-- dump date   	20120504_144657
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
393115000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
393115000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
393115000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115000004	Walker A motif; other site
393115000005	ATP binding site [chemical binding]; other site
393115000006	Walker B motif; other site
393115000007	arginine finger; other site
393115000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
393115000009	DnaA box-binding interface [nucleotide binding]; other site
393115000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
393115000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
393115000012	putative DNA binding surface [nucleotide binding]; other site
393115000013	dimer interface [polypeptide binding]; other site
393115000014	beta-clamp/clamp loader binding surface; other site
393115000015	beta-clamp/translesion DNA polymerase binding surface; other site
393115000016	Similar to Q881T0 Proline/betaine transporter from Pseudomonas syringae (438 aa). FASTA: opt: 271 Z-score: 314.7 E(): 1.2e-09 Smith-Waterman score: 271; 37.594 identity in 133 aa overlap. Truncation at N-terminal according to FASTA hits ORF ftt0003c
393115000017	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000018	Integrase core domain; Region: rve; cl01316
393115000019	Similar to Q92TE2 Probable succinate-semialdehyde dehydrogenase from Rhizobium meliloti (484 aa). FASTA: opt: 622 Z-score: 785.3 E(): 6.9e-36 Smith-Waterman score: 622; 55.294 identity in 170 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element causing a truncation at N-terminal
393115000020	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115000021	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
393115000022	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
393115000023	dimer interface [polypeptide binding]; other site
393115000024	anticodon binding site; other site
393115000025	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of the...; Region: AspRS_core; cd00777
393115000026	homodimer interface [polypeptide binding]; other site
393115000027	motif 1; other site
393115000028	active site
393115000029	motif 2; other site
393115000030	GAD domain; Region: GAD; pfam02938
393115000031	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it attaches...; Region: class_II_aaRS-like_core; cl00268
393115000032	active site
393115000033	motif 3; other site
393115000034	Similar to Q8A5U0 Glycosyltransferase from Bacteriodes thetaiotamicron (323 aa). FASTA: opt: 175 Z-score: 241.3 E(): 1.4e-05 Smith-Waterman score: 175; 38.144 identity in 97 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element causing a truncation at the C-terminal ORF ftt0008
393115000035	ISFtu1, fragment. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. Deletion of carboxy terminal region between aa 135 and 238 relative to full length ISFtu1
393115000036	Similar to MTH3_HAEAE (P20589) Modification methylase HaeIII from Haemophilus aegyptius (330 aa). FASTA: opt: 652 Z-score: 839.7 E(): 6.4e-39 Smith-Waterman score: 652; 57.310 identity in 171 aa overlap. This CDS is disrupted by the insertion of a fragment of an ISFtu1 element causing a truncation at N-terminal ORF ftt0010
393115000037	Similar to O68582 FnuDI restriction endonuclease from Fusobacterium nucleatum (284 aa). FASTA: .opt: 881 Z-score: 1029.1 E(): 1.8e-49 Smith-Waterman score: 881; 50.178 identity in 281 aa overlap . Contains an in-frame stop codon after aa 75 ORF ftt0011
393115000038	Similar to Q92C69 Hypothetical protein lin1322 from Listeria innocua (290 aa). FASTA: opt: 601 Z-score: 755.7 E(): 3e-34 Smith-Waterman score: 601; 31.507 identity in 292 aa. Contains a frameshift after aa 139. ORF ftt0012
393115000039	adenylosuccinate lyase; Provisional; Region: PRK07492
393115000040	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
393115000041	tetramer interface [polypeptide binding]; other site
393115000042	active site
393115000043	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
393115000044	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
393115000045	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115000046	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115000047	Glu-tRNAGln amidotransferase C subunit; Region: Glu-tRNAGln; cl00495
393115000048	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
393115000049	Amidase; Region: Amidase; cl11426
393115000050	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
393115000051	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
393115000052	GatB domain; Region: GatB_Yqey; cl11497
393115000053	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
393115000054	active site
393115000055	oxyanion hole [active]
393115000056	catalytic triad [active]
393115000057	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115000058	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000059	putative substrate translocation pore; other site
393115000060	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
393115000061	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme MccE; Region: PLPDE_III_MccE_like; cd06841
393115000062	dimer interface [polypeptide binding]; other site
393115000063	active site
393115000064	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115000065	catalytic residues [active]
393115000066	substrate binding site [chemical binding]; other site
393115000067	drug efflux system protein MdtG; Provisional; Region: PRK09874
393115000068	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000069	IucA / IucC family; Region: IucA_IucC; pfam04183
393115000070	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
393115000071	ferric uptake regulator; Provisional; Region: fur; PRK09462
393115000072	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
393115000073	metal binding site 2 [ion binding]; metal-binding site
393115000074	putative DNA binding helix; other site
393115000075	metal binding site 1 [ion binding]; metal-binding site
393115000076	dimer interface [polypeptide binding]; other site
393115000077	structural Zn2+ binding site [ion binding]; other site
393115000078	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
393115000079	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl15792
393115000080	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl15771
393115000081	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; cl00417
393115000082	Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Region: Complex1_49kDa; pfam00346
393115000083	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
393115000084	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
393115000085	putative dimer interface [polypeptide binding]; other site
393115000086	[2Fe-2S] cluster binding site [ion binding]; other site
393115000087	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
393115000088	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
393115000089	SLBB domain; Region: SLBB; pfam10531
393115000090	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; cl11211
393115000091	NADH dehydrogenase subunit G; Validated; Region: PRK09129
393115000092	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
393115000093	catalytic loop [active]
393115000094	iron binding site [ion binding]; other site
393115000095	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; cl11210
393115000096	MopB_NDH-1_NuoG2: The second domain of the NuoG subunit of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1), found in beta- and gammaproteobacteria. The NDH-1 is the first energy-transducting complex in the respiratory chain and functions as...; Region: MopB_NDH-1_NuoG2; cd02772
393115000097	NADH dehydrogenase; Region: NADHdh; cl00469
393115000098	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
393115000099	4Fe-4S binding domain; Region: Fer4; cl02805
393115000100	4Fe-4S binding domain; Region: Fer4; cl02805
393115000101	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
393115000102	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; Region: Oxidored_q2; cl00492
393115000103	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
393115000104	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
393115000105	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; cl14187
393115000106	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
393115000107	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; cl14187
393115000108	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
393115000109	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; cl14187
393115000110	Membrane fusogenic activity; Region: BMFP; cl01115
393115000111	Similar to CAD84104 (Q82XR1) Probable Mg(2+) chelatase family protein from Nitrosomonas europaea (500 aa). FASTA: opt: 1712 Z-score: 1729.4 E(): 1.8e-88 Smith-Waterman score: 1712; 54.582identity in 502 aa overlap. Contains two frameshifts after aa 44 and 442. Second frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0046
393115000112	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
393115000113	substrate binding site [chemical binding]; other site
393115000114	active site
393115000115	ribosome maturation protein RimP; Reviewed; Region: PRK00092
393115000116	The eukaryotic Sm and Sm-like (LSm) proteins associate with RNA to form the core domain of the ribonucleoprotein particles involved in a variety of RNA processing events including pre-mRNA splicing, telomere replication, and mRNA degradation.  Members of...; Region: Sm_like; cl00259
393115000117	The eukaryotic Sm and Sm-like (LSm) proteins associate with RNA to form the core domain of the ribonucleoprotein particles involved in a variety of RNA processing events including pre-mRNA splicing, telomere replication, and mRNA degradation.  Members of...; Region: Sm_like; cl00259
393115000118	Sm1 motif; other site
393115000119	D3 - B interaction site; other site
393115000120	D1 - D2 interaction site; other site
393115000121	Hfq - Hfq interaction site; other site
393115000122	RNA binding pocket [nucleotide binding]; other site
393115000123	Sm2 motif; other site
393115000124	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
393115000125	NusA N-terminal domain; Region: NusA_N; pfam08529
393115000126	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
393115000127	RNA binding site [nucleotide binding]; other site
393115000128	homodimer interface [polypeptide binding]; other site
393115000129	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cl00098
393115000130	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
393115000131	G-X-X-G motif; other site
393115000132	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
393115000133	translation initiation factor IF-2; Validated; Region: infB; PRK05306
393115000134	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
393115000135	translation initiation factor IF-2; Region: IF-2; TIGR00487
393115000136	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
393115000137	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
393115000138	G1 box; other site
393115000139	putative GEF interaction site [polypeptide binding]; other site
393115000140	GTP/Mg2+ binding site [chemical binding]; other site
393115000141	Switch I region; other site
393115000142	G2 box; other site
393115000143	G3 box; other site
393115000144	Switch II region; other site
393115000145	G4 box; other site
393115000146	G5 box; other site
393115000147	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
393115000148	Translation-initiation factor 2; Region: IF-2; pfam11987
393115000149	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
393115000150	Ribosome-binding factor A; Region: RBFA; cl00542
393115000151	histidyl-tRNA synthetase; Region: hisS; TIGR00442
393115000152	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: HisRS-like_core; cd00773
393115000153	dimer interface [polypeptide binding]; other site
393115000154	motif 1; other site
393115000155	active site
393115000156	motif 2; other site
393115000157	motif 3; other site
393115000158	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
393115000159	anticodon binding site; other site
393115000160	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000161	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
393115000162	putative substrate translocation pore; other site
393115000163	Predicted ATPase [General function prediction only]; Region: COG1485
393115000164	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
393115000165	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115000166	RNA binding surface [nucleotide binding]; other site
393115000167	PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and...; Region: PseudoU_synth_RluCD_like; cd02869
393115000168	active site
393115000169	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000170	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000171	putative substrate translocation pore; other site
393115000172	ATP synthase A chain; Region: ATP-synt_A; cl00413
393115000173	ATP synthase subunit C; Region: ATP-synt_C; cl00466
393115000174	Plant ATP synthase F0; Region: YMF19; cl07975
393115000175	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
393115000176	Plant ATP synthase F0; Region: YMF19; cl07975
393115000177	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
393115000178	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
393115000179	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; cl15275
393115000180	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
393115000181	beta subunit interaction interface [polypeptide binding]; other site
393115000182	Walker A motif; other site
393115000183	ATP binding site [chemical binding]; other site
393115000184	Walker B motif; other site
393115000185	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
393115000186	ATP synthase; Region: ATP-synt; cl00365
393115000187	F0F1 ATP synthase subunit gamma; Provisional; Region: PRK13422
393115000188	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
393115000189	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; cl15275
393115000190	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
393115000191	alpha subunit interaction interface [polypeptide binding]; other site
393115000192	Walker A motif; other site
393115000193	ATP binding site [chemical binding]; other site
393115000194	Walker B motif; other site
393115000195	inhibitor binding site; inhibition site
393115000196	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
393115000197	F0F1 ATP synthase subunit epsilon; Provisional; Region: atpC; PRK13452
393115000198	ATP synthase, Delta/Epsilon chain, beta-sandwich domain; Region: ATP-synt_DE_N; cl10033
393115000199	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
393115000200	GH18 domain of Chitinase D (ChiD).  ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins.  The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18; Region: GH18_chitinase_D-like; cd02871
393115000201	putative active site [active]
393115000202	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
393115000203	N-acetylglucosamine-binding protein A; Reviewed; Region: PRK13211
393115000204	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
393115000205	putative GSH binding site [chemical binding]; other site
393115000206	catalytic residues [active]
393115000207	superoxide dismutase; Provisional; Region: PRK10543
393115000208	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
393115000209	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
393115000210	muropeptide transporter; Validated; Region: ampG; PRK11010
393115000211	muropeptide transporter; Reviewed; Region: ampG; PRK11902
393115000212	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
393115000213	dimer interface [polypeptide binding]; other site
393115000214	Citrate synthase; Region: Citrate_synt; pfam00285
393115000215	active site
393115000216	citrylCoA binding site [chemical binding]; other site
393115000217	NADH binding [chemical binding]; other site
393115000218	cationic pore residues; other site
393115000219	oxalacetate/citrate binding site [chemical binding]; other site
393115000220	coenzyme A binding site [chemical binding]; other site
393115000221	catalytic triad [active]
393115000222	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
393115000223	Iron-sulfur protein interface; other site
393115000224	proximal quinone binding site [chemical binding]; other site
393115000225	SdhD (CybS) interface [polypeptide binding]; other site
393115000226	proximal heme binding site [chemical binding]; other site
393115000227	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
393115000228	SdhC subunit interface [polypeptide binding]; other site
393115000229	proximal heme binding site [chemical binding]; other site
393115000230	cardiolipin binding site; other site
393115000231	Iron-sulfur protein interface; other site
393115000232	proximal quinone binding site [chemical binding]; other site
393115000233	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
393115000234	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115000235	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
393115000236	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
393115000237	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
393115000238	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
393115000239	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
393115000240	TPP-binding site [chemical binding]; other site
393115000241	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
393115000242	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115000243	E3 interaction surface; other site
393115000244	lipoyl attachment site [posttranslational modification]; other site
393115000245	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
393115000246	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115000247	E3 interaction surface; other site
393115000248	lipoyl attachment site [posttranslational modification]; other site
393115000249	e3 binding domain; Region: E3_binding; pfam02817
393115000250	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; cl02008
393115000251	Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins [Nucleotide transport and metabolism]; Region: Apt; COG0503
393115000252	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115000253	active site
393115000254	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14320
393115000255	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
393115000256	active site
393115000257	substrate binding site [chemical binding]; other site
393115000258	metal binding site [ion binding]; metal-binding site
393115000259	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
393115000260	substrate binding site [chemical binding]; other site
393115000261	dimer interface [polypeptide binding]; other site
393115000262	catalytic triad [active]
393115000263	Preprotein translocase SecG subunit; Region: SecG; cl09123
393115000264	Similar to Q9CG05 LysR family transcriptional regulator from Lactococcus lactis (273 aa) .FASTA: opt: 186 Z-score: 225.0 E(): 0.00011 Smith-Waterman score: 186; 23.574 identity in 263 aa overlap. Contains an in-frame stop codon after aa 197 ORF ftt0082
393115000265	Peptidase propeptide and YPEB domain; Region: PepSY; cl15815
393115000266	Peptidase propeptide and YPEB domain; Region: PepSY; cl15815
393115000267	HemN family oxidoreductase; Provisional; Region: PRK05660
393115000268	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115000269	FeS/SAM binding site; other site
393115000270	HemN C-terminal domain; Region: HemN_C; pfam06969
393115000271	GtrA-like protein; Region: GtrA; cl00971
393115000272	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
393115000273	aconitate hydratase; Validated; Region: PRK09277
393115000274	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
393115000275	substrate binding site [chemical binding]; other site
393115000276	ligand binding site [chemical binding]; other site
393115000277	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
393115000278	substrate binding site [chemical binding]; other site
393115000279	pilus retraction protein PilT; Region: pilT_fam; TIGR01420
393115000280	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
393115000281	Walker A motif; other site
393115000282	ATP binding site [chemical binding]; other site
393115000283	Walker B motif; other site
393115000284	Similar to Q9HVD5 Hypothetical protein PA4657 from Pseudomonas aeruginosa (327 aa). FASTA: 552 Z-score: 636.7 E(): 1.3e-27 Smith-Waterman score: 552; 28.395 identity in 324 aa overlap. Contains 2 frameshifts after aa 73 and 158 ORF ftt0089c
393115000285	Protein of unknown function (DUF3429); Region: DUF3429; pfam11911
393115000286	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
393115000287	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
393115000288	Similar to Q92IY2 Cytochrome d ubiquinol oxidase subunit I from Rickettsia conorii (456 aa). FASTA: opt: 1445 Z-score: 1673.2 E(): 2.4e-85 Smith-Waterman score: 1443; 49.083identity in 436 aa overlap. Contains an in-frame stop codon after aa 80
393115000289	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
393115000290	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
393115000291	putative NAD(P) binding site [chemical binding]; other site
393115000292	putative active site [active]
393115000293	sensor protein QseC; Provisional; Region: PRK10337
393115000294	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
393115000295	dimer interface [polypeptide binding]; other site
393115000296	phosphorylation site [posttranslational modification]
393115000297	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115000298	ATP binding site [chemical binding]; other site
393115000299	Mg2+ binding site [ion binding]; other site
393115000300	G-X-G motif; other site
393115000301	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115000302	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000303	Integrase core domain; Region: rve; cl01316
393115000304	Transposase domain (DUF772); Region: DUF772; cl15789
393115000305	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115000306	Transposase domain (DUF772); Region: DUF772; cl15789
393115000307	Similar to Q9K0L1 IS1016C2 transposase from Neisseria meningitidis serogroup B strain MC58 (222 aa). FASTA: opt: 368 Z-score: 482.6 E(): 5e-19 Smith-Waterman score: 368; 49.123 identity in 114 aa overlap. This CDS has no start codon due to disruption by the insertion of an ISFtu1 element at the N-terminal end Identical to carboxy terminus of FTF1053c and FTF1792c ORF ftt0100
393115000308	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
393115000309	dimer interface [polypeptide binding]; other site
393115000310	catalytic triad [active]
393115000311	Similar to NP_927686.1| Transposase, IS982 family from Photorhabdus luminescens subsp laumondii TTO1. Score = 170 bits (431),Expect = 2e-41 Identities = 95/258 (36),Positives = 146/258 (56), Gaps = 5/258 (1). Contains an in-frame stop codon after aa 87 and frameshifts after aa 138 and 216 ORF ftt0102
393115000312	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000313	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
393115000314	multidrug efflux protein; Reviewed; Region: PRK09579
393115000315	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
393115000316	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115000317	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115000318	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
393115000319	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13296
393115000320	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
393115000321	active site
393115000322	NTP binding site [chemical binding]; other site
393115000323	metal binding triad [ion binding]; metal-binding site
393115000324	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
393115000325	lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203
393115000326	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
393115000327	MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins.  ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic...; Region: ABCC_MsbA; cd03251
393115000328	Walker A/P-loop; other site
393115000329	ATP binding site [chemical binding]; other site
393115000330	Q-loop/lid; other site
393115000331	ABC transporter signature motif; other site
393115000332	Walker B; other site
393115000333	D-loop; other site
393115000334	H-loop/switch region; other site
393115000335	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; cl03652
393115000336	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
393115000337	DNA polymerase I; Provisional; Region: PRK05755
393115000338	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
393115000339	active site
393115000340	metal binding site 1 [ion binding]; metal-binding site
393115000341	putative 5' ssDNA interaction site; other site
393115000342	metal binding site 3; metal-binding site
393115000343	metal binding site 2 [ion binding]; metal-binding site
393115000344	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
393115000345	putative DNA binding site [nucleotide binding]; other site
393115000346	putative metal binding site [ion binding]; other site
393115000347	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
393115000348	active site
393115000349	catalytic site [active]
393115000350	substrate binding site [chemical binding]; other site
393115000351	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
393115000352	active site
393115000353	DNA binding site [nucleotide binding]
393115000354	catalytic site [active]
393115000355	Type III pantothenate kinase; Region: Pan_kinase; cl09130
393115000356	Sulfatase; Region: Sulfatase; cl10460
393115000357	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
393115000358	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
393115000359	intersubunit interface [polypeptide binding]; other site
393115000360	active site
393115000361	catalytic residue [active]
393115000362	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
393115000363	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
393115000364	Nucleoside recognition; Region: Gate; cl00486
393115000365	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
393115000366	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
393115000367	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
393115000368	Nucleoside recognition; Region: Gate; cl00486
393115000369	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
393115000370	thymidylate kinase; Validated; Region: tmk; PRK00698
393115000371	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
393115000372	TMP-binding site; other site
393115000373	ATP-binding site [chemical binding]; other site
393115000374	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
393115000375	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
393115000376	G1 box; other site
393115000377	putative GEF interaction site [polypeptide binding]; other site
393115000378	GTP/Mg2+ binding site [chemical binding]; other site
393115000379	Switch I region; other site
393115000380	G2 box; other site
393115000381	G3 box; other site
393115000382	Switch II region; other site
393115000383	G4 box; other site
393115000384	G5 box; other site
393115000385	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
393115000386	Lysin domain, found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function; Region: LysM; cl00107
393115000387	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
393115000388	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
393115000389	SRP54-type protein, helical bundle domain; Region: SRP54_N; cl03758
393115000390	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
393115000391	GTP binding site [chemical binding]; other site
393115000392	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
393115000393	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115000394	Family description; Region: UvrD_C_2; cl15862
393115000395	Similar to OPPA_HAEIN (P71370) Periplasmic oligopeptide-binding protein (precursor) from Haemophilus influenzae (541 aa). FASTA: opt: 924 Z-score: 1112.1 E(): 4.7e-54 Smith-Waterman score: 924; 34.490identity in 461 aa overlap oligopeptide transporter, subunit A, ABC transporter, periplasmic protein
393115000396	Similar to Q9CJT2 (Q9CJT2) OppB from Pasteurella multicoda (306 aa) FASTA: opt: 953 Z-score: 1065.0 E(): 2e-51 Smith-Waterman score: 953; 46.645 identity in 313 aa overlap. Contains a frameshift after aa 89
393115000397	Similar to Q87MY7 Oligopeptide ABC transporter,permease frim Vibrio parahaemolyticus (300 aa). FASTA: opt: 1042 Z-score: 1224.8 E(): 2.3e-60 Smith-Waterman score: 1042; 52.857 identity in 280 aa overlap. Contains no start codon and a frameshift after aa 74
393115000398	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
393115000399	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
393115000400	Walker A/P-loop; other site
393115000401	ATP binding site [chemical binding]; other site
393115000402	Q-loop/lid; other site
393115000403	ABC transporter signature motif; other site
393115000404	Walker B; other site
393115000405	D-loop; other site
393115000406	H-loop/switch region; other site
393115000407	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
393115000408	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
393115000409	The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE).  The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane...; Region: ABC_NikE_OppD_transporters; cd03257
393115000410	Walker A/P-loop; other site
393115000411	ATP binding site [chemical binding]; other site
393115000412	Q-loop/lid; other site
393115000413	ABC transporter signature motif; other site
393115000414	Walker B; other site
393115000415	D-loop; other site
393115000416	H-loop/switch region; other site
393115000417	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
393115000418	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000419	putative substrate translocation pore; other site
393115000420	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000421	putative substrate translocation pore; other site
393115000422	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000423	glycerol kinase; Provisional; Region: glpK; PRK00047
393115000424	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
393115000425	N- and C-terminal domain interface [polypeptide binding]; other site
393115000426	active site
393115000427	MgATP binding site [chemical binding]; other site
393115000428	catalytic site [active]
393115000429	metal binding site [ion binding]; metal-binding site
393115000430	glycerol binding site [chemical binding]; other site
393115000431	homotetramer interface [polypeptide binding]; other site
393115000432	homodimer interface [polypeptide binding]; other site
393115000433	FBP binding site [chemical binding]; other site
393115000434	protein IIAGlc interface [polypeptide binding]; other site
393115000435	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000436	Integrase core domain; Region: rve; cl01316
393115000437	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
393115000438	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
393115000439	amphipathic channel; other site
393115000440	Asn-Pro-Ala signature motifs; other site
393115000441	Similar to YGGB_EDWIC (O52401) Hypothetical UPF0003 protein in iciA-fba intergenic region from Edwardsiella ictaluri (286 aa). FASTA: opt: 317 Z-score: 385.5 E(): 1.4e-13 Smith-Waterman score: 317; 33.121 identity in 157 aa overlap. Truncation of C-terminal according to FASTA hits ORF ftt0135
393115000442	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115000443	Family description; Region: UvrD_C_2; cl15862
393115000444	elongation factor Tu; Reviewed; Region: PRK00049
393115000445	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
393115000446	G1 box; other site
393115000447	GEF interaction site [polypeptide binding]; other site
393115000448	GTP/Mg2+ binding site [chemical binding]; other site
393115000449	Switch I region; other site
393115000450	G2 box; other site
393115000451	G3 box; other site
393115000452	Switch II region; other site
393115000453	G4 box; other site
393115000454	G5 box; other site
393115000455	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
393115000456	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
393115000457	Antibiotic Binding Site [chemical binding]; other site
393115000458	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
393115000459	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
393115000460	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
393115000461	putative homodimer interface [polypeptide binding]; other site
393115000462	KOW motif; Region: KOW; cl00354
393115000463	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
393115000464	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
393115000465	23S rRNA interface [nucleotide binding]; other site
393115000466	L7/L12 interface [polypeptide binding]; other site
393115000467	putative thiostrepton binding site; other site
393115000468	L25 interface [polypeptide binding]; other site
393115000469	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
393115000470	mRNA/rRNA interface [nucleotide binding]; other site
393115000471	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
393115000472	23S rRNA interface [nucleotide binding]; other site
393115000473	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
393115000474	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
393115000475	core dimer interface [polypeptide binding]; other site
393115000476	peripheral dimer interface [polypeptide binding]; other site
393115000477	L10 interface [polypeptide binding]; other site
393115000478	L11 interface [polypeptide binding]; other site
393115000479	putative EF-Tu interaction site [polypeptide binding]; other site
393115000480	putative EF-G interaction site [polypeptide binding]; other site
393115000481	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl04593
393115000482	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
393115000483	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
393115000484	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
393115000485	RPB12 interaction site [polypeptide binding]; other site
393115000486	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl04593
393115000487	RPB11 interaction site [polypeptide binding]; other site
393115000488	RPB12 interaction site [polypeptide binding]; other site
393115000489	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
393115000490	RPB3 interaction site [polypeptide binding]; other site
393115000491	RPB1 interaction site [polypeptide binding]; other site
393115000492	RPB11 interaction site [polypeptide binding]; other site
393115000493	RPB10 interaction site [polypeptide binding]; other site
393115000494	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
393115000495	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
393115000496	RNA polymerase Rpb1, domain 2; Region: RNA_pol_Rpb1_2; cl11591
393115000497	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
393115000498	DNA-directed RNA polymerase, beta'' subunit; Region: rpoC2_cyan; TIGR02388
393115000499	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
393115000500	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
393115000501	cleft; other site
393115000502	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
393115000503	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
393115000504	DNA-directed RNA polymerase, beta' subunit, predominant form; Region: rpoC_TIGR; TIGR02386
393115000505	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
393115000506	DNA binding site [nucleotide binding]
393115000507	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
393115000508	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
393115000509	UGMP family protein; Validated; Region: PRK09604
393115000510	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl14000
393115000511	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115000512	Di-iron ligands [ion binding]; other site
393115000513	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115000514	S-adenosylmethionine synthetase; Validated; Region: PRK05250
393115000515	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
393115000516	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
393115000517	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
393115000518	Ribosomal protein S16; Region: Ribosomal_S16; cl00368
393115000519	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14591
393115000520	RimM N-terminal domain; Region: RimM; pfam01782
393115000521	Photosynthetic reaction center (RC) complex, subunit H;  RC is an integral membrane protein-pigment complex which catalyzes light-induced reduction of ubiquinone to ubiquinol, generating a transmembrane electrochemical gradient of protons used to produce...; Region: PRCH; cl09959
393115000522	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
393115000523	Ribosomal protein L19; Region: Ribosomal_L19; cl00406
393115000524	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
393115000525	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
393115000526	DNA binding site [nucleotide binding]
393115000527	Int/Topo IB signature motif; other site
393115000528	active site
393115000529	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; cl14733
393115000530	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; cl15773
393115000531	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115000532	Glucosyl transferase GtrII; Region: Glucos_trans_II; cl10304
393115000533	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
393115000534	putative active site [active]
393115000535	Ap4A binding site [chemical binding]; other site
393115000536	nudix motif; other site
393115000537	putative metal binding site [ion binding]; other site
393115000538	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
393115000539	active site
393115000540	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
393115000541	amidase catalytic site [active]
393115000542	Zn binding residues [ion binding]; other site
393115000543	substrate binding site [chemical binding]; other site
393115000544	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
393115000545	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
393115000546	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
393115000547	anchoring element; other site
393115000548	dimer interface [polypeptide binding]; other site
393115000549	ATP binding site [chemical binding]; other site
393115000550	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
393115000551	active site
393115000552	metal binding site [ion binding]; metal-binding site
393115000553	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
393115000554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000555	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
393115000556	putative substrate translocation pore; other site
393115000557	outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300
393115000558	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
393115000559	Trp docking motif [polypeptide binding]; other site
393115000560	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
393115000561	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
393115000562	TPR motif; other site
393115000563	binding surface
393115000564	glutamyl-tRNA reductase; Provisional; Region: PRK13940
393115000565	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
393115000566	tRNA; other site
393115000567	putative tRNA binding site [nucleotide binding]; other site
393115000568	putative NADP binding site [chemical binding]; other site
393115000569	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
393115000570	peptide chain release factor 1; Validated; Region: prfA; PRK00591
393115000571	RF-1 domain; Region: RF-1; cl02875
393115000572	RF-1 domain; Region: RF-1; cl02875
393115000573	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
393115000574	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115000575	Similar to YCA8_PSEPK (Q88DL7) Hypothetical UPF0247 protein PP4808 from Pseudomonas putida (155 aa). FASTA: opt: 433 Z-score: 550.0 E(): 9.6e-23 Smith-Waterman score: 433; 42.254 identity in 142 aa overlap. This CDS lacks a start codon due to the insertion of an ISFtu1 element at the N-terminal ORF ftt0170c
393115000576	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000577	Integrase core domain; Region: rve; cl01316
393115000578	ORF ftt0172
393115000579	Similar to Q87J48 Hypothetical protein from Vibro parahaemolyticus (305 aa). FASTA: opt: 1031 Z-score: 1265.1 E(): 1.3e-62 Smith-Waterman score: 1031; 52.365 identity in 296 aa overlap. Contains a frameshift after aa 227 and an in-frame stop aa at 267 ORF ftt0173
393115000580	YGGT family; Region: YGGT; cl00508
393115000581	YGGT family; Region: YGGT; cl00508
393115000582	NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively.  ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars; Region: ABC_NrtD_SsuB_transporters; cd03293
393115000583	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
393115000584	Walker A/P-loop; other site
393115000585	ATP binding site [chemical binding]; other site
393115000586	Q-loop/lid; other site
393115000587	ABC transporter signature motif; other site
393115000588	Walker B; other site
393115000589	D-loop; other site
393115000590	H-loop/switch region; other site
393115000591	Similar to Q836Q4 ABC transporter, permease protein from Enterococcus faecalis (585 aa). FASTA: opt: 1474 Z-score: 1670.8 E(): 3.3e-85 Smith-Waterman score: 1476; 39.519identity in 582 aa overlap. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0176c
393115000592	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
393115000593	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
393115000594	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
393115000595	Coenzyme A binding pocket [chemical binding]; other site
393115000596	RimK-like ATPgrasp N-terminal domain; Region: RLAN; pfam14401
393115000597	alpha-L-glutamate ligases, RimK family; Region: rimK_fam; TIGR00768
393115000598	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115000599	Similar to CAD86320 (Q82SD2) DNA internalization-related competence protein ComEC/Rec2 from Nitrosomonas europaea (799 aa). FASTA: opt: 531 Z-score: 549.2 E(): 9.6e-23 Smith-Waterman score: 554; 23.668 identity in 638 aa overlap. Contains a frameshift after aa 225 ORF ftt0179
393115000600	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
393115000601	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
393115000602	putative acyl-acceptor binding pocket; other site
393115000603	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
393115000604	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
393115000605	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
393115000606	RNA binding site [nucleotide binding]; other site
393115000607	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
393115000608	RNA binding site [nucleotide binding]; other site
393115000609	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists of...; Region: S1_RPS1_repeat_ec3; cd05688
393115000610	RNA binding site [nucleotide binding]; other site
393115000611	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115000612	RNA binding site [nucleotide binding]; other site
393115000613	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists of...; Region: S1_RPS1_repeat_ec5; cd05690
393115000614	RNA binding site [nucleotide binding]; other site
393115000615	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists of...; Region: S1_RPS1_repeat_ec6; cd05691
393115000616	RNA binding site [nucleotide binding]; other site
393115000617	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
393115000618	nucleoside/Zn binding site; other site
393115000619	dimer interface [polypeptide binding]; other site
393115000620	catalytic motif [active]
393115000621	D-alanyl-alanine synthetase A; Provisional; Region: PRK14569
393115000622	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
393115000623	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115000624	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
393115000625	Cell division protein FtsQ; Region: FtsQ; pfam03799
393115000626	cell division protein FtsA; Region: ftsA; TIGR01174
393115000627	Cell division protein FtsA; Region: FtsA; cl11496
393115000628	Cell division protein FtsA; Region: FtsA; cl11496
393115000629	cell division protein FtsZ; Validated; Region: PRK09330
393115000630	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
393115000631	nucleotide binding site [chemical binding]; other site
393115000632	SulA interaction site; other site
393115000633	UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]; Region: LpxC; cl00512
393115000634	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
393115000635	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14957
393115000636	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115000637	Walker A motif; other site
393115000638	ATP binding site [chemical binding]; other site
393115000639	Walker B motif; other site
393115000640	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115000641	arginine finger; other site
393115000642	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
393115000643	peptide chain release factor 2; Provisional; Region: PRK07342
393115000644	RF-1 domain; Region: RF-1; cl02875
393115000645	RF-1 domain; Region: RF-1; cl02875
393115000646	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
393115000647	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
393115000648	dimer interface [polypeptide binding]; other site
393115000649	putative anticodon binding site; other site
393115000650	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
393115000651	motif 1; other site
393115000652	active site
393115000653	motif 2; other site
393115000654	motif 3; other site
393115000655	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
393115000656	CAAX protease self-immunity; Region: Abi; cl00558
393115000657	Eps15 homology domain; Region: EH; smart00027
393115000658	Glutaminase; Region: Glutaminase; cl00907
393115000659	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
393115000660	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
393115000661	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
393115000662	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
393115000663	glutamine synthetase; Region: PLN02284
393115000664	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
393115000665	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
393115000666	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
393115000667	Lipocalin / cytosolic fatty-acid binding protein family; Region: Lipocalin; cl01150
393115000668	Similar to Q87MQ6 Putative HAAAP family transport protein from Vibrio parahaemolyticus (441 aa). FASTA: opt: 848 Z-score: 1002.0 E(): 5.8e-48 Smith-Waterman score: 848; 36.292 identity in 383 aa overlap. CDS is interrupted by an ISFtu2 element. It also contains a frameshift after aa 190 and an in-frame stop codon after aa 401 ORF ftt0201
393115000669	Transposase domain (DUF772); Region: DUF772; cl15789
393115000670	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115000671	Transposase domain (DUF772); Region: DUF772; cl15789
393115000672	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
393115000673	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
393115000674	purine monophosphate binding site [chemical binding]; other site
393115000675	dimer interface [polypeptide binding]; other site
393115000676	putative catalytic residues [active]
393115000677	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
393115000678	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
393115000679	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
393115000680	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
393115000681	GDP-binding site [chemical binding]; other site
393115000682	ACT binding site; other site
393115000683	IMP binding site; other site
393115000684	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115000685	active site
393115000686	Similar to AAO90632 (Q83CJ6) Dienelactone hydrolase family protein from Coxiella burnetti (237 aa). FASTA: opt: 718 Z-score: 895.1 E(): 5.2e-42 Smith-Waterman score: 718; 46.809 identity in 235 aa overlap. Contains a frameshift after aa 54. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0206c
393115000687	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
393115000688	dimer interface [polypeptide binding]; other site
393115000689	putative PBP binding regions; other site
393115000690	ABC-ATPase subunit  interface; other site
393115000691	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
393115000692	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115000693	Walker A/P-loop; other site
393115000694	ATP binding site [chemical binding]; other site
393115000695	Q-loop/lid; other site
393115000696	ABC transporter signature motif; other site
393115000697	Walker B; other site
393115000698	D-loop; other site
393115000699	H-loop/switch region; other site
393115000700	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
393115000701	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
393115000702	intersubunit interface [polypeptide binding]; other site
393115000703	Similar to AAO90981 (Q83BM0) Major facilitator family transporter from Coxiella burnetti (428 aa). FASTA: opt: 399 Z-score: 467.4 E(): 3.5e-18 Smith-Waterman score: 502; 25.307 identity in 407 aa overlap. Contains several stop codons ORF ftt0210c
393115000704	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
393115000705	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
393115000706	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
393115000707	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
393115000708	primosome assembly protein PriA; Validated; Region: PRK05580
393115000709	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115000710	ATP binding site [chemical binding]; other site
393115000711	putative Mg++ binding site [ion binding]; other site
393115000712	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115000713	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000714	Integrase core domain; Region: rve; cl01316
393115000715	hypothetical protein, pseudogene. This CDS lacks a start codon due to an interruption by an ISFtu1 element at the N-terminal end ORF ftt0217
393115000716	Similar to Q9I539 Cytochrome b561 from Pseudomonas aeruginosa (182 aa). FASTA: opt: 265 Z-score: 332.5 E(): 1.3e-10 Smith-Waterman score: 265; 30.357 identity in 168 aa overlap. Contains an in-frame stop codon after aa 50 ORF ftt0218c
393115000717	Phosphate transporter family; Region: PHO4; cl00396
393115000718	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
393115000719	Phosphoesterase family; Region: Phosphoesterase; cl15450
393115000720	Allophanate hydrolase subunit 2; Region: AHS2; cl00865
393115000721	LamB/YcsF family; Region: LamB_YcsF; cl00664
393115000722	Similar to Q8NW92 Hypothetical protein MW1559 from Staphylococcus aureus (244 aa). FASTA: opt: 350 Z-score: 439.8 E(): 1.2e-16 Smith-Waterman score: 350; 38.012 identity in 171 aa overlap. Contains an in-frame stop codon after aa 14 ORF ftt0224c
393115000723	Similar to AAO91543 (Q83A52) Major facilitator family transporter from Coxiella burnetti (443 aa). FASTA: opt: 546 Z-score: 623.3 E(): 7.3e-27 Smith-Waterman score: 546; 28.693 identity in 352 aa overlap. This CDS has no start codon caused by insertion of an ISFtu1 element at N-terminal ORF ftt0225c
393115000724	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000725	Integrase core domain; Region: rve; cl01316
393115000726	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
393115000727	putative active site [active]
393115000728	putative substrate binding site [chemical binding]; other site
393115000729	catalytic site [active]
393115000730	dimer interface [polypeptide binding]; other site
393115000731	elongation factor P; Validated; Region: PRK00529
393115000732	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
393115000733	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
393115000734	RNA binding site [nucleotide binding]; other site
393115000735	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
393115000736	RNA binding site [nucleotide binding]; other site
393115000737	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
393115000738	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
393115000739	putative acyl-acceptor binding pocket; other site
393115000740	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
393115000741	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
393115000742	putative acyl-acceptor binding pocket; other site
393115000743	membrane protein insertase; Provisional; Region: PRK01318
393115000744	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
393115000745	Haemolytic domain; Region: Haemolytic; cl00506
393115000746	Ribonuclease P; Region: Ribonuclease_P; cl00457
393115000747	Ribosomal protein L34; Region: Ribosomal_L34; cl00370
393115000748	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
393115000749	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
393115000750	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
393115000751	shikimate binding site; other site
393115000752	NAD(P) binding site [chemical binding]; other site
393115000753	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
393115000754	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
393115000755	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115000756	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115000757	Predicted methyltransferases [General function prediction only]; Region: COG0313
393115000758	Precorrin-3B methylase [Coenzyme metabolism]; Region: CobJ; cl00304
393115000759	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
393115000760	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115000761	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
393115000762	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
393115000763	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
393115000764	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204
393115000765	PLD-like domain; Region: PLDc_2; pfam13091
393115000766	putative homodimer interface [polypeptide binding]; other site
393115000767	putative active site [active]
393115000768	catalytic site [active]
393115000769	DEAD-like helicases superfamily; Region: DEXDc; smart00487
393115000770	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115000771	ATP binding site [chemical binding]; other site
393115000772	putative Mg++ binding site [ion binding]; other site
393115000773	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115000774	nucleotide binding region [chemical binding]; other site
393115000775	ATP-binding site [chemical binding]; other site
393115000776	Domain of unknown function (DUF3427); Region: DUF3427; pfam11907
393115000777	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
393115000778	Ligand Binding Site [chemical binding]; other site
393115000779	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
393115000780	Ligand Binding Site [chemical binding]; other site
393115000781	hypothetical protein, pseudogene; This CDS lacks a start codon due to an interruption by an ISFtu1 element at the N-terminal end ORF ftt0246c
393115000782	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000783	Integrase core domain; Region: rve; cl01316
393115000784	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
393115000785	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
393115000786	G1 box; other site
393115000787	GTP/Mg2+ binding site [chemical binding]; other site
393115000788	Switch I region; other site
393115000789	G2 box; other site
393115000790	G3 box; other site
393115000791	Switch II region; other site
393115000792	G4 box; other site
393115000793	G5 box; other site
393115000794	Nucleoside recognition; Region: Gate; cl00486
393115000795	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
393115000796	Nucleoside recognition; Region: Gate; cl00486
393115000797	pyruvate phosphate dikinase; Provisional; Region: PRK09279
393115000798	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
393115000799	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
393115000800	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; cl01586
393115000801	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl09155
393115000802	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
393115000803	homodimer interface [polypeptide binding]; other site
393115000804	substrate-cofactor binding pocket; other site
393115000805	catalytic residue [active]
393115000806	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
393115000807	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
393115000808	active site
393115000809	catalytic residues [active]
393115000810	metal binding site [ion binding]; metal-binding site
393115000811	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000812	Integrase core domain; Region: rve; cl01316
393115000813	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
393115000814	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
393115000815	RNB domain; Region: RNB; pfam00773
393115000816	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
393115000817	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
393115000818	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
393115000819	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
393115000820	domain interfaces; other site
393115000821	active site
393115000822	CrcB-like protein; Region: CRCB; cl09114
393115000823	Zinc-finger domain; Region: zf-CHCC; cl01821
393115000824	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
393115000825	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115000826	dimer interface [polypeptide binding]; other site
393115000827	conserved gate region; other site
393115000828	putative PBP binding loops; other site
393115000829	ABC-ATPase subunit interface; other site
393115000830	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
393115000831	NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively.  ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars; Region: ABC_NrtD_SsuB_transporters; cd03293
393115000832	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
393115000833	Walker A/P-loop; other site
393115000834	ATP binding site [chemical binding]; other site
393115000835	Q-loop/lid; other site
393115000836	ABC transporter signature motif; other site
393115000837	Walker B; other site
393115000838	D-loop; other site
393115000839	H-loop/switch region; other site
393115000840	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; cl15413
393115000841	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115000842	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
393115000843	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
393115000844	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115000845	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
393115000846	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
393115000847	trimer interface [polypeptide binding]; other site
393115000848	putative metal binding site [ion binding]; other site
393115000849	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
393115000850	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
393115000851	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
393115000852	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115000853	Integrase core domain; Region: rve; cl01316
393115000854	Similar to Q8CN60 Bicyclomycin resistance protein TcaB from Staphylococcus epidermidis (400 aa). FASTA: opt: 373 Z-score: 410.0 E(): 6.1e-15 Smith-Waterman score: 373; 29.412 identity in 238 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt0275c
393115000855	Similar to Q89LI3 Probable cyclohexadienyl dehydratase precusor from Bradyrhizobium japonicum (260 aa). FASTA: opt: 349 Z-score: 407.8 E(): 7.3e-15 Smith-Waterman score: 349; 30.841 identity in 214 aa overlap. Contains a frameshift after aa 73 ORF ftt0276c
393115000856	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
393115000857	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
393115000858	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
393115000859	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
393115000860	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
393115000861	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000862	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000863	putative substrate translocation pore; other site
393115000864	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
393115000865	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; cl11412
393115000866	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
393115000867	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
393115000868	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
393115000869	D-pathway; other site
393115000870	Putative ubiquinol binding site [chemical binding]; other site
393115000871	Low-spin heme (heme b) binding site [chemical binding]; other site
393115000872	Putative water exit pathway; other site
393115000873	Binuclear center (heme o3/CuB) [ion binding]; other site
393115000874	K-pathway; other site
393115000875	Putative proton exit pathway; other site
393115000876	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
393115000877	Subunit I/III interface [polypeptide binding]; other site
393115000878	Subunit III/IV interface [polypeptide binding]; other site
393115000879	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; cl01204
393115000880	UbiA prenyltransferase family; Region: UbiA; cl00337
393115000881	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
393115000882	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
393115000883	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
393115000884	trimer interface [polypeptide binding]; other site
393115000885	active site
393115000886	UDP-GlcNAc binding site [chemical binding]; other site
393115000887	lipid binding site [chemical binding]; lipid-binding site
393115000888	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1244
393115000889	pyridoxamine kinase; Validated; Region: PRK05756
393115000890	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
393115000891	dimer interface [polypeptide binding]; other site
393115000892	pyridoxal binding site [chemical binding]; other site
393115000893	ATP binding site [chemical binding]; other site
393115000894	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115000895	MoxR-like ATPases [General function prediction only]; Region: COG0714
393115000896	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115000897	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
393115000898	Domain of unknown function (DUF4381); Region: DUF4381; pfam14316
393115000899	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
393115000900	metal ion-dependent adhesion site (MIDAS); other site
393115000901	Similar to Q8ECP1 TPR domain protein from Shewanella oneidensis (679 aa). FASTA: opt: 1173 Z-score: 1061.1 E(): 3e-51 Smith-Waterman score: 1179; 32.305 identity in 616 aa overlap. Contains a frameshift after aa 332 This protein also has a match to Q93EJ8 Hypothetical 27.1 kDa protein from Francisella tularensis (231 aa). FASTA: opt: 1485 Z-score: 1347.0 E(): 3.5e-67 Smith-Waterman score: 1485; 96.943 identity in 229 aa overlap. This protein was originally incorrectly sequenced (Pubmed: 11526142) (direct communication with authors). C-terminal contains multiple 9bp tandem repeats ORF ftt0294
393115000902	Oxygen tolerance; Region: BatD; pfam13584
393115000903	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
393115000904	putative substrate binding pocket [chemical binding]; other site
393115000905	AC domain interface; other site
393115000906	catalytic triad [active]
393115000907	AB domain interface; other site
393115000908	interchain disulfide; other site
393115000909	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; cl01106
393115000910	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
393115000911	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
393115000912	HIGH motif; other site
393115000913	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
393115000914	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
393115000915	active site
393115000916	KMSKS motif; other site
393115000917	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
393115000918	tRNA binding surface [nucleotide binding]; other site
393115000919	anticodon binding site; other site
393115000920	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
393115000921	1-deoxy-D-xylulose-5-phosphate synthase; Region: PLN02225
393115000922	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
393115000923	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108
393115000924	phosphate binding site [ion binding]; other site
393115000925	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
393115000926	dimer interface [polypeptide binding]; other site
393115000927	FMN binding site [chemical binding]; other site
393115000928	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690
393115000929	nudix motif; other site
393115000930	fumarate hydratase; Reviewed; Region: fumC; PRK00485
393115000931	Class II fumarases; Region: Fumarase_classII; cd01362
393115000932	active site
393115000933	tetramer interface [polypeptide binding]; other site
393115000934	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
393115000935	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
393115000936	HIGH motif; other site
393115000937	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
393115000938	active site
393115000939	KMSKS motif; other site
393115000940	Transposase domain (DUF772); Region: DUF772; cl15789
393115000941	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115000942	Transposase domain (DUF772); Region: DUF772; cl15789
393115000943	amino acid transporter; Region: 2A0306; TIGR00909
393115000944	Amidinotransferase; Region: Amidinotransf; cl12043
393115000945	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
393115000946	folate binding site [chemical binding]; other site
393115000947	NADP+ binding site [chemical binding]; other site
393115000948	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
393115000949	rRNA interaction site [nucleotide binding]; other site
393115000950	S8 interaction site; other site
393115000951	putative laminin-1 binding site; other site
393115000952	elongation factor Ts; Provisional; Region: tsf; PRK09377
393115000953	Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153
393115000954	Elongation factor TS; Region: EF_TS; pfam00889
393115000955	Elongation factor TS; Region: EF_TS; pfam00889
393115000956	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
393115000957	putative nucleotide binding site [chemical binding]; other site
393115000958	uridine monophosphate binding site [chemical binding]; other site
393115000959	homohexameric interface [polypeptide binding]; other site
393115000960	ribosome recycling factor; Reviewed; Region: frr; PRK00083
393115000961	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are 'recycled' and ready for another round of...; Region: RRF; cd00520
393115000962	hinge region; other site
393115000963	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
393115000964	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
393115000965	catalytic residue [active]
393115000966	putative FPP diphosphate  binding site; other site
393115000967	putative FPP binding hydrophobic cleft; other site
393115000968	dimer interface [polypeptide binding]; other site
393115000969	putative IPP diphosphate binding site; other site
393115000970	Cytidylyltransferase family; Region: CTP_transf_1; cl00347
393115000971	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
393115000972	trimer interface [polypeptide binding]; other site
393115000973	active site
393115000974	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
393115000975	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
393115000976	S17 interaction site [polypeptide binding]; other site
393115000977	S8 interaction site; other site
393115000978	16S rRNA interaction site [nucleotide binding]; other site
393115000979	streptomycin interaction site [chemical binding]; other site
393115000980	23S rRNA interaction site [nucleotide binding]; other site
393115000981	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
393115000982	Ribosomal protein S7p/S5e; Region: Ribosomal_S7; cl00313
393115000983	elongation factor G; Reviewed; Region: PRK00007
393115000984	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
393115000985	G1 box; other site
393115000986	putative GEF interaction site [polypeptide binding]; other site
393115000987	GTP/Mg2+ binding site [chemical binding]; other site
393115000988	Switch I region; other site
393115000989	G2 box; other site
393115000990	G3 box; other site
393115000991	Switch II region; other site
393115000992	G4 box; other site
393115000993	G5 box; other site
393115000994	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
393115000995	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
393115000996	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
393115000997	Ribosomal protein S10p/S20e; Region: Ribosomal_S10; cl00314
393115000998	Ribosomal protein L3; Region: Ribosomal_L3; cl00324
393115000999	Ribosomal protein L4/L1 family; Region: Ribosomal_L4; cl00325
393115001000	Ribosomal protein L23; Region: Ribosomal_L23; cl00326
393115001001	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
393115001002	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
393115001003	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
393115001004	Ribosomal protein S19; Region: Ribosomal_S19; cl00350
393115001005	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
393115001006	putative translocon binding site; other site
393115001007	protein-rRNA interface [nucleotide binding]; other site
393115001008	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
393115001009	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
393115001010	G-X-X-G motif; other site
393115001011	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
393115001012	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
393115001013	23S rRNA interface [nucleotide binding]; other site
393115001014	5S rRNA interface [nucleotide binding]; other site
393115001015	putative antibiotic binding site [chemical binding]; other site
393115001016	L25 interface [polypeptide binding]; other site
393115001017	L27 interface [polypeptide binding]; other site
393115001018	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
393115001019	23S rRNA interface [nucleotide binding]; other site
393115001020	putative translocon interaction site; other site
393115001021	signal recognition particle (SRP54) interaction site; other site
393115001022	L23 interface [polypeptide binding]; other site
393115001023	trigger factor interaction site; other site
393115001024	Ribosomal protein S17; Region: Ribosomal_S17; cl00351
393115001025	Ribosomal protein L14p/L23e; Region: Ribosomal_L14; cl00328
393115001026	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
393115001027	KOW motif; Region: KOW; cl00354
393115001028	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
393115001029	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
393115001030	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
393115001031	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
393115001032	Ribosomal protein S8; Region: Ribosomal_S8; cl00330
393115001033	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
393115001034	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
393115001035	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
393115001036	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
393115001037	23S rRNA interface [nucleotide binding]; other site
393115001038	L21e interface [polypeptide binding]; other site
393115001039	5S rRNA interface [nucleotide binding]; other site
393115001040	L27 interface [polypeptide binding]; other site
393115001041	L5 interface [polypeptide binding]; other site
393115001042	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
393115001043	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
393115001044	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
393115001045	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
393115001046	23S rRNA binding site [nucleotide binding]; other site
393115001047	Ribosomal protein L18e/L15; Region: Ribosomal_L18e; cl12022
393115001048	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
393115001049	SecY translocase; Region: SecY; pfam00344
393115001050	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
393115001051	Ribosomal protein S13/S18; Region: Ribosomal_S13; cl00331
393115001052	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
393115001053	Ribosomal protein S11; Region: Ribosomal_S11; cl00332
393115001054	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
393115001055	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
393115001056	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115001057	RNA binding surface [nucleotide binding]; other site
393115001058	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
393115001059	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
393115001060	alphaNTD homodimer interface [polypeptide binding]; other site
393115001061	alphaNTD - beta interaction site [polypeptide binding]; other site
393115001062	alphaNTD - beta' interaction site [polypeptide binding]; other site
393115001063	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; cl11613
393115001064	Ribosomal protein L17; Region: Ribosomal_L17; cl00356
393115001065	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001066	Integrase core domain; Region: rve; cl01316
393115001067	ISFtu2, fragment. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa) over 156 aa. Only the carboxy terminal is present and that is disrupted by the insertion of ISFtu1 element resulting in 7 carboxyl aa missing.
393115001068	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
393115001069	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001070	Integrase core domain; Region: rve; cl01316
393115001071	heat shock protein 90; Provisional; Region: PRK05218
393115001072	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115001073	ATP binding site [chemical binding]; other site
393115001074	Mg2+ binding site [ion binding]; other site
393115001075	G-X-G motif; other site
393115001076	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001077	Integrase core domain; Region: rve; cl01316
393115001078	Similar to Q9I5X7 Hypothetical protein PA0559 from Pseudomonas aeruginosa (392 aa). FASTA: opt: 1403 Z-score: 1598.9 E(): 3.3e-81 Smith-Waterman score: 1403; 54.090identity in 379 aa overlap. This CDS contains no start codon due to an insertion of an ISFtu1 element as well as a frameshift and two in-frame stop codons. ORF ftt0358
393115001079	Helix-turn-helix domains; Region: HTH; cl00088
393115001080	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
393115001081	short chain dehydrogenase; Validated; Region: PRK06182
393115001082	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
393115001083	NADP binding site [chemical binding]; other site
393115001084	active site
393115001085	steroid binding site; other site
393115001086	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
393115001087	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001088	Integrase core domain; Region: rve; cl01316
393115001089	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
393115001090	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
393115001091	ferredoxin-NADP reductase; Provisional; Region: PRK10926
393115001092	FAD binding pocket [chemical binding]; other site
393115001093	FAD binding motif [chemical binding]; other site
393115001094	phosphate binding motif [ion binding]; other site
393115001095	beta-alpha-beta structure motif; other site
393115001096	NAD binding pocket [chemical binding]; other site
393115001097	Ribosomal protein L31; Region: Ribosomal_L31; cl00377
393115001098	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl15791
393115001099	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
393115001100	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
393115001101	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
393115001102	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
393115001103	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
393115001104	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl15772
393115001105	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
393115001106	active site
393115001107	multimer interface [polypeptide binding]; other site
393115001108	CTP synthetase; Validated; Region: pyrG; PRK05380
393115001109	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
393115001110	Catalytic site [active]
393115001111	active site
393115001112	UTP binding site [chemical binding]; other site
393115001113	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
393115001114	active site
393115001115	putative oxyanion hole; other site
393115001116	catalytic triad [active]
393115001117	Similar to YFCC_ECOLI (P39263) Hypothetical protein yfcC from E. coli (506 aa). FASTA: opt: 1158 Z-score: 1316.5 E(): 1.8e-65 Smith-Waterman score: 1398; 42.656 identity in 497 aa overlap. Contains an in-frame stop aa after codon 283 and an internal in-frame deletion according to FASTA hits ORF ftt0375
393115001118	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001119	Integrase core domain; Region: rve; cl01316
393115001120	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
393115001121	ISFtu2, fragment. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa) in 157 aa overlap.
393115001122	glutamate dehydrogenase; Provisional; Region: PRK09414
393115001123	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
393115001124	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
393115001125	NAD(P) binding site [chemical binding]; other site
393115001126	Transposase domain (DUF772); Region: DUF772; cl15789
393115001127	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115001128	Transposase domain (DUF772); Region: DUF772; cl15789
393115001129	Phosphatidylserine decarboxylase; Region: PS_Dcarbxylase; cl03656
393115001130	bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; Provisional; Region: PRK05379
393115001131	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional proteins, also containing a Nudix hydrolase domain; Region: NMNAT_Nudix; cd02168
393115001132	active site
393115001133	(T/H)XGH motif; other site
393115001134	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_15; cd04673
393115001135	nudix motif; other site
393115001136	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: glmU; TIGR01173
393115001137	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
393115001138	Substrate binding site; other site
393115001139	Mg++ binding site; other site
393115001140	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
393115001141	active site
393115001142	substrate binding site [chemical binding]; other site
393115001143	CoA binding site [chemical binding]; other site
393115001144	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
393115001145	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
393115001146	glutaminase active site [active]
393115001147	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
393115001148	dimer interface [polypeptide binding]; other site
393115001149	active site
393115001150	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
393115001151	dimer interface [polypeptide binding]; other site
393115001152	active site
393115001153	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
393115001154	Ribosomal protein S21; Region: Ribosomal_S21; cl00529
393115001155	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; Region: CSP_CDS; cd04458
393115001156	DNA-binding site [nucleotide binding]; DNA binding site
393115001157	RNA-binding motif; other site
393115001158	MazG nucleotide pyrophosphohydrolase domain; Region: MazG; cl00345
393115001159	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
393115001160	active site
393115001161	Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif; Region: PLDc_unchar6; cd09176
393115001162	PLD-like domain; Region: PLDc_2; pfam13091
393115001163	putative homodimer interface [polypeptide binding]; other site
393115001164	putative active site [active]
393115001165	catalytic site [active]
393115001166	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
393115001167	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA...; Region: TOP4c; cd00187
393115001168	CAP-like domain; other site
393115001169	active site
393115001170	primary dimer interface [polypeptide binding]; other site
393115001171	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
393115001172	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Provisional; Region: PRK07164
393115001173	BNR repeat-like domain; Region: BNR_2; pfam13088
393115001174	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
393115001175	catalytic site [active]
393115001176	Asp-box motif; other site
393115001177	lytic murein transglycosylase; Provisional; Region: PRK11619
393115001178	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic 'goose-type' lysozymes (GEWL).  LTs catalyze...; Region: LT_GEWL; cd00254
393115001179	N-acetyl-D-glucosamine binding site [chemical binding]; other site
393115001180	catalytic residue [active]
393115001181	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
393115001182	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
393115001183	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
393115001184	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
393115001185	generic binding surface II; other site
393115001186	generic binding surface I; other site
393115001187	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
393115001188	active site
393115001189	catalytic residues [active]
393115001190	metal binding site [ion binding]; metal-binding site
393115001191	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
393115001192	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
393115001193	FtsX-like permease family; Region: FtsX; cl15850
393115001194	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
393115001195	This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE).  They are clustered together...; Region: ABC_MJ0796_Lo1CDE_FtsE; cd03255
393115001196	Walker A/P-loop; other site
393115001197	ATP binding site [chemical binding]; other site
393115001198	Q-loop/lid; other site
393115001199	ABC transporter signature motif; other site
393115001200	Walker B; other site
393115001201	D-loop; other site
393115001202	H-loop/switch region; other site
393115001203	lysine decarboxylase LdcC; Provisional; Region: PRK15399
393115001204	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl09944
393115001205	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
393115001206	homodimer interface [polypeptide binding]; other site
393115001207	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115001208	catalytic residue [active]
393115001209	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
393115001210	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
393115001211	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
393115001212	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
393115001213	lipoyl attachment site [posttranslational modification]; other site
393115001214	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
393115001215	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
393115001216	tetramer interface [polypeptide binding]; other site
393115001217	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115001218	catalytic residue [active]
393115001219	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG1003
393115001220	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
393115001221	tetramer interface [polypeptide binding]; other site
393115001222	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115001223	catalytic residue [active]
393115001224	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
393115001225	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
393115001226	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
393115001227	shikimate binding site; other site
393115001228	NAD(P) binding site [chemical binding]; other site
393115001229	pullulanase, type I; Region: pulA_typeI; TIGR02104
393115001230	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
393115001231	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
393115001232	Ca binding site [ion binding]; other site
393115001233	active site
393115001234	catalytic site [active]
393115001235	glycogen branching enzyme; Provisional; Region: PRK12313
393115001236	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
393115001237	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
393115001238	active site
393115001239	catalytic site [active]
393115001240	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
393115001241	phosphoglucomutase; Region: PLN02307
393115001242	Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction; Region: PGM1; cd03085
393115001243	substrate binding site [chemical binding]; other site
393115001244	dimer interface [polypeptide binding]; other site
393115001245	active site
393115001246	metal binding site [ion binding]; metal-binding site
393115001247	Similar to GLGC_ECOLI (P00584) Glucose-1-phosphate adenylyltransferase from E coli (430 aa). FASTA: opt: 1820 Z-score: 2287.0 E(): 1.7e-119 Smith-Waterman score: 1820; 59.198identity in 424 aa overlap
393115001248	glycogen synthase; Provisional; Region: glgA; PRK00654
393115001249	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
393115001250	ADP-binding pocket [chemical binding]; other site
393115001251	homodimer interface [polypeptide binding]; other site
393115001252	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
393115001253	homodimer interface [polypeptide binding]; other site
393115001254	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
393115001255	active site pocket [active]
393115001256	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
393115001257	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
393115001258	dimer interface [polypeptide binding]; other site
393115001259	motif 1; other site
393115001260	active site
393115001261	motif 2; other site
393115001262	motif 3; other site
393115001263	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
393115001264	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
393115001265	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001266	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115001267	Similar to Q8ZRH1 Putative outer membrane lipoprotein from Salmonella typhimurium (119 aa). FASTA: opt: 327 Z-score: 429.7 bits: 84.9 E(): 4.4e-16 Smith-Waterman score: 327; 43.860 identity in 114 aa overlap ORF ftt0421
393115001268	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
393115001269	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
393115001270	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001271	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
393115001272	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115001273	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; cl15856
393115001274	Similar to Q8A541 Aspartokinase/homoserine dehydrogenase from Bacteriodes thetaiotamicron (811 aa). FASTA: opt: 1065 Z-score: 1231.9 E(): 1e-60 Smith-Waterman score: 1346; 32.025 identity in 815 aa overlap
393115001275	Similar to Q8PLH7 Homoserine kinase from Xanthomonas axonopodis (306 aa). FASTA: opt: 458 Z-score: 540.1 E(): 3.1e-22 Smith-Waterman score: 563; 36.246 identity in 309 aa overlap
393115001276	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
393115001277	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
393115001278	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001279	catalytic residue [active]
393115001280	Similar to Q8FA02 Beta-galactosidase I from Leptospira interrogans (658 aa). FASTA: opt: 260 Z-score: 363.2 E(): 2.4e-12 Smith-Waterman score: 260; 50.000 39dentity in 76 aa overlap
393115001281	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
393115001282	spermidine synthase; Provisional; Region: PRK00811
393115001283	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115001284	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
393115001285	dimer interface [polypeptide binding]; other site
393115001286	active site
393115001287	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115001288	catalytic residues [active]
393115001289	substrate binding site [chemical binding]; other site
393115001290	agmatine deiminase; Region: agmatine_aguA; TIGR03380
393115001291	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; cl01113
393115001292	N-carbamolyputrescine amidase; Region: PLN02747
393115001293	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
393115001294	putative active site; other site
393115001295	catalytic triad [active]
393115001296	putative dimer interface [polypeptide binding]; other site
393115001297	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
393115001298	putative active site [active]
393115001299	putative metal binding site [ion binding]; other site
393115001300	orotate phosphoribosyltransferase; Validated; Region: pyrE; PRK00455
393115001301	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115001302	active site
393115001303	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
393115001304	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
393115001305	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001306	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115001307	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
393115001308	SpoU rRNA Methylase family; Region: SpoU_methylase; cl00362
393115001309	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001310	Integrase core domain; Region: rve; cl01316
393115001311	Similar to Q8M6V4 NADH dehydrogenase subunit 5 (Fragment) from Prioneris autothisbe (291 aa). FASTA: opt: 168 Z-score: 205.5 E(): 0.0013 Smith-Waterman score: 172; 28.241identity in 216 aa overlap. Contains a frameshift after aa 123 and a possible deletion on C-terminal ORF ftt0441c
393115001312	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001313	putative substrate translocation pore; other site
393115001314	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
393115001315	Predicted membrane protein [Function unknown]; Region: COG4129
393115001316	Fusaric acid resistance protein-like; Region: FUSC_2; cl15844
393115001317	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001318	putative substrate translocation pore; other site
393115001319	Similar to Q9HZI7 Probable ATP-binding component of ABC transporter from Pseudomonas aeruginosa (640 aa). FASTA: opt: 1264 Z-score: 1173.6 E(): 1.8e-57 Smith-Waterman score: 1355; 38.629 identity in 642 aa overlap. Contains an in-frame stop codon after aa 389 and a frameshift after aa 584. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115001320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115001321	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
393115001322	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl15769
393115001323	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
393115001324	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115001325	active site
393115001326	HIGH motif; other site
393115001327	nucleotide binding site [chemical binding]; other site
393115001328	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
393115001329	KMSKS motif; other site
393115001330	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
393115001331	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
393115001332	active site
393115001333	metal-binding site [ion binding]
393115001334	nucleotide-binding site [chemical binding]; other site
393115001335	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
393115001336	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
393115001337	Mg++ binding site [ion binding]; other site
393115001338	putative catalytic motif [active]
393115001339	putative substrate binding site [chemical binding]; other site
393115001340	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
393115001341	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001342	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115001343	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
393115001344	YdjC-like protein; Region: YdjC; cl01344
393115001345	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
393115001346	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
393115001347	Ligand binding site; other site
393115001348	Putative Catalytic site; other site
393115001349	DXD motif; other site
393115001350	Endoplasmic reticulum-based factor for assembly of V-ATPase; Region: Vma12; pfam11712
393115001351	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl15769
393115001352	Bacterial Fe(2+) trafficking; Region: Iron_traffic; cl01104
393115001353	DsrC like protein; Region: DsrC; cl01101
393115001354	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115001355	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
393115001356	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
393115001357	dimer interface [polypeptide binding]; other site
393115001358	N-terminal domain interface [polypeptide binding]; other site
393115001359	putative inner membrane peptidase; Provisional; Region: PRK11778
393115001360	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
393115001361	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
393115001362	tandem repeat interface [polypeptide binding]; other site
393115001363	oligomer interface [polypeptide binding]; other site
393115001364	active site residues [active]
393115001365	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
393115001366	DNA polymerase III subunit delta'; Validated; Region: PRK07993
393115001367	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115001368	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663
393115001369	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
393115001370	dimer interface [polypeptide binding]; other site
393115001371	active site
393115001372	Schiff base residues; other site
393115001373	SpoU rRNA Methylase family; Region: SpoU_methylase; cl00362
393115001374	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
393115001375	active site
393115001376	homotetramer interface [polypeptide binding]; other site
393115001377	homodimer interface [polypeptide binding]; other site
393115001378	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
393115001379	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; cl04104
393115001380	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115001381	active site
393115001382	HIGH motif; other site
393115001383	nucleotide binding site [chemical binding]; other site
393115001384	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
393115001385	KMSK motif region; other site
393115001386	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
393115001387	tRNA binding surface [nucleotide binding]; other site
393115001388	anticodon binding site; other site
393115001389	Organic solvent tolerance protein; Region: OstA_C; pfam04453
393115001390	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
393115001391	SurA N-terminal domain; Region: SurA_N_3; cl07813
393115001392	PPIC-type PPIASE domain; Region: Rotamase; cl08278
393115001393	PPIC-type PPIASE domain; Region: Rotamase; cl08278
393115001394	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115001395	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
393115001396	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
393115001397	active site
393115001398	metal binding site [ion binding]; metal-binding site
393115001399	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
393115001400	trimer interface [polypeptide binding]; other site
393115001401	active site
393115001402	dimer interface [polypeptide binding]; other site
393115001403	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
393115001404	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
393115001405	carboxyltransferase (CT) interaction site; other site
393115001406	biotinylation site [posttranslational modification]; other site
393115001407	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
393115001408	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115001409	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115001410	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; cl08365
393115001411	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
393115001412	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
393115001413	Mechanosensitive ion channel; Region: MS_channel; pfam00924
393115001414	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it attaches...; Region: class_II_aaRS-like_core; cl00268
393115001415	EF-P lysine aminoacylase GenX; Region: genX; TIGR00462
393115001416	motif 1; other site
393115001417	dimer interface [polypeptide binding]; other site
393115001418	active site
393115001419	motif 2; other site
393115001420	motif 3; other site
393115001421	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
393115001422	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
393115001423	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
393115001424	DHH family; Region: DHH; pfam01368
393115001425	DHHA1 domain; Region: DHHA1; pfam02272
393115001426	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; cl00465
393115001427	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
393115001428	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
393115001429	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115001430	Protein of unknown function (DUF3281); Region: DUF3281; pfam11685
393115001431	GTPase RsgA; Reviewed; Region: PRK00098
393115001432	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115001433	RNA binding site [nucleotide binding]; other site
393115001434	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
393115001435	GTPase/Zn-binding domain interface [polypeptide binding]; other site
393115001436	GTP/Mg2+ binding site [chemical binding]; other site
393115001437	G4 box; other site
393115001438	G5 box; other site
393115001439	G1 box; other site
393115001440	Switch I region; other site
393115001441	G2 box; other site
393115001442	G3 box; other site
393115001443	Switch II region; other site
393115001444	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; cl01951
393115001445	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; cl01951
393115001446	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
393115001447	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115001448	ATP binding site [chemical binding]; other site
393115001449	Mg2+ binding site [ion binding]; other site
393115001450	G-X-G motif; other site
393115001451	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
393115001452	ATP binding site [chemical binding]; other site
393115001453	MutL C terminal dimerisation domain; Region: MutL_C; cl07336
393115001454	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001455	putative substrate translocation pore; other site
393115001456	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001457	putative substrate translocation pore; other site
393115001458	thioredoxin reductase; Provisional; Region: PRK10262
393115001459	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115001460	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
393115001461	PLD-like domain; Region: PLDc_2; pfam13091
393115001462	putative active site [active]
393115001463	catalytic site [active]
393115001464	Putative catalytic domain, repeat 2, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins; Region: PLDc_vPLD3_4_5_like_2; cd09107
393115001465	PLD-like domain; Region: PLDc_2; pfam13091
393115001466	putative active site [active]
393115001467	putative catalytic site [active]
393115001468	phosphoglycolate phosphatase; Provisional; Region: PRK13222
393115001469	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115001470	motif II; other site
393115001471	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115001472	Helix-turn-helix domains; Region: HTH; cl00088
393115001473	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115001474	putative effector binding pocket; other site
393115001475	dimerization interface [polypeptide binding]; other site
393115001476	Similar to Q8A342 Putative transmembrane efflux protein from Bacteroides thetaiotaomicron (380 aa). FASTA: opt: 990 Z-score: 985.6 E(): 5.3e-47 Smith-Waterman score: 990; 42.487 identity in 386 aa overlap. Contains a frameshift after aa 213 ORF ftt0493
393115001477	CutC family; Region: CutC; cl01218
393115001478	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
393115001479	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
393115001480	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
393115001481	Similar to ASGX_PYRAB (Q9V262) Putative L-asparaginase from Pyrococcus abyssi (305 aa). FASTA: opt: 407 Z-score: 472.8 E(): 1.8e-18 Smith-Waterman score: 431; 34.483 identity in 290 aa overlap. Contains a frameshift after aa 37 ORF ftt0497c
393115001482	Similar to AAO80296 (Q838K6)Di-/tripeptide transporter from Enterococcus faecalis (493 aa). FASTA: opt: 907 Z-score: 1018.4 E(): 7.1e-49 Smith-Waterman score: 907; 34.623 identity in 491 aa overlap. Contains 2 in-frame stop codons after aa 379 and 420 ORF ftt0498c
393115001483	D-alanine-D-alanine ligase and related ATP-grasp enzymes [Cell envelope biogenesis, outer membrane]; Region: DdlA; COG1181
393115001484	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115001485	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
393115001486	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
393115001487	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115001488	CoA-ligase; Region: Ligase_CoA; cl02894
393115001489	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
393115001490	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115001491	CoA-ligase; Region: Ligase_CoA; cl02894
393115001492	Uncharacterized protein conserved in bacteria (DUF2062); Region: DUF2062; cl01261
393115001493	TIGR03545 family protein; Region: TIGR03545
393115001494	TIGR03545 family protein; Region: TIGR03545
393115001495	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115001496	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
393115001497	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
393115001498	FMN binding site [chemical binding]; other site
393115001499	active site
393115001500	catalytic residues [active]
393115001501	substrate binding site [chemical binding]; other site
393115001502	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cl15777
393115001503	putative active site pocket [active]
393115001504	dimerization interface [polypeptide binding]; other site
393115001505	putative catalytic residue [active]
393115001506	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
393115001507	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115001508	Mg2+ binding site [ion binding]; other site
393115001509	G-X-G motif; other site
393115001510	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
393115001511	anchoring element; other site
393115001512	dimer interface [polypeptide binding]; other site
393115001513	ATP binding site [chemical binding]; other site
393115001514	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
393115001515	active site
393115001516	putative metal-binding site [ion binding]; other site
393115001517	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
393115001518	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
393115001519	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
393115001520	active site
393115001521	multimer interface [polypeptide binding]; other site
393115001522	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
393115001523	predicted active site [active]
393115001524	catalytic triad [active]
393115001525	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001526	Integrase core domain; Region: rve; cl01316
393115001527	Similar to Q9KKW6 L-lactate dehydrogenase from Vibrio cholerae (378 aa). FASTA: opt: 927 Z-score: 1134.7 E(): 2.6e-55 Smith-Waterman score: 999; 43.005 identity in 386 aa overlap. Contains a frameshift after aa 179
393115001528	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
393115001529	Similar to Q8D5V2 Fe-S oxidoreductase from Vibrio vulnificus (946 aa). FASTA: opt: 1932 Z-score: 2064.4 E(): 3.9e-107 Smith-Waterman score: 2293; 36.670 identity in 1039 aa overlap. Contains a ~40 aa insertion,a frameshift at a heptanucleotide sequence after aa 307 and so could be part of a programmed translational frameshift, an in-frame stop codon after aa 326 and a 2nd frame shift after aa 600 ORF ftt0516
393115001530	Similar to Q8YNJ9 NADH-dependent butanol dehydrogenase from Anabaena sp. (384 aa). FASTA: opt: 1347 Z-score: 1668.9 E(): 4.6e-85 Smith-Waterman score: 1347; 52.468 identity in 385 aa overlap. contains a frameshift after aa 175. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0517
393115001531	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
393115001532	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115001533	S-adenosylmethionine binding site [chemical binding]; other site
393115001534	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
393115001535	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
393115001536	FMN binding site [chemical binding]; other site
393115001537	active site
393115001538	catalytic residues [active]
393115001539	substrate binding site [chemical binding]; other site
393115001540	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
393115001541	Similar to Q8KDY9 Hypothetical protein CT0905 from (173 aa). opt: 268 Z-score: 346.0 E(): 2e-11 Smith-Waterman score: 268; 54.795 identity in 73 aa overlap. Contains no start codon due to a deletion at N-terminal ORF ftt0521
393115001542	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
393115001543	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
393115001544	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
393115001545	putative active site [active]
393115001546	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
393115001547	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115001548	Walker A/P-loop; other site
393115001549	ATP binding site [chemical binding]; other site
393115001550	ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.  The...; Region: ABC_ATPase; cd00267
393115001551	Walker B; other site
393115001552	D-loop; other site
393115001553	H-loop/switch region; other site
393115001554	Similar to Q87Y22 DNA polymerase IV from pseudomonas syringae (353 aa). FASTA: opt: 1041 Z-score: 1243.0 E(): 2.4e-61 Smith-Waterman score: 1041; 49.153 identity in 354 aa overlap. Contains a frameshift after aa 128
393115001555	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
393115001556	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
393115001557	conserved cys residue [active]
393115001558	Similar to Q8DCS3 ATPase component of ABC transporter with duplicated ATPase domains from Vibrio vulnificus (640 aa). FASTA: opt: 1907 Z-score: 1707.3 E(): 3.3e-87 Smith-Waterman score: 1907; 46.468 identity in 637 aa overlap. Contains a frameshift after aa 65 ORF ftt0531
393115001559	bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta; Provisional; Region: PRK12759
393115001560	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
393115001561	GSH binding site [chemical binding]; other site
393115001562	catalytic residues [active]
393115001563	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
393115001564	dimer interface [polypeptide binding]; other site
393115001565	putative radical transfer pathway; other site
393115001566	diiron center [ion binding]; other site
393115001567	tyrosyl radical; other site
393115001568	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
393115001569	GSH binding site [chemical binding]; other site
393115001570	catalytic residues [active]
393115001571	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
393115001572	Class I ribonucleotide reductase; Region: RNR_I; cd01679
393115001573	active site
393115001574	dimer interface [polypeptide binding]; other site
393115001575	catalytic residues [active]
393115001576	effector binding site; other site
393115001577	R2 peptide binding site; other site
393115001578	malate dehydrogenase; Reviewed; Region: PRK06223
393115001579	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
393115001580	NAD(P) binding site [chemical binding]; other site
393115001581	dimer interface [polypeptide binding]; other site
393115001582	tetramer (dimer of dimers) interface [polypeptide binding]; other site
393115001583	substrate binding site [chemical binding]; other site
393115001584	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
393115001585	diiron binding motif [ion binding]; other site
393115001586	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic 'goose-type' lysozymes (GEWL).  LTs catalyze...; Region: LT_GEWL; cd00254
393115001587	N-acetyl-D-glucosamine binding site [chemical binding]; other site
393115001588	catalytic residue [active]
393115001589	Similar to Q8XPA8 Hypothetical protein CPE0057 from Clostridium perfringens (253 aa). FASTA: opt: 568 Z-score: 689.2 E(): 1.7e-30 Smith-Waterman score: 568; 46.961 identity in 181 aa overlap. Contains an in-frame stop codon after aa 181 ORF ftt0539c
393115001590	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115001591	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
393115001592	Similar to Q88NW9 Antioxidant,AhpC/Tsa family from Pseudomonas putida (200 aa). FASTA: opt: 979 Z-score: 1280.5 E(): 2e-63 Smith-Waterman score: 979; 72.680 identity in 194 aa overlap. Contains a frameshift after aa 108 unknown EC_number 1.6.4.- ORF ftt0542
393115001593	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
393115001594	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
393115001595	PhnA protein; Region: PhnA; pfam03831
393115001596	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
393115001597	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
393115001598	active site
393115001599	substrate binding site [chemical binding]; other site
393115001600	catalytic site [active]
393115001601	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
393115001602	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
393115001603	Similar to Q92LL0 Hypothetical protein R03032 from Rhizobium meliloti (367 aa). FASTA: opt: 921 Z-score: 1129.8 E(): 4.9e-55 Smith-Waterman score: 921; 44.186 identity in 344 aa overlap. Contains a frameshift after aa 102. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift. ORF ftt0551
393115001604	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
393115001605	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
393115001606	tetrameric interface [polypeptide binding]; other site
393115001607	NAD binding site [chemical binding]; other site
393115001608	catalytic residues [active]
393115001609	Domain of unknown function (DUF1338); Region: DUF1338; cl02226
393115001610	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
393115001611	putative homotetramer interface [polypeptide binding]; other site
393115001612	putative homodimer interface [polypeptide binding]; other site
393115001613	putative allosteric switch controlling residues; other site
393115001614	putative metal binding site [ion binding]; other site
393115001615	putative homodimer-homodimer interface [polypeptide binding]; other site
393115001616	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115001617	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
393115001618	Helix-turn-helix domains; Region: HTH; cl00088
393115001619	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
393115001620	dimerization interface [polypeptide binding]; other site
393115001621	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
393115001622	catalytic triad [active]
393115001623	dimer interface [polypeptide binding]; other site
393115001624	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
393115001625	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115001626	NAD(P) binding site [chemical binding]; other site
393115001627	active site
393115001628	cytidylate kinase; Provisional; Region: cmk; PRK00023
393115001629	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
393115001630	CMP-binding site; other site
393115001631	The sites determining sugar specificity; other site
393115001632	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
393115001633	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
393115001634	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001635	catalytic residue [active]
393115001636	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115001637	Integrase core domain; Region: rve; cl01316
393115001638	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
393115001639	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115001640	Walker A/P-loop; other site
393115001641	ATP binding site [chemical binding]; other site
393115001642	Q-loop/lid; other site
393115001643	ABC transporter signature motif; other site
393115001644	Walker B; other site
393115001645	D-loop; other site
393115001646	H-loop/switch region; other site
393115001647	TOBE domain; Region: TOBE_2; cl01440
393115001648	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115001649	dimer interface [polypeptide binding]; other site
393115001650	conserved gate region; other site
393115001651	putative PBP binding loops; other site
393115001652	ABC-ATPase subunit interface; other site
393115001653	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115001654	dimer interface [polypeptide binding]; other site
393115001655	conserved gate region; other site
393115001656	putative PBP binding loops; other site
393115001657	ABC-ATPase subunit interface; other site
393115001658	Transposase domain (DUF772); Region: DUF772; cl15789
393115001659	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115001660	Transposase domain (DUF772); Region: DUF772; cl15789
393115001661	Similar to Q83DZ8 Proton/peptide symporter family protein from Coxiella burnetii (504 aa). FASTA: opt: 434 Z-score: 486.3 E(): 3.4e-19 Smith-Waterman score: 434; 22.400identity in 500 aa overlap. Contains 2 frameshifts after aa 102 and 334 ORF ftt0567c
393115001662	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
393115001663	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115001664	Integral membrane protein TerC family; Region: TerC; cl10468
393115001665	Protein of unknown function (DUF3301); Region: DUF3301; pfam11743
393115001666	GST_N family, Metaxin subfamily, Metaxin-like proteins; a heterogenous group of proteins, predominantly uncharacterized, with similarity to metaxins and GSTs. Metaxin 1 is a component of a preprotein import complex of the mitochondrial outer membrane. It...; Region: GST_N_Metaxin_like; cd03080
393115001667	putative C-terminal domain interface [polypeptide binding]; other site
393115001668	putative GSH binding site [chemical binding]; other site
393115001669	putative dimer interface [polypeptide binding]; other site
393115001670	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
393115001671	dimer interface [polypeptide binding]; other site
393115001672	substrate binding pocket (H-site) [chemical binding]; other site
393115001673	C-terminal, alpha helical domain of Metaxin and related proteins; Region: GST_C_Metaxin; cd03193
393115001674	putative N-terminal domain interface [polypeptide binding]; other site
393115001675	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115001676	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
393115001677	alanine racemase; Reviewed; Region: alr; PRK00053
393115001678	active site
393115001679	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115001680	dimer interface [polypeptide binding]; other site
393115001681	substrate binding site [chemical binding]; other site
393115001682	catalytic residues [active]
393115001683	Similar to Q83AT4 Amino acid permease family protein from Coxiella burnetii (542 aa). FASTA: opt: 1289 Z-score: 1363.6 E(): 4.6e-68 Smith-Waterman score: 1289; 42.534 identity in 442 aa overlap. Contains an in-frame stop codon after aa 284 and a frameshift after aa 445 ORF ftt0574
393115001684	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
393115001685	Prephenate dehydratase; Region: PDT; pfam00800
393115001686	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
393115001687	putative L-Phe binding site [chemical binding]; other site
393115001688	Protein of unknown function DUF45; Region: DUF45; cl00636
393115001689	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
393115001690	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
393115001691	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
393115001692	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
393115001693	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
393115001694	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001695	catalytic residue [active]
393115001696	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
393115001697	Domain of unknown function DUF59; Region: DUF59; cl00941
393115001698	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
393115001699	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
393115001700	active site
393115001701	(T/H)XGH motif; other site
393115001702	ferredoxin; Validated; Region: PRK07118
393115001703	outer membrane protein A; Reviewed; Region: PRK10808
393115001704	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
393115001705	ligand binding site [chemical binding]; other site
393115001706	CRISPR/Cas system-associated protein Cas9; Region: Csx12; cd09704
393115001707	CRISPR-associated protein Cas9/Csx12, subtype II-B/NMENI; Region: cas_csx12; TIGR03031
393115001708	Similar to Q99YS7 Hypothetical protein SPy1562 from Streptococcus pyogenes (341 aa). FASTA: opt: 377 Z-score: 453.0 E(): 2.4e-17 Smith-Waterman score: 377; 28.526 identity in 312 aa overlap. Contains a frameshift after aa 181 ORF ftt0585
393115001709	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
393115001710	Transposase domain (DUF772); Region: DUF772; cl15789
393115001711	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115001712	Transposase domain (DUF772); Region: DUF772; cl15789
393115001713	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
393115001714	hinge; other site
393115001715	3-phosphoshikimate 1-carboxyvinyltransferase; Region: aroA; TIGR01356
393115001716	active site
393115001717	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
393115001718	RNA/DNA hybrid binding site [nucleotide binding]; other site
393115001719	active site
393115001720	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
393115001721	active site
393115001722	homodimer interface [polypeptide binding]; other site
393115001723	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
393115001724	active site clefts [active]
393115001725	zinc binding site [ion binding]; other site
393115001726	dimer interface [polypeptide binding]; other site
393115001727	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
393115001728	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
393115001729	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001730	catalytic residue [active]
393115001731	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
393115001732	Rubredoxin; Region: Rubredoxin; pfam00301
393115001733	iron binding site [ion binding]; other site
393115001734	Uncharacterized conserved protein [Function unknown]; Region: COG0397; cl00428
393115001735	Uncharacterized ACR, YdiU/UPF0061 family; Region: UPF0061; pfam02696
393115001736	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
393115001737	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
393115001738	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
393115001739	dimer interface [polypeptide binding]; other site
393115001740	active site
393115001741	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
393115001742	dimer interface [polypeptide binding]; other site
393115001743	active site
393115001744	Similar to Q8G3X1 D-xylose-proton symporter from Bifodobacterium longum (517 aa). FASTA: opt: 795 Z-score: 849.1 E(): 2.1e-39 Smith-Waterman score: 795; 33.040 identity in 454 aa overlap. Contains a frameshift after aa 401 ORF ftt0600
393115001745	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115001746	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
393115001747	Similar to Q8KTX3 Putative YbgI protein from Vibrio fischeri (251 aa). FASTA: opt: 818 Z-score: 1022.1 E(): 4.9e-49 Smith-Waterman score: 818; 53.112 identity in 241 aa overlap. Contains a frameshift after aa 140 ORF ftt0606c
393115001748	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
393115001749	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
393115001750	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
393115001751	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
393115001752	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
393115001753	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
393115001754	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
393115001755	active site
393115001756	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
393115001757	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
393115001758	active site
393115001759	substrate binding site [chemical binding]; other site
393115001760	Mg2+ binding site [ion binding]; other site
393115001761	beta-lactamase TEM; Provisional; Region: PRK15442
393115001762	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
393115001763	VirK protein; Region: VirK; pfam06903
393115001764	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
393115001765	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
393115001766	putative active site [active]
393115001767	catalytic triad [active]
393115001768	putative dimer interface [polypeptide binding]; other site
393115001769	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
393115001770	Transporter associated domain; Region: CorC_HlyC; cl08393
393115001771	Uncharacterized protein family UPF0054; Region: UPF0054; cl00402
393115001772	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
393115001773	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115001774	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
393115001775	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
393115001776	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115001777	FeS/SAM binding site; other site
393115001778	TRAM domain; Region: TRAM; cl01282
393115001779	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
393115001780	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115001781	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115001782	thymidine kinase; Provisional; Region: PRK04296
393115001783	trigger factor; Provisional; Region: tig; PRK01490
393115001784	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; cl11587
393115001785	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
393115001786	Clp protease; Region: CLP_protease; pfam00574
393115001787	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
393115001788	oligomer interface [polypeptide binding]; other site
393115001789	active site residues [active]
393115001790	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
393115001791	ClpX C4-type zinc finger; Region: zf-C4_ClpX; cl05964
393115001792	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115001793	Walker A motif; other site
393115001794	ATP binding site [chemical binding]; other site
393115001795	Walker B motif; other site
393115001796	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
393115001797	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
393115001798	Found in ATP-dependent protease La (LON); Region: LON; smart00464
393115001799	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115001800	Walker A motif; other site
393115001801	ATP binding site [chemical binding]; other site
393115001802	Walker B motif; other site
393115001803	arginine finger; other site
393115001804	Subunit ChlI of Mg-chelatase; Region: ChlI; cl12214
393115001805	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
393115001806	IHF dimer interface [polypeptide binding]; other site
393115001807	IHF - DNA interface [nucleotide binding]; other site
393115001808	SurA N-terminal domain; Region: SurA_N_3; cl07813
393115001809	periplasmic folding chaperone; Provisional; Region: PRK10788
393115001810	PPIC-type PPIASE domain; Region: Rotamase; cl08278
393115001811	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115001812	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
393115001813	Hfq, an abundant, ubiquitous RNA-binding protein, functions as a pleiotrophic regulator of RNA metabolism in prokaryotes, required for transcription of some transcripts and degradation of others. Hfq binds small RNA molecules called riboregulators that...; Region: Hfq; cd01716
393115001814	Sm1 motif; other site
393115001815	intra - hexamer interaction site; other site
393115001816	inter - hexamer interaction site [polypeptide binding]; other site
393115001817	nucleotide binding pocket [chemical binding]; other site
393115001818	Sm2 motif; other site
393115001819	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
393115001820	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
393115001821	HflX GTPase family; Region: HflX; cd01878
393115001822	G1 box; other site
393115001823	GTP/Mg2+ binding site [chemical binding]; other site
393115001824	Switch I region; other site
393115001825	G2 box; other site
393115001826	G3 box; other site
393115001827	Switch II region; other site
393115001828	G4 box; other site
393115001829	G5 box; other site
393115001830	hypothetical protein; Provisional; Region: PRK07588
393115001831	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115001832	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
393115001833	HflK protein; Region: hflK; TIGR01933
393115001834	FtsH protease regulator HflC; Provisional; Region: PRK11029
393115001835	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
393115001836	Low molecular weight phosphatase family; Region: LMWPc; cd00115
393115001837	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
393115001838	active site
393115001839	Predicted GTPase [General function prediction only]; Region: COG0218
393115001840	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
393115001841	G1 box; other site
393115001842	GTP/Mg2+ binding site [chemical binding]; other site
393115001843	Switch I region; other site
393115001844	G2 box; other site
393115001845	G3 box; other site
393115001846	Switch II region; other site
393115001847	G4 box; other site
393115001848	G5 box; other site
393115001849	Similar to THRC_METJA (Q58860) Probable threonine synthase (405 aa). FASTA: opt: opt: 987 Z-score: 1131.2 E(): 3.7e-55 Smith-Waterman score: 987; 44.875 identity in 361 aa overlap. Contains 2 frameshifts after aa 121 and 247
393115001850	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; cl07212
393115001851	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; cl07212
393115001852	Dehydratase family; Region: ILVD_EDD; cl00340
393115001853	Similar to Q8A609 Acetolactate synthase large subunit from Bacteroides thetaiotaomicron (565 aa). FASTA: opt: 1850 Z-score: 2038.0 E(): 1.1e-105 Smith-Waterman score: 1850; 50.089 identity in 559 aa overlap. Contains a frameshift after aa 427
393115001854	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
393115001855	putative valine binding site [chemical binding]; other site
393115001856	dimer interface [polypeptide binding]; other site
393115001857	Similar to Q847R5 Ketol acid reductoisomerase mitochondrial from Aster yellows phytoplasma (344 aa). FASTA: opt: 1145 Z-score: 1365.8 E(): 3.5e-68 Smith-Waterman score: 1448; 62.391identity in 343 aa overlap. Contains a frameshift after aa 37 and an in-frame stop codon after aa 74
393115001858	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
393115001859	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
393115001860	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115001861	ATP binding site [chemical binding]; other site
393115001862	putative Mg++ binding site [ion binding]; other site
393115001863	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115001864	nucleotide binding region [chemical binding]; other site
393115001865	ATP-binding site [chemical binding]; other site
393115001866	TRCF domain; Region: TRCF; cl04088
393115001867	YccA-like proteins; Region: YccA_like; cd10433
393115001868	Domain of unknown function (DUF1841); Region: DUF1841; pfam08897
393115001869	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
393115001870	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
393115001871	minor groove reading motif; other site
393115001872	helix-hairpin-helix signature motif; other site
393115001873	substrate binding pocket [chemical binding]; other site
393115001874	active site
393115001875	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
393115001876	electron transport complex protein RnfB; Provisional; Region: PRK05113
393115001877	Putative Fe-S cluster; Region: FeS; pfam04060
393115001878	4Fe-4S binding domain; Region: Fer4; cl02805
393115001879	glutaredoxin 2; Provisional; Region: PRK10387
393115001880	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
393115001881	C-terminal domain interface [polypeptide binding]; other site
393115001882	GSH binding site (G-site) [chemical binding]; other site
393115001883	catalytic residues [active]
393115001884	putative dimer interface [polypeptide binding]; other site
393115001885	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
393115001886	N-terminal domain interface [polypeptide binding]; other site
393115001887	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115001888	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
393115001889	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
393115001890	Ferritin-like domain; Region: Ferritin; pfam00210
393115001891	ferroxidase diiron center [ion binding]; other site
393115001892	lipoyl synthase; Provisional; Region: PRK05481
393115001893	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115001894	FeS/SAM binding site; other site
393115001895	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
393115001896	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
393115001897	conserved cys residue [active]
393115001898	Transcriptional regulator; Region: Transcrip_reg; cl00361
393115001899	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination.  HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD includes...; Region: RuvC_resolvase; cd00529
393115001900	active site
393115001901	putative DNA-binding cleft [nucleotide binding]; other site
393115001902	dimer interface [polypeptide binding]; other site
393115001903	Similar to AAO90981 (Q83BM0) Major facilitator family transporter from coxiella burnetti (428 aa). FASTA: opt: 586 Z-score: 650.3 E(): 2.3e-28 Smith-Waterman score: 600; 27.638 identity in 398 aa overlap. Contains 2 in-frame stop codons after aa 65 and 190 ORF ftt0657
393115001904	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
393115001905	RuvA N terminal domain; Region: RuvA_N; pfam01330
393115001906	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
393115001907	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
393115001908	RmuC family; Region: RmuC; pfam02646
393115001909	Helix-turn-helix domains; Region: HTH; cl00088
393115001910	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4337
393115001911	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
393115001912	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
393115001913	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
393115001914	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001915	catalytic residue [active]
393115001916	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
393115001917	intersubunit interface [polypeptide binding]; other site
393115001918	active site
393115001919	Zn2+ binding site [ion binding]; other site
393115001920	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
393115001921	active site
393115001922	DNA binding site [nucleotide binding]
393115001923	Isochorismatase family; Region: Isochorismatase; pfam00857
393115001924	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
393115001925	catalytic triad [active]
393115001926	conserved cis-peptide bond; other site
393115001927	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
393115001928	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
393115001929	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
393115001930	Mechanosensitive ion channel; Region: MS_channel; pfam00924
393115001931	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001932	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115001933	putative substrate translocation pore; other site
393115001934	Similar to Q83BM0 Major facilitator family transporter from Coxiella burnetii (428 aa). FASTA: opt: 549 Z-score: 638.7 E(): 1.1e-27 Smith-Waterman score: 549; 26.353 identity in 425 aa overlap. Contains a frameshift after aa 109 ORF ftt0672c
393115001935	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_1; cd06251
393115001936	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
393115001937	putative active site [active]
393115001938	Zn binding site [ion binding]; other site
393115001939	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
393115001940	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
393115001941	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115001942	active site
393115001943	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
393115001944	5S rRNA interface [nucleotide binding]; other site
393115001945	CTC domain interface [polypeptide binding]; other site
393115001946	L16 interface [polypeptide binding]; other site
393115001947	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
393115001948	Domain of unknown function DUF21; Region: DUF21; pfam01595
393115001949	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
393115001950	Transporter associated domain; Region: CorC_HlyC; cl08393
393115001951	Methyltransferase domain; Region: Methyltransf_31; pfam13847
393115001952	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115001953	S-adenosylmethionine binding site [chemical binding]; other site
393115001954	GTP-binding protein YchF; Reviewed; Region: PRK09601
393115001955	YchF GTPase; Region: YchF; cd01900
393115001956	G1 box; other site
393115001957	GTP/Mg2+ binding site [chemical binding]; other site
393115001958	Switch I region; other site
393115001959	G2 box; other site
393115001960	Switch II region; other site
393115001961	G3 box; other site
393115001962	G4 box; other site
393115001963	G5 box; other site
393115001964	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
393115001965	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
393115001966	putative active site [active]
393115001967	catalytic residue [active]
393115001968	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
393115001969	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
393115001970	dimerization domain [polypeptide binding]; other site
393115001971	dimer interface [polypeptide binding]; other site
393115001972	catalytic residues [active]
393115001973	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
393115001974	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
393115001975	Type IV leader peptidase family; Region: Peptidase_A24; cl02077
393115001976	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
393115001977	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115001978	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115001979	voltage-gated potassium channel; Provisional; Region: PRK10537
393115001980	Ion channel; Region: Ion_trans_2; cl11596
393115001981	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115001982	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
393115001983	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115001984	Walker A motif; other site
393115001985	ATP binding site [chemical binding]; other site
393115001986	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115001987	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
393115001988	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
393115001989	active site
393115001990	HslU subunit interaction site [polypeptide binding]; other site
393115001991	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
393115001992	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
393115001993	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
393115001994	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
393115001995	active site
393115001996	HIGH motif; other site
393115001997	dimer interface [polypeptide binding]; other site
393115001998	KMSKS motif; other site
393115001999	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
393115002000	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002001	Integrase core domain; Region: rve; cl01316
393115002002	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
393115002003	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
393115002004	DNA binding site [nucleotide binding]
393115002005	catalytic residue [active]
393115002006	H2TH interface [polypeptide binding]; other site
393115002007	putative catalytic residues [active]
393115002008	turnover-facilitating residue; other site
393115002009	intercalation triad [nucleotide binding]; other site
393115002010	8OG recognition residue [nucleotide binding]; other site
393115002011	putative reading head residues; other site
393115002012	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
393115002013	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
393115002014	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
393115002015	AMP-binding enzyme; Region: AMP-binding; cl15778
393115002016	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
393115002017	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002018	Septum formation initiator; Region: DivIC; cl11433
393115002019	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
393115002020	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
393115002021	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
393115002022	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
393115002023	16S/18S rRNA binding site [nucleotide binding]; other site
393115002024	S13e-L30e interaction site [polypeptide binding]; other site
393115002025	25S rRNA binding site [nucleotide binding]; other site
393115002026	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
393115002027	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
393115002028	oligomer interface [polypeptide binding]; other site
393115002029	RNA binding site [nucleotide binding]; other site
393115002030	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
393115002031	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
393115002032	RNase E interface [polypeptide binding]; other site
393115002033	trimer interface [polypeptide binding]; other site
393115002034	active site
393115002035	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
393115002036	putative nucleic acid binding region [nucleotide binding]; other site
393115002037	G-X-X-G motif; other site
393115002038	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115002039	RNA binding site [nucleotide binding]; other site
393115002040	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
393115002041	NeuB family; Region: NeuB; cl00496
393115002042	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
393115002043	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
393115002044	ATP-binding site [chemical binding]; other site
393115002045	Sugar specificity; other site
393115002046	Pyrimidine base specificity; other site
393115002047	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
393115002048	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
393115002049	TRAM domain; Region: TRAM; cl01282
393115002050	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115002051	S-adenosylmethionine binding site [chemical binding]; other site
393115002052	Similar to Q8EQ10 Glucose kinase (EC 2.7.1.2) from Oceanobacillus iheyensis (325 aa). FASTA: opt: 569 Z-score: 642.8 E(): 6.5e-28 Smith-Waterman score: 569; 31.111 identity in 315 aa overlap. Contains a frameshift after aa 254
393115002053	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
393115002054	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115002055	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002056	putative substrate translocation pore; other site
393115002057	enolase; Provisional; Region: eno; PRK00077
393115002058	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
393115002059	dimer interface [polypeptide binding]; other site
393115002060	metal binding site [ion binding]; metal-binding site
393115002061	substrate binding pocket [chemical binding]; other site
393115002062	Septum formation initiator; Region: DivIC; cl11433
393115002063	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
393115002064	substrate binding site; other site
393115002065	dimer interface; other site
393115002066	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
393115002067	Transmembrane amino acid transporter protein; Region: Aa_trans; cl15776
393115002068	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
393115002069	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002070	NAD(P) binding site [chemical binding]; other site
393115002071	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
393115002072	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
393115002073	substrate-cofactor binding pocket; other site
393115002074	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002075	catalytic residue [active]
393115002076	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
393115002077	Glyco_18 domain; Region: Glyco_18; smart00636
393115002078	active site
393115002079	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
393115002080	Chitin/cellulose binding domain. Putative carbohydrate binding domain found in many different glycosyl hydrolase enzymes. May occur in tandem arrangements; Region: ChtBD3; cd00036
393115002081	chitin/cellulose binding site [chemical binding]; other site
393115002082	Chitin/cellulose binding domain. Putative carbohydrate binding domain found in many different glycosyl hydrolase enzymes. May occur in tandem arrangements; Region: ChtBD3; cd00036
393115002083	chitin/cellulose binding site [chemical binding]; other site
393115002084	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115002085	active site
393115002086	Similar to Q9KQK6 Formyltetrahydrofolate deformylase (277 aa). FASTA: opt: 1088 Z-score: 1353.6 E(): 1.7e-67 Smith-Waterman score: 1088; 59.206 identity in 277 aa overlap. Contains a frameshift after aa 81. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115002087	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
393115002088	putative substrate binding pocket [chemical binding]; other site
393115002089	trimer interface [polypeptide binding]; other site
393115002090	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002091	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115002092	putative substrate translocation pore; other site
393115002093	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK05318
393115002094	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
393115002095	Zn2+ binding site [ion binding]; other site
393115002096	Mg2+ binding site [ion binding]; other site
393115002097	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
393115002098	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
393115002099	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
393115002100	heme binding site [chemical binding]; other site
393115002101	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
393115002102	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002103	Integrase core domain; Region: rve; cl01316
393115002104	classical (c) SDRs; Region: SDR_c; cd05233
393115002105	NAD(P) binding site [chemical binding]; other site
393115002106	active site
393115002107	Similar to Q8EEI8 Penicillin-binding protein 4 from Shewanella oneidensis (507 aa) aa). FASTA: opt: 645 Z-score: 721.3 E(): 2.5e-32 Smith-Waterman score: 645; 31.478identity in 467 aa overlap. Contains a frameshift after aa 136. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115002108	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
393115002109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002110	putative substrate translocation pore; other site
393115002111	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
393115002112	Glycerophosphodiester phosphodiesterase domain of putative Silicibacter pomeroyi glycerophosphodiester phosphodiesterase and similar proteins; Region: GDPD_SpGDE_like; cd08567
393115002113	active site
393115002114	catalytic site [active]
393115002115	metal binding site [ion binding]; metal-binding site
393115002116	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
393115002117	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115002118	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
393115002119	This family of ATP-binding proteins belongs to a multisubunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity.  In bacteria and archaea, these transporters usually include an ATP-binding...; Region: ABC_DR_subfamily_A; cd03230
393115002120	Walker A/P-loop; other site
393115002121	ATP binding site [chemical binding]; other site
393115002122	Q-loop/lid; other site
393115002123	ABC transporter signature motif; other site
393115002124	Walker B; other site
393115002125	D-loop; other site
393115002126	H-loop/switch region; other site
393115002127	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
393115002128	ABC-2 type transporter; Region: ABC2_membrane; cl11417
393115002129	Transposase domain (DUF772); Region: DUF772; cl15789
393115002130	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115002131	Transposase domain (DUF772); Region: DUF772; cl15789
393115002132	Chorismate mutase type II; Region: CM_2; cl00693
393115002133	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
393115002134	catalytic residues [active]
393115002135	dimer interface [polypeptide binding]; other site
393115002136	Similar to Q9K8K1 Hypothetical protein BH3005 from Bacillus halodurans (388 aa). FASTA: opt: 934 Z-score: 1058.9 E(): 4.3e-51 Smith-Waterman score: 934; 38.144 identity in 388 aa overlap. Contains an in-frame stop codon after aa 187 ORF ftt0734
393115002137	Similar to Q81CC3 Mandelate racemase/muconate lactonizing enzyme family protein Bacillus cereus (strain ATCC 14579 / DSM 31) (350 aa). FASTA: opt: 653 Z-score: 766.5 E(): 8.4e-35 Smith-Waterman score: 653; 34.877identity in 324 aa overlap. Contains 2 in-frame stop codons after aa 84 and 199 ORF ftt0735
393115002138	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
393115002139	YjeF-related protein N-terminus; Region: YjeF_N; cl00318
393115002140	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
393115002141	putative substrate binding site [chemical binding]; other site
393115002142	putative ATP binding site [chemical binding]; other site
393115002143	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115002144	RNA binding surface [nucleotide binding]; other site
393115002145	OstA-like protein; Region: OstA; cl00844
393115002146	Organic solvent tolerance protein; Region: OstA_C; pfam04453
393115002147	Protein of unknown function (DUF2797); Region: DUF2797; pfam10977
393115002148	Fusaric acid resistance protein family; Region: FUSC; pfam04632
393115002149	Fusaric acid resistance protein family; Region: FUSC; pfam04632
393115002150	Fusaric acid resistance protein-like; Region: FUSC_2; cl15844
393115002151	multidrug resistance protein MdtN; Provisional; Region: PRK10476
393115002152	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115002153	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
393115002154	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115002155	Transcriptional regulator [Transcription]; Region: IclR; COG1414
393115002156	Helix-turn-helix domains; Region: HTH; cl00088
393115002157	Bacterial transcriptional regulator; Region: IclR; pfam01614
393115002158	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
393115002159	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
393115002160	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
393115002161	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115002162	FeS/SAM binding site; other site
393115002163	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; Region: CSP_CDS; cd04458
393115002164	DNA-binding site [nucleotide binding]; DNA binding site
393115002165	RNA-binding motif; other site
393115002166	Ribosomal protein S21; Region: Ribosomal_S21; cl00529
393115002167	Protein of unknown function with HXXEE motif; Region: HXXEE; pfam13787
393115002168	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
393115002169	Cation efflux family; Region: Cation_efflux; cl00316
393115002170	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
393115002171	active site
393115002172	tetramer interface; other site
393115002173	Similar to Q92KX2 Probable acetyl-coenzyme A synthetase 2 from Rhizobium meliloti (Sinorhizobium meliloti) (649 aa). FASTA: opt: 1346 Z-score: 1602.8 E(): 2.2e-81 Smith-Waterman score: 1424; 39.908 identity in 649 aa overlap. Contains an internal deletion after aa 134 that causes a corresponding frameshift
393115002174	EamA-like transporter family; Region: EamA; cl01037
393115002175	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
393115002176	EamA-like transporter family; Region: EamA; cl01037
393115002177	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
393115002178	recombination protein F; Reviewed; Region: recF; PRK00064
393115002179	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002180	Walker A/P-loop; other site
393115002181	ATP binding site [chemical binding]; other site
393115002182	Q-loop/lid; other site
393115002183	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002184	ABC transporter signature motif; other site
393115002185	Walker B; other site
393115002186	D-loop; other site
393115002187	H-loop/switch region; other site
393115002188	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
393115002189	active site
393115002190	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
393115002191	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
393115002192	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002193	Integrase core domain; Region: rve; cl01316
393115002194	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
393115002195	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
393115002196	LPP20 lipoprotein; Region: LPP20; cl15824
393115002197	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
393115002198	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002199	SecA preprotein cross-linking domain; Region: SecA_PP_bind; cl03078
393115002200	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115002201	nucleotide binding region [chemical binding]; other site
393115002202	ATP-binding site [chemical binding]; other site
393115002203	hypothetical protein; Provisional; Region: PRK05590
393115002204	SEC-C motif; Region: SEC-C; pfam02810
393115002205	Similar to Q83EE1 DNA-3-methyladenine glycosidase I from Coxiella burnetii (204 aa). FASTA: opt: 668 Z-score: 863.4 E(): 3.4e-40 Smith-Waterman score: 668; 52.459 identity in 183 aa overlap. Contains an in-frame stop codon after aa 66
393115002206	Similar to GRK_BACHD (Q9Z9P2) Glycerate kinase from Bacillus halodurans (380 aa). FASTA: opt: 992 Z-score: 1181.8 E(): 6.2e-58 Smith-Waterman score: 992; 41.600 identity in 375 aa overlap. Contains 2 frameshifts after aa 136 and 332
393115002207	Ribosomal prokaryotic L21 protein; Region: Ribosomal_L21p; cl00382
393115002208	Ribosomal L27 protein; Region: Ribosomal_L27; cl00359
393115002209	Uncharacterized protein conserved in bacteria (DUF2237); Region: DUF2237; cl01467
393115002210	Similar to Q81IY9 Bicyclomycin resistance protein from Bacillus cereus (strain ATCC 14579 / DSM 31) (416 aa). FASTA: opt: 598 Z-score: 663.2 E(): 4.7e-29 Smith-Waterman score: 598; 28.960 identity in 404 aa overlap. Contains a frameshift after aa 103 Putative drug transport protein.
393115002211	ribonuclease D; Region: rnd; TIGR01388
393115002212	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
393115002213	putative active site [active]
393115002214	catalytic site [active]
393115002215	putative substrate binding site [chemical binding]; other site
393115002216	HRDC domain; Region: HRDC; cl02578
393115002217	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
393115002218	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
393115002219	GIY-YIG motif/motif A; other site
393115002220	active site
393115002221	catalytic site [active]
393115002222	putative DNA binding site [nucleotide binding]; other site
393115002223	metal binding site [ion binding]; metal-binding site
393115002224	UvrB/uvrC motif; Region: UVR; pfam02151
393115002225	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
393115002226	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002227	Integrase core domain; Region: rve; cl01316
393115002228	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
393115002229	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06997
393115002230	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
393115002231	NAD binding site [chemical binding]; other site
393115002232	homotetramer interface [polypeptide binding]; other site
393115002233	homodimer interface [polypeptide binding]; other site
393115002234	substrate binding site [chemical binding]; other site
393115002235	active site
393115002236	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
393115002237	Protein of unknown function (DUF692); Region: DUF692; cl01263
393115002238	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; cl01262
393115002239	DoxX; Region: DoxX; cl00976
393115002240	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
393115002241	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
393115002242	putative active site [active]
393115002243	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
393115002244	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
393115002245	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
393115002246	substrate binding site [chemical binding]; other site
393115002247	hexamer interface [polypeptide binding]; other site
393115002248	metal binding site [ion binding]; metal-binding site
393115002249	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
393115002250	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002251	Bacterial sugar transferase; Region: Bac_transf; cl00939
393115002252	UDP-glucose 4-epimerase; Region: PLN02240
393115002253	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
393115002254	NAD binding site [chemical binding]; other site
393115002255	homodimer interface [polypeptide binding]; other site
393115002256	active site
393115002257	substrate binding site [chemical binding]; other site
393115002258	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115002259	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_4; cd03795
393115002260	putative ADP-binding pocket [chemical binding]; other site
393115002261	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
393115002262	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
393115002263	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002264	Walker A/P-loop; other site
393115002265	ATP binding site [chemical binding]; other site
393115002266	Q-loop/lid; other site
393115002267	ABC transporter signature motif; other site
393115002268	Walker B; other site
393115002269	D-loop; other site
393115002270	H-loop/switch region; other site
393115002271	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
393115002272	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115002273	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
393115002274	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
393115002275	active site
393115002276	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002277	LicD family; Region: LicD; cl01378
393115002278	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
393115002279	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
393115002280	active site
393115002281	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
393115002282	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
393115002283	active site
393115002284	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
393115002285	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
393115002286	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115002287	motif II; other site
393115002288	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
393115002289	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
393115002290	substrate binding site [chemical binding]; other site
393115002291	ATP binding site [chemical binding]; other site
393115002292	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
393115002293	proposed catalytic triad [active]
393115002294	active site nucleophile [active]
393115002295	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
393115002296	catalytic nucleophile [active]
393115002297	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002298	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115002299	putative substrate translocation pore; other site
393115002300	poly-gamma-glutamate synthase PgsB/CapB; Region: poly_gGlu_PgsB; TIGR04012
393115002301	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115002302	Capsule biosynthesis CapC; Region: Caps_synth_CapC; cl14855
393115002303	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
393115002304	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
393115002305	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
393115002306	synthetase active site [active]
393115002307	NTP binding site [chemical binding]; other site
393115002308	metal binding site [ion binding]; metal-binding site
393115002309	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
393115002310	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
393115002311	recombination protein RecR; Provisional; Region: PRK13844
393115002312	RecR protein; Region: RecR; pfam02132
393115002313	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
393115002314	putative active site [active]
393115002315	putative metal-binding site [ion binding]; other site
393115002316	tetramer interface [polypeptide binding]; other site
393115002317	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
393115002318	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
393115002319	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
393115002320	homodimer interface [polypeptide binding]; other site
393115002321	active site
393115002322	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
393115002323	lipoyl attachment site [posttranslational modification]; other site
393115002324	Chitin binding domain; Region: Chitin_bind_3; cl03871
393115002325	Chitin/cellulose binding domain. Putative carbohydrate binding domain found in many different glycosyl hydrolase enzymes. May occur in tandem arrangements; Region: ChtBD3; cl00046
393115002326	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
393115002327	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
393115002328	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469
393115002329	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
393115002330	active site
393115002331	dimer interface [polypeptide binding]; other site
393115002332	motif 1; other site
393115002333	motif 2; other site
393115002334	motif 3; other site
393115002335	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
393115002336	anticodon binding site; other site
393115002337	translation initiation factor IF-3; Region: infC; TIGR00168
393115002338	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
393115002339	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
393115002340	Ribosomal protein L35; Region: Ribosomal_L35p; cl00392
393115002341	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
393115002342	23S rRNA binding site [nucleotide binding]; other site
393115002343	L21 binding site [polypeptide binding]; other site
393115002344	L13 binding site [polypeptide binding]; other site
393115002345	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115002346	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002347	Integrase core domain; Region: rve; cl01316
393115002348	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
393115002349	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
393115002350	nudix motif; other site
393115002351	Arsenate Reductase (ArsC) family; composed of TRX-fold arsenic reductases and similar proteins including the transcriptional regulator, Spx. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from...; Region: ArsC_family; cd02977
393115002352	ArsC family; Region: ArsC; pfam03960
393115002353	catalytic residue [active]
393115002354	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
393115002355	Similar to Q845W8 L-aspartate-beta-decarboxylase from Pseudomonas dacunhae (533 aa). FASTA: opt: 1854 Z-score: 2243.7 E(): 4.4e-117 Smith-Waterman score: 1854; 54.476 identity in 525 aa overlap. Contains a frameshift after aa 198 ORF ftt0828c
393115002356	aspartate-alanine antiporter; Region: Asp_Ala_antiprt; TIGR03802
393115002357	Predicted Permease Membrane Region; Region: Asp-Al_Ex; cl06061
393115002358	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl15357
393115002359	Predicted Permease Membrane Region; Region: Asp-Al_Ex; cl06061
393115002360	Similar to Q8XJQ3 Smf protein DNA processing chain A from Clostridium perfringens (360 aa). FASTA: 754 Z-score: 848.5 E(): 2.1e-39 Smith-Waterman score: 754; 37.151identity in 358 aa overlap. Contains a frameshift after aa 153. ORF ftt0830c
393115002361	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
393115002362	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
393115002363	ligand binding site [chemical binding]; other site
393115002364	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; cl11587
393115002365	LytB protein; Region: LYTB; cl00507
393115002366	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Region: ispH_lytB; TIGR00216
393115002367	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
393115002368	homotrimer interaction site [polypeptide binding]; other site
393115002369	active site
393115002370	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
393115002371	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
393115002372	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
393115002373	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
393115002374	TolB amino-terminal domain; Region: TolB_N; cl00639
393115002375	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
393115002376	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
393115002377	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
393115002378	ligand binding site [chemical binding]; other site
393115002379	Similar to YLIG_ECOLI Hypothetical protein yliG from Eschericia coli (441 aa). FASTA: opt: 1850 Z-score: 2204.1 E(): 7.1e-115 Smith-Waterman score: 1850; 61.136 identity in 440 aa overlap. Contains a frameshift after aa 185 ORF ftt0843
393115002380	Similar to Q9F7P6 Predicted CsgA,Rossman fold oxidoreductase from Gamma-proteobacterium EBAC31A08 (262 aa). FASTA: opt: 764 Z-score: 936.3 E(): 2.9e-44 Smith-Waterman score: 764; 53.390identity in 236 aa overlap. Contains an in-frame stop codon after aa 59 ORF ftt0844
393115002381	Protein of unknown function (DUF2805); Region: DUF2805; cl11923
393115002382	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
393115002383	DNA photolyase; Region: DNA_photolyase; pfam00875
393115002384	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
393115002385	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
393115002386	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
393115002387	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
393115002388	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; cl01792
393115002389	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
393115002390	Membrane transport protein; Region: Mem_trans; cl09117
393115002391	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
393115002392	YheO-like PAS domain; Region: PAS_6; pfam08348
393115002393	Helix-turn-helix domains; Region: HTH; cl00088
393115002394	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115002395	Predicted permeases [General function prediction only]; Region: COG0730; cl00498
393115002396	Weakly similar to Q8D5E8 Transglutaminase-like enzyme from Vibrio vulnificus (300 aa). FASTA: opt: 336 Z-score: 432.9 E(): 3.2e-16 Smith-Waterman score: 401; 29.779 identity in 272 aa overlap. Contains a frameshift after codon 183 ORF ftt0852
393115002397	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
393115002398	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
393115002399	transmembrane helices; other site
393115002400	Protein of unknown function (DUF423); Region: DUF423; cl01008
393115002401	Protein of unknown function, DUF393; Region: DUF393; cl01136
393115002402	UbiA prenyltransferase family; Region: UbiA; cl00337
393115002403	UTRA domain; Region: UTRA; cl01230
393115002404	ribonuclease PH; Reviewed; Region: rph; PRK00173
393115002405	Ribonuclease PH; Region: RNase_PH_bact; cd11362
393115002406	hexamer interface [polypeptide binding]; other site
393115002407	active site
393115002408	Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968
393115002409	Peptidase family M48; Region: Peptidase_M48; cl12018
393115002410	LemA family; Region: LemA; cl00742
393115002411	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
393115002412	Helix-turn-helix domains; Region: HTH; cl00088
393115002413	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
393115002414	putative dimerization interface [polypeptide binding]; other site
393115002415	Similar to Q83C61 Hypothetical protein from Coxiella burnetii (353 aa). FASTA: opt: 1159 Z-score: 1425.3 E(): 1.7e-71 Smith-Waterman score: 1159; 51.289 identity in 349 aa overlap. Contains a frameshift after aa 61 ORF ftt0865
393115002416	Similar to P58414 Probable cadmium-transporting ATPase from Listeria monocytogenes (707 aa). FASTA: opt: 1598 Z-score: 1734.8 E(): 8.9e-89 Smith-Waterman score: 1632; 38.324 identity in 728 aa overlap. Contains a frameshift after aa 391 and an interruption due to an IS element ORF ftt0866c
393115002417	Transposase domain (DUF772); Region: DUF772; cl15789
393115002418	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115002419	Transposase domain (DUF772); Region: DUF772; cl15789
393115002420	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
393115002421	dimerization interface [polypeptide binding]; other site
393115002422	putative DNA binding site [nucleotide binding]; other site
393115002423	putative Zn2+ binding site [ion binding]; other site
393115002424	Peptidase_C39 like family; Region: Peptidase_C39_2; pfam13529
393115002425	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the 'double-glycine' leader peptides from the precursors of various bacteriocins; Region: Peptidase_C39A; cd02549
393115002426	putative active site [active]
393115002427	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
393115002428	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002429	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
393115002430	Colicin V production protein; Region: Colicin_V; cl00567
393115002431	DNA repair protein RadA; Provisional; Region: PRK11823
393115002432	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
393115002433	Walker A motif/ATP binding site; other site
393115002434	ATP binding site [chemical binding]; other site
393115002435	Walker B motif; other site
393115002436	Subunit ChlI of Mg-chelatase; Region: ChlI; cl12214
393115002437	PilZ domain; Region: PilZ; cl01260
393115002438	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115002439	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
393115002440	Tetramer interface [polypeptide binding]; other site
393115002441	active site
393115002442	FMN-binding site [chemical binding]; other site
393115002443	PQ loop repeat; Region: PQ-loop; cl12056
393115002444	methionine sulfoxide reductase B; Provisional; Region: PRK00222; cl15841
393115002445	SelR domain; Region: SelR; pfam01641
393115002446	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
393115002447	E-class dimer interface [polypeptide binding]; other site
393115002448	P-class dimer interface [polypeptide binding]; other site
393115002449	active site
393115002450	Cu2+ binding site [ion binding]; other site
393115002451	Zn2+ binding site [ion binding]; other site
393115002452	Similar to Q87PL0 Conserved hypothetical protein from Vibrio parahaemolyticus (275 aa). FASTA: opt: 818 Z-score: 1003.8 E(): 4.6e-48 Smith-Waterman score: 818; 46.457 identity in 254 aa overlap. Contains a frameshift after 21 aa ORF ftt0880
393115002453	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
393115002454	Similar to last 120 amino acids of O30800 Pmi-like gene product from Methylobacterium extorquens (469 aa). FASTA: opt: 448 Z-score: 572.4 E(): 4.9e-24 Smith-Waterman score: 448; 61.111 identity in 108 aa overlap. CDS contains no start codon due to deletion at N-terminal ORF ftt0882
393115002455	deleted EC_number 1.2.1.1; Similar to CAD84818 Alcohol dehydrogenase class III from Ralstonia solanacearum (368 aa). FASTA: opt: 1760 Z-score: 1914.4 E(): 8.8e-99 Smith-Waterman score: 1760; 69.189identity in 370 aa overlap. Contains frameshifts after aa 86 and 105 ORF ftt0883
393115002456	aspartate aminotransferase; Provisional; Region: PRK07568
393115002457	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
393115002458	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002459	homodimer interface [polypeptide binding]; other site
393115002460	catalytic residue [active]
393115002461	Cation efflux family; Region: Cation_efflux; cl00316
393115002462	recombination and repair protein; Provisional; Region: PRK10869
393115002463	RecN ATPase involved in DNA repair; ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and...; Region: ABC_RecN; cd03241
393115002464	Walker A/P-loop; other site
393115002465	ATP binding site [chemical binding]; other site
393115002466	Q-loop/lid; other site
393115002467	RecN ATPase involved in DNA repair; ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and...; Region: ABC_RecN; cd03241
393115002468	ABC transporter signature motif; other site
393115002469	Walker B; other site
393115002470	D-loop; other site
393115002471	H-loop/switch region; other site
393115002472	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
393115002473	Pilin (bacterial filament); Region: Pilin; pfam00114
393115002474	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
393115002475	Pilin (bacterial filament); Region: Pilin; pfam00114
393115002476	PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major...; Region: PAP2_lipid_A_1_phosphatase; cd03389
393115002477	active site
393115002478	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14180
393115002479	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
393115002480	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
393115002481	homodimer interface [polypeptide binding]; other site
393115002482	NADP binding site [chemical binding]; other site
393115002483	substrate binding site [chemical binding]; other site
393115002484	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
393115002485	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
393115002486	dimerization interface [polypeptide binding]; other site
393115002487	putative ATP binding site [chemical binding]; other site
393115002488	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
393115002489	active site
393115002490	ATP binding site [chemical binding]; other site
393115002491	substrate binding site [chemical binding]; other site
393115002492	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
393115002493	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
393115002494	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115002495	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
393115002496	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
393115002497	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
393115002498	active site
393115002499	substrate binding site [chemical binding]; other site
393115002500	cosubstrate binding site; other site
393115002501	catalytic site [active]
393115002502	AIR carboxylase; Region: AIRC; cl00310
393115002503	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
393115002504	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115002505	Restriction endonuclease; Region: Mrr_cat; cl00516
393115002506	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
393115002507	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
393115002508	active site
393115002509	Zn binding site [ion binding]; other site
393115002510	Mth938-like domain. The members of this family include: Mth938, 2P1, Xcr35, Rpa2829, and several uncharacterized sequences. Mth938 is a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome. This protein crystallizes as a...; Region: Mth938-like; cd00248
393115002511	O-Antigen Polymerase; Region: Wzy_C; cl04850
393115002512	DNA topoisomerase I; Validated; Region: PRK06599
393115002513	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
393115002514	active site
393115002515	interdomain interaction site; other site
393115002516	putative metal-binding site [ion binding]; other site
393115002517	nucleotide binding site [chemical binding]; other site
393115002518	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
393115002519	domain I; other site
393115002520	DNA binding groove [nucleotide binding]
393115002521	phosphate binding site [ion binding]; other site
393115002522	domain II; other site
393115002523	domain III; other site
393115002524	nucleotide binding site [chemical binding]; other site
393115002525	catalytic site [active]
393115002526	domain IV; other site
393115002527	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
393115002528	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
393115002529	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
393115002530	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
393115002531	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
393115002532	P-loop; other site
393115002533	Magnesium ion binding site [ion binding]; other site
393115002534	ParB-like nuclease domain; Region: ParBc; cl02129
393115002535	KorB domain; Region: KorB; pfam08535
393115002536	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
393115002537	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
393115002538	catalytic triad [active]
393115002539	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
393115002540	active site
393115002541	catalytic triad [active]
393115002542	oxyanion hole [active]
393115002543	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
393115002544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
393115002545	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
393115002546	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
393115002547	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
393115002548	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115002549	active site
393115002550	HIGH motif; other site
393115002551	nucleotide binding site [chemical binding]; other site
393115002552	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
393115002553	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
393115002554	active site
393115002555	KMSKS motif; other site
393115002556	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
393115002557	tRNA binding surface [nucleotide binding]; other site
393115002558	anticodon binding site; other site
393115002559	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
393115002560	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
393115002561	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
393115002562	active site
393115002563	Riboflavin kinase; Region: Flavokinase; cl03312
393115002564	malate dehydrogenase; Provisional; Region: PRK13529
393115002565	Malic enzyme, N-terminal domain; Region: malic; pfam00390
393115002566	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002567	NAD(P) binding pocket [chemical binding]; other site
393115002568	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115002569	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115002570	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002571	Integrase core domain; Region: rve; cl01316
393115002572	Truncated early to prevent overlap with tRNA-val. Possible point mutation resulting in lost stop codon and run-through of sequence ORF ftt0921 hypothetical membrane protein
393115002573	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; cl01132
393115002574	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
393115002575	THUMP domain; Region: THUMP; cl12076
393115002576	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002577	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115002578	S-adenosylmethionine binding site [chemical binding]; other site
393115002579	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
393115002580	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
393115002581	putative active site [active]
393115002582	substrate binding site [chemical binding]; other site
393115002583	putative cosubstrate binding site; other site
393115002584	catalytic site [active]
393115002585	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
393115002586	substrate binding site [chemical binding]; other site
393115002587	glutathione synthetase; Provisional; Region: PRK05246
393115002588	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
393115002589	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115002590	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
393115002591	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
393115002592	inhibitor-cofactor binding pocket; inhibition site
393115002593	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002594	catalytic residue [active]
393115002595	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
393115002596	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
393115002597	Similar to Q98IH5 Beta-hydroxybutyrate dehydrogenase from Rhizobium loti (256 aa). FASTA: opt: 941 Z-score: 1009.9 E(): 2.1e-48 Smith-Waterman score: 941; 55.859 identity in 256 aa overlap. Contains an in-frame stop codon after aa 60 ORF ftt0929c
393115002598	Similar to Q8XR10 Probable acetoacetate decarboxylase from Ralstonia solanacearum (247 aa). FASTA: opt: 753 Z-score: 922.8 E(): 1.5e-43 Smith-Waterman score: 753; 56.158 identity in 203 aa overlap. CDS has no start codon due to a deletion at N-terminal ORF ftt0930c
393115002599	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
393115002600	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002601	putative substrate translocation pore; other site
393115002602	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
393115002603	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
393115002604	Similar to Q8EK84 BirA bifunctional protein from Shewanella oneidensis (319 aa). FASTA: opt: 576 Z-score: 667.4 E(): 2.5e-29 Smith-Waterman score: 576; 30.547 identity in 311 aa overlap. Contains a frameshift after aa 44 ORF ftt0933
393115002605	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002606	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002607	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
393115002608	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
393115002609	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
393115002610	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115002611	catalytic residue [active]
393115002612	biotin synthase; Region: bioB; TIGR00433
393115002613	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115002614	FeS/SAM binding site; other site
393115002615	Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149
393115002616	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
393115002617	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
393115002618	inhibitor-cofactor binding pocket; inhibition site
393115002619	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002620	catalytic residue [active]
393115002621	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
393115002622	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
393115002623	active site
393115002624	purine riboside binding site [chemical binding]; other site
393115002625	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
393115002626	CoenzymeA binding site [chemical binding]; other site
393115002627	subunit interaction site [polypeptide binding]; other site
393115002628	PHB binding site; other site
393115002629	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
393115002630	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
393115002631	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
393115002632	catalytic center binding site [active]
393115002633	ATP binding site [chemical binding]; other site
393115002634	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
393115002635	dihydropteroate synthase; Region: DHPS; TIGR01496
393115002636	substrate binding pocket [chemical binding]; other site
393115002637	dimer interface [polypeptide binding]; other site
393115002638	inhibitor binding site; inhibition site
393115002639	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
393115002640	active site
393115002641	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
393115002642	AMP-binding enzyme; Region: AMP-binding; cl15778
393115002643	aminodeoxychorismate synthase; Provisional; Region: PRK07508
393115002644	chorismate binding enzyme; Region: Chorismate_bind; cl10555
393115002645	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate...; Region: PLPDE_IV; cl00224
393115002646	substrate-cofactor binding pocket; other site
393115002647	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002648	catalytic residue [active]
393115002649	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
393115002650	Glutamine amidotransferase class-I; Region: GATase; pfam00117
393115002651	glutamine binding [chemical binding]; other site
393115002652	catalytic triad [active]
393115002653	Similar to Q83D24 Major facilitator family transporter from Coxiella burnetii (437 aa). FASTA: opt: 293 Z-score: 313.6 bits: 67.1 E(): 1.4e-09 Smith-Waterman score: 295; 22.963 identity in 405 aa overlap. Contains a frameshift after aa 171 ORF ftt0947c
393115002654	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Region: Tas; COG0667
393115002655	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
393115002656	active site
393115002657	catalytic tetrad [active]
393115002658	Similar to Q9KDX2 Hypothetical protein BH1089 from Bacillus halodurans (512 aa). FASTA: opt: 334 Z-score: 369.9 E(): 9.4e-13 Smith-Waterman score: 340; 26.603 identity in 421 aa overlap ORF ftt0949c
393115002659	Similar to Q9X202 Hypothetical protein TM1674 from Thermotoga maritima (237 aa). FASTA: opt: 319 Z-score: 397.2 E(): 3.1e-14 Smith-Waterman score: 319; 30.317 identity in 221 aa overlap. Contains a frameshift after aa 79 ORF ftt0950c
393115002660	GTP cyclohydrolase I; Provisional; Region: PLN03044
393115002661	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
393115002662	active site
393115002663	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
393115002664	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
393115002665	ATP binding site [chemical binding]; other site
393115002666	Mg++ binding site [ion binding]; other site
393115002667	motif III; other site
393115002668	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115002669	nucleotide binding region [chemical binding]; other site
393115002670	ATP-binding site [chemical binding]; other site
393115002671	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115002672	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
393115002673	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
393115002674	glutathione reductase; Validated; Region: PRK06116
393115002675	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115002676	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115002677	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
393115002678	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002679	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
393115002680	classical (c) SDRs; Region: SDR_c; cd05233
393115002681	NAD(P) binding site [chemical binding]; other site
393115002682	active site
393115002683	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
393115002684	putative active site [active]
393115002685	putative DNA binding site [nucleotide binding]; other site
393115002686	putative phosphate binding site [ion binding]; other site
393115002687	putative catalytic site [active]
393115002688	metal binding site A [ion binding]; metal-binding site
393115002689	putative AP binding site [nucleotide binding]; other site
393115002690	putative metal binding site B [ion binding]; other site
393115002691	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250
393115002692	active site
393115002693	Zn binding site [ion binding]; other site
393115002694	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
393115002695	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
393115002696	intracellular protease, PfpI family; Region: PfpI; TIGR01382
393115002697	potential catalytic triad [active]
393115002698	conserved cys residue [active]
393115002699	NeuB family; Region: NeuB; cl00496
393115002700	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
393115002701	signal recognition particle protein; Provisional; Region: PRK10867
393115002702	SRP54-type protein, helical bundle domain; Region: SRP54_N; cl03758
393115002703	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
393115002704	P loop; other site
393115002705	GTP binding site [chemical binding]; other site
393115002706	Signal peptide binding domain; Region: SRP_SPB; pfam02978
393115002707	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115002708	Predicted permeases [General function prediction only]; Region: COG0730; cl00498
393115002709	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
393115002710	rRNA binding site [nucleotide binding]; other site
393115002711	predicted 30S ribosome binding site; other site
393115002712	Similar to Q8ZQE7 Putative inner membrane protein from Salmonella typhimurium (299 aa). FASTA: opt: 439 Z-score: 520.3 E(): 3.9e-21 Smith-Waterman score: 462; 28.808 identity in 302 aa overlap. Contains a frameshift after aa 128. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0967c
393115002713	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
393115002714	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
393115002715	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002716	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl15357
393115002717	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115002718	FeS assembly SUF system regulator, gammaproteobacterial; Region: suf_reg_Xantho; TIGR02944
393115002719	Helix-turn-helix domains; Region: HTH; cl00088
393115002720	Uncharacterized protein family (UPF0051); Region: UPF0051; cl03223
393115002721	putative ABC transporter; Region: ycf24; CHL00085
393115002722	FeS assembly ATPase SufC; Region: sufC; TIGR01978
393115002723	ABC-type transport system involved in Fe-S cluster assembly, ATPase component.  Biosynthesis of iron-sulfur clusters (Fe-S) depends on multiprotein systems.  The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under...; Region: ABC_FeS_Assembly; cd03217
393115002724	Walker A/P-loop; other site
393115002725	ATP binding site [chemical binding]; other site
393115002726	Q-loop/lid; other site
393115002727	ABC transporter signature motif; other site
393115002728	Walker B; other site
393115002729	D-loop; other site
393115002730	H-loop/switch region; other site
393115002731	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
393115002732	Uncharacterized protein family (UPF0051); Region: UPF0051; cl03223
393115002733	Similar to Q826R2 Hypothetical protein from Streptomyces avermitilis (289 aa). FASTA: opt: 558 Z-score: 707.3 bits: 138.7 E(): 1.7e-31 Smith-Waterman score: 558; 34.351identity in 262 aa overlap. Contains an in-frame stop codon after aa 71 ORF ftt0974
393115002734	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
393115002735	catalytic residues [active]
393115002736	Helix-turn-helix domains; Region: HTH; cl00088
393115002737	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
393115002738	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
393115002739	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
393115002740	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115002741	catalytic residue [active]
393115002742	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
393115002743	PAS fold; Region: PAS_4; pfam08448
393115002744	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
393115002745	active site
393115002746	8-oxo-dGMP binding site [chemical binding]; other site
393115002747	nudix motif; other site
393115002748	metal binding site [ion binding]; metal-binding site
393115002749	Uncharacterized ACR, COG1678; Region: DUF179; cl00731
393115002750	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination.  HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD includes...; Region: RuvC_resolvase; cl00243
393115002751	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
393115002752	Transglutaminase-like superfamily; Region: Transglut_core; cl10469
393115002753	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
393115002754	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
393115002755	HIGH motif; other site
393115002756	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
393115002757	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
393115002758	active site
393115002759	KMSKS motif; other site
393115002760	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
393115002761	tRNA binding surface [nucleotide binding]; other site
393115002762	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
393115002763	Lipopolysaccharide-assembly; Region: LptE; cl01125
393115002764	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
393115002765	Mechanosensitive ion channel; Region: MS_channel; pfam00924
393115002766	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
393115002767	trimer interface [polypeptide binding]; other site
393115002768	active site
393115002769	cell division ATPase MinD, archaeal; Region: minD_arch; TIGR01969
393115002770	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
393115002771	Walker A motif; other site
393115002772	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115002773	Similar to Q81GK4 Cardiolipin synthetase from Bacillus cereus (514 aa). FASTA: opt: 830 Z-score: 1019.9 E(): 6.5e-49 Smith-Waterman score: 830; 31.198 identity in 484 aa overlap. Contains frameshift and lacks start codon. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0996
393115002774	cardiolipin synthetase; Reviewed; Region: PRK12452
393115002775	Putative catalytic domain, repeat 1, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar1_1; cd09156
393115002776	putative active site [active]
393115002777	catalytic site [active]
393115002778	Putative catalytic domain, repeat 2, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar1_2; cd09162
393115002779	putative active site [active]
393115002780	catalytic site [active]
393115002781	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115002782	Similar to Q83BJ7 Transporter, ZIP family from Coxiella burnetii (261 aa). FASTA: opt: 365 Z-score: 455.0 E(): 1.9e-17 Smith-Waterman score: 365; 32.593 identity in 270 aa overlap. Contains a frameshfit after aa 73 ORF ftt0999c
393115002783	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
393115002784	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115002785	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; cl08458
393115002786	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
393115002787	metal binding site 2 [ion binding]; metal-binding site
393115002788	putative DNA binding helix; other site
393115002789	metal binding site 1 [ion binding]; metal-binding site
393115002790	dimer interface [polypeptide binding]; other site
393115002791	structural Zn2+ binding site [ion binding]; other site
393115002792	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
393115002793	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
393115002794	putative tRNA-binding site [nucleotide binding]; other site
393115002795	B3/4 domain; Region: B3_4; cl11458
393115002796	tRNA synthetase B5 domain; Region: B5; cl08394
393115002797	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
393115002798	dimer interface [polypeptide binding]; other site
393115002799	motif 1; other site
393115002800	motif 3; other site
393115002801	motif 2; other site
393115002802	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; cl08386
393115002803	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
393115002804	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
393115002805	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
393115002806	dimer interface [polypeptide binding]; other site
393115002807	motif 1; other site
393115002808	active site
393115002809	motif 2; other site
393115002810	motif 3; other site
393115002811	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
393115002812	EamA-like transporter family; Region: EamA; cl01037
393115002813	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115002814	MFS/sugar transport protein; Region: MFS_2; pfam13347
393115002815	MFS/sugar transport protein; Region: MFS_2; pfam13347
393115002816	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
393115002817	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
393115002818	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
393115002819	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl15761
393115002820	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
393115002821	Similar to Q8EEM6 Bax protein,putative (255 aa). FASTA: opt: 393 Z-score: 458.7 E(): 1.1e-17 Smith-Waterman score: 393; 34.906 identity in 212 aa overlap. Contains a frameshift after aa 53. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1012
393115002822	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
393115002823	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115002824	Walker A motif; other site
393115002825	ATP binding site [chemical binding]; other site
393115002826	Walker B motif; other site
393115002827	arginine finger; other site
393115002828	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
393115002829	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
393115002830	classical (c) SDRs; Region: SDR_c; cd05233
393115002831	NAD(P) binding site [chemical binding]; other site
393115002832	active site
393115002833	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
393115002834	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
393115002835	active site
393115002836	catalytic triad [active]
393115002837	oxyanion hole [active]
393115002838	switch loop; other site
393115002839	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
393115002840	putative active site pocket [active]
393115002841	dimerization interface [polypeptide binding]; other site
393115002842	putative catalytic residue [active]
393115002843	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
393115002844	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
393115002845	TPP-binding site; other site
393115002846	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
393115002847	PYR/PP interface [polypeptide binding]; other site
393115002848	dimer interface [polypeptide binding]; other site
393115002849	TPP binding site [chemical binding]; other site
393115002850	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
393115002851	GMP synthase; Reviewed; Region: guaA; PRK00074
393115002852	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
393115002853	AMP/PPi binding site [chemical binding]; other site
393115002854	candidate oxyanion hole; other site
393115002855	catalytic triad [active]
393115002856	potential glutamine specificity residues [chemical binding]; other site
393115002857	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
393115002858	ATP Binding subdomain [chemical binding]; other site
393115002859	Ligand Binding sites [chemical binding]; other site
393115002860	Dimerization subdomain; other site
393115002861	Amino acid permease; Region: AA_permease_2; pfam13520
393115002862	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
393115002863	PseudoU_synth_EcTruA: Pseudouridine synthase, Escherichia coli TruA like. This group consists of eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA, Pseudomonas aeruginosa truA and human pseudouridine synthase-like 1 (PUSL1); Region: PseudoU_synth_EcTruA; cd02570
393115002864	dimerization interface 3.5A [polypeptide binding]; other site
393115002865	active site
393115002866	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
393115002867	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl12031
393115002868	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
393115002869	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
393115002870	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
393115002871	The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in...; Region: ABC_YhbG; cd03218
393115002872	Walker A/P-loop; other site
393115002873	ATP binding site [chemical binding]; other site
393115002874	Q-loop/lid; other site
393115002875	ABC transporter signature motif; other site
393115002876	Walker B; other site
393115002877	D-loop; other site
393115002878	H-loop/switch region; other site
393115002879	OstA-like protein; Region: OstA; cl00844
393115002880	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
393115002881	Low specificity phosphatase (HAD superfamily) [General function prediction only]; Region: COG1778
393115002882	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115002883	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
393115002884	dimer interface [polypeptide binding]; other site
393115002885	substrate binding site [chemical binding]; other site
393115002886	metal binding sites [ion binding]; metal-binding site
393115002887	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
393115002888	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
393115002889	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; cl06814
393115002890	Protein of unknown function (DUF493); Region: DUF493; cl01102
393115002891	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
393115002892	Similar to Q8FKS3 Putative oligogalacturonide transporter from Escherichia coli O6 (504 aa). FASTA: opt: 724 Z-score: 813.6 E(): 2e-37 Smith-Waterman score: 763; 30.675 identity in 489 aa overlap. Contains as in-frame stop codon ORF ftt1032
393115002893	Similar to Q8ZKT9 Putative alpha-xylosidase from Salmonella typhimurium (678 aa). FASTA: opt: 2551 Z-score: 3058.2 E(): 1.9e-162 Smith-Waterman score: 2551; 54.364 identity in 653 aa overlap. Contains an in-frame stop codon
393115002894	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
393115002895	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115002896	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
393115002897	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
393115002898	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
393115002899	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
393115002900	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
393115002901	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
393115002902	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
393115002903	DNA binding residues [nucleotide binding]
393115002904	CHC2 zinc finger; Region: zf-CHC2; cl15369
393115002905	DNA primase; Validated; Region: dnaG; PRK05667
393115002906	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
393115002907	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
393115002908	active site
393115002909	metal binding site [ion binding]; metal-binding site
393115002910	interdomain interaction site; other site
393115002911	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
393115002912	GatB domain; Region: GatB_Yqey; cl11497
393115002913	Ribosomal protein S21; Region: Ribosomal_S21; cl00529
393115002914	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027
393115002915	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl01009
393115002916	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic 'goose-type' lysozymes (GEWL).  LTs catalyze...; Region: LT_GEWL; cd00254
393115002917	N-acetyl-D-glucosamine binding site [chemical binding]; other site
393115002918	catalytic residue [active]
393115002919	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
393115002920	active site
393115002921	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
393115002922	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
393115002923	Ligand Binding Site [chemical binding]; other site
393115002924	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
393115002925	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
393115002926	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; cl11587
393115002927	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
393115002928	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
393115002929	substrate binding pocket [chemical binding]; other site
393115002930	chain length determination region; other site
393115002931	substrate-Mg2+ binding site; other site
393115002932	catalytic residues [active]
393115002933	aspartate-rich region 1; other site
393115002934	active site lid residues [active]
393115002935	aspartate-rich region 2; other site
393115002936	PQ loop repeat; Region: PQ-loop; cl12056
393115002937	Similar to CYSC_CLOAB (Q97MT8) Adenylylsulfate kinase from Clostridium acetobutylicum (200 aa). FASTA: opt: 732 Z-score: 905.0 E(): 1.6e-42 Smith-Waterman score: 732; 59.669 identity in 181 aa overlap. Some homologs have cysN and cysC concatenated (cysNC). No start codon due to deletion at N-terminal
393115002938	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
393115002939	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
393115002940	CysD dimerization site [polypeptide binding]; other site
393115002941	G1 box; other site
393115002942	putative GEF interaction site [polypeptide binding]; other site
393115002943	GTP/Mg2+ binding site [chemical binding]; other site
393115002944	Switch I region; other site
393115002945	G2 box; other site
393115002946	G3 box; other site
393115002947	Switch II region; other site
393115002948	G4 box; other site
393115002949	G5 box; other site
393115002950	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
393115002951	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
393115002952	Similar to Q9ZIX7, putative transposase from Haemophilus gallinarum (216 aa). FASTA: opt: 566 Z-score: 710.4 E(): 1e-31 Smith-Waterman score: 566; 42.056 identity in 214 aa overlap. Stop codon at aa position 99 Identical to FTF1792c. However, there is a mutation in the IRR of this copy that abolishes the stop codon that is present in FTF1792c. This generates a hypothetical protein of an extra 5 aa in this instance. ORF ftt1053c
393115002953	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
393115002954	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
393115002955	preprotein translocase subunit SecA; Validated; Region: secA; CHL00122
393115002956	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
393115002957	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115002958	RNA binding surface [nucleotide binding]; other site
393115002959	PseudoU_synth_RluB: Pseudouridine synthase, Escherichia coli RluB like. This group is comprised of bacterial and eukaryotic proteins similar to E. coli RluB. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to...; Region: PseudoU_synth_RluB; cd02556
393115002960	probable active site [active]
393115002961	type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521
393115002962	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
393115002963	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115002964	FeS/SAM binding site; other site
393115002965	replicative DNA helicase; Region: DnaB; TIGR00665
393115002966	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
393115002967	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
393115002968	Walker A motif; other site
393115002969	ATP binding site [chemical binding]; other site
393115002970	Walker B motif; other site
393115002971	DNA binding loops [nucleotide binding]
393115002972	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
393115002973	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
393115002974	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
393115002975	Ribosomal protein S18; Region: Ribosomal_S18; cl00373
393115002976	Ribosomal protein S6; Region: Ribosomal_S6; cl00414
393115002977	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; cl00433
393115002978	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
393115002979	catalytic core [active]
393115002980	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002981	Integrase core domain; Region: rve; cl01316
393115002982	Similar to Q8RG91 Type III restriction-modification system restriction subunit from Fusobacterium nucleatum (subsp. nucleatum) (997 aa). FASTA: opt: 2647 Z-score: 2741.6 E(): 7.4e-145 Smith-Waterman score: 2729; 46.356 identity in 1029 aa overlap.
393115002983	Abi-like protein; Region: Abi_2; cl01988
393115002984	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
393115002985	Similar to EAA25085 ATP-dependent helicase HEPA from Fusobacterium nucleatum subsp. vincentii ATCC 49256 (1070 aa). FASTA: opt: 3128 Z-score: 3170.3 E(): 9.7e-169 Smith-Waterman score: 3128; 50.250 identity in 1001 aa overlap. Contains a frameshift after aa 974. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1070c
393115002986	Antirestriction protein (ArdA); Region: ArdA; cl01953
393115002987	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115002988	Integrase core domain; Region: rve; cl01316
393115002989	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
393115002990	non-specific DNA binding site [nucleotide binding]; other site
393115002991	salt bridge; other site
393115002992	sequence-specific DNA binding site [nucleotide binding]; other site
393115002993	HipA N-terminal domain; Region: Couple_hipA; cl11853
393115002994	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
393115002995	HipA-like N-terminal domain; Region: HipA_N; pfam07805
393115002996	HipA-like C-terminal domain; Region: HipA_C; pfam07804
393115002997	Putative exonuclease, RdgC; Region: RdgC; cl01122
393115002998	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
393115002999	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
393115003000	active site residue [active]
393115003001	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
393115003002	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115003003	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115003004	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
393115003005	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115003006	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115003007	Family description; Region: UvrD_C_2; cl15862
393115003008	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
393115003009	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
393115003010	Isochorismatase family; Region: Isochorismatase; pfam00857
393115003011	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
393115003012	catalytic triad [active]
393115003013	conserved cis-peptide bond; other site
393115003014	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
393115003015	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
393115003016	Isochorismatase family; Region: Isochorismatase; pfam00857
393115003017	catalytic triad [active]
393115003018	conserved cis-peptide bond; other site
393115003019	transaldolase-like protein; Provisional; Region: PTZ00411
393115003020	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
393115003021	active site
393115003022	dimer interface [polypeptide binding]; other site
393115003023	catalytic residue [active]
393115003024	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
393115003025	interface (dimer of trimers) [polypeptide binding]; other site
393115003026	Substrate-binding/catalytic site; other site
393115003027	Zn-binding sites [ion binding]; other site
393115003028	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
393115003029	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
393115003030	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of...; Region: AlaRS_core; cd00673
393115003031	motif 1; other site
393115003032	active site
393115003033	motif 2; other site
393115003034	motif 3; other site
393115003035	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469
393115003036	Similar to REP_BUCAI (P57654) ATP-dependent DNA helicase rep from Buchnera aphidicola (subsp. Acyrthosiphon pisum) (Acyrthosiphon pisum symbiotic bacterium) (645 aa). FASTA: opt: 662 Z-score: 713.3 bits: 142.3 E(): 7.7e-32 Smith-Waterman score: 662; 28.502 identity in 621 aa overlap. Contains a frameshift after aa 167. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift. ORF ftt1098c
393115003037	Oligomerisation domain; Region: Oligomerisation; cl00519
393115003038	Similar to YJES_ECOLI (P39288) Putative electron transport protein from Escherichia coli (379 aa). FASTA: opt: 611 Z-score: 746.8 E(): 1e-33 Smith-Waterman score: 999; 45.938 identity in 357 aa overlap. Contains 2 frameshifts after aa 119 and 176. Both frameshifts occur at heptanucleotide sequences and so could be part of a programmed translational frameshifts
393115003039	Similar to O32828 Macrophage infectivity potentiator from Legionella oakridgensis (234 aa). FASTA: opt: 191 Z-score: 250.2 E(): 4.8e-06 Smith-Waterman score: 191; 35.484identity in 93 aa overlap. Deletion at carboxy terminal truncates this protein ORF ftt1102
393115003040	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
393115003041	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
393115003042	catalytic residues [active]
393115003043	Similar to Q9CKS3 Bcr from Pasteurella multocida (399 aa). FASTA: opt: 568 Z-score: 616.5 E(): 1.9e-26 Smith-Waterman score: 568; 30.518 identity in 367 aa overlap. Contains a frameshift after aa 85 Putative drug transport protein.
393115003044	bifunctional methionine sulfoxide reductase B/A protein; Provisional; Region: PRK05550
393115003045	methionine sulfoxide reductase B; Provisional; Region: PRK00222; cl15841
393115003046	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
393115003047	TspO/MBR family; Region: TspO_MBR; cl01379
393115003048	Similar to Q8L2B3 (Q8L2B3) Choline transporter from Proteus vulgaris (665 aa). FASTA: opt: 1958 Z-score: 2178.1 E(): 2e-113 Smith-Waterman score: 2111; 47.546 identity in 652 aa overlap. Contains a frameshift after aa 133. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115003049	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
393115003050	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
393115003051	SpoU rRNA Methylase family; Region: SpoU_methylase; cl00362
393115003052	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
393115003053	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
393115003054	active site
393115003055	Transposase domain (DUF772); Region: DUF772; cl15789
393115003056	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115003057	Transposase domain (DUF772); Region: DUF772; cl15789
393115003058	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
393115003059	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
393115003060	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
393115003061	DNA binding residues [nucleotide binding]
393115003062	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
393115003063	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
393115003064	Protein export membrane protein; Region: SecD_SecF; cl14618
393115003065	SecD export protein N-terminal TM region; Region: SecD-TM1; cl08136
393115003066	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
393115003067	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
393115003068	Protein export membrane protein; Region: SecD_SecF; cl14618
393115003069	Preprotein translocase subunit; Region: YajC; cl00806
393115003070	Isochorismatase family; Region: Isochorismatase; pfam00857
393115003071	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
393115003072	catalytic triad [active]
393115003073	conserved cis-peptide bond; other site
393115003074	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
393115003075	Helix-turn-helix domains; Region: HTH; cl00088
393115003076	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115003077	dimerization interface [polypeptide binding]; other site
393115003078	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
393115003079	tRNA-guanine transglycosylases, various specificities; Region: tgt_general; TIGR00449
393115003080	Similar to Q9JTA5 Insertion element IS1016 transposase (fragment) from Neisseria meningitidis (serogroup A) (151 aa). FASTA: opt: 364 Z-score: 568.7 E(): 8.7e-24 Smith-Waterman score: 364; 77.778identity in 72 aa overlap. FTF1121 is a fragment of FTF1583. ORF ftt1121
393115003081	Protein of unknown function (DUF3281); Region: DUF3281; pfam11685
393115003082	Protein of unknown function (DUF3281); Region: DUF3281; pfam11685
393115003083	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
393115003084	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
393115003085	MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport.  Other members of this system include the MetP permease and  the MetQ substrate binding protein.  ABC...; Region: ABC_MetN_methionine_transporter; cd03258
393115003086	Walker A/P-loop; other site
393115003087	ATP binding site [chemical binding]; other site
393115003088	Q-loop/lid; other site
393115003089	ABC transporter signature motif; other site
393115003090	Walker B; other site
393115003091	D-loop; other site
393115003092	H-loop/switch region; other site
393115003093	NIL domain; Region: NIL; cl09633
393115003094	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115003095	dimer interface [polypeptide binding]; other site
393115003096	conserved gate region; other site
393115003097	ABC-ATPase subunit interface; other site
393115003098	NMT1-like family; Region: NMT1_2; cl15260
393115003099	Transmembrane amino acid transporter protein; Region: Aa_trans; cl15776
393115003100	aromatic amino acid transport protein; Region: araaP; TIGR00837
393115003101	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
393115003102	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
393115003103	active site residue [active]
393115003104	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
393115003105	active site residue [active]
393115003106	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
393115003107	homotrimer interaction site [polypeptide binding]; other site
393115003108	zinc binding site [ion binding]; other site
393115003109	CDP-binding sites; other site
393115003110	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115003111	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115003112	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115003113	cyanophycin synthetase; Provisional; Region: PRK14016
393115003114	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115003115	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115003116	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115003117	Similar to Q97D94 Competence-damage inducible protein, CINA, from Clostridium acetobutylicum (411 aa). FASTA: opt: 398 Z-score: 508.8 E(): 1.9e-20 Smith-Waterman score: 398; 31.687 identity in 243 aa overlap. Appears to be a deletion at carboxy terminus ORF ftt1131
393115003118	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
393115003119	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
393115003120	active site
393115003121	catalytic site [active]
393115003122	type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538
393115003123	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
393115003124	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
393115003125	Walker A motif; other site
393115003126	ATP binding site [chemical binding]; other site
393115003127	Walker B motif; other site
393115003128	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
393115003129	Type II secretion system (T2SS), protein F; Region: T2SF; cl00906
393115003130	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
393115003131	Type II secretion system (T2SS), protein F; Region: T2SF; cl00906
393115003132	Similar to Q8EAU9 Conserved hypothetical protein from Shewanella oneidensis (390 aa). FASTA: opt: 1502 Z-score: 1709.5 E(): 2.3e-87 Smith-Waterman score: 1502; 57.584 identity in 389 aa overlap. Contains two frameshifts after aa 20 and 291. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1135c
393115003133	ferrochelatase; Reviewed; Region: hemH; PRK00035
393115003134	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
393115003135	C-terminal domain interface [polypeptide binding]; other site
393115003136	active site
393115003137	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
393115003138	active site
393115003139	N-terminal domain interface [polypeptide binding]; other site
393115003140	Similar to Q83CE4 Deoxyribodipyrimidine photolyase-class I from Coxiella burnetii (472 aa). FASTA: opt: 1369 Z-score: 1649.6 E(): 5.4e-84 Smith-Waterman score: 1369; 43.103identity in 464 aa overlap. Contains a frameshift after aa 86
393115003141	Similar to Q8PW11 Hypothetical protein MM1793 from Methanosarcina mazei (Methanosarcina frisia) (135 aa). FASTA: opt: 328 Z-score: 442.8 E(): 9e-17 Smith-Waterman score: 328; 50.000 identity in 96 aa overlap. CDS interrupted by an ISFtu1 element ORF ftt1141
393115003142	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003143	Integrase core domain; Region: rve; cl01316
393115003144	Similar to Q9RYF4 Oxidoreductase, short-chain dehydrogenase family from Deinococcus radiodurans (390 aa). FASTA: opt: 913 Z-score: 1084.4 E(): 1.6e-52 Smith-Waterman score: 913; 50.360 identity in 278 aa overlap. Contains a frameshift after aa 153. ameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1144
393115003145	ChaB; Region: ChaB; cl01887
393115003146	Similar to EAA24361 (EAA24361) Aldose 1-epimerase (EC 5.1.3.3) from Fusobacterium nucleatum subsp. vincentii ATCC 49256 (330 aa). FASTA: opt: 574 Z-score: 714.1 E(): 6.9e-32 Smith-Waterman score: 574; 34.783 identity in 322 aa overlap. Contains a frameshift after aa 231, possibly caused by an internal deletion
393115003147	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
393115003148	Flavoprotein; Region: Flavoprotein; cl08021
393115003149	DNA / pantothenate metabolism flavoprotein; Region: DFP; cl04410
393115003150	benzoate transport; Region: 2A0115; TIGR00895
393115003151	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003152	putative substrate translocation pore; other site
393115003153	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
393115003154	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: PRK11904
393115003155	Proline dehydrogenase; Region: Pro_dh; cl03282
393115003156	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
393115003157	Glutamate binding site [chemical binding]; other site
393115003158	NAD binding site [chemical binding]; other site
393115003159	catalytic residues [active]
393115003160	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
393115003161	NAD(P) binding site [chemical binding]; other site
393115003162	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
393115003163	Flavinator of succinate dehydrogenase; Region: Sdh5; cl01110
393115003164	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
393115003165	active site
393115003166	dimer interface [polypeptide binding]; other site
393115003167	metal binding site [ion binding]; metal-binding site
393115003168	shikimate kinase; Reviewed; Region: aroK; PRK00131
393115003169	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
393115003170	ADP binding site [chemical binding]; other site
393115003171	magnesium binding site [ion binding]; other site
393115003172	putative shikimate binding site; other site
393115003173	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
393115003174	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
393115003175	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
393115003176	Pilus assembly protein, PilP; Region: PilP; cl01235
393115003177	Pilus assembly protein, PilO; Region: PilO; cl01234
393115003178	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
393115003179	adenylate kinase; Reviewed; Region: adk; PRK00279
393115003180	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
393115003181	AMP-binding site [chemical binding]; other site
393115003182	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
393115003183	Similar to Q88DT2 D-lactate dehydrogenase, putative from Pseudomonas putida (strain KT2440) (936 aa). FASTA: opt: 1665 Z-score: 1856.9 E(): 1.5e-95 Smith-Waterman score: 2125; 37.763identity in 903 aa overlap. Contains an in-frame stop codon after aa 312 and a frameshift after aa 431 ORF ftt1162c
393115003184	GTPase Era; Reviewed; Region: era; PRK00089
393115003185	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
393115003186	G1 box; other site
393115003187	GTP/Mg2+ binding site [chemical binding]; other site
393115003188	Switch I region; other site
393115003189	G2 box; other site
393115003190	Switch II region; other site
393115003191	G3 box; other site
393115003192	G4 box; other site
393115003193	G5 box; other site
393115003194	aspartate aminotransferase; Provisional; Region: PRK05764
393115003195	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
393115003196	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115003197	homodimer interface [polypeptide binding]; other site
393115003198	catalytic residue [active]
393115003199	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
393115003200	putative active site [active]
393115003201	putative dimer interface [polypeptide binding]; other site
393115003202	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl14000
393115003203	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
393115003204	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
393115003205	active site
393115003206	dimer interface [polypeptide binding]; other site
393115003207	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
393115003208	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
393115003209	GTP/Mg2+ binding site [chemical binding]; other site
393115003210	G4 box; other site
393115003211	G5 box; other site
393115003212	G1 box; other site
393115003213	Switch I region; other site
393115003214	G2 box; other site
393115003215	G3 box; other site
393115003216	Switch II region; other site
393115003217	Sel1 repeat; Region: Sel1; cl02723
393115003218	HsdM N-terminal domain; Region: HsdM_N; pfam12161
393115003219	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
393115003220	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003221	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; Region: CSP_CDS; cd04458
393115003222	DNA-binding site [nucleotide binding]; DNA binding site
393115003223	RNA-binding motif; other site
393115003224	Similar to CAD76983 Type I restriction enzyme EcoEI specificity protein from Rhodopirellula baltica (550 aa). FASTA: opt: 492 Z-score: 583.4 E(): 1.3e-24 Smith-Waterman score: 492; 42.929 identity in 198 aa overlap. Contains an in-frame stop codon at aa 48 and a frameshift at aa 133
393115003225	Similar to Q8RIX1 HsdR from Campylobacter jejuni (769 aa). FASTA: opt: 2132 Z-score: 2421.3 E(): 5.6e-127 Smith-Waterman score: 2642; 53.402 identity in 779 aa overlap. Contains a frameshift after aa 61 and an in-frame stop codon after aa 208
393115003226	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
393115003227	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
393115003228	G1 box; other site
393115003229	putative GEF interaction site [polypeptide binding]; other site
393115003230	GTP/Mg2+ binding site [chemical binding]; other site
393115003231	Switch I region; other site
393115003232	G2 box; other site
393115003233	G3 box; other site
393115003234	Switch II region; other site
393115003235	G4 box; other site
393115003236	G5 box; other site
393115003237	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
393115003238	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
393115003239	Similar to Q8EXW1 Conserved hypothetical protein from Leptospira interrogans (250 aa). FASTA: opt: 528 Z-score: 655.2 E(): 1.3e-28 Smith-Waterman score: 528; 34.711 identity in 242 aa overlap. Contains an in-frame stop codon after aa 107 ORF ftt1180
393115003240	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
393115003241	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
393115003242	Similar to Q9Z674 Lipoprotein from Zymomonas mobilis (256 aa). FASTA: opt: 348 Z-score: 428.0 E(): 6e-16 Smith-Waterman score: 348; 33.333 identity in 234 aa overlap. Contains an in-frame stop codon
393115003243	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
393115003244	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003245	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cl15768
393115003246	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
393115003247	putative coenzyme Q binding site [chemical binding]; other site
393115003248	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
393115003249	SmpB-tmRNA interface; other site
393115003250	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
393115003251	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
393115003252	Ligand Binding Site [chemical binding]; other site
393115003253	Similar to Q87YJ5 Major facilitator family transporter from Pseudomonas syringae (pv. tomato) (445 aa). FASTA: opt: 858 Z-score: 886.6 E(): 1.7e-41 Smith-Waterman score: 858; 34.123 identity in 422 aa overlap. Contains 2 frameshifts after aa 150 and 196 ORF ftt1189c
393115003254	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
393115003255	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
393115003256	generic binding surface II; other site
393115003257	generic binding surface I; other site
393115003258	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
393115003259	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
393115003260	metal binding site [ion binding]; metal-binding site
393115003261	dimer interface [polypeptide binding]; other site
393115003262	Similar to Q9RSX6 Hypothetical protein DR1993 from Deinococcus radiodurans (274 aa). FASTA: opt: 488 Z-score: 621.6 E(): 9.8e-27 Smith-Waterman score: 488; 32.500 identity in 280 aa overlap. Contains a frameshfit after aa 295 ORF ftt1192c
393115003263	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
393115003264	putative dimer interface [polypeptide binding]; other site
393115003265	putative active site [active]
393115003266	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; cl00980
393115003267	Similar to Q88JG1 Conserved hypothetical protein from Pseudomonas putida (strain KT2440) (469 aa). FASTA: opt: 1631 Z-score: 1944.7 E(): 2e-100 Smith-Waterman score: 1631; 52.903 identity in 465 aa overlap. Contains a frameshift at aa 59. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1195c
393115003268	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115003269	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
393115003270	Restriction endonuclease; Region: Mrr_cat; cl00516
393115003271	excinuclease ABC subunit B; Provisional; Region: PRK05298
393115003272	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115003273	ATP binding site [chemical binding]; other site
393115003274	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115003275	nucleotide binding region [chemical binding]; other site
393115003276	ATP-binding site [chemical binding]; other site
393115003277	Ultra-violet resistance protein B; Region: UvrB; pfam12344
393115003278	UvrB/uvrC motif; Region: UVR; pfam02151
393115003279	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
393115003280	active site
393115003281	substrate binding site [chemical binding]; other site
393115003282	catalytic site [active]
393115003283	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
393115003284	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003285	NAD(P) binding site [chemical binding]; other site
393115003286	active site
393115003287	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115003288	Helix-turn-helix domains; Region: HTH; cl00088
393115003289	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115003290	putative effector binding pocket; other site
393115003291	dimerization interface [polypeptide binding]; other site
393115003292	Fusaric acid resistance protein-like; Region: FUSC_2; cl15844
393115003293	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
393115003294	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003295	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
393115003296	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
393115003297	tetramer (dimer of dimers) interface [polypeptide binding]; other site
393115003298	active site
393115003299	dimer interface [polypeptide binding]; other site
393115003300	Similar to Q8EAQ3 Peptidase, M13 family from Shewanella oneidensis (694 aa). FASTA: opt: 1942 Z-score: 2116.8 E(): 4.7e-110 Smith-Waterman score: 1942; 44.688 identity in 640 aa overlap. This CDS lacks a start codon due to an interruption of an ISFtu1 element at the N-terminal end ORF ftt1209c
393115003301	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003302	Integrase core domain; Region: rve; cl01316
393115003303	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
393115003304	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
393115003305	dimer interface [polypeptide binding]; other site
393115003306	active site
393115003307	metal binding site [ion binding]; metal-binding site
393115003308	glutathione binding site [chemical binding]; other site
393115003309	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; cl00756
393115003310	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115003311	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
393115003312	active site
393115003313	motif I; other site
393115003314	motif II; other site
393115003315	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115003316	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
393115003317	Queuosine biosynthesis protein; Region: Queuosine_synth; cl00523
393115003318	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003319	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
393115003320	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003321	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
393115003322	Uncharacterized protein family (UPF0149); Region: UPF0149; cl01173
393115003323	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; cl00360
393115003324	BolA-like protein; Region: BolA; cl00386
393115003325	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115003326	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115003327	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
393115003328	Recombination protein O N terminal; Region: RecO_N; cl15812
393115003329	Recombination protein O C terminal; Region: RecO_C; pfam02565
393115003330	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
393115003331	cysteine desulfurase DndA; Region: DNA_S_dndA; TIGR03235
393115003332	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115003333	catalytic residue [active]
393115003334	ribonuclease E; Reviewed; Region: rne; PRK10811
393115003335	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
393115003336	homodimer interface [polypeptide binding]; other site
393115003337	oligonucleotide binding site [chemical binding]; other site
393115003338	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
393115003339	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
393115003340	dimerization interface [polypeptide binding]; other site
393115003341	active site
393115003342	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
393115003343	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003344	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
393115003345	L-serine binding site [chemical binding]; other site
393115003346	ACT domain interface; other site
393115003347	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
393115003348	Ligand Binding Site [chemical binding]; other site
393115003349	B3/4 domain; Region: B3_4; cl11458
393115003350	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003351	Integrase core domain; Region: rve; cl01316
393115003352	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115003353	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115003354	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
393115003355	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
393115003356	active site
393115003357	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
393115003358	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
393115003359	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
393115003360	Ligand binding site; other site
393115003361	metal-binding site
393115003362	Protein of unknown function (DUF615); Region: DUF615; cl01147
393115003363	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
393115003364	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
393115003365	dimer interface [polypeptide binding]; other site
393115003366	glycine-pyridoxal phosphate binding site [chemical binding]; other site
393115003367	active site
393115003368	folate binding site [chemical binding]; other site
393115003369	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
393115003370	FAD binding domain; Region: FAD_binding_4; pfam01565
393115003371	Berberine and berberine like; Region: BBE; pfam08031
393115003372	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
393115003373	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
393115003374	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115003375	RNA binding surface [nucleotide binding]; other site
393115003376	PseudoU_synth_RsuA/RluD: Pseudouridine synthase, RsuA/RluD family. This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and...; Region: PseudoU_synth_RluCD_like; cd02869
393115003377	active site
393115003378	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
393115003379	Permease; Region: Permease; cl00510
393115003380	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
393115003381	ABC (ATP-binding cassette) transport system involved in resistant to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex...; Region: ABC_Org_Solvent_Resistant; cd03261
393115003382	Walker A/P-loop; other site
393115003383	ATP binding site [chemical binding]; other site
393115003384	Q-loop/lid; other site
393115003385	ABC transporter signature motif; other site
393115003386	Walker B; other site
393115003387	D-loop; other site
393115003388	H-loop/switch region; other site
393115003389	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
393115003390	mce related protein; Region: MCE; pfam02470
393115003391	Protein of unknown function (DUF445); Region: DUF445; pfam04286
393115003392	RNA methyltransferase; Region: Methyltrans_RNA; pfam04452
393115003393	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385; cl00611
393115003394	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
393115003395	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003396	putative substrate translocation pore; other site
393115003397	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl11420
393115003398	Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059
393115003399	AMP-binding enzyme; Region: AMP-binding; cl15778
393115003400	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
393115003401	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
393115003402	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
393115003403	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003404	putative substrate translocation pore; other site
393115003405	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
393115003406	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115003407	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115003408	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
393115003409	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
393115003410	NAD synthase; Region: NAD_synthase; pfam02540
393115003411	homodimer interface [polypeptide binding]; other site
393115003412	NAD binding pocket [chemical binding]; other site
393115003413	ATP binding pocket [chemical binding]; other site
393115003414	Mg binding site [ion binding]; other site
393115003415	active-site loop [active]
393115003416	Similar to Q8Y1Q6 Putative TRP repressor binding protein homolog from Ralstonia solanacearum (Pseudomonas solanacearum) (190 aa). FASTA: opt: 526 Z-score: 661.0 E(): 6.3e-29 Smith-Waterman score: 526; 45.503 identity in 189 aa overlap. Contains 2 frameshifts after aa 47 and 85 ORF ftt1261c
393115003417	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003418	Integrase core domain; Region: rve; cl01316
393115003419	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
393115003420	ISFtu2, fragment. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa) in 154aa overlap. ISFtu2 ORF Caboxy terminal only
393115003421	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003422	Integrase core domain; Region: rve; cl01316
393115003423	Pirin-related protein [General function prediction only]; Region: COG1741
393115003424	Cupin domain; Region: Cupin_2; cl09118
393115003425	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115003426	Helix-turn-helix domains; Region: HTH; cl00088
393115003427	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115003428	putative effector binding pocket; other site
393115003429	dimerization interface [polypeptide binding]; other site
393115003430	chaperone protein DnaJ; Provisional; Region: PRK10767
393115003431	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
393115003432	HSP70 interaction site [polypeptide binding]; other site
393115003433	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
393115003434	substrate binding site [polypeptide binding]; other site
393115003435	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
393115003436	Zn binding sites [ion binding]; other site
393115003437	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
393115003438	dimer interface [polypeptide binding]; other site
393115003439	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
393115003440	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
393115003441	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
393115003442	dimer interface [polypeptide binding]; other site
393115003443	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
393115003444	Membrane-bound lytic murein transglycosylase [Cell envelope biogenesis, outer membrane]; Region: MltA; COG2821
393115003445	MltA specific insert domain; Region: MltA; cl08398
393115003446	3D domain; Region: 3D; cl01439
393115003447	Protoporphyrinogen oxidase [Coenzyme metabolism]; Region: HemY; COG1232
393115003448	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
393115003449	23S rRNA interface [nucleotide binding]; other site
393115003450	L3 interface [polypeptide binding]; other site
393115003451	Ribosomal protein S9/S16; Region: Ribosomal_S9; cl00334
393115003452	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115003453	Stringent starvation protein B; Region: SspB; cl01120
393115003454	Sodium:solute symporter family; Region: SSF; cl00456
393115003455	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
393115003456	RNA/DNA hybrid binding site [nucleotide binding]; other site
393115003457	active site
393115003458	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
393115003459	SpoU rRNA Methylase family; Region: SpoU_methylase; cl00362
393115003460	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
393115003461	active site
393115003462	phosphorylation site [posttranslational modification]
393115003463	RaiA ('ribosome-associated inhibitor A', also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site; Region: RaiA; cd00552
393115003464	30S subunit binding site; other site
393115003465	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
393115003466	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
393115003467	trmE is a tRNA modification GTPase; Region: trmE; cd04164
393115003468	G1 box; other site
393115003469	GTP/Mg2+ binding site [chemical binding]; other site
393115003470	Switch I region; other site
393115003471	G2 box; other site
393115003472	Switch II region; other site
393115003473	G3 box; other site
393115003474	G4 box; other site
393115003475	G5 box; other site
393115003476	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
393115003477	Helix-turn-helix domains; Region: HTH; cl00088
393115003478	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115003479	dimerization interface [polypeptide binding]; other site
393115003480	Similar to Q8A8A8 Choloylglycine hydrolase from Bacteroides thetaiotaomicron (326 aa). FASTA: opt: 588 Z-score: 716.9 E(): 4.8e-32 Smith-Waterman score: 588; 34.700 identity in 317 aa overlap. Contains an in-frame stop codon at aa 258 ORF ftt1286
393115003481	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
393115003482	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
393115003483	dimer interface [polypeptide binding]; other site
393115003484	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115003485	catalytic residue [active]
393115003486	Similar to Q9KQ90 Hypothetical protein VC2111 from Vibrio cholerae (175 aa). FASTA: opt: 309 Z-score: 410.6 E(): 5.6e-15 Smith-Waterman score: 309; 41.912 identity in 136 aa overlap. ORF ftt1289
393115003487	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
393115003488	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
393115003489	active site
393115003490	HIGH motif; other site
393115003491	KMSKS motif; other site
393115003492	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
393115003493	tRNA binding surface [nucleotide binding]; other site
393115003494	anticodon binding site; other site
393115003495	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
393115003496	dimer interface [polypeptide binding]; other site
393115003497	putative tRNA-binding site [nucleotide binding]; other site
393115003498	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003499	D-galactonate transporter; Region: 2A0114; TIGR00893
393115003500	putative substrate translocation pore; other site
393115003501	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
393115003502	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
393115003503	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
393115003504	Intracellular septation protein A; Region: IspA; cl01098
393115003505	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
393115003506	glucokinase, proteobacterial type; Region: glk; TIGR00749
393115003507	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
393115003508	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115003509	S-adenosylmethionine binding site [chemical binding]; other site
393115003510	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
393115003511	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
393115003512	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
393115003513	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
393115003514	nucleotide binding site/active site [active]
393115003515	HIT family signature motif; other site
393115003516	catalytic residue [active]
393115003517	Similar to Q8A404 Putative amidophosphoribosyl-transferase from Bacteroides thetaiotaomicron (235 aa). FASTA: opt: 247 Z-score: 317.1 E(): 9e-10 Smith-Waterman score: 247; 26.699identity in 206 aa overlap. Contains a frameshift after aa 121 ORF ftt1301c
393115003518	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003519	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
393115003520	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
393115003521	FAD binding domain; Region: FAD_binding_4; pfam01565
393115003522	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
393115003523	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats with a...; Region: EPT_RTPC-like; cl00288
393115003524	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
393115003525	putative active site [active]
393115003526	GTP-binding protein Der; Reviewed; Region: PRK00093
393115003527	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
393115003528	G1 box; other site
393115003529	GTP/Mg2+ binding site [chemical binding]; other site
393115003530	Switch I region; other site
393115003531	G2 box; other site
393115003532	Switch II region; other site
393115003533	G3 box; other site
393115003534	G4 box; other site
393115003535	G5 box; other site
393115003536	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
393115003537	G1 box; other site
393115003538	GTP/Mg2+ binding site [chemical binding]; other site
393115003539	Switch I region; other site
393115003540	G2 box; other site
393115003541	G3 box; other site
393115003542	Switch II region; other site
393115003543	G4 box; other site
393115003544	G5 box; other site
393115003545	ISFtu1, fragment. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. Stop codon at position 136 relative to full length ISftu1
393115003546	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
393115003547	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115003548	Walker A motif; other site
393115003549	ATP binding site [chemical binding]; other site
393115003550	Walker B motif; other site
393115003551	arginine finger; other site
393115003552	Peptidase family M41; Region: Peptidase_M41; pfam01434
393115003553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003554	putative transporter; Provisional; Region: PRK10504
393115003555	putative substrate translocation pore; other site
393115003556	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
393115003557	The excision repair protein UvrA domain I; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion.  Recognition and cleavage of the damaged DNA is a multistep...; Region: ABC_UvrA_I; cd03270
393115003558	The excision repair protein UvrA domain I; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion.  Recognition and cleavage of the damaged DNA is a multistep...; Region: ABC_UvrA_I; cd03270
393115003559	The excision repair protein UvrA domain II; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion.  Recognition and cleavage of the damaged DNA is a multistep...; Region: ABC_UvrA_II; cd03271
393115003560	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
393115003561	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
393115003562	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
393115003563	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
393115003564	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
393115003565	Type II transport protein GspH; Region: GspH; pfam12019
393115003566	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
393115003567	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
393115003568	active site
393115003569	dimer interface [polypeptide binding]; other site
393115003570	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
393115003571	dimer interface [polypeptide binding]; other site
393115003572	active site
393115003573	Thiamine pyrophosphokinase; Region: TPK; cd07995
393115003574	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
393115003575	active site
393115003576	dimerization interface [polypeptide binding]; other site
393115003577	thiamine binding site [chemical binding]; other site
393115003578	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
393115003579	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108
393115003580	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key...; Region: CBS_pair_IMPDH; cd04601
393115003581	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine...; Region: IMPDH; cd00381
393115003582	active site
393115003583	multifunctional aminopeptidase A; Provisional; Region: PRK00913
393115003584	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
393115003585	interface (dimer of trimers) [polypeptide binding]; other site
393115003586	Substrate-binding/catalytic site; other site
393115003587	Zn-binding sites [ion binding]; other site
393115003588	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
393115003589	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
393115003590	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
393115003591	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
393115003592	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
393115003593	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
393115003594	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
393115003595	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
393115003596	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
393115003597	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
393115003598	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
393115003599	Predicted membrane protein [Function unknown]; Region: COG2860
393115003600	UPF0126 domain; Region: UPF0126; pfam03458
393115003601	UPF0126 domain; Region: UPF0126; pfam03458
393115003602	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
393115003603	active site
393115003604	dinuclear metal binding site [ion binding]; other site
393115003605	dimerization interface [polypeptide binding]; other site
393115003606	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
393115003607	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
393115003608	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
393115003609	active site
393115003610	catalytic motif [active]
393115003611	Zn binding site [ion binding]; other site
393115003612	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
393115003613	FAD binding domain; Region: FAD_binding_4; pfam01565
393115003614	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
393115003615	Sulfatase; Region: Sulfatase; cl10460
393115003616	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
393115003617	seryl-tRNA synthetase; Provisional; Region: PRK05431
393115003618	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
393115003619	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme bound...; Region: SerRS_core; cd00770
393115003620	dimer interface [polypeptide binding]; other site
393115003621	active site
393115003622	motif 1; other site
393115003623	motif 2; other site
393115003624	motif 3; other site
393115003625	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
393115003626	FGGY family of carbohydrate kinases, N-terminal domain; Region: FGGY_N; cl09121
393115003627	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
393115003628	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
393115003629	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115003630	Walker A/P-loop; other site
393115003631	ATP binding site [chemical binding]; other site
393115003632	Q-loop/lid; other site
393115003633	ABC transporter signature motif; other site
393115003634	Walker B; other site
393115003635	D-loop; other site
393115003636	H-loop/switch region; other site
393115003637	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
393115003638	ABC transporter transmembrane region; Region: ABC_membrane; cl00549
393115003639	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115003640	Walker A/P-loop; other site
393115003641	ATP binding site [chemical binding]; other site
393115003642	Q-loop/lid; other site
393115003643	ABC transporter signature motif; other site
393115003644	Walker B; other site
393115003645	D-loop; other site
393115003646	H-loop/switch region; other site
393115003647	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
393115003648	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
393115003649	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
393115003650	homotrimer interaction site [polypeptide binding]; other site
393115003651	putative active site [active]
393115003652	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
393115003653	Sulfate transporter family; Region: Sulfate_transp; cl15842
393115003654	Sulfate transporter family; Region: Sulfate_transp; cl15842
393115003655	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
393115003656	Transposase domain (DUF772); Region: DUF772; cl15789
393115003657	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115003658	Transposase domain (DUF772); Region: DUF772; cl15789
393115003659	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
393115003660	active site
393115003661	putative substrate binding region [chemical binding]; other site
393115003662	Neurotransmitter-gated ion-channel ligand binding domain; Region: Neur_chan_LBD; pfam02931
393115003663	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
393115003664	Gentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3435
393115003665	RNA polymerase beta'' subunit; Reviewed; Region: rpoC2; CHL00117
393115003666	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
393115003667	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
393115003668	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; cl01370
393115003669	Intracellular growth locus C protein; Region: IglC; pfam11550
393115003670	Protein of unknown function (DUF877); Region: DUF877; pfam05943
393115003671	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
393115003672	Protein of unknown function (DUF770); Region: DUF770; cl01402
393115003673	Similar to AAP09359 (Q81DH0) Hypothetical protein from Bacillus cereus (393 aa). FASTA: opt: 1167 Z-score: 1358.6 E(): 8e-68 Smith-Waterman score: 1167; 48.413 identity in 378 aa overlap. Contains 2 in-frame stop codons after aa 199 and 336 Identical to FTF1716. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1361c
393115003674	Similar to AAO90848 (Q83BZ2) Major facilitator family transporter from Coxiella burnetii (429 aa). FASTA: opt: 816 Z-score: 918.3 E(): 2.7e-43 Smith-Waterman score: 1063; 41.966 identity in 417 aa overlap. CDS contains a frameshift after aa 49 and is also interrupted by an IS element Identical to FTF1717 upto aa 307. It is part of the duplicated region 1374371..1408281 (again upto aa 307) which is identical to 1767715..1801625 ORF ftt1362
393115003675	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003676	Integrase core domain; Region: rve; cl01316
393115003677	Similar to AAO90849 (Q83BZ1) Trehalase from Coxiella burnetii (543 aa). FASTA: opt: 841 Z-score: 963.6 E(): 8e-46 Smith-Waterman score: 1352; 43.373 identity in 498 aa overlap. Contains 2 in-frame stop codons after aa 71 and 140
393115003678	hypothetical protein; Provisional; Region: PRK08185
393115003679	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
393115003680	intersubunit interface [polypeptide binding]; other site
393115003681	active site
393115003682	zinc binding site [ion binding]; other site
393115003683	Na+ binding site [ion binding]; other site
393115003684	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl09155
393115003685	pyruvate kinase; Provisional; Region: PRK05826
393115003686	domain interfaces; other site
393115003687	active site
393115003688	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
393115003689	Phosphoglycerate kinase; Region: PGK; pfam00162
393115003690	substrate binding site [chemical binding]; other site
393115003691	hinge regions; other site
393115003692	ADP binding site [chemical binding]; other site
393115003693	catalytic site [active]
393115003694	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003695	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
393115003696	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; cl15856
393115003697	transketolase; Reviewed; Region: PRK05899
393115003698	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
393115003699	TPP-binding site [chemical binding]; other site
393115003700	dimer interface [polypeptide binding]; other site
393115003701	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
393115003702	PYR/PP interface [polypeptide binding]; other site
393115003703	dimer interface [polypeptide binding]; other site
393115003704	TPP binding site [chemical binding]; other site
393115003705	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
393115003706	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
393115003707	Ribosomal L32p protein family; Region: Ribosomal_L32p; cl09115
393115003708	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl00390
393115003709	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
393115003710	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
393115003711	dimer interface [polypeptide binding]; other site
393115003712	active site
393115003713	CoA binding pocket [chemical binding]; other site
393115003714	Acyl transferase domain; Region: Acyl_transf_1; cl08282
393115003715	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
393115003716	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
393115003717	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
393115003718	NAD(P) binding site [chemical binding]; other site
393115003719	homotetramer interface [polypeptide binding]; other site
393115003720	homodimer interface [polypeptide binding]; other site
393115003721	active site
393115003722	Phosphopantetheine attachment site; Region: PP-binding; cl09936
393115003723	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
393115003724	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
393115003725	dimer interface [polypeptide binding]; other site
393115003726	active site
393115003727	Similar to Q8F211 Conserved hypothetical protein from Letpospira interrogans (104 aa) opt: 154 Z-score: 241.8 E(): 1.3e-05 Smith-Waterman score: 154; 44.068 identity in 59 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt1378
393115003728	Similar to Q886E0 Oxidoreductase, FAD-binding from Pseudomonas syringae (660 aa) opt: 552 Z-score: 641.8 E(): 6.7e-28 Smith-Waterman score: 552; 38.057 identity in 247 aa overlap. Contains a frameshift after aa 228. Truncation at C-terminal according to FASTA hits ORF ftt1379c
393115003729	Similar to Q89A60 Putative transport protein from Buchnera aphidicola (388 aa). FASTA: opt: 636 Z-score: 709.7 E(): 1.1e-31 636; Smith-Waterman score: 636; 29.793 identity in 386 aa overlap. Contains a frameshift after aa 119 ORF ftt1380
393115003730	Similar to AAP17579 (P33019) Hypothetical protein yeiH from E. coli (349 aa). FASTA: opt: 1005 Z-score: 1126.5 E(): 6.8e-55 Smith-Waterman score: 1005; 49.292 identity in 353 aa overlap. Contains an in-frame stop codon after aa 244 ORF ftt1381
393115003731	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
393115003732	active site
393115003733	dimerization interface [polypeptide binding]; other site
393115003734	16S rRNA methyltransferase B; Provisional; Region: PRK10901
393115003735	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
393115003736	putative RNA binding site [nucleotide binding]; other site
393115003737	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
393115003738	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
393115003739	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003740	Integrase core domain; Region: rve; cl01316
393115003741	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
393115003742	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
393115003743	nucleotide binding pocket [chemical binding]; other site
393115003744	K-X-D-G motif; other site
393115003745	catalytic site [active]
393115003746	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
393115003747	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
393115003748	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
393115003749	Dimer interface [polypeptide binding]; other site
393115003750	BRCT sequence motif; other site
393115003751	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
393115003752	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
393115003753	active site
393115003754	oligomerization interface [polypeptide binding]; other site
393115003755	metal binding site [ion binding]; metal-binding site
393115003756	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115003757	pantoate--beta-alanine ligase; Region: panC; TIGR00018
393115003758	active site
393115003759	nucleotide binding site [chemical binding]; other site
393115003760	HIGH motif; other site
393115003761	KMSKS motif; other site
393115003762	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
393115003763	tetramerization interface [polypeptide binding]; other site
393115003764	active site
393115003765	Type III pantothenate kinase; Region: Pan_kinase; cl09130
393115003766	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
393115003767	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115003768	Family description; Region: UvrD_C_2; cl15862
393115003769	exodeoxyribonuclease V, beta subunit; Region: recB; TIGR00609
393115003770	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
393115003771	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
393115003772	Divergent AAA domain; Region: AAA_4; pfam04326
393115003773	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
393115003774	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
393115003775	putative DNA binding site [nucleotide binding]; other site
393115003776	putative Zn2+ binding site [ion binding]; other site
393115003777	Fusaric acid resistance protein-like; Region: FUSC_2; cl15844
393115003778	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257
393115003779	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
393115003780	Similar to AAO90712 (Q83CC4) Hypothetical protein CBU1203 from Coxiella burnetti (550 aa). FASTA: opt: opt: 1847 Z-score: 2115.4 E(): 5.6e-110 Smith-Waterman score: 1847; 52.075 identity in 530 aa overlap. Contains a frameshift after aa 309 ORF ftt1398c
393115003781	EamA-like transporter family; Region: EamA; cl01037
393115003782	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
393115003783	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
393115003784	non-specific DNA binding site [nucleotide binding]; other site
393115003785	salt bridge; other site
393115003786	sequence-specific DNA binding site [nucleotide binding]; other site
393115003787	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
393115003788	Catalytic site [active]
393115003789	FeoA domain; Region: FeoA; cl00838
393115003790	Sporulation related domain; Region: SPOR; cl10051
393115003791	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
393115003792	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
393115003793	active site
393115003794	Fe-S metabolism associated domain; Region: SufE; cl00951
393115003795	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
393115003796	Similar to Q8GLC1 ORF1 transposase from Acinetobacter baumannii (180 aa) fasta scores; opt: 343 Z-score: 433.4 E(): 2.7e-16 37.500 identity in 160 aa overlap Frameshift after aa's 165 and 252 and stop codon at 263. Mmeber of the IS4 family of insertion sequences. ORF ftt1411
393115003797	prolyl-tRNA synthetase; Provisional; Region: PRK09194
393115003798	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of...; Region: ProRS_core_prok; cd00779
393115003799	dimer interface [polypeptide binding]; other site
393115003800	motif 1; other site
393115003801	active site
393115003802	motif 2; other site
393115003803	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
393115003804	putative deacylase active site [active]
393115003805	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it attaches...; Region: class_II_aaRS-like_core; cl00268
393115003806	active site
393115003807	motif 3; other site
393115003808	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
393115003809	anticodon binding site; other site
393115003810	methionine aminotransferase; Validated; Region: PRK09082
393115003811	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
393115003812	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115003813	homodimer interface [polypeptide binding]; other site
393115003814	catalytic residue [active]
393115003815	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115003816	Predicted amidohydrolase [General function prediction only]; Region: COG0388
393115003817	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
393115003818	putative active site [active]
393115003819	catalytic triad [active]
393115003820	multimer interface [polypeptide binding]; other site
393115003821	dimer interface [polypeptide binding]; other site
393115003822	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
393115003823	putative RNA binding site [nucleotide binding]; other site
393115003824	Flagellin N-methylase; Region: FliB; cl00497
393115003825	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
393115003826	Prolyl 4-hydroxylase alpha subunit homologues; Region: P4Hc; smart00702
393115003827	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; cl15773
393115003828	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115003829	Predicted permeases [General function prediction only]; Region: COG0730; cl00498
393115003830	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
393115003831	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
393115003832	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115003833	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115003834	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
393115003835	active site residue [active]
393115003836	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
393115003837	active site residue [active]
393115003838	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115003839	Integrase core domain; Region: rve; cl01316
393115003840	Predicted acetyltransferase [General function prediction only]; Region: COG3153
393115003841	N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl00357
393115003842	Similar to Q8P215 Hypothetical protein spyM18_0602 from (244 aa). FASTA: opt: 134 Z-score: 160.0 E(): 0.46 Smith-Waterman score: 134; 26.357 identity in 129 aa overlap. Contains a frameshift after aa 85. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1429c
393115003843	Similarity to Q8DCC3 tRNA (guanine-N(7)-)-methyltransferase (239 aa). FASTA: opt: 527 Z-score: 633.6 E(): 1.9e-27 Smith-Waterman score: 527; 54.861 identity in 144 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt1430c
393115003844	LysE type translocator; Region: LysE; cl00565
393115003845	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl01255
393115003846	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
393115003847	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
393115003848	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
393115003849	Ligand binding site; other site
393115003850	Putative Catalytic site; other site
393115003851	DXD motif; other site
393115003852	ABC-2 type transporter; Region: ABC2_membrane; cl11417
393115003853	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
393115003854	The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; Region: ABC_subfamily_A; cd03263
393115003855	Walker A/P-loop; other site
393115003856	ATP binding site [chemical binding]; other site
393115003857	Q-loop/lid; other site
393115003858	ABC transporter signature motif; other site
393115003859	Walker B; other site
393115003860	D-loop; other site
393115003861	H-loop/switch region; other site
393115003862	Transposase domain (DUF772); Region: DUF772; cl15789
393115003863	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115003864	Transposase domain (DUF772); Region: DUF772; cl15789
393115003865	Similar to AAP07946 (Q813X1)Hypothetical Membrane Spanning Protein from Bacillus cereus (255 aa). FASTA: opt: 611 Z-score: 715.3 E(): 5.4e-32 Smith-Waterman score: 611; 40.323identity in 248 aa overlap. Contains a frameshift after aa 131 ORF ftt1437c
393115003866	Similar to P73134 Hypothetical protein from Synechocystis sp. (104 aa). FASTA: 233 Z-score: 308.2 E(): 2.6e-09 Smith-Waterman score: 233; 41.584 identity in 101 aa overlap. Contains a frameshift after aa 18 ORF ftt1438c
393115003867	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
393115003868	active site
393115003869	Similar to Q8XAW5 Putative transport protein from E.coli (475 aa). FASTA: opt: 517 Z-score: 580.9 E(): 1.7e-24 Smith-Waterman score: 517; 27.007 identity in 411 aa overlap . Contains a frameshift after aa 45 ORF ftt1440c
393115003870	Ferritin-like domain; Region: Ferritin; pfam00210
393115003871	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
393115003872	dinuclear metal binding motif [ion binding]; other site
393115003873	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
393115003874	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
393115003875	dimer interface [polypeptide binding]; other site
393115003876	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; cl11613
393115003877	recombination factor protein RarA; Provisional; Region: PRK14700
393115003878	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
393115003879	Ppx/GppA phosphatase family; Region: Ppx-GppA; cl15449
393115003880	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
393115003881	catalytic residues [active]
393115003882	transcription termination factor Rho; Provisional; Region: rho; PRK09376
393115003883	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
393115003884	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
393115003885	RNA binding site [nucleotide binding]; other site
393115003886	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
393115003887	multimer interface [polypeptide binding]; other site
393115003888	Walker A motif; other site
393115003889	ATP binding site [chemical binding]; other site
393115003890	Walker B motif; other site
393115003891	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
393115003892	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
393115003893	active site
393115003894	substrate binding site [chemical binding]; other site
393115003895	metal binding site [ion binding]; metal-binding site
393115003896	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
393115003897	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
393115003898	Substrate binding site; other site
393115003899	Cupin domain; Region: Cupin_2; cl09118
393115003900	ISFtu1, fragment. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. deletion of carboxy terminal region between aa 135 and 238 relative to full length ISftu1.
393115003901	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
393115003902	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
393115003903	NAD binding site [chemical binding]; other site
393115003904	substrate binding site [chemical binding]; other site
393115003905	homodimer interface [polypeptide binding]; other site
393115003906	active site
393115003907	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
393115003908	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
393115003909	substrate binding site; other site
393115003910	tetramer interface; other site
393115003911	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
393115003912	active site
393115003913	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
393115003914	MatE; Region: MatE; cl10513
393115003915	hypothetical protein; Provisional; Region: PRK07579
393115003916	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
393115003917	active site
393115003918	cosubstrate binding site; other site
393115003919	substrate binding site [chemical binding]; other site
393115003920	catalytic site [active]
393115003921	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
393115003922	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
393115003923	inhibitor-cofactor binding pocket; inhibition site
393115003924	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115003925	catalytic residue [active]
393115003926	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
393115003927	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
393115003928	active site
393115003929	dimer interface [polypeptide binding]; other site
393115003930	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
393115003931	Ligand Binding Site [chemical binding]; other site
393115003932	Molecular Tunnel; other site
393115003933	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
393115003934	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115003935	This family is most closely related to the GT1 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis; Region: GT1_WbnK_like; cd03807
393115003936	putative ADP-binding pocket [chemical binding]; other site
393115003937	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
393115003938	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
393115003939	NAD binding site [chemical binding]; other site
393115003940	substrate binding site [chemical binding]; other site
393115003941	homodimer interface [polypeptide binding]; other site
393115003942	active site
393115003943	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
393115003944	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
393115003945	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003946	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115003947	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
393115003948	putative ADP-binding pocket [chemical binding]; other site
393115003949	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003950	NADH(P)-binding; Region: NAD_binding_10; pfam13460
393115003951	NAD(P) binding site [chemical binding]; other site
393115003952	active site
393115003953	Bacterial sugar transferase; Region: Bac_transf; cl00939
393115003954	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
393115003955	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003956	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
393115003957	NAD(P) binding site [chemical binding]; other site
393115003958	homodimer interface [polypeptide binding]; other site
393115003959	substrate binding site [chemical binding]; other site
393115003960	active site
393115003961	Transposase domain (DUF772); Region: DUF772; cl15789
393115003962	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115003963	Transposase domain (DUF772); Region: DUF772; cl15789
393115003964	Similarity to Q82NX6 Putative adenosine deaminase from Streptomyces avermitilis (354 aa). FASTA: opt: 503 Z-score: 606.1 E(): 6.6e-26 Smith-Waterman score: 503; 35.636 identity in 275 aa overlap. Contains a frameshift after aa 45. Truncation a C-terminal according to FASTA hits.
393115003965	L-aspartate oxidase; Provisional; Region: PRK09077
393115003966	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003967	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
393115003968	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
393115003969	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
393115003970	dimerization interface [polypeptide binding]; other site
393115003971	active site
393115003972	Quinolinate synthetase A protein; Region: NadA; cl00420
393115003973	Guanylate kinase; Region: Guanylate_kin; pfam00625
393115003974	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
393115003975	catalytic site [active]
393115003976	G-X2-G-X-G-K; other site
393115003977	helicase 45; Provisional; Region: PTZ00424
393115003978	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
393115003979	ATP binding site [chemical binding]; other site
393115003980	Mg++ binding site [ion binding]; other site
393115003981	motif III; other site
393115003982	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115003983	nucleotide binding region [chemical binding]; other site
393115003984	ATP-binding site [chemical binding]; other site
393115003985	DbpA RNA binding domain; Region: DbpA; pfam03880
393115003986	PPIC-type PPIASE domain; Region: Rotamase; cl08278
393115003987	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
393115003988	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003989	putative substrate translocation pore; other site
393115003990	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003991	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
393115003992	putative substrate translocation pore; other site
393115003993	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003994	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
393115003995	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
393115003996	dimer interface [polypeptide binding]; other site
393115003997	active site
393115003998	galactokinase; Provisional; Region: PRK05322
393115003999	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
393115004000	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
393115004001	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
393115004002	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
393115004003	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
393115004004	Ligand binding site; other site
393115004005	oligomer interface; other site
393115004006	Trm112p-like protein; Region: Trm112p; cl01066
393115004007	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004008	Integrase core domain; Region: rve; cl01316
393115004009	Similar to Q9ZIX7 Putative transposase from Haemophilus gallinarum (216 aa). FASTA: opt: 364 Z-score: 519.1 E(): 4.6e-21 Smith-Waterman score: 364; 67.606 identity in 71 aa overlap. CDS has no start codon due to truncation at the N-terminal ORF ftt1482
393115004010	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
393115004011	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004012	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115004013	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115004014	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
393115004015	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115004016	E3 interaction surface; other site
393115004017	lipoyl attachment site [posttranslational modification]; other site
393115004018	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115004019	E3 interaction surface; other site
393115004020	lipoyl attachment site [posttranslational modification]; other site
393115004021	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115004022	E3 interaction surface; other site
393115004023	lipoyl attachment site [posttranslational modification]; other site
393115004024	e3 binding domain; Region: E3_binding; pfam02817
393115004025	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; cl02008
393115004026	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
393115004027	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
393115004028	dimer interface [polypeptide binding]; other site
393115004029	TPP-binding site [chemical binding]; other site
393115004030	Uncharacterized conserved protein [Function unknown]; Region: COG1565
393115004031	Putative S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_28; pfam02636
393115004032	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
393115004033	dephospho-CoA kinase; Region: TIGR00152
393115004034	CoA-binding site [chemical binding]; other site
393115004035	ATP-binding [chemical binding]; other site
393115004036	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
393115004037	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
393115004038	active site
393115004039	HIGH motif; other site
393115004040	dimer interface [polypeptide binding]; other site
393115004041	KMSKS motif; other site
393115004042	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
393115004043	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
393115004044	Zeta toxin; Region: Zeta_toxin; pfam06414
393115004045	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115004046	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
393115004047	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
393115004048	putative active site [active]
393115004049	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl15772
393115004050	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
393115004051	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
393115004052	MutS domain I; Region: MutS_I; pfam01624
393115004053	MutS family domain IV; Region: MutS_IV; pfam05190
393115004054	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115004055	Walker A/P-loop; other site
393115004056	ATP binding site [chemical binding]; other site
393115004057	Q-loop/lid; other site
393115004058	ABC transporter signature motif; other site
393115004059	Walker B; other site
393115004060	D-loop; other site
393115004061	H-loop/switch region; other site
393115004062	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cl00251
393115004063	SecA binding site; other site
393115004064	Preprotein binding site; other site
393115004065	Similar to Q8CK83 Hypothetical protein from Yersinia pestis (424 aa). FASTA: opt: 297 Z-score: 337.7 bits: 71.5 E(): 5.9e-11 Smith-Waterman score: 298; 24.884 identity in 430 aa overlap. Contains an in-frame stop codon after aa 343 ORF ftt1501
393115004066	Transmembrane amino acid transporter protein; Region: Aa_trans; cl15776
393115004067	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
393115004068	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
393115004069	DNA binding site [nucleotide binding]
393115004070	Int/Topo IB signature motif; other site
393115004071	active site
393115004072	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115004073	S-adenosylmethionine binding site [chemical binding]; other site
393115004074	Domain of unknown function (DUF4124); Region: DUF4124; pfam13511
393115004075	Domain of unknown function (DUF4124); Region: DUF4124; pfam13511
393115004076	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl00076
393115004077	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
393115004078	synthetase active site [active]
393115004079	NTP binding site [chemical binding]; other site
393115004080	metal binding site [ion binding]; metal-binding site
393115004081	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
393115004082	Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in...; Region: PI3Ka; cl00271
393115004083	Transmembrane amino acid transporter protein; Region: Aa_trans; cl15776
393115004084	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
393115004085	EamA-like transporter family; Region: EamA; cl01037
393115004086	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
393115004087	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
393115004088	HSP70 interaction site [polypeptide binding]; other site
393115004089	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
393115004090	substrate binding site [polypeptide binding]; other site
393115004091	dimer interface [polypeptide binding]; other site
393115004092	Similar to Q9HT63 Probable transporter from Pseudomonas aeruginosa (449 aa). FASTA: opt: 476 Z-score: 561.3 E(): 2e-23 Smith-Waterman score: 476; 36.283 identity in 226 aa overlap. Truncated at C-terminal according to FASTA hits ORF ftt1513
393115004093	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
393115004094	Similar to Q92SF1 putative mercuric reductase protein from Rizobium meliloti (473aa). FASTA: opt: 1257 Z-score: 1348.4 E(): 2.9e-67 Smith-Waterman score: 1257; 41.895 identity in 475 aa overlap. Contains an in-frame stop codon after aa 358
393115004095	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115004096	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
393115004097	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
393115004098	DNA binding site [nucleotide binding]
393115004099	active site
393115004100	Similar to Q87RC9 Putative outer membrane lipoprotein Slp from Vibrio parahaemolyticus (185 aa). FASTA: opt: 105 Z-score: 145.9 E(): 2.8 Smith-Waterman score: 105; 26.271identity in 118 aa overlap. Contains an in-frame stop codon after aa 32 and truncation at the C-terminal according to the FASTA matches ORF ftt1519
393115004101	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
393115004102	Similar to Q8A800 diaminopimelate decarboxylase from Bacteroides thetaiotamicron (386 aa). FASTA: opt: 913 Z-score: 1066.5 E(): 1.5e-51 Smith-Waterman score: 1118; 48.000 identity in 375 aa overlap. Contains a frameshift after aa 924
393115004103	L,D-transpeptidase catalytic domain; Region: YkuD; cl15405
393115004104	Transposase domain (DUF772); Region: DUF772; cl15789
393115004105	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115004106	Transposase domain (DUF772); Region: DUF772; cl15789
393115004107	DEAD-like helicases superfamily; Region: DEXDc; smart00487
393115004108	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115004109	ATP binding site [chemical binding]; other site
393115004110	putative Mg++ binding site [ion binding]; other site
393115004111	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115004112	nucleotide binding region [chemical binding]; other site
393115004113	ATP-binding site [chemical binding]; other site
393115004114	Helicase associated domain (HA2); Region: HA2; cl04503
393115004115	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
393115004116	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
393115004117	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
393115004118	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
393115004119	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
393115004120	ArsC family; Region: ArsC; pfam03960
393115004121	catalytic residues [active]
393115004122	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
393115004123	AMP-binding enzyme; Region: AMP-binding; cl15778
393115004124	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
393115004125	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
393115004126	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
393115004127	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
393115004128	active site
393115004129	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
393115004130	Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; Region: ACBP; cl00221
393115004131	acyl-CoA binding pocket [chemical binding]; other site
393115004132	CoA binding site [chemical binding]; other site
393115004133	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
393115004134	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004135	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
393115004136	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
393115004137	substrate binding site [chemical binding]; other site
393115004138	oxyanion hole (OAH) forming residues; other site
393115004139	trimer interface [polypeptide binding]; other site
393115004140	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
393115004141	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
393115004142	dimer interface [polypeptide binding]; other site
393115004143	active site
393115004144	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
393115004145	CoenzymeA binding site [chemical binding]; other site
393115004146	subunit interaction site [polypeptide binding]; other site
393115004147	PHB binding site; other site
393115004148	Similar to Q9ZNS0 Putative sugar transporter from Aribdopsis thaliana (508 aa). FASTA: opt: 409 Z-score: 463.9 E(): 5.5e-18 Smith-Waterman score: 499; 27.171 identity in 449 aa overlap. Contains a frameshift and a possible internal deletion of ~50 aa after aa 199 ORF ftt1533c
393115004149	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
393115004150	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
393115004151	active site
393115004152	Similar to OCD_AGRT5 (P09773) Ornithine cyclodeaminase from Agrobacterium tumefaciens (354 aa). FASTA: opt: 1034 Z-score: 1225.5 E(): 2.1e-60 Smith-Waterman score: 1034; 52.288 identity in 306 aa overlap. Contains a frameshift after aa 142 ORF ftt1535c
393115004153	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
393115004154	Amidinotransferase; Region: Amidinotransf; cl12043
393115004155	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
393115004156	TolB amino-terminal domain; Region: TolB_N; cl00639
393115004157	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
393115004158	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
393115004159	active site
393115004160	phosphorylation site [posttranslational modification]
393115004161	intermolecular recognition site; other site
393115004162	dimerization interface [polypeptide binding]; other site
393115004163	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
393115004164	DNA binding site [nucleotide binding]
393115004165	Similar to Q92R87 Putative sensor histidine kinase transmembrane protein from Rhizobium meliloti (465 aa). FASTA: opt: 509 Z-score: 555.0 E(): 4.6e-23 Smith-Waterman score: 512; 31.023 identity in 303 aa overlap. Contains a frameshift after aa 185 ORF ftt1544
393115004166	Similar to Q9KSY6 Hypothetical protein VC1120 from Vibrio cholerae (426 aa). FASTA: opt: 1106 Z-score: 1280.0 E(): 1.9e-63 Smith-Waterman score: 1106; 41.827 identity in 416 aa overlap. Contains a frameshift after aa 160 ORF ftt1545
393115004167	Similar to Q984A5 Hypothetical protein mll8086 from Rhizobium loti (272 aa). FASTA: opt: 464 Z-score: 572.4 E(): 4.9e-24 Smith-Waterman score: 464; 32.946 identity in 258 aa overlap. Contains 2 frameshifts after aa 54 and 146 ORF ftt1546
393115004168	Similar to Q9A8C7 Cyclopropane-fatty-acyl-phospholipid synthase from Caulobacter crescentus (409 aa). FASTA: opt: 639 Z-score: 746.0 bits: 146.9 E(): 1.1e-33 Smith-Waterman score: 904; 38.653 identity in 401 aa overlap. CDS interrupted by an IS element ORF ftt1547
393115004169	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004170	Integrase core domain; Region: rve; cl01316
393115004171	Protein of unknown function (DUF3833); Region: DUF3833; pfam12915
393115004172	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
393115004173	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004174	NAD(P) binding site [chemical binding]; other site
393115004175	active site
393115004176	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115004177	Fatty acid desaturase; Region: FA_desaturase; pfam00487
393115004178	Di-iron ligands [ion binding]; other site
393115004179	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115004180	ribonuclease R; Region: RNase_R; TIGR02063
393115004181	RNB domain; Region: RNB; pfam00773
393115004182	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase play an important...; Region: S1_RNase_R; cd04471
393115004183	RNA binding site [nucleotide binding]; other site
393115004184	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
393115004185	PseudoU_synth_EcTruB: Pseudouridine synthase, Escherichia coli TruB like. This group consists of bacterial pseudouridine synthases similar to E. coli TruB and Mycobacterium tuberculosis TruB. Pseudouridine synthases catalyze the isomerization of specific...; Region: PseudoU_synth_EcTruB; cd02573
393115004186	RNA binding site [nucleotide binding]; other site
393115004187	active site
393115004188	ribonuclease III; Reviewed; Region: rnc; PRK00102
393115004189	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
393115004190	dimerization interface [polypeptide binding]; other site
393115004191	active site
393115004192	metal binding site [ion binding]; metal-binding site
393115004193	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
393115004194	dsRNA binding site [nucleotide binding]; other site
393115004195	signal peptidase I; Provisional; Region: PRK10861
393115004196	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
393115004197	Catalytic site [active]
393115004198	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
393115004199	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
393115004200	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
393115004201	active site
393115004202	phosphorylation site [posttranslational modification]
393115004203	intermolecular recognition site; other site
393115004204	dimerization interface [polypeptide binding]; other site
393115004205	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
393115004206	DNA binding site [nucleotide binding]
393115004207	Similar to P75762 Hypothetical protein ybhH from E. coli (350 aa). FASTA: opt: opt: 818 Z-score: 956.3 E(): 2.1e-45 Smith-Waterman score: 818; 40.230 identity in 348 aa overlap. Contains a frameshift after aa 112 and an in-frame stop codon after aa 302 ORF ftt1558c
393115004208	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
393115004209	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004210	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
393115004211	active site
393115004212	dimerization interface [polypeptide binding]; other site
393115004213	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
393115004214	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
393115004215	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
393115004216	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
393115004217	substrate binding pocket [chemical binding]; other site
393115004218	chain length determination region; other site
393115004219	substrate-Mg2+ binding site; other site
393115004220	catalytic residues [active]
393115004221	aspartate-rich region 1; other site
393115004222	active site lid residues [active]
393115004223	aspartate-rich region 2; other site
393115004224	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
393115004225	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
393115004226	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115004227	active site
393115004228	Similar to Q8KG78 Glycosyl hydrolase, family 3 from Chlorobium tepidum (372 aa). FASTA: opt: 811 Z-score: 919.2 E(): 2.4e-43 Smith-Waterman score: 811; 40.822 identity in 365 aa overlap. Contains a frameshift after aa 28 ORF ftt1565c
393115004229	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
393115004230	metal binding site [ion binding]; metal-binding site
393115004231	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
393115004232	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
393115004233	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
393115004234	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
393115004235	active site
393115004236	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
393115004237	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
393115004238	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
393115004239	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
393115004240	trimer interface [polypeptide binding]; other site
393115004241	active site
393115004242	UDP-GlcNAc binding site [chemical binding]; other site
393115004243	lipid binding site [chemical binding]; lipid-binding site
393115004244	periplasmic chaperone; Provisional; Region: PRK10780
393115004245	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
393115004246	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
393115004247	Surface antigen variable number repeat; Region: Surf_Ag_VNR; cl10520
393115004248	Surface antigen variable number repeat; Region: Surf_Ag_VNR; cl10520
393115004249	Surface antigen variable number repeat; Region: Surf_Ag_VNR; cl10520
393115004250	Surface antigen variable number repeat; Region: Surf_Ag_VNR; cl10520
393115004251	Surface antigen; Region: Bac_surface_Ag; cl03097
393115004252	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
393115004253	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
393115004254	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
393115004255	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
393115004256	DNA gyrase subunit A; Validated; Region: PRK05560
393115004257	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA...; Region: TOP4c; cd00187
393115004258	CAP-like domain; other site
393115004259	active site
393115004260	primary dimer interface [polypeptide binding]; other site
393115004261	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004262	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004263	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004264	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004265	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004266	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004267	N-acetylglucosamine-binding protein A; Reviewed; Region: PRK13211
393115004268	Chitin/cellulose binding domain. Putative carbohydrate binding domain found in many different glycosyl hydrolase enzymes. May occur in tandem arrangements; Region: ChtBD3; cl00046
393115004269	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
393115004270	ligand binding site [chemical binding]; other site
393115004271	active site
393115004272	UGI interface [polypeptide binding]; other site
393115004273	catalytic site [active]
393115004274	Restriction endonuclease [Defense mechanisms]; Region: COG3587
393115004275	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115004276	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
393115004277	GIY-YIG motif/motif A; other site
393115004278	putative active site [active]
393115004279	putative metal binding site [ion binding]; other site
393115004280	Similar to Q9XBI6 Type III restriction-modification system enzyme Mod from Bacillus cereus (669 aa). FASTA: opt: 825 Z-score: 875.5 E(): 6.5e-41 Smith-Waterman score: 856; 35.728identity in 515 aa overlap. Contains frameshifts after aa 175 and 387. Truncation at C-terminal according to FASTA hits ORF ftt1582c
393115004281	Similar to Q9JTA5 Insertion element IS1016 transposase from serogroup A Neisseria meningitidis Z2491 (151 aa). FASTA: opt: 610 Z-score: 830.4 E(): 2.1e-38 Smith-Waterman score: 610; 74.194 identity (74.1940ngapped) in 124 aa overlap N-terminal sequence is similar to FTF1121 ORF ftt1583
393115004282	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004283	Integrase core domain; Region: rve; cl01316
393115004284	Domain of unknown function (DUF4282); Region: DUF4282; pfam14110
393115004285	Similar to Q8XT33 Probable amino-acid permease transmembrane protein from Ralstonia solanacearum (543 aa). FASTA: opt: 908 Z-score: 1045.4 E(): 2.2e-50 Smith-Waterman score: 910; 32.230identity in 453 aa overlap ORF ftt1587c
393115004286	Similar to ABC-type transporter Q8D5S9 from Vibrio vulnificus (242 aa). FASTA: opt: 99 Z-score: 146.3 E(): 2.7 Smith-Waterman score: 99; 30.337 identity in 89 aa overlap ORF ftt1588c
393115004287	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
393115004288	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004289	VacJ like lipoprotein; Region: VacJ; cl01073
393115004290	Similar to Q9ZNL0 Chitinase A from Clostridium paraputrificum (832 aa). FASTA: opt: 196 Z-score: 216.1 E(): 0.00035 Smith-Waterman score: 203; 22.770identity in 426 aa overlap ORF ftt1592c
393115004291	Similar to Q8Y4H4 Hypothetical protein lmo2467 from Listeria monocytogenes (478 aa) opt: 362 Z-score: 427.2 E(): 6.1e-16 Smith-Waterman score: 362; 46.226 identity in 106 aa overlap ORF ftt1593c
393115004292	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115004293	Helix-turn-helix domains; Region: HTH; cl00088
393115004294	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115004295	dimerization interface [polypeptide binding]; other site
393115004296	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004297	Integrase core domain; Region: rve; cl01316
393115004298	Fumarate hydratase (Fumerase); Region: Fumerase; cl00851
393115004299	Fumarase C-terminus; Region: Fumerase_C; cl00795
393115004300	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
393115004301	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
393115004302	ssDNA binding site; other site
393115004303	generic binding surface II; other site
393115004304	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115004305	ATP binding site [chemical binding]; other site
393115004306	putative Mg++ binding site [ion binding]; other site
393115004307	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115004308	nucleotide binding region [chemical binding]; other site
393115004309	ATP-binding site [chemical binding]; other site
393115004310	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361
393115004311	Ribosomal L28 family; Region: Ribosomal_L28; cl00367
393115004312	Ribosomal protein L33; Region: Ribosomal_L33; cl00383
393115004313	septum formation inhibitor; Reviewed; Region: minC; PRK04804
393115004314	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
393115004315	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
393115004316	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
393115004317	Switch I; other site
393115004318	Switch II; other site
393115004319	Septum formation topological specificity factor MinE; Region: MinE; cl00538
393115004320	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
393115004321	ABC (ATP-binding cassette) transport system involved in resistant to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex...; Region: ABC_Org_Solvent_Resistant; cd03261
393115004322	Walker A/P-loop; other site
393115004323	ATP binding site [chemical binding]; other site
393115004324	Q-loop/lid; other site
393115004325	ABC transporter signature motif; other site
393115004326	Walker B; other site
393115004327	D-loop; other site
393115004328	H-loop/switch region; other site
393115004329	Permease; Region: Permease; cl00510
393115004330	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
393115004331	mce related protein; Region: MCE; pfam02470
393115004332	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; cl01074
393115004333	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
393115004334	anti sigma factor interaction site; other site
393115004335	regulatory phosphorylation site [posttranslational modification]; other site
393115004336	BolA-like protein; Region: BolA; cl00386
393115004337	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004338	Integrase core domain; Region: rve; cl01316
393115004339	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
393115004340	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
393115004341	active site
393115004342	HIGH motif; other site
393115004343	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
393115004344	KMSKS motif; other site
393115004345	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
393115004346	tRNA binding surface [nucleotide binding]; other site
393115004347	anticodon binding site; other site
393115004348	HemK family putative methylases; Region: hemK_fam; TIGR00536
393115004349	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115004350	S-adenosylmethionine binding site [chemical binding]; other site
393115004351	Similar to AAO91456 Drug resistance transporter,Bcr/Cfl family from Coxiella burnetii (409 aa). FASTA: opt: 427 Z-score: 505.5 E(): 2.6e-20 Smith-Waterman score: 442; 29.966 identity in 297 aa overlap. Contains an in-frame stop codon after aa 57. Truncation at the C-terminal according to FASTA hits ORF ftt1618
393115004352	Similar to AAP09454 (Q81D84) Aminoglycoside N6'-acetyltransferase from Bacillus cereus (169 aa). FASTA: opt: 317 Z-score: 407.6 E(): 7.5e-15 Smith-Waterman score: 317; 36.879 identity in 141 aa overlap. Contains an in-frame stop codon after aa 28 ORF ftt1619
393115004353	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004354	Integrase core domain; Region: rve; cl01316
393115004355	Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilW; COG4966
393115004356	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
393115004357	Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilW; COG4966
393115004358	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
393115004359	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
393115004360	Domain of unknown function DUF21; Region: DUF21; pfam01595
393115004361	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
393115004362	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
393115004363	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
393115004364	DXD motif; other site
393115004365	Sodium:solute symporter family; Region: SSF; cl00456
393115004366	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
393115004367	putative active site [active]
393115004368	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
393115004369	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
393115004370	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
393115004371	active site
393115004372	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
393115004373	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115004374	Ftsk gamma domain; Region: Ftsk_gamma; cl09645
393115004375	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
393115004376	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl01065
393115004377	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
393115004378	Cation transport protein; Region: TrkH; cl10514
393115004379	Similar to PROQ_HAEIN P44286 ProP effector homolog from Haemphilus influenzae (209 aa). FASTA: opt: 201 Z-score: 237.4 bits: 51.8 E(): 2.3e-05 Smith-Waterman score: 201; 28.365identity in 208 aa overlap. CDS has an extended N-terminal sequence and a truncated C-terminal sequence according to FASTA hits ORF ftt1640c
393115004380	Similar to Q8RN28 HsdR from Campylobacter jejuni (1031 aa). FASTA: 647 Z-score: 728.9 E(): 9.4e-33 Smith-Waterman score: 649; 57.222 identity in 180 aa overlap. No start codon due to truncation at N-terminal according to FASTA hits. FTF1641c also has a partial match to Q8RN31 (110-360 aa). Potential deletion between FTF1641c and FTF1642c
393115004381	Similar to Q8RN31 HsdR from Campylobacter jejuni (1031 aa). FASTA: opt: 972 Z-score: 1176.4 E(): 1.1e-57 Smith-Waterman score: 972; 66.063identity in 221 aa overlap. This CDS lacks a start codon due to an interruption of an ISFtu1 element at the N-terminal end. It is also truncated at the C-terminal according to FASTA hits. FTF1642c also has a partial match to Q8RN31 (900 to end aa). Potential deletion between FTF1641c and FTF1642c
393115004382	ISFtu1, pseudogene. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. Additional frameshift at aa 131
393115004383	Glycosyl hydrolases family 32 N-terminal domain; Region: Glyco_hydro_32N; pfam00251
393115004384	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
393115004385	substrate binding [chemical binding]; other site
393115004386	active site
393115004387	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
393115004388	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115004389	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004390	putative substrate translocation pore; other site
393115004391	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cl00253
393115004392	putative active site [active]
393115004393	dimerization interface [polypeptide binding]; other site
393115004394	putative tRNAtyr binding site [nucleotide binding]; other site
393115004395	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108
393115004396	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl09108
393115004397	phosphate binding site [ion binding]; other site
393115004398	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase contains two...; Region: OMP_decarboxylase_like; cd04725
393115004399	active site
393115004400	dimer interface [polypeptide binding]; other site
393115004401	Similar to Q87VL0 Transglutaminase-like superfamily domain protein from Pseudomonas syringae (1092 aa). FASTA: opt: 4030 Z-score: 4586.9 bits: 860.5 E(): 0 Smith-Waterman score: 4030; 53.724 identity in 1074 aa overlap. Contains a stop codon after aa 769 ORF ftt1649
393115004402	Chorismate mutase type II; Region: CM_2; cl00693
393115004403	SOUL heme-binding protein; Region: SOUL; pfam04832
393115004404	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115004405	Helix-turn-helix domains; Region: HTH; cl00088
393115004406	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115004407	dimerization interface [polypeptide binding]; other site
393115004408	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004409	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
393115004410	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115004411	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
393115004412	Protein of unknown function (DUF1415); Region: DUF1415; cl01301
393115004413	Domain of unknown function (DUF4325); Region: DUF4325; pfam14213
393115004414	dihydroorotase; Reviewed; Region: PRK09236
393115004415	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
393115004416	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
393115004417	active site
393115004418	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
393115004419	Similar to Q9APF7 Major acid phosphatase from Legionella pneumophila (395 aa). FASTA: opt 803 Z-score: 934.8 E(): 3.2e-44 Smith-Waterman score: 803; 39.359 identity in 343 aa overlap. Contains an in-frame stop codon after aa 159. ORF ftt1662c
393115004420	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
393115004421	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; cl03056
393115004422	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
393115004423	catalytic site [active]
393115004424	subunit interface [polypeptide binding]; other site
393115004425	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
393115004426	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115004427	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115004428	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
393115004429	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115004430	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115004431	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
393115004432	IMP binding site; other site
393115004433	dimer interface [polypeptide binding]; other site
393115004434	interdomain contacts; other site
393115004435	partial ornithine binding site; other site
393115004436	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
393115004437	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
393115004438	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004439	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
393115004440	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004441	Stress responsive A/B Barrel Domain; Region: Dabb; cl15807
393115004442	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
393115004443	Transmembrane amino acid transporter protein; Region: Aa_trans; cl15776
393115004444	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004445	Integrase core domain; Region: rve; cl01316
393115004446	Similar to Q88AM3 Na+/H+ antiporter NhaP from Pseudomonas putida (419 aa). FASTA: opt: 400 z-score: 489.1 E(): 2.2e-19 Smith-Waterman score: 411; 36.458 identity in 192 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring causing a truncation at the C-terminal end.
393115004447	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
393115004448	catalytic motif [active]
393115004449	Zn binding site [ion binding]; other site
393115004450	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cl00161
393115004451	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
393115004452	Lumazine binding domain; Region: Lum_binding; pfam00677
393115004453	Lumazine binding domain; Region: Lum_binding; pfam00677
393115004454	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
393115004455	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; cl00336
393115004456	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
393115004457	dimerization interface [polypeptide binding]; other site
393115004458	active site
393115004459	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
393115004460	homopentamer interface [polypeptide binding]; other site
393115004461	active site
393115004462	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
393115004463	active site
393115004464	catalytic residues [active]
393115004465	metal binding site [ion binding]; metal-binding site
393115004466	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
393115004467	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
393115004468	GTP-binding protein LepA; Provisional; Region: PRK05433
393115004469	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
393115004470	G1 box; other site
393115004471	putative GEF interaction site [polypeptide binding]; other site
393115004472	GTP/Mg2+ binding site [chemical binding]; other site
393115004473	Switch I region; other site
393115004474	G2 box; other site
393115004475	G3 box; other site
393115004476	Switch II region; other site
393115004477	G4 box; other site
393115004478	G5 box; other site
393115004479	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
393115004480	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
393115004481	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
393115004482	Ribosomal protein S20; Region: Ribosomal_S20p; cl00384
393115004483	SmpA / OmlA family; Region: SmpA_OmlA; cl01095
393115004484	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
393115004485	dimer interface [polypeptide binding]; other site
393115004486	active site
393115004487	Similar to AAP08939 (Q81EK2) Hypothetical protein from Bacillus cereus (755 aa). FASTA: opt: 1438 Z-score: 1569.7 E(): 1.4e-79 Smith-Waterman score: 1459; 32.429 identity in 737 aa overlap. Contains a frameshift after aa 234 and an in-frame stop codon after aa 314 ORF ftt1682
393115004488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004489	putative substrate translocation pore; other site
393115004490	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
393115004491	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115004492	Helix-turn-helix domains; Region: HTH; cl00088
393115004493	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115004494	putative effector binding pocket; other site
393115004495	dimerization interface [polypeptide binding]; other site
393115004496	Fusaric acid resistance protein-like; Region: FUSC_2; cl15844
393115004497	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
393115004498	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115004499	catalytic residue [active]
393115004500	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl15754
393115004501	Transmembrane amino acid transporter protein; Region: Aa_trans; cl15776
393115004502	aromatic amino acid transport protein; Region: araaP; TIGR00837
393115004503	Protein of unknown function (DUF1275); Region: DUF1275; cl01453
393115004504	Nitroreductase family. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source...; Region: Nitroreductase; cd02136
393115004505	putative FMN binding site [chemical binding]; other site
393115004506	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004507	Integrase core domain; Region: rve; cl01316
393115004508	Protein of unknown function (DUF328); Region: DUF328; cl01143
393115004509	Predicted membrane protein [Function unknown]; Region: COG4125
393115004510	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
393115004511	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
393115004512	oligomerisation interface [polypeptide binding]; other site
393115004513	mobile loop; other site
393115004514	roof hairpin; other site
393115004515	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
393115004516	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
393115004517	ring oligomerisation interface [polypeptide binding]; other site
393115004518	ATP/Mg binding site [chemical binding]; other site
393115004519	stacking interactions; other site
393115004520	hinge regions; other site
393115004521	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004522	Integrase core domain; Region: rve; cl01316
393115004523	formate dehydrogenase; Provisional; Region: PRK07574
393115004524	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004525	RNA polymerase beta'' subunit; Reviewed; Region: rpoC2; CHL00117
393115004526	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
393115004527	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
393115004528	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; cl01370
393115004529	Intracellular growth locus C protein; Region: IglC; pfam11550
393115004530	Protein of unknown function (DUF877); Region: DUF877; pfam05943
393115004531	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
393115004532	Protein of unknown function (DUF770); Region: DUF770; cl01402
393115004533	Similar to AAP09359 (Q81DH0) Hypothetical protein from Bacillus cereus (393 aa). FASTA: opt: 1167 Z-score: 1358.6 E(): 8e-68 Smith-Waterman score: 1167; 48.413 identity in 378 aa overlap. Contains 2 in-frame stop codons after aa 199 and 336. Identical to FTF1361. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1716c
393115004534	Similar to AAO90848 (Q83BZ2) Major facilitator family transporter from Coxiella burnetii (429 aa). FASTA: opt: 688 Z-score: 817.3 E(): 1.1e-37 Smith-Waterman score: 688; 40.149 identity in 269 aa overlap. CDS contains a frameshift after aa 49 and is also interrupted by an ISftu1 element. It is truncated at C-terminal due to insertion of an ISFtu1 element Identical to FTF1362 upto aa 307. It is part of the duplicated region 1767715..1801625 (again upto aa 307) which is identical to 1374371..1408281 ORF ftt1717
393115004535	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004536	Integrase core domain; Region: rve; cl01316
393115004537	Similar to MTF1_FUSNU (P34906) Modification methylase FnuDI from Fusobacterium nucleatum (344 aa). FASTA: opt: 740 Z-score: 941.7 E(): 3e-44 Smith-Waterman score: 740; 67.702 identity in 161 aa overlap. Numerous frameshifts and truncation of gene at C-terminus according to FASTA hits ORF ftt1719c
393115004538	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
393115004539	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
393115004540	dimerization interface [polypeptide binding]; other site
393115004541	ATP binding site [chemical binding]; other site
393115004542	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
393115004543	dimerization interface [polypeptide binding]; other site
393115004544	ATP binding site [chemical binding]; other site
393115004545	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
393115004546	putative active site [active]
393115004547	catalytic triad [active]
393115004548	amidophosphoribosyltransferase; Provisional; Region: PRK09246
393115004549	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
393115004550	active site
393115004551	tetramer interface [polypeptide binding]; other site
393115004552	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115004553	active site
393115004554	Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076
393115004555	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
393115004556	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115004557	catalytic residue [active]
393115004558	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
393115004559	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
393115004560	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004561	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
393115004562	putative protease; Provisional; Region: PRK15452
393115004563	Peptidase family U32; Region: Peptidase_U32; cl03113
393115004564	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
393115004565	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004566	putative substrate translocation pore; other site
393115004567	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl15357
393115004568	transmembrane helices; other site
393115004569	Similar to Q8Y280 Probable ATP-binding transport ABC transporter protein from Ralstonia solancearum (614 aa). FASTA: opt: 752 Z-score: 802.5 E(): 8.3e-37 Smith-Waterman score: 752; 29.020 identity in 510 aa overlap. Contains a frameshift after aa 322 and an in-frame stop codon after aa 140
393115004570	Amino acid permease; Region: AA_permease_2; pfam13520
393115004571	Obg family GTPase CgtA; Region: Obg_CgtA; TIGR02729
393115004572	GTP1/OBG; Region: GTP1_OBG; pfam01018
393115004573	Obg GTPase; Region: Obg; cd01898
393115004574	G1 box; other site
393115004575	GTP/Mg2+ binding site [chemical binding]; other site
393115004576	Switch I region; other site
393115004577	G2 box; other site
393115004578	G3 box; other site
393115004579	Switch II region; other site
393115004580	G4 box; other site
393115004581	G5 box; other site
393115004582	Transmembrane amino acid transporter protein; Region: Aa_trans; cl15776
393115004583	aromatic amino acid transport protein; Region: araaP; TIGR00837
393115004584	Similar to Q47938 Outer membrane protein from Francisella tularensis (336 aa). FASTA: opt: 516 Z-score: 592.2 E(): 3.9e-25 Smith-Waterman score: 516; 41.589 identity in 214 aa overlap. Contains an in-frame stop codon after aa 71 and truncation at C-terminal according to FASTA hits No transmembrane helix predicted.
393115004585	Similar to Q8EKN3 Transcriptional regulatory protein KdpE (229 aa) FASTA: initn: 561 init1: 517 opt: 604 Z-score: 717.3 bits: 139.9 E(): 4.6e-32 Smith-Waterman score: 604; 41.704 identity (42.66139ngapped) in 223 aa overlap. (Part of two-component regulatory system). Contains a frameshift after aa 14 and an in-frame stop codon after aa 110. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115004586	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
393115004587	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
393115004588	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
393115004589	Ligand Binding Site [chemical binding]; other site
393115004590	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
393115004591	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
393115004592	dimer interface [polypeptide binding]; other site
393115004593	phosphorylation site [posttranslational modification]
393115004594	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115004595	ATP binding site [chemical binding]; other site
393115004596	Mg2+ binding site [ion binding]; other site
393115004597	G-X-G motif; other site
393115004598	K+-transporting ATPase, c chain; Region: KdpC; cl00944
393115004599	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
393115004600	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
393115004601	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115004602	Similar to Q98GX5 Potassium-transporting ATPase, A chain, from (567 aa) FASTA: opt: 1342 Z-score: 1546.7 E(): 2.6e-78 Smith-Waterman score: 1401; 42.707 identity in 569 aa overlap. Contains numerous in-frame stop codons and a frameshift after aa 112
393115004603	No start codon ORF ftt1740c
393115004604	Similar to Q9F7P9 Predicted NAD-dependent formate dehydrenase from Gamma-proteobacterium EBAC31A08 (398 aa). FASTA: opt: 740 Z-score: 987.4 E(): 4.2e-47 Smith-Waterman score: 740; 72.464 identity in 138 aa overlap. This CDS has no start codon due to truncation at N-terminal by the insertion of an ISFtu1 element ORF ftt1741c
393115004605	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004606	Integrase core domain; Region: rve; cl01316
393115004607	Similar to AAO91087 (Q9CNR2) Monovalent cation/proton antiporter from Bos indicus (417 aa). FASTA:opt: 323 Z-score: 405.5 E(): 9.8e-15 Smith-Waterman score: 323; 36.424 identity in 151 aa overlap. This CDS lacks a start codon due to an interruption of an ISFtu1 element at the N-terminal end and is truncated at the C-terminal according to FASTA hits ORF ftt1743
393115004608	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
393115004609	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
393115004610	dimer interface [polypeptide binding]; other site
393115004611	PYR/PP interface [polypeptide binding]; other site
393115004612	TPP binding site [chemical binding]; other site
393115004613	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; cl00815
393115004614	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
393115004615	TPP-binding site [chemical binding]; other site
393115004616	dimer interface [polypeptide binding]; other site
393115004617	Similar to P73195 Hypothetical protein sll1584 from Synechocystis sp (strain PCC 6803)(134 aa). FASTA: opt: 238 Z-score: 356.0 E(): 6.1e-12 Smith-Waterman score: 238; 51.471identity in 68 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt1745c
393115004618	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
393115004619	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
393115004620	tandem repeat interface [polypeptide binding]; other site
393115004621	oligomer interface [polypeptide binding]; other site
393115004622	active site residues [active]
393115004623	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
393115004624	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
393115004625	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cl00251
393115004626	SecA binding site; other site
393115004627	Preprotein binding site; other site
393115004628	recombinase A; Provisional; Region: recA; PRK09354
393115004629	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
393115004630	hexamer interface [polypeptide binding]; other site
393115004631	Walker A motif; other site
393115004632	ATP binding site [chemical binding]; other site
393115004633	Walker B motif; other site
393115004634	RecX family; Region: RecX; cl00936
393115004635	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
393115004636	dimer interface [polypeptide binding]; other site
393115004637	ssDNA binding site [nucleotide binding]; other site
393115004638	tetramer (dimer of dimers) interface [polypeptide binding]; other site
393115004639	propionate/acetate kinase; Provisional; Region: PRK12379
393115004640	Acetokinase family; Region: Acetate_kinase; cl01029
393115004641	phosphate acetyltransferase; Reviewed; Region: PRK05632
393115004642	DRTGG domain; Region: DRTGG; cl12147
393115004643	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl00390
393115004644	Similar to Q9SEK4 Succinic semialdehyde dehydrogenase from Arabidopsis thaliana (528 aa). FASTA: opt: 938 bits: 211.9 E(): 3e-53 Smith-Waterman score: 938; 53.381 identity in a 281 aa overlap. Contains a frameshift after aa 225. This CDS is also disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end.
393115004645	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004646	Integrase core domain; Region: rve; cl01316
393115004647	Similar to AAO91543 (Q83A52) Major facilitator family transporter from Coxiella burnetii (443 aa). FASTA: opt: 1009 Z-score: 1114.6 E(): 3.1e-54 Smith-Waterman score: 1009; 40.394 identity in 406 aa overlap. Contains a frameshift after aa 72 and an in-frame stop codon after aa 181. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1757c
393115004648	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
393115004649	Similar to P95483 Oxidase-related protein from Thermotoga maritima (321 aa). FASTA: opt: 358 Z-score: 431.0 E(): 3.7e-16 Smith-Waterman score: 527; 31.731 identity in 312 aa overlap. Contains a frameshift after aa 130 ORF ftt1759c
393115004650	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
393115004651	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
393115004652	putative catalytic site [active]
393115004653	putative metal binding site [ion binding]; other site
393115004654	putative phosphate binding site [ion binding]; other site
393115004655	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
393115004656	putative acyl-acceptor binding pocket; other site
393115004657	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
393115004658	putative acyl-acceptor binding pocket; other site
393115004659	Ferredoxin [Energy production and conversion]; Region: COG1146
393115004660	4Fe-4S binding domain; Region: Fer4; cl02805
393115004661	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
393115004662	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004663	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
393115004664	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115004665	ATP-grasp domain; Region: ATP-grasp_4; cl03087
393115004666	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
393115004667	active site
393115004668	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
393115004669	Clp amino terminal domain; Region: Clp_N; pfam02861
393115004670	Clp amino terminal domain; Region: Clp_N; pfam02861
393115004671	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115004672	Walker A motif; other site
393115004673	ATP binding site [chemical binding]; other site
393115004674	Walker B motif; other site
393115004675	arginine finger; other site
393115004676	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115004677	Walker A motif; other site
393115004678	ATP binding site [chemical binding]; other site
393115004679	Walker B motif; other site
393115004680	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
393115004681	Similar to Q9CK00 Hypothetical protein PM1838 from Pasteurella multocida (234 aa). FASTA: opt: 390 Z-score: 473.8 E(): 1.5e-18 Smith-Waterman score: 390; 29.583 identity in 240 aa overlap. Contains an in-frame stop codon after aa 114 ORF ftt1770
393115004682	tryptophan synthase subunit alpha; Provisional; Region: trpA; PRK13111
393115004683	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
393115004684	substrate binding site [chemical binding]; other site
393115004685	active site
393115004686	catalytic residues [active]
393115004687	heterodimer interface [polypeptide binding]; other site
393115004688	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
393115004689	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115004690	catalytic residue [active]
393115004691	Similar to Q8RH52 Thermostable carboxypeptidase 1 (496 aa) FASTA: opt: 1208 Z-score: 1432.3 E(): 6.9e-72 Smith-Waterman score: 1208; 51.734 identity in 346 aa overlap. Truncated at N-terminal and has no start codon. ORF ftt1774c
393115004692	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
393115004693	Voltage gated chloride channel; Region: Voltage_CLC; pfam00654
393115004694	Cl- selectivity filter; other site
393115004695	Cl- binding residues [ion binding]; other site
393115004696	pore gating glutamate residue; other site
393115004697	dimer interface [polypeptide binding]; other site
393115004698	H+/Cl- coupling transport residue; other site
393115004699	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
393115004700	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004701	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004702	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004703	Similar to AAO91223 (Q83AZ7) Membrane protein,putative, from Coxiella burnetii (205 aa). FASTA: opt: 303 Z-score: 367.4 E(): 1.3e-12 Smith-Waterman score: 303; 29.299identity in 157 aa overlap. Contains a frameshift after aa 149. This CDS is disrupted by the insertion of an ISFtu1 element occurring near the C-terminal end. ORF ftt1779
393115004704	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
393115004705	Integrase core domain; Region: rve; cl01316
393115004706	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115004707	S-adenosylmethionine binding site [chemical binding]; other site
393115004708	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
393115004709	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
393115004710	Walker A/P-loop; other site
393115004711	ATP binding site [chemical binding]; other site
393115004712	Q-loop/lid; other site
393115004713	ABC transporter signature motif; other site
393115004714	Walker B; other site
393115004715	D-loop; other site
393115004716	H-loop/switch region; other site
393115004717	ABC transporter; Region: ABC_tran_2; pfam12848
393115004718	ABCF_EF-3  Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth.  EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated...; Region: ABCF_EF-3; cd03221
393115004719	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004720	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115004721	putative substrate translocation pore; other site
393115004722	Similar to O86705 Hypothetical protein SCO6523 from Streptomyces coelicolour (346 aa). FASTA: opt: 659 Z-score: 775.4 E(): 2.5e-35 Smith-Waterman score: 659; 37.262 identity in 263 aa overlap. Contains a frameshift after aa 165. Truncation at N-terminus according to FASTA hits ORF ftt1786
393115004723	LysE type translocator; Region: LysE; cl00565
393115004724	Similar to ICIA_VIBCH (Q9KUN3) Chromosome initiation inhibitor from Vibrio choleraea (298 aa). FASTA: opt: 628 Z-score: 730.4 E(): 7.8e-33 Smith-Waterman score: 628; 38.000identity in 300 aa overlap. Contains a frameshift after aa 83. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115004725	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115004726	Similar to Q8H0S9 Putative aminopeptidase from Aribdopsis thaliana (883 aa). FASTA: opt: 185 Z-score: 275.4 E(): 1.9e-07 Smith-Waterman score: 185; 53.571 identity in 56 aa overlap. Contains an in-frame stop codon after aa 61. Truncation at both N- and C-terminals according to FAST hits ORF ftt1790c
393115004727	Similar to Q9ZIX7, putative transposase from Haemophilus gallinarum (216 aa). FASTA: opt: 566 Z-score: 710.4 E(): 1e-31 Smith-Waterman score: 566; 42.056 identity in 214 aa overlap. Stop codon at aa position 99 Identical to FTF1053c. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. ORF ftt1792c
393115004728	aminopeptidase N; Provisional; Region: pepN; PRK14015
393115004729	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
393115004730	active site
393115004731	Zn binding site [ion binding]; other site
393115004732	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
393115004733	putative dimer interface [polypeptide binding]; other site
393115004734	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
393115004735	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
393115004736	active site
393115004737	ribulose/triose binding site [chemical binding]; other site
393115004738	phosphate binding site [ion binding]; other site
393115004739	substrate (anthranilate) binding pocket [chemical binding]; other site
393115004740	product (indole) binding pocket [chemical binding]; other site
393115004741	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric; Region: PRAI; cd00405
393115004742	active site
393115004743	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
393115004744	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
393115004745	NHLP leader peptide domain; Region: TOMM_pelo; cl15464
393115004746	Similar to Q8YVF1 Hypothetical protein All2027 from Anabaena sp. (111 aa). FASTA: opt: 132 Z-score: 181.3 E(): 0.03 Smith-Waterman score: 132; 31.034 identity in 87 aa overlap. Contains an in-frame stop codon after aa 48 ORF ftt1799c
393115004747	Similar to Q8FHV8 Anthranilate synthase component II from E. coli (531 aa). FASTA: opt: 1761 Z-score: 1951.1 E(): 8e-101 Smith-Waterman score: 1761; 49.808 identity in 522 aa overlap. Contains frameshift after aa 192 unknown EC_number 4.3.1.27
393115004748	anthranilate synthase component I; Provisional; Region: PRK13564
393115004749	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
393115004750	chorismate binding enzyme; Region: Chorismate_bind; cl10555
393115004751	Helix-turn-helix domains; Region: HTH; cl00088
393115004752	ribonuclease G; Provisional; Region: PRK11712
393115004753	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
393115004754	homodimer interface [polypeptide binding]; other site
393115004755	oligonucleotide binding site [chemical binding]; other site