 7144336 YP_002405947.1 CDS scsC NC_011749.1 39834 40061 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; copper-sensitivity suppressor C complement(39834..40061) Escherichia coli UMN026 7144244 YP_002405948.1 CDS p1ECUMN_0048 NC_011749.1 40142 40294 R Evidence 7 : Gene remnant; Product type e : enzyme; transposase IS26 fragment complement(40142..40294) Escherichia coli UMN026 7144243 YP_002405949.1 CDS insA NC_011749.1 40455 40730 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 40455..40730 Escherichia coli UMN026 7144242 YP_002405950.1 CDS insB NC_011749.1 40649 41152 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; transposase 40649..41152 Escherichia coli UMN026 7144221 YP_002405951.1 CDS p1ECUMN_0051 NC_011749.1 41203 42330 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase, IS4 family, IS10 41203..42330 Escherichia coli UMN026 7144224 YP_002405952.1 CDS tetD NC_011749.1 42340 42756 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094472; Product type pr : regulator; transcriptionnal regulator involved in tetracycline resistance complement(42340..42756) Escherichia coli UMN026 7144338 YP_002405953.1 CDS tetC NC_011749.1 42769 43437 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptionnal regulator involved in tetracycline resistance 42769..43437 Escherichia coli UMN026 7144249 YP_002405954.1 CDS tetA NC_011749.1 43550 44803 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6319234, 6298728, 1848846, 2168416, 8995300; Product type t : transporter; tetracycline efflux transporter complement(43550..44803) Escherichia coli UMN026 7144248 YP_002405955.1 CDS tetR NC_011749.1 44834 45460 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330687, 6311683, 3062183; Product type r : regulator; TetR family transcriptional regulator 44834..45460 Escherichia coli UMN026 7144247 YP_002405956.1 CDS jemC NC_011749.1 45438 46124 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; ArsR family regulatory protein complement(45438..46124) Escherichia coli UMN026 7144250 YP_002405957.1 CDS p1ECUMN_0057 NC_011749.1 46132 46629 R Evidence 4 : Homologs of previously reported genes of unknown function; regulatory protein in the aminoacid metabolism complement(46132..46629) Escherichia coli UMN026 7144232 YP_002405958.1 CDS insB NC_011749.1 46771 47274 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; transposase complement(46771..47274) Escherichia coli UMN026 7144340 YP_002405959.1 CDS insA NC_011749.1 47193 47468 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA complement(47193..47468) Escherichia coli UMN026 7144225 YP_002405960.1 CDS insB NC_011749.1 47802 48305 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; transposase complement(47802..48305) Escherichia coli UMN026 7144341 YP_002405961.1 CDS insA NC_011749.1 48224 48499 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA complement(48224..48499) Escherichia coli UMN026 7144226 YP_002405962.1 CDS p1ECUMN_0064 NC_011749.1 48647 48751 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(48647..48751) Escherichia coli UMN026 7144223 YP_002405963.1 CDS pemK NC_011749.1 48748 49212 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; Plasmid stable inheritance protein complement(48748..49212) Escherichia coli UMN026 7144342 YP_002405964.1 CDS pemI NC_011749.1 49082 49339 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2832364; Product type r : regulator; Plasmid stable inheritance repressor protein complement(49082..49339) Escherichia coli UMN026 7144235 YP_002405965.1 CDS p1ECUMN_0067 NC_011749.1 49400 49621 R Evidence 6 : Doubtful CDS; hypothetical protein complement(49400..49621) Escherichia coli UMN026 7144234 YP_002405966.1 CDS p1ECUMN_0068 NC_011749.1 49432 50085 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(49432..50085) Escherichia coli UMN026 7144343 YP_002405967.1 CDS repA NC_011749.1 51023 51892 R RepA; replication protein complement(51023..51892) Escherichia coli UMN026 7144344 YP_002405968.1 CDS repB NC_011749.1 52180 52440 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; replication protein complement(52180..52440) Escherichia coli UMN026 7144220 YP_002405969.1 CDS yihA NC_011749.1 52680 53270 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(52680..53270) Escherichia coli UMN026 7144239 YP_002405970.1 CDS p1ECUMN_0072 NC_011749.1 53308 53517 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; hemolysin expression-modulating protein hmo complement(53308..53517) Escherichia coli UMN026 7144294 YP_002405971.1 CDS p1ECUMN_0073 NC_011749.1 53563 54099 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nuclease complement(53563..54099) Escherichia coli UMN026 7144345 YP_002405972.1 CDS p1ECUMN_0074 NC_011749.1 54269 54481 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(54269..54481) Escherichia coli UMN026 7144346 YP_002405973.1 CDS finO NC_011749.1 54610 55170 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3027040, 2951652; Product type r : regulator; conjugal transfer fertility inhibition protein FinO complement(54610..55170) Escherichia coli UMN026 7144347 YP_002405974.1 CDS p1ECUMN_0076 NC_011749.1 55273 56133 R Evidence 4 : Homologs of previously reported genes of unknown function; alpha/beta hydrolase complement(55273..56133) Escherichia coli UMN026 7144213 YP_002405975.1 CDS traX NC_011749.1 56192 57409 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8444800, 7768788, 1916281, 7915817, 2164585; Product type e : enzyme; F pilin acetylase complement(56192..57409) Escherichia coli UMN026 7144348 YP_002405976.1 CDS traI NC_011749.1 56958 62228 R cleaves origin of transfer and unwinds; oriT relaxase; conjugal transfer protein TraI complement(56958..62228) Escherichia coli UMN026 7144272 YP_002405977.1 CDS p1ECUMN_0079 NC_011749.1 62228 64525 R type IV secretion system coupling protein; similar to F plasmid TraD; conjugal transfer protein TraD complement(62228..64525) Escherichia coli UMN026 7144258 YP_002405978.1 CDS p1ECUMN_0080 NC_011749.1 64576 65379 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(64576..65379) Escherichia coli UMN026 7144349 YP_002405979.1 CDS traT NC_011749.1 65516 66250 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1359384, 3323526, 7915817, 2087219, 6995306, 9696748, 1730875, 6238226; Product type m : membrane component; conjugal transfer protein TraT complement(65516..66250) Escherichia coli UMN026 7144350 YP_002405980.1 CDS traS NC_011749.1 66296 66781 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3323526; Product type m : membrane component; hypothetical protein complement(66296..66781) Escherichia coli UMN026 7144268 YP_002405981.1 CDS traG NC_011749.1 66797 69619 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1348105, 7915817; Product type m : membrane component; conjugal transfer protein TraG complement(66797..69619) Escherichia coli UMN026 7144267 YP_002405982.1 CDS traH NC_011749.1 69616 70998 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1348105, 7915817, 2656408; Product type s : structure; conjugal transfer protein TraH complement(69616..70998) Escherichia coli UMN026 7144256 YP_002405983.1 CDS trbF NC_011749.1 70976 71401 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2656408, 7915817, 2536655; Product type pm : membrane component; conjugal transfer protein TrbF complement(70976..71401) Escherichia coli UMN026 7144257 YP_002405984.1 CDS trbJ NC_011749.1 71349 71729 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2536655, 7915817; Product type pm : membrane component; conjugal transfer protein TrbJ complement(71349..71729) Escherichia coli UMN026 7144277 YP_002405985.1 CDS trbB NC_011749.1 71626 72171 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2536655, 7915817; Product type pf : factor; conjugal transfer protein TrbB complement(71626..72171) Escherichia coli UMN026 7144279 YP_002405986.1 CDS TraQ NC_011749.1 72158 72442 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2536655, 7915817; Product type m : membrane component; conjugal transfer protein TraQ complement(72158..72442) Escherichia coli UMN026 7144274 YP_002405987.1 CDS traF NC_011749.1 73194 73967 R type IV secretion system pilus assembly protein; similar to F plasmid TraF; conjugal transfer protein TraF complement(73194..73967) Escherichia coli UMN026 7144265 YP_002405988.1 CDS trbE NC_011749.1 73930 74190 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12533481, 1593622, 7915817; Product type m : membrane component; conjugal transfer protein TrbE complement(73930..74190) Escherichia coli UMN026 7144255 YP_002405989.1 CDS traN NC_011749.1 74214 76064 R TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN complement(74214..76064) Escherichia coli UMN026 7144276 YP_002405990.1 CDS trbC NC_011749.1 76061 76711 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2050638, 7915817, 2198250, 1593622; Product type s : structure; conjugal transfer protein TrbC complement(76061..76711) Escherichia coli UMN026 7144263 YP_002405991.1 CDS p1ECUMN_0094 NC_011749.1 76708 77019 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(76708..77019) Escherichia coli UMN026 7144275 YP_002405992.1 CDS traU NC_011749.1 77043 78035 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2198250, 7915817, 2050638, 1355084; Product type s : structure; conjugal transfer protein TraU complement(77043..78035) Escherichia coli UMN026 7144351 YP_002405993.1 CDS traW NC_011749.1 78032 78778 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292150, 1355084, 7915817, 2198250; Product type s : structure; conjugal transfer protein TraW complement(78032..78778) Escherichia coli UMN026 7144269 YP_002405994.1 CDS trbI NC_011749.1 78661 79047 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292150; Product type m : membrane component; conjugal transfer protein TrbI complement(78661..79047) Escherichia coli UMN026 7144271 YP_002405995.1 CDS traC NC_011749.1 79044 81674 R similar to VirB4; conjugal transfer protein TraC complement(79044..81674) Escherichia coli UMN026 7144278 YP_002405996.1 CDS p1ECUMN_0099 NC_011749.1 81800 81973 R Evidence 6 : Doubtful CDS; hypothetical protein complement(81800..81973) Escherichia coli UMN026 7144253 YP_002405997.1 CDS p1ECUMN_0100 NC_011749.1 82041 82259 R Evidence 6 : Doubtful CDS; hypothetical protein complement(82041..82259) Escherichia coli UMN026 7144352 YP_002405998.1 CDS yfiA NC_011749.1 82339 82854 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(82339..82854) Escherichia coli UMN026 7144353 YP_002405999.1 CDS traR NC_011749.1 82805 83026 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8021201, 7915817; Product type pf : factor; conjugal transfer protein TraR complement(82805..83026) Escherichia coli UMN026 7144293 YP_002406000.1 CDS traV NC_011749.1 83161 83676 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8021201, 7915817; Product type lp : lipoprotein; conjugal transfer protein TraV complement(83161..83676) Escherichia coli UMN026 7144266 YP_002406001.1 CDS p1ECUMN_0104 NC_011749.1 83673 83906 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8021201, 7915817; conjugal transfer protein TrbG complement(83673..83906) Escherichia coli UMN026 7144270 YP_002406002.1 CDS p1ECUMN_0105 NC_011749.1 83918 84271 R Evidence 4 : Homologs of previously reported genes of unknown function; conjugal transfer protein TrbD complement(83918..84271) Escherichia coli UMN026 7144354 YP_002406003.1 CDS traP NC_011749.1 84225 84815 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; conjugal transfer protein TraP complement(84225..84815) Escherichia coli UMN026 7144355 YP_002406004.1 CDS traB NC_011749.1 84805 86232 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7915817, 8655498; Product type s : structure; conjugal transfer protein TraB complement(84805..86232) Escherichia coli UMN026 7144264 YP_002406005.1 CDS traK NC_011749.1 86232 86960 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655498; Product type s : structure; conjugal transfer protein TraK complement(86232..86960) Escherichia coli UMN026 7144252 YP_002406006.1 CDS traE NC_011749.1 86947 87513 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817; Product type m : membrane component; conjugal transfer protein TraE complement(86947..87513) Escherichia coli UMN026 7144260 YP_002406007.1 CDS traL NC_011749.1 87535 87846 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817, 2564189, 8655498; Product type m : membrane component; conjugal transfer protein TraL complement(87535..87846) Escherichia coli UMN026 7144254 YP_002406008.1 CDS traA NC_011749.1 87861 88220 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817, 2999074; Product type s : structure; conjugal transfer pilin subunit TraA complement(87861..88220) Escherichia coli UMN026 7144261 YP_002406009.1 CDS p1ECUMN_0112 NC_011749.1 88254 88430 R Evidence 6 : Doubtful CDS; hypothetical protein complement(88254..88430) Escherichia coli UMN026 7144251 YP_002406010.1 CDS insH NC_011749.1 88290 89306 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; transposase 88290..89306 Escherichia coli UMN026 7144301 YP_002406011.1 CDS traY NC_011749.1 89453 89680 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; conjugal transfer protein TraY complement(89453..89680) Escherichia coli UMN026 7144228 YP_002406012.1 CDS traJ NC_011749.1 89774 90520 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3012278, 2564189; Product type r : regulator; conjugation transfer regulator complement(89774..90520) Escherichia coli UMN026 7144273 YP_002406013.1 CDS traM NC_011749.1 90654 91037 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995191; Product type f : factor; conjugal transfer protein TraM complement(90654..91037) Escherichia coli UMN026 7144214 YP_002406014.1 CDS yubQ NC_011749.1 91368 91970 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; lytic transglycosylase 91368..91970 Escherichia coli UMN026 7144262 YP_002406015.1 CDS yubP NC_011749.1 92266 93171 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(92266..93171) Escherichia coli UMN026 7144299 YP_002406016.1 CDS yubO NC_011749.1 93206 93493 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(93206..93493) Escherichia coli UMN026 7144298 YP_002406017.1 CDS flmC NC_011749.1 94413 94625 R Mok; similar to F leading maintenance protein C; modulator of post-segregation killing protein complement(94413..94625) Escherichia coli UMN026 7144297 YP_002406018.1 CDS psiA NC_011749.1 94843 95562 R PsiA; plasmid SOS inhibition protein A complement(94843..95562) Escherichia coli UMN026 7144215 YP_002406019.1 CDS psiB NC_011749.1 95559 95996 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9987116, 10537187; Product type f : factor; plasmid SOS inhibition protein B complement(95559..95996) Escherichia coli UMN026 7144236 YP_002406020.1 CDS ycjA NC_011749.1 96048 98096 R Evidence 4 : Homologs of previously reported genes of unknown function; ParB-like nuclease complement(96048..98096) Escherichia coli UMN026 7144237 YP_002406021.1 CDS yubL NC_011749.1 98065 98325 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(98065..98325) Escherichia coli UMN026 7144286 YP_002406022.1 CDS ssb NC_011749.1 98355 98921 R Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; single-stranded DNA-binding protein complement(98355..98921) Escherichia coli UMN026 7144296 YP_002406023.1 CDS ydcA NC_011749.1 99708 100271 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; adenine-specific DNA methylase complement(99708..100271) Escherichia coli UMN026 7144246 YP_002406024.1 CDS ydbA NC_011749.1 100318 101679 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(100318..101679) Escherichia coli UMN026 7144288 YP_002406025.1 CDS p1ECUMN_0130 NC_011749.1 102924 103115 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(102924..103115) Escherichia coli UMN026 7144287 YP_002406026.1 CDS p1ECUMN_0131 NC_011749.1 103112 103486 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(103112..103486) Escherichia coli UMN026 7144200 YP_002406027.1 CDS p1ECUMN_0132 NC_011749.1 103583 104008 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; antirestriction protein complement(103583..104008) Escherichia coli UMN026 7144201 YP_002406028.1 CDS ycfA NC_011749.1 104424 105194 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(104424..105194) Escherichia coli UMN026 7144202 YP_002406029.1 CDS yfcB NC_011749.1 105239 105673 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(105239..105673) Escherichia coli UMN026 7144285 YP_002406030.1 CDS yfeB NC_011749.1 105687 105908 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(105687..105908) Escherichia coli UMN026 7144291 YP_002406031.1 CDS p1ECUMN_0137 NC_011749.1 105909 106592 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methylase complement(105909..106592) Escherichia coli UMN026 7144292 YP_002406032.1 CDS yccB NC_011749.1 106976 107947 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(106976..107947) Escherichia coli UMN026 7144203 YP_002406033.1 CDS yuaZ NC_011749.1 107916 108185 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(107916..108185) Escherichia coli UMN026 7144284 YP_002406034.1 CDS p1ECUMN_0141 NC_011749.1 108297 109517 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase complement(108297..109517) Escherichia coli UMN026 7144295 YP_002406035.1 CDS p1ECUMN_0142 NC_011749.1 109536 110054 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(109536..110054) Escherichia coli UMN026 7144204 YP_002406036.1 CDS impC NC_011749.1 110189 110437 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; UV protection and mutation protein 110189..110437 Escherichia coli UMN026 7144205 YP_002406037.1 CDS impA NC_011749.1 110434 110871 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2129552; Product type f : factor; UV protection and mutation protein 110434..110871 Escherichia coli UMN026 7144219 YP_002406038.1 CDS istA NC_011749.1 111994 113166 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF1, IS21 111994..113166 Escherichia coli UMN026 7144280 YP_002406039.1 CDS istB NC_011749.1 113163 113963 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF2, IS21, ATP-binding protein 113163..113963 Escherichia coli UMN026 7144230 YP_002406040.1 CDS p1ECUMN_0150 NC_011749.1 114281 114709 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; stable plasmid inheritance protein complement(114281..114709) Escherichia coli UMN026 7144281 YP_002406041.1 CDS parM NC_011749.1 114678 115649 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3172224, 3023637, 12486014; Product type f : factor; Plasmid segregation protein complement(114678..115649) Escherichia coli UMN026 7144206 YP_002406042.1 CDS p1ECUMN_0152 NC_011749.1 115878 116522 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 115878..116522 Escherichia coli UMN026 7144233 YP_002406043.1 CDS p1ECUMN_0153 NC_011749.1 116516 116791 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 116516..116791 Escherichia coli UMN026 7144207 YP_002406044.1 CDS resD NC_011749.1 116929 117738 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3027661, 3007930, 6327993; Product type e : enzyme; resolvase complement(116929..117738) Escherichia coli UMN026 7144208 YP_002406045.1 CDS ccdB NC_011749.1 117739 118071 R controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB complement(117739..118071) Escherichia coli UMN026 7144241 YP_002406046.1 CDS ccdA NC_011749.1 118046 118324 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; plasmid maintenance protein CcdA complement(118046..118324) Escherichia coli UMN026 7144210 YP_002406047.1 CDS ydiA NC_011749.1 120586 121227 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 120586..121227 Escherichia coli UMN026 7144282 YP_002406048.1 CDS p1ECUMN_0160 NC_011749.1 121095 121415 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(121095..121415) Escherichia coli UMN026 7144290 YP_002410781.1 CDS thrL NC_011751.1 149 214 D involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 149..214 Escherichia coli UMN026 7159698 YP_002410782.1 CDS thrA NC_011751.1 295 2757 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 295..2757 Escherichia coli UMN026 7158067 YP_002410783.1 CDS thrB NC_011751.1 2759 3691 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2759..3691 Escherichia coli UMN026 7158064 YP_002410784.1 CDS thrC NC_011751.1 3692 4978 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3692..4978 Escherichia coli UMN026 7158065 YP_002410785.1 CDS yaaX NC_011751.1 5192 5488 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5192..5488 Escherichia coli UMN026 7158066 YP_002410786.1 CDS yaaA NC_011751.1 5641 6417 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5641..6417) Escherichia coli UMN026 7158263 YP_002410787.1 CDS yaaJ NC_011751.1 6487 7917 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino acid sodium/proton transporter complement(6487..7917) Escherichia coli UMN026 7158258 YP_002410788.1 CDS talB NC_011751.1 8196 9149 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 92334977, 11298760, 7592346, 8805555, 9007983, 9298646; Product type e : enzyme; transaldolase B 8196..9149 Escherichia coli UMN026 7158261 YP_002410789.1 CDS mogA NC_011751.1 9264 9851 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9264..9851 Escherichia coli UMN026 7158020 YP_002410790.1 CDS yaaH NC_011751.1 9886 10452 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(9886..10452) Escherichia coli UMN026 7157160 YP_002410791.1 CDS htpY NC_011751.1 10601 11314 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8478327; Product type r : regulator; hypothetical protein complement(10601..11314) Escherichia coli UMN026 7158259 YP_002410792.1 CDS yaaI NC_011751.1 11340 11744 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(11340..11744) Escherichia coli UMN026 7156728 YP_002410793.1 CDS dnaK NC_011751.1 12120 14036 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12120..14036 Escherichia coli UMN026 7158260 YP_002410794.1 CDS dnaJ NC_011751.1 14125 15255 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 14125..15255 Escherichia coli UMN026 7158099 YP_002410795.1 CDS nhaA NC_011751.1 16097 17263 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 16097..17263 Escherichia coli UMN026 7157951 YP_002410796.1 CDS nhaR NC_011751.1 17323 18228 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 17323..18228 Escherichia coli UMN026 7157271 YP_002410797.1 CDS ECUMN_0018 NC_011751.1 18266 19225 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(18266..19225) Escherichia coli UMN026 7157273 YP_002410798.1 CDS ECUMN_0019 NC_011751.1 19238 21688 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative fimbrial biogenesis outer membrane usher protein complement(19238..21688) Escherichia coli UMN026 7154603 YP_002410799.1 CDS ECUMN_0020 NC_011751.1 21701 22384 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative membrane-associated pilin chaperone complement(21701..22384) Escherichia coli UMN026 7154604 YP_002410800.1 CDS ECUMN_0021 NC_011751.1 22434 22967 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like protein complement(22434..22967) Escherichia coli UMN026 7154605 YP_002410801.1 CDS ECUMN_0022 NC_011751.1 23268 24689 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(23268..24689) Escherichia coli UMN026 7154606 YP_002410802.1 CDS rpsT NC_011751.1 25173 25436 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(25173..25436) Escherichia coli UMN026 7154607 YP_002410803.1 CDS yaaY NC_011751.1 25539 25757 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 25539..25757 Escherichia coli UMN026 7157786 YP_002410804.1 CDS ribF NC_011751.1 25765 26706 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 25765..26706 Escherichia coli UMN026 7158264 YP_002410805.1 CDS ileS NC_011751.1 26749 29565 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 26749..29565 Escherichia coli UMN026 7157687 YP_002410806.1 CDS lspA NC_011751.1 29565 30059 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 29565..30059 Escherichia coli UMN026 7156796 YP_002410807.1 CDS fkpB NC_011751.1 30146 30595 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97332650, 2011499; Product type e : enzyme; FKBP-type peptidyl-prolyl cis-trans isomerase 30146..30595 Escherichia coli UMN026 7157019 YP_002410808.1 CDS ispH NC_011751.1 30597 31547 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 30597..31547 Escherichia coli UMN026 7156374 YP_002410809.1 CDS rihC NC_011751.1 31613 32527 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 31613..32527 Escherichia coli UMN026 7156868 YP_002410810.1 CDS dapB NC_011751.1 32694 33515 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 32694..33515 Escherichia coli UMN026 7157690 YP_002410811.1 CDS carA NC_011751.1 33971 35119 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 33971..35119 Escherichia coli UMN026 7156108 YP_002410812.1 CDS carB NC_011751.1 35137 38355 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 35137..38355 Escherichia coli UMN026 7155918 YP_002410813.1 CDS ECUMN_0035 NC_011751.1 38363 38581 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7815937, 6308632; hypothetical protein complement(38363..38581) Escherichia coli UMN026 7155919 YP_002410814.1 CDS caiF NC_011751.1 38616 39011 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 38616..39011 Escherichia coli UMN026 7154608 YP_002410815.1 CDS caiE NC_011751.1 39217 39807 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(39217..39807) Escherichia coli UMN026 7155915 YP_002410816.2 CDS caiD NC_011751.1 39813 40598 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(39813..40598) Escherichia coli UMN026 7155914 YP_002410817.1 CDS caiC NC_011751.1 40707 42275 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15731894, 97189569, 7815937; Product type e : enzyme; putative crotonobetaine/carnitine-CoA ligase complement(40707..42275) Escherichia coli UMN026 7155913 YP_002410818.1 CDS caiB NC_011751.1 42334 43551 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(42334..43551) Escherichia coli UMN026 7155912 YP_002410819.1 CDS caiA NC_011751.1 43680 44822 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(43680..44822) Escherichia coli UMN026 7155911 YP_002410820.1 CDS caiT NC_011751.1 44853 46367 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(44853..46367) Escherichia coli UMN026 7155910 YP_002410821.1 CDS fixA NC_011751.1 46840 47610 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA 46840..47610 Escherichia coli UMN026 7155916 YP_002410822.1 CDS fixB NC_011751.1 47625 48566 D involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB 47625..48566 Escherichia coli UMN026 7156368 YP_002410823.1 CDS fixC NC_011751.1 48617 49903 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC 48617..49903 Escherichia coli UMN026 7156369 YP_002410824.1 CDS fixX NC_011751.1 49900 50187 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96066354, 12081978; Product type pc : putative carrier; putative 4Fe-4S ferredoxin 49900..50187 Escherichia coli UMN026 7156370 YP_002410825.1 CDS yaaU NC_011751.1 50246 51577 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 50246..51577 Escherichia coli UMN026 7156371 YP_002410826.1 CDS kefF NC_011751.1 51685 52215 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 51685..52215 Escherichia coli UMN026 7158262 YP_002410827.1 CDS kefC NC_011751.1 52208 54070 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 52208..54070 Escherichia coli UMN026 7156905 YP_002410828.1 CDS folA NC_011751.1 54262 54741 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 54262..54741 Escherichia coli UMN026 7156904 YP_002410829.1 CDS apaH NC_011751.1 54819 55661 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(54819..55661) Escherichia coli UMN026 7156423 YP_002410830.1 CDS apaG NC_011751.1 55668 56045 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(55668..56045) Escherichia coli UMN026 7155749 YP_002410831.1 CDS ksgA NC_011751.1 56048 56869 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(56048..56869) Escherichia coli UMN026 7155748 YP_002410832.1 CDS pdxA NC_011751.1 56866 57855 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(56866..57855) Escherichia coli UMN026 7156918 YP_002410833.1 CDS surA NC_011751.1 57855 59141 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(57855..59141) Escherichia coli UMN026 7157404 YP_002410834.1 CDS imp NC_011751.1 59194 61548 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(59194..61548) Escherichia coli UMN026 7158013 YP_002410835.1 CDS djlA NC_011751.1 61803 62618 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 61803..62618 Escherichia coli UMN026 7156809 YP_002410836.1 CDS ECUMN_0058 NC_011751.1 62913 63644 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 62913..63644 Escherichia coli UMN026 7156172 YP_002410837.1 CDS rluA NC_011751.1 64052 64711 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(64052..64711) Escherichia coli UMN026 7154609 YP_002410838.1 CDS hepA NC_011751.1 64723 67629 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(64723..67629) Escherichia coli UMN026 7157699 YP_002410839.1 CDS polB NC_011751.1 67793 70144 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(67793..70144) Escherichia coli UMN026 7156662 YP_002410840.1 CDS araD NC_011751.1 70219 70914 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(70219..70914) Escherichia coli UMN026 7157486 YP_002410841.1 CDS araA NC_011751.1 71199 72701 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(71199..72701) Escherichia coli UMN026 7155760 YP_002410842.1 CDS araB NC_011751.1 72712 74412 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(72712..74412) Escherichia coli UMN026 7155757 YP_002410843.1 CDS araC NC_011751.1 74751 75629 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 74751..75629 Escherichia coli UMN026 7155758 YP_002410844.1 CDS yabI NC_011751.1 75715 76479 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 75715..76479 Escherichia coli UMN026 7155759 YP_002410845.1 CDS thiQ NC_011751.1 76593 77291 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(76593..77291) Escherichia coli UMN026 7158265 YP_002410846.1 CDS thiP NC_011751.1 77275 78885 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(77275..78885) Escherichia coli UMN026 7158062 YP_002410847.1 CDS tbpA NC_011751.1 78861 79844 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(78861..79844) Escherichia coli UMN026 7158061 YP_002410848.1 CDS ECUMN_0070 NC_011751.1 79888 80112 R Evidence 6 : Doubtful CDS; hypothetical protein complement(79888..80112) Escherichia coli UMN026 7158034 YP_002410849.1 CDS ECUMN_0071 NC_011751.1 80215 81051 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 80215..81051 Escherichia coli UMN026 7154610 YP_002410850.1 CDS sgrR NC_011751.1 81548 83227 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(81548..83227) Escherichia coli UMN026 7154611 YP_002410851.1 CDS leuD NC_011751.1 83534 84139 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(83534..84139) Escherichia coli UMN026 7157922 YP_002410852.1 CDS leuC NC_011751.1 84150 85550 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(84150..85550) Escherichia coli UMN026 7156945 YP_002410853.1 CDS leuB NC_011751.1 85553 86644 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(85553..86644) Escherichia coli UMN026 7156944 YP_002410854.1 CDS leuA NC_011751.1 86644 88215 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(86644..88215) Escherichia coli UMN026 7156943 YP_002410855.1 CDS leuL NC_011751.1 88308 88394 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(88308..88394) Escherichia coli UMN026 7156942 YP_002410856.1 CDS leuO NC_011751.1 89053 89997 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 89053..89997 Escherichia coli UMN026 7156946 YP_002410857.1 CDS ilvI NC_011751.1 90315 92039 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 90315..92039 Escherichia coli UMN026 7156947 YP_002410858.1 CDS ilvH NC_011751.1 92042 92533 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 92042..92533 Escherichia coli UMN026 7156804 YP_002410859.1 CDS fruR NC_011751.1 92713 93717 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 92713..93717 Escherichia coli UMN026 7156803 YP_002410860.1 CDS mraZ NC_011751.1 94319 94777 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 94319..94777 Escherichia coli UMN026 7156448 YP_002410861.1 CDS mraW NC_011751.1 94779 95720 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042184, 10493123, 2187182, 6350821; Product type e : enzyme; S-adenosyl-methyltransferase MraW 94779..95720 Escherichia coli UMN026 7157174 YP_002410862.1 CDS ftsL NC_011751.1 95717 96082 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 95717..96082 Escherichia coli UMN026 7157172 YP_002410863.1 CDS ftsI NC_011751.1 96098 97864 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91072213, 92202178, 94095121, 9603865, 9614966, 1332942, 1447153, 2198024, 2677607, 2681146, 3049550, 3911028, 6350821; Product type e : enzyme; septal peptidoglycan synthesis transpeptidase 96098..97864 Escherichia coli UMN026 7156462 YP_002410864.1 CDS murE NC_011751.1 97851 99338 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 97851..99338 Escherichia coli UMN026 7156460 YP_002410865.1 CDS murF NC_011751.1 99335 100693 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88273095, 90248455, 91310568, 97128642, 11090285, 2668880, 9166795; Product type e : enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 99335..100693 Escherichia coli UMN026 7157205 YP_002410866.1 CDS mraY NC_011751.1 100687 101769 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 100687..101769 Escherichia coli UMN026 7157206 YP_002410867.1 CDS murD NC_011751.1 101772 103088 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 101772..103088 Escherichia coli UMN026 7157173 YP_002410868.1 CDS ftsW NC_011751.1 103088 104332 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 103088..104332 Escherichia coli UMN026 7157204 YP_002410869.1 CDS murG NC_011751.1 104329 105396 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 104329..105396 Escherichia coli UMN026 7156465 YP_002410870.1 CDS murC NC_011751.1 105450 106925 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 105450..106925 Escherichia coli UMN026 7157207 YP_002410871.1 CDS ddl NC_011751.1 106918 107838 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 106918..107838 Escherichia coli UMN026 7157203 YP_002410872.1 CDS ftsQ NC_011751.1 107840 108670 D involved in septum formation; cell division protein FtsQ 107840..108670 Escherichia coli UMN026 7156126 YP_002410873.1 CDS ftsA NC_011751.1 108667 109929 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 108667..109929 Escherichia coli UMN026 7156464 YP_002410874.1 CDS ftsZ NC_011751.1 109990 111141 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 109990..111141 Escherichia coli UMN026 7156456 YP_002410875.1 CDS lpxC NC_011751.1 111242 112159 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 111242..112159 Escherichia coli UMN026 7156468 YP_002410876.1 CDS secM NC_011751.1 112390 112902 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 112390..112902 Escherichia coli UMN026 7157011 YP_002410877.1 CDS secA NC_011751.1 112964 115669 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 112964..115669 Escherichia coli UMN026 7157891 YP_002410878.1 CDS mutT NC_011751.1 115729 116127 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10218109, 89264540, 90136514, 91225007, 97444511, 1309939, 2841285, 3033442, 3288626, 7578113, 9063868; Product type e : enzyme; nucleoside triphosphate pyrophosphohydrolase 115729..116127 Escherichia coli UMN026 7157885 YP_002410879.1 CDS yacF NC_011751.1 116422 117165 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(116422..117165) Escherichia coli UMN026 7157215 YP_002410880.1 CDS coaE NC_011751.1 117165 117785 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(117165..117785) Escherichia coli UMN026 7158267 YP_002410881.1 CDS guaC NC_011751.1 118010 119053 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 118010..119053 Escherichia coli UMN026 7155990 YP_002410882.1 CDS hofC NC_011751.1 119088 120290 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96099298, 2904262, 7959070; Product type s : structure; type IV pilin biogenesis protein complement(119088..120290) Escherichia coli UMN026 7156624 YP_002410883.1 CDS hofB NC_011751.1 120280 121665 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96099298, 7959070; Product type pt : putative transporter; hypothetical protein complement(120280..121665) Escherichia coli UMN026 7156692 YP_002410884.1 CDS ppdD NC_011751.1 121675 122115 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20100782, 20271862, 96099298, 7959070; Product type ps : putative structure; putative major pilin subunit complement(121675..122115) Escherichia coli UMN026 7156691 YP_002410885.1 CDS nadC NC_011751.1 122318 123211 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(122318..123211) Escherichia coli UMN026 7157502 YP_002410886.1 CDS ampD NC_011751.1 123299 123850 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90113890, 95047240, 2607970, 7959070; Product type e : enzyme; N-acetyl-anhydromuranmyl-L-alanine amidase 123299..123850 Escherichia coli UMN026 7157223 YP_002410887.1 CDS ampE NC_011751.1 123847 124701 D involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE 123847..124701 Escherichia coli UMN026 7155738 YP_002410888.1 CDS aroP NC_011751.1 124744 126117 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1104763, 90174991, 9150230; Product type t : transporter; aromatic amino acid transporter complement(124744..126117) Escherichia coli UMN026 7155739 YP_002410889.1 CDS pdhR NC_011751.1 126658 127422 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 126658..127422 Escherichia coli UMN026 7155794 YP_002410890.1 CDS aceE NC_011751.1 127583 130246 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 127583..130246 Escherichia coli UMN026 7158097 YP_002410891.1 CDS aceF NC_011751.1 130261 132153 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 130261..132153 Escherichia coli UMN026 7155677 YP_002410892.1 CDS lpd NC_011751.1 132361 133785 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 132361..133785 Escherichia coli UMN026 7155678 YP_002410893.1 CDS yacH NC_011751.1 133856 135709 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(133856..135709) Escherichia coli UMN026 7157001 YP_002410894.1 CDS acnB NC_011751.1 136064 138661 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 136064..138661 Escherichia coli UMN026 7158268 YP_002410895.1 CDS yacL NC_011751.1 138858 139220 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401, 7567469; hypothetical protein 138858..139220 Escherichia coli UMN026 7155682 YP_002410896.1 CDS speD NC_011751.1 139258 140052 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(139258..140052) Escherichia coli UMN026 7158269 YP_002410897.1 CDS speE NC_011751.1 140068 140934 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(140068..140934) Escherichia coli UMN026 7157960 YP_002410898.1 CDS yacC NC_011751.1 141040 141558 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401; hypothetical protein complement(141040..141558) Escherichia coli UMN026 7157961 YP_002410899.1 CDS cueO NC_011751.1 141553 143103 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 141553..143103 Escherichia coli UMN026 7158266 YP_002410900.1 CDS gcd NC_011751.1 143150 145540 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10359647, 11604400, 14612441, 91035240, 93123180, 93286127; Product type e : enzyme; glucose dehydrogenase complement(143150..145540) Escherichia coli UMN026 7156048 YP_002410901.1 CDS hpt NC_011751.1 145746 146282 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 13808016, 339828, 6787390, 6801015, 12070315; Product type e : enzyme; hypoxanthine phosphoribosyltransferase 145746..146282 Escherichia coli UMN026 7156517 YP_002410902.1 CDS can NC_011751.1 146323 146985 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(146323..146985) Escherichia coli UMN026 7156711 YP_002410903.1 CDS yadG NC_011751.1 147094 148020 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 147094..148020 Escherichia coli UMN026 7155917 YP_002410904.1 CDS yadH NC_011751.1 148017 148787 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10474187; Product type pt : putative transporter; putative ABC transporter membrane protein 148017..148787 Escherichia coli UMN026 7158273 YP_002410905.1 CDS yadI NC_011751.1 148892 149332 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative PTS Enzyme IIA 148892..149332 Escherichia coli UMN026 7158274 YP_002410906.1 CDS yadE NC_011751.1 149396 150625 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported polysaccharide deacetylase 149396..150625 Escherichia coli UMN026 7158275 YP_002410907.1 CDS panD NC_011751.1 150629 151009 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(150629..151009) Escherichia coli UMN026 7158272 YP_002410908.1 CDS yadD NC_011751.1 151283 152227 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11319082; Product type pe : putative enzyme; putative transposase 151283..152227 Escherichia coli UMN026 7157379 YP_002410909.1 CDS panC NC_011751.1 152593 153444 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(152593..153444) Escherichia coli UMN026 7158271 YP_002410910.1 CDS panB NC_011751.1 153456 154250 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(153456..154250) Escherichia coli UMN026 7157378 YP_002410911.1 CDS ECUMN_0133 NC_011751.1 154364 155614 R Evidence 4 : Homologs of previously reported genes of unknown function; putative fimbrial-like adhesin protein complement(154364..155614) Escherichia coli UMN026 7157377 YP_002410912.1 CDS ECUMN_0134 NC_011751.1 155666 156265 R Evidence 4 : Homologs of previously reported genes of unknown function; putative fimbrial protein complement(155666..156265) Escherichia coli UMN026 7154612 YP_002410913.1 CDS ECUMN_0135 NC_011751.1 156279 156839 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(156279..156839) Escherichia coli UMN026 7154613 YP_002410914.1 CDS ECUMN_0136 NC_011751.1 156858 159533 R similar to the fimbrial usher protein PapC; putative outer membrane usher protein complement(156858..159533) Escherichia coli UMN026 7154614 YP_002410915.1 CDS ECUMN_0137 NC_011751.1 159493 160224 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8102362, 8202364, 9278503; Product type f : factor; putative chaperone protein EcpD complement(159493..160224) Escherichia coli UMN026 7154615 YP_002410916.1 CDS ECUMN_0138 NC_011751.1 160317 160913 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(160317..160913) Escherichia coli UMN026 7154616 YP_002410917.1 CDS folK NC_011751.1 161238 161717 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase complement(161238..161717) Escherichia coli UMN026 7154617 YP_002410918.1 CDS pcnB NC_011751.1 161714 163132 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I complement(161714..163132) Escherichia coli UMN026 7156428 YP_002410919.1 CDS yadB NC_011751.1 163171 164097 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA (Asp) synthetase complement(163171..164097) Escherichia coli UMN026 7157398 YP_002410920.1 CDS dksA NC_011751.1 164134 164589 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294157, 90202727, 2013578, 9298646, 9600841; Product type r : regulator; RNA polymerase-binding transcription factor complement(164134..164589) Escherichia coli UMN026 7158270 YP_002410921.1 CDS sfsA NC_011751.1 164767 165471 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(164767..165471) Escherichia coli UMN026 7156177 YP_002410922.1 CDS ligT NC_011751.1 165486 166016 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97094878; Product type e : enzyme; 2'-5' RNA ligase complement(165486..166016) Escherichia coli UMN026 7157909 YP_002410923.1 CDS hrpB NC_011751.1 166090 168519 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 166090..168519 Escherichia coli UMN026 7156981 YP_002410924.1 CDS mrcB NC_011751.1 168613 171147 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 168613..171147 Escherichia coli UMN026 7156713 YP_002410925.1 CDS fhuA NC_011751.1 171367 173625 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 171367..173625 Escherichia coli UMN026 7157176 YP_002410926.1 CDS fhuC NC_011751.1 173676 174473 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 173676..174473 Escherichia coli UMN026 7156344 YP_002410927.1 CDS fhuD NC_011751.1 174473 175363 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 174473..175363 Escherichia coli UMN026 7156346 YP_002410928.1 CDS fhuB NC_011751.1 175360 177342 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate permease 175360..177342 Escherichia coli UMN026 7156347 YP_002410929.1 CDS hemL NC_011751.1 177377 178657 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(177377..178657) Escherichia coli UMN026 7156345 YP_002410930.1 CDS clcA NC_011751.1 178882 180303 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 178882..180303 Escherichia coli UMN026 7156658 YP_002410931.1 CDS yadR NC_011751.1 180385 180729 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 180385..180729 Escherichia coli UMN026 7155975 YP_002410932.1 CDS yadS NC_011751.1 180776 181399 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(180776..181399) Escherichia coli UMN026 7158276 YP_002410933.1 CDS btuF NC_011751.1 181437 182237 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(181437..182237) Escherichia coli UMN026 7158277 YP_002410934.1 CDS pfs NC_011751.1 182230 182928 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(182230..182928) Escherichia coli UMN026 7155898 YP_002410935.1 CDS dgt NC_011751.1 183012 184529 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 183012..184529 Escherichia coli UMN026 7157425 YP_002410936.1 CDS degP NC_011751.1 184659 186083 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 184659..186083 Escherichia coli UMN026 7156155 YP_002410937.1 CDS cdaR NC_011751.1 186238 187395 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 186238..187395 Escherichia coli UMN026 7156137 YP_002410938.1 CDS yaeH NC_011751.1 187449 187835 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(187449..187835) Escherichia coli UMN026 7155936 YP_002410939.1 CDS dapD NC_011751.1 188148 188972 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(188148..188972) Escherichia coli UMN026 7158280 YP_002410940.1 CDS glnD NC_011751.1 189003 191675 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(189003..191675) Escherichia coli UMN026 7156109 YP_002410941.1 CDS map NC_011751.1 191737 192531 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(191737..192531) Escherichia coli UMN026 7156550 YP_002410942.1 CDS rpsB NC_011751.1 192899 193624 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 192899..193624 Escherichia coli UMN026 7158016 YP_002410943.1 CDS tsf NC_011751.1 193882 194733 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 193882..194733 Escherichia coli UMN026 7157768 YP_002410944.1 CDS pyrH NC_011751.1 194880 195605 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 194880..195605 Escherichia coli UMN026 7158132 YP_002410945.1 CDS frr NC_011751.1 195897 196454 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 195897..196454 Escherichia coli UMN026 7157603 YP_002410946.1 CDS dxr NC_011751.1 196546 197742 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 196546..197742 Escherichia coli UMN026 7156443 YP_002410947.1 CDS ispU NC_011751.1 197928 198689 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 197928..198689 Escherichia coli UMN026 7156215 YP_002410948.1 CDS cdsA NC_011751.1 198702 199559 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 198702..199559 Escherichia coli UMN026 7156869 YP_002410949.1 CDS yaeL NC_011751.1 199571 200923 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 199571..200923 Escherichia coli UMN026 7155939 YP_002410950.1 CDS yaeT NC_011751.1 200953 203385 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 200953..203385 Escherichia coli UMN026 7158282 YP_002410951.1 CDS hlpA NC_011751.1 203507 203992 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15101556, 90201355, 97032152, 99386928, 1987124, 2843433, 9298646, 2167239; Product type f : factor; periplasmic chaperone 203507..203992 Escherichia coli UMN026 7158286 YP_002410952.1 CDS lpxD NC_011751.1 203996 205021 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 203996..205021 Escherichia coli UMN026 7156687 YP_002410953.1 CDS fabZ NC_011751.1 205126 205581 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 205126..205581 Escherichia coli UMN026 7157012 YP_002410954.1 CDS lpxA NC_011751.1 205585 206373 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 205585..206373 Escherichia coli UMN026 7156301 YP_002410955.1 CDS lpxB NC_011751.1 206373 207521 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 206373..207521 Escherichia coli UMN026 7157009 YP_002410956.1 CDS rnhB NC_011751.1 207518 208114 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 207518..208114 Escherichia coli UMN026 7157010 YP_002410957.1 CDS dnaE NC_011751.1 208151 211633 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 208151..211633 Escherichia coli UMN026 7157714 YP_002410958.1 CDS accA NC_011751.1 211646 212605 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 211646..212605 Escherichia coli UMN026 7156186 YP_002410959.1 CDS ldcC NC_011751.1 212704 214845 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97480927, 98195734, 98357244, 9226257, 9723924; Product type e : enzyme; lysine decarboxylase 2, constitutive 212704..214845 Escherichia coli UMN026 7155671 YP_002410960.1 CDS yaeR NC_011751.1 214902 215291 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 214902..215291 Escherichia coli UMN026 7156936 YP_002410961.1 CDS tilS NC_011751.1 215356 216651 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA (Ile)-lysidine synthetase 215356..216651 Escherichia coli UMN026 7158285 YP_002410962.1 CDS rof NC_011751.1 216700 216954 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(216700..216954) Escherichia coli UMN026 7158072 YP_002410963.1 CDS yaeP NC_011751.1 216947 217147 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(216947..217147) Escherichia coli UMN026 7157721 YP_002410964.1 CDS yaeQ NC_011751.1 217313 217858 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 217313..217858 Escherichia coli UMN026 7158283 YP_002410965.1 CDS yaeJ NC_011751.1 217855 218277 D Evidence 4 : Homologs of previously reported genes of unknown function; peptidyl-tRNA hydrolase domain protein 217855..218277 Escherichia coli UMN026 7158284 YP_002410966.1 CDS nlpE NC_011751.1 218291 219001 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11830644, 95362641, 95362642; Product type lp : lipoprotein; lipoprotein involved with copper homeostasis and adhesion 218291..219001 Escherichia coli UMN026 7158281 YP_002410967.1 CDS yaeF NC_011751.1 219031 219855 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein complement(219031..219855) Escherichia coli UMN026 7157289 YP_002410968.1 CDS proS NC_011751.1 219908 221626 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(219908..221626) Escherichia coli UMN026 7158279 YP_002410969.1 CDS yaeB NC_011751.1 221737 222444 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(221737..222444) Escherichia coli UMN026 7157535 YP_002410970.1 CDS rcsF NC_011751.1 222441 222845 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93094132; Product type pr : putative regulator; outer membrane lipoprotein complement(222441..222845) Escherichia coli UMN026 7158278 YP_002410971.1 CDS metQ NC_011751.1 222963 223778 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12169620, 12218041, 12819857, 1459951; Product type t : transporter; DL-methionine transporter substrate-binding subunit complement(222963..223778) Escherichia coli UMN026 7157632 YP_002410972.1 CDS metI NC_011751.1 223818 224471 R part of the MetNIQ methionine uptake system; DL-methionine permease complement(223818..224471) Escherichia coli UMN026 7157112 YP_002410973.1 CDS metN NC_011751.1 224464 225495 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(224464..225495) Escherichia coli UMN026 7157107 YP_002410974.1 CDS gmhB NC_011751.1 225683 226255 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 225683..226255 Escherichia coli UMN026 7157111 YP_002410975.1 CDS dkgB NC_011751.1 232018 232821 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 232018..232821 Escherichia coli UMN026 7155587 YP_002410976.1 CDS yafC NC_011751.1 232818 233732 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(232818..233732) Escherichia coli UMN026 7156176 YP_002410977.1 CDS yafD NC_011751.1 233973 234773 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1663890; hypothetical protein 233973..234773 Escherichia coli UMN026 7158287 YP_002410978.1 CDS yafE NC_011751.1 234850 235620 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase 234850..235620 Escherichia coli UMN026 7158288 YP_002410979.1 CDS mltD NC_011751.1 235668 237026 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(235668..237026) Escherichia coli UMN026 7158289 YP_002410980.1 CDS gloB NC_011751.1 237098 237853 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(237098..237853) Escherichia coli UMN026 7157142 YP_002410981.1 CDS yafS NC_011751.1 237887 238609 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase 237887..238609 Escherichia coli UMN026 7156560 YP_002410982.1 CDS rnhA NC_011751.1 238606 239073 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(238606..239073) Escherichia coli UMN026 7158298 YP_002410983.1 CDS dnaQ NC_011751.1 239138 239869 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 239138..239869 Escherichia coli UMN026 7157713 YP_002410984.1 CDS yafT NC_011751.1 240405 241190 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aminopeptidase 240405..241190 Escherichia coli UMN026 7155598 YP_002410985.1 CDS ECUMN_0214 NC_011751.1 241530 242009 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(241530..242009) Escherichia coli UMN026 7158299 YP_002410986.1 CDS ECUMN_0215 NC_011751.1 242027 243526 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(242027..243526) Escherichia coli UMN026 7154618 YP_002410987.1 CDS ECUMN_0216 NC_011751.1 243396 246923 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein complement(243396..246923) Escherichia coli UMN026 7154619 YP_002410988.1 CDS ECUMN_0217 NC_011751.1 246943 248451 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(246943..248451) Escherichia coli UMN026 7154620 YP_002410989.1 CDS ECUMN_0218 NC_011751.1 248390 249133 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(248390..249133) Escherichia coli UMN026 7154621 YP_002410990.1 CDS ECUMN_0219 NC_011751.1 249130 251862 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity complement(249130..251862) Escherichia coli UMN026 7154622 YP_002410991.1 CDS ECUMN_0220 NC_011751.1 251872 252645 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein complement(251872..252645) Escherichia coli UMN026 7154623 YP_002410992.1 CDS ECUMN_0221 NC_011751.1 252650 253996 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(252650..253996) Escherichia coli UMN026 7154624 YP_002410993.1 CDS ECUMN_0222 NC_011751.1 253999 254523 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(253999..254523) Escherichia coli UMN026 7154625 YP_002410994.1 CDS ECUMN_0223 NC_011751.1 254520 255908 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(254520..255908) Escherichia coli UMN026 7154626 YP_002410995.1 CDS ECUMN_0224 NC_011751.1 255817 256866 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(255817..256866) Escherichia coli UMN026 7154627 YP_002410996.1 CDS ECUMN_0225 NC_011751.1 256830 258689 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(256830..258689) Escherichia coli UMN026 7154628 YP_002410997.1 CDS ECUMN_0226 NC_011751.1 258677 259102 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(258677..259102) Escherichia coli UMN026 7154629 YP_002410998.1 CDS ECUMN_0227 NC_011751.1 259107 260591 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(259107..260591) Escherichia coli UMN026 7154630 YP_002410999.1 CDS ECUMN_0228 NC_011751.1 260614 261117 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(260614..261117) Escherichia coli UMN026 7154631 YP_002411000.1 CDS ECUMN_0229 NC_011751.1 261820 262338 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 261820..262338 Escherichia coli UMN026 7154632 YP_002411001.1 CDS ECUMN_0230 NC_011751.1 262559 264517 D Evidence 4 : Homologs of previously reported genes of unknown function; putative VgrG/E protein 262559..264517 Escherichia coli UMN026 7154633 YP_002411002.1 CDS ECUMN_0231 NC_011751.1 264514 265356 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 264514..265356 Escherichia coli UMN026 7154634 YP_002411003.1 CDS ECUMN_0232 NC_011751.1 265378 266949 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 265378..266949 Escherichia coli UMN026 7154635 YP_002411004.1 CDS ECUMN_0233 NC_011751.1 267016 268026 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 267016..268026 Escherichia coli UMN026 7154636 YP_002411005.1 CDS yhhI NC_011751.1 268336 269295 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ph : phenotype; putative transposase 268336..269295 Escherichia coli UMN026 7154637 YP_002411006.1 CDS ECUMN_0235 NC_011751.1 269323 269463 R Evidence 6 : Doubtful CDS; hypothetical protein complement(269323..269463) Escherichia coli UMN026 7159174 YP_002411007.1 CDS ECUMN_0236 NC_011751.1 269827 271077 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative reverse transcriptase 269827..271077 Escherichia coli UMN026 7154638 YP_002411008.1 CDS yhhI NC_011751.1 271524 272660 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ph : phenotype; putative transposase 271524..272660 Escherichia coli UMN026 7154639 YP_002411009.1 CDS ECUMN_0238 NC_011751.1 272780 273283 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 272780..273283 Escherichia coli UMN026 7159175 YP_002411010.1 CDS ECUMN_0239 NC_011751.1 273350 273862 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 273350..273862 Escherichia coli UMN026 7154640 YP_002411011.1 CDS yafV NC_011751.1 274134 274904 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8526497; Product type pe : putative enzyme; hypothetical protein complement(274134..274904) Escherichia coli UMN026 7154641 YP_002411012.1 CDS ivy NC_011751.1 275058 275531 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 275058..275531 Escherichia coli UMN026 7158300 YP_002411013.1 CDS fadE NC_011751.1 275574 278018 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(275574..278018) Escherichia coli UMN026 7156880 YP_002411014.1 CDS gmhA NC_011751.1 278258 278836 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 278258..278836 Escherichia coli UMN026 7156305 YP_002411015.1 CDS yafJ NC_011751.1 279042 279809 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutamine amidotransferases class-II 279042..279809 Escherichia coli UMN026 7157000 YP_002411016.1 CDS yafK NC_011751.1 279780 280520 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(279780..280520) Escherichia coli UMN026 7158290 YP_002411017.1 CDS yafL NC_011751.1 280812 281570 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported hydrolase 280812..281570 Escherichia coli UMN026 7158291 YP_002411018.1 CDS yafM NC_011751.1 281747 282244 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 281747..282244 Escherichia coli UMN026 7158292 YP_002411019.1 CDS ECUMN_0248 NC_011751.1 282403 283449 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family complement(282403..283449) Escherichia coli UMN026 7158293 YP_002411020.1 CDS ECUMN_0249 NC_011751.1 283269 283616 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS3 family complement(283269..283616) Escherichia coli UMN026 7154642 YP_002411021.1 CDS fhiA NC_011751.1 283944 286037 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7783646, 15687208; Product type s : structure; flagellar system protein complement(283944..286037) Escherichia coli UMN026 7154643 YP_002411022.1 CDS flhB NC_011751.1 286021 287160 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(286021..287160) Escherichia coli UMN026 7156342 YP_002411023.1 CDS lfiR NC_011751.1 287150 287932 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type pt : putative transporter; Flagellar biosynthetic protein fliR complement(287150..287932) Escherichia coli UMN026 7156964 YP_002411024.1 CDS lfiQ NC_011751.1 287934 288206 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar export/assembly FliQ-like protein complement(287934..288206) Escherichia coli UMN026 7156974 YP_002411025.1 CDS fliP NC_011751.1 288209 288961 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(288209..288961) Escherichia coli UMN026 7156973 YP_002411026.1 CDS lfiN NC_011751.1 288958 289329 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type cp : cell process; lateral flagellar motor switch C ring FliN-like protein complement(288958..289329) Escherichia coli UMN026 7156972 YP_002411027.1 CDS lfiM NC_011751.1 289322 290173 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type cp : cell process; lateral flagellar motor switch C-ring FliM-like protein complement(289322..290173) Escherichia coli UMN026 7156971 YP_002411028.1 CDS lafK NC_011751.1 290561 291541 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type r : regulator; lateral flagellar RpoN-interacting regulatory protein 290561..291541 Escherichia coli UMN026 7156970 YP_002411029.1 CDS lfiE NC_011751.1 291556 291897 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar basal body component FliE-like protein 291556..291897 Escherichia coli UMN026 7156929 YP_002411030.1 CDS fliF NC_011751.1 291902 293548 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar MS-ring protein 291902..293548 Escherichia coli UMN026 7156965 YP_002411031.1 CDS fliG NC_011751.1 293526 294536 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 293526..294536 Escherichia coli UMN026 7156966 YP_002411032.1 CDS fliH NC_011751.1 294539 295249 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 294539..295249 Escherichia coli UMN026 7156967 YP_002411033.1 CDS lgiI NC_011751.1 295242 296579 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type e : enzyme; lateral flagellar export/assembly protein 295242..296579 Escherichia coli UMN026 7156968 YP_002411034.1 CDS lfiJ NC_011751.1 296582 297016 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar export/assembly LfiJ-like protein 296582..297016 Escherichia coli UMN026 7156976 YP_002411035.1 CDS ECUMN_0264 NC_011751.1 297019 297423 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11882717, 1906926, 8393871, 9182537, 11487587, 10508782, 15687208; Product type e : enzyme; glycerol-3-phosphate cytidylyltransferase 297019..297423 Escherichia coli UMN026 7156969 YP_002411036.1 CDS ECUMN_0265 NC_011751.1 297567 300110 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type pe : putative enzyme; putative glysosyltransferase complement(297567..300110) Escherichia coli UMN026 7154644 YP_002411037.1 CDS lafV NC_011751.1 300217 301185 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type pe : putative enzyme; putative lysine-N-methylase complement(300217..301185) Escherichia coli UMN026 7154645 YP_002411038.1 CDS lfgN NC_011751.1 301273 301701 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type f : factor; lateral flagellar chaperone FlgN-like protein complement(301273..301701) Escherichia coli UMN026 7156931 YP_002411039.1 CDS lfgM NC_011751.1 301714 301992 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type r : regulator; lateral flagellar anti-sigma factor 28 FlgM-like protein complement(301714..301992) Escherichia coli UMN026 7156963 YP_002411040.1 CDS lfgA NC_011751.1 302073 302810 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar P-ring addition FlgA-like protein complement(302073..302810) Escherichia coli UMN026 7156962 YP_002411041.1 CDS lfgB NC_011751.1 302862 303227 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2129540, 15687208; Product type s : structure; lateral flagellar rod FlgB-like protein 302862..303227 Escherichia coli UMN026 7156951 YP_002411042.1 CDS flgC NC_011751.1 303230 303661 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar basal body rod protein FlgC 303230..303661 Escherichia coli UMN026 7156952 YP_002411043.1 CDS lfdD NC_011751.1 303661 304374 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar rod FlgD-like protein 303661..304374 Escherichia coli UMN026 7156953 YP_002411044.1 CDS lfgE NC_011751.1 304518 305720 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook FlgE-like protein 304518..305720 Escherichia coli UMN026 7156950 YP_002411045.1 CDS flgF NC_011751.1 305720 306457 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 305720..306457 Escherichia coli UMN026 7156954 YP_002411046.1 CDS flgG NC_011751.1 306510 307421 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 306510..307421 Escherichia coli UMN026 7156955 YP_002411047.1 CDS flgH NC_011751.1 307628 308293 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH; flagellar basal body L-ring protein 307628..308293 Escherichia coli UMN026 7156956 YP_002411048.1 CDS flgI NC_011751.1 308293 309408 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 308293..309408 Escherichia coli UMN026 7156957 YP_002411049.1 CDS lfgJ NC_011751.1 309408 309707 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type e : enzyme; lateral flagellar peptidoglycan hydrolase FlgJ-like protein 309408..309707 Escherichia coli UMN026 7156958 YP_002411050.1 CDS lfgK NC_011751.1 309883 311259 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook associated FlgK-like protein 309883..311259 Escherichia coli UMN026 7156959 YP_002411051.1 CDS lfgL NC_011751.1 311274 312203 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook associated FlgL-like protein 311274..312203 Escherichia coli UMN026 7156960 YP_002411052.1 CDS lafW NC_011751.1 312220 313197 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type s : structure; putative lateral flagellar hook associated protein 312220..313197 Escherichia coli UMN026 7156961 YP_002411053.1 CDS ECUMN_0282 NC_011751.1 313270 313614 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15687208; hypothetical protein 313270..313614 Escherichia coli UMN026 7156932 YP_002411054.1 CDS ECUMN_0283 NC_011751.1 313624 313923 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type pr : putative regulator; transcriptional regulator 313624..313923 Escherichia coli UMN026 7154646 YP_002411055.1 CDS lafZ NC_011751.1 313981 314874 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type r : regulator; lateral flagellar transmembrane regulator complement(313981..314874) Escherichia coli UMN026 7154647 YP_002411056.1 CDS lafA NC_011751.1 315243 316223 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellin FliC-like protein 315243..316223 Escherichia coli UMN026 7156933 YP_002411057.1 CDS lafB NC_011751.1 316428 317744 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook associated FliD-like protein 316428..317744 Escherichia coli UMN026 7156923 YP_002411058.1 CDS lafC NC_011751.1 317767 318159 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type f : factor; lateral flagellar chaperone FliS-like protein 317767..318159 Escherichia coli UMN026 7156924 YP_002411059.1 CDS lafD NC_011751.1 318164 318475 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type f : factor; lateral flagellar chaperone FliT-like protein 318164..318475 Escherichia coli UMN026 7156925 YP_002411060.1 CDS lafE NC_011751.1 318472 319530 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook length control FliK-like protein 318472..319530 Escherichia coli UMN026 7156926 YP_002411061.1 CDS lafF NC_011751.1 319538 320005 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type s : structure; lateral flagellar associated FliL-like protein 319538..320005 Escherichia coli UMN026 7156927 YP_002411062.1 CDS ECUMN_0291 NC_011751.1 320025 320741 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 320025..320741 Escherichia coli UMN026 7156928 YP_002411063.1 CDS lafT NC_011751.1 320754 321617 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 320754..321617 Escherichia coli UMN026 7154648 YP_002411064.1 CDS mbhA NC_011751.1 321620 322543 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; hypothetical protein 321620..322543 Escherichia coli UMN026 7156930 YP_002411065.1 CDS dinB NC_011751.1 322614 323669 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 322614..323669 Escherichia coli UMN026 7157065 YP_002411066.1 CDS yafN NC_011751.1 323721 324014 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093, 14594833; Product type pf : putative factor; putative antitoxin of the YafO-YafN toxin-antitoxin system 323721..324014 Escherichia coli UMN026 7156166 YP_002411067.1 CDS yafP NC_011751.1 324425 324877 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093; Product type pe : putative enzyme; hypothetical protein 324425..324877 Escherichia coli UMN026 7158296 YP_002411068.1 CDS ECUMN_0299 NC_011751.1 325056 326207 D mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 325056..326207 Escherichia coli UMN026 7158297 YP_002411069.1 CDS prfH NC_011751.1 326318 326818 D similar to release factor 1 and 2; peptide chain release factor-like protein 326318..326818 Escherichia coli UMN026 7154649 YP_002411070.1 CDS ECUMN_0301 NC_011751.1 326826 327389 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 326826..327389 Escherichia coli UMN026 7157520 YP_002411071.1 CDS ECUMN_0302 NC_011751.1 327406 327687 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(327406..327687) Escherichia coli UMN026 7154650 YP_002411072.1 CDS pepD NC_011751.1 327696 329153 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1695895, 21101837, 88121730, 92204123, 2651887; Product type e : enzyme; aminoacyl-histidine dipeptidase complement(327696..329153) Escherichia coli UMN026 7154651 YP_002411073.1 CDS gpt NC_011751.1 329414 329872 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 329414..329872 Escherichia coli UMN026 7157412 YP_002411074.1 CDS frsA NC_011751.1 329964 331208 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 329964..331208 Escherichia coli UMN026 7156608 YP_002411075.1 CDS crl NC_011751.1 331266 331667 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 331266..331667 Escherichia coli UMN026 7156444 YP_002411076.1 CDS phoE NC_011751.1 331706 332761 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89178658, 89380253, 92219258, 98090453, 1380671, 1848301, 1848682, 6089111, 6341601, 7679770; Product type t : transporter; outer membrane phosphoporin protein E complement(331706..332761) Escherichia coli UMN026 7156014 YP_002411077.1 CDS proB NC_011751.1 333049 334152 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 333049..334152 Escherichia coli UMN026 7157457 YP_002411078.1 CDS proA NC_011751.1 334164 335417 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 334164..335417 Escherichia coli UMN026 7157531 YP_002411079.1 CDS ECUMN_0311 NC_011751.1 336526 337410 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-like transcriptional regulator complement(336526..337410) Escherichia coli UMN026 7158301 YP_002411080.1 CDS ECUMN_0312 NC_011751.1 337576 338733 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 337576..338733 Escherichia coli UMN026 7154652 YP_002411081.1 CDS opdE NC_011751.1 338809 340002 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1427017; Product type r : regulator; transcription regulatory protein opdE 338809..340002 Escherichia coli UMN026 7154653 YP_002411082.1 CDS yagQ NC_011751.1 340183 341139 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(340183..341139) Escherichia coli UMN026 7157356 YP_002411083.1 CDS yagR NC_011751.1 341149 343347 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(341149..343347) Escherichia coli UMN026 7158302 YP_002411084.1 CDS yagS NC_011751.1 343344 344300 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(343344..344300) Escherichia coli UMN026 7158303 YP_002411085.1 CDS ECUMN_0318 NC_011751.1 344825 345172 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS3 family 344825..345172 Escherichia coli UMN026 7158305 YP_002411086.1 CDS ECUMN_0319 NC_011751.1 344992 346038 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family 344992..346038 Escherichia coli UMN026 7154654 YP_002411087.1 CDS yagU NC_011751.1 346654 347268 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 346654..347268 Escherichia coli UMN026 7158306 YP_002411088.1 CDS yagV NC_011751.1 348160 348870 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(348160..348870) Escherichia coli UMN026 7158307 YP_002411089.1 CDS yagW NC_011751.1 348839 350482 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative surface or exported protein complement(348839..350482) Escherichia coli UMN026 7158308 YP_002411090.1 CDS yagX NC_011751.1 350472 352997 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(350472..352997) Escherichia coli UMN026 7158309 YP_002411091.1 CDS yagY NC_011751.1 353023 353691 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(353023..353691) Escherichia coli UMN026 7158310 YP_002411092.1 CDS ecpA NC_011751.1 353749 354336 R Evidence 2b : Function of strongly homologous gene; PubMedId : 17563352, 11466275; Product type s : structure; common pilus ECP complement(353749..354336) Escherichia coli UMN026 7158311 YP_002411093.1 CDS ykgK NC_011751.1 354411 355001 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(354411..355001) Escherichia coli UMN026 7156225 YP_002411094.1 CDS rpmE2 NC_011751.1 356178 356441 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B complement(356178..356441) Escherichia coli UMN026 7159455 YP_002411095.1 CDS ECUMN_0330 NC_011751.1 356495 356728 R Evidence 6 : Doubtful CDS; hypothetical protein complement(356495..356728) Escherichia coli UMN026 7159456 YP_002411096.1 CDS ECUMN_0331 NC_011751.1 357381 358523 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NADH-dependent flavin oxidoreductase complement(357381..358523) Escherichia coli UMN026 7154656 YP_002411097.1 CDS ECUMN_0332 NC_011751.1 358768 359688 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(358768..359688) Escherichia coli UMN026 7154657 YP_002411098.1 CDS ECUMN_0333 NC_011751.1 359782 360771 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-like transcriptional regulator 359782..360771 Escherichia coli UMN026 7154658 YP_002411099.1 CDS ECUMN_0334 NC_011751.1 360954 361889 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR family transcriptional regulator 360954..361889 Escherichia coli UMN026 7154659 YP_002411100.1 CDS ECUMN_0335 NC_011751.1 361920 362909 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldo-keto reductase complement(361920..362909) Escherichia coli UMN026 7154660 YP_002411101.1 CDS ECUMN_0336 NC_011751.1 362936 363787 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17575004; Product type pe : putative enzyme; putative aldo-keto reductase complement(362936..363787) Escherichia coli UMN026 7154661 YP_002411102.1 CDS ECUMN_0337 NC_011751.1 364353 368606 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative adhesin 364353..368606 Escherichia coli UMN026 7154662 YP_002411103.1 CDS ykgA NC_011751.1 368727 369617 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator ykgA complement(368727..369617) Escherichia coli UMN026 7154663 YP_002411104.1 CDS ECUMN_0339 NC_011751.1 369817 370701 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative reductase 369817..370701 Escherichia coli UMN026 7159446 YP_002411105.1 CDS ykgB NC_011751.1 370861 371454 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(370861..371454) Escherichia coli UMN026 7154664 YP_002411106.1 CDS ykgI NC_011751.1 371466 371702 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(371466..371702) Escherichia coli UMN026 7159447 YP_002411107.1 CDS ykgC NC_011751.1 371811 373136 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(371811..373136) Escherichia coli UMN026 7159454 YP_002411108.1 CDS ykgD NC_011751.1 373363 374217 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative AraC-type DNA-binding transcriptional regulator 373363..374217 Escherichia coli UMN026 7159448 YP_002411109.1 CDS ykgE NC_011751.1 374745 375464 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydroxyacid oxidoreductase (Fe-S centre) 374745..375464 Escherichia coli UMN026 7159449 YP_002411110.1 CDS ykgF NC_011751.1 375475 376902 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 375475..376902 Escherichia coli UMN026 7159450 YP_002411111.1 CDS ykgG NC_011751.1 376895 377590 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 376895..377590 Escherichia coli UMN026 7159451 YP_002411112.1 CDS ECUMN_0347 NC_011751.1 377664 377861 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(377664..377861) Escherichia coli UMN026 7159452 YP_002411113.1 CDS ykgH NC_011751.1 377833 378501 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(377833..378501) Escherichia coli UMN026 7154665 YP_002411114.1 CDS betA NC_011751.1 378712 380382 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(378712..380382) Escherichia coli UMN026 7159453 YP_002411115.1 CDS betB NC_011751.1 380396 381868 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(380396..381868) Escherichia coli UMN026 7155867 YP_002411116.1 CDS betI NC_011751.1 381882 382469 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(381882..382469) Escherichia coli UMN026 7155868 YP_002411117.1 CDS betT NC_011751.1 382598 384631 D proton-motive-force-driven choline transporter; choline transport protein BetT 382598..384631 Escherichia coli UMN026 7155869 YP_002411118.1 CDS ECUMN_0353 NC_011751.1 385000 385188 R Evidence 6 : Doubtful CDS; hypothetical protein complement(385000..385188) Escherichia coli UMN026 7155870 YP_002411119.1 CDS yahA NC_011751.1 385508 386596 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995192; Product type e : enzyme; cyclic di-GMP phosphodiesterase 385508..386596 Escherichia coli UMN026 7154666 YP_002411120.1 CDS yahB NC_011751.1 386638 387570 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(386638..387570) Escherichia coli UMN026 7158312 YP_002411121.1 CDS yahC NC_011751.1 387662 388159 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(387662..388159) Escherichia coli UMN026 7158313 YP_002411122.1 CDS yahD NC_011751.1 388417 389022 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 388417..389022 Escherichia coli UMN026 7158314 YP_002411123.1 CDS yahE NC_011751.1 389062 389925 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 389062..389925 Escherichia coli UMN026 7158315 YP_002411124.1 CDS yahF NC_011751.1 389915 391462 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 389915..391462 Escherichia coli UMN026 7158316 YP_002411125.1 CDS yahG NC_011751.1 391462 392880 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 391462..392880 Escherichia coli UMN026 7158317 YP_002411126.1 CDS yahI NC_011751.1 392976 393926 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7711027, 11523892; Product type pe : putative enzyme; putative carbamate kinase 392976..393926 Escherichia coli UMN026 7158318 YP_002411127.1 CDS yahJ NC_011751.1 393936 395318 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; putative deaminase 393936..395318 Escherichia coli UMN026 7158319 YP_002411128.1 CDS ECUMN_0363 NC_011751.1 395580 396023 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 395580..396023 Escherichia coli UMN026 7158320 YP_002411129.1 CDS ECUMN_0364 NC_011751.1 396274 397260 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter periplasmic binding protein 396274..397260 Escherichia coli UMN026 7154667 YP_002411130.1 CDS ECUMN_0365 NC_011751.1 397294 398793 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar ABC transporter ATP-binding protein 397294..398793 Escherichia coli UMN026 7154668 YP_002411131.1 CDS ECUMN_0366 NC_011751.1 398786 399757 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative sugar ABC transporter permease 398786..399757 Escherichia coli UMN026 7154669 YP_002411132.1 CDS ECUMN_0367 NC_011751.1 399724 400710 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative sugar ABC transporter permease 399724..400710 Escherichia coli UMN026 7154670 YP_002411133.1 CDS yahK NC_011751.1 400797 401846 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 400797..401846 Escherichia coli UMN026 7154671 YP_002411134.1 CDS yahL NC_011751.1 402089 402904 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 402089..402904 Escherichia coli UMN026 7158321 YP_002411135.1 CDS yahM NC_011751.1 403317 403562 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 403317..403562 Escherichia coli UMN026 7155620 YP_002411136.1 CDS yahO NC_011751.1 404397 404672 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 404397..404672 Escherichia coli UMN026 7158325 YP_002411137.1 CDS prpR NC_011751.1 404773 406359 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9325432, 15805526; Product type r : regulator; DNA-binding transcriptional activator complement(404773..406359) Escherichia coli UMN026 7158326 YP_002411138.1 CDS prpB NC_011751.1 406598 407488 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 406598..407488 Escherichia coli UMN026 7157544 YP_002411139.1 CDS prpC NC_011751.1 408021 409190 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 408021..409190 Escherichia coli UMN026 7157540 YP_002411140.1 CDS prpD NC_011751.1 409224 410675 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 409224..410675 Escherichia coli UMN026 7157541 YP_002411141.1 CDS prpE NC_011751.1 410715 412601 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 410715..412601 Escherichia coli UMN026 7157542 YP_002411142.1 CDS codB NC_011751.1 413502 414761 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92349961; Product type t : transporter; cytosine permease 413502..414761 Escherichia coli UMN026 7157543 YP_002411143.1 CDS codA NC_011751.1 414751 416034 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 414751..416034 Escherichia coli UMN026 7155996 YP_002411144.1 CDS cynR NC_011751.1 416167 417066 R controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR complement(416167..417066) Escherichia coli UMN026 7155995 YP_002411145.1 CDS cynT NC_011751.1 417176 417835 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91242169, 92156106, 94075239, 3049588; Product type e : enzyme; carbonic anhydrase 417176..417835 Escherichia coli UMN026 7156069 YP_002411146.1 CDS cynS NC_011751.1 417866 418336 D catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 417866..418336 Escherichia coli UMN026 7156071 YP_002411147.1 CDS cynX NC_011751.1 418369 419523 D MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; putative cyanate transporter 418369..419523 Escherichia coli UMN026 7156070 YP_002411148.1 CDS lacA NC_011751.1 419611 420222 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(419611..420222) Escherichia coli UMN026 7156072 YP_002411149.1 CDS lacY NC_011751.1 420288 421541 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(420288..421541) Escherichia coli UMN026 7156919 YP_002411150.1 CDS lacZ NC_011751.1 421593 424667 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(421593..424667) Escherichia coli UMN026 7156921 YP_002411151.1 CDS lacI NC_011751.1 424790 425872 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(424790..425872) Escherichia coli UMN026 7156922 YP_002411152.1 CDS mhpR NC_011751.1 425949 426896 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR complement(425949..426896) Escherichia coli UMN026 7156920 YP_002411153.1 CDS mhpA NC_011751.1 426973 428637 D catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 426973..428637 Escherichia coli UMN026 7157126 YP_002411154.1 CDS mhpB NC_011751.1 428639 429583 D catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 428639..429583 Escherichia coli UMN026 7157120 YP_002411155.1 CDS mhpC NC_011751.1 429586 430467 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87008429, 94002258, 15663942; Product type e : enzyme; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 429586..430467 Escherichia coli UMN026 7157121 YP_002411156.1 CDS mhpD NC_011751.1 430477 431286 D catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 430477..431286 Escherichia coli UMN026 7157122 YP_002411157.1 CDS mhpF NC_011751.1 431283 432233 D catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 431283..432233 Escherichia coli UMN026 7157123 YP_002411158.1 CDS mhpE NC_011751.1 432230 433243 D catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 432230..433243 Escherichia coli UMN026 7157125 YP_002411159.1 CDS mhpT NC_011751.1 433419 434630 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7961399; Product type t : transporter; putative 3-hydroxyphenylpropionic transporter MhpT 433419..434630 Escherichia coli UMN026 7157124 YP_002411160.1 CDS yaiL NC_011751.1 434731 435270 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15115803, 12878731, 13129938; Product type e : enzyme; nucleoprotein/polynucleotide-associated enzyme 434731..435270 Escherichia coli UMN026 7157127 YP_002411161.1 CDS frmB NC_011751.1 435395 436228 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800, 15466022; Product type e : enzyme; S-formylglutathione hydrolase complement(435395..436228) Escherichia coli UMN026 7158332 YP_002411162.1 CDS frmA NC_011751.1 436320 437429 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15466022, 87172301, 1731906; Product type e : enzyme; alcohol dehydrogenase complement(436320..437429) Escherichia coli UMN026 7156440 YP_002411163.1 CDS frmR NC_011751.1 437464 437739 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(437464..437739) Escherichia coli UMN026 7156439 YP_002411164.1 CDS yaiO NC_011751.1 437927 438700 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(437927..438700) Escherichia coli UMN026 7156442 YP_002411165.1 CDS yaiX NC_011751.1 438702 439412 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transferase complement(438702..439412) Escherichia coli UMN026 7158333 YP_002411166.1 CDS yaiP NC_011751.1 439261 440457 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated glycosyltransferase complement(439261..440457) Escherichia coli UMN026 7158338 YP_002411167.1 CDS yaiS NC_011751.1 440467 441138 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(440467..441138) Escherichia coli UMN026 7158334 YP_002411168.1 CDS tauA NC_011751.1 441747 442709 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 441747..442709 Escherichia coli UMN026 7158335 YP_002411169.1 CDS tauB NC_011751.1 442722 443489 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 442722..443489 Escherichia coli UMN026 7158030 YP_002411170.1 CDS tauC NC_011751.1 443486 444313 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401024, 96404792; Product type t : transporter; taurine transporter subunit 443486..444313 Escherichia coli UMN026 7158031 YP_002411171.1 CDS tauD NC_011751.1 444310 445161 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 444310..445161 Escherichia coli UMN026 7158032 YP_002411172.1 CDS hemB NC_011751.1 445201 446175 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(445201..446175) Escherichia coli UMN026 7158033 YP_002411173.1 CDS ECUMN_0410 NC_011751.1 446701 449607 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative flagellin-like structural protein 446701..449607 Escherichia coli UMN026 7156651 YP_002411174.1 CDS yaiV NC_011751.1 449648 450316 D Evidence 4 : Homologs of previously reported genes of unknown function; putative DNA-binding transcriptional regulator 449648..450316 Escherichia coli UMN026 7154672 YP_002411175.1 CDS ampH NC_011751.1 450317 451474 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(450317..451474) Escherichia coli UMN026 7158336 YP_002411176.1 CDS ECUMN_0413 NC_011751.1 451612 451806 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 451612..451806 Escherichia coli UMN026 7155741 YP_002411177.1 CDS sbmA NC_011751.1 451826 453046 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 451826..453046 Escherichia coli UMN026 7154673 YP_002411178.1 CDS yaiW NC_011751.1 453059 454153 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative lipoprotein 453059..454153 Escherichia coli UMN026 7157874 YP_002411179.1 CDS yaiY NC_011751.1 454211 454519 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(454211..454519) Escherichia coli UMN026 7158337 YP_002411180.1 CDS yaiZ NC_011751.1 454647 454991 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 454647..454991 Escherichia coli UMN026 7158339 YP_002411181.1 CDS ddl NC_011751.1 455194 456288 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(455194..456288) Escherichia coli UMN026 7158340 YP_002411182.1 CDS ECUMN_0419 NC_011751.1 456366 456524 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 456366..456524 Escherichia coli UMN026 7156125 YP_002411183.1 CDS yaiB NC_011751.1 456750 457010 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 456750..457010 Escherichia coli UMN026 7154674 YP_002411184.1 CDS phoA NC_011751.1 457110 458525 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; alkaline phosphatase 457110..458525 Escherichia coli UMN026 7158328 YP_002411185.1 CDS psiF NC_011751.1 458644 458964 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3533724, 2160940; Product type f : factor; hypothetical protein 458644..458964 Escherichia coli UMN026 7157455 YP_002411186.1 CDS adrA NC_011751.1 459066 460181 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 459066..460181 Escherichia coli UMN026 7157549 YP_002411187.1 CDS proC NC_011751.1 460198 461007 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(460198..461007) Escherichia coli UMN026 7158329 YP_002411188.1 CDS yaiI NC_011751.1 461127 461585 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 461127..461585 Escherichia coli UMN026 7157532 YP_002411189.1 CDS aroL NC_011751.1 461768 462292 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 461768..462292 Escherichia coli UMN026 7158331 YP_002411190.1 CDS yaiA NC_011751.1 462342 462533 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 462342..462533 Escherichia coli UMN026 7155792 YP_002411191.1 CDS aroM NC_011751.1 462791 463468 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 86085675, 3001025; hypothetical protein 462791..463468 Escherichia coli UMN026 7158327 YP_002411192.1 CDS yaiE NC_011751.1 463540 463824 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 463540..463824 Escherichia coli UMN026 7155793 YP_002411193.1 CDS ykiA NC_011751.1 464032 464313 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 464032..464313 Escherichia coli UMN026 7158330 YP_002411194.1 CDS rdgC NC_011751.1 464471 465382 R Required for efficient pilin antigenic variation; recombination associated protein complement(464471..465382) Escherichia coli UMN026 7159457 YP_002411195.1 CDS mak NC_011751.1 465507 466415 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 465507..466415 Escherichia coli UMN026 7157633 YP_002411196.1 CDS araJ NC_011751.1 466558 467742 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(466558..467742) Escherichia coli UMN026 7157040 YP_002411197.1 CDS sbcC NC_011751.1 467868 471011 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC complement(467868..471011) Escherichia coli UMN026 7155765 YP_002411198.1 CDS sbcD NC_011751.1 471008 472210 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD complement(471008..472210) Escherichia coli UMN026 7157872 YP_002411199.1 CDS phoB NC_011751.1 472400 473089 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 472400..473089 Escherichia coli UMN026 7157873 YP_002411200.1 CDS phoR NC_011751.1 473147 474442 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 473147..474442 Escherichia coli UMN026 7157456 YP_002411201.1 CDS brnQ NC_011751.1 474849 476168 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3078876, 6998958, 3550103, 7984428; Product type t : transporter; branched chain amino acid transporter (LIV-II) 474849..476168 Escherichia coli UMN026 7157461 YP_002411202.1 CDS proY NC_011751.1 476244 477617 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease 476244..477617 Escherichia coli UMN026 7155891 YP_002411203.1 CDS malZ NC_011751.1 477773 479590 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92184757, 1706703, 1918057; Product type e : enzyme; maltodextrin glucosidase 477773..479590 Escherichia coli UMN026 7157539 YP_002411204.1 CDS ECUMN_0441 NC_011751.1 479701 481248 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 479701..481248 Escherichia coli UMN026 7157053 YP_002411205.1 CDS acpH NC_011751.1 481269 481850 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase complement(481269..481850) Escherichia coli UMN026 7154675 YP_002411206.1 CDS queA NC_011751.1 482069 483139 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 482069..483139 Escherichia coli UMN026 7155683 YP_002411207.1 CDS tgt NC_011751.1 483195 484322 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA -ribosyltransferase 483195..484322 Escherichia coli UMN026 7157612 YP_002411208.1 CDS yajC NC_011751.1 484345 484677 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 484345..484677 Escherichia coli UMN026 7158051 YP_002411209.1 CDS secD NC_011751.1 484705 486552 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 484705..486552 Escherichia coli UMN026 7158341 YP_002411210.1 CDS secF NC_011751.1 486563 487534 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 486563..487534 Escherichia coli UMN026 7157887 YP_002411211.1 CDS yajD NC_011751.1 487663 488010 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 487663..488010 Escherichia coli UMN026 7157889 YP_002411212.1 CDS tsx NC_011751.1 488048 488932 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91092502, 91358319, 93352541; Product type m : membrane component; nucleoside channel phage T6/colicin K receptor complement(488048..488932) Escherichia coli UMN026 7158342 YP_002411213.1 CDS yajI NC_011751.1 489231 489770 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein complement(489231..489770) Escherichia coli UMN026 7158135 YP_002411214.1 CDS nrdR NC_011751.1 489921 490370 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator NrdR 489921..490370 Escherichia coli UMN026 7158344 YP_002411215.1 CDS ribD NC_011751.1 490374 491477 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 490374..491477 Escherichia coli UMN026 7157306 YP_002411216.1 CDS ribH NC_011751.1 491566 492036 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 491566..492036 Escherichia coli UMN026 7157685 YP_002411217.1 CDS nusB NC_011751.1 492056 492475 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 492056..492475 Escherichia coli UMN026 7157686 YP_002411218.1 CDS thiL NC_011751.1 492553 493530 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 492553..493530 Escherichia coli UMN026 7157339 YP_002411219.1 CDS pgpA NC_011751.1 493508 494023 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 493508..494023 Escherichia coli UMN026 7158059 YP_002411220.1 CDS ECUMN_0457 NC_011751.1 494200 495771 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(494200..495771) Escherichia coli UMN026 7157430 YP_002411221.1 CDS yajO NC_011751.1 496002 496976 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217, 16077126; Product type e : enzyme; aldoketo-oxidoreductase complement(496002..496976) Escherichia coli UMN026 7154676 YP_002411222.1 CDS dxs NC_011751.1 497031 498893 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(497031..498893) Escherichia coli UMN026 7158346 YP_002411223.1 CDS ispA NC_011751.1 498918 499817 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89291702, 91210228; Product type e : enzyme; geranyltranstransferase complement(498918..499817) Escherichia coli UMN026 7156216 YP_002411224.1 CDS xseB NC_011751.1 499817 500059 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(499817..500059) Escherichia coli UMN026 7156862 YP_002411225.1 CDS thiI NC_011751.1 500265 501713 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 500265..501713 Escherichia coli UMN026 7158250 YP_002411226.1 CDS yajL NC_011751.1 501767 502357 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 97039868, 99173753, 99311269; DJ-1 family protein complement(501767..502357) Escherichia coli UMN026 7158058 YP_002411227.1 CDS panE NC_011751.1 502320 503231 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(502320..503231) Escherichia coli UMN026 7158345 YP_002411228.1 CDS yajQ NC_011751.1 503399 503890 D putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 503399..503890 Escherichia coli UMN026 7157380 YP_002411229.1 CDS yajR NC_011751.1 504018 505382 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator family complement(504018..505382) Escherichia coli UMN026 7158347 YP_002411230.1 CDS cyoE NC_011751.1 505531 506421 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(505531..506421) Escherichia coli UMN026 7158348 YP_002411231.1 CDS cyoD NC_011751.1 506433 506762 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 90366572, 92345252, 9378722, 98021084, 11017202, 2162835; Product type c : carrier; cytochrome o ubiquinol oxidase subunit IV complement(506433..506762) Escherichia coli UMN026 7156077 YP_002411232.1 CDS cyoC NC_011751.1 506762 507376 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit III complement(506762..507376) Escherichia coli UMN026 7156076 YP_002411233.1 CDS cyoB NC_011751.1 507366 509357 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit I complement(507366..509357) Escherichia coli UMN026 7156075 YP_002411234.1 CDS cyoA NC_011751.1 509379 510326 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92112945, 92371427, 9378722, 98021084, 11017202, 1322173, 2162835, 2162837, 2165491, 2168206, 8231804, 8618822; Product type c : carrier; cytochrome o ubiquinol oxidase subunit II complement(509379..510326) Escherichia coli UMN026 7156074 YP_002411235.1 CDS ampG NC_011751.1 510786 512261 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(510786..512261) Escherichia coli UMN026 7156073 YP_002411236.1 CDS yajG NC_011751.1 512305 512883 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein complement(512305..512883) Escherichia coli UMN026 7155740 YP_002411237.1 CDS bolA NC_011751.1 513188 513505 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 513188..513505 Escherichia coli UMN026 7158343 YP_002411238.1 CDS ECUMN_0475 NC_011751.1 513439 513702 D Evidence 6 : Doubtful CDS; hypothetical protein 513439..513702 Escherichia coli UMN026 7155889 YP_002411239.1 CDS tig NC_011751.1 513849 515147 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 513849..515147 Escherichia coli UMN026 7154677 YP_002411240.1 CDS clpP NC_011751.1 515393 516016 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 515393..516016 Escherichia coli UMN026 7158071 YP_002411241.1 CDS clpX NC_011751.1 516142 517416 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 516142..517416 Escherichia coli UMN026 7155980 YP_002411242.1 CDS lon NC_011751.1 517604 519958 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094703, 14665623, 8939438, 91072263, 97137085, 2984174, 3042779, 3289547, 7988699, 8226758, 8294008; Product type e : enzyme; DNA-binding ATP-dependent protease La 517604..519958 Escherichia coli UMN026 7157969 YP_002411243.1 CDS hupB NC_011751.1 520167 520439 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 520167..520439 Escherichia coli UMN026 7156999 YP_002411244.1 CDS ppiD NC_011751.1 520631 522502 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9670013; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase 520631..522502 Escherichia coli UMN026 7156733 YP_002411245.1 CDS ybaV NC_011751.1 522653 523024 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 522653..523024 Escherichia coli UMN026 7157508 YP_002411246.1 CDS ybaW NC_011751.1 523118 523516 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 523118..523516 Escherichia coli UMN026 7158361 YP_002411247.1 CDS queC NC_011751.1 523568 524263 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(523568..524263) Escherichia coli UMN026 7158362 YP_002411248.1 CDS ybaE NC_011751.1 524328 526028 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(524328..526028) Escherichia coli UMN026 7157613 YP_002411249.1 CDS cof NC_011751.1 526128 526946 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; thiamin pyrimidine pyrophosphate hydrolase 526128..526946 Escherichia coli UMN026 7158351 YP_002411250.1 CDS ybaO NC_011751.1 527099 527557 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7904973, 10850996; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 527099..527557 Escherichia coli UMN026 7155997 YP_002411251.1 CDS mdlA NC_011751.1 527587 529359 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004, 10850996; Product type pt : putative transporter; putative multidrug transporter membrane/ATP-binding protein 527587..529359 Escherichia coli UMN026 7158357 YP_002411252.1 CDS mdlB NC_011751.1 529352 531133 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004; Product type pt : putative transporter; putative multidrug transporter membrane/ATP-binding protein 529352..531133 Escherichia coli UMN026 7157070 YP_002411253.1 CDS glnK NC_011751.1 531314 531652 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 531314..531652 Escherichia coli UMN026 7157071 YP_002411254.1 CDS amtB NC_011751.1 531682 532968 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22020597, 9618533, 10931328, 1645722, 7984428; Product type t : transporter; ammonium transporter 531682..532968 Escherichia coli UMN026 7156554 YP_002411255.1 CDS tesB NC_011751.1 533017 533877 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86139906, 91250410, 10876240; Product type e : enzyme; acyl-CoA thioesterase II complement(533017..533877) Escherichia coli UMN026 7155742 YP_002411256.1 CDS ybaY NC_011751.1 534095 534667 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative lipoprotein 534095..534667 Escherichia coli UMN026 7158048 YP_002411257.1 CDS ybaZ NC_011751.1 534698 535087 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methylated DNA-protein cysteine alkyltransferase complement(534698..535087) Escherichia coli UMN026 7158363 YP_002411258.1 CDS ybaA NC_011751.1 535388 535741 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 535388..535741 Escherichia coli UMN026 7156341 YP_002411259.1 CDS ylaB NC_011751.1 535783 537333 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(535783..537333) Escherichia coli UMN026 7158349 YP_002411260.1 CDS ylaC NC_011751.1 537497 537967 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(537497..537967) Escherichia coli UMN026 7159458 YP_002411261.1 CDS maa NC_011751.1 538083 538634 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82180540, 91310703, 9600841; Product type e : enzyme; maltose O-acetyltransferase complement(538083..538634) Escherichia coli UMN026 7159459 YP_002411262.1 CDS hha NC_011751.1 538806 539024 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(538806..539024) Escherichia coli UMN026 7157036 YP_002411263.1 CDS ybaJ NC_011751.1 539050 539424 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1956303, 7984428, 14645275; hypothetical protein complement(539050..539424) Escherichia coli UMN026 7156669 YP_002411264.1 CDS acrB NC_011751.1 539970 543119 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351840, 12654283, 15111118, 15155734, 21450803, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system protein complement(539970..543119) Escherichia coli UMN026 7158352 YP_002411265.1 CDS acrA NC_011751.1 543142 544335 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155734, 21450803, 383699, 390095, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system complement(543142..544335) Escherichia coli UMN026 7155688 YP_002411266.1 CDS acrR NC_011751.1 544477 545124 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 544477..545124 Escherichia coli UMN026 7155687 YP_002411267.1 CDS kefA NC_011751.1 545252 548614 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 545252..548614 Escherichia coli UMN026 7155692 YP_002411268.1 CDS ybaM NC_011751.1 548653 548817 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(548653..548817) Escherichia coli UMN026 7156902 YP_002411269.1 CDS priC NC_011751.1 548831 549358 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(548831..549358) Escherichia coli UMN026 7158355 YP_002411270.1 CDS ybaN NC_011751.1 549428 549805 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 549428..549805 Escherichia coli UMN026 7157524 YP_002411271.1 CDS apt NC_011751.1 549958 550509 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 549958..550509 Escherichia coli UMN026 7158356 YP_002411272.1 CDS dnaX NC_011751.1 550638 552569 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 550638..552569 Escherichia coli UMN026 7155755 YP_002411273.1 CDS ybaB NC_011751.1 552622 552951 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15322138, 1698765, 2674903; hypothetical protein 552622..552951 Escherichia coli UMN026 7156193 YP_002411274.1 CDS recR NC_011751.1 552951 553556 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 552951..553556 Escherichia coli UMN026 7158350 YP_002411275.1 CDS htpG NC_011751.1 553666 555540 D molecular chaperone; heat shock protein 90 553666..555540 Escherichia coli UMN026 7157647 YP_002411276.1 CDS adk NC_011751.1 555721 556365 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 555721..556365 Escherichia coli UMN026 7156726 YP_002411277.1 CDS hemH NC_011751.1 556497 557459 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 556497..557459 Escherichia coli UMN026 7155703 YP_002411278.1 CDS aes NC_011751.1 557456 558415 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401025, 98244813, 2051480, 7721718; Product type e : enzyme; acetyl esterase complement(557456..558415) Escherichia coli UMN026 7156657 YP_002411279.1 CDS gsk NC_011751.1 558567 559871 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90155203, 95238302, 2051480; Product type e : enzyme; inosine/guanosine kinase 558567..559871 Escherichia coli UMN026 7155707 YP_002411280.1 CDS ybaL NC_011751.1 560001 561677 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein complement(560001..561677) Escherichia coli UMN026 7156619 YP_002411281.1 CDS fsr NC_011751.1 561915 563135 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 97074653, 8917080; Product type t : transporter; fosmidomycin efflux system, member of the major facilitator superfamily complement(561915..563135) Escherichia coli UMN026 7158354 YP_002411282.1 CDS ushA NC_011751.1 563353 565005 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 563353..565005 Escherichia coli UMN026 7156454 YP_002411283.1 CDS ybaK NC_011751.1 565042 565521 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(565042..565521) Escherichia coli UMN026 7157835 YP_002411284.1 CDS ECUMN_0521 NC_011751.1 565537 565812 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(565537..565812) Escherichia coli UMN026 7158353 YP_002411285.1 CDS ybaP NC_011751.1 565725 566519 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(565725..566519) Escherichia coli UMN026 7157980 YP_002411286.1 CDS copA NC_011751.1 566691 569195 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351646, 20105527, 11167016, 11500054, 9868784; Product type t : transporter; copper exporting ATPase complement(566691..569195) Escherichia coli UMN026 7158358 YP_002411287.1 CDS ybaS NC_011751.1 569458 570390 D catalyzes the formation of glutamate from glutamine; glutaminase 569458..570390 Escherichia coli UMN026 7155998 YP_002411288.1 CDS ybaT NC_011751.1 570393 571685 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative nitrogen-containing metabolite transporter 570393..571685 Escherichia coli UMN026 7158359 YP_002411289.1 CDS siiCA NC_011751.1 572023 573378 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; outer membrane transport protein, type I secretion 572023..573378 Escherichia coli UMN026 7158360 YP_002411290.1 CDS siiEA NC_011751.1 573487 594264 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type f : factor; adhesin for cattle intestine colonization 573487..594264 Escherichia coli UMN026 7157926 YP_002411291.1 CDS siiBA NC_011751.1 594268 596430 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265, 2185213; Product type t : transporter; type I secretion membrane protein, ATP binding protein, protein export 594268..596430 Escherichia coli UMN026 7157928 YP_002411292.1 CDS siiDA NC_011751.1 596427 597602 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; RtxD/HlyD/CyaD protein of type I secretion system 596427..597602 Escherichia coli UMN026 7157925 YP_002411293.1 CDS cueR NC_011751.1 597599 598006 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 597599..598006 Escherichia coli UMN026 7157927 YP_002411294.1 CDS ECUMN_0531 NC_011751.1 598010 598213 R hypothetical protein complement(598010..598213) Escherichia coli UMN026 7156049 YP_002411295.1 CDS ECUMN_0532 NC_011751.1 598210 598632 R hypothetical protein complement(598210..598632) Escherichia coli UMN026 7154679 YP_002411296.1 CDS ECUMN_0533 NC_011751.1 598686 600488 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative adhesin/invasin-like protein complement(598686..600488) Escherichia coli UMN026 7154680 YP_002411297.1 CDS ECUMN_0534 NC_011751.1 600837 601199 D hypothetical protein 600837..601199 Escherichia coli UMN026 7154681 YP_002411298.1 CDS ybbJ NC_011751.1 601384 601839 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(601384..601839) Escherichia coli UMN026 7154682 YP_002411299.1 CDS ybbK NC_011751.1 601839 602756 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative protease, membrane anchored complement(601839..602756) Escherichia coli UMN026 7158367 YP_002411300.1 CDS ybbL NC_011751.1 602902 603579 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein YbbL 602902..603579 Escherichia coli UMN026 7158368 YP_002411301.1 CDS ybbM NC_011751.1 603566 604345 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative ABC transporter permease 603566..604345 Escherichia coli UMN026 7158369 YP_002411302.1 CDS ybbN NC_011751.1 604408 605262 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative thioredoxin domain-containing protein complement(604408..605262) Escherichia coli UMN026 7158370 YP_002411303.1 CDS ybbO NC_011751.1 605323 606132 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; short chain dehydrogenase complement(605323..606132) Escherichia coli UMN026 7158371 YP_002411304.1 CDS tesA NC_011751.1 606122 606748 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91270121, 91324311, 93163029, 93252782, 94179121, 99353977, 1864840, 8432696, 8098033; Product type e : enzyme; multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 complement(606122..606748) Escherichia coli UMN026 7158372 YP_002411305.1 CDS ybbA NC_011751.1 606716 607402 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein YbbA 606716..607402 Escherichia coli UMN026 7158047 YP_002411306.1 CDS ybbP NC_011751.1 607399 609813 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; putative ABC transporter permease 607399..609813 Escherichia coli UMN026 7158365 YP_002411307.1 CDS ybbB NC_011751.1 610418 611512 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(610418..611512) Escherichia coli UMN026 7158373 YP_002411308.1 CDS ybbS NC_011751.1 611581 612507 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(611581..612507) Escherichia coli UMN026 7158366 YP_002411309.1 CDS allA NC_011751.1 612737 613219 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 612737..613219 Escherichia coli UMN026 7158374 YP_002411310.1 CDS allR NC_011751.1 613297 614112 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 613297..614112 Escherichia coli UMN026 7155726 YP_002411311.1 CDS gcl NC_011751.1 614202 615983 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 614202..615983 Escherichia coli UMN026 7155730 YP_002411312.1 CDS hyi NC_011751.1 615996 616772 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20029625, 8440684; Product type e : enzyme; hydroxypyruvate isomerase 615996..616772 Escherichia coli UMN026 7156518 YP_002411313.1 CDS glxR NC_011751.1 616872 617750 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme; tartronate semialdehyde reductase, NADH-dependent 616872..617750 Escherichia coli UMN026 7156769 YP_002411314.1 CDS ybbW NC_011751.1 617920 619374 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1293888; Product type t : transporter; allantoin permease 617920..619374 Escherichia coli UMN026 7156584 YP_002411315.1 CDS allB NC_011751.1 619434 620795 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 619434..620795 Escherichia coli UMN026 7158375 YP_002411316.1 CDS ybbY NC_011751.1 620852 622153 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative purine permease YbbY 620852..622153 Escherichia coli UMN026 7155727 YP_002411317.1 CDS glxK NC_011751.1 622175 623320 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme; glycerate kinase II 622175..623320 Escherichia coli UMN026 7158376 YP_002411318.1 CDS ylbA NC_011751.1 623450 624235 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(623450..624235) Escherichia coli UMN026 7156583 YP_002411319.1 CDS allC NC_011751.1 624246 625481 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(624246..625481) Escherichia coli UMN026 7159460 YP_002411320.1 CDS allD NC_011751.1 625503 626552 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12460564, 20069628, 69151449; Product type e : enzyme; ureidoglycolate dehydrogenase complement(625503..626552) Escherichia coli UMN026 7155728 YP_002411321.1 CDS fdrA NC_011751.1 626869 628536 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 626869..628536 Escherichia coli UMN026 7155729 YP_002411322.1 CDS ylbE NC_011751.1 628546 629805 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 628546..629805 Escherichia coli UMN026 7156322 YP_002411323.1 CDS ylbF NC_011751.1 629816 630631 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 629816..630631 Escherichia coli UMN026 7159461 YP_002411324.1 CDS ybcF NC_011751.1 630628 631521 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2464576, 2644189, 7920643, 7940673, 7984428; Product type pe : putative enzyme; carbamate kinase 630628..631521 Escherichia coli UMN026 7159462 YP_002411325.1 CDS purK NC_011751.1 631648 632715 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(631648..632715) Escherichia coli UMN026 7158377 YP_002411326.1 CDS purE NC_011751.1 632712 633221 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10074353, 8117684, 89123018, 89123019, 92287929, 10574791; Product type e : enzyme; N5-carboxyaminoimidazole ribonucleotide mutase complement(632712..633221) Escherichia coli UMN026 7157579 YP_002411327.1 CDS lpxH NC_011751.1 633339 634061 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(633339..634061) Escherichia coli UMN026 7157576 YP_002411328.1 CDS ppiB NC_011751.1 634064 634558 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 1864365, 8601841, 9298646, 9600841; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase B complement(634064..634558) Escherichia coli UMN026 7157013 YP_002411329.1 CDS cysS NC_011751.1 634732 636117 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 634732..636117 Escherichia coli UMN026 7157506 YP_002411330.1 CDS ybcI NC_011751.1 636153 636674 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(636153..636674) Escherichia coli UMN026 7156092 YP_002411331.1 CDS ybcJ NC_011751.1 636782 636994 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12837795, 1748668, 7567469; Product type pr : putative regulator; hypothetical protein complement(636782..636994) Escherichia coli UMN026 7158379 YP_002411332.1 CDS folD NC_011751.1 636996 637862 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(636996..637862) Escherichia coli UMN026 7158380 YP_002411333.1 CDS sfmA NC_011751.1 638333 638875 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2890624; Product type ps : putative structure; putative fimbrial-like adhesin protein 638333..638875 Escherichia coli UMN026 7156426 YP_002411334.1 CDS sfmC NC_011751.1 639095 639787 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15372038, 2553674; Product type f : factor; pilin chaperone, periplasmic 639095..639787 Escherichia coli UMN026 7157904 YP_002411335.1 CDS sfmD NC_011751.1 639818 642427 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1970114; Product type pf : putative factor; putative outer membrane export usher protein 639818..642427 Escherichia coli UMN026 7157905 YP_002411336.1 CDS sfmH NC_011751.1 642470 643447 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin protein 642470..643447 Escherichia coli UMN026 7157906 YP_002411337.1 CDS sfmF NC_011751.1 643458 643973 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2890624; Product type ps : putative structure; putative fimbrial protein 643458..643973 Escherichia coli UMN026 7157908 YP_002411338.1 CDS fimZ NC_011751.1 643976 644608 R activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ complement(643976..644608) Escherichia coli UMN026 7157907 YP_002411339.1 CDS intD NC_011751.1 644943 646106 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 90036709, 2183007; Product type pe : putative enzyme; putative integrase; DLP12 prophage complement(644943..646106) Escherichia coli UMN026 7155631 YP_002411340.1 CDS ECUMN_0577 NC_011751.1 645962 646363 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Excisionase from phage origin complement(645962..646363) Escherichia coli UMN026 7156844 YP_002411341.1 CDS ECUMN_0578 NC_011751.1 646305 646583 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(646305..646583) Escherichia coli UMN026 7154683 YP_002411342.1 CDS ECUMN_0579 NC_011751.1 646631 646849 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(646631..646849) Escherichia coli UMN026 7154684 YP_002411343.1 CDS ECUMN_0580 NC_011751.1 646942 647259 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(646942..647259) Escherichia coli UMN026 7154685 YP_002411344.1 CDS ECUMN_0581 NC_011751.1 647240 647431 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(647240..647431) Escherichia coli UMN026 7154686 YP_002411345.1 CDS ECUMN_0582 NC_011751.1 647583 648263 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; exonuclease from phage origin complement(647583..648263) Escherichia coli UMN026 7154687 YP_002411346.1 CDS ECUMN_0583 NC_011751.1 648260 649045 R Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin; recombination protein bet from phage origin complement(648260..649045) Escherichia coli UMN026 7154688 YP_002411347.1 CDS ECUMN_0584 NC_011751.1 649051 649347 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative host-nuclease inhibitor protein Gam of bacteriophage complement(649051..649347) Escherichia coli UMN026 7154689 YP_002411348.1 CDS ECUMN_0585 NC_011751.1 649423 649629 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; prophage Kil protein complement(649423..649629) Escherichia coli UMN026 7154690 YP_002411349.1 CDS ECUMN_0586 NC_011751.1 650112 651044 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(650112..651044) Escherichia coli UMN026 7154691 YP_002411350.1 CDS ECUMN_0587 NC_011751.1 651041 651514 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(651041..651514) Escherichia coli UMN026 7154692 YP_002411351.1 CDS ECUMN_0588 NC_011751.1 651596 652351 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; regulatory protein CI from bacteriophage origin complement(651596..652351) Escherichia coli UMN026 7154693 YP_002411352.1 CDS cro NC_011751.1 652390 652620 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; hypothetical protein 652390..652620 Escherichia coli UMN026 7154694 YP_002411353.1 CDS ECUMN_0590 NC_011751.1 652690 653229 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 612476; Product type h : extrachromosomal origin; regulatory protein CII from bacteriophage origin 652690..653229 Escherichia coli UMN026 7156015 YP_002411354.1 CDS ECUMN_0591 NC_011751.1 653226 654245 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2995831; Product type h : extrachromosomal origin; replication protein O frm phage origin 653226..654245 Escherichia coli UMN026 7154695 YP_002411355.1 CDS ECUMN_0592 NC_011751.1 654242 654943 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative replication protein P of bacteriophage 654242..654943 Escherichia coli UMN026 7154696 YP_002411356.1 CDS ECUMN_0593 NC_011751.1 654940 655242 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; ren protein from phage origin 654940..655242 Escherichia coli UMN026 7154697 YP_002411357.1 CDS ECUMN_0594 NC_011751.1 655173 655382 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 655173..655382 Escherichia coli UMN026 7154698 YP_002411358.1 CDS ECUMN_0595 NC_011751.1 655491 656993 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Chromosome segregation ATPase from phage origin, putative coiled-coil complement(655491..656993) Escherichia coli UMN026 7154699 YP_002411359.1 CDS ECUMN_0596 NC_011751.1 657369 657542 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 657369..657542 Escherichia coli UMN026 7154700 YP_002411360.1 CDS ECUMN_0597 NC_011751.1 657806 658414 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 657806..658414 Escherichia coli UMN026 7154701 YP_002411361.1 CDS ECUMN_0598 NC_011751.1 658650 659159 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 658650..659159 Escherichia coli UMN026 7154702 YP_002411362.1 CDS ybcN NC_011751.1 659354 659809 D DLP12 prophage; hypothetical protein 659354..659809 Escherichia coli UMN026 7154703 YP_002411363.1 CDS ninE NC_011751.1 659809 659979 D DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 659809..659979 Escherichia coli UMN026 7158381 YP_002411364.1 CDS ybcO NC_011751.1 659972 660262 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 659972..660262 Escherichia coli UMN026 7157281 YP_002411365.1 CDS rusA NC_011751.1 660259 660621 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 660259..660621 Escherichia coli UMN026 7158382 YP_002411366.1 CDS ybcQ NC_011751.1 660844 661227 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8648624, 9278503; Product type pf : putative factor; putative antitermination protein Q-like protein; DLP12 prophage 660844..661227 Escherichia coli UMN026 7157819 YP_002411367.1 CDS nmpC NC_011751.1 661417 662499 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative outer membrane porin complement(661417..662499) Escherichia coli UMN026 7158383 YP_002411368.1 CDS essD NC_011751.1 663073 663288 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative phage lysis protein S; DLP12 prophage 663073..663288 Escherichia coli UMN026 7157291 YP_002411369.1 CDS ybcS NC_011751.1 663288 663785 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : putative enzyme; putative lysozyme; DLP12 prophage 663288..663785 Escherichia coli UMN026 7156269 YP_002411370.1 CDS Rz NC_011751.1 663770 664249 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Endopeptidase from phage origin 663770..664249 Escherichia coli UMN026 7158385 YP_002411371.1 CDS ECUMN_0608 NC_011751.1 664531 664695 R Evidence 7 : Gene remnant; Product type h : extrachromosomal origin; Arginyl-tRNA synthetase complement(664531..664695) Escherichia coli UMN026 7157860 YP_002411372.1 CDS ECUMN_0609 NC_011751.1 664741 665166 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(664741..665166) Escherichia coli UMN026 7154704 YP_002411373.1 CDS ynfO NC_011751.1 665209 665442 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(665209..665442) Escherichia coli UMN026 7154705 YP_002411374.1 CDS ECUMN_0611 NC_011751.1 665548 665691 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 665548..665691 Escherichia coli UMN026 7159528 YP_002411375.1 CDS nohB NC_011751.1 665831 666376 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92334985; Product type h : extrachromosomal origin; DNA packaging protein; DLP12 prophage 665831..666376 Escherichia coli UMN026 7154706 YP_002411376.1 CDS ECUMN_0613 NC_011751.1 666351 668276 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; terminase large subunit 666351..668276 Escherichia coli UMN026 7157292 YP_002411377.1 CDS W NC_011751.1 668273 668479 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11302702; Product type h : extrachromosomal origin; Head-to-tail joining protein W (gpW) from bacteriophage origin 668273..668479 Escherichia coli UMN026 7154707 YP_002411378.1 CDS B NC_011751.1 668476 670077 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; portal protein B (Minor capsid protein B) from bacteriophage origin 668476..670077 Escherichia coli UMN026 7158213 YP_002411379.1 CDS C NC_011751.1 669944 671389 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; Minor capsid protein C from bacteriophage origin 669944..671389 Escherichia coli UMN026 7155846 YP_002411380.1 CDS D NC_011751.1 671399 671731 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6233140; Product type h : extrachromosomal origin; head decoration protein (Major capsid protein D) from bacteriophage origin 671399..671731 Escherichia coli UMN026 7155900 YP_002411381.1 CDS ECUMN_0618 NC_011751.1 671787 672812 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; major head protein (Major coat protein) from bacteriophage origin 671787..672812 Escherichia coli UMN026 7156097 YP_002411382.1 CDS fI NC_011751.1 672854 673249 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6279661; Product type h : extrachromosomal origin; DNA packaging protein FI from bacteriophage origin 672854..673249 Escherichia coli UMN026 7154708 YP_002411383.1 CDS fII NC_011751.1 673261 673614 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; Tail attachment protein (Minor capsid protein FII) from bacteriophage origin 673261..673614 Escherichia coli UMN026 7156350 YP_002411384.1 CDS ECUMN_0621 NC_011751.1 673626 674204 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GpZ) 673626..674204 Escherichia coli UMN026 7156354 YP_002411385.1 CDS ECUMN_0622 NC_011751.1 674201 674596 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 674201..674596 Escherichia coli UMN026 7154709 YP_002411386.1 CDS ECUMN_0623 NC_011751.1 674574 675344 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 674574..675344 Escherichia coli UMN026 7154710 YP_002411387.1 CDS ECUMN_0624 NC_011751.1 675360 675782 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein G 675360..675782 Escherichia coli UMN026 7154711 YP_002411388.1 CDS ECUMN_0625 NC_011751.1 675764 676198 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein T 675764..676198 Escherichia coli UMN026 7154712 YP_002411389.1 CDS ECUMN_0626 NC_011751.1 676191 678746 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein H 676191..678746 Escherichia coli UMN026 7154713 YP_002411390.1 CDS ECUMN_0627 NC_011751.1 678743 679072 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 678743..679072 Escherichia coli UMN026 7154714 YP_002411391.1 CDS ECUMN_0628 NC_011751.1 679072 679770 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 679072..679770 Escherichia coli UMN026 7154715 YP_002411392.1 CDS ECUMN_0629 NC_011751.1 679776 680519 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber component K of prophage 679776..680519 Escherichia coli UMN026 7154716 YP_002411393.1 CDS ECUMN_0630 NC_011751.1 680417 681088 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I 680417..681088 Escherichia coli UMN026 7154717 YP_002411394.1 CDS ECUMN_0631 NC_011751.1 681148 684645 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J of prophage 681148..684645 Escherichia coli UMN026 7154718 YP_002411395.1 CDS ECUMN_0632 NC_011751.1 684706 687075 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; putative side tail fiber protein from prophage 684706..687075 Escherichia coli UMN026 7154719 YP_002411396.1 CDS ECUMN_0633 NC_011751.1 687072 687353 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 687072..687353 Escherichia coli UMN026 7154720 YP_002411397.1 CDS ECUMN_0634 NC_011751.1 687363 688067 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 687363..688067 Escherichia coli UMN026 7154721 YP_002411398.1 CDS ECUMN_0635 NC_011751.1 688078 688371 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 688078..688371 Escherichia coli UMN026 7154722 YP_002411399.1 CDS appY NC_011751.1 689047 689796 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89155479, 94350824, 3295784, 2823063; Product type r : regulator; DNA-binding transcriptional activator; DLP12 prophage 689047..689796 Escherichia coli UMN026 7154723 YP_002411400.1 CDS ompT NC_011751.1 690046 690999 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(690046..690999) Escherichia coli UMN026 7155754 YP_002411401.1 CDS ECUMN_0638 NC_011751.1 691403 691519 R Evidence 6 : Doubtful CDS; hypothetical protein complement(691403..691519) Escherichia coli UMN026 7157350 YP_002411402.1 CDS envY NC_011751.1 691513 692274 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6317653, 2536924; Product type r : regulator; DNA-binding transcriptional activator of porin biosynthesis complement(691513..692274) Escherichia coli UMN026 7154724 YP_002411403.1 CDS ybcH NC_011751.1 692457 693347 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(692457..693347) Escherichia coli UMN026 7156256 YP_002411404.1 CDS nfrA NC_011751.1 693348 696320 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component; bacteriophage N4 receptor, outer membrane subunit complement(693348..696320) Escherichia coli UMN026 7158378 YP_002411405.1 CDS nfrB NC_011751.1 696307 698544 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component; bacteriophage N4 adsorption protein B complement(696307..698544) Escherichia coli UMN026 7157268 YP_002411406.1 CDS ECUMN_0643 NC_011751.1 699092 699262 D Evidence 6 : Doubtful CDS; hypothetical protein 699092..699262 Escherichia coli UMN026 7157269 YP_002411407.1 CDS ECUMN_0644 NC_011751.1 699482 699910 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(699482..699910) Escherichia coli UMN026 7154725 YP_002411408.1 CDS ECUMN_0645 NC_011751.1 699938 700384 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(699938..700384) Escherichia coli UMN026 7154726 YP_002411409.1 CDS ECUMN_0646 NC_011751.1 700715 700957 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(700715..700957) Escherichia coli UMN026 7154727 YP_002411410.1 CDS ECUMN_0647 NC_011751.1 700991 701227 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(700991..701227) Escherichia coli UMN026 7154728 YP_002411411.1 CDS yhhI NC_011751.1 701205 702341 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ph : phenotype; putative transposase complement(701205..702341) Escherichia coli UMN026 7154729 YP_002411412.1 CDS ECUMN_0649 NC_011751.1 702420 702689 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(702420..702689) Escherichia coli UMN026 7159176 YP_002411413.1 CDS ECUMN_0650 NC_011751.1 702707 703168 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(702707..703168) Escherichia coli UMN026 7154730 YP_002411414.1 CDS ECUMN_0651 NC_011751.1 703171 703371 R Evidence 6 : Doubtful CDS; hypothetical protein complement(703171..703371) Escherichia coli UMN026 7154731 YP_002411415.1 CDS ECUMN_0654 NC_011751.1 704732 705043 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(704732..705043) Escherichia coli UMN026 7159178 YP_002411416.1 CDS ECUMN_0655 NC_011751.1 705136 706146 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(705136..706146) Escherichia coli UMN026 7154733 YP_002411417.1 CDS ECUMN_0656 NC_011751.1 706178 706492 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(706178..706492) Escherichia coli UMN026 7154734 YP_002411418.1 CDS ECUMN_0657 NC_011751.1 706546 707586 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(706546..707586) Escherichia coli UMN026 7154735 YP_002411419.1 CDS ECUMN_0658 NC_011751.1 707698 708738 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(707698..708738) Escherichia coli UMN026 7154736 YP_002411420.1 CDS ECUMN_0659 NC_011751.1 708764 709063 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(708764..709063) Escherichia coli UMN026 7154737 YP_002411421.1 CDS cusS NC_011751.1 709432 710892 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 11283292, 11399769; Product type r : regulator; sensor kinase CusS complement(709432..710892) Escherichia coli UMN026 7154738 YP_002411422.1 CDS cusR NC_011751.1 710870 711553 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(710870..711553) Escherichia coli UMN026 7156055 YP_002411423.1 CDS cusC NC_011751.1 711704 713092 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 711704..713092 Escherichia coli UMN026 7156054 YP_002411424.1 CDS cusF NC_011751.1 713116 713448 D Evidence 2b : Function of strongly homologous gene; PubMedId : 21125583, 11283292, 11399769, 12813074; Product type f : factor; periplasmic copper-binding protein 713116..713448 Escherichia coli UMN026 7156052 YP_002411425.1 CDS cusB NC_011751.1 713464 714687 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 713464..714687 Escherichia coli UMN026 7156053 YP_002411426.1 CDS cusA NC_011751.1 714699 717842 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 21125583, 21178899, 21450803, 11399769, 12813074, 1711024, 7984428; Product type t : transporter; copper/silver efflux system, membrane component 714699..717842 Escherichia coli UMN026 7156051 YP_002411427.1 CDS pheP NC_011751.1 717944 719320 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91267923, 94042931, 8626334; Product type t : transporter; phenylalanine transporter 717944..719320 Escherichia coli UMN026 7156050 YP_002411428.1 CDS ybdG NC_011751.1 719388 720635 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein complement(719388..720635) Escherichia coli UMN026 7157436 YP_002411429.1 CDS nfnB NC_011751.1 720743 721396 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(720743..721396) Escherichia coli UMN026 7158394 YP_002411430.1 CDS ybdF NC_011751.1 721475 721978 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(721475..721978) Escherichia coli UMN026 7157266 YP_002411431.1 CDS ybdJ NC_011751.1 721923 722171 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(721923..722171) Escherichia coli UMN026 7158393 YP_002411432.1 CDS ybdK NC_011751.1 722237 723355 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(722237..723355) Escherichia coli UMN026 7158396 YP_002411433.1 CDS ECUMN_0672 NC_011751.1 723367 723543 D Evidence 6 : Doubtful CDS; hypothetical protein 723367..723543 Escherichia coli UMN026 7158397 YP_002411434.1 CDS hokE NC_011751.1 723773 723961 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99291074; Product type f : factor; toxic polypeptide, small 723773..723961 Escherichia coli UMN026 7154739 YP_002411435.1 CDS hokE NC_011751.1 724311 724463 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99291074; Product type f : factor; toxic polypeptide, small 724311..724463 Escherichia coli UMN026 7156694 YP_002411436.1 CDS entD NC_011751.1 724585 725355 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89313305, 90132534, 91035252, 8939709, 9214294; Product type e : enzyme; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(724585..725355) Escherichia coli UMN026 7156695 YP_002411437.1 CDS fepA NC_011751.1 725380 727620 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(725380..727620) Escherichia coli UMN026 7156251 YP_002411438.1 CDS fes NC_011751.1 727941 729065 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92291125, 94198561, 2974033; Product type e : enzyme; enterobactin/ferric enterobactin esterase 727941..729065 Escherichia coli UMN026 7156333 YP_002411439.1 CDS ybdZ NC_011751.1 729068 729286 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 729068..729286 Escherichia coli UMN026 7156339 YP_002411440.1 CDS entF NC_011751.1 729283 733164 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 729283..733164 Escherichia coli UMN026 7158400 YP_002411441.1 CDS fepE NC_011751.1 733260 734498 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 733260..734498 Escherichia coli UMN026 7156253 YP_002411442.1 CDS fepC NC_011751.1 734510 735325 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(734510..735325) Escherichia coli UMN026 7156337 YP_002411443.1 CDS fepG NC_011751.1 735322 736314 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(735322..736314) Escherichia coli UMN026 7156335 YP_002411444.1 CDS fepD NC_011751.1 736311 737315 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(736311..737315) Escherichia coli UMN026 7156338 YP_002411445.1 CDS ybdA NC_011751.1 737426 738676 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 737426..738676 Escherichia coli UMN026 7156336 YP_002411446.1 CDS fepB NC_011751.1 738680 739636 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(738680..739636) Escherichia coli UMN026 7158390 YP_002411447.1 CDS entC NC_011751.1 739825 741000 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123153, 90165423, 90241936, 2110093, 2139473; Product type e : enzyme; isochorismate synthase 1 739825..741000 Escherichia coli UMN026 7156334 YP_002411448.1 CDS entE NC_011751.1 741010 742620 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 741010..742620 Escherichia coli UMN026 7156250 YP_002411449.1 CDS entB NC_011751.1 742634 743491 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20183918, 90241937, 91035252, 9485415, 97361959, 2521621, 2521622; Product type e : enzyme; isochorismatase 742634..743491 Escherichia coli UMN026 7156252 YP_002411450.1 CDS entA NC_011751.1 743491 744237 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 743491..744237 Escherichia coli UMN026 7156249 YP_002411451.1 CDS ybdB NC_011751.1 744240 744653 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2521621, 2521622, 15808744; Product type pe : putative enzyme; hypothetical protein 744240..744653 Escherichia coli UMN026 7156248 YP_002411452.1 CDS cstA NC_011751.1 744834 746939 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91162636, 2521622; Product type pf : putative factor; carbon starvation protein 744834..746939 Escherichia coli UMN026 7158391 YP_002411453.1 CDS ybdD NC_011751.1 747093 747290 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 747093..747290 Escherichia coli UMN026 7156047 YP_002411454.1 CDS ybdH NC_011751.1 747300 748388 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(747300..748388) Escherichia coli UMN026 7158392 YP_002411455.1 CDS ybdL NC_011751.1 748496 749656 D catalyzes the transfer of an amino moiety; putative aminotransferase 748496..749656 Escherichia coli UMN026 7158395 YP_002411456.1 CDS ibrB NC_011751.1 749657 750286 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator complement(749657..750286) Escherichia coli UMN026 7158398 YP_002411457.1 CDS ibrA NC_011751.1 750259 751479 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator complement(750259..751479) Escherichia coli UMN026 7156783 YP_002411458.1 CDS ybdO NC_011751.1 751626 752564 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(751626..752564) Escherichia coli UMN026 7156782 YP_002411459.1 CDS dsbG NC_011751.1 752736 753482 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(752736..753482) Escherichia coli UMN026 7158399 YP_002411460.1 CDS ahpC NC_011751.1 753854 754417 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 753854..754417 Escherichia coli UMN026 7156205 YP_002411461.1 CDS ahpF NC_011751.1 754588 756153 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89197774, 1592833; Product type e : enzyme; alkyl hydroperoxide reductase, F52a subunit 754588..756153 Escherichia coli UMN026 7155717 YP_002411462.1 CDS uspG NC_011751.1 756274 756702 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12071968; Product type f : factor; universal stress protein UP12 complement(756274..756702) Escherichia coli UMN026 7155718 YP_002411463.1 CDS rnk NC_011751.1 757058 757468 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(757058..757468) Escherichia coli UMN026 7158196 YP_002411464.1 CDS rna NC_011751.1 757698 758504 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90151658, 90264307, 2253883, 8188249; Product type e : enzyme; ribonuclease I complement(757698..758504) Escherichia coli UMN026 7157715 YP_002411465.1 CDS citT NC_011751.1 758618 760081 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9696764; Product type t : transporter; citrate:succinate antiporter complement(758618..760081) Escherichia coli UMN026 7157705 YP_002411466.1 CDS citG NC_011751.1 760131 761009 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(760131..761009) Escherichia coli UMN026 7155973 YP_002411467.1 CDS citX NC_011751.1 760984 761535 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase complement(760984..761535) Escherichia coli UMN026 7155972 YP_002411468.1 CDS citF NC_011751.1 761539 763071 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme; citrate lyase, citrate-ACP transferase subunit alpha complement(761539..763071) Escherichia coli UMN026 7155974 YP_002411469.1 CDS citE NC_011751.1 763082 763990 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme; citrate lyase, citryl-ACP lyase subunit beta complement(763082..763990) Escherichia coli UMN026 7155971 YP_002411470.1 CDS citD NC_011751.1 763987 764283 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(763987..764283) Escherichia coli UMN026 7155970 YP_002411471.1 CDS citC NC_011751.1 764298 765356 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme; citrate lyase synthetase complement(764298..765356) Escherichia coli UMN026 7155969 YP_002411472.1 CDS citA NC_011751.1 765736 767394 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11889485, 21885746, 9701802; Product type r : regulator; sensory histidine kinase in two-component regulatory system with citB 765736..767394 Escherichia coli UMN026 7155968 YP_002411473.1 CDS dpiA NC_011751.1 767363 768043 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 767363..768043 Escherichia coli UMN026 7155966 YP_002411474.1 CDS dcuC NC_011751.1 768084 769469 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(768084..769469) Escherichia coli UMN026 7155967 YP_002411475.1 CDS pagP NC_011751.1 770058 770618 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 770058..770618 Escherichia coli UMN026 7156120 YP_002411476.1 CDS cspE NC_011751.1 770793 771002 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 770793..771002 Escherichia coli UMN026 7156008 YP_002411477.1 CDS crcB NC_011751.1 771056 771439 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(771056..771439) Escherichia coli UMN026 7156038 YP_002411478.1 CDS ybeM NC_011751.1 771757 772320 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidase 771757..772320 Escherichia coli UMN026 7156009 YP_002411479.1 CDS tatE NC_011751.1 772449 772652 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 772449..772652 Escherichia coli UMN026 7158406 YP_002411480.1 CDS lipA NC_011751.1 772753 773718 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(772753..773718) Escherichia coli UMN026 7158029 YP_002411481.1 CDS ybeF NC_011751.1 773927 774880 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12218038; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(773927..774880) Escherichia coli UMN026 7156982 YP_002411482.1 CDS ECUMN_0722 NC_011751.1 774939 775088 D Evidence 6 : Doubtful CDS; hypothetical protein 774939..775088 Escherichia coli UMN026 7158404 YP_002411483.1 CDS lipB NC_011751.1 775140 775781 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(775140..775781) Escherichia coli UMN026 7154740 YP_002411484.1 CDS ybeD NC_011751.1 775882 776145 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8444795; hypothetical protein complement(775882..776145) Escherichia coli UMN026 7156983 YP_002411485.1 CDS dacA NC_011751.1 776255 777466 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A complement(776255..777466) Escherichia coli UMN026 7158403 YP_002411486.1 CDS rlpA NC_011751.1 777606 778694 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88058785, 2644207; Product type lp : lipoprotein; rare lipoprotein A complement(777606..778694) Escherichia coli UMN026 7156099 YP_002411487.1 CDS mrdB NC_011751.1 778705 779817 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123070, 90036736, 91072213, 3316191; Product type cp : cell process; cell wall shape-determining protein complement(778705..779817) Escherichia coli UMN026 7157697 YP_002411488.1 CDS mrdA NC_011751.1 779820 781721 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86196149, 87030266, 89174517, 2644207; Product type e : enzyme; penicillin-binding protein 2 complement(779820..781721) Escherichia coli UMN026 7157178 YP_002411489.1 CDS ybeA NC_011751.1 781752 782219 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(781752..782219) Escherichia coli UMN026 7157177 YP_002411490.1 CDS ybeB NC_011751.1 782223 782540 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(782223..782540) Escherichia coli UMN026 7158401 YP_002411491.1 CDS phpB NC_011751.1 782800 783411 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7929373; Product type pe : putative enzyme; putative phosphatase with phosphoglycerate mutase domain complement(782800..783411) Escherichia coli UMN026 7158402 YP_002411492.1 CDS nadD NC_011751.1 783435 784076 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(783435..784076) Escherichia coli UMN026 7157464 YP_002411493.1 CDS holA NC_011751.1 784078 785109 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(784078..785109) Escherichia coli UMN026 7157224 YP_002411494.1 CDS rlpB NC_011751.1 785109 785690 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(785109..785690) Escherichia coli UMN026 7156696 YP_002411495.1 CDS leuS NC_011751.1 785705 788287 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(785705..788287) Escherichia coli UMN026 7157698 YP_002411496.1 CDS ybeL NC_011751.1 788522 789004 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11373298, 12105207, 3320963, 7567469; hypothetical protein 788522..789004 Escherichia coli UMN026 7156948 YP_002411497.1 CDS ybeQ NC_011751.1 789075 790052 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(789075..790052) Escherichia coli UMN026 7158405 YP_002411498.1 CDS ybeR NC_011751.1 790216 790923 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 790216..790923 Escherichia coli UMN026 7158407 YP_002411499.1 CDS djlB NC_011751.1 790920 792347 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12183460, 10574456; Product type pf : putative factor; putative DnaJ-class chaperone 790920..792347 Escherichia coli UMN026 7158408 YP_002411500.1 CDS ybeT NC_011751.1 792357 792911 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(792357..792911) Escherichia coli UMN026 7156173 YP_002411501.1 CDS ybeU NC_011751.1 793013 793720 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 793013..793720 Escherichia coli UMN026 7158409 YP_002411502.1 CDS djlC NC_011751.1 793717 795168 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 12054669; Product type f : factor; Hsc56 co-chaperone of HscC 793717..795168 Escherichia coli UMN026 7158410 YP_002411503.1 CDS hscC NC_011751.1 795228 796898 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 14734171, 22055095, 9735342; Product type f : factor; Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription complement(795228..796898) Escherichia coli UMN026 7156174 YP_002411504.1 CDS rihA NC_011751.1 796982 797917 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(796982..797917) Escherichia coli UMN026 7156716 YP_002411505.1 CDS gltL NC_011751.1 798035 798760 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter ATP-binding protein complement(798035..798760) Escherichia coli UMN026 7157688 YP_002411506.1 CDS gltK NC_011751.1 798760 799434 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein complement(798760..799434) Escherichia coli UMN026 7156579 YP_002411507.1 CDS gltJ NC_011751.1 799434 800174 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein complement(799434..800174) Escherichia coli UMN026 7156578 YP_002411508.1 CDS gltI NC_011751.1 800344 801252 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1091636, 1091635, 10493123, 8740179, 10972807; Product type t : transporter; glutamate and aspartate transporter subunit complement(800344..801252) Escherichia coli UMN026 7156577 YP_002411509.1 CDS lnt NC_011751.1 801649 803187 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(801649..803187) Escherichia coli UMN026 7156576 YP_002411510.1 CDS ybeX NC_011751.1 803212 804090 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779764; Product type pt : putative transporter; hypothetical protein complement(803212..804090) Escherichia coli UMN026 7156993 YP_002411511.1 CDS ybeY NC_011751.1 804180 804647 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511207; Product type pe : putative enzyme; putative metalloprotease complement(804180..804647) Escherichia coli UMN026 7158411 YP_002411512.1 CDS ybeZ NC_011751.1 804644 805723 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12762842; Product type pe : putative enzyme; hypothetical protein complement(804644..805723) Escherichia coli UMN026 7158412 YP_002411513.1 CDS miaB NC_011751.1 805837 807261 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(805837..807261) Escherichia coli UMN026 7158413 YP_002411514.1 CDS ubiF NC_011751.1 807407 808582 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 807407..808582 Escherichia coli UMN026 7157129 YP_002411515.1 CDS ECUMN_0757 NC_011751.1 809269 809421 D Evidence 6 : Doubtful CDS; hypothetical protein 809269..809421 Escherichia coli UMN026 7155647 YP_002411516.1 CDS ECUMN_0758 NC_011751.1 809774 810037 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 809774..810037 Escherichia coli UMN026 7155645 YP_002411517.1 CDS asnB NC_011751.1 810252 811916 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(810252..811916) Escherichia coli UMN026 7154742 YP_002411518.1 CDS nagD NC_011751.1 812313 813065 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16430214, 89343637; Product type e : enzyme; UMP phosphatase complement(812313..813065) Escherichia coli UMN026 7155814 YP_002411519.1 CDS nagC NC_011751.1 813113 814333 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15066032, 90136533, 91171292, 92114782, 92356048, 2190615, 2668691, 7545108; Product type r : regulator; DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine complement(813113..814333) Escherichia coli UMN026 7157230 YP_002411520.1 CDS nagA NC_011751.1 814342 815490 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(814342..815490) Escherichia coli UMN026 7157229 YP_002411521.1 CDS nagB NC_011751.1 815550 816350 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(815550..816350) Escherichia coli UMN026 7157227 YP_002411522.1 CDS nagE NC_011751.1 816683 818629 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 816683..818629 Escherichia coli UMN026 7157228 YP_002411523.1 CDS glnS NC_011751.1 818832 820496 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 818832..820496 Escherichia coli UMN026 7157231 YP_002411524.1 CDS ybfM NC_011751.1 820944 822350 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2118530, 9636669; Product type pt : putative transporter; putative outer membrane porin 820944..822350 Escherichia coli UMN026 7156558 YP_002411525.1 CDS ybfN NC_011751.1 822400 822726 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 822400..822726 Escherichia coli UMN026 7158417 YP_002411526.1 CDS fur NC_011751.1 822811 823257 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(822811..823257) Escherichia coli UMN026 7158418 YP_002411527.1 CDS ECUMN_0769 NC_011751.1 823302 823556 D Evidence 6 : Doubtful CDS; hypothetical protein 823302..823556 Escherichia coli UMN026 7156479 YP_002411528.1 CDS fldA NC_011751.1 823546 824076 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(823546..824076) Escherichia coli UMN026 7154743 YP_002411529.1 CDS ybfE NC_011751.1 824216 824509 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20223640, 12427949; Product type cp : cell process; LexA regulated protein complement(824216..824509) Escherichia coli UMN026 7156375 YP_002411530.1 CDS ybfF NC_011751.1 824649 825413 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme; hypothetical protein complement(824649..825413) Escherichia coli UMN026 7158415 YP_002411531.1 CDS seqA NC_011751.1 825598 826143 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 825598..826143 Escherichia coli UMN026 7158416 YP_002411532.1 CDS pgm NC_011751.1 826169 827809 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 826169..827809 Escherichia coli UMN026 7157896 YP_002411533.1 CDS ybfP NC_011751.1 828014 828508 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 828014..828508 Escherichia coli UMN026 7157429 YP_002411534.1 CDS kdpE NC_011751.1 828620 829297 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(828620..829297) Escherichia coli UMN026 7158419 YP_002411535.1 CDS kdpD NC_011751.1 829294 831978 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(829294..831978) Escherichia coli UMN026 7156894 YP_002411536.1 CDS kdpC NC_011751.1 831971 832543 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(831971..832543) Escherichia coli UMN026 7156893 YP_002411537.1 CDS kdpB NC_011751.1 832552 834600 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(832552..834600) Escherichia coli UMN026 7156892 YP_002411538.1 CDS kdpA NC_011751.1 834623 836296 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(834623..836296) Escherichia coli UMN026 7156891 YP_002411539.1 CDS ybfA NC_011751.1 836698 836904 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 836698..836904 Escherichia coli UMN026 7156890 YP_002411540.1 CDS ECUMN_0782 NC_011751.1 837429 837782 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 837429..837782 Escherichia coli UMN026 7158414 YP_002411541.1 CDS ECUMN_0783 NC_011751.1 837865 838149 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 837865..838149 Escherichia coli UMN026 7154744 YP_002411542.1 CDS ECUMN_0784 NC_011751.1 838162 838569 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 838162..838569 Escherichia coli UMN026 7154745 YP_002411543.1 CDS ybgA NC_011751.1 838654 839163 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6325460, 8387990; hypothetical protein 838654..839163 Escherichia coli UMN026 7154746 YP_002411544.1 CDS phr NC_011751.1 839160 840578 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 839160..840578 Escherichia coli UMN026 7158420 YP_002411545.1 CDS ybgH NC_011751.1 840620 842101 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15175316; Product type pt : putative transporter; putative transporter complement(840620..842101) Escherichia coli UMN026 7157465 YP_002411546.1 CDS ybgI NC_011751.1 842372 843115 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14519207; putative hydrolase-oxidase 842372..843115 Escherichia coli UMN026 7158424 YP_002411547.1 CDS ybgJ NC_011751.1 843138 843794 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase subunit 843138..843794 Escherichia coli UMN026 7158425 YP_002411548.1 CDS ybgK NC_011751.1 843788 844720 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase subunit 843788..844720 Escherichia coli UMN026 7158426 YP_002411549.1 CDS ybgL NC_011751.1 844710 845444 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729609; Product type pe : putative enzyme; LamB/YcsF family protein 844710..845444 Escherichia coli UMN026 7158427 YP_002411550.1 CDS nei NC_011751.1 845480 846271 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 845480..846271 Escherichia coli UMN026 7158428 YP_002411551.1 CDS abrB NC_011751.1 846268 847314 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8002588; Product type ph : phenotype; hypothetical protein complement(846268..847314) Escherichia coli UMN026 7157263 YP_002411552.1 CDS ybgO NC_011751.1 847466 848527 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(847466..848527) Escherichia coli UMN026 7155670 YP_002411553.1 CDS ybgP NC_011751.1 848524 849255 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10049807; Product type pf : putative factor; putative exported chaperone, PapD family complement(848524..849255) Escherichia coli UMN026 7158429 YP_002411554.1 CDS ybgQ NC_011751.1 849271 851772 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(849271..851772) Escherichia coli UMN026 7158430 YP_002411555.1 CDS ECUMN_0797 NC_011751.1 851781 852434 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative fimbrial-like adhesin protein complement(851781..852434) Escherichia coli UMN026 7158431 YP_002411556.1 CDS gltA NC_011751.1 852737 854020 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(852737..854020) Escherichia coli UMN026 7154747 YP_002411557.1 CDS sdhC NC_011751.1 854729 855118 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6237244, 89076355, 89123360, 9521736, 99414342, 11259408, 3309132, 6383359, 9822661; Product type m : membrane component; succinate dehydrogenase cytochrome b556 large membrane subunit 854729..855118 Escherichia coli UMN026 7156573 YP_002411558.1 CDS sdhD NC_011751.1 855112 855459 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82124790, 89076355, 9521736, 99414342, 6383359; Product type m : membrane component; succinate dehydrogenase cytochrome b556 small membrane subunit 855112..855459 Escherichia coli UMN026 7157882 YP_002411559.1 CDS sdhA NC_011751.1 855459 857225 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 855459..857225 Escherichia coli UMN026 7157883 YP_002411560.1 CDS sdhB NC_011751.1 857241 857957 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 857241..857957 Escherichia coli UMN026 7157880 YP_002411561.1 CDS sucA NC_011751.1 858307 861108 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 858307..861108 Escherichia coli UMN026 7157881 YP_002411562.1 CDS sucB NC_011751.1 861123 862340 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 861123..862340 Escherichia coli UMN026 7157998 YP_002411563.1 CDS sucC NC_011751.1 862615 863781 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 862615..863781 Escherichia coli UMN026 7157999 YP_002411564.1 CDS sucD NC_011751.1 863781 864650 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 863781..864650 Escherichia coli UMN026 7158000 YP_002411565.1 CDS ECUMN_0807 NC_011751.1 864695 865045 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 864695..865045 Escherichia coli UMN026 7157836 YP_002411566.1 CDS ECUMN_0808 NC_011751.1 865316 866221 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-like transcriptional regulator 865316..866221 Escherichia coli UMN026 7154748 YP_002411567.1 CDS ECUMN_0809 NC_011751.1 866255 866857 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(866255..866857) Escherichia coli UMN026 7154749 YP_002411568.1 CDS ECUMN_0810 NC_011751.1 866867 868519 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Fumarate hydratase class I subunit beta complement(866867..868519) Escherichia coli UMN026 7154750 YP_002411569.1 CDS ECUMN_0811 NC_011751.1 868627 869928 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative symport protein complement(868627..869928) Escherichia coli UMN026 7154751 YP_002411570.1 CDS ECUMN_0812 NC_011751.1 870068 870385 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(870068..870385) Escherichia coli UMN026 7154752 YP_002411571.1 CDS ECUMN_0813 NC_011751.1 870382 871752 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11748244; Product type pe : putative enzyme; putative 3-methylaspartate ammonia-lyase, glutamate mutase complement(870382..871752) Escherichia coli UMN026 7154753 YP_002411572.1 CDS ECUMN_0814 NC_011751.1 871756 872997 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate ammonia-lyase complement(871756..872997) Escherichia coli UMN026 7154754 YP_002411573.1 CDS ECUMN_0815 NC_011751.1 872997 874442 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate mutase E chain complement(872997..874442) Escherichia coli UMN026 7154755 YP_002411574.1 CDS glmL NC_011751.1 874461 875849 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7880251; Product type e : enzyme; glutamate mutase, large subunit complement(874461..875849) Escherichia coli UMN026 7154756 YP_002411575.1 CDS ECUMN_0817 NC_011751.1 875849 876361 R converts methylaspartate to L-glutamate; methylaspartate mutase subunit S complement(875849..876361) Escherichia coli UMN026 7156544 YP_002411576.1 CDS ECUMN_0818 NC_011751.1 876485 876652 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(876485..876652) Escherichia coli UMN026 7154757 YP_002411577.1 CDS ECUMN_0819 NC_011751.1 876846 877268 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(876846..877268) Escherichia coli UMN026 7154758 YP_002411578.1 CDS ECUMN_0820 NC_011751.1 877349 878293 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(877349..878293) Escherichia coli UMN026 7154759 YP_002411579.1 CDS cydA NC_011751.1 879099 880667 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 1689724, 1724280, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase, subunit I 879099..880667 Escherichia coli UMN026 7154760 YP_002411580.1 CDS cydB NC_011751.1 880683 881822 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase, subunit II 880683..881822 Escherichia coli UMN026 7156065 YP_002411581.1 CDS ybgE NC_011751.1 881950 882243 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 881950..882243 Escherichia coli UMN026 7156066 YP_002411582.1 CDS ybgC NC_011751.1 882393 882797 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 882393..882797 Escherichia coli UMN026 7158422 YP_002411583.1 CDS tolQ NC_011751.1 882794 883486 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 882794..883486 Escherichia coli UMN026 7158421 YP_002411584.1 CDS tolR NC_011751.1 883490 883918 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 883490..883918 Escherichia coli UMN026 7158084 YP_002411585.1 CDS tolA NC_011751.1 883983 885248 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 883983..885248 Escherichia coli UMN026 7158085 YP_002411586.1 CDS tolB NC_011751.1 885381 886673 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 885381..886673 Escherichia coli UMN026 7158081 YP_002411587.1 CDS pal NC_011751.1 886708 887229 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790745, 87133578, 92244043, 99403391, 11173492, 2687247; Product type lp : lipoprotein; peptidoglycan-associated outer membrane lipoprotein 886708..887229 Escherichia coli UMN026 7158082 YP_002411588.1 CDS ybgF NC_011751.1 887239 888030 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 887239..888030 Escherichia coli UMN026 7157376 YP_002411589.1 CDS nadA NC_011751.1 889686 890729 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 889686..890729 Escherichia coli UMN026 7155570 YP_002411590.1 CDS pnuC NC_011751.1 890767 891486 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 219824, 90330519; Product type t : transporter; nicotinamide mononucleotide transporter 890767..891486 Escherichia coli UMN026 7157220 YP_002411591.1 CDS zitB NC_011751.1 891483 892424 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(891483..892424) Escherichia coli UMN026 7157483 YP_002411592.1 CDS ybgS NC_011751.1 892538 892918 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(892538..892918) Escherichia coli UMN026 7159686 YP_002411593.1 CDS aroG NC_011751.1 893234 894286 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 893234..894286 Escherichia coli UMN026 7158432 YP_002411594.1 CDS gpmA NC_011751.1 894452 895204 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(894452..895204) Escherichia coli UMN026 7155789 YP_002411595.1 CDS galM NC_011751.1 895407 896447 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(895407..896447) Escherichia coli UMN026 7156604 YP_002411596.1 CDS galK NC_011751.1 896441 897589 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(896441..897589) Escherichia coli UMN026 7156496 YP_002411597.1 CDS galT NC_011751.1 897593 898639 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(897593..898639) Escherichia coli UMN026 7156495 YP_002411598.1 CDS galE NC_011751.1 898649 899665 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89274199, 92253563, 92338916, 3022232, 6301942, 8564363, 8611559, 8931134, 9174344, 9271499, 9708982; Product type e : enzyme; UDP-galactose-4-epimerase complement(898649..899665) Escherichia coli UMN026 7156500 YP_002411599.1 CDS modF NC_011751.1 899928 901400 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF complement(899928..901400) Escherichia coli UMN026 7156493 YP_002411600.1 CDS ECUMN_0845 NC_011751.1 901328 901474 R Evidence 6 : Doubtful CDS; hypothetical protein complement(901328..901474) Escherichia coli UMN026 7157157 YP_002411601.1 CDS modE NC_011751.1 901468 902256 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(901468..902256) Escherichia coli UMN026 7154761 YP_002411602.1 CDS ybhT NC_011751.1 902385 902534 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 902385..902534 Escherichia coli UMN026 7157156 YP_002411603.1 CDS modA NC_011751.1 902701 903474 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 902701..903474 Escherichia coli UMN026 7158450 YP_002411604.1 CDS modB NC_011751.1 903474 904163 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease protein 903474..904163 Escherichia coli UMN026 7157152 YP_002411605.1 CDS modC NC_011751.1 904166 905224 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 904166..905224 Escherichia coli UMN026 7157153 YP_002411606.1 CDS ybhA NC_011751.1 905225 906043 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(905225..906043) Escherichia coli UMN026 7157154 YP_002411607.1 CDS pgl NC_011751.1 906198 907193 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 906198..907193 Escherichia coli UMN026 7158433 YP_002411608.1 CDS ybhD NC_011751.1 907234 908250 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(907234..908250) Escherichia coli UMN026 7157428 YP_002411609.1 CDS ybhH NC_011751.1 908371 909423 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 908371..909423 Escherichia coli UMN026 7158436 YP_002411610.1 CDS ybhI NC_011751.1 909499 910932 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative anion transporter 909499..910932 Escherichia coli UMN026 7158439 YP_002411611.1 CDS ybhJ NC_011751.1 911115 913376 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11782506; Product type pe : putative enzyme; hypothetical protein 911115..913376 Escherichia coli UMN026 7158440 YP_002411612.1 CDS ybhC NC_011751.1 913517 914800 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase complement(913517..914800) Escherichia coli UMN026 7158441 YP_002411613.1 CDS int NC_011751.1 914935 916005 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6446713; Product type h : extrachromosomal origin; Integrase from phage complement(914935..916005) Escherichia coli UMN026 7158435 YP_002411614.1 CDS yfdT NC_011751.1 916316 916660 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(916316..916660) Escherichia coli UMN026 7156838 YP_002411615.1 CDS ECUMN_0860 NC_011751.1 916657 917535 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phosphoadenosine phosphosulfate reductase from phage origin complement(916657..917535) Escherichia coli UMN026 7158928 YP_002411616.1 CDS yfdR NC_011751.1 917526 918062 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(917526..918062) Escherichia coli UMN026 7154762 YP_002411617.1 CDS yfdQ NC_011751.1 918190 919014 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(918190..919014) Escherichia coli UMN026 7158927 YP_002411618.1 CDS yfdP NC_011751.1 919080 919442 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(919080..919442) Escherichia coli UMN026 7158926 YP_002411619.1 CDS ECUMN_0864 NC_011751.1 919515 919739 D Evidence 6 : Doubtful CDS; hypothetical protein 919515..919739 Escherichia coli UMN026 7158925 YP_002411620.1 CDS ECUMN_0865 NC_011751.1 919911 920345 D Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 919911..920345 Escherichia coli UMN026 7154763 YP_002411621.1 CDS ECUMN_0866 NC_011751.1 920317 920538 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(920317..920538) Escherichia coli UMN026 7154764 YP_002411622.1 CDS ECUMN_0867 NC_011751.1 920871 921563 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative transcriptional regulator from phage origin complement(920871..921563) Escherichia coli UMN026 7154765 YP_002411623.1 CDS ECUMN_0868 NC_011751.1 921661 921921 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative lambda repressor-like DNA-binding domain-containing protein 921661..921921 Escherichia coli UMN026 7154766 YP_002411624.1 CDS ymfL NC_011751.1 921914 922465 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative nucleic acid-binding protein; e14 prophage 921914..922465 Escherichia coli UMN026 7154767 YP_002411625.1 CDS ymfM NC_011751.1 922462 922800 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 922462..922800 Escherichia coli UMN026 7159482 YP_002411626.1 CDS ECUMN_0872 NC_011751.1 922810 923751 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage replication protein O 922810..923751 Escherichia coli UMN026 7159483 YP_002411627.1 CDS yfdN NC_011751.1 923748 924236 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 923748..924236 Escherichia coli UMN026 7154768 YP_002411628.1 CDS ECUMN_0874 NC_011751.1 924203 924562 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 924203..924562 Escherichia coli UMN026 7158924 YP_002411629.1 CDS rusA NC_011751.1 924559 924948 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Crossover junction endodeoxyribonuclease 924559..924948 Escherichia coli UMN026 7154769 YP_002411630.1 CDS ECUMN_0876 NC_011751.1 924866 925777 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 924866..925777 Escherichia coli UMN026 7157820 YP_002411631.1 CDS ECUMN_0877 NC_011751.1 925779 926774 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 925779..926774 Escherichia coli UMN026 7154770 YP_002411632.1 CDS Q NC_011751.1 926792 927148 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; antitermination protein from phage origin 926792..927148 Escherichia coli UMN026 7154771 YP_002411633.1 CDS ECUMN_0879 NC_011751.1 927128 928342 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(927128..928342) Escherichia coli UMN026 7157606 YP_002411634.1 CDS ECUMN_0880 NC_011751.1 928345 929520 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(928345..929520) Escherichia coli UMN026 7154772 YP_002411635.1 CDS ECUMN_0881 NC_011751.1 929542 929694 D Evidence 6 : Doubtful CDS; hypothetical protein 929542..929694 Escherichia coli UMN026 7154773 YP_002411636.1 CDS S NC_011751.1 929812 930138 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2998005; Product type h : extrachromosomal origin; Holin 929812..930138 Escherichia coli UMN026 7154774 YP_002411637.1 CDS r NC_011751.1 930142 930618 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; lysozyme inhibitor 930142..930618 Escherichia coli UMN026 7157863 YP_002411638.1 CDS ECUMN_0884 NC_011751.1 930602 930994 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Rz lytic protein from phage origin 930602..930994 Escherichia coli UMN026 7157615 YP_002411639.1 CDS ECUMN_0885 NC_011751.1 930813 931136 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Rz1 lytic protein from bacteriophage origin 930813..931136 Escherichia coli UMN026 7154775 YP_002411640.1 CDS ECUMN_0886 NC_011751.1 931176 931481 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(931176..931481) Escherichia coli UMN026 7154776 YP_002411641.1 CDS ECUMN_0887 NC_011751.1 931555 931905 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative endonuclease 931555..931905 Escherichia coli UMN026 7154777 YP_002411642.1 CDS ECUMN_0888 NC_011751.1 932022 932525 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage terminase, small subunit 932022..932525 Escherichia coli UMN026 7154778 YP_002411643.1 CDS ECUMN_0889 NC_011751.1 932522 934255 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage terminase 932522..934255 Escherichia coli UMN026 7154779 YP_002411644.1 CDS ymfR NC_011751.1 934267 934449 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 934267..934449 Escherichia coli UMN026 7154780 YP_002411645.1 CDS ECUMN_0891 NC_011751.1 934449 935690 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage portal protein 934449..935690 Escherichia coli UMN026 7159485 YP_002411646.1 CDS ECUMN_0892 NC_011751.1 935632 936318 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage pro-head protease 935632..936318 Escherichia coli UMN026 7154781 YP_002411647.1 CDS ECUMN_0893 NC_011751.1 936333 937538 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative major capsid protein 936333..937538 Escherichia coli UMN026 7154782 YP_002411648.1 CDS ECUMN_0894 NC_011751.1 937587 937787 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 937587..937787 Escherichia coli UMN026 7154783 YP_002411649.1 CDS ECUMN_0895 NC_011751.1 937790 938113 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 937790..938113 Escherichia coli UMN026 7154784 YP_002411650.1 CDS ECUMN_0896 NC_011751.1 938110 938520 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage head-tail adaptor 938110..938520 Escherichia coli UMN026 7154785 YP_002411651.1 CDS ECUMN_0897 NC_011751.1 938495 939001 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 938495..939001 Escherichia coli UMN026 7154786 YP_002411652.1 CDS ECUMN_0898 NC_011751.1 938998 939558 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 938998..939558 Escherichia coli UMN026 7154787 YP_002411653.1 CDS ECUMN_0899 NC_011751.1 939567 939737 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 939567..939737 Escherichia coli UMN026 7154788 YP_002411654.1 CDS ECUMN_0900 NC_011751.1 939721 941217 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail sheath protein 939721..941217 Escherichia coli UMN026 7154789 YP_002411655.1 CDS ECUMN_0901 NC_011751.1 941217 941573 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage tail protein 941217..941573 Escherichia coli UMN026 7154790 YP_002411656.1 CDS ECUMN_0902 NC_011751.1 941570 941893 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 941570..941893 Escherichia coli UMN026 7154791 YP_002411657.1 CDS ECUMN_0903 NC_011751.1 941978 943885 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage tail tape measure protein 941978..943885 Escherichia coli UMN026 7154792 YP_002411658.1 CDS ECUMN_0904 NC_011751.1 943910 945286 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail/DNA circulation protein 943910..945286 Escherichia coli UMN026 7154793 YP_002411659.1 CDS ECUMN_0905 NC_011751.1 945283 946362 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail protein 945283..946362 Escherichia coli UMN026 7154794 YP_002411660.1 CDS ECUMN_0906 NC_011751.1 946362 946910 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative baseplate assembly phage protein 946362..946910 Escherichia coli UMN026 7154795 YP_002411661.1 CDS ECUMN_0907 NC_011751.1 946907 947335 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail protein 946907..947335 Escherichia coli UMN026 7154796 YP_002411662.1 CDS ECUMN_0908 NC_011751.1 947322 948380 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative baseplate J-like phage protein 947322..948380 Escherichia coli UMN026 7154797 YP_002411663.1 CDS ymfQ NC_011751.1 948371 948955 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 948371..948955 Escherichia coli UMN026 7154798 YP_002411664.1 CDS ECUMN_0910 NC_011751.1 948959 949891 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; putative carbohydrate kinase; bacteriophage origin 948959..949891 Escherichia coli UMN026 7159484 YP_002411665.1 CDS ECUMN_0911 NC_011751.1 949892 950296 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 949892..950296 Escherichia coli UMN026 7154799 YP_002411666.1 CDS ECUMN_0912 NC_011751.1 950598 952085 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(950598..952085) Escherichia coli UMN026 7154800 YP_002411667.1 CDS yfdH NC_011751.1 952072 953001 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol glucosyl transferase; CPS-53 (KpLE1) prophage complement(952072..953001) Escherichia coli UMN026 7154801 YP_002411668.1 CDS yfdG NC_011751.1 952998 953360 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol-linked glucose translocase (flippase) ; CPS-53 (KpLE1) prophage complement(952998..953360) Escherichia coli UMN026 7158923 YP_002411669.1 CDS ybhB NC_011751.1 953809 954285 R YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein complement(953809..954285) Escherichia coli UMN026 7158922 YP_002411670.1 CDS bioA NC_011751.1 954344 955633 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(954344..955633) Escherichia coli UMN026 7158434 YP_002411671.1 CDS bioB NC_011751.1 955720 956760 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11834738, 12475249, 14704425, 14967041, 20250955, 89066784, 94170810, 94190882, 97382445, 11686925; Product type e : enzyme; biotin synthase 955720..956760 Escherichia coli UMN026 7155876 YP_002411672.1 CDS bioF NC_011751.1 956757 957911 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 956757..957911 Escherichia coli UMN026 7155877 YP_002411673.1 CDS bioC NC_011751.1 957898 958653 D putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 957898..958653 Escherichia coli UMN026 7155880 YP_002411674.1 CDS bioD NC_011751.1 958646 959323 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 958646..959323 Escherichia coli UMN026 7155878 YP_002411675.1 CDS uvrB NC_011751.1 959902 961923 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 959902..961923 Escherichia coli UMN026 7155879 YP_002411676.1 CDS ybhK NC_011751.1 962070 962978 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16272399; Product type pe : putative enzyme; putative transferase complement(962070..962978) Escherichia coli UMN026 7158199 YP_002411677.1 CDS ECUMN_0923 NC_011751.1 963221 963376 R Evidence 6 : Doubtful CDS; hypothetical protein complement(963221..963376) Escherichia coli UMN026 7158442 YP_002411678.1 CDS moaA NC_011751.1 963375 964364 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 963375..964364 Escherichia coli UMN026 7154802 YP_002411679.1 CDS moaB NC_011751.1 964386 964898 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93368423; Product type pf : putative factor; molybdopterin biosynthesis protein B 964386..964898 Escherichia coli UMN026 7157145 YP_002411680.1 CDS moaC NC_011751.1 964901 965386 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 964901..965386 Escherichia coli UMN026 7157146 YP_002411681.1 CDS moaD NC_011751.1 965379 965624 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 965379..965624 Escherichia coli UMN026 7157147 YP_002411682.1 CDS moaE NC_011751.1 965626 966078 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 965626..966078 Escherichia coli UMN026 7157148 YP_002411683.1 CDS ybhL NC_011751.1 966215 966919 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 966215..966919 Escherichia coli UMN026 7157149 YP_002411684.1 CDS ECUMN_0931 NC_011751.1 967124 967513 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 967124..967513 Escherichia coli UMN026 7158443 YP_002411685.1 CDS ybhN NC_011751.1 967549 968505 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(967549..968505) Escherichia coli UMN026 7154803 YP_002411686.1 CDS ybhO NC_011751.1 968505 969746 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20102623, 10634942; Product type e : enzyme; cardiolipin synthase 2 complement(968505..969746) Escherichia coli UMN026 7158444 YP_002411687.1 CDS ybhP NC_011751.1 969743 970504 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal-dependent hydrolase complement(969743..970504) Escherichia coli UMN026 7158445 YP_002411688.1 CDS ybhQ NC_011751.1 970637 971047 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 970637..971047 Escherichia coli UMN026 7158446 YP_002411689.1 CDS ybhR NC_011751.1 971009 972115 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease complement(971009..972115) Escherichia coli UMN026 7158447 YP_002411690.1 CDS ybhS NC_011751.1 972126 973259 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease complement(972126..973259) Escherichia coli UMN026 7158448 YP_002411691.1 CDS ybhF NC_011751.1 973252 974988 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein complement(973252..974988) Escherichia coli UMN026 7158449 YP_002411692.1 CDS ybhG NC_011751.1 974981 975979 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16092522; Product type pt : putative transporter; hypothetical protein complement(974981..975979) Escherichia coli UMN026 7158437 YP_002411693.1 CDS ybiH NC_011751.1 975979 976650 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(975979..976650) Escherichia coli UMN026 7158438 YP_002411694.1 CDS rhlE NC_011751.1 976879 978243 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 976879..978243 Escherichia coli UMN026 7158454 YP_002411695.1 CDS ybiA NC_011751.1 978479 978961 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(978479..978961) Escherichia coli UMN026 7157676 YP_002411696.1 CDS dinG NC_011751.1 979081 981231 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 979081..981231 Escherichia coli UMN026 7158451 YP_002411697.1 CDS ybiB NC_011751.1 981259 982221 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; glycosyl transferase family protein 981259..982221 Escherichia coli UMN026 7156169 YP_002411698.1 CDS ybiC NC_011751.1 982362 983447 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8405966; Product type pe : putative enzyme; hypothetical protein 982362..983447 Escherichia coli UMN026 7158452 YP_002411699.1 CDS ybiJ NC_011751.1 983676 983936 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(983676..983936) Escherichia coli UMN026 7158453 YP_002411700.1 CDS ybiI NC_011751.1 984201 984467 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(984201..984467) Escherichia coli UMN026 7158456 YP_002411701.1 CDS ybiX NC_011751.1 984541 985218 R Evidence 4 : Homologs of previously reported genes of unknown function; putative hydroxylase complement(984541..985218) Escherichia coli UMN026 7158455 YP_002411702.1 CDS fiu NC_011751.1 985260 987542 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(985260..987542) Escherichia coli UMN026 7158467 YP_002411703.1 CDS ybiM NC_011751.1 987807 988211 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(987807..988211) Escherichia coli UMN026 7156367 YP_002411704.1 CDS ybiN NC_011751.1 988343 989269 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative SAM-dependent methyltransferase 988343..989269 Escherichia coli UMN026 7158457 YP_002411705.1 CDS ybiO NC_011751.1 989266 991491 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein complement(989266..991491) Escherichia coli UMN026 7158458 YP_002411706.1 CDS glnQ NC_011751.1 991752 992474 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(991752..992474) Escherichia coli UMN026 7158459 YP_002411707.1 CDS glnP NC_011751.1 992471 993130 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease protein complement(992471..993130) Escherichia coli UMN026 7156557 YP_002411708.1 CDS glnH NC_011751.1 993269 994015 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(993269..994015) Escherichia coli UMN026 7156556 YP_002411709.1 CDS dps NC_011751.1 994419 994922 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(994419..994922) Escherichia coli UMN026 7156553 YP_002411710.1 CDS rhtA NC_011751.1 995221 996108 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12648727, 8021175; Product type t : transporter; threonine and homoserine efflux system complement(995221..996108) Escherichia coli UMN026 7156200 YP_002411711.1 CDS ompX NC_011751.1 996461 996976 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 996461..996976 Escherichia coli UMN026 7157679 YP_002411712.1 CDS ybiP NC_011751.1 997025 998608 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16514146; Product type pe : putative enzyme; hypothetical protein complement(997025..998608) Escherichia coli UMN026 7157352 YP_002411713.1 CDS ECUMN_0960 NC_011751.1 999459 1000040 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 999459..1000040 Escherichia coli UMN026 7157833 YP_002411714.1 CDS int NC_011751.1 1000061 1001116 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3806670; Product type h : extrachromosomal origin; Integrase from bacteriophage origin complement(1000061..1001116) Escherichia coli UMN026 7154804 YP_002411715.1 CDS cI NC_011751.1 1001118 1001699 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2370665; Product type h : extrachromosomal origin; repressor protein from bacteriophage origin complement(1001118..1001699) Escherichia coli UMN026 7156839 YP_002411716.1 CDS ECUMN_0963 NC_011751.1 1001835 1002056 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative regulator from bacteriophage origin 1001835..1002056 Escherichia coli UMN026 7155962 YP_002411717.1 CDS cII NC_011751.1 1002087 1002590 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; regulatory protein from bacteriophage origin 1002087..1002590 Escherichia coli UMN026 7154805 YP_002411718.1 CDS ECUMN_0965 NC_011751.1 1002600 1002773 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1002600..1002773 Escherichia coli UMN026 7155964 YP_002411719.1 CDS ECUMN_0966 NC_011751.1 1002782 1003210 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1002782..1003210 Escherichia coli UMN026 7154806 YP_002411720.1 CDS ECUMN_0967 NC_011751.1 1003210 1003611 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1003210..1003611 Escherichia coli UMN026 7154807 YP_002411721.1 CDS ECUMN_0968 NC_011751.1 1003679 1003912 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1003679..1003912 Escherichia coli UMN026 7154808 YP_002411722.1 CDS ECUMN_0969 NC_011751.1 1003903 1004772 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; adenine-specific DNA-methyltransferase 1003903..1004772 Escherichia coli UMN026 7154809 YP_002411723.1 CDS ECUMN_0970 NC_011751.1 1004769 1004981 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1004769..1004981 Escherichia coli UMN026 7154810 YP_002411724.1 CDS A NC_011751.1 1004947 1006998 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2352277; Product type h : extrachromosomal origin; replication gene A protein from bacteriophage origin 1004947..1006998 Escherichia coli UMN026 7154811 YP_002411725.1 CDS ECUMN_0972 NC_011751.1 1007118 1007324 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1007118..1007324 Escherichia coli UMN026 7155653 YP_002411726.1 CDS ECUMN_0973 NC_011751.1 1007298 1007621 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1007298..1007621) Escherichia coli UMN026 7154812 YP_002411727.1 CDS Q NC_011751.1 1007618 1008679 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative portal vertex protein from bacteriophage origin complement(1007618..1008679) Escherichia coli UMN026 7154813 YP_002411728.1 CDS P NC_011751.1 1008676 1010451 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Terminase, ATPase subunit from bacteriophage origin complement(1008676..1010451) Escherichia coli UMN026 7157607 YP_002411729.1 CDS ECUMN_0976 NC_011751.1 1010613 1011416 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1837355; Product type h : extrachromosomal origin; putative capsid scaffolding protein from bacteriophage origin 1010613..1011416 Escherichia coli UMN026 7157372 YP_002411730.1 CDS ECUMN_0977 NC_011751.1 1011478 1012500 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8874520; Product type h : extrachromosomal origin; putative major capsid protein from phage origin 1011478..1012500 Escherichia coli UMN026 7154814 YP_002411731.1 CDS ECUMN_0978 NC_011751.1 1012504 1013205 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1837355; Product type h : extrachromosomal origin; putative terminase, endonuclease subunit from bacteriophage origin 1012504..1013205 Escherichia coli UMN026 7154815 YP_002411732.1 CDS ECUMN_0979 NC_011751.1 1013251 1013754 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Head completion/stabilization protein (GpL) from bacteriophage origin 1013251..1013754 Escherichia coli UMN026 7154816 YP_002411733.1 CDS ECUMN_0980 NC_011751.1 1013751 1014257 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1013751..1014257 Escherichia coli UMN026 7154817 YP_002411734.1 CDS ECUMN_0981 NC_011751.1 1014254 1014961 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1014254..1014961 Escherichia coli UMN026 7154818 YP_002411735.1 CDS ECUMN_0982 NC_011751.1 1014958 1016085 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail sheath protein from bacteriophage origin 1014958..1016085 Escherichia coli UMN026 7154819 YP_002411736.1 CDS ECUMN_0983 NC_011751.1 1016082 1016537 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail tube protein from bacteriophage origin 1016082..1016537 Escherichia coli UMN026 7154820 YP_002411737.1 CDS ECUMN_0984 NC_011751.1 1016548 1016850 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8051010; Product type h : extrachromosomal origin; Holin from bacteriophage origin 1016548..1016850 Escherichia coli UMN026 7154821 YP_002411738.1 CDS ECUMN_0985 NC_011751.1 1016837 1017178 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1016837..1017178 Escherichia coli UMN026 7154822 YP_002411739.1 CDS ECUMN_0986 NC_011751.1 1017178 1017558 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1017178..1017558 Escherichia coli UMN026 7154823 YP_002411740.1 CDS ECUMN_0987 NC_011751.1 1017654 1017920 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1017654..1017920 Escherichia coli UMN026 7154824 YP_002411741.1 CDS ECUMN_0988 NC_011751.1 1018108 1020168 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail tape measure protein from bacteriophage origin 1018108..1020168 Escherichia coli UMN026 7154825 YP_002411742.1 CDS ECUMN_0989 NC_011751.1 1020165 1020494 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1020165..1020494 Escherichia coli UMN026 7154826 YP_002411743.1 CDS ECUMN_0990 NC_011751.1 1020491 1021675 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1020491..1021675 Escherichia coli UMN026 7154827 YP_002411744.1 CDS ECUMN_0991 NC_011751.1 1021662 1022255 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1021662..1022255 Escherichia coli UMN026 7154828 YP_002411745.1 CDS ECUMN_0992 NC_011751.1 1022266 1024314 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1022266..1024314 Escherichia coli UMN026 7154829 YP_002411746.1 CDS ECUMN_0993 NC_011751.1 1024281 1024733 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber assembly protein from bacteriophage origin 1024281..1024733 Escherichia coli UMN026 7154830 YP_002411747.1 CDS ECUMN_0994 NC_011751.1 1024723 1025448 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1024723..1025448 Escherichia coli UMN026 7154831 YP_002411748.1 CDS ECUMN_0995 NC_011751.1 1025420 1025965 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1025420..1025965 Escherichia coli UMN026 7154832 YP_002411749.1 CDS ECUMN_0996 NC_011751.1 1025965 1027668 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1025965..1027668 Escherichia coli UMN026 7154833 YP_002411750.1 CDS ECUMN_0997 NC_011751.1 1028213 1028437 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(1028213..1028437) Escherichia coli UMN026 7154834 YP_002411751.1 CDS ECUMN_0998 NC_011751.1 1028376 1029014 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(1028376..1029014) Escherichia coli UMN026 7154835 YP_002411752.1 CDS ECUMN_0999 NC_011751.1 1029060 1029323 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(1029060..1029323) Escherichia coli UMN026 7154836 YP_002411753.1 CDS ECUMN_1000 NC_011751.1 1029361 1029960 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1029361..1029960) Escherichia coli UMN026 7154837 YP_002411754.1 CDS mntR NC_011751.1 1030164 1030631 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 1030164..1030631 Escherichia coli UMN026 7154838 YP_002411755.1 CDS ybiR NC_011751.1 1030628 1031746 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 1030628..1031746 Escherichia coli UMN026 7157144 YP_002411756.1 CDS ybiS NC_011751.1 1031804 1032724 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10493123, 9298646; hypothetical protein complement(1031804..1032724) Escherichia coli UMN026 7158461 YP_002411757.1 CDS ybiT NC_011751.1 1032943 1034538 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11916677; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 1032943..1034538 Escherichia coli UMN026 7158462 YP_002411758.1 CDS ECUMN_1005 NC_011751.1 1034718 1037093 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glucosidase complement(1034718..1037093) Escherichia coli UMN026 7158463 YP_002411759.1 CDS ECUMN_1006 NC_011751.1 1037096 1038403 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12795379; Product type pt : putative transporter; putative hexuronate transporter complement(1037096..1038403) Escherichia coli UMN026 7154839 YP_002411760.1 CDS ECUMN_1007 NC_011751.1 1038437 1038589 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1038437..1038589) Escherichia coli UMN026 7154840 YP_002411761.1 CDS ECUMN_1008 NC_011751.1 1038614 1039795 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative transcriptional regulator 1038614..1039795 Escherichia coli UMN026 7154841 YP_002411762.1 CDS ybiU NC_011751.1 1039762 1041027 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1039762..1041027) Escherichia coli UMN026 7154842 YP_002411763.1 CDS ybiV NC_011751.1 1041179 1041994 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15657928; Product type e : enzyme; type II HAD phosphatase complement(1041179..1041994) Escherichia coli UMN026 7158464 YP_002411764.1 CDS ybiW NC_011751.1 1042140 1044572 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16218870; Product type pe : putative enzyme; putative glycyl radical cofactor protein complement(1042140..1044572) Escherichia coli UMN026 7158465 YP_002411765.1 CDS ybiY NC_011751.1 1044578 1045504 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15581584; Product type pe : putative enzyme; putative AdoMet-dependent glycyl radical activating enzyme complement(1044578..1045504) Escherichia coli UMN026 7158466 YP_002411766.1 CDS fsaA NC_011751.1 1045608 1046270 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 1045608..1046270 Escherichia coli UMN026 7158468 YP_002411767.1 CDS moeB NC_011751.1 1046346 1047095 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(1046346..1047095) Escherichia coli UMN026 7156452 YP_002411768.1 CDS moeA NC_011751.1 1047095 1048330 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(1047095..1048330) Escherichia coli UMN026 7157159 YP_002411769.1 CDS iaaA NC_011751.1 1048534 1049499 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15159592, 20508248, 3045084, 7984428; Product type e : enzyme; L-asparaginase 1048534..1049499 Escherichia coli UMN026 7157158 YP_002411770.1 CDS yliA NC_011751.1 1049519 1051357 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 1049519..1051357 Escherichia coli UMN026 7156777 YP_002411771.1 CDS yliB NC_011751.1 1051377 1052915 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pt : putative transporter; putative peptide ABC transporter periplasmic-binding protein 1051377..1052915 Escherichia coli UMN026 7159463 YP_002411772.1 CDS yliC NC_011751.1 1052933 1053853 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative peptide ABC transporter permease 1052933..1053853 Escherichia coli UMN026 7159464 YP_002411773.1 CDS yliD NC_011751.1 1053856 1054767 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative peptide ABC transporter permease 1053856..1054767 Escherichia coli UMN026 7159465 YP_002411774.1 CDS yliE NC_011751.1 1054945 1057293 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1054945..1057293 Escherichia coli UMN026 7159466 YP_002411775.1 CDS yliF NC_011751.1 1057301 1058629 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pe : putative enzyme; putative diguanylate cyclase 1057301..1058629 Escherichia coli UMN026 7159467 YP_002411776.1 CDS ECUMN_1023 NC_011751.1 1058699 1059028 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1058699..1059028) Escherichia coli UMN026 7159468 YP_002411777.1 CDS ECUMN_1024 NC_011751.1 1059018 1059404 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1059018..1059404) Escherichia coli UMN026 7154843 YP_002411778.1 CDS rimO NC_011751.1 1059630 1060955 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(1059630..1060955) Escherichia coli UMN026 7154844 YP_002411779.1 CDS bssR NC_011751.1 1061168 1061551 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1061168..1061551 Escherichia coli UMN026 7159469 YP_002411780.1 CDS yliI NC_011751.1 1061662 1062777 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16522795, 16864586; Product type e : enzyme; PQQ-dependent aldose sugar dehydrogenase (asd) 1061662..1062777 Escherichia coli UMN026 7155892 YP_002411781.1 CDS yliJ NC_011751.1 1062774 1063400 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(1062774..1063400) Escherichia coli UMN026 7159470 YP_002411782.1 CDS dacC NC_011751.1 1063647 1064849 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 1063647..1064849 Escherichia coli UMN026 7159471 YP_002411783.1 CDS deoR NC_011751.1 1064896 1065654 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89231635, 89336786, 92231401, 2994018; Product type r : regulator; DNA-binding transcriptional repressor DeoR complement(1064896..1065654) Escherichia coli UMN026 7156101 YP_002411784.1 CDS ybjG NC_011751.1 1065712 1066308 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase complement(1065712..1066308) Escherichia coli UMN026 7156144 YP_002411785.1 CDS cmr NC_011751.1 1066593 1067825 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10022825, 12578981, 14688269, 21217867, 21450803, 9079913, 9644262, 99030337, 8655497; Product type t : transporter; multidrug efflux system protein 1066593..1067825 Escherichia coli UMN026 7158472 YP_002411786.1 CDS ybjH NC_011751.1 1067866 1068150 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1067866..1068150) Escherichia coli UMN026 7155985 YP_002411787.1 CDS ybjI NC_011751.1 1068235 1069050 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme; putative phosphatase complement(1068235..1069050) Escherichia coli UMN026 7158473 YP_002411788.1 CDS ybjJ NC_011751.1 1069050 1070258 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(1069050..1070258) Escherichia coli UMN026 7158474 YP_002411789.1 CDS ybjK NC_011751.1 1070342 1070878 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1070342..1070878 Escherichia coli UMN026 7158475 YP_002411790.1 CDS ybjL NC_011751.1 1071053 1072738 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein complement(1071053..1072738) Escherichia coli UMN026 7157834 YP_002411791.1 CDS ybjM NC_011751.1 1073008 1073385 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1073008..1073385 Escherichia coli UMN026 7158477 YP_002411792.1 CDS grxA NC_011751.1 1073415 1073672 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 complement(1073415..1073672) Escherichia coli UMN026 7158478 YP_002411793.1 CDS ybjC NC_011751.1 1073832 1074119 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 1073832..1074119 Escherichia coli UMN026 7156614 YP_002411794.1 CDS nfsA NC_011751.1 1074103 1074825 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1074103..1074825 Escherichia coli UMN026 7158469 YP_002411795.1 CDS rimK NC_011751.1 1074886 1075788 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1074886..1075788 Escherichia coli UMN026 7157270 YP_002411796.1 CDS ybjN NC_011751.1 1075876 1076352 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1075876..1076352 Escherichia coli UMN026 7157693 YP_002411797.1 CDS potF NC_011751.1 1076703 1077815 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992, 9651355, 9298646, 8416922; Product type t : transporter; putrescine ABC transporter periplasmic-binding protein 1076703..1077815 Escherichia coli UMN026 7158479 YP_002411798.1 CDS potG NC_011751.1 1077910 1079043 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding subunit 1077910..1079043 Escherichia coli UMN026 7157491 YP_002411799.1 CDS potH NC_011751.1 1079053 1079997 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1079053..1079997 Escherichia coli UMN026 7157492 YP_002411800.1 CDS potI NC_011751.1 1079994 1080839 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1079994..1080839 Escherichia coli UMN026 7157493 YP_002411801.1 CDS ybjO NC_011751.1 1080899 1081387 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1080899..1081387 Escherichia coli UMN026 7157494 YP_002411802.1 CDS rumB NC_011751.1 1081428 1082555 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1081428..1082555 Escherichia coli UMN026 7158480 YP_002411803.1 CDS ECUMN_1050 NC_011751.1 1082836 1084179 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1082836..1084179 Escherichia coli UMN026 7157818 YP_002411804.1 CDS ECUMN_1051 NC_011751.1 1084201 1084521 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase enzyme II, B component 1084201..1084521 Escherichia coli UMN026 7154845 YP_002411805.1 CDS ECUMN_1052 NC_011751.1 1084534 1086015 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfatase 1084534..1086015 Escherichia coli UMN026 7154846 YP_002411806.1 CDS artJ NC_011751.1 1086066 1086797 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422; Product type t : transporter; arginine ABC transporter periplasmic-binding protein complement(1086066..1086797) Escherichia coli UMN026 7154847 YP_002411807.1 CDS artM NC_011751.1 1087023 1087691 R with ArtPQJI acts to transport arginine across the inner membrane; arginine permease ArtM complement(1087023..1087691) Escherichia coli UMN026 7155802 YP_002411808.1 CDS artQ NC_011751.1 1087691 1088407 R with ArtPMJI transports arginine across the inner membrane; arginine permease ArtQ complement(1087691..1088407) Escherichia coli UMN026 7155803 YP_002411809.1 CDS artI NC_011751.1 1088414 1089145 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422, 9740056; Product type t : transporter; arginine ABC transporter periplasmic-binding protein complement(1088414..1089145) Escherichia coli UMN026 7155805 YP_002411810.1 CDS artP NC_011751.1 1089163 1089891 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(1089163..1089891) Escherichia coli UMN026 7155801 YP_002411811.1 CDS ybjP NC_011751.1 1090109 1090624 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein complement(1090109..1090624) Escherichia coli UMN026 7155804 YP_002411812.1 CDS ECUMN_1059 NC_011751.1 1090638 1090820 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1090638..1090820) Escherichia coli UMN026 7158481 YP_002411813.1 CDS ECUMN_1060 NC_011751.1 1091239 1093041 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1091239..1093041 Escherichia coli UMN026 7154848 YP_002411814.1 CDS ybjQ NC_011751.1 1093252 1093575 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1093252..1093575 Escherichia coli UMN026 7154849 YP_002411815.1 CDS ybjR NC_011751.1 1093572 1094402 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cell wall amidase and lipoprotein 1093572..1094402 Escherichia coli UMN026 7158482 YP_002411816.1 CDS ybjS NC_011751.1 1094399 1095412 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain complement(1094399..1095412) Escherichia coli UMN026 7158483 YP_002411817.1 CDS ybjT NC_011751.1 1095511 1096941 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1095511..1096941) Escherichia coli UMN026 7158484 YP_002411818.1 CDS ltaE NC_011751.1 1096952 1097953 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(1096952..1097953) Escherichia coli UMN026 7158485 YP_002411819.1 CDS poxB NC_011751.1 1097990 1099708 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(1097990..1099708) Escherichia coli UMN026 7157027 YP_002411820.1 CDS hcr NC_011751.1 1099841 1100809 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20117674; Product type e : enzyme; HCP oxidoreductase, NADH-dependent complement(1099841..1100809) Escherichia coli UMN026 7157496 YP_002411821.1 CDS hcp NC_011751.1 1100821 1102473 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(1100821..1102473) Escherichia coli UMN026 7156642 YP_002411822.1 CDS ybjE NC_011751.1 1102617 1103516 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(1102617..1103516) Escherichia coli UMN026 7156641 YP_002411823.1 CDS aqpZ NC_011751.1 1104000 1104695 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(1104000..1104695) Escherichia coli UMN026 7158471 YP_002411824.1 CDS ybjD NC_011751.1 1105121 1106779 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1105121..1106779 Escherichia coli UMN026 7155756 YP_002411825.1 CDS ybjX NC_011751.1 1106776 1107768 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1106776..1107768) Escherichia coli UMN026 7158470 YP_002411826.1 CDS macA NC_011751.1 1107883 1108998 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1107883..1108998 Escherichia coli UMN026 7158486 YP_002411827.1 CDS macB NC_011751.1 1108995 1110941 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease protein 1108995..1110941 Escherichia coli UMN026 7157037 YP_002411828.1 CDS cspD NC_011751.1 1111013 1111237 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(1111013..1111237) Escherichia coli UMN026 7157038 YP_002411829.1 CDS clpS NC_011751.1 1111560 1111880 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1111560..1111880 Escherichia coli UMN026 7156037 YP_002411830.1 CDS clpA NC_011751.1 1111911 1114187 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1111911..1114187 Escherichia coli UMN026 7155981 YP_002411831.1 CDS ECUMN_1078 NC_011751.1 1114305 1114703 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1114305..1114703) Escherichia coli UMN026 7155978 YP_002411832.1 CDS infA NC_011751.1 1115348 1115566 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1115348..1115566) Escherichia coli UMN026 7155644 YP_002411833.1 CDS aat NC_011751.1 1115851 1116555 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA --protein transferase complement(1115851..1116555) Escherichia coli UMN026 7156811 YP_002411834.1 CDS cydC NC_011751.1 1116597 1118318 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component complement(1116597..1118318) Escherichia coli UMN026 7155665 YP_002411835.1 CDS cydD NC_011751.1 1118319 1120085 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component complement(1118319..1120085) Escherichia coli UMN026 7156067 YP_002411836.1 CDS trxB NC_011751.1 1120208 1121173 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(1120208..1121173) Escherichia coli UMN026 7156068 YP_002411837.1 CDS lrp NC_011751.1 1121719 1122213 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1121719..1122213 Escherichia coli UMN026 7158130 YP_002411838.1 CDS ftsK NC_011751.1 1122348 1126454 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 1122348..1126454 Escherichia coli UMN026 7157018 YP_002411839.1 CDS lolA NC_011751.1 1126610 1127224 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1126610..1127224 Escherichia coli UMN026 7156461 YP_002411840.1 CDS ycaJ NC_011751.1 1127235 1128578 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7567469, 7628437, 11459952, 11029431; Product type cp : cell process; recombination factor protein RarA 1127235..1128578 Escherichia coli UMN026 7156994 YP_002411841.1 CDS serS NC_011751.1 1128669 1129961 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1128669..1129961 Escherichia coli UMN026 7158491 YP_002411842.1 CDS dmsA NC_011751.1 1130200 1132644 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 94171715, 10801884, 3062312; Product type e : enzyme; dimethyl sulfoxide reductase, anaerobic, subunit A 1130200..1132644 Escherichia coli UMN026 7157900 YP_002411843.1 CDS dmsB NC_011751.1 1132655 1133272 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91070067, 91355180, 92011349, 3062312; Product type e : enzyme; dimethyl sulfoxide reductase, anaerobic, subunit B 1132655..1133272 Escherichia coli UMN026 7156179 YP_002411844.1 CDS dmsC NC_011751.1 1133274 1134137 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 3062312, 8429002; Product type e : enzyme; dimethyl sulfoxide reductase, anaerobic, subunit C 1133274..1134137 Escherichia coli UMN026 7156180 YP_002411845.1 CDS ycaC NC_011751.1 1134173 1134799 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9782055, 3062312, 11714269; Product type pe : putative enzyme; putative hydrolase complement(1134173..1134799) Escherichia coli UMN026 7156181 YP_002411846.1 CDS ycaD NC_011751.1 1135114 1136262 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS family transporter protein 1135114..1136262 Escherichia coli UMN026 7158488 YP_002411847.1 CDS ycaM NC_011751.1 1136472 1137902 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pt : putative transporter; putative transporter 1136472..1137902 Escherichia coli UMN026 7158489 YP_002411848.1 CDS pflA NC_011751.1 1138112 1138852 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1138112..1138852) Escherichia coli UMN026 7158493 YP_002411849.1 CDS pflB NC_011751.1 1139044 1141326 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91064082, 92276323, 10504733, 1310545, 2651404, 3053170, 9629924; Product type e : enzyme; pyruvate formate lyase I complement(1139044..1141326) Escherichia coli UMN026 7157421 YP_002411850.1 CDS focA NC_011751.1 1141381 1142238 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293770, 2651404; Product type t : transporter; formate transporter complement(1141381..1142238) Escherichia coli UMN026 7157422 YP_002411851.1 CDS ycaO NC_011751.1 1142644 1144404 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1142644..1144404) Escherichia coli UMN026 7156421 YP_002411852.1 CDS ycaP NC_011751.1 1144534 1145226 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1144534..1145226 Escherichia coli UMN026 7158494 YP_002411853.1 CDS serC NC_011751.1 1145425 1146513 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1145425..1146513 Escherichia coli UMN026 7158495 YP_002411854.1 CDS aroA NC_011751.1 1146584 1147867 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1146584..1147867 Escherichia coli UMN026 7157899 YP_002411855.1 CDS ycaL NC_011751.1 1148037 1148801 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative lipoprotein with metallohydrolase domain 1148037..1148801 Escherichia coli UMN026 7155783 YP_002411856.1 CDS cmk NC_011751.1 1148974 1149657 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1148974..1149657 Escherichia coli UMN026 7158492 YP_002411857.1 CDS rpsA NC_011751.1 1149768 1151441 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1149768..1151441 Escherichia coli UMN026 7155984 YP_002411858.1 CDS ihfB NC_011751.1 1151601 1151885 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1151601..1151885 Escherichia coli UMN026 7157767 YP_002411859.1 CDS ycaI NC_011751.1 1152092 1154356 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1152092..1154356 Escherichia coli UMN026 7156795 YP_002411860.1 CDS msbA NC_011751.1 1154393 1156141 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease protein 1154393..1156141 Escherichia coli UMN026 7158490 YP_002411861.1 CDS lpxK NC_011751.1 1156138 1157124 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1156138..1157124 Escherichia coli UMN026 7157184 YP_002411862.1 CDS ycaQ NC_011751.1 1157161 1158393 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1157161..1158393 Escherichia coli UMN026 7157014 YP_002411863.1 CDS ycaR NC_011751.1 1158445 1158627 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1158445..1158627 Escherichia coli UMN026 7158496 YP_002411864.1 CDS kdsB NC_011751.1 1158624 1159370 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1158624..1159370 Escherichia coli UMN026 7158497 YP_002411865.1 CDS ycbJ NC_011751.1 1159524 1160417 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1159524..1160417 Escherichia coli UMN026 7156896 YP_002411866.1 CDS ycbC NC_011751.1 1160394 1161173 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1160394..1161173) Escherichia coli UMN026 7158501 YP_002411867.1 CDS ECUMN_1114 NC_011751.1 1161076 1161240 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1161076..1161240) Escherichia coli UMN026 7158499 YP_002411868.1 CDS smtA NC_011751.1 1161309 1162094 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 1161309..1162094 Escherichia coli UMN026 7154851 YP_002411869.1 CDS mukF NC_011751.1 1162091 1163413 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1162091..1163413 Escherichia coli UMN026 7157944 YP_002411870.1 CDS mukE NC_011751.1 1163421 1164098 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1163421..1164098 Escherichia coli UMN026 7157200 YP_002411871.1 CDS mukB NC_011751.1 1164098 1168558 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1164098..1168558 Escherichia coli UMN026 7157199 YP_002411872.1 CDS ycbB NC_011751.1 1168819 1170666 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 1168819..1170666 Escherichia coli UMN026 7157198 YP_002411873.1 CDS ycbK NC_011751.1 1170847 1171395 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1170847..1171395 Escherichia coli UMN026 7158498 YP_002411874.1 CDS ycbL NC_011751.1 1171422 1172069 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14529289; Product type pe : putative enzyme; putative metal-binding hydrolase 1171422..1172069 Escherichia coli UMN026 7158502 YP_002411875.1 CDS aspC NC_011751.1 1172120 1173310 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1172120..1173310) Escherichia coli UMN026 7158503 YP_002411876.1 CDS ompF NC_011751.1 1173495 1174583 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(1173495..1174583) Escherichia coli UMN026 7155818 YP_002411877.1 CDS asnC NC_011751.1 1175186 1176586 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1175186..1176586) Escherichia coli UMN026 7157346 YP_002411878.1 CDS pncB NC_011751.1 1176755 1177957 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1176755..1177957) Escherichia coli UMN026 7155816 YP_002411879.1 CDS pepN NC_011751.1 1178223 1180835 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101837, 86164315, 87163509, 2436977, 3018440; Product type e : enzyme; aminopeptidase N 1178223..1180835 Escherichia coli UMN026 7157479 YP_002411880.1 CDS ECUMN_1127 NC_011751.1 1180914 1181444 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 1180914..1181444 Escherichia coli UMN026 7157414 YP_002411881.1 CDS ECUMN_1128 NC_011751.1 1181549 1182271 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 1181549..1182271 Escherichia coli UMN026 7154852 YP_002411882.1 CDS ssuB NC_011751.1 1182477 1183244 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1182477..1183244) Escherichia coli UMN026 7154853 YP_002411883.1 CDS ssuC NC_011751.1 1183241 1184032 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate permease complement(1183241..1184032) Escherichia coli UMN026 7157992 YP_002411884.1 CDS ssuD NC_011751.1 1184044 1185189 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1184044..1185189) Escherichia coli UMN026 7157993 YP_002411885.1 CDS ssuA NC_011751.1 1185186 1186145 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1185186..1186145) Escherichia coli UMN026 7157994 YP_002411886.1 CDS ssuE NC_011751.1 1186138 1186713 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20245523, 99410391, 99436146, 8774726; Product type e : enzyme; NAD(P)H-dependent FMN reductase complement(1186138..1186713) Escherichia coli UMN026 7157991 YP_002411887.1 CDS pyrD NC_011751.1 1186950 1187960 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1186950..1187960 Escherichia coli UMN026 7157995 YP_002411888.1 CDS ycbW NC_011751.1 1188134 1188676 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1188134..1188676 Escherichia coli UMN026 7157599 YP_002411889.1 CDS ycbX NC_011751.1 1188673 1189782 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1327782; Product type pe : putative enzyme; putative 2Fe-2S cluster-containing protein complement(1188673..1189782) Escherichia coli UMN026 7158504 YP_002411890.1 CDS rlmL NC_011751.1 1190026 1192134 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1190026..1192134 Escherichia coli UMN026 7158505 YP_002411891.1 CDS uup NC_011751.1 1192146 1194053 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1192146..1194053 Escherichia coli UMN026 7158506 YP_002411892.1 CDS pqiA NC_011751.1 1194183 1195436 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible membrane protein A 1194183..1195436 Escherichia coli UMN026 7158197 YP_002411893.1 CDS pqiB NC_011751.1 1195441 1197081 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible protein B 1195441..1197081 Escherichia coli UMN026 7157513 YP_002411894.1 CDS ymbA NC_011751.1 1197093 1197641 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1197093..1197641 Escherichia coli UMN026 7157514 YP_002411895.1 CDS rmf NC_011751.1 1197897 1198064 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1101029, 90207255, 2832401, 8440252; Product type f : factor; ribosome modulation factor 1197897..1198064 Escherichia coli UMN026 7159473 YP_002411896.1 CDS fabA NC_011751.1 1198134 1198652 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-(acyl carrier protein) dehydratase complement(1198134..1198652) Escherichia coli UMN026 7157703 YP_002411897.1 CDS ycbZ NC_011751.1 1198721 1200481 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-dependent protease complement(1198721..1200481) Escherichia coli UMN026 7156293 YP_002411898.1 CDS ycbG NC_011751.1 1200667 1201119 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1200667..1201119 Escherichia coli UMN026 7158507 YP_002411899.1 CDS ompA NC_011751.1 1201195 1202235 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1201195..1202235) Escherichia coli UMN026 7158500 YP_002411900.1 CDS ECUMN_1147 NC_011751.1 1202389 1202607 D Evidence 6 : Doubtful CDS; hypothetical protein 1202389..1202607 Escherichia coli UMN026 7157344 YP_002411901.1 CDS sulA NC_011751.1 1202591 1203100 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10368140, 91072263, 93163041, 98348458, 3297925, 6253901, 6306396; Product type cp : cell process; SOS cell division inhibitor complement(1202591..1203100) Escherichia coli UMN026 7156861 YP_002411902.1 CDS yccR NC_011751.1 1203319 1203948 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1203319..1203948 Escherichia coli UMN026 7158011 YP_002411903.1 CDS yccS NC_011751.1 1203911 1206064 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1203911..1206064) Escherichia coli UMN026 7158513 YP_002411904.1 CDS yccF NC_011751.1 1206083 1206529 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1206083..1206529) Escherichia coli UMN026 7158514 YP_002411905.1 CDS helD NC_011751.1 1206652 1208706 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1206652..1208706 Escherichia coli UMN026 7158510 YP_002411906.1 CDS mgsA NC_011751.1 1208738 1209196 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1208738..1209196) Escherichia coli UMN026 7156649 YP_002411907.1 CDS yccT NC_011751.1 1209292 1209954 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1209292..1209954) Escherichia coli UMN026 7157118 YP_002411908.1 CDS yccU NC_011751.1 1210127 1210540 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative CoA-binding protein 1210127..1210540 Escherichia coli UMN026 7158515 YP_002411909.1 CDS yccV NC_011751.1 1210585 1210902 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700277, 15569148; Product type f : factor; heat shock protein HspQ complement(1210585..1210902) Escherichia coli UMN026 7158516 YP_002411910.1 CDS yccW NC_011751.1 1210960 1212063 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AdoMet-dependent methyltransferase, UPF0064 family complement(1210960..1212063) Escherichia coli UMN026 7158517 YP_002411911.1 CDS yccX NC_011751.1 1212032 1212523 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1212032..1212523 Escherichia coli UMN026 7158518 YP_002411912.1 CDS tusE NC_011751.1 1212520 1212849 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1212520..1212849) Escherichia coli UMN026 7158519 YP_002411913.1 CDS yccA NC_011751.1 1212940 1213599 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6376117; Product type m : membrane component; hypothetical protein complement(1212940..1213599) Escherichia coli UMN026 7158146 YP_002411914.1 CDS ECUMN_1161 NC_011751.1 1213801 1213977 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1213801..1213977) Escherichia coli UMN026 7158508 YP_002411915.1 CDS hyaA NC_011751.1 1214320 1215438 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86192450, 90202716, 92215587; Product type e : enzyme; hydrogenase 1, small subunit 1214320..1215438 Escherichia coli UMN026 7155643 YP_002411916.1 CDS hyaB NC_011751.1 1215435 1217228 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1215435..1217228 Escherichia coli UMN026 7156734 YP_002411917.1 CDS hyaC NC_011751.1 1217247 1217954 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type c : carrier; hydrogenase 1 b-type cytochrome subunit 1217247..1217954 Escherichia coli UMN026 7156735 YP_002411918.1 CDS hyaD NC_011751.1 1217951 1218538 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1217951..1218538 Escherichia coli UMN026 7156736 YP_002411919.1 CDS hyaE NC_011751.1 1218535 1218933 D involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1218535..1218933 Escherichia coli UMN026 7156737 YP_002411920.1 CDS hyaF NC_011751.1 1218930 1219787 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type f : factor; protein involved in nickel incorporation into hydrogenase-1 proteins 1218930..1219787 Escherichia coli UMN026 7156738 YP_002411921.1 CDS appC NC_011751.1 1219921 1221465 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase, subunit I 1219921..1221465 Escherichia coli UMN026 7156739 YP_002411922.1 CDS appB NC_011751.1 1221477 1222613 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase, subunit II 1221477..1222613 Escherichia coli UMN026 7155753 YP_002411923.1 CDS appA NC_011751.1 1222810 1224108 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20122624, 92049231, 93054596, 10696472, 2168385, 3038201, 8387749; Product type e : enzyme; phosphoanhydride phosphorylase 1222810..1224108 Escherichia coli UMN026 7155752 YP_002411924.1 CDS cspH NC_011751.1 1224096 1224308 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9484881, 9439003; Product type f : factor; stress protein, member of the CspA-family complement(1224096..1224308) Escherichia coli UMN026 7155751 YP_002411925.1 CDS cspG NC_011751.1 1224594 1224806 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 15466053, 8631696, 9439003; Product type r : regulator; cold shock protein CspG 1224594..1224806 Escherichia coli UMN026 7156041 YP_002411926.1 CDS gnsA NC_011751.1 1225200 1225373 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15317805, 11544213; Product type pr : putative regulator; putative regulator of phosphatidylethanolamine synthesis 1225200..1225373 Escherichia coli UMN026 7156040 YP_002411927.1 CDS yccM NC_011751.1 1225422 1226495 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S membrane protein complement(1225422..1226495) Escherichia coli UMN026 7156593 YP_002411928.1 CDS torS NC_011751.1 1226578 1229430 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1226578..1229430) Escherichia coli UMN026 7158512 YP_002411929.1 CDS torT NC_011751.1 1229393 1230421 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1229393..1230421 Escherichia coli UMN026 7158093 YP_002411930.1 CDS torR NC_011751.1 1230394 1231086 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1230394..1231086) Escherichia coli UMN026 7158094 YP_002411931.1 CDS torC NC_011751.1 1231216 1232388 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293785, 94314186, 99340208, 11056172, 11562502; Product type c : carrier; trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1231216..1232388 Escherichia coli UMN026 7158092 YP_002411932.1 CDS torA NC_011751.1 1232388 1234934 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193091, 90089471, 94293785, 8302830, 8022286; Product type e : enzyme; trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1232388..1234934 Escherichia coli UMN026 7158090 YP_002411933.1 CDS torD NC_011751.1 1234931 1235530 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1234931..1235530 Escherichia coli UMN026 7158089 YP_002411934.1 CDS cbpM NC_011751.1 1235623 1235928 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1235623..1235928) Escherichia coli UMN026 7158091 YP_002411935.1 CDS cbpA NC_011751.1 1235928 1236848 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1235928..1236848) Escherichia coli UMN026 7155923 YP_002411936.1 CDS yccE NC_011751.1 1237108 1238364 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8302830; hypothetical protein 1237108..1238364 Escherichia coli UMN026 7155922 YP_002411937.1 CDS agp NC_011751.1 1238657 1239898 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12455612, 90368616, 91297199, 2153660, 9298646; Product type e : enzyme; glucose-1-phosphatase/inositol phosphatase 1238657..1239898 Escherichia coli UMN026 7158509 YP_002411938.1 CDS yccJ NC_011751.1 1239936 1240163 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1239936..1240163) Escherichia coli UMN026 7155716 YP_002411939.1 CDS wrbA NC_011751.1 1240184 1240780 R stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA complement(1240184..1240780) Escherichia coli UMN026 7158511 YP_002411940.1 CDS ECUMN_1187 NC_011751.1 1240984 1241220 D Evidence 6 : Doubtful CDS; hypothetical protein 1240984..1241220 Escherichia coli UMN026 7158234 YP_002411941.1 CDS ymdF NC_011751.1 1241153 1241326 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1241153..1241326 Escherichia coli UMN026 7154856 YP_002411942.1 CDS rutG NC_011751.1 1241415 1242851 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type t : transporter; pyrimidine transporter complement(1241415..1242851) Escherichia coli UMN026 7159477 YP_002411943.1 CDS rutF NC_011751.1 1242758 1243252 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542, 10633095; Product type e : enzyme; flavin:NADH oxidoreductase subunit of alternative pyrimidine degradation pathway complement(1242758..1243252) Escherichia coli UMN026 7157828 YP_002411944.1 CDS rutE NC_011751.1 1243263 1243853 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; hypothetical protein complement(1243263..1243853) Escherichia coli UMN026 7157827 YP_002411945.1 CDS rutD NC_011751.1 1243850 1244689 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; alternative pyrimidine degradation pathway protein complement(1243850..1244689) Escherichia coli UMN026 7157826 YP_002411946.1 CDS rutC NC_011751.1 1244670 1245056 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; alternative pyrimidine degradation pathway protein complement(1244670..1245056) Escherichia coli UMN026 7157825 YP_002411947.1 CDS rutB NC_011751.1 1245068 1245760 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; alternative pyrimidine degradation pathway protein complement(1245068..1245760) Escherichia coli UMN026 7157824 YP_002411948.1 CDS rutA NC_011751.1 1245760 1246908 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; monooxygenase of the alternative pyrimidine degradation pathway complement(1245760..1246908) Escherichia coli UMN026 7157823 YP_002411949.1 CDS rutR NC_011751.1 1247139 1247777 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type r : regulator; DNA-binding transcriptional regulator 1247139..1247777 Escherichia coli UMN026 7157822 YP_002411950.1 CDS putA NC_011751.1 1247817 1251779 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1247817..1251779) Escherichia coli UMN026 7157829 YP_002411951.1 CDS putP NC_011751.1 1252202 1253710 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12923181, 88213396, 91227628, 93132799, 98359785, 1400239, 1567896, 3053649, 3053687, 3302614, 3325781, 8119910; Product type t : transporter; proline:sodium symporter 1252202..1253710 Escherichia coli UMN026 7157586 YP_002411952.1 CDS ECUMN_1199 NC_011751.1 1253858 1255201 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1253858..1255201) Escherichia coli UMN026 7157587 YP_002411953.1 CDS ECUMN_1200 NC_011751.1 1256210 1256356 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1256210..1256356) Escherichia coli UMN026 7154857 YP_002411954.1 CDS efeU NC_011751.1 1256383 1257222 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ferrous iron permease 1256383..1257222 Escherichia coli UMN026 7154858 YP_002411955.1 CDS efeO NC_011751.1 1257280 1258407 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 10493123; Product type t : transporter; hypothetical protein 1257280..1258407 Escherichia coli UMN026 7156230 YP_002411956.1 CDS efeB NC_011751.1 1258413 1259684 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 16551627, 15375152; Product type t : transporter; iron transport heme-binding periplasmic protein 1258413..1259684 Escherichia coli UMN026 7156229 YP_002411957.1 CDS ECUMN_1204 NC_011751.1 1259799 1259954 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1259799..1259954) Escherichia coli UMN026 7156228 YP_002411958.1 CDS phoH NC_011751.1 1260034 1261098 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8444794, 2160940; Product type pe : putative enzyme; hypothetical protein 1260034..1261098 Escherichia coli UMN026 7154859 YP_002411959.1 CDS ECUMN_1206 NC_011751.1 1261685 1262371 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1261685..1262371 Escherichia coli UMN026 7157458 YP_002411960.1 CDS ycdW NC_011751.1 1262786 1263724 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11237876, 10493123; Product type e : enzyme; 2-ketoacid reductase 1262786..1263724 Escherichia coli UMN026 7155641 YP_002411961.1 CDS ycdX NC_011751.1 1263779 1264516 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12661000; Product type pe : putative enzyme; putative hydrolase 1263779..1264516 Escherichia coli UMN026 7158520 YP_002411962.1 CDS ycdY NC_011751.1 1264540 1265094 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1264540..1265094 Escherichia coli UMN026 7158521 YP_002411963.1 CDS ycdZ NC_011751.1 1265196 1265687 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1265196..1265687 Escherichia coli UMN026 7158522 YP_002411964.1 CDS csgG NC_011751.1 1265751 1266584 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817489; Product type lp : lipoprotein; putative outer membrane lipoprotein involved in curli production assembly/transport complement(1265751..1266584) Escherichia coli UMN026 7158523 YP_002411965.1 CDS csgF NC_011751.1 1266611 1267027 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1266611..1267027) Escherichia coli UMN026 7156031 YP_002411966.1 CDS csgE NC_011751.1 1267052 1267441 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1267052..1267441) Escherichia coli UMN026 7156030 YP_002411967.1 CDS csgD NC_011751.1 1267446 1268096 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1267446..1268096) Escherichia coli UMN026 7156029 YP_002411968.1 CDS csgB NC_011751.1 1268851 1269306 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1268851..1269306 Escherichia coli UMN026 7156028 YP_002411969.1 CDS csgA NC_011751.1 1269347 1269802 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89201357, 93023873, 1677357, 8459772, 8817489, 1357528; Product type s : structure; cryptic curlin major subunit 1269347..1269802 Escherichia coli UMN026 7156026 YP_002411970.1 CDS csgC NC_011751.1 1269702 1270193 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein 1269702..1270193 Escherichia coli UMN026 7156025 YP_002411971.1 CDS ymdA NC_011751.1 1270314 1270625 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1270314..1270625 Escherichia coli UMN026 7156027 YP_002411972.1 CDS ymdB NC_011751.1 1270720 1271253 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1270720..1271253 Escherichia coli UMN026 7159474 YP_002411973.1 CDS ymdC NC_011751.1 1271255 1272676 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 1271255..1272676 Escherichia coli UMN026 7159475 YP_002411974.1 CDS mdoC NC_011751.1 1272684 1273841 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1272684..1273841) Escherichia coli UMN026 7159476 YP_002411975.1 CDS ECUMN_1222 NC_011751.1 1273886 1274029 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1273886..1274029) Escherichia coli UMN026 7157073 YP_002411976.1 CDS ECUMN_1223 NC_011751.1 1274033 1274191 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1274033..1274191) Escherichia coli UMN026 7154861 YP_002411977.1 CDS mdoG NC_011751.1 1274235 1275770 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1274235..1275770 Escherichia coli UMN026 7154862 YP_002411978.1 CDS mdoH NC_011751.1 1275763 1278306 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1275763..1278306 Escherichia coli UMN026 7157075 YP_002411979.1 CDS yceK NC_011751.1 1278479 1278706 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 1278479..1278706 Escherichia coli UMN026 7157076 YP_002411980.1 CDS msyB NC_011751.1 1278707 1279081 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165719; hypothetical protein complement(1278707..1279081) Escherichia coli UMN026 7158532 YP_002411981.1 CDS mdtG NC_011751.1 1279164 1280390 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1279164..1280390) Escherichia coli UMN026 7157189 YP_002411982.1 CDS lpxL NC_011751.1 1280562 1281482 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1280562..1281482) Escherichia coli UMN026 7157083 YP_002411983.1 CDS yceA NC_011751.1 1281707 1282759 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1840644; hypothetical protein 1281707..1282759 Escherichia coli UMN026 7157015 YP_002411984.1 CDS yceI NC_011751.1 1282801 1283376 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15741337, 11298273, 1840644, 9298646; Product type c : carrier; hypothetical protein complement(1282801..1283376) Escherichia coli UMN026 7158524 YP_002411985.1 CDS yceJ NC_011751.1 1283380 1283946 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome b561 complement(1283380..1283946) Escherichia coli UMN026 7158530 YP_002411986.1 CDS solA NC_011751.1 1284368 1285486 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1284368..1285486) Escherichia coli UMN026 7158531 YP_002411987.1 CDS bssS NC_011751.1 1285601 1285855 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1285601..1285855) Escherichia coli UMN026 7157952 YP_002411988.1 CDS dinI NC_011751.1 1286145 1286390 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9606202, 11152126, 11230150, 8682790; Product type f : factor; DNA damage-inducible protein I complement(1286145..1286390) Escherichia coli UMN026 7155893 YP_002411989.1 CDS pyrC NC_011751.1 1286464 1287510 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1286464..1287510) Escherichia coli UMN026 7156170 YP_002411990.1 CDS yceB NC_011751.1 1287616 1288176 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein complement(1287616..1288176) Escherichia coli UMN026 7157598 YP_002411991.1 CDS grxB NC_011751.1 1288310 1288957 R cofactor involved in the reduction of disulfides; glutaredoxin 2 complement(1288310..1288957) Escherichia coli UMN026 7158525 YP_002411992.1 CDS mdtH NC_011751.1 1289021 1290229 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1289021..1290229) Escherichia coli UMN026 7156615 YP_002411993.1 CDS rimJ NC_011751.1 1290465 1291049 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88121676, 90136529, 1356970; Product type e : enzyme; ribosomal-protein-S5-alanine N-acetyltransferase 1290465..1291049 Escherichia coli UMN026 7157084 YP_002411994.1 CDS yceH NC_011751.1 1291060 1291707 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1356970, 2828880; hypothetical protein 1291060..1291707 Escherichia coli UMN026 7157692 YP_002411995.1 CDS mviM NC_011751.1 1291709 1292632 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 1291709..1292632 Escherichia coli UMN026 7158529 YP_002411996.1 CDS mviN NC_011751.1 1292742 1294277 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1292742..1294277 Escherichia coli UMN026 7157217 YP_002411997.1 CDS flgN NC_011751.1 1294317 1294733 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10320579; Product type f : factor; export chaperone for FlgK and FlgL complement(1294317..1294733) Escherichia coli UMN026 7157218 YP_002411998.1 CDS flgM NC_011751.1 1294738 1295031 R regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM complement(1294738..1295031) Escherichia coli UMN026 7156390 YP_002411999.1 CDS flgA NC_011751.1 1295107 1295766 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1295107..1295766) Escherichia coli UMN026 7156389 YP_002412000.1 CDS flgB NC_011751.1 1295921 1296337 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1295921..1296337 Escherichia coli UMN026 7156377 YP_002412001.1 CDS flgC NC_011751.1 1296341 1296745 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1296341..1296745 Escherichia coli UMN026 7156378 YP_002412002.1 CDS flgD NC_011751.1 1296757 1297452 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1296757..1297452 Escherichia coli UMN026 7156379 YP_002412003.1 CDS flgE NC_011751.1 1297477 1298682 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1297477..1298682 Escherichia coli UMN026 7156380 YP_002412004.1 CDS flgF NC_011751.1 1298702 1299457 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1298702..1299457 Escherichia coli UMN026 7156381 YP_002412005.1 CDS flgG NC_011751.1 1299594 1300376 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1299594..1300376 Escherichia coli UMN026 7156382 YP_002412006.1 CDS flgH NC_011751.1 1300429 1301127 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1300429..1301127 Escherichia coli UMN026 7156383 YP_002412007.1 CDS flgI NC_011751.1 1301139 1302236 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1301139..1302236 Escherichia coli UMN026 7156384 YP_002412008.1 CDS flgJ NC_011751.1 1302236 1303177 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1302236..1303177 Escherichia coli UMN026 7156385 YP_002412009.1 CDS flgK NC_011751.1 1303243 1304886 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1303243..1304886 Escherichia coli UMN026 7156386 YP_002412010.1 CDS flgL NC_011751.1 1304898 1305851 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1304898..1305851 Escherichia coli UMN026 7156387 YP_002412011.1 CDS ECUMN_1258 NC_011751.1 1305946 1306455 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1305946..1306455) Escherichia coli UMN026 7156388 YP_002412012.1 CDS ECUMN_1259 NC_011751.1 1306437 1306775 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1306437..1306775) Escherichia coli UMN026 7154863 YP_002412013.1 CDS rne NC_011751.1 1306863 1310048 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1306863..1310048) Escherichia coli UMN026 7154864 YP_002412014.1 CDS rluC NC_011751.1 1310621 1311580 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1310621..1311580 Escherichia coli UMN026 7157711 YP_002412015.1 CDS yceF NC_011751.1 1311692 1312276 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1311692..1312276) Escherichia coli UMN026 7157701 YP_002412016.1 CDS yceD NC_011751.1 1312475 1312996 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 90008815, 1447160; hypothetical protein 1312475..1312996 Escherichia coli UMN026 7157970 YP_002412017.1 CDS rpmF NC_011751.1 1313048 1313221 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1313048..1313221 Escherichia coli UMN026 7158526 YP_002412018.1 CDS plsX NC_011751.1 1313302 1314372 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1313302..1314372 Escherichia coli UMN026 7157753 YP_002412019.1 CDS fabH NC_011751.1 1314440 1315393 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 1314440..1315393 Escherichia coli UMN026 7157474 YP_002412020.1 CDS fabD NC_011751.1 1315409 1316338 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052166, 92183950, 92210530, 92234941, 7700236, 7768883, 9298646; Product type e : enzyme; malonyl-CoA-[acyl-carrier-protein] transacylase 1315409..1316338 Escherichia coli UMN026 7156298 YP_002412021.1 CDS fabG NC_011751.1 1316351 1317085 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 1316351..1317085 Escherichia coli UMN026 7156295 YP_002412022.1 CDS acpP NC_011751.1 1317296 1317532 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1317296..1317532 Escherichia coli UMN026 7156297 YP_002412023.1 CDS fabF NC_011751.1 1317620 1318861 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1317620..1318861 Escherichia coli UMN026 7155684 YP_002412024.1 CDS ECUMN_1271 NC_011751.1 1318910 1319098 D Evidence 6 : Doubtful CDS; hypothetical protein 1318910..1319098 Escherichia coli UMN026 7156296 YP_002412025.1 CDS ECUMN_1272 NC_011751.1 1319004 1319513 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group 1319004..1319513 Escherichia coli UMN026 7154865 YP_002412026.1 CDS pabC NC_011751.1 1319693 1320502 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1319693..1320502 Escherichia coli UMN026 7154866 YP_002412027.1 CDS yceG NC_011751.1 1320505 1321527 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 1320505..1321527 Escherichia coli UMN026 7157375 YP_002412028.1 CDS tmk NC_011751.1 1321517 1322158 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1321517..1322158 Escherichia coli UMN026 7158528 YP_002412029.1 CDS holB NC_011751.1 1322155 1323159 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1322155..1323159 Escherichia coli UMN026 7158077 YP_002412030.1 CDS ycfH NC_011751.1 1323170 1323967 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8505303, 8509334, 10747959; Product type pe : putative enzyme; putative metallodependent hydrolase 1323170..1323967 Escherichia coli UMN026 7156697 YP_002412031.1 CDS ptsG NC_011751.1 1324262 1325695 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1324262..1325695 Escherichia coli UMN026 7158534 YP_002412032.1 CDS fhuE NC_011751.1 1325755 1327944 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90286919, 3032906, 10529396; Product type t : transporter; ferric-rhodotorulic acid outer membrane transporter complement(1325755..1327944) Escherichia coli UMN026 7157566 YP_002412033.1 CDS hinT NC_011751.1 1328278 1328637 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15703176, 10493123, 2162465; Product type e : enzyme; purine nucleoside phosphoramidase 1328278..1328637 Escherichia coli UMN026 7156348 YP_002412034.1 CDS ycfL NC_011751.1 1328640 1329017 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1328640..1329017 Escherichia coli UMN026 7156670 YP_002412035.1 CDS ycfM NC_011751.1 1329031 1329672 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane lipoprotein 1329031..1329672 Escherichia coli UMN026 7158536 YP_002412036.1 CDS thiK NC_011751.1 1329653 1330477 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1329653..1330477 Escherichia coli UMN026 7158537 YP_002412037.1 CDS nagZ NC_011751.1 1330488 1331513 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1330488..1331513 Escherichia coli UMN026 7158538 YP_002412038.1 CDS ycfP NC_011751.1 1331536 1332078 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1331536..1332078 Escherichia coli UMN026 7157232 YP_002412039.1 CDS ndh NC_011751.1 1332478 1333782 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766919, 20130027, 81256452, 92296775, 94042945, 99441207, 6265208; Product type e : enzyme; respiratory NADH dehydrogenase 2/cupric reductase 1332478..1333782 Escherichia coli UMN026 7158539 YP_002412040.1 CDS ycfJ NC_011751.1 1334009 1334548 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6265208, 7984428; hypothetical protein 1334009..1334548 Escherichia coli UMN026 7157261 YP_002412041.1 CDS ycfQ NC_011751.1 1334610 1335242 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(1334610..1335242) Escherichia coli UMN026 7158535 YP_002412042.1 CDS ycfR NC_011751.1 1335483 1335740 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089; hypothetical protein 1335483..1335740 Escherichia coli UMN026 7158540 YP_002412043.1 CDS ycfS NC_011751.1 1335823 1336785 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1335823..1336785) Escherichia coli UMN026 7158541 YP_002412044.1 CDS mfd NC_011751.1 1336930 1340376 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14602898, 90158497, 92107993, 8465200; Product type f : factor; transcription-repair coupling factor complement(1336930..1340376) Escherichia coli UMN026 7158542 YP_002412045.1 CDS ycfT NC_011751.1 1340504 1341577 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1340504..1341577) Escherichia coli UMN026 7157114 YP_002412046.1 CDS lolC NC_011751.1 1341838 1343037 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1341838..1343037 Escherichia coli UMN026 7158543 YP_002412047.1 CDS lolD NC_011751.1 1343030 1343731 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1343030..1343731 Escherichia coli UMN026 7156996 YP_002412048.1 CDS lolE NC_011751.1 1343731 1344975 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1343731..1344975 Escherichia coli UMN026 7156997 YP_002412049.1 CDS ycfX NC_011751.1 1345004 1345915 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1345004..1345915 Escherichia coli UMN026 7156998 YP_002412050.1 CDS cobB NC_011751.1 1345931 1346752 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1345931..1346752 Escherichia coli UMN026 7158544 YP_002412051.1 CDS ycfZ NC_011751.1 1346890 1347675 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1346890..1347675) Escherichia coli UMN026 7155991 YP_002412052.1 CDS ymfA NC_011751.1 1347672 1348133 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1347672..1348133) Escherichia coli UMN026 7158545 YP_002412053.1 CDS potD NC_011751.1 1348191 1349237 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter periplasmic substrate-binding protein complement(1348191..1349237) Escherichia coli UMN026 7159478 YP_002412054.1 CDS potC NC_011751.1 1349234 1350028 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1349234..1350028) Escherichia coli UMN026 7157490 YP_002412055.1 CDS int NC_011751.1 1350195 1351313 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Integrase from bacteriophage origin complement(1350195..1351313) Escherichia coli UMN026 7157489 YP_002412056.1 CDS ECUMN_1304 NC_011751.1 1351282 1351560 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative excisionase for bacteriophage origin complement(1351282..1351560) Escherichia coli UMN026 7156840 YP_002412057.1 CDS ECUMN_1305 NC_011751.1 1351613 1354069 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2199308; Product type h : extrachromosomal origin; Exodeoxyribonuclease VIII from bacteriophage origin complement(1351613..1354069) Escherichia coli UMN026 7154867 YP_002412058.1 CDS ECUMN_1306 NC_011751.1 1354147 1354350 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1354147..1354350) Escherichia coli UMN026 7154868 YP_002412059.1 CDS dicB NC_011751.1 1354347 1354535 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3041373; Product type h : extrachromosomal origin; Cell division inhibition protein dicB from bacteriophage origin complement(1354347..1354535) Escherichia coli UMN026 7154869 YP_002412060.1 CDS ECUMN_1308 NC_011751.1 1354546 1355400 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1354546..1355400) Escherichia coli UMN026 7156163 YP_002412061.1 CDS ECUMN_1309 NC_011751.1 1355931 1356317 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(1355931..1356317) Escherichia coli UMN026 7154870 YP_002412062.1 CDS dicA NC_011751.1 1356676 1357083 R The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA complement(1356676..1357083) Escherichia coli UMN026 7158644 YP_002412063.1 CDS dicC NC_011751.1 1357160 1357387 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88232418, 3532030; Product type h : extrachromosomal origin; DNA-binding transcriptional regulator DicC 1357160..1357387 Escherichia coli UMN026 7156161 YP_002412064.1 CDS ECUMN_1313 NC_011751.1 1357371 1357922 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1357371..1357922 Escherichia coli UMN026 7156164 YP_002412065.1 CDS ECUMN_1314 NC_011751.1 1357819 1358934 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1357819..1358934 Escherichia coli UMN026 7154872 YP_002412066.1 CDS ECUMN_1315 NC_011751.1 1358927 1359388 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1358927..1359388 Escherichia coli UMN026 7154873 YP_002412067.1 CDS ECUMN_1316 NC_011751.1 1359404 1360192 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1359404..1360192 Escherichia coli UMN026 7154874 YP_002412068.1 CDS ECUMN_1317 NC_011751.1 1360193 1360600 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1360193..1360600 Escherichia coli UMN026 7154875 YP_002412069.1 CDS ECUMN_1318 NC_011751.1 1360597 1360893 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1360597..1360893 Escherichia coli UMN026 7154876 YP_002412070.1 CDS ECUMN_1319 NC_011751.1 1360890 1361351 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1360890..1361351 Escherichia coli UMN026 7154877 YP_002412071.1 CDS ECUMN_1320 NC_011751.1 1361329 1361685 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1361329..1361685 Escherichia coli UMN026 7154878 YP_002412072.1 CDS ECUMN_1321 NC_011751.1 1361781 1362188 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1361781..1362188 Escherichia coli UMN026 7154879 YP_002412073.1 CDS ECUMN_1322 NC_011751.1 1362190 1362555 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative HNH endonuclease from bacteriophage origin 1362190..1362555 Escherichia coli UMN026 7154880 YP_002412074.1 CDS ECUMN_1323 NC_011751.1 1362552 1363538 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1362552..1363538 Escherichia coli UMN026 7154881 YP_002412075.1 CDS rem NC_011751.1 1364469 1364720 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2990907; Product type h : extrachromosomal origin; hypothetical protein 1364469..1364720 Escherichia coli UMN026 7154882 YP_002412076.1 CDS ECUMN_1325 NC_011751.1 1364787 1365065 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1364787..1365065 Escherichia coli UMN026 7157650 YP_002412077.1 CDS ydfU NC_011751.1 1365067 1366125 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1365067..1366125 Escherichia coli UMN026 7154883 YP_002412078.1 CDS ECUMN_1327 NC_011751.1 1366126 1366494 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative crossover junction endodeoxyribonuclease rusA 1366126..1366494 Escherichia coli UMN026 7158656 YP_002412079.1 CDS Q NC_011751.1 1366481 1367176 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Antitermination protein Q 1366481..1367176 Escherichia coli UMN026 7154884 YP_002412080.1 CDS ECUMN_1329 NC_011751.1 1367254 1367586 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1367254..1367586 Escherichia coli UMN026 7157608 YP_002412081.1 CDS ECUMN_1330 NC_011751.1 1367528 1367824 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1367528..1367824 Escherichia coli UMN026 7154885 YP_002412082.1 CDS ECUMN_1332 NC_011751.1 1368737 1368898 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1368737..1368898 Escherichia coli UMN026 7154887 YP_002412083.1 CDS essD NC_011751.1 1369048 1369263 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative phage lysis protein S; DLP12 prophage 1369048..1369263 Escherichia coli UMN026 7154888 YP_002412084.1 CDS ECUMN_1334 NC_011751.1 1369265 1370158 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1369265..1370158 Escherichia coli UMN026 7156270 YP_002412085.1 CDS ydfQ NC_011751.1 1370195 1370728 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated lysozyme; Qin prophage 1370195..1370728 Escherichia coli UMN026 7154889 YP_002412086.1 CDS ECUMN_1336 NC_011751.1 1370852 1371067 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1370852..1371067 Escherichia coli UMN026 7158652 YP_002412087.1 CDS rz NC_011751.1 1371210 1371683 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Endopeptidase from bacteriophage origin 1371210..1371683 Escherichia coli UMN026 7154890 YP_002412088.1 CDS ECUMN_1338 NC_011751.1 1371940 1372320 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tonB-like membrane protein encoded within prophage 1371940..1372320 Escherichia coli UMN026 7157861 YP_002412089.1 CDS ECUMN_1339 NC_011751.1 1372443 1372796 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1372443..1372796) Escherichia coli UMN026 7154891 YP_002412090.1 CDS ECUMN_1341 NC_011751.1 1372684 1373004 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1372684..1373004) Escherichia coli UMN026 7154893 YP_002412091.1 CDS ECUMN_1342 NC_011751.1 1373279 1373788 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Terminase small subunit (DNA packaging protein Nu1) from bacteriophage origin 1373279..1373788 Escherichia coli UMN026 7154894 YP_002412092.1 CDS ECUMN_1343 NC_011751.1 1373790 1375688 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Terminase large subunit (Gp2) 1373790..1375688 Escherichia coli UMN026 7154895 YP_002412093.1 CDS ECUMN_1344 NC_011751.1 1375672 1375878 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Head stabilization protein (Head protein GP3) 1375672..1375878 Escherichia coli UMN026 7154896 YP_002412094.1 CDS ECUMN_1345 NC_011751.1 1375875 1377467 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; portal protein (Head protein GP4) 1375875..1377467 Escherichia coli UMN026 7154897 YP_002412095.1 CDS ECUMN_1346 NC_011751.1 1377457 1378905 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Head-tail preconnector protein GP5 1377457..1378905 Escherichia coli UMN026 7154898 YP_002412096.1 CDS ECUMN_1347 NC_011751.1 1378942 1379289 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Head decoration protein (Head protein GPshp) 1378942..1379289 Escherichia coli UMN026 7154899 YP_002412097.1 CDS ECUMN_1348 NC_011751.1 1379347 1380375 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major head protein (Head protein gp7) 1379347..1380375 Escherichia coli UMN026 7154900 YP_002412098.1 CDS ECUMN_1349 NC_011751.1 1380379 1380801 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1380379..1380801 Escherichia coli UMN026 7154901 YP_002412099.1 CDS ECUMN_1350 NC_011751.1 1380794 1381147 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail attachment protein (Minor capsid protein FII) 1380794..1381147 Escherichia coli UMN026 7154902 YP_002412100.1 CDS ECUMN_1351 NC_011751.1 1381163 1381696 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GpZ) 1381163..1381696 Escherichia coli UMN026 7154903 YP_002412101.1 CDS ECUMN_1352 NC_011751.1 1381693 1382088 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 1381693..1382088 Escherichia coli UMN026 7154904 YP_002412102.1 CDS ECUMN_1353 NC_011751.1 1382096 1382845 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 1382096..1382845 Escherichia coli UMN026 7154905 YP_002412103.1 CDS ECUMN_1354 NC_011751.1 1382864 1383295 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein G 1382864..1383295 Escherichia coli UMN026 7154906 YP_002412104.1 CDS ECUMN_1355 NC_011751.1 1383322 1383735 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein T 1383322..1383735 Escherichia coli UMN026 7154907 YP_002412105.1 CDS ECUMN_1356 NC_011751.1 1383716 1386277 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein H 1383716..1386277 Escherichia coli UMN026 7154908 YP_002412106.1 CDS ECUMN_1357 NC_011751.1 1386274 1386603 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 1386274..1386603 Escherichia coli UMN026 7154909 YP_002412107.1 CDS ECUMN_1358 NC_011751.1 1386501 1386617 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1386501..1386617) Escherichia coli UMN026 7154910 YP_002412108.1 CDS ECUMN_1359 NC_011751.1 1386603 1387301 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 1386603..1387301 Escherichia coli UMN026 7154911 YP_002412109.1 CDS ECUMN_1360 NC_011751.1 1387312 1388055 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail fiber component K 1387312..1388055 Escherichia coli UMN026 7154912 YP_002412110.1 CDS ECUMN_1361 NC_011751.1 1387953 1388633 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I 1387953..1388633 Escherichia coli UMN026 7154913 YP_002412111.1 CDS ECUMN_1362 NC_011751.1 1388977 1392669 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J 1388977..1392669 Escherichia coli UMN026 7154914 YP_002412112.1 CDS ECUMN_1363 NC_011751.1 1392737 1393336 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Lom-like outer membrane protein of phage origin 1392737..1393336 Escherichia coli UMN026 7154915 YP_002412113.1 CDS ECUMN_1364 NC_011751.1 1393488 1396514 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Side tail fiber protein from bacteriophage origin 1393488..1396514 Escherichia coli UMN026 7154916 YP_002412114.1 CDS tfaQ NC_011751.1 1396514 1397098 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative tail fiber chaperone; Qin prophage 1396514..1397098 Escherichia coli UMN026 7154917 YP_002412115.1 CDS ybcY NC_011751.1 1397153 1397737 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AdoMet-dependent methyltransferase; DLP12 prophage complement(1397153..1397737) Escherichia coli UMN026 7158049 YP_002412116.1 CDS ECUMN_1367 NC_011751.1 1397878 1398144 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber assembly protein 1397878..1398144 Escherichia coli UMN026 7158389 YP_002412117.1 CDS potB NC_011751.1 1398376 1399239 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1398376..1399239) Escherichia coli UMN026 7154918 YP_002412118.1 CDS potA NC_011751.1 1399223 1400359 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein complement(1399223..1400359) Escherichia coli UMN026 7157488 YP_002412119.1 CDS ECUMN_1370 NC_011751.1 1400338 1400589 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1400338..1400589) Escherichia coli UMN026 7157487 YP_002412120.1 CDS pepT NC_011751.1 1400609 1401835 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1400609..1401835 Escherichia coli UMN026 7154919 YP_002412121.1 CDS ycfD NC_011751.1 1401884 1403005 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1401884..1403005) Escherichia coli UMN026 7157417 YP_002412122.1 CDS phoQ NC_011751.1 1403081 1404541 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105017; Product type r : regulator; sensor protein PhoQ complement(1403081..1404541) Escherichia coli UMN026 7158533 YP_002412123.1 CDS phoP NC_011751.1 1404541 1405212 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1404541..1405212) Escherichia coli UMN026 7157460 YP_002412124.1 CDS purB NC_011751.1 1405381 1406751 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1405381..1406751) Escherichia coli UMN026 7157459 YP_002412125.1 CDS hflD NC_011751.1 1406755 1407396 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1406755..1407396) Escherichia coli UMN026 7157573 YP_002412126.1 CDS mnmA NC_011751.1 1407432 1408538 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA -specific 2-thiouridylase MnmA complement(1407432..1408538) Escherichia coli UMN026 7156664 YP_002412127.1 CDS ymfB NC_011751.1 1408592 1409053 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; bifunctional thiamin pyrimidine pyrophosphate hydrolase and thiamin pyrophosphate hydrolase complement(1408592..1409053) Escherichia coli UMN026 7158116 YP_002412128.1 CDS ymfC NC_011751.1 1409063 1409716 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1409063..1409716) Escherichia coli UMN026 7159479 YP_002412129.1 CDS icd NC_011751.1 1409888 1411138 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1409888..1411138 Escherichia coli UMN026 7159480 YP_002412130.1 CDS int NC_011751.1 1411252 1412394 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage integrase complement(1411252..1412394) Escherichia coli UMN026 7156784 YP_002412131.1 CDS ymfG NC_011751.1 1412384 1412620 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative excisionase complement(1412384..1412620) Escherichia coli UMN026 7156841 YP_002412132.1 CDS ECUMN_1383 NC_011751.1 1412760 1412999 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1412760..1412999) Escherichia coli UMN026 7159481 YP_002412133.1 CDS ECUMN_1384 NC_011751.1 1413047 1413265 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1413047..1413265) Escherichia coli UMN026 7154920 YP_002412134.1 CDS ECUMN_1385 NC_011751.1 1413364 1413663 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1413364..1413663) Escherichia coli UMN026 7154921 YP_002412135.1 CDS ECUMN_1386 NC_011751.1 1413656 1413847 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1413656..1413847) Escherichia coli UMN026 7154922 YP_002412136.1 CDS ECUMN_1387 NC_011751.1 1413999 1414679 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; exonuclease from phage origin complement(1413999..1414679) Escherichia coli UMN026 7154923 YP_002412137.1 CDS ECUMN_1388 NC_011751.1 1414676 1415461 R Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin; recombination protein bet from phage origin complement(1414676..1415461) Escherichia coli UMN026 7154924 YP_002412138.1 CDS gam NC_011751.1 1415467 1415883 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Host-nuclease inhibitor protein gam from bacteriophage origin complement(1415467..1415883) Escherichia coli UMN026 7154925 YP_002412139.1 CDS kil NC_011751.1 1415838 1416107 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host killing protein from bacteriophage origin complement(1415838..1416107) Escherichia coli UMN026 7156502 YP_002412140.1 CDS ECUMN_1391 NC_011751.1 1416187 1416555 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative single-stranded DNA binding protein of prophage complement(1416187..1416555) Escherichia coli UMN026 7156908 YP_002412141.1 CDS ECUMN_1392 NC_011751.1 1416816 1417397 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8335629; Product type h : extrachromosomal origin; Superinfection exclusion protein B 1416816..1417397 Escherichia coli UMN026 7154926 YP_002412142.1 CDS ECUMN_1393 NC_011751.1 1417414 1417806 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative regulatory protein N complement(1417414..1417806) Escherichia coli UMN026 7154927 YP_002412143.1 CDS ECUMN_1394 NC_011751.1 1417808 1417981 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(1417808..1417981) Escherichia coli UMN026 7154928 YP_002412144.1 CDS ECUMN_1395 NC_011751.1 1418165 1419064 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1418165..1419064) Escherichia coli UMN026 7154929 YP_002412145.1 CDS cI NC_011751.1 1419194 1419901 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; repressor protein of bacteriophage origin complement(1419194..1419901) Escherichia coli UMN026 7154930 YP_002412146.1 CDS cro NC_011751.1 1419980 1420207 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; regulatory protein from bacteriophage origin 1419980..1420207 Escherichia coli UMN026 7155963 YP_002412147.1 CDS ECUMN_1398 NC_011751.1 1420314 1420613 D Evidence 2b : Function of strongly homologous gene; PubMedId : 375198; Product type h : extrachromosomal origin; regulatory protein CII from phage origin 1420314..1420613 Escherichia coli UMN026 7156016 YP_002412148.1 CDS O NC_011751.1 1420646 1421545 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; replication protein from bacteriophage origin 1420646..1421545 Escherichia coli UMN026 7157355 YP_002412149.1 CDS ECUMN_1400 NC_011751.1 1421542 1422243 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative replication protein P of bacteriophage 1421542..1422243 Escherichia coli UMN026 7157341 YP_002412150.1 CDS ECUMN_1401 NC_011751.1 1422240 1422530 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; ren protein from phage origin 1422240..1422530 Escherichia coli UMN026 7154932 YP_002412151.1 CDS ECUMN_1402 NC_011751.1 1422586 1423044 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; recombination protein ninB from phage origin 1422586..1423044 Escherichia coli UMN026 7154933 YP_002412152.1 CDS ECUMN_1403 NC_011751.1 1422981 1423568 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative DNA N-6-adenine-methyltransferase from phage origin 1422981..1423568 Escherichia coli UMN026 7154934 YP_002412153.1 CDS ECUMN_1404 NC_011751.1 1423702 1424085 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1423702..1424085 Escherichia coli UMN026 7154935 YP_002412154.1 CDS rusA NC_011751.1 1424292 1424654 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1424292..1424654 Escherichia coli UMN026 7154936 YP_002412155.1 CDS ybcQ NC_011751.1 1424862 1425254 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8648624, 9278503; Product type pf : putative factor; putative antitermination protein Q-like protein; DLP12 prophage 1424862..1425254 Escherichia coli UMN026 7157821 YP_002412156.1 CDS blc NC_011751.1 1425411 1425935 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(1425411..1425935) Escherichia coli UMN026 7158384 YP_002412157.1 CDS ECUMN_1408 NC_011751.1 1426128 1427087 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1426128..1427087 Escherichia coli UMN026 7155886 YP_002412158.1 CDS ECUMN_1409 NC_011751.1 1427397 1428137 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative araC-type regulatory protein from bacteriophage origin 1427397..1428137 Escherichia coli UMN026 7154937 YP_002412159.1 CDS essD NC_011751.1 1428305 1428520 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative phage lysis protein S; DLP12 prophage 1428305..1428520 Escherichia coli UMN026 7154938 YP_002412160.1 CDS ybcS NC_011751.1 1428520 1429017 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : putative enzyme; putative lysozyme; DLP12 prophage 1428520..1429017 Escherichia coli UMN026 7156271 YP_002412161.1 CDS rzpD NC_011751.1 1429014 1429475 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative murein endopeptidase; DLP12 prophage 1429014..1429475 Escherichia coli UMN026 7158386 YP_002412162.1 CDS borD NC_011751.1 1429507 1429800 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 95173101; Product type pm : putative membrane component; putative lipoprotein; DLP12 prophage complement(1429507..1429800) Escherichia coli UMN026 7157862 YP_002412163.1 CDS ynfO NC_011751.1 1430160 1430354 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1430160..1430354) Escherichia coli UMN026 7155890 YP_002412164.1 CDS nohB NC_011751.1 1430743 1431288 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92334985; Product type h : extrachromosomal origin; DNA packaging protein; DLP12 prophage 1430743..1431288 Escherichia coli UMN026 7159529 YP_002412165.1 CDS A NC_011751.1 1431263 1433188 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Terminase large subunit from bacteriophage origin 1431263..1433188 Escherichia coli UMN026 7157293 YP_002412166.1 CDS W NC_011751.1 1433185 1433391 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11302702; Product type h : extrachromosomal origin; Head-to-tail joining protein W (gpW) from bacteriophage origin 1433185..1433391 Escherichia coli UMN026 7155654 YP_002412167.1 CDS B NC_011751.1 1433388 1434989 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; portal protein; minor capsid protein 1433388..1434989 Escherichia coli UMN026 7158214 YP_002412168.1 CDS C NC_011751.1 1434970 1436289 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Minor capsid protein 1434970..1436289 Escherichia coli UMN026 7155847 YP_002412169.1 CDS D NC_011751.1 1436293 1436631 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Head decoration protein from bacteriophage origin 1436293..1436631 Escherichia coli UMN026 7155901 YP_002412170.1 CDS E NC_011751.1 1436660 1437712 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Major head coat protein from bacteriophage origin 1436660..1437712 Escherichia coli UMN026 7156098 YP_002412171.1 CDS fI NC_011751.1 1437715 1438149 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; DNA packaging protein from bacteriophage origin 1437715..1438149 Escherichia coli UMN026 7156217 YP_002412172.1 CDS fII NC_011751.1 1438161 1438514 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Tail attachment protein from bacteriophage origin 1438161..1438514 Escherichia coli UMN026 7156351 YP_002412173.1 CDS ECUMN_1424 NC_011751.1 1438526 1439104 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GpZ) 1438526..1439104 Escherichia coli UMN026 7156355 YP_002412174.1 CDS ECUMN_1425 NC_011751.1 1439101 1439496 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 1439101..1439496 Escherichia coli UMN026 7154939 YP_002412175.1 CDS ECUMN_1426 NC_011751.1 1439474 1440244 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 1439474..1440244 Escherichia coli UMN026 7154940 YP_002412176.1 CDS ECUMN_1427 NC_011751.1 1440260 1440682 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein G 1440260..1440682 Escherichia coli UMN026 7154941 YP_002412177.1 CDS ECUMN_1428 NC_011751.1 1440664 1441098 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein T 1440664..1441098 Escherichia coli UMN026 7154942 YP_002412178.1 CDS ECUMN_1429 NC_011751.1 1441091 1443670 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein H 1441091..1443670 Escherichia coli UMN026 7154943 YP_002412179.1 CDS ECUMN_1430 NC_011751.1 1443667 1443996 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 1443667..1443996 Escherichia coli UMN026 7154944 YP_002412180.1 CDS ECUMN_1431 NC_011751.1 1443996 1444694 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 1443996..1444694 Escherichia coli UMN026 7154945 YP_002412181.1 CDS ECUMN_1432 NC_011751.1 1444700 1445443 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber component K of prophage 1444700..1445443 Escherichia coli UMN026 7154946 YP_002412182.1 CDS ECUMN_1433 NC_011751.1 1445341 1446012 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I 1445341..1446012 Escherichia coli UMN026 7154947 YP_002412183.1 CDS ECUMN_1434 NC_011751.1 1446073 1449555 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J of prophage 1446073..1449555 Escherichia coli UMN026 7154948 YP_002412184.1 CDS ECUMN_1436 NC_011751.1 1451632 1451910 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1451632..1451910 Escherichia coli UMN026 7154950 YP_002412185.1 CDS ECUMN_1437 NC_011751.1 1451923 1452216 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1451923..1452216 Escherichia coli UMN026 7154951 YP_002412186.1 CDS sitD NC_011751.1 1452308 1453165 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component; iron transport protein, inner membrane component complement(1452308..1453165) Escherichia coli UMN026 7154952 YP_002412187.1 CDS sitC NC_011751.1 1453162 1454019 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component; iron transport protein, inner membrane component complement(1453162..1454019) Escherichia coli UMN026 7157932 YP_002412188.1 CDS sitB NC_011751.1 1454016 1454843 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component; iron transport protein, ATP-binding component complement(1454016..1454843) Escherichia coli UMN026 7157931 YP_002412189.1 CDS sitA NC_011751.1 1454843 1455757 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type t : transporter; iron transport protein, periplasmic-binding protein complement(1454843..1455757) Escherichia coli UMN026 7157930 YP_002412190.1 CDS ECUMN_1442 NC_011751.1 1456445 1457215 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1456445..1457215 Escherichia coli UMN026 7157929 YP_002412191.1 CDS ECUMN_1443 NC_011751.1 1457338 1457493 D Evidence 6 : Doubtful CDS; hypothetical protein 1457338..1457493 Escherichia coli UMN026 7154953 YP_002412192.1 CDS elbA NC_011751.1 1457942 1458265 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9603997; hypothetical protein complement(1457942..1458265) Escherichia coli UMN026 7156785 YP_002412193.1 CDS ycgX NC_011751.1 1458968 1459372 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1458968..1459372) Escherichia coli UMN026 7156238 YP_002412194.1 CDS ycgE NC_011751.1 1459593 1460324 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(1459593..1460324) Escherichia coli UMN026 7158557 YP_002412195.1 CDS ycgF NC_011751.1 1460529 1461740 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16533062, 15453820; Product type pe : putative enzyme; putative cyclic-di-GMP phosphodiesterase complement(1460529..1461740) Escherichia coli UMN026 7158547 YP_002412196.1 CDS ycgZ NC_011751.1 1462054 1462290 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1462054..1462290 Escherichia coli UMN026 7158548 YP_002412197.1 CDS ymgA NC_011751.1 1462333 1462605 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1462333..1462605 Escherichia coli UMN026 7158558 YP_002412198.1 CDS ymgB NC_011751.1 1462634 1462900 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1462634..1462900 Escherichia coli UMN026 7159486 YP_002412199.1 CDS ymgC NC_011751.1 1463013 1463261 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1463013..1463261 Escherichia coli UMN026 7159487 YP_002412200.1 CDS ECUMN_1453 NC_011751.1 1463564 1463737 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1463564..1463737) Escherichia coli UMN026 7159488 YP_002412201.1 CDS ymgF NC_011751.1 1465252 1465470 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1465252..1465470 Escherichia coli UMN026 7158549 YP_002412202.1 CDS ECUMN_1456 NC_011751.1 1465475 1465618 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1465475..1465618) Escherichia coli UMN026 7159491 YP_002412203.1 CDS ECUMN_1458 NC_011751.1 1465870 1466853 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1465870..1466853 Escherichia coli UMN026 7154956 YP_002412204.1 CDS ECUMN_1459 NC_011751.1 1466883 1468532 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1466883..1468532 Escherichia coli UMN026 7154957 YP_002412205.1 CDS ymgD NC_011751.1 1468588 1468917 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1468588..1468917) Escherichia coli UMN026 7154958 YP_002412206.1 CDS ymgG NC_011751.1 1468927 1469202 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1468927..1469202) Escherichia coli UMN026 7159489 YP_002412207.1 CDS ECUMN_1462 NC_011751.1 1469748 1470191 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1469748..1470191 Escherichia coli UMN026 7159492 YP_002412208.1 CDS minE NC_011751.1 1470556 1470822 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1470556..1470822) Escherichia coli UMN026 7154959 YP_002412209.1 CDS minD NC_011751.1 1470826 1471638 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1470826..1471638) Escherichia coli UMN026 7157135 YP_002412210.1 CDS minC NC_011751.1 1471662 1472357 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1471662..1472357) Escherichia coli UMN026 7157134 YP_002412211.1 CDS ycgJ NC_011751.1 1472877 1473245 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1472877..1473245 Escherichia coli UMN026 7157133 YP_002412212.1 CDS ycgK NC_011751.1 1473348 1473749 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1473348..1473749) Escherichia coli UMN026 7158550 YP_002412213.1 CDS ycgL NC_011751.1 1473957 1474283 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1473957..1474283 Escherichia coli UMN026 7158551 YP_002412214.1 CDS ycgM NC_011751.1 1474355 1475014 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15551868; Product type pe : putative enzyme; hypothetical protein 1474355..1475014 Escherichia coli UMN026 7158552 YP_002412215.1 CDS ycgN NC_011751.1 1475106 1475552 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1475106..1475552 Escherichia coli UMN026 7158553 YP_002412216.1 CDS hlyE NC_011751.1 1475759 1476670 R Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E complement(1475759..1476670) Escherichia coli UMN026 7158554 YP_002412217.1 CDS umuD NC_011751.1 1477042 1477461 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1477042..1477461 Escherichia coli UMN026 7156688 YP_002412218.1 CDS umuC NC_011751.1 1477461 1478729 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1477461..1478729 Escherichia coli UMN026 7158187 YP_002412219.1 CDS dsbB NC_011751.1 1478775 1479305 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1478775..1479305) Escherichia coli UMN026 7158186 YP_002412220.1 CDS nhaB NC_011751.1 1479451 1480992 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1479451..1480992) Escherichia coli UMN026 7156203 YP_002412221.1 CDS fadR NC_011751.1 1481214 1481933 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1481214..1481933 Escherichia coli UMN026 7157272 YP_002412222.1 CDS ycgB NC_011751.1 1481984 1483516 R Evidence 4 : Homologs of previously reported genes of unknown function; SpoVR family protein complement(1481984..1483516) Escherichia coli UMN026 7156308 YP_002412223.1 CDS dadA NC_011751.1 1483846 1485144 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1483846..1485144 Escherichia coli UMN026 7158546 YP_002412224.1 CDS dadX NC_011751.1 1485154 1486224 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1485154..1486224 Escherichia coli UMN026 7156103 YP_002412225.1 CDS ECUMN_1480 NC_011751.1 1486392 1487828 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1486392..1487828) Escherichia coli UMN026 7156104 YP_002412226.1 CDS ECUMN_1481 NC_011751.1 1488154 1488375 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1488154..1488375 Escherichia coli UMN026 7154960 YP_002412227.1 CDS cvrA NC_011751.1 1488477 1490213 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1488477..1490213) Escherichia coli UMN026 7154961 YP_002412228.1 CDS ldcA NC_011751.1 1490308 1491222 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1490308..1491222) Escherichia coli UMN026 7156059 YP_002412229.1 CDS emtA NC_011751.1 1491322 1491933 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98317285; Product type e : enzyme; lytic murein endotransglycosylase E 1491322..1491933 Escherichia coli UMN026 7156935 YP_002412230.1 CDS ycgR NC_011751.1 1491935 1492669 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11031114; Product type cp : cell process; protein involved in flagellar function complement(1491935..1492669) Escherichia coli UMN026 7156245 YP_002412231.1 CDS ymgE NC_011751.1 1492870 1493124 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative inner membrane protein with transglycosylase-associated domain 1492870..1493124 Escherichia coli UMN026 7158555 YP_002412232.1 CDS prrA NC_011751.1 1493174 1495165 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative outer membrane receptor complement(1493174..1495165) Escherichia coli UMN026 7159490 YP_002412233.1 CDS modD NC_011751.1 1495170 1496024 R involved in molybdenum transport; molybdenum transport protein ModD complement(1495170..1496024) Escherichia coli UMN026 7157545 YP_002412234.1 CDS ECUMN_1489 NC_011751.1 1496021 1496833 R Evidence 4 : Homologs of previously reported genes of unknown function; putative SAM-dependent methyltransferase complement(1496021..1496833) Escherichia coli UMN026 7157155 YP_002412235.1 CDS ECUMN_1490 NC_011751.1 1496843 1497739 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ABC transporter ATP-binding protein complement(1496843..1497739) Escherichia coli UMN026 7154962 YP_002412236.1 CDS ECUMN_1491 NC_011751.1 1497598 1498578 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative ABC transporter permease protein complement(1497598..1498578) Escherichia coli UMN026 7154963 YP_002412237.1 CDS ECUMN_1492 NC_011751.1 1498578 1499642 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter periplasmic binding protein complement(1498578..1499642) Escherichia coli UMN026 7154964 YP_002412238.1 CDS treA NC_011751.1 1499929 1501626 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1499929..1501626) Escherichia coli UMN026 7154965 YP_002412239.1 CDS dhaH NC_011751.1 1501945 1503363 R phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit M complement(1501945..1503363) Escherichia coli UMN026 7158102 YP_002412240.1 CDS dhaL NC_011751.1 1503374 1504006 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1503374..1504006) Escherichia coli UMN026 7156156 YP_002412241.1 CDS dhaK NC_011751.1 1504017 1505087 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1504017..1505087) Escherichia coli UMN026 7156158 YP_002412242.1 CDS dhaR NC_011751.1 1505315 1507234 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1505315..1507234 Escherichia coli UMN026 7156157 YP_002412243.1 CDS ycgV NC_011751.1 1507334 1510201 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659678; Product type pf : putative factor; putative adhesin complement(1507334..1510201) Escherichia coli UMN026 7156159 YP_002412244.1 CDS ychF NC_011751.1 1511046 1512137 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1511046..1512137) Escherichia coli UMN026 7158556 YP_002412245.1 CDS pth NC_011751.1 1512254 1512838 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1512254..1512838) Escherichia coli UMN026 7158561 YP_002412246.1 CDS ychH NC_011751.1 1513116 1513394 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1513116..1513394 Escherichia coli UMN026 7157562 YP_002412247.1 CDS ychM NC_011751.1 1513449 1515128 R putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM complement(1513449..1515128) Escherichia coli UMN026 7158562 YP_002412248.1 CDS prsA NC_011751.1 1515253 1516200 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1515253..1516200) Escherichia coli UMN026 7158564 YP_002412249.1 CDS ipk NC_011751.1 1516351 1517202 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1516351..1517202) Escherichia coli UMN026 7157546 YP_002412250.1 CDS lolB NC_011751.1 1517202 1517825 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1517202..1517825) Escherichia coli UMN026 7156865 YP_002412251.1 CDS hemA NC_011751.1 1518039 1519295 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1518039..1519295 Escherichia coli UMN026 7156995 YP_002412252.1 CDS prfA NC_011751.1 1519336 1520418 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1519336..1520418 Escherichia coli UMN026 7156650 YP_002412253.1 CDS prmC NC_011751.1 1520418 1521251 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1520418..1521251 Escherichia coli UMN026 7157517 YP_002412254.1 CDS ychQ NC_011751.1 1521248 1521640 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator; putative transcriptional regulator 1521248..1521640 Escherichia coli UMN026 7157529 YP_002412255.1 CDS ychA NC_011751.1 1521644 1522453 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator; putative transcriptional regulator 1521644..1522453 Escherichia coli UMN026 7158567 YP_002412256.1 CDS kdsA NC_011751.1 1522489 1523343 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1522489..1523343 Escherichia coli UMN026 7158559 YP_002412257.1 CDS ldrB NC_011751.1 1523491 1523598 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; toxic polypeptide, small complement(1523491..1523598) Escherichia coli UMN026 7156895 YP_002412258.1 CDS ldrB NC_011751.1 1524026 1524193 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; small toxic polypeptide complement(1524026..1524193) Escherichia coli UMN026 7157635 YP_002412259.1 CDS chaA NC_011751.1 1524539 1525639 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93266586, 94193576, 94292460; Product type t : transporter; calcium/sodium:proton antiporter complement(1524539..1525639) Escherichia coli UMN026 7157634 YP_002412260.1 CDS chaB NC_011751.1 1525909 1526139 D in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1525909..1526139 Escherichia coli UMN026 7155942 YP_002412261.1 CDS chaC NC_011751.1 1526276 1526992 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator; regulatory protein for cation transport 1526276..1526992 Escherichia coli UMN026 7155943 YP_002412262.1 CDS ychN NC_011751.1 1527036 1527389 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1527036..1527389) Escherichia coli UMN026 7155944 YP_002412263.1 CDS ychP NC_011751.1 1527716 1528969 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pf : putative factor; hypothetical protein 1527716..1528969 Escherichia coli UMN026 7158565 YP_002412264.1 CDS narL NC_011751.1 1528970 1529620 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1528970..1529620) Escherichia coli UMN026 7158566 YP_002412265.1 CDS narX NC_011751.1 1529613 1531409 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92276349, 92374842, 94083940, 2649492, 2657652, 2668029; Product type r : regulator; nitrate/nitrite sensor protein NarX complement(1529613..1531409) Escherichia coli UMN026 7157252 YP_002412266.1 CDS narK NC_011751.1 1531748 1533139 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91258310, 2657652, 2668029; Product type t : transporter; nitrate/nitrite transporter 1531748..1533139 Escherichia coli UMN026 7157258 YP_002412267.1 CDS narG NC_011751.1 1533534 1537277 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 2233673, 2668029, 2995309, 3053688, 3308846, 6094247; Product type e : enzyme; nitrate reductase 1 subunit alpha 1533534..1537277 Escherichia coli UMN026 7157251 YP_002412268.1 CDS narH NC_011751.1 1537274 1538812 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 1321049, 2832376, 3053688, 8383531, 8388253, 8664273, 9516445; Product type c : carrier; nitrate reductase 1, beta (Fe-S) subunit 1537274..1538812 Escherichia coli UMN026 7157247 YP_002412269.1 CDS narJ NC_011751.1 1538809 1539519 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89384449, 92121125, 9632249, 2832376; Product type f : factor; molybdenum-cofactor-assembly chaperone subunit delta 1538809..1539519 Escherichia coli UMN026 7157248 YP_002412270.1 CDS narI NC_011751.1 1539519 1540196 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 75114694, 89384449, 92121125, 2832376, 3053688; Product type c : carrier; nitrate reductase 1, gamma (cytochrome b(NR)) subunit 1539519..1540196 Escherichia coli UMN026 7157250 YP_002412271.1 CDS ECUMN_1528 NC_011751.1 1540555 1541004 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1540555..1541004 Escherichia coli UMN026 7158568 YP_002412272.1 CDS purU NC_011751.1 1541100 1541942 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1541100..1541942) Escherichia coli UMN026 7155639 YP_002412273.1 CDS ychJ NC_011751.1 1541992 1542450 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1541992..1542450) Escherichia coli UMN026 7157585 YP_002412274.1 CDS rssA NC_011751.1 1542563 1543468 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 1542563..1543468 Escherichia coli UMN026 7158563 YP_002412275.1 CDS rssB NC_011751.1 1543560 1544573 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339606, 12912910, 9495753; Product type r : regulator; response regulator of RpoS 1543560..1544573 Escherichia coli UMN026 7157801 YP_002412276.1 CDS galU NC_011751.1 1544775 1545683 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1544775..1545683 Escherichia coli UMN026 7157802 YP_002412277.1 CDS ECUMN_1534 NC_011751.1 1545737 1545925 D Evidence 6 : Doubtful CDS; hypothetical protein 1545737..1545925 Escherichia coli UMN026 7156501 YP_002412278.1 CDS ECUMN_1535 NC_011751.1 1545831 1546340 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group 1545831..1546340 Escherichia coli UMN026 7154967 YP_002412279.1 CDS hns NC_011751.1 1546540 1546953 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 94335643, 95267838, 95286558, 99355427, 2404280, 11298273; Product type r : regulator; global DNA-binding transcriptional dual regulator H-NS complement(1546540..1546953) Escherichia coli UMN026 7154968 YP_002412280.1 CDS tdk NC_011751.1 1547557 1548174 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1547557..1548174 Escherichia coli UMN026 7156690 YP_002412281.1 CDS adhE NC_011751.1 1548477 1551152 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12783863, 4301680, 89291706, 91200315; Product type e : enzyme; bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1548477..1551152) Escherichia coli UMN026 7158044 YP_002412282.1 CDS ychE NC_011751.1 1551629 1552276 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1551629..1552276 Escherichia coli UMN026 7155698 YP_002412283.1 CDS oppA NC_011751.1 1553014 1554645 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20256410, 86111605, 90256748, 92325017, 2015910, 9298646, 9600841, 2187863, 8740179, 9740056, 10972807; Product type t : transporter; oligopeptide ABC transporter periplasmic-binding protein 1553014..1554645 Escherichia coli UMN026 7158560 YP_002412284.1 CDS oppB NC_011751.1 1554731 1555651 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606, 93106975, 2187863; Product type t : transporter; oligopeptide transporter permease 1554731..1555651 Escherichia coli UMN026 7157357 YP_002412285.1 CDS oppC NC_011751.1 1555666 1556574 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter membrane protein 1555666..1556574 Escherichia coli UMN026 7157358 YP_002412286.1 CDS oppD NC_011751.1 1556586 1557599 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide transporter ATP-binding component 1556586..1557599 Escherichia coli UMN026 7157359 YP_002412287.1 CDS oppF NC_011751.1 1557596 1558600 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter ATP-binding protein 1557596..1558600 Escherichia coli UMN026 7157360 YP_002412288.1 CDS yciU NC_011751.1 1558653 1558982 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1558653..1558982) Escherichia coli UMN026 7157361 YP_002412289.1 CDS cls NC_011751.1 1559017 1560477 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1559017..1560477) Escherichia coli UMN026 7158583 YP_002412290.1 CDS ECUMN_1547 NC_011751.1 1560509 1560793 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1560509..1560793 Escherichia coli UMN026 7155983 YP_002412291.1 CDS ECUMN_1548 NC_011751.1 1560739 1560906 D Evidence 6 : Doubtful CDS; hypothetical protein 1560739..1560906 Escherichia coli UMN026 7154969 YP_002412292.1 CDS kch NC_011751.1 1560848 1562101 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12220501, 12912904, 94224769, 98319474; Product type t : transporter; voltage-gated potassium channel complement(1560848..1562101) Escherichia coli UMN026 7154970 YP_002412293.1 CDS yciI NC_011751.1 1562402 1562698 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(1562402..1562698) Escherichia coli UMN026 7156886 YP_002412294.1 CDS tonB NC_011751.1 1562922 1563641 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1562922..1563641 Escherichia coli UMN026 7158576 YP_002412295.1 CDS yciA NC_011751.1 1563681 1564079 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1563681..1564079) Escherichia coli UMN026 7158086 YP_002412296.1 CDS yciB NC_011751.1 1564184 1564723 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1564184..1564723) Escherichia coli UMN026 7158569 YP_002412297.1 CDS yciC NC_011751.1 1564753 1565496 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1564753..1565496) Escherichia coli UMN026 7158570 YP_002412298.1 CDS ompW NC_011751.1 1565853 1566491 D receptor for colicin S4; outer membrane protein W 1565853..1566491 Escherichia coli UMN026 7158571 YP_002412299.1 CDS yciE NC_011751.1 1566551 1567057 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15388941, 3058546, 8455549; hypothetical protein complement(1566551..1567057) Escherichia coli UMN026 7157351 YP_002412300.1 CDS yciF NC_011751.1 1567103 1567603 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3058546, 8455549; hypothetical protein complement(1567103..1567603) Escherichia coli UMN026 7158572 YP_002412301.1 CDS yciG NC_011751.1 1567689 1567868 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1567689..1567868) Escherichia coli UMN026 7158573 YP_002412302.1 CDS trpA NC_011751.1 1568249 1569055 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1568249..1569055) Escherichia coli UMN026 7158574 YP_002412303.1 CDS trpB NC_011751.1 1569055 1570248 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1569055..1570248) Escherichia coli UMN026 7158117 YP_002412304.1 CDS trpC NC_011751.1 1570260 1571618 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1570260..1571618) Escherichia coli UMN026 7158118 YP_002412305.1 CDS trpD NC_011751.1 1571622 1573217 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1571622..1573217) Escherichia coli UMN026 7158119 YP_002412306.1 CDS trpE NC_011751.1 1573217 1574779 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1573217..1574779) Escherichia coli UMN026 7158120 YP_002412308.1 CDS yciV NC_011751.1 1575053 1575934 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1575053..1575934 Escherichia coli UMN026 7158122 YP_002412309.1 CDS yciO NC_011751.1 1575931 1576551 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1575931..1576551 Escherichia coli UMN026 7158584 YP_002412310.1 CDS yciQ NC_011751.1 1576579 1578474 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1576579..1578474 Escherichia coli UMN026 7158580 YP_002412311.1 CDS rluB NC_011751.1 1578685 1579560 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1578685..1579560 Escherichia coli UMN026 7158581 YP_002412312.1 CDS btuR NC_011751.1 1579600 1580190 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1579600..1580190) Escherichia coli UMN026 7157700 YP_002412313.1 CDS yciK NC_011751.1 1580187 1580945 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; short chain dehydrogenase complement(1580187..1580945) Escherichia coli UMN026 7155899 YP_002412314.1 CDS sohB NC_011751.1 1581165 1582214 D SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1581165..1582214 Escherichia coli UMN026 7158577 YP_002412315.1 CDS yciN NC_011751.1 1582250 1582501 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029379, 7567469, 9868784; hypothetical protein complement(1582250..1582501) Escherichia coli UMN026 7157949 YP_002412316.1 CDS ECUMN_1572 NC_011751.1 1582546 1582758 D Evidence 6 : Doubtful CDS; hypothetical protein 1582546..1582758 Escherichia coli UMN026 7158579 YP_002412317.1 CDS topA NC_011751.1 1582881 1585478 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1582881..1585478 Escherichia coli UMN026 7154971 YP_002412318.1 CDS cysB NC_011751.1 1585688 1586662 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1585688..1586662 Escherichia coli UMN026 7158087 YP_002412319.1 CDS ECUMN_1575 NC_011751.1 1586957 1587121 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1586957..1587121 Escherichia coli UMN026 7156079 YP_002412320.1 CDS ECUMN_1576 NC_011751.1 1587103 1587291 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1587103..1587291 Escherichia coli UMN026 7154972 YP_002412321.1 CDS ECUMN_1577 NC_011751.1 1587428 1587610 D Evidence 6 : Doubtful CDS; hypothetical protein 1587428..1587610 Escherichia coli UMN026 7154973 YP_002412322.1 CDS acnA NC_011751.1 1587664 1590339 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1587664..1590339 Escherichia coli UMN026 7154974 YP_002412323.1 CDS ribA NC_011751.1 1590403 1590993 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1590403..1590993) Escherichia coli UMN026 7155681 YP_002412324.1 CDS pgpB NC_011751.1 1591163 1591927 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033893, 92104964; Product type e : enzyme; phosphatidylglycerophosphatase B 1591163..1591927 Escherichia coli UMN026 7157682 YP_002412325.1 CDS yciS NC_011751.1 1592076 1592384 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1592076..1592384 Escherichia coli UMN026 7157431 YP_002412326.1 CDS yciM NC_011751.1 1592391 1593560 D Evidence 4 : Homologs of previously reported genes of unknown function; tetratricopeptide repeat-containing protein 1592391..1593560 Escherichia coli UMN026 7158582 YP_002412327.1 CDS pyrF NC_011751.1 1593752 1594489 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1593752..1594489 Escherichia coli UMN026 7158578 YP_002412328.1 CDS yciH NC_011751.1 1594489 1594815 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1594489..1594815 Escherichia coli UMN026 7157601 YP_002412329.1 CDS osmB NC_011751.1 1594941 1595159 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 2644204; Product type lp : lipoprotein; lipoprotein complement(1594941..1595159) Escherichia coli UMN026 7158575 YP_002412330.1 CDS deoT NC_011751.1 1595428 1596177 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16451192; Product type r : regulator; DNA-binding transcriptional repressor complement(1595428..1596177) Escherichia coli UMN026 7157363 YP_002412331.1 CDS ECUMN_1588 NC_011751.1 1596267 1596482 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1596267..1596482) Escherichia coli UMN026 7156145 YP_002412332.1 CDS gmr NC_011751.1 1596587 1598572 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1596587..1598572) Escherichia coli UMN026 7154975 YP_002412333.1 CDS rnb NC_011751.1 1598807 1600741 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1598807..1600741) Escherichia coli UMN026 7156591 YP_002412334.1 CDS yciW NC_011751.1 1600809 1601936 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidase or amidotransferase complement(1600809..1601936) Escherichia coli UMN026 7157707 YP_002412335.1 CDS fabI NC_011751.1 1602080 1602868 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(1602080..1602868) Escherichia coli UMN026 7158585 YP_002412336.1 CDS ECUMN_1593 NC_011751.1 1603038 1603205 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1603038..1603205) Escherichia coli UMN026 7156299 YP_002412337.1 CDS ycjD NC_011751.1 1603252 1603617 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1603252..1603617) Escherichia coli UMN026 7154976 YP_002412338.1 CDS sapF NC_011751.1 1603685 1604491 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein transporter complement(1603685..1604491) Escherichia coli UMN026 7158586 YP_002412339.1 CDS sapD NC_011751.1 1604493 1605485 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580, 1987159; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein complement(1604493..1605485) Escherichia coli UMN026 7157869 YP_002412340.1 CDS sapC NC_011751.1 1605485 1606375 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease complement(1605485..1606375) Escherichia coli UMN026 7157868 YP_002412341.1 CDS sapB NC_011751.1 1606362 1607327 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease complement(1606362..1607327) Escherichia coli UMN026 7157867 YP_002412342.1 CDS sapA NC_011751.1 1607324 1608967 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter periplasmic-binding protein complement(1607324..1608967) Escherichia coli UMN026 7157866 YP_002412343.1 CDS ECUMN_1600 NC_011751.1 1609010 1609210 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1609010..1609210) Escherichia coli UMN026 7157865 YP_002412344.1 CDS ymjA NC_011751.1 1609280 1609525 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1609280..1609525) Escherichia coli UMN026 7154977 YP_002412345.1 CDS puuP NC_011751.1 1609659 1611044 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15590624; Product type t : transporter; putrescine importer complement(1609659..1611044) Escherichia coli UMN026 7159493 YP_002412346.1 CDS puuA NC_011751.1 1611347 1612765 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15590624; Product type e : enzyme; gamma-Glu-putrescine synthase complement(1611347..1612765) Escherichia coli UMN026 7157593 YP_002412347.1 CDS puuD NC_011751.1 1612977 1613741 D catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1612977..1613741 Escherichia coli UMN026 7157588 YP_002412348.1 CDS puuR NC_011751.1 1613768 1614325 D regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1613768..1614325 Escherichia coli UMN026 7157591 YP_002412349.1 CDS puuC NC_011751.1 1614475 1615962 D catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1614475..1615962 Escherichia coli UMN026 7157594 YP_002412350.1 CDS puuB NC_011751.1 1615964 1617244 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150200, 15590624; Product type e : enzyme; gamma-Glu-putrescine oxidase 1615964..1617244 Escherichia coli UMN026 7157590 YP_002412351.1 CDS puuE NC_011751.1 1617282 1618547 D putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1617282..1618547 Escherichia coli UMN026 7157589 YP_002412352.1 CDS pspF NC_011751.1 1618667 1619644 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1618667..1619644) Escherichia coli UMN026 7157592 YP_002412353.1 CDS pspA NC_011751.1 1619811 1620479 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1619811..1620479 Escherichia coli UMN026 7157555 YP_002412354.1 CDS pspB NC_011751.1 1620533 1620757 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1620533..1620757 Escherichia coli UMN026 7157550 YP_002412355.1 CDS pspC NC_011751.1 1620757 1621116 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1620757..1621116 Escherichia coli UMN026 7157551 YP_002412356.1 CDS pspD NC_011751.1 1621125 1621346 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295203, 97303082; Product type ph : phenotype; peripheral inner membrane phage-shock protein 1621125..1621346 Escherichia coli UMN026 7157552 YP_002412357.1 CDS pspE NC_011751.1 1621421 1621735 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1621421..1621735 Escherichia coli UMN026 7157553 YP_002412358.1 CDS ycjX NC_011751.1 1621854 1623251 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1621854..1623251 Escherichia coli UMN026 7157554 YP_002412359.1 CDS ycjF NC_011751.1 1623248 1624309 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1623248..1624309 Escherichia coli UMN026 7158589 YP_002412360.1 CDS tyrR NC_011751.1 1624457 1625998 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1624457..1625998 Escherichia coli UMN026 7158587 YP_002412361.1 CDS tpx NC_011751.1 1626042 1626548 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1626042..1626548) Escherichia coli UMN026 7158150 YP_002412362.1 CDS ycjG NC_011751.1 1626667 1627632 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11747447, 11747448, 7499381; Product type e : enzyme; L-Ala-D/L-Glu epimerase 1626667..1627632 Escherichia coli UMN026 7158101 YP_002412363.1 CDS mpaA NC_011751.1 1627607 1628395 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12511517; Product type e : enzyme; murein peptide amidase A complement(1627607..1628395) Escherichia coli UMN026 7158588 YP_002412364.1 CDS ymjC NC_011751.1 1628626 1629264 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P) binding enzyme complement(1628626..1629264) Escherichia coli UMN026 7157164 YP_002412365.1 CDS ycjY NC_011751.1 1629335 1630267 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase complement(1629335..1630267) Escherichia coli UMN026 7159494 YP_002412366.1 CDS ycjZ NC_011751.1 1630393 1631292 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pr : putative regulator; putative nucleic acid-binding regulator 1630393..1631292 Escherichia coli UMN026 7158590 YP_002412367.1 CDS mppA NC_011751.1 1631629 1633242 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438753, 9495761; Product type t : transporter; murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) ABC transporter periplasmic-binding protein 1631629..1633242 Escherichia coli UMN026 7158591 YP_002412368.1 CDS ynaI NC_011751.1 1633293 1634324 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1633293..1634324) Escherichia coli UMN026 7157168 YP_002412369.1 CDS ynaJ NC_011751.1 1634568 1634825 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1634568..1634825 Escherichia coli UMN026 7159495 YP_002412370.1 CDS uspE NC_011751.1 1634875 1635825 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1634875..1635825) Escherichia coli UMN026 7159496 YP_002412371.1 CDS fnr NC_011751.1 1635977 1636729 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1635977..1636729) Escherichia coli UMN026 7158194 YP_002412372.1 CDS ogt NC_011751.1 1636924 1637439 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88067749, 91161525, 94252990, 98125595, 1520330; Product type e : enzyme; O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1636924..1637439) Escherichia coli UMN026 7156420 YP_002412373.1 CDS abgT NC_011751.1 1637450 1638976 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9829935, 2825131, 7567469; Product type t : transporter; putative aminobenzoyl-glutamate transporter complement(1637450..1638976) Escherichia coli UMN026 7157343 YP_002412374.1 CDS ECUMN_1632 NC_011751.1 1638906 1639100 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1638906..1639100) Escherichia coli UMN026 7155669 YP_002412375.1 CDS abgB NC_011751.1 1639013 1640458 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9829935; Product type pe : putative enzyme; putative peptidase, aminobenzoyl-glutamate utilization protein complement(1639013..1640458) Escherichia coli UMN026 7154978 YP_002412376.1 CDS abgA NC_011751.1 1640458 1641768 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9829935; Product type pe : putative enzyme; putative peptidase, para-aminobenzoyl-glutamate utilization protein complement(1640458..1641768) Escherichia coli UMN026 7155667 YP_002412377.1 CDS abgR NC_011751.1 1641944 1642852 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9829935; Product type r : regulator; putative DNA-binding transcriptional regulator 1641944..1642852 Escherichia coli UMN026 7155666 YP_002412378.1 CDS ydaL NC_011751.1 1643182 1643745 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1643182..1643745 Escherichia coli UMN026 7156870 YP_002412379.1 CDS ydaM NC_011751.1 1643766 1644998 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16045609; Product type pe : putative enzyme; putative diguanylate cyclase, GG[D/E]EF domain signalling protein complement(1643766..1644998) Escherichia coli UMN026 7158592 YP_002412380.1 CDS zntB NC_011751.1 1645253 1646236 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; zinc transporter 1645253..1646236 Escherichia coli UMN026 7158593 YP_002412381.1 CDS ECUMN_1639 NC_011751.1 1646512 1646685 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1646512..1646685 Escherichia coli UMN026 7158594 YP_002412382.1 CDS dbpA NC_011751.1 1646715 1648088 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1646715..1648088 Escherichia coli UMN026 7155903 YP_002412383.1 CDS ydaO NC_011751.1 1648217 1649152 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1648217..1649152) Escherichia coli UMN026 7156112 YP_002412384.1 CDS uspF NC_011751.1 1649328 1649762 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12381839, 11849540, 9298646; Product type f : factor; stress-induced protein, ATP-binding protein complement(1649328..1649762) Escherichia coli UMN026 7158595 YP_002412385.1 CDS ompN NC_011751.1 1649903 1651036 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642192; Product type t : transporter; outer membrane pore protein N, non-specific complement(1649903..1651036) Escherichia coli UMN026 7158195 YP_002412386.1 CDS ydbK NC_011751.1 1651398 1654922 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9025293; Product type pe : putative enzyme; putative 2-oxoacid-flavodoxin complement(1651398..1654922) Escherichia coli UMN026 7157131 YP_002412387.1 CDS ydbJ NC_011751.1 1655196 1655462 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1655196..1655462 Escherichia coli UMN026 7158601 YP_002412388.1 CDS hslJ NC_011751.1 1655459 1655881 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12892888, 8349564, 9025293; Product type f : factor; heat-inducible protein complement(1655459..1655881) Escherichia coli UMN026 7158600 YP_002412389.1 CDS ldhA NC_011751.1 1655992 1656981 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4297266, 89123040, 90198524, 8349564, 9025293; Product type e : enzyme; fermentative D-lactate dehydrogenase complement(1655992..1656981) Escherichia coli UMN026 7156720 YP_002412390.1 CDS ydbH NC_011751.1 1657189 1659828 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1657189..1659828 Escherichia coli UMN026 7156937 YP_002412391.1 CDS ynbE NC_011751.1 1659825 1660010 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 1659825..1660010 Escherichia coli UMN026 7158599 YP_002412392.1 CDS ydbL NC_011751.1 1660018 1660341 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1660018..1660341 Escherichia coli UMN026 7159501 YP_002412393.1 CDS ydbA NC_011751.1 1660767 1666586 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative autotransported outer membrane protein involved in cell adhesion 1660767..1666586 Escherichia coli UMN026 7158602 YP_002412394.1 CDS ydbC NC_011751.1 1666794 1667654 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 1666794..1667654 Escherichia coli UMN026 7158596 YP_002412395.1 CDS ydbD NC_011751.1 1667718 1670024 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1667718..1670024 Escherichia coli UMN026 7158597 YP_002412396.1 CDS ynbA NC_011751.1 1670193 1670798 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1670193..1670798 Escherichia coli UMN026 7158598 YP_002412397.1 CDS ynbB NC_011751.1 1670798 1671694 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane associated CTP-phosphosubstrate transferase 1670798..1671694 Escherichia coli UMN026 7159497 YP_002412398.1 CDS ynbC NC_011751.1 1671710 1673467 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 1671710..1673467 Escherichia coli UMN026 7159498 YP_002412399.1 CDS ynbD NC_011751.1 1673481 1674773 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane associated phosphatase 1673481..1674773 Escherichia coli UMN026 7159499 YP_002412400.1 CDS azoR NC_011751.1 1674827 1675432 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1674827..1675432) Escherichia coli UMN026 7159500 YP_002412401.1 CDS hrpA NC_011751.1 1675690 1679535 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1675690..1679535 Escherichia coli UMN026 7155845 YP_002412402.1 CDS ECUMN_1661 NC_011751.1 1679937 1680431 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1679937..1680431) Escherichia coli UMN026 7156712 YP_002412403.1 CDS ydcF NC_011751.1 1680821 1681621 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1680821..1681621 Escherichia coli UMN026 7154980 YP_002412404.1 CDS aldA NC_011751.1 1681818 1683257 D NAD-linked; aldehyde dehydrogenase A 1681818..1683257 Escherichia coli UMN026 7158604 YP_002412405.1 CDS gapC NC_011751.1 1683299 1684300 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9622357, 9019141, 1917845, 3780374; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase C complement(1683299..1684300) Escherichia coli UMN026 7155722 YP_002412406.1 CDS cybB NC_011751.1 1684489 1685019 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1684489..1685019 Escherichia coli UMN026 7156504 YP_002412407.1 CDS ydcA NC_011751.1 1685264 1685437 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1685264..1685437 Escherichia coli UMN026 7157838 YP_002412408.1 CDS mokB NC_011751.1 1685549 1685716 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type r : regulator; regulatory peptide complement(1685549..1685716) Escherichia coli UMN026 7158603 YP_002412409.1 CDS trg NC_011751.1 1686048 1687688 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90008892, 92390356, 93259131, 6374654; Product type r : regulator; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1686048..1687688 Escherichia coli UMN026 7157950 YP_002412410.1 CDS ydcI NC_011751.1 1687727 1688650 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(1687727..1688650) Escherichia coli UMN026 7158107 YP_002412411.1 CDS ydcJ NC_011751.1 1688867 1690210 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1688867..1690210 Escherichia coli UMN026 7158606 YP_002412412.1 CDS mdoD NC_011751.1 1690465 1692090 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1690465..1692090 Escherichia coli UMN026 7158607 YP_002412413.1 CDS ECUMN_1673 NC_011751.1 1692011 1692214 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1692011..1692214) Escherichia coli UMN026 7157074 YP_002412414.1 CDS ydcH NC_011751.1 1692230 1692454 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1692230..1692454 Escherichia coli UMN026 7154981 YP_002412415.1 CDS rimL NC_011751.1 1692517 1693056 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89364711; Product type e : enzyme; ribosomal-protein-L7/L12-serine acetyltransferase 1692517..1693056 Escherichia coli UMN026 7158605 YP_002412416.1 CDS ydcK NC_011751.1 1693048 1694028 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(1693048..1694028) Escherichia coli UMN026 7157694 YP_002412417.1 CDS tehA NC_011751.1 1694152 1695144 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94222856, 2060788; Product type t : transporter; potassium-tellurite ethidium and proflavin transporter 1694152..1695144 Escherichia coli UMN026 7158608 YP_002412418.1 CDS tehB NC_011751.1 1695141 1695734 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1695141..1695734 Escherichia coli UMN026 7158045 YP_002412419.1 CDS ydcL NC_011751.1 1696036 1696704 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 1696036..1696704 Escherichia coli UMN026 7158046 YP_002412420.1 CDS ydcO NC_011751.1 1696739 1698034 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1885518; Product type pt : putative transporter; putative benzoate transporter complement(1696739..1698034) Escherichia coli UMN026 7158609 YP_002412421.1 CDS ydcN NC_011751.1 1698003 1698539 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1698003..1698539 Escherichia coli UMN026 7158613 YP_002412422.1 CDS ydcP NC_011751.1 1698612 1700573 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 1698612..1700573 Escherichia coli UMN026 7158612 YP_002412423.1 CDS yncJ NC_011751.1 1700665 1700895 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1700665..1700895) Escherichia coli UMN026 7158614 YP_002412424.1 CDS yncN NC_011751.1 1701117 1701293 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1701117..1701293 Escherichia coli UMN026 7159508 YP_002412425.1 CDS ydcQ NC_011751.1 1701318 1701755 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1701318..1701755 Escherichia coli UMN026 7159509 YP_002412426.1 CDS ydcR NC_011751.1 1701834 1703240 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1701834..1703240 Escherichia coli UMN026 7158615 YP_002412427.1 CDS ydcS NC_011751.1 1703485 1704630 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11683869; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter periplasmic-binding protein 1703485..1704630 Escherichia coli UMN026 7158616 YP_002412428.1 CDS ydcT NC_011751.1 1704648 1705661 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter ATP-binding protein 1704648..1705661 Escherichia coli UMN026 7158617 YP_002412429.1 CDS ydcU NC_011751.1 1705662 1706603 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter permease 1705662..1706603 Escherichia coli UMN026 7158618 YP_002412430.1 CDS ydcV NC_011751.1 1706593 1707387 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter permease 1706593..1707387 Escherichia coli UMN026 7158619 YP_002412431.1 CDS ydcW NC_011751.1 1707409 1708833 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1707409..1708833 Escherichia coli UMN026 7158620 YP_002412432.1 CDS ECUMN_1693 NC_011751.1 1709056 1709865 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8257133, 11841212, 12771141; Product type pe : putative enzyme; putative acetyltransferase 1709056..1709865 Escherichia coli UMN026 7158621 YP_002412433.1 CDS ydcX NC_011751.1 1710482 1710730 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1710482..1710730 Escherichia coli UMN026 7154982 YP_002412434.1 CDS ydcY NC_011751.1 1710816 1711049 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1710816..1711049 Escherichia coli UMN026 7158622 YP_002412435.1 CDS ydcZ NC_011751.1 1711050 1711499 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1711050..1711499) Escherichia coli UMN026 7158623 YP_002412436.1 CDS yncA NC_011751.1 1711496 1712014 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase complement(1711496..1712014) Escherichia coli UMN026 7158624 YP_002412437.1 CDS yncB NC_011751.1 1712195 1713232 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1712195..1713232 Escherichia coli UMN026 7159502 YP_002412438.1 CDS yncC NC_011751.1 1713430 1714095 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11004173; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1713430..1714095 Escherichia coli UMN026 7159503 YP_002412439.1 CDS yncD NC_011751.1 1714131 1716233 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative iron outer membrane receptor complement(1714131..1716233) Escherichia coli UMN026 7159504 YP_002412440.1 CDS yncE NC_011751.1 1716475 1717536 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1716475..1717536 Escherichia coli UMN026 7159505 YP_002412441.1 CDS ansP NC_011751.1 1717649 1719148 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005443; Product type t : transporter; L-asparagine transporter complement(1717649..1719148) Escherichia coli UMN026 7159506 YP_002412442.1 CDS yncG NC_011751.1 1719415 1720032 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; glutathione S-transferase-like protein 1719415..1720032 Escherichia coli UMN026 7155747 YP_002412443.1 CDS ECUMN_1704 NC_011751.1 1720572 1720856 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1720572..1720856 Escherichia coli UMN026 7159507 YP_002412444.1 CDS ECUMN_1705 NC_011751.1 1720875 1723280 D Evidence 4 : Homologs of previously reported genes of unknown function; putative VgrG/E protein associated with Rhs elements 1720875..1723280 Escherichia coli UMN026 7154990 YP_002412445.1 CDS ECUMN_1706 NC_011751.1 1723234 1724061 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative zinc-dependent metallopeptidase 1723234..1724061 Escherichia coli UMN026 7154991 YP_002412446.1 CDS ECUMN_1707 NC_011751.1 1724085 1724744 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1724085..1724744 Escherichia coli UMN026 7154992 YP_002412447.1 CDS ECUMN_1708 NC_011751.1 1724725 1724907 D Evidence 6 : Doubtful CDS; hypothetical protein 1724725..1724907 Escherichia coli UMN026 7154993 YP_002412448.1 CDS ECUMN_1710 NC_011751.1 1725524 1726084 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1725524..1726084 Escherichia coli UMN026 7159179 YP_002412449.1 CDS ECUMN_1711 NC_011751.1 1726444 1727079 D Evidence 6 : Doubtful CDS; hypothetical protein 1726444..1727079 Escherichia coli UMN026 7154995 YP_002412450.1 CDS ECUMN_1712 NC_011751.1 1727232 1727405 D Evidence 6 : Doubtful CDS; hypothetical protein 1727232..1727405 Escherichia coli UMN026 7154996 YP_002412451.1 CDS yddH NC_011751.1 1727472 1728041 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1727472..1728041) Escherichia coli UMN026 7154997 YP_002412452.1 CDS nhoA NC_011751.1 1728216 1729061 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme; N-hydroxyarylamine O-acetyltransferase 1728216..1729061 Escherichia coli UMN026 7158629 YP_002412453.1 CDS ECUMN_1715 NC_011751.1 1729133 1729663 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 1729133..1729663 Escherichia coli UMN026 7157274 YP_002412454.1 CDS ECUMN_1716 NC_011751.1 1729768 1730490 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 1729768..1730490 Escherichia coli UMN026 7154998 YP_002412455.1 CDS yddE NC_011751.1 1730579 1731472 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14611652, 15103639, 2233673; hypothetical protein complement(1730579..1731472) Escherichia coli UMN026 7154999 YP_002412456.1 CDS narV NC_011751.1 1731551 1732231 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme; nitrate reductase 2 subunit gamma complement(1731551..1732231) Escherichia coli UMN026 7158627 YP_002412457.1 CDS narW NC_011751.1 1732228 1732923 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410, 92186712; Product type f : factor; nitrate reductase 2 subunit delta (assembly subunit) complement(1732228..1732923) Escherichia coli UMN026 7157256 YP_002412458.1 CDS narY NC_011751.1 1732923 1734467 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type c : carrier; nitrate reductase 2 subunit beta complement(1732923..1734467) Escherichia coli UMN026 7157257 YP_002412459.1 CDS narZ NC_011751.1 1734464 1738204 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme; nitrate reductase 2 subunit alpha complement(1734464..1738204) Escherichia coli UMN026 7157259 YP_002412460.1 CDS narU NC_011751.1 1738299 1739687 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95266795, 2233673; Product type t : transporter; nitrate/nitrite transporter complement(1738299..1739687) Escherichia coli UMN026 7157260 YP_002412461.1 CDS ECUMN_1723 NC_011751.1 1739999 1741294 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1739999..1741294) Escherichia coli UMN026 7157255 YP_002412462.1 CDS ECUMN_1724 NC_011751.1 1741317 1742582 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1741317..1742582) Escherichia coli UMN026 7155000 YP_002412463.1 CDS ECUMN_1725 NC_011751.1 1742746 1743846 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; Outer membrane porin protein ompD complement(1742746..1743846) Escherichia coli UMN026 7155001 YP_002412464.1 CDS yddG NC_011751.1 1744105 1744929 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12410826; Product type t : transporter; hypothetical protein complement(1744105..1744929) Escherichia coli UMN026 7155002 YP_002412465.1 CDS fdnG NC_011751.1 1745218 1748265 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-N subunit alpha, nitrate-inducible 1745218..1748265 Escherichia coli UMN026 7158628 YP_002412466.1 CDS fdnH NC_011751.1 1748278 1749162 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005553, 90375017, 92332427, 11884747, 1834669; Product type c : carrier; formate dehydrogenase-N, Fe-S subunit beta, nitrate-inducible 1748278..1749162 Escherichia coli UMN026 7156316 YP_002412467.1 CDS fdnI NC_011751.1 1749155 1749808 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1749155..1749808 Escherichia coli UMN026 7156317 YP_002412468.1 CDS ECUMN_1732 NC_011751.1 1750320 1750598 R Evidence 4 : Homologs of previously reported genes of unknown function; putative plasmid maintenance system killer protein complement(1750320..1750598) Escherichia coli UMN026 7158630 YP_002412469.1 CDS adhP NC_011751.1 1750784 1751794 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1750784..1751794) Escherichia coli UMN026 7155003 YP_002412470.1 CDS sfcA NC_011751.1 1751928 1753625 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1751928..1753625) Escherichia coli UMN026 7155699 YP_002412471.1 CDS bdm NC_011751.1 1754021 1754236 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10498711, 13129944; Product type f : factor; biofilm-dependent modulation protein complement(1754021..1754236) Escherichia coli UMN026 7157903 YP_002412472.1 CDS osmC NC_011751.1 1754581 1755012 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14512736, 91350191, 9298646; Product type m : membrane component; osmotically inducible, stress-inducible membrane protein 1754581..1755012 Escherichia coli UMN026 7155866 YP_002412473.1 CDS ddpF NC_011751.1 1755068 1755994 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-ala ABC transporter ATP-binding protein complement(1755068..1755994) Escherichia coli UMN026 7157364 YP_002412474.1 CDS ddpD NC_011751.1 1755987 1756973 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-ala ABC transporter ATP-binding protein complement(1755987..1756973) Escherichia coli UMN026 7156131 YP_002412475.1 CDS ddpC NC_011751.1 1756970 1757866 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; ATP-dependent peptide transporter membrane subunit complement(1756970..1757866) Escherichia coli UMN026 7156130 YP_002412476.1 CDS ddpB NC_011751.1 1757863 1758885 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-ala ABC transporter membrane protein complement(1757863..1758885) Escherichia coli UMN026 7156129 YP_002412477.1 CDS ddpA NC_011751.1 1758887 1760437 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-a la ABC transporter periplasmic-binding protein complement(1758887..1760437) Escherichia coli UMN026 7156128 YP_002412478.1 CDS ddpX NC_011751.1 1760451 1761032 R catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase complement(1760451..1761032) Escherichia coli UMN026 7156127 YP_002412479.1 CDS dos NC_011751.1 1761290 1763689 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1761290..1763689) Escherichia coli UMN026 7156132 YP_002412480.1 CDS yddV NC_011751.1 1763714 1764757 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase complement(1763714..1764757) Escherichia coli UMN026 7156194 YP_002412481.1 CDS yddW NC_011751.1 1765472 1766791 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10960106; Product type lp : lipoprotein; putative lipoprotein complement(1765472..1766791) Escherichia coli UMN026 7158631 YP_002412482.1 CDS gadC NC_011751.1 1766922 1768457 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15795232, 15489450; Product type t : transporter; glutamate:gamma-aminobutyric acid antiporter complement(1766922..1768457) Escherichia coli UMN026 7158632 YP_002412483.1 CDS gadB NC_011751.1 1768613 1770013 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12912902, 92155241, 92394884, 99406302, 8455549; Product type e : enzyme; glutamate decarboxylase B, PLP-dependent complement(1768613..1770013) Escherichia coli UMN026 7156488 YP_002412484.1 CDS pqqL NC_011751.1 1770376 1773171 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1659611, 11514505; Product type pe : putative enzyme; putative membrane-associated peptidase complement(1770376..1773171) Escherichia coli UMN026 7156487 YP_002412485.1 CDS yddB NC_011751.1 1773216 1775588 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative porin protein complement(1773216..1775588) Escherichia coli UMN026 7157515 YP_002412486.1 CDS yddA NC_011751.1 1775626 1777311 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative multidrug ABC transporter permease/ATP-binding protein complement(1775626..1777311) Escherichia coli UMN026 7158626 YP_002412487.1 CDS ydeM NC_011751.1 1777602 1778759 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pr : putative regulator; hypothetical protein complement(1777602..1778759) Escherichia coli UMN026 7158625 YP_002412488.1 CDS ydeN NC_011751.1 1778811 1780493 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfatase complement(1778811..1780493) Escherichia coli UMN026 7158637 YP_002412489.1 CDS ydeO NC_011751.1 1780896 1781657 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1780896..1781657) Escherichia coli UMN026 7158638 YP_002412490.1 CDS ECUMN_1754 NC_011751.1 1781732 1781965 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1781732..1781965) Escherichia coli UMN026 7158639 YP_002412491.1 CDS ydeP NC_011751.1 1782177 1784456 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase complement(1782177..1784456) Escherichia coli UMN026 7155004 YP_002412492.1 CDS ydeQ NC_011751.1 1784789 1785703 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like exported adhesin protein complement(1784789..1785703) Escherichia coli UMN026 7158640 YP_002412493.1 CDS ydeR NC_011751.1 1785762 1786265 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin exported protein complement(1785762..1786265) Escherichia coli UMN026 7158641 YP_002412494.1 CDS ydeS NC_011751.1 1786278 1786808 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin exported protein complement(1786278..1786808) Escherichia coli UMN026 7158642 YP_002412495.1 CDS ECUMN_1759 NC_011751.1 1786822 1789473 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative fimbrial outer membrane usher protein complement(1786822..1789473) Escherichia coli UMN026 7158643 YP_002412496.1 CDS ECUMN_1760 NC_011751.1 1789515 1790234 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; Periplasmic chaperone complement(1789515..1790234) Escherichia coli UMN026 7155005 YP_002412497.1 CDS ECUMN_1761 NC_011751.1 1790588 1791199 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative major fimbrial subunit FmlA complement(1790588..1791199) Escherichia coli UMN026 7155006 YP_002412498.1 CDS ECUMN_1762 NC_011751.1 1791585 1791839 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative HTH-type transcriptional regulator yqhC (fragment) complement(1791585..1791839) Escherichia coli UMN026 7155007 YP_002412499.1 CDS ECUMN_1763 NC_011751.1 1792254 1793057 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carboxymuconolactone decarboxylase complement(1792254..1793057) Escherichia coli UMN026 7155008 YP_002412500.1 CDS ECUMN_1764 NC_011751.1 1793073 1793798 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative lipoprotein complement(1793073..1793798) Escherichia coli UMN026 7155009 YP_002412501.1 CDS ECUMN_1766 NC_011751.1 1793914 1794933 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Aryl-alcohol dehydrogenase (NADP(+)) complement(1793914..1794933) Escherichia coli UMN026 7155010 YP_002412502.1 CDS ECUMN_1767 NC_011751.1 1794936 1795508 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)H oxidoreductase complement(1794936..1795508) Escherichia coli UMN026 7155011 YP_002412503.1 CDS ECUMN_1768 NC_011751.1 1795659 1795850 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1795659..1795850) Escherichia coli UMN026 7155012 YP_002412504.1 CDS ECUMN_1769 NC_011751.1 1795801 1796271 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1795801..1796271) Escherichia coli UMN026 7155013 YP_002412505.1 CDS ECUMN_1770 NC_011751.1 1796180 1796350 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1796180..1796350) Escherichia coli UMN026 7155014 YP_002412506.1 CDS ECUMN_1771 NC_011751.1 1796438 1797385 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Tas protein complement(1796438..1797385) Escherichia coli UMN026 7155015 YP_002412507.1 CDS ECUMN_1772 NC_011751.1 1797459 1798160 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1797459..1798160) Escherichia coli UMN026 7155016 YP_002412508.1 CDS ECUMN_1773 NC_011751.1 1798157 1798468 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1798157..1798468) Escherichia coli UMN026 7155017 YP_002412509.1 CDS ECUMN_1774 NC_011751.1 1798605 1799504 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-family transcriptional regulator 1798605..1799504 Escherichia coli UMN026 7155018 YP_002412510.1 CDS ECUMN_1775 NC_011751.1 1799748 1799891 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1799748..1799891) Escherichia coli UMN026 7155019 YP_002412511.1 CDS hipA NC_011751.1 1799902 1801224 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765; Product type r : regulator; regulator with hipB complement(1799902..1801224) Escherichia coli UMN026 7155020 YP_002412512.1 CDS hipB NC_011751.1 1801224 1801490 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765, 8021189; Product type r : regulator; DNA-binding transcriptional regulator HipB complement(1801224..1801490) Escherichia coli UMN026 7156671 YP_002412513.1 CDS ECUMN_1778 NC_011751.1 1801701 1807121 R Evidence 4 : Homologs of previously reported genes of unknown function; putative lipoprotein/autotransporter domain-containing protein complement(1801701..1807121) Escherichia coli UMN026 7156672 YP_002412514.1 CDS lsrK NC_011751.1 1807643 1809235 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15601708, 14622426; Product type e : enzyme; autoinducer-2 (AI-2) kinase complement(1807643..1809235) Escherichia coli UMN026 7155021 YP_002412515.1 CDS lsrR NC_011751.1 1809314 1810267 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16321939, 15601708, 14622426; Product type r : regulator; DNA-binding transcriptional regulator complement(1809314..1810267) Escherichia coli UMN026 7157025 YP_002412516.1 CDS ego NC_011751.1 1810516 1812051 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12657059, 11722742; Product type t : transporter; AI2 ABC transporter ATP-binding protein 1810516..1812051 Escherichia coli UMN026 7157026 YP_002412517.1 CDS lsrC NC_011751.1 1812045 1813073 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein 1812045..1813073 Escherichia coli UMN026 7156232 YP_002412518.1 CDS lsrD NC_011751.1 1813073 1814065 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein 1813073..1814065 Escherichia coli UMN026 7157021 YP_002412519.1 CDS lsrB NC_011751.1 1814077 1815099 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter periplasmic-binding protein 1814077..1815099 Escherichia coli UMN026 7157022 YP_002412520.1 CDS lsrF NC_011751.1 1815126 1816001 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; aldolase 1815126..1816001 Escherichia coli UMN026 7157020 YP_002412521.1 CDS lsrG NC_011751.1 1816025 1816315 D Evidence 4 : Homologs of previously reported genes of unknown function; autoinducer-2 (AI-2) modifying protein LsrG 1816025..1816315 Escherichia coli UMN026 7157023 YP_002412522.1 CDS tam NC_011751.1 1816372 1817130 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1816372..1817130 Escherichia coli UMN026 7157024 YP_002412523.1 CDS yneE NC_011751.1 1817134 1818048 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1817134..1818048) Escherichia coli UMN026 7158021 YP_002412524.1 CDS uxaB NC_011751.1 1818245 1819696 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(1818245..1819696) Escherichia coli UMN026 7159510 YP_002412525.1 CDS yneF NC_011751.1 1819923 1821341 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated diguanylate cyclase (GGDEF domain) complement(1819923..1821341) Escherichia coli UMN026 7158204 YP_002412526.1 CDS yneG NC_011751.1 1821480 1821839 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1821480..1821839) Escherichia coli UMN026 7159511 YP_002412527.1 CDS yneH NC_011751.1 1821839 1822765 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1821839..1822765) Escherichia coli UMN026 7159512 YP_002412528.1 CDS yneI NC_011751.1 1822829 1824217 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate semialdehyde dehydrogenase complement(1822829..1824217) Escherichia coli UMN026 7159513 YP_002412529.1 CDS yneJ NC_011751.1 1824318 1825193 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1824318..1825193 Escherichia coli UMN026 7159514 YP_002412530.1 CDS yneK NC_011751.1 1825277 1826392 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1825277..1826392 Escherichia coli UMN026 7159515 YP_002412531.1 CDS ydeA NC_011751.1 1826542 1827732 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094697, 99369894, 8383113, 10438792; Product type t : transporter; sugar efflux transporter 1826542..1827732 Escherichia coli UMN026 7159516 YP_002412532.1 CDS marC NC_011751.1 1827757 1828422 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1827757..1828422) Escherichia coli UMN026 7158633 YP_002412533.1 CDS marR NC_011751.1 1828634 1829068 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1828634..1829068 Escherichia coli UMN026 7157062 YP_002412534.1 CDS marA NC_011751.1 1829088 1829471 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1829088..1829471 Escherichia coli UMN026 7157063 YP_002412535.1 CDS marB NC_011751.1 1829503 1829721 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8383113; hypothetical protein 1829503..1829721 Escherichia coli UMN026 7157060 YP_002412536.1 CDS eamA NC_011751.1 1829752 1830651 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20305052; Product type t : transporter; O-acetylserine/cysteine export protein complement(1829752..1830651) Escherichia coli UMN026 7157061 YP_002412537.1 CDS ydeE NC_011751.1 1830846 1832033 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE 1830846..1832033 Escherichia coli UMN026 7156218 YP_002412538.1 CDS ydeH NC_011751.1 1832474 1833364 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1832474..1833364) Escherichia coli UMN026 7158634 YP_002412539.1 CDS ydeI NC_011751.1 1833619 1834011 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1833619..1834011) Escherichia coli UMN026 7158635 YP_002412540.1 CDS dcp NC_011751.1 1834376 1836421 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 216006, 8226676; Product type e : enzyme; dipeptidyl carboxypeptidase II complement(1834376..1836421) Escherichia coli UMN026 7158636 YP_002412541.1 CDS ydfG NC_011751.1 1836558 1837304 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1836558..1837304 Escherichia coli UMN026 7156115 YP_002412542.1 CDS ydfH NC_011751.1 1837393 1838079 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1837393..1838079 Escherichia coli UMN026 7158646 YP_002412543.1 CDS ydfZ NC_011751.1 1838256 1838459 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12084818; Product type pc : putative carrier; putative selenium carrying protein 1838256..1838459 Escherichia coli UMN026 7158647 YP_002412544.1 CDS ydfI NC_011751.1 1838495 1839955 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mannonate dehydrogenase complement(1838495..1839955) Escherichia coli UMN026 7158658 YP_002412545.1 CDS ydfJ NC_011751.1 1840045 1841328 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(1840045..1841328) Escherichia coli UMN026 7158648 YP_002412546.1 CDS ydfK NC_011751.1 1842081 1842347 D Evidence 4 : Homologs of previously reported genes of unknown function; putative DNA-binding transcriptional regulator; Qin prophage 1842081..1842347 Escherichia coli UMN026 7158649 YP_002412547.1 CDS pinR NC_011751.1 1842664 1843254 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14687564; Product type pe : putative enzyme; putative site-specific recombinase; DNA invertase; Rac prophage 1842664..1843254 Escherichia coli UMN026 7158650 YP_002412548.1 CDS tfaQ NC_011751.1 1843352 1843927 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative tail fiber chaperone; Qin prophage complement(1843352..1843927) Escherichia coli UMN026 7157467 YP_002412549.1 CDS ECUMN_1814 NC_011751.1 1843927 1846848 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber protein complement(1843927..1846848) Escherichia coli UMN026 7158050 YP_002412550.1 CDS ECUMN_1815 NC_011751.1 1846907 1847506 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Lom-like outer membrane protein of phage origin complement(1846907..1847506) Escherichia coli UMN026 7155022 YP_002412551.1 CDS ECUMN_1816 NC_011751.1 1847573 1850971 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J complement(1847573..1850971) Escherichia coli UMN026 7155023 YP_002412552.1 CDS ECUMN_1817 NC_011751.1 1851032 1851679 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I complement(1851032..1851679) Escherichia coli UMN026 7155024 YP_002412553.1 CDS ECUMN_1818 NC_011751.1 1851577 1852329 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber component K of prophage complement(1851577..1852329) Escherichia coli UMN026 7155025 YP_002412554.1 CDS ECUMN_1819 NC_011751.1 1852326 1853024 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L complement(1852326..1853024) Escherichia coli UMN026 7155026 YP_002412555.1 CDS ECUMN_1820 NC_011751.1 1853034 1853363 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M complement(1853034..1853363) Escherichia coli UMN026 7155027 YP_002412556.1 CDS ECUMN_1821 NC_011751.1 1853363 1856458 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail length tape measure protein complement(1853363..1856458) Escherichia coli UMN026 7155028 YP_002412557.1 CDS ECUMN_1822 NC_011751.1 1856400 1856729 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative minor tail protein T of putative prophage complement(1856400..1856729) Escherichia coli UMN026 7155029 YP_002412558.1 CDS ECUMN_1823 NC_011751.1 1856738 1857166 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative minor tail component of putative prophage complement(1856738..1857166) Escherichia coli UMN026 7155030 YP_002412559.1 CDS ECUMN_1824 NC_011751.1 1857185 1857934 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V complement(1857185..1857934) Escherichia coli UMN026 7155031 YP_002412560.1 CDS ECUMN_1825 NC_011751.1 1857940 1858353 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U complement(1857940..1858353) Escherichia coli UMN026 7155032 YP_002412561.1 CDS ECUMN_1826 NC_011751.1 1858338 1858916 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GPZ) of prophage complement(1858338..1858916) Escherichia coli UMN026 7155033 YP_002412562.1 CDS ECUMN_1827 NC_011751.1 1858928 1859203 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1858928..1859203) Escherichia coli UMN026 7155034 YP_002412563.1 CDS ECUMN_1828 NC_011751.1 1859196 1859564 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1859196..1859564) Escherichia coli UMN026 7155035 YP_002412564.1 CDS ECUMN_1829 NC_011751.1 1859606 1861726 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) complement(1859606..1861726) Escherichia coli UMN026 7155036 YP_002412565.1 CDS ECUMN_1830 NC_011751.1 1861578 1863158 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative portal protein complement(1861578..1863158) Escherichia coli UMN026 7155037 YP_002412566.1 CDS ECUMN_1831 NC_011751.1 1863086 1863304 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1863086..1863304) Escherichia coli UMN026 7155038 YP_002412567.1 CDS ECUMN_1832 NC_011751.1 1863295 1865397 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative DNA packaging protein complement(1863295..1865397) Escherichia coli UMN026 7155039 YP_002412568.1 CDS ECUMN_1833 NC_011751.1 1865397 1865891 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1865397..1865891) Escherichia coli UMN026 7155040 YP_002412569.1 CDS ybcW NC_011751.1 1866454 1866660 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1866454..1866660) Escherichia coli UMN026 7155041 YP_002412570.1 CDS ybcV NC_011751.1 1866946 1867371 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1866946..1867371 Escherichia coli UMN026 7158388 YP_002412571.1 CDS gnsB NC_011751.1 1867523 1867696 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21429224; Product type h : extrachromosomal origin; hypothetical protein complement(1867523..1867696) Escherichia coli UMN026 7158387 YP_002412572.1 CDS ECUMN_1838 NC_011751.1 1867868 1868140 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1867868..1868140) Escherichia coli UMN026 7156594 YP_002412573.1 CDS cspI NC_011751.1 1868370 1868582 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881; Product type h : extrachromosomal origin; cold shock protein; Qin prophage complement(1868370..1868582) Escherichia coli UMN026 7155042 YP_002412574.1 CDS ydfP NC_011751.1 1868946 1869443 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1868946..1869443) Escherichia coli UMN026 7156042 YP_002412575.1 CDS ydfQ NC_011751.1 1869440 1869973 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated lysozyme; Qin prophage complement(1869440..1869973) Escherichia coli UMN026 7158651 YP_002412576.1 CDS ydfR NC_011751.1 1869970 1870257 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1869970..1870257) Escherichia coli UMN026 7158653 YP_002412577.1 CDS essQ NC_011751.1 1870286 1870501 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative S lysis protein; Qin prophage complement(1870286..1870501) Escherichia coli UMN026 7158654 YP_002412578.1 CDS cspB NC_011751.1 1871255 1871470 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293754, 94293756, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage complement(1871255..1871470) Escherichia coli UMN026 7156272 YP_002412579.1 CDS cspF NC_011751.1 1871771 1871983 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 8022261, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 1871771..1871983 Escherichia coli UMN026 7156035 YP_002412580.1 CDS ydfT NC_011751.1 1872405 1873157 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative antitermination protein Q; Qin prophage complement(1872405..1873157) Escherichia coli UMN026 7156039 YP_002412581.1 CDS ydfU NC_011751.1 1873171 1874220 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1873171..1874220) Escherichia coli UMN026 7158655 YP_002412582.1 CDS rem NC_011751.1 1874567 1874818 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2990907; Product type h : extrachromosomal origin; hypothetical protein complement(1874567..1874818) Escherichia coli UMN026 7158657 YP_002412583.1 CDS ECUMN_1849 NC_011751.1 1875406 1875609 R hypothetical protein complement(1875406..1875609) Escherichia coli UMN026 7157651 YP_002412584.1 CDS ECUMN_1850 NC_011751.1 1875865 1877652 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1875865..1877652 Escherichia coli UMN026 7155043 YP_002412585.1 CDS ECUMN_1851 NC_011751.1 1877871 1878272 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(1877871..1878272) Escherichia coli UMN026 7155044 YP_002412586.1 CDS ECUMN_1852 NC_011751.1 1878313 1879332 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1878313..1879332) Escherichia coli UMN026 7155045 YP_002412587.1 CDS ECUMN_1853 NC_011751.1 1879259 1879780 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1879259..1879780) Escherichia coli UMN026 7155046 YP_002412588.1 CDS ECUMN_1854 NC_011751.1 1879764 1880018 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA-binding transcriptional regulator DicC complement(1879764..1880018) Escherichia coli UMN026 7155047 YP_002412589.1 CDS dicA NC_011751.1 1880018 1880476 D The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1880018..1880476 Escherichia coli UMN026 7155048 YP_002412590.1 CDS ECUMN_1856 NC_011751.1 1880513 1880824 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1880513..1880824 Escherichia coli UMN026 7156162 YP_002412591.1 CDS ECUMN_1857 NC_011751.1 1880784 1881401 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1880784..1881401 Escherichia coli UMN026 7155049 YP_002412592.1 CDS ECUMN_1859 NC_011751.1 1881783 1882076 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative regulator of cell division encoded by prophage 1881783..1882076 Escherichia coli UMN026 7156165 YP_002412593.1 CDS ydfD NC_011751.1 1882073 1882264 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1882073..1882264 Escherichia coli UMN026 7155051 YP_002412594.1 CDS ECUMN_1861 NC_011751.1 1882358 1884829 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative exonuclease from phage origin 1882358..1884829 Escherichia coli UMN026 7158645 YP_002412595.1 CDS xis NC_011751.1 1884902 1885153 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; prophage excisionase 1884902..1885153 Escherichia coli UMN026 7155052 YP_002412596.1 CDS intQ NC_011751.1 1885173 1886468 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative defective integrase; Qin prophage 1885173..1886468 Escherichia coli UMN026 7158248 YP_002412597.1 CDS ynfP NC_011751.1 1886488 1886598 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1886488..1886598) Escherichia coli UMN026 7156845 YP_002412598.1 CDS rspB NC_011751.1 1886656 1887675 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7545940; Product type pe : putative enzyme; putative dehydrogenase complement(1886656..1887675) Escherichia coli UMN026 7159530 YP_002412599.1 CDS rspA NC_011751.1 1887687 1888901 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : putative enzyme; putative enolase/dehydratase complement(1887687..1888901) Escherichia coli UMN026 7157800 YP_002412600.1 CDS ynfA NC_011751.1 1889107 1889433 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1889107..1889433) Escherichia coli UMN026 7157799 YP_002412601.1 CDS ynfB NC_011751.1 1889568 1889909 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1889568..1889909 Escherichia coli UMN026 7159517 YP_002412602.1 CDS speG NC_011751.1 1889944 1890504 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94357898; Product type e : enzyme; spermidine N1-acetyltransferase 1889944..1890504 Escherichia coli UMN026 7159518 YP_002412603.1 CDS ynfC NC_011751.1 1890507 1891217 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1890507..1891217) Escherichia coli UMN026 7157962 YP_002412604.1 CDS ynfD NC_011751.1 1891325 1891630 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784; hypothetical protein 1891325..1891630 Escherichia coli UMN026 7159519 YP_002412605.1 CDS ynfE NC_011751.1 1891829 1894255 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type e : enzyme; oxidoreductase subunit 1891829..1894255 Escherichia coli UMN026 7159520 YP_002412606.1 CDS ynfF NC_011751.1 1894316 1896739 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type e : enzyme; oxidoreductase subunit 1894316..1896739 Escherichia coli UMN026 7159521 YP_002412607.1 CDS ynfG NC_011751.1 1896750 1897367 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type c : carrier; oxidoreductase, Fe-S subunit 1896750..1897367 Escherichia coli UMN026 7159522 YP_002412608.1 CDS ynfH NC_011751.1 1897369 1898223 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type m : membrane component; oxidoreductase, membrane subunit 1897369..1898223 Escherichia coli UMN026 7159523 YP_002412609.1 CDS dmsD NC_011751.1 1898266 1898880 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1898266..1898880 Escherichia coli UMN026 7159524 YP_002412610.1 CDS clcB NC_011751.1 1899074 1900330 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12384697; Product type pt : putative transporter; putative voltage-gated ClC-type chloride channel ClcB 1899074..1900330 Escherichia coli UMN026 7156182 YP_002412611.1 CDS ynfK NC_011751.1 1900283 1900978 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase complement(1900283..1900978) Escherichia coli UMN026 7155976 YP_002412612.1 CDS dgsA NC_011751.1 1901103 1902323 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10318813, 20490366, 6989798, 99340206, 99395104, 99398866, 7766024; Product type r : regulator; DNA-binding transcriptional repressor complement(1901103..1902323) Escherichia coli UMN026 7159525 YP_002412613.1 CDS ynfL NC_011751.1 1902458 1903351 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(1902458..1903351) Escherichia coli UMN026 7156154 YP_002412614.1 CDS ynfM NC_011751.1 1903458 1904711 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 1903458..1904711 Escherichia coli UMN026 7159526 YP_002412615.1 CDS asr NC_011751.1 1905135 1905443 D required for growth and survival under moderately acid conditions; acid shock protein 1905135..1905443 Escherichia coli UMN026 7159527 YP_002412616.1 CDS ydgD NC_011751.1 1905719 1906540 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported metallopeptidase 1905719..1906540 Escherichia coli UMN026 7155820 YP_002412617.1 CDS mdtI NC_011751.1 1906579 1906908 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1906579..1906908) Escherichia coli UMN026 7158661 YP_002412618.1 CDS ECUMN_1886 NC_011751.1 1907089 1907265 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1907089..1907265) Escherichia coli UMN026 7157086 YP_002412619.1 CDS insH NC_011751.1 1907125 1908141 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage 1907125..1908141 Escherichia coli UMN026 7155053 YP_002412620.1 CDS tqsA NC_011751.1 1908871 1909905 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein 1908871..1909905 Escherichia coli UMN026 7157087 YP_002412621.1 CDS pntB NC_011751.1 1909930 1911318 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1909930..1911318) Escherichia coli UMN026 7158662 YP_002412622.1 CDS pntA NC_011751.1 1911329 1912861 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1911329..1912861) Escherichia coli UMN026 7157482 YP_002412623.1 CDS ydgH NC_011751.1 1913385 1914329 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1913385..1914329 Escherichia coli UMN026 7157481 YP_002412624.1 CDS ydgI NC_011751.1 1914515 1915897 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1311296; Product type pt : putative transporter; putative arginine/ornithine antiporter transporter 1914515..1915897 Escherichia coli UMN026 7158663 YP_002412625.1 CDS folM NC_011751.1 1915934 1916656 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14617668; Product type e : enzyme; short chain dehydrogenase 1915934..1916656 Escherichia coli UMN026 7158664 YP_002412626.1 CDS ydgC NC_011751.1 1916653 1916988 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1916653..1916988) Escherichia coli UMN026 7156429 YP_002412627.1 CDS rstA NC_011751.1 1917108 1917836 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1917108..1917836 Escherichia coli UMN026 7158660 YP_002412628.1 CDS rstB NC_011751.1 1917840 1919141 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93086426, 1495392, 1925016, 2646639; Product type r : regulator; sensor protein RstB 1917840..1919141 Escherichia coli UMN026 7157803 YP_002412629.1 CDS tus NC_011751.1 1919217 1920146 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1919217..1920146 Escherichia coli UMN026 7157804 YP_002412630.1 CDS fumC NC_011751.1 1920143 1921546 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1920143..1921546) Escherichia coli UMN026 7158141 YP_002412631.1 CDS fumA NC_011751.1 1921689 1923335 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193096, 88268900, 92011457, 3005475, 6328431, 9298646; Product type e : enzyme; fumarate hydratase complement(1921689..1923335) Escherichia coli UMN026 7156478 YP_002412632.1 CDS manA NC_011751.1 1923534 1924709 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 6397402; Product type e : enzyme; mannose-6-phosphate isomerase 1923534..1924709 Escherichia coli UMN026 7156476 YP_002412633.1 CDS ydgA NC_011751.1 1924810 1926318 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1924810..1926318 Escherichia coli UMN026 7157054 YP_002412634.1 CDS uidC NC_011751.1 1926363 1927628 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15774881; Product type t : transporter; putative outer membrane porin protein complement(1926363..1927628) Escherichia coli UMN026 7158659 YP_002412635.1 CDS uidB NC_011751.1 1927667 1929040 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3534890; Product type t : transporter; glucuronide transporter complement(1927667..1929040) Escherichia coli UMN026 7158176 YP_002412636.1 CDS uidA NC_011751.1 1929037 1930848 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87041472, 88038341, 2103475, 8125312; Product type e : enzyme; beta-D-glucuronidase complement(1929037..1930848) Escherichia coli UMN026 7158175 YP_002412637.1 CDS uidR NC_011751.1 1931239 1931829 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88038341, 2823062, 3934044, 11115104; Product type r : regulator; DNA-binding transcriptional repressor complement(1931239..1931829) Escherichia coli UMN026 7158174 YP_002412638.1 CDS hdhA NC_011751.1 1932050 1932817 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1932050..1932817) Escherichia coli UMN026 7158177 YP_002412639.1 CDS malI NC_011751.1 1932929 1933957 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1932929..1933957) Escherichia coli UMN026 7156648 YP_002412640.1 CDS malX NC_011751.1 1934132 1935724 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1934132..1935724 Escherichia coli UMN026 7157044 YP_002412641.1 CDS malY NC_011751.1 1935734 1936906 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20164451, 7665481, 91310596; Product type e : enzyme; bifunctional beta-cystathionase, PLP-dependent and regulator of maltose regulon 1935734..1936906 Escherichia coli UMN026 7157051 YP_002412642.1 CDS add NC_011751.1 1937010 1938011 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1937010..1938011 Escherichia coli UMN026 7157052 YP_002412643.1 CDS ydgJ NC_011751.1 1938047 1939087 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(1938047..1939087) Escherichia coli UMN026 7155696 YP_002412644.1 CDS blr NC_011751.1 1939255 1939455 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392465, 10931331; Product type m : membrane component; beta-lactam resistance membrane protein 1939255..1939455 Escherichia coli UMN026 7158665 YP_002412645.1 CDS ydgT NC_011751.1 1939728 1939943 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1939728..1939943 Escherichia coli UMN026 7155888 YP_002412646.1 CDS ydgK NC_011751.1 1940029 1940469 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1940029..1940469 Escherichia coli UMN026 7158668 YP_002412647.1 CDS rsxA NC_011751.1 1940546 1941127 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411911, 10637328, 12773378; Product type pm : putative membrane component; Na(+)-translocating NADH-quinone reductase subunit E 1940546..1941127 Escherichia coli UMN026 7158666 YP_002412648.1 CDS rsxB NC_011751.1 1941127 1941705 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1941127..1941705 Escherichia coli UMN026 7157806 YP_002412649.1 CDS rsxC NC_011751.1 1941698 1943920 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1941698..1943920 Escherichia coli UMN026 7157807 YP_002412650.1 CDS rnfD NC_011751.1 1943921 1944979 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1943921..1944979 Escherichia coli UMN026 7157808 YP_002412651.1 CDS rsxG NC_011751.1 1944983 1945603 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1944983..1945603 Escherichia coli UMN026 7157809 YP_002412652.1 CDS rsxE NC_011751.1 1945607 1946302 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1945607..1946302 Escherichia coli UMN026 7157811 YP_002412653.1 CDS nth NC_011751.1 1946302 1946937 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1946302..1946937 Escherichia coli UMN026 7157810 YP_002412654.1 CDS tppB NC_011751.1 1947548 1949050 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1947548..1949050 Escherichia coli UMN026 7157315 YP_002412655.1 CDS gst NC_011751.1 1949156 1949761 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95096109, 2185038, 9680481; Product type e : enzyme; glutathionine S-transferase 1949156..1949761 Escherichia coli UMN026 7158667 YP_002412656.1 CDS pdxY NC_011751.1 1949805 1950668 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1949805..1950668) Escherichia coli UMN026 7156621 YP_002412657.1 CDS tyrS NC_011751.1 1950727 1952001 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1950727..1952001) Escherichia coli UMN026 7157409 YP_002412658.1 CDS pdxH NC_011751.1 1952130 1952786 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1952130..1952786) Escherichia coli UMN026 7158151 YP_002412659.1 CDS ydhA NC_011751.1 1952845 1953174 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1952845..1953174) Escherichia coli UMN026 7157406 YP_002412660.1 CDS anmK NC_011751.1 1953272 1954381 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1953272..1954381) Escherichia coli UMN026 7158669 YP_002412661.1 CDS slyB NC_011751.1 1954655 1955122 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8544813; Product type lp : lipoprotein; putative outer membrane lipoprotein 1954655..1955122 Escherichia coli UMN026 7155744 YP_002412662.1 CDS slyA NC_011751.1 1955169 1955603 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1955169..1955603) Escherichia coli UMN026 7157937 YP_002412663.1 CDS ydhI NC_011751.1 1955804 1956040 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1955804..1956040 Escherichia coli UMN026 7157936 YP_002412664.1 CDS ydhJ NC_011751.1 1956043 1956900 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12900028; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 1956043..1956900 Escherichia coli UMN026 7158674 YP_002412665.1 CDS ydhK NC_011751.1 1956900 1958912 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1956900..1958912 Escherichia coli UMN026 7158675 YP_002412666.1 CDS sodC NC_011751.1 1958913 1959434 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1958913..1959434) Escherichia coli UMN026 7158676 YP_002412667.1 CDS ydhF NC_011751.1 1959515 1960411 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(1959515..1960411) Escherichia coli UMN026 7157947 YP_002412668.1 CDS ydhM NC_011751.1 1960887 1961402 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1960887..1961402 Escherichia coli UMN026 7158673 YP_002412669.1 CDS nemA NC_011751.1 1961439 1962536 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1961439..1962536 Escherichia coli UMN026 7158677 YP_002412670.1 CDS gloA NC_011751.1 1962617 1963024 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1962617..1963024 Escherichia coli UMN026 7157264 YP_002412671.1 CDS rnt NC_011751.1 1963127 1963774 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1963127..1963774 Escherichia coli UMN026 7156559 YP_002412672.1 CDS lhr NC_011751.1 1963867 1968483 D similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr 1963867..1968483 Escherichia coli UMN026 7157719 YP_002412673.1 CDS ydhD NC_011751.1 1968534 1968881 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15833738, 15840565, 11950925, 12730244; Product type e : enzyme; hypothetical protein complement(1968534..1968881) Escherichia coli UMN026 7156978 YP_002412674.1 CDS ydhO NC_011751.1 1969216 1970043 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported hydrolase 1969216..1970043 Escherichia coli UMN026 7158672 YP_002412675.1 CDS sodB NC_011751.1 1970171 1970752 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1970171..1970752 Escherichia coli UMN026 7158678 YP_002412676.1 CDS ydhP NC_011751.1 1970898 1972067 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative efflux protein; MFS family complement(1970898..1972067) Escherichia coli UMN026 7157946 YP_002412677.1 CDS purR NC_011751.1 1972621 1973646 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1972621..1973646 Escherichia coli UMN026 7158679 YP_002412678.1 CDS ydhB NC_011751.1 1973643 1974575 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404765; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(1973643..1974575) Escherichia coli UMN026 7157583 YP_002412679.1 CDS ydhC NC_011751.1 1974688 1975899 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1974688..1975899 Escherichia coli UMN026 7158670 YP_002412680.1 CDS cfa NC_011751.1 1976190 1977338 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 1976190..1977338 Escherichia coli UMN026 7158671 YP_002412681.1 CDS ribC NC_011751.1 1977378 1978019 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1977378..1978019) Escherichia coli UMN026 7155941 YP_002412682.1 CDS mdtK NC_011751.1 1978234 1979607 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1978234..1979607 Escherichia coli UMN026 7157684 YP_002412683.1 CDS ydhQ NC_011751.1 1979648 1980904 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1979648..1980904) Escherichia coli UMN026 7157088 YP_002412684.1 CDS ydhR NC_011751.1 1981478 1981783 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1981478..1981783 Escherichia coli UMN026 7155572 YP_002412685.1 CDS ydhS NC_011751.1 1981909 1983513 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1981909..1983513 Escherichia coli UMN026 7158681 YP_002412686.1 CDS ydhT NC_011751.1 1983525 1984337 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1983525..1984337) Escherichia coli UMN026 7158682 YP_002412687.1 CDS ydhU NC_011751.1 1984341 1985126 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome b subunit of a reductase complement(1984341..1985126) Escherichia coli UMN026 7158683 YP_002412688.1 CDS ydhX NC_011751.1 1985123 1985791 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S ferridoxin-type subunit of oxidoreductase complement(1985123..1985791) Escherichia coli UMN026 7158684 YP_002412689.1 CDS ydhW NC_011751.1 1985855 1986502 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1985855..1986502) Escherichia coli UMN026 7158687 YP_002412690.1 CDS ydhV NC_011751.1 1986506 1988608 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(1986506..1988608) Escherichia coli UMN026 7158686 YP_002412691.1 CDS ydhY NC_011751.1 1988629 1989255 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; hypothetical protein complement(1988629..1989255) Escherichia coli UMN026 7158685 YP_002412692.1 CDS ydhZ NC_011751.1 1989711 1989920 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1989711..1989920) Escherichia coli UMN026 7158688 YP_002412693.1 CDS pykF NC_011751.1 1990477 1991889 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1990477..1991889 Escherichia coli UMN026 7158689 YP_002412694.1 CDS lpp NC_011751.1 1992200 1992436 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 334727, 338599, 322142, 353292, 391404, 4261992, 4575979, 6765942; Product type lp : lipoprotein; murein lipoprotein 1992200..1992436 Escherichia coli UMN026 7157596 YP_002412695.1 CDS ynhG NC_011751.1 1992500 1993504 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1992500..1993504) Escherichia coli UMN026 7157006 YP_002412696.1 CDS sufE NC_011751.1 1993653 1994069 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1993653..1994069) Escherichia coli UMN026 7159531 YP_002412697.1 CDS sufS NC_011751.1 1994082 1995302 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1994082..1995302) Escherichia coli UMN026 7158006 YP_002412698.1 CDS sufD NC_011751.1 1995299 1996570 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1995299..1996570) Escherichia coli UMN026 7158008 YP_002412699.1 CDS sufC NC_011751.1 1996545 1997291 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase complement(1996545..1997291) Escherichia coli UMN026 7158005 YP_002412700.1 CDS sufB NC_011751.1 1997301 1998788 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1997301..1998788) Escherichia coli UMN026 7158004 YP_002412701.1 CDS sufA NC_011751.1 1998797 1999165 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1998797..1999165) Escherichia coli UMN026 7158003 YP_002412702.1 CDS ydiH NC_011751.1 1999714 1999983 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1999714..1999983) Escherichia coli UMN026 7157837 YP_002412703.1 CDS ydiI NC_011751.1 2000002 2000412 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme; hypothetical protein complement(2000002..2000412) Escherichia coli UMN026 7158695 YP_002412704.1 CDS ydiJ NC_011751.1 2000409 2003465 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11102686; Product type pe : putative enzyme; putative FAD-linked oxidoreductase complement(2000409..2003465) Escherichia coli UMN026 7158696 YP_002412705.1 CDS ydiK NC_011751.1 2003854 2004966 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 2003854..2004966 Escherichia coli UMN026 7158697 YP_002412706.1 CDS ydiL NC_011751.1 2005395 2005751 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2005395..2005751 Escherichia coli UMN026 7157766 YP_002412707.1 CDS ydiM NC_011751.1 2005850 2007064 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2005850..2007064 Escherichia coli UMN026 7158699 YP_002412708.1 CDS ydiN NC_011751.1 2007291 2008556 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 2007291..2008556 Escherichia coli UMN026 7158700 YP_002412709.1 CDS ydiB NC_011751.1 2008568 2009434 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 2008568..2009434 Escherichia coli UMN026 7158701 YP_002412710.1 CDS aroD NC_011751.1 2009465 2010223 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2009465..2010223 Escherichia coli UMN026 7158691 YP_002412711.1 CDS ydiF NC_011751.1 2010368 2011963 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16253988; Product type e : enzyme; short chain acyl-CoA transferase subunit alpha/beta 2010368..2011963 Escherichia coli UMN026 7155786 YP_002412712.1 CDS ydiO NC_011751.1 2011977 2013128 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase 2011977..2013128 Escherichia coli UMN026 7158694 YP_002412713.1 CDS ydiP NC_011751.1 2013171 2014082 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2013171..2014082) Escherichia coli UMN026 7158702 YP_002412714.1 CDS ECUMN_1986 NC_011751.1 2014185 2014361 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2014185..2014361) Escherichia coli UMN026 7158703 YP_002412715.1 CDS ydiQ NC_011751.1 2014398 2015162 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ 2014398..2015162 Escherichia coli UMN026 7155054 YP_002412716.1 CDS ydiR NC_011751.1 2015182 2016120 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 2015182..2016120 Escherichia coli UMN026 7158704 YP_002412717.1 CDS ydiS NC_011751.1 2016176 2017465 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; hypothetical protein 2016176..2017465 Escherichia coli UMN026 7158705 YP_002412718.1 CDS ydiT NC_011751.1 2017462 2017755 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S ferredoxin-type oxidoreductase subunit 2017462..2017755 Escherichia coli UMN026 7158706 YP_002412719.1 CDS ydiD NC_011751.1 2017758 2019458 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 2017758..2019458 Escherichia coli UMN026 7158707 YP_002412720.1 CDS pps NC_011751.1 2019515 2021893 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(2019515..2021893) Escherichia coli UMN026 7158692 YP_002412721.1 CDS ECUMN_1993 NC_011751.1 2021947 2022114 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2021947..2022114) Escherichia coli UMN026 7157511 YP_002412722.1 CDS ydiA NC_011751.1 2022226 2023059 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2022226..2023059 Escherichia coli UMN026 7155055 YP_002412723.1 CDS aroH NC_011751.1 2023216 2024262 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2023216..2024262 Escherichia coli UMN026 7158690 YP_002412724.1 CDS ydiE NC_011751.1 2024394 2024585 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15039350; hypothetical protein 2024394..2024585 Escherichia coli UMN026 7155790 YP_002412725.1 CDS ydiU NC_011751.1 2024589 2026025 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2024589..2026025) Escherichia coli UMN026 7158693 YP_002412726.1 CDS ydiV NC_011751.1 2026088 2026801 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2026088..2026801) Escherichia coli UMN026 7158708 YP_002412727.1 CDS nlpC NC_011751.1 2027048 2027512 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620121; Product type lp : lipoprotein; putative peptidase lipoprotein complement(2027048..2027512) Escherichia coli UMN026 7158709 YP_002412728.1 CDS btuD NC_011751.1 2027590 2028339 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(2027590..2028339) Escherichia coli UMN026 7157287 YP_002412729.1 CDS btuE NC_011751.1 2028339 2028890 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase complement(2028339..2028890) Escherichia coli UMN026 7155896 YP_002412730.1 CDS btuC NC_011751.1 2028953 2029933 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(2028953..2029933) Escherichia coli UMN026 7155897 YP_002412731.1 CDS ihfA NC_011751.1 2030034 2030333 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(2030034..2030333) Escherichia coli UMN026 7155895 YP_002412732.1 CDS pheT NC_011751.1 2030338 2032725 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(2030338..2032725) Escherichia coli UMN026 7156794 YP_002412733.1 CDS pheS NC_011751.1 2032740 2033723 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(2032740..2033723) Escherichia coli UMN026 7157438 YP_002412735.1 CDS rplT NC_011751.1 2034029 2034385 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(2034029..2034385) Escherichia coli UMN026 7157435 YP_002412736.1 CDS rpmI NC_011751.1 2034438 2034635 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93085722, 10094780, 3298224, 3542048, 6325158; Product type s : structure; 50S ribosomal protein L35 complement(2034438..2034635) Escherichia coli UMN026 7157742 YP_002412737.1 CDS thrS NC_011751.1 2035278 2037206 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(2035278..2037206) Escherichia coli UMN026 7156813 YP_002412738.1 CDS ECUMN_2010 NC_011751.1 2037729 2039627 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative ankyrin repeat regulatory protein 2037729..2039627 Escherichia coli UMN026 7158068 YP_002412739.1 CDS ydiY NC_011751.1 2039954 2040712 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2039954..2040712) Escherichia coli UMN026 7155056 YP_002412740.1 CDS pfkB NC_011751.1 2040999 2041928 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 78194149, 88292964, 6235149, 6310120; Product type e : enzyme; 6-phosphofructokinase 2 2040999..2041928 Escherichia coli UMN026 7158710 YP_002412741.1 CDS ydiZ NC_011751.1 2042029 2042319 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2042029..2042319 Escherichia coli UMN026 7157420 YP_002412742.1 CDS yniA NC_011751.1 2042425 2043285 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase/kinase 2042425..2043285 Escherichia coli UMN026 7158711 YP_002412743.1 CDS yniB NC_011751.1 2043326 2043862 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2043326..2043862) Escherichia coli UMN026 7159532 YP_002412744.1 CDS yniC NC_011751.1 2044009 2044677 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2044009..2044677 Escherichia coli UMN026 7159533 YP_002412745.1 CDS ydjM NC_011751.1 2044840 2045430 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10760155; Product type pm : putative membrane component; hypothetical protein 2044840..2045430 Escherichia coli UMN026 7159534 YP_002412746.1 CDS ydjN NC_011751.1 2045563 2046954 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative cation-acid symporter 2045563..2046954 Escherichia coli UMN026 7158721 YP_002412747.1 CDS ydjO NC_011751.1 2046958 2047773 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2046958..2047773) Escherichia coli UMN026 7158722 YP_002412748.1 CDS cedA NC_011751.1 2048050 2048313 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9427399; Product type cp : cell process; cell division modulator complement(2048050..2048313) Escherichia coli UMN026 7158723 YP_002412749.1 CDS katE NC_011751.1 2048496 2050757 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2048496..2050757 Escherichia coli UMN026 7155940 YP_002412750.1 CDS chbG NC_011751.1 2050804 2051553 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20042356, 1987146, 2179047, 8121401, 9405618; hypothetical protein complement(2050804..2051553) Escherichia coli UMN026 7156881 YP_002412751.1 CDS chbF NC_011751.1 2051566 2052918 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042356, 90185127, 9405618; Product type e : enzyme; cryptic phospho-beta-glucosidase complement(2051566..2052918) Escherichia coli UMN026 7155949 YP_002412752.1 CDS chbR NC_011751.1 2053023 2053865 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(2053023..2053865) Escherichia coli UMN026 7155948 YP_002412753.1 CDS chbA NC_011751.1 2053873 2054223 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(2053873..2054223) Escherichia coli UMN026 7155950 YP_002412754.1 CDS chbC NC_011751.1 2054274 2055632 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(2054274..2055632) Escherichia coli UMN026 7155945 YP_002412755.1 CDS chbB NC_011751.1 2055717 2056037 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(2055717..2056037) Escherichia coli UMN026 7155947 YP_002412756.1 CDS osmE NC_011751.1 2056336 2056674 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(2056336..2056674) Escherichia coli UMN026 7155946 YP_002412757.1 CDS nadE NC_011751.1 2056876 2057703 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2056876..2057703 Escherichia coli UMN026 7157365 YP_002412758.1 CDS ydjQ NC_011751.1 2057933 2058820 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2057933..2058820 Escherichia coli UMN026 7157225 YP_002412759.1 CDS ydjR NC_011751.1 2058780 2059355 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21862596; hypothetical protein complement(2058780..2059355) Escherichia coli UMN026 7158724 YP_002412760.1 CDS spy NC_011751.1 2059558 2060043 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein complement(2059558..2060043) Escherichia coli UMN026 7158725 YP_002412761.1 CDS astE NC_011751.1 2060373 2061341 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(2060373..2061341) Escherichia coli UMN026 7157968 YP_002412762.1 CDS astB NC_011751.1 2061334 2062677 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(2061334..2062677) Escherichia coli UMN026 7155826 YP_002412763.1 CDS astD NC_011751.1 2062674 2064152 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(2062674..2064152) Escherichia coli UMN026 7155823 YP_002412764.1 CDS astA NC_011751.1 2064149 2065183 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14675764, 98361920; Product type e : enzyme; arginine succinyltransferase complement(2064149..2065183) Escherichia coli UMN026 7155825 YP_002412765.1 CDS astC NC_011751.1 2065180 2066400 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(2065180..2066400) Escherichia coli UMN026 7155822 YP_002412766.1 CDS xthA NC_011751.1 2066846 2067652 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2066846..2067652 Escherichia coli UMN026 7155824 YP_002412767.1 CDS ydjX NC_011751.1 2067819 2068529 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2067819..2068529 Escherichia coli UMN026 7158251 YP_002412768.1 CDS ydjY NC_011751.1 2068534 2069211 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2068534..2069211 Escherichia coli UMN026 7158726 YP_002412769.1 CDS ydjZ NC_011751.1 2069226 2069933 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2069226..2069933 Escherichia coli UMN026 7158727 YP_002412770.1 CDS ynjA NC_011751.1 2069933 2070481 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2069933..2070481 Escherichia coli UMN026 7158728 YP_002412771.1 CDS ynjB NC_011751.1 2070491 2071657 D Evidence 4 : Homologs of previously reported genes of unknown function; putative ABC transporter solute-binding protein 2070491..2071657 Escherichia coli UMN026 7159535 YP_002412772.1 CDS ynjC NC_011751.1 2071675 2073165 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter membrane protein 2071675..2073165 Escherichia coli UMN026 7159536 YP_002412773.1 CDS ynjD NC_011751.1 2073078 2073815 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sulfate/thiosulfate ABC transporter ATP-binding protein 2073078..2073815 Escherichia coli UMN026 7159537 YP_002412774.1 CDS ynjE NC_011751.1 2073885 2075192 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported thiosulfate sulfur transferase / thiosulfate binding protein 2073885..2075192 Escherichia coli UMN026 7159538 YP_002412775.1 CDS ynjF NC_011751.1 2075201 2075821 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; putative phosphatidyl transferase, inner membrane protein complement(2075201..2075821) Escherichia coli UMN026 7159539 YP_002412776.1 CDS nudG NC_011751.1 2075908 2076315 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101911; Product type e : enzyme; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2075908..2076315 Escherichia coli UMN026 7159540 YP_002412777.1 CDS gdhA NC_011751.1 2076789 2078132 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 2076789..2078132 Escherichia coli UMN026 7157321 YP_002412778.1 CDS topB NC_011751.1 2078209 2080221 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(2078209..2080221) Escherichia coli UMN026 7156526 YP_002412779.1 CDS selD NC_011751.1 2080169 2081212 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(2080169..2081212) Escherichia coli UMN026 7158088 YP_002412780.1 CDS ECUMN_2052 NC_011751.1 2081154 2081303 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2081154..2081303) Escherichia coli UMN026 7157895 YP_002412781.1 CDS ydjA NC_011751.1 2081329 2081880 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(2081329..2081880) Escherichia coli UMN026 7155057 YP_002412782.1 CDS ECUMN_2054 NC_011751.1 2081934 2082098 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2081934..2082098 Escherichia coli UMN026 7158712 YP_002412783.1 CDS sppA NC_011751.1 2082041 2083897 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2082041..2083897 Escherichia coli UMN026 7155058 YP_002412784.1 CDS ansA NC_011751.1 2084063 2085079 D converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2084063..2085079 Escherichia coli UMN026 7157965 YP_002412785.1 CDS pncA NC_011751.1 2085090 2085731 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2085090..2085731 Escherichia coli UMN026 7155745 YP_002412786.1 CDS ydjE NC_011751.1 2085824 2087182 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter complement(2085824..2087182) Escherichia coli UMN026 7157478 YP_002412787.1 CDS ydjF NC_011751.1 2087300 2088058 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2087300..2088058) Escherichia coli UMN026 7158713 YP_002412788.1 CDS ydjG NC_011751.1 2088195 2089175 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(2088195..2089175) Escherichia coli UMN026 7158714 YP_002412789.1 CDS ydjH NC_011751.1 2089185 2090132 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar kinase complement(2089185..2090132) Escherichia coli UMN026 7158715 YP_002412790.1 CDS ydjI NC_011751.1 2090137 2090973 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldolase complement(2090137..2090973) Escherichia coli UMN026 7158716 YP_002412791.1 CDS ydjJ NC_011751.1 2090994 2092037 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12897001; Product type pe : putative enzyme; putative iditol dehydrogenase complement(2090994..2092037) Escherichia coli UMN026 7158717 YP_002412792.1 CDS ydjK NC_011751.1 2092054 2093433 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter complement(2092054..2093433) Escherichia coli UMN026 7158718 YP_002412793.1 CDS ydjL NC_011751.1 2093460 2094536 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(2093460..2094536) Escherichia coli UMN026 7158719 YP_002412794.1 CDS yeaC NC_011751.1 2094906 2095178 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2094906..2095178) Escherichia coli UMN026 7158720 YP_002412795.1 CDS msrB NC_011751.1 2095220 2095633 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(2095220..2095633) Escherichia coli UMN026 7158730 YP_002412796.1 CDS gapA NC_011751.1 2095975 2096970 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 775311, 94131963, 98361923, 1862091, 2124629, 2990926, 7896119, 8636984, 9298646; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase A 2095975..2096970 Escherichia coli UMN026 7157188 YP_002412797.1 CDS yeaD NC_011751.1 2097054 2097938 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2097054..2097938 Escherichia coli UMN026 7156503 YP_002412798.1 CDS yeaE NC_011751.1 2097989 2098843 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(2097989..2098843) Escherichia coli UMN026 7158731 YP_002412799.1 CDS mipA NC_011751.1 2098933 2099679 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10037771, 20267815; Product type f : factor; scaffolding protein for murein synthesizing machinery complement(2098933..2099679) Escherichia coli UMN026 7158732 YP_002412800.1 CDS yeaG NC_011751.1 2100115 2102049 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2100115..2102049 Escherichia coli UMN026 7157137 YP_002412801.1 CDS yeaH NC_011751.1 2102162 2103445 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2102162..2103445 Escherichia coli UMN026 7158733 YP_002412802.1 CDS yeaI NC_011751.1 2103592 2105067 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 2103592..2105067 Escherichia coli UMN026 7158734 YP_002412803.1 CDS yeaJ NC_011751.1 2105248 2106738 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 2105248..2106738 Escherichia coli UMN026 7158735 YP_002412804.1 CDS yeaK NC_011751.1 2106781 2107284 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2106781..2107284 Escherichia coli UMN026 7158736 YP_002412805.1 CDS ECUMN_2077 NC_011751.1 2107285 2107437 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2107285..2107437) Escherichia coli UMN026 7158737 YP_002412806.1 CDS yeaL NC_011751.1 2107559 2108005 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2107559..2108005 Escherichia coli UMN026 7155059 YP_002412807.1 CDS yeaM NC_011751.1 2107962 2108783 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2107962..2108783) Escherichia coli UMN026 7158738 YP_002412808.1 CDS yeaN NC_011751.1 2108880 2110061 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2108880..2110061 Escherichia coli UMN026 7158739 YP_002412809.1 CDS yeaO NC_011751.1 2110116 2110463 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2110116..2110463 Escherichia coli UMN026 7158740 YP_002412810.1 CDS yoaF NC_011751.1 2110485 2110739 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2110485..2110739) Escherichia coli UMN026 7158741 YP_002412811.1 CDS yeaP NC_011751.1 2110922 2111947 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 2110922..2111947 Escherichia coli UMN026 7159545 YP_002412812.1 CDS yeaQ NC_011751.1 2112214 2112462 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2112214..2112462) Escherichia coli UMN026 7158742 YP_002412813.1 CDS yoaG NC_011751.1 2112610 2112792 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2112610..2112792) Escherichia coli UMN026 7158743 YP_002412814.1 CDS yeaR NC_011751.1 2112796 2113155 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2112796..2113155) Escherichia coli UMN026 7159546 YP_002412815.1 CDS yeaS NC_011751.1 2113328 2113966 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; leucine export protein LeuE complement(2113328..2113966) Escherichia coli UMN026 7158744 YP_002412816.1 CDS yeaT NC_011751.1 2114093 2115016 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2114093..2115016) Escherichia coli UMN026 7158745 YP_002412817.1 CDS yeaU NC_011751.1 2115119 2116204 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative tartrate dehydrogenase 2115119..2116204 Escherichia coli UMN026 7158746 YP_002412818.1 CDS ECUMN_2092 NC_011751.1 2116455 2116769 D Evidence 7 : Gene remnant; Product type pt : putative transporter; putative quarternary ammonium transport protein (fragment) 2116455..2116769 Escherichia coli UMN026 7158747 YP_002412819.1 CDS yeaW NC_011751.1 2118097 2119221 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 2Fe-2S cluster-containing dioxygenase subunit 2118097..2119221 Escherichia coli UMN026 7158748 YP_002412820.1 CDS yeaX NC_011751.1 2119277 2120242 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dioxygenase subunit 2119277..2120242 Escherichia coli UMN026 7158749 YP_002412821.1 CDS rnd NC_011751.1 2120296 2121423 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88289400, 89053950, 93015723, 8107670; Product type e : enzyme; ribonuclease D complement(2120296..2121423) Escherichia coli UMN026 7158750 YP_002412822.1 CDS fadD NC_011751.1 2121493 2123178 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(2121493..2123178) Escherichia coli UMN026 7157710 YP_002412823.1 CDS yeaY NC_011751.1 2123383 2123964 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type lp : lipoprotein; putative outer membrane-associated lipoprotein complement(2123383..2123964) Escherichia coli UMN026 7156304 YP_002412824.1 CDS yeaZ NC_011751.1 2124003 2124698 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase complement(2124003..2124698) Escherichia coli UMN026 7158751 YP_002412825.1 CDS yoaA NC_011751.1 2124756 2126666 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-dependent helicase complement(2124756..2126666) Escherichia coli UMN026 7158752 YP_002412826.1 CDS yoaB NC_011751.1 2126798 2127142 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2126798..2127142 Escherichia coli UMN026 7159541 YP_002412827.1 CDS yoaC NC_011751.1 2127504 2127863 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2127504..2127863 Escherichia coli UMN026 7159542 YP_002412828.1 CDS yoaH NC_011751.1 2127983 2128162 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2127983..2128162) Escherichia coli UMN026 7159543 YP_002412829.1 CDS pabB NC_011751.1 2128236 2129597 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88025006, 91067712, 91302313, 96011382, 6330050, 7896119; Product type e : enzyme; aminodeoxychorismate synthase, subunit I 2128236..2129597 Escherichia coli UMN026 7159547 YP_002412830.1 CDS yeaB NC_011751.1 2129601 2130179 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme; hypothetical protein 2129601..2130179 Escherichia coli UMN026 7157374 YP_002412831.1 CDS sdaA NC_011751.1 2130363 2131727 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155761, 89359152, 91056090, 93170282; Product type e : enzyme; L-serine deaminase I 2130363..2131727 Escherichia coli UMN026 7158729 YP_002412832.1 CDS adrB NC_011751.1 2131858 2133456 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16513732; Product type pe : putative enzyme; putative cyclic di-GMP phosphodiesterase 2131858..2133456 Escherichia coli UMN026 7157877 YP_002412833.1 CDS yoaE NC_011751.1 2133460 2135016 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein complement(2133460..2135016) Escherichia coli UMN026 7155704 YP_002412834.1 CDS manX NC_011751.1 2135479 2136450 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165962, 90036983, 8131846, 8676384, 9074635, 9298646; Product type t : transporter; PTS system mannose-specific transporter subunit IIAB 2135479..2136450 Escherichia coli UMN026 7159544 YP_002412835.1 CDS manY NC_011751.1 2136513 2137313 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 87165962, 90036983, 94086520, 97128775, 7811395, 8774730; Product type t : transporter; mannose-specific enzyme IIC component of PTS 2136513..2137313 Escherichia coli UMN026 7157056 YP_002412836.1 CDS manZ NC_011751.1 2137317 2138177 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2137317..2138177 Escherichia coli UMN026 7157057 YP_002412837.1 CDS yobD NC_011751.1 2138232 2138690 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2138232..2138690 Escherichia coli UMN026 7157058 YP_002412838.1 CDS ECUMN_2113 NC_011751.1 2138877 2139122 D Evidence 6 : Doubtful CDS; hypothetical protein 2138877..2139122 Escherichia coli UMN026 7159550 YP_002412839.1 CDS yebN NC_011751.1 2139119 2139685 D membrane protein YebN; hypothetical protein 2139119..2139685 Escherichia coli UMN026 7155061 YP_002412840.1 CDS rrmA NC_011751.1 2139682 2140491 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A complement(2139682..2140491) Escherichia coli UMN026 7158760 YP_002412841.1 CDS cspC NC_011751.1 2140657 2140866 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 21101802, 94293754, 12071744, 7984109, 8022261, 9298646, 9868784, 9921691; Product type f : factor; cold shock-like protein CspC complement(2140657..2140866) Escherichia coli UMN026 7157789 YP_002412842.1 CDS yobF NC_011751.1 2140879 2141022 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2140879..2141022) Escherichia coli UMN026 7156036 YP_002412843.1 CDS yebO NC_011751.1 2141692 2141979 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2141692..2141979) Escherichia coli UMN026 7159551 YP_002412844.1 CDS yobG NC_011751.1 2142054 2142197 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2142054..2142197) Escherichia coli UMN026 7158761 YP_002412845.1 CDS kdgR NC_011751.1 2142738 2143529 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659677, 4359651; Product type r : regulator; DNA-binding transcriptional repressor KdgR complement(2142738..2143529) Escherichia coli UMN026 7159553 YP_002412846.1 CDS yebQ NC_011751.1 2143706 2145079 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2143706..2145079 Escherichia coli UMN026 7156888 YP_002412847.1 CDS htpX NC_011751.1 2145125 2146006 R putative metalloprotease; heat shock protein HtpX complement(2145125..2146006) Escherichia coli UMN026 7158762 YP_002412848.1 CDS prc NC_011751.1 2146198 2148246 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(2146198..2148246) Escherichia coli UMN026 7156727 YP_002412849.1 CDS proQ NC_011751.1 2148266 2148964 R affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector complement(2148266..2148964) Escherichia coli UMN026 7157516 YP_002412850.1 CDS yebR NC_011751.1 2149061 2149612 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2149061..2149612) Escherichia coli UMN026 7157534 YP_002412851.1 CDS yebS NC_011751.1 2149688 2150971 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2149688..2150971 Escherichia coli UMN026 7158763 YP_002412852.1 CDS yebT NC_011751.1 2150940 2153573 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2150940..2153573 Escherichia coli UMN026 7158764 YP_002412853.1 CDS yebU NC_011751.1 2153653 2155092 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2153653..2155092 Escherichia coli UMN026 7158765 YP_002412854.1 CDS yebV NC_011751.1 2155210 2155446 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2155210..2155446 Escherichia coli UMN026 7158766 YP_002412855.1 CDS yebW NC_011751.1 2155467 2155742 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2155467..2155742 Escherichia coli UMN026 7158767 YP_002412856.1 CDS pphA NC_011751.1 2155743 2156399 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(2155743..2156399) Escherichia coli UMN026 7158768 YP_002412857.1 CDS yebY NC_011751.1 2156795 2157136 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2156795..2157136) Escherichia coli UMN026 7155062 YP_002412858.1 CDS yebZ NC_011751.1 2157149 2158021 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2157149..2158021) Escherichia coli UMN026 7158769 YP_002412859.1 CDS yobA NC_011751.1 2158025 2158399 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2158025..2158399) Escherichia coli UMN026 7158770 YP_002412860.1 CDS holE NC_011751.1 2158538 2158768 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15090519, 92147649, 92156151, 94131961, 1575709, 8341603, 8505306; Product type e : enzyme; DNA polymerase III subunit theta 2158538..2158768 Escherichia coli UMN026 7159548 YP_002412861.1 CDS yobB NC_011751.1 2158870 2159526 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2158870..2159526 Escherichia coli UMN026 7156700 YP_002412862.1 CDS exoX NC_011751.1 2159550 2160212 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2159550..2160212 Escherichia coli UMN026 7159549 YP_002412863.1 CDS ptrB NC_011751.1 2160209 2162269 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(2160209..2162269) Escherichia coli UMN026 7156290 YP_002412864.1 CDS ECUMN_2141 NC_011751.1 2162426 2162851 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS200, part of IS605 with following ORF complement(2162426..2162851) Escherichia coli UMN026 7157564 YP_002412865.1 CDS ECUMN_2142 NC_011751.1 2162908 2164077 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, part of IS605 with preceding ORF 2162908..2164077 Escherichia coli UMN026 7155063 YP_002412866.1 CDS yebE NC_011751.1 2164241 2164900 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2164241..2164900) Escherichia coli UMN026 7155064 YP_002412867.1 CDS yebF NC_011751.1 2165227 2165595 R secreted protein; unknown function; hypothetical protein complement(2165227..2165595) Escherichia coli UMN026 7158756 YP_002412868.1 CDS yebG NC_011751.1 2165650 2165940 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9368369, 99403401; Product type cp : cell process; DNA damage-inducible protein YebG complement(2165650..2165940) Escherichia coli UMN026 7158757 YP_002412869.1 CDS purT NC_011751.1 2166074 2167252 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2166074..2167252 Escherichia coli UMN026 7158758 YP_002412870.1 CDS eda NC_011751.1 2167307 2167948 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(2167307..2167948) Escherichia coli UMN026 7157584 YP_002412871.1 CDS edd NC_011751.1 2167985 2169796 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2167985..2169796) Escherichia coli UMN026 7156226 YP_002412872.1 CDS zwf NC_011751.1 2170031 2171506 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2170031..2171506) Escherichia coli UMN026 7156227 YP_002412873.1 CDS yebK NC_011751.1 2171844 2172713 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2171844..2172713 Escherichia coli UMN026 7159697 YP_002412874.1 CDS pykA NC_011751.1 2172841 2174283 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2172841..2174283 Escherichia coli UMN026 7158759 YP_002412875.1 CDS lpxM NC_011751.1 2174415 2175386 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(2174415..2175386) Escherichia coli UMN026 7157595 YP_002412876.1 CDS yebA NC_011751.1 2175506 2176828 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1732206; Product type pe : putative enzyme; hypothetical protein complement(2175506..2176828) Escherichia coli UMN026 7157016 YP_002412877.1 CDS znuA NC_011751.1 2176844 2177776 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component complement(2176844..2177776) Escherichia coli UMN026 7158753 YP_002412878.1 CDS znuC NC_011751.1 2177855 2178610 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2177855..2178610 Escherichia coli UMN026 7159689 YP_002412879.1 CDS znuB NC_011751.1 2178607 2179392 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 2178607..2179392 Escherichia coli UMN026 7159691 YP_002412880.1 CDS ruvB NC_011751.1 2179544 2180554 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2179544..2180554) Escherichia coli UMN026 7159690 YP_002412881.1 CDS ruvA NC_011751.1 2180563 2181174 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2180563..2181174) Escherichia coli UMN026 7157831 YP_002412882.1 CDS yebB NC_011751.1 2181449 2182051 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2181449..2182051 Escherichia coli UMN026 7157830 YP_002412883.1 CDS ruvC NC_011751.1 2182053 2182574 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2182053..2182574) Escherichia coli UMN026 7158754 YP_002412884.1 CDS yebC NC_011751.1 2182609 2183349 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2182609..2183349) Escherichia coli UMN026 7157832 YP_002412885.1 CDS ntpA NC_011751.1 2183378 2183821 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2183378..2183821) Escherichia coli UMN026 7158755 YP_002412886.1 CDS aspS NC_011751.1 2183823 2185595 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2183823..2185595) Escherichia coli UMN026 7157316 YP_002412887.1 CDS yecD NC_011751.1 2185905 2186471 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2185905..2186471 Escherichia coli UMN026 7155819 YP_002412888.1 CDS yecE NC_011751.1 2186468 2187286 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2129559, 7984428; hypothetical protein 2186468..2187286 Escherichia coli UMN026 7158773 YP_002412889.1 CDS yecN NC_011751.1 2187339 2187734 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2187339..2187734 Escherichia coli UMN026 7158774 YP_002412890.1 CDS yecO NC_011751.1 2187775 2188518 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11746687; Product type e : enzyme; AdoMet-dependent methyltransferase 2187775..2188518 Escherichia coli UMN026 7158781 YP_002412891.1 CDS yecP NC_011751.1 2188515 2189486 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2188515..2189486 Escherichia coli UMN026 7158782 YP_002412892.1 CDS torZ NC_011751.1 2189521 2191950 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97077292, 11004177; Product type e : enzyme; trimethylamine N-oxide reductase system III, catalytic subunit complement(2189521..2191950) Escherichia coli UMN026 7158783 YP_002412893.1 CDS torY NC_011751.1 2191975 2193075 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461225, 8919859; Product type c : carrier; TMAO reductase III (TorYZ), cytochrome c-type subunit complement(2191975..2193075) Escherichia coli UMN026 7158096 YP_002412894.1 CDS cutC NC_011751.1 2193461 2194207 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95362641, 7635807; Product type t : transporter; copper homeostasis protein CutC complement(2193461..2194207) Escherichia coli UMN026 7158095 YP_002412895.1 CDS yecM NC_011751.1 2194221 2194787 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12660999; Product type pe : putative enzyme; hypothetical protein complement(2194221..2194787) Escherichia coli UMN026 7156057 YP_002412896.1 CDS argS NC_011751.1 2195003 2196736 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2195003..2196736 Escherichia coli UMN026 7158780 YP_002412897.1 CDS flhE NC_011751.1 2196789 2197181 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8002587, 1482109, 89181349; hypothetical protein complement(2196789..2197181) Escherichia coli UMN026 7155780 YP_002412898.1 CDS flhA NC_011751.1 2197181 2199259 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2197181..2199259) Escherichia coli UMN026 7156395 YP_002412899.1 CDS flhB NC_011751.1 2199252 2200400 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2199252..2200400) Escherichia coli UMN026 7156391 YP_002412900.1 CDS cheZ NC_011751.1 2200602 2201246 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(2200602..2201246) Escherichia coli UMN026 7156392 YP_002412901.1 CDS cheY NC_011751.1 2201257 2201646 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(2201257..2201646) Escherichia coli UMN026 7155956 YP_002412902.1 CDS cheB NC_011751.1 2201661 2202710 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2201661..2202710) Escherichia coli UMN026 7155955 YP_002412903.1 CDS cheR NC_011751.1 2202713 2203573 R methylates the MCP; chemotaxis methyltransferase CheR complement(2202713..2203573) Escherichia coli UMN026 7155952 YP_002412904.1 CDS tap NC_011751.1 2203592 2205193 R mediates taxis toward dipeptides; methyl-accepting protein IV complement(2203592..2205193) Escherichia coli UMN026 7155953 YP_002412905.1 CDS tar NC_011751.1 2205239 2206900 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90094243, 92165727, 6305515, 9315712; Product type r : regulator; methyl-accepting chemotaxis protein II complement(2205239..2206900) Escherichia coli UMN026 7158022 YP_002412906.1 CDS cheW NC_011751.1 2207045 2207548 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91126073, 91296802, 91317710, 2002011, 3510184; Product type r : regulator; purine-binding chemotaxis protein complement(2207045..2207548) Escherichia coli UMN026 7155905 YP_002412907.1 CDS cheA NC_011751.1 2207569 2209533 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(2207569..2209533) Escherichia coli UMN026 7155954 YP_002412908.1 CDS motB NC_011751.1 2209538 2210464 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(2209538..2210464) Escherichia coli UMN026 7155951 YP_002412909.1 CDS motA NC_011751.1 2210461 2211348 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2210461..2211348) Escherichia coli UMN026 7157163 YP_002412910.1 CDS flhC NC_011751.1 2211475 2212053 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(2211475..2212053) Escherichia coli UMN026 7157162 YP_002412911.1 CDS flhD NC_011751.1 2212056 2212415 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2212056..2212415) Escherichia coli UMN026 7156393 YP_002412912.1 CDS yecG NC_011751.1 2213187 2213615 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2213187..2213615 Escherichia coli UMN026 7156394 YP_002412913.1 CDS otsA NC_011751.1 2213622 2215046 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 92121128, 93302496, 8045430; Product type e : enzyme; trehalose-6-phosphate synthase complement(2213622..2215046) Escherichia coli UMN026 7158776 YP_002412914.1 CDS otsB NC_011751.1 2215021 2215821 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2215021..2215821) Escherichia coli UMN026 7157367 YP_002412915.1 CDS araH NC_011751.1 2215988 2216977 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease protein complement(2215988..2216977) Escherichia coli UMN026 7157368 YP_002412916.1 CDS araG NC_011751.1 2216989 2218503 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2216989..2218503) Escherichia coli UMN026 7155764 YP_002412917.1 CDS araF NC_011751.1 2218573 2219562 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89255061, 90375534, 2445996, 326784, 326785, 6885805, 7031057, 9298646; Product type t : transporter; L-arabinose ABC transporter periplasmic-binding protein complement(2218573..2219562) Escherichia coli UMN026 7155763 YP_002412918.1 CDS yecI NC_011751.1 2220359 2220862 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative ferritin-like protein 2220359..2220862 Escherichia coli UMN026 7155762 YP_002412919.1 CDS yecJ NC_011751.1 2220942 2221193 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2220942..2221193) Escherichia coli UMN026 7158778 YP_002412920.1 CDS ECUMN_2198 NC_011751.1 2221305 2221451 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2221305..2221451 Escherichia coli UMN026 7156871 YP_002412921.1 CDS yecR NC_011751.1 2221657 2221980 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2221657..2221980 Escherichia coli UMN026 7155065 YP_002412922.1 CDS ftn NC_011751.1 2222151 2222648 D cytoplasmic iron storage protein; ferritin 2222151..2222648 Escherichia coli UMN026 7158784 YP_002412923.1 CDS yecH NC_011751.1 2222686 2222925 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2222686..2222925) Escherichia coli UMN026 7156455 YP_002412924.1 CDS tyrP NC_011751.1 2223116 2224327 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89008121, 2022620; Product type t : transporter; tyrosine transporter 2223116..2224327 Escherichia coli UMN026 7158777 YP_002412925.1 CDS yecA NC_011751.1 2224389 2225054 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2224389..2225054) Escherichia coli UMN026 7158149 YP_002412926.1 CDS pgsA NC_011751.1 2225704 2226252 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 381294, 7007311, 94253011, 1323047, 3003065, 8917447; Product type e : enzyme; phosphatidylglycerophosphate synthetase complement(2225704..2226252) Escherichia coli UMN026 7155636 YP_002412927.1 CDS uvrC NC_011751.1 2226309 2228141 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2226309..2228141) Escherichia coli UMN026 7157432 YP_002412928.1 CDS uvrY NC_011751.1 2228138 2228794 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2228138..2228794) Escherichia coli UMN026 7158200 YP_002412929.1 CDS yecF NC_011751.1 2229253 2229477 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3515318, 7567469; hypothetical protein 2229253..2229477 Escherichia coli UMN026 7158202 YP_002412930.1 CDS sdiA NC_011751.1 2229545 2230267 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2229545..2230267) Escherichia coli UMN026 7158775 YP_002412931.1 CDS yecC NC_011751.1 2230497 2231249 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino-acid ABC transporter ATP-binding protein YecC complement(2230497..2231249) Escherichia coli UMN026 7157884 YP_002412932.1 CDS yecS NC_011751.1 2231246 2231914 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease complement(2231246..2231914) Escherichia coli UMN026 7158772 YP_002412933.1 CDS yedO NC_011751.1 2231929 2232915 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2231929..2232915) Escherichia coli UMN026 7158785 YP_002412934.1 CDS fliY NC_011751.1 2233020 2233820 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125225, 8450713, 8774726, 9298646, 9740056; Product type t : transporter; cystine transporter subunit complement(2233020..2233820) Escherichia coli UMN026 7158794 YP_002412935.1 CDS fliZ NC_011751.1 2233908 2234459 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2233908..2234459) Escherichia coli UMN026 7156414 YP_002412936.1 CDS fliA NC_011751.1 2234505 2235224 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2234505..2235224) Escherichia coli UMN026 7156415 YP_002412937.1 CDS ECUMN_2215 NC_011751.1 2235544 2237208 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2235544..2237208) Escherichia coli UMN026 7156396 YP_002412938.1 CDS fliD NC_011751.1 2237474 2238880 D involved in flagellin assembly; flagellar capping protein 2237474..2238880 Escherichia coli UMN026 7155066 YP_002412939.1 CDS fliS NC_011751.1 2238905 2239315 D flagellin specific chaperone; flagellar protein FliS 2238905..2239315 Escherichia coli UMN026 7156397 YP_002412940.1 CDS fliT NC_011751.1 2239315 2239680 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2239315..2239680 Escherichia coli UMN026 7156412 YP_002412941.1 CDS amyA NC_011751.1 2239758 2241245 D converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2239758..2241245 Escherichia coli UMN026 7156413 YP_002412942.1 CDS yedD NC_011751.1 2241279 2241692 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2241279..2241692) Escherichia coli UMN026 7155743 YP_002412943.1 CDS yedE NC_011751.1 2241879 2243084 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; putative inner membrane protein 2241879..2243084 Escherichia coli UMN026 7158787 YP_002412944.1 CDS yedF NC_011751.1 2243081 2243314 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2243081..2243314 Escherichia coli UMN026 7158788 YP_002412945.1 CDS yedK NC_011751.1 2243421 2244089 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2243421..2244089 Escherichia coli UMN026 7158789 YP_002412946.1 CDS yedL NC_011751.1 2244200 2244595 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 2244200..2244595 Escherichia coli UMN026 7158792 YP_002412947.1 CDS ECUMN_2226 NC_011751.1 2244818 2245033 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2244818..2245033) Escherichia coli UMN026 7158793 YP_002412948.1 CDS ECUMN_2227 NC_011751.1 2245129 2245932 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2245129..2245932) Escherichia coli UMN026 7155067 YP_002412949.1 CDS fliE NC_011751.1 2246292 2246606 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2246292..2246606) Escherichia coli UMN026 7155068 YP_002412950.1 CDS fliF NC_011751.1 2246821 2248479 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2246821..2248479 Escherichia coli UMN026 7156398 YP_002412951.1 CDS fliG NC_011751.1 2248472 2249467 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2248472..2249467 Escherichia coli UMN026 7156399 YP_002412952.1 CDS fliH NC_011751.1 2249460 2250146 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2249460..2250146 Escherichia coli UMN026 7156400 YP_002412953.1 CDS fliI NC_011751.1 2250146 2251519 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2250146..2251519 Escherichia coli UMN026 7156401 YP_002412954.1 CDS fliJ NC_011751.1 2251538 2251981 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2251538..2251981 Escherichia coli UMN026 7156402 YP_002412955.1 CDS fliK NC_011751.1 2251978 2253105 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1482109, 8631687; Product type s : structure; flagellar hook-length control protein 2251978..2253105 Escherichia coli UMN026 7156403 YP_002412956.1 CDS fliL NC_011751.1 2253210 2253674 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2253210..2253674 Escherichia coli UMN026 7156404 YP_002412957.1 CDS fliM NC_011751.1 2253679 2254683 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2253679..2254683 Escherichia coli UMN026 7156405 YP_002412958.1 CDS fliN NC_011751.1 2254680 2255093 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2254680..2255093 Escherichia coli UMN026 7156406 YP_002412959.1 CDS fliO NC_011751.1 2255096 2255461 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2255096..2255461 Escherichia coli UMN026 7156407 YP_002412960.1 CDS fliP NC_011751.1 2255461 2256198 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2255461..2256198 Escherichia coli UMN026 7156408 YP_002412961.1 CDS fliQ NC_011751.1 2256208 2256477 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2256208..2256477 Escherichia coli UMN026 7156409 YP_002412962.1 CDS fliR NC_011751.1 2256486 2257271 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2256486..2257271 Escherichia coli UMN026 7156410 YP_002412963.1 CDS rcsA NC_011751.1 2257561 2258184 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14514676, 14766922, 20167175, 90130299, 91154130, 92048476, 9882673, 7534408; Product type r : regulator; DNA-binding transcriptional activator, co-regulator with RcsB 2257561..2258184 Escherichia coli UMN026 7156411 YP_002412964.1 CDS dsrB NC_011751.1 2258228 2258416 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96324407, 7534408; hypothetical protein complement(2258228..2258416) Escherichia coli UMN026 7157628 YP_002412965.1 CDS yodD NC_011751.1 2258579 2258806 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2258579..2258806 Escherichia coli UMN026 7156210 YP_002412966.1 CDS yedP NC_011751.1 2259104 2259919 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2259104..2259919 Escherichia coli UMN026 7156208 YP_002412967.1 CDS yedQ NC_011751.1 2259916 2261610 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16530465; Product type pe : putative enzyme; putative diguanylate cyclase complement(2259916..2261610) Escherichia coli UMN026 7158795 YP_002412968.1 CDS ECUMN_2248 NC_011751.1 2261531 2261719 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2261531..2261719) Escherichia coli UMN026 7158796 YP_002412969.1 CDS yodC NC_011751.1 2261781 2261963 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2261781..2261963) Escherichia coli UMN026 7155069 YP_002412970.1 CDS yedI NC_011751.1 2262042 2262959 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2262042..2262959) Escherichia coli UMN026 7159555 YP_002412971.1 CDS yedA NC_011751.1 2263132 2264052 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2263132..2264052 Escherichia coli UMN026 7158790 YP_002412972.1 CDS vsr NC_011751.1 2264041 2264511 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330522, 92049708, 94049122, 10360178, 10612397, 10871403, 2527357; Product type e : enzyme; DNA mismatch endonuclease of very short patch repair complement(2264041..2264511) Escherichia coli UMN026 7158786 YP_002412973.1 CDS dcm NC_011751.1 2264492 2265910 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90280700, 91285397, 93367813, 2198248, 2527357; Product type e : enzyme; DNA cytosine methylase complement(2264492..2265910) Escherichia coli UMN026 7158212 YP_002412974.1 CDS yedJ NC_011751.1 2265977 2266672 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme; hypothetical protein complement(2265977..2266672) Escherichia coli UMN026 7156114 YP_002412975.1 CDS yedR NC_011751.1 2266712 2267077 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2266712..2267077) Escherichia coli UMN026 7158791 YP_002412976.1 CDS ECUMN_2256 NC_011751.1 2267613 2268821 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9642192; Product type m : membrane component; porin OmpN 2267613..2268821 Escherichia coli UMN026 7157795 YP_002412977.1 CDS hchA NC_011751.1 2269413 2270264 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2269413..2270264 Escherichia coli UMN026 7155070 YP_002412978.1 CDS yedV NC_011751.1 2270372 2271730 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865; Product type rc : receptor; sensory kinase in two-component regulatory system with YedW complement(2270372..2271730) Escherichia coli UMN026 7156640 YP_002412979.1 CDS yedW NC_011751.1 2271730 2272401 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2271730..2272401) Escherichia coli UMN026 7158798 YP_002412980.1 CDS yedX NC_011751.1 2272534 2272947 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2272534..2272947 Escherichia coli UMN026 7158799 YP_002412981.1 CDS yedY NC_011751.1 2273056 2274060 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 2273056..2274060 Escherichia coli UMN026 7158800 YP_002412982.1 CDS yedZ NC_011751.1 2274061 2274696 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 2274061..2274696 Escherichia coli UMN026 7158801 YP_002412983.1 CDS yodA NC_011751.1 2274953 2275603 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12077457, 12480884, 12909634, 9579078; hypothetical protein 2274953..2275603 Escherichia coli UMN026 7158802 YP_002412984.1 CDS yeeI NC_011751.1 2276457 2277254 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2276457..2277254 Escherichia coli UMN026 7155635 YP_002412985.1 CDS int NC_011751.1 2277592 2278854 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; integrase 2277592..2278854 Escherichia coli UMN026 7155573 YP_002412986.1 CDS irp NC_011751.1 2279048 2280352 R catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 complement(2279048..2280352) Escherichia coli UMN026 7156842 YP_002412987.1 CDS irp NC_011751.1 2280380 2281783 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; yersiniabactin-iron transporter permease YbtX complement(2280380..2281783) Escherichia coli UMN026 7156847 YP_002412988.1 CDS irp NC_011751.1 2281653 2283482 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter; yersiniabactin-iron ABC transporter permease and ATP-binding protein YbtQ complement(2281653..2283482) Escherichia coli UMN026 7156848 YP_002412989.1 CDS irp NC_011751.1 2283442 2285244 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter; yersiniabactin-iron ABC transporter permease and ATP-binding protein YbtP complement(2283442..2285244) Escherichia coli UMN026 7156849 YP_002412990.1 CDS ybtA NC_011751.1 2285411 2286370 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8930916; Product type r : regulator; AraC family transcriptional regulator 2285411..2286370 Escherichia coli UMN026 7156850 YP_002412991.1 CDS irp NC_011751.1 2286543 2292668 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 8366034, 11927258, 9709002; Product type e : enzyme; High-molecular-weight nonribosomal peptide/polyketide synthetase 2 2286543..2292668 Escherichia coli UMN026 7158487 YP_002412992.1 CDS irp NC_011751.1 2292756 2302247 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 11927258; Product type e : enzyme; High-molecular-weight nonribosomal peptide/polyketide synthetase 1 2292756..2302247 Escherichia coli UMN026 7156851 YP_002412993.1 CDS irp NC_011751.1 2302184 2303344 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11927258; Product type e : enzyme; Thiazolinyl-S-HMWP1 reductase YbtU 2302184..2303344 Escherichia coli UMN026 7156852 YP_002412994.1 CDS irp NC_011751.1 2303341 2304144 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thioesterase YbtT 2303341..2304144 Escherichia coli UMN026 7156853 YP_002412995.1 CDS irp NC_011751.1 2304148 2305725 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9818149, 11927258, 9709002; Product type e : enzyme; salicyl-AMP ligase YbtE 2304148..2305725 Escherichia coli UMN026 7156854 YP_002412996.1 CDS fyuA NC_011751.1 2305856 2307877 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7896707, 7984105; Product type rc : receptor; Yersiniabactin/pesticin outer membrane receptor (IRPC) 2305856..2307877 Escherichia coli UMN026 7156855 YP_002412997.1 CDS ECUMN_2279 NC_011751.1 2308691 2309674 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2308691..2309674 Escherichia coli UMN026 7156482 YP_002412998.1 CDS ECUMN_2280 NC_011751.1 2310018 2310203 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2310018..2310203 Escherichia coli UMN026 7155071 YP_002412999.1 CDS ECUMN_2281 NC_011751.1 2310188 2310769 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2310188..2310769 Escherichia coli UMN026 7155072 YP_002413000.1 CDS ECUMN_2282 NC_011751.1 2310759 2310968 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative lambdoid prophage protein 2310759..2310968 Escherichia coli UMN026 7155073 YP_002413001.1 CDS ECUMN_2283 NC_011751.1 2311211 2311339 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2311211..2311339 Escherichia coli UMN026 7155074 YP_002413002.1 CDS ECUMN_2284 NC_011751.1 2312196 2312924 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB1 component 2312196..2312924 Escherichia coli UMN026 7155075 YP_002413003.1 CDS ECUMN_2285 NC_011751.1 2312924 2313217 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB2 component 2312924..2313217 Escherichia coli UMN026 7155076 YP_002413004.1 CDS ECUMN_2286 NC_011751.1 2313230 2315968 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB4 component 2313230..2315968 Escherichia coli UMN026 7155077 YP_002413005.1 CDS ECUMN_2287 NC_011751.1 2315987 2316700 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB5 component 2315987..2316700 Escherichia coli UMN026 7155078 YP_002413006.1 CDS ECUMN_2288 NC_011751.1 2316708 2316950 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14731283, 15546668, 16428391; hypothetical protein 2316708..2316950 Escherichia coli UMN026 7155079 YP_002413007.1 CDS ECUMN_2289 NC_011751.1 2316954 2317298 D Evidence 7 : Gene remnant; Product type m : membrane component; type IV secretory pathway VirB6 component (fragment) 2316954..2317298 Escherichia coli UMN026 7155080 YP_002413008.1 CDS insH NC_011751.1 2317336 2318352 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage complement(2317336..2318352) Escherichia coli UMN026 7155081 YP_002413009.1 CDS ECUMN_2291 NC_011751.1 2318315 2319226 D Evidence 7 : Gene remnant; Product type m : membrane component; type IV secretory pathway VirB6 component (fragment) 2318315..2319226 Escherichia coli UMN026 7156831 YP_002413010.1 CDS ECUMN_2292 NC_011751.1 2319444 2320127 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB8 component 2319444..2320127 Escherichia coli UMN026 7155082 YP_002413011.1 CDS ECUMN_2293 NC_011751.1 2320124 2321032 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB9 component 2320124..2321032 Escherichia coli UMN026 7155083 YP_002413012.1 CDS ECUMN_2294 NC_011751.1 2321070 2322338 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB10 component 2321070..2322338 Escherichia coli UMN026 7155084 YP_002413013.1 CDS ECUMN_2295 NC_011751.1 2322328 2323353 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391, 2370849, 2233252; Product type ps : putative structure; putative type IV secretory pathway VirB11 component 2322328..2323353 Escherichia coli UMN026 7155085 YP_002413014.1 CDS ECUMN_2297 NC_011751.1 2323789 2324091 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; kikA from plasmid origin 2323789..2324091 Escherichia coli UMN026 7155087 YP_002413015.1 CDS ECUMN_2298 NC_011751.1 2324136 2324441 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14731283; hypothetical protein 2324136..2324441 Escherichia coli UMN026 7155088 YP_002413016.1 CDS ECUMN_2299 NC_011751.1 2325151 2327010 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10940031; Product type h : extrachromosomal origin; putative MobB mobilization protein 2325151..2327010 Escherichia coli UMN026 7155089 YP_002413017.1 CDS ECUMN_2300 NC_011751.1 2327014 2327766 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10940031, 11251827; Product type h : extrachromosomal origin; putative MobC mobilization protein 2327014..2327766 Escherichia coli UMN026 7155090 YP_002413018.1 CDS ECUMN_2301 NC_011751.1 2327959 2329098 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10686096; Product type pc : putative carrier; putative Antirestriction protein ardC complement(2327959..2329098) Escherichia coli UMN026 7155091 YP_002413019.1 CDS ECUMN_2302 NC_011751.1 2329140 2329373 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2329140..2329373 Escherichia coli UMN026 7155092 YP_002413020.1 CDS ECUMN_2303 NC_011751.1 2329496 2329807 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2329496..2329807 Escherichia coli UMN026 7155093 YP_002413021.1 CDS ECUMN_2304 NC_011751.1 2329909 2330904 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2329909..2330904 Escherichia coli UMN026 7155094 YP_002413022.1 CDS ECUMN_2305 NC_011751.1 2330901 2331989 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2330901..2331989 Escherichia coli UMN026 7155095 YP_002413023.1 CDS ECUMN_2306 NC_011751.1 2331974 2332480 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2331974..2332480 Escherichia coli UMN026 7155096 YP_002413024.1 CDS ECUMN_2307 NC_011751.1 2332477 2334357 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2332477..2334357 Escherichia coli UMN026 7155097 YP_002413025.1 CDS ECUMN_2308 NC_011751.1 2334641 2335660 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2334641..2335660) Escherichia coli UMN026 7155098 YP_002413026.1 CDS ECUMN_2309 NC_011751.1 2335692 2335829 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2335692..2335829) Escherichia coli UMN026 7155099 YP_002413027.1 CDS ECUMN_2310 NC_011751.1 2337029 2339305 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2337029..2339305 Escherichia coli UMN026 7155100 YP_002413028.1 CDS ECUMN_2312 NC_011751.1 2339420 2340520 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Retron-type reverse transcriptase 2339420..2340520 Escherichia coli UMN026 7155101 YP_002413029.1 CDS ECUMN_2313 NC_011751.1 2341176 2341670 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2341176..2341670) Escherichia coli UMN026 7155102 YP_002413030.1 CDS ECUMN_2314 NC_011751.1 2342042 2342320 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2342042..2342320) Escherichia coli UMN026 7155103 YP_002413031.1 CDS ECUMN_2315 NC_011751.1 2342428 2342571 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2342428..2342571) Escherichia coli UMN026 7155104 YP_002413032.1 CDS ECUMN_2316 NC_011751.1 2342466 2342945 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase complement(2342466..2342945) Escherichia coli UMN026 7155105 YP_002413033.1 CDS ECUMN_2317 NC_011751.1 2343400 2351457 D Evidence 2b : Function of strongly homologous gene; Product type pm : putative membrane component; putative invasin 2343400..2351457 Escherichia coli UMN026 7155106 YP_002413034.1 CDS ECUMN_2318 NC_011751.1 2351719 2352771 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2351719..2352771) Escherichia coli UMN026 7155107 YP_002413035.1 CDS shiA NC_011751.1 2353086 2354402 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 5332864, 9524262; Product type t : transporter; shikimate transporter 2353086..2354402 Escherichia coli UMN026 7155108 YP_002413036.1 CDS amn NC_011751.1 2354504 2355958 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2354504..2355958 Escherichia coli UMN026 7157923 YP_002413037.1 CDS yeeN NC_011751.1 2356300 2357016 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2356300..2357016 Escherichia coli UMN026 7155736 YP_002413038.1 CDS ECUMN_2322 NC_011751.1 2357252 2357431 D Evidence 6 : Doubtful CDS; hypothetical protein 2357252..2357431 Escherichia coli UMN026 7158806 YP_002413039.1 CDS yeeO NC_011751.1 2357647 2359287 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16042411; Product type pt : putative transporter; hypothetical protein complement(2357647..2359287) Escherichia coli UMN026 7155634 YP_002413040.1 CDS cbl NC_011751.1 2359408 2360358 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2359408..2360358) Escherichia coli UMN026 7155574 YP_002413041.1 CDS nac NC_011751.1 2360460 2361377 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2360460..2361377) Escherichia coli UMN026 7155921 YP_002413042.1 CDS erfK NC_011751.1 2361834 2362766 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein complement(2361834..2362766) Escherichia coli UMN026 7155575 YP_002413043.1 CDS cobT NC_011751.1 2362831 2363910 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2362831..2363910) Escherichia coli UMN026 7156268 YP_002413044.1 CDS cobS NC_011751.1 2363922 2364665 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2363922..2364665) Escherichia coli UMN026 7155993 YP_002413045.1 CDS cobU NC_011751.1 2364662 2365207 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase complement(2364662..2365207) Escherichia coli UMN026 7155992 YP_002413046.1 CDS ECUMN_2330 NC_011751.1 2365340 2365846 R Evidence 4 : Homologs of previously reported genes of unknown function; putative Cobalamin biosynthesis protein CbiG complement(2365340..2365846) Escherichia coli UMN026 7155994 YP_002413047.1 CDS ECUMN_2331 NC_011751.1 2365994 2366170 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2365994..2366170 Escherichia coli UMN026 7155110 YP_002413048.1 CDS pocR NC_011751.1 2366262 2367176 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8071226; Product type f : factor; propanediol utilization: transcriptional regulation complement(2366262..2367176) Escherichia coli UMN026 7155111 YP_002413049.1 CDS pduF NC_011751.1 2367379 2368227 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9352910; Product type m : membrane component; propanediol diffusion facilitator complement(2367379..2368227) Escherichia coli UMN026 7157484 YP_002413050.1 CDS ECUMN_2334 NC_011751.1 2368700 2368984 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduA-like protein 2368700..2368984 Escherichia coli UMN026 7157403 YP_002413051.1 CDS ECUMN_2335 NC_011751.1 2368981 2369793 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduB 2368981..2369793 Escherichia coli UMN026 7155112 YP_002413052.1 CDS pduC NC_011751.1 2369812 2371476 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; glycerol dehydratase large subunit 2369812..2371476 Escherichia coli UMN026 7155113 YP_002413053.1 CDS PduD NC_011751.1 2371486 2372154 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7706251, 12788698; Product type e : enzyme; propanediol utilization: diol dehydratase, medium subunit 2371486..2372154 Escherichia coli UMN026 7157400 YP_002413054.1 CDS pduE NC_011751.1 2372169 2372687 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; propanediol utilization diol dehydratase, small subunit 2372169..2372687 Escherichia coli UMN026 7157401 YP_002413055.1 CDS ECUMN_2339 NC_011751.1 2372697 2374529 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708, 12788698; Product type pe : putative enzyme; putative propanediol utilization diol dehydratase reactivation PduG 2372697..2374529 Escherichia coli UMN026 7157402 YP_002413056.1 CDS ECUMN_2340 NC_011751.1 2374519 2374869 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diol dehydratase reactivation pduH 2374519..2374869 Escherichia coli UMN026 7155114 YP_002413057.1 CDS ECUMN_2342 NC_011751.1 2375188 2375610 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization protein PduK 2375188..2375610 Escherichia coli UMN026 7155116 YP_002413058.1 CDS ECUMN_2343 NC_011751.1 2375613 2376245 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization protein PduL 2375613..2376245 Escherichia coli UMN026 7155117 YP_002413059.1 CDS ECUMN_2344 NC_011751.1 2376242 2376733 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization pduM 2376242..2376733 Escherichia coli UMN026 7155118 YP_002413060.1 CDS ECUMN_2345 NC_011751.1 2376737 2377012 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduN 2376737..2377012 Escherichia coli UMN026 7155119 YP_002413061.1 CDS ECUMN_2346 NC_011751.1 2377024 2378031 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization B12-like protein 2377024..2378031 Escherichia coli UMN026 7155120 YP_002413062.1 CDS ECUMN_2347 NC_011751.1 2378028 2379413 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : putative enzyme; putative CoA-dependent proprionaldehyde dehydrogenase pduP 2378028..2379413 Escherichia coli UMN026 7155121 YP_002413063.1 CDS ECUMN_2348 NC_011751.1 2379424 2380536 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : putative enzyme; putative propanediol utilization propanol dehydrogenase pduQ 2379424..2380536 Escherichia coli UMN026 7155122 YP_002413064.1 CDS ECUMN_2349 NC_011751.1 2380533 2381876 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization ferredoxin PduS 2380533..2381876 Escherichia coli UMN026 7155123 YP_002413065.1 CDS ECUMN_2350 NC_011751.1 2381879 2382433 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduT 2381879..2382433 Escherichia coli UMN026 7155124 YP_002413066.1 CDS ECUMN_2351 NC_011751.1 2382409 2382783 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduU 2382409..2382783 Escherichia coli UMN026 7155125 YP_002413067.1 CDS ECUMN_2352 NC_011751.1 2382788 2383231 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization protein PduV 2382788..2383231 Escherichia coli UMN026 7155126 YP_002413068.1 CDS yeeX NC_011751.1 2383332 2383727 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2383332..2383727) Escherichia coli UMN026 7155127 YP_002413069.1 CDS yeeA NC_011751.1 2383833 2384891 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2383833..2384891) Escherichia coli UMN026 7158813 YP_002413070.1 CDS sbmC NC_011751.1 2385090 2385563 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11850398, 9442027, 8709849; Product type r : regulator; DNA gyrase inhibitor complement(2385090..2385563) Escherichia coli UMN026 7158803 YP_002413071.1 CDS dacD NC_011751.1 2385682 2386848 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2385682..2386848) Escherichia coli UMN026 7157875 YP_002413072.1 CDS sbcB NC_011751.1 2387057 2388484 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2387057..2388484 Escherichia coli UMN026 7156102 YP_002413073.1 CDS yeeF NC_011751.1 2388559 2389917 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino-acid/amine transporter complement(2388559..2389917) Escherichia coli UMN026 7157871 YP_002413074.1 CDS yeeY NC_011751.1 2390184 2391113 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2390184..2391113) Escherichia coli UMN026 7158804 YP_002413075.1 CDS yeeZ NC_011751.1 2391159 2391983 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative epimerase, with NAD(P)-binding Rossmann-fold domain complement(2391159..2391983) Escherichia coli UMN026 7158814 YP_002413077.1 CDS hisG NC_011751.1 2392606 2393505 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2392606..2393505 Escherichia coli UMN026 7156682 YP_002413078.1 CDS hisD NC_011751.1 2393511 2394815 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2393511..2394815 Escherichia coli UMN026 7156678 YP_002413079.1 CDS hisC NC_011751.1 2394812 2395882 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2394812..2395882 Escherichia coli UMN026 7156676 YP_002413080.1 CDS hisB NC_011751.1 2395882 2396949 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2395882..2396949 Escherichia coli UMN026 7156675 YP_002413081.1 CDS hisH NC_011751.1 2396949 2397539 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2396949..2397539 Escherichia coli UMN026 7156674 YP_002413082.1 CDS hisA NC_011751.1 2397539 2398276 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2397539..2398276 Escherichia coli UMN026 7156679 YP_002413083.1 CDS hisF NC_011751.1 2398258 2399034 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2398258..2399034 Escherichia coli UMN026 7156673 YP_002413084.1 CDS hisI NC_011751.1 2399028 2399639 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 2399028..2399639 Escherichia coli UMN026 7156677 YP_002413085.1 CDS cld NC_011751.1 2399822 2400802 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98241528; Product type r : regulator; regulator of length of O-antigen component of lipopolysaccharide chains complement(2399822..2400802) Escherichia coli UMN026 7156680 YP_002413086.1 CDS ugd NC_011751.1 2400945 2402111 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150218, 96326333; Product type e : enzyme; UDP-glucose 6-dehydrogenase complement(2400945..2402111) Escherichia coli UMN026 7155977 YP_002413087.1 CDS gnd NC_011751.1 2402361 2403767 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2402361..2403767) Escherichia coli UMN026 7158164 YP_002413088.1 CDS ECUMN_2372 NC_011751.1 2403920 2405155 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative O antigen transporter Wzx complement(2403920..2405155) Escherichia coli UMN026 7156592 YP_002413089.1 CDS ECUMN_2373 NC_011751.1 2405197 2406528 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative O antigen polymerase wzy complement(2405197..2406528) Escherichia coli UMN026 7155128 YP_002413090.1 CDS manB NC_011751.1 2406712 2408175 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phosphomannomutase (PMM) complement(2406712..2408175) Escherichia coli UMN026 7155129 YP_002413091.1 CDS cpsB NC_011751.1 2408144 2409559 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; mannose-1-phosphate guanyltransferase complement(2408144..2409559) Escherichia coli UMN026 7157055 YP_002413092.1 CDS wbaD NC_011751.1 2409561 2410763 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Mannosyl transferase wbaD complement(2409561..2410763) Escherichia coli UMN026 7156002 YP_002413093.1 CDS wbaC NC_011751.1 2410756 2411793 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Mannosyl transferase WbaC complement(2410756..2411793) Escherichia coli UMN026 7158222 YP_002413094.1 CDS galF NC_011751.1 2412154 2413047 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF complement(2412154..2413047) Escherichia coli UMN026 7158221 YP_002413095.1 CDS wcaM NC_011751.1 2413222 2414616 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein complement(2413222..2414616) Escherichia coli UMN026 7156494 YP_002413096.1 CDS wcaL NC_011751.1 2414627 2415847 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme; putative glycosyl transferase complement(2414627..2415847) Escherichia coli UMN026 7158233 YP_002413097.1 CDS wcaK NC_011751.1 2415844 2417124 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333, 8759852, 11004393; Product type pe : putative enzyme; putative pyruvyl transferase complement(2415844..2417124) Escherichia coli UMN026 7158232 YP_002413098.1 CDS wzxC NC_011751.1 2417400 2418878 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 8759852; Product type pt : putative transporter; colanic acid exporter complement(2417400..2418878) Escherichia coli UMN026 7158231 YP_002413099.1 CDS wcaJ NC_011751.1 2418880 2420274 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase complement(2418880..2420274) Escherichia coli UMN026 7158238 YP_002413100.1 CDS cpsG NC_011751.1 2420329 2421699 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme; phosphomannomutase complement(2420329..2421699) Escherichia coli UMN026 7158230 YP_002413101.1 CDS cpsB NC_011751.1 2421892 2423328 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 85006781, 92048476, 93122523, 96326333, 7815923, 8759852; Product type e : enzyme; mannose-1-phosphate guanyltransferase complement(2421892..2423328) Escherichia coli UMN026 7156004 YP_002413102.1 CDS wcaI NC_011751.1 2423331 2424554 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15670885, 96326333; Product type pe : putative enzyme; putative glycosyl transferase complement(2423331..2424554) Escherichia coli UMN026 7156003 YP_002413103.1 CDS nudD NC_011751.1 2424551 2425030 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme; GDP-mannose mannosyl hydrolase complement(2424551..2425030) Escherichia coli UMN026 7158229 YP_002413104.1 CDS fcl NC_011751.1 2425033 2425998 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase complement(2425033..2425998) Escherichia coli UMN026 7157318 YP_002413105.1 CDS gmd NC_011751.1 2426001 2427122 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme; GDP-D-mannose dehydratase complement(2426001..2427122) Escherichia coli UMN026 7156312 YP_002413106.1 CDS wcaF NC_011751.1 2427149 2427697 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF complement(2427149..2427697) Escherichia coli UMN026 7156588 YP_002413107.1 CDS wcaE NC_011751.1 2427713 2428459 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11371548, 96326333, 8759852; Product type pe : putative enzyme; putative glycosyl transferase complement(2427713..2428459) Escherichia coli UMN026 7158228 YP_002413108.1 CDS wcaD NC_011751.1 2428470 2429687 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein complement(2428470..2429687) Escherichia coli UMN026 7158227 YP_002413109.1 CDS wcaC NC_011751.1 2429662 2430879 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme; putative glycosyl transferase complement(2429662..2430879) Escherichia coli UMN026 7158226 YP_002413110.1 CDS wcaB NC_011751.1 2430876 2431364 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB complement(2430876..2431364) Escherichia coli UMN026 7158225 YP_002413111.1 CDS wcaA NC_011751.1 2431367 2432206 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme; putative glycosyl transferase complement(2431367..2432206) Escherichia coli UMN026 7158224 YP_002413112.1 CDS wzc NC_011751.1 2432299 2434461 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2432299..2434461) Escherichia coli UMN026 7158223 YP_002413113.1 CDS wzb NC_011751.1 2434464 2434907 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2434464..2434907) Escherichia coli UMN026 7158237 YP_002413114.1 CDS wza NC_011751.1 2434913 2436052 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15090537, 96326333, 8759852, 8763957; Product type lp : lipoprotein; lipoprotein complement(2434913..2436052) Escherichia coli UMN026 7158236 YP_002413115.1 CDS yegH NC_011751.1 2436711 2438294 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 2436711..2438294 Escherichia coli UMN026 7158235 YP_002413116.1 CDS ECUMN_2400 NC_011751.1 2438369 2438707 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2438369..2438707 Escherichia coli UMN026 7158818 YP_002413117.1 CDS ECUMN_2401 NC_011751.1 2438679 2438987 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2438679..2438987 Escherichia coli UMN026 7155137 YP_002413118.1 CDS asmA NC_011751.1 2439040 2440893 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein complement(2439040..2440893) Escherichia coli UMN026 7155138 YP_002413119.1 CDS dcd NC_011751.1 2440915 2441496 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2440915..2441496) Escherichia coli UMN026 7155812 YP_002413120.1 CDS udk NC_011751.1 2441588 2442229 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2441588..2442229) Escherichia coli UMN026 7156113 YP_002413121.1 CDS yegE NC_011751.1 2442547 2445864 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein 2442547..2445864 Escherichia coli UMN026 7158162 YP_002413122.1 CDS alkA NC_011751.1 2445902 2446759 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase II complement(2445902..2446759) Escherichia coli UMN026 7158817 YP_002413123.1 CDS yegD NC_011751.1 2446893 2448245 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094528, 7940673, 7984428; Product type pf : putative factor; putative chaperone 2446893..2448245 Escherichia coli UMN026 7155724 YP_002413124.1 CDS yegI NC_011751.1 2448258 2450204 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2448258..2450204) Escherichia coli UMN026 7158816 YP_002413125.1 CDS yegJ NC_011751.1 2450405 2450866 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2450405..2450866 Escherichia coli UMN026 7158819 YP_002413126.1 CDS yegK NC_011751.1 2450931 2451692 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2450931..2451692) Escherichia coli UMN026 7158820 YP_002413127.1 CDS yegL NC_011751.1 2451689 2452348 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2451689..2452348) Escherichia coli UMN026 7158821 YP_002413128.1 CDS mdtA NC_011751.1 2453892 2455139 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2453892..2455139 Escherichia coli UMN026 7157842 YP_002413129.1 CDS mdtB NC_011751.1 2455139 2458261 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2455139..2458261 Escherichia coli UMN026 7157077 YP_002413130.1 CDS mdtC NC_011751.1 2458262 2461339 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2458262..2461339 Escherichia coli UMN026 7157078 YP_002413131.1 CDS mdtD NC_011751.1 2461340 2462755 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12107134, 21450803, 8282725; Product type t : transporter; multidrug efflux system protein MdtE 2461340..2462755 Escherichia coli UMN026 7157079 YP_002413132.1 CDS baeS NC_011751.1 2462752 2464155 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; signal transduction histidine-protein kinase BaeS 2462752..2464155 Escherichia coli UMN026 7157080 YP_002413133.1 CDS baeR NC_011751.1 2464152 2464874 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2464152..2464874 Escherichia coli UMN026 7155850 YP_002413134.1 CDS yegP NC_011751.1 2465054 2465386 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2465054..2465386 Escherichia coli UMN026 7155849 YP_002413135.1 CDS yegQ NC_011751.1 2465534 2466895 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 2465534..2466895 Escherichia coli UMN026 7158823 YP_002413136.1 CDS yegR NC_011751.1 2467224 2467541 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2467224..2467541) Escherichia coli UMN026 7157843 YP_002413137.1 CDS yegS NC_011751.1 2467956 2468855 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2467956..2468855 Escherichia coli UMN026 7158825 YP_002413138.1 CDS gatR NC_011751.1 2468937 2469716 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7772602; Product type r : regulator; Galactitol utilization operon repressor complement(2468937..2469716) Escherichia coli UMN026 7158826 YP_002413139.1 CDS gatD NC_011751.1 2469816 2470856 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2469816..2470856) Escherichia coli UMN026 7156514 YP_002413140.1 CDS gatC NC_011751.1 2470904 2472259 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76024805, 77192083, 97113438, 7772602; Product type t : transporter; galactitol-specific enzyme IIC component of PTS complement(2470904..2472259) Escherichia coli UMN026 7156513 YP_002413141.1 CDS gatB NC_011751.1 2472263 2472547 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2472263..2472547) Escherichia coli UMN026 7156512 YP_002413142.1 CDS gatA NC_011751.1 2472578 2473030 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2472578..2473030) Escherichia coli UMN026 7156511 YP_002413143.1 CDS gatZ NC_011751.1 2473040 2474302 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 97113438, 7772602, 8932697; Product type e : enzyme; D-tagatose 1,6-bisphosphate aldolase 2, subunit complement(2473040..2474302) Escherichia coli UMN026 7156510 YP_002413144.1 CDS gatY NC_011751.1 2474331 2475185 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2474331..2475185) Escherichia coli UMN026 7156516 YP_002413145.1 CDS fbaB NC_011751.1 2475413 2476465 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2475413..2476465) Escherichia coli UMN026 7156515 YP_002413146.1 CDS yegT NC_011751.1 2476722 2477999 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative hydrophilic substrate MFS superfamily transporter 2476722..2477999 Escherichia coli UMN026 7156310 YP_002413147.1 CDS yegU NC_011751.1 2477996 2479000 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative (phospho)hydrolase 2477996..2479000 Escherichia coli UMN026 7158827 YP_002413148.1 CDS yegV NC_011751.1 2478997 2479962 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative kinase 2478997..2479962 Escherichia coli UMN026 7158828 YP_002413149.1 CDS yegW NC_011751.1 2479936 2480682 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2479936..2480682) Escherichia coli UMN026 7158829 YP_002413150.1 CDS yegX NC_011751.1 2480734 2481552 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-bound hydrolase complement(2480734..2481552) Escherichia coli UMN026 7158830 YP_002413151.1 CDS thiD NC_011751.1 2481617 2482417 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2481617..2482417) Escherichia coli UMN026 7158831 YP_002413152.1 CDS thiM NC_011751.1 2482414 2483202 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2482414..2483202) Escherichia coli UMN026 7158053 YP_002413153.1 CDS yohL NC_011751.1 2483425 2483697 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2483425..2483697) Escherichia coli UMN026 7158060 YP_002413154.1 CDS rncA NC_011751.1 2483818 2484642 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2483818..2484642 Escherichia coli UMN026 7159563 YP_002413155.1 CDS yohN NC_011751.1 2484681 2485199 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2484681..2485199 Escherichia coli UMN026 7157709 YP_002413156.1 CDS yehA NC_011751.1 2485281 2486315 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative exported fimbrial-like adhesin protein complement(2485281..2486315) Escherichia coli UMN026 7159564 YP_002413157.1 CDS yehB NC_011751.1 2486331 2488811 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2486331..2488811) Escherichia coli UMN026 7158832 YP_002413158.1 CDS yehC NC_011751.1 2488827 2489501 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative membrane-associated pilin chaperone complement(2488827..2489501) Escherichia coli UMN026 7158833 YP_002413159.1 CDS yehD NC_011751.1 2489582 2490124 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin protein complement(2489582..2490124) Escherichia coli UMN026 7158834 YP_002413160.1 CDS yehE NC_011751.1 2490419 2490700 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2490419..2490700) Escherichia coli UMN026 7158835 YP_002413161.1 CDS mrp NC_011751.1 2490963 2492072 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91080852, 15601724, 2259334; Product type t : transporter; putative ATPase complement(2490963..2492072) Escherichia coli UMN026 7158836 YP_002413162.1 CDS metG NC_011751.1 2492204 2494237 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2492204..2494237 Escherichia coli UMN026 7157182 YP_002413163.1 CDS ECUMN_2447 NC_011751.1 2494378 2498175 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type ph : phenotype; molybdate metabolism protein 2494378..2498175 Escherichia coli UMN026 7157105 YP_002413164.1 CDS ECUMN_2448 NC_011751.1 2498188 2501949 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810, 12480890; Product type pr : putative regulator; putative molybdate metabolism regulator (molR-like) 2498188..2501949 Escherichia coli UMN026 7155139 YP_002413165.1 CDS yehI NC_011751.1 2501959 2505591 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2501959..2505591 Escherichia coli UMN026 7155140 YP_002413166.1 CDS yehK NC_011751.1 2505652 2505957 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2505652..2505957 Escherichia coli UMN026 7158837 YP_002413167.1 CDS yehL NC_011751.1 2507141 2508229 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16428726; Product type pf : putative factor; putative ABC superfamily protein 2507141..2508229 Escherichia coli UMN026 7158838 YP_002413168.1 CDS yehM NC_011751.1 2508240 2510519 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2508240..2510519 Escherichia coli UMN026 7158839 YP_002413169.1 CDS yehP NC_011751.1 2510512 2511648 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2510512..2511648 Escherichia coli UMN026 7158840 YP_002413170.1 CDS yehQ NC_011751.1 2511645 2513645 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2511645..2513645 Escherichia coli UMN026 7158841 YP_002413171.1 CDS yehR NC_011751.1 2513770 2514231 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type lp : lipoprotein; hypothetical protein 2513770..2514231 Escherichia coli UMN026 7158842 YP_002413172.1 CDS yehS NC_011751.1 2514273 2514743 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2514273..2514743) Escherichia coli UMN026 7158843 YP_002413173.1 CDS yehT NC_011751.1 2514790 2515509 R unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT complement(2514790..2515509) Escherichia coli UMN026 7158844 YP_002413174.1 CDS yehU NC_011751.1 2515506 2517191 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865, 15322361; Product type rc : receptor; sensory kinase in two-component system with YehT complement(2515506..2517191) Escherichia coli UMN026 7158845 YP_002413175.1 CDS mlrA NC_011751.1 2517413 2518144 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11489123; Product type r : regulator; DNA-binding transcriptional regulator 2517413..2518144 Escherichia coli UMN026 7158846 YP_002413176.1 CDS yehW NC_011751.1 2518292 2519023 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease complement(2518292..2519023) Escherichia coli UMN026 7157138 YP_002413177.1 CDS yehX NC_011751.1 2519028 2519954 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein complement(2519028..2519954) Escherichia coli UMN026 7158847 YP_002413178.1 CDS yehY NC_011751.1 2519947 2521104 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease complement(2519947..2521104) Escherichia coli UMN026 7158848 YP_002413179.1 CDS yehZ NC_011751.1 2521111 2522028 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15251200; Product type pt : putative transporter; putative ABC transporter periplasmic-binding protein complement(2521111..2522028) Escherichia coli UMN026 7158849 YP_002413180.1 CDS bglX NC_011751.1 2522177 2524474 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96303506; Product type e : enzyme; beta-D-glucoside glucohydrolase, periplasmic complement(2522177..2524474) Escherichia coli UMN026 7158850 YP_002413181.1 CDS dld NC_011751.1 2524670 2526385 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2524670..2526385 Escherichia coli UMN026 7155875 YP_002413182.1 CDS pbpG NC_011751.1 2526423 2527355 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2526423..2527355) Escherichia coli UMN026 7156178 YP_002413183.1 CDS yohC NC_011751.1 2527529 2528116 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2527529..2528116) Escherichia coli UMN026 7157395 YP_002413184.1 CDS yohD NC_011751.1 2528286 2528864 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2528286..2528864 Escherichia coli UMN026 7159557 YP_002413185.1 CDS yohF NC_011751.1 2528983 2529744 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; acetoin dehydrogenase complement(2528983..2529744) Escherichia coli UMN026 7159558 YP_002413186.1 CDS yohG NC_011751.1 2529797 2530885 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2529797..2530885) Escherichia coli UMN026 7159559 YP_002413187.1 CDS dusC NC_011751.1 2531913 2532860 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA -dihydrouridine synthase C complement(2531913..2532860) Escherichia coli UMN026 7159560 YP_002413188.1 CDS yohJ NC_011751.1 2533099 2533497 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2533099..2533497 Escherichia coli UMN026 7156213 YP_002413189.1 CDS yohK NC_011751.1 2533494 2534189 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2533494..2534189 Escherichia coli UMN026 7159561 YP_002413190.1 CDS cdd NC_011751.1 2534319 2535203 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2534319..2535203 Escherichia coli UMN026 7159562 YP_002413191.1 CDS sanA NC_011751.1 2535353 2536072 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96125233, 1567863, 8550448; hypothetical protein 2535353..2536072 Escherichia coli UMN026 7155937 YP_002413192.1 CDS yeiS NC_011751.1 2536075 2536314 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2536075..2536314 Escherichia coli UMN026 7157864 YP_002413193.1 CDS yeiT NC_011751.1 2536633 2537871 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 2536633..2537871 Escherichia coli UMN026 7158863 YP_002413194.1 CDS yeiA NC_011751.1 2537865 2539100 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2537865..2539100 Escherichia coli UMN026 7158864 YP_002413195.1 CDS mglC NC_011751.1 2539171 2540181 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component complement(2539171..2540181) Escherichia coli UMN026 7158851 YP_002413196.1 CDS mglA NC_011751.1 2540197 2541717 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2540197..2541717) Escherichia coli UMN026 7157117 YP_002413197.1 CDS mglB NC_011751.1 2541778 2542776 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87286407, 92049246, 1719366, 3057628, 3302609, 3600760, 6340108, 6885805, 7012152, 9298646; Product type t : transporter; methyl-galactoside ABC transporter periplasmic-binding protein complement(2541778..2542776) Escherichia coli UMN026 7157115 YP_002413198.1 CDS galS NC_011751.1 2543056 2544096 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2543056..2544096) Escherichia coli UMN026 7157116 YP_002413199.1 CDS ECUMN_2485 NC_011751.1 2544086 2544289 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2544086..2544289 Escherichia coli UMN026 7156499 YP_002413200.1 CDS yeiB NC_011751.1 2544238 2545395 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2544238..2545395) Escherichia coli UMN026 7155141 YP_002413201.1 CDS folE NC_011751.1 2545412 2546080 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2545412..2546080) Escherichia coli UMN026 7158852 YP_002413202.1 CDS ECUMN_2488 NC_011751.1 2546234 2546410 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2546234..2546410 Escherichia coli UMN026 7156427 YP_002413203.1 CDS frmC NC_011751.1 2546338 2547174 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800; Product type e : enzyme; S-formylglutathione hydrolase 2546338..2547174 Escherichia coli UMN026 7155142 YP_002413204.1 CDS cirA NC_011751.1 2547206 2549185 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2547206..2549185) Escherichia coli UMN026 7156441 YP_002413205.1 CDS ECUMN_2491 NC_011751.1 2549178 2549381 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2549178..2549381) Escherichia coli UMN026 7155965 YP_002413206.1 CDS lysP NC_011751.1 2549478 2550947 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250419, 94252996, 1315732, 7551055; Product type t : transporter; lysine transporter complement(2549478..2550947) Escherichia coli UMN026 7155143 YP_002413207.1 CDS yeiE NC_011751.1 2551152 2552033 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12400704, 1315732; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2551152..2552033) Escherichia coli UMN026 7157031 YP_002413208.1 CDS yeiH NC_011751.1 2552132 2553181 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2552132..2553181 Escherichia coli UMN026 7158854 YP_002413209.1 CDS nfo NC_011751.1 2553255 2554112 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2553255..2554112 Escherichia coli UMN026 7158855 YP_002413210.1 CDS yeiI NC_011751.1 2554115 2555203 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2554115..2555203 Escherichia coli UMN026 7157267 YP_002413211.1 CDS yeiJ NC_011751.1 2555310 2556560 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium/proton nucleoside transporter complement(2555310..2556560) Escherichia coli UMN026 7158856 YP_002413212.1 CDS rihB NC_011751.1 2556660 2557601 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2556660..2557601) Escherichia coli UMN026 7158857 YP_002413213.1 CDS yeiL NC_011751.1 2557770 2558429 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2557770..2558429 Escherichia coli UMN026 7157689 YP_002413214.1 CDS yeiM NC_011751.1 2558497 2559747 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium/proton nucleoside transporter complement(2558497..2559747) Escherichia coli UMN026 7158858 YP_002413215.1 CDS yeiN NC_011751.1 2559841 2560779 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2559841..2560779) Escherichia coli UMN026 7158859 YP_002413216.1 CDS yeiC NC_011751.1 2560767 2561708 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(2560767..2561708) Escherichia coli UMN026 7158860 YP_002413217.1 CDS fruA NC_011751.1 2562132 2563823 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC complement(2562132..2563823) Escherichia coli UMN026 7158853 YP_002413218.1 CDS fruK NC_011751.1 2563840 2564778 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2563840..2564778) Escherichia coli UMN026 7156445 YP_002413219.1 CDS fruB NC_011751.1 2564778 2565908 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(2564778..2565908) Escherichia coli UMN026 7156447 YP_002413220.1 CDS setB NC_011751.1 2566276 2567457 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438463, 10209755; Product type t : transporter; lactose/glucose efflux system 2566276..2567457 Escherichia coli UMN026 7156446 YP_002413221.1 CDS ECUMN_2507 NC_011751.1 2567454 2567840 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2567454..2567840) Escherichia coli UMN026 7157901 YP_002413222.1 CDS ECUMN_2508 NC_011751.1 2567608 2568435 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2567608..2568435 Escherichia coli UMN026 7155144 YP_002413223.1 CDS yeiQ NC_011751.1 2568658 2570124 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar dehydrogenase 2568658..2570124 Escherichia coli UMN026 7155145 YP_002413224.1 CDS yeiR NC_011751.1 2570242 2571228 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2570242..2571228 Escherichia coli UMN026 7158861 YP_002413225.1 CDS yeiU NC_011751.1 2571267 2571980 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 2571267..2571980 Escherichia coli UMN026 7158862 YP_002413226.1 CDS spr NC_011751.1 2572392 2572958 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein 2572392..2572958 Escherichia coli UMN026 7158865 YP_002413227.1 CDS rtn NC_011751.1 2573139 2574695 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2573139..2574695 Escherichia coli UMN026 7157966 YP_002413228.1 CDS yejA NC_011751.1 2574777 2576591 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter periplasmic-binding protein 2574777..2576591 Escherichia coli UMN026 7157815 YP_002413229.1 CDS yejB NC_011751.1 2576592 2577686 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter permease 2576592..2577686 Escherichia coli UMN026 7158866 YP_002413230.1 CDS yejE NC_011751.1 2577686 2578711 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter permease 2577686..2578711 Escherichia coli UMN026 7158867 YP_002413231.1 CDS yejF NC_011751.1 2578713 2580302 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter ATP-binding protein 2578713..2580302 Escherichia coli UMN026 7158868 YP_002413232.1 CDS yejG NC_011751.1 2580306 2580650 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2580306..2580650) Escherichia coli UMN026 7158869 YP_002413233.1 CDS bcr NC_011751.1 2580983 2582173 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system complement(2580983..2582173) Escherichia coli UMN026 7158870 YP_002413234.1 CDS rsuA NC_011751.1 2582201 2582896 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2582201..2582896) Escherichia coli UMN026 7155856 YP_002413235.1 CDS yejH NC_011751.1 2583046 2584806 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleic acid ATP-dependent helicase 2583046..2584806 Escherichia coli UMN026 7157805 YP_002413236.1 CDS rplY NC_011751.1 2584931 2585215 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2584931..2585215 Escherichia coli UMN026 7158871 YP_002413237.1 CDS yejK NC_011751.1 2585354 2586361 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99296598, 10368163; Product type f : factor; nucleoid-associated protein NdpA complement(2585354..2586361) Escherichia coli UMN026 7157747 YP_002413238.1 CDS yejL NC_011751.1 2586543 2586770 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2586543..2586770 Escherichia coli UMN026 7158872 YP_002413239.1 CDS yejM NC_011751.1 2586790 2588550 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 2586790..2588550 Escherichia coli UMN026 7158873 YP_002413240.1 CDS yejO NC_011751.1 2588804 2591314 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659678; Product type pt : putative transporter; putative autotransporter outer membrane protein; type V secretion complement(2588804..2591314) Escherichia coli UMN026 7155577 YP_002413241.1 CDS narP NC_011751.1 2591715 2592362 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2591715..2592362 Escherichia coli UMN026 7158875 YP_002413242.1 CDS ccmH NC_011751.1 2592397 2593449 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 91194558, 95362656, 9914305, 7635817; Product type pe : putative enzyme; heme lyase, CcmH subunit complement(2592397..2593449) Escherichia coli UMN026 7157253 YP_002413243.1 CDS ccmG NC_011751.1 2593446 2594003 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 9716493, 9770295, 11256948, 11350062, 11843181, 7635817, 9537397; Product type e : enzyme; periplasmic thioredoxin of cytochrome c-type biogenesis complement(2593446..2594003) Escherichia coli UMN026 7155935 YP_002413244.1 CDS ccmF NC_011751.1 2594000 2595943 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 8842153, 91194558, 95362656, 9716493, 7635817; Product type e : enzyme; heme lyase, CcmF subunit complement(2594000..2595943) Escherichia coli UMN026 7155934 YP_002413245.1 CDS ccmE NC_011751.1 2595940 2596419 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2595940..2596419) Escherichia coli UMN026 7155933 YP_002413246.1 CDS ccmD NC_011751.1 2596416 2596625 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type f : factor; cytochrome c biogenesis protein complement(2596416..2596625) Escherichia coli UMN026 7155932 YP_002413247.1 CDS ccmC NC_011751.1 2596622 2597359 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 14532274, 21413853, 95362656, 7635817; Product type t : transporter; heme exporter membrane protein complement(2596622..2597359) Escherichia coli UMN026 7155931 YP_002413248.1 CDS ccmB NC_011751.1 2597401 2598063 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type t : transporter; heme exporter membrane protein complement(2597401..2598063) Escherichia coli UMN026 7155930 YP_002413249.1 CDS ccmA NC_011751.1 2598060 2598683 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2598060..2598683) Escherichia coli UMN026 7155929 YP_002413250.1 CDS napC NC_011751.1 2598696 2599298 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2598696..2599298) Escherichia coli UMN026 7155928 YP_002413251.1 CDS napB NC_011751.1 2599308 2599757 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2599308..2599757) Escherichia coli UMN026 7157242 YP_002413252.1 CDS napH NC_011751.1 2599754 2600617 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2599754..2600617) Escherichia coli UMN026 7157241 YP_002413253.1 CDS napG NC_011751.1 2600604 2601299 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2600604..2601299) Escherichia coli UMN026 7157246 YP_002413254.1 CDS napA NC_011751.1 2601306 2603792 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2601306..2603792) Escherichia coli UMN026 7157245 YP_002413255.1 CDS napD NC_011751.1 2603789 2604052 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96228696, 99395037; Product type f : factor; assembly protein for periplasmic nitrate reductase complement(2603789..2604052) Escherichia coli UMN026 7157240 YP_002413256.1 CDS napF NC_011751.1 2604042 2604536 R Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein complement(2604042..2604536) Escherichia coli UMN026 7157243 YP_002413257.1 CDS ECUMN_2544 NC_011751.1 2604636 2604809 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2604636..2604809 Escherichia coli UMN026 7157244 YP_002413258.1 CDS eco NC_011751.1 2604944 2605432 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2604944..2605432 Escherichia coli UMN026 7155146 YP_002413259.1 CDS mqo NC_011751.1 2605580 2607226 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2605580..2607226) Escherichia coli UMN026 7156224 YP_002413260.1 CDS yojI NC_011751.1 2607444 2609087 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding component complement(2607444..2609087) Escherichia coli UMN026 7157170 YP_002413261.1 CDS alkB NC_011751.1 2609163 2609813 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12226668, 12517444, 12862460, 14527653, 87057220, 88151899, 92017669, 3536913, 3887409, 7928996; Product type e : enzyme; oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions complement(2609163..2609813) Escherichia coli UMN026 7159565 YP_002413262.1 CDS ada NC_011751.1 2609813 2610877 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91073391, 93272965, 94252990; Product type r : regulator; bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase complement(2609813..2610877) Escherichia coli UMN026 7155725 YP_002413263.1 CDS yojL NC_011751.1 2610951 2612006 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2610951..2612006) Escherichia coli UMN026 7155695 YP_002413264.1 CDS ompC NC_011751.1 2612118 2613221 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2612118..2613221) Escherichia coli UMN026 7159566 YP_002413265.1 CDS rcsD NC_011751.1 2613960 2616632 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 21206231, 2404948, 7984428; Product type r : regulator; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2613960..2616632 Escherichia coli UMN026 7157132 YP_002413266.1 CDS rcsB NC_011751.1 2616649 2617299 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2616649..2617299 Escherichia coli UMN026 7157631 YP_002413267.1 CDS rcsC NC_011751.1 2617499 2620300 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 14651646, 20032358, 21450811, 88227838, 90130299, 92048476, 9209051, 2404948, 8366025; Product type r : regulator; hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2617499..2620300) Escherichia coli UMN026 7157629 YP_002413268.1 CDS ECUMN_2556 NC_011751.1 2620418 2620621 D hypothetical protein 2620418..2620621 Escherichia coli UMN026 7157630 YP_002413269.1 CDS atoS NC_011751.1 2620515 2622341 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2620515..2622341 Escherichia coli UMN026 7155147 YP_002413270.1 CDS atoC NC_011751.1 2622338 2623723 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2622338..2623723 Escherichia coli UMN026 7155832 YP_002413271.1 CDS atoD NC_011751.1 2623919 2624581 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2623919..2624581 Escherichia coli UMN026 7155829 YP_002413272.1 CDS atoA NC_011751.1 2624581 2625231 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit beta 2624581..2625231 Escherichia coli UMN026 7155830 YP_002413273.1 CDS atoE NC_011751.1 2625228 2626550 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type t : transporter; short chain fatty acid transporter 2625228..2626550 Escherichia coli UMN026 7155827 YP_002413274.1 CDS atoB NC_011751.1 2626581 2627765 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA acetyltransferase 2626581..2627765 Escherichia coli UMN026 7155831 YP_002413275.1 CDS yfaP NC_011751.1 2627839 2628615 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2627839..2628615) Escherichia coli UMN026 7155828 YP_002413276.1 CDS yfaQ NC_011751.1 2628620 2630269 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2628620..2630269) Escherichia coli UMN026 7158881 YP_002413277.1 CDS ECUMN_2565 NC_011751.1 2630270 2634889 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative large extracellular alpha-helical protein complement(2630270..2634889) Escherichia coli UMN026 7158882 YP_002413278.1 CDS yfaT NC_011751.1 2634808 2635431 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2634808..2635431) Escherichia coli UMN026 7155148 YP_002413279.1 CDS yfaA NC_011751.1 2635428 2637116 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2635428..2637116) Escherichia coli UMN026 7158883 YP_002413280.1 CDS gyrA NC_011751.1 2637265 2639892 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2637265..2639892) Escherichia coli UMN026 7158876 YP_002413281.1 CDS ubiG NC_011751.1 2640039 2640761 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2640039..2640761 Escherichia coli UMN026 7156631 YP_002413282.1 CDS yfaL NC_011751.1 2640822 2644535 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type f : factor; adhesin complement(2640822..2644535) Escherichia coli UMN026 7158158 YP_002413283.1 CDS nrdA NC_011751.1 2645231 2647516 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2645231..2647516 Escherichia coli UMN026 7158879 YP_002413284.1 CDS nrdB NC_011751.1 2647750 2648880 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2647750..2648880 Escherichia coli UMN026 7157298 YP_002413285.1 CDS yfaE NC_011751.1 2648880 2649134 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin YfaE 2648880..2649134 Escherichia coli UMN026 7157299 YP_002413286.1 CDS inaA NC_011751.1 2649188 2649838 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165728, 1537798, 6087316; hypothetical protein complement(2649188..2649838) Escherichia coli UMN026 7158878 YP_002413287.1 CDS ECUMN_2575 NC_011751.1 2649919 2651109 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11206551, 11258796; Product type pt : putative transporter; putative antibiotic efflux protein complement(2649919..2651109) Escherichia coli UMN026 7156810 YP_002413288.1 CDS ECUMN_2576 NC_011751.1 2651261 2652139 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptional regulator 2651261..2652139 Escherichia coli UMN026 7155149 YP_002413289.1 CDS ECUMN_2578 NC_011751.1 2652569 2653675 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2652569..2653675 Escherichia coli UMN026 7155150 YP_002413290.1 CDS glpQ NC_011751.1 2653896 2654972 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2653896..2654972) Escherichia coli UMN026 7155151 YP_002413291.1 CDS glpT NC_011751.1 2654977 2656335 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2654977..2656335) Escherichia coli UMN026 7156569 YP_002413292.1 CDS glpA NC_011751.1 2656608 2658236 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2656608..2658236 Escherichia coli UMN026 7156571 YP_002413293.1 CDS glpB NC_011751.1 2658226 2659485 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2658226..2659485 Escherichia coli UMN026 7156561 YP_002413294.1 CDS glpC NC_011751.1 2659482 2660672 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2659482..2660672 Escherichia coli UMN026 7156562 YP_002413295.1 CDS yfaD NC_011751.1 2660865 2661824 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2660865..2661824 Escherichia coli UMN026 7156563 YP_002413296.1 CDS ypaA NC_011751.1 2661837 2662034 D Evidence 7 : Gene remnant; hypothetical protein 2661837..2662034 Escherichia coli UMN026 7158877 YP_002413297.1 CDS yfaU NC_011751.1 2662075 2662878 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12454498, 16511168, 8550403; Product type pe : putative enzyme; putative aldolase complement(2662075..2662878) Escherichia coli UMN026 7159567 YP_002413298.1 CDS yfaV NC_011751.1 2662895 2664136 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative carboxylate transporter; phthalate permease family complement(2662895..2664136) Escherichia coli UMN026 7158884 YP_002413299.1 CDS ydcM NC_011751.1 2664166 2665374 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase complement(2664166..2665374) Escherichia coli UMN026 7158885 YP_002413300.1 CDS ECUMN_2589 NC_011751.1 2665352 2665498 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2665352..2665498) Escherichia coli UMN026 7158610 YP_002413301.1 CDS yfaY NC_011751.1 2665857 2667065 R Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A complement(2665857..2667065) Escherichia coli UMN026 7155152 YP_002413302.1 CDS yfaZ NC_011751.1 2667165 2667707 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative outer membrane porin protein complement(2667165..2667707) Escherichia coli UMN026 7158886 YP_002413303.1 CDS yfaO NC_011751.1 2667986 2668411 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme; putative NUDIX hydrolase 2667986..2668411 Escherichia coli UMN026 7158887 YP_002413304.1 CDS ais NC_011751.1 2668450 2669052 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2668450..2669052) Escherichia coli UMN026 7158880 YP_002413305.1 CDS yfbE NC_011751.1 2669342 2670499 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2669342..2670499 Escherichia coli UMN026 7155720 YP_002413306.1 CDS yfbF NC_011751.1 2670503 2671471 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2670503..2671471 Escherichia coli UMN026 7158889 YP_002413307.1 CDS yfbG NC_011751.1 2671471 2673453 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2671471..2673453 Escherichia coli UMN026 7158890 YP_002413308.1 CDS yfbH NC_011751.1 2673450 2674340 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2673450..2674340 Escherichia coli UMN026 7158891 YP_002413309.1 CDS arnT NC_011751.1 2674340 2675992 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2674340..2675992 Escherichia coli UMN026 7158892 YP_002413310.1 CDS yfbW NC_011751.1 2675989 2676324 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2675989..2676324 Escherichia coli UMN026 7155782 YP_002413311.1 CDS yfbJ NC_011751.1 2676042 2676710 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2676042..2676710 Escherichia coli UMN026 7158902 YP_002413312.1 CDS pmrD NC_011751.1 2676704 2676970 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96015440, 15569938; Product type pt : putative transporter; polymyxin resistance protein B complement(2676704..2676970) Escherichia coli UMN026 7158893 YP_002413313.1 CDS menE NC_011751.1 2677080 2678435 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96186953, 8626063; Product type e : enzyme; O-succinylbenzoic acid--CoA ligase complement(2677080..2678435) Escherichia coli UMN026 7157477 YP_002413314.1 CDS menC NC_011751.1 2678432 2679394 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2678432..2679394) Escherichia coli UMN026 7157097 YP_002413315.1 CDS menB NC_011751.1 2679394 2680251 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2679394..2680251) Escherichia coli UMN026 7157095 YP_002413316.1 CDS yfbB NC_011751.1 2680266 2681024 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(2680266..2681024) Escherichia coli UMN026 7157094 YP_002413317.1 CDS menD NC_011751.1 2681021 2682691 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2681021..2682691) Escherichia coli UMN026 7158888 YP_002413318.1 CDS menF NC_011751.1 2682780 2684075 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150206, 96140724, 2666397, 7984428, 8549818, 8764478; Product type e : enzyme; isochorismate synthase 2 complement(2682780..2684075) Escherichia coli UMN026 7157096 YP_002413319.1 CDS elaB NC_011751.1 2684154 2684459 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2684154..2684459) Escherichia coli UMN026 7157098 YP_002413320.1 CDS elaA NC_011751.1 2684514 2684975 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(2684514..2684975) Escherichia coli UMN026 7156235 YP_002413321.1 CDS elaC NC_011751.1 2685040 2685957 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2685040..2685957 Escherichia coli UMN026 7156234 YP_002413322.1 CDS elaD NC_011751.1 2686148 2687356 D ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2686148..2687356 Escherichia coli UMN026 7156236 YP_002413323.1 CDS yfbL NC_011751.1 2687746 2688717 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated peptidase 2687746..2688717 Escherichia coli UMN026 7156237 YP_002413324.1 CDS yfbM NC_011751.1 2688820 2689323 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2688820..2689323 Escherichia coli UMN026 7158894 YP_002413325.1 CDS nuoN NC_011751.1 2689391 2690668 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2689391..2690668) Escherichia coli UMN026 7158895 YP_002413326.1 CDS nuoM NC_011751.1 2690855 2692384 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2690855..2692384) Escherichia coli UMN026 7157335 YP_002413327.1 CDS nuoL NC_011751.1 2692548 2694389 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2692548..2694389) Escherichia coli UMN026 7157334 YP_002413328.1 CDS nuoK NC_011751.1 2694386 2694688 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2694386..2694688) Escherichia coli UMN026 7157333 YP_002413329.1 CDS nuoJ NC_011751.1 2694685 2695239 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2694685..2695239) Escherichia coli UMN026 7157332 YP_002413330.1 CDS nuoI NC_011751.1 2695251 2695793 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2695251..2695793) Escherichia coli UMN026 7157331 YP_002413331.1 CDS nuoH NC_011751.1 2695808 2696785 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2695808..2696785) Escherichia coli UMN026 7157330 YP_002413332.1 CDS nuoG NC_011751.1 2696782 2699514 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2696782..2699514) Escherichia coli UMN026 7157329 YP_002413333.1 CDS nuoF NC_011751.1 2699561 2700898 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2699561..2700898) Escherichia coli UMN026 7157328 YP_002413334.1 CDS nuoE NC_011751.1 2700895 2701395 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2700895..2701395) Escherichia coli UMN026 7157327 YP_002413335.1 CDS nuoC NC_011751.1 2701398 2703200 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2701398..2703200) Escherichia coli UMN026 7157326 YP_002413336.1 CDS nuoB NC_011751.1 2703294 2703956 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2703294..2703956) Escherichia coli UMN026 7157325 YP_002413337.1 CDS nuoA NC_011751.1 2703972 2704415 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2703972..2704415) Escherichia coli UMN026 7157324 YP_002413338.1 CDS lrhA NC_011751.1 2705045 2705983 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123461, 9882671, 7565112; Product type r : regulator; flagellar, motility and chemotaxis genes DNA-binding transcriptional repressor complement(2705045..2705983) Escherichia coli UMN026 7157323 YP_002413339.1 CDS yfbQ NC_011751.1 2706903 2708120 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2706903..2708120 Escherichia coli UMN026 7157017 YP_002413340.1 CDS yfbR NC_011751.1 2708204 2708803 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489502; Product type e : enzyme; hypothetical protein 2708204..2708803 Escherichia coli UMN026 7158896 YP_002413341.1 CDS yfbS NC_011751.1 2708862 2710694 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(2708862..2710694) Escherichia coli UMN026 7158897 YP_002413342.1 CDS yfbT NC_011751.1 2710781 2711431 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphatase complement(2710781..2711431) Escherichia coli UMN026 7158898 YP_002413343.1 CDS yfbU NC_011751.1 2711442 2711936 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2711442..2711936) Escherichia coli UMN026 7158899 YP_002413344.1 CDS yfbV NC_011751.1 2712019 2712474 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2712019..2712474) Escherichia coli UMN026 7158900 YP_002413345.1 CDS ackA NC_011751.1 2712812 2714014 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2712812..2714014 Escherichia coli UMN026 7158901 YP_002413346.1 CDS pta NC_011751.1 2714089 2716233 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2714089..2716233 Escherichia coli UMN026 7155680 YP_002413347.1 CDS yfcC NC_011751.1 2716423 2717943 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pc : putative carrier; hypothetical protein 2716423..2717943 Escherichia coli UMN026 7157561 YP_002413348.1 CDS yfcD NC_011751.1 2717976 2718518 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme; putative NUDIX hydrolase complement(2717976..2718518) Escherichia coli UMN026 7158904 YP_002413349.1 CDS yfcE NC_011751.1 2718576 2719130 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; phosphodiesterase complement(2718576..2719130) Escherichia coli UMN026 7158905 YP_002413350.1 CDS yfcF NC_011751.1 2719183 2719827 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(2719183..2719827) Escherichia coli UMN026 7158906 YP_002413351.1 CDS yfcG NC_011751.1 2719963 2720610 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; glutathione S-transferase 2719963..2720610 Escherichia coli UMN026 7158907 YP_002413352.1 CDS folX NC_011751.1 2720667 2721029 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2720667..2721029 Escherichia coli UMN026 7158908 YP_002413353.1 CDS yfcH NC_011751.1 2721050 2721943 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme; hypothetical protein 2721050..2721943 Escherichia coli UMN026 7156431 YP_002413354.1 CDS yfcI NC_011751.1 2721991 2722881 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase complement(2721991..2722881) Escherichia coli UMN026 7158909 YP_002413355.1 CDS hisP NC_011751.1 2723077 2723850 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284, 91060556; Product type t : transporter; histidine/lysine/arginine/ornithine transporter subunit complement(2723077..2723850) Escherichia coli UMN026 7158910 YP_002413356.1 CDS hisM NC_011751.1 2723858 2724574 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein complement(2723858..2724574) Escherichia coli UMN026 7156684 YP_002413357.1 CDS hisQ NC_011751.1 2724571 2725257 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein complement(2724571..2725257) Escherichia coli UMN026 7156683 YP_002413358.1 CDS hisJ NC_011751.1 2725347 2726129 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 6449635, 8161536, 9298646, 9600841, 9740056; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein complement(2725347..2726129) Escherichia coli UMN026 7156685 YP_002413359.1 CDS argT NC_011751.1 2726350 2727132 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4583243, 87308226, 3040734, 9298646; Product type t : transporter; lysine/arginine/ornithine ABC transporter periplasmic-binding protein complement(2726350..2727132) Escherichia coli UMN026 7156681 YP_002413360.1 CDS ubiX NC_011751.1 2727398 2727967 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2727398..2727967) Escherichia coli UMN026 7155781 YP_002413361.1 CDS purF NC_011751.1 2728062 2729579 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2728062..2729579) Escherichia coli UMN026 7158160 YP_002413362.1 CDS cvpA NC_011751.1 2729616 2730104 R membrane protein required for colicin V production; colicin V production protein complement(2729616..2730104) Escherichia coli UMN026 7157577 YP_002413363.1 CDS dedD NC_011751.1 2730363 2731025 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3040734; hypothetical protein complement(2730363..2731025) Escherichia coli UMN026 7156058 YP_002413364.1 CDS folC NC_011751.1 2731015 2732283 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3040739, 91112811, 92041808, 1989505, 3040734; Product type e : enzyme; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2731015..2732283) Escherichia coli UMN026 7156135 YP_002413365.1 CDS accD NC_011751.1 2732353 2733267 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2732353..2733267) Escherichia coli UMN026 7156425 YP_002413366.1 CDS dedA NC_011751.1 2733423 2734082 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029016, 3040734, 7678242; Product type pm : putative membrane component; hypothetical protein complement(2733423..2734082) Escherichia coli UMN026 7155674 YP_002413367.1 CDS truA NC_011751.1 2734165 2734977 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2734165..2734977) Escherichia coli UMN026 7156134 YP_002413368.1 CDS usg NC_011751.1 2734977 2735990 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 92380957, 92380982, 93123150, 2681152, 2991861, 3029016; Product type pe : putative enzyme; putative semialdehyde dehydrogenase complement(2734977..2735990) Escherichia coli UMN026 7158125 YP_002413369.1 CDS pdxB NC_011751.1 2736056 2737192 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90036695, 91035267, 2681152, 2991861, 3029016; Product type e : enzyme; erythronate-4-phosphate dehydrogenase complement(2736056..2737192) Escherichia coli UMN026 7158191 YP_002413370.1 CDS flk NC_011751.1 2737291 2738286 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2737291..2738286 Escherichia coli UMN026 7157405 YP_002413371.1 CDS yfcJ NC_011751.1 2738283 2739461 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein complement(2738283..2739461) Escherichia coli UMN026 7156416 YP_002413372.1 CDS fabB NC_011751.1 2739746 2740966 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase I complement(2739746..2740966) Escherichia coli UMN026 7158911 YP_002413373.1 CDS mnmC NC_011751.1 2741125 2743131 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2741125..2743131 Escherichia coli UMN026 7156294 YP_002413374.1 CDS yfcL NC_011751.1 2743252 2743530 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2743252..2743530) Escherichia coli UMN026 7158112 YP_002413375.1 CDS yfcM NC_011751.1 2743564 2744112 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2743564..2744112) Escherichia coli UMN026 7158912 YP_002413376.1 CDS yfcA NC_011751.1 2744112 2744921 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2744112..2744921) Escherichia coli UMN026 7158913 YP_002413377.1 CDS mepA NC_011751.1 2744921 2745745 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2744921..2745745) Escherichia coli UMN026 7158903 YP_002413378.1 CDS aroC NC_011751.1 2745749 2746834 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2745749..2746834) Escherichia coli UMN026 7157099 YP_002413379.1 CDS prmB NC_011751.1 2746869 2747801 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2746869..2747801) Escherichia coli UMN026 7155785 YP_002413380.1 CDS yfcN NC_011751.1 2747967 2748518 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2747967..2748518 Escherichia coli UMN026 7157528 YP_002413381.1 CDS ECUMN_2672 NC_011751.1 2748659 2749522 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2748659..2749522) Escherichia coli UMN026 7158914 YP_002413382.1 CDS ECUMN_2673 NC_011751.1 2749509 2750033 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial protein complement(2749509..2750033) Escherichia coli UMN026 7155153 YP_002413383.1 CDS ECUMN_2674 NC_011751.1 2750030 2750500 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial protein complement(2750030..2750500) Escherichia coli UMN026 7155154 YP_002413384.1 CDS ECUMN_2675 NC_011751.1 2750497 2751111 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative minor fimbrial subunit complement(2750497..2751111) Escherichia coli UMN026 7155155 YP_002413385.1 CDS yfcS NC_011751.1 2751020 2751769 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative periplasmic pilus exported chaperone complement(2751020..2751769) Escherichia coli UMN026 7155156 YP_002413386.1 CDS ECUMN_2677 NC_011751.1 2751789 2754440 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2751789..2754440) Escherichia coli UMN026 7158915 YP_002413387.1 CDS ECUMN_2678 NC_011751.1 2754512 2755078 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2754512..2755078) Escherichia coli UMN026 7155157 YP_002413388.1 CDS sixA NC_011751.1 2755740 2756225 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10089421, 20200300, 9489669; Product type e : enzyme; phosphohistidine phosphatase complement(2755740..2756225) Escherichia coli UMN026 7155158 YP_002413389.1 CDS fadJ NC_011751.1 2756428 2758572 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2756428..2758572) Escherichia coli UMN026 7157933 YP_002413390.1 CDS fadI NC_011751.1 2758572 2759882 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2758572..2759882) Escherichia coli UMN026 7158916 YP_002413391.1 CDS yfcZ NC_011751.1 2760063 2760347 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2760063..2760347) Escherichia coli UMN026 7158917 YP_002413392.1 CDS fadL NC_011751.1 2760713 2762059 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15178802, 2840553, 3286621, 91100327, 1987139, 9119048; Product type t : transporter; long-chain fatty acid outer membrane transporter 2760713..2762059 Escherichia coli UMN026 7158918 YP_002413393.1 CDS yfdF NC_011751.1 2762426 2763673 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2762426..2763673 Escherichia coli UMN026 7156307 YP_002413394.1 CDS vacJ NC_011751.1 2763852 2764607 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8145644, 15352239; Product type lp : lipoprotein; putative lipoprotein complement(2763852..2764607) Escherichia coli UMN026 7158921 YP_002413395.1 CDS ECUMN_2687 NC_011751.1 2764633 2764803 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2764633..2764803) Escherichia coli UMN026 7158209 YP_002413396.1 CDS yfdC NC_011751.1 2764901 2765833 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2764901..2765833 Escherichia coli UMN026 7155159 YP_002413397.1 CDS ECUMN_2689 NC_011751.1 2766193 2766345 D Evidence 6 : Doubtful CDS; hypothetical protein 2766193..2766345 Escherichia coli UMN026 7155578 YP_002413398.1 CDS lacY NC_011751.1 2766425 2767672 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(2766425..2767672) Escherichia coli UMN026 7155160 YP_002413399.1 CDS cscK NC_011751.1 2767734 2768657 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(2767734..2768657) Escherichia coli UMN026 7156021 YP_002413400.1 CDS cscA NC_011751.1 2768864 2770306 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12218016; Product type e : enzyme; Sucrose-6-phosphate hydrolase 2768864..2770306 Escherichia coli UMN026 7156022 YP_002413401.1 CDS cscR NC_011751.1 2770314 2771507 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Sucrose operon repressor complement(2770314..2771507) Escherichia coli UMN026 7156020 YP_002413402.1 CDS dsdA NC_011751.1 2771788 2773119 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2771788..2773119 Escherichia coli UMN026 7156207 YP_002413403.1 CDS emrY NC_011751.1 2773225 2774763 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20378313; Product type pt : putative transporter; putative multidrug efflux system complement(2773225..2774763) Escherichia coli UMN026 7156206 YP_002413404.1 CDS emrK NC_011751.1 2774763 2775926 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20378313; Product type t : transporter; EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component complement(2774763..2775926) Escherichia coli UMN026 7156244 YP_002413405.1 CDS evgA NC_011751.1 2776342 2776956 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2776342..2776956 Escherichia coli UMN026 7156243 YP_002413406.1 CDS evgS NC_011751.1 2776961 2780554 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14523115, 93173621, 9501520, 10923791, 1289796, 8125343, 9535079; Product type r : regulator; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2776961..2780554 Escherichia coli UMN026 7156285 YP_002413407.1 CDS yfdE NC_011751.1 2780609 2781754 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(2780609..2781754) Escherichia coli UMN026 7156286 YP_002413408.1 CDS yfdV NC_011751.1 2781828 2782772 R member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV complement(2781828..2782772) Escherichia coli UMN026 7158920 YP_002413409.1 CDS oxc NC_011751.1 2782841 2784535 R catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase complement(2782841..2784535) Escherichia coli UMN026 7158929 YP_002413410.1 CDS frc NC_011751.1 2784589 2785839 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2784589..2785839) Escherichia coli UMN026 7157369 YP_002413411.1 CDS yfdX NC_011751.1 2786351 2786983 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11157960; hypothetical protein complement(2786351..2786983) Escherichia coli UMN026 7156433 YP_002413412.1 CDS ypdI NC_011751.1 2787279 2787554 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15183873; Product type lp : lipoprotein; putative lipoprotein 2787279..2787554 Escherichia coli UMN026 7158930 YP_002413413.1 CDS yfdY NC_011751.1 2787631 2787873 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089; Product type pm : putative membrane component; hypothetical protein complement(2787631..2787873) Escherichia coli UMN026 7159576 YP_002413415.1 CDS ddg NC_011751.1 2788226 2789146 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2788226..2789146 Escherichia coli UMN026 7155161 YP_002413416.1 CDS yfdZ NC_011751.1 2789638 2790876 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; aminotransferase complement(2789638..2790876) Escherichia coli UMN026 7158100 YP_002413417.1 CDS ypdA NC_011751.1 2791253 2792950 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type prc : putative receptor; putative sensory kinase in two-component system with YpdB 2791253..2792950 Escherichia coli UMN026 7158932 YP_002413418.1 CDS ypdB NC_011751.1 2792965 2793699 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type pr : putative regulator; putative response regulator in two-component system with YpdA 2792965..2793699 Escherichia coli UMN026 7159568 YP_002413419.1 CDS ypdC NC_011751.1 2793712 2794569 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding protein 2793712..2794569 Escherichia coli UMN026 7159569 YP_002413420.1 CDS ypdD NC_011751.1 2794572 2797067 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative fused PTS system Hpr component/enzyme I component/enzyme IIA component complement(2794572..2797067) Escherichia coli UMN026 7159570 YP_002413421.1 CDS ypdE NC_011751.1 2797092 2798129 R metalloprotein; exoaminopeptidase complement(2797092..2798129) Escherichia coli UMN026 7159571 YP_002413422.1 CDS ypdF NC_011751.1 2798129 2799214 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2798129..2799214) Escherichia coli UMN026 7159572 YP_002413423.1 CDS ypdG NC_011751.1 2799229 2800476 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIC component of PTS complement(2799229..2800476) Escherichia coli UMN026 7159573 YP_002413424.1 CDS ypdH NC_011751.1 2800498 2800824 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIB component of PTS complement(2800498..2800824) Escherichia coli UMN026 7159574 YP_002413425.1 CDS glk NC_011751.1 2801044 2802009 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2801044..2802009) Escherichia coli UMN026 7159575 YP_002413426.1 CDS yfeO NC_011751.1 2802213 2803469 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 2802213..2803469 Escherichia coli UMN026 7156543 YP_002413427.1 CDS ypeC NC_011751.1 2803584 2803910 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2803584..2803910 Escherichia coli UMN026 7158939 YP_002413428.1 CDS mntH NC_011751.1 2804052 2805290 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20177822, 20305051, 10712688, 10844693; Product type t : transporter; manganese transport protein MntH complement(2804052..2805290) Escherichia coli UMN026 7159578 YP_002413429.1 CDS nupC NC_011751.1 2805626 2806828 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 374403, 8022285, 7007808, 827549, 4563236, 1512211; Product type t : transporter; nucleoside (except guanosine) transporter 2805626..2806828 Escherichia coli UMN026 7157143 YP_002413430.1 CDS yfeA NC_011751.1 2806878 2809067 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase complement(2806878..2809067) Escherichia coli UMN026 7157336 YP_002413431.1 CDS yfeC NC_011751.1 2809701 2810045 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative nucleic acid-binding transcriptional regulator 2809701..2810045 Escherichia coli UMN026 7155632 YP_002413432.1 CDS yfeD NC_011751.1 2810047 2810439 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative nucleic acid-binding transcriptional regulator 2810047..2810439 Escherichia coli UMN026 7158934 YP_002413433.1 CDS gltX NC_011751.1 2810490 2811905 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2810490..2811905) Escherichia coli UMN026 7158935 YP_002413434.1 CDS ECUMN_2729 NC_011751.1 2812681 2813022 D Evidence 4 : Homologs of previously reported genes of unknown function; putative flxA protein 2812681..2813022 Escherichia coli UMN026 7155582 YP_002413435.1 CDS yfeR NC_011751.1 2813013 2813939 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2813013..2813939) Escherichia coli UMN026 7155162 YP_002413436.1 CDS yfeH NC_011751.1 2814029 2815027 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative sodium/bile acid symporter family protein 2814029..2815027 Escherichia coli UMN026 7158940 YP_002413437.1 CDS ECUMN_2732 NC_011751.1 2815024 2815335 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2815024..2815335) Escherichia coli UMN026 7158937 YP_002413438.1 CDS ligA NC_011751.1 2815244 2817259 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2815244..2817259) Escherichia coli UMN026 7155163 YP_002413439.1 CDS zipA NC_011751.1 2817330 2818316 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2817330..2818316) Escherichia coli UMN026 7156979 YP_002413440.1 CDS cysZ NC_011751.1 2818558 2819319 D putative role in sulfur assimilation; putative sulfate transport protein CysZ 2818558..2819319 Escherichia coli UMN026 7159685 YP_002413441.1 CDS cysK NC_011751.1 2819504 2820475 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2819504..2820475 Escherichia coli UMN026 7156095 YP_002413442.1 CDS ptsH NC_011751.1 2820859 2821116 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 2820859..2821116 Escherichia coli UMN026 7156087 YP_002413443.1 CDS ptsI NC_011751.1 2821161 2822888 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2821161..2822888 Escherichia coli UMN026 7157568 YP_002413444.1 CDS crr NC_011751.1 2822929 2823438 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 2822929..2823438 Escherichia coli UMN026 7157569 YP_002413445.1 CDS pdxK NC_011751.1 2823480 2824331 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2823480..2824331) Escherichia coli UMN026 7156019 YP_002413446.1 CDS yfeK NC_011751.1 2824436 2824804 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2824436..2824804 Escherichia coli UMN026 7157408 YP_002413447.1 CDS cysM NC_011751.1 2824807 2825718 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2824807..2825718) Escherichia coli UMN026 7158938 YP_002413448.1 CDS cysA NC_011751.1 2825852 2826949 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 90264334, 2188958, 7665461; Product type t : transporter; sulfate/thiosulfate transporter subunit complement(2825852..2826949) Escherichia coli UMN026 7156088 YP_002413449.1 CDS cysW NC_011751.1 2826939 2827814 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate permease complement(2826939..2827814) Escherichia coli UMN026 7156078 YP_002413450.1 CDS cysU NC_011751.1 2827814 2828647 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264334, 2188958; Product type t : transporter; sulfate/thiosulfate transporter subunit complement(2827814..2828647) Escherichia coli UMN026 7156094 YP_002413451.1 CDS cysP NC_011751.1 2828647 2829663 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264335, 2188959, 9298646; Product type t : transporter; thiosulfate transporter subunit complement(2828647..2829663) Escherichia coli UMN026 7156093 YP_002413452.1 CDS ucpA NC_011751.1 2829834 2830625 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97385354, 2188959, 7984428, 9241368; Product type pe : putative enzyme; short chain dehydrogenase complement(2829834..2830625) Escherichia coli UMN026 7156090 YP_002413453.1 CDS yfeT NC_011751.1 2830754 2831611 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(2830754..2831611) Escherichia coli UMN026 7158161 YP_002413454.1 CDS murQ NC_011751.1 2831775 2832671 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 2831775..2832671 Escherichia coli UMN026 7158941 YP_002413455.1 CDS murP NC_011751.1 2832675 2834099 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 2832675..2834099 Escherichia coli UMN026 7158942 YP_002413456.1 CDS murQ NC_011751.1 2834017 2835405 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15983044, 15060041; Product type e : enzyme; hypothetical protein 2834017..2835405 Escherichia coli UMN026 7157209 YP_002413457.1 CDS yfeX NC_011751.1 2835463 2836362 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2835463..2836362) Escherichia coli UMN026 7157210 YP_002413458.1 CDS yfeY NC_011751.1 2836458 2837033 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12900013, 7764507; hypothetical protein complement(2836458..2837033) Escherichia coli UMN026 7158943 YP_002413459.1 CDS yfeZ NC_011751.1 2837094 2837543 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2837094..2837543) Escherichia coli UMN026 7158944 YP_002413460.1 CDS ypeA NC_011751.1 2837530 2837955 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase complement(2837530..2837955) Escherichia coli UMN026 7158945 YP_002413461.1 CDS amiA NC_011751.1 2838169 2839038 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 6137479, 87242501, 1903834, 8300522; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase I 2838169..2839038 Escherichia coli UMN026 7159577 YP_002413462.1 CDS hemF NC_011751.1 2839042 2839941 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2839042..2839941 Escherichia coli UMN026 7155733 YP_002413463.1 CDS yfeG NC_011751.1 2839947 2840999 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2839947..2840999) Escherichia coli UMN026 7156655 YP_002413464.1 CDS yffI NC_011751.1 2841045 2841545 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10464203; Product type ps : putative structure; putative ethanolaminosome structural protein complement(2841045..2841545) Escherichia coli UMN026 7158936 YP_002413465.1 CDS eutL NC_011751.1 2841558 2842217 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein complement(2841558..2842217) Escherichia coli UMN026 7158948 YP_002413466.1 CDS eutC NC_011751.1 2842227 2843114 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2842227..2843114) Escherichia coli UMN026 7156281 YP_002413467.1 CDS eutB NC_011751.1 2843135 2844496 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3905806, 10464203; Product type e : enzyme; ethanolamine ammonia-lyase, large subunit, heavy chain complement(2843135..2844496) Escherichia coli UMN026 7156275 YP_002413468.1 CDS eutA NC_011751.1 2844508 2845911 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2844508..2845911) Escherichia coli UMN026 7156274 YP_002413469.1 CDS eutH NC_011751.1 2845908 2847134 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pt : putative transporter; putative ethanolamine transporter complement(2845908..2847134) Escherichia coli UMN026 7156273 YP_002413470.1 CDS eutG NC_011751.1 2847650 2848837 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative alcohol dehydrogenase in ethanolamine utilization; ethanolaminosome complement(2847650..2848837) Escherichia coli UMN026 7156278 YP_002413471.1 CDS eutJ NC_011751.1 2848827 2849663 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pf : putative factor; putative chaperonin, ethanolamine utilization protein complement(2848827..2849663) Escherichia coli UMN026 7156277 YP_002413472.1 CDS eutE NC_011751.1 2849674 2851077 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative aldehyde dehydrogenase, ethanolamine utilization protein complement(2849674..2851077) Escherichia coli UMN026 7156280 YP_002413473.1 CDS cchB NC_011751.1 2851089 2851376 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein complement(2851089..2851376) Escherichia coli UMN026 7156276 YP_002413474.1 CDS cchA NC_011751.1 2851483 2851776 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein complement(2851483..2851776) Escherichia coli UMN026 7155927 YP_002413475.1 CDS eutD NC_011751.1 2851815 2852831 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2851815..2852831) Escherichia coli UMN026 7155926 YP_002413476.1 CDS eutT NC_011751.1 2852828 2853631 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative cobalamin adenosyltransferase complement(2852828..2853631) Escherichia coli UMN026 7156279 YP_002413477.1 CDS eutQ NC_011751.1 2853628 2854329 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10464203; hypothetical protein complement(2853628..2854329) Escherichia coli UMN026 7156284 YP_002413478.1 CDS eutP NC_011751.1 2854304 2854783 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative nucleoside triphosphate hydrolase domain protein complement(2854304..2854783) Escherichia coli UMN026 7156283 YP_002413479.1 CDS ypfE NC_011751.1 2854796 2855131 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein complement(2854796..2855131) Escherichia coli UMN026 7156282 YP_002413480.1 CDS maeB NC_011751.1 2855424 2857703 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2855424..2857703) Escherichia coli UMN026 7159579 YP_002413481.1 CDS talA NC_011751.1 2857992 2858942 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90230300; Product type e : enzyme; transaldolase A 2857992..2858942 Escherichia coli UMN026 7157039 YP_002413482.1 CDS tktB NC_011751.1 2858962 2860965 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2858962..2860965 Escherichia coli UMN026 7158019 YP_002413483.1 CDS ypfG NC_011751.1 2861068 2862111 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2861068..2862111) Escherichia coli UMN026 7158075 YP_002413484.1 CDS yffH NC_011751.1 2862237 2862812 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NUDIX hydrolase complement(2862237..2862812) Escherichia coli UMN026 7159580 YP_002413485.1 CDS aegA NC_011751.1 2862880 2864859 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit complement(2862880..2864859) Escherichia coli UMN026 7158947 YP_002413486.1 CDS narQ NC_011751.1 2865065 2866765 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92374842, 1508040, 1528845; Product type r : regulator; nitrate/nitrite sensor protein NarQ 2865065..2866765 Escherichia coli UMN026 7155705 YP_002413487.1 CDS acrD NC_011751.1 2866929 2870042 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12426336, 20158894, 21450803, 79216220, 10692383, 1644752; Product type t : transporter; aminoglycoside/multidrug efflux system 2866929..2870042 Escherichia coli UMN026 7157254 YP_002413488.1 CDS yffB NC_011751.1 2870581 2870937 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2870581..2870937 Escherichia coli UMN026 7155689 YP_002413489.1 CDS dapE NC_011751.1 2870941 2872068 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2870941..2872068 Escherichia coli UMN026 7158946 YP_002413490.1 CDS ypfN NC_011751.1 2872096 2872296 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2872096..2872296 Escherichia coli UMN026 7156110 YP_002413491.1 CDS ypfH NC_011751.1 2872377 2873075 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH complement(2872377..2873075) Escherichia coli UMN026 7159584 YP_002413492.1 CDS ypfI NC_011751.1 2873149 2875164 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase complement(2873149..2875164) Escherichia coli UMN026 7159581 YP_002413493.1 CDS ypfJ NC_011751.1 2875179 2876042 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2875179..2876042) Escherichia coli UMN026 7159582 YP_002413494.1 CDS purC NC_011751.1 2876210 2876923 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2876210..2876923) Escherichia coli UMN026 7159583 YP_002413495.1 CDS nlpB NC_011751.1 2877136 2878170 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358331, 1885529, 2120198; Product type lp : lipoprotein; lipoprotein complement(2877136..2878170) Escherichia coli UMN026 7157574 YP_002413496.1 CDS dapA NC_011751.1 2878187 2879065 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2878187..2879065) Escherichia coli UMN026 7157286 YP_002413497.1 CDS gcvR NC_011751.1 2879211 2879783 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2879211..2879783 Escherichia coli UMN026 7156107 YP_002413498.1 CDS bcp NC_011751.1 2879783 2880253 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2879783..2880253 Escherichia coli UMN026 7156524 YP_002413499.1 CDS hyfA NC_011751.1 2880506 2881123 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241, 2016588; Product type c : carrier; hydrogenase 4, 4Fe-4S subunit 2880506..2881123 Escherichia coli UMN026 7155855 YP_002413500.1 CDS hyfB NC_011751.1 2881123 2883141 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit B 2881123..2883141 Escherichia coli UMN026 7156758 YP_002413501.1 CDS hyfC NC_011751.1 2883152 2884099 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4, membrane subunit 2883152..2884099 Escherichia coli UMN026 7156759 YP_002413502.1 CDS hyfD NC_011751.1 2884116 2885555 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit D 2884116..2885555 Escherichia coli UMN026 7156760 YP_002413503.1 CDS hyfE NC_011751.1 2885567 2886217 D interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2885567..2886217 Escherichia coli UMN026 7156761 YP_002413504.1 CDS hyfF NC_011751.1 2886222 2887802 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit F 2886222..2887802 Escherichia coli UMN026 7156762 YP_002413505.1 CDS hyfG NC_011751.1 2887840 2889507 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4, subunit 2887840..2889507 Escherichia coli UMN026 7156763 YP_002413506.1 CDS hyfH NC_011751.1 2889517 2890062 D probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2889517..2890062 Escherichia coli UMN026 7156764 YP_002413507.1 CDS hyfI NC_011751.1 2890059 2890817 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4, Fe-S subunit 2890059..2890817 Escherichia coli UMN026 7156765 YP_002413508.1 CDS hyfJ NC_011751.1 2890810 2891223 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9387241; Product type pf : putative factor; putative processing element hydrogenase 4 2890810..2891223 Escherichia coli UMN026 7156766 YP_002413509.1 CDS hyfR NC_011751.1 2891253 2893265 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type r : regulator; DNA-binding transcriptional activator, formate sensing 2891253..2893265 Escherichia coli UMN026 7156767 YP_002413510.1 CDS focB NC_011751.1 2893287 2894135 D inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter 2893287..2894135 Escherichia coli UMN026 7156768 YP_002413511.1 CDS perM NC_011751.1 2894172 2895233 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease complement(2894172..2895233) Escherichia coli UMN026 7156422 YP_002413512.1 CDS yfgC NC_011751.1 2895446 2896909 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 2895446..2896909 Escherichia coli UMN026 7157418 YP_002413513.1 CDS yfgD NC_011751.1 2896930 2897289 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 2896930..2897289 Escherichia coli UMN026 7158951 YP_002413514.1 CDS hda NC_011751.1 2897395 2898141 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2897395..2898141) Escherichia coli UMN026 7158952 YP_002413515.1 CDS uraA NC_011751.1 2898191 2899480 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 7721693; Product type t : transporter; uracil transporter complement(2898191..2899480) Escherichia coli UMN026 7156643 YP_002413516.1 CDS upp NC_011751.1 2899566 2900192 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2899566..2900192) Escherichia coli UMN026 7158190 YP_002413517.1 CDS purM NC_011751.1 2900517 2901554 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2900517..2901554 Escherichia coli UMN026 7158189 YP_002413518.1 CDS purN NC_011751.1 2901554 2902192 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2901554..2902192 Escherichia coli UMN026 7157581 YP_002413519.1 CDS ppk NC_011751.1 2902364 2904430 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2902364..2904430 Escherichia coli UMN026 7157582 YP_002413520.1 CDS ppx NC_011751.1 2904435 2905976 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93107072, 94025037, 94165003, 8212131, 8380170; Product type e : enzyme; exopolyphosphatase 2904435..2905976 Escherichia coli UMN026 7157509 YP_002413521.1 CDS yfgF NC_011751.1 2906015 2908258 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2906015..2908258) Escherichia coli UMN026 7157512 YP_002413522.1 CDS ECUMN_2818 NC_011751.1 2908475 2908765 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2908475..2908765) Escherichia coli UMN026 7158953 YP_002413523.1 CDS yfgH NC_011751.1 2909112 2909630 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane lipoprotein 2909112..2909630 Escherichia coli UMN026 7155164 YP_002413524.1 CDS yfgI NC_011751.1 2909646 2910185 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2909646..2910185 Escherichia coli UMN026 7158954 YP_002413525.1 CDS ECUMN_2821 NC_011751.1 2910333 2910842 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group complement(2910333..2910842) Escherichia coli UMN026 7158955 YP_002413526.1 CDS ECUMN_2822 NC_011751.1 2910748 2910936 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2910748..2910936) Escherichia coli UMN026 7155165 YP_002413527.1 CDS guaA NC_011751.1 2910989 2912566 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2910989..2912566) Escherichia coli UMN026 7155166 YP_002413528.1 CDS guaB NC_011751.1 2912635 2914101 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2912635..2914101) Escherichia coli UMN026 7156622 YP_002413529.1 CDS xseA NC_011751.1 2914263 2915639 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2914263..2915639 Escherichia coli UMN026 7156623 YP_002413530.1 CDS ECUMN_2828 NC_011751.1 2923862 2924839 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12540539; Product type pm : putative membrane component; putative outer membrane protein (sivI-like) complement(2923862..2924839) Escherichia coli UMN026 7155168 YP_002413531.1 CDS ECUMN_2829 NC_011751.1 2924894 2927101 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8500884, 3304658, 12540539; Product type pf : putative factor; putative intimin complement(2924894..2927101) Escherichia coli UMN026 7155169 YP_002413532.1 CDS ECUMN_2830 NC_011751.1 2927281 2927496 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2927281..2927496) Escherichia coli UMN026 7155170 YP_002413533.1 CDS engA NC_011751.1 2927559 2929031 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2927559..2929031) Escherichia coli UMN026 7155171 YP_002413534.1 CDS yfgL NC_011751.1 2929149 2930327 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2929149..2930327) Escherichia coli UMN026 7156146 YP_002413535.1 CDS yfgM NC_011751.1 2930338 2930958 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2930338..2930958) Escherichia coli UMN026 7158956 YP_002413536.1 CDS hisS NC_011751.1 2930976 2932250 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2930976..2932250) Escherichia coli UMN026 7158957 YP_002413537.1 CDS ispG NC_011751.1 2932361 2933479 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2932361..2933479) Escherichia coli UMN026 7156686 YP_002413538.1 CDS yfgA NC_011751.1 2933506 2934519 R Evidence 4 : Homologs of previously reported genes of unknown function; cytoskeletal protein RodZ complement(2933506..2934519) Escherichia coli UMN026 7156867 YP_002413539.1 CDS yfgB NC_011751.1 2934804 2935958 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2934804..2935958) Escherichia coli UMN026 7158949 YP_002413540.1 CDS ndk NC_011751.1 2936108 2936539 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2936108..2936539) Escherichia coli UMN026 7158950 YP_002413541.1 CDS pbpC NC_011751.1 2936688 2939000 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2936688..2939000) Escherichia coli UMN026 7157262 YP_002413542.1 CDS yfhM NC_011751.1 2939001 2943962 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2939001..2943962) Escherichia coli UMN026 7157394 YP_002413543.1 CDS sseA NC_011751.1 2944169 2945014 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2944169..2945014 Escherichia coli UMN026 7158966 YP_002413544.1 CDS sseB NC_011751.1 2945774 2946550 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2945774..2946550) Escherichia coli UMN026 7157844 YP_002413545.1 CDS pepB NC_011751.1 2946692 2947975 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B complement(2946692..2947975) Escherichia coli UMN026 7157984 YP_002413546.1 CDS yfhJ NC_011751.1 2948220 2948420 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10393315; Product type pf : putative factor; hypothetical protein complement(2948220..2948420) Escherichia coli UMN026 7157411 YP_002413547.1 CDS fdx NC_011751.1 2948432 2948767 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 20013001, 92283811, 94181532, 11551196, 1317854, 4375562, 8300516; Product type c : carrier; [2Fe-2S] ferredoxin complement(2948432..2948767) Escherichia coli UMN026 7158963 YP_002413548.1 CDS hscA NC_011751.1 2948769 2950619 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2948769..2950619) Escherichia coli UMN026 7156323 YP_002413549.1 CDS hscB NC_011751.1 2950636 2951151 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2950636..2951151) Escherichia coli UMN026 7156714 YP_002413550.1 CDS iscA NC_011751.1 2951247 2951570 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2951247..2951570) Escherichia coli UMN026 7156715 YP_002413551.1 CDS iscU NC_011751.1 2951587 2951973 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 11994302, 15153099; Product type f : factor; scaffold protein complement(2951587..2951973) Escherichia coli UMN026 7156857 YP_002413552.1 CDS iscS NC_011751.1 2952001 2953215 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2952001..2953215) Escherichia coli UMN026 7156860 YP_002413553.1 CDS iscR NC_011751.1 2953327 2953815 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2953327..2953815) Escherichia coli UMN026 7156859 YP_002413554.1 CDS yfhQ NC_011751.1 2954085 2954825 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10393315; Product type pe : putative enzyme; putative methyltransferase complement(2954085..2954825) Escherichia coli UMN026 7156858 YP_002413555.1 CDS suhB NC_011751.1 2954944 2955747 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6389495, 90202735, 95095968, 10747806, 2138605, 8002619; Product type e : enzyme; inositol monophosphatase 2954944..2955747 Escherichia coli UMN026 7158967 YP_002413556.1 CDS yfhR NC_011751.1 2955892 2956746 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 2955892..2956746 Escherichia coli UMN026 7158010 YP_002413557.1 CDS csiE NC_011751.1 2956937 2958217 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95020540, 96154950; Product type cp : cell process; stationary phase inducible protein CsiE 2956937..2958217 Escherichia coli UMN026 7158968 YP_002413558.1 CDS hcaT NC_011751.1 2958209 2959348 R putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter complement(2958209..2959348) Escherichia coli UMN026 7156032 YP_002413559.1 CDS hcaR NC_011751.1 2959508 2960398 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR complement(2959508..2960398) Escherichia coli UMN026 7156639 YP_002413560.1 CDS hcaE NC_011751.1 2960534 2961895 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83238171, 87008429, 98269008; Product type e : enzyme; 3-phenylpropionate dioxygenase, large subunit alpha 2960534..2961895 Escherichia coli UMN026 7156638 YP_002413561.1 CDS hcaF NC_011751.1 2961892 2962410 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83238171, 87008429, 98269008, 9603882; Product type e : enzyme; 3-phenylpropionate dioxygenase subunit beta 2961892..2962410 Escherichia coli UMN026 7156636 YP_002413562.1 CDS hcaC NC_011751.1 2962410 2962730 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98269008, 9603882; Product type pc : putative carrier; 3-phenylpropionate dioxygenase ferredoxin subunit 2962410..2962730 Escherichia coli UMN026 7156637 YP_002413563.1 CDS hcaB NC_011751.1 2962727 2963539 D Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2962727..2963539 Escherichia coli UMN026 7156634 YP_002413564.1 CDS hcaD NC_011751.1 2963549 2964751 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98269008, 9603882; Product type e : enzyme; phenylpropionate dioxygenase ferredoxin reductase subunit 2963549..2964751 Escherichia coli UMN026 7156633 YP_002413565.1 CDS yphA NC_011751.1 2964803 2965270 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2964803..2965270 Escherichia coli UMN026 7156635 YP_002413566.1 CDS yphB NC_011751.1 2965317 2966189 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2965317..2966189) Escherichia coli UMN026 7159585 YP_002413567.1 CDS yphC NC_011751.1 2966201 2967262 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(2966201..2967262) Escherichia coli UMN026 7159586 YP_002413568.1 CDS yphD NC_011751.1 2967328 2968326 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter membrane protein complement(2967328..2968326) Escherichia coli UMN026 7159587 YP_002413569.1 CDS yphE NC_011751.1 2968351 2969862 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter ATP-binding protein complement(2968351..2969862) Escherichia coli UMN026 7159588 YP_002413570.1 CDS yphF NC_011751.1 2969885 2970868 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter; putative sugar ABC transporter periplasmic-binding protein complement(2969885..2970868) Escherichia coli UMN026 7159589 YP_002413571.1 CDS yphG NC_011751.1 2970965 2974246 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2970965..2974246) Escherichia coli UMN026 7159590 YP_002413572.1 CDS yphH NC_011751.1 2974364 2975557 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2974364..2975557 Escherichia coli UMN026 7159591 YP_002413573.1 CDS glyA NC_011751.1 2975755 2977008 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2975755..2977008) Escherichia coli UMN026 7159592 YP_002413574.1 CDS hmp NC_011751.1 2977337 2978527 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2977337..2978527 Escherichia coli UMN026 7156585 YP_002413575.1 CDS glnB NC_011751.1 2978572 2978910 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2978572..2978910) Escherichia coli UMN026 7156689 YP_002413576.1 CDS yfhA NC_011751.1 2978971 2980305 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226691, 8412694; Product type pr : putative regulator; putative DNA-binding response regulator in two-component system complement(2978971..2980305) Escherichia coli UMN026 7156549 YP_002413577.1 CDS yfhG NC_011751.1 2980295 2981008 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2980295..2981008) Escherichia coli UMN026 7158958 YP_002413578.1 CDS yfhK NC_011751.1 2981173 2982600 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensory kinase in two-component system complement(2981173..2982600) Escherichia coli UMN026 7158961 YP_002413579.1 CDS purL NC_011751.1 2983176 2987063 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2983176..2987063) Escherichia coli UMN026 7158073 YP_002413580.1 CDS yfhD NC_011751.1 2987459 2988877 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 2987459..2988877 Escherichia coli UMN026 7157580 YP_002413581.1 CDS tadA NC_011751.1 2988874 2989410 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12110595; Product type e : enzyme; tRNA -specific adenosine deaminase complement(2988874..2989410) Escherichia coli UMN026 7158960 YP_002413582.1 CDS yfhB NC_011751.1 2989435 2990070 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2989435..2990070) Escherichia coli UMN026 7158017 YP_002413583.1 CDS yfhH NC_011751.1 2990279 2991127 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2990279..2991127 Escherichia coli UMN026 7158959 YP_002413584.1 CDS yfhL NC_011751.1 2991183 2991443 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8765743, 8880900; Product type c : carrier; ferredoxin 2991183..2991443 Escherichia coli UMN026 7158962 YP_002413585.1 CDS ECUMN_2883 NC_011751.1 2991715 2991879 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2991715..2991879) Escherichia coli UMN026 7157845 YP_002413586.1 CDS acpS NC_011751.1 2992138 2992518 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2992138..2992518) Escherichia coli UMN026 7157846 YP_002413587.1 CDS pdxJ NC_011751.1 2992518 2993249 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2992518..2993249) Escherichia coli UMN026 7155685 YP_002413588.1 CDS recO NC_011751.1 2993261 2993989 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2993261..2993989) Escherichia coli UMN026 7157407 YP_002413589.1 CDS era NC_011751.1 2994001 2994906 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2994001..2994906) Escherichia coli UMN026 7157645 YP_002413590.1 CDS rnc NC_011751.1 2994903 2995583 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2994903..2995583) Escherichia coli UMN026 7156267 YP_002413591.1 CDS lepB NC_011751.1 2995856 2996830 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2995856..2996830) Escherichia coli UMN026 7157708 YP_002413592.1 CDS lepA NC_011751.1 2996846 2998645 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2996846..2998645) Escherichia coli UMN026 7156941 YP_002413593.1 CDS rseC NC_011751.1 2998843 2999322 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2998843..2999322) Escherichia coli UMN026 7156940 YP_002413594.1 CDS rseB NC_011751.1 2999319 3000275 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2999319..3000275) Escherichia coli UMN026 7157794 YP_002413595.1 CDS rseA NC_011751.1 3000275 3000925 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9159522, 97303092, 99431977, 7768826; Product type f : factor; anti-RNA polymerase sigma factor SigE complement(3000275..3000925) Escherichia coli UMN026 7157793 YP_002413596.1 CDS rpoE NC_011751.1 3000958 3001533 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(3000958..3001533) Escherichia coli UMN026 7157792 YP_002413597.1 CDS yfiC NC_011751.1 3003549 3004286 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase complement(3003549..3004286) Escherichia coli UMN026 7157222 YP_002413598.1 CDS srmB NC_011751.1 3004418 3005752 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 3004418..3005752 Escherichia coli UMN026 7158971 YP_002413599.1 CDS ECUMN_2900 NC_011751.1 3005931 3006461 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 3005931..3006461 Escherichia coli UMN026 7157979 YP_002413600.1 CDS ECUMN_2901 NC_011751.1 3006566 3007288 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 3006566..3007288 Escherichia coli UMN026 7155173 YP_002413601.1 CDS yfiE NC_011751.1 3007397 3008278 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3007397..3008278) Escherichia coli UMN026 7155174 YP_002413602.1 CDS yfiK NC_011751.1 3008381 3008968 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12562784; Product type t : transporter; neutral amino-acid efflux protein 3008381..3008968 Escherichia coli UMN026 7158973 YP_002413603.1 CDS yfiD NC_011751.1 3009022 3009405 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(3009022..3009405) Escherichia coli UMN026 7158976 YP_002413604.1 CDS ung NC_011751.1 3009710 3010399 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3009710..3010399 Escherichia coli UMN026 7158972 YP_002413605.1 CDS yfiF NC_011751.1 3010447 3011484 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase complement(3010447..3011484) Escherichia coli UMN026 7158188 YP_002413606.1 CDS ECUMN_2907 NC_011751.1 3011474 3011677 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3011474..3011677) Escherichia coli UMN026 7158974 YP_002413607.1 CDS trxC NC_011751.1 3011691 3012110 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12952960, 9388228, 99175138, 10644706; Product type c : carrier; thioredoxin 2 3011691..3012110 Escherichia coli UMN026 7155175 YP_002413608.1 CDS yfiP NC_011751.1 3012179 3012877 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3012179..3012877 Escherichia coli UMN026 7158131 YP_002413609.1 CDS yfiQ NC_011751.1 3012909 3015569 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acyl-CoA synthetase NAD(P)-binding/ATP-binding subunit 3012909..3015569 Escherichia coli UMN026 7158981 YP_002413610.1 CDS pssA NC_011751.1 3015683 3017038 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 3015683..3017038 Escherichia coli UMN026 7158982 YP_002413611.1 CDS yfiM NC_011751.1 3017063 3017407 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3017063..3017407 Escherichia coli UMN026 7157556 YP_002413612.1 CDS kgtP NC_011751.1 3017404 3018702 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91219460, 1709493, 2053984, 2118499, 2190187, 8419306; Product type t : transporter; alpha-ketoglutarate transporter complement(3017404..3018702) Escherichia coli UMN026 7158978 YP_002413613.1 CDS clpB NC_011751.1 3024508 3027081 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor; protein disaggregation chaperone complement(3024508..3027081) Escherichia coli UMN026 7154984 YP_002413614.1 CDS yfiH NC_011751.1 3027211 3027942 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1906060, 2066329; hypothetical protein complement(3027211..3027942) Escherichia coli UMN026 7157847 YP_002413615.1 CDS rluD NC_011751.1 3027939 3028919 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(3027939..3028919) Escherichia coli UMN026 7158975 YP_002413616.1 CDS yfiO NC_011751.1 3029054 3029791 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 3029054..3029791 Escherichia coli UMN026 7157702 YP_002413617.1 CDS yfiA NC_011751.1 3030062 3030403 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 3030062..3030403 Escherichia coli UMN026 7158980 YP_002413619.1 CDS pheA NC_011751.1 3030653 3031813 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3030653..3031813 Escherichia coli UMN026 7157434 YP_002413620.1 CDS tyrA NC_011751.1 3031856 3032977 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(3031856..3032977) Escherichia coli UMN026 7157433 YP_002413621.1 CDS aroF NC_011751.1 3032988 3034058 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3032988..3034058) Escherichia coli UMN026 7158147 YP_002413622.1 CDS yfiL NC_011751.1 3034267 3034632 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6396419; hypothetical protein 3034267..3034632 Escherichia coli UMN026 7155788 YP_002413623.1 CDS yfiR NC_011751.1 3034779 3035297 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3034779..3035297 Escherichia coli UMN026 7158977 YP_002413624.1 CDS yfiN NC_011751.1 3035287 3036513 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; hypothetical protein 3035287..3036513 Escherichia coli UMN026 7158983 YP_002413625.1 CDS yfiB NC_011751.1 3036529 3037011 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96032391; Product type pm : putative membrane component; putative outer membrane lipoprotein 3036529..3037011 Escherichia coli UMN026 7158979 YP_002413626.1 CDS rplS NC_011751.1 3037087 3037434 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(3037087..3037434) Escherichia coli UMN026 7158970 YP_002413627.1 CDS trmD NC_011751.1 3037476 3038243 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(3037476..3038243) Escherichia coli UMN026 7157741 YP_002413628.1 CDS rimM NC_011751.1 3038274 3038822 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(3038274..3038822) Escherichia coli UMN026 7158113 YP_002413629.1 CDS rpsP NC_011751.1 3038841 3039089 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(3038841..3039089) Escherichia coli UMN026 7157695 YP_002413630.1 CDS ffh NC_011751.1 3039338 3040699 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(3039338..3040699) Escherichia coli UMN026 7157782 YP_002413631.1 CDS ypjD NC_011751.1 3040791 3041657 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3040791..3041657 Escherichia coli UMN026 7156340 YP_002413632.1 CDS yfjD NC_011751.1 3041768 3042964 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3041768..3042964 Escherichia coli UMN026 7159594 YP_002413633.1 CDS grpE NC_011751.1 3043019 3043612 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(3043019..3043612) Escherichia coli UMN026 7158985 YP_002413634.1 CDS ppnK NC_011751.1 3043735 3044613 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3043735..3044613 Escherichia coli UMN026 7156613 YP_002413635.1 CDS recN NC_011751.1 3044699 3046360 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87259985, 91355307, 95058623, 3037486; Product type cp : cell process; recombination and repair protein 3044699..3046360 Escherichia coli UMN026 7158984 YP_002413636.1 CDS smpA NC_011751.1 3046509 3046850 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2045357; Product type lp : lipoprotein; hypothetical protein 3046509..3046850 Escherichia coli UMN026 7157644 YP_002413637.1 CDS yfjF NC_011751.1 3046912 3047202 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3046912..3047202) Escherichia coli UMN026 7157942 YP_002413638.1 CDS yfjG NC_011751.1 3047192 3047668 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3047192..3047668) Escherichia coli UMN026 7158986 YP_002413639.1 CDS smpB NC_011751.1 3047800 3048282 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3047800..3048282 Escherichia coli UMN026 7158987 YP_002413640.1 CDS ECUMN_2945 NC_011751.1 3049026 3050273 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; prophage CP4-57 integrase 3049026..3050273 Escherichia coli UMN026 7157988 YP_002413641.1 CDS ECUMN_2946 NC_011751.1 3050320 3050919 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3050320..3050919 Escherichia coli UMN026 7155176 YP_002413642.1 CDS ECUMN_2947 NC_011751.1 3051269 3052441 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(3051269..3052441) Escherichia coli UMN026 7155177 YP_002413643.1 CDS ECUMN_2948 NC_011751.1 3052815 3053432 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3052815..3053432 Escherichia coli UMN026 7155178 YP_002413644.1 CDS ECUMN_2949 NC_011751.1 3053407 3054033 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 3053407..3054033 Escherichia coli UMN026 7155179 YP_002413645.1 CDS ECUMN_2951 NC_011751.1 3054619 3056688 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3054619..3056688 Escherichia coli UMN026 7155180 YP_002413646.1 CDS ECUMN_2952 NC_011751.1 3057361 3058347 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3057361..3058347 Escherichia coli UMN026 7155181 YP_002413647.1 CDS ECUMN_2953 NC_011751.1 3058340 3059563 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 3058340..3059563 Escherichia coli UMN026 7155182 YP_002413648.1 CDS ECUMN_2954 NC_011751.1 3059590 3059805 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 3059590..3059805 Escherichia coli UMN026 7155183 YP_002413649.1 CDS ECUMN_2955 NC_011751.1 3059798 3061000 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; putative ERCC4-like helicase 3059798..3061000 Escherichia coli UMN026 7155184 YP_002413650.1 CDS ECUMN_2956 NC_011751.1 3061039 3062322 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; putative Signal transduction histidine kinase 3061039..3062322 Escherichia coli UMN026 7155185 YP_002413651.1 CDS ECUMN_2957 NC_011751.1 3062477 3062956 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(3062477..3062956) Escherichia coli UMN026 7155186 YP_002413652.1 CDS ECUMN_2958 NC_011751.1 3063317 3063838 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; glucitol/sorbitol permease IIC component from bacteriophage origin 3063317..3063838 Escherichia coli UMN026 7155187 YP_002413653.1 CDS ECUMN_2959 NC_011751.1 3063988 3064209 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glucitol/sorbitol-specific phosphotransferase enzyme IIA component 3063988..3064209 Escherichia coli UMN026 7155188 YP_002413654.1 CDS srlE NC_011751.1 3064206 3065186 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9435786; Product type m : membrane component; glucitol/sorbitol-specific phosphotransferase enzyme IIB component 3064206..3065186 Escherichia coli UMN026 7155189 YP_002413655.1 CDS ECUMN_2961 NC_011751.1 3065197 3066210 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative dehydrogenase from bacteriophage origin 3065197..3066210 Escherichia coli UMN026 7157976 YP_002413656.1 CDS ECUMN_2962 NC_011751.1 3066453 3067706 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3066453..3067706 Escherichia coli UMN026 7155190 YP_002413657.1 CDS ECUMN_2963 NC_011751.1 3067778 3068413 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10572115; Product type pe : putative enzyme; putative 3-hexulose-6-phosphate synthase from bacteriophage origin complement(3067778..3068413) Escherichia coli UMN026 7155191 YP_002413658.1 CDS ECUMN_2964 NC_011751.1 3068437 3069003 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10572115; Product type pe : putative enzyme; putative 3-hexulose-6-phosphate isomerase (PHI) from bacteriophage origin complement(3068437..3069003) Escherichia coli UMN026 7155192 YP_002413659.1 CDS ECUMN_2965 NC_011751.1 3069000 3069842 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Glucose-6-phosphate isomerase from bacteriophage origin complement(3069000..3069842) Escherichia coli UMN026 7155193 YP_002413660.1 CDS ptsG NC_011751.1 3069839 3071365 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; PTS system glucose-specific EIIABC component from bacteriophage origin complement(3069839..3071365) Escherichia coli UMN026 7155194 YP_002413661.1 CDS ECUMN_2967 NC_011751.1 3071573 3073267 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic component from bacteriophage origin 3071573..3073267 Escherichia coli UMN026 7157567 YP_002413662.1 CDS ECUMN_2968 NC_011751.1 3073619 3074158 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Bifunctional deaminase-reductase complement(3073619..3074158) Escherichia coli UMN026 7155195 YP_002413663.1 CDS ECUMN_2969 NC_011751.1 3074332 3075402 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3074332..3075402 Escherichia coli UMN026 7155196 YP_002413664.1 CDS ECUMN_2970 NC_011751.1 3075474 3075698 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3075474..3075698) Escherichia coli UMN026 7155197 YP_002413665.1 CDS ECUMN_2971 NC_011751.1 3075733 3076830 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3075733..3076830) Escherichia coli UMN026 7155198 YP_002413666.1 CDS ECUMN_2972 NC_011751.1 3077184 3077864 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; site-specific recombinase, phage integrase family complement(3077184..3077864) Escherichia coli UMN026 7155199 YP_002413667.1 CDS ECUMN_2973 NC_011751.1 3078096 3078722 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3078096..3078722 Escherichia coli UMN026 7155200 YP_002413668.1 CDS ECUMN_2974 NC_011751.1 3078747 3079022 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3078747..3079022 Escherichia coli UMN026 7155201 YP_002413669.1 CDS ECUMN_2975 NC_011751.1 3079355 3079693 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3079355..3079693) Escherichia coli UMN026 7155202 YP_002413670.1 CDS ypjA NC_011751.1 3080198 3084901 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type t : transporter; adhesin-like autotransporter complement(3080198..3084901) Escherichia coli UMN026 7155203 YP_002413671.1 CDS ECUMN_2978 NC_011751.1 3085706 3087160 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3085706..3087160) Escherichia coli UMN026 7157466 YP_002413672.1 CDS ECUMN_2979 NC_011751.1 3087481 3087657 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3087481..3087657) Escherichia coli UMN026 7155204 YP_002413673.1 CDS insH NC_011751.1 3087517 3088533 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage 3087517..3088533 Escherichia coli UMN026 7155205 YP_002413674.1 CDS ECUMN_2981 NC_011751.1 3089012 3089209 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3089012..3089209) Escherichia coli UMN026 7156832 YP_002413675.1 CDS ECUMN_2982 NC_011751.1 3089751 3092003 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Alpha-amylase 3089751..3092003 Escherichia coli UMN026 7155629 YP_002413676.1 CDS ygaT NC_011751.1 3092339 3093316 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3092339..3093316 Escherichia coli UMN026 7155207 YP_002413677.1 CDS ygaF NC_011751.1 3093336 3094604 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3093336..3094604 Escherichia coli UMN026 7158994 YP_002413678.1 CDS gabD NC_011751.1 3094627 3096075 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3094627..3096075 Escherichia coli UMN026 7158990 YP_002413679.1 CDS gabT NC_011751.1 3096089 3097369 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3096089..3097369 Escherichia coli UMN026 7156483 YP_002413680.1 CDS gabP NC_011751.1 3097680 3099080 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94127927, 9685361, 8297211; Product type t : transporter; gamma-aminobutyrate transporter 3097680..3099080 Escherichia coli UMN026 7156485 YP_002413681.1 CDS csiR NC_011751.1 3099101 3099763 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3099101..3099763 Escherichia coli UMN026 7156484 YP_002413682.1 CDS ygaU NC_011751.1 3099764 3100213 R Evidence 4 : Homologs of previously reported genes of unknown function; LysM domain/BON superfamily protein complement(3099764..3100213) Escherichia coli UMN026 7156033 YP_002413683.1 CDS yqaE NC_011751.1 3100297 3100455 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3100297..3100455) Escherichia coli UMN026 7158995 YP_002413684.1 CDS ygaV NC_011751.1 3100638 3100937 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3100638..3100937 Escherichia coli UMN026 7159597 YP_002413685.1 CDS ygaP NC_011751.1 3100947 3101471 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme; hypothetical protein 3100947..3101471 Escherichia coli UMN026 7158996 YP_002413686.1 CDS stpA NC_011751.1 3101518 3101922 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20485613, 93126121, 9643551, 98132400, 99415935, 1480493, 7961433; Product type r : regulator; DNA binding protein, nucleoid-associated complement(3101518..3101922) Escherichia coli UMN026 7158993 YP_002413687.1 CDS ygaW NC_011751.1 3102590 3103039 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3102590..3103039 Escherichia coli UMN026 7157997 YP_002413688.1 CDS ygaC NC_011751.1 3103076 3103420 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7961433; hypothetical protein complement(3103076..3103420) Escherichia coli UMN026 7158997 YP_002413689.1 CDS ygaM NC_011751.1 3103560 3103901 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3103560..3103901 Escherichia coli UMN026 7158988 YP_002413690.1 CDS ECUMN_2997 NC_011751.1 3103958 3105292 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative fused protein: aminotransaminase/transcriptional regulator, GntR family complement(3103958..3105292) Escherichia coli UMN026 7158992 YP_002413691.1 CDS ECUMN_2998 NC_011751.1 3105380 3105811 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3105380..3105811 Escherichia coli UMN026 7155208 YP_002413692.1 CDS nrdH NC_011751.1 3106020 3106265 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9218434, 11441020, 8820648; Product type pc : putative carrier; glutaredoxin-like protein 3106020..3106265 Escherichia coli UMN026 7155209 YP_002413693.1 CDS nrdI NC_011751.1 3106262 3106663 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3106262..3106663 Escherichia coli UMN026 7157304 YP_002413694.1 CDS nrdE NC_011751.1 3106645 3108789 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3106645..3108789 Escherichia coli UMN026 7157305 YP_002413695.1 CDS nrdF NC_011751.1 3108799 3109758 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3108799..3109758 Escherichia coli UMN026 7157301 YP_002413696.1 CDS proV NC_011751.1 3110115 3111317 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3110115..3111317 Escherichia coli UMN026 7157302 YP_002413697.1 CDS proW NC_011751.1 3111310 3112374 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3111310..3112374 Escherichia coli UMN026 7157536 YP_002413698.1 CDS proX NC_011751.1 3112431 3113423 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3112431..3113423 Escherichia coli UMN026 7157537 YP_002413699.1 CDS ECUMN_3006 NC_011751.1 3113876 3115060 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16000740; Product type pt : putative transporter; putative transport protein 3113876..3115060 Escherichia coli UMN026 7157538 YP_002413700.1 CDS ygaZ NC_011751.1 3115184 3115921 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3115184..3115921 Escherichia coli UMN026 7155210 YP_002413701.1 CDS ygaH NC_011751.1 3115911 3116246 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3115911..3116246 Escherichia coli UMN026 7158998 YP_002413702.1 CDS mprA NC_011751.1 3116337 3116867 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3116337..3116867 Escherichia coli UMN026 7158991 YP_002413703.1 CDS emrA NC_011751.1 3116994 3118166 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590, 8203018; Product type t : transporter; multidrug efflux system 3116994..3118166 Escherichia coli UMN026 7157169 YP_002413704.1 CDS emrB NC_011751.1 3118183 3119721 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590; Product type t : transporter; multidrug efflux system protein 3118183..3119721 Escherichia coli UMN026 7156240 YP_002413705.1 CDS luxS NC_011751.1 3119785 3120300 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(3119785..3120300) Escherichia coli UMN026 7156241 YP_002413706.1 CDS gshA NC_011751.1 3120450 3122006 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(3120450..3122006) Escherichia coli UMN026 7157130 YP_002413707.1 CDS yqaA NC_011751.1 3122079 3122507 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3122079..3122507) Escherichia coli UMN026 7156617 YP_002413708.1 CDS yqaB NC_011751.1 3122504 3123070 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(3122504..3123070) Escherichia coli UMN026 7159595 YP_002413709.1 CDS csrA NC_011751.1 3124662 3124847 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(3124662..3124847) Escherichia coli UMN026 7155624 YP_002413710.1 CDS alaS NC_011751.1 3125082 3127712 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(3125082..3127712) Escherichia coli UMN026 7156043 YP_002413711.1 CDS recX NC_011751.1 3127840 3128340 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(3127840..3128340) Escherichia coli UMN026 7155721 YP_002413712.1 CDS recA NC_011751.1 3128409 3129470 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(3128409..3129470) Escherichia coli UMN026 7157648 YP_002413713.1 CDS ygaD NC_011751.1 3129550 3130047 R Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A complement(3129550..3130047) Escherichia coli UMN026 7157637 YP_002413714.1 CDS mltB NC_011751.1 3130192 3131277 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(3130192..3131277) Escherichia coli UMN026 7158989 YP_002413715.1 CDS srlA NC_011751.1 3131533 3132096 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87194727, 1334233, 3553176; Product type t : transporter; glucitol/sorbitol-specific enzyme IIC component of PTS 3131533..3132096 Escherichia coli UMN026 7157140 YP_002413716.1 CDS srlE NC_011751.1 3132093 3133052 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1100602, 3553176; Product type t : transporter; glucitol/sorbitol-specific enzyme IIB component of PTS 3132093..3133052 Escherichia coli UMN026 7157973 YP_002413717.1 CDS srlB NC_011751.1 3133063 3133434 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3133063..3133434 Escherichia coli UMN026 7157977 YP_002413718.1 CDS srlD NC_011751.1 3133438 3134217 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3133438..3134217 Escherichia coli UMN026 7157974 YP_002413719.1 CDS gutM NC_011751.1 3134323 3134682 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3134323..3134682 Escherichia coli UMN026 7157975 YP_002413720.1 CDS srlR NC_011751.1 3134749 3135522 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3134749..3135522 Escherichia coli UMN026 7156629 YP_002413721.1 CDS gutQ NC_011751.1 3135515 3136480 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3135515..3136480 Escherichia coli UMN026 7157978 YP_002413722.1 CDS norR NC_011751.1 3136477 3137991 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator complement(3136477..3137991) Escherichia coli UMN026 7156630 YP_002413723.1 CDS norV NC_011751.1 3138178 3139617 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3138178..3139617 Escherichia coli UMN026 7157294 YP_002413724.1 CDS norW NC_011751.1 3139614 3140747 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3139614..3140747 Escherichia coli UMN026 7157295 YP_002413725.1 CDS hypF NC_011751.1 3140825 3143137 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12377778, 92255260, 8661925; Product type e : enzyme; carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases complement(3140825..3143137) Escherichia coli UMN026 7157296 YP_002413726.1 CDS hydN NC_011751.1 3143218 3143745 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(3143218..3143745) Escherichia coli UMN026 7156775 YP_002413727.1 CDS ascG NC_011751.1 3143894 3144907 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type r : regulator; DNA-binding transcriptional repressor complement(3143894..3144907) Escherichia coli UMN026 7156757 YP_002413728.1 CDS ascF NC_011751.1 3145164 3146621 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC 3145164..3146621 Escherichia coli UMN026 7155808 YP_002413729.1 CDS ascB NC_011751.1 3146630 3148054 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type e : enzyme; cryptic 6-phospho-beta-glucosidase 3146630..3148054 Escherichia coli UMN026 7155807 YP_002413730.1 CDS hycI NC_011751.1 3148212 3148682 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3148212..3148682) Escherichia coli UMN026 7155806 YP_002413731.1 CDS hycH NC_011751.1 3148675 3149085 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 1625581, 2187144, 7851435; Product type f : factor; protein required for maturation of hydrogenase 3 complement(3148675..3149085) Escherichia coli UMN026 7156756 YP_002413732.1 CDS hycG NC_011751.1 3149082 3149849 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type e : enzyme; hydrogenase 3 and formate hydrogenase complex, HycG subunit complement(3149082..3149849) Escherichia coli UMN026 7156755 YP_002413733.1 CDS hycF NC_011751.1 3149849 3150391 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3149849..3150391) Escherichia coli UMN026 7156754 YP_002413734.1 CDS hycE NC_011751.1 3150401 3152110 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 94170785, 2187144, 8125094; Product type e : enzyme; hydrogenase 3, large subunit complement(3150401..3152110) Escherichia coli UMN026 7156753 YP_002413735.1 CDS hycD NC_011751.1 3152128 3153051 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636; Product type m : membrane component; hydrogenase 3, membrane subunit complement(3152128..3153051) Escherichia coli UMN026 7156752 YP_002413736.1 CDS hycC NC_011751.1 3153054 3154880 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3153054..3154880) Escherichia coli UMN026 7156751 YP_002413737.1 CDS hycB NC_011751.1 3154877 3155488 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type c : carrier; hydrogenase 3, Fe-S subunit complement(3154877..3155488) Escherichia coli UMN026 7156750 YP_002413738.1 CDS hycA NC_011751.1 3155613 3156074 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3155613..3156074) Escherichia coli UMN026 7156749 YP_002413739.1 CDS hypA NC_011751.1 3156286 3156636 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3156286..3156636 Escherichia coli UMN026 7156748 YP_002413740.1 CDS hypB NC_011751.1 3156640 3157512 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3156640..3157512 Escherichia coli UMN026 7156770 YP_002413741.1 CDS hypC NC_011751.1 3157503 3157775 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3157503..3157775 Escherichia coli UMN026 7156771 YP_002413742.1 CDS hypD NC_011751.1 3157775 3158896 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 92255260, 1849603; Product type f : factor; protein required for maturation of hydrogenases 3157775..3158896 Escherichia coli UMN026 7156772 YP_002413743.1 CDS hypE NC_011751.1 3158935 3159903 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 9485446, 1849603; Product type e : enzyme; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 3158935..3159903 Escherichia coli UMN026 7156773 YP_002413744.1 CDS fhlA NC_011751.1 3159977 3162055 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20307603, 21557168, 90368529, 92140045, 94018617, 2118503, 2280686; Product type r : regulator; DNA-binding transcriptional activator 3159977..3162055 Escherichia coli UMN026 7156774 YP_002413745.1 CDS ECUMN_3055 NC_011751.1 3162061 3162528 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative molybdenum-pterin-binding-protein 3162061..3162528 Escherichia coli UMN026 7156343 YP_002413746.1 CDS ygbA NC_011751.1 3162567 3162911 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3162567..3162911) Escherichia coli UMN026 7155211 YP_002413747.1 CDS mutS NC_011751.1 3163198 3165759 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3163198..3165759 Escherichia coli UMN026 7158999 YP_002413748.1 CDS ECUMN_3058 NC_011751.1 3165864 3166727 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3165864..3166727 Escherichia coli UMN026 7157214 YP_002413749.1 CDS pphB NC_011751.1 3166740 3167408 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9130712; Product type e : enzyme; serine/threonine-specific protein phosphatase 2 3166740..3167408 Escherichia coli UMN026 7155212 YP_002413750.1 CDS ECUMN_3060 NC_011751.1 3167450 3167686 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; non-oxidative reversible hydroxyarylic acid decarboxylase complement(3167450..3167686) Escherichia coli UMN026 7157504 YP_002413751.1 CDS ECUMN_3061 NC_011751.1 3167697 3169124 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; putative non-oxidative hydroxyarylic acid decarboxylase complement(3167697..3169124) Escherichia coli UMN026 7155213 YP_002413752.1 CDS ECUMN_3062 NC_011751.1 3169124 3169717 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; non-oxidative reversible hydroxyarylic acid decarboxylase complement(3169124..3169717) Escherichia coli UMN026 7155214 YP_002413753.1 CDS ECUMN_3063 NC_011751.1 3169831 3170271 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15731069; Product type r : regulator; transcriptional regulator hosA 3169831..3170271 Escherichia coli UMN026 7155215 YP_002413754.1 CDS rpoS NC_011751.1 3170392 3171384 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(3170392..3171384) Escherichia coli UMN026 7155216 YP_002413755.1 CDS nlpD NC_011751.1 3171447 3172586 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3171447..3172586) Escherichia coli UMN026 7157764 YP_002413756.1 CDS pcm NC_011751.1 3172726 3173352 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3172726..3173352) Escherichia coli UMN026 7157288 YP_002413757.1 CDS surE NC_011751.1 3173346 3174107 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3173346..3174107) Escherichia coli UMN026 7157397 YP_002413758.1 CDS truD NC_011751.1 3174088 3175137 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3174088..3175137) Escherichia coli UMN026 7158014 YP_002413759.1 CDS ispF NC_011751.1 3175134 3175613 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(3175134..3175613) Escherichia coli UMN026 7158128 YP_002413760.1 CDS ispD NC_011751.1 3175613 3176323 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3175613..3176323) Escherichia coli UMN026 7156866 YP_002413761.1 CDS ftsB NC_011751.1 3176342 3176653 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3176342..3176653) Escherichia coli UMN026 7156864 YP_002413762.1 CDS ygbE NC_011751.1 3176847 3177170 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3176847..3177170) Escherichia coli UMN026 7156457 YP_002413763.1 CDS cysC NC_011751.1 3177220 3177825 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3177220..3177825) Escherichia coli UMN026 7159000 YP_002413764.1 CDS cysN NC_011751.1 3177825 3179252 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3177825..3179252) Escherichia coli UMN026 7156080 YP_002413765.1 CDS cysD NC_011751.1 3179254 3180162 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3179254..3180162) Escherichia coli UMN026 7156089 YP_002413766.1 CDS iap NC_011751.1 3180414 3181451 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 3180414..3181451 Escherichia coli UMN026 7156081 YP_002413769.1 CDS ygbF NC_011751.1 3182695 3182988 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3182695..3182988) Escherichia coli UMN026 7155218 YP_002413770.1 CDS ECUMN_3083 NC_011751.1 3183905 3184693 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3183905..3184693) Escherichia coli UMN026 7159003 YP_002413771.1 CDS ECUMN_3084 NC_011751.1 3184537 3185283 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3184537..3185283) Escherichia coli UMN026 7155219 YP_002413772.1 CDS ECUMN_3085 NC_011751.1 3185294 3186349 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3185294..3186349) Escherichia coli UMN026 7155220 YP_002413773.1 CDS ECUMN_3086 NC_011751.1 3186364 3186900 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3186364..3186900) Escherichia coli UMN026 7155221 YP_002413774.1 CDS ECUMN_3087 NC_011751.1 3186897 3188465 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3186897..3188465) Escherichia coli UMN026 7155222 YP_002413775.1 CDS ECUMN_3088 NC_011751.1 3188557 3191256 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3188557..3191256) Escherichia coli UMN026 7155223 YP_002413776.1 CDS ECUMN_3089 NC_011751.1 3191451 3191603 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type pm : putative membrane component; small toxic peptide complement(3191451..3191603) Escherichia coli UMN026 7155224 YP_002413777.1 CDS cysH NC_011751.1 3191868 3192602 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3191868..3192602) Escherichia coli UMN026 7155225 YP_002413778.1 CDS cysI NC_011751.1 3192676 3194388 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3192676..3194388) Escherichia coli UMN026 7156084 YP_002413779.1 CDS cysJ NC_011751.1 3194388 3196187 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3194388..3196187) Escherichia coli UMN026 7156085 YP_002413780.1 CDS ygcM NC_011751.1 3196503 3196868 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123838; Product type e : enzyme; 6-pyruvoyl tetrahydrobiopterin synthase 3196503..3196868 Escherichia coli UMN026 7156086 YP_002413781.1 CDS ygcN NC_011751.1 3196946 3198217 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 3196946..3198217 Escherichia coli UMN026 7159007 YP_002413782.1 CDS ygcO NC_011751.1 3198208 3198468 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S cluster-containing protein 3198208..3198468 Escherichia coli UMN026 7159008 YP_002413783.1 CDS ygcP NC_011751.1 3198485 3199060 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative anti-terminator regulatory protein 3198485..3199060 Escherichia coli UMN026 7159009 YP_002413784.1 CDS ygcQ NC_011751.1 3199207 3200067 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative flavoprotein complement(3199207..3200067) Escherichia coli UMN026 7159010 YP_002413785.1 CDS ygcR NC_011751.1 3200064 3200843 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative flavoprotein complement(3200064..3200843) Escherichia coli UMN026 7159011 YP_002413786.1 CDS ygcS NC_011751.1 3200821 3202158 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(3200821..3202158) Escherichia coli UMN026 7159012 YP_002413787.1 CDS ygcU NC_011751.1 3202252 3203706 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative FAD containing dehydrogenase complement(3202252..3203706) Escherichia coli UMN026 7159013 YP_002413788.1 CDS ygcW NC_011751.1 3203776 3204561 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative deoxygluconate dehydrogenase complement(3203776..3204561) Escherichia coli UMN026 7159014 YP_002413789.1 CDS yqcE NC_011751.1 3204880 3206157 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3204880..3206157 Escherichia coli UMN026 7159015 YP_002413790.1 CDS ygcE NC_011751.1 3206184 3207662 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative kinase 3206184..3207662 Escherichia coli UMN026 7159600 YP_002413791.1 CDS ygcF NC_011751.1 3209218 3209889 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3209218..3209889) Escherichia coli UMN026 7159004 YP_002413792.1 CDS ECUMN_3105 NC_011751.1 3210062 3210664 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3210062..3210664 Escherichia coli UMN026 7159005 YP_002413793.1 CDS ygcG NC_011751.1 3210648 3211571 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3210648..3211571 Escherichia coli UMN026 7155226 YP_002413794.1 CDS ECUMN_3107 NC_011751.1 3211586 3212734 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3211586..3212734 Escherichia coli UMN026 7159006 YP_002413795.1 CDS ECUMN_3109 NC_011751.1 3212728 3213645 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3212728..3213645 Escherichia coli UMN026 7155227 YP_002413796.1 CDS eno NC_011751.1 3213705 3215003 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3213705..3215003) Escherichia coli UMN026 7155228 YP_002413797.1 CDS pyrG NC_011751.1 3215090 3216727 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3215090..3216727) Escherichia coli UMN026 7156247 YP_002413798.1 CDS mazG NC_011751.1 3216955 3217746 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(3216955..3217746) Escherichia coli UMN026 7157602 YP_002413799.1 CDS relA NC_011751.1 3217842 3220076 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3217842..3220076) Escherichia coli UMN026 7157064 YP_002413800.1 CDS rumA NC_011751.1 3220124 3221425 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3220124..3221425) Escherichia coli UMN026 7157649 YP_002413801.1 CDS barA NC_011751.1 3221482 3224238 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3221482..3224238 Escherichia coli UMN026 7157817 YP_002413802.1 CDS gudD NC_011751.1 3224469 3225809 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233700, 9772162, 10762278, 13971911; Product type e : enzyme; (D)-glucarate dehydratase 1 complement(3224469..3225809) Escherichia coli UMN026 7155851 YP_002413803.1 CDS gudX NC_011751.1 3225830 3227170 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9772162; Product type e : enzyme; glucarate dehydratase complement(3225830..3227170) Escherichia coli UMN026 7156626 YP_002413804.1 CDS gudP NC_011751.1 3227172 3228524 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10762278; Product type pt : putative transporter; putative D-glucarate transporter complement(3227172..3228524) Escherichia coli UMN026 7156628 YP_002413805.1 CDS yqcA NC_011751.1 3228999 3229448 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3228999..3229448) Escherichia coli UMN026 7156627 YP_002413806.1 CDS truC NC_011751.1 3229466 3230248 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3229466..3230248) Escherichia coli UMN026 7159598 YP_002413807.1 CDS yqcC NC_011751.1 3230248 3230577 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3230248..3230577) Escherichia coli UMN026 7158127 YP_002413808.1 CDS syd NC_011751.1 3231199 3231744 R putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3231199..3231744) Escherichia coli UMN026 7156044 YP_002413809.1 CDS queF NC_011751.1 3231812 3232660 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3231812..3232660 Escherichia coli UMN026 7158015 YP_002413810.1 CDS ygdH NC_011751.1 3232772 3234136 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3232772..3234136 Escherichia coli UMN026 7157614 YP_002413811.1 CDS sdaC NC_011751.1 3234693 3235982 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8752353, 8026499; Product type pt : putative transporter; putative serine transporter 3234693..3235982 Escherichia coli UMN026 7159019 YP_002413812.1 CDS sdaB NC_011751.1 3236040 3237407 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193203, 93215657, 8385012; Product type e : enzyme; L-serine deaminase II 3236040..3237407 Escherichia coli UMN026 7157879 YP_002413813.1 CDS xni NC_011751.1 3237428 3238273 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3237428..3238273 Escherichia coli UMN026 7157878 YP_002413814.1 CDS fucO NC_011751.1 3238378 3239529 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 89291720, 2553671, 2661535, 2664711, 8385012; Product type e : enzyme; L-1,2-propanediol oxidoreductase complement(3238378..3239529) Escherichia coli UMN026 7156289 YP_002413815.1 CDS fucA NC_011751.1 3239554 3240201 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3239554..3240201) Escherichia coli UMN026 7156472 YP_002413816.1 CDS fucP NC_011751.1 3240748 3242064 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2553671, 2664711, 7783647; Product type t : transporter; L-fucose transporter 3240748..3242064 Escherichia coli UMN026 7156469 YP_002413817.1 CDS fucI NC_011751.1 3242097 3243872 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3242097..3243872 Escherichia coli UMN026 7156473 YP_002413818.1 CDS fucK NC_011751.1 3243951 3245399 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2664711, 13905785; Product type e : enzyme; L-fuculokinase 3243951..3245399 Escherichia coli UMN026 7156470 YP_002413819.1 CDS fucU NC_011751.1 3245401 3245823 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078, 12738765, 80049526, 2664711; Product type e : enzyme; L-fucose mutarotase 3245401..3245823 Escherichia coli UMN026 7156471 YP_002413820.1 CDS fucR NC_011751.1 3245881 3246612 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3245881..3246612 Escherichia coli UMN026 7156475 YP_002413821.1 CDS ygdE NC_011751.1 3246656 3247756 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21188420, 7704273; Product type pe : putative enzyme; putative RNA 2'-O-ribose methyltransferase complement(3246656..3247756) Escherichia coli UMN026 7156474 YP_002413822.1 CDS ygdD NC_011751.1 3247749 3248144 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7704273; Product type pm : putative membrane component; hypothetical protein complement(3247749..3248144) Escherichia coli UMN026 7159018 YP_002413823.1 CDS gcvA NC_011751.1 3248163 3249080 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3248163..3249080) Escherichia coli UMN026 7159017 YP_002413824.1 CDS ECUMN_3138 NC_011751.1 3249375 3249692 D Evidence 6 : Doubtful CDS; hypothetical protein 3249375..3249692 Escherichia coli UMN026 7156521 YP_002413825.1 CDS ygdI NC_011751.1 3249432 3249659 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3249432..3249659) Escherichia coli UMN026 7155229 YP_002413826.1 CDS csdA NC_011751.1 3249851 3251056 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15148362, 9278392, 10739946, 10829016; Product type e : enzyme; cysteine sulfinate desulfinase 3249851..3251056 Escherichia coli UMN026 7159020 YP_002413827.1 CDS ygdK NC_011751.1 3251056 3251499 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Fe-S metabolism protein (sufE-like) 3251056..3251499 Escherichia coli UMN026 7156024 YP_002413828.1 CDS ygdL NC_011751.1 3251550 3252356 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3251550..3252356) Escherichia coli UMN026 7159021 YP_002413829.1 CDS mltA NC_011751.1 3252595 3253692 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3252595..3253692) Escherichia coli UMN026 7159022 YP_002413830.1 CDS amiC NC_011751.1 3254380 3255633 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12787347, 21348478; Product type e : enzyme; N-acetylmuramoyl-L-alanine amidase complement(3254380..3255633) Escherichia coli UMN026 7155586 YP_002413831.1 CDS argA NC_011751.1 3255865 3257196 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3255865..3257196 Escherichia coli UMN026 7155735 YP_002413832.1 CDS recD NC_011751.1 3257258 3259084 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3257258..3259084) Escherichia coli UMN026 7155768 YP_002413833.1 CDS recB NC_011751.1 3259084 3262626 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3259084..3262626) Escherichia coli UMN026 7157640 YP_002413834.1 CDS ptr NC_011751.1 3262619 3265507 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193232, 1570301, 3308636, 3534791, 3537960, 8099278; Product type e : enzyme; protease III complement(3262619..3265507) Escherichia coli UMN026 7157638 YP_002413835.1 CDS recC NC_011751.1 3265683 3269051 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3265683..3269051) Escherichia coli UMN026 7157563 YP_002413836.1 CDS ppdC NC_011751.1 3269064 3269387 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme; hypothetical protein complement(3269064..3269387) Escherichia coli UMN026 7157639 YP_002413837.1 CDS ygdB NC_011751.1 3269372 3269779 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3269372..3269779) Escherichia coli UMN026 7157501 YP_002413838.1 CDS ppdB NC_011751.1 3269776 3270339 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme; hypothetical protein complement(3269776..3270339) Escherichia coli UMN026 7159016 YP_002413839.1 CDS ppdA NC_011751.1 3270330 3270800 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme; hypothetical protein complement(3270330..3270800) Escherichia coli UMN026 7157500 YP_002413840.1 CDS thyA NC_011751.1 3270985 3271779 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3270985..3271779) Escherichia coli UMN026 7157499 YP_002413841.1 CDS lgt NC_011751.1 3271786 3272661 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3271786..3272661) Escherichia coli UMN026 7158069 YP_002413842.1 CDS ptsP NC_011751.1 3272812 3275058 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; bifunctional phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein complement(3272812..3275058) Escherichia coli UMN026 7156977 YP_002413843.1 CDS nudH NC_011751.1 3275071 3275601 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3275071..3275601) Escherichia coli UMN026 7157571 YP_002413844.1 CDS mutH NC_011751.1 3276286 3276975 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3276286..3276975 Escherichia coli UMN026 7157322 YP_002413845.1 CDS ygdQ NC_011751.1 3277044 3277757 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3277044..3277757 Escherichia coli UMN026 7157211 YP_002413846.1 CDS ygdR NC_011751.1 3277895 3278113 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3277895..3278113 Escherichia coli UMN026 7159023 YP_002413847.1 CDS tas NC_011751.1 3278221 3279261 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase 3278221..3279261 Escherichia coli UMN026 7159024 YP_002413848.1 CDS ygeD NC_011751.1 3279293 3280486 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8300626; Product type pm : putative membrane component; lysophospholipid transporter LplT complement(3279293..3280486) Escherichia coli UMN026 7158024 YP_002413849.1 CDS aas NC_011751.1 3280479 3282638 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3280479..3282638) Escherichia coli UMN026 7159025 YP_002413850.1 CDS galR NC_011751.1 3283224 3284255 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3283224..3284255 Escherichia coli UMN026 7157354 YP_002413851.1 CDS lysA NC_011751.1 3284262 3285524 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3284262..3285524) Escherichia coli UMN026 7156498 YP_002413852.1 CDS lysR NC_011751.1 3285646 3286581 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 3285646..3286581 Escherichia coli UMN026 7157029 YP_002413853.1 CDS ECUMN_3168 NC_011751.1 3286568 3287635 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative racemase complement(3286568..3287635) Escherichia coli UMN026 7157032 YP_002413854.1 CDS araE NC_011751.1 3287389 3288807 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7030324, 90239116, 91154204, 2836407, 3543693, 6319708; Product type t : transporter; arabinose transporter complement(3287389..3288807) Escherichia coli UMN026 7155230 YP_002413855.1 CDS kduD NC_011751.1 3289122 3289883 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3289122..3289883) Escherichia coli UMN026 7155761 YP_002413856.1 CDS kduI NC_011751.1 3289913 3290749 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3289913..3290749) Escherichia coli UMN026 7156900 YP_002413857.1 CDS yqeF NC_011751.1 3291037 3292218 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3291037..3292218) Escherichia coli UMN026 7156901 YP_002413858.1 CDS yqeG NC_011751.1 3292474 3293703 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3292474..3293703 Escherichia coli UMN026 7159604 YP_002413859.1 CDS yqeH NC_011751.1 3294163 3294795 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3294163..3294795 Escherichia coli UMN026 7159605 YP_002413860.1 CDS yqeI NC_011751.1 3295129 3295938 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 3295129..3295938 Escherichia coli UMN026 7159606 YP_002413861.1 CDS yqeJ NC_011751.1 3295931 3296413 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3295931..3296413 Escherichia coli UMN026 7159607 YP_002413862.1 CDS yqeK NC_011751.1 3296562 3296987 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3296562..3296987) Escherichia coli UMN026 7159608 YP_002413863.1 CDS ECUMN_3179 NC_011751.1 3297027 3297176 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3297027..3297176) Escherichia coli UMN026 7159609 YP_002413864.1 CDS ygeF NC_011751.1 3297417 3297908 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3297417..3297908 Escherichia coli UMN026 7155231 YP_002413865.1 CDS ygeG NC_011751.1 3298134 3298625 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative chaperone 3298134..3298625 Escherichia coli UMN026 7159026 YP_002413866.1 CDS ygeH NC_011751.1 3298960 3300336 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15150243; Product type pr : putative regulator; transcriptional regulator 3298960..3300336 Escherichia coli UMN026 7159027 YP_002413867.1 CDS ygeI NC_011751.1 3300462 3300722 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3300462..3300722 Escherichia coli UMN026 7159028 YP_002413868.1 CDS ECUMN_3184 NC_011751.1 3300806 3301309 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidoglycan-binding-like protein 3300806..3301309 Escherichia coli UMN026 7159029 YP_002413869.1 CDS ECUMN_3185 NC_011751.1 3301328 3301960 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3301328..3301960) Escherichia coli UMN026 7155232 YP_002413870.1 CDS ECUMN_3186 NC_011751.1 3302183 3302953 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3302183..3302953) Escherichia coli UMN026 7155233 YP_002413871.1 CDS ECUMN_3187 NC_011751.1 3302832 3303413 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12791847; hypothetical protein complement(3302832..3303413) Escherichia coli UMN026 7155234 YP_002413872.1 CDS eprK NC_011751.1 3303429 3304163 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12791847; Product type pm : putative membrane component; putative type III secretion system lipoprotein EprK complement(3303429..3304163) Escherichia coli UMN026 7155235 YP_002413873.1 CDS ECUMN_3189 NC_011751.1 3304160 3304492 R Evidence 4 : Homologs of previously reported genes of unknown function; putative type III secretion apparatus protein complement(3304160..3304492) Escherichia coli UMN026 7156261 YP_002413874.1 CDS prgI NC_011751.1 3304512 3304751 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16501225; Product type f : factor; type III secretion system needle protein complement(3304512..3304751) Escherichia coli UMN026 7155236 YP_002413875.1 CDS eprH NC_011751.1 3304765 3305955 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative type III secretion EprH protein complement(3304765..3305955) Escherichia coli UMN026 7157521 YP_002413876.1 CDS ECUMN_3192 NC_011751.1 3306205 3306705 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12791847; putative response regulator 3306205..3306705 Escherichia coli UMN026 7156260 YP_002413877.1 CDS ECUMN_3193 NC_011751.1 3306707 3307000 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12791847; hypothetical protein 3306707..3307000 Escherichia coli UMN026 7155237 YP_002413878.1 CDS spaS NC_011751.1 3307071 3308183 R Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins; surface presentation of antigens protein SpaS complement(3307071..3308183) Escherichia coli UMN026 7155238 YP_002413879.1 CDS ECUMN_3195 NC_011751.1 3308192 3308959 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12791847; Product type pm : putative membrane component; putative type III secretion protein EpaR complement(3308192..3308959) Escherichia coli UMN026 7157956 YP_002413880.1 CDS spaQ NC_011751.1 3308961 3309308 R Evidence 2b : Function of strongly homologous gene; Product type pm : putative membrane component; surface presentation of antigens protein complement(3308961..3309308) Escherichia coli UMN026 7155239 YP_002413881.1 CDS spaP NC_011751.1 3309232 3309897 R part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP complement(3309232..3309897) Escherichia coli UMN026 7157955 YP_002413882.1 CDS epaO NC_011751.1 3309887 3310834 R involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; surface presentation of antigens protein SpaO complement(3309887..3310834) Escherichia coli UMN026 7155240 YP_002413883.1 CDS eivJ NC_011751.1 3310834 3311709 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; type III secretion protein complement(3310834..3311709) Escherichia coli UMN026 7156258 YP_002413884.1 CDS ECUMN_3200 NC_011751.1 3311687 3312154 R Evidence 2b : Function of strongly homologous gene; Product type pt : putative transporter; type III secretion apparatus protein complement(3311687..3312154) Escherichia coli UMN026 7156233 YP_002413885.1 CDS ECUMN_3201 NC_011751.1 3312135 3313454 R Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase; ATP synthase SpaL complement(3312135..3313454) Escherichia coli UMN026 7155241 YP_002413886.1 CDS invA NC_011751.1 3313459 3315519 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1624429; Product type t : transporter; invasion protein complement(3313459..3315519) Escherichia coli UMN026 7155242 YP_002413887.1 CDS ECUMN_3203 NC_011751.1 3315512 3316681 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; hypothetical protein complement(3315512..3316681) Escherichia coli UMN026 7156846 YP_002413888.1 CDS ECUMN_3204 NC_011751.1 3316662 3318365 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; protein invG complement(3316662..3318365) Escherichia coli UMN026 7155243 YP_002413889.1 CDS ECUMN_3205 NC_011751.1 3318362 3319111 R Evidence 2b : Function of strongly homologous gene; Product type pr : putative regulator; Invasion protein invF complement(3318362..3319111) Escherichia coli UMN026 7155244 YP_002413890.1 CDS ECUMN_3207 NC_011751.1 3319702 3321354 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3319702..3321354) Escherichia coli UMN026 7155245 YP_002413891.1 CDS ygeR NC_011751.1 3321697 3322473 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15150243; Product type r : regulator; Tetratricopeptide repeat transcriptional regulator complement(3321697..3322473) Escherichia coli UMN026 7155623 YP_002413892.1 CDS xdhA NC_011751.1 3322904 3325162 D putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3322904..3325162 Escherichia coli UMN026 7159030 YP_002413893.1 CDS xdhB NC_011751.1 3325173 3326051 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3325173..3326051 Escherichia coli UMN026 7158242 YP_002413894.1 CDS xdhC NC_011751.1 3326048 3326527 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3326048..3326527 Escherichia coli UMN026 7158243 YP_002413895.1 CDS ygeV NC_011751.1 3326567 3328345 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3326567..3328345) Escherichia coli UMN026 7158244 YP_002413896.1 CDS ygeW NC_011751.1 3328822 3330012 D Evidence 4 : Homologs of previously reported genes of unknown function; aspartate/ornithine carbamoyltransferase family protein 3328822..3330012 Escherichia coli UMN026 7159031 YP_002413897.1 CDS ygeX NC_011751.1 3330070 3331266 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3330070..3331266 Escherichia coli UMN026 7159032 YP_002413898.1 CDS ygeY NC_011751.1 3331324 3332535 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3331324..3332535 Escherichia coli UMN026 7159033 YP_002413899.1 CDS hyuA NC_011751.1 3332588 3333973 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3332588..3333973 Escherichia coli UMN026 7159034 YP_002413900.1 CDS yqeA NC_011751.1 3334021 3334953 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3334021..3334953 Escherichia coli UMN026 7156776 YP_002413901.1 CDS yqeB NC_011751.1 3335173 3336798 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3335173..3336798) Escherichia coli UMN026 7159601 YP_002413902.1 CDS yqeC NC_011751.1 3336846 3337616 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3336846..3337616) Escherichia coli UMN026 7159602 YP_002413903.1 CDS ygfJ NC_011751.1 3337719 3338297 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3337719..3338297 Escherichia coli UMN026 7159603 YP_002413904.1 CDS ygfK NC_011751.1 3338619 3341717 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 3338619..3341717 Escherichia coli UMN026 7159040 YP_002413905.1 CDS ssnA NC_011751.1 3341720 3343048 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 3341720..3343048 Escherichia coli UMN026 7159041 YP_002413906.1 CDS ygfM NC_011751.1 3343099 3343878 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM 3343099..3343878 Escherichia coli UMN026 7157985 YP_002413907.1 CDS xdhD NC_011751.1 3343875 3346745 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN 3343875..3346745 Escherichia coli UMN026 7159042 YP_002413908.1 CDS ygfO NC_011751.1 3346910 3348310 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20372655, 98213740; Product type pt : putative transporter; putative transporter 3346910..3348310 Escherichia coli UMN026 7158245 YP_002413909.1 CDS guaD NC_011751.1 3348325 3349644 D Catalyzes the deamination of guanine; guanine deaminase 3348325..3349644 Escherichia coli UMN026 7159043 YP_002413910.1 CDS ygfQ NC_011751.1 3349680 3351047 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3349680..3351047 Escherichia coli UMN026 7156625 YP_002413911.1 CDS ygfS NC_011751.1 3351083 3351571 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative oxidoreductase complement(3351083..3351571) Escherichia coli UMN026 7159044 YP_002413912.1 CDS ygfT NC_011751.1 3351571 3353490 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit complement(3351571..3353490) Escherichia coli UMN026 7159045 YP_002413913.1 CDS ygfU NC_011751.1 3353926 3355374 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9098051; Product type t : transporter; transporter 3353926..3355374 Escherichia coli UMN026 7159046 YP_002413914.1 CDS idi NC_011751.1 3355624 3356172 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3355624..3356172 Escherichia coli UMN026 7159047 YP_002413915.1 CDS lysS NC_011751.1 3356215 3357732 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3356215..3357732) Escherichia coli UMN026 7156787 YP_002413916.1 CDS prfB NC_011751.1 3357742 3358840 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(join(3357742..3358764,3358766..3358840)) Escherichia coli UMN026 7157033 YP_002413917.1 CDS recJ NC_011751.1 3358931 3360664 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3358931..3360664) Escherichia coli UMN026 7157518 YP_002413918.1 CDS dsbC NC_011751.1 3360670 3361380 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3360670..3361380) Escherichia coli UMN026 7157643 YP_002413919.1 CDS xerD NC_011751.1 3361405 3362301 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3361405..3362301) Escherichia coli UMN026 7156204 YP_002413920.1 CDS fldB NC_011751.1 3362413 3362934 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3362413..3362934 Escherichia coli UMN026 7158247 YP_002413921.1 CDS ygfX NC_011751.1 3362974 3363381 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3362974..3363381) Escherichia coli UMN026 7156376 YP_002413922.1 CDS ygfY NC_011751.1 3363362 3363628 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3363362..3363628) Escherichia coli UMN026 7159048 YP_002413923.1 CDS ygfZ NC_011751.1 3363871 3364851 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator 3363871..3364851 Escherichia coli UMN026 7159049 YP_002413924.1 CDS yqfA NC_011751.1 3364928 3365587 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative hemolysin, inner membrane subunit complement(3364928..3365587) Escherichia coli UMN026 7159050 YP_002413925.1 CDS yqfB NC_011751.1 3365751 3366062 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3365751..3366062) Escherichia coli UMN026 7159610 YP_002413926.1 CDS bglA NC_011751.1 3366101 3367540 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140; Product type e : enzyme; 6-phospho-beta-glucosidase A 3366101..3367540 Escherichia coli UMN026 7159611 YP_002413927.1 CDS gcvP NC_011751.1 3367706 3370579 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3367706..3370579) Escherichia coli UMN026 7155873 YP_002413928.1 CDS gcvH NC_011751.1 3370698 3371087 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3370698..3371087) Escherichia coli UMN026 7156523 YP_002413929.1 CDS gcvT NC_011751.1 3371111 3372205 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3371111..3372205) Escherichia coli UMN026 7156522 YP_002413930.1 CDS visC NC_011751.1 3372653 3373855 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1339425; Product type pe : putative enzyme; hypothetical protein complement(3372653..3373855) Escherichia coli UMN026 7156525 YP_002413931.1 CDS ubiH NC_011751.1 3373878 3375056 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3373878..3375056) Escherichia coli UMN026 7158211 YP_002413932.1 CDS pepP NC_011751.1 3375053 3376378 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3375053..3376378) Escherichia coli UMN026 7158159 YP_002413933.1 CDS ygfB NC_011751.1 3376404 3376982 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3376404..3376982) Escherichia coli UMN026 7157415 YP_002413934.1 CDS zapA NC_011751.1 3377150 3377479 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 412171; Product type cp : cell process; Z-ring-associated protein 3377150..3377479 Escherichia coli UMN026 7159036 YP_002413935.1 CDS ygfA NC_011751.1 3377779 3378327 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase 3377779..3378327 Escherichia coli UMN026 7157989 YP_002413936.1 CDS serA NC_011751.1 3378716 3379948 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3378716..3379948) Escherichia coli UMN026 7157852 YP_002413937.1 CDS rpiA NC_011751.1 3380204 3380863 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3380204..3380863) Escherichia coli UMN026 7157897 YP_002413938.1 CDS ECUMN_3256 NC_011751.1 3380919 3381815 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3380919..3381815) Escherichia coli UMN026 7157724 YP_002413939.1 CDS ECUMN_3257 NC_011751.1 3381916 3382545 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; FMN-dependent NADH-azoreductase 3381916..3382545 Escherichia coli UMN026 7155247 YP_002413940.1 CDS ECUMN_3258 NC_011751.1 3382562 3382822 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3382562..3382822 Escherichia coli UMN026 7155248 YP_002413941.1 CDS ECUMN_3259 NC_011751.1 3382884 3384209 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Flavodoxin oxidoreductase 3382884..3384209 Escherichia coli UMN026 7155249 YP_002413942.1 CDS argP NC_011751.1 3384280 3385173 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3384280..3385173 Escherichia coli UMN026 7155250 YP_002413943.1 CDS yliK NC_011751.1 3385377 3387521 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3385377..3387521 Escherichia coli UMN026 7155778 YP_002413944.1 CDS argK NC_011751.1 3387514 3388509 D functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3387514..3388509 Escherichia coli UMN026 7159472 YP_002413945.1 CDS ygfG NC_011751.1 3388520 3389305 D catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3388520..3389305 Escherichia coli UMN026 7155776 YP_002413946.1 CDS ygfH NC_011751.1 3389329 3390807 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233703; Product type e : enzyme; propionyl-CoA:succinate-CoA transferase 3389329..3390807 Escherichia coli UMN026 7159037 YP_002413947.1 CDS ygfI NC_011751.1 3390804 3391700 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3390804..3391700) Escherichia coli UMN026 7159038 YP_002413948.1 CDS yggE NC_011751.1 3391868 3392608 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3391868..3392608) Escherichia coli UMN026 7159039 YP_002413949.1 CDS argO NC_011751.1 3392701 3393336 R Involved in the export of arginine; arginine exporter protein complement(3392701..3393336) Escherichia coli UMN026 7159053 YP_002413950.1 CDS ECUMN_3268 NC_011751.1 3393452 3394495 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3393452..3394495 Escherichia coli UMN026 7155777 YP_002413951.1 CDS mscS NC_011751.1 3394537 3395412 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3394537..3395412) Escherichia coli UMN026 7155251 YP_002413952.1 CDS fbaA NC_011751.1 3395770 3396849 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3395770..3396849) Escherichia coli UMN026 7157186 YP_002413953.1 CDS pgk NC_011751.1 3397063 3398226 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3397063..3398226) Escherichia coli UMN026 7156309 YP_002413954.1 CDS epd NC_011751.1 3398276 3399295 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3398276..3399295) Escherichia coli UMN026 7157427 YP_002413955.1 CDS ECUMN_3273 NC_011751.1 3399667 3400098 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3399667..3400098 Escherichia coli UMN026 7156259 YP_002413956.1 CDS ECUMN_3274 NC_011751.1 3400022 3400699 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC-type transport system 3400022..3400699 Escherichia coli UMN026 7155252 YP_002413957.1 CDS ECUMN_3275 NC_011751.1 3400700 3401407 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC-type transport system 3400700..3401407 Escherichia coli UMN026 7155253 YP_002413958.1 CDS ECUMN_3276 NC_011751.1 3401389 3402072 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 3401389..3402072 Escherichia coli UMN026 7155254 YP_002413959.1 CDS ECUMN_3277 NC_011751.1 3402033 3402743 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 3402033..3402743 Escherichia coli UMN026 7155255 YP_002413960.1 CDS frcK NC_011751.1 3402715 3403428 R Evidence 4 : Homologs of previously reported genes of unknown function; putative fructose transport system kinase complement(3402715..3403428) Escherichia coli UMN026 7155256 YP_002413961.1 CDS yggD NC_011751.1 3403425 3403934 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3403425..3403934) Escherichia coli UMN026 7159051 YP_002413962.1 CDS yggF NC_011751.1 3403956 3404921 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; fructose-1,6-bisphosphatase II-like protein complement(3403956..3404921) Escherichia coli UMN026 7159052 YP_002413963.1 CDS yggP NC_011751.1 3404918 3406195 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dehydrogenase complement(3404918..3406195) Escherichia coli UMN026 7159054 YP_002413964.1 CDS cmtA NC_011751.1 3406210 3407598 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8353127; Product type t : transporter; PTS system mannitol-specific transporter subunit IIBC complement(3406210..3407598) Escherichia coli UMN026 7159061 YP_002413965.1 CDS cmtB NC_011751.1 3407626 3408069 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; putative mannitol phosphotransferase subunit EIIA complement(3407626..3408069) Escherichia coli UMN026 7155986 YP_002413966.1 CDS ECUMN_3284 NC_011751.1 3408410 3409354 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane protease 3408410..3409354 Escherichia coli UMN026 7155987 YP_002413967.1 CDS tktA NC_011751.1 3409748 3411739 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3409748..3411739) Escherichia coli UMN026 7155257 YP_002413968.1 CDS yggG NC_011751.1 3412017 3412775 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1310091; Product type pe : putative enzyme; putative peptidase 3412017..3412775 Escherichia coli UMN026 7158074 YP_002413969.1 CDS ECUMN_3287 NC_011751.1 3412861 3414423 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3412861..3414423) Escherichia coli UMN026 7159055 YP_002413970.1 CDS speB NC_011751.1 3414573 3415493 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3414573..3415493) Escherichia coli UMN026 7155258 YP_002413971.1 CDS ECUMN_3289 NC_011751.1 3415629 3416360 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3415629..3416360) Escherichia coli UMN026 7157958 YP_002413972.1 CDS speA NC_011751.1 3416506 3418482 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3416506..3418482) Escherichia coli UMN026 7155259 YP_002413973.1 CDS yqgB NC_011751.1 3418491 3418637 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3418491..3418637) Escherichia coli UMN026 7157957 YP_002413974.1 CDS yqgC NC_011751.1 3418758 3418973 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3418758..3418973 Escherichia coli UMN026 7159613 YP_002413975.1 CDS yqgD NC_011751.1 3418970 3419221 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3418970..3419221) Escherichia coli UMN026 7159614 YP_002413976.1 CDS metK NC_011751.1 3419277 3420431 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3419277..3420431 Escherichia coli UMN026 7159615 YP_002413977.1 CDS galP NC_011751.1 3420868 3422262 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9182541; Product type t : transporter; D-galactose transporter 3420868..3422262 Escherichia coli UMN026 7157109 YP_002413978.1 CDS sprT NC_011751.1 3422339 3422836 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7984428, 8113204; hypothetical protein 3422339..3422836 Escherichia coli UMN026 7156497 YP_002413979.1 CDS endA NC_011751.1 3422931 3423638 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 72060411, 92335461, 4955462, 7867949, 8113204; Product type e : enzyme; DNA-specific endonuclease I 3422931..3423638 Escherichia coli UMN026 7157967 YP_002413980.1 CDS yggJ NC_011751.1 3423718 3424449 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3423718..3424449 Escherichia coli UMN026 7156246 YP_002413981.1 CDS gshB NC_011751.1 3424462 3425412 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3424462..3425412 Escherichia coli UMN026 7159057 YP_002413982.1 CDS yqgE NC_011751.1 3425521 3426084 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3425521..3426084 Escherichia coli UMN026 7156618 YP_002413983.1 CDS yqgF NC_011751.1 3426084 3426500 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3426084..3426500 Escherichia coli UMN026 7159616 YP_002413984.1 CDS yggR NC_011751.1 3426615 3427595 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1676385; Product type t : transporter; transporter complement(3426615..3427595) Escherichia coli UMN026 7159617 YP_002413985.1 CDS yggS NC_011751.1 3427613 3428317 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3427613..3428317 Escherichia coli UMN026 7159062 YP_002413986.1 CDS yggT NC_011751.1 3428335 3428901 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3428335..3428901 Escherichia coli UMN026 7159063 YP_002413987.1 CDS yggU NC_011751.1 3428898 3429188 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12975589; hypothetical protein 3428898..3429188 Escherichia coli UMN026 7159064 YP_002413988.1 CDS yggV NC_011751.1 3429196 3429789 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 3429196..3429789 Escherichia coli UMN026 7159065 YP_002413989.1 CDS yggW NC_011751.1 3429782 3430918 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3429782..3430918 Escherichia coli UMN026 7159066 YP_002413990.1 CDS ECUMN_3308 NC_011751.1 3431231 3432217 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative c4-dicarboxylate transport system binding protein 3431231..3432217 Escherichia coli UMN026 7159067 YP_002413991.1 CDS ECUMN_3309 NC_011751.1 3432253 3432765 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative TRAP-type C4-dicarboxylate transport system, small permease 3432253..3432765 Escherichia coli UMN026 7155260 YP_002413992.1 CDS ygiK NC_011751.1 3432765 3434066 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; c4-dicarboxylate permease 3432765..3434066 Escherichia coli UMN026 7155261 YP_002413993.1 CDS yggM NC_011751.1 3434122 3435129 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3434122..3435129) Escherichia coli UMN026 7159088 YP_002413994.1 CDS ansB NC_011751.1 3435246 3436292 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3435246..3436292) Escherichia coli UMN026 7159059 YP_002413995.1 CDS yggN NC_011751.1 3436468 3437187 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein complement(3436468..3437187) Escherichia coli UMN026 7155746 YP_002413996.1 CDS yggL NC_011751.1 3437371 3437697 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3437371..3437697) Escherichia coli UMN026 7159060 YP_002413997.1 CDS trmB NC_011751.1 3437697 3438416 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3437697..3438416) Escherichia coli UMN026 7159058 YP_002413998.1 CDS mutY NC_011751.1 3438577 3439629 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14730969, 20187555, 20316830, 20580749, 21438845, 90046892, 92409600, 9801309, 2001994, 2197596, 9846876; Product type e : enzyme; adenine DNA glycosylase 3438577..3439629 Escherichia coli UMN026 7159056 YP_002413999.1 CDS yggX NC_011751.1 3439657 3439932 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594836, 10493123, 9298646, 9868784; Product type f : factor; hypothetical protein 3439657..3439932 Escherichia coli UMN026 7157216 YP_002414000.1 CDS mltC NC_011751.1 3439997 3441076 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3439997..3441076 Escherichia coli UMN026 7159068 YP_002414001.1 CDS nupG NC_011751.1 3441278 3442534 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88029453, 90323001, 3311747; Product type t : transporter; nucleoside transporter 3441278..3442534 Escherichia coli UMN026 7157141 YP_002414002.1 CDS speC NC_011751.1 3442583 3444718 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 87260820; Product type e : enzyme; ornithine decarboxylase complement(3442583..3444718) Escherichia coli UMN026 7157337 YP_002414003.1 CDS yqgA NC_011751.1 3445111 3445818 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3445111..3445818 Escherichia coli UMN026 7157959 YP_002414004.1 CDS ECUMN_3322 NC_011751.1 3446197 3447462 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; integrase 3446197..3447462 Escherichia coli UMN026 7155588 YP_002414005.1 CDS ECUMN_3323 NC_011751.1 3447688 3448761 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411725; Product type pe : putative enzyme; SHI-2 pathogenicity island protein 3447688..3448761 Escherichia coli UMN026 7155262 YP_002414006.1 CDS ECUMN_3326 NC_011751.1 3450184 3450588 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 3450184..3450588 Escherichia coli UMN026 7155265 YP_002414007.1 CDS ECUMN_3327 NC_011751.1 3450585 3450932 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family 3450585..3450932 Escherichia coli UMN026 7155266 YP_002414008.1 CDS ECUMN_3330 NC_011751.1 3452869 3453420 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative HTH-type transcriptional regulator complement(3452869..3453420) Escherichia coli UMN026 7155269 YP_002414009.1 CDS papG NC_011751.1 3453683 3454693 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 2895103, 11440716; Product type s : structure; Fimbrial PapG protein complement(3453683..3454693) Escherichia coli UMN026 7155270 YP_002414010.1 CDS papF NC_011751.1 3454737 3455267 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2869489, 2895103, 1357526, 8096174, 10049807; Product type s : structure; Fimbrial adapter PapF complement(3454737..3455267) Escherichia coli UMN026 7157387 YP_002414011.1 CDS prsE NC_011751.1 3455312 3455857 R Evidence 2b : Function of strongly homologous gene; Product type m : membrane component; Fimbrial protein complement(3455312..3455857) Escherichia coli UMN026 7157386 YP_002414012.1 CDS papK NC_011751.1 3455866 3456405 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 8096174, 10049807, 10446050; Product type s : structure; Fimbrial adapter PapK complement(3455866..3456405) Escherichia coli UMN026 7157547 YP_002414013.1 CDS papJ NC_011751.1 3456412 3456993 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1975085, 1357526; Product type f : factor; protein PapJ , P pilus assembly complement(3456412..3456993) Escherichia coli UMN026 7157391 YP_002414014.1 CDS papD NC_011751.1 3457030 3457764 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 10049807, 2478891, 10446050; Product type f : factor; Chaperone protein PapD complement(3457030..3457764) Escherichia coli UMN026 7157390 YP_002414015.1 CDS papC NC_011751.1 3457835 3460366 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2897064, 1357526, 12399496, 2572580, 7909802, 9501230; Product type f : factor; Outer membrane usher protein PapC complement(3457835..3460366) Escherichia coli UMN026 7157385 YP_002414016.1 CDS papH NC_011751.1 3460404 3460991 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2882856, 1357526, 2897064; Product type s : structure; minor pilin protein PapH complement(3460404..3460991) Escherichia coli UMN026 7157384 YP_002414017.1 CDS papA NC_011751.1 3461061 3461597 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10678978; Product type s : structure; P-fimbriae major subunit complement(3461061..3461597) Escherichia coli UMN026 7157388 YP_002414018.1 CDS papB NC_011751.1 3461804 3462118 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2656260, 2868893; Product type r : regulator; pap operon regulatory protein PapB complement(3461804..3462118) Escherichia coli UMN026 7157382 YP_002414019.1 CDS papI NC_011751.1 3462523 3462756 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2868893, 1357526; Product type r : regulator; pap operon regulatory protein PapI 3462523..3462756 Escherichia coli UMN026 7157383 YP_002414020.1 CDS ECUMN_3344 NC_011751.1 3464206 3464532 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS629 complement(3464206..3464532) Escherichia coli UMN026 7155272 YP_002414021.1 CDS ECUMN_3345 NC_011751.1 3464805 3464981 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3464805..3464981) Escherichia coli UMN026 7155273 YP_002414022.1 CDS ECUMN_3346 NC_011751.1 3465378 3466010 R Evidence 7 : Gene remnant; Product type pe : putative enzyme; putative transposase (fragment) complement(3465378..3466010) Escherichia coli UMN026 7155274 YP_002414023.1 CDS ECUMN_3347 NC_011751.1 3466562 3466822 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3466562..3466822 Escherichia coli UMN026 7155275 YP_002414024.1 CDS ECUMN_3348 NC_011751.1 3466864 3467424 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptional regulator 3466864..3467424 Escherichia coli UMN026 7155276 YP_002414025.1 CDS ECUMN_3349 NC_011751.1 3467434 3467892 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3467434..3467892 Escherichia coli UMN026 7155277 YP_002414026.1 CDS ECUMN_3350 NC_011751.1 3468176 3468448 R Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; Neurotensin receptor R8 complement(3468176..3468448) Escherichia coli UMN026 7155278 YP_002414027.1 CDS ECUMN_3351 NC_011751.1 3468445 3468660 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3468445..3468660) Escherichia coli UMN026 7155279 YP_002414028.1 CDS ECUMN_3352 NC_011751.1 3468664 3469047 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3468664..3469047) Escherichia coli UMN026 7155280 YP_002414029.1 CDS ECUMN_3353 NC_011751.1 3469044 3469235 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3469044..3469235) Escherichia coli UMN026 7155281 YP_002414030.1 CDS ECUMN_3354 NC_011751.1 3469323 3469643 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3469323..3469643) Escherichia coli UMN026 7155282 YP_002414031.1 CDS ECUMN_3355 NC_011751.1 3469969 3470193 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3469969..3470193) Escherichia coli UMN026 7155283 YP_002414032.1 CDS ECUMN_3356 NC_011751.1 3470427 3472517 R IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein complement(3470427..3472517) Escherichia coli UMN026 7155284 YP_002414033.1 CDS insD NC_011751.1 3473017 3473922 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(3473017..3473922) Escherichia coli UMN026 7155285 YP_002414034.1 CDS insC NC_011751.1 3473915 3474289 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type r : regulator; IS2 insertion element repressor InsA; KpLE2 phage-like element complement(3473915..3474289) Escherichia coli UMN026 7156826 YP_002414035.1 CDS ECUMN_3360 NC_011751.1 3474461 3474619 D Evidence 7 : Gene remnant; Product type pe : putative enzyme; transposase ORF A (fragment), IS3 family 3474461..3474619 Escherichia coli UMN026 7156825 YP_002414036.1 CDS ECUMN_3362 NC_011751.1 3474872 3476005 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS110 family 3474872..3476005 Escherichia coli UMN026 7155287 YP_002414037.1 CDS ECUMN_3364 NC_011751.1 3477714 3478064 R Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family complement(3477714..3478064) Escherichia coli UMN026 7155289 YP_002414038.1 CDS ECUMN_3365 NC_011751.1 3478061 3478498 R Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase complement(3478061..3478498) Escherichia coli UMN026 7155290 YP_002414039.1 CDS ECUMN_3366 NC_011751.1 3478833 3479582 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3478833..3479582) Escherichia coli UMN026 7155291 YP_002414040.1 CDS sat NC_011751.1 3479461 3483360 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Serine protease complement(3479461..3483360) Escherichia coli UMN026 7155292 YP_002414041.1 CDS ECUMN_3369 NC_011751.1 3484109 3484306 D Evidence 6 : Doubtful CDS; hypothetical protein 3484109..3484306 Escherichia coli UMN026 7157870 YP_002414042.1 CDS iutA NC_011751.1 3484292 3486571 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4313071, 6456229, 7044820, 7042696, 6749806; Product type rc : receptor; Ferric aerobactin receptor complement(3484292..3486571) Escherichia coli UMN026 7155293 YP_002414043.1 CDS iucD NC_011751.1 3486493 3487830 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3275632, 10064136; Product type e : enzyme; L-lysine 6-monooxygenase complement(3486493..3487830) Escherichia coli UMN026 7156878 YP_002414044.1 CDS iucC NC_011751.1 3487827 3489569 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme; Aerobactin siderophore biosynthesis protein complement(3487827..3489569) Escherichia coli UMN026 7156877 YP_002414045.1 CDS iucB NC_011751.1 3489569 3490516 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme; aerobactin siderophore biosynthesis protein, N(6)-hydroxylysine acetylase complement(3489569..3490516) Escherichia coli UMN026 7156876 YP_002414046.1 CDS iucA NC_011751.1 3490517 3492304 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme; aerobactin siderophore biosynthesis protein complement(3490517..3492304) Escherichia coli UMN026 7156875 YP_002414047.1 CDS shiF NC_011751.1 3492377 3493570 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411725; Product type pt : putative transporter; putative membrane transport protein, major facilitator superfamily 3492377..3493570 Escherichia coli UMN026 7156874 YP_002414048.1 CDS ECUMN_3377 NC_011751.1 3493729 3494718 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3493729..3494718) Escherichia coli UMN026 7157924 YP_002414049.1 CDS nanR NC_011751.1 3494815 3495549 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; transcriptional regulator 3494815..3495549 Escherichia coli UMN026 7155294 YP_002414050.1 CDS ECUMN_3379 NC_011751.1 3495585 3496520 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase complement(3495585..3496520) Escherichia coli UMN026 7157237 YP_002414051.1 CDS ECUMN_3380 NC_011751.1 3496570 3497688 R Evidence 4 : Homologs of previously reported genes of unknown function; N-acetylneuraminic acid mutarotase complement(3496570..3497688) Escherichia coli UMN026 7155295 YP_002414052.1 CDS ECUMN_3381 NC_011751.1 3497692 3498432 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15743943; Product type pm : putative membrane component; putative N-acetylneuraminic acid outer membrane channel protein nanC complement(3497692..3498432) Escherichia coli UMN026 7155296 YP_002414053.1 CDS ECUMN_3382 NC_011751.1 3498448 3499278 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3498448..3499278) Escherichia coli UMN026 7155297 YP_002414054.1 CDS ECUMN_3383 NC_011751.1 3499282 3500790 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; putative sialic acid transporter complement(3499282..3500790) Escherichia coli UMN026 7155298 YP_002414055.1 CDS nanK NC_011751.1 3500803 3501678 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3500803..3501678) Escherichia coli UMN026 7155299 YP_002414056.1 CDS ECUMN_3385 NC_011751.1 3501712 3502629 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3501712..3502629) Escherichia coli UMN026 7157235 YP_002414057.1 CDS ECUMN_3386 NC_011751.1 3502822 3503085 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3502822..3503085) Escherichia coli UMN026 7155300 YP_002414058.1 CDS ECUMN_3387 NC_011751.1 3503060 3503263 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3503060..3503263) Escherichia coli UMN026 7155301 YP_002414059.1 CDS ECUMN_3388 NC_011751.1 3503291 3503716 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 3503291..3503716 Escherichia coli UMN026 7155302 YP_002414060.1 CDS ECUMN_3389 NC_011751.1 3503713 3504063 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family 3503713..3504063 Escherichia coli UMN026 7155303 YP_002414061.1 CDS ECUMN_3391 NC_011751.1 3505155 3506729 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase ORF 1, IS66 family 3505155..3506729 Escherichia coli UMN026 7155305 YP_002414062.1 CDS ECUMN_3392 NC_011751.1 3506950 3507333 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3506950..3507333) Escherichia coli UMN026 7155306 YP_002414063.1 CDS ECUMN_3393 NC_011751.1 3507500 3508105 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3507500..3508105) Escherichia coli UMN026 7155307 YP_002414064.1 CDS ECUMN_3396 NC_011751.1 3510155 3510754 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3510155..3510754 Escherichia coli UMN026 7155310 YP_002414065.1 CDS ECUMN_3397 NC_011751.1 3510875 3512383 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3510875..3512383) Escherichia coli UMN026 7155311 YP_002414066.1 CDS ECUMN_3399 NC_011751.1 3513658 3514569 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3513658..3514569 Escherichia coli UMN026 7155312 YP_002414067.1 CDS flu NC_011751.1 3514897 3518022 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392470, 97257509, 99212225, 2661530, 9298646; Product type h : extrachromosomal origin; antigen 43 (Ag43) phase-variable biofilm formation autotransporter; CP4-44 prophage 3514897..3518022 Escherichia coli UMN026 7156872 YP_002414068.1 CDS ECUMN_3401 NC_011751.1 3518137 3520659 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3518137..3520659 Escherichia coli UMN026 7156417 YP_002414069.1 CDS ECUMN_3402 NC_011751.1 3520735 3521190 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3520735..3521190 Escherichia coli UMN026 7155314 YP_002414070.1 CDS ECUMN_3403 NC_011751.1 3521309 3521497 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3521309..3521497) Escherichia coli UMN026 7155315 YP_002414071.1 CDS ECUMN_3404 NC_011751.1 3521601 3522422 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3521601..3522422 Escherichia coli UMN026 7155316 YP_002414072.1 CDS yeeS NC_011751.1 3523205 3523651 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor; putative DNA repair protein; CP4-44 prophage 3523205..3523651 Escherichia coli UMN026 7155318 YP_002414073.1 CDS yeeT NC_011751.1 3523714 3523935 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3523714..3523935 Escherichia coli UMN026 7158808 YP_002414074.1 CDS ECUMN_3409 NC_011751.1 3523954 3524598 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3523954..3524598 Escherichia coli UMN026 7158810 YP_002414075.1 CDS ECUMN_3410 NC_011751.1 3524540 3525028 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3524540..3525028 Escherichia coli UMN026 7155319 YP_002414076.1 CDS ECUMN_3411 NC_011751.1 3524946 3525482 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3524946..3525482 Escherichia coli UMN026 7155320 YP_002414077.1 CDS yeeW NC_011751.1 3525479 3525967 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3525479..3525967 Escherichia coli UMN026 7155321 YP_002414078.1 CDS ECUMN_3413 NC_011751.1 3525750 3526181 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3525750..3526181 Escherichia coli UMN026 7158812 YP_002414079.1 CDS ECUMN_3414 NC_011751.1 3526263 3527111 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9987116; hypothetical protein 3526263..3527111 Escherichia coli UMN026 7155322 YP_002414080.1 CDS ECUMN_3415 NC_011751.1 3527180 3527575 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3527180..3527575 Escherichia coli UMN026 7155323 YP_002414081.1 CDS ECUMN_3416 NC_011751.1 3527568 3528308 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3527568..3528308 Escherichia coli UMN026 7155324 YP_002414082.1 CDS ECUMN_3417 NC_011751.1 3528280 3528501 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3528280..3528501 Escherichia coli UMN026 7155325 YP_002414083.1 CDS ECUMN_3418 NC_011751.1 3528933 3529088 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3528933..3529088 Escherichia coli UMN026 7155326 YP_002414084.1 CDS kpsF NC_011751.1 3529863 3530882 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8253690; Product type e : enzyme; polysialic acid capsule expression protein 3529863..3530882 Escherichia coli UMN026 7155327 YP_002414085.1 CDS kpsE NC_011751.1 3530954 3532102 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8253690; Product type t : transporter; Capsule polysaccharide export inner-membrane protein 3530954..3532102 Escherichia coli UMN026 7156912 YP_002414086.1 CDS kpsD NC_011751.1 3532123 3533802 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8021185; Product type t : transporter; polysialic acid transport protein 3532123..3533802 Escherichia coli UMN026 7156911 YP_002414087.1 CDS kpsU NC_011751.1 3533812 3534552 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3533812..3534552 Escherichia coli UMN026 7156910 YP_002414088.1 CDS kpsC NC_011751.1 3534549 3536576 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter; Capsule polysaccharide export protein 3534549..3536576 Escherichia coli UMN026 7156916 YP_002414089.1 CDS kpsS NC_011751.1 3536611 3537843 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter; Capsule polysaccharide export protein 3536611..3537843 Escherichia coli UMN026 7156909 YP_002414090.1 CDS ECUMN_3425 NC_011751.1 3538491 3538763 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3538491..3538763) Escherichia coli UMN026 7156914 YP_002414091.1 CDS ECUMN_3426 NC_011751.1 3538833 3538934 D putative integrase core domain protein (fragment) 3538833..3538934 Escherichia coli UMN026 7155328 YP_002414092.1 CDS ECUMN_3427 NC_011751.1 3539416 3540993 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10699509, 11230405; hypothetical protein complement(3539416..3540993) Escherichia coli UMN026 7155329 YP_002414093.1 CDS ECUMN_3428 NC_011751.1 3540990 3541430 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10699509, 11230405; hypothetical protein complement(3540990..3541430) Escherichia coli UMN026 7155330 YP_002414094.1 CDS ECUMN_3429 NC_011751.1 3541342 3542088 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10699509, 11230405; hypothetical protein complement(3541342..3542088) Escherichia coli UMN026 7155331 YP_002414095.1 CDS ECUMN_3430 NC_011751.1 3542126 3544627 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3542126..3544627) Escherichia coli UMN026 7155332 YP_002414096.1 CDS kpsT NC_011751.1 3544835 3545521 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 8051103, 2082146; Product type e : enzyme; polysialic acid transport ATP-binding protein complement(3544835..3545521) Escherichia coli UMN026 7155333 YP_002414097.1 CDS ECUMN_3432 NC_011751.1 3545687 3549433 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3545687..3549433) Escherichia coli UMN026 7156915 YP_002414098.1 CDS ECUMN_3433 NC_011751.1 3549453 3550445 R Evidence 4 : Homologs of previously reported genes of unknown function; putative Capsule biosynthesis protein complement(3549453..3550445) Escherichia coli UMN026 7155334 YP_002414099.1 CDS kpsM NC_011751.1 3550545 3551381 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 7715449; Product type t : transporter; polysialic acid transport protein complement(3550545..3551381) Escherichia coli UMN026 7155335 YP_002414100.1 CDS yghD NC_011751.1 3552378 3552914 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative general secretion pathway protein YghD complement(3552378..3552914) Escherichia coli UMN026 7156913 YP_002414101.1 CDS yghE NC_011751.1 3552916 3554094 R similar to general secretory pathway protein L; GspL-like protein complement(3552916..3554094) Escherichia coli UMN026 7159071 YP_002414102.1 CDS ECUMN_3437 NC_011751.1 3554091 3555068 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative type II secretion protein complement(3554091..3555068) Escherichia coli UMN026 7159072 YP_002414103.1 CDS ECUMN_3438 NC_011751.1 3555065 3555670 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3555065..3555670) Escherichia coli UMN026 7155336 YP_002414104.1 CDS ECUMN_3439 NC_011751.1 3555667 3556038 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative type II secretion protein complement(3555667..3556038) Escherichia coli UMN026 7155337 YP_002414105.1 CDS ECUMN_3440 NC_011751.1 3556035 3556598 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3556035..3556598) Escherichia coli UMN026 7155338 YP_002414106.1 CDS ECUMN_3441 NC_011751.1 3556602 3557084 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative general secretion pathway protein G (epsG-like) complement(3556602..3557084) Escherichia coli UMN026 7155339 YP_002414107.1 CDS epsF NC_011751.1 3557074 3558297 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; General secretion pathway protein F complement(3557074..3558297) Escherichia coli UMN026 7155340 YP_002414108.1 CDS epsE NC_011751.1 3558297 3559790 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein E complement(3558297..3559790) Escherichia coli UMN026 7156264 YP_002414109.1 CDS epsD NC_011751.1 3559790 3561850 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein D complement(3559790..3561850) Escherichia coli UMN026 7156263 YP_002414110.1 CDS yghF NC_011751.1 3561880 3562839 R part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; putative type II secretion protein GspC complement(3561880..3562839) Escherichia coli UMN026 7156262 YP_002414111.1 CDS yghG NC_011751.1 3562857 3563267 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3562857..3563267) Escherichia coli UMN026 7159073 YP_002414112.1 CDS pppA NC_011751.1 3563333 3564142 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98175453; Product type e : enzyme; bifunctional prepilin leader peptidase and methylase complement(3563333..3564142) Escherichia coli UMN026 7159074 YP_002414113.1 CDS yghJ NC_011751.1 3564272 3568834 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1644747; Product type lp : lipoprotein; inner membrane lipoprotein complement(3564272..3568834) Escherichia coli UMN026 7157510 YP_002414114.1 CDS ECUMN_3449 NC_011751.1 3568985 3569194 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3568985..3569194 Escherichia coli UMN026 7159075 YP_002414115.1 CDS yghK NC_011751.1 3569320 3571002 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11785976, 21178909, 11283302; Product type t : transporter; glycolate transporter complement(3569320..3571002) Escherichia coli UMN026 7155341 YP_002414116.1 CDS glcB NC_011751.1 3571357 3573528 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3571357..3573528) Escherichia coli UMN026 7155902 YP_002414117.1 CDS glcG NC_011751.1 3573550 3573954 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3573550..3573954) Escherichia coli UMN026 7156530 YP_002414118.1 CDS glcF NC_011751.1 3573959 3575182 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type c : carrier; glycolate oxidase iron-sulfur subunit complement(3573959..3575182) Escherichia coli UMN026 7156535 YP_002414119.1 CDS glcE NC_011751.1 3575193 3576245 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme; glycolate oxidase FAD binding subunit complement(3575193..3576245) Escherichia coli UMN026 7156534 YP_002414120.1 CDS glcD NC_011751.1 3576245 3577744 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme; glycolate oxidase subunit GlcD complement(3576245..3577744) Escherichia coli UMN026 7156533 YP_002414121.1 CDS glcC NC_011751.1 3577995 3578759 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 9880556, 8606183; Product type r : regulator; DNA-binding transcriptional regulator GlcC 3577995..3578759 Escherichia coli UMN026 7156532 YP_002414122.1 CDS yghO NC_011751.1 3578766 3579908 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3578766..3579908) Escherichia coli UMN026 7156531 YP_002414123.1 CDS ECUMN_3458 NC_011751.1 3580253 3582934 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3580253..3582934 Escherichia coli UMN026 7159077 YP_002414124.1 CDS ECUMN_3460 NC_011751.1 3582966 3583214 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3582966..3583214 Escherichia coli UMN026 7155342 YP_002414125.1 CDS ECUMN_3461 NC_011751.1 3583214 3584386 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 8-amino-7-oxononanoate synthase 3583214..3584386 Escherichia coli UMN026 7155343 YP_002414126.1 CDS ECUMN_3464 NC_011751.1 3585497 3586567 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3585497..3586567) Escherichia coli UMN026 7155346 YP_002414127.1 CDS ECUMN_3465 NC_011751.1 3586598 3587161 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(3586598..3587161) Escherichia coli UMN026 7155347 YP_002414128.1 CDS ECUMN_3466 NC_011751.1 3587170 3587994 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3587170..3587994) Escherichia coli UMN026 7155348 YP_002414129.1 CDS ECUMN_3467 NC_011751.1 3587994 3589343 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein complement(3587994..3589343) Escherichia coli UMN026 7155349 YP_002414130.1 CDS yghR NC_011751.1 3589389 3590147 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3589389..3590147) Escherichia coli UMN026 7155350 YP_002414131.1 CDS yghS NC_011751.1 3590179 3590892 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3590179..3590892) Escherichia coli UMN026 7159078 YP_002414132.1 CDS yghT NC_011751.1 3591066 3591758 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3591066..3591758 Escherichia coli UMN026 7159079 YP_002414133.1 CDS pitB NC_011751.1 3591807 3593306 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21336523, 21382172, 7775463; Product type t : transporter; phosphate transporter complement(3591807..3593306) Escherichia coli UMN026 7159080 YP_002414134.1 CDS gss NC_011751.1 3593598 3595457 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3593598..3595457) Escherichia coli UMN026 7157469 YP_002414135.1 CDS yghU NC_011751.1 3595662 3596528 D YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 3595662..3596528 Escherichia coli UMN026 7156620 YP_002414136.1 CDS hybG NC_011751.1 3596760 3597008 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 94292472, 8021226; Product type pf : putative factor; hydrogenase 2 accessory protein HypG complement(3596760..3597008) Escherichia coli UMN026 7159081 YP_002414137.1 CDS hybF NC_011751.1 3597021 3597362 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3597021..3597362) Escherichia coli UMN026 7156746 YP_002414138.1 CDS hybE NC_011751.1 3597355 3597843 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292472, 8021226; Product type f : factor; hydrogenase 2-specific chaperone complement(3597355..3597843) Escherichia coli UMN026 7156745 YP_002414139.1 CDS hybD NC_011751.1 3597836 3598330 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3597836..3598330) Escherichia coli UMN026 7156744 YP_002414140.1 CDS hybC NC_011751.1 3598330 3600033 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3598330..3600033) Escherichia coli UMN026 7156743 YP_002414141.1 CDS hybB NC_011751.1 3600030 3601208 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit complement(3600030..3601208) Escherichia coli UMN026 7156742 YP_002414142.1 CDS hybA NC_011751.1 3601198 3602184 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3601198..3602184) Escherichia coli UMN026 7156741 YP_002414143.1 CDS hybO NC_011751.1 3602187 3603305 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3602187..3603305) Escherichia coli UMN026 7156740 YP_002414144.1 CDS ECUMN_3482 NC_011751.1 3603312 3603497 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3603312..3603497) Escherichia coli UMN026 7156747 YP_002414145.1 CDS yghW NC_011751.1 3603494 3603781 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3603494..3603781) Escherichia coli UMN026 7155351 YP_002414146.1 CDS ECUMN_3484 NC_011751.1 3603900 3604826 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3603900..3604826) Escherichia coli UMN026 7159082 YP_002414147.1 CDS yghZ NC_011751.1 3604944 3605984 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12583903; Product type e : enzyme; aldo-keto reductase 3604944..3605984 Escherichia coli UMN026 7155352 YP_002414148.1 CDS yqhA NC_011751.1 3606024 3606518 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3606024..3606518) Escherichia coli UMN026 7159083 YP_002414149.1 CDS yghA NC_011751.1 3606709 3607593 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; oxidoreductase 3606709..3607593 Escherichia coli UMN026 7159618 YP_002414150.1 CDS ECUMN_3488 NC_011751.1 3607703 3608212 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group complement(3607703..3608212) Escherichia coli UMN026 7159069 YP_002414151.1 CDS ECUMN_3489 NC_011751.1 3608118 3608306 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3608118..3608306) Escherichia coli UMN026 7155353 YP_002414152.1 CDS exbD NC_011751.1 3608576 3609001 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3608576..3609001) Escherichia coli UMN026 7155354 YP_002414153.1 CDS exbB NC_011751.1 3609008 3609742 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3609008..3609742) Escherichia coli UMN026 7156288 YP_002414154.1 CDS metC NC_011751.1 3609994 3611181 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3609994..3611181 Escherichia coli UMN026 7156287 YP_002414155.1 CDS yghB NC_011751.1 3611321 3611980 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3611321..3611980 Escherichia coli UMN026 7157102 YP_002414156.1 CDS yqhC NC_011751.1 3612020 3612976 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3612020..3612976) Escherichia coli UMN026 7159070 YP_002414157.1 CDS yqhD NC_011751.1 3613113 3614276 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15327949; Product type e : enzyme; alcohol dehydrogenase 3613113..3614276 Escherichia coli UMN026 7159619 YP_002414158.1 CDS dkgA NC_011751.1 3614381 3615208 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3614381..3615208 Escherichia coli UMN026 7159620 YP_002414159.1 CDS yqhG NC_011751.1 3615408 3616334 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3615408..3616334 Escherichia coli UMN026 7156175 YP_002414160.1 CDS yqhH NC_011751.1 3616385 3616642 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative outer membrane lipoprotein 3616385..3616642 Escherichia coli UMN026 7159621 YP_002414161.1 CDS ygiQ NC_011751.1 3616685 3618904 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3616685..3618904) Escherichia coli UMN026 7159622 YP_002414162.1 CDS sufI NC_011751.1 3619015 3620427 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88314889, 1557036, 9298646; Product type r : regulator; repressor protein for FtsI complement(3619015..3620427) Escherichia coli UMN026 7159091 YP_002414163.1 CDS plsC NC_011751.1 3620502 3621239 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212294, 1557036; Product type e : enzyme; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3620502..3621239) Escherichia coli UMN026 7158007 YP_002414164.1 CDS ECUMN_3502 NC_011751.1 3621287 3621442 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3621287..3621442) Escherichia coli UMN026 7157473 YP_002414165.1 CDS parC NC_011751.1 3621473 3623731 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3621473..3623731) Escherichia coli UMN026 7155355 YP_002414166.1 CDS ygiS NC_011751.1 3623869 3625476 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein complement(3623869..3625476) Escherichia coli UMN026 7157392 YP_002414167.1 CDS ygiT NC_011751.1 3625609 3626004 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3625609..3626004) Escherichia coli UMN026 7159092 YP_002414168.1 CDS mqsR NC_011751.1 3626006 3626302 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16352847, 12952533, 14727089; Product type r : regulator; motility quorum-sensing regulator complement(3626006..3626302) Escherichia coli UMN026 7159093 YP_002414169.1 CDS ygiV NC_011751.1 3626507 3626989 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(3626507..3626989) Escherichia coli UMN026 7157171 YP_002414170.1 CDS ygiW NC_011751.1 3627042 3627434 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein complement(3627042..3627434) Escherichia coli UMN026 7159094 YP_002414171.1 CDS qseB NC_011751.1 3627586 3628245 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3627586..3628245 Escherichia coli UMN026 7159095 YP_002414172.1 CDS qseC NC_011751.1 3628242 3629591 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21927389; Product type r : regulator; sensor protein QseC 3628242..3629591 Escherichia coli UMN026 7157610 YP_002414173.1 CDS ygiZ NC_011751.1 3629637 3629969 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3629637..3629969) Escherichia coli UMN026 7157611 YP_002414174.1 CDS mdaB NC_011751.1 3630297 3630878 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96004656, 96217538; Product type c : carrier; NADPH quinone reductase 3630297..3630878 Escherichia coli UMN026 7159096 YP_002414175.1 CDS ygiN NC_011751.1 3630909 3631223 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10493123, 9298646, 9600841, 9868784; Product type e : enzyme; quinol monooxygenase 3630909..3631223 Escherichia coli UMN026 7157068 YP_002414176.1 CDS parE NC_011751.1 3631271 3633163 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3631271..3633163) Escherichia coli UMN026 7159089 YP_002414177.1 CDS yqiA NC_011751.1 3633192 3633773 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(3633192..3633773) Escherichia coli UMN026 7157393 YP_002414178.1 CDS cpdA NC_011751.1 3633773 3634600 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96411758; Product type e : enzyme; cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3633773..3634600) Escherichia coli UMN026 7159623 YP_002414179.1 CDS yqiB NC_011751.1 3634625 3635047 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(3634625..3635047) Escherichia coli UMN026 7156000 YP_002414180.1 CDS nudF NC_011751.1 3635048 3635677 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF complement(3635048..3635677) Escherichia coli UMN026 7159624 YP_002414181.1 CDS tolC NC_011751.1 3635882 3637363 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3635882..3637363 Escherichia coli UMN026 7157320 YP_002414182.1 CDS ygiB NC_011751.1 3637607 3638182 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3637607..3638182 Escherichia coli UMN026 7158083 YP_002414183.1 CDS ygiC NC_011751.1 3638188 3639348 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3638188..3639348 Escherichia coli UMN026 7159084 YP_002414184.1 CDS assT NC_011751.1 3639833 3641629 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 11534764; Product type e : enzyme; arylsulfate sulfotransferase 3639833..3641629 Escherichia coli UMN026 7159085 YP_002414185.1 CDS dsbA NC_011751.1 3641647 3642315 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 10600454; Product type e : enzyme; Thiol:disulfide interchange protein dsbA 3641647..3642315 Escherichia coli UMN026 7155821 YP_002414186.1 CDS ECUMN_3525 NC_011751.1 3642330 3643001 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10600454; Product type pe : putative enzyme; putative disulfide oxidoreductase 3642330..3643001 Escherichia coli UMN026 7156201 YP_002414187.1 CDS zupT NC_011751.1 3643047 3643862 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3643047..3643862) Escherichia coli UMN026 7155356 YP_002414188.1 CDS ygiE NC_011751.1 3643978 3644751 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790762, 1314093; Product type t : transporter; zinc transporter ZupT 3643978..3644751 Escherichia coli UMN026 7159695 YP_002414189.1 CDS ECUMN_3528 NC_011751.1 3644809 3645003 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3644809..3645003) Escherichia coli UMN026 7159086 YP_002414190.1 CDS ribB NC_011751.1 3645241 3645894 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3645241..3645894) Escherichia coli UMN026 7155357 YP_002414191.1 CDS yqiC NC_011751.1 3646208 3646567 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3646208..3646567 Escherichia coli UMN026 7157683 YP_002414192.1 CDS glgS NC_011751.1 3646602 3646802 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3646602..3646802) Escherichia coli UMN026 7159625 YP_002414193.1 CDS yqiJ NC_011751.1 3647071 3647700 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3647071..3647700 Escherichia coli UMN026 7156541 YP_002414194.1 CDS yqiK NC_011751.1 3647727 3649388 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3647727..3649388 Escherichia coli UMN026 7159626 YP_002414195.1 CDS rfaE NC_011751.1 3650184 3651617 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3650184..3651617) Escherichia coli UMN026 7157850 YP_002414196.1 CDS glnE NC_011751.1 3651665 3654505 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3651665..3654505) Escherichia coli UMN026 7157653 YP_002414197.1 CDS ygiF NC_011751.1 3654528 3655829 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8412694; Product type pe : putative enzyme; putative adenylate cyclase complement(3654528..3655829) Escherichia coli UMN026 7156551 YP_002414198.1 CDS ECUMN_3537 NC_011751.1 3655846 3656052 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3655846..3656052) Escherichia coli UMN026 7159087 YP_002414199.1 CDS htrG NC_011751.1 3656071 3656691 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11274153; Product type pr : putative regulator; putative signal transduction protein 3656071..3656691 Escherichia coli UMN026 7155358 YP_002414200.1 CDS cca NC_011751.1 3656755 3657993 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3656755..3657993 Escherichia coli UMN026 7156730 YP_002414201.1 CDS bacA NC_011751.1 3658084 3658905 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3658084..3658905) Escherichia coli UMN026 7155925 YP_002414202.1 CDS folB NC_011751.1 3658996 3659364 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3658996..3659364) Escherichia coli UMN026 7155848 YP_002414203.1 CDS plsY NC_011751.1 3659469 3660086 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 3659469..3660086 Escherichia coli UMN026 7156424 YP_002414204.1 CDS ygiP NC_011751.1 3660099 3661031 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3660099..3661031) Escherichia coli UMN026 7157475 YP_002414205.1 CDS ttdA NC_011751.1 3661238 3662149 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3661238..3662149 Escherichia coli UMN026 7159090 YP_002414206.1 CDS ttdB NC_011751.1 3662146 3662751 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3662146..3662751 Escherichia coli UMN026 7158136 YP_002414207.1 CDS ygjE NC_011751.1 3662800 3664263 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative tartrate:succinate antiporter 3662800..3664263 Escherichia coli UMN026 7158137 YP_002414208.1 CDS gcp NC_011751.1 3664306 3665319 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(3664306..3665319) Escherichia coli UMN026 7159097 YP_002414209.1 CDS rpsU NC_011751.1 3665557 3665772 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3665557..3665772 Escherichia coli UMN026 7156519 YP_002414210.1 CDS dnaG NC_011751.1 3665883 3667628 D synthesizes RNA primers at the replication forks; DNA primase 3665883..3667628 Escherichia coli UMN026 7157787 YP_002414211.1 CDS rpoD NC_011751.1 3667823 3669664 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3667823..3669664 Escherichia coli UMN026 7156187 YP_002414212.1 CDS ygjF NC_011751.1 3669743 3670249 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20412902, 99453007, 6269063, 7567469, 8878487, 9489705; Product type e : enzyme; G/U mismatch-specific DNA glycosylase complement(3669743..3670249) Escherichia coli UMN026 7157760 YP_002414213.1 CDS yqjH NC_011751.1 3670503 3671267 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative siderophore interacting protein complement(3670503..3671267) Escherichia coli UMN026 7155589 YP_002414214.1 CDS yqjI NC_011751.1 3671544 3672167 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 3671544..3672167 Escherichia coli UMN026 7159635 YP_002414215.1 CDS aer NC_011751.1 3672272 3673792 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 9380671, 9643537, 9190831; Product type r : regulator; fused signal transducer/methyl accepting chemotaxis protein complement(3672272..3673792) Escherichia coli UMN026 7159636 YP_002414216.1 CDS ygjG NC_011751.1 3674183 3675589 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3674183..3675589 Escherichia coli UMN026 7155706 YP_002414217.1 CDS ygjH NC_011751.1 3675631 3675963 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11101501; hypothetical protein complement(3675631..3675963) Escherichia coli UMN026 7159099 YP_002414218.1 CDS ebgR NC_011751.1 3676182 3677165 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89128452, 2515108, 3939708; Product type r : regulator; DNA-binding transcriptional repressor EbgR 3676182..3677165 Escherichia coli UMN026 7159100 YP_002414219.1 CDS ebgA NC_011751.1 3677349 3680441 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3677349..3680441 Escherichia coli UMN026 7156221 YP_002414220.1 CDS ebgC NC_011751.1 3680438 3680887 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3680438..3680887 Escherichia coli UMN026 7156219 YP_002414221.1 CDS ygjI NC_011751.1 3680950 3682383 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3680950..3682383 Escherichia coli UMN026 7156220 YP_002414222.1 CDS ygjJ NC_011751.1 3682517 3683587 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3682517..3683587 Escherichia coli UMN026 7159101 YP_002414223.1 CDS ygjK NC_011751.1 3683604 3685955 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213393; Product type pe : putative enzyme; putative glycosyl hydrolase 3683604..3685955 Escherichia coli UMN026 7159102 YP_002414224.1 CDS fadH NC_011751.1 3686126 3688144 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12840019, 89380266; Product type e : enzyme; 2,4-dienoyl-CoA reductase, NADH and FMN-linked 3686126..3688144 Escherichia coli UMN026 7159103 YP_002414225.1 CDS ygjM NC_011751.1 3688189 3688605 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3688189..3688605) Escherichia coli UMN026 7156306 YP_002414226.1 CDS ygjN NC_011751.1 3688602 3688916 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3688602..3688916) Escherichia coli UMN026 7159104 YP_002414227.1 CDS ygjO NC_011751.1 3689201 3690337 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase small domain complement(3689201..3690337) Escherichia coli UMN026 7159105 YP_002414228.1 CDS ygjP NC_011751.1 3690422 3690925 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal dependent hydrolase 3690422..3690925 Escherichia coli UMN026 7159106 YP_002414229.1 CDS ygjQ NC_011751.1 3691002 3691685 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative thioredoxin-like 3691002..3691685 Escherichia coli UMN026 7159107 YP_002414230.1 CDS ygjR NC_011751.1 3691746 3692750 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)-binding dehydrogenase 3691746..3692750 Escherichia coli UMN026 7159108 YP_002414231.1 CDS alx NC_011751.1 3693033 3693998 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12107143, 2108134; Product type pm : putative membrane component; hypothetical protein 3693033..3693998 Escherichia coli UMN026 7157971 YP_002414232.1 CDS sstT NC_011751.1 3694614 3695858 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3694614..3695858 Escherichia coli UMN026 7155732 YP_002414233.1 CDS ygjV NC_011751.1 3695863 3696414 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3695863..3696414) Escherichia coli UMN026 7157990 YP_002414234.1 CDS uxaA NC_011751.1 3696497 3697984 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4570160, 83114543, 3038546; Product type e : enzyme; altronate hydrolase complement(3696497..3697984) Escherichia coli UMN026 7159110 YP_002414235.1 CDS uxaC NC_011751.1 3697999 3699411 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3697999..3699411) Escherichia coli UMN026 7158203 YP_002414236.1 CDS exuT NC_011751.1 3699774 3701192 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83218546, 98190790; Product type t : transporter; hexuronate transporter 3699774..3701192 Escherichia coli UMN026 7158205 YP_002414237.1 CDS exuR NC_011751.1 3701322 3702098 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3701322..3702098 Escherichia coli UMN026 7156292 YP_002414238.1 CDS yqjA NC_011751.1 3702443 3703105 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3702443..3703105 Escherichia coli UMN026 7156291 YP_002414239.1 CDS yqjB NC_011751.1 3703109 3703492 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein 3703109..3703492 Escherichia coli UMN026 7159628 YP_002414240.1 CDS yqjC NC_011751.1 3703639 3704007 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3703639..3704007 Escherichia coli UMN026 7159629 YP_002414241.1 CDS yqjD NC_011751.1 3704045 3704350 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3704045..3704350 Escherichia coli UMN026 7159630 YP_002414242.1 CDS yqjE NC_011751.1 3704353 3704757 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3704353..3704757 Escherichia coli UMN026 7159631 YP_002414243.1 CDS yqjK NC_011751.1 3704747 3705046 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3704747..3705046 Escherichia coli UMN026 7159632 YP_002414244.1 CDS yqjF NC_011751.1 3705233 3705625 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative quinol oxidase subunit 3705233..3705625 Escherichia coli UMN026 7159637 YP_002414245.1 CDS yqjG NC_011751.1 3705695 3706681 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8478329; Product type e : enzyme; S-transferase 3705695..3706681 Escherichia coli UMN026 7159633 YP_002414246.1 CDS yhaH NC_011751.1 3706973 3707338 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3706973..3707338 Escherichia coli UMN026 7159634 YP_002414247.1 CDS yhaI NC_011751.1 3707580 3707936 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3707580..3707936 Escherichia coli UMN026 7159113 YP_002414248.1 CDS insA NC_011751.1 3708026 3708301 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 3708026..3708301 Escherichia coli UMN026 7159114 YP_002414249.1 CDS insB NC_011751.1 3708220 3708723 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage 3708220..3708723 Escherichia coli UMN026 7156814 YP_002414250.1 CDS yhaJ NC_011751.1 3708764 3709660 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3708764..3709660) Escherichia coli UMN026 7156819 YP_002414251.1 CDS yhaK NC_011751.1 3709765 3710466 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative pirin-like protein 3709765..3710466 Escherichia coli UMN026 7159115 YP_002414252.1 CDS yhaL NC_011751.1 3710489 3710653 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3710489..3710653 Escherichia coli UMN026 7159116 YP_002414253.1 CDS yhaM NC_011751.1 3710786 3712096 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3710786..3712096) Escherichia coli UMN026 7159117 YP_002414254.1 CDS yhaO NC_011751.1 3712124 3713392 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(3712124..3713392) Escherichia coli UMN026 7159118 YP_002414255.1 CDS tdcG NC_011751.1 3713731 3715095 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme; L-serine dehydratase 3 complement(3713731..3715095) Escherichia coli UMN026 7159119 YP_002414256.1 CDS tdcF NC_011751.1 3715167 3715556 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12777779, 9484901; Product type e : enzyme; hypothetical protein complement(3715167..3715556) Escherichia coli UMN026 7158041 YP_002414257.1 CDS tdcE NC_011751.1 3715570 3717864 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase complement(3715570..3717864) Escherichia coli UMN026 7158040 YP_002414258.1 CDS tdcD NC_011751.1 3717898 3719118 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3717898..3719118) Escherichia coli UMN026 7158039 YP_002414259.1 CDS tdcC NC_011751.1 3719132 3720463 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3719132..3720463) Escherichia coli UMN026 7158038 YP_002414260.1 CDS tdcB NC_011751.1 3720485 3721474 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3720485..3721474) Escherichia coli UMN026 7158037 YP_002414261.1 CDS tdcA NC_011751.1 3721573 3722511 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3721573..3722511) Escherichia coli UMN026 7158036 YP_002414262.1 CDS tdcR NC_011751.1 3722688 3723044 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3722688..3723044 Escherichia coli UMN026 7158035 YP_002414263.1 CDS yhaB NC_011751.1 3723300 3723839 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3723300..3723839 Escherichia coli UMN026 7158042 YP_002414264.1 CDS yhaC NC_011751.1 3723861 3725048 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1705543, 2573820, 2660107, 6351058; hypothetical protein 3723861..3725048 Escherichia coli UMN026 7159111 YP_002414265.1 CDS garK NC_011751.1 3725565 3726791 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 69151449, 9772162; Product type e : enzyme; glycerate kinase I complement(3725565..3726791) Escherichia coli UMN026 7157717 YP_002414266.1 CDS garR NC_011751.1 3726807 3727697 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3726807..3727697) Escherichia coli UMN026 7156506 YP_002414267.1 CDS garL NC_011751.1 3727727 3728497 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3727727..3728497) Escherichia coli UMN026 7156509 YP_002414268.1 CDS garP NC_011751.1 3728513 3729847 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10762278, 9772162; Product type pt : putative transporter; putative (D)-galactarate transporter complement(3728513..3729847) Escherichia coli UMN026 7156507 YP_002414269.1 CDS garD NC_011751.1 3730222 3731793 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 66096392, 81027430, 9772162, 10762278, 2407727; Product type e : enzyme; (D)-galactarate dehydrogenase 3730222..3731793 Escherichia coli UMN026 7156508 YP_002414270.1 CDS sohA NC_011751.1 3731942 3732277 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 3731942..3732277 Escherichia coli UMN026 7156505 YP_002414271.1 CDS yhaV NC_011751.1 3732277 3732741 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3732277..3732741 Escherichia coli UMN026 7157948 YP_002414272.1 CDS agaR NC_011751.1 3732796 3733605 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3732796..3733605) Escherichia coli UMN026 7159120 YP_002414273.1 CDS kbaZ NC_011751.1 3733854 3735134 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 20392444, 10931310, 8932697; Product type e : enzyme; tagatose 6-phosphate aldolase 1, kbaZ subunit 3733854..3735134 Escherichia coli UMN026 7155713 YP_002414274.1 CDS agaV NC_011751.1 3735157 3735630 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3735157..3735630 Escherichia coli UMN026 7156884 YP_002414275.1 CDS ECUMN_3616 NC_011751.1 3735641 3736420 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIC component of PTS 3735641..3736420 Escherichia coli UMN026 7155715 YP_002414276.1 CDS ECUMN_3617 NC_011751.1 3736404 3737288 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative hexose/hexosamine family PTS permease IID component 3736404..3737288 Escherichia coli UMN026 7155359 YP_002414277.1 CDS ECUMN_3618 NC_011751.1 3737306 3737740 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase system enzyme subunit (N-acetyl-galactosamine / galactosamine PTS system enzyme IIA component) 3737306..3737740 Escherichia coli UMN026 7155360 YP_002414278.1 CDS agaA NC_011751.1 3737716 3738870 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; N-acetylglucosamine-6-phosphate deacetylase 3737716..3738870 Escherichia coli UMN026 7155361 YP_002414279.1 CDS agaS NC_011751.1 3739220 3740374 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689210, 9697096, 14731281, 8932697; Product type e : enzyme; tagatose-6-phosphate ketose/aldose isomerase 3739220..3740374 Escherichia coli UMN026 7155708 YP_002414280.1 CDS kbaY NC_011751.1 3740387 3741247 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3740387..3741247 Escherichia coli UMN026 7155714 YP_002414281.1 CDS agaB NC_011751.1 3741414 3741890 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3741414..3741890 Escherichia coli UMN026 7156883 YP_002414282.1 CDS agaC NC_011751.1 3741929 3742732 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3741929..3742732 Escherichia coli UMN026 7155709 YP_002414283.1 CDS agaD NC_011751.1 3742722 3743513 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3742722..3743513 Escherichia coli UMN026 7155710 YP_002414284.1 CDS agaI NC_011751.1 3743514 3744281 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10931310; Product type e : enzyme; galactosamine-6-phosphate isomerase 3743514..3744281 Escherichia coli UMN026 7155711 YP_002414285.1 CDS yraL NC_011751.1 3744331 3745194 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase complement(3744331..3745194) Escherichia coli UMN026 7155712 YP_002414286.1 CDS yraM NC_011751.1 3745259 3747295 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3745259..3747295 Escherichia coli UMN026 7159638 YP_002414287.1 CDS yraN NC_011751.1 3747253 3747648 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3747253..3747648 Escherichia coli UMN026 7159639 YP_002414288.1 CDS yraO NC_011751.1 3747668 3748258 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3747668..3748258 Escherichia coli UMN026 7159640 YP_002414289.1 CDS ecfH NC_011751.1 3748268 3748843 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein 3748268..3748843 Escherichia coli UMN026 7159641 YP_002414290.1 CDS yraQ NC_011751.1 3748965 3750005 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease complement(3748965..3750005) Escherichia coli UMN026 7156223 YP_002414291.1 CDS yraR NC_011751.1 3750078 3750713 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleoside-diphosphate-sugar epimerase complement(3750078..3750713) Escherichia coli UMN026 7159642 YP_002414292.1 CDS yhbO NC_011751.1 3750841 3751359 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative intracellular protease 3750841..3751359 Escherichia coli UMN026 7159643 YP_002414293.1 CDS yhbP NC_011751.1 3751339 3751782 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3751339..3751782) Escherichia coli UMN026 7159125 YP_002414294.1 CDS yhbQ NC_011751.1 3751833 3752135 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; GIY-YIG nuclease superfamily protein 3751833..3752135 Escherichia coli UMN026 7159126 YP_002414295.1 CDS yhbS NC_011751.1 3752122 3752625 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase complement(3752122..3752625) Escherichia coli UMN026 7159127 YP_002414296.1 CDS yhbT NC_011751.1 3752619 3753143 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative lipid carrier protein complement(3752619..3753143) Escherichia coli UMN026 7159128 YP_002414297.1 CDS yhbU NC_011751.1 3753352 3754347 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; peptidase (collagenase-like) 3753352..3754347 Escherichia coli UMN026 7159129 YP_002414298.1 CDS yhbV NC_011751.1 3754356 3755234 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; protease 3754356..3755234 Escherichia coli UMN026 7159130 YP_002414299.1 CDS yhbW NC_011751.1 3755315 3756322 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3755315..3756322 Escherichia coli UMN026 7159131 YP_002414300.1 CDS ECUMN_3641 NC_011751.1 3756300 3757019 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3756300..3757019) Escherichia coli UMN026 7159132 YP_002414301.1 CDS ECUMN_3642 NC_011751.1 3757177 3757707 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; putative cytoplasmic protein 3757177..3757707 Escherichia coli UMN026 7155362 YP_002414302.1 CDS mtr NC_011751.1 3757768 3759012 R tryptophan transporter of high affinity; tryptophan permease complement(3757768..3759012) Escherichia coli UMN026 7155363 YP_002414303.1 CDS deaD NC_011751.1 3759166 3761133 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3759166..3761133) Escherichia coli UMN026 7157197 YP_002414304.1 CDS nlpI NC_011751.1 3761247 3762131 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3761247..3762131) Escherichia coli UMN026 7156133 YP_002414305.1 CDS pnp NC_011751.1 3762240 3764444 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87083499, 91198209, 99234021, 99340204, 2432069, 3005122, 6382163, 9008164, 9298646; Product type e : enzyme; polynucleotide phosphorylase/polyadenylase complement(3762240..3764444) Escherichia coli UMN026 7157290 YP_002414306.1 CDS rpsO NC_011751.1 3764622 3764891 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3764622..3764891) Escherichia coli UMN026 7157972 YP_002414307.1 CDS truB NC_011751.1 3765040 3765984 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3765040..3765984) Escherichia coli UMN026 7157781 YP_002414308.1 CDS rbfA NC_011751.1 3765984 3766385 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3765984..3766385) Escherichia coli UMN026 7158126 YP_002414309.1 CDS infB NC_011751.1 3766544 3769216 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3766544..3769216) Escherichia coli UMN026 7157620 YP_002414310.1 CDS nusA NC_011751.1 3769241 3770728 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3769241..3770728) Escherichia coli UMN026 7156812 YP_002414311.1 CDS yhbC NC_011751.1 3770756 3771208 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3770756..3771208) Escherichia coli UMN026 7157338 YP_002414312.1 CDS argG NC_011751.1 3771839 3773182 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3771839..3773182 Escherichia coli UMN026 7155622 YP_002414313.1 CDS yhbX NC_011751.1 3773190 3774815 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase complement(3773190..3774815) Escherichia coli UMN026 7155773 YP_002414314.1 CDS secG NC_011751.1 3775375 3775707 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20194819, 21125563, 9020118, 94074540, 9564033, 9644254, 9829959, 99298179, 7556084, 8034620, 8045257, 8244950, 8253068; Product type t : transporter; preprotein translocase subunit SecG complement(3775375..3775707) Escherichia coli UMN026 7155621 YP_002414315.1 CDS glmM NC_011751.1 3775935 3777272 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3775935..3777272) Escherichia coli UMN026 7157890 YP_002414316.1 CDS folP NC_011751.1 3777265 3778113 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3777265..3778113) Escherichia coli UMN026 7156545 YP_002414317.1 CDS hflB NC_011751.1 3778203 3780137 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3778203..3780137) Escherichia coli UMN026 7156430 YP_002414318.1 CDS rrmJ NC_011751.1 3780237 3780866 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J complement(3780237..3780866) Escherichia coli UMN026 7156459 YP_002414319.1 CDS yhbY NC_011751.1 3780992 3781285 D RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3780992..3781285 Escherichia coli UMN026 7157790 YP_002414320.1 CDS greA NC_011751.1 3781441 3781917 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3781441..3781917) Escherichia coli UMN026 7159134 YP_002414321.1 CDS dacB NC_011751.1 3782165 3783598 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3782165..3783598 Escherichia coli UMN026 7156609 YP_002414322.1 CDS obgE NC_011751.1 3783638 3784810 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3783638..3784810) Escherichia coli UMN026 7156100 YP_002414323.1 CDS yhbE NC_011751.1 3784826 3785791 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3784826..3785791) Escherichia coli UMN026 7157342 YP_002414324.1 CDS rpmA NC_011751.1 3785918 3786175 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3785918..3786175) Escherichia coli UMN026 7159122 YP_002414325.1 CDS rplU NC_011751.1 3786196 3786507 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91088242, 94146411, 10094780, 387076, 8312607; Product type s : structure; 50S ribosomal protein L21 complement(3786196..3786507) Escherichia coli UMN026 7157748 YP_002414326.1 CDS ispB NC_011751.1 3786766 3787737 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94311902, 97284515, 2670911, 8037730, 8312607; Product type e : enzyme; octaprenyl diphosphate synthase 3786766..3787737 Escherichia coli UMN026 7157743 YP_002414327.1 CDS sfsB NC_011751.1 3787964 3788242 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3787964..3788242 Escherichia coli UMN026 7156863 YP_002414328.1 CDS murA NC_011751.1 3788290 3789549 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3788290..3789549) Escherichia coli UMN026 7157910 YP_002414329.1 CDS yrbA NC_011751.1 3789604 3789858 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3789604..3789858) Escherichia coli UMN026 7157201 YP_002414330.1 CDS yrbB NC_011751.1 3790017 3790310 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3790017..3790310) Escherichia coli UMN026 7159644 YP_002414331.1 CDS yrbC NC_011751.1 3790310 3790945 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein complement(3790310..3790945) Escherichia coli UMN026 7159645 YP_002414332.1 CDS yrbD NC_011751.1 3790964 3791515 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein complement(3790964..3791515) Escherichia coli UMN026 7159646 YP_002414333.1 CDS yrbE NC_011751.1 3791520 3792302 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein complement(3791520..3792302) Escherichia coli UMN026 7159647 YP_002414334.1 CDS yrbF NC_011751.1 3792310 3793119 R ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF complement(3792310..3793119) Escherichia coli UMN026 7159648 YP_002414335.1 CDS yrbG NC_011751.1 3793329 3794306 D YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 3793329..3794306 Escherichia coli UMN026 7159649 YP_002414336.1 CDS kdsD NC_011751.1 3794320 3795306 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12805358; Product type e : enzyme; D-arabinose 5-phosphate isomerase 3794320..3795306 Escherichia coli UMN026 7159650 YP_002414337.1 CDS kdsC NC_011751.1 3795327 3795893 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3795327..3795893 Escherichia coli UMN026 7156898 YP_002414338.1 CDS yrbK NC_011751.1 3795890 3796465 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3795890..3796465 Escherichia coli UMN026 7156897 YP_002414339.1 CDS lptA NC_011751.1 3796434 3796991 D LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3796434..3796991 Escherichia coli UMN026 7159651 YP_002414340.1 CDS lptB NC_011751.1 3796998 3797723 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7876255, 9298646, 17056748; Product type pt : putative transporter; putative ABC transporter ATP-binding protein YhbG 3796998..3797723 Escherichia coli UMN026 7157007 YP_002414341.1 CDS rpoN NC_011751.1 3797771 3799204 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3797771..3799204 Escherichia coli UMN026 7157008 YP_002414342.1 CDS yhbH NC_011751.1 3799227 3799514 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 3799227..3799514 Escherichia coli UMN026 7157763 YP_002414343.1 CDS ptsN NC_011751.1 3799632 3800123 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88212176, 90136533, 90274974, 95020584, 95181483, 7876255, 8025669, 8444818, 9636714; Product type t : transporter; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3799632..3800123 Escherichia coli UMN026 7159123 YP_002414344.1 CDS yhbJ NC_011751.1 3800169 3801023 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3800169..3801023 Escherichia coli UMN026 7157570 YP_002414345.1 CDS npr NC_011751.1 3801020 3801292 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 95181483, 7876255, 8025669; Product type t : transporter; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3801020..3801292 Escherichia coli UMN026 7159124 YP_002414346.1 CDS yrbL NC_011751.1 3801505 3802137 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 89083480; hypothetical protein 3801505..3802137 Escherichia coli UMN026 7157297 YP_002414347.1 CDS mtgA NC_011751.1 3802134 3802862 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3802134..3802862) Escherichia coli UMN026 7159652 YP_002414348.1 CDS elbB NC_011751.1 3802859 3803512 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92246944, 98269038, 1575737, 9603997; Product type pe : putative enzyme; isoprenoid biosynthesis protein complement(3802859..3803512) Escherichia coli UMN026 7157190 YP_002414349.1 CDS arcB NC_011751.1 3803742 3806078 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3803742..3806078) Escherichia coli UMN026 7157854 YP_002414350.1 CDS yhcC NC_011751.1 3806174 3807103 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Fe-S oxidoreductase complement(3806174..3807103) Escherichia coli UMN026 7155767 YP_002414351.1 CDS gltB NC_011751.1 3807686 3812239 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3807686..3812239 Escherichia coli UMN026 7159136 YP_002414352.1 CDS gltD NC_011751.1 3812252 3813670 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3812252..3813670 Escherichia coli UMN026 7156574 YP_002414353.1 CDS yhcG NC_011751.1 3813854 3814981 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3813854..3814981 Escherichia coli UMN026 7156575 YP_002414354.1 CDS yhcH NC_011751.1 3815041 3815505 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3815041..3815505) Escherichia coli UMN026 7159137 YP_002414355.1 CDS nanK NC_011751.1 3815502 3816377 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3815502..3816377) Escherichia coli UMN026 7159138 YP_002414356.1 CDS nanE NC_011751.1 3816374 3817063 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3816374..3817063) Escherichia coli UMN026 7157236 YP_002414357.1 CDS nanT NC_011751.1 3817111 3818601 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96011396, 9864311, 7592358; Product type t : transporter; putative sialic acid transporter complement(3817111..3818601) Escherichia coli UMN026 7157234 YP_002414358.1 CDS nanA NC_011751.1 3818710 3819603 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3818710..3819603) Escherichia coli UMN026 7157239 YP_002414359.1 CDS nanR NC_011751.1 3819726 3820517 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3819726..3820517) Escherichia coli UMN026 7157233 YP_002414360.1 CDS dcuD NC_011751.1 3820897 3822264 D YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD 3820897..3822264 Escherichia coli UMN026 7157238 YP_002414361.1 CDS sspB NC_011751.1 3822308 3822805 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12445774, 94293773, 1721886, 3029697, 8022275; Product type f : factor; ClpXP protease specificity-enhancing factor complement(3822308..3822805) Escherichia coli UMN026 7156121 YP_002414362.1 CDS sspA NC_011751.1 3822811 3823449 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3822811..3823449) Escherichia coli UMN026 7157987 YP_002414363.1 CDS rpsI NC_011751.1 3823844 3824236 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3823844..3824236) Escherichia coli UMN026 7157986 YP_002414364.1 CDS rplM NC_011751.1 3824252 3824680 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3824252..3824680) Escherichia coli UMN026 7157775 YP_002414365.1 CDS yhcM NC_011751.1 3824899 3826026 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3824899..3826026) Escherichia coli UMN026 7157735 YP_002414366.1 CDS yhcB NC_011751.1 3826220 3826618 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type pe : putative enzyme; cytochrome d ubiquinol oxidase subunit III 3826220..3826618 Escherichia coli UMN026 7159139 YP_002414367.1 CDS degQ NC_011751.1 3826772 3828139 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8830688, 96165272, 8576051, 8576052, 9740056; Product type e : enzyme; serine endoprotease 3826772..3828139 Escherichia coli UMN026 7159135 YP_002414368.1 CDS degS NC_011751.1 3828229 3829296 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15137941, 15225661, 21352996, 96165272, 99431977, 3322223, 8576051; Product type e : enzyme; serine endoprotease 3828229..3829296 Escherichia coli UMN026 7156138 YP_002414369.1 CDS mdh NC_011751.1 3829359 3830297 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3829359..3830297) Escherichia coli UMN026 7156139 YP_002414370.1 CDS argR NC_011751.1 3830732 3831202 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3830732..3831202 Escherichia coli UMN026 7157069 YP_002414371.1 CDS yhcN NC_011751.1 3831567 3831830 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3831567..3831830 Escherichia coli UMN026 7155779 YP_002414372.1 CDS yhcO NC_011751.1 3831886 3832158 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative barnase inhibitor complement(3831886..3832158) Escherichia coli UMN026 7159140 YP_002414373.1 CDS aaeB NC_011751.1 3832250 3834217 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3832250..3834217) Escherichia coli UMN026 7159141 YP_002414374.1 CDS aaeA NC_011751.1 3834223 3835155 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3834223..3835155) Escherichia coli UMN026 7155657 YP_002414375.1 CDS aaeX NC_011751.1 3835163 3835366 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3835163..3835366) Escherichia coli UMN026 7155656 YP_002414376.1 CDS aaeR NC_011751.1 3835549 3836478 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489430; Product type r : regulator; putative DNA-binding transcriptional regulator 3835549..3836478 Escherichia coli UMN026 7155659 YP_002414377.1 CDS tldD NC_011751.1 3836606 3838051 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3836606..3838051) Escherichia coli UMN026 7155658 YP_002414378.1 CDS yhdP NC_011751.1 3838207 3842007 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10960106; Product type pm : putative membrane component; hypothetical protein complement(3838207..3842007) Escherichia coli UMN026 7158076 YP_002414379.1 CDS rng NC_011751.1 3842075 3843544 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3842075..3843544) Escherichia coli UMN026 7159147 YP_002414380.1 CDS yhdE NC_011751.1 3843534 3844127 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3843534..3844127) Escherichia coli UMN026 7157712 YP_002414381.1 CDS mreD NC_011751.1 3844136 3844624 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3844136..3844624) Escherichia coli UMN026 7159142 YP_002414382.1 CDS mreC NC_011751.1 3844624 3845640 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3844624..3845640) Escherichia coli UMN026 7157181 YP_002414383.1 CDS mreB NC_011751.1 3845706 3846749 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3845706..3846749) Escherichia coli UMN026 7157180 YP_002414384.1 CDS ECUMN_3725 NC_011751.1 3846857 3847045 D Evidence 6 : Doubtful CDS; hypothetical protein 3846857..3847045 Escherichia coli UMN026 7157179 YP_002414385.1 CDS csrD NC_011751.1 3847054 3848994 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3847054..3848994) Escherichia coli UMN026 7155364 YP_002414386.1 CDS yhdH NC_011751.1 3849146 3850120 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 3849146..3850120 Escherichia coli UMN026 7156046 YP_002414387.1 CDS ECUMN_3728 NC_011751.1 3850157 3850987 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3850157..3850987 Escherichia coli UMN026 7159143 YP_002414388.1 CDS accB NC_011751.1 3851853 3852323 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3851853..3852323 Escherichia coli UMN026 7155365 YP_002414389.1 CDS accC NC_011751.1 3852334 3853683 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3852334..3853683 Escherichia coli UMN026 7155672 YP_002414390.1 CDS yhdT NC_011751.1 3853792 3854034 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3853792..3854034 Escherichia coli UMN026 7155673 YP_002414391.1 CDS panF NC_011751.1 3854024 3855475 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3854024..3855475 Escherichia coli UMN026 7159148 YP_002414392.1 CDS prmA NC_011751.1 3855487 3856368 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3855487..3856368 Escherichia coli UMN026 7157381 YP_002414393.1 CDS dusB NC_011751.1 3856697 3857662 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566, 1459953, 1547773, 2835774, 2837762, 8226664; Product type e : enzyme; tRNA -dihydrouridine synthase B 3856697..3857662 Escherichia coli UMN026 7157527 YP_002414394.1 CDS fis NC_011751.1 3857688 3857984 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3857688..3857984 Escherichia coli UMN026 7156212 YP_002414395.1 CDS yhdJ NC_011751.1 3858070 3858954 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15028690, 9073062; Product type e : enzyme; putative methyltransferase 3858070..3858954 Escherichia coli UMN026 7156366 YP_002414396.1 CDS yhdU NC_011751.1 3859038 3859217 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3859038..3859217 Escherichia coli UMN026 7159144 YP_002414397.1 CDS envR NC_011751.1 3859220 3859882 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8203018, 11257026, 8407802, 1720861; Product type r : regulator; DNA-binding transcriptional regulator EnvR complement(3859220..3859882) Escherichia coli UMN026 7159149 YP_002414398.1 CDS acrE NC_011751.1 3860281 3861438 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012493, 1720861; Product type lp : lipoprotein; cytoplasmic membrane lipoprotein 3860281..3861438 Escherichia coli UMN026 7156255 YP_002414399.1 CDS acrF NC_011751.1 3861450 3864554 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94262163, 99449638, 1720861, 8407802; Product type t : transporter; multidrug efflux system protein 3861450..3864554 Escherichia coli UMN026 7155690 YP_002414400.1 CDS yhdV NC_011751.1 3864807 3865028 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3864807..3865028 Escherichia coli UMN026 7155691 YP_002414401.1 CDS ECUMN_3742 NC_011751.1 3865254 3865430 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3865254..3865430 Escherichia coli UMN026 7159150 YP_002414402.1 CDS aapJ NC_011751.1 3865567 3866484 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter periplasmic-binding protein 3865567..3866484 Escherichia coli UMN026 7155366 YP_002414403.1 CDS aapQ NC_011751.1 3866552 3867733 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3866552..3867733 Escherichia coli UMN026 7155660 YP_002414404.1 CDS aapM NC_011751.1 3867743 3868846 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3867743..3868846 Escherichia coli UMN026 7155663 YP_002414405.1 CDS aapP NC_011751.1 3868854 3869612 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8809753, 8898392; Product type t : transporter; amino-acid ABC transporter ATP-binding protein 3868854..3869612 Escherichia coli UMN026 7155661 YP_002414406.1 CDS yrdA NC_011751.1 3875168 3876049 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3875168..3876049 Escherichia coli UMN026 7154983 YP_002414407.1 CDS yrdB NC_011751.1 3876025 3876282 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3876025..3876282) Escherichia coli UMN026 7159653 YP_002414408.1 CDS aroE NC_011751.1 3876279 3877097 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3876279..3877097) Escherichia coli UMN026 7159654 YP_002414409.1 CDS yrdC NC_011751.1 3877102 3877674 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor complement(3877102..3877674) Escherichia coli UMN026 7155787 YP_002414410.1 CDS yrdD NC_011751.1 3877679 3878221 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA topoisomerase complement(3877679..3878221) Escherichia coli UMN026 7159655 YP_002414411.1 CDS smg NC_011751.1 3878250 3878723 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8432722; hypothetical protein complement(3878250..3878723) Escherichia coli UMN026 7159656 YP_002414412.1 CDS smf NC_011751.1 3878695 3879819 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8112305, 8432722; DNA protecting protein DprA complement(3878695..3879819) Escherichia coli UMN026 7157941 YP_002414413.1 CDS def NC_011751.1 3879949 3880458 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3879949..3880458 Escherichia coli UMN026 7157940 YP_002414414.1 CDS fmt NC_011751.1 3880473 3881420 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3880473..3881420 Escherichia coli UMN026 7156136 YP_002414415.1 CDS rsmB NC_011751.1 3881466 3882755 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3881466..3882755 Escherichia coli UMN026 7156419 YP_002414416.1 CDS trkA NC_011751.1 3882777 3884153 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 3882777..3884153 Escherichia coli UMN026 7157797 YP_002414417.1 CDS mscL NC_011751.1 3884283 3884693 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3884283..3884693 Escherichia coli UMN026 7158108 YP_002414418.1 CDS yhdL NC_011751.1 3884690 3884908 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3884690..3884908) Escherichia coli UMN026 7157185 YP_002414419.1 CDS zntR NC_011751.1 3884964 3885389 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3884964..3885389) Escherichia coli UMN026 7159145 YP_002414420.1 CDS yhdN NC_011751.1 3885400 3885768 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3885400..3885768) Escherichia coli UMN026 7159688 YP_002414421.1 CDS rplQ NC_011751.1 3885875 3886258 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3885875..3886258) Escherichia coli UMN026 7159146 YP_002414422.1 CDS rpoA NC_011751.1 3886299 3887288 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3886299..3887288) Escherichia coli UMN026 7157739 YP_002414423.1 CDS rpsD NC_011751.1 3887314 3887934 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3887314..3887934) Escherichia coli UMN026 7157757 YP_002414424.1 CDS rpsK NC_011751.1 3887968 3888357 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3887968..3888357) Escherichia coli UMN026 7157770 YP_002414425.1 CDS rpsM NC_011751.1 3888374 3888730 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3888374..3888730) Escherichia coli UMN026 7157777 YP_002414426.1 CDS secY NC_011751.1 3889025 3890356 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3889025..3890356) Escherichia coli UMN026 7157779 YP_002414427.1 CDS rplO NC_011751.1 3890364 3890798 R late assembly protein; 50S ribosomal protein L15 complement(3890364..3890798) Escherichia coli UMN026 7157892 YP_002414428.1 CDS rpmD NC_011751.1 3890802 3890981 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3890802..3890981) Escherichia coli UMN026 7157737 YP_002414429.1 CDS rpsE NC_011751.1 3890985 3891488 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3890985..3891488) Escherichia coli UMN026 7157751 YP_002414430.1 CDS rplR NC_011751.1 3891503 3891856 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3891503..3891856) Escherichia coli UMN026 7157771 YP_002414431.1 CDS rplF NC_011751.1 3891866 3892399 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3891866..3892399) Escherichia coli UMN026 7157740 YP_002414432.1 CDS rpsH NC_011751.1 3892412 3892804 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3892412..3892804) Escherichia coli UMN026 7157730 YP_002414433.1 CDS rpsN NC_011751.1 3892838 3893143 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3892838..3893143) Escherichia coli UMN026 7157774 YP_002414434.1 CDS rplE NC_011751.1 3893158 3893697 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3893158..3893697) Escherichia coli UMN026 7157780 YP_002414435.1 CDS rplX NC_011751.1 3893712 3894026 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3893712..3894026) Escherichia coli UMN026 7157729 YP_002414436.1 CDS rplN NC_011751.1 3894037 3894408 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3894037..3894408) Escherichia coli UMN026 7157746 YP_002414437.1 CDS rpsQ NC_011751.1 3894573 3894827 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3894573..3894827) Escherichia coli UMN026 7157736 YP_002414438.1 CDS rpmC NC_011751.1 3894827 3895018 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3894827..3895018) Escherichia coli UMN026 7157783 YP_002414439.1 CDS rplP NC_011751.1 3895018 3895428 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3895018..3895428) Escherichia coli UMN026 7157750 YP_002414440.1 CDS rpsC NC_011751.1 3895441 3896142 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3895441..3896142) Escherichia coli UMN026 7157738 YP_002414441.1 CDS rplV NC_011751.1 3896160 3896492 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3896160..3896492) Escherichia coli UMN026 7157769 YP_002414442.1 CDS rpsS NC_011751.1 3896507 3896785 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3896507..3896785) Escherichia coli UMN026 7157744 YP_002414443.1 CDS rplB NC_011751.1 3896802 3897623 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3896802..3897623) Escherichia coli UMN026 7157785 YP_002414444.1 CDS rplW NC_011751.1 3897641 3897943 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3897641..3897943) Escherichia coli UMN026 7157726 YP_002414445.1 CDS rplD NC_011751.1 3897940 3898545 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3897940..3898545) Escherichia coli UMN026 7157745 YP_002414446.1 CDS rplC NC_011751.1 3898556 3899185 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3898556..3899185) Escherichia coli UMN026 7157728 YP_002414447.1 CDS rpsJ NC_011751.1 3899218 3899529 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3899218..3899529) Escherichia coli UMN026 7157727 YP_002414448.1 CDS ECUMN_3795 NC_011751.1 3899658 3899819 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3899658..3899819) Escherichia coli UMN026 7157776 YP_002414449.1 CDS ECUMN_3796 NC_011751.1 3899908 3900375 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative bifunctional prepilin peptidase HopD 3899908..3900375 Escherichia coli UMN026 7155367 YP_002414450.1 CDS bfr NC_011751.1 3900372 3900848 R iron storage protein; bacterioferritin complement(3900372..3900848) Escherichia coli UMN026 7155368 YP_002414451.1 CDS bfd NC_011751.1 3900921 3901115 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8954950, 9889981, 2661540, 8639572; Product type c : carrier; bacterioferritin-associated ferredoxin complement(3900921..3901115) Escherichia coli UMN026 7155872 YP_002414452.1 CDS tufA NC_011751.1 3901298 3902482 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3901298..3902482) Escherichia coli UMN026 7155871 YP_002414453.1 CDS fusA NC_011751.1 3902553 3904667 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3902553..3904667) Escherichia coli UMN026 7158139 YP_002414454.1 CDS rpsG NC_011751.1 3904764 3905234 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3904764..3905234) Escherichia coli UMN026 7156480 YP_002414455.1 CDS rpsL NC_011751.1 3905331 3905705 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3905331..3905705) Escherichia coli UMN026 7157773 YP_002414456.1 CDS tusB NC_011751.1 3905831 3906118 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3905831..3906118) Escherichia coli UMN026 7157778 YP_002414457.1 CDS tusC NC_011751.1 3906126 3906485 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3906126..3906485) Escherichia coli UMN026 7158143 YP_002414458.1 CDS tusD NC_011751.1 3906485 3906871 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3906485..3906871) Escherichia coli UMN026 7158144 YP_002414459.1 CDS yheO NC_011751.1 3906871 3907593 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(3906871..3907593) Escherichia coli UMN026 7158145 YP_002414460.1 CDS fkpA NC_011751.1 3907760 3908572 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3907760..3908572) Escherichia coli UMN026 7159151 YP_002414461.1 CDS slyX NC_011751.1 3908793 3909011 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3908793..3909011 Escherichia coli UMN026 7156373 YP_002414462.1 CDS slyD NC_011751.1 3909060 3909650 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3909060..3909650) Escherichia coli UMN026 7157939 YP_002414463.1 CDS yheV NC_011751.1 3909745 3909945 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3909745..3909945) Escherichia coli UMN026 7157938 YP_002414464.1 CDS kefB NC_011751.1 3909955 3911760 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3909955..3911760) Escherichia coli UMN026 7159155 YP_002414465.1 CDS kefG NC_011751.1 3911760 3912314 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3911760..3912314) Escherichia coli UMN026 7156903 YP_002414466.1 CDS yheS NC_011751.1 3912442 3914355 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 3912442..3914355 Escherichia coli UMN026 7156906 YP_002414467.1 CDS yheT NC_011751.1 3914355 3915377 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9889164; Product type pe : putative enzyme; putative hydrolase 3914355..3915377 Escherichia coli UMN026 7159152 YP_002414468.1 CDS yheU NC_011751.1 3915371 3915589 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3915371..3915589 Escherichia coli UMN026 7159153 YP_002414469.1 CDS prkB NC_011751.1 3915643 3916512 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2559876; Product type e : enzyme; phosphoribulokinase 3915643..3916512 Escherichia coli UMN026 7159154 YP_002414470.1 CDS yhfA NC_011751.1 3916567 3916971 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3916567..3916971) Escherichia coli UMN026 7157525 YP_002414471.1 CDS ECUMN_3819 NC_011751.1 3917051 3917266 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3917051..3917266 Escherichia coli UMN026 7156018 YP_002414472.1 CDS crp NC_011751.1 3917273 3917905 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3917273..3917905 Escherichia coli UMN026 7155369 YP_002414473.1 CDS yhfK NC_011751.1 3917944 3920046 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3917944..3920046 Escherichia coli UMN026 7156017 YP_002414474.1 CDS argD NC_011751.1 3920113 3921333 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein complement(3920113..3921333) Escherichia coli UMN026 7159158 YP_002414475.1 CDS pabA NC_011751.1 3921419 3921982 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3921419..3921982) Escherichia coli UMN026 7155771 YP_002414476.1 CDS fic NC_011751.1 3922014 3922616 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92021789, 94095125, 2007139, 2403545, 2546924, 7549107; Product type cp : cell process; cell filamentation protein Fic complement(3922014..3922616) Escherichia coli UMN026 7157373 YP_002414477.1 CDS yhfG NC_011751.1 3922606 3922773 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3922606..3922773) Escherichia coli UMN026 7156352 YP_002414478.1 CDS ppiA NC_011751.1 3922878 3923450 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 2001362, 2007139, 2190212, 2403545, 2546924, 8130188, 8180197; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase A complement(3922878..3923450) Escherichia coli UMN026 7159157 YP_002414479.1 CDS tsgA NC_011751.1 3923721 3924902 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20509826; Product type pt : putative transporter; hypothetical protein 3923721..3924902 Escherichia coli UMN026 7157505 YP_002414480.1 CDS nirB NC_011751.1 3925164 3927707 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93062014, 2200672, 2445993, 2543955; Product type e : enzyme; nitrite reductase, large subunit, NAD(P) H-binding 3925164..3927707 Escherichia coli UMN026 7158133 YP_002414481.1 CDS nirD NC_011751.1 3927704 3928030 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3927704..3928030 Escherichia coli UMN026 7157282 YP_002414482.1 CDS nirC NC_011751.1 3928156 3928962 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3928156..3928962 Escherichia coli UMN026 7157284 YP_002414483.1 CDS cysG NC_011751.1 3928981 3930354 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3928981..3930354 Escherichia coli UMN026 7157283 YP_002414484.1 CDS yhfL NC_011751.1 3930606 3930773 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3930606..3930773 Escherichia coli UMN026 7156083 YP_002414485.1 CDS yhfS NC_011751.1 3930880 3931965 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3930880..3931965) Escherichia coli UMN026 7159159 YP_002414486.1 CDS yhfT NC_011751.1 3931977 3933281 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3931977..3933281) Escherichia coli UMN026 7159160 YP_002414487.1 CDS yhfU NC_011751.1 3933293 3933646 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3933293..3933646) Escherichia coli UMN026 7159161 YP_002414488.1 CDS php NC_011751.1 3933657 3934535 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase complement(3933657..3934535) Escherichia coli UMN026 7159162 YP_002414489.1 CDS yhfW NC_011751.1 3934532 3935758 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mutase complement(3934532..3935758) Escherichia coli UMN026 7157463 YP_002414490.1 CDS yhfX NC_011751.1 3935758 3936921 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amino acid racemase complement(3935758..3936921) Escherichia coli UMN026 7159163 YP_002414491.1 CDS yhfY NC_011751.1 3937005 3937367 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3937005..3937367) Escherichia coli UMN026 7159164 YP_002414492.1 CDS yhfZ NC_011751.1 3937384 3938289 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3937384..3938289) Escherichia coli UMN026 7159165 YP_002414493.1 CDS trpS NC_011751.1 3938449 3939453 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3938449..3939453) Escherichia coli UMN026 7159166 YP_002414494.1 CDS gph NC_011751.1 3939446 3940204 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3939446..3940204) Escherichia coli UMN026 7158124 YP_002414495.1 CDS rpe NC_011751.1 3940197 3940874 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3940197..3940874) Escherichia coli UMN026 7156603 YP_002414496.1 CDS dam NC_011751.1 3940892 3941728 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136529, 92262475, 92272672, 2549371, 6300769, 7603433, 8341592; Product type e : enzyme; DNA adenine methylase complement(3940892..3941728) Escherichia coli UMN026 7157722 YP_002414497.1 CDS damX NC_011751.1 3941835 3943121 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3941835..3943121) Escherichia coli UMN026 7156105 YP_002414498.1 CDS aroB NC_011751.1 3943213 3944301 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3943213..3944301) Escherichia coli UMN026 7156106 YP_002414499.1 CDS aroK NC_011751.1 3944358 3944879 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3944358..3944879) Escherichia coli UMN026 7155784 YP_002414500.1 CDS hofQ NC_011751.1 3945280 3946518 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3945280..3946518) Escherichia coli UMN026 7155791 YP_002414501.1 CDS yrfA NC_011751.1 3946430 3946834 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3946430..3946834) Escherichia coli UMN026 7156693 YP_002414502.1 CDS yrfB NC_011751.1 3946824 3947264 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(3946824..3947264) Escherichia coli UMN026 7159657 YP_002414503.1 CDS yrfC NC_011751.1 3947248 3947787 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial assembly protein (pilN-like) complement(3947248..3947787) Escherichia coli UMN026 7159658 YP_002414504.1 CDS yrfD NC_011751.1 3947787 3948566 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative pilus assembly protein complement(3947787..3948566) Escherichia coli UMN026 7159659 YP_002414505.1 CDS mrcA NC_011751.1 3948686 3951238 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3948686..3951238 Escherichia coli UMN026 7159660 YP_002414506.1 CDS nudE NC_011751.1 3951406 3951966 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3951406..3951966) Escherichia coli UMN026 7157175 YP_002414507.1 CDS igaA NC_011751.1 3952286 3954421 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11553591; Product type r : regulator; intracellular growth attenuator protein 3952286..3954421 Escherichia coli UMN026 7157319 YP_002414508.1 CDS yrfG NC_011751.1 3954486 3955154 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 3954486..3955154 Escherichia coli UMN026 7156793 YP_002414509.1 CDS hslR NC_011751.1 3955165 3955566 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9867837, 10675343, 10675344; Product type f : factor; ribosome-associated heat shock protein Hsp15 3955165..3955566 Escherichia coli UMN026 7159661 YP_002414510.1 CDS hslO NC_011751.1 3955591 3956469 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3955591..3956469 Escherichia coli UMN026 7156722 YP_002414511.1 CDS yhgE NC_011751.1 3956532 3958256 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20223645; Product type pm : putative membrane component; hypothetical protein complement(3956532..3958256) Escherichia coli UMN026 7156721 YP_002414512.1 CDS ECUMN_3861 NC_011751.1 3958332 3958463 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3958332..3958463) Escherichia coli UMN026 7159168 YP_002414513.1 CDS pck NC_011751.1 3958635 3960257 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3958635..3960257 Escherichia coli UMN026 7155370 YP_002414514.1 CDS envZ NC_011751.1 3960333 3961685 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3960333..3961685) Escherichia coli UMN026 7157396 YP_002414515.1 CDS ompR NC_011751.1 3961682 3962401 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3961682..3962401) Escherichia coli UMN026 7156257 YP_002414516.1 CDS greB NC_011751.1 3962629 3963105 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3962629..3963105 Escherichia coli UMN026 7157349 YP_002414517.1 CDS yhgF NC_011751.1 3963202 3965523 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8755871; Product type f : factor; transcriptional accessory protein 3963202..3965523 Escherichia coli UMN026 7156610 YP_002414518.1 CDS feoA NC_011751.1 3965980 3966207 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012482, 8407793; Product type t : transporter; ferrous iron transport protein A 3965980..3966207 Escherichia coli UMN026 7159169 YP_002414519.1 CDS feoB NC_011751.1 3966224 3968545 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3966224..3968545 Escherichia coli UMN026 7156331 YP_002414520.1 CDS yhgG NC_011751.1 3968545 3968781 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3968545..3968781 Escherichia coli UMN026 7156332 YP_002414521.1 CDS yhgA NC_011751.1 3968983 3969876 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2678009; Product type ph : phenotype; hypothetical protein 3968983..3969876 Escherichia coli UMN026 7159170 YP_002414522.1 CDS bioH NC_011751.1 3970096 3970866 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3970096..3970866) Escherichia coli UMN026 7159167 YP_002414523.1 CDS gntX NC_011751.1 3970904 3971587 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3970904..3971587 Escherichia coli UMN026 7155881 YP_002414524.1 CDS gntY NC_011751.1 3971646 3972221 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 3971646..3972221 Escherichia coli UMN026 7156600 YP_002414525.1 CDS gntT NC_011751.1 3972582 3973898 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 4574689, 4582156, 93139975, 97141270, 98019089, 2845225, 3040894, 7984428, 9045817; Product type t : transporter; gluconate transporter 3972582..3973898 Escherichia coli UMN026 7156601 YP_002414526.1 CDS malQ NC_011751.1 3973946 3976027 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3973946..3976027) Escherichia coli UMN026 7156598 YP_002414527.1 CDS malP NC_011751.1 3976037 3978430 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033892, 10220320, 10469642, 2845225, 3037809, 3155826, 6283313, 6339728, 6986282, 9009262; Product type e : enzyme; maltodextrin phosphorylase complement(3976037..3978430) Escherichia coli UMN026 7157048 YP_002414528.1 CDS malT NC_011751.1 3979053 3981758 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3979053..3981758 Escherichia coli UMN026 7157047 YP_002414529.1 CDS rtcA NC_011751.1 3981801 3982817 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3981801..3982817) Escherichia coli UMN026 7157050 YP_002414530.1 CDS rtcB NC_011751.1 3982821 3984047 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9738023; hypothetical protein complement(3982821..3984047) Escherichia coli UMN026 7157812 YP_002414531.1 CDS rtcR NC_011751.1 3984236 3985834 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9738023, 3045764, 7920643, 7984428; Product type r : regulator; sigma 54-dependent transcriptional regulator of rtcBA expression 3984236..3985834 Escherichia coli UMN026 7157813 YP_002414532.1 CDS glpR NC_011751.1 3985816 3986574 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3985816..3986574) Escherichia coli UMN026 7157814 YP_002414533.1 CDS glpG NC_011751.1 3986591 3987421 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3986591..3987421) Escherichia coli UMN026 7156570 YP_002414534.1 CDS glpE NC_011751.1 3987466 3987792 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3987466..3987792) Escherichia coli UMN026 7156567 YP_002414535.1 CDS glpD NC_011751.1 3987982 3989487 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3987982..3989487 Escherichia coli UMN026 7156565 YP_002414536.1 CDS ECUMN_3885 NC_011751.1 3989994 3991145 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial adhesin complement(3989994..3991145) Escherichia coli UMN026 7156564 YP_002414537.1 CDS ECUMN_3886 NC_011751.1 3991138 3991941 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative periplasmic pilin chaperone complement(3991138..3991941) Escherichia coli UMN026 7155371 YP_002414538.1 CDS ECUMN_3887 NC_011751.1 3991883 3992407 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative exported fimbrial-like adhesin protein complement(3991883..3992407) Escherichia coli UMN026 7155372 YP_002414539.1 CDS ECUMN_3888 NC_011751.1 3992415 3992987 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial minor structural subunit complement(3992415..3992987) Escherichia coli UMN026 7155373 YP_002414540.1 CDS aufC NC_011751.1 3992978 3995569 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor; putative outer membrane export usher protein AufC complement(3992978..3995569) Escherichia coli UMN026 7155374 YP_002414541.1 CDS ECUMN_3890 NC_011751.1 3995611 3996363 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative fimbria chaperone protein complement(3995611..3996363) Escherichia coli UMN026 7155843 YP_002414542.1 CDS aufA NC_011751.1 3996484 3997188 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15213132; Product type s : structure; Auf fimbriae major fimbrial subunit AufA complement(3996484..3997188) Escherichia coli UMN026 7155375 YP_002414543.1 CDS glgP NC_011751.1 3997672 4000119 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88330897, 91104907, 91236706, 2645169, 2975249, 3047129, 3097003; Product type e : enzyme; glycogen phosphorylase complement(3997672..4000119) Escherichia coli UMN026 7155842 YP_002414544.1 CDS glgA NC_011751.1 4000138 4001571 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(4000138..4001571) Escherichia coli UMN026 7156540 YP_002414545.1 CDS glgC NC_011751.1 4001571 4002866 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(4001571..4002866) Escherichia coli UMN026 7156537 YP_002414546.1 CDS glgX NC_011751.1 4002884 4004857 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme complement(4002884..4004857) Escherichia coli UMN026 7156539 YP_002414547.1 CDS glgB NC_011751.1 4004854 4007040 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme complement(4004854..4007040) Escherichia coli UMN026 7156542 YP_002414548.1 CDS asd NC_011751.1 4007313 4008416 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(4007313..4008416) Escherichia coli UMN026 7156538 YP_002414549.1 CDS yhgN NC_011751.1 4008608 4009201 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 4008608..4009201 Escherichia coli UMN026 7155809 YP_002414550.1 CDS gntU NC_011751.1 4009258 4010598 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655507, 9119199, 9135111, 97141270; Product type t : transporter; low affinity gluconate transporter complement(4009258..4010598) Escherichia coli UMN026 7159171 YP_002414551.1 CDS gntK NC_011751.1 4010602 4011129 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 complement(4010602..4011129) Escherichia coli UMN026 7156599 YP_002414552.1 CDS gntR NC_011751.1 4011268 4012263 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9135111, 93139975, 9537375, 8655507; Product type r : regulator; DNA-binding transcriptional repressor complement(4011268..4012263) Escherichia coli UMN026 7156595 YP_002414553.1 CDS yhhW NC_011751.1 4012487 4013182 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4012487..4013182) Escherichia coli UMN026 7156597 YP_002414554.1 CDS yhhX NC_011751.1 4013305 4014342 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10493123; Product type pe : putative enzyme; putative dehydrogenase complement(4013305..4014342) Escherichia coli UMN026 7159187 YP_002414555.1 CDS ECUMN_3904 NC_011751.1 4014376 4014561 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4014376..4014561) Escherichia coli UMN026 7159188 YP_002414556.1 CDS yhhY NC_011751.1 4014677 4015165 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase 4014677..4015165 Escherichia coli UMN026 7157855 YP_002414557.1 CDS yhhZ NC_011751.1 4015401 4016579 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4015401..4016579 Escherichia coli UMN026 7159189 YP_002414558.1 CDS yrhA NC_011751.1 4016576 4017070 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4016576..4017070 Escherichia coli UMN026 7159190 YP_002414559.1 CDS yrhB NC_011751.1 4017520 4017804 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4017520..4017804 Escherichia coli UMN026 7159662 YP_002414560.1 CDS ggt NC_011751.1 4017842 4019584 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(4017842..4019584) Escherichia coli UMN026 7159663 YP_002414561.1 CDS yhhA NC_011751.1 4019704 4020144 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4019704..4020144 Escherichia coli UMN026 7156527 YP_002414562.1 CDS ugpQ NC_011751.1 4020131 4020874 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase complement(4020131..4020874) Escherichia coli UMN026 7159172 YP_002414563.1 CDS ugpC NC_011751.1 4020871 4021941 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(4020871..4021941) Escherichia coli UMN026 7158169 YP_002414564.1 CDS ugpE NC_011751.1 4021943 4022788 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(4021943..4022788) Escherichia coli UMN026 7158167 YP_002414565.1 CDS ugpA NC_011751.1 4022785 4023672 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(4022785..4023672) Escherichia coli UMN026 7158168 YP_002414566.1 CDS ugpB NC_011751.1 4023770 4025086 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(4023770..4025086) Escherichia coli UMN026 7158165 YP_002414567.1 CDS livF NC_011751.1 4025484 4026197 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4025484..4026197) Escherichia coli UMN026 7158166 YP_002414568.1 CDS livG NC_011751.1 4026199 4026966 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4026199..4026966) Escherichia coli UMN026 7156984 YP_002414569.1 CDS livM NC_011751.1 4026963 4028240 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine permease complement(4026963..4028240) Escherichia coli UMN026 7156985 YP_002414570.1 CDS livH NC_011751.1 4028237 4029163 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid permease LivH complement(4028237..4029163) Escherichia coli UMN026 7156989 YP_002414571.1 CDS livK NC_011751.1 4029211 4030320 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649683, 3891753, 4077929, 9298646, 9298646; Product type t : transporter; leucine ABC transporter periplasmic-binding protein complement(4029211..4030320) Escherichia coli UMN026 7156986 YP_002414572.1 CDS yhhK NC_011751.1 4030744 4031127 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4030744..4031127 Escherichia coli UMN026 7156988 YP_002414573.1 CDS livJ NC_011751.1 4031327 4032430 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649682, 328304, 3891753, 4077929, 9298646, 10972807; Product type t : transporter; leucine/isoleucine/valine ABC transporter periplasmic-binding protein complement(4031327..4032430) Escherichia coli UMN026 7159181 YP_002414574.1 CDS rpoH NC_011751.1 4032702 4033556 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(4032702..4033556) Escherichia coli UMN026 7156987 YP_002414575.1 CDS ftsX NC_011751.1 4033801 4034859 R putative ABC transporter, membrane protein; cell division protein FtsX complement(4033801..4034859) Escherichia coli UMN026 7157762 YP_002414576.1 CDS ftsE NC_011751.1 4034852 4035520 R putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(4034852..4035520) Escherichia coli UMN026 7156466 YP_002414577.1 CDS ftsY NC_011751.1 4035523 4037019 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(4035523..4037019) Escherichia coli UMN026 7156458 YP_002414578.1 CDS rsmD NC_011751.1 4037169 4037765 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4037169..4037765 Escherichia coli UMN026 7156467 YP_002414579.1 CDS ECUMN_3928 NC_011751.1 4037632 4038024 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4037632..4038024 Escherichia coli UMN026 7159173 YP_002414580.1 CDS yhhM NC_011751.1 4038027 4038386 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4038027..4038386) Escherichia coli UMN026 7155377 YP_002414581.1 CDS yhhN NC_011751.1 4038527 4039153 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4038527..4039153 Escherichia coli UMN026 7159182 YP_002414582.1 CDS zntA NC_011751.1 4039227 4041425 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4039227..4041425 Escherichia coli UMN026 7159183 YP_002414583.1 CDS ECUMN_3932 NC_011751.1 4041458 4041766 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4041458..4041766) Escherichia coli UMN026 7159687 YP_002414584.1 CDS tusA NC_011751.1 4041981 4042226 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(4041981..4042226) Escherichia coli UMN026 7155378 YP_002414585.1 CDS yhhQ NC_011751.1 4042447 4043112 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4042447..4043112 Escherichia coli UMN026 7158142 YP_002414586.1 CDS dcrB NC_011751.1 4043185 4043742 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12558182, 8752353; Product type t : transporter; hypothetical protein 4043185..4043742 Escherichia coli UMN026 7159184 YP_002414587.1 CDS yhhS NC_011751.1 4043746 4044963 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; major facilitator superfamily transporter complement(4043746..4044963) Escherichia coli UMN026 7156116 YP_002414588.1 CDS yhhT NC_011751.1 4045095 4046144 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4045095..4046144 Escherichia coli UMN026 7159185 YP_002414589.1 CDS ECUMN_3938 NC_011751.1 4046524 4046913 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4046524..4046913 Escherichia coli UMN026 7159186 YP_002414590.1 CDS ECUMN_3939 NC_011751.1 4046973 4048040 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase 4046973..4048040 Escherichia coli UMN026 7155379 YP_002414591.1 CDS ECUMN_3940 NC_011751.1 4048057 4048803 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4048057..4048803 Escherichia coli UMN026 7155380 YP_002414592.1 CDS ECUMN_3941 NC_011751.1 4048782 4049621 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 1-acylglycerol-3-phosphate O-acyltransferase 4048782..4049621 Escherichia coli UMN026 7155381 YP_002414593.1 CDS ECUMN_3942 NC_011751.1 4049596 4049853 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative acyl carrier protein 4049596..4049853 Escherichia coli UMN026 7155382 YP_002414594.1 CDS ECUMN_3943 NC_011751.1 4049865 4050116 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 4049865..4050116 Escherichia coli UMN026 7155383 YP_002414595.1 CDS ECUMN_3944 NC_011751.1 4050121 4050702 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 4050121..4050702 Escherichia coli UMN026 7155384 YP_002414596.1 CDS ECUMN_3945 NC_011751.1 4050660 4052060 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative fatty acid degradation enzyme 4050660..4052060 Escherichia coli UMN026 7155385 YP_002414597.1 CDS ECUMN_3946 NC_011751.1 4052017 4052400 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative fatty acid degradation enzyme 4052017..4052400 Escherichia coli UMN026 7155386 YP_002414598.1 CDS ECUMN_3947 NC_011751.1 4052391 4054067 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 4052391..4054067 Escherichia coli UMN026 7155387 YP_002414599.1 CDS ECUMN_3948 NC_011751.1 4054071 4054493 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thioesterase 4054071..4054493 Escherichia coli UMN026 7155388 YP_002414600.1 CDS ECUMN_3949 NC_011751.1 4054490 4055095 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative outer membrane lipoprotein carrier protein 4054490..4055095 Escherichia coli UMN026 7155389 YP_002414601.1 CDS ECUMN_3950 NC_011751.1 4055064 4057382 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4055064..4057382 Escherichia coli UMN026 7155390 YP_002414602.1 CDS ECUMN_3951 NC_011751.1 4057379 4057963 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4057379..4057963 Escherichia coli UMN026 7155391 YP_002414603.1 CDS ECUMN_3952 NC_011751.1 4057956 4059134 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase I 4057956..4059134 Escherichia coli UMN026 7155392 YP_002414604.1 CDS ECUMN_3953 NC_011751.1 4059131 4059595 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 3-hydroxy-fatty acyl-(acyl carrier protein) dehydratase 4059131..4059595 Escherichia coli UMN026 7155393 YP_002414605.1 CDS fabG NC_011751.1 4059595 4060326 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 4059595..4060326 Escherichia coli UMN026 7155394 YP_002414606.1 CDS ECUMN_3955 NC_011751.1 4060323 4061552 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 4060323..4061552 Escherichia coli UMN026 7155395 YP_002414607.1 CDS acpT NC_011751.1 4061554 4062141 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20092861, 10625633, 8939709; Product type e : enzyme; holo-(acyl carrier protein) synthase 2 4061554..4062141 Escherichia coli UMN026 7155396 YP_002414608.1 CDS nikA NC_011751.1 4062252 4063826 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12960164, 7934931, 92077434, 7867647; Product type t : transporter; nickel ABC transporter periplasmic-binding protein 4062252..4063826 Escherichia coli UMN026 7155686 YP_002414609.1 CDS nikB NC_011751.1 4063826 4064770 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4063826..4064770 Escherichia coli UMN026 7157275 YP_002414610.1 CDS nikC NC_011751.1 4064767 4065600 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4064767..4065600 Escherichia coli UMN026 7157276 YP_002414611.1 CDS nikD NC_011751.1 4065600 4066364 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4065600..4066364 Escherichia coli UMN026 7157277 YP_002414612.1 CDS nikE NC_011751.1 4066361 4067167 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4066361..4067167 Escherichia coli UMN026 7157278 YP_002414613.1 CDS nikR NC_011751.1 4067172 4067573 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4067172..4067573 Escherichia coli UMN026 7157279 YP_002414614.1 CDS ECUMN_3963 NC_011751.1 4067763 4068518 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4067763..4068518 Escherichia coli UMN026 7157280 YP_002414615.1 CDS ECUMN_3964 NC_011751.1 4068531 4069016 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase system enzyme subunit IIA 4068531..4069016 Escherichia coli UMN026 7155397 YP_002414616.1 CDS ECUMN_3965 NC_011751.1 4069013 4069294 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase system enzyme IIB 4069013..4069294 Escherichia coli UMN026 7155398 YP_002414617.1 CDS ECUMN_3966 NC_011751.1 4069341 4070729 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative phosphotransferase system permease IIC 4069341..4070729 Escherichia coli UMN026 7155399 YP_002414618.1 CDS ECUMN_3967 NC_011751.1 4070722 4072230 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carbohydrate kinase 4070722..4072230 Escherichia coli UMN026 7155400 YP_002414619.1 CDS ECUMN_3968 NC_011751.1 4072220 4072489 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system 4072220..4072489 Escherichia coli UMN026 7155401 YP_002414620.1 CDS gatY NC_011751.1 4072520 4073371 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; putative fructose-1,6-bisphosphate aldolase 4072520..4073371 Escherichia coli UMN026 7155402 YP_002414621.1 CDS yhhJ NC_011751.1 4073462 4074586 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter membrane protein complement(4073462..4074586) Escherichia coli UMN026 7155403 YP_002414622.1 CDS rbbA NC_011751.1 4074586 4077321 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20074572; Product type e : enzyme; fused ribosome-associated ATPase/membrane protein complement(4074586..4077321) Escherichia coli UMN026 7159180 YP_002414623.1 CDS yhiI NC_011751.1 4077318 4078385 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative HlyD family secretion protein complement(4077318..4078385) Escherichia coli UMN026 7157619 YP_002414624.1 CDS yhiJ NC_011751.1 4078751 4080373 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4078751..4080373) Escherichia coli UMN026 7159193 YP_002414625.1 CDS ECUMN_3974 NC_011751.1 4080635 4082308 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4080635..4082308) Escherichia coli UMN026 7159194 YP_002414626.1 CDS ECUMN_3975 NC_011751.1 4082199 4082408 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4082199..4082408) Escherichia coli UMN026 7155404 YP_002414627.1 CDS yhiM NC_011751.1 4082607 4083659 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4082607..4083659 Escherichia coli UMN026 7155405 YP_002414628.1 CDS yhiN NC_011751.1 4083974 4085176 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(4083974..4085176) Escherichia coli UMN026 7159195 YP_002414629.1 CDS pitA NC_011751.1 4085408 4086907 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87014120; Product type t : transporter; phosphate transporter, low-affinity 4085408..4086907 Escherichia coli UMN026 7159196 YP_002414630.1 CDS yhiO NC_011751.1 4086978 4087313 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(4086978..4087313) Escherichia coli UMN026 7157468 YP_002414631.1 CDS uspA NC_011751.1 4087704 4088138 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 93086426, 93308072, 94203056, 10499297, 10652104, 10931298, 11157932, 1453957, 8506346, 8932299, 9298646, 9405142; Product type f : factor; universal stress global response regulator 4087704..4088138 Escherichia coli UMN026 7159197 YP_002414632.1 CDS yhiP NC_011751.1 4088454 4089923 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4088454..4089923 Escherichia coli UMN026 7158193 YP_002414633.1 CDS yhiQ NC_011751.1 4089972 4090724 R predicted SAM-dependent methyltransferase; putative methyltransferase complement(4089972..4090724) Escherichia coli UMN026 7159198 YP_002414634.1 CDS prlC NC_011751.1 4090732 4092774 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92394891, 1325967, 8366062; Product type e : enzyme; oligopeptidase A complement(4090732..4092774) Escherichia coli UMN026 7159199 YP_002414635.1 CDS yhiR NC_011751.1 4092977 4093819 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11591672; Product type pe : putative enzyme; putative DNA (exogenous) processing protein 4092977..4093819 Escherichia coli UMN026 7157526 YP_002414636.1 CDS gor NC_011751.1 4093891 4095243 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4093891..4095243 Escherichia coli UMN026 7159200 YP_002414637.1 CDS ECUMN_3987 NC_011751.1 4095402 4095581 D Evidence 6 : Doubtful CDS; hypothetical protein 4095402..4095581 Escherichia coli UMN026 7156602 YP_002414638.1 CDS arsR NC_011751.1 4096120 4096473 D regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 4096120..4096473 Escherichia coli UMN026 7155406 YP_002414639.1 CDS arsD NC_011751.1 4096521 4096883 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8674982; Product type r : regulator; Arsenical resistance operon trans-acting repressor 4096521..4096883 Escherichia coli UMN026 7155800 YP_002414640.1 CDS arsA NC_011751.1 4096877 4098652 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8674982; Product type e : enzyme; Arsenical pump-driving ATPase 4096877..4098652 Escherichia coli UMN026 7155799 YP_002414641.1 CDS arsB NC_011751.1 4098695 4099984 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter; arsenite/antimonite transporter 4098695..4099984 Escherichia coli UMN026 7155796 YP_002414642.1 CDS arsC NC_011751.1 4099997 4100422 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95355341, 7721697; Product type e : enzyme; arsenate reductase 4099997..4100422 Escherichia coli UMN026 7155797 YP_002414643.1 CDS ECUMN_3994 NC_011751.1 4100556 4100852 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4100556..4100852) Escherichia coli UMN026 7155798 YP_002414644.1 CDS ECUMN_3995 NC_011751.1 4100948 4101961 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 4100948..4101961 Escherichia coli UMN026 7155407 YP_002414645.1 CDS ECUMN_3996 NC_011751.1 4102542 4103765 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4102542..4103765 Escherichia coli UMN026 7155408 YP_002414646.1 CDS slp NC_011751.1 4104010 4104576 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293775, 8022277; Product type lp : lipoprotein; outer membrane lipoprotein 4104010..4104576 Escherichia coli UMN026 7155409 YP_002414647.1 CDS yhiF NC_011751.1 4104729 4105259 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8022277; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4104729..4105259 Escherichia coli UMN026 7157934 YP_002414648.1 CDS chuS NC_011751.1 4105320 4106348 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16275907; Product type e : enzyme; Heme oxygenase complement(4105320..4106348) Escherichia coli UMN026 7159192 YP_002414649.1 CDS chuA NC_011751.1 4106397 4108379 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11179376, 7768795, 9393841, 9680204, 9157252; Product type t : transporter; outer membrane hemin receptor complement(4106397..4108379) Escherichia coli UMN026 7155958 YP_002414650.1 CDS chuT NC_011751.1 4108985 4109977 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7768795, 9393841, 9680204; Product type pt : putative transporter; putative periplasmic binding protein 4108985..4109977 Escherichia coli UMN026 7155957 YP_002414651.1 CDS ECUMN_4003 NC_011751.1 4109997 4111334 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4109997..4111334 Escherichia coli UMN026 7155959 YP_002414652.1 CDS ECUMN_4004 NC_011751.1 4111347 4111841 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4111347..4111841 Escherichia coli UMN026 7155410 YP_002414653.1 CDS ECUMN_4005 NC_011751.1 4111841 4112464 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4111841..4112464 Escherichia coli UMN026 7155411 YP_002414654.1 CDS chuU NC_011751.1 4112513 4113505 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative hemin transport system permease 4112513..4113505 Escherichia coli UMN026 7155412 YP_002414655.1 CDS hmuV NC_011751.1 4113349 4114272 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4113349..4114272 Escherichia coli UMN026 7155960 YP_002414656.1 CDS yhiD NC_011751.1 4114324 4114971 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase complement(4114324..4114971) Escherichia coli UMN026 7155961 YP_002414657.1 CDS hdeB NC_011751.1 4115035 4115361 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8885264, 12071744, 8244952, 8455549, 9298646, 9868784; Product type pf : putative factor; acid-resistance protein complement(4115035..4115361) Escherichia coli UMN026 7159191 YP_002414658.1 CDS hdeA NC_011751.1 4115477 4115809 R inactive form; acid-resistance protein complement(4115477..4115809) Escherichia coli UMN026 7156645 YP_002414659.1 CDS hdeD NC_011751.1 4116064 4116636 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8244952, 8455549; Product type pm : putative membrane component; acid-resistance membrane protein 4116064..4116636 Escherichia coli UMN026 7156644 YP_002414660.1 CDS gadE NC_011751.1 4117433 4117960 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12399493, 12940989, 14702398; Product type r : regulator; DNA-binding transcriptional activator 4117433..4117960 Escherichia coli UMN026 7156646 YP_002414661.1 CDS mdtE NC_011751.1 4118299 4119456 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4118299..4119456 Escherichia coli UMN026 7156489 YP_002414662.1 CDS mdtF NC_011751.1 4119481 4122594 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug transporter, RpoS-dependent 4119481..4122594 Escherichia coli UMN026 7157081 YP_002414663.1 CDS gadW NC_011751.1 4122957 4123685 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12446650; Product type r : regulator; DNA-binding transcriptional activator complement(4122957..4123685) Escherichia coli UMN026 7157082 YP_002414664.1 CDS gadX NC_011751.1 4124054 4124878 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(4124054..4124878) Escherichia coli UMN026 7156492 YP_002414665.1 CDS gadA NC_011751.1 4125238 4126638 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92155241, 92394884, 99406302, 1522060, 1740158, 7764225, 9298646; Product type e : enzyme; glutamate decarboxylase A, PLP-dependent complement(4125238..4126638) Escherichia coli UMN026 7156491 YP_002414666.1 CDS yhjA NC_011751.1 4126849 4128246 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8163487, 14563563; Product type e : enzyme; cytochrome C peroxidase complement(4126849..4128246) Escherichia coli UMN026 7156486 YP_002414667.1 CDS treF NC_011751.1 4128651 4130300 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4128651..4130300 Escherichia coli UMN026 7159201 YP_002414668.1 CDS yhjB NC_011751.1 4130351 4130953 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding response regulator in two-component regulatory system complement(4130351..4130953) Escherichia coli UMN026 7158105 YP_002414669.1 CDS yhjC NC_011751.1 4131401 4132372 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4131401..4132372 Escherichia coli UMN026 7159202 YP_002414670.1 CDS yhjD NC_011751.1 4132421 4133434 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4132421..4133434 Escherichia coli UMN026 7159203 YP_002414671.1 CDS yhjE NC_011751.1 4133826 4135148 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4133826..4135148 Escherichia coli UMN026 7159204 YP_002414672.1 CDS yhjG NC_011751.1 4135330 4137405 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane biogenesis protein complement(4135330..4137405) Escherichia coli UMN026 7159205 YP_002414673.1 CDS yhjH NC_011751.1 4137460 4138227 R in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein complement(4137460..4138227) Escherichia coli UMN026 7159206 YP_002414674.1 CDS ECUMN_4027 NC_011751.1 4138196 4138375 D Evidence 6 : Doubtful CDS; hypothetical protein 4138196..4138375 Escherichia coli UMN026 7159207 YP_002414675.1 CDS kdgK NC_011751.1 4138459 4139388 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4359651, 13813474; Product type e : enzyme; ketodeoxygluconokinase 4138459..4139388 Escherichia coli UMN026 7155413 YP_002414676.1 CDS ECUMN_4029 NC_011751.1 4139360 4139944 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4139360..4139944) Escherichia coli UMN026 7156887 YP_002414677.1 CDS ECUMN_4030 NC_011751.1 4140006 4140326 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4140006..4140326) Escherichia coli UMN026 7155414 YP_002414678.1 CDS ECUMN_4031 NC_011751.1 4140330 4140809 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4140330..4140809) Escherichia coli UMN026 7155415 YP_002414679.1 CDS ECUMN_4033 NC_011751.1 4141163 4141612 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4141163..4141612) Escherichia coli UMN026 7155416 YP_002414680.1 CDS yhjJ NC_011751.1 4141792 4143288 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pe : putative enzyme; putative zinc-dependent peptidase complement(4141792..4143288) Escherichia coli UMN026 7155417 YP_002414681.1 CDS dctA NC_011751.1 4143508 4144794 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(4143508..4144794) Escherichia coli UMN026 7159208 YP_002414682.1 CDS yhjK NC_011751.1 4144977 4146926 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase complement(4144977..4146926) Escherichia coli UMN026 7156117 YP_002414683.1 CDS bcsZ NC_011751.1 4150502 4151608 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(4150502..4151608) Escherichia coli UMN026 7155861 YP_002414684.1 CDS bcsB NC_011751.1 4151615 4153954 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(4151615..4153954) Escherichia coli UMN026 7155865 YP_002414685.1 CDS ECUMN_4043 NC_011751.1 4156579 4157331 R cell division protein complement(4156579..4157331) Escherichia coli UMN026 7155858 YP_002414686.1 CDS yhjR NC_011751.1 4157343 4157531 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4157343..4157531) Escherichia coli UMN026 7155418 YP_002414687.1 CDS bcsE NC_011751.1 4157803 4159374 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme; putative cellulose biosynthesis protease 4157803..4159374 Escherichia coli UMN026 7159210 YP_002414688.1 CDS bcsF NC_011751.1 4159371 4159562 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4159371..4159562 Escherichia coli UMN026 7155862 YP_002414689.1 CDS bcsG NC_011751.1 4159559 4161238 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme; putative cellulose biosynthesis endoglucanase 4159559..4161238 Escherichia coli UMN026 7155863 YP_002414690.1 CDS ECUMN_4048 NC_011751.1 4162080 4162241 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4162080..4162241) Escherichia coli UMN026 7157636 YP_002414691.1 CDS yhjV NC_011751.1 4162391 4163662 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type t : transporter; transporter 4162391..4163662 Escherichia coli UMN026 7155419 YP_002414692.1 CDS dppF NC_011751.1 4163692 4164696 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(4163692..4164696) Escherichia coli UMN026 7159211 YP_002414693.1 CDS dppD NC_011751.1 4164693 4165676 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(4164693..4165676) Escherichia coli UMN026 7156199 YP_002414694.1 CDS dppC NC_011751.1 4165687 4166589 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7536291; Product type t : transporter; dipeptide transporter complement(4165687..4166589) Escherichia coli UMN026 7156198 YP_002414695.1 CDS dppB NC_011751.1 4166599 4167618 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(4166599..4167618) Escherichia coli UMN026 7156197 YP_002414696.1 CDS ECUMN_4054 NC_011751.1 4167636 4167779 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4167636..4167779 Escherichia coli UMN026 7156196 YP_002414697.1 CDS dppA NC_011751.1 4167769 4169376 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100289, 92065799, 1702779, 1956284, 7536291, 8527431, 8563629, 9298646, 9600841, 9740056, 10972807; Product type t : transporter; dipeptide ABC transporter periplasmic-binding protein complement(4167769..4169376) Escherichia coli UMN026 7155420 YP_002414698.1 CDS ECUMN_4056 NC_011751.1 4170045 4170767 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group complement(4170045..4170767) Escherichia coli UMN026 7156195 YP_002414699.1 CDS ECUMN_4057 NC_011751.1 4170872 4171402 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 complement(4170872..4171402) Escherichia coli UMN026 7155421 YP_002414700.1 CDS eptB NC_011751.1 4171725 4173416 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(4171725..4173416) Escherichia coli UMN026 7155616 YP_002414701.1 CDS yhjX NC_011751.1 4173740 4174948 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(4173740..4174948) Escherichia coli UMN026 7156266 YP_002414702.1 CDS yhjY NC_011751.1 4175177 4175875 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4175177..4175875) Escherichia coli UMN026 7159212 YP_002414703.1 CDS tag NC_011751.1 4176033 4176596 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 4176033..4176596 Escherichia coli UMN026 7159213 YP_002414704.1 CDS yiaC NC_011751.1 4176593 4177033 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11237876; Product type pe : putative enzyme; hypothetical protein 4176593..4177033 Escherichia coli UMN026 7158018 YP_002414705.1 CDS bisC NC_011751.1 4177002 4179281 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82119950, 90202748, 2180922, 374979; Product type e : enzyme; biotin sulfoxide reductase complement(4177002..4179281) Escherichia coli UMN026 7159216 YP_002414706.1 CDS yiaD NC_011751.1 4179488 4180147 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane lipoprotein 4179488..4180147 Escherichia coli UMN026 7155884 YP_002414707.1 CDS tiaE NC_011751.1 4180251 4181225 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15801772, 11237876, 99030322, 99357626, 9298646, 9811658; Product type e : enzyme; 2-oxo-carboxylic acid reductase 4180251..4181225 Escherichia coli UMN026 7159217 YP_002414708.1 CDS yiaF NC_011751.1 4181275 4181985 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4181275..4181985) Escherichia coli UMN026 7158070 YP_002414709.1 CDS yiaG NC_011751.1 4182419 4182709 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4182419..4182709 Escherichia coli UMN026 7159218 YP_002414710.1 CDS cspA NC_011751.1 4182990 4183202 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 90115858, 94293754, 94293756, 99177178, 10696873, 1597410, 1961761, 2404279, 7515185, 8197194, 9405743, 9439003, 9692981; Product type f : factor; major cold shock protein 4182990..4183202 Escherichia coli UMN026 7159219 YP_002414711.1 CDS glyS NC_011751.1 4183864 4185933 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(4183864..4185933) Escherichia coli UMN026 7156034 YP_002414712.1 CDS glyQ NC_011751.1 4185943 4186854 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(4185943..4186854) Escherichia coli UMN026 7156587 YP_002414713.1 CDS ysaB NC_011751.1 4186949 4187257 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4186949..4187257) Escherichia coli UMN026 7156586 YP_002414714.1 CDS yiaH NC_011751.1 4187432 4188427 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4187432..4188427 Escherichia coli UMN026 7159664 YP_002414715.1 CDS yiaA NC_011751.1 4188469 4188906 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4188469..4188906) Escherichia coli UMN026 7159220 YP_002414716.1 CDS yiaB NC_011751.1 4188951 4189292 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6320721; Product type pm : putative membrane component; hypothetical protein complement(4188951..4189292) Escherichia coli UMN026 7159214 YP_002414717.1 CDS xylB NC_011751.1 4189461 4190915 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 92366447, 95050816, 6320721; Product type e : enzyme; xylulokinase complement(4189461..4190915) Escherichia coli UMN026 7159215 YP_002414718.1 CDS xylA NC_011751.1 4190987 4192309 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(4190987..4192309) Escherichia coli UMN026 7158253 YP_002414719.1 CDS xylF NC_011751.1 4192675 4193667 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4192675..4193667 Escherichia coli UMN026 7158252 YP_002414720.1 CDS xylG NC_011751.1 4193745 4195286 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4193745..4195286 Escherichia coli UMN026 7158254 YP_002414721.1 CDS xylH NC_011751.1 4195264 4196445 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500; Product type t : transporter; D-xylose ABC transporter membrane protein 4195264..4196445 Escherichia coli UMN026 7158255 YP_002414722.1 CDS ECUMN_4080 NC_011751.1 4196357 4196533 D Evidence 6 : Doubtful CDS; hypothetical protein 4196357..4196533 Escherichia coli UMN026 7158256 YP_002414723.1 CDS xylR NC_011751.1 4196523 4197701 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 94316500; Product type r : regulator; DNA-binding transcriptional activator, xylose-binding 4196523..4197701 Escherichia coli UMN026 7155423 YP_002414724.1 CDS bax NC_011751.1 4197809 4198633 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1544897; hypothetical protein complement(4197809..4198633) Escherichia coli UMN026 7158257 YP_002414725.1 CDS malS NC_011751.1 4198953 4200983 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4198953..4200983 Escherichia coli UMN026 7155854 YP_002414726.1 CDS avtA NC_011751.1 4201161 4202414 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4201161..4202414 Escherichia coli UMN026 7157049 YP_002414727.1 CDS yiaI NC_011751.1 4202453 4202926 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative hydrogenase, 4Fe-4S ferredoxin-type component complement(4202453..4202926) Escherichia coli UMN026 7155844 YP_002414728.1 CDS yiaJ NC_011751.1 4203028 4203876 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20372646, 9826648; Product type r : regulator; DNA-binding transcriptional repressor complement(4203028..4203876) Escherichia coli UMN026 7159221 YP_002414729.1 CDS yiaK NC_011751.1 4204078 4205076 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4204078..4205076 Escherichia coli UMN026 7159222 YP_002414730.1 CDS yiaL NC_011751.1 4205087 4205554 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21617392; hypothetical protein 4205087..4205554 Escherichia coli UMN026 7159223 YP_002414731.1 CDS yiaM NC_011751.1 4205672 4206145 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM 4205672..4206145 Escherichia coli UMN026 7159224 YP_002414732.1 CDS yiaN NC_011751.1 4206148 4207425 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 4206148..4207425 Escherichia coli UMN026 7159225 YP_002414733.1 CDS yiaO NC_011751.1 4207438 4208424 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 4207438..4208424 Escherichia coli UMN026 7159226 YP_002414734.1 CDS lyxK NC_011751.1 4208428 4209924 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21617392, 95050816, 7961955; Product type e : enzyme; L-xylulose kinase 4208428..4209924 Escherichia coli UMN026 7159227 YP_002414735.1 CDS sgbH NC_011751.1 4209921 4210583 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4209921..4210583 Escherichia coli UMN026 7157035 YP_002414736.1 CDS sgbU NC_011751.1 4210576 4211436 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 4210576..4211436 Escherichia coli UMN026 7157912 YP_002414737.1 CDS sgbE NC_011751.1 4211430 4212125 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4211430..4212125 Escherichia coli UMN026 7157913 YP_002414738.1 CDS ECUMN_4097 NC_011751.1 4212157 4212972 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator protein complement(4212157..4212972) Escherichia coli UMN026 7157911 YP_002414739.1 CDS ECUMN_4098 NC_011751.1 4213198 4214598 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative major facilitator superfamily permease 4213198..4214598 Escherichia coli UMN026 7155424 YP_002414740.1 CDS ECUMN_4099 NC_011751.1 4214609 4216573 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4214609..4216573 Escherichia coli UMN026 7155425 YP_002414741.1 CDS ECUMN_4100 NC_011751.1 4216645 4217055 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4216645..4217055) Escherichia coli UMN026 7155426 YP_002414742.1 CDS ECUMN_4101 NC_011751.1 4217072 4217257 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4217072..4217257) Escherichia coli UMN026 7155427 YP_002414743.1 CDS ECUMN_4102 NC_011751.1 4217232 4217405 D Evidence 6 : Doubtful CDS; hypothetical protein 4217232..4217405 Escherichia coli UMN026 7155428 YP_002414744.1 CDS aldB NC_011751.1 4217535 4219073 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95286498, 7768815; Product type e : enzyme; aldehyde dehydrogenase B complement(4217535..4219073) Escherichia coli UMN026 7155429 YP_002414745.1 CDS yiaY NC_011751.1 4219274 4220425 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2935393; Product type e : enzyme; putative alcohol dehydrogenase complement(4219274..4220425) Escherichia coli UMN026 7155723 YP_002414746.1 CDS selB NC_011751.1 4220615 4222459 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264431, 91317715, 9315303, 94148228, 2140572, 2531290; Product type f : factor; selenocysteinyl-tRNA -specific translation factor complement(4220615..4222459) Escherichia coli UMN026 7159228 YP_002414747.1 CDS selA NC_011751.1 4222456 4223847 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4222456..4223847) Escherichia coli UMN026 7157894 YP_002414748.1 CDS yibF NC_011751.1 4223945 4224553 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8387990; Product type pe : putative enzyme; putative glutathione S-transferase complement(4223945..4224553) Escherichia coli UMN026 7157893 YP_002414749.1 CDS yibH NC_011751.1 4224624 4225760 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4224624..4225760) Escherichia coli UMN026 7159230 YP_002414750.1 CDS yibI NC_011751.1 4225763 4226125 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4225763..4226125) Escherichia coli UMN026 7159231 YP_002414751.1 CDS mtlA NC_011751.1 4226662 4228575 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052139, 92283796, 94131964, 1946374, 3135464, 3142516, 6309813, 9551558; Product type t : transporter; PTS system mannitol-specific transporter subunit IIABC 4226662..4228575 Escherichia coli UMN026 7159232 YP_002414752.1 CDS mtlD NC_011751.1 4228804 4229952 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90254197, 1964486, 3135464, 6384188, 8300537, 13295236; Product type e : enzyme; mannitol-1-phosphate 5-dehydrogenase 4228804..4229952 Escherichia coli UMN026 7157191 YP_002414753.1 CDS mtlR NC_011751.1 4229952 4230539 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4229952..4230539 Escherichia coli UMN026 7157192 YP_002414754.1 CDS yibT NC_011751.1 4230551 4230760 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4230551..4230760) Escherichia coli UMN026 7157193 YP_002414755.1 CDS yibL NC_011751.1 4231044 4231406 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4231044..4231406 Escherichia coli UMN026 7159237 YP_002414756.1 CDS ECUMN_4115 NC_011751.1 4231967 4232650 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4231967..4232650 Escherichia coli UMN026 7159234 YP_002414757.1 CDS lldP NC_011751.1 4238337 4239992 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012541, 11283302, 11785976, 8407843; Product type t : transporter; L-lactate permease 4238337..4239992 Escherichia coli UMN026 7155432 YP_002414758.1 CDS lldR NC_011751.1 4239992 4240768 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4239992..4240768 Escherichia coli UMN026 7156991 YP_002414759.1 CDS lldD NC_011751.1 4240765 4241955 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4240765..4241955 Escherichia coli UMN026 7156992 YP_002414760.1 CDS yibK NC_011751.1 4242028 4242501 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA /rRNA methyltransferase YibK 4242028..4242501 Escherichia coli UMN026 7156990 YP_002414761.1 CDS ECUMN_4122 NC_011751.1 4242558 4243280 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group complement(4242558..4243280) Escherichia coli UMN026 7159233 YP_002414762.1 CDS ECUMN_4123 NC_011751.1 4243385 4243915 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 complement(4243385..4243915) Escherichia coli UMN026 7155433 YP_002414763.1 CDS cysE NC_011751.1 4243989 4244810 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4243989..4244810) Escherichia coli UMN026 7155434 YP_002414764.1 CDS gpsA NC_011751.1 4244890 4245909 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4244890..4245909) Escherichia coli UMN026 7156082 YP_002414765.1 CDS secB NC_011751.1 4245909 4246376 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4245909..4246376) Escherichia coli UMN026 7156607 YP_002414766.1 CDS grxC NC_011751.1 4246439 4246690 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500, 95024051, 99175138, 11031118, 7937896, 8636094, 9973569; Product type c : carrier; glutaredoxin 3 complement(4246439..4246690) Escherichia coli UMN026 7157886 YP_002414767.1 CDS yibN NC_011751.1 4246833 4247264 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative rhodanese-related sulfurtransferase complement(4246833..4247264) Escherichia coli UMN026 7156616 YP_002414768.1 CDS gpmI NC_011751.1 4247509 4249053 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4247509..4249053 Escherichia coli UMN026 7159235 YP_002414769.1 CDS envC NC_011751.1 4249087 4250346 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12113939, 21972773; Product type cp : cell process; hypothetical protein 4249087..4250346 Escherichia coli UMN026 7156605 YP_002414770.1 CDS yibQ NC_011751.1 4250350 4251309 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative polysaccharide deacetylase 4250350..4251309 Escherichia coli UMN026 7156254 YP_002414771.1 CDS yibD NC_011751.1 4251296 4252330 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659689, 2647748; Product type pe : putative enzyme; putative glycosyl transferase complement(4251296..4252330) Escherichia coli UMN026 7159236 YP_002414772.1 CDS tdh NC_011751.1 4252569 4253594 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4252569..4253594) Escherichia coli UMN026 7159229 YP_002414773.1 CDS kbl NC_011751.1 4253604 4254800 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(4253604..4254800) Escherichia coli UMN026 7158043 YP_002414774.1 CDS htrL NC_011751.1 4255076 4255933 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4255076..4255933) Escherichia coli UMN026 7156885 YP_002414775.1 CDS rfaD NC_011751.1 4256237 4257169 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-mannoheptose-6-epimerase 4256237..4257169 Escherichia coli UMN026 7156731 YP_002414776.1 CDS waaF NC_011751.1 4257179 4258225 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4257179..4258225 Escherichia coli UMN026 7158216 YP_002414777.1 CDS waaC NC_011751.1 4258229 4259221 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20507564, 92250420, 93239678, 9446588, 1624462, 8478319; Product type e : enzyme; ADP-heptose:LPS heptosyl transferase I 4258229..4259221 Escherichia coli UMN026 7158217 YP_002414778.1 CDS rfaL NC_011751.1 4259218 4260426 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; O-antigen ligase 4259218..4260426 Escherichia coli UMN026 7158215 YP_002414779.1 CDS rfaK NC_011751.1 4260464 4261606 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Lipopolysaccharide 1, 2-N-acetylglucosaminetransferase complement(4260464..4261606) Escherichia coli UMN026 7157658 YP_002414780.1 CDS rfaJ NC_011751.1 4261615 4262628 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 99251135, 1624461; Product type e : enzyme; Lipopolysaccharide 1,2-glucosyltransferase complement(4261615..4262628) Escherichia coli UMN026 7157657 YP_002414781.1 CDS rfaY NC_011751.1 4262653 4263360 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1624462, 8041620, 9278503, 92250420, 92325067, 9756860; Product type e : enzyme; lipopolysaccharide core biosynthesis protein complement(4262653..4263360) Escherichia coli UMN026 7157656 YP_002414782.1 CDS rfaI NC_011751.1 4263386 4264393 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 9765561, 1624461; Product type e : enzyme; Lipopolysaccharide 1,3-galactosyltransferase complement(4263386..4264393) Escherichia coli UMN026 7157659 YP_002414783.1 CDS waaP NC_011751.1 4264436 4265242 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101922, 92121133, 92210496, 9756860, 1732225; Product type e : enzyme; kinase that phosphorylates core heptose of lipopolysaccharide complement(4264436..4265242) Escherichia coli UMN026 7157655 YP_002414784.1 CDS waaG NC_011751.1 4265226 4266350 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92210496, 92250420, 1447141, 1732225, 7988890; Product type e : enzyme; glucosyltransferase I complement(4265226..4266350) Escherichia coli UMN026 7158219 YP_002414785.1 CDS waaQ NC_011751.1 4266347 4267405 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9756860, 1447141, 1732225; Product type e : enzyme; lipopolysaccharide core biosynthesis protein complement(4266347..4267405) Escherichia coli UMN026 7158218 YP_002414786.1 CDS kdtA NC_011751.1 4267818 4269095 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4267818..4269095 Escherichia coli UMN026 7158220 YP_002414787.1 CDS coaD NC_011751.1 4269103 4269582 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4269103..4269582 Escherichia coli UMN026 7156899 YP_002414788.1 CDS mutM NC_011751.1 4269621 4270430 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4269621..4270430) Escherichia coli UMN026 7155989 YP_002414789.1 CDS rpmG NC_011751.1 4270528 4270695 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4270528..4270695) Escherichia coli UMN026 7157213 YP_002414790.1 CDS rpmB NC_011751.1 4270716 4270952 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4270716..4270952) Escherichia coli UMN026 7157754 YP_002414791.1 CDS radC NC_011751.1 4271169 4271837 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4271169..4271837) Escherichia coli UMN026 7157749 YP_002414792.1 CDS dfp NC_011751.1 4272009 4273229 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4272009..4273229 Escherichia coli UMN026 7159249 YP_002414793.1 CDS dut NC_011751.1 4273210 4273665 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4273210..4273665 Escherichia coli UMN026 7156147 YP_002414794.1 CDS slmA NC_011751.1 4273772 4274368 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4273772..4274368 Escherichia coli UMN026 7156214 YP_002414795.1 CDS pyrE NC_011751.1 4274405 4275046 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4274405..4275046) Escherichia coli UMN026 7158138 YP_002414796.1 CDS rph NC_011751.1 4275112 4275852 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4275112..4275852) Escherichia coli UMN026 7157600 YP_002414797.1 CDS yicC NC_011751.1 4275955 4276818 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4275955..4276818 Escherichia coli UMN026 7157723 YP_002414798.1 CDS dinD NC_011751.1 4277040 4277864 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 913680, 94334998, 95095962, 1925027, 2158980, 2664418, 8002613, 8057377, 8195095; Product type cp : cell process; DNA-damage-inducible protein D 4277040..4277864 Escherichia coli UMN026 7159238 YP_002414799.1 CDS yicG NC_011751.1 4278155 4278772 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4278155..4278772 Escherichia coli UMN026 7156167 YP_002414800.1 CDS ligB NC_011751.1 4278769 4280451 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4278769..4280451) Escherichia coli UMN026 7159240 YP_002414801.1 CDS gmk NC_011751.1 4280709 4281332 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4280709..4281332 Escherichia coli UMN026 7156980 YP_002414802.1 CDS rpoZ NC_011751.1 4281387 4281662 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4281387..4281662 Escherichia coli UMN026 7156590 YP_002414803.1 CDS spoT NC_011751.1 4281681 4283789 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12224635, 89255395, 93266525, 94068533, 2005134, 2549050; Product type e : enzyme; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4281681..4283789 Escherichia coli UMN026 7157765 YP_002414804.1 CDS trmH NC_011751.1 4283796 4284485 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4283796..4284485 Escherichia coli UMN026 7157964 YP_002414805.1 CDS recG NC_011751.1 4284491 4286572 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4284491..4286572 Escherichia coli UMN026 7158115 YP_002414806.1 CDS gltS NC_011751.1 4286606 4287811 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91203811, 93106943, 1544582, 2017136, 2254324; Product type t : transporter; glutamate transporter complement(4286606..4287811) Escherichia coli UMN026 7157642 YP_002414807.1 CDS yicE NC_011751.1 4288090 4289481 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4288090..4289481 Escherichia coli UMN026 7156581 YP_002414808.1 CDS yicH NC_011751.1 4289602 4291311 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4289602..4291311 Escherichia coli UMN026 7159239 YP_002414809.1 CDS insG NC_011751.1 4292627 4293955 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative IS4 transposase; KpLE2 phage-like element 4292627..4293955 Escherichia coli UMN026 7159242 YP_002414810.1 CDS yicJ NC_011751.1 4295130 4296512 R may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter complement(4295130..4296512) Escherichia coli UMN026 7159243 YP_002414811.1 CDS setC NC_011751.1 4297537 4298721 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10438463, 10209755; Product type pt : putative transporter; putative sugar efflux system 4297537..4298721 Escherichia coli UMN026 7155590 YP_002414812.1 CDS yicL NC_011751.1 4298832 4299755 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4298832..4299755 Escherichia coli UMN026 7157902 YP_002414813.1 CDS nlpA NC_011751.1 4299759 4300577 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88298691, 89359178, 9914480, 3003106; Product type lp : lipoprotein; cytoplasmic membrane lipoprotein-28 complement(4299759..4300577) Escherichia coli UMN026 7159245 YP_002414814.1 CDS yicS NC_011751.1 4300718 4301080 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4300718..4301080 Escherichia coli UMN026 7157285 YP_002414815.1 CDS ECUMN_4181 NC_011751.1 4301382 4301879 D Evidence 4 : Homologs of previously reported genes of unknown function; putative type III secretion chaperone 4301382..4301879 Escherichia coli UMN026 7159250 YP_002414816.1 CDS ECUMN_4182 NC_011751.1 4302126 4303907 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4302126..4303907 Escherichia coli UMN026 7155435 YP_002414817.1 CDS ECUMN_4183 NC_011751.1 4303920 4305071 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4303920..4305071 Escherichia coli UMN026 7155436 YP_002414818.1 CDS ECUMN_4184 NC_011751.1 4305115 4306464 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4305115..4306464 Escherichia coli UMN026 7155437 YP_002414819.1 CDS ECUMN_4185 NC_011751.1 4306667 4308364 D Activates the expression of invasion genes and activates the expression of prgHIJK which is part of the pathogenicity island 1 type III secretion system; invasion protein regulator 4306667..4308364 Escherichia coli UMN026 7155438 YP_002414820.1 CDS ECUMN_4186 NC_011751.1 4308416 4318672 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4308416..4318672) Escherichia coli UMN026 7155439 YP_002414821.1 CDS nepI NC_011751.1 4318874 4320232 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4318874..4320232) Escherichia coli UMN026 7155440 YP_002414822.1 CDS ECUMN_4188 NC_011751.1 4320285 4320644 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4320285..4320644 Escherichia coli UMN026 7159246 YP_002414823.1 CDS ECUMN_4189 NC_011751.1 4320628 4320951 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptional regulator 4320628..4320951 Escherichia coli UMN026 7155441 YP_002414824.1 CDS yicN NC_011751.1 4321067 4321519 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4321067..4321519) Escherichia coli UMN026 7155442 YP_002414825.1 CDS yicO NC_011751.1 4321572 4322906 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative xanthine/uracil permease complement(4321572..4322906) Escherichia coli UMN026 7159247 YP_002414826.1 CDS ade NC_011751.1 4323081 4324847 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4323081..4324847 Escherichia coli UMN026 7159248 YP_002414827.1 CDS ECUMN_4193 NC_011751.1 4324959 4325468 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group complement(4324959..4325468) Escherichia coli UMN026 7155697 YP_002414828.1 CDS ECUMN_4194 NC_011751.1 4325374 4325595 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4325374..4325595) Escherichia coli UMN026 7155443 YP_002414829.1 CDS uhpT NC_011751.1 4325605 4326996 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4325605..4326996) Escherichia coli UMN026 7155444 YP_002414830.1 CDS uhpC NC_011751.1 4327134 4328453 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4327134..4328453) Escherichia coli UMN026 7158173 YP_002414831.1 CDS uhpB NC_011751.1 4328463 4329965 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4328463..4329965) Escherichia coli UMN026 7158172 YP_002414832.1 CDS uhpA NC_011751.1 4329965 4330555 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4329965..4330555) Escherichia coli UMN026 7158171 YP_002414833.1 CDS ECUMN_4199 NC_011751.1 4330717 4332207 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4330717..4332207) Escherichia coli UMN026 7158170 YP_002414834.1 CDS ECUMN_4200 NC_011751.1 4332462 4333769 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4332462..4333769) Escherichia coli UMN026 7155445 YP_002414835.1 CDS ilvN NC_011751.1 4334022 4334312 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4334022..4334312) Escherichia coli UMN026 7155446 YP_002414836.1 CDS ilvB NC_011751.1 4334316 4336004 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2989782, 85242083, 92380929, 2989781; Product type e : enzyme; acetolactate synthase catalytic subunit complement(4334316..4336004) Escherichia coli UMN026 7156807 YP_002414837.1 CDS ivbL NC_011751.1 4336110 4336208 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; ilvB operon leader peptide complement(4336110..4336208) Escherichia coli UMN026 7156798 YP_002414838.1 CDS ECUMN_4204 NC_011751.1 4336482 4336640 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4336482..4336640 Escherichia coli UMN026 7156873 YP_002414839.1 CDS emrD NC_011751.1 4337142 4338326 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4337142..4338326 Escherichia coli UMN026 7155447 YP_002414840.1 CDS yidF NC_011751.1 4338334 4338831 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(4338334..4338831) Escherichia coli UMN026 7156242 YP_002414841.1 CDS yidG NC_011751.1 4338828 4339190 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4338828..4339190) Escherichia coli UMN026 7159256 YP_002414842.1 CDS yidH NC_011751.1 4339180 4339527 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4339180..4339527) Escherichia coli UMN026 7159257 YP_002414843.1 CDS yidI NC_011751.1 4339635 4340084 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4339635..4340084 Escherichia coli UMN026 7159258 YP_002414844.1 CDS yidJ NC_011751.1 4340131 4341624 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfatase/phosphatase complement(4340131..4341624) Escherichia coli UMN026 7159259 YP_002414845.1 CDS yidK NC_011751.1 4341621 4343336 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK complement(4341621..4343336) Escherichia coli UMN026 7159260 YP_002414846.1 CDS yidL NC_011751.1 4343473 4344396 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4343473..4344396 Escherichia coli UMN026 7159261 YP_002414847.1 CDS ECUMN_4213 NC_011751.1 4344393 4345715 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 6-phospho-glucosidase complement(4344393..4345715) Escherichia coli UMN026 7159262 YP_002414848.1 CDS ECUMN_4214 NC_011751.1 4345715 4347592 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative PTS system alpha-glucoside-specific EIICB component complement(4345715..4347592) Escherichia coli UMN026 7155448 YP_002414849.1 CDS yidP NC_011751.1 4347627 4348343 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4347627..4348343 Escherichia coli UMN026 7155449 YP_002414850.1 CDS yidE NC_011751.1 4348340 4350001 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356969; Product type pt : putative transporter; hypothetical protein complement(4348340..4350001) Escherichia coli UMN026 7159263 YP_002414851.1 CDS ibpB NC_011751.1 4350197 4350625 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4350197..4350625) Escherichia coli UMN026 7159255 YP_002414852.1 CDS ibpA NC_011751.1 4350737 4351150 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4350737..4351150) Escherichia coli UMN026 7156781 YP_002414853.1 CDS yidQ NC_011751.1 4351456 4351788 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4351456..4351788 Escherichia coli UMN026 7156780 YP_002414854.1 CDS yidR NC_011751.1 4351790 4353004 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4351790..4353004) Escherichia coli UMN026 7159264 YP_002414855.1 CDS cbrA NC_011751.1 4353084 4354205 D FAD/NAD(P)-binding domain; putative oxidoreductase 4353084..4354205 Escherichia coli UMN026 7159265 YP_002414856.1 CDS dgoT NC_011751.1 4354166 4355458 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type t : transporter; D-galactonate transporter complement(4354166..4355458) Escherichia coli UMN026 7155924 YP_002414857.1 CDS dgoD NC_011751.1 4355578 4356726 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; galactonate dehydratase complement(4355578..4356726) Escherichia coli UMN026 7156153 YP_002414858.1 CDS dgoA NC_011751.1 4356723 4357340 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4356723..4357340) Escherichia coli UMN026 7156150 YP_002414859.1 CDS dgoK NC_011751.1 4357324 4358202 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; 2-oxo-3-deoxygalactonate kinase complement(4357324..4358202) Escherichia coli UMN026 7156149 YP_002414860.1 CDS dgoR NC_011751.1 4358199 4358888 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 79020349; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(4358199..4358888) Escherichia coli UMN026 7156151 YP_002414861.1 CDS yidX NC_011751.1 4359049 4359822 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 4359049..4359822 Escherichia coli UMN026 7156152 YP_002414862.1 CDS yidA NC_011751.1 4359866 4360678 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4359866..4360678) Escherichia coli UMN026 7159266 YP_002414863.1 CDS yidB NC_011751.1 4360793 4361191 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4360793..4361191) Escherichia coli UMN026 7159251 YP_002414864.1 CDS gyrB NC_011751.1 4361431 4363845 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4361431..4363845) Escherichia coli UMN026 7159252 YP_002414865.1 CDS recF NC_011751.1 4363874 4364947 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4363874..4364947) Escherichia coli UMN026 7156632 YP_002414866.1 CDS dnaN NC_011751.1 4364947 4366047 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4364947..4366047) Escherichia coli UMN026 7157641 YP_002414867.1 CDS dnaA NC_011751.1 4366052 4367455 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(4366052..4367455) Escherichia coli UMN026 7156190 YP_002414868.1 CDS rpmH NC_011751.1 4368062 4368202 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4368062..4368202 Escherichia coli UMN026 7156183 YP_002414869.1 CDS rnpA NC_011751.1 4368219 4368578 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4368219..4368578 Escherichia coli UMN026 7157755 YP_002414870.1 CDS yidD NC_011751.1 4368542 4368799 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4368542..4368799 Escherichia coli UMN026 7157716 YP_002414871.1 CDS yidC NC_011751.1 4368802 4370448 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 4368802..4370448 Escherichia coli UMN026 7159254 YP_002414872.1 CDS trmE NC_011751.1 4370554 4371918 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4370554..4371918 Escherichia coli UMN026 7159253 YP_002414873.1 CDS tnaC NC_011751.1 4372160 4372234 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; tryptophanase leader peptide 4372160..4372234 Escherichia coli UMN026 7158114 YP_002414874.1 CDS tnaA NC_011751.1 4372455 4373870 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4372455..4373870 Escherichia coli UMN026 7158080 YP_002414875.1 CDS tnaB NC_011751.1 4373961 4375208 D tryptophan transporter of low affinity; tryptophan permease TnaB 4373961..4375208 Escherichia coli UMN026 7158078 YP_002414876.1 CDS mdtL NC_011751.1 4375341 4376516 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4375341..4376516 Escherichia coli UMN026 7158079 YP_002414877.1 CDS yidZ NC_011751.1 4376491 4377450 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4376491..4377450 Escherichia coli UMN026 7157089 YP_002414878.1 CDS yieE NC_011751.1 4377595 4378356 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphopantetheinyl transferase 4377595..4378356 Escherichia coli UMN026 7159267 YP_002414879.1 CDS yieF NC_011751.1 4378378 4378944 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766567; Product type e : enzyme; chromate reductase, Class I, flavoprotein 4378378..4378944 Escherichia coli UMN026 7159268 YP_002414880.1 CDS yieG NC_011751.1 4378998 4380335 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4378998..4380335) Escherichia coli UMN026 7159269 YP_002414881.1 CDS yieH NC_011751.1 4380502 4381167 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4380502..4381167 Escherichia coli UMN026 7159270 YP_002414882.1 CDS ECUMN_4247 NC_011751.1 4381304 4383712 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4381304..4383712) Escherichia coli UMN026 7159271 YP_002414883.1 CDS ECUMN_4248 NC_011751.1 4384018 4385205 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4384018..4385205 Escherichia coli UMN026 7155450 YP_002414884.1 CDS ECUMN_4249 NC_011751.1 4385675 4388194 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4385675..4388194) Escherichia coli UMN026 7155451 YP_002414885.1 CDS phoU NC_011751.1 4388592 4389317 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4388592..4389317) Escherichia coli UMN026 7155452 YP_002414886.1 CDS pstB NC_011751.1 4389332 4390105 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4389332..4390105) Escherichia coli UMN026 7157462 YP_002414887.1 CDS pstA NC_011751.1 4390196 4391086 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate permease PtsA complement(4390196..4391086) Escherichia coli UMN026 7157558 YP_002414888.1 CDS pstC NC_011751.1 4391086 4392045 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate permease PstC complement(4391086..4392045) Escherichia coli UMN026 7157557 YP_002414889.1 CDS pstS NC_011751.1 4392133 4393173 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133909, 2215649, 6321434, 6365894, 9228942, 9298646, 9671506; Product type t : transporter; phosphate ABC transporter periplasmic substrate-binding protein PstS complement(4392133..4393173) Escherichia coli UMN026 7157559 YP_002414890.1 CDS lpfD NC_011751.1 4393421 4394491 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12438351, 7721701, 16128397; Product type ps : putative structure; putative fimbrial protein LpfD complement(4393421..4394491) Escherichia coli UMN026 7157560 YP_002414891.1 CDS lpfC NC_011751.1 4394502 4397024 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7721701, 16128397; Product type pt : putative transporter; putative fimbrial usher complement(4394502..4397024) Escherichia coli UMN026 7157004 YP_002414892.1 CDS lfpB NC_011751.1 4397049 4397780 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16128397, 12438351; Product type pc : putative carrier; putative fimbrial chaperone protein complement(4397049..4397780) Escherichia coli UMN026 7157003 YP_002414893.1 CDS lpfA NC_011751.1 4397828 4398400 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16125910, 12438351; Product type ps : putative structure; putative major fimbrial subunit complement(4397828..4398400) Escherichia coli UMN026 7156975 YP_002414894.1 CDS glmS NC_011751.1 4398708 4400537 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4398708..4400537) Escherichia coli UMN026 7157002 YP_002414895.1 CDS glmU NC_011751.1 4400699 4402069 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4400699..4402069) Escherichia coli UMN026 7156546 YP_002414896.1 CDS atpC NC_011751.1 4402420 4402839 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(4402420..4402839) Escherichia coli UMN026 7156547 YP_002414897.1 CDS atpD NC_011751.1 4402860 4404242 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(4402860..4404242) Escherichia coli UMN026 7155835 YP_002414898.1 CDS atpG NC_011751.1 4404269 4405132 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(4404269..4405132) Escherichia coli UMN026 7155836 YP_002414899.1 CDS atpA NC_011751.1 4405183 4406724 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(4405183..4406724) Escherichia coli UMN026 7155839 YP_002414900.1 CDS atpH NC_011751.1 4406737 4407270 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(4406737..4407270) Escherichia coli UMN026 7155833 YP_002414901.1 CDS atpF NC_011751.1 4407285 4407755 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(4407285..4407755) Escherichia coli UMN026 7155840 YP_002414902.1 CDS atpE NC_011751.1 4407817 4408056 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(4407817..4408056) Escherichia coli UMN026 7155838 YP_002414903.1 CDS atpB NC_011751.1 4408103 4408918 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(4408103..4408918) Escherichia coli UMN026 7155837 YP_002414904.1 CDS atpI NC_011751.1 4408927 4409307 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4408927..4409307) Escherichia coli UMN026 7155834 YP_002414905.1 CDS gidB NC_011751.1 4409924 4410547 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4409924..4410547) Escherichia coli UMN026 7155841 YP_002414906.1 CDS gidA NC_011751.1 4410611 4412500 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(4410611..4412500) Escherichia coli UMN026 7156529 YP_002414907.1 CDS mioC NC_011751.1 4412879 4413322 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4412879..4413322) Escherichia coli UMN026 7156528 YP_002414908.1 CDS asnC NC_011751.1 4413412 4413870 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4413412..4413870) Escherichia coli UMN026 7157136 YP_002414909.1 CDS asnA NC_011751.1 4414022 4415014 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4414022..4415014 Escherichia coli UMN026 7155815 YP_002414910.1 CDS yieM NC_011751.1 4415019 4416470 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4415019..4416470) Escherichia coli UMN026 7155813 YP_002414911.1 CDS ravA NC_011751.1 4416464 4417960 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4416464..4417960) Escherichia coli UMN026 7159272 YP_002414912.1 CDS trkD NC_011751.1 4418183 4420051 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4418183..4420051 Escherichia coli UMN026 7157618 YP_002414913.1 CDS rbsD NC_011751.1 4420218 4420637 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4420218..4420637 Escherichia coli UMN026 7158109 YP_002414914.1 CDS rbsA NC_011751.1 4420645 4422150 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4420645..4422150 Escherichia coli UMN026 7157625 YP_002414915.1 CDS rbsC NC_011751.1 4422155 4423120 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease protein 4422155..4423120 Escherichia coli UMN026 7157622 YP_002414916.1 CDS rbsB NC_011751.1 4423145 4424035 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4423145..4424035 Escherichia coli UMN026 7157624 YP_002414917.1 CDS rbsK NC_011751.1 4424161 4425090 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4424161..4425090 Escherichia coli UMN026 7157623 YP_002414918.1 CDS rbsR NC_011751.1 4425094 4426086 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4425094..4426086 Escherichia coli UMN026 7157626 YP_002414919.1 CDS hsrA NC_011751.1 4426052 4427479 R Evidence 2b : Function of strongly homologous gene; PubMedId : 20218988, 12107133; Product type t : transporter; multidrug or homocysteine efflux system complement(4426052..4427479) Escherichia coli UMN026 7157627 YP_002414920.1 CDS yieP NC_011751.1 4427502 4428194 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(4427502..4428194) Escherichia coli UMN026 7156725 YP_002414921.1 CDS hdfR NC_011751.1 4433993 4434832 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4433993..4434832) Escherichia coli UMN026 7155593 YP_002414922.1 CDS yifE NC_011751.1 4434951 4435289 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4434951..4435289 Escherichia coli UMN026 7156647 YP_002414923.1 CDS yifB NC_011751.1 4435315 4436865 R among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease complement(4435315..4436865) Escherichia coli UMN026 7159275 YP_002414924.1 CDS ilvL NC_011751.1 4437188 4437286 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; ilvG operon leader peptide 4437188..4437286 Escherichia coli UMN026 7159274 YP_002414925.1 CDS ilvG NC_011751.1 4437426 4439072 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4437426..4439072 Escherichia coli UMN026 7156805 YP_002414926.1 CDS ilvM NC_011751.1 4439069 4439332 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92332418, 92380929, 1569580, 3550695, 3897211; Product type e : enzyme; acetolactate synthase 2 regulatory subunit 4439069..4439332 Escherichia coli UMN026 7156802 YP_002414927.1 CDS ilvE NC_011751.1 4439352 4440281 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4439352..4440281 Escherichia coli UMN026 7156806 YP_002414928.1 CDS ilvD NC_011751.1 4440346 4442196 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4440346..4442196 Escherichia coli UMN026 7156801 YP_002414929.1 CDS ilvA NC_011751.1 4442199 4443743 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4442199..4443743 Escherichia coli UMN026 7156800 YP_002414930.1 CDS ilvY NC_011751.1 4443740 4444714 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4443740..4444714) Escherichia coli UMN026 7156797 YP_002414931.1 CDS ilvC NC_011751.1 4444780 4446255 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4444780..4446255 Escherichia coli UMN026 7156808 YP_002414932.1 CDS ppiC NC_011751.1 4446301 4446582 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94215709, 7878732, 7925971, 8163020; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase C complement(4446301..4446582) Escherichia coli UMN026 7156799 YP_002414933.1 CDS rep NC_011751.1 4446669 4448690 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4446669..4448690 Escherichia coli UMN026 7157507 YP_002414934.1 CDS gpp NC_011751.1 4448737 4450221 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4448737..4450221) Escherichia coli UMN026 7157652 YP_002414935.1 CDS rhlB NC_011751.1 4450357 4451622 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4450357..4451622) Escherichia coli UMN026 7156606 YP_002414936.1 CDS trxA NC_011751.1 4451753 4452082 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 91154193, 92250497, 99175138, 10489448, 1094461, 10947986, 1561103, 2181145, 2193685, 3891733, 4616096, 4883076, 6098320, 6099324, 7812718, 8098620, 8253691; Product type c : carrier; thioredoxin 4451753..4452082 Escherichia coli UMN026 7157675 YP_002414937.1 CDS rhoL NC_011751.1 4452223 4452324 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; putative rho operon leader peptide 4452223..4452324 Escherichia coli UMN026 7158129 YP_002414938.1 CDS rho NC_011751.1 4452409 4453668 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4452409..4453668 Escherichia coli UMN026 7157678 YP_002414939.1 CDS ECUMN_4308 NC_011751.1 4453678 4453896 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4453678..4453896 Escherichia coli UMN026 7157677 YP_002414940.1 CDS rfe NC_011751.1 4453908 4455011 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92114763, 94245613, 94292435, 10629198, 11024259, 11700352, 11832520, 1722555, 1730666; Product type e : enzyme; UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase 4453908..4455011 Escherichia coli UMN026 7155453 YP_002414941.1 CDS wzzE NC_011751.1 4455023 4456069 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4455023..4456069 Escherichia coli UMN026 7157660 YP_002414942.1 CDS rffE NC_011751.1 4456125 4457255 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 94042873, 11106477, 7559340, 8170390, 8226648; Product type e : enzyme; UDP-N-acetyl glucosamine-2-epimerase 4456125..4457255 Escherichia coli UMN026 7158241 YP_002414943.1 CDS wecC NC_011751.1 4457252 4458514 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4457252..4458514 Escherichia coli UMN026 7157664 YP_002414944.1 CDS rffG NC_011751.1 4458514 4459581 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086930, 90212314, 90337949, 92112804, 92174908, 94018634, 94042873, 7559340; Product type e : enzyme; dTDP-glucose 4,6-dehydratase 4458514..4459581 Escherichia coli UMN026 7157663 YP_002414945.1 CDS rffH NC_011751.1 4459600 4460481 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292435, 96032389; Product type e : enzyme; glucose-1-phosphate thymidylyltransferase 4459600..4460481 Escherichia coli UMN026 7157665 YP_002414946.1 CDS rffC NC_011751.1 4460459 4461133 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 8366065; Product type e : enzyme; TDP-fucosamine acetyltransferase 4460459..4461133 Escherichia coli UMN026 7157666 YP_002414947.1 CDS rffA NC_011751.1 4461138 4462268 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4461138..4462268 Escherichia coli UMN026 7157662 YP_002414948.1 CDS wzxE NC_011751.1 4462270 4463520 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12621029, 20044778; Product type t : transporter; O-antigen translocase 4462270..4463520 Escherichia coli UMN026 7157661 YP_002414949.1 CDS rffT NC_011751.1 4463517 4464596 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4463517..4464596 Escherichia coli UMN026 7158239 YP_002414950.1 CDS wzyE NC_011751.1 4464593 4465945 D enterobacterial common antigen polymerase; putative common antigen polymerase 4464593..4465945 Escherichia coli UMN026 7157668 YP_002414951.1 CDS rffM NC_011751.1 4465948 4466688 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086874, 90337949, 92112804; Product type e : enzyme; putative UDP-N-acetyl-D-mannosaminuronic acid transferase 4465948..4466688 Escherichia coli UMN026 7158240 YP_002414952.1 CDS yifK NC_011751.1 4466879 4468264 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK 4466879..4468264 Escherichia coli UMN026 7157667 YP_002414953.1 CDS aslB NC_011751.1 4468950 4470185 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11222759, 2180918, 12419807, 14749327; Product type pr : putative regulator; regulator of arylsulfatase activity 4468950..4470185 Escherichia coli UMN026 7155597 YP_002414954.1 CDS aslA NC_011751.1 4470287 4471942 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16766528, 92358234, 15477040; Product type e : enzyme; arylsulfatase-like enzyme complement(4470287..4471942) Escherichia coli UMN026 7155811 YP_002414955.1 CDS hemY NC_011751.1 4472621 4473817 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89041586; Product type pe : putative enzyme; putative protoheme IX biogenesis protein complement(4472621..4473817) Escherichia coli UMN026 7157856 YP_002414956.1 CDS hemX NC_011751.1 4473820 4475031 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89098348, 92358234, 3054815, 3062586, 9298646; Product type pe : putative enzyme; putative uroporphyrinogen III C-methyltransferase complement(4473820..4475031) Escherichia coli UMN026 7156661 YP_002414957.1 CDS hemD NC_011751.1 4475053 4475793 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4475053..4475793) Escherichia coli UMN026 7156660 YP_002414958.1 CDS hemC NC_011751.1 4475790 4476731 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4475790..4476731) Escherichia coli UMN026 7156653 YP_002414959.1 CDS cyaA NC_011751.1 4477118 4479664 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4477118..4479664 Escherichia coli UMN026 7156652 YP_002414960.1 CDS cyaY NC_011751.1 4479704 4480024 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4479704..4480024) Escherichia coli UMN026 7156060 YP_002414961.1 CDS yifL NC_011751.1 4480490 4480693 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4480490..4480693 Escherichia coli UMN026 7156061 YP_002414962.1 CDS dapF NC_011751.1 4480730 4481554 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4480730..4481554 Escherichia coli UMN026 7159277 YP_002414963.1 CDS yigA NC_011751.1 4481551 4482258 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4481551..4482258 Escherichia coli UMN026 7156111 YP_002414964.1 CDS xerC NC_011751.1 4482255 4483151 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4482255..4483151 Escherichia coli UMN026 7159278 YP_002414965.1 CDS yigB NC_011751.1 4483151 4483867 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4483151..4483867 Escherichia coli UMN026 7158246 YP_002414966.1 CDS uvrD NC_011751.1 4483951 4486113 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4483951..4486113 Escherichia coli UMN026 7159279 YP_002414967.1 CDS yigE NC_011751.1 4487143 4487907 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4487143..4487907) Escherichia coli UMN026 7155455 YP_002414968.1 CDS corA NC_011751.1 4488277 4489227 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4488277..4489227 Escherichia coli UMN026 7159280 YP_002414969.1 CDS yigF NC_011751.1 4489270 4489650 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784; Product type pm : putative membrane component; hypothetical protein complement(4489270..4489650) Escherichia coli UMN026 7155999 YP_002414970.1 CDS yigG NC_011751.1 4489664 4490044 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4489664..4490044) Escherichia coli UMN026 7159281 YP_002414971.1 CDS rarD NC_011751.1 4490139 4491029 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative chloramphenicol resistance permease complement(4490139..4491029) Escherichia coli UMN026 7159282 YP_002414972.1 CDS yigI NC_011751.1 4491081 4491548 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4491081..4491548) Escherichia coli UMN026 7157617 YP_002414973.1 CDS pldA NC_011751.1 4491713 4492582 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4491713..4492582 Escherichia coli UMN026 7159283 YP_002414974.1 CDS recQ NC_011751.1 4492715 4494544 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4492715..4494544 Escherichia coli UMN026 7157470 YP_002414975.1 CDS rhtC NC_011751.1 4494608 4495228 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596, 3027506; Product type t : transporter; threonine efflux system 4494608..4495228 Escherichia coli UMN026 7157646 YP_002414976.1 CDS rhtB NC_011751.1 4495290 4495910 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596; Product type t : transporter; homoserine/homoserine lactone efflux protein complement(4495290..4495910) Escherichia coli UMN026 7157681 YP_002414977.1 CDS pldB NC_011751.1 4496021 4497043 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4496021..4497043 Escherichia coli UMN026 7157680 YP_002414978.1 CDS yigL NC_011751.1 4497051 4497851 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase 4497051..4497851 Escherichia coli UMN026 7157471 YP_002414979.1 CDS yigM NC_011751.1 4497927 4498826 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4497927..4498826 Escherichia coli UMN026 7159284 YP_002414980.1 CDS metR NC_011751.1 4498714 4499667 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90384950, 96303520, 2205852, 2643109; Product type r : regulator; DNA-binding transcriptional activator, homocysteine-binding complement(4498714..4499667) Escherichia coli UMN026 7159285 YP_002414981.1 CDS metE NC_011751.1 4499903 4502164 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4499903..4502164 Escherichia coli UMN026 7157113 YP_002414982.1 CDS ysgA NC_011751.1 4502203 4503018 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12676709; Product type pe : putative enzyme; putative hydrolase complement(4502203..4503018) Escherichia coli UMN026 7157103 YP_002414983.1 CDS udp NC_011751.1 4503280 4504041 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4503280..4504041 Escherichia coli UMN026 7159665 YP_002414984.1 CDS rmuC NC_011751.1 4504182 4505609 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4504182..4505609 Escherichia coli UMN026 7158163 YP_002414985.1 CDS ubiE NC_011751.1 4505704 4506459 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4505704..4506459 Escherichia coli UMN026 7157704 YP_002414986.1 CDS yigP NC_011751.1 4506473 4507078 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4506473..4507078 Escherichia coli UMN026 7158156 YP_002414987.1 CDS ubiB NC_011751.1 4507075 4508715 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 4507075..4508715 Escherichia coli UMN026 7159286 YP_002414988.1 CDS tatA NC_011751.1 4508794 4509063 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4508794..4509063 Escherichia coli UMN026 7158153 YP_002414989.1 CDS tatB NC_011751.1 4509067 4509582 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4509067..4509582 Escherichia coli UMN026 7158025 YP_002414990.1 CDS tatC NC_011751.1 4509585 4510361 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4509585..4510361 Escherichia coli UMN026 7158026 YP_002414991.1 CDS tatD NC_011751.1 4510403 4511185 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4510403..4511185 Escherichia coli UMN026 7158027 YP_002414992.1 CDS rfaH NC_011751.1 4511182 4511670 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92011415, 92250420, 92261317, 1584020, 12007406; Product type r : regulator; transcriptional activator RfaH complement(4511182..4511670) Escherichia coli UMN026 7158028 YP_002414993.1 CDS ubiD NC_011751.1 4511837 4513330 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate decarboxylase 4511837..4513330 Escherichia coli UMN026 7157654 YP_002414994.1 CDS fre NC_011751.1 4513376 4514077 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4513376..4514077 Escherichia coli UMN026 7158155 YP_002414995.1 CDS fadA NC_011751.1 4514268 4515431 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4514268..4515431) Escherichia coli UMN026 7156438 YP_002414996.1 CDS fadB NC_011751.1 4515441 4517630 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4515441..4517630) Escherichia coli UMN026 7156302 YP_002414997.1 CDS pepQ NC_011751.1 4517820 4519151 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4517820..4519151 Escherichia coli UMN026 7156303 YP_002414998.1 CDS yigZ NC_011751.1 4519151 4519765 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15103642; Product type pf : putative factor; hypothetical protein 4519151..4519765 Escherichia coli UMN026 7157416 YP_002414999.1 CDS trkH NC_011751.1 4519804 4521255 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100357, 2243799, 7896723; Product type t : transporter; potassium transporter 4519804..4521255 Escherichia coli UMN026 7159287 YP_002415000.1 CDS hemG NC_011751.1 4521267 4521812 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4521267..4521812 Escherichia coli UMN026 7158110 YP_002415001.1 CDS mobB NC_011751.1 4527390 4527902 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4527390..4527902) Escherichia coli UMN026 7155562 YP_002415002.1 CDS mobA NC_011751.1 4527899 4528483 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4527899..4528483) Escherichia coli UMN026 7157151 YP_002415003.1 CDS yihD NC_011751.1 4528553 4528822 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4528553..4528822 Escherichia coli UMN026 7157150 YP_002415004.1 CDS yihE NC_011751.1 4528899 4529885 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4528899..4529885 Escherichia coli UMN026 7159289 YP_002415005.1 CDS dsbA NC_011751.1 4529902 4530528 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12498799, 93264419, 94016574, 94206930, 99298180, 10210188, 1429594, 1740115, 1934062, 8413591, 8494885, 8521518, 9194175, 9298646, 9300489, 9572841, 9600841, 9655827; Product type e : enzyme; periplasmic protein disulfide isomerase I 4529902..4530528 Escherichia coli UMN026 7159290 YP_002415006.1 CDS yihF NC_011751.1 4530683 4532113 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4530683..4532113 Escherichia coli UMN026 7156202 YP_002415007.1 CDS yihG NC_011751.1 4532154 4533086 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase complement(4532154..4533086) Escherichia coli UMN026 7159291 YP_002415008.1 CDS polA NC_011751.1 4533450 4536236 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4533450..4536236 Escherichia coli UMN026 7159292 YP_002415009.1 CDS engB NC_011751.1 4536618 4537214 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4536618..4537214) Escherichia coli UMN026 7157963 YP_002415010.1 CDS yihI NC_011751.1 4537832 4538341 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4537832..4538341 Escherichia coli UMN026 7156045 YP_002415011.1 CDS hemN NC_011751.1 4538530 4539903 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4538530..4539903 Escherichia coli UMN026 7159293 YP_002415012.1 CDS glnG NC_011751.1 4540315 4541724 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4540315..4541724) Escherichia coli UMN026 7156659 YP_002415013.1 CDS glnL NC_011751.1 4541736 4542785 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4541736..4542785) Escherichia coli UMN026 7156552 YP_002415014.1 CDS glnA NC_011751.1 4542959 4544368 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4542959..4544368) Escherichia coli UMN026 7156555 YP_002415015.1 CDS ECUMN_4394 NC_011751.1 4544502 4544648 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4544502..4544648) Escherichia coli UMN026 7156548 YP_002415016.1 CDS bipA NC_011751.1 4544741 4546564 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642082, 7783627, 9298646, 9622352; Product type f : factor; GTP-binding protein 4544741..4546564 Escherichia coli UMN026 7155456 YP_002415017.1 CDS yihL NC_011751.1 4546781 4547491 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4546781..4547491 Escherichia coli UMN026 7155882 YP_002415018.1 CDS ECUMN_4398 NC_011751.1 4547864 4548910 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family complement(4547864..4548910) Escherichia coli UMN026 7159295 YP_002415019.1 CDS ECUMN_4399 NC_011751.1 4548730 4549077 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS3 family complement(4548730..4549077) Escherichia coli UMN026 7155457 YP_002415020.1 CDS yihN NC_011751.1 4549842 4551107 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4549842..4551107 Escherichia coli UMN026 7159296 YP_002415021.1 CDS ompL NC_011751.1 4551199 4551891 R porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L complement(4551199..4551891) Escherichia coli UMN026 7159297 YP_002415022.1 CDS yihO NC_011751.1 4551958 4553361 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(4551958..4553361) Escherichia coli UMN026 7157347 YP_002415023.1 CDS yihP NC_011751.1 4553402 4554808 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(4553402..4554808) Escherichia coli UMN026 7159298 YP_002415024.1 CDS yihQ NC_011751.1 4554833 4556869 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294295; Product type e : enzyme; alpha-glucosidase complement(4554833..4556869) Escherichia coli UMN026 7159299 YP_002415025.1 CDS yihR NC_011751.1 4557074 4557985 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldose-1-epimerase complement(4557074..4557985) Escherichia coli UMN026 7159300 YP_002415026.1 CDS yihS NC_011751.1 4558044 4559285 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glucosamine isomerase complement(4558044..4559285) Escherichia coli UMN026 7159301 YP_002415027.1 CDS yihT NC_011751.1 4559301 4560179 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldolase complement(4559301..4560179) Escherichia coli UMN026 7159302 YP_002415028.1 CDS yihU NC_011751.1 4560203 4561099 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(4560203..4561099) Escherichia coli UMN026 7159303 YP_002415029.1 CDS yihV NC_011751.1 4561267 4562163 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar kinase 4561267..4562163 Escherichia coli UMN026 7159304 YP_002415030.1 CDS yihW NC_011751.1 4562197 4562982 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4562197..4562982 Escherichia coli UMN026 7159305 YP_002415031.1 CDS yihX NC_011751.1 4563081 4563680 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; phosphatase 4563081..4563680 Escherichia coli UMN026 7159306 YP_002415032.1 CDS rbn NC_011751.1 4563674 4564546 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4563674..4564546 Escherichia coli UMN026 7159307 YP_002415033.1 CDS dtd NC_011751.1 4564543 4564980 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA (Tyr) deacylase 4564543..4564980 Escherichia coli UMN026 7157621 YP_002415034.1 CDS yiiD NC_011751.1 4564977 4565966 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase 4564977..4565966 Escherichia coli UMN026 7156211 YP_002415035.1 CDS ECUMN_4416 NC_011751.1 4566343 4568196 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4566343..4568196 Escherichia coli UMN026 7159308 YP_002415036.1 CDS ECUMN_4417 NC_011751.1 4568246 4568347 D Evidence 6 : Doubtful CDS; hypothetical protein 4568246..4568347 Escherichia coli UMN026 7155459 YP_002415037.1 CDS yiiE NC_011751.1 4568892 4569110 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4568892..4569110 Escherichia coli UMN026 7155460 YP_002415038.1 CDS yiiF NC_011751.1 4569329 4569571 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4569329..4569571 Escherichia coli UMN026 7159309 YP_002415039.1 CDS fdhE NC_011751.1 4569753 4570682 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4569753..4570682) Escherichia coli UMN026 7159310 YP_002415040.1 CDS fdoI NC_011751.1 4570679 4571314 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4570679..4571314) Escherichia coli UMN026 7156314 YP_002415041.1 CDS fdoH NC_011751.1 4571311 4572213 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91317715, 8522521, 9852007; Product type c : carrier; formate dehydrogenase-O, Fe-S subunit complement(4571311..4572213) Escherichia coli UMN026 7156321 YP_002415042.1 CDS fdoG NC_011751.1 4572226 4575276 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-O, large subunit complement(4572226..4575276) Escherichia coli UMN026 7156320 YP_002415043.1 CDS fdhD NC_011751.1 4575470 4576303 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4575470..4576303 Escherichia coli UMN026 7156319 YP_002415044.1 CDS ECUMN_4428 NC_011751.1 4577436 4578830 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative glycoporin 4577436..4578830 Escherichia coli UMN026 7159311 YP_002415045.1 CDS yiiL NC_011751.1 4578871 4579185 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078; Product type e : enzyme; L-rhamnose mutarotase complement(4578871..4579185) Escherichia coli UMN026 7155461 YP_002415046.1 CDS rhaD NC_011751.1 4579195 4580019 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90128204, 93374854, 8396120; Product type e : enzyme; rhamnulose-1-phosphate aldolase complement(4579195..4580019) Escherichia coli UMN026 7159312 YP_002415047.1 CDS rhaA NC_011751.1 4580102 4581361 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4580102..4581361) Escherichia coli UMN026 7157671 YP_002415048.1 CDS rhaB NC_011751.1 4581358 4582827 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4581358..4582827) Escherichia coli UMN026 7157669 YP_002415049.1 CDS rhaS NC_011751.1 4583115 4583951 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4583115..4583951 Escherichia coli UMN026 7157670 YP_002415050.1 CDS rhaR NC_011751.1 4583935 4584873 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4583935..4584873 Escherichia coli UMN026 7157673 YP_002415051.1 CDS rhaT NC_011751.1 4584870 4585904 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4584870..4585904) Escherichia coli UMN026 7157672 YP_002415052.1 CDS sodA NC_011751.1 4586189 4586809 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4586189..4586809 Escherichia coli UMN026 7157674 YP_002415053.1 CDS kdgT NC_011751.1 4587087 4588052 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4587087..4588052 Escherichia coli UMN026 7157945 YP_002415054.1 CDS yiiM NC_011751.1 4588201 4588875 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4588201..4588875 Escherichia coli UMN026 7156889 YP_002415055.1 CDS cpxA NC_011751.1 4588980 4590353 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4588980..4590353) Escherichia coli UMN026 7159313 YP_002415056.1 CDS cpxR NC_011751.1 4590350 4591048 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4590350..4591048) Escherichia coli UMN026 7156005 YP_002415057.1 CDS cpxP NC_011751.1 4591198 4591698 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4591198..4591698 Escherichia coli UMN026 7156007 YP_002415058.1 CDS fieF NC_011751.1 4591847 4592749 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4591847..4592749 Escherichia coli UMN026 7156006 YP_002415059.1 CDS pfkA NC_011751.1 4592930 4593892 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4592930..4593892 Escherichia coli UMN026 7156353 YP_002415060.1 CDS sbp NC_011751.1 4594212 4595201 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91161616, 2002055, 3158524, 8774726, 9298646; Product type t : transporter; sulfate transporter subunit 4594212..4595201 Escherichia coli UMN026 7157419 YP_002415061.1 CDS cdh NC_011751.1 4595308 4596063 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86008270, 2995360, 3158524; Product type e : enzyme; CDP-diacylglycerol pyrophosphatase 4595308..4596063 Escherichia coli UMN026 7157876 YP_002415062.1 CDS tpiA NC_011751.1 4596118 4596885 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4596118..4596885) Escherichia coli UMN026 7155938 YP_002415063.1 CDS yiiQ NC_011751.1 4596993 4597592 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4596993..4597592) Escherichia coli UMN026 7158098 YP_002415064.1 CDS yiiR NC_011751.1 4597693 4598133 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4597693..4598133 Escherichia coli UMN026 7159314 YP_002415065.1 CDS yiiS NC_011751.1 4598345 4598644 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4598345..4598644 Escherichia coli UMN026 7159315 YP_002415066.1 CDS yiiT NC_011751.1 4598671 4599099 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4598671..4599099 Escherichia coli UMN026 7159316 YP_002415067.1 CDS fpr NC_011751.1 4599104 4599850 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93194782, 94092163, 95050480, 95362685, 1400248, 2834327, 7961651, 8449868, 9149148; Product type e : enzyme; ferredoxin-NADP reductase complement(4599104..4599850) Escherichia coli UMN026 7159317 YP_002415068.1 CDS glpX NC_011751.1 4599947 4600957 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4599947..4600957) Escherichia coli UMN026 7156432 YP_002415069.1 CDS glpK NC_011751.1 4601092 4602600 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4601092..4602600) Escherichia coli UMN026 7156572 YP_002415070.1 CDS glpF NC_011751.1 4602623 4603468 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12629974, 12948772, 14646142, 15004242, 90094250, 92210584, 11039922, 11101882, 11226336, 11964478, 1372899, 2544860, 6998951; Product type t : transporter; glycerol facilitator complement(4602623..4603468) Escherichia coli UMN026 7156568 YP_002415071.1 CDS yiiU NC_011751.1 4603893 4604138 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4603893..4604138 Escherichia coli UMN026 7156566 YP_002415072.1 CDS ECUMN_4457 NC_011751.1 4604177 4604893 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4604177..4604893) Escherichia coli UMN026 7159318 YP_002415073.1 CDS ECUMN_4458 NC_011751.1 4604926 4605612 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4604926..4605612) Escherichia coli UMN026 7155462 YP_002415074.1 CDS rraA NC_011751.1 4605660 4606145 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4605660..4606145) Escherichia coli UMN026 7155463 YP_002415075.1 CDS menA NC_011751.1 4606238 4607164 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4606238..4607164) Escherichia coli UMN026 7157788 YP_002415076.1 CDS hslU NC_011751.1 4607231 4608562 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4607231..4608562) Escherichia coli UMN026 7157093 YP_002415077.1 CDS hslV NC_011751.1 4608572 4609102 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4608572..4609102) Escherichia coli UMN026 7156723 YP_002415078.1 CDS ftsN NC_011751.1 4609195 4610154 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9282742, 93285993, 8509333; Product type cp : cell process; essential cell division protein FtsN complement(4609195..4610154) Escherichia coli UMN026 7156724 YP_002415079.1 CDS cytR NC_011751.1 4610246 4611271 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4610246..4611271) Escherichia coli UMN026 7156463 YP_002415080.1 CDS priA NC_011751.1 4611427 4613625 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4611427..4613625) Escherichia coli UMN026 7156096 YP_002415081.1 CDS rpmE NC_011751.1 4613828 4614040 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4613828..4614040 Escherichia coli UMN026 7157522 YP_002415082.1 CDS yiiX NC_011751.1 4614101 4614709 R member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase complement(4614101..4614709) Escherichia coli UMN026 7157752 YP_002415083.1 CDS metJ NC_011751.1 4614769 4615224 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4614769..4615224) Escherichia coli UMN026 7159319 YP_002415084.1 CDS metB NC_011751.1 4615363 4616523 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87326410, 90148970, 3307782, 6361020, 9843488; Product type e : enzyme; cystathionine gamma-synthase, PLP-dependent 4615363..4616523 Escherichia coli UMN026 7157108 YP_002415085.1 CDS metL NC_011751.1 4616526 4618958 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4616526..4618958 Escherichia coli UMN026 7157101 YP_002415086.1 CDS ECUMN_4471 NC_011751.1 4618922 4620052 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4618922..4620052) Escherichia coli UMN026 7157110 YP_002415087.1 CDS ECUMN_4472 NC_011751.1 4620185 4621738 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphoesterase 4620185..4621738 Escherichia coli UMN026 7155464 YP_002415088.1 CDS metF NC_011751.1 4622120 4623010 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4622120..4623010 Escherichia coli UMN026 7155465 YP_002415089.1 CDS katG NC_011751.1 4623339 4625519 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90292022, 94209230, 3045098; Product type e : enzyme; catalase/hydroperoxidase HPI(I) 4623339..4625519 Escherichia coli UMN026 7157104 YP_002415090.1 CDS yijE NC_011751.1 4625612 4626517 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease 4625612..4626517 Escherichia coli UMN026 7156882 YP_002415091.1 CDS yijF NC_011751.1 4626544 4627161 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4626544..4627161) Escherichia coli UMN026 7159321 YP_002415092.1 CDS gldA NC_011751.1 4627492 4628595 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4627492..4628595) Escherichia coli UMN026 7159322 YP_002415093.1 CDS fsaB NC_011751.1 4628606 4629268 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4628606..4629268) Escherichia coli UMN026 7156536 YP_002415094.1 CDS ptsA NC_011751.1 4629280 4631781 R Evidence 2b : Function of strongly homologous gene; PubMedId : 95291446, 7773398; Product type t : transporter; putative PTS system Hpr component/enzyme I component/enzyme IIA component complement(4629280..4631781) Escherichia coli UMN026 7156453 YP_002415095.1 CDS frwC NC_011751.1 4632090 4633169 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative fructose-like permease EIIC subunit 2 4632090..4633169 Escherichia coli UMN026 7157565 YP_002415096.1 CDS frwB NC_011751.1 4633184 4633504 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB 4633184..4633504 Escherichia coli UMN026 7156450 YP_002415097.1 CDS pflD NC_011751.1 4633555 4635852 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 4633555..4635852 Escherichia coli UMN026 7156449 YP_002415098.1 CDS pflC NC_011751.1 4635818 4636696 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95291446, 14673546, 7773398; Product type e : enzyme; pyruvate formate lyase II activase 4635818..4636696 Escherichia coli UMN026 7157424 YP_002415099.1 CDS frwD NC_011751.1 4636698 4637039 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative fructose-like phosphotransferase EIIB subunit 3 4636698..4637039 Escherichia coli UMN026 7157423 YP_002415100.1 CDS yijO NC_011751.1 4637026 4637877 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(4637026..4637877) Escherichia coli UMN026 7156451 YP_002415101.1 CDS yijP NC_011751.1 4638103 4639836 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10456927; Product type pm : putative membrane component; hypothetical protein complement(4638103..4639836) Escherichia coli UMN026 7159323 YP_002415102.1 CDS ppc NC_011751.1 4640019 4642670 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4640019..4642670) Escherichia coli UMN026 7159324 YP_002415103.1 CDS argE NC_011751.1 4643082 4644233 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4643082..4644233) Escherichia coli UMN026 7157498 YP_002415104.1 CDS argC NC_011751.1 4644387 4645391 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4644387..4645391 Escherichia coli UMN026 7155772 YP_002415105.1 CDS argB NC_011751.1 4645402 4646175 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4645402..4646175 Escherichia coli UMN026 7155770 YP_002415106.1 CDS argH NC_011751.1 4646236 4647609 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4646236..4647609 Escherichia coli UMN026 7155769 YP_002415107.1 CDS oxyR NC_011751.1 4647876 4648793 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4647876..4648793 Escherichia coli UMN026 7157371 YP_002415108.1 CDS sthA NC_011751.1 4648776 4650176 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4648776..4650176) Escherichia coli UMN026 7157370 YP_002415109.1 CDS fabR NC_011751.1 4650454 4651158 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4650454..4651158 Escherichia coli UMN026 7157996 YP_002415110.1 CDS yijD NC_011751.1 4651158 4651517 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4651158..4651517 Escherichia coli UMN026 7156300 YP_002415111.1 CDS trmA NC_011751.1 4651557 4652657 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4651557..4652657) Escherichia coli UMN026 7159320 YP_002415112.1 CDS btuB NC_011751.1 4653026 4654870 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4653026..4654870 Escherichia coli UMN026 7158111 YP_002415113.1 CDS murI NC_011751.1 4654803 4655672 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4654803..4655672 Escherichia coli UMN026 7155894 YP_002415114.1 CDS murB NC_011751.1 4661194 4662222 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4661194..4662222 Escherichia coli UMN026 7155563 YP_002415115.1 CDS birA NC_011751.1 4662219 4663184 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4662219..4663184 Escherichia coli UMN026 7157202 YP_002415116.1 CDS coaA NC_011751.1 4663213 4664163 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4663213..4664163) Escherichia coli UMN026 7155883 YP_002415117.1 CDS tufB NC_011751.1 4665081 4666265 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4665081..4666265 Escherichia coli UMN026 7155605 YP_002415118.1 CDS secE NC_011751.1 4666495 4666878 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4666495..4666878 Escherichia coli UMN026 7158140 YP_002415119.1 CDS nusG NC_011751.1 4666880 4667425 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4666880..4667425 Escherichia coli UMN026 7157888 YP_002415120.1 CDS rplK NC_011751.1 4667584 4668012 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4667584..4668012 Escherichia coli UMN026 7157340 YP_002415121.1 CDS rplA NC_011751.1 4668016 4668720 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4668016..4668720 Escherichia coli UMN026 7157733 YP_002415122.1 CDS rplJ NC_011751.1 4669012 4669509 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4669012..4669509 Escherichia coli UMN026 7157725 YP_002415123.1 CDS rplL NC_011751.1 4669576 4669941 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4669576..4669941 Escherichia coli UMN026 7157732 YP_002415124.1 CDS rpoB NC_011751.1 4670261 4674289 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4670261..4674289 Escherichia coli UMN026 7157734 YP_002415125.1 CDS rpoC NC_011751.1 4674366 4678589 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4674366..4678589 Escherichia coli UMN026 7157758 YP_002415126.1 CDS htrC NC_011751.1 4678803 4679342 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264341, 92021792, 2160943; Product type f : factor; heat shock protein 4678803..4679342 Escherichia coli UMN026 7157759 YP_002415127.1 CDS thiH NC_011751.1 4679752 4680885 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4679752..4680885) Escherichia coli UMN026 7157981 YP_002415128.1 CDS thiG NC_011751.1 4680882 4681652 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4680882..4681652) Escherichia coli UMN026 7158057 YP_002415129.1 CDS thiS NC_011751.1 4681654 4681854 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(4681654..4681854) Escherichia coli UMN026 7158056 YP_002415130.1 CDS thiF NC_011751.1 4681838 4682593 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8432721, 94089392, 98298179, 10082377, 9632726; Product type e : enzyme; thiamin (thiazole moiety) biosynthesis protein complement(4681838..4682593) Escherichia coli UMN026 7158063 YP_002415131.1 CDS thiE NC_011751.1 4682586 4683221 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4682586..4683221) Escherichia coli UMN026 7158055 YP_002415132.1 CDS thiC NC_011751.1 4683221 4685116 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4683221..4685116) Escherichia coli UMN026 7158054 YP_002415133.1 CDS rsd NC_011751.1 4685349 4685825 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4685349..4685825) Escherichia coli UMN026 7158052 YP_002415134.1 CDS nudC NC_011751.1 4685920 4686693 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4685920..4686693 Escherichia coli UMN026 7157791 YP_002415135.1 CDS hemE NC_011751.1 4686733 4687797 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4686733..4687797 Escherichia coli UMN026 7157317 YP_002415136.1 CDS nfi NC_011751.1 4687807 4688478 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4687807..4688478 Escherichia coli UMN026 7156654 YP_002415137.1 CDS yjaG NC_011751.1 4688521 4689111 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4688521..4689111 Escherichia coli UMN026 7157265 YP_002415138.1 CDS hupA NC_011751.1 4689298 4689570 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4689298..4689570 Escherichia coli UMN026 7159326 YP_002415139.1 CDS yjaH NC_011751.1 4689583 4690278 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4689583..4690278 Escherichia coli UMN026 7156732 YP_002415140.1 CDS zraP NC_011751.1 4690280 4690699 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98362023, 9694902; Product type pf : putative factor; zinc resistance protein complement(4690280..4690699) Escherichia coli UMN026 7159327 YP_002415141.1 CDS zraS NC_011751.1 4690937 4692313 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21140164, 89327164, 92255260, 11243806, 2666400; Product type r : regulator; sensor protein ZraS 4690937..4692313 Escherichia coli UMN026 7159692 YP_002415142.1 CDS zraR NC_011751.1 4692310 4693635 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4692310..4693635 Escherichia coli UMN026 7159694 YP_002415143.1 CDS purD NC_011751.1 4693632 4694921 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4693632..4694921) Escherichia coli UMN026 7159693 YP_002415144.1 CDS purH NC_011751.1 4694933 4696522 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4694933..4696522) Escherichia coli UMN026 7157575 YP_002415145.1 CDS yjaB NC_011751.1 4702436 4702879 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; hypothetical protein complement(4702436..4702879) Escherichia coli UMN026 7155564 YP_002415146.1 CDS metA NC_011751.1 4703036 4703965 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4703036..4703965 Escherichia coli UMN026 7159325 YP_002415147.1 CDS aceB NC_011751.1 4704234 4705835 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4704234..4705835 Escherichia coli UMN026 7157100 YP_002415148.1 CDS aceA NC_011751.1 4705865 4707169 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295197, 92112731, 92353108, 2836370, 3049537, 3060852, 3276689, 3290857, 3291954, 7826335; Product type e : enzyme; isocitrate lyase 4705865..4707169 Escherichia coli UMN026 7155676 YP_002415149.1 CDS aceK NC_011751.1 4707218 4708954 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4707218..4708954 Escherichia coli UMN026 7155675 YP_002415150.1 CDS arpA NC_011751.1 4708923 4711109 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1995429, 8014990; Product type r : regulator; regulator of acetyl CoA synthetase complement(4708923..4711109) Escherichia coli UMN026 7155679 YP_002415151.1 CDS iclR NC_011751.1 4711426 4712250 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR complement(4711426..4712250) Escherichia coli UMN026 7155795 YP_002415152.1 CDS metH NC_011751.1 4712450 4716133 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4712450..4716133 Escherichia coli UMN026 7156786 YP_002415153.1 CDS yjbB NC_011751.1 4716353 4717984 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4716353..4717984 Escherichia coli UMN026 7157106 YP_002415154.1 CDS pepE NC_011751.1 4718074 4718763 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4718074..4718763) Escherichia coli UMN026 7159329 YP_002415155.1 CDS ECUMN_4548 NC_011751.1 4719145 4720386 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7652212; Product type e : enzyme; L-sorbose 1-phosphate reductase complement(4719145..4720386) Escherichia coli UMN026 7157413 YP_002415156.1 CDS ECUMN_4549 NC_011751.1 4720426 4721280 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; sorbose permease IID component complement(4720426..4721280) Escherichia coli UMN026 7155466 YP_002415157.1 CDS ECUMN_4550 NC_011751.1 4721261 4722058 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; sorbose permease IIC component (PTS system) complement(4721261..4722058) Escherichia coli UMN026 7155467 YP_002415158.1 CDS ECUMN_4551 NC_011751.1 4722124 4722618 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234, 12662934; Product type t : transporter; sorbose-specific phosphotransferase enzyme IIB component (PTS system) complement(4722124..4722618) Escherichia coli UMN026 7155468 YP_002415159.1 CDS ECUMN_4552 NC_011751.1 4722618 4723025 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type t : transporter; sorbose-specific phosphotransferase enzyme IIA component (PTS system) complement(4722618..4723025) Escherichia coli UMN026 7155469 YP_002415160.1 CDS ECUMN_4553 NC_011751.1 4723035 4723841 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(4723035..4723841) Escherichia coli UMN026 7155470 YP_002415161.1 CDS ECUMN_4554 NC_011751.1 4723911 4724942 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type r : regulator; sorbitol/sorbose operon activator complement(4723911..4724942) Escherichia coli UMN026 7155471 YP_002415162.1 CDS yjbC NC_011751.1 4725206 4726078 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4725206..4726078 Escherichia coli UMN026 7155472 YP_002415163.1 CDS yjbD NC_011751.1 4726079 4726351 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4726079..4726351) Escherichia coli UMN026 7159330 YP_002415164.1 CDS lysC NC_011751.1 4726603 4727952 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(4726603..4727952) Escherichia coli UMN026 7159331 YP_002415165.1 CDS pgi NC_011751.1 4728477 4730126 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4728477..4730126 Escherichia coli UMN026 7157030 YP_002415166.1 CDS ECUMN_4559 NC_011751.1 4730575 4730823 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4730575..4730823) Escherichia coli UMN026 7157426 YP_002415167.1 CDS yjbF NC_011751.1 4730950 4731588 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4730950..4731588 Escherichia coli UMN026 7155473 YP_002415168.1 CDS yjbG NC_011751.1 4731585 4732322 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4731585..4732322 Escherichia coli UMN026 7159332 YP_002415169.1 CDS yjbH NC_011751.1 4732322 4734418 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative porin 4732322..4734418 Escherichia coli UMN026 7159333 YP_002415170.1 CDS ECUMN_4563 NC_011751.1 4734422 4734583 D Evidence 6 : Doubtful CDS; hypothetical protein 4734422..4734583 Escherichia coli UMN026 7159334 YP_002415171.1 CDS ECUMN_4564 NC_011751.1 4734465 4734743 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4734465..4734743) Escherichia coli UMN026 7155474 YP_002415172.1 CDS yjbA NC_011751.1 4734957 4735367 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10986267; Product type pm : putative membrane component; phosphate-starvation-inducible protein PsiE 4734957..4735367 Escherichia coli UMN026 7155475 YP_002415173.1 CDS malG NC_011751.1 4735461 4736351 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4735461..4736351) Escherichia coli UMN026 7159328 YP_002415174.1 CDS malF NC_011751.1 4736366 4737910 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4736366..4737910) Escherichia coli UMN026 7157043 YP_002415175.1 CDS malE NC_011751.1 4738064 4739254 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4738064..4739254) Escherichia coli UMN026 7157042 YP_002415176.1 CDS malK NC_011751.1 4739619 4740734 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4739619..4740734 Escherichia coli UMN026 7157041 YP_002415177.1 CDS lamB NC_011751.1 4740806 4742146 D porin involved in the transport of maltose and maltodextrins; maltoporin 4740806..4742146 Escherichia coli UMN026 7157045 YP_002415178.1 CDS malM NC_011751.1 4742296 4743216 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87141162, 2434655, 6086106; Product type pt : putative transporter; maltose regulon periplasmic protein 4742296..4743216 Escherichia coli UMN026 7156934 YP_002415179.1 CDS yjbI NC_011751.1 4743445 4745025 D in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 4743445..4745025 Escherichia coli UMN026 7157046 YP_002415180.1 CDS ubiC NC_011751.1 4745248 4745745 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4745248..4745745 Escherichia coli UMN026 7159335 YP_002415181.1 CDS ubiA NC_011751.1 4745758 4746630 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4745758..4746630 Escherichia coli UMN026 7158154 YP_002415182.1 CDS plsB NC_011751.1 4746785 4749208 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4746785..4749208) Escherichia coli UMN026 7158152 YP_002415183.1 CDS dgkA NC_011751.1 4749379 4749747 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10220339, 6257698, 86278195, 88111690, 2984194, 6309817, 8071224; Product type e : enzyme; diacylglycerol kinase 4749379..4749747 Escherichia coli UMN026 7157472 YP_002415184.1 CDS lexA NC_011751.1 4749857 4750465 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4749857..4750465 Escherichia coli UMN026 7156148 YP_002415185.1 CDS dinF NC_011751.1 4750484 4751863 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165788; Product type cp : cell process; DNA-damage-inducible SOS response protein 4750484..4751863 Escherichia coli UMN026 7156949 YP_002415186.1 CDS yjbJ NC_011751.1 4751979 4752188 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 4751979..4752188 Escherichia coli UMN026 7156168 YP_002415187.1 CDS zur NC_011751.1 4752230 4752745 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4752230..4752745) Escherichia coli UMN026 7159336 YP_002415188.1 CDS ECUMN_4582 NC_011751.1 4753063 4754025 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4753063..4754025 Escherichia coli UMN026 7159696 YP_002415189.1 CDS yjbN NC_011751.1 4754388 4755425 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA -dihydrouridine synthase A 4754388..4755425 Escherichia coli UMN026 7155476 YP_002415190.1 CDS pspG NC_011751.1 4755349 4755801 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4755349..4755801 Escherichia coli UMN026 7159337 YP_002415191.1 CDS qor NC_011751.1 4755967 4756950 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94089392, 7602590; Product type e : enzyme; quinone oxidoreductase, NADPH-dependent complement(4755967..4756950) Escherichia coli UMN026 7159338 YP_002415192.1 CDS dnaB NC_011751.1 4757033 4758448 D unwinds double stranded DNA; replicative DNA helicase 4757033..4758448 Escherichia coli UMN026 7157609 YP_002415193.1 CDS alr NC_011751.1 4758501 4759580 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4758501..4759580 Escherichia coli UMN026 7156184 YP_002415194.1 CDS tyrB NC_011751.1 4759833 4761026 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4759833..4761026 Escherichia coli UMN026 7155731 YP_002415195.1 CDS ECUMN_4590 NC_011751.1 4761248 4761790 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4761248..4761790) Escherichia coli UMN026 7158148 YP_002415196.1 CDS aphA NC_011751.1 4762152 4762865 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4762152..4762865 Escherichia coli UMN026 7155477 YP_002415197.1 CDS yjbQ NC_011751.1 4762976 4763392 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11972052; hypothetical protein 4762976..4763392 Escherichia coli UMN026 7155750 YP_002415198.1 CDS yjbR NC_011751.1 4763396 4763752 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4763396..4763752 Escherichia coli UMN026 7159339 YP_002415199.1 CDS uvrA NC_011751.1 4763787 4766609 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4763787..4766609) Escherichia coli UMN026 7159340 YP_002415200.1 CDS ssb NC_011751.1 4766864 4767400 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4766864..4767400 Escherichia coli UMN026 7158198 YP_002415201.1 CDS yjcB NC_011751.1 4767499 4767780 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4767499..4767780) Escherichia coli UMN026 7157982 YP_002415202.1 CDS yjcC NC_011751.1 4768200 4769792 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative signal transduction protein 4768200..4769792 Escherichia coli UMN026 7159341 YP_002415203.1 CDS soxS NC_011751.1 4769798 4770121 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4769798..4770121) Escherichia coli UMN026 7159342 YP_002415204.1 CDS soxR NC_011751.1 4770207 4770671 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91210176, 91360349, 94139656, 9564045, 10207625, 12670967, 1653416, 1708380, 7673113, 8065907, 8306957, 8631739, 8969171, 9019397, 9092651, 9204707; Product type r : regulator; DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 4770207..4770671 Escherichia coli UMN026 7157954 YP_002415205.1 CDS yjcD NC_011751.1 4771395 4772744 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease 4771395..4772744 Escherichia coli UMN026 7157857 YP_002415206.1 CDS yjcE NC_011751.1 4772895 4774544 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21557160, 11479290; Product type pt : putative transporter; putative cation/proton antiporter 4772895..4774544 Escherichia coli UMN026 7159343 YP_002415207.1 CDS yjcF NC_011751.1 4774698 4775990 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4774698..4775990) Escherichia coli UMN026 7159344 YP_002415208.1 CDS actP NC_011751.1 4776168 4777817 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4776168..4777817) Escherichia coli UMN026 7159345 YP_002415209.1 CDS yjcH NC_011751.1 4777814 4778128 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14563880; Product type pm : putative membrane component; hypothetical protein complement(4777814..4778128) Escherichia coli UMN026 7155694 YP_002415210.1 CDS acs NC_011751.1 4778601 4780559 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4778601..4780559) Escherichia coli UMN026 7159346 YP_002415211.1 CDS nrfA NC_011751.1 4780951 4782387 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4780951..4782387 Escherichia coli UMN026 7155693 YP_002415212.1 CDS nrfB NC_011751.1 4782432 4782998 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4782432..4782998 Escherichia coli UMN026 7157307 YP_002415213.1 CDS nrfC NC_011751.1 4782995 4783666 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94335626, 8057835; Product type c : carrier; formate-dependent nitrite reductase, 4Fe4S subunit 4782995..4783666 Escherichia coli UMN026 7157308 YP_002415214.1 CDS nrfD NC_011751.1 4783663 4784619 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 8057835; Product type e : enzyme; formate-dependent nitrite reductase, membrane subunit 4783663..4784619 Escherichia coli UMN026 7157309 YP_002415215.1 CDS nrfE NC_011751.1 4784699 4786357 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4784699..4786357 Escherichia coli UMN026 7157310 YP_002415216.1 CDS nrfF NC_011751.1 4786350 4786733 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor; formate-dependent nitrite reductase complex subunit NrfF 4786350..4786733 Escherichia coli UMN026 7157311 YP_002415217.1 CDS nrfG NC_011751.1 4786730 4787326 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor; formate-dependent nitrite reductase complex subunit NrfG 4786730..4787326 Escherichia coli UMN026 7157312 YP_002415218.1 CDS gltP NC_011751.1 4787668 4788981 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4787668..4788981 Escherichia coli UMN026 7157313 YP_002415219.1 CDS yjcO NC_011751.1 4789286 4789975 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4789286..4789975) Escherichia coli UMN026 7156580 YP_002415220.1 CDS fdhF NC_011751.1 4790069 4792216 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-H, selenopolypeptide subunit complement(4790069..4792216) Escherichia coli UMN026 7159347 YP_002415221.1 CDS yjcP NC_011751.1 4792414 4793880 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP complement(4792414..4793880) Escherichia coli UMN026 7156315 YP_002415222.1 CDS yjcQ NC_011751.1 4793877 4795928 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4793877..4795928) Escherichia coli UMN026 7159348 YP_002415223.1 CDS yjcR NC_011751.1 4795928 4796959 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4795928..4796959) Escherichia coli UMN026 7159349 YP_002415224.1 CDS yjcS NC_011751.1 4797462 4799447 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1587481; Product type pe : putative enzyme; putative alkyl sulfatase complement(4797462..4799447) Escherichia coli UMN026 7159350 YP_002415225.1 CDS ECUMN_4621 NC_011751.1 4799700 4800017 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ribose-5-phosphate isomerase B 4799700..4800017 Escherichia coli UMN026 7159351 YP_002415226.1 CDS yjdP NC_011751.1 4800086 4800415 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4800086..4800415 Escherichia coli UMN026 7155478 YP_002415227.1 CDS phnP NC_011751.1 4800450 4801208 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4800450..4801208) Escherichia coli UMN026 7159362 YP_002415228.1 CDS phnO NC_011751.1 4801210 4801644 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4801210..4801644) Escherichia coli UMN026 7157454 YP_002415229.1 CDS phnN NC_011751.1 4801631 4802188 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700258, 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; ribose 1,5-bisphosphokinase complement(4801631..4802188) Escherichia coli UMN026 7157453 YP_002415230.1 CDS phnM NC_011751.1 4802188 4803324 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit complement(4802188..4803324) Escherichia coli UMN026 7157452 YP_002415231.1 CDS phnL NC_011751.1 4803321 4804001 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit complement(4803321..4804001) Escherichia coli UMN026 7157451 YP_002415232.1 CDS phnK NC_011751.1 4804112 4804870 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; phosphonate C-P lyase system protein PhnK complement(4804112..4804870) Escherichia coli UMN026 7157450 YP_002415233.1 CDS phnJ NC_011751.1 4804867 4805712 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit complement(4804867..4805712) Escherichia coli UMN026 7157449 YP_002415234.1 CDS phnI NC_011751.1 4805705 4806769 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit complement(4805705..4806769) Escherichia coli UMN026 7157448 YP_002415235.1 CDS phnH NC_011751.1 4806769 4807353 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit complement(4806769..4807353) Escherichia coli UMN026 7157447 YP_002415236.1 CDS phnG NC_011751.1 4807350 4807802 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit complement(4807350..4807802) Escherichia coli UMN026 7157446 YP_002415237.1 CDS phnF NC_011751.1 4807803 4808528 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4807803..4808528) Escherichia coli UMN026 7157445 YP_002415238.1 CDS phnE NC_011751.1 4808549 4809328 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; phosphonates transport system, permease protein complement(4808549..4809328) Escherichia coli UMN026 7157444 YP_002415239.1 CDS phnD NC_011751.1 4809389 4810405 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter; phosphonate/organophosphate ester ABC transporter periplasmic binding protein complement(4809389..4810405) Escherichia coli UMN026 7157443 YP_002415240.1 CDS phnC NC_011751.1 4810430 4811218 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter; phosphonate/organophosphate ester transporter subunit complement(4810430..4811218) Escherichia coli UMN026 7157442 YP_002415241.1 CDS phnB NC_011751.1 4811351 4811794 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230; hypothetical protein complement(4811351..4811794) Escherichia coli UMN026 7157441 YP_002415242.1 CDS phnA NC_011751.1 4811954 4812289 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230; hypothetical protein complement(4811954..4812289) Escherichia coli UMN026 7157440 YP_002415243.1 CDS yjdA NC_011751.1 4812691 4814919 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4812691..4814919 Escherichia coli UMN026 7157439 YP_002415244.1 CDS yjcZ NC_011751.1 4814916 4815794 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4814916..4815794 Escherichia coli UMN026 7159353 YP_002415245.1 CDS proP NC_011751.1 4816058 4817560 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10049386, 12525168, 92165733, 93132799, 9871325, 99376621, 8421314; Product type t : transporter; proline/glycine betaine transporter 4816058..4817560 Escherichia coli UMN026 7159352 YP_002415246.1 CDS basS NC_011751.1 4817737 4818828 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; sensor protein BasS/PmrB complement(4817737..4818828) Escherichia coli UMN026 7157533 YP_002415247.1 CDS basR NC_011751.1 4818838 4819506 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4818838..4819506) Escherichia coli UMN026 7155853 YP_002415248.1 CDS eptA NC_011751.1 4819503 4821146 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein complement(4819503..4821146) Escherichia coli UMN026 7155852 YP_002415249.1 CDS adiC NC_011751.1 4821250 4822587 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12867448; Product type t : transporter; arginine:agmatin antiporter complement(4821250..4822587) Escherichia coli UMN026 7156265 YP_002415250.1 CDS adiY NC_011751.1 4822724 4823485 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : c; Product type r : regulator; DNA-binding transcriptional activator complement(4822724..4823485) Escherichia coli UMN026 7155701 YP_002415251.1 CDS adiA NC_011751.1 4823821 4826091 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93186686, 2830169, 4204273, 8383109; Product type e : enzyme; biodegradative arginine decarboxylase complement(4823821..4826091) Escherichia coli UMN026 7155702 YP_002415252.1 CDS melR NC_011751.1 4826287 4827195 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90060832, 9108148, 1445207, 2684786, 2830169; Product type r : regulator; DNA-binding transcriptional regulator MelR complement(4826287..4827195) Escherichia coli UMN026 7155700 YP_002415253.1 CDS melA NC_011751.1 4827478 4828833 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87174747, 88162811, 90248411, 2831880, 3031590, 6329200; Product type e : enzyme; alpha-galactosidase 4827478..4828833 Escherichia coli UMN026 7157092 YP_002415254.1 CDS melB NC_011751.1 4828948 4830357 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14757226, 90241878, 92297631, 93155159, 1730719, 1872836, 6323466, 8672452; Product type t : transporter; melibiose:sodium symporter 4828948..4830357 Escherichia coli UMN026 7157090 YP_002415255.1 CDS yjdF NC_011751.1 4830496 4831125 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4830496..4831125) Escherichia coli UMN026 7157091 YP_002415256.1 CDS fumB NC_011751.1 4831248 4832894 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86142617, 88193096, 89255123, 2656658; Product type e : enzyme; anaerobic class I fumarate hydratase complement(4831248..4832894) Escherichia coli UMN026 7159356 YP_002415257.1 CDS dcuB NC_011751.1 4832972 4834312 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4832972..4834312) Escherichia coli UMN026 7156477 YP_002415258.1 CDS dcuR NC_011751.1 4834883 4835602 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4834883..4835602) Escherichia coli UMN026 7156119 YP_002415259.1 CDS dcuS NC_011751.1 4835599 4837230 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4835599..4837230) Escherichia coli UMN026 7156122 YP_002415260.1 CDS yjdI NC_011751.1 4837411 4837641 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4837411..4837641 Escherichia coli UMN026 7156123 YP_002415261.1 CDS yjdJ NC_011751.1 4837653 4837925 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 4837653..4837925 Escherichia coli UMN026 7159357 YP_002415262.1 CDS yjdK NC_011751.1 4838154 4838450 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4838154..4838450 Escherichia coli UMN026 7159358 YP_002415263.1 CDS yjdO NC_011751.1 4838478 4838651 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4838478..4838651 Escherichia coli UMN026 7159359 YP_002415264.1 CDS lysU NC_011751.1 4838769 4840286 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4838769..4840286) Escherichia coli UMN026 7159361 YP_002415265.1 CDS yjdL NC_011751.1 4840523 4841980 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter complement(4840523..4841980) Escherichia coli UMN026 7157034 YP_002415266.1 CDS cadA NC_011751.1 4842039 4844186 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105022, 92210511, 1370290, 1556085, 4204273; Product type e : enzyme; lysine decarboxylase 1 complement(4842039..4844186) Escherichia coli UMN026 7159360 YP_002415267.1 CDS cadB NC_011751.1 4844266 4845600 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4844266..4845600) Escherichia coli UMN026 7155907 YP_002415268.1 CDS cadC NC_011751.1 4845966 4847504 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(4845966..4847504) Escherichia coli UMN026 7155908 YP_002415269.1 CDS ECUMN_4668 NC_011751.1 4847740 4848009 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4847740..4848009 Escherichia coli UMN026 7155909 YP_002415270.1 CDS dipZ NC_011751.1 4848905 4850602 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4848905..4850602) Escherichia coli UMN026 7159355 YP_002415271.1 CDS cutA NC_011751.1 4850578 4850916 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4850578..4850916) Escherichia coli UMN026 7156171 YP_002415272.1 CDS dcuA NC_011751.1 4851031 4852332 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4851031..4852332) Escherichia coli UMN026 7156056 YP_002415273.1 CDS aspA NC_011751.1 4852450 4853886 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4852450..4853886) Escherichia coli UMN026 7156118 YP_002415274.1 CDS fxsA NC_011751.1 4854223 4854699 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 4854223..4854699 Escherichia coli UMN026 7155817 YP_002415275.1 CDS yjeH NC_011751.1 4854715 4855971 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH complement(4854715..4855971) Escherichia coli UMN026 7156481 YP_002415276.1 CDS groES NC_011751.1 4856247 4856540 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4856247..4856540 Escherichia coli UMN026 7159365 YP_002415277.1 CDS groEL NC_011751.1 4856584 4858230 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4856584..4858230 Escherichia coli UMN026 7156612 YP_002415278.1 CDS yjeI NC_011751.1 4858368 4858721 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4858368..4858721 Escherichia coli UMN026 7156611 YP_002415279.1 CDS yjeJ NC_011751.1 4858771 4859640 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4858771..4859640) Escherichia coli UMN026 7159366 YP_002415280.1 CDS yjeK NC_011751.1 4859875 4860903 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019591, 10629195; Product type pe : putative enzyme; putative lysine aminomutase complement(4859875..4860903) Escherichia coli UMN026 7159367 YP_002415281.1 CDS efp NC_011751.1 4860945 4861511 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4860945..4861511 Escherichia coli UMN026 7159368 YP_002415282.1 CDS ECUMN_4683 NC_011751.1 4861783 4862034 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4861783..4862034) Escherichia coli UMN026 7156231 YP_002415283.1 CDS sugE NC_011751.1 4862120 4862437 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4862120..4862437 Escherichia coli UMN026 7155480 YP_002415284.1 CDS blc NC_011751.1 4862434 4862967 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4862434..4862967) Escherichia coli UMN026 7158009 YP_002415285.1 CDS ampC NC_011751.1 4863056 4864189 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212899, 97464439, 99421326, 10595535, 6795623, 7041115, 9819201; Product type e : enzyme; beta-lactamase complement(4863056..4864189) Escherichia coli UMN026 7155887 YP_002415286.1 CDS frdD NC_011751.1 4864252 4864611 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4864252..4864611) Escherichia coli UMN026 7155737 YP_002415287.1 CDS frdC NC_011751.1 4864622 4865017 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4864622..4865017) Escherichia coli UMN026 7156437 YP_002415288.1 CDS frdB NC_011751.1 4865028 4865762 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4865028..4865762) Escherichia coli UMN026 7156436 YP_002415289.1 CDS frdA NC_011751.1 4865755 4867563 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4865755..4867563) Escherichia coli UMN026 7156435 YP_002415290.1 CDS poxA NC_011751.1 4867888 4868865 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4867888..4868865 Escherichia coli UMN026 7156434 YP_002415291.1 CDS yjeM NC_011751.1 4869084 4870586 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4869084..4870586 Escherichia coli UMN026 7157495 YP_002415292.1 CDS yjeP NC_011751.1 4870737 4874060 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein complement(4870737..4874060) Escherichia coli UMN026 7159369 YP_002415293.1 CDS psd NC_011751.1 4874082 4875050 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4874082..4875050) Escherichia coli UMN026 7159370 YP_002415294.1 CDS rsgA NC_011751.1 4875147 4876199 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4875147..4876199) Escherichia coli UMN026 7157548 YP_002415295.1 CDS orn NC_011751.1 4876294 4876839 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4876294..4876839 Escherichia coli UMN026 7157796 YP_002415296.1 CDS yjeS NC_011751.1 4877739 4878878 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Fe-S electron transport protein complement(4877739..4878878) Escherichia coli UMN026 7155610 YP_002415297.1 CDS yjeF NC_011751.1 4878877 4880424 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 4878877..4880424 Escherichia coli UMN026 7159371 YP_002415298.1 CDS yjeE NC_011751.1 4880396 4880857 D possibly involved in cell wall synthesis; putative ATPase 4880396..4880857 Escherichia coli UMN026 7159364 YP_002415299.1 CDS amiB NC_011751.1 4880876 4882213 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 87242501, 1594459, 7511774; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase II 4880876..4882213 Escherichia coli UMN026 7159363 YP_002415300.1 CDS mutL NC_011751.1 4882223 4884070 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4882223..4884070 Escherichia coli UMN026 7155734 YP_002415301.1 CDS miaA NC_011751.1 4884063 4885013 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4884063..4885013 Escherichia coli UMN026 7157212 YP_002415302.1 CDS hfq NC_011751.1 4885099 4885407 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4885099..4885407 Escherichia coli UMN026 7157128 YP_002415303.1 CDS hflX NC_011751.1 4885484 4886764 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 4885484..4886764 Escherichia coli UMN026 7156667 YP_002415304.1 CDS hflK NC_011751.1 4886850 4888109 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4886850..4888109 Escherichia coli UMN026 7156666 YP_002415305.1 CDS hflC NC_011751.1 4888112 4889116 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4888112..4889116 Escherichia coli UMN026 7156665 YP_002415306.1 CDS yjeT NC_011751.1 4889198 4889395 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4889198..4889395 Escherichia coli UMN026 7156663 YP_002415307.1 CDS purA NC_011751.1 4889499 4890797 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4889499..4890797 Escherichia coli UMN026 7159372 YP_002415308.1 CDS nsrR NC_011751.1 4891002 4891427 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4891002..4891427 Escherichia coli UMN026 7157572 YP_002415309.1 CDS rnr NC_011751.1 4891466 4893907 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4891466..4893907 Escherichia coli UMN026 7157314 YP_002415310.1 CDS rlmB NC_011751.1 4893998 4894729 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4893998..4894729 Escherichia coli UMN026 7157718 YP_002415311.1 CDS yjfI NC_011751.1 4894856 4895257 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4894856..4895257 Escherichia coli UMN026 7157696 YP_002415312.1 CDS yjfJ NC_011751.1 4895276 4895974 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator effector protein 4895276..4895974 Escherichia coli UMN026 7159375 YP_002415313.1 CDS yjfK NC_011751.1 4896025 4896684 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4896025..4896684 Escherichia coli UMN026 7159376 YP_002415314.1 CDS yjfL NC_011751.1 4896702 4897100 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4896702..4897100 Escherichia coli UMN026 7159377 YP_002415315.1 CDS yjfM NC_011751.1 4897110 4897748 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4897110..4897748 Escherichia coli UMN026 7159378 YP_002415316.1 CDS yjfC NC_011751.1 4897751 4898914 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative synthetase/amidase 4897751..4898914 Escherichia coli UMN026 7159379 YP_002415317.1 CDS aidB NC_011751.1 4898998 4900623 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4898998..4900623 Escherichia coli UMN026 7159373 YP_002415318.1 CDS yjfN NC_011751.1 4900740 4901015 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4900740..4901015) Escherichia coli UMN026 7155719 YP_002415319.1 CDS yjfO NC_011751.1 4901164 4901493 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A complement(4901164..4901493) Escherichia coli UMN026 7159380 YP_002415320.1 CDS yjfP NC_011751.1 4901675 4902424 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4901675..4902424 Escherichia coli UMN026 7159381 YP_002415321.1 CDS ulaR NC_011751.1 4902421 4903176 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4902421..4903176) Escherichia coli UMN026 7159382 YP_002415322.1 CDS ulaG NC_011751.1 4903284 4904348 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12644495, 15808744; Product type pe : putative enzyme; putative L-ascorbate 6-phosphate lactonase complement(4903284..4904348) Escherichia coli UMN026 7158185 YP_002415323.1 CDS ulaA NC_011751.1 4904703 4906100 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4904703..4906100 Escherichia coli UMN026 7158184 YP_002415324.1 CDS ulaB NC_011751.1 4906116 4906421 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4906116..4906421 Escherichia coli UMN026 7158178 YP_002415325.1 CDS ulaC NC_011751.1 4906431 4906895 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4906431..4906895 Escherichia coli UMN026 7158179 YP_002415326.1 CDS ulaD NC_011751.1 4906909 4907559 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4906909..4907559 Escherichia coli UMN026 7158180 YP_002415327.1 CDS ulaE NC_011751.1 4907569 4908423 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4907569..4908423 Escherichia coli UMN026 7158181 YP_002415328.1 CDS sgaE NC_011751.1 4908423 4909109 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4908423..4909109 Escherichia coli UMN026 7158182 YP_002415329.1 CDS yjfY NC_011751.1 4909239 4909514 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4909239..4909514) Escherichia coli UMN026 7158183 YP_002415330.1 CDS rpsF NC_011751.1 4909841 4910236 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4909841..4910236 Escherichia coli UMN026 7159383 YP_002415331.1 CDS priB NC_011751.1 4910243 4910557 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4910243..4910557 Escherichia coli UMN026 7157772 YP_002415332.1 CDS rpsR NC_011751.1 4910562 4910789 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4910562..4910789 Escherichia coli UMN026 7157523 YP_002415333.1 CDS rplI NC_011751.1 4910831 4911280 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4910831..4911280 Escherichia coli UMN026 7157784 YP_002415334.1 CDS yjfZ NC_011751.1 4911351 4912145 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4911351..4912145) Escherichia coli UMN026 7157731 YP_002415335.1 CDS ECUMN_4739 NC_011751.1 4913086 4913232 D Evidence 6 : Doubtful CDS; hypothetical protein 4913086..4913232 Escherichia coli UMN026 7159666 YP_002415336.1 CDS ydcM NC_011751.1 4913210 4914406 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase 4913210..4914406 Escherichia coli UMN026 7155481 YP_002415337.1 CDS ytfB NC_011751.1 4914553 4915191 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8559074; Product type ps : putative structure; putative cell envelope opacity-associated protein complement(4914553..4915191) Escherichia coli UMN026 7158611 YP_002415338.1 CDS fklB NC_011751.1 4915409 4916029 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4915409..4916029 Escherichia coli UMN026 7159667 YP_002415339.1 CDS cycA NC_011751.1 4916338 4917741 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4916338..4917741 Escherichia coli UMN026 7156372 YP_002415340.1 CDS ECUMN_4744 NC_011751.1 4917875 4919038 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4917875..4919038 Escherichia coli UMN026 7156064 YP_002415341.1 CDS ECUMN_4745 NC_011751.1 4919072 4920556 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4919072..4920556 Escherichia coli UMN026 7155482 YP_002415342.1 CDS ytfE NC_011751.1 4920601 4921263 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4920601..4921263) Escherichia coli UMN026 7155483 YP_002415343.1 CDS ytfF NC_011751.1 4921371 4922345 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4921371..4922345) Escherichia coli UMN026 7159668 YP_002415344.1 CDS ytfG NC_011751.1 4922445 4923305 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14747727; Product type e : enzyme; NAD(P)H:quinone oxidoreductase complement(4922445..4923305) Escherichia coli UMN026 7159669 YP_002415345.1 CDS ytfH NC_011751.1 4923393 4923773 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20088838; Product type pr : putative regulator; putative transcriptional regulator 4923393..4923773 Escherichia coli UMN026 7159670 YP_002415346.1 CDS cpdB NC_011751.1 4923902 4925845 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4923902..4925845) Escherichia coli UMN026 7159671 YP_002415347.1 CDS cysQ NC_011751.1 4926035 4926775 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4926035..4926775 Escherichia coli UMN026 7156001 YP_002415348.1 CDS ytfJ NC_011751.1 4926765 4927322 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pr : putative regulator; putative transcriptional regulator complement(4926765..4927322) Escherichia coli UMN026 7156091 YP_002415349.1 CDS ytfK NC_011751.1 4927647 4927853 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4927647..4927853 Escherichia coli UMN026 7159672 YP_002415350.1 CDS ytfL NC_011751.1 4927914 4929257 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(4927914..4929257) Escherichia coli UMN026 7159673 YP_002415351.1 CDS msrA NC_011751.1 4929580 4930218 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4929580..4930218) Escherichia coli UMN026 7159674 YP_002415352.1 CDS ytfM NC_011751.1 4930424 4932157 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4930424..4932157 Escherichia coli UMN026 7157187 YP_002415353.1 CDS ytfN NC_011751.1 4932154 4935933 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4932154..4935933 Escherichia coli UMN026 7159675 YP_002415354.1 CDS ytfP NC_011751.1 4935936 4936277 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4935936..4936277 Escherichia coli UMN026 7159676 YP_002415355.1 CDS ppa NC_011751.1 4936657 4937187 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4936657..4937187) Escherichia coli UMN026 7159677 YP_002415356.1 CDS ytfQ NC_011751.1 4937497 4938453 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter; putative sugar ABC transporter periplasmic-binding protein 4937497..4938453 Escherichia coli UMN026 7157497 YP_002415357.1 CDS ytfR NC_011751.1 4938763 4940265 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter ATP-binding protein 4938763..4940265 Escherichia coli UMN026 7159678 YP_002415358.1 CDS ytfT NC_011751.1 4940279 4941301 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter membrane protein 4940279..4941301 Escherichia coli UMN026 7159679 YP_002415359.1 CDS yjfF NC_011751.1 4941288 4942283 D membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease protein YjfF 4941288..4942283 Escherichia coli UMN026 7159680 YP_002415360.1 CDS fbp NC_011751.1 4942316 4943314 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4942316..4943314) Escherichia coli UMN026 7159374 YP_002415361.1 CDS mpl NC_011751.1 4943490 4944863 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96404780, 2843822, 7984428, 8808921; Product type e : enzyme; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4943490..4944863 Escherichia coli UMN026 7156311 YP_002415362.1 CDS yjgA NC_011751.1 4945014 4945565 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4945014..4945565) Escherichia coli UMN026 7157167 YP_002415363.1 CDS pmbA NC_011751.1 4945659 4947011 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4945659..4947011 Escherichia coli UMN026 7159385 YP_002415364.1 CDS cybC NC_011751.1 4947194 4947580 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1761034, 8499452, 10393541; Product type c : carrier; soluble cytochrome b562 4947194..4947580 Escherichia coli UMN026 7157476 YP_002415365.1 CDS nrdG NC_011751.1 4947625 4948089 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4947625..4948089) Escherichia coli UMN026 7156063 YP_002415366.1 CDS nrdD NC_011751.1 4948247 4950385 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4948247..4950385) Escherichia coli UMN026 7157303 YP_002415367.1 CDS treC NC_011751.1 4950779 4952434 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264345, 93302496, 8083158, 8421692; Product type e : enzyme; trehalose-6-phosphate hydrolase complement(4950779..4952434) Escherichia coli UMN026 7157300 YP_002415368.1 CDS treB NC_011751.1 4952484 4953905 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC complement(4952484..4953905) Escherichia coli UMN026 7158104 YP_002415369.1 CDS treR NC_011751.1 4954024 4954971 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4954024..4954971) Escherichia coli UMN026 7158103 YP_002415370.1 CDS mgtA NC_011751.1 4955350 4958046 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4955350..4958046 Escherichia coli UMN026 7158106 YP_002415371.1 CDS yjgF NC_011751.1 4958252 4958638 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12515541, 10493123, 10595546, 9298646; Product type pe : putative enzyme; ketoacid-binding protein complement(4958252..4958638) Escherichia coli UMN026 7157119 YP_002415372.1 CDS pyrI NC_011751.1 4958711 4959172 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit complement(4958711..4959172) Escherichia coli UMN026 7159388 YP_002415373.1 CDS pyrB NC_011751.1 4959185 4960120 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(4959185..4960120) Escherichia coli UMN026 7157604 YP_002415374.1 CDS pyrL NC_011751.1 4960124 4960258 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; pyrBI operon leader peptide complement(4960124..4960258) Escherichia coli UMN026 7157597 YP_002415375.1 CDS yjgH NC_011751.1 4960539 4960934 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mRNA endoribonuclease complement(4960539..4960934) Escherichia coli UMN026 7157605 YP_002415376.1 CDS yjgI NC_011751.1 4961065 4961778 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; oxidoreductase complement(4961065..4961778) Escherichia coli UMN026 7159389 YP_002415377.1 CDS yjgJ NC_011751.1 4961849 4962442 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4961849..4962442 Escherichia coli UMN026 7159390 YP_002415378.1 CDS yjgK NC_011751.1 4962587 4963039 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11115104; hypothetical protein 4962587..4963039 Escherichia coli UMN026 7159391 YP_002415379.1 CDS argI NC_011751.1 4964822 4965826 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I complement(4964822..4965826) Escherichia coli UMN026 7159395 YP_002415380.1 CDS yjgD NC_011751.1 4965988 4966404 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4965988..4966404 Escherichia coli UMN026 7155775 YP_002415381.1 CDS yjgM NC_011751.1 4966450 4966953 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase complement(4966450..4966953) Escherichia coli UMN026 7159387 YP_002415382.1 CDS yjgN NC_011751.1 4967146 4968342 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4967146..4968342 Escherichia coli UMN026 7159396 YP_002415383.1 CDS valS NC_011751.1 4968398 4971253 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4968398..4971253) Escherichia coli UMN026 7159397 YP_002415384.1 CDS holC NC_011751.1 4971253 4971696 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4971253..4971696) Escherichia coli UMN026 7158210 YP_002415385.1 CDS pepA NC_011751.1 4971952 4973463 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4971952..4973463) Escherichia coli UMN026 7156698 YP_002415386.1 CDS yjgP NC_011751.1 4973730 4974830 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4973730..4974830 Escherichia coli UMN026 7157410 YP_002415387.1 CDS yjgQ NC_011751.1 4974830 4975912 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4974830..4975912 Escherichia coli UMN026 7159398 YP_002415388.1 CDS yjgR NC_011751.1 4976073 4977575 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATPase complement(4976073..4977575) Escherichia coli UMN026 7159399 YP_002415389.1 CDS idnR NC_011751.1 4977653 4978651 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9119199, 98324983, 9658018; Product type r : regulator; DNA-binding transcriptional repressor complement(4977653..4978651) Escherichia coli UMN026 7159400 YP_002415390.1 CDS idnT NC_011751.1 4978718 4980037 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9119199, 93139975, 98324983, 9658018; Product type t : transporter; L-idonate and D-gluconate transporter complement(4978718..4980037) Escherichia coli UMN026 7156791 YP_002415391.1 CDS idnO NC_011751.1 4980099 4980863 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(4980099..4980863) Escherichia coli UMN026 7156792 YP_002415392.1 CDS idnD NC_011751.1 4980887 4981918 R NAD-binding; L-idonate 5-dehydrogenase complement(4980887..4981918) Escherichia coli UMN026 7156790 YP_002415393.1 CDS idnK NC_011751.1 4982135 4982698 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87310381, 93139975, 98324983, 9658018, 14832279; Product type e : enzyme; D-gluconate kinase 4982135..4982698 Escherichia coli UMN026 7156788 YP_002415394.1 CDS yjgB NC_011751.1 4982702 4983721 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12147722; Product type pe : putative enzyme; putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding complement(4982702..4983721) Escherichia coli UMN026 7156789 YP_002415395.1 CDS ECUMN_4802 NC_011751.1 4983796 4984023 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4983796..4984023) Escherichia coli UMN026 7159386 YP_002415396.1 CDS intB NC_011751.1 4984262 4985452 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative integrase; KpLE2 phage-like element 4984262..4985452 Escherichia coli UMN026 7155611 YP_002415397.1 CDS insB NC_011751.1 4985626 4986129 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage complement(4985626..4986129) Escherichia coli UMN026 7156843 YP_002415398.1 CDS insA NC_011751.1 4986048 4986323 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA complement(4986048..4986323) Escherichia coli UMN026 7156820 YP_002415399.1 CDS cat NC_011751.1 4986477 4987136 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 390404, 390403, 7353655; Product type e : enzyme; chloramphenicol acetyltransferase complement(4986477..4987136) Escherichia coli UMN026 7156815 YP_002415400.1 CDS ECUMN_4807 NC_011751.1 4987190 4987381 D Evidence 6 : Doubtful CDS; hypothetical protein 4987190..4987381 Escherichia coli UMN026 7155920 YP_002415401.1 CDS insA NC_011751.1 4987415 4987690 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 4987415..4987690 Escherichia coli UMN026 7155485 YP_002415402.1 CDS insB NC_011751.1 4987609 4988097 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage 4987609..4988097 Escherichia coli UMN026 7156816 YP_002415403.1 CDS ECUMN_4810 NC_011751.1 4988126 4988848 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 4988126..4988848 Escherichia coli UMN026 7156821 YP_002415404.1 CDS ECUMN_4811 NC_011751.1 4988794 4991865 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase TnpA, Tn21 complement(4988794..4991865) Escherichia coli UMN026 7155486 YP_002415405.1 CDS ECUMN_4812 NC_011751.1 4991868 4992428 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; resolvase transposon Tn21 complement(4991868..4992428) Escherichia coli UMN026 7155487 YP_002415406.1 CDS ECUMN_4813 NC_011751.1 4992554 4993168 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; protein TnpM, transposon Tn21 complement(4992554..4993168) Escherichia coli UMN026 7155488 YP_002415407.1 CDS ECUMN_4814 NC_011751.1 4993107 4994120 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Integrase/recombinase (E2 protein) complement(4993107..4994120) Escherichia coli UMN026 7155489 YP_002415408.1 CDS aadA NC_011751.1 4994882 4995670 D streptomycin 3'-adenyltransferase; aminoglycoside resistance protein 4994882..4995670 Escherichia coli UMN026 7156160 YP_002415409.1 CDS ECUMN_4817 NC_011751.1 4995885 4996607 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 4995885..4996607 Escherichia coli UMN026 7155655 YP_002415410.1 CDS ECUMN_4818 NC_011751.1 4996740 4997945 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative chromate ion transporter complement(4996740..4997945) Escherichia coli UMN026 7155491 YP_002415411.1 CDS sulI NC_011751.1 4998432 4999271 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2662140, 11544236; Product type e : enzyme; dihydropteroate synthase complement(4998432..4999271) Escherichia coli UMN026 7155493 YP_002415412.1 CDS ebr NC_011751.1 4999265 4999612 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3054482, 1314803, 8195081; Product type pm : putative membrane component; putative ethidium bromide resistance protein complement(4999265..4999612) Escherichia coli UMN026 7158012 YP_002415413.1 CDS ECUMN_4822 NC_011751.1 4999709 5000431 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 complement(4999709..5000431) Escherichia coli UMN026 7156222 YP_002415414.1 CDS ECUMN_4824 NC_011751.1 5000932 5001288 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5000932..5001288) Escherichia coli UMN026 7155495 YP_002415415.1 CDS mphR NC_011751.1 5001234 5001818 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8619599, 10960087; Product type r : regulator; regulator of macrolide 2'-phosphotransferase I complement(5001234..5001818) Escherichia coli UMN026 7155496 YP_002415416.1 CDS ECUMN_4826 NC_011751.1 5001818 5003056 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5001818..5003056) Escherichia coli UMN026 7157166 YP_002415417.1 CDS mphA NC_011751.1 5003053 5003958 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8619599, 10960087; Product type e : enzyme; macrolide 2'-phosphotransferase I complement(5003053..5003958) Escherichia coli UMN026 7155497 YP_002415418.1 CDS ECUMN_4828 NC_011751.1 5004080 5004802 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 complement(5004080..5004802) Escherichia coli UMN026 7157165 YP_002415419.1 CDS bla NC_011751.1 5005369 5006229 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 358200, 3019092, 15769331; Product type e : enzyme; beta-lactamase 5005369..5006229 Escherichia coli UMN026 7155499 YP_002415420.1 CDS insB NC_011751.1 5006786 5007289 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage complement(5006786..5007289) Escherichia coli UMN026 7155500 YP_002415421.1 CDS insA NC_011751.1 5007208 5007483 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA complement(5007208..5007483) Escherichia coli UMN026 7156822 YP_002415422.1 CDS ECUMN_4836 NC_011751.1 5008544 5009011 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5008544..5009011) Escherichia coli UMN026 7155502 YP_002415423.1 CDS ECUMN_4837 NC_011751.1 5009146 5009340 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5009146..5009340 Escherichia coli UMN026 7155503 YP_002415424.1 CDS ECUMN_4838 NC_011751.1 5009394 5009615 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5009394..5009615 Escherichia coli UMN026 7155504 YP_002415425.1 CDS ECUMN_4839 NC_011751.1 5010044 5010187 D Evidence 6 : Doubtful CDS; hypothetical protein 5010044..5010187 Escherichia coli UMN026 7155505 YP_002415426.1 CDS insG NC_011751.1 5010215 5011561 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative IS4 transposase; KpLE2 phage-like element complement(5010215..5011561) Escherichia coli UMN026 7155506 YP_002415427.1 CDS yjhB NC_011751.1 5012170 5013387 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sialic acid transporter 5012170..5013387 Escherichia coli UMN026 7156828 YP_002415428.1 CDS yjhC NC_011751.1 5013399 5014517 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase; KpLE2 phage-like element 5013399..5014517 Escherichia coli UMN026 7159403 YP_002415429.1 CDS ECUMN_4843 NC_011751.1 5014738 5015133 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(5014738..5015133) Escherichia coli UMN026 7159404 YP_002415430.1 CDS ECUMN_4844 NC_011751.1 5014973 5015221 D hypothetical protein 5014973..5015221 Escherichia coli UMN026 7155507 YP_002415431.1 CDS ECUMN_4846 NC_011751.1 5015637 5016476 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS911 5015637..5016476 Escherichia coli UMN026 7155509 YP_002415432.1 CDS ECUMN_4848 NC_011751.1 5016887 5018890 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702297; Product type t : transporter; betaine-carnitine-choline transporter family member BetU complement(5016887..5018890) Escherichia coli UMN026 7155510 YP_002415433.1 CDS ECUMN_4849 NC_011751.1 5019038 5019856 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS600 complement(5019038..5019856) Escherichia coli UMN026 7155511 YP_002415434.1 CDS insI NC_011751.1 5019941 5021092 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094, 6092059; Product type e : enzyme; IS30 transposase; KpLE2 phage-like element complement(5019941..5021092) Escherichia coli UMN026 7155512 YP_002415435.1 CDS insM NC_011751.1 5021049 5021417 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS600 complement(5021049..5021417) Escherichia coli UMN026 7157706 YP_002415436.1 CDS insO NC_011751.1 5021433 5022029 D Evidence 7 : Gene remnant; Product type pe : putative enzyme; transposase ORF B (fragment), IS911 5021433..5022029 Escherichia coli UMN026 7156835 YP_002415437.1 CDS yjhV NC_011751.1 5022195 5022608 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5022195..5022608 Escherichia coli UMN026 7156837 YP_002415438.1 CDS fecE NC_011751.1 5023165 5023932 R Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit complement(5023165..5023932) Escherichia coli UMN026 7159415 YP_002415439.1 CDS ECUMN_4856 NC_011751.1 5023736 5023900 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5023736..5023900 Escherichia coli UMN026 7156328 YP_002415440.1 CDS fecD NC_011751.1 5023933 5024889 R Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD complement(5023933..5024889) Escherichia coli UMN026 7155513 YP_002415441.1 CDS fecC NC_011751.1 5024886 5025884 R part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate permease complement(5024886..5025884) Escherichia coli UMN026 7156327 YP_002415442.1 CDS fecB NC_011751.1 5025881 5026783 R part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit complement(5025881..5026783) Escherichia coli UMN026 7156326 YP_002415443.1 CDS fecA NC_011751.1 5026828 5029152 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90105402, 91072220, 92269759, 2836368; Product type t : transporter; ferric citrate outer membrane transporter; KpLE2 phage-like element complement(5026828..5029152) Escherichia coli UMN026 7156325 YP_002415444.1 CDS fecR NC_011751.1 5029239 5030192 R with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR complement(5029239..5030192) Escherichia coli UMN026 7156324 YP_002415445.1 CDS fecI NC_011751.1 5030189 5030710 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI complement(5030189..5030710) Escherichia coli UMN026 7156330 YP_002415446.1 CDS insA NC_011751.1 5031002 5031277 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1849492; Product type r : regulator; IS1 repressor protein InsA; KpLE2 phage-like element 5031002..5031277 Escherichia coli UMN026 7156329 YP_002415447.1 CDS ECUMN_4866 NC_011751.1 5032881 5033072 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5032881..5033072) Escherichia coli UMN026 7156824 YP_002415448.1 CDS ECUMN_4867 NC_011751.1 5033436 5034809 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5033436..5034809 Escherichia coli UMN026 7155514 YP_002415449.1 CDS ECUMN_4868 NC_011751.1 5035048 5036433 R Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase complement(5035048..5036433) Escherichia coli UMN026 7155515 YP_002415450.1 CDS ECUMN_4869 NC_011751.1 5036483 5036830 R Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family complement(5036483..5036830) Escherichia coli UMN026 7155516 YP_002415451.1 CDS ECUMN_4870 NC_011751.1 5036827 5037228 R Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase, IS3 family complement(5036827..5037228) Escherichia coli UMN026 7155517 YP_002415452.1 CDS ECUMN_4871 NC_011751.1 5037562 5038083 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5037562..5038083) Escherichia coli UMN026 7155518 YP_002415453.1 CDS ECUMN_4872 NC_011751.1 5037984 5038391 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5037984..5038391) Escherichia coli UMN026 7155519 YP_002415454.1 CDS ECUMN_4873 NC_011751.1 5038645 5039250 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5038645..5039250) Escherichia coli UMN026 7155520 YP_002415455.1 CDS ECUMN_4875 NC_011751.1 5039828 5039995 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5039828..5039995) Escherichia coli UMN026 7155521 YP_002415456.1 CDS ECUMN_4876 NC_011751.1 5040543 5040944 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5040543..5040944 Escherichia coli UMN026 7155522 YP_002415457.1 CDS ECUMN_4877 NC_011751.1 5041024 5041641 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5041024..5041641 Escherichia coli UMN026 7155523 YP_002415458.1 CDS ECUMN_4878 NC_011751.1 5041963 5043516 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(5041963..5043516) Escherichia coli UMN026 7155524 YP_002415459.1 CDS ECUMN_4879 NC_011751.1 5044091 5044351 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 5044091..5044351 Escherichia coli UMN026 7155525 YP_002415460.1 CDS ECUMN_4880 NC_011751.1 5044639 5045550 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5044639..5045550 Escherichia coli UMN026 7155526 YP_002415461.1 CDS flu NC_011751.1 5045922 5049041 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392470, 97257509, 99212225, 2661530, 9298646; Product type h : extrachromosomal origin; antigen 43 (Ag43) phase-variable biofilm formation autotransporter; CP4-44 prophage 5045922..5049041 Escherichia coli UMN026 7155527 YP_002415462.1 CDS ECUMN_4882 NC_011751.1 5049076 5049270 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5049076..5049270 Escherichia coli UMN026 7156418 YP_002415463.1 CDS ECUMN_4883 NC_011751.1 5049425 5050243 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5049425..5050243 Escherichia coli UMN026 7155528 YP_002415464.1 CDS ECUMN_4884 NC_011751.1 5050204 5051058 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5050204..5051058 Escherichia coli UMN026 7155529 YP_002415465.1 CDS yeeS NC_011751.1 5051059 5051550 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor; putative DNA repair protein; CP4-44 prophage 5051059..5051550 Escherichia coli UMN026 7155530 YP_002415466.1 CDS yeeT NC_011751.1 5051613 5051834 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5051613..5051834 Escherichia coli UMN026 7158809 YP_002415467.1 CDS ECUMN_4887 NC_011751.1 5051834 5051947 D Evidence 6 : Doubtful CDS; hypothetical protein 5051834..5051947 Escherichia coli UMN026 7158811 YP_002415468.1 CDS ECUMN_4888 NC_011751.1 5051889 5052365 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5051889..5052365 Escherichia coli UMN026 7155531 YP_002415469.1 CDS mtnK NC_011751.1 5053293 5054552 D phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway; methylthioribose kinase 5053293..5054552 Escherichia coli UMN026 7155532 YP_002415470.1 CDS mtnA NC_011751.1 5054562 5055677 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15102328; Product type e : enzyme; methyl-thioribose-1-phosphate isomerase 5054562..5055677 Escherichia coli UMN026 7157196 YP_002415471.1 CDS mtnB NC_011751.1 5055708 5056349 D catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 5055708..5056349 Escherichia coli UMN026 7157194 YP_002415472.1 CDS ECUMN_4892 NC_011751.1 5056453 5057457 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative integral membrane protein 5056453..5057457 Escherichia coli UMN026 7157195 YP_002415473.1 CDS yjhU NC_011751.1 5057498 5058484 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator; KpLE2 phage-like element complement(5057498..5058484) Escherichia coli UMN026 7155533 YP_002415474.1 CDS ECUMN_4894 NC_011751.1 5058584 5058775 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5058584..5058775) Escherichia coli UMN026 7159414 YP_002415475.1 CDS yjhF NC_011751.1 5058831 5060180 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter; KpLE2 phage-like element complement(5058831..5060180) Escherichia coli UMN026 7155534 YP_002415476.1 CDS yjhG NC_011751.1 5060287 5062254 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(5060287..5062254) Escherichia coli UMN026 7159405 YP_002415477.1 CDS yjhH NC_011751.1 5062265 5063170 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11425723; Product type pe : putative enzyme; putative lyase/synthase (dapA-like); KpLE2 phage-like element complement(5062265..5063170) Escherichia coli UMN026 7159406 YP_002415478.1 CDS yjhI NC_011751.1 5063175 5063963 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator; KpLE2 phage-like element complement(5063175..5063963) Escherichia coli UMN026 7159407 YP_002415479.1 CDS sgcR NC_011751.1 5064266 5065048 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator; KpLE2 phage-like element complement(5064266..5065048) Escherichia coli UMN026 7159408 YP_002415480.1 CDS sgcE NC_011751.1 5065065 5065697 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; epimerase complement(5065065..5065697) Escherichia coli UMN026 7157919 YP_002415481.1 CDS sgcA NC_011751.1 5065709 5066140 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative phosphotransferase enzyme IIA component; KpLE2 phage-like element complement(5065709..5066140) Escherichia coli UMN026 7157917 YP_002415482.1 CDS sgcQ NC_011751.1 5066271 5067077 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleoside triphosphatase; KpLE2 phage-like element complement(5066271..5067077) Escherichia coli UMN026 7157858 YP_002415483.1 CDS sgcC NC_011751.1 5067090 5068403 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative phosphotransferase enzyme IIC component; KpLE2 phage-like element complement(5067090..5068403) Escherichia coli UMN026 7157918 YP_002415484.1 CDS sgcB NC_011751.1 5068415 5068693 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIB component of PTS; KpLE2 phage-like element complement(5068415..5068693) Escherichia coli UMN026 7157916 YP_002415485.1 CDS sgcX NC_011751.1 5068690 5069811 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative endoglucanase with Zn-dependent exopeptidase domain; KpLE2 phage-like element complement(5068690..5069811) Escherichia coli UMN026 7157915 YP_002415486.1 CDS yjhP NC_011751.1 5070597 5071343 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase; KpLE2 phage-like element complement(5070597..5071343) Escherichia coli UMN026 7157920 YP_002415487.1 CDS yjhQ NC_011751.1 5071399 5071944 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase; KpLE2 phage-like element complement(5071399..5071944) Escherichia coli UMN026 7159409 YP_002415488.1 CDS yjhX NC_011751.1 5071956 5072213 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5071956..5072213) Escherichia coli UMN026 7159410 YP_002415489.1 CDS ECUMN_4909 NC_011751.1 5072704 5072835 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5072704..5072835) Escherichia coli UMN026 7159416 YP_002415490.1 CDS yjhR NC_011751.1 5073175 5074191 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96367099; Product type pf : putative factor; putative frameshift suppressor; KpLE2 phage-like element 5073175..5074191 Escherichia coli UMN026 7155536 YP_002415491.1 CDS ECUMN_4912 NC_011751.1 5074306 5074482 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5074306..5074482) Escherichia coli UMN026 7159411 YP_002415492.1 CDS insH NC_011751.1 5074342 5075358 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage 5074342..5075358 Escherichia coli UMN026 7155537 YP_002415493.1 CDS yjhS NC_011751.1 5075973 5076953 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5075973..5076953) Escherichia coli UMN026 7156833 YP_002415494.1 CDS yjhT NC_011751.1 5077018 5078124 R Evidence 4 : Homologs of previously reported genes of unknown function; N-acetylneuraminic acid mutarotase complement(5077018..5078124) Escherichia coli UMN026 7159412 YP_002415495.1 CDS yjhA NC_011751.1 5078144 5078860 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15743943; Product type t : transporter; N-acetylnuraminic acid outer membrane channel protein complement(5078144..5078860) Escherichia coli UMN026 7159413 YP_002415496.1 CDS ECUMN_4917 NC_011751.1 5079229 5079378 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5079229..5079378 Escherichia coli UMN026 7159402 YP_002415497.1 CDS ECUMN_4918 NC_011751.1 5079660 5080055 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5079660..5080055) Escherichia coli UMN026 7155538 YP_002415498.1 CDS fimB NC_011751.1 5080316 5080918 D inversion of on/off regulator of fimA; tyrosine recombinase 5080316..5080918 Escherichia coli UMN026 7155539 YP_002415499.1 CDS fimE NC_011751.1 5081396 5081992 D inversion of on/off regulator of fimA; tyrosine recombinase 5081396..5081992 Escherichia coli UMN026 7156357 YP_002415500.1 CDS fimA NC_011751.1 5082474 5083022 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6146599, 6147250, 90220509, 93106965, 2858471, 6123483; Product type s : structure; major type 1 subunit fimbrin 5082474..5083022 Escherichia coli UMN026 7156360 YP_002415501.1 CDS fimI NC_011751.1 5083087 5083626 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12897022, 11673421, 6147250; Product type s : structure; type 1 pilus biosynthesis fimbrial protein 5083087..5083626 Escherichia coli UMN026 7156356 YP_002415502.1 CDS fimC NC_011751.1 5083663 5084388 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20450729, 90220509, 93155127, 93391362, 1363735, 8104335, 8636962, 9783748; Product type f : factor; chaperone, periplasmic 5083663..5084388 Escherichia coli UMN026 7156364 YP_002415503.1 CDS fimD NC_011751.1 5084455 5087091 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12842468, 90220509, 1970114; Product type f : factor; outer membrane usher protein, type 1 fimbrial synthesis 5084455..5087091 Escherichia coli UMN026 7156358 YP_002415504.1 CDS fimF NC_011751.1 5087101 5087631 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 92394896, 1970114, 2890081; Product type s : structure; minor component of type 1 fimbriae 5087101..5087631 Escherichia coli UMN026 7156359 YP_002415505.1 CDS fimG NC_011751.1 5087644 5088147 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 92394896, 2890081; Product type s : structure; minor component of type 1 fimbriae 5087644..5088147 Escherichia coli UMN026 7156361 YP_002415506.1 CDS fimH NC_011751.1 5088167 5089069 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 93155127, 93391362, 1971261, 2890081, 2900235; Product type s : structure; minor component of type 1 fimbriae 5088167..5089069 Escherichia coli UMN026 7156362 YP_002415507.1 CDS gntP NC_011751.1 5089312 5090655 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125229, 15516583, 8550444; Product type t : transporter; fructuronate transporter complement(5089312..5090655) Escherichia coli UMN026 7156363 YP_002415508.1 CDS ECUMN_4929 NC_011751.1 5090735 5091043 D Evidence 6 : Doubtful CDS; hypothetical protein 5090735..5091043 Escherichia coli UMN026 7156596 YP_002415509.1 CDS uxuA NC_011751.1 5090995 5092179 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5090995..5092179 Escherichia coli UMN026 7155540 YP_002415510.1 CDS uxuB NC_011751.1 5092260 5093720 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73203083, 77222076, 14401695; Product type e : enzyme; D-mannonate oxidoreductase, NAD-binding 5092260..5093720 Escherichia coli UMN026 7158206 YP_002415511.1 CDS uxuR NC_011751.1 5093935 5094708 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5093935..5094708 Escherichia coli UMN026 7158207 YP_002415512.1 CDS yjiC NC_011751.1 5094849 5095679 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5094849..5095679) Escherichia coli UMN026 7158208 YP_002415513.1 CDS ECUMN_4934 NC_011751.1 5096243 5096386 D Evidence 6 : Doubtful CDS; hypothetical protein 5096243..5096386 Escherichia coli UMN026 7159418 YP_002415514.1 CDS iraD NC_011751.1 5096352 5096744 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5096352..5096744 Escherichia coli UMN026 7155541 YP_002415515.1 CDS yjiE NC_011751.1 5096737 5097648 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(5096737..5097648) Escherichia coli UMN026 7159419 YP_002415516.1 CDS iadA NC_011751.1 5097713 5098885 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95181377, 7876157; Product type e : enzyme; isoaspartyl dipeptidase complement(5097713..5098885) Escherichia coli UMN026 7159420 YP_002415517.1 CDS yjiG NC_011751.1 5098898 5099359 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5098898..5099359) Escherichia coli UMN026 7156778 YP_002415518.1 CDS yjiH NC_011751.1 5099356 5100039 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5099356..5100039) Escherichia coli UMN026 7159421 YP_002415519.1 CDS kptA NC_011751.1 5100289 5100843 D in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 5100289..5100843 Escherichia coli UMN026 7159422 YP_002415520.1 CDS yjiJ NC_011751.1 5100856 5102034 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5100856..5102034) Escherichia coli UMN026 7156917 YP_002415521.1 CDS yjiK NC_011751.1 5102102 5103070 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5102102..5103070) Escherichia coli UMN026 7159423 YP_002415522.1 CDS ECUMN_4944 NC_011751.1 5103027 5103284 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5103027..5103284) Escherichia coli UMN026 7159424 YP_002415523.1 CDS hgdC NC_011751.1 5103281 5104048 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8365476, 7607244, 15654892; Product type e : enzyme; ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase complement(5103281..5104048) Escherichia coli UMN026 7155542 YP_002415524.1 CDS yjiM NC_011751.1 5104058 5105209 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3691501, 11106419; Product type pe : putative enzyme; putative 2-hydroxyglutaryl-CoA dehydratase (hgdB-like) complement(5104058..5105209) Escherichia coli UMN026 7156668 YP_002415525.1 CDS yjiN NC_011751.1 5105325 5106605 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5105325..5106605) Escherichia coli UMN026 7159425 YP_002415526.1 CDS yjiO NC_011751.1 5106646 5107878 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug efflux system protein complement(5106646..5107878) Escherichia coli UMN026 7159426 YP_002415527.1 CDS ECUMN_4949 NC_011751.1 5108357 5109277 D Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 5108357..5109277 Escherichia coli UMN026 7159427 YP_002415528.1 CDS yjiR NC_011751.1 5109521 5110933 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator/putative aminotransferase complement(5109521..5110933) Escherichia coli UMN026 7155543 YP_002415529.1 CDS yjgt NC_011751.1 5111725 5115063 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5111725..5115063 Escherichia coli UMN026 7159428 YP_002415530.1 CDS ECUMN_4953 NC_011751.1 5115076 5121420 D Evidence 4 : Homologs of previously reported genes of unknown function; putative DEAD-box helicase-like protein 5115076..5121420 Escherichia coli UMN026 7159401 YP_002415531.1 CDS mcrC NC_011751.1 5121477 5122523 R McrC protein together with McrB forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; MrcC modulates the specificty of McrB and has DNA cleavage activity; 5-methylcytosine-specific restriction enzyme subunit McrC complement(5121477..5122523) Escherichia coli UMN026 7155544 YP_002415532.1 CDS mcrB NC_011751.1 5122523 5123902 R McrB protein together with McrC forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; 5-methylcytosine-specific restriction enzyme subunit McrB complement(5122523..5123902) Escherichia coli UMN026 7157067 YP_002415533.1 CDS yjiW NC_011751.1 5124064 5124462 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(5124064..5124462) Escherichia coli UMN026 7157066 YP_002415534.1 CDS hsdS NC_011751.1 5124633 5126027 R specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS complement(5124633..5126027) Escherichia coli UMN026 7157859 YP_002415535.1 CDS hsdM NC_011751.1 5126024 5127613 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88118919, 91216450, 3323532; Product type e : enzyme; DNA methylase M complement(5126024..5127613) Escherichia coli UMN026 7156719 YP_002415536.1 CDS hsdR NC_011751.1 5127814 5131326 R restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R complement(5127814..5131326) Escherichia coli UMN026 7156717 YP_002415537.1 CDS mrr NC_011751.1 5131514 5132428 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193234, 91317743, 1650347; Product type e : enzyme; methylated adenine and cytosine restriction protein 5131514..5132428 Escherichia coli UMN026 7156718 YP_002415538.1 CDS yjiA NC_011751.1 5132474 5133430 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14696199; Product type pe : putative enzyme; putative GTP-binding protein YjiA complement(5132474..5133430) Escherichia coli UMN026 7157183 YP_002415539.1 CDS yjiX NC_011751.1 5133441 5133644 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5133441..5133644) Escherichia coli UMN026 7159417 YP_002415540.1 CDS yjiY NC_011751.1 5133694 5135844 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5133694..5135844) Escherichia coli UMN026 7159430 YP_002415541.1 CDS ECUMN_4964 NC_011751.1 5136012 5136158 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5136012..5136158) Escherichia coli UMN026 7159431 YP_002415542.1 CDS hpaC NC_011751.1 5136237 5136749 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10633095; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase small component complement(5136237..5136749) Escherichia coli UMN026 7155545 YP_002415543.1 CDS hpaB NC_011751.1 5136767 5138329 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10653707; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase large component complement(5136767..5138329) Escherichia coli UMN026 7156703 YP_002415544.1 CDS hpaA NC_011751.1 5138580 5139470 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403; Product type r : regulator; regulator of the 4HPA-hydroxylase operon complement(5138580..5139470) Escherichia coli UMN026 7156702 YP_002415545.1 CDS ECUMN_4968 NC_011751.1 5139480 5140916 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8550403, 14744977; Product type pt : putative transporter; putative 4-hydroxyphenylacetate permease hpaX complement(5139480..5140916) Escherichia coli UMN026 7156701 YP_002415546.1 CDS hpaI NC_011751.1 5141031 5141837 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8529896, 8550403; Product type e : enzyme; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase complement(5141031..5141837) Escherichia coli UMN026 7155546 YP_002415547.1 CDS insG NC_011751.1 5141868 5143214 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative IS4 transposase; KpLE2 phage-like element complement(5141868..5143214) Escherichia coli UMN026 7156709 YP_002415548.1 CDS hpaH NC_011751.1 5143253 5144089 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403, 9492273; Product type e : enzyme; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase complement(5143253..5144089) Escherichia coli UMN026 7156829 YP_002415549.1 CDS hpaF NC_011751.1 5144139 5144519 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2194841; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate delta-isomerase complement(5144139..5144519) Escherichia coli UMN026 7156708 YP_002415550.1 CDS hpaD NC_011751.1 5144529 5145380 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403; Product type e : enzyme; 3,4-dihydroxyphenylacetate 2,3-dioxygenase complement(5144529..5145380) Escherichia coli UMN026 7156706 YP_002415551.1 CDS hpaE NC_011751.1 5145382 5146848 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7737515, 2061311, 8550403; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase complement(5145382..5146848) Escherichia coli UMN026 7156704 YP_002415552.1 CDS hpaG NC_011751.1 5146845 5148140 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8223600, 8384293, 11863436; Product type e : enzyme; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase complement(5146845..5148140) Escherichia coli UMN026 7156705 YP_002415553.1 CDS hpaR NC_011751.1 5148352 5148852 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8384293, 8550403; Product type r : regulator; 4-hydroxyphenylacetate degradative operon repressor 5148352..5148852 Escherichia coli UMN026 7156707 YP_002415554.1 CDS tsr NC_011751.1 5148971 5150635 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 89034150, 91317710, 10466731, 2033064, 6213619, 6402709, 8384293; Product type r : regulator; methyl-accepting chemotaxis protein I, serine sensor receptor 5148971..5150635 Escherichia coli UMN026 7156710 YP_002415555.1 CDS yjjM NC_011751.1 5152260 5153174 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator complement(5152260..5153174) Escherichia coli UMN026 7159433 YP_002415556.1 CDS yjjN NC_011751.1 5153313 5154335 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 5153313..5154335 Escherichia coli UMN026 7159438 YP_002415557.1 CDS mdoB NC_011751.1 5154475 5156766 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(5154475..5156766) Escherichia coli UMN026 7159439 YP_002415558.1 CDS yjjA NC_011751.1 5157020 5157514 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5157020..5157514) Escherichia coli UMN026 7157072 YP_002415559.1 CDS dnaC NC_011751.1 5157563 5158300 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(5157563..5158300) Escherichia coli UMN026 7159434 YP_002415560.1 CDS dnaT NC_011751.1 5158303 5158842 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(5158303..5158842) Escherichia coli UMN026 7156185 YP_002415561.2 CDS ECUMN_4986 NC_011751.1 5158949 5159422 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5158949..5159422) Escherichia coli UMN026 7156192 YP_002415562.1 CDS yjjP NC_011751.1 5159413 5160183 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5159413..5160183) Escherichia coli UMN026 7155547 YP_002415563.1 CDS yjjQ NC_011751.1 5160802 5161527 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 5160802..5161527 Escherichia coli UMN026 7159440 YP_002415564.1 CDS bglJ NC_011751.1 5161539 5162162 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5161539..5162162 Escherichia coli UMN026 7159441 YP_002415565.1 CDS fhuF NC_011751.1 5162200 5162988 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11931550, 14756576, 3323834, 9990318; Product type c : carrier; ferric iron reductase complement(5162200..5162988) Escherichia coli UMN026 7155874 YP_002415566.1 CDS ECUMN_4991 NC_011751.1 5163018 5163365 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5163018..5163365 Escherichia coli UMN026 7156349 YP_002415567.1 CDS rsmC NC_011751.1 5164105 5165136 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(5164105..5165136) Escherichia coli UMN026 7155612 YP_002415568.1 CDS holD NC_011751.1 5165239 5165652 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5165239..5165652 Escherichia coli UMN026 7157798 YP_002415569.1 CDS rimI NC_011751.1 5165621 5166067 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5165621..5166067 Escherichia coli UMN026 7156699 YP_002415570.1 CDS yjjG NC_011751.1 5166082 5166759 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5166082..5166759 Escherichia coli UMN026 7157691 YP_002415571.1 CDS prfC NC_011751.1 5166850 5168439 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5166850..5168439 Escherichia coli UMN026 7159435 YP_002415572.1 CDS osmY NC_011751.1 5168832 5169437 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1317380, 8253679, 9298646, 9600841; Product type cp : cell process; periplasmic protein 5168832..5169437 Escherichia coli UMN026 7157519 YP_002415573.1 CDS ytjA NC_011751.1 5169546 5169725 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5169546..5169725 Escherichia coli UMN026 7157366 YP_002415574.1 CDS yjjU NC_011751.1 5169847 5170920 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative esterase 5169847..5170920 Escherichia coli UMN026 7159681 YP_002415575.1 CDS yjjV NC_011751.1 5170917 5171696 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative deoxyribonuclease YjjV 5170917..5171696 Escherichia coli UMN026 7159442 YP_002415576.1 CDS yjjW NC_011751.1 5172215 5173078 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative pyruvate formate lyase activating enzyme complement(5172215..5173078) Escherichia coli UMN026 7159443 YP_002415577.1 CDS yjjI NC_011751.1 5173050 5174600 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5173050..5174600) Escherichia coli UMN026 7159444 YP_002415578.1 CDS deoC NC_011751.1 5174858 5175637 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5174858..5175637 Escherichia coli UMN026 7159436 YP_002415579.1 CDS deoA NC_011751.1 5175863 5177185 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5175863..5177185 Escherichia coli UMN026 7156142 YP_002415580.1 CDS deoB NC_011751.1 5177237 5178460 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5177237..5178460 Escherichia coli UMN026 7156140 YP_002415581.1 CDS deoD NC_011751.1 5178517 5179236 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5178517..5179236 Escherichia coli UMN026 7156141 YP_002415582.1 CDS ECUMN_5009 NC_011751.1 5179420 5179647 R Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptionnal regulator complement(5179420..5179647) Escherichia coli UMN026 7156143 YP_002415583.1 CDS lplA NC_011751.1 5179679 5180695 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(5179679..5180695) Escherichia coli UMN026 7155549 YP_002415584.1 CDS ytjB NC_011751.1 5180723 5181367 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2684780; hypothetical protein complement(5180723..5181367) Escherichia coli UMN026 7157005 YP_002415585.1 CDS serB NC_011751.1 5181473 5182441 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5181473..5182441 Escherichia coli UMN026 7159682 YP_002415586.1 CDS radA NC_011751.1 5182490 5183872 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5182490..5183872 Escherichia coli UMN026 7157898 YP_002415587.1 CDS nadR NC_011751.1 5183893 5185125 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5183893..5185125 Escherichia coli UMN026 7157616 YP_002415588.1 CDS ECUMN_5015 NC_011751.1 5185312 5185437 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5185312..5185437) Escherichia coli UMN026 7157226 YP_002415589.1 CDS ECUMN_5016 NC_011751.1 5185352 5185537 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5185352..5185537) Escherichia coli UMN026 7155550 YP_002415590.1 CDS ECUMN_5017 NC_011751.1 5185586 5185798 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5185586..5185798) Escherichia coli UMN026 7155551 YP_002415591.1 CDS ECUMN_5018 NC_011751.1 5185956 5186372 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5185956..5186372) Escherichia coli UMN026 7155552 YP_002415592.1 CDS ECUMN_5019 NC_011751.1 5186398 5187297 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9537320; Product type pe : putative enzyme; putative 3-oxoacyl-[acyl-carrier-protein] reductase complement(5186398..5187297) Escherichia coli UMN026 7155553 YP_002415593.1 CDS ECUMN_5020 NC_011751.1 5187215 5188225 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Aldo/keto reductase complement(5187215..5188225) Escherichia coli UMN026 7155554 YP_002415594.1 CDS ECUMN_5021 NC_011751.1 5188266 5189246 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative HTH-type transcriptional regulator alsR 5188266..5189246 Escherichia coli UMN026 7155555 YP_002415595.1 CDS yjjK NC_011751.1 5189402 5191069 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(5189402..5191069) Escherichia coli UMN026 7155556 YP_002415596.1 CDS slt NC_011751.1 5191280 5193217 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5191280..5193217 Escherichia coli UMN026 7159437 YP_002415597.1 CDS trpR NC_011751.1 5193307 5193633 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5193307..5193633 Escherichia coli UMN026 7157935 YP_002415598.1 CDS yjjX NC_011751.1 5193627 5194151 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(5193627..5194151) Escherichia coli UMN026 7158123 YP_002415599.1 CDS ytjC NC_011751.1 5194194 5194841 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5194194..5194841 Escherichia coli UMN026 7159445 YP_002415600.1 CDS rob NC_011751.1 5194838 5195707 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20264525, 20309711, 93194823, 96405618, 8449900; Product type r : regulator; DNA-binding transcriptional activator complement(5194838..5195707) Escherichia coli UMN026 7159683 YP_002415601.1 CDS creA NC_011751.1 5195918 5196391 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3531171, 8449900; hypothetical protein 5195918..5196391 Escherichia coli UMN026 7157720 YP_002415602.1 CDS creB NC_011751.1 5196404 5197093 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5196404..5197093 Escherichia coli UMN026 7156010 YP_002415603.1 CDS creC NC_011751.1 5197093 5198517 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5197093..5198517 Escherichia coli UMN026 7156011 YP_002415604.1 CDS creD NC_011751.1 5198575 5199927 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88216172, 2835585, 2984198, 3531171; Product type m : membrane component; hypothetical protein 5198575..5199927 Escherichia coli UMN026 7156012 YP_002415605.1 CDS arcA NC_011751.1 5199987 5200703 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15028693, 21167794, 21317451, 91008980, 91358353, 92380937, 9514749, 9632255, 2984198, 7565118, 9298646; Product type r : regulator; two-component response regulator complement(5199987..5200703) Escherichia coli UMN026 7156013 YP_002415606.1 CDS yjtD NC_011751.1 5201339 5202025 D member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase 5201339..5202025 Escherichia coli UMN026 7155766 ECUMN_tRNA1 tRNA ECUMN_tRNA1 NC_011751.1 228231 228307 D tRNA-Ile 228231..228307 Escherichia coli UMN026 7154985 ECUMN_tRNA2 tRNA ECUMN_tRNA2 NC_011751.1 228350 228425 D tRNA-Ala 228350..228425 Escherichia coli UMN026 7155565 ECUMN_tRNA3 tRNA ECUMN_tRNA3 NC_011751.1 231779 231855 D tRNA-Asp 231779..231855 Escherichia coli UMN026 7155560 ECUMN_tRNA4 tRNA ECUMN_tRNA4 NC_011751.1 240002 240078 D tRNA-Asp 240002..240078 Escherichia coli UMN026 7156191 ECUMN_tRNA5 tRNA ECUMN_tRNA5 NC_011751.1 335532 335607 D tRNA-Thr 335532..335607 Escherichia coli UMN026 7157530 ECUMN_tRNA6 tRNA ECUMN_tRNA6 NC_011751.1 403247 403327 D tRNA-OTHER 403247..403327 Escherichia coli UMN026 7158322 ECUMN_tRNA7 tRNA ECUMN_tRNA7 NC_011751.1 644851 644927 D tRNA-Arg 644851..644927 Escherichia coli UMN026 7156365 ECUMN_tRNA88 tRNA ECUMN_tRNA88 NC_011751.1 808736 808810 R tRNA-Gln complement(808736..808810) Escherichia coli UMN026 7158157 ECUMN_tRNA87 tRNA ECUMN_tRNA87 NC_011751.1 808848 808922 R tRNA-Gln complement(808848..808922) Escherichia coli UMN026 7155651 ECUMN_tRNA86 tRNA ECUMN_tRNA86 NC_011751.1 808971 809047 R tRNA-Met complement(808971..809047) Escherichia coli UMN026 7155650 ECUMN_tRNA85 tRNA ECUMN_tRNA85 NC_011751.1 809063 809137 R tRNA-Gln complement(809063..809137) Escherichia coli UMN026 7155649 ECUMN_tRNA84 tRNA ECUMN_tRNA84 NC_011751.1 809172 809246 R tRNA-Gln complement(809172..809246) Escherichia coli UMN026 7155648 ECUMN_tRNA83 tRNA ECUMN_tRNA83 NC_011751.1 809270 809354 R tRNA-Leu complement(809270..809354) Escherichia coli UMN026 7154741 ECUMN_tRNA82 tRNA ECUMN_tRNA82 NC_011751.1 809364 809440 R tRNA-Met complement(809364..809440) Escherichia coli UMN026 7155646 ECUMN_tRNA8 tRNA ECUMN_tRNA8 NC_011751.1 888195 888270 D tRNA-Lys 888195..888270 Escherichia coli UMN026 7158423 ECUMN_tRNA9 tRNA ECUMN_tRNA9 NC_011751.1 888406 888481 D tRNA-Val 888406..888481 Escherichia coli UMN026 7155642 ECUMN_tRNA10 tRNA ECUMN_tRNA10 NC_011751.1 888484 888559 D tRNA-Lys 888484..888559 Escherichia coli UMN026 7155652 ECUMN_tRNA11 tRNA ECUMN_tRNA11 NC_011751.1 888611 888686 D tRNA-Val 888611..888686 Escherichia coli UMN026 7155566 ECUMN_tRNA12 tRNA ECUMN_tRNA12 NC_011751.1 888690 888765 D tRNA-Lys 888690..888765 Escherichia coli UMN026 7155567 ECUMN_tRNA13 tRNA ECUMN_tRNA13 NC_011751.1 888912 888987 D tRNA-Lys 888912..888987 Escherichia coli UMN026 7155568 ECUMN_tRNA14 tRNA ECUMN_tRNA14 NC_011751.1 889021 889096 D tRNA-Lys 889021..889096 Escherichia coli UMN026 7155569 ECUMN_tRNA81 tRNA ECUMN_tRNA81 NC_011751.1 1115007 1115094 R tRNA-Ser complement(1115007..1115094) Escherichia coli UMN026 7154850 ECUMN_tRNA80 tRNA ECUMN_tRNA80 NC_011751.1 1213806 1213893 R tRNA-Ser complement(1213806..1213893) Escherichia coli UMN026 7154855 ECUMN_tRNA79 tRNA ECUMN_tRNA79 NC_011751.1 1262465 1262552 R tRNA-Ser complement(1262465..1262552) Escherichia coli UMN026 7154860 ECUMN_tRNA78 tRNA ECUMN_tRNA78 NC_011751.1 1540737 1540821 R tRNA-Tyr complement(1540737..1540821) Escherichia coli UMN026 7157816 ECUMN_tRNA77 tRNA ECUMN_tRNA77 NC_011751.1 1540856 1540940 R tRNA-Tyr complement(1540856..1540940) Escherichia coli UMN026 7155640 ECUMN_tRNA15 tRNA ECUMN_tRNA15 NC_011751.1 1981213 1981289 D tRNA-Val 1981213..1981289 Escherichia coli UMN026 7158680 ECUMN_tRNA16 tRNA ECUMN_tRNA16 NC_011751.1 1981294 1981370 D tRNA-Val 1981294..1981370 Escherichia coli UMN026 7155571 ECUMN_tRNA76 tRNA ECUMN_tRNA76 NC_011751.1 2225250 2225336 R tRNA-Leu complement(2225250..2225336) Escherichia coli UMN026 7158771 ECUMN_tRNA75 tRNA ECUMN_tRNA75 NC_011751.1 2225349 2225422 R tRNA-Cys complement(2225349..2225422) Escherichia coli UMN026 7155638 ECUMN_tRNA74 tRNA ECUMN_tRNA74 NC_011751.1 2225477 2225552 R tRNA-Gly complement(2225477..2225552) Escherichia coli UMN026 7155637 ECUMN_tRNA73 tRNA ECUMN_tRNA73 NC_011751.1 2276274 2276363 R tRNA-Ser complement(2276274..2276363) Escherichia coli UMN026 7159554 ECUMN_tRNA17 tRNA ECUMN_tRNA17 NC_011751.1 2277355 2277430 D tRNA-Asn 2277355..2277430 Escherichia coli UMN026 7158805 ECUMN_tRNA72 tRNA ECUMN_tRNA72 NC_011751.1 2357471 2357546 R tRNA-Asn complement(2357471..2357546) Escherichia coli UMN026 7155109 ECUMN_tRNA18 tRNA ECUMN_tRNA18 NC_011751.1 2359295 2359370 D tRNA-Asn 2359295..2359370 Escherichia coli UMN026 7158807 ECUMN_tRNA19 tRNA ECUMN_tRNA19 NC_011751.1 2361703 2361778 D tRNA-Asn 2361703..2361778 Escherichia coli UMN026 7157219 ECUMN_tRNA20 tRNA ECUMN_tRNA20 NC_011751.1 2588625 2588701 D tRNA-Pro 2588625..2588701 Escherichia coli UMN026 7158874 ECUMN_tRNA21 tRNA ECUMN_tRNA21 NC_011751.1 2765909 2765983 D tRNA-Arg 2765909..2765983 Escherichia coli UMN026 7158919 ECUMN_tRNA71 tRNA ECUMN_tRNA71 NC_011751.1 2809275 2809350 R tRNA-Ala complement(2809275..2809350) Escherichia coli UMN026 7158933 ECUMN_tRNA70 tRNA ECUMN_tRNA70 NC_011751.1 2809390 2809465 R tRNA-Ala complement(2809390..2809465) Escherichia coli UMN026 7155633 ECUMN_tRNA22 tRNA ECUMN_tRNA22 NC_011751.1 2812164 2812239 D tRNA-Val 2812164..2812239 Escherichia coli UMN026 7156582 ECUMN_tRNA23 tRNA ECUMN_tRNA23 NC_011751.1 2812284 2812359 D tRNA-Val 2812284..2812359 Escherichia coli UMN026 7155579 ECUMN_tRNA24 tRNA ECUMN_tRNA24 NC_011751.1 2812406 2812481 D tRNA-Val 2812406..2812481 Escherichia coli UMN026 7155580 ECUMN_tRNA25 tRNA ECUMN_tRNA25 NC_011751.1 2812486 2812561 D tRNA-Lys 2812486..2812561 Escherichia coli UMN026 7155581 ECUMN_tRNA69 tRNA ECUMN_tRNA69 NC_011751.1 3022365 3022440 R tRNA-Glu complement(3022365..3022440) Escherichia coli UMN026 7155131 ECUMN_tRNA68 tRNA ECUMN_tRNA68 NC_011751.1 3089116 3089191 R tRNA-Met complement(3089116..3089191) Escherichia coli UMN026 7155206 ECUMN_tRNA67 tRNA ECUMN_tRNA67 NC_011751.1 3123350 3123426 R tRNA-Arg complement(3123350..3123426) Escherichia coli UMN026 7159596 ECUMN_tRNA66 tRNA ECUMN_tRNA66 NC_011751.1 3123625 3123701 R tRNA-Arg complement(3123625..3123701) Escherichia coli UMN026 7155628 ECUMN_tRNA65 tRNA ECUMN_tRNA65 NC_011751.1 3123899 3123975 R tRNA-Arg complement(3123899..3123975) Escherichia coli UMN026 7155627 ECUMN_tRNA64 tRNA ECUMN_tRNA64 NC_011751.1 3124174 3124250 R tRNA-Arg complement(3124174..3124250) Escherichia coli UMN026 7155626 ECUMN_tRNA63 tRNA ECUMN_tRNA63 NC_011751.1 3124254 3124346 R tRNA-Ser complement(3124254..3124346) Escherichia coli UMN026 7155625 ECUMN_tRNA26 tRNA ECUMN_tRNA26 NC_011751.1 3253901 3253977 D tRNA-Met 3253901..3253977 Escherichia coli UMN026 7157139 ECUMN_tRNA27 tRNA ECUMN_tRNA27 NC_011751.1 3254011 3254087 D tRNA-Met 3254011..3254087 Escherichia coli UMN026 7155583 ECUMN_tRNA28 tRNA ECUMN_tRNA28 NC_011751.1 3254120 3254196 D tRNA-Met 3254120..3254196 Escherichia coli UMN026 7155584 ECUMN_tRNA29 tRNA ECUMN_tRNA29 NC_011751.1 3254229 3254305 D tRNA-Met 3254229..3254305 Escherichia coli UMN026 7155585 ECUMN_tRNA62 tRNA ECUMN_tRNA62 NC_011751.1 3321545 3321618 R tRNA-Gly complement(3321545..3321618) Escherichia coli UMN026 7155246 ECUMN_tRNA30 tRNA ECUMN_tRNA30 NC_011751.1 3445924 3445999 D tRNA-Phe 3445924..3445999 Escherichia coli UMN026 7159612 ECUMN_tRNA31 tRNA ECUMN_tRNA31 NC_011751.1 3670374 3670449 D tRNA-Met 3670374..3670449 Escherichia coli UMN026 7159098 ECUMN_tRNA61 tRNA ECUMN_tRNA61 NC_011751.1 3771415 3771491 R tRNA-Met complement(3771415..3771491) Escherichia coli UMN026 7159121 ECUMN_tRNA60 tRNA ECUMN_tRNA60 NC_011751.1 3775274 3775360 R tRNA-Leu complement(3775274..3775360) Escherichia coli UMN026 7159133 ECUMN_tRNA59 tRNA ECUMN_tRNA59 NC_011751.1 3869830 3869905 R tRNA-Thr complement(3869830..3869905) Escherichia coli UMN026 7155558 ECUMN_tRNA58 tRNA ECUMN_tRNA58 NC_011751.1 3873219 3873294 R tRNA-Ala complement(3873219..3873294) Escherichia coli UMN026 7155130 ECUMN_tRNA57 tRNA ECUMN_tRNA57 NC_011751.1 3873337 3873413 R tRNA-Ile complement(3873337..3873413) Escherichia coli UMN026 7155618 ECUMN_tRNA56 tRNA ECUMN_tRNA56 NC_011751.1 4171557 4171633 R tRNA-Pro complement(4171557..4171633) Escherichia coli UMN026 7155422 ECUMN_tRNA32 tRNA ECUMN_tRNA32 NC_011751.1 4296805 4296895 D tRNA-Sec 4296805..4296895 Escherichia coli UMN026 7159244 ECUMN_tRNA33 tRNA ECUMN_tRNA33 NC_011751.1 4430302 4430377 D tRNA-Glu 4430302..4430377 Escherichia coli UMN026 7154986 ECUMN_tRNA34 tRNA ECUMN_tRNA34 NC_011751.1 4433738 4433814 D tRNA-Asp 4433738..4433814 Escherichia coli UMN026 7155561 ECUMN_tRNA35 tRNA ECUMN_tRNA35 NC_011751.1 4433823 4433898 D tRNA-Trp 4433823..4433898 Escherichia coli UMN026 7155592 ECUMN_tRNA36 tRNA ECUMN_tRNA36 NC_011751.1 4468367 4468443 D tRNA-Arg 4468367..4468443 Escherichia coli UMN026 7159276 ECUMN_tRNA37 tRNA ECUMN_tRNA37 NC_011751.1 4468502 4468577 D tRNA-His 4468502..4468577 Escherichia coli UMN026 7155594 ECUMN_tRNA38 tRNA ECUMN_tRNA38 NC_011751.1 4468598 4468684 D tRNA-Leu 4468598..4468684 Escherichia coli UMN026 7155595 ECUMN_tRNA39 tRNA ECUMN_tRNA39 NC_011751.1 4468727 4468803 D tRNA-Pro 4468727..4468803 Escherichia coli UMN026 7155596 ECUMN_tRNA40 tRNA ECUMN_tRNA40 NC_011751.1 4523799 4523875 D tRNA-Ile 4523799..4523875 Escherichia coli UMN026 7154987 ECUMN_tRNA41 tRNA ECUMN_tRNA41 NC_011751.1 4523918 4523993 D tRNA-Ala 4523918..4523993 Escherichia coli UMN026 7155599 ECUMN_tRNA42 tRNA ECUMN_tRNA42 NC_011751.1 4657672 4657747 D tRNA-Glu 4657672..4657747 Escherichia coli UMN026 7154988 ECUMN_tRNA43 tRNA ECUMN_tRNA43 NC_011751.1 4664525 4664600 D tRNA-Thr 4664525..4664600 Escherichia coli UMN026 7155988 ECUMN_tRNA44 tRNA ECUMN_tRNA44 NC_011751.1 4664609 4664693 D tRNA-Tyr 4664609..4664693 Escherichia coli UMN026 7155602 ECUMN_tRNA45 tRNA ECUMN_tRNA45 NC_011751.1 4664810 4664884 D tRNA-Gly 4664810..4664884 Escherichia coli UMN026 7155603 ECUMN_tRNA46 tRNA ECUMN_tRNA46 NC_011751.1 4664891 4664966 D tRNA-Thr 4664891..4664966 Escherichia coli UMN026 7155604 ECUMN_tRNA47 tRNA ECUMN_tRNA47 NC_011751.1 4698766 4698841 D tRNA-Glu 4698766..4698841 Escherichia coli UMN026 7154989 ECUMN_tRNA55 tRNA ECUMN_tRNA55 NC_011751.1 4848121 4848196 R tRNA-Phe complement(4848121..4848196) Escherichia coli UMN026 7155479 ECUMN_tRNA48 tRNA ECUMN_tRNA48 NC_011751.1 4877050 4877125 D tRNA-Gly 4877050..4877125 Escherichia coli UMN026 7157362 ECUMN_tRNA49 tRNA ECUMN_tRNA49 NC_011751.1 4877283 4877358 D tRNA-Gly 4877283..4877358 Escherichia coli UMN026 7155607 ECUMN_tRNA50 tRNA ECUMN_tRNA50 NC_011751.1 4877394 4877469 D tRNA-Gly 4877394..4877469 Escherichia coli UMN026 7155608 ECUMN_tRNA51 tRNA ECUMN_tRNA51 NC_011751.1 4983917 4984001 D tRNA-Leu 4983917..4984001 Escherichia coli UMN026 7155484 ECUMN_tRNA54 tRNA ECUMN_tRNA54 NC_011751.1 5163404 5163490 R tRNA-Leu complement(5163404..5163490) Escherichia coli UMN026 7155548 ECUMN_tRNA53 tRNA ECUMN_tRNA53 NC_011751.1 5163525 5163611 R tRNA-Leu complement(5163525..5163611) Escherichia coli UMN026 7155614 ECUMN_tRNA52 tRNA ECUMN_tRNA52 NC_011751.1 5163640 5163726 R tRNA-Leu complement(5163640..5163726) Escherichia coli UMN026 7155613 ECUMN_16S_3 rRNA ECUMN_16S_3 NC_011751.1 226621 228162 D ribosomal RNA 16S 226621..228162 Escherichia coli UMN026 7156589 ECUMN_23S_3 rRNA ECUMN_23S_3 NC_011751.1 228609 231513 D ribosomal RNA 23S 228609..231513 Escherichia coli UMN026 7155576 ECUMN_5S_4 rRNA ECUMN_5S_4 NC_011751.1 231607 231726 D ribosomal RNA 5S 231607..231726 Escherichia coli UMN026 7155132 ECUMN_5S_3 rRNA ECUMN_5S_3 NC_011751.1 3019065 3019184 R ribosomal RNA 5S complement(3019065..3019184) Escherichia coli UMN026 7156907 ECUMN_23S_2 rRNA ECUMN_23S_2 NC_011751.1 3019276 3022180 R ribosomal RNA 23S complement(3019276..3022180) Escherichia coli UMN026 7155559 ECUMN_16S_2 rRNA ECUMN_16S_2 NC_011751.1 3022526 3024067 R ribosomal RNA 16S complement(3022526..3024067) Escherichia coli UMN026 7155630 ECUMN_5S_2 rRNA ECUMN_5S_2 NC_011751.1 3869677 3869789 R ribosomal RNA 5S complement(3869677..3869789) Escherichia coli UMN026 7155662 ECUMN_5S_1 rRNA ECUMN_5S_1 NC_011751.1 3869918 3870037 R ribosomal RNA 5S complement(3869918..3870037) Escherichia coli UMN026 7155619 ECUMN_23S_1 rRNA ECUMN_23S_1 NC_011751.1 3870131 3873035 R ribosomal RNA 23S complement(3870131..3873035) Escherichia coli UMN026 7155557 ECUMN_16S_1 rRNA ECUMN_16S_1 NC_011751.1 3873482 3875023 R ribosomal RNA 16S complement(3873482..3875023) Escherichia coli UMN026 7155617 ECUMN_16S_4 rRNA ECUMN_16S_4 NC_011751.1 4428675 4430216 D ribosomal RNA 16S 4428675..4430216 Escherichia coli UMN026 7159273 ECUMN_23S_4 rRNA ECUMN_23S_4 NC_011751.1 4430571 4433474 D ribosomal RNA 23S 4430571..4433474 Escherichia coli UMN026 7155591 ECUMN_5S_5 rRNA ECUMN_5S_5 NC_011751.1 4433566 4433685 D ribosomal RNA 5S 4433566..4433685 Escherichia coli UMN026 7155133 ECUMN_16S_5 rRNA ECUMN_16S_5 NC_011751.1 4522189 4523730 D ribosomal RNA 16S 4522189..4523730 Escherichia coli UMN026 7156656 ECUMN_23S_5 rRNA ECUMN_23S_5 NC_011751.1 4524177 4527078 D ribosomal RNA 23S 4524177..4527078 Escherichia coli UMN026 7155600 ECUMN_5S_6 rRNA ECUMN_5S_6 NC_011751.1 4527170 4527289 D ribosomal RNA 5S 4527170..4527289 Escherichia coli UMN026 7155134 ECUMN_16S_6 rRNA ECUMN_16S_6 NC_011751.1 4656045 4657586 D ribosomal RNA 16S 4656045..4657586 Escherichia coli UMN026 7157208 ECUMN_23S_6 rRNA ECUMN_23S_6 NC_011751.1 4657941 4660845 D ribosomal RNA 23S 4657941..4660845 Escherichia coli UMN026 7155601 ECUMN_5S_7 rRNA ECUMN_5S_7 NC_011751.1 4660940 4661059 D ribosomal RNA 5S 4660940..4661059 Escherichia coli UMN026 7155135 ECUMN_16S_7 rRNA ECUMN_16S_7 NC_011751.1 4697139 4698680 D ribosomal RNA 16S 4697139..4698680 Escherichia coli UMN026 7157578 ECUMN_23S_7 rRNA ECUMN_23S_7 NC_011751.1 4699035 4701939 D ribosomal RNA 23S 4699035..4701939 Escherichia coli UMN026 7155606 ECUMN_5S_8 rRNA ECUMN_5S_8 NC_011751.1 4702034 4702153 D ribosomal RNA 5S 4702034..4702153 Escherichia coli UMN026 7155136