-- dump date 20120504_145557 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002474655.1 219870280 7278596 2..1021 1 NC_011852.1 COG:G;COG0057; glyceraldehyde-3-phosphate dehydrogenase 1021 gapA 7278596 gapA Haemophilus parasuis SH0165 glyceraldehyde-3-phosphate dehydrogenase YP_002474655.1 2 D 557723 CDS YP_002474656.1 219870281 7278617 1967..4633 1 NC_011852.1 COG:L;COG0188; DNA gyrase subunit A 4633 gyrA 7278617 gyrA Haemophilus parasuis SH0165 DNA gyrase subunit A YP_002474656.1 1967 D 557723 CDS YP_002474657.1 219870282 7278619 complement(8972..9094) 1 NC_011852.1 hypothetical protein 9094 7278619 HAPS_0004 Haemophilus parasuis SH0165 hypothetical protein YP_002474657.1 8972 R 557723 CDS YP_002474658.1 219870283 7278620 9632..11416 1 NC_011852.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 11416 frdA 7278620 frdA Haemophilus parasuis SH0165 fumarate reductase flavoprotein subunit YP_002474658.1 9632 D 557723 CDS YP_002474659.1 219870284 7278621 11423..12193 1 NC_011852.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 12193 frdB 7278621 frdB Haemophilus parasuis SH0165 fumarate reductase iron-sulfur subunit YP_002474659.1 11423 D 557723 CDS YP_002474660.1 219870285 7278622 12206..12598 1 NC_011852.1 COG:C;COG3029; fumarate reductase (anaerobic), membrane anchor subunit C 12598 frdC 7278622 frdC Haemophilus parasuis SH0165 fumarate reductase (anaerobic), membrane anchor subunit C YP_002474660.1 12206 D 557723 CDS YP_002474661.1 219870286 7278623 12609..12953 1 NC_011852.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 12953 frdD 7278623 frdD Haemophilus parasuis SH0165 fumarate reductase subunit D YP_002474661.1 12609 D 557723 CDS YP_002474662.1 219870287 7278624 complement(13272..14027) 1 NC_011852.1 putative role in sulfur assimilation; putative sulfate transport protein CysZ 14027 cysZ 7278624 cysZ Haemophilus parasuis SH0165 putative sulfate transport protein CysZ YP_002474662.1 13272 R 557723 CDS YP_002474663.1 219870288 7278625 14136..14954 1 NC_011852.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 14954 zipA 7278625 zipA Haemophilus parasuis SH0165 cell division protein ZipA YP_002474663.1 14136 D 557723 CDS YP_002474664.1 219870289 7278626 15018..17045 1 NC_011852.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 17045 ligA 7278626 ligA Haemophilus parasuis SH0165 NAD-dependent DNA ligase LigA YP_002474664.1 15018 D 557723 CDS YP_002474665.1 219870290 7278627 complement(17103..18932) 1 NC_011852.1 COG:L;COG0514; ATP-dependent DNA helicase RecQ, superfamily II 18932 recQ 7278627 recQ Haemophilus parasuis SH0165 ATP-dependent DNA helicase RecQ, superfamily II YP_002474665.1 17103 R 557723 CDS YP_002474666.1 219870291 7278628 complement(18932..19240) 1 NC_011852.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 19240 cyaY 7278628 cyaY Haemophilus parasuis SH0165 frataxin-like protein YP_002474666.1 18932 R 557723 CDS YP_002474667.1 219870292 7278629 complement(19323..19952) 1 NC_011852.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 19952 lexA 7278629 lexA Haemophilus parasuis SH0165 LexA repressor YP_002474667.1 19323 R 557723 CDS YP_002474668.1 219870293 7278630 complement(20146..21147) 1 NC_011852.1 pyruvate kinase/FOG: TPR repeat, Sel1 subfamily 21147 pykF 7278630 pykF Haemophilus parasuis SH0165 pyruvate kinase/FOG: TPR repeat, Sel1 subfamily YP_002474668.1 20146 R 557723 CDS YP_002474669.1 219870294 7278631 complement(21151..21735) 1 NC_011852.1 hypothetical protein 21735 7278631 HAPS_0016 Haemophilus parasuis SH0165 hypothetical protein YP_002474669.1 21151 R 557723 CDS YP_002474670.1 219870295 7278632 complement(21737..22492) 1 NC_011852.1 COG:R;COG0790; Sel1 domain protein, repeat-containing protein 22492 7278632 HAPS_0017 Haemophilus parasuis SH0165 Sel1 domain protein, repeat-containing protein YP_002474670.1 21737 R 557723 CDS YP_002474671.1 219870296 7278633 22799..25234 1 NC_011852.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 25234 plsB 7278633 plsB Haemophilus parasuis SH0165 glycerol-3-phosphate acyltransferase YP_002474671.1 22799 D 557723 CDS YP_002474672.1 219870297 7278634 25428..25970 1 NC_011852.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 25970 apt 7278634 apt Haemophilus parasuis SH0165 adenine phosphoribosyltransferase YP_002474672.1 25428 D 557723 CDS YP_002474673.1 219870298 7278635 26035..28047 1 NC_011852.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 28047 dnaX 7278635 dnaX Haemophilus parasuis SH0165 DNA polymerase III subunits gamma and tau YP_002474673.1 26035 D 557723 CDS YP_002474674.1 219870299 7278636 28053..28949 1 NC_011852.1 COG:V;COG1131; multidrug ABC transporter ATPase 28949 7278636 HAPS_0021 Haemophilus parasuis SH0165 multidrug ABC transporter ATPase YP_002474674.1 28053 D 557723 CDS YP_002474675.1 219870300 7278637 28971..29726 1 NC_011852.1 COG:V;COG0842; multidrug ABC transporter permease 29726 7278637 HAPS_0022 Haemophilus parasuis SH0165 multidrug ABC transporter permease YP_002474675.1 28971 D 557723 CDS YP_002474676.1 219870301 7278638 29816..30097 1 NC_011852.1 COG:D;COG2161; putative plasmid stability protein StbD, antitoxin of toxin-antitoxin stability system 30097 stbD 7278638 stbD Haemophilus parasuis SH0165 putative plasmid stability protein StbD, antitoxin of toxin-antitoxin stability system YP_002474676.1 29816 D 557723 CDS YP_002474677.1 219870302 7278639 30094..30378 1 NC_011852.1 COG:JD;COG2026; putative plasmid stability protein StbE, addiction module antitoxin 30378 stbE 7278639 stbE Haemophilus parasuis SH0165 putative plasmid stability protein StbE, addiction module antitoxin YP_002474677.1 30094 D 557723 CDS YP_002474678.1 219870303 7278640 30765..32138 1 NC_011852.1 COG:L;COG2925; exonuclease I 32138 sbcB 7278640 sbcB Haemophilus parasuis SH0165 exonuclease I YP_002474678.1 30765 D 557723 CDS YP_002474679.1 219870304 7278641 32221..33180 1 NC_011852.1 COG:S;COG1912; hypothetical protein 33180 7278641 HAPS_0026 Haemophilus parasuis SH0165 hypothetical protein YP_002474679.1 32221 D 557723 CDS YP_002474680.1 219870305 7278642 33329..34150 1 NC_011852.1 COG:R;COG0613; metal-dependent phosphoesterase 34150 trpH 7278642 trpH Haemophilus parasuis SH0165 metal-dependent phosphoesterase YP_002474680.1 33329 D 557723 CDS YP_002474681.1 219870306 7278643 complement(34257..34748) 1 NC_011852.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 34748 ilvH 7278643 ilvH Haemophilus parasuis SH0165 acetolactate synthase 3 regulatory subunit YP_002474681.1 34257 R 557723 CDS YP_002474682.1 219870307 7278644 complement(34741..36438) 1 NC_011852.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 3 catalytic subunit 36438 ilvI 7278644 ilvI Haemophilus parasuis SH0165 acetolactate synthase 3 catalytic subunit YP_002474682.1 34741 R 557723 CDS YP_002474683.1 219870308 7278645 36776..37858 1 NC_011852.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 37858 leuB 7278645 leuB Haemophilus parasuis SH0165 3-isopropylmalate dehydrogenase YP_002474683.1 36776 D 557723 CDS YP_002474684.1 219870309 7278646 complement(38174..41263) 1 NC_011852.1 COG:V;COG0841; acriflavine resistance protein, cation/multidrug efflux pump 41263 acrB 7278646 acrB Haemophilus parasuis SH0165 acriflavine resistance protein, cation/multidrug efflux pump YP_002474684.1 38174 R 557723 CDS YP_002474685.1 219870310 7278647 complement(41275..42480) 1 NC_011852.1 COG:M;COG0845; putative acridine efflux pump AcrA, RND efflux membrane-fusion protein 42480 acrA 7278647 acrA Haemophilus parasuis SH0165 putative acridine efflux pump AcrA, RND efflux membrane-fusion protein YP_002474685.1 41275 R 557723 CDS YP_002474686.1 219870311 7278648 complement(42503..43084) 1 NC_011852.1 COG:K;COG1309; transcriptional regulator acrR protein 43084 acrR 7278648 acrR Haemophilus parasuis SH0165 transcriptional regulator acrR protein YP_002474686.1 42503 R 557723 CDS YP_002474687.1 219870312 7278649 43443..45041 1 NC_011852.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 45041 purH 7278649 purH Haemophilus parasuis SH0165 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002474687.1 43443 D 557723 CDS YP_002474688.1 219870313 7278650 complement(45117..46307) 1 NC_011852.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 46307 metC 7278650 metC Haemophilus parasuis SH0165 cystathionine beta-lyase YP_002474688.1 45117 R 557723 CDS YP_002474689.1 219870314 7278651 complement(46304..46867) 1 NC_011852.1 COG:L;COG0350; methylated-DNA--protein-cysteine methyltransferase 46867 ogt 7278651 ogt Haemophilus parasuis SH0165 methylated-DNA--protein-cysteine methyltransferase YP_002474689.1 46304 R 557723 CDS YP_002474690.1 219870315 7277389 complement(47253..48542) 1 NC_011852.1 COG:I;COG2067; long-chain fatty acid transport protein P1/47 kDa outer membrane protein 48542 ompP1 7277389 ompP1 Haemophilus parasuis SH0165 long-chain fatty acid transport protein P1/47 kDa outer membrane protein YP_002474690.1 47253 R 557723 CDS YP_002474691.1 219870316 7276844 48840..49115 1 NC_011852.1 COG:S;COG3691; putative DNA mismatch repair protein 49115 mutS 7276844 mutS Haemophilus parasuis SH0165 putative DNA mismatch repair protein YP_002474691.1 48840 D 557723 CDS YP_002474692.1 219870317 7276845 49279..49749 1 NC_011852.1 COG:S;COG4636; hypothetical protein 49749 7276845 HAPS_0039 Haemophilus parasuis SH0165 hypothetical protein YP_002474692.1 49279 D 557723 CDS YP_002474693.1 219870318 7276846 50051..50731 1 NC_011852.1 COG:M;COG1083; CMP-N-acetylneuraminic acid synthetase 50731 neuA 7276846 neuA Haemophilus parasuis SH0165 CMP-N-acetylneuraminic acid synthetase YP_002474693.1 50051 D 557723 CDS YP_002474694.1 219870319 7276847 50718..51914 1 NC_011852.1 involved in the export of O-antigen and teichoic acid/lipopolysaccharide biosynthesis protein; COG:R;COG2244; putative lipooligosaccharide flippase 51914 lsgA 7276847 lsgA Haemophilus parasuis SH0165 putative lipooligosaccharide flippase YP_002474694.1 50718 D 557723 CDS YP_002474695.1 219870320 7276848 51915..52883 1 NC_011852.1 CMP-N-acetylneuraminate-beta-galactosamide- alpha-2, 3-sialyltransferase/lipopolysaccharide biosynthesis protein 52883 lsgB 7276848 lsgB Haemophilus parasuis SH0165 CMP-N-acetylneuraminate-beta-galactosamide- alpha-2, 3-sialyltransferase/lipopolysaccharide biosynthesis protein YP_002474695.1 51915 D 557723 CDS YP_002474696.1 219870321 7276849 52895..53902 1 NC_011852.1 hypothetical protein 53902 7276849 HAPS_0043 Haemophilus parasuis SH0165 hypothetical protein YP_002474696.1 52895 D 557723 CDS YP_002474697.1 219870322 7276850 54105..55136 1 NC_011852.1 glycosyltransferase/capsular polysaccharide phosphotransferase WcwK 55136 wcwK 7276850 wcwK Haemophilus parasuis SH0165 glycosyltransferase/capsular polysaccharide phosphotransferase WcwK YP_002474697.1 54105 D 557723 CDS YP_002474698.1 219870323 7276851 55154..55972 1 NC_011852.1 COG:M;COG0463; extracellular polysaccharide glycosyltransferase 55972 wcfQ 7276851 wcfQ Haemophilus parasuis SH0165 extracellular polysaccharide glycosyltransferase YP_002474698.1 55154 D 557723 CDS YP_002474699.1 219870324 7276852 55980..57131 1 NC_011852.1 involved in lipopolysaccharide biosynthesis, spore coat polysaccharide biosynthesis protein C/glycosyltransferase; COG:M;COG0399; DegT/DnrJ/EryC1/StrS aminotransferase 57131 wbgX 7276852 wbgX Haemophilus parasuis SH0165 DegT/DnrJ/EryC1/StrS aminotransferase YP_002474699.1 55980 D 557723 CDS YP_002474700.1 219870325 7276853 57145..57738 1 NC_011852.1 COG:M;COG2148; putative glycosyltransferase/lipopolysaccharide biosynthesis protein 57738 wbgY 7276853 wbgY Haemophilus parasuis SH0165 putative glycosyltransferase/lipopolysaccharide biosynthesis protein YP_002474700.1 57145 D 557723 CDS YP_002474701.1 219870326 7276854 58104..60044 1 NC_011852.1 COG:MG;COG1086; polysaccharide biosynthesis protein CapD 60044 capD 7276854 capD Haemophilus parasuis SH0165 polysaccharide biosynthesis protein CapD YP_002474701.1 58104 D 557723 CDS YP_002474702.1 219870327 7276855 60308..61462 1 NC_011852.1 COG:M;COG1596; polysaccharide export protein, periplasmic protein involved in capsular polysaccharide export 61462 wza 7276855 wza Haemophilus parasuis SH0165 polysaccharide export protein, periplasmic protein involved in capsular polysaccharide export YP_002474702.1 60308 D 557723 CDS YP_002474703.1 219870328 7276856 61466..61909 1 NC_011852.1 COG:T;COG0394; cytoplasmic tyrosine phosphatase 61909 ptp 7276856 ptp Haemophilus parasuis SH0165 cytoplasmic tyrosine phosphatase YP_002474703.1 61466 D 557723 CDS YP_002474704.1 219870329 7276857 61928..64015 1 NC_011852.1 COG:M;COG3206; tyrosine kinase, chain length regulator in capsular polysaccharide biosynthesis 64015 wzs 7276857 wzs Haemophilus parasuis SH0165 tyrosine kinase, chain length regulator in capsular polysaccharide biosynthesis YP_002474704.1 61928 D 557723 CDS YP_002474705.1 219870330 7276858 64250..64696 1 NC_011852.1 COG:K;COG1959; BadM/Rrf2 family HTH-type transcriptional regulator 64696 7276858 HAPS_0052 Haemophilus parasuis SH0165 BadM/Rrf2 family HTH-type transcriptional regulator YP_002474705.1 64250 D 557723 CDS YP_002474706.1 219870331 7276859 64728..65948 1 NC_011852.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 65948 iscS 7276859 iscS Haemophilus parasuis SH0165 cysteine desulfurase YP_002474706.1 64728 D 557723 CDS YP_002474707.1 219870332 7276860 66114..66497 1 NC_011852.1 COG:C;COG0822; scaffold protein, NifU-like protein involved in Fe-S cluster formation 66497 iscU 7276860 iscU Haemophilus parasuis SH0165 scaffold protein, NifU-like protein involved in Fe-S cluster formation YP_002474707.1 66114 D 557723 CDS YP_002474708.1 219870333 7276861 66828..67151 1 NC_011852.1 COG:S;COG0316; iron-binding protein, HesB family iron-sulfur (Fe-S) cluster formation protein 67151 iscA 7276861 iscA Haemophilus parasuis SH0165 iron-binding protein, HesB family iron-sulfur (Fe-S) cluster formation protein YP_002474708.1 66828 D 557723 CDS YP_002474709.1 219870334 7276862 67161..67682 1 NC_011852.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 67682 hscB 7276862 hscB Haemophilus parasuis SH0165 co-chaperone HscB YP_002474709.1 67161 D 557723 CDS YP_002474710.1 219870335 7276863 67947..68918 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 68918 7276863 HAPS_0057 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002474710.1 67947 D 557723 CDS YP_002474711.1 219870336 7276864 68965..69600 1 NC_011852.1 hypothetical protein 69600 hisS 7276864 hisS Haemophilus parasuis SH0165 hypothetical protein YP_002474711.1 68965 D 557723 CDS YP_002474712.1 219870337 7276865 69775..71451 1 NC_011852.1 COG:O;COG0443; chaperone protein HscA 71451 hscA 7276865 hscA Haemophilus parasuis SH0165 chaperone protein HscA YP_002474712.1 69775 D 557723 CDS YP_002474713.1 219870338 7276866 71727..72068 1 NC_011852.1 COG:C;COG0633; ferredoxin, 2Fe-2S type, ISC system 72068 fdx 7276866 fdx Haemophilus parasuis SH0165 ferredoxin, 2Fe-2S type, ISC system YP_002474713.1 71727 D 557723 CDS YP_002474714.1 219870339 7276867 72068..72262 1 NC_011852.1 COG:S;COG2975; FeS assembly protein IscX 72262 iscX 7276867 iscX Haemophilus parasuis SH0165 FeS assembly protein IscX YP_002474714.1 72068 D 557723 CDS YP_002474715.1 219870340 7276869 complement(73068..73577) 1 NC_011852.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 73577 luxS 7276869 luxS Haemophilus parasuis SH0165 S-ribosylhomocysteinase YP_002474715.1 73068 R 557723 CDS YP_002474716.1 219870341 7276870 73841..75688 1 NC_011852.1 COG:T;COG1217; GTP-binding protein/membrane GTPase involved in stress response 75688 typA 7276870 typA Haemophilus parasuis SH0165 GTP-binding protein/membrane GTPase involved in stress response YP_002474716.1 73841 D 557723 CDS YP_002474717.1 219870342 7276871 75737..76000 1 NC_011852.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 76000 grxA 7276871 grxA Haemophilus parasuis SH0165 glutaredoxin YP_002474717.1 75737 D 557723 CDS YP_002474718.1 219870343 7276872 complement(76392..76736) 1 NC_011852.1 hypothetical protein 76736 7276872 HAPS_0066 Haemophilus parasuis SH0165 hypothetical protein YP_002474718.1 76392 R 557723 CDS YP_002474719.1 219870344 7276873 77166..78716 1 NC_011852.1 COG:C;COG1271; cytochrome D ubiquinol oxidase subunit I 78716 cydA 7276873 cydA Haemophilus parasuis SH0165 cytochrome D ubiquinol oxidase subunit I YP_002474719.1 77166 D 557723 CDS YP_002474720.1 219870345 7276874 78730..79878 1 NC_011852.1 COG:C;COG1294; cytochrome D ubiquinol oxidase subunit II 79878 cydB 7276874 cydB Haemophilus parasuis SH0165 cytochrome D ubiquinol oxidase subunit II YP_002474720.1 78730 D 557723 CDS YP_002474721.1 219870346 7276875 79990..80280 1 NC_011852.1 COG:S;COG3790; hypothetical protein 80280 7276875 HAPS_0069 Haemophilus parasuis SH0165 hypothetical protein YP_002474721.1 79990 D 557723 CDS YP_002474722.1 219870347 7276876 80450..80848 1 NC_011852.1 COG:R;COG0824; Pol-Pal system-associated acyl-CoA thioesterase 80848 ybgC 7276876 ybgC Haemophilus parasuis SH0165 Pol-Pal system-associated acyl-CoA thioesterase YP_002474722.1 80450 D 557723 CDS YP_002474723.1 219870348 7276877 80873..81553 1 NC_011852.1 COG:U;COG0811; colicin transport protein/biopolymer transport protein, membrane spanning protein in TolA-TolQ-TolR complex 81553 tolQ 7276877 tolQ Haemophilus parasuis SH0165 colicin transport protein/biopolymer transport protein, membrane spanning protein in TolA-TolQ-TolR complex YP_002474723.1 80873 D 557723 CDS YP_002474724.1 219870349 7276878 81619..82059 1 NC_011852.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 82059 tolR 7276878 tolR Haemophilus parasuis SH0165 colicin uptake protein TolR YP_002474724.1 81619 D 557723 CDS YP_002474725.1 219870350 7276879 82076..83377 1 NC_011852.1 involved in colicin uptake, membrane spanning protein in TolA-TolQ-TolR complex; cell envelope integrity inner membrane protein TolA 83377 tolA 7276879 tolA Haemophilus parasuis SH0165 cell envelope integrity inner membrane protein TolA YP_002474725.1 82076 D 557723 CDS YP_002474726.1 219870351 7276880 83508..84683 1 NC_011852.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 84683 tolB 7276880 tolB Haemophilus parasuis SH0165 translocation protein TolB YP_002474726.1 83508 D 557723 CDS YP_002474727.1 219870352 7276881 84702..85163 1 NC_011852.1 COG:M;COG2885; 18K peptidoglycan-associated outer membrane lipoprotein PalA 85163 palA 7276881 palA Haemophilus parasuis SH0165 18K peptidoglycan-associated outer membrane lipoprotein PalA YP_002474727.1 84702 D 557723 CDS YP_002474728.1 219870353 7276882 85309..86169 1 NC_011852.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 86169 djlA 7276882 djlA Haemophilus parasuis SH0165 Dna-J like membrane chaperone protein YP_002474728.1 85309 D 557723 CDS YP_002474729.1 219870354 7276883 86169..86792 1 NC_011852.1 COG:S;COG3647; inner membrane protein 86792 yjdF 7276883 yjdF Haemophilus parasuis SH0165 inner membrane protein YP_002474729.1 86169 D 557723 CDS YP_002474730.1 219870355 7276884 86841..87761 1 NC_011852.1 COG:J;COG0042; tRNA-dihydrouridine synthase C 87761 dusC 7276884 dusC Haemophilus parasuis SH0165 tRNA-dihydrouridine synthase C YP_002474730.1 86841 D 557723 CDS YP_002474731.1 219870356 7276885 87761..88807 1 NC_011852.1 COG:S;COG3768; hypothetical protein 88807 7276885 HAPS_0079 Haemophilus parasuis SH0165 hypothetical protein YP_002474731.1 87761 D 557723 CDS YP_002474732.1 219870357 7276886 89082..89870 1 NC_011852.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 89870 truA 7276886 truA Haemophilus parasuis SH0165 tRNA pseudouridine synthase A YP_002474732.1 89082 D 557723 CDS YP_002474733.1 219870358 7276887 89939..91414 1 NC_011852.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 91414 cafA 7276887 cafA Haemophilus parasuis SH0165 ribonuclease G YP_002474733.1 89939 D 557723 CDS YP_002474734.1 219870359 7276888 91573..92613 1 NC_011852.1 COG:E;COG0687; spermidine/putrescine-binding periplasmic protein 1 92613 potD 7276888 potD Haemophilus parasuis SH0165 spermidine/putrescine-binding periplasmic protein 1 YP_002474734.1 91573 D 557723 CDS YP_002474735.1 219870360 7276889 92751..93329 1 NC_011852.1 COG:S;COG3117; hypothetical protein 93329 7276889 HAPS_0083 Haemophilus parasuis SH0165 hypothetical protein YP_002474735.1 92751 D 557723 CDS YP_002474736.1 219870361 7276890 93355..93858 1 NC_011852.1 COG:S;COG1934; hypothetical protein 93858 7276890 HAPS_0084 Haemophilus parasuis SH0165 hypothetical protein YP_002474736.1 93355 D 557723 CDS YP_002474737.1 219870362 7276891 93868..94593 1 NC_011852.1 COG:R;COG1137; ABC transporter ATPase 94593 7276891 HAPS_0085 Haemophilus parasuis SH0165 ABC transporter ATPase YP_002474737.1 93868 D 557723 CDS YP_002474738.1 219870363 7276892 94730..95176 1 NC_011852.1 COG:GT;COG1762; PTS system, nitrogen regulatory IIA-like protein 95176 ptsN 7276892 ptsN Haemophilus parasuis SH0165 PTS system, nitrogen regulatory IIA-like protein YP_002474738.1 94730 D 557723 CDS YP_002474739.1 219870364 7276893 95182..96027 1 NC_011852.1 COG:R;COG1660; putative P-loop-containing kinase 96027 7276893 HAPS_0087 Haemophilus parasuis SH0165 putative P-loop-containing kinase YP_002474739.1 95182 D 557723 CDS YP_002474740.1 219870365 7276894 96029..97210 1 NC_011852.1 COG:HC;COG0654; FAD-dependent monooxygenase 97210 visC 7276894 visC Haemophilus parasuis SH0165 FAD-dependent monooxygenase YP_002474740.1 96029 D 557723 CDS YP_002474741.1 219870366 7276895 97233..97817 1 NC_011852.1 lipoprotein HlpB, chromosome segregation ATPase 97817 hlpB 7276895 hlpB Haemophilus parasuis SH0165 lipoprotein HlpB, chromosome segregation ATPase YP_002474741.1 97233 D 557723 CDS YP_002474742.1 219870367 7276896 97902..99281 1 NC_011852.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 99281 cysS 7276896 cysS Haemophilus parasuis SH0165 cysteinyl-tRNA synthetase YP_002474742.1 97902 D 557723 CDS YP_002474743.1 219870368 7276898 complement(100304..101899) 1 NC_011852.1 COG:E;COG0747; heme-binding protein A 101899 hbpA 7276898 hbpA Haemophilus parasuis SH0165 heme-binding protein A YP_002474743.1 100304 R 557723 CDS YP_002474744.1 219870369 7276900 complement(102486..103274) 1 NC_011852.1 ferric hydroximate transport ferric iron reductase 103274 fhuF 7276900 fhuF Haemophilus parasuis SH0165 ferric hydroximate transport ferric iron reductase YP_002474744.1 102486 R 557723 CDS YP_002474745.1 219870370 7276903 complement(105099..107498) 1 NC_011852.1 COG:G;COG0058; glucan phosphorylase 107498 glgP 7276903 glgP Haemophilus parasuis SH0165 glucan phosphorylase YP_002474745.1 105099 R 557723 CDS YP_002474746.1 219870371 7276904 complement(107658..107822) 1 NC_011852.1 hypothetical protein 107822 7276904 HAPS_0098 Haemophilus parasuis SH0165 hypothetical protein YP_002474746.1 107658 R 557723 CDS YP_002474747.1 219870372 7276905 complement(107831..108370) 1 NC_011852.1 COG:O;COG1495; disulfide bond formation protein B 108370 dsbB 7276905 dsbB Haemophilus parasuis SH0165 disulfide bond formation protein B YP_002474747.1 107831 R 557723 CDS YP_002474748.1 219870373 7276907 110094..110816 1 NC_011852.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 110816 fadR 7276907 fadR Haemophilus parasuis SH0165 fatty acid metabolism regulator YP_002474748.1 110094 D 557723 CDS YP_002474749.1 219870374 7276908 111012..112064 1 NC_011852.1 COG:H;COG1477; thiamine biosynthesis membrane-associated lipoprotein 112064 apbE 7276908 apbE Haemophilus parasuis SH0165 thiamine biosynthesis membrane-associated lipoprotein YP_002474749.1 111012 D 557723 CDS YP_002474750.1 219870375 7276909 112076..112330 1 NC_011852.1 COG:S;COG2991; hypothetical protein 112330 7276909 HAPS_0103 Haemophilus parasuis SH0165 hypothetical protein YP_002474750.1 112076 D 557723 CDS YP_002474751.1 219870376 7276910 112355..112777 1 NC_011852.1 nucleotidyltransferase substrate binding protein 112777 7276910 HAPS_0104 Haemophilus parasuis SH0165 nucleotidyltransferase substrate binding protein YP_002474751.1 112355 D 557723 CDS YP_002474752.1 219870377 7276911 112756..113076 1 NC_011852.1 DNA polymerase beta domain-containing protein region 113076 7276911 HAPS_0105 Haemophilus parasuis SH0165 DNA polymerase beta domain-containing protein region YP_002474752.1 112756 D 557723 CDS YP_002474753.1 219870378 7276912 113076..114227 1 NC_011852.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 114227 mnmA 7276912 mnmA Haemophilus parasuis SH0165 tRNA-specific 2-thiouridylase MnmA YP_002474753.1 113076 D 557723 CDS YP_002474754.1 219870379 7276913 complement(114423..116270) 1 NC_011852.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 116270 dxs 7276913 dxs Haemophilus parasuis SH0165 1-deoxy-D-xylulose-5-phosphate synthase YP_002474754.1 114423 R 557723 CDS YP_002474755.1 219870380 7276914 complement(116323..117135) 1 NC_011852.1 COG:G;COG0483; inositol-1-monophosphatase 117135 suhB 7276914 suhB Haemophilus parasuis SH0165 inositol-1-monophosphatase YP_002474755.1 116323 R 557723 CDS YP_002474756.1 219870381 7276915 117532..118503 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 118503 7276915 HAPS_0109 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002474756.1 117532 D 557723 CDS YP_002474757.1 219870382 7276916 119050..119508 1 NC_011852.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 119508 mraZ 7276916 mraZ Haemophilus parasuis SH0165 cell division protein MraZ YP_002474757.1 119050 D 557723 CDS YP_002474758.1 219870383 7276917 119527..120465 1 NC_011852.1 COG:M;COG0275; S-adenosyl-methyltransferase MraW 120465 mraW 7276917 mraW Haemophilus parasuis SH0165 S-adenosyl-methyltransferase MraW YP_002474758.1 119527 D 557723 CDS YP_002474759.1 219870384 7276918 120465..120776 1 NC_011852.1 COG:D;COG3116; cell division protein FtsL 120776 ftsL 7276918 ftsL Haemophilus parasuis SH0165 cell division protein FtsL YP_002474759.1 120465 D 557723 CDS YP_002474760.1 219870385 7276919 120779..122830 1 NC_011852.1 COG:M;COG0768; cell division protein FtsI 122830 ftsI 7276919 ftsI Haemophilus parasuis SH0165 cell division protein FtsI YP_002474760.1 120779 D 557723 CDS YP_002474761.1 219870386 7276920 122840..124330 1 NC_011852.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 124330 murE 7276920 murE Haemophilus parasuis SH0165 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002474761.1 122840 D 557723 CDS YP_002474762.1 219870387 7276921 124475..125869 1 NC_011852.1 COG:M;COG0770; UDP-MurNAc-pentapeptide synthetase 125869 murF 7276921 murF Haemophilus parasuis SH0165 UDP-MurNAc-pentapeptide synthetase YP_002474762.1 124475 D 557723 CDS YP_002474763.1 219870388 7276922 125880..126962 1 NC_011852.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 126962 mraY 7276922 mraY Haemophilus parasuis SH0165 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002474763.1 125880 D 557723 CDS YP_002474764.1 219870389 7276923 127085..128383 1 NC_011852.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 128383 murD 7276923 murD Haemophilus parasuis SH0165 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002474764.1 127085 D 557723 CDS YP_002474765.1 219870390 7276924 128383..129561 1 NC_011852.1 COG:D;COG0772; cell division membrane protein 129561 ftsW 7276924 ftsW Haemophilus parasuis SH0165 cell division membrane protein YP_002474765.1 128383 D 557723 CDS YP_002474766.1 219870391 7276762 129576..130631 1 NC_011852.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 130631 murG 7276762 murG Haemophilus parasuis SH0165 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_002474766.1 129576 D 557723 CDS YP_002474767.1 219870392 7276760 130684..132111 1 NC_011852.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 132111 murC 7276760 murC Haemophilus parasuis SH0165 UDP-N-acetylmuramate--L-alanine ligase YP_002474767.1 130684 D 557723 CDS YP_002474768.1 219870393 7277963 132259..133170 1 NC_011852.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 133170 ddl 7277963 ddl Haemophilus parasuis SH0165 D-alanine--D-alanine ligase YP_002474768.1 132259 D 557723 CDS YP_002474769.1 219870394 7277964 133170..133949 1 NC_011852.1 COG:M;COG1589; cell division septal protein FtsQ 133949 ftsQ 7277964 ftsQ Haemophilus parasuis SH0165 cell division septal protein FtsQ YP_002474769.1 133170 D 557723 CDS YP_002474770.1 219870395 7277965 133976..135253 1 NC_011852.1 COG:D;COG0849; cell division protein FtsA/actin-like ATPase involved in cell division 135253 ftsA 7277965 ftsA Haemophilus parasuis SH0165 cell division protein FtsA/actin-like ATPase involved in cell division YP_002474770.1 133976 D 557723 CDS YP_002474771.1 219870396 7277966 135296..136522 1 NC_011852.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 136522 ftsZ 7277966 ftsZ Haemophilus parasuis SH0165 cell division protein FtsZ YP_002474771.1 135296 D 557723 CDS YP_002474772.1 219870397 7277967 136548..137468 1 NC_011852.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 137468 lpxC 7277967 lpxC Haemophilus parasuis SH0165 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002474772.1 136548 D 557723 CDS YP_002474773.1 219870398 7277968 137658..138872 1 NC_011852.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 138872 sstT 7277968 sstT Haemophilus parasuis SH0165 serine/threonine transporter SstT YP_002474773.1 137658 D 557723 CDS YP_002474774.1 219870399 7277969 139145..140944 1 NC_011852.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 140944 lepA 7277969 lepA Haemophilus parasuis SH0165 GTP-binding protein LepA YP_002474774.1 139145 D 557723 CDS YP_002474775.1 219870400 7277970 141203..142174 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 142174 7277970 HAPS_0128 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002474775.1 141203 D 557723 CDS YP_002474776.1 219870401 7277971 142250..143212 1 NC_011852.1 COG:U;COG0681; signal peptidase I 143212 lepB 7277971 lepB Haemophilus parasuis SH0165 signal peptidase I YP_002474776.1 142250 D 557723 CDS YP_002474777.1 219870402 7277972 143345..144016 1 NC_011852.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 144016 rnc 7277972 rnc Haemophilus parasuis SH0165 ribonuclease III YP_002474777.1 143345 D 557723 CDS YP_002474778.1 219870403 7277973 144077..144979 1 NC_011852.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 144979 era 7277973 era Haemophilus parasuis SH0165 GTP-binding protein Era YP_002474778.1 144077 D 557723 CDS YP_002474779.1 219870404 7277974 144979..145698 1 NC_011852.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 145698 recO 7277974 recO Haemophilus parasuis SH0165 DNA repair protein RecO YP_002474779.1 144979 D 557723 CDS YP_002474780.1 219870405 7277975 complement(145803..146330) 1 NC_011852.1 COG:L;COG1943; hypothetical protein 146330 7277975 HAPS_0133 Haemophilus parasuis SH0165 hypothetical protein YP_002474780.1 145803 R 557723 CDS YP_002474781.1 219870406 7277976 complement(146581..147654) 1 NC_011852.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 147654 metX 7277976 metX Haemophilus parasuis SH0165 homoserine O-acetyltransferase YP_002474781.1 146581 R 557723 CDS YP_002474782.1 219870407 7277978 149526..150239 1 NC_011852.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 150239 pyrH 7277978 pyrH Haemophilus parasuis SH0165 uridylate kinase YP_002474782.1 149526 D 557723 CDS YP_002474783.1 219870408 7277979 complement(150301..150879) 1 NC_011852.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 150879 gmhA 7277979 gmhA Haemophilus parasuis SH0165 phosphoheptose isomerase YP_002474783.1 150301 R 557723 CDS YP_002474784.1 219870409 7277980 151009..151566 1 NC_011852.1 COG:J;COG0233; ribosome recycling factor 151566 frr 7277980 frr Haemophilus parasuis SH0165 ribosome recycling factor YP_002474784.1 151009 D 557723 CDS YP_002474785.1 219870410 7277981 151710..152429 1 NC_011852.1 hypothetical protein 152429 7277981 HAPS_0139 Haemophilus parasuis SH0165 hypothetical protein YP_002474785.1 151710 D 557723 CDS YP_002474786.1 219870411 7277982 complement(152562..153788) 1 NC_011852.1 COG:R;COG2252; putative xanthine/uracil permease 153788 7277982 HAPS_0140 Haemophilus parasuis SH0165 putative xanthine/uracil permease YP_002474786.1 152562 R 557723 CDS YP_002474787.1 219870412 7277983 complement(154045..155085) 1 NC_011852.1 COG:R;COG0628; PerM protein permease 155085 perM 7277983 perM Haemophilus parasuis SH0165 PerM protein permease YP_002474787.1 154045 R 557723 CDS YP_002474788.1 219870413 7277984 complement(155158..156147) 1 NC_011852.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 156147 usg 7277984 usg Haemophilus parasuis SH0165 aspartate-semialdehyde dehydrogenase YP_002474788.1 155158 R 557723 CDS YP_002474789.1 219870414 7277985 complement(156290..156757) 1 NC_011852.1 COG:R;COG3030; FxsA protein affecting phage T7 exclusion by the F plasmid 156757 fxsA 7277985 fxsA Haemophilus parasuis SH0165 FxsA protein affecting phage T7 exclusion by the F plasmid YP_002474789.1 156290 R 557723 CDS YP_002474790.1 219870415 7277986 157300..158805 1 NC_011852.1 COG:EH;COG0028; acetolactate synthase 2 large subunit, biosynthetic type 158805 ilvG 7277986 ilvG Haemophilus parasuis SH0165 acetolactate synthase 2 large subunit, biosynthetic type YP_002474790.1 157300 D 557723 CDS YP_002474791.1 219870416 7277987 158817..159035 1 NC_011852.1 COG:S;COG3978; acetolactate synthase 2 regulatory subunit 159035 ilvM 7277987 ilvM Haemophilus parasuis SH0165 acetolactate synthase 2 regulatory subunit YP_002474791.1 158817 D 557723 CDS YP_002474792.1 219870417 7277989 complement(159611..159763) 1 NC_011852.1 hypothetical protein 159763 7277989 HAPS_0147 Haemophilus parasuis SH0165 hypothetical protein YP_002474792.1 159611 R 557723 CDS YP_002474793.1 219870418 7277991 164136..166190 1 NC_011852.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 166190 metG 7277991 metG Haemophilus parasuis SH0165 methionyl-tRNA synthetase YP_002474793.1 164136 D 557723 CDS YP_002474794.1 219870419 7277992 166246..166662 1 NC_011852.1 COG:F;COG0105; nucleoside diphosphate kinase 166662 ndk 7277992 ndk Haemophilus parasuis SH0165 nucleoside diphosphate kinase YP_002474794.1 166246 D 557723 CDS YP_002474795.1 219870420 7277993 complement(167525..167926) 1 NC_011852.1 hypothetical protein 167926 7277993 HAPS_0151 Haemophilus parasuis SH0165 hypothetical protein YP_002474795.1 167525 R 557723 CDS YP_002474796.1 219870421 7277994 complement(167913..168461) 1 NC_011852.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 168461 nudE 7277994 nudE Haemophilus parasuis SH0165 ADP-ribose diphosphatase NudE YP_002474796.1 167913 R 557723 CDS YP_002474797.1 219870422 7277995 complement(168510..168986) 1 NC_011852.1 COG:S;COG1238; hypothetical protein 168986 7277995 HAPS_0153 Haemophilus parasuis SH0165 hypothetical protein YP_002474797.1 168510 R 557723 CDS YP_002474798.1 219870423 7277996 169171..169995 1 NC_011852.1 COG:P;COG2116; FNT family formate-nitrite transporter 169995 focA 7277996 focA Haemophilus parasuis SH0165 FNT family formate-nitrite transporter YP_002474798.1 169171 D 557723 CDS YP_002474799.1 219870424 7277997 170089..172413 1 NC_011852.1 COG:C;COG1882; pyruvate-formate lyase 172413 pflB 7277997 pflB Haemophilus parasuis SH0165 pyruvate-formate lyase YP_002474799.1 170089 D 557723 CDS YP_002474800.1 219870425 7277998 172555..173295 1 NC_011852.1 COG:O;COG1180; pyruvate formate lyase-activating enzyme 1 173295 pflA 7277998 pflA Haemophilus parasuis SH0165 pyruvate formate lyase-activating enzyme 1 YP_002474800.1 172555 D 557723 CDS YP_002474801.1 219870426 7277999 complement(173488..174258) 1 NC_011852.1 hypothetical protein 174258 7277999 HAPS_0157 Haemophilus parasuis SH0165 hypothetical protein YP_002474801.1 173488 R 557723 CDS YP_002474802.1 219870427 7278000 complement(174471..176129) 1 NC_011852.1 COG:R;COG2985; hypothetical protein 176129 7278000 HAPS_0158 Haemophilus parasuis SH0165 hypothetical protein YP_002474802.1 174471 R 557723 CDS YP_002474803.1 219870428 7278001 176317..177321 1 NC_011852.1 COG:E;COG0786; sodium/glutamate symport carrier protein 177321 gltS 7278001 gltS Haemophilus parasuis SH0165 sodium/glutamate symport carrier protein YP_002474803.1 176317 D 557723 CDS YP_002474804.1 219870429 7278002 complement(177458..178177) 1 NC_011852.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 178177 bioD 7278002 bioD Haemophilus parasuis SH0165 dithiobiotin synthetase YP_002474804.1 177458 R 557723 CDS YP_002474805.1 219870430 7278003 complement(178357..178749) 1 NC_011852.1 COG:S;COG3105; hypothetical protein 178749 7278003 HAPS_0161 Haemophilus parasuis SH0165 hypothetical protein YP_002474805.1 178357 R 557723 CDS YP_002474806.1 219870431 7278004 179043..179471 1 NC_011852.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 179471 rplM 7278004 rplM Haemophilus parasuis SH0165 50S ribosomal protein L13 YP_002474806.1 179043 D 557723 CDS YP_002474807.1 219870432 7278005 179487..179882 1 NC_011852.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 179882 rpsI 7278005 rpsI Haemophilus parasuis SH0165 30S ribosomal protein S9 YP_002474807.1 179487 D 557723 CDS YP_002474808.1 219870433 7278006 180997..182088 1 NC_011852.1 COG:M;COG3203; outer membrane protein P2 (OMP P2) 182088 ompP2 7278006 ompP2 Haemophilus parasuis SH0165 outer membrane protein P2 (OMP P2) YP_002474808.1 180997 D 557723 CDS YP_002474809.1 219870434 7278007 complement(182164..182892) 1 NC_011852.1 COG:J;COG0565; tRNA/rRNA methyltransferase 182892 yfiF 7278007 yfiF Haemophilus parasuis SH0165 tRNA/rRNA methyltransferase YP_002474809.1 182164 R 557723 CDS YP_002474810.1 219870435 7278008 183018..184058 1 NC_011852.1 COG:P;COG1840; iron (Fe3+) ABC superfamily ATP binding cassette transporter, binding protein 184058 afuA 7278008 afuA Haemophilus parasuis SH0165 iron (Fe3+) ABC superfamily ATP binding cassette transporter, binding protein YP_002474810.1 183018 D 557723 CDS YP_002474811.1 219870436 7278009 complement(184225..184995) 1 NC_011852.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 184995 hlyX 7278009 hlyX Haemophilus parasuis SH0165 fumarate/nitrate reduction transcriptional regulator YP_002474811.1 184225 R 557723 CDS YP_002474812.1 219870437 7278010 185084..185191 1 NC_011852.1 hypothetical protein 185191 7278010 HAPS_0168 Haemophilus parasuis SH0165 hypothetical protein YP_002474812.1 185084 D 557723 CDS YP_002474813.1 219870438 7278011 185360..185998 1 NC_011852.1 COG:QR;COG0500; S-adenosyl-L-methionine-dependent methyltransferase 185998 yecO 7278011 yecO Haemophilus parasuis SH0165 S-adenosyl-L-methionine-dependent methyltransferase YP_002474813.1 185360 D 557723 CDS YP_002474814.1 219870439 7278012 186133..187581 1 NC_011852.1 COG:L;COG0305; replicative DNA helicase 187581 dnaB 7278012 dnaB Haemophilus parasuis SH0165 replicative DNA helicase YP_002474814.1 186133 D 557723 CDS YP_002474815.1 219870440 7278013 187583..187861 1 NC_011852.1 COG:S;COG3100; hypothetical protein 187861 7278013 HAPS_0171 Haemophilus parasuis SH0165 hypothetical protein YP_002474815.1 187583 D 557723 CDS YP_002474816.1 219870441 7278014 187861..188310 1 NC_011852.1 COG:K;COG1327; transcriptional repressor NrdR, consists of a Zn-ribbon and ATP-cone domains 188310 nrdR 7278014 nrdR Haemophilus parasuis SH0165 transcriptional repressor NrdR, consists of a Zn-ribbon and ATP-cone domains YP_002474816.1 187861 D 557723 CDS YP_002474817.1 219870442 7278015 complement(188318..189331) 1 NC_011852.1 COG:E;COG1509; lysine 2,3-aminomutase YodO family protein 189331 7278015 HAPS_0173 Haemophilus parasuis SH0165 lysine 2,3-aminomutase YodO family protein YP_002474817.1 188318 R 557723 CDS YP_002474818.1 219870443 7278016 complement(189355..189888) 1 NC_011852.1 hypothetical protein 189888 7278016 HAPS_0174 Haemophilus parasuis SH0165 hypothetical protein YP_002474818.1 189355 R 557723 CDS YP_002474819.1 219870444 7278017 190052..190618 1 NC_011852.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 190618 efp 7278017 efp Haemophilus parasuis SH0165 elongation factor P YP_002474819.1 190052 D 557723 CDS YP_002474820.1 219870445 7278018 complement(190642..190821) 1 NC_011852.1 putative cell division protein zapB 190821 zapB 7278018 zapB Haemophilus parasuis SH0165 putative cell division protein zapB YP_002474820.1 190642 R 557723 CDS YP_002474821.1 219870446 7278019 191147..191365 1 NC_011852.1 COG:S;COG3074; hypothetical protein 191365 7278019 HAPS_0177 Haemophilus parasuis SH0165 hypothetical protein YP_002474821.1 191147 D 557723 CDS YP_002474822.1 219870447 7278020 191516..192004 1 NC_011852.1 COG:F;COG1435; thymidine kinase 192004 tdk 7278020 tdk Haemophilus parasuis SH0165 thymidine kinase YP_002474822.1 191516 D 557723 CDS YP_002474823.1 219870448 7278021 192138..192785 1 NC_011852.1 COG:R;COG0637; 2-deoxyglucose-6-phosphatase 192785 yniC 7278021 yniC Haemophilus parasuis SH0165 2-deoxyglucose-6-phosphatase YP_002474823.1 192138 D 557723 CDS YP_002474824.1 219870449 7278022 192932..195796 1 NC_011852.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 195796 polA 7278022 polA Haemophilus parasuis SH0165 DNA polymerase I YP_002474824.1 192932 D 557723 CDS YP_002474825.1 219870450 7278023 complement(195864..196526) 1 NC_011852.1 COG:R;COG0670; integral membrane protein, transport protein 196526 yccA 7278023 yccA Haemophilus parasuis SH0165 integral membrane protein, transport protein YP_002474825.1 195864 R 557723 CDS YP_002474826.1 219870451 7278024 complement(196644..199217) 1 NC_011852.1 COG:O;COG0542; ATP-dependent Clp protease subunit B 199217 clpB 7278024 clpB Haemophilus parasuis SH0165 ATP-dependent Clp protease subunit B YP_002474826.1 196644 R 557723 CDS YP_002474827.1 219870452 7278025 complement(199520..200203) 1 NC_011852.1 COG:O;COG1651; thiol:disulfide interchange protein DsbC 200203 dsbC 7278025 dsbC Haemophilus parasuis SH0165 thiol:disulfide interchange protein DsbC YP_002474827.1 199520 R 557723 CDS YP_002474828.1 219870453 7278026 complement(200215..201708) 1 NC_011852.1 COG:M;COG0739; metalloprotease 201708 7278026 HAPS_0184 Haemophilus parasuis SH0165 metalloprotease YP_002474828.1 200215 R 557723 CDS YP_002474829.1 219870454 7278027 201984..202700 1 NC_011852.1 COG:P;COG1121; high-affinity zinc uptake system ATP-binding protein ZnuC 202700 znuC 7278027 znuC Haemophilus parasuis SH0165 high-affinity zinc uptake system ATP-binding protein ZnuC YP_002474829.1 201984 D 557723 CDS YP_002474830.1 219870455 7278028 202711..203496 1 NC_011852.1 COG:P;COG1108; high-affinity zinc uptake system membrane protein 203496 znuB 7278028 znuB Haemophilus parasuis SH0165 high-affinity zinc uptake system membrane protein YP_002474830.1 202711 D 557723 CDS YP_002474831.1 219870456 7278029 203620..204417 1 NC_011852.1 COG:R;COG0121; putative glutamine amidotransferase class-II 204417 glmS 7278029 glmS Haemophilus parasuis SH0165 putative glutamine amidotransferase class-II YP_002474831.1 203620 D 557723 CDS YP_002474832.1 219870457 7278030 complement(204462..205403) 1 NC_011852.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 205403 lacD 7278030 lacD Haemophilus parasuis SH0165 tagatose 1,6-diphosphate aldolase YP_002474832.1 204462 R 557723 CDS YP_002474833.1 219870458 7278031 complement(205414..205800) 1 NC_011852.1 COG:G;COG2893; PTS system transporter subunit IIA 205800 ptsEIIA 7278031 ptsEIIA Haemophilus parasuis SH0165 PTS system transporter subunit IIA YP_002474833.1 205414 R 557723 CDS YP_002474834.1 219870459 7278032 complement(205961..207751) 1 NC_011852.1 COG:G;COG1874; beta-galactosidase 207751 bgaC 7278032 bgaC Haemophilus parasuis SH0165 beta-galactosidase YP_002474834.1 205961 R 557723 CDS YP_002474835.1 219870460 7278033 complement(207930..208766) 1 NC_011852.1 COG:G;COG3716; PTS system, IIDcomponent 208766 ptsEIID 7278033 ptsEIID Haemophilus parasuis SH0165 PTS system, IIDcomponent YP_002474835.1 207930 R 557723 CDS YP_002474836.1 219870461 7278034 complement(208753..209628) 1 NC_011852.1 COG:G;COG3715; PTS system transporter subunit IIC 209628 ptsEIIC 7278034 ptsEIIC Haemophilus parasuis SH0165 PTS system transporter subunit IIC YP_002474836.1 208753 R 557723 CDS YP_002474837.1 219870462 7278035 complement(209642..210115) 1 NC_011852.1 COG:G;COG3444; PTS system transporter subunit IIB 210115 ptsEIIB 7278035 ptsEIIB Haemophilus parasuis SH0165 PTS system transporter subunit IIB YP_002474837.1 209642 R 557723 CDS YP_002474838.1 219870463 7278036 complement(210132..211262) 1 NC_011852.1 COG:M;COG2222; tagatose-6-phosphate ketose/aldose isomerase 211262 agaS 7278036 agaS Haemophilus parasuis SH0165 tagatose-6-phosphate ketose/aldose isomerase YP_002474838.1 210132 R 557723 CDS YP_002474839.1 219870464 7278037 complement(211314..212075) 1 NC_011852.1 COG:KG;COG1349; transcriptional repressor AgaR/DNA-binding transcriptional dual regulator 212075 agaR 7278037 agaR Haemophilus parasuis SH0165 transcriptional repressor AgaR/DNA-binding transcriptional dual regulator YP_002474839.1 211314 R 557723 CDS YP_002474840.1 219870465 7278038 212416..213333 1 NC_011852.1 Required for efficient pilin antigenic variation; recombination associated protein 213333 rdgC 7278038 rdgC Haemophilus parasuis SH0165 recombination associated protein YP_002474840.1 212416 D 557723 CDS YP_002474841.1 219870466 7278039 213587..215650 1 NC_011852.1 COG:P;COG1178; Fe3+ ABC transporter permease 215650 afuB 7278039 afuB Haemophilus parasuis SH0165 Fe3+ ABC transporter permease YP_002474841.1 213587 D 557723 CDS YP_002474842.1 219870467 7278040 215634..216689 1 NC_011852.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 216689 fbpC 7278040 fbpC Haemophilus parasuis SH0165 ferric transporter ATP-binding subunit YP_002474842.1 215634 D 557723 CDS YP_002474843.1 219870468 7278042 217115..217522 1 NC_011852.1 COG:S;COG0779; hypothetical protein 217522 7278042 HAPS_0200 Haemophilus parasuis SH0165 hypothetical protein YP_002474843.1 217115 D 557723 CDS YP_002474844.1 219870469 7278043 217537..219069 1 NC_011852.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 219069 nusA 7278043 nusA Haemophilus parasuis SH0165 transcription elongation factor NusA YP_002474844.1 217537 D 557723 CDS YP_002474845.1 219870470 7276676 219087..221648 1 NC_011852.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 221648 infB 7276676 infB Haemophilus parasuis SH0165 translation initiation factor IF-2 YP_002474845.1 219087 D 557723 CDS YP_002474846.1 219870471 7277390 221788..222048 1 NC_011852.1 hypothetical protein 222048 7277390 HAPS_0203 Haemophilus parasuis SH0165 hypothetical protein YP_002474846.1 221788 D 557723 CDS YP_002474847.1 219870472 7277391 222041..222418 1 NC_011852.1 putative phage associated protein 222418 7277391 HAPS_0204 Haemophilus parasuis SH0165 putative phage associated protein YP_002474847.1 222041 D 557723 CDS YP_002474848.1 219870473 7277394 complement(227629..228519) 1 NC_011852.1 COG:K;COG0583; putative HTH-type transcriptional regulator 228519 7277394 HAPS_0207 Haemophilus parasuis SH0165 putative HTH-type transcriptional regulator YP_002474848.1 227629 R 557723 CDS YP_002474849.1 219870474 7277395 228657..231269 1 NC_011852.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 231269 topA 7277395 topA Haemophilus parasuis SH0165 DNA topoisomerase I YP_002474849.1 228657 D 557723 CDS YP_002474850.1 219870475 7277396 complement(231316..233052) 1 NC_011852.1 COG:R;COG3083; putative sulfatase 233052 7277396 HAPS_0209 Haemophilus parasuis SH0165 putative sulfatase YP_002474850.1 231316 R 557723 CDS YP_002474851.1 219870476 7277397 complement(233054..233278) 1 NC_011852.1 COG:S;COG3082; hypothetical protein 233278 7277397 HAPS_0210 Haemophilus parasuis SH0165 hypothetical protein YP_002474851.1 233054 R 557723 CDS YP_002474852.1 219870477 7277398 complement(233482..234183) 1 NC_011852.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase 234183 kdkA 7277398 kdkA Haemophilus parasuis SH0165 3-deoxy-D-manno-octulosonic-acid kinase YP_002474852.1 233482 R 557723 CDS YP_002474853.1 219870478 7277400 235105..236556 1 NC_011852.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 236556 thiI 7277400 thiI Haemophilus parasuis SH0165 thiamine biosynthesis protein ThiI YP_002474853.1 235105 D 557723 CDS YP_002474854.1 219870479 7277401 236579..237940 1 NC_011852.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 237940 glmU 7277401 glmU Haemophilus parasuis SH0165 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002474854.1 236579 D 557723 CDS YP_002474855.1 219870480 7277402 238232..239197 1 NC_011852.1 COG:T;COG3026; periplasmic negative regulator of sigmaE 239197 rseB 7277402 rseB Haemophilus parasuis SH0165 periplasmic negative regulator of sigmaE YP_002474855.1 238232 D 557723 CDS YP_002474856.1 219870481 7277403 239194..239622 1 NC_011852.1 COG:T;COG3086; sigma-E factor regulatory protein 239622 rseC 7277403 rseC Haemophilus parasuis SH0165 sigma-E factor regulatory protein YP_002474856.1 239194 D 557723 CDS YP_002474857.1 219870482 7277404 239633..241333 1 NC_011852.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 241333 lcfA 7277404 lcfA Haemophilus parasuis SH0165 long-chain-fatty-acid--CoA ligase YP_002474857.1 239633 D 557723 CDS YP_002474858.1 219870483 7277405 241442..242596 1 NC_011852.1 COG:D;COG4942; membrane-bound metallopeptidase 242596 7277405 HAPS_0218 Haemophilus parasuis SH0165 membrane-bound metallopeptidase YP_002474858.1 241442 D 557723 CDS YP_002474859.1 219870484 7277406 242598..243443 1 NC_011852.1 COG:S;COG2861; hypothetical protein 243443 7277406 HAPS_0219 Haemophilus parasuis SH0165 hypothetical protein YP_002474859.1 242598 D 557723 CDS YP_002474860.1 219870485 7277407 243473..245206 1 NC_011852.1 COG:M;COG0729; surface antigen (D15), outer membrane protein 245206 ompD15 7277407 ompD15 Haemophilus parasuis SH0165 surface antigen (D15), outer membrane protein YP_002474860.1 243473 D 557723 CDS YP_002474861.1 219870486 7277408 245219..249124 1 NC_011852.1 COG:S;COG2911; putative tubulin binding protein 249124 7277408 HAPS_0221 Haemophilus parasuis SH0165 putative tubulin binding protein YP_002474861.1 245219 D 557723 CDS YP_002474862.1 219870487 7277409 249362..249898 1 NC_011852.1 AbiQ-like protein/lactococcal phage abortive infection protein 249898 abiQ 7277409 abiQ Haemophilus parasuis SH0165 AbiQ-like protein/lactococcal phage abortive infection protein YP_002474862.1 249362 D 557723 CDS YP_002474863.1 219870488 7277410 249943..251685 1 NC_011852.1 involved in cytochrome bd biosynthesis, CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydD; in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 251685 cydD 7277410 cydD Haemophilus parasuis SH0165 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002474863.1 249943 D 557723 CDS YP_002474864.1 219870489 7277411 251689..253353 1 NC_011852.1 involved in cytochrome bd biosynthesis, cysteine exporter (CydDC-E) family permease/ATP-binding protein CydC; in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 253353 cydC 7277411 cydC Haemophilus parasuis SH0165 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002474864.1 251689 D 557723 CDS YP_002474865.1 219870490 7277412 complement(253476..253892) 1 NC_011852.1 COG:LR;COG0494; mutator mutT protein, NTP pyrophosphohydrolase including oxidative damage repair enzymes 253892 mutT 7277412 mutT Haemophilus parasuis SH0165 mutator mutT protein, NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_002474865.1 253476 R 557723 CDS YP_002474866.1 219870491 7277413 complement(253961..256645) 1 NC_011852.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 256645 secA 7277413 secA Haemophilus parasuis SH0165 preprotein translocase subunit SecA YP_002474866.1 253961 R 557723 CDS YP_002474867.1 219870492 7277414 complement(256733..257053) 1 NC_011852.1 hypothetical protein 257053 7277414 HAPS_0227 Haemophilus parasuis SH0165 hypothetical protein YP_002474867.1 256733 R 557723 CDS YP_002474868.1 219870493 7277415 257159..257467 1 NC_011852.1 COG:S;COG4701; hypothetical protein 257467 7277415 HAPS_0228 Haemophilus parasuis SH0165 hypothetical protein YP_002474868.1 257159 D 557723 CDS YP_002474869.1 219870494 7277416 257485..257850 1 NC_011852.1 COG:MP;COG3015; lipoprotein copper homeostasis and adhesion, NlpE 257850 nlpE 7277416 nlpE Haemophilus parasuis SH0165 lipoprotein copper homeostasis and adhesion, NlpE YP_002474869.1 257485 D 557723 CDS YP_002474870.1 219870495 7277417 complement(257942..258418) 1 NC_011852.1 COG:H;COG0801; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 258418 folK 7277417 folK Haemophilus parasuis SH0165 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002474870.1 257942 R 557723 CDS YP_002474871.1 219870496 7277418 complement(258418..259851) 1 NC_011852.1 COG:J;COG0617; polyA polymerase 259851 pcnB 7277418 pcnB Haemophilus parasuis SH0165 polyA polymerase YP_002474871.1 258418 R 557723 CDS YP_002474872.1 219870497 7277419 complement(260042..260488) 1 NC_011852.1 COG:T;COG1734; dosage-dependent DnaK suppressor protein 260488 dksA 7277419 dksA Haemophilus parasuis SH0165 dosage-dependent DnaK suppressor protein YP_002474872.1 260042 R 557723 CDS YP_002474873.1 219870498 7277420 complement(260708..262729) 1 NC_011852.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 262729 malQ 7277420 malQ Haemophilus parasuis SH0165 4-alpha-glucanotransferase YP_002474873.1 260708 R 557723 CDS YP_002474874.1 219870499 7277421 complement(262839..263729) 1 NC_011852.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 263729 malG 7277421 malG Haemophilus parasuis SH0165 maltose transporter permease YP_002474874.1 262839 R 557723 CDS YP_002474875.1 219870500 7277422 complement(263740..265296) 1 NC_011852.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 265296 malF 7277422 malF Haemophilus parasuis SH0165 maltose transporter membrane protein YP_002474875.1 263740 R 557723 CDS YP_002474876.1 219870501 7277423 complement(265545..266801) 1 NC_011852.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 266801 malE 7277423 malE Haemophilus parasuis SH0165 maltose ABC transporter periplasmic protein YP_002474876.1 265545 R 557723 CDS YP_002474877.1 219870502 7277424 267061..268200 1 NC_011852.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 268200 malK 7277424 malK Haemophilus parasuis SH0165 maltose/maltodextrin transporter ATP-binding protein YP_002474877.1 267061 D 557723 CDS YP_002474878.1 219870503 7277425 268404..269555 1 NC_011852.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 269555 hemN 7277425 hemN Haemophilus parasuis SH0165 coproporphyrinogen III oxidase YP_002474878.1 268404 D 557723 CDS YP_002474879.1 219870504 7277427 complement(269961..270884) 1 NC_011852.1 hypothetical bacteriophage protein 270884 7277427 HAPS_0240 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002474879.1 269961 R 557723 CDS YP_002474880.1 219870505 7277430 complement(271921..272088) 1 NC_011852.1 hypothetical protein 272088 7277430 HAPS_0243 Haemophilus parasuis SH0165 hypothetical protein YP_002474880.1 271921 R 557723 CDS YP_002474881.1 219870506 7277431 272745..273386 1 NC_011852.1 hypothetical protein 273386 7277431 HAPS_0244 Haemophilus parasuis SH0165 hypothetical protein YP_002474881.1 272745 D 557723 CDS YP_002474882.1 219870507 7277432 273397..273618 1 NC_011852.1 hypothetical protein 273618 7277432 HAPS_0245 Haemophilus parasuis SH0165 hypothetical protein YP_002474882.1 273397 D 557723 CDS YP_002474883.1 219870508 7277433 273683..274651 1 NC_011852.1 hypothetical protein 274651 7277433 HAPS_0246 Haemophilus parasuis SH0165 hypothetical protein YP_002474883.1 273683 D 557723 CDS YP_002474884.1 219870509 7277434 274744..275097 1 NC_011852.1 bacteriophage Mu GP27-like protein 275097 7277434 HAPS_0247 Haemophilus parasuis SH0165 bacteriophage Mu GP27-like protein YP_002474884.1 274744 D 557723 CDS YP_002474885.1 219870510 7277435 complement(275191..275655) 1 NC_011852.1 hypothetical protein 275655 7277435 HAPS_0248 Haemophilus parasuis SH0165 hypothetical protein YP_002474885.1 275191 R 557723 CDS YP_002474886.1 219870511 7277436 275756..275887 1 NC_011852.1 hypothetical protein 275887 7277436 HAPS_0249 Haemophilus parasuis SH0165 hypothetical protein YP_002474886.1 275756 D 557723 CDS YP_002474887.1 219870512 7277437 275949..276578 1 NC_011852.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 276578 lolA 7277437 lolA Haemophilus parasuis SH0165 outer-membrane lipoprotein carrier protein YP_002474887.1 275949 D 557723 CDS YP_002474888.1 219870513 7277438 276649..276960 1 NC_011852.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 276960 trpR 7277438 trpR Haemophilus parasuis SH0165 Trp operon repressor YP_002474888.1 276649 D 557723 CDS YP_002474889.1 219870514 7277439 276944..277714 1 NC_011852.1 COG:M;COG0744; monofunctional biosynthetic peptidoglycan transglycosylase 277714 mtgA 7277439 mtgA Haemophilus parasuis SH0165 monofunctional biosynthetic peptidoglycan transglycosylase YP_002474889.1 276944 D 557723 CDS YP_002474890.1 219870515 7277440 complement(277737..278474) 1 NC_011852.1 COG:P;COG0600; nitrate/sulfonate/bicarbonate ABC transporter permease 278474 7277440 HAPS_0253 Haemophilus parasuis SH0165 nitrate/sulfonate/bicarbonate ABC transporter permease YP_002474890.1 277737 R 557723 CDS YP_002474891.1 219870516 7277441 complement(278477..279643) 1 NC_011852.1 COG:P;COG0715; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein 279643 7277441 HAPS_0254 Haemophilus parasuis SH0165 nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein YP_002474891.1 278477 R 557723 CDS YP_002474892.1 219870517 7277442 complement(279652..280428) 1 NC_011852.1 COG:P;COG1116; nitrate/sulfonate/bicarbonate ABC transporter ATPase 280428 7277442 HAPS_0255 Haemophilus parasuis SH0165 nitrate/sulfonate/bicarbonate ABC transporter ATPase YP_002474892.1 279652 R 557723 CDS YP_002474893.1 219870518 7277443 280628..281695 1 NC_011852.1 COG:I;COG1960; acyl-CoA dehydrogenase 281695 7277443 HAPS_0256 Haemophilus parasuis SH0165 acyl-CoA dehydrogenase YP_002474893.1 280628 D 557723 CDS YP_002474894.1 219870519 7277444 281742..282284 1 NC_011852.1 COG:S;COG2128; putative macrophage infectivity potentiator-like protein, peroxidase/antioxidase 282284 mip 7277444 mip Haemophilus parasuis SH0165 putative macrophage infectivity potentiator-like protein, peroxidase/antioxidase YP_002474894.1 281742 D 557723 CDS YP_002474895.1 219870520 7277445 282305..283189 1 NC_011852.1 COG:HJ;COG0189; ribosomal protein S6 modification protein, glutamic acid ligase 283189 rimK 7277445 rimK Haemophilus parasuis SH0165 ribosomal protein S6 modification protein, glutamic acid ligase YP_002474895.1 282305 D 557723 CDS YP_002474896.1 219870521 7277446 283315..284646 1 NC_011852.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 284646 mukF 7277446 mukF Haemophilus parasuis SH0165 condesin subunit F YP_002474896.1 283315 D 557723 CDS YP_002474897.1 219870522 7277447 284693..285403 1 NC_011852.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 285403 mukE 7277447 mukE Haemophilus parasuis SH0165 condesin subunit E YP_002474897.1 284693 D 557723 CDS YP_002474898.1 219870523 7277448 285423..286475 1 NC_011852.1 COG:L;COG0270; Type II modification methyltransferase HpaII/DNA (cytosine-5-)-methyltransferase 286475 hpaIIM 7277448 hpaIIM Haemophilus parasuis SH0165 Type II modification methyltransferase HpaII/DNA (cytosine-5-)-methyltransferase YP_002474898.1 285423 D 557723 CDS YP_002474899.1 219870524 7277449 286483..287082 1 NC_011852.1 hypothetical protein 287082 7277449 HAPS_0262 Haemophilus parasuis SH0165 hypothetical protein YP_002474899.1 286483 D 557723 CDS YP_002474900.1 219870525 7277450 287098..291588 1 NC_011852.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 291588 mukB 7277450 mukB Haemophilus parasuis SH0165 cell division protein MukB YP_002474900.1 287098 D 557723 CDS YP_002474901.1 219870526 7277451 complement(291647..292918) 1 NC_011852.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 292918 cca 7277451 cca Haemophilus parasuis SH0165 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002474901.1 291647 R 557723 CDS YP_002474902.1 219870527 7277452 complement(292967..293635) 1 NC_011852.1 COG:C;COG0778; NAD(P)H-flavin oxidoreductase 293635 frxA 7277452 frxA Haemophilus parasuis SH0165 NAD(P)H-flavin oxidoreductase YP_002474902.1 292967 R 557723 CDS YP_002474903.1 219870528 7277453 293713..294006 1 NC_011852.1 COG:S;COG3691; tRNA-dihydrouridine synthase A 294006 dusA 7277453 dusA Haemophilus parasuis SH0165 tRNA-dihydrouridine synthase A YP_002474903.1 293713 D 557723 CDS YP_002474904.1 219870529 7277456 295171..295335 1 NC_011852.1 hypothetical protein 295335 7277456 HAPS_0267 Haemophilus parasuis SH0165 hypothetical protein YP_002474904.1 295171 D 557723 CDS YP_002474905.1 219870530 7277455 complement(295319..295849) 1 NC_011852.1 cytolethal distending toxin protein C 295849 cdtC 7277455 cdtC Haemophilus parasuis SH0165 cytolethal distending toxin protein C YP_002474905.1 295319 R 557723 CDS YP_002474906.1 219870531 7277457 complement(295860..296693) 1 NC_011852.1 cytolethal distending toxin protein B 296693 cdtB 7277457 cdtB Haemophilus parasuis SH0165 cytolethal distending toxin protein B YP_002474906.1 295860 R 557723 CDS YP_002474907.1 219870532 7277458 complement(296702..297382) 1 NC_011852.1 cytolethal distending toxin protein A 297382 cdtA 7277458 cdtA Haemophilus parasuis SH0165 cytolethal distending toxin protein A YP_002474907.1 296702 R 557723 CDS YP_002474908.1 219870533 7277459 complement(297490..299172) 1 NC_011852.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 299172 glnS 7277459 glnS Haemophilus parasuis SH0165 glutaminyl-tRNA synthetase YP_002474908.1 297490 R 557723 CDS YP_002474909.1 219870534 7277460 299369..300367 1 NC_011852.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 300367 glpX 7277460 glpX Haemophilus parasuis SH0165 fructose 1,6-bisphosphatase II YP_002474909.1 299369 D 557723 CDS YP_002474910.1 219870535 7277461 300525..302147 1 NC_011852.1 COG:L;COG0608; single-stranded-DNA-specific exonuclease RecJ 302147 recJ 7277461 recJ Haemophilus parasuis SH0165 single-stranded-DNA-specific exonuclease RecJ YP_002474910.1 300525 D 557723 CDS YP_002474911.1 219870536 7277462 302276..303121 1 NC_011852.1 COG:M;COG2885; lipoprotein Plp4/outer membrane protein and related peptidoglycan-associated (lipo)proteins 303121 plpD 7277462 plpD Haemophilus parasuis SH0165 lipoprotein Plp4/outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_002474911.1 302276 D 557723 CDS YP_002474912.1 219870537 7277463 303211..304029 1 NC_011852.1 COG:R;COG0561; cof protein, hydrolases of the HAD superfamily protein 304029 7277463 HAPS_0276 Haemophilus parasuis SH0165 cof protein, hydrolases of the HAD superfamily protein YP_002474912.1 303211 D 557723 CDS YP_002474913.1 219870538 7277464 304042..304560 1 NC_011852.1 COG:M;COG1247; sortase 304560 7277464 HAPS_0277 Haemophilus parasuis SH0165 sortase YP_002474913.1 304042 D 557723 CDS YP_002474914.1 219870539 7277465 304672..305559 1 NC_011852.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 305559 dapA 7277465 dapA Haemophilus parasuis SH0165 dihydrodipicolinate synthase YP_002474914.1 304672 D 557723 CDS YP_002474915.1 219870540 7277466 305727..307178 1 NC_011852.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 307178 lysS 7277466 lysS Haemophilus parasuis SH0165 lysyl-tRNA synthetase YP_002474915.1 305727 D 557723 CDS YP_002474916.1 219870541 7277467 307438..308211 1 NC_011852.1 COG:S;COG3022; hypothetical protein 308211 7277467 HAPS_0280 Haemophilus parasuis SH0165 hypothetical protein YP_002474916.1 307438 D 557723 CDS YP_002474917.1 219870542 7277468 308523..309248 1 NC_011852.1 COG:J;COG0052; 30S ribosomal protein S2 309248 rpsB 7277468 rpsB Haemophilus parasuis SH0165 30S ribosomal protein S2 YP_002474917.1 308523 D 557723 CDS YP_002474918.1 219870543 7277469 309343..310194 1 NC_011852.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 310194 tsf 7277469 tsf Haemophilus parasuis SH0165 elongation factor Ts YP_002474918.1 309343 D 557723 CDS YP_002474919.1 219870544 7277470 complement(310251..310967) 1 NC_011852.1 COG:C;COG1526; formate dehydrogenase accessory protein 310967 fdhD 7277470 fdhD Haemophilus parasuis SH0165 formate dehydrogenase accessory protein YP_002474919.1 310251 R 557723 CDS YP_002474920.1 219870545 7278534 311614..312201 1 NC_011852.1 COG:C;COG0243; transcriptional formate dehydrogenase alpha major subunit/formate dehydrogenase, nitrate-inducible, major subunit 312201 fdxG_2 7278534 fdxG_2 Haemophilus parasuis SH0165 transcriptional formate dehydrogenase alpha major subunit/formate dehydrogenase, nitrate-inducible, major subunit YP_002474920.1 311614 D 557723 CDS YP_002474921.1 219870546 7277267 312250..314682 1 NC_011852.1 COG:C;COG0243; transcriptional formate dehydrogenase alpha major subunit/formate dehydrogenase, nitrate-inducible, major subunit 314682 fdxG_1 7277267 fdxG_1 Haemophilus parasuis SH0165 transcriptional formate dehydrogenase alpha major subunit/formate dehydrogenase, nitrate-inducible, major subunit YP_002474921.1 312250 D 557723 CDS YP_002474922.1 219870547 7277268 314684..315610 1 NC_011852.1 COG:C;COG0437; formate dehydrogenase iron-sulfur subunit subunit beta/Fe-S-cluster-containing hydrogenase components 1 315610 fdxH 7277268 fdxH Haemophilus parasuis SH0165 formate dehydrogenase iron-sulfur subunit subunit beta/Fe-S-cluster-containing hydrogenase components 1 YP_002474922.1 314684 D 557723 CDS YP_002474923.1 219870548 7277269 315603..316271 1 NC_011852.1 COG:C;COG2864; formate dehydrogenase cytochrome B556 subunit subunit gamma 316271 fdxI 7277269 fdxI Haemophilus parasuis SH0165 formate dehydrogenase cytochrome B556 subunit subunit gamma YP_002474923.1 315603 D 557723 CDS YP_002474924.1 219870549 7277271 317398..317586 1 NC_011852.1 hypothetical protein 317586 7277271 HAPS_0289 Haemophilus parasuis SH0165 hypothetical protein YP_002474924.1 317398 D 557723 CDS YP_002474925.1 219870550 7277272 317851..320163 1 NC_011852.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 320163 glgB 7277272 glgB Haemophilus parasuis SH0165 glycogen branching protein YP_002474925.1 317851 D 557723 CDS YP_002474926.1 219870551 7277273 320433..322418 1 NC_011852.1 COG:G;COG1523; glycogen operon protein GlgX 322418 glgX 7277273 glgX Haemophilus parasuis SH0165 glycogen operon protein GlgX YP_002474926.1 320433 D 557723 CDS YP_002474927.1 219870552 7277274 322449..323738 1 NC_011852.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 323738 glgC 7277274 glgC Haemophilus parasuis SH0165 glucose-1-phosphate adenylyltransferase YP_002474927.1 322449 D 557723 CDS YP_002474928.1 219870553 7277275 323878..325311 1 NC_011852.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 325311 glgA 7277275 glgA Haemophilus parasuis SH0165 glycogen synthase YP_002474928.1 323878 D 557723 CDS YP_002474929.1 219870554 7277276 325463..326926 1 NC_011852.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 326926 guaB 7277276 guaB Haemophilus parasuis SH0165 inosine 5'-monophosphate dehydrogenase YP_002474929.1 325463 D 557723 CDS YP_002474930.1 219870555 7277277 327191..327694 1 NC_011852.1 COG:M;COG3955; exopolysaccharide biosynthesis protein 327694 7277277 HAPS_0295 Haemophilus parasuis SH0165 exopolysaccharide biosynthesis protein YP_002474930.1 327191 D 557723 CDS YP_002474931.1 219870556 7277278 327710..328390 1 NC_011852.1 putative DNA repair ATPase 328390 7277278 HAPS_0296 Haemophilus parasuis SH0165 putative DNA repair ATPase YP_002474931.1 327710 D 557723 CDS YP_002474932.1 219870557 7277279 328462..330033 1 NC_011852.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 330033 guaA 7277279 guaA Haemophilus parasuis SH0165 GMP synthase YP_002474932.1 328462 D 557723 CDS YP_002474933.1 219870558 7277282 complement(331234..331452) 1 NC_011852.1 hypothetical protein 331452 7277282 HAPS_0300 Haemophilus parasuis SH0165 hypothetical protein YP_002474933.1 331234 R 557723 CDS YP_002474934.1 219870559 7277283 complement(331901..332158) 1 NC_011852.1 COG:R;COG0727; hypothetical protein 332158 7277283 HAPS_0301 Haemophilus parasuis SH0165 hypothetical protein YP_002474934.1 331901 R 557723 CDS YP_002474935.1 219870560 7277284 complement(332155..333801) 1 NC_011852.1 DNA repair ATPase 333801 7277284 HAPS_0302 Haemophilus parasuis SH0165 DNA repair ATPase YP_002474935.1 332155 R 557723 CDS YP_002474936.1 219870561 7277285 complement(333848..334924) 1 NC_011852.1 methyl-accepting chemotaxis protein 334924 dmcA 7277285 dmcA Haemophilus parasuis SH0165 methyl-accepting chemotaxis protein YP_002474936.1 333848 R 557723 CDS YP_002474937.1 219870562 7277286 complement(334940..335326) 1 NC_011852.1 hypothetical protein 335326 7277286 HAPS_0304 Haemophilus parasuis SH0165 hypothetical protein YP_002474937.1 334940 R 557723 CDS YP_002474938.1 219870563 7277287 complement(335353..336066) 1 NC_011852.1 COG:S;COG4735; hypothetical protein 336066 7277287 HAPS_0305 Haemophilus parasuis SH0165 hypothetical protein YP_002474938.1 335353 R 557723 CDS YP_002474939.1 219870564 7277288 complement(336277..336567) 1 NC_011852.1 hypothetical protein 336567 7277288 HAPS_0306 Haemophilus parasuis SH0165 hypothetical protein YP_002474939.1 336277 R 557723 CDS YP_002474940.1 219870565 7277289 complement(336629..336967) 1 NC_011852.1 hypothetical protein 336967 7277289 HAPS_0307 Haemophilus parasuis SH0165 hypothetical protein YP_002474940.1 336629 R 557723 CDS YP_002474941.1 219870566 7277290 complement(336976..337863) 1 NC_011852.1 COG:K;COG2378; transcriptional regulator-like protein, helix-turn-helix domain-containing protein 337863 7277290 HAPS_0308 Haemophilus parasuis SH0165 transcriptional regulator-like protein, helix-turn-helix domain-containing protein YP_002474941.1 336976 R 557723 CDS YP_002474942.1 219870567 7277291 338081..338425 1 NC_011852.1 COG:K;COG1396; XRE family transcriptional regulator 338425 7277291 HAPS_0309 Haemophilus parasuis SH0165 XRE family transcriptional regulator YP_002474942.1 338081 D 557723 CDS YP_002474943.1 219870568 7277292 complement(338466..339269) 1 NC_011852.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 339269 xthA 7277292 xthA Haemophilus parasuis SH0165 exonuclease III YP_002474943.1 338466 R 557723 CDS YP_002474944.1 219870569 7277293 complement(339385..340761) 1 NC_011852.1 COG:R;COG2056; GntP family gluconate/proton (H+) symporter 340761 yojA 7277293 yojA Haemophilus parasuis SH0165 GntP family gluconate/proton (H+) symporter YP_002474944.1 339385 R 557723 CDS YP_002474945.1 219870570 7277294 complement(341069..341956) 1 NC_011852.1 COG:D;COG0037; putative ATPase 341956 mesJ 7277294 mesJ Haemophilus parasuis SH0165 putative ATPase YP_002474945.1 341069 R 557723 CDS YP_002474946.1 219870571 7277295 complement(342082..342216) 1 NC_011852.1 hypothetical protein 342216 7277295 HAPS_0314 Haemophilus parasuis SH0165 hypothetical protein YP_002474946.1 342082 R 557723 CDS YP_002474947.1 219870572 7277297 342200..342766 1 NC_011852.1 COG:H;COG0163; aromatic acid decarboxylase 342766 ubiX 7277297 ubiX Haemophilus parasuis SH0165 aromatic acid decarboxylase YP_002474947.1 342200 D 557723 CDS YP_002474948.1 219870573 7277296 complement(342801..342914) 1 NC_011852.1 hypothetical protein 342914 7277296 HAPS_0316 Haemophilus parasuis SH0165 hypothetical protein YP_002474948.1 342801 R 557723 CDS YP_002474949.1 219870574 7277299 342899..343204 1 NC_011852.1 COG:S;COG3787; hypothetical protein 343204 7277299 HAPS_0315 Haemophilus parasuis SH0165 hypothetical protein YP_002474949.1 342899 D 557723 CDS YP_002474950.1 219870575 7277298 343366..346224 1 NC_011852.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 346224 glnE 7277298 glnE Haemophilus parasuis SH0165 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002474950.1 343366 D 557723 CDS YP_002474951.1 219870576 7277300 346241..347080 1 NC_011852.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 347080 queF 7277300 queF Haemophilus parasuis SH0165 7-cyano-7-deazaguanine reductase YP_002474951.1 346241 D 557723 CDS YP_002474952.1 219870577 7277301 347193..347675 1 NC_011852.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 347675 lrp 7277301 lrp Haemophilus parasuis SH0165 leucine-responsive transcriptional regulator YP_002474952.1 347193 D 557723 CDS YP_002474953.1 219870578 7277302 347685..350288 1 NC_011852.1 COG:D;COG1674; DNA translocase FtsK involved in cell division, DNA segregation ATPase FtsK 350288 ftsK 7277302 ftsK Haemophilus parasuis SH0165 DNA translocase FtsK involved in cell division, DNA segregation ATPase FtsK YP_002474953.1 347685 D 557723 CDS YP_002474954.1 219870579 7277303 350372..351463 1 NC_011852.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 351463 aroG 7277303 aroG Haemophilus parasuis SH0165 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002474954.1 350372 D 557723 CDS YP_002474955.1 219870580 7277304 351472..352218 1 NC_011852.1 COG:O;COG1214; putative M22-like peptidase 352218 7277304 HAPS_0322 Haemophilus parasuis SH0165 putative M22-like peptidase YP_002474955.1 351472 D 557723 CDS YP_002474956.1 219870581 7277305 352226..352954 1 NC_011852.1 hypothetical protein 352954 7277305 HAPS_0323 Haemophilus parasuis SH0165 hypothetical protein YP_002474956.1 352226 D 557723 CDS YP_002474957.1 219870582 7277306 complement(353207..353737) 1 NC_011852.1 cytolethal distending toxin protein C 353737 cdtC 7277306 cdtC Haemophilus parasuis SH0165 cytolethal distending toxin protein C YP_002474957.1 353207 R 557723 CDS YP_002474958.1 219870583 7277307 complement(353748..354581) 1 NC_011852.1 cytolethal distending toxin protein B 354581 cdtB 7277307 cdtB Haemophilus parasuis SH0165 cytolethal distending toxin protein B YP_002474958.1 353748 R 557723 CDS YP_002474959.1 219870584 7277308 complement(354590..355270) 1 NC_011852.1 cytolethal distending toxin protein A 355270 cdtA 7277308 cdtA Haemophilus parasuis SH0165 cytolethal distending toxin protein A YP_002474959.1 354590 R 557723 CDS YP_002474960.1 219870585 7277309 complement(355390..356547) 1 NC_011852.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 356547 tgt 7277309 tgt Haemophilus parasuis SH0165 queuine tRNA-ribosyltransferase YP_002474960.1 355390 R 557723 CDS YP_002474961.1 219870586 7277310 complement(356627..359059) 1 NC_011852.1 COG:L;COG0187; DNA gyrase subunit B 359059 gyrB 7277310 gyrB Haemophilus parasuis SH0165 DNA gyrase subunit B YP_002474961.1 356627 R 557723 CDS YP_002474962.1 219870587 7277311 359314..359826 1 NC_011852.1 preprotein translocase subunit YajC 359826 yajC 7277311 yajC Haemophilus parasuis SH0165 preprotein translocase subunit YajC YP_002474962.1 359314 D 557723 CDS YP_002474963.1 219870588 7277312 359826..360056 1 NC_011852.1 COG:O;COG0425; SirA protein/redox protein, regulator of disulfide bond formation 360056 sirA 7277312 sirA Haemophilus parasuis SH0165 SirA protein/redox protein, regulator of disulfide bond formation YP_002474963.1 359826 D 557723 CDS YP_002474964.1 219870589 7277313 complement(360079..360423) 1 NC_011852.1 COG:S;COG3094; hypothetical protein 360423 7277313 HAPS_0331 Haemophilus parasuis SH0165 hypothetical protein YP_002474964.1 360079 R 557723 CDS YP_002474965.1 219870590 7277314 complement(360439..360972) 1 NC_011852.1 COG:S;COG3028; hypothetical protein 360972 7277314 HAPS_0332 Haemophilus parasuis SH0165 hypothetical protein YP_002474965.1 360439 R 557723 CDS YP_002474966.1 219870591 7277315 361101..362450 1 NC_011852.1 COG:R;COG0312; antibiotic maturation factor PmbA 362450 pmbA 7277315 pmbA Haemophilus parasuis SH0165 antibiotic maturation factor PmbA YP_002474966.1 361101 D 557723 CDS YP_002474967.1 219870592 7277317 complement(363517..364122) 1 NC_011852.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 364122 leuD 7277317 leuD Haemophilus parasuis SH0165 isopropylmalate isomerase small subunit YP_002474967.1 363517 R 557723 CDS YP_002474968.1 219870593 7277318 complement(364134..365540) 1 NC_011852.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 365540 leuC 7277318 leuC Haemophilus parasuis SH0165 isopropylmalate isomerase large subunit YP_002474968.1 364134 R 557723 CDS YP_002474969.1 219870594 7277319 365847..365963 1 NC_011852.1 hypothetical protein 365963 7277319 HAPS_0337 Haemophilus parasuis SH0165 hypothetical protein YP_002474969.1 365847 D 557723 CDS YP_002474970.1 219870595 7277320 complement(365957..367153) 1 NC_011852.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 367153 proP 7277320 proP Haemophilus parasuis SH0165 bicyclomycin/multidrug efflux system protein YP_002474970.1 365957 R 557723 CDS YP_002474971.1 219870596 7277321 complement(367154..367846) 1 NC_011852.1 COG:J;COG1187; ribosomal small subunit pseudouridine synthase A 367846 rsuA 7277321 rsuA Haemophilus parasuis SH0165 ribosomal small subunit pseudouridine synthase A YP_002474971.1 367154 R 557723 CDS YP_002474972.1 219870597 7277322 complement(367929..369305) 1 NC_011852.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 369305 cpxA 7277322 cpxA Haemophilus parasuis SH0165 two-component sensor protein YP_002474972.1 367929 R 557723 CDS YP_002474973.1 219870598 7277323 complement(369375..370100) 1 NC_011852.1 COG:TK;COG0745; transcriptional regulatory protein CpxR/response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 370100 cpxR 7277323 cpxR Haemophilus parasuis SH0165 transcriptional regulatory protein CpxR/response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_002474973.1 369375 R 557723 CDS YP_002474974.1 219870599 7277324 complement(370200..370976) 1 NC_011852.1 COG:R;COG1694; nucleoside triphosphate pyrophosphohydrolase 370976 mazG 7277324 mazG Haemophilus parasuis SH0165 nucleoside triphosphate pyrophosphohydrolase YP_002474974.1 370200 R 557723 CDS YP_002474975.1 219870600 7277325 371451..372776 1 NC_011852.1 COG:E;COG0006; Xaa-Pro aminopeptidase 372776 pepP 7277325 pepP Haemophilus parasuis SH0165 Xaa-Pro aminopeptidase YP_002474975.1 371451 D 557723 CDS YP_002474976.1 219870601 7277326 372840..373103 1 NC_011852.1 COG:D;COG4118; prevent-host-death family protein, antitoxin of a toxin/antitoxin system, phd-like protein 373103 phd 7277326 phd Haemophilus parasuis SH0165 prevent-host-death family protein, antitoxin of a toxin/antitoxin system, phd-like protein YP_002474976.1 372840 D 557723 CDS YP_002474977.1 219870602 7277327 373100..373507 1 NC_011852.1 unknown function but a role in signaling; COG:S;COG3744; pilT domain-containing protein 373507 pilT 7277327 pilT Haemophilus parasuis SH0165 pilT domain-containing protein YP_002474977.1 373100 D 557723 CDS YP_002474978.1 219870603 7277328 373572..374654 1 NC_011852.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 374654 serC 7277328 serC Haemophilus parasuis SH0165 phosphoserine aminotransferase YP_002474978.1 373572 D 557723 CDS YP_002474979.1 219870604 7277329 complement(374775..375746) 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 375746 7277329 HAPS_0347 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002474979.1 374775 R 557723 CDS YP_002474980.1 219870605 7277330 375987..377675 1 NC_011852.1 COG:V;COG0286; Type I restriction-modification system methyltransferase subunit 377675 hsdM 7277330 hsdM Haemophilus parasuis SH0165 Type I restriction-modification system methyltransferase subunit YP_002474980.1 375987 D 557723 CDS YP_002474981.1 219870606 7277331 377668..379032 1 NC_011852.1 COG:V;COG0732; Type I restriction-modification system, S subunit/Type I restriction modification DNA specificity domain-containing protein 379032 hsdS 7277331 hsdS Haemophilus parasuis SH0165 Type I restriction-modification system, S subunit/Type I restriction modification DNA specificity domain-containing protein YP_002474981.1 377668 D 557723 CDS YP_002474982.1 219870607 7277332 379862..383026 1 NC_011852.1 COG:V;COG0610; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases 383026 hsdR 7277332 hsdR Haemophilus parasuis SH0165 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases YP_002474982.1 379862 D 557723 CDS YP_002474983.1 219870608 7277333 383061..384155 1 NC_011852.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 384155 hisC 7277333 hisC Haemophilus parasuis SH0165 histidinol-phosphate aminotransferase YP_002474983.1 383061 D 557723 CDS YP_002474984.1 219870609 7277334 384422..384682 1 NC_011852.1 hypothetical protein 384682 7277334 HAPS_0352 Haemophilus parasuis SH0165 hypothetical protein YP_002474984.1 384422 D 557723 CDS YP_002474985.1 219870610 7277336 complement(385126..386529) 1 NC_011852.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 386529 asnC 7277336 asnC Haemophilus parasuis SH0165 asparaginyl-tRNA synthetase YP_002474985.1 385126 R 557723 CDS YP_002474986.1 219870611 7277337 complement(386743..389136) 1 NC_011852.1 COG:P;COG1629; iron-regulated outer membrane protein/TonB-dependent receptor 389136 irp 7277337 irp Haemophilus parasuis SH0165 iron-regulated outer membrane protein/TonB-dependent receptor YP_002474986.1 386743 R 557723 CDS YP_002474987.1 219870612 7277338 389322..390821 1 NC_011852.1 COG:FP;COG0248; exopolyphosphatase, Ppx/GppA phosphatase 390821 ppx 7277338 ppx Haemophilus parasuis SH0165 exopolyphosphatase, Ppx/GppA phosphatase YP_002474987.1 389322 D 557723 CDS YP_002474988.1 219870613 7277339 390982..393621 1 NC_011852.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 393621 ppc 7277339 ppc Haemophilus parasuis SH0165 phosphoenolpyruvate carboxylase YP_002474988.1 390982 D 557723 CDS YP_002474989.1 219870614 7277340 393869..395026 1 NC_011852.1 COG:E;COG0128; 3-phosphoshikimate 1-carboxyvinyltransferase 395026 aroA 7277340 aroA Haemophilus parasuis SH0165 3-phosphoshikimate 1-carboxyvinyltransferase YP_002474989.1 393869 D 557723 CDS YP_002474990.1 219870615 7277341 complement(395181..395390) 1 NC_011852.1 COG:K;COG1278; cold shock-like protein CspD 395390 cspD 7277341 cspD Haemophilus parasuis SH0165 cold shock-like protein CspD YP_002474990.1 395181 R 557723 CDS YP_002474991.1 219870616 7277342 395596..396075 1 NC_011852.1 COG:O;COG1225; thioredoxin-dependent thiol peroxidase 396075 bcp 7277342 bcp Haemophilus parasuis SH0165 thioredoxin-dependent thiol peroxidase YP_002474991.1 395596 D 557723 CDS YP_002474992.1 219870617 7277343 396065..396634 1 NC_011852.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 396634 gmhB 7277343 gmhB Haemophilus parasuis SH0165 D,D-heptose 1,7-bisphosphate phosphatase YP_002474992.1 396065 D 557723 CDS YP_002474993.1 219870618 7277344 396768..397307 1 NC_011852.1 COG:F;COG0634; hypoxanthine-guanine phosphoribosyltransferase 397307 hpt 7277344 hpt Haemophilus parasuis SH0165 hypoxanthine-guanine phosphoribosyltransferase YP_002474993.1 396768 D 557723 CDS YP_002474994.1 219870619 7277345 397400..399475 1 NC_011852.1 COG:M;COG0741; putative soluble lytic murein transglycosylase 399475 slt 7277345 slt Haemophilus parasuis SH0165 putative soluble lytic murein transglycosylase YP_002474994.1 397400 D 557723 CDS YP_002474995.1 219870620 7277346 399565..400107 1 NC_011852.1 ATPases of ABC transporters with duplicated ATPase domains-containing protein 400107 7277346 HAPS_0364 Haemophilus parasuis SH0165 ATPases of ABC transporters with duplicated ATPase domains-containing protein YP_002474995.1 399565 D 557723 CDS YP_002474996.1 219870621 7277347 400107..400994 1 NC_011852.1 COG:P;COG0053; cation-efflux pump FieF Co/Zn/Cd cation transporter 400994 fieF 7277347 fieF Haemophilus parasuis SH0165 cation-efflux pump FieF Co/Zn/Cd cation transporter YP_002474996.1 400107 D 557723 CDS YP_002474997.1 219870622 7276925 complement(401166..402152) 1 NC_011852.1 COG:L;COG3547; ISCro4, family IS110 402152 7276925 HAPS_0366 Haemophilus parasuis SH0165 ISCro4, family IS110 YP_002474997.1 401166 R 557723 CDS YP_002474998.1 219870623 7276926 402604..403590 1 NC_011852.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 403590 menC 7276926 menC Haemophilus parasuis SH0165 O-succinylbenzoate synthase YP_002474998.1 402604 D 557723 CDS YP_002474999.1 219870624 7276929 complement(408169..408552) 1 NC_011852.1 COG:S;COG3112; hypothetical protein 408552 7276929 HAPS_0370 Haemophilus parasuis SH0165 hypothetical protein YP_002474999.1 408169 R 557723 CDS YP_002475000.1 219870625 7276930 complement(408637..411465) 1 NC_011852.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 411465 uvrA 7276930 uvrA Haemophilus parasuis SH0165 excinuclease ABC subunit A YP_002475000.1 408637 R 557723 CDS YP_002475001.1 219870626 7276931 411724..412242 1 NC_011852.1 COG:L;COG0629; single-strand DNA-binding protein 412242 ssb 7276931 ssb Haemophilus parasuis SH0165 single-strand DNA-binding protein YP_002475001.1 411724 D 557723 CDS YP_002475002.1 219870627 7276932 412450..413664 1 NC_011852.1 COG:R;COG1373; ATPase ATPase (AAA+ superfamily) 413664 7276932 HAPS_0373 Haemophilus parasuis SH0165 ATPase ATPase (AAA+ superfamily) YP_002475002.1 412450 D 557723 CDS YP_002475003.1 219870628 7276934 complement(414054..415274) 1 NC_011852.1 COG:LKJ;COG0513; ATP-dependent RNA helicase RhlB 415274 rhlB 7276934 rhlB Haemophilus parasuis SH0165 ATP-dependent RNA helicase RhlB YP_002475003.1 414054 R 557723 CDS YP_002475004.1 219870629 7276935 complement(415338..415610) 1 NC_011852.1 COG:R;COG3093; plasmid maintenance system antidote protein, XRE family/addiction module antidote protein, HigA family/PSEEN1946 proteic killer active protein 415610 higA 7276935 higA Haemophilus parasuis SH0165 plasmid maintenance system antidote protein, XRE family/addiction module antidote protein, HigA family/PSEEN1946 proteic killer active protein YP_002475004.1 415338 R 557723 CDS YP_002475005.1 219870630 7276936 complement(415621..415899) 1 NC_011852.1 COG:R;COG3549; plasmid maintenance system killer/proteic killer protein, RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system 415899 higB 7276936 higB Haemophilus parasuis SH0165 plasmid maintenance system killer/proteic killer protein, RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system YP_002475005.1 415621 R 557723 CDS YP_002475006.1 219870631 7276937 416048..417058 1 NC_011852.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 417058 arg 7276937 arg Haemophilus parasuis SH0165 ornithine carbamoyltransferase YP_002475006.1 416048 D 557723 CDS YP_002475007.1 219870632 7276938 417405..418667 1 NC_011852.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 418667 glyA 7276938 glyA Haemophilus parasuis SH0165 serine hydroxymethyltransferase YP_002475007.1 417405 D 557723 CDS YP_002475008.1 219870633 7276939 418781..420109 1 NC_011852.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 420109 xseA 7276939 xseA Haemophilus parasuis SH0165 exodeoxyribonuclease VII large subunit YP_002475008.1 418781 D 557723 CDS YP_002475009.1 219870634 7276940 complement(420143..422350) 1 NC_011852.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 422350 parC 7276940 parC Haemophilus parasuis SH0165 DNA topoisomerase IV subunit A YP_002475009.1 420143 R 557723 CDS YP_002475010.1 219870635 7276941 422482..422847 1 NC_011852.1 hypothetical protein 422847 7276941 HAPS_0382 Haemophilus parasuis SH0165 hypothetical protein YP_002475010.1 422482 D 557723 CDS YP_002475011.1 219870636 7276942 complement(423000..423782) 1 NC_011852.1 COG:R;COG0596; putative esterase 423782 mhpC 7276942 mhpC Haemophilus parasuis SH0165 putative esterase YP_002475011.1 423000 R 557723 CDS YP_002475012.1 219870637 7276943 423890..424450 1 NC_011852.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 424450 seqA 7276943 seqA Haemophilus parasuis SH0165 replication initiation regulator SeqA YP_002475012.1 423890 D 557723 CDS YP_002475013.1 219870638 7276944 424454..425869 1 NC_011852.1 COG:IQ;COG0318; O-succinylbenzoic acid--CoA ligase 425869 menE 7276944 menE Haemophilus parasuis SH0165 O-succinylbenzoic acid--CoA ligase YP_002475013.1 424454 D 557723 CDS YP_002475014.1 219870639 7276945 425862..429155 1 NC_011852.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 429155 kefA 7276945 kefA Haemophilus parasuis SH0165 potassium efflux protein KefA YP_002475014.1 425862 D 557723 CDS YP_002475015.1 219870640 7276946 429281..430363 1 NC_011852.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 430363 aroC 7276946 aroC Haemophilus parasuis SH0165 chorismate synthase YP_002475015.1 429281 D 557723 CDS YP_002475016.1 219870641 7276947 430571..430846 1 NC_011852.1 COG:R;COG3549; plasmid maintenance system killer/proteic killer protein, RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system 430846 higB 7276947 higB Haemophilus parasuis SH0165 plasmid maintenance system killer/proteic killer protein, RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system YP_002475016.1 430571 D 557723 CDS YP_002475017.1 219870642 7276948 430855..431151 1 NC_011852.1 COG:R;COG3093; plasmid maintenance system antidote protein, XRE family/addiction module antidote protein, HigA family/PSEEN1946 proteic killer active protein 431151 higA 7276948 higA Haemophilus parasuis SH0165 plasmid maintenance system antidote protein, XRE family/addiction module antidote protein, HigA family/PSEEN1946 proteic killer active protein YP_002475017.1 430855 D 557723 CDS YP_002475018.1 219870643 7276949 complement(431167..432372) 1 NC_011852.1 COG:KG;COG1940; transcriptional repressor of carbohydrate metabolism; PTS operon /sugar kinase 432372 mlc 7276949 mlc Haemophilus parasuis SH0165 transcriptional repressor of carbohydrate metabolism; PTS operon /sugar kinase YP_002475018.1 431167 R 557723 CDS YP_002475019.1 219870644 7276950 432547..433674 1 NC_011852.1 COG:J;COG0349; ribonuclease D 433674 rnd 7276950 rnd Haemophilus parasuis SH0165 ribonuclease D YP_002475019.1 432547 D 557723 CDS YP_002475020.1 219870645 7276951 434123..435322 1 NC_011852.1 COG:C;COG0282; acetate kinase 435322 ackA 7276951 ackA Haemophilus parasuis SH0165 acetate kinase YP_002475020.1 434123 D 557723 CDS YP_002475021.1 219870646 7276952 complement(435288..435443) 1 NC_011852.1 hypothetical protein 435443 7276952 HAPS_0394 Haemophilus parasuis SH0165 hypothetical protein YP_002475021.1 435288 R 557723 CDS YP_002475022.1 219870647 7276954 435431..437566 1 NC_011852.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 437566 pta 7276954 pta Haemophilus parasuis SH0165 phosphate acetyltransferase YP_002475022.1 435431 D 557723 CDS YP_002475023.1 219870648 7276953 complement(437677..438636) 1 NC_011852.1 COG:R;COG2984; ABC transporter substrate-binding protein 438636 7276953 HAPS_0395 Haemophilus parasuis SH0165 ABC transporter substrate-binding protein YP_002475023.1 437677 R 557723 CDS YP_002475024.1 219870649 7276955 complement(438815..439222) 1 NC_011852.1 COG:R;COG2969; ClpXP protease specificity-enhancing factor 439222 sspB 7276955 sspB Haemophilus parasuis SH0165 ClpXP protease specificity-enhancing factor YP_002475024.1 438815 R 557723 CDS YP_002475025.1 219870650 7276956 complement(439224..439865) 1 NC_011852.1 COG:O;COG0625; stringent starvation protein A/glutathione S-transferase 439865 sspA 7276956 sspA Haemophilus parasuis SH0165 stringent starvation protein A/glutathione S-transferase YP_002475025.1 439224 R 557723 CDS YP_002475026.1 219870651 7276957 440081..440398 1 NC_011852.1 COG:S;COG2926; hypothetical protein 440398 7276957 HAPS_0398 Haemophilus parasuis SH0165 hypothetical protein YP_002475026.1 440081 D 557723 CDS YP_002475027.1 219870652 7276958 complement(440442..441740) 1 NC_011852.1 COG:H;COG0285; folylpolyglutamate synthase 441740 folC 7276958 folC Haemophilus parasuis SH0165 folylpolyglutamate synthase YP_002475027.1 440442 R 557723 CDS YP_002475028.1 219870653 7276959 complement(441740..442630) 1 NC_011852.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 442630 accD 7276959 accD Haemophilus parasuis SH0165 acetyl-CoA carboxylase subunit beta YP_002475028.1 441740 R 557723 CDS YP_002475029.1 219870654 7276960 complement(442718..443074) 1 NC_011852.1 COG:T;COG2337; growth inhibitor, PemK-like, autoregulated/transcriptional modulator of MazE/toxin, MazF, plasmid stable inheritance protein K 443074 chpA 7276960 chpA Haemophilus parasuis SH0165 growth inhibitor, PemK-like, autoregulated/transcriptional modulator of MazE/toxin, MazF, plasmid stable inheritance protein K YP_002475029.1 442718 R 557723 CDS YP_002475030.1 219870655 7276961 complement(443074..443343) 1 NC_011852.1 COG:T;COG2336; antitoxin ChpS/ transcriptional regulator/antitoxin 443343 chpS 7276961 chpS Haemophilus parasuis SH0165 antitoxin ChpS/ transcriptional regulator/antitoxin YP_002475030.1 443074 R 557723 CDS YP_002475031.1 219870656 7276962 443594..444784 1 NC_011852.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 444784 aspC 7276962 aspC Haemophilus parasuis SH0165 aromatic amino acid aminotransferase YP_002475031.1 443594 D 557723 CDS YP_002475032.1 219870657 7276963 complement(444865..445779) 1 NC_011852.1 COG:GER;COG0697; drug/metabolite exporter family transporter 445779 7276963 HAPS_0404 Haemophilus parasuis SH0165 drug/metabolite exporter family transporter YP_002475032.1 444865 R 557723 CDS YP_002475033.1 219870658 7276964 445980..447038 1 NC_011852.1 COG:R;COG2081; flavoprotein 447038 7276964 HAPS_0405 Haemophilus parasuis SH0165 flavoprotein YP_002475033.1 445980 D 557723 CDS YP_002475034.1 219870659 7276965 complement(447102..447983) 1 NC_011852.1 COG:EM;COG0329; N-acetylneuraminate lyase 447983 nanA 7276965 nanA Haemophilus parasuis SH0165 N-acetylneuraminate lyase YP_002475034.1 447102 R 557723 CDS YP_002475035.1 219870660 7276966 complement(448065..448931) 1 NC_011852.1 COG:K;COG1737; putative HTH-type transcriptional regulator 448931 7276966 HAPS_0407 Haemophilus parasuis SH0165 putative HTH-type transcriptional regulator YP_002475035.1 448065 R 557723 CDS YP_002475036.1 219870661 7276967 complement(448933..449403) 1 NC_011852.1 COG:G;COG2731; hypothetical protein 449403 7276967 HAPS_0408 Haemophilus parasuis SH0165 hypothetical protein YP_002475036.1 448933 R 557723 CDS YP_002475037.1 219870662 7276969 450581..450859 1 NC_011852.1 COG:R;COG3549; plasmid maintenance system killer/proteic killer protein, RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system 450859 higB 7276969 higB Haemophilus parasuis SH0165 plasmid maintenance system killer/proteic killer protein, RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system YP_002475037.1 450581 D 557723 CDS YP_002475038.1 219870663 7276970 450871..451152 1 NC_011852.1 COG:R;COG3093; plasmid maintenance system antidote protein, XRE family/addiction module antidote protein, HigA family/PSEEN1946 proteic killer active protein 451152 higA 7276970 higA Haemophilus parasuis SH0165 plasmid maintenance system antidote protein, XRE family/addiction module antidote protein, HigA family/PSEEN1946 proteic killer active protein YP_002475038.1 450871 D 557723 CDS YP_002475039.1 219870664 7276971 complement(451149..451886) 1 NC_011852.1 COG:S;COG4672; phage-like minor tail protein L 451886 7276971 HAPS_0412 Haemophilus parasuis SH0165 phage-like minor tail protein L YP_002475039.1 451149 R 557723 CDS YP_002475040.1 219870665 7276974 complement(453224..454711) 1 NC_011852.1 chromosome segregation ATPase 454711 7276974 HAPS_0415 Haemophilus parasuis SH0165 chromosome segregation ATPase YP_002475040.1 453224 R 557723 CDS YP_002475041.1 219870666 7276975 complement(454829..455176) 1 NC_011852.1 putative phage-like lipoprotein 455176 7276975 HAPS_0416 Haemophilus parasuis SH0165 putative phage-like lipoprotein YP_002475041.1 454829 R 557723 CDS YP_002475042.1 219870667 7276976 complement(455253..455579) 1 NC_011852.1 COG:S;COG4718; phage minor tail protein 455579 7276976 HAPS_0417 Haemophilus parasuis SH0165 phage minor tail protein YP_002475042.1 455253 R 557723 CDS YP_002475043.1 219870668 7276977 complement(455581..455916) 1 NC_011852.1 hypothetical protein 455916 7276977 HAPS_0418 Haemophilus parasuis SH0165 hypothetical protein YP_002475043.1 455581 R 557723 CDS YP_002475044.1 219870669 7276978 complement(455925..456845) 1 NC_011852.1 hypothetical protein 456845 7276978 HAPS_0419 Haemophilus parasuis SH0165 hypothetical protein YP_002475044.1 455925 R 557723 CDS YP_002475045.1 219870670 7276982 complement(459049..459174) 1 NC_011852.1 hypothetical protein 459174 7276982 HAPS_0423 Haemophilus parasuis SH0165 hypothetical protein YP_002475045.1 459049 R 557723 CDS YP_002475046.1 219870671 7276986 complement(461000..461329) 1 NC_011852.1 COG:U;COG1314; preprotein translocase subunit SecG 461329 secG 7276986 secG Haemophilus parasuis SH0165 preprotein translocase subunit SecG YP_002475046.1 461000 R 557723 CDS YP_002475047.1 219870672 7276987 complement(461455..463377) 1 NC_011852.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 463377 topB 7276987 topB Haemophilus parasuis SH0165 DNA topoisomerase III YP_002475047.1 461455 R 557723 CDS YP_002475048.1 219870673 7276988 complement(463385..464209) 1 NC_011852.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 464209 mepA 7276988 mepA Haemophilus parasuis SH0165 penicillin-insensitive murein endopeptidase YP_002475048.1 463385 R 557723 CDS YP_002475049.1 219870674 7276990 complement(464567..464965) 1 NC_011852.1 COG:S;COG2363; CTP synthetase, potential integral membrane protein 464965 pyrG 7276990 pyrG Haemophilus parasuis SH0165 CTP synthetase, potential integral membrane protein YP_002475049.1 464567 R 557723 CDS YP_002475050.1 219870675 7276992 complement(465228..465590) 1 NC_011852.1 COG:K;COG5499; putative transcription regulator containing HTH domain 465590 7276992 HAPS_0433 Haemophilus parasuis SH0165 putative transcription regulator containing HTH domain YP_002475050.1 465228 R 557723 CDS YP_002475051.1 219870676 7276993 complement(465600..465902) 1 NC_011852.1 COG:S;COG4680; hypothetical protein 465902 7276993 HAPS_0434 Haemophilus parasuis SH0165 hypothetical protein YP_002475051.1 465600 R 557723 CDS YP_002475052.1 219870677 7276994 complement(465922..466041) 1 NC_011852.1 hypothetical protein 466041 7276994 HAPS_0435 Haemophilus parasuis SH0165 hypothetical protein YP_002475052.1 465922 R 557723 CDS YP_002475053.1 219870678 7276995 466329..467348 1 NC_011852.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 467348 moaA 7276995 moaA Haemophilus parasuis SH0165 molybdenum cofactor biosynthesis protein A YP_002475053.1 466329 D 557723 CDS YP_002475054.1 219870679 7276996 467502..467981 1 NC_011852.1 COG:H;COG0315; molybdenum cofactor biosynthesis protein C 467981 moaC 7276996 moaC Haemophilus parasuis SH0165 molybdenum cofactor biosynthesis protein C YP_002475054.1 467502 D 557723 CDS YP_002475055.1 219870680 7276997 468066..468311 1 NC_011852.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 468311 moaD 7276997 moaD Haemophilus parasuis SH0165 molybdopterin synthase small subunit YP_002475055.1 468066 D 557723 CDS YP_002475056.1 219870681 7276998 468312..468764 1 NC_011852.1 COG:H;COG0314; molybdopterin converting factor, large subunit 468764 moaE 7276998 moaE Haemophilus parasuis SH0165 molybdopterin converting factor, large subunit YP_002475056.1 468312 D 557723 CDS YP_002475057.1 219870682 7276999 468796..469284 1 NC_011852.1 COG:R;COG0319; putative metalloprotease 469284 7276999 HAPS_0440 Haemophilus parasuis SH0165 putative metalloprotease YP_002475057.1 468796 D 557723 CDS YP_002475058.1 219870683 7277000 469284..471134 1 NC_011852.1 COG:R;COG1444; acetyltransferase 471134 7277000 HAPS_0441 Haemophilus parasuis SH0165 acetyltransferase YP_002475058.1 469284 D 557723 CDS YP_002475059.1 219870684 7277001 471259..472251 1 NC_011852.1 COG:G;COG1879; galactose ABC transporter periplasmic-binding protein/LacI transcriptional regulator 472251 mglB 7277001 mglB Haemophilus parasuis SH0165 galactose ABC transporter periplasmic-binding protein/LacI transcriptional regulator YP_002475059.1 471259 D 557723 CDS YP_002475060.1 219870685 7277002 472304..473824 1 NC_011852.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 473824 mglA 7277002 mglA Haemophilus parasuis SH0165 galactose/methyl galaxtoside transporter ATP-binding protein YP_002475060.1 472304 D 557723 CDS YP_002475061.1 219870686 7277003 473841..474851 1 NC_011852.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 474851 mglC 7277003 mglC Haemophilus parasuis SH0165 beta-methylgalactoside transporter inner membrane protein YP_002475061.1 473841 D 557723 CDS YP_002475062.1 219870687 7277004 complement(475028..475819) 1 NC_011852.1 COG:P;COG1464; DL-methionine transporter substrate-binding subunit/outer membrane lipoprotein 3 (PLP3) 475819 metQ 7277004 metQ Haemophilus parasuis SH0165 DL-methionine transporter substrate-binding subunit/outer membrane lipoprotein 3 (PLP3) YP_002475062.1 475028 R 557723 CDS YP_002475063.1 219870688 7277005 complement(475891..476730) 1 NC_011852.1 COG:P;COG1464; metal ion ABC transporter periplasmic component/outer membrane lipoprotein 1 476730 plpA 7277005 plpA Haemophilus parasuis SH0165 metal ion ABC transporter periplasmic component/outer membrane lipoprotein 1 YP_002475063.1 475891 R 557723 CDS YP_002475064.1 219870689 7278452 complement(476763..477440) 1 NC_011852.1 COG:P;COG2011; D-methionine transport system permease protein MetI 477440 metI 7278452 metI Haemophilus parasuis SH0165 D-methionine transport system permease protein MetI YP_002475064.1 476763 R 557723 CDS YP_002475065.1 219870690 7278453 complement(477430..478464) 1 NC_011852.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 478464 metN 7278453 metN Haemophilus parasuis SH0165 DL-methionine transporter ATP-binding subunit YP_002475065.1 477430 R 557723 CDS YP_002475066.1 219870691 7278454 478741..479394 1 NC_011852.1 COG:U;COG2095; hypothetical protein 479394 marC 7278454 marC Haemophilus parasuis SH0165 hypothetical protein YP_002475066.1 478741 D 557723 CDS YP_002475067.1 219870692 7278455 479396..480937 1 NC_011852.1 COG:E;COG4166; putative oligopeptide transporter, periplasmic-binding protein, OppA 480937 oppA 7278455 oppA Haemophilus parasuis SH0165 putative oligopeptide transporter, periplasmic-binding protein, OppA YP_002475067.1 479396 D 557723 CDS YP_002475068.1 219870693 7278456 480938..482035 1 NC_011852.1 COG:D;COG0489; putative ATPase 482035 mrp 7278456 mrp Haemophilus parasuis SH0165 putative ATPase YP_002475068.1 480938 D 557723 CDS YP_002475069.1 219870694 7278458 486714..487856 1 NC_011852.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 487856 argE 7278458 argE Haemophilus parasuis SH0165 acetylornithine deacetylase YP_002475069.1 486714 D 557723 CDS YP_002475070.1 219870695 7278459 complement(488005..488748) 1 NC_011852.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 488748 moeB 7278459 moeB Haemophilus parasuis SH0165 molybdopterin biosynthesis protein MoeB YP_002475070.1 488005 R 557723 CDS YP_002475071.1 219870696 7278460 complement(488751..489050) 1 NC_011852.1 COG:J;COG0023; translation initiation factor Sui1, translation initiation factor 1 (eIF-1/SUI1) 489050 yciH 7278460 yciH Haemophilus parasuis SH0165 translation initiation factor Sui1, translation initiation factor 1 (eIF-1/SUI1) YP_002475071.1 488751 R 557723 CDS YP_002475072.1 219870697 7278461 complement(489082..489774) 1 NC_011852.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 489774 pyrF 7278461 pyrF Haemophilus parasuis SH0165 orotidine 5'-phosphate decarboxylase YP_002475072.1 489082 R 557723 CDS YP_002475073.1 219870698 7278462 complement(489790..490983) 1 NC_011852.1 COG:G;COG2956; tetratricopeptide repeat protein 490983 7278462 HAPS_0457 Haemophilus parasuis SH0165 tetratricopeptide repeat protein YP_002475073.1 489790 R 557723 CDS YP_002475074.1 219870699 7278463 complement(490983..491267) 1 NC_011852.1 COG:S;COG3771; hypothetical protein 491267 7278463 HAPS_0458 Haemophilus parasuis SH0165 hypothetical protein YP_002475074.1 490983 R 557723 CDS YP_002475075.1 219870700 7278464 complement(491336..491617) 1 NC_011852.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 491617 ihfB 7278464 ihfB Haemophilus parasuis SH0165 integration host factor subunit beta YP_002475075.1 491336 R 557723 CDS YP_002475076.1 219870701 7278465 complement(491683..493350) 1 NC_011852.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 493350 rpsA 7278465 rpsA Haemophilus parasuis SH0165 30S ribosomal protein S1 YP_002475076.1 491683 R 557723 CDS YP_002475077.1 219870702 7278466 complement(493447..494112) 1 NC_011852.1 COG:F;COG0283; cytidylate kinase 494112 cmk 7278466 cmk Haemophilus parasuis SH0165 cytidylate kinase YP_002475077.1 493447 R 557723 CDS YP_002475078.1 219870703 7278467 complement(494122..495150) 1 NC_011852.1 COG:O;COG0265; protease DegS 495150 degS 7278467 degS Haemophilus parasuis SH0165 protease DegS YP_002475078.1 494122 R 557723 CDS YP_002475079.1 219870704 7278468 complement(495260..496147) 1 NC_011852.1 COG:M;COG1210; UTP-glucose-1-phosphate uridylyltransferase 496147 galU 7278468 galU Haemophilus parasuis SH0165 UTP-glucose-1-phosphate uridylyltransferase YP_002475079.1 495260 R 557723 CDS YP_002475080.1 219870705 7278469 complement(496327..496512) 1 NC_011852.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 496512 csrA 7278469 csrA Haemophilus parasuis SH0165 carbon storage regulator YP_002475080.1 496327 R 557723 CDS YP_002475081.1 219870706 7278470 complement(496576..499203) 1 NC_011852.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 499203 alaS 7278470 alaS Haemophilus parasuis SH0165 alanyl-tRNA synthetase YP_002475081.1 496576 R 557723 CDS YP_002475082.1 219870707 7278471 complement(499428..499853) 1 NC_011852.1 COG:T;COG0589; universal stress protein A 499853 uspA 7278471 uspA Haemophilus parasuis SH0165 universal stress protein A YP_002475082.1 499428 R 557723 CDS YP_002475083.1 219870708 7278472 500165..502444 1 NC_011852.1 COG:R;COG0658; recombination protein 2 502444 rec2 7278472 rec2 Haemophilus parasuis SH0165 recombination protein 2 YP_002475083.1 500165 D 557723 CDS YP_002475084.1 219870709 7278473 complement(502612..502908) 1 NC_011852.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 502908 yciI 7278473 yciI Haemophilus parasuis SH0165 YciI-like protein YP_002475084.1 502612 R 557723 CDS YP_002475085.1 219870710 7278474 complement(502920..503360) 1 NC_011852.1 COG:I;COG1607; putative acyl-CoA thioester hydrolase 503360 7278474 HAPS_0469 Haemophilus parasuis SH0165 putative acyl-CoA thioester hydrolase YP_002475085.1 502920 R 557723 CDS YP_002475086.1 219870711 7278475 complement(503344..503907) 1 NC_011852.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 503907 ispZ 7278475 ispZ Haemophilus parasuis SH0165 intracellular septation protein A YP_002475086.1 503344 R 557723 CDS YP_002475087.1 219870712 7278476 complement(503916..504644) 1 NC_011852.1 hypothetical protein 504644 7278476 HAPS_0471 Haemophilus parasuis SH0165 hypothetical protein YP_002475087.1 503916 R 557723 CDS YP_002475088.1 219870713 7278477 504823..505257 1 NC_011852.1 COG:S;COG3092; membrane protein 505257 7278477 HAPS_0472 Haemophilus parasuis SH0165 membrane protein YP_002475088.1 504823 D 557723 CDS YP_002475089.1 219870714 7278478 complement(505239..505712) 1 NC_011852.1 COG:FJ;COG0590; tRNA-adenosine deaminase 505712 tadA 7278478 tadA Haemophilus parasuis SH0165 tRNA-adenosine deaminase YP_002475089.1 505239 R 557723 CDS YP_002475090.1 219870715 7278479 complement(505873..507684) 1 NC_011852.1 COG:LKJ;COG0513; cold-shock DEAD box protein A-like protein 507684 deaD 7278479 deaD Haemophilus parasuis SH0165 cold-shock DEAD box protein A-like protein YP_002475090.1 505873 R 557723 CDS YP_002475091.1 219870716 7278480 complement(507956..508882) 1 NC_011852.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 508882 nlpI 7278480 nlpI Haemophilus parasuis SH0165 lipoprotein NlpI YP_002475091.1 507956 R 557723 CDS YP_002475092.1 219870717 7278481 complement(508956..511085) 1 NC_011852.1 COG:J;COG1185; polynucleotide phosphorylase/polyadenylase 511085 pnp 7278481 pnp Haemophilus parasuis SH0165 polynucleotide phosphorylase/polyadenylase YP_002475092.1 508956 R 557723 CDS YP_002475093.1 219870718 7278483 complement(513446..515092) 1 NC_011852.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 515092 ushA 7278483 ushA Haemophilus parasuis SH0165 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_002475093.1 513446 R 557723 CDS YP_002475094.1 219870719 7278484 complement(515139..515501) 1 NC_011852.1 COG:M;COG0818; diacylglycerol kinase 515501 dgkA 7278484 dgkA Haemophilus parasuis SH0165 diacylglycerol kinase YP_002475094.1 515139 R 557723 CDS YP_002475095.1 219870720 7278485 complement(515659..517893) 1 NC_011852.1 COG:T;COG0642; aerobic respiration control sensor protein ArcB 517893 arcB 7278485 arcB Haemophilus parasuis SH0165 aerobic respiration control sensor protein ArcB YP_002475095.1 515659 R 557723 CDS YP_002475096.1 219870721 7278486 complement(517979..520231) 1 NC_011852.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 520231 ostA 7278486 ostA Haemophilus parasuis SH0165 organic solvent tolerance protein YP_002475096.1 517979 R 557723 CDS YP_002475097.1 219870722 7278487 complement(520380..521747) 1 NC_011852.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 521747 hemN 7278487 hemN Haemophilus parasuis SH0165 coproporphyrinogen III oxidase YP_002475097.1 520380 R 557723 CDS YP_002475098.1 219870723 7278488 complement(521750..522196) 1 NC_011852.1 ATP-dependent Lon protease 522196 7278488 HAPS_0483 Haemophilus parasuis SH0165 ATP-dependent Lon protease YP_002475098.1 521750 R 557723 CDS YP_002475099.1 219870724 7278489 complement(522205..522738) 1 NC_011852.1 COG:S;COG3078; hypothetical protein 522738 7278489 HAPS_0484 Haemophilus parasuis SH0165 hypothetical protein YP_002475099.1 522205 R 557723 CDS YP_002475100.1 219870725 7278490 complement(522875..523582) 1 NC_011852.1 COG:S;COG2949; SanA protein, membrane protein 523582 sanA 7278490 sanA Haemophilus parasuis SH0165 SanA protein, membrane protein YP_002475100.1 522875 R 557723 CDS YP_002475101.1 219870726 7278491 complement(523586..524479) 1 NC_011852.1 COG:GER;COG0697; transporter, drug/metabolite exporter family 524479 7278491 HAPS_0486 Haemophilus parasuis SH0165 transporter, drug/metabolite exporter family YP_002475101.1 523586 R 557723 CDS YP_002475102.1 219870727 7278494 complement(525459..527768) 1 NC_011852.1 COG:K;COG2183; transcriptional accessory protein (S1 RNA binding domain) 527768 7278494 HAPS_0489 Haemophilus parasuis SH0165 transcriptional accessory protein (S1 RNA binding domain) YP_002475102.1 525459 R 557723 CDS YP_002475103.1 219870728 7278495 complement(527899..529323) 1 NC_011852.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 529323 lpdA 7278495 lpdA Haemophilus parasuis SH0165 dihydrolipoamide dehydrogenase YP_002475103.1 527899 R 557723 CDS YP_002475104.1 219870729 7278496 complement(529440..531065) 1 NC_011852.1 COG:C;COG0508; dihydrolipoamide acetyltransferase 531065 aceF 7278496 aceF Haemophilus parasuis SH0165 dihydrolipoamide acetyltransferase YP_002475104.1 529440 R 557723 CDS YP_002475105.1 219870730 7278497 complement(531120..533777) 1 NC_011852.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 533777 aceE 7278497 aceE Haemophilus parasuis SH0165 pyruvate dehydrogenase subunit E1 YP_002475105.1 531120 R 557723 CDS YP_002475106.1 219870731 7278498 complement(533880..534038) 1 NC_011852.1 hypothetical protein 534038 7278498 HAPS_0493 Haemophilus parasuis SH0165 hypothetical protein YP_002475106.1 533880 R 557723 CDS YP_002475107.1 219870732 7278499 534159..534653 1 NC_011852.1 COG:F;COG0041; phosphoribosylaminoimidazole carboxylasecatalytic subunit 534653 purE 7278499 purE Haemophilus parasuis SH0165 phosphoribosylaminoimidazole carboxylasecatalytic subunit YP_002475107.1 534159 D 557723 CDS YP_002475108.1 219870733 7278500 534699..535619 1 NC_011852.1 COG:EJ;COG0252; L-asparaginase 535619 ansB 7278500 ansB Haemophilus parasuis SH0165 L-asparaginase YP_002475108.1 534699 D 557723 CDS YP_002475109.1 219870734 7278501 535739..536833 1 NC_011852.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 536833 purK 7278501 purK Haemophilus parasuis SH0165 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002475109.1 535739 D 557723 CDS YP_002475110.1 219870735 7278502 536927..537436 1 NC_011852.1 COG:O;COG0652; peptidyl-prolyl isomerase 537436 ppiB 7278502 ppiB Haemophilus parasuis SH0165 peptidyl-prolyl isomerase YP_002475110.1 536927 D 557723 CDS YP_002475111.1 219870736 7278503 537504..538214 1 NC_011852.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 538214 ubiG 7278503 ubiG Haemophilus parasuis SH0165 3-demethylubiquinone-9 3-methyltransferase YP_002475111.1 537504 D 557723 CDS YP_002475112.1 219870737 7278505 complement(543374..544522) 1 NC_011852.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 544522 metK 7278505 metK Haemophilus parasuis SH0165 S-adenosylmethionine synthetase YP_002475112.1 543374 R 557723 CDS YP_002475113.1 219870738 7278506 545041..547044 1 NC_011852.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 547044 mnmC 7278506 mnmC Haemophilus parasuis SH0165 5-methylaminomethyl-2-thiouridine methyltransferase YP_002475113.1 545041 D 557723 CDS YP_002475114.1 219870739 7278507 complement(547171..547941) 1 NC_011852.1 COG:S;COG0327; hypothetical protein 547941 7278507 HAPS_0502 Haemophilus parasuis SH0165 hypothetical protein YP_002475114.1 547171 R 557723 CDS YP_002475115.1 219870740 7278510 complement(548331..549563) 1 NC_011852.1 COG:H;COG0303; molybdopterin biosynthesis protein MoeA 549563 moeA 7278510 moeA Haemophilus parasuis SH0165 molybdopterin biosynthesis protein MoeA YP_002475115.1 548331 R 557723 CDS YP_002475116.1 219870741 7278511 549821..550792 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 550792 7278511 HAPS_0506 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002475116.1 549821 D 557723 CDS YP_002475117.1 219870742 7278512 complement(550861..551484) 1 NC_011852.1 COG:U;COG2095; multiple antibiotic resistance (MarC)-like protein 551484 marC 7278512 marC Haemophilus parasuis SH0165 multiple antibiotic resistance (MarC)-like protein YP_002475117.1 550861 R 557723 CDS YP_002475118.1 219870743 7278514 complement(553596..553838) 1 NC_011852.1 hypothetical protein 553838 7278514 HAPS_0509 Haemophilus parasuis SH0165 hypothetical protein YP_002475118.1 553596 R 557723 CDS YP_002475119.1 219870744 7278515 complement(553807..555735) 1 NC_011852.1 COG:O;COG0465; cell division protein 555735 ftsH 7278515 ftsH Haemophilus parasuis SH0165 cell division protein YP_002475119.1 553807 R 557723 CDS YP_002475120.1 219870745 7278516 complement(555809..556435) 1 NC_011852.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 556435 rrmJ 7278516 rrmJ Haemophilus parasuis SH0165 23S rRNA methyltransferase J YP_002475120.1 555809 R 557723 CDS YP_002475121.1 219870746 7278517 556678..557466 1 NC_011852.1 COG:I;COG0623; enoyl-[acyl-carrier-protein] reductase (NADH) 557466 fabI 7278517 fabI Haemophilus parasuis SH0165 enoyl-[acyl-carrier-protein] reductase (NADH) YP_002475121.1 556678 D 557723 CDS YP_002475122.1 219870747 7278518 557546..558208 1 NC_011852.1 filamentation induced by cAMP protein fic 558208 fic 7278518 fic Haemophilus parasuis SH0165 filamentation induced by cAMP protein fic YP_002475122.1 557546 D 557723 CDS YP_002475123.1 219870748 7278519 complement(558266..558562) 1 NC_011852.1 COG:K;COG2944; putative helix-turn-helix containing protein 558562 7278519 HAPS_0514 Haemophilus parasuis SH0165 putative helix-turn-helix containing protein YP_002475123.1 558266 R 557723 CDS YP_002475124.1 219870749 7278520 complement(558565..558909) 1 NC_011852.1 COG:JD;COG2026; hypothetical protein 558909 7278520 HAPS_0515 Haemophilus parasuis SH0165 hypothetical protein YP_002475124.1 558565 R 557723 CDS YP_002475125.1 219870750 7278521 559124..561103 1 NC_011852.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 561103 rnb 7278521 rnb Haemophilus parasuis SH0165 exoribonuclease II YP_002475125.1 559124 D 557723 CDS YP_002475126.1 219870751 7278522 561214..562305 1 NC_011852.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 562305 mltA 7278522 mltA Haemophilus parasuis SH0165 murein transglycosylase A YP_002475126.1 561214 D 557723 CDS YP_002475127.1 219870752 7278523 562780..563196 1 NC_011852.1 hypothetical protein 563196 7278523 HAPS_0518 Haemophilus parasuis SH0165 hypothetical protein YP_002475127.1 562780 D 557723 CDS YP_002475128.1 219870753 7278525 complement(566989..567102) 1 NC_011852.1 hypothetical protein 567102 7278525 HAPS_0520 Haemophilus parasuis SH0165 hypothetical protein YP_002475128.1 566989 R 557723 CDS YP_002475129.1 219870754 7278526 complement(567452..568048) 1 NC_011852.1 COG:S;COG0586; DedA family integral membrane protein, hypothetical protein 568048 dedA 7278526 dedA Haemophilus parasuis SH0165 DedA family integral membrane protein, hypothetical protein YP_002475129.1 567452 R 557723 CDS YP_002475130.1 219870755 7278527 complement(568059..569081) 1 NC_011852.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 569081 purR 7278527 purR Haemophilus parasuis SH0165 DNA-binding transcriptional repressor PurR YP_002475130.1 568059 R 557723 CDS YP_002475131.1 219870756 7278528 complement(569195..570139) 1 NC_011852.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 570139 prmC 7278528 prmC Haemophilus parasuis SH0165 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002475131.1 569195 R 557723 CDS YP_002475132.1 219870757 7278529 570226..570756 1 NC_011852.1 COG:S;COG2840; hypothetical protein 570756 7278529 HAPS_0524 Haemophilus parasuis SH0165 hypothetical protein YP_002475132.1 570226 D 557723 CDS YP_002475133.1 219870758 7278530 complement(570898..572115) 1 NC_011852.1 COG:E;COG0814; tyrosine-specific transporter 572115 tyrP 7278530 tyrP Haemophilus parasuis SH0165 tyrosine-specific transporter YP_002475133.1 570898 R 557723 CDS YP_002475134.1 219870759 7278531 complement(572263..573417) 1 NC_011852.1 COG:E;COG0814; tyrosine-specific transporter 573417 tyrP 7278531 tyrP Haemophilus parasuis SH0165 tyrosine-specific transporter YP_002475134.1 572263 R 557723 CDS YP_002475135.1 219870760 7278533 complement(574273..574752) 1 NC_011852.1 COG:OC;COG0526; phosphoribosylformylglycinamidine synthase 574752 purL 7278533 purL Haemophilus parasuis SH0165 phosphoribosylformylglycinamidine synthase YP_002475135.1 574273 R 557723 CDS YP_002475136.1 219870761 7277266 complement(574770..575420) 1 NC_011852.1 COG:O;COG0785; cytochrome c-type biogenesis protein ccdA 575420 ccdA 7277266 ccdA Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein ccdA YP_002475136.1 574770 R 557723 CDS YP_002475137.1 219870762 7276679 complement(575422..576492) 1 NC_011852.1 COG:O;COG0225; bifunctional methionine sulfoxide reductase msrA/msrB 576492 msrA 7276679 msrA Haemophilus parasuis SH0165 bifunctional methionine sulfoxide reductase msrA/msrB YP_002475137.1 575422 R 557723 CDS YP_002475138.1 219870763 7276680 complement(576596..576925) 1 NC_011852.1 hypothetical protein 576925 7276680 HAPS_0531 Haemophilus parasuis SH0165 hypothetical protein YP_002475138.1 576596 R 557723 CDS YP_002475139.1 219870764 7276681 577169..577639 1 NC_011852.1 COG:K;COG1595; RNA polymerase sigma-70 factor 577639 rpoE 7276681 rpoE Haemophilus parasuis SH0165 RNA polymerase sigma-70 factor YP_002475139.1 577169 D 557723 CDS YP_002475140.1 219870765 7276682 577636..577821 1 NC_011852.1 hypothetical protein 577821 7276682 HAPS_0533 Haemophilus parasuis SH0165 hypothetical protein YP_002475140.1 577636 D 557723 CDS YP_002475141.1 219870766 7276685 579397..580212 1 NC_011852.1 phage capsid scaffolding protein 580212 7276685 HAPS_0536 Haemophilus parasuis SH0165 phage capsid scaffolding protein YP_002475141.1 579397 D 557723 CDS YP_002475142.1 219870767 7276687 580428..581081 1 NC_011852.1 phage small terminase subunit 581081 7276687 HAPS_0538 Haemophilus parasuis SH0165 phage small terminase subunit YP_002475142.1 580428 D 557723 CDS YP_002475143.1 219870768 7276689 581237..581761 1 NC_011852.1 COG:R;COG3772; phage-like lysozyme 581761 7276689 HAPS_0540 Haemophilus parasuis SH0165 phage-like lysozyme YP_002475143.1 581237 D 557723 CDS YP_002475144.1 219870769 7276690 581746..582213 1 NC_011852.1 hypothetical bacteriophage protein 582213 7276690 HAPS_0541 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475144.1 581746 D 557723 CDS YP_002475145.1 219870770 7276691 582396..582914 1 NC_011852.1 putative Lhr family helicase, phage associatd 582914 7276691 HAPS_0542 Haemophilus parasuis SH0165 putative Lhr family helicase, phage associatd YP_002475145.1 582396 D 557723 CDS YP_002475146.1 219870771 7276692 583120..583338 1 NC_011852.1 COG:T;COG1734; DnaK suppressor protein/ C4-type zinc finger protein, DksA/TraR family 583338 dnaK 7276692 dnaK Haemophilus parasuis SH0165 DnaK suppressor protein/ C4-type zinc finger protein, DksA/TraR family YP_002475146.1 583120 D 557723 CDS YP_002475147.1 219870772 7276693 583335..583769 1 NC_011852.1 bacteriophage P2 Tail completion protein GPR 583769 gpR 7276693 gpR Haemophilus parasuis SH0165 bacteriophage P2 Tail completion protein GPR YP_002475147.1 583335 D 557723 CDS YP_002475148.1 219870773 7276694 583810..584271 1 NC_011852.1 bacteriophage tail completion protein gpS-like protein/phage virion morphogenesis protein 584271 gpS 7276694 gpS Haemophilus parasuis SH0165 bacteriophage tail completion protein gpS-like protein/phage virion morphogenesis protein YP_002475148.1 583810 D 557723 CDS YP_002475149.1 219870774 7276695 complement(584367..584552) 1 NC_011852.1 hypothetical protein 584552 7276695 HAPS_0546 Haemophilus parasuis SH0165 hypothetical protein YP_002475149.1 584367 R 557723 CDS YP_002475150.1 219870775 7276696 584682..587423 1 NC_011852.1 COG:S;COG5283; bacteriophage P2 tail protein GPT; putative tail length determinator 587423 gpT 7276696 gpT Haemophilus parasuis SH0165 bacteriophage P2 tail protein GPT; putative tail length determinator YP_002475150.1 584682 D 557723 CDS YP_002475151.1 219870776 7276697 587550..588092 1 NC_011852.1 hypothetical protein 588092 7276697 HAPS_0548 Haemophilus parasuis SH0165 hypothetical protein YP_002475151.1 587550 D 557723 CDS YP_002475152.1 219870777 7276698 588085..588507 1 NC_011852.1 hypothetical protein 588507 7276698 HAPS_0549 Haemophilus parasuis SH0165 hypothetical protein YP_002475152.1 588085 D 557723 CDS YP_002475153.1 219870778 7276699 588682..588801 1 NC_011852.1 hypothetical protein 588801 7276699 HAPS_0550 Haemophilus parasuis SH0165 hypothetical protein YP_002475153.1 588682 D 557723 CDS YP_002475154.1 219870779 7276701 590265..590450 1 NC_011852.1 COG:N;COG1724; hypothetical protein 590450 ycfA 7276701 ycfA Haemophilus parasuis SH0165 hypothetical protein YP_002475154.1 590265 D 557723 CDS YP_002475155.1 219870780 7276702 590480..590917 1 NC_011852.1 COG:S;COG1598; hypothetical protein 590917 7276702 HAPS_0553 Haemophilus parasuis SH0165 hypothetical protein YP_002475155.1 590480 D 557723 CDS YP_002475156.1 219870781 7276703 complement(590939..591316) 1 NC_011852.1 putative phage anti-termination protein Q 591316 7276703 HAPS_0554 Haemophilus parasuis SH0165 putative phage anti-termination protein Q YP_002475156.1 590939 R 557723 CDS YP_002475157.1 219870782 7276704 complement(591313..591882) 1 NC_011852.1 NinG recombination protein/bacteriophage lambda NinG family protein 591882 ninG 7276704 ninG Haemophilus parasuis SH0165 NinG recombination protein/bacteriophage lambda NinG family protein YP_002475157.1 591313 R 557723 CDS YP_002475158.1 219870783 7276705 complement(592027..592476) 1 NC_011852.1 putative recombination protein NinB 592476 ninB 7276705 ninB Haemophilus parasuis SH0165 putative recombination protein NinB YP_002475158.1 592027 R 557723 CDS YP_002475159.1 219870784 7276706 complement(592711..593382) 1 NC_011852.1 putative bacteriophage replication protein P 593382 7276706 HAPS_0557 Haemophilus parasuis SH0165 putative bacteriophage replication protein P YP_002475159.1 592711 R 557723 CDS YP_002475160.1 219870785 7276707 complement(593382..594212) 1 NC_011852.1 putative phage DNA replication protein O 594212 7276707 HAPS_0558 Haemophilus parasuis SH0165 putative phage DNA replication protein O YP_002475160.1 593382 R 557723 CDS YP_002475161.1 219870786 7276708 complement(594209..594991) 1 NC_011852.1 prophage antirepressor DNA-binding protein (Roi) 594991 7276708 HAPS_0559 Haemophilus parasuis SH0165 prophage antirepressor DNA-binding protein (Roi) YP_002475161.1 594209 R 557723 CDS YP_002475162.1 219870787 7276709 complement(595271..595477) 1 NC_011852.1 prophage LambdaSo, Cro/CI family transcriptional regulator/ putative Cro repressor 595477 7276709 HAPS_0560 Haemophilus parasuis SH0165 prophage LambdaSo, Cro/CI family transcriptional regulator/ putative Cro repressor YP_002475162.1 595271 R 557723 CDS YP_002475163.1 219870788 7276710 595739..596266 1 NC_011852.1 COG:KT;COG1974; putative prophage repressor CI, XRE family transcriptional regulator/SOS-response transcriptional repressors (RecA-mediated autopeptidases)/ LexA family repressor/S24 family protease 596266 7276710 HAPS_0561 Haemophilus parasuis SH0165 putative prophage repressor CI, XRE family transcriptional regulator/SOS-response transcriptional repressors (RecA-mediated autopeptidases)/ LexA family repressor/S24 family protease YP_002475163.1 595739 D 557723 CDS YP_002475164.1 219870789 7276711 596299..596733 1 NC_011852.1 hypothetical protein 596733 7276711 HAPS_0562 Haemophilus parasuis SH0165 hypothetical protein YP_002475164.1 596299 D 557723 CDS YP_002475165.1 219870790 7276712 596726..597202 1 NC_011852.1 hypothetical protein 597202 7276712 HAPS_0563 Haemophilus parasuis SH0165 hypothetical protein YP_002475165.1 596726 D 557723 CDS YP_002475166.1 219870791 7276713 597320..597502 1 NC_011852.1 hypothetical protein 597502 ycfA 7276713 ycfA Haemophilus parasuis SH0165 hypothetical protein YP_002475166.1 597320 D 557723 CDS YP_002475167.1 219870792 7276714 597542..597961 1 NC_011852.1 COG:S;COG1598; putative bacteriophage protein transcription regulator, cro/C1-type DNA-binding domain 597961 7276714 HAPS_0565 Haemophilus parasuis SH0165 putative bacteriophage protein transcription regulator, cro/C1-type DNA-binding domain YP_002475167.1 597542 D 557723 CDS YP_002475168.1 219870793 7276715 598384..598539 1 NC_011852.1 hypothetical protein 598539 7276715 HAPS_0566 Haemophilus parasuis SH0165 hypothetical protein YP_002475168.1 598384 D 557723 CDS YP_002475169.1 219870794 7276716 598817..599104 1 NC_011852.1 hypothetical protein 599104 7276716 HAPS_0567 Haemophilus parasuis SH0165 hypothetical protein YP_002475169.1 598817 D 557723 CDS YP_002475170.1 219870795 7276717 complement(599131..599301) 1 NC_011852.1 COG:S;COG3422; hypothetical protein 599301 7276717 HAPS_0568 Haemophilus parasuis SH0165 hypothetical protein YP_002475170.1 599131 R 557723 CDS YP_002475171.1 219870796 7276718 599316..599537 1 NC_011852.1 hypothetical protein 599537 orfG 7276718 orfG Haemophilus parasuis SH0165 hypothetical protein YP_002475171.1 599316 D 557723 CDS YP_002475172.1 219870797 7276719 complement(599674..599802) 1 NC_011852.1 hypothetical protein 599802 7276719 HAPS_0570 Haemophilus parasuis SH0165 hypothetical protein YP_002475172.1 599674 R 557723 CDS YP_002475173.1 219870798 7276720 599879..600520 1 NC_011852.1 hypothetical protein 600520 7276720 HAPS_0571 Haemophilus parasuis SH0165 hypothetical protein YP_002475173.1 599879 D 557723 CDS YP_002475174.1 219870799 7276721 600597..600725 1 NC_011852.1 hypothetical protein 600725 7276721 HAPS_0572 Haemophilus parasuis SH0165 hypothetical protein YP_002475174.1 600597 D 557723 CDS YP_002475175.1 219870800 7276722 600730..601443 1 NC_011852.1 protein serine/threonine phosphatase, protein phosphatase 2C-like protein 601443 7276722 HAPS_0573 Haemophilus parasuis SH0165 protein serine/threonine phosphatase, protein phosphatase 2C-like protein YP_002475175.1 600730 D 557723 CDS YP_002475176.1 219870801 7276724 601989..602309 1 NC_011852.1 hypothetical protein 602309 7276724 HAPS_0575 Haemophilus parasuis SH0165 hypothetical protein YP_002475176.1 601989 D 557723 CDS YP_002475177.1 219870802 7276725 602306..602845 1 NC_011852.1 hypothetical protein 602845 7276725 HAPS_0576 Haemophilus parasuis SH0165 hypothetical protein YP_002475177.1 602306 D 557723 CDS YP_002475178.1 219870803 7276726 602832..603038 1 NC_011852.1 hypothetical protein 603038 7276726 HAPS_0577 Haemophilus parasuis SH0165 hypothetical protein YP_002475178.1 602832 D 557723 CDS YP_002475179.1 219870804 7276727 603035..603973 1 NC_011852.1 COG:L;COG3723; phage recombinase, recombinational DNA repair protein, RecE pathway 603973 7276727 HAPS_0578 Haemophilus parasuis SH0165 phage recombinase, recombinational DNA repair protein, RecE pathway YP_002475179.1 603035 D 557723 CDS YP_002475180.1 219870805 7276728 604027..604695 1 NC_011852.1 hypothetical protein 604695 7276728 HAPS_0579 Haemophilus parasuis SH0165 hypothetical protein YP_002475180.1 604027 D 557723 CDS YP_002475181.1 219870806 7276729 604695..605174 1 NC_011852.1 COG:L;COG0629; single-stranded DNA binding protein 605174 ssb 7276729 ssb Haemophilus parasuis SH0165 single-stranded DNA binding protein YP_002475181.1 604695 D 557723 CDS YP_002475182.1 219870807 7276730 complement(605220..605408) 1 NC_011852.1 hypothetical protein 605408 7276730 HAPS_0581 Haemophilus parasuis SH0165 hypothetical protein YP_002475182.1 605220 R 557723 CDS YP_002475183.1 219870808 7276731 605755..606672 1 NC_011852.1 intrrupted gp229, phage associated 606672 7276731 HAPS_0582 Haemophilus parasuis SH0165 intrrupted gp229, phage associated YP_002475183.1 605755 D 557723 CDS YP_002475184.1 219870809 7276732 606696..606959 1 NC_011852.1 hypothetical protein 606959 7276732 HAPS_0583 Haemophilus parasuis SH0165 hypothetical protein YP_002475184.1 606696 D 557723 CDS YP_002475185.1 219870810 7276733 complement(607103..607321) 1 NC_011852.1 hypothetical protein 607321 7276733 HAPS_0584 Haemophilus parasuis SH0165 hypothetical protein YP_002475185.1 607103 R 557723 CDS YP_002475186.1 219870811 7276734 complement(607748..608044) 1 NC_011852.1 hypothetical protein 608044 7276734 HAPS_0585 Haemophilus parasuis SH0165 hypothetical protein YP_002475186.1 607748 R 557723 CDS YP_002475187.1 219870812 7276735 complement(608153..609130) 1 NC_011852.1 hypothetical protein 609130 7276735 HAPS_0586 Haemophilus parasuis SH0165 hypothetical protein YP_002475187.1 608153 R 557723 CDS YP_002475188.1 219870813 7276736 complement(609187..614070) 1 NC_011852.1 COG:S;COG4733; phage tail protein/putative Fels-1 prophage host specificity protein 614070 7276736 HAPS_0587 Haemophilus parasuis SH0165 phage tail protein/putative Fels-1 prophage host specificity protein YP_002475188.1 609187 R 557723 CDS YP_002475189.1 219870814 7276737 complement(614189..615034) 1 NC_011852.1 COG:K;COG3617; putative antirepressor protein 615034 7276737 HAPS_0588 Haemophilus parasuis SH0165 putative antirepressor protein YP_002475189.1 614189 R 557723 CDS YP_002475190.1 219870815 7276738 complement(615298..615483) 1 NC_011852.1 hypothetical protein 615483 7276738 HAPS_0589 Haemophilus parasuis SH0165 hypothetical protein YP_002475190.1 615298 R 557723 CDS YP_002475191.1 219870816 7276739 complement(615597..616115) 1 NC_011852.1 COG:S;COG4723; bacteriophage lambda tail assembly I 616115 7276739 HAPS_0590 Haemophilus parasuis SH0165 bacteriophage lambda tail assembly I YP_002475191.1 615597 R 557723 CDS YP_002475192.1 219870817 7276740 complement(616145..616897) 1 NC_011852.1 phage-like tail assembly protein K 616897 7276740 HAPS_0591 Haemophilus parasuis SH0165 phage-like tail assembly protein K YP_002475192.1 616145 R 557723 CDS YP_002475193.1 219870818 7276741 complement(616899..617636) 1 NC_011852.1 COG:S;COG4672; phage-like minor tail protein L 617636 7276741 HAPS_0592 Haemophilus parasuis SH0165 phage-like minor tail protein L YP_002475193.1 616899 R 557723 CDS YP_002475194.1 219870819 7276742 complement(617636..617968) 1 NC_011852.1 COG:S;COG4718; putative phage minor tail protein 617968 7276742 HAPS_0593 Haemophilus parasuis SH0165 putative phage minor tail protein YP_002475194.1 617636 R 557723 CDS YP_002475195.1 219870820 7276743 complement(618013..621387) 1 NC_011852.1 phage-like minor tail protein 621387 7276743 HAPS_0594 Haemophilus parasuis SH0165 phage-like minor tail protein YP_002475195.1 618013 R 557723 CDS YP_002475196.1 219870821 7276744 complement(621443..621718) 1 NC_011852.1 hypothetical protein 621718 7276744 HAPS_0595 Haemophilus parasuis SH0165 hypothetical protein YP_002475196.1 621443 R 557723 CDS YP_002475197.1 219870822 7276745 complement(621920..622186) 1 NC_011852.1 hypothetical protein 622186 7276745 HAPS_0596 Haemophilus parasuis SH0165 hypothetical protein YP_002475197.1 621920 R 557723 CDS YP_002475198.1 219870823 7276746 complement(622270..622539) 1 NC_011852.1 COG:S;COG3041; addiction module antitoxin 622539 relE 7276746 relE Haemophilus parasuis SH0165 addiction module antitoxin YP_002475198.1 622270 R 557723 CDS YP_002475199.1 219870824 7276747 complement(622543..622809) 1 NC_011852.1 COG:L;COG3077; RelB, addiction module antitoxin/DNA-damage-inducible protein J, negative regulator of translation 622809 relB 7276747 relB Haemophilus parasuis SH0165 RelB, addiction module antitoxin/DNA-damage-inducible protein J, negative regulator of translation YP_002475199.1 622543 R 557723 CDS YP_002475200.1 219870825 7276748 complement(622878..623105) 1 NC_011852.1 phage protein 623105 7276748 HAPS_0599 Haemophilus parasuis SH0165 phage protein YP_002475200.1 622878 R 557723 CDS YP_002475201.1 219870826 7276749 complement(623150..623551) 1 NC_011852.1 phage protein 623551 7276749 HAPS_0600 Haemophilus parasuis SH0165 phage protein YP_002475201.1 623150 R 557723 CDS YP_002475202.1 219870827 7276750 complement(623625..624290) 1 NC_011852.1 phage protein 624290 7276750 HAPS_0601 Haemophilus parasuis SH0165 phage protein YP_002475202.1 623625 R 557723 CDS YP_002475203.1 219870828 7276751 complement(624293..624712) 1 NC_011852.1 putative tail component of prophage CP-933K 624712 7276751 HAPS_0602 Haemophilus parasuis SH0165 putative tail component of prophage CP-933K YP_002475203.1 624293 R 557723 CDS YP_002475204.1 219870829 7276752 complement(624712..625245) 1 NC_011852.1 putative phage tail component 625245 7276752 HAPS_0603 Haemophilus parasuis SH0165 putative phage tail component YP_002475204.1 624712 R 557723 CDS YP_002475205.1 219870830 7276753 complement(625249..625551) 1 NC_011852.1 putative bacteriophage tail protein 625551 7276753 HAPS_0604 Haemophilus parasuis SH0165 putative bacteriophage tail protein YP_002475205.1 625249 R 557723 CDS YP_002475206.1 219870831 7276754 complement(625544..625870) 1 NC_011852.1 COG:S;COG5471; putative RecA/RadA recombinase 625870 7276754 HAPS_0605 Haemophilus parasuis SH0165 putative RecA/RadA recombinase YP_002475206.1 625544 R 557723 CDS YP_002475207.1 219870832 7276755 complement(625938..627905) 1 NC_011852.1 Clp protease-like protein 627905 7276755 HAPS_0606 Haemophilus parasuis SH0165 Clp protease-like protein YP_002475207.1 625938 R 557723 CDS YP_002475208.1 219870833 7276756 complement(627930..629429) 1 NC_011852.1 COG:R;COG5511; bacteriophage capsid protein 629429 7276756 HAPS_0607 Haemophilus parasuis SH0165 bacteriophage capsid protein YP_002475208.1 627930 R 557723 CDS YP_002475209.1 219870834 7276757 complement(629430..629651) 1 NC_011852.1 hypothetical protein 629651 7276757 HAPS_0608 Haemophilus parasuis SH0165 hypothetical protein YP_002475209.1 629430 R 557723 CDS YP_002475210.1 219870835 7276758 complement(629669..631789) 1 NC_011852.1 COG:R;COG5525; bacteriophage tail assembly protein/phage terminase large subunit 631789 7276758 HAPS_0609 Haemophilus parasuis SH0165 bacteriophage tail assembly protein/phage terminase large subunit YP_002475210.1 629669 R 557723 CDS YP_002475211.1 219870836 7276759 complement(631789..632301) 1 NC_011852.1 similar to protein encoded by prophage CP-933K; hypothetical protein 632301 7276759 HAPS_0610 Haemophilus parasuis SH0165 hypothetical protein YP_002475211.1 631789 R 557723 CDS YP_002475212.1 219870837 7276761 complement(632341..632787) 1 NC_011852.1 putative lytic protein Rz1, bacteriophage protein 632787 7276761 HAPS_0611 Haemophilus parasuis SH0165 putative lytic protein Rz1, bacteriophage protein YP_002475212.1 632341 R 557723 CDS YP_002475213.1 219870838 7276763 complement(632750..633067) 1 NC_011852.1 hypothetical bacteriophage protein 633067 7276763 HAPS_0612 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475213.1 632750 R 557723 CDS YP_002475214.1 219870839 7276764 complement(633067..633612) 1 NC_011852.1 COG:R;COG3772; glycoside hydrolase family protein/phage lysozyme 633612 7276764 HAPS_0613 Haemophilus parasuis SH0165 glycoside hydrolase family protein/phage lysozyme YP_002475214.1 633067 R 557723 CDS YP_002475215.1 219870840 7276765 complement(633587..633862) 1 NC_011852.1 hypothetical protein 633862 7276765 HAPS_0614 Haemophilus parasuis SH0165 hypothetical protein YP_002475215.1 633587 R 557723 CDS YP_002475216.1 219870841 7276766 633976..634539 1 NC_011852.1 hypothetical protein 634539 7276766 HAPS_0615 Haemophilus parasuis SH0165 hypothetical protein YP_002475216.1 633976 D 557723 CDS YP_002475217.1 219870842 7276767 634629..634745 1 NC_011852.1 hypothetical protein 634745 7276767 HAPS_0616 Haemophilus parasuis SH0165 hypothetical protein YP_002475217.1 634629 D 557723 CDS YP_002475218.1 219870843 7276768 complement(634831..635007) 1 NC_011852.1 hypothetical protein 635007 7276768 HAPS_0617 Haemophilus parasuis SH0165 hypothetical protein YP_002475218.1 634831 R 557723 CDS YP_002475219.1 219870844 7276769 635304..635522 1 NC_011852.1 hypothetical protein 635522 7276769 HAPS_0618 Haemophilus parasuis SH0165 hypothetical protein YP_002475219.1 635304 D 557723 CDS YP_002475220.1 219870845 7276770 complement(635531..635908) 1 NC_011852.1 putative anti-termination protein Q, phage associated 635908 7276770 HAPS_0619 Haemophilus parasuis SH0165 putative anti-termination protein Q, phage associated YP_002475220.1 635531 R 557723 CDS YP_002475221.1 219870846 7276771 complement(635905..636474) 1 NC_011852.1 NinG recombination protein/bacteriophage lambda NinG family protein 636474 ninG 7276771 ninG Haemophilus parasuis SH0165 NinG recombination protein/bacteriophage lambda NinG family protein YP_002475221.1 635905 R 557723 CDS YP_002475222.1 219870847 7276772 complement(636619..637068) 1 NC_011852.1 putative recombination protein NinB 637068 ninB 7276772 ninB Haemophilus parasuis SH0165 putative recombination protein NinB YP_002475222.1 636619 R 557723 CDS YP_002475223.1 219870848 7276773 complement(637303..637974) 1 NC_011852.1 replication protein P/putative bacteriophage replication protein 637974 7276773 HAPS_0622 Haemophilus parasuis SH0165 replication protein P/putative bacteriophage replication protein YP_002475223.1 637303 R 557723 CDS YP_002475224.1 219870849 7276774 complement(637974..638804) 1 NC_011852.1 putative phage DNA replication protein O 638804 7276774 HAPS_0623 Haemophilus parasuis SH0165 putative phage DNA replication protein O YP_002475224.1 637974 R 557723 CDS YP_002475225.1 219870850 7276775 complement(638801..639583) 1 NC_011852.1 prophage antirepressor protein 1/putative DNA-binding protein (Roi) 639583 7276775 HAPS_0624 Haemophilus parasuis SH0165 prophage antirepressor protein 1/putative DNA-binding protein (Roi) YP_002475225.1 638801 R 557723 CDS YP_002475226.1 219870851 7276776 complement(639863..640063) 1 NC_011852.1 phage transcriptional regulatory protein/antirepressor Cro 640063 7276776 HAPS_0625 Haemophilus parasuis SH0165 phage transcriptional regulatory protein/antirepressor Cro YP_002475226.1 639863 R 557723 CDS YP_002475227.1 219870852 7276777 640190..640861 1 NC_011852.1 COG:K;COG2932; transcriptional activator-regulator PrtR/CI repressor 640861 prtR 7276777 prtR Haemophilus parasuis SH0165 transcriptional activator-regulator PrtR/CI repressor YP_002475227.1 640190 D 557723 CDS YP_002475228.1 219870853 7276778 640942..641790 1 NC_011852.1 hypothetical protein 641790 7276778 HAPS_0627 Haemophilus parasuis SH0165 hypothetical protein YP_002475228.1 640942 D 557723 CDS YP_002475229.1 219870854 7276779 641924..643567 1 NC_011852.1 putative prophage Lp2 protein 4 643567 7276779 HAPS_0628 Haemophilus parasuis SH0165 putative prophage Lp2 protein 4 YP_002475229.1 641924 D 557723 CDS YP_002475230.1 219870855 7276780 643612..644427 1 NC_011852.1 COG:L;COG0338; site-specific DNA methylase 644427 dam 7276780 dam Haemophilus parasuis SH0165 site-specific DNA methylase YP_002475230.1 643612 D 557723 CDS YP_002475231.1 219870856 7276781 complement(644456..644746) 1 NC_011852.1 COG:K;COG3636; putative transcriptional regulator/addiction module antitoxin 644746 7276781 HAPS_0630 Haemophilus parasuis SH0165 putative transcriptional regulator/addiction module antitoxin YP_002475231.1 644456 R 557723 CDS YP_002475232.1 219870857 7276782 644806..645252 1 NC_011852.1 hypothetical protein 645252 7276782 HAPS_0631 Haemophilus parasuis SH0165 hypothetical protein YP_002475232.1 644806 D 557723 CDS YP_002475233.1 219870858 7276783 complement(645697..645867) 1 NC_011852.1 COG:S;COG3422; hypothetical protein 645867 7276783 HAPS_0632 Haemophilus parasuis SH0165 hypothetical protein YP_002475233.1 645697 R 557723 CDS YP_002475234.1 219870859 7276784 645882..646103 1 NC_011852.1 hypothetical protein 646103 orfG 7276784 orfG Haemophilus parasuis SH0165 hypothetical protein YP_002475234.1 645882 D 557723 CDS YP_002475235.1 219870860 7276785 complement(646083..646259) 1 NC_011852.1 hypothetical protein 646259 7276785 HAPS_0634 Haemophilus parasuis SH0165 hypothetical protein YP_002475235.1 646083 R 557723 CDS YP_002475236.1 219870861 7276787 646599..647240 1 NC_011852.1 hypothetical protein 647240 7276787 HAPS_0636 Haemophilus parasuis SH0165 hypothetical protein YP_002475236.1 646599 D 557723 CDS YP_002475237.1 219870862 7276788 complement(647314..647535) 1 NC_011852.1 hypothetical protein 647535 7276788 HAPS_0637 Haemophilus parasuis SH0165 hypothetical protein YP_002475237.1 647314 R 557723 CDS YP_002475238.1 219870863 7276789 647625..647786 1 NC_011852.1 hypothetical protein 647786 7276789 HAPS_0638 Haemophilus parasuis SH0165 hypothetical protein YP_002475238.1 647625 D 557723 CDS YP_002475239.1 219870864 7276790 complement(647757..647945) 1 NC_011852.1 hypothetical protein 647945 7276790 HAPS_0639 Haemophilus parasuis SH0165 hypothetical protein YP_002475239.1 647757 R 557723 CDS YP_002475240.1 219870865 7276794 complement(651109..651927) 1 NC_011852.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 651927 apaH 7276794 apaH Haemophilus parasuis SH0165 diadenosine tetraphosphatase YP_002475240.1 651109 R 557723 CDS YP_002475241.1 219870866 7276795 complement(651937..653016) 1 NC_011852.1 COG:M;COG2951; membrane-bound lytic murein transglycosylase B 653016 mltB 7276795 mltB Haemophilus parasuis SH0165 membrane-bound lytic murein transglycosylase B YP_002475241.1 651937 R 557723 CDS YP_002475242.1 219870867 7276796 complement(653029..653946) 1 NC_011852.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 653946 truB 7276796 truB Haemophilus parasuis SH0165 tRNA pseudouridine synthase B YP_002475242.1 653029 R 557723 CDS YP_002475243.1 219870868 7276797 complement(653949..654332) 1 NC_011852.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 654332 rbfA 7276797 rbfA Haemophilus parasuis SH0165 ribosome-binding factor A YP_002475243.1 653949 R 557723 CDS YP_002475244.1 219870869 7276798 complement(654375..654494) 1 NC_011852.1 hypothetical protein 654494 7276798 HAPS_0647 Haemophilus parasuis SH0165 hypothetical protein YP_002475244.1 654375 R 557723 CDS YP_002475245.1 219870870 7276799 complement(654502..657681) 1 NC_011852.1 putative serine protease 657681 7276799 HAPS_0648 Haemophilus parasuis SH0165 putative serine protease YP_002475245.1 654502 R 557723 CDS YP_002475246.1 219870871 7276801 complement(658373..658660) 1 NC_011852.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 658660 rplY 7276801 rplY Haemophilus parasuis SH0165 50S ribosomal protein L25 YP_002475246.1 658373 R 557723 CDS YP_002475247.1 219870872 7276802 658942..661455 1 NC_011852.1 COG:G;COG0058; glycogen phosphorylase 661455 glgP 7276802 glgP Haemophilus parasuis SH0165 glycogen phosphorylase YP_002475247.1 658942 D 557723 CDS YP_002475248.1 219870873 7276803 661674..662297 1 NC_011852.1 COG:R;COG1279; lysine exporter protein LysE/YggA 662297 lysE 7276803 lysE Haemophilus parasuis SH0165 lysine exporter protein LysE/YggA YP_002475248.1 661674 D 557723 CDS YP_002475249.1 219870874 7276804 662543..665350 1 NC_011852.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 665350 sucA 7276804 sucA Haemophilus parasuis SH0165 2-oxoglutarate dehydrogenase E1 component YP_002475249.1 662543 D 557723 CDS YP_002475250.1 219870875 7276805 665386..665499 1 NC_011852.1 hypothetical protein 665499 7276805 HAPS_0654 Haemophilus parasuis SH0165 hypothetical protein YP_002475250.1 665386 D 557723 CDS YP_002475251.1 219870876 7276806 665515..666732 1 NC_011852.1 COG:C;COG0508; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) 666732 sucB 7276806 sucB Haemophilus parasuis SH0165 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) YP_002475251.1 665515 D 557723 CDS YP_002475252.1 219870877 7276807 666797..667963 1 NC_011852.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 667963 sucC 7276807 sucC Haemophilus parasuis SH0165 succinyl-CoA synthetase subunit beta YP_002475252.1 666797 D 557723 CDS YP_002475253.1 219870878 7276808 667963..668835 1 NC_011852.1 COG:C;COG0074; succinyl-CoA synthetase alpha chain 668835 sucD 7276808 sucD Haemophilus parasuis SH0165 succinyl-CoA synthetase alpha chain YP_002475253.1 667963 D 557723 CDS YP_002475254.1 219870879 7276809 complement(668996..670846) 1 NC_011852.1 COG:P;COG0475; glutathione-regulated potassium-efflux system protein 670846 kefBC 7276809 kefBC Haemophilus parasuis SH0165 glutathione-regulated potassium-efflux system protein YP_002475254.1 668996 R 557723 CDS YP_002475255.1 219870880 7276810 complement(671041..672345) 1 NC_011852.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 672345 serS 7276810 serS Haemophilus parasuis SH0165 seryl-tRNA synthetase YP_002475255.1 671041 R 557723 CDS YP_002475256.1 219870881 7276811 complement(672421..672780) 1 NC_011852.1 COG:S;COG2852; glycyl-tRNA synthetase subunit alpha 672780 glyQ 7276811 glyQ Haemophilus parasuis SH0165 glycyl-tRNA synthetase subunit alpha YP_002475256.1 672421 R 557723 CDS YP_002475257.1 219870882 7276812 complement(673049..673525) 1 NC_011852.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 673525 smpB 7276812 smpB Haemophilus parasuis SH0165 SsrA-binding protein YP_002475257.1 673049 R 557723 CDS YP_002475258.1 219870883 7276813 complement(673648..675054) 1 NC_011852.1 COG:R;COG3106; hypothetical protein 675054 7276813 HAPS_0662 Haemophilus parasuis SH0165 hypothetical protein YP_002475258.1 673648 R 557723 CDS YP_002475259.1 219870884 7276814 complement(675065..676264) 1 NC_011852.1 COG:HC;COG0654; 2-octaprenyl-6-methoxyphenol hydroxylase 676264 ubiH 7276814 ubiH Haemophilus parasuis SH0165 2-octaprenyl-6-methoxyphenol hydroxylase YP_002475259.1 675065 R 557723 CDS YP_002475260.1 219870885 7276815 complement(676394..677437) 1 NC_011852.1 COG:E;COG0709; selenophosphate synthase 677437 selD 7276815 selD Haemophilus parasuis SH0165 selenophosphate synthase YP_002475260.1 676394 R 557723 CDS YP_002475261.1 219870886 7276816 complement(677540..677764) 1 NC_011852.1 COG:S;COG3036; hypothetical protein 677764 7276816 HAPS_0665 Haemophilus parasuis SH0165 hypothetical protein YP_002475261.1 677540 R 557723 CDS YP_002475262.1 219870887 7276817 677822..677935 1 NC_011852.1 hypothetical protein 677935 7276817 HAPS_0666 Haemophilus parasuis SH0165 hypothetical protein YP_002475262.1 677822 D 557723 CDS YP_002475263.1 219870888 7276818 677972..678727 1 NC_011852.1 COG:QR;COG0500; putative SAM-dependent methyltransferase 678727 7276818 HAPS_0667 Haemophilus parasuis SH0165 putative SAM-dependent methyltransferase YP_002475263.1 677972 D 557723 CDS YP_002475264.1 219870889 7276819 678964..680028 1 NC_011852.1 COG:R;COG0628; putative permease, PerM family protein 680028 perM 7276819 perM Haemophilus parasuis SH0165 putative permease, PerM family protein YP_002475264.1 678964 D 557723 CDS YP_002475265.1 219870890 7276820 680130..681215 1 NC_011852.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 681215 queA 7276820 queA Haemophilus parasuis SH0165 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002475265.1 680130 D 557723 CDS YP_002475266.1 219870891 7276821 complement(681324..682244) 1 NC_011852.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 682244 fdhE 7276821 fdhE Haemophilus parasuis SH0165 formate dehydrogenase accessory protein FdhE YP_002475266.1 681324 R 557723 CDS YP_002475267.1 219870892 7276822 complement(682287..684227) 1 NC_011852.1 COG:M;COG1368; phosphoglycerol transferase-like protein 684227 mdoB 7276822 mdoB Haemophilus parasuis SH0165 phosphoglycerol transferase-like protein YP_002475267.1 682287 R 557723 CDS YP_002475268.1 219870893 7276823 complement(684232..685020) 1 NC_011852.1 COG:R;COG3217; putative 2Fe-2S cluster-containing protein 685020 ycbX 7276823 ycbX Haemophilus parasuis SH0165 putative 2Fe-2S cluster-containing protein YP_002475268.1 684232 R 557723 CDS YP_002475269.1 219870894 7276824 685122..685346 1 NC_011852.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 685346 xseB 7276824 xseB Haemophilus parasuis SH0165 exodeoxyribonuclease VII small subunit YP_002475269.1 685122 D 557723 CDS YP_002475270.1 219870895 7276825 685346..686239 1 NC_011852.1 COG:H;COG0142; geranyltranstransferase 686239 ispA 7276825 ispA Haemophilus parasuis SH0165 geranyltranstransferase YP_002475270.1 685346 D 557723 CDS YP_002475271.1 219870896 7276826 complement(686285..687652) 1 NC_011852.1 hypothetical protein 687652 7276826 HAPS_0675 Haemophilus parasuis SH0165 hypothetical protein YP_002475271.1 686285 R 557723 CDS YP_002475272.1 219870897 7276827 complement(687702..689822) 1 NC_011852.1 COG:I;COG1250; fatty oxidation complex subunit alpha 689822 fadJ 7276827 fadJ Haemophilus parasuis SH0165 fatty oxidation complex subunit alpha YP_002475272.1 687702 R 557723 CDS YP_002475273.1 219870898 7276828 complement(689827..691131) 1 NC_011852.1 COG:I;COG0183; 3-ketoacyl-CoA thiolase 691131 fadI 7276828 fadI Haemophilus parasuis SH0165 3-ketoacyl-CoA thiolase YP_002475273.1 689827 R 557723 CDS YP_002475274.1 219870899 7276829 complement(691243..691944) 1 NC_011852.1 COG:S;COG1556; putative conserved iron-sulfur protein 691944 7276829 HAPS_0678 Haemophilus parasuis SH0165 putative conserved iron-sulfur protein YP_002475274.1 691243 R 557723 CDS YP_002475275.1 219870900 7276830 complement(691949..693355) 1 NC_011852.1 COG:C;COG1139; iron-sulfur cluster binding reductase 693355 7276830 HAPS_0679 Haemophilus parasuis SH0165 iron-sulfur cluster binding reductase YP_002475275.1 691949 R 557723 CDS YP_002475276.1 219870901 7276831 complement(693357..694088) 1 NC_011852.1 COG:C;COG0247; Fe-S oxidoreductase 694088 7276831 HAPS_0680 Haemophilus parasuis SH0165 Fe-S oxidoreductase YP_002475276.1 693357 R 557723 CDS YP_002475277.1 219870902 7276832 complement(694300..695895) 1 NC_011852.1 COG:C;COG1620; L-lactate permease 695895 lctP 7276832 lctP Haemophilus parasuis SH0165 L-lactate permease YP_002475277.1 694300 R 557723 CDS YP_002475278.1 219870903 7276833 complement(696084..696581) 1 NC_011852.1 COG:H;COG0262; dihydrofolate reductase 696581 folA 7276833 folA Haemophilus parasuis SH0165 dihydrofolate reductase YP_002475278.1 696084 R 557723 CDS YP_002475279.1 219870904 7276834 696664..697764 1 NC_011852.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 697764 proB 7276834 proB Haemophilus parasuis SH0165 gamma-glutamyl kinase YP_002475279.1 696664 D 557723 CDS YP_002475280.1 219870905 7276835 697787..698560 1 NC_011852.1 COG:R;COG0730; putative permease 698560 7276835 HAPS_0684 Haemophilus parasuis SH0165 putative permease YP_002475280.1 697787 D 557723 CDS YP_002475281.1 219870906 7276836 698564..699199 1 NC_011852.1 COG:L;COG0177; endonuclease III 699199 nth 7276836 nth Haemophilus parasuis SH0165 endonuclease III YP_002475281.1 698564 D 557723 CDS YP_002475282.1 219870907 7276839 complement(703117..703725) 1 NC_011852.1 COG:T;COG3103; SH3 domain-containing protein 703725 7276839 HAPS_0688 Haemophilus parasuis SH0165 SH3 domain-containing protein YP_002475282.1 703117 R 557723 CDS YP_002475283.1 219870908 7276840 complement(703799..705061) 1 NC_011852.1 COG:P;COG0306; phosphate permease 705061 7276840 HAPS_0689 Haemophilus parasuis SH0165 phosphate permease YP_002475283.1 703799 R 557723 CDS YP_002475284.1 219870909 7276841 complement(705081..705761) 1 NC_011852.1 COG:P;COG1392; phosphate transport regulator 705761 7276841 HAPS_0690 Haemophilus parasuis SH0165 phosphate transport regulator YP_002475284.1 705081 R 557723 CDS YP_002475285.1 219870910 7276842 706071..707054 1 NC_011852.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 707054 pheS 7276842 pheS Haemophilus parasuis SH0165 phenylalanyl-tRNA synthetase subunit alpha YP_002475285.1 706071 D 557723 CDS YP_002475286.1 219870911 7276843 707227..709614 1 NC_011852.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 709614 pheT 7276843 pheT Haemophilus parasuis SH0165 phenylalanyl-tRNA synthetase subunit beta YP_002475286.1 707227 D 557723 CDS YP_002475287.1 219870912 7278616 709631..709927 1 NC_011852.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 709927 ihfA 7278616 ihfA Haemophilus parasuis SH0165 integration host factor subunit alpha YP_002475287.1 709631 D 557723 CDS YP_002475288.1 219870913 7278209 709980..710492 1 NC_011852.1 COG:M;COG0791; lipoprotein/cell wall-associated hydrolases (invasion-associated proteins), NLP/P60 protein 710492 7278209 HAPS_0694 Haemophilus parasuis SH0165 lipoprotein/cell wall-associated hydrolases (invasion-associated proteins), NLP/P60 protein YP_002475288.1 709980 D 557723 CDS YP_002475289.1 219870914 7278210 710680..711333 1 NC_011852.1 COG:F;COG0572; uridine kinase 711333 udk 7278210 udk Haemophilus parasuis SH0165 uridine kinase YP_002475289.1 710680 D 557723 CDS YP_002475290.1 219870915 7278211 711350..711934 1 NC_011852.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 711934 dcd 7278211 dcd Haemophilus parasuis SH0165 deoxycytidine triphosphate deaminase YP_002475290.1 711350 D 557723 CDS YP_002475291.1 219870916 7278212 complement(712065..713579) 1 NC_011852.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 713579 purF 7278212 purF Haemophilus parasuis SH0165 amidophosphoribosyltransferase YP_002475291.1 712065 R 557723 CDS YP_002475292.1 219870917 7278213 complement(713594..714094) 1 NC_011852.1 COG:R;COG1286; colicin V production protein 714094 cvpA 7278213 cvpA Haemophilus parasuis SH0165 colicin V production protein YP_002475292.1 713594 R 557723 CDS YP_002475293.1 219870918 7278214 complement(714200..715777) 1 NC_011852.1 succinate dehydrogenase/fumarate reductase, flavoprotein subunit 715777 sdhA 7278214 sdhA Haemophilus parasuis SH0165 succinate dehydrogenase/fumarate reductase, flavoprotein subunit YP_002475293.1 714200 R 557723 CDS YP_002475294.1 219870919 7278215 complement(715952..716689) 1 NC_011852.1 COG:S;COG1496; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 716689 trmU 7278215 trmU Haemophilus parasuis SH0165 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_002475294.1 715952 R 557723 CDS YP_002475295.1 219870920 7278216 complement(716693..717082) 1 NC_011852.1 COG:J;COG0251; putative translation initiation inhibitor, yjgF family 717082 yjgF 7278216 yjgF Haemophilus parasuis SH0165 putative translation initiation inhibitor, yjgF family YP_002475295.1 716693 R 557723 CDS YP_002475296.1 219870921 7278217 717228..717515 1 NC_011852.1 COG:S;COG4453; putative ABC-type transporter 717515 7278217 HAPS_0702 Haemophilus parasuis SH0165 putative ABC-type transporter YP_002475296.1 717228 D 557723 CDS YP_002475297.1 219870922 7278218 717505..718005 1 NC_011852.1 COG:KR;COG0454; GNAT family acetyltransferase 718005 7278218 HAPS_0703 Haemophilus parasuis SH0165 GNAT family acetyltransferase YP_002475297.1 717505 D 557723 CDS YP_002475298.1 219870923 7278219 718033..719034 1 NC_011852.1 COG:R;COG3081; nucleoid-associated protein NdpA 719034 ndpA 7278219 ndpA Haemophilus parasuis SH0165 nucleoid-associated protein NdpA YP_002475298.1 718033 D 557723 CDS YP_002475299.1 219870924 7278220 719095..719430 1 NC_011852.1 possibly involved in in maintaining the structural integrity of the cell envelope; COG:J;COG2913; SmpA/OmlA domain-containing protein 719430 smpA 7278220 smpA Haemophilus parasuis SH0165 SmpA/OmlA domain-containing protein YP_002475299.1 719095 D 557723 CDS YP_002475300.1 219870925 7278221 719585..720700 1 NC_011852.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 720700 anmK 7278221 anmK Haemophilus parasuis SH0165 anhydro-N-acetylmuramic acid kinase YP_002475300.1 719585 D 557723 CDS YP_002475301.1 219870926 7278222 720712..721626 1 NC_011852.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 721626 murQ 7278222 murQ Haemophilus parasuis SH0165 N-acetylmuramic acid 6-phosphate etherase YP_002475301.1 720712 D 557723 CDS YP_002475302.1 219870927 7278223 721668..721982 1 NC_011852.1 COG:S;COG3098; hypothetical protein 721982 7278223 HAPS_0708 Haemophilus parasuis SH0165 hypothetical protein YP_002475302.1 721668 D 557723 CDS YP_002475303.1 219870928 7278224 721979..722707 1 NC_011852.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 722707 truC 7278224 truC Haemophilus parasuis SH0165 tRNA pseudouridine synthase C YP_002475303.1 721979 D 557723 CDS YP_002475304.1 219870929 7278225 722725..722880 1 NC_011852.1 COG:S;COG3140; hypothetical protein 722880 7278225 HAPS_0710 Haemophilus parasuis SH0165 hypothetical protein YP_002475304.1 722725 D 557723 CDS YP_002475305.1 219870930 7278226 722881..723345 1 NC_011852.1 hypothetical protein 723345 7278226 HAPS_0711 Haemophilus parasuis SH0165 hypothetical protein YP_002475305.1 722881 D 557723 CDS YP_002475306.1 219870931 7278227 complement(723356..723652) 1 NC_011852.1 COG:S;COG2914; hypothetical protein 723652 7278227 HAPS_0712 Haemophilus parasuis SH0165 hypothetical protein YP_002475306.1 723356 R 557723 CDS YP_002475307.1 219870932 7278228 complement(723642..724076) 1 NC_011852.1 COG:I;COG2867; oligoketide cyclase/lipid transport protein 724076 7278228 HAPS_0713 Haemophilus parasuis SH0165 oligoketide cyclase/lipid transport protein YP_002475307.1 723642 R 557723 CDS YP_002475308.1 219870933 7278229 complement(724284..724787) 1 NC_011852.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 724787 ispF 7278229 ispF Haemophilus parasuis SH0165 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002475308.1 724284 R 557723 CDS YP_002475309.1 219870934 7278230 complement(724792..725472) 1 NC_011852.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 725472 ispD 7278230 ispD Haemophilus parasuis SH0165 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002475309.1 724792 R 557723 CDS YP_002475310.1 219870935 7278231 complement(725472..725753) 1 NC_011852.1 COG:D;COG2919; cell division protein FtsB 725753 ftsB 7278231 ftsB Haemophilus parasuis SH0165 cell division protein FtsB YP_002475310.1 725472 R 557723 CDS YP_002475311.1 219870936 7278232 725940..727550 1 NC_011852.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 727550 pckA 7278232 pckA Haemophilus parasuis SH0165 phosphoenolpyruvate carboxykinase YP_002475311.1 725940 D 557723 CDS YP_002475312.1 219870937 7278233 complement(727815..728645) 1 NC_011852.1 COG:S;COG3025; hypothetical protein 728645 7278233 HAPS_0718 Haemophilus parasuis SH0165 hypothetical protein YP_002475312.1 727815 R 557723 CDS YP_002475313.1 219870938 7278234 complement(728852..729481) 1 NC_011852.1 COG:T;COG3073; sigma-E factor negative regulatory protein 729481 rseA 7278234 rseA Haemophilus parasuis SH0165 sigma-E factor negative regulatory protein YP_002475313.1 728852 R 557723 CDS YP_002475314.1 219870939 7278235 complement(729509..730078) 1 NC_011852.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 730078 rpoE 7278235 rpoE Haemophilus parasuis SH0165 RNA polymerase sigma factor RpoE YP_002475314.1 729509 R 557723 CDS YP_002475315.1 219870940 7278236 complement(730071..730217) 1 NC_011852.1 hypothetical protein 730217 7278236 HAPS_0721 Haemophilus parasuis SH0165 hypothetical protein YP_002475315.1 730071 R 557723 CDS YP_002475316.1 219870941 7278237 730305..731852 1 NC_011852.1 COG:V;COG0286; type I restriction-modification system, M subunit 731852 hsdM 7278237 hsdM Haemophilus parasuis SH0165 type I restriction-modification system, M subunit YP_002475316.1 730305 D 557723 CDS YP_002475317.1 219870942 7278238 732128..733354 1 NC_011852.1 COG:V;COG0732; type I restriction enzyme specificity protein HsdS 733354 hsdS 7278238 hsdS Haemophilus parasuis SH0165 type I restriction enzyme specificity protein HsdS YP_002475317.1 732128 D 557723 CDS YP_002475318.1 219870943 7278239 733453..736521 1 NC_011852.1 COG:V;COG0610; type I site-specific restriction-modification system, R (restriction) subunit 736521 hsdR 7278239 hsdR Haemophilus parasuis SH0165 type I site-specific restriction-modification system, R (restriction) subunit YP_002475318.1 733453 D 557723 CDS YP_002475319.1 219870944 7278240 complement(736736..738253) 1 NC_011852.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 738253 lnt 7278240 lnt Haemophilus parasuis SH0165 apolipoprotein N-acyltransferase YP_002475319.1 736736 R 557723 CDS YP_002475320.1 219870945 7278241 complement(738250..739134) 1 NC_011852.1 COG:P;COG4535; magnesium and cobalt efflux protein 739134 corC 7278241 corC Haemophilus parasuis SH0165 magnesium and cobalt efflux protein YP_002475320.1 738250 R 557723 CDS YP_002475321.1 219870946 7278242 739286..739927 1 NC_011852.1 COG:S;COG3110; hypothetical protein 739927 7278242 HAPS_0727 Haemophilus parasuis SH0165 hypothetical protein YP_002475321.1 739286 D 557723 CDS YP_002475322.1 219870947 7278244 complement(740823..742013) 1 NC_011852.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 742013 dxr 7278244 dxr Haemophilus parasuis SH0165 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002475322.1 740823 R 557723 CDS YP_002475323.1 219870948 7278245 complement(742052..742282) 1 NC_011852.1 hypothetical protein 742282 7278245 HAPS_0730 Haemophilus parasuis SH0165 hypothetical protein YP_002475323.1 742052 R 557723 CDS YP_002475324.1 219870949 7278246 complement(742478..742708) 1 NC_011852.1 hypothetical protein 742708 7278246 HAPS_0731 Haemophilus parasuis SH0165 hypothetical protein YP_002475324.1 742478 R 557723 CDS YP_002475325.1 219870950 7278247 complement(742721..744928) 1 NC_011852.1 COG:TK;COG0317; GTP pyrophosphokinase 744928 relA 7278247 relA Haemophilus parasuis SH0165 GTP pyrophosphokinase YP_002475325.1 742721 R 557723 CDS YP_002475326.1 219870951 7278248 745202..746509 1 NC_011852.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 746509 hemA 7278248 hemA Haemophilus parasuis SH0165 glutamyl-tRNA reductase YP_002475326.1 745202 D 557723 CDS YP_002475327.1 219870952 7278249 746650..748164 1 NC_011852.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 748164 engA 7278249 engA Haemophilus parasuis SH0165 GTP-binding protein EngA YP_002475327.1 746650 D 557723 CDS YP_002475328.1 219870953 7278250 748177..749604 1 NC_011852.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 749604 rfaE 7278250 rfaE Haemophilus parasuis SH0165 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_002475328.1 748177 D 557723 CDS YP_002475329.1 219870954 7278251 749672..750610 1 NC_011852.1 COG:O;COG0760; peptidyl-prolyl cis-trans isomerase SurA 750610 surA 7278251 surA Haemophilus parasuis SH0165 peptidyl-prolyl cis-trans isomerase SurA YP_002475329.1 749672 D 557723 CDS YP_002475330.1 219870955 7278252 750709..751569 1 NC_011852.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 751569 ksgA 7278252 ksgA Haemophilus parasuis SH0165 dimethyladenosine transferase YP_002475330.1 750709 D 557723 CDS YP_002475331.1 219870956 7278254 complement(752203..753477) 1 NC_011852.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 753477 murA 7278254 murA Haemophilus parasuis SH0165 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002475331.1 752203 R 557723 CDS YP_002475332.1 219870957 7278255 complement(753501..753758) 1 NC_011852.1 COG:K;COG5007; morphology/transcription regulator BolA family protein 753758 bolA 7278255 bolA Haemophilus parasuis SH0165 morphology/transcription regulator BolA family protein YP_002475332.1 753501 R 557723 CDS YP_002475333.1 219870958 7278256 complement(753761..754099) 1 NC_011852.1 COG:R;COG3113; putative anti-sigma factor B antagonist 754099 rsbV 7278256 rsbV Haemophilus parasuis SH0165 putative anti-sigma factor B antagonist YP_002475333.1 753761 R 557723 CDS YP_002475334.1 219870959 7278257 complement(754107..754742) 1 NC_011852.1 COG:Q;COG2854; resistance to organic solvents ABC transporter auxiliary component 754742 7278257 HAPS_0742 Haemophilus parasuis SH0165 resistance to organic solvents ABC transporter auxiliary component YP_002475334.1 754107 R 557723 CDS YP_002475335.1 219870960 7278258 complement(754779..755288) 1 NC_011852.1 COG:Q;COG1463; resistance to organic solvents ABC transporter periplasmic component 755288 7278258 HAPS_0743 Haemophilus parasuis SH0165 resistance to organic solvents ABC transporter periplasmic component YP_002475335.1 754779 R 557723 CDS YP_002475336.1 219870961 7278259 complement(755361..756134) 1 NC_011852.1 COG:Q;COG0767; resistance to organic solvents ABC transporter permease 756134 7278259 HAPS_0744 Haemophilus parasuis SH0165 resistance to organic solvents ABC transporter permease YP_002475336.1 755361 R 557723 CDS YP_002475337.1 219870962 7278260 complement(756134..756934) 1 NC_011852.1 COG:Q;COG1127; ABC transporter ATP-binding protein 756934 7278260 HAPS_0745 Haemophilus parasuis SH0165 ABC transporter ATP-binding protein YP_002475337.1 756134 R 557723 CDS YP_002475338.1 219870963 7278261 complement(757128..757718) 1 NC_011852.1 COG:R;COG2823; hypothetical protein 757718 7278261 HAPS_0746 Haemophilus parasuis SH0165 hypothetical protein YP_002475338.1 757128 R 557723 CDS YP_002475339.1 219870964 7278262 complement(757739..758329) 1 NC_011852.1 COG:G;COG0279; putative phosphoheptose isomerase 758329 gmhA 7278262 gmhA Haemophilus parasuis SH0165 putative phosphoheptose isomerase YP_002475339.1 757739 R 557723 CDS YP_002475340.1 219870965 7278263 complement(758331..758675) 1 NC_011852.1 distantly related to archaeal holliday junction resolvase; COG:L;COG0792; hypothetical protein 758675 7278263 HAPS_0748 Haemophilus parasuis SH0165 hypothetical protein YP_002475340.1 758331 R 557723 CDS YP_002475341.1 219870966 7278264 complement(758677..760413) 1 NC_011852.1 COG:R;COG3107; lipoprotein C/GS60 antigen 760413 lppC 7278264 lppC Haemophilus parasuis SH0165 lipoprotein C/GS60 antigen YP_002475341.1 758677 R 557723 CDS YP_002475342.1 219870967 7278265 760504..761364 1 NC_011852.1 COG:R;COG0313; putative methyltransferase 761364 7278265 HAPS_0750 Haemophilus parasuis SH0165 putative methyltransferase YP_002475342.1 760504 D 557723 CDS YP_002475343.1 219870968 7278266 761541..762026 1 NC_011852.1 COG:P;COG0783; ferritin and DNA-binding stress protein 762026 dps 7278266 dps Haemophilus parasuis SH0165 ferritin and DNA-binding stress protein YP_002475343.1 761541 D 557723 CDS YP_002475344.1 219870969 7278267 complement(762222..763061) 1 NC_011852.1 COG:S;COG1801; hypothetical protein 763061 7278267 HAPS_0752 Haemophilus parasuis SH0165 hypothetical protein YP_002475344.1 762222 R 557723 CDS YP_002475345.1 219870970 7278268 complement(763157..765733) 1 NC_011852.1 putative pertactin family virulence factor, outer membrane autotransporter/Type V secretory pathway, adhesin AidA 765733 aidA 7278268 aidA Haemophilus parasuis SH0165 putative pertactin family virulence factor, outer membrane autotransporter/Type V secretory pathway, adhesin AidA YP_002475345.1 763157 R 557723 CDS YP_002475346.1 219870971 7278269 765959..767326 1 NC_011852.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 767326 purB 7278269 purB Haemophilus parasuis SH0165 adenylosuccinate lyase YP_002475346.1 765959 D 557723 CDS YP_002475347.1 219870972 7278270 767477..768424 1 NC_011852.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 768424 ldhA 7278270 ldhA Haemophilus parasuis SH0165 glycerate dehydrogenase YP_002475347.1 767477 D 557723 CDS YP_002475348.1 219870973 7278271 768449..768991 1 NC_011852.1 COG:P;COG2032; superoxide dismutase 768991 sodC 7278271 sodC Haemophilus parasuis SH0165 superoxide dismutase YP_002475348.1 768449 D 557723 CDS YP_002475349.1 219870974 7278272 769077..770258 1 NC_011852.1 COG:M;COG4591; lipoprotein releasing system transmembrane protein/ABC-type transport system, involved in lipoprotein release, permease 770258 lolC 7278272 lolC Haemophilus parasuis SH0165 lipoprotein releasing system transmembrane protein/ABC-type transport system, involved in lipoprotein release, permease YP_002475349.1 769077 D 557723 CDS YP_002475350.1 219870975 7278273 770251..770907 1 NC_011852.1 COG:S;COG2364; hypothetical protein 770907 7278273 HAPS_0758 Haemophilus parasuis SH0165 hypothetical protein YP_002475350.1 770251 D 557723 CDS YP_002475351.1 219870976 7278275 complement(771662..772174) 1 NC_011852.1 putative phage associated protein 772174 7278275 HAPS_0760 Haemophilus parasuis SH0165 putative phage associated protein YP_002475351.1 771662 R 557723 CDS YP_002475352.1 219870977 7278277 complement(773951..775042) 1 NC_011852.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 775042 engD 7278277 engD Haemophilus parasuis SH0165 GTP-dependent nucleic acid-binding protein EngD YP_002475352.1 773951 R 557723 CDS YP_002475353.1 219870978 7278278 complement(775101..775685) 1 NC_011852.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 775685 pth 7278278 pth Haemophilus parasuis SH0165 peptidyl-tRNA hydrolase YP_002475353.1 775101 R 557723 CDS YP_002475354.1 219870979 7278279 776119..776514 1 NC_011852.1 COG:NU;COG3121; fimbrial assembly chaperone 776514 fimB 7278279 fimB Haemophilus parasuis SH0165 fimbrial assembly chaperone YP_002475354.1 776119 D 557723 CDS YP_002475355.1 219870980 7278281 776801..776968 1 NC_011852.1 hypothetical protein 776968 7278281 HAPS_0766 Haemophilus parasuis SH0165 hypothetical protein YP_002475355.1 776801 D 557723 CDS YP_002475356.1 219870981 7278283 complement(777648..779483) 1 NC_011852.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 779483 ilvD 7278283 ilvD Haemophilus parasuis SH0165 dihydroxy-acid dehydratase YP_002475356.1 777648 R 557723 CDS YP_002475357.1 219870982 7278284 779505..779690 1 NC_011852.1 hypothetical protein 779690 7278284 HAPS_0769 Haemophilus parasuis SH0165 hypothetical protein YP_002475357.1 779505 D 557723 CDS YP_002475358.1 219870983 7278287 complement(781598..781756) 1 NC_011852.1 hypothetical protein 781756 7278287 HAPS_0772 Haemophilus parasuis SH0165 hypothetical protein YP_002475358.1 781598 R 557723 CDS YP_002475359.1 219870984 7278288 complement(781991..782299) 1 NC_011852.1 COG:S;COG3514; hypothetical protein 782299 7278288 HAPS_0773 Haemophilus parasuis SH0165 hypothetical protein YP_002475359.1 781991 R 557723 CDS YP_002475360.1 219870985 7278289 complement(782274..782552) 1 NC_011852.1 COG:S;COG2929; hypothetical protein 782552 7278289 HAPS_0774 Haemophilus parasuis SH0165 hypothetical protein YP_002475360.1 782274 R 557723 CDS YP_002475361.1 219870986 7278290 complement(783275..785464) 1 NC_011852.1 COG:L;COG5519; putative prophage primase 785464 7278290 HAPS_0775 Haemophilus parasuis SH0165 putative prophage primase YP_002475361.1 783275 R 557723 CDS YP_002475362.1 219870987 7278292 complement(785837..786250) 1 NC_011852.1 phage small subunit terminase 786250 7278292 HAPS_0777 Haemophilus parasuis SH0165 phage small subunit terminase YP_002475362.1 785837 R 557723 CDS YP_002475363.1 219870988 7278293 complement(786238..786711) 1 NC_011852.1 hypothetical protein 786711 7278293 HAPS_0778 Haemophilus parasuis SH0165 hypothetical protein YP_002475363.1 786238 R 557723 CDS YP_002475364.1 219870989 7278294 complement(786987..787193) 1 NC_011852.1 hypothetical protein 787193 7278294 HAPS_0779 Haemophilus parasuis SH0165 hypothetical protein YP_002475364.1 786987 R 557723 CDS YP_002475365.1 219870990 7278295 complement(787184..787531) 1 NC_011852.1 hypothetical protein 787531 7278295 HAPS_0780 Haemophilus parasuis SH0165 hypothetical protein YP_002475365.1 787184 R 557723 CDS YP_002475366.1 219870991 7278296 complement(787556..787750) 1 NC_011852.1 COG:K;COG3311; phage transcriptional regulator 787750 7278296 HAPS_0781 Haemophilus parasuis SH0165 phage transcriptional regulator YP_002475366.1 787556 R 557723 CDS YP_002475367.1 219870992 7278297 complement(787955..788764) 1 NC_011852.1 hypothetical protein 788764 7278297 HAPS_0782 Haemophilus parasuis SH0165 hypothetical protein YP_002475367.1 787955 R 557723 CDS YP_002475368.1 219870993 7278298 complement(788793..790040) 1 NC_011852.1 COG:L;COG0582; phage integrase 790040 intA 7278298 intA Haemophilus parasuis SH0165 phage integrase YP_002475368.1 788793 R 557723 CDS YP_002475369.1 219870994 7278300 complement(790480..791352) 1 NC_011852.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 791352 ubiA 7278300 ubiA Haemophilus parasuis SH0165 4-hydroxybenzoate octaprenyltransferase YP_002475369.1 790480 R 557723 CDS YP_002475370.1 219870995 7278301 complement(791355..792119) 1 NC_011852.1 COG:KG;COG1349; glycerol-3-phosphate regulon repressor 792119 glpR 7278301 glpR Haemophilus parasuis SH0165 glycerol-3-phosphate regulon repressor YP_002475370.1 791355 R 557723 CDS YP_002475371.1 219870996 7278302 complement(792196..793050) 1 NC_011852.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 793050 kdsA 7278302 kdsA Haemophilus parasuis SH0165 2-dehydro-3-deoxyphosphooctonate aldolase YP_002475371.1 792196 R 557723 CDS YP_002475372.1 219870997 7278303 complement(793258..793971) 1 NC_011852.1 COG:S;COG2912; hypothetical protein 793971 7278303 HAPS_0788 Haemophilus parasuis SH0165 hypothetical protein YP_002475372.1 793258 R 557723 CDS YP_002475373.1 219870998 7278304 complement(794112..794981) 1 NC_011852.1 COG:J;COG2890; HemK-like protein/protein-glutamine N-methyl transferase 794981 hemK 7278304 hemK Haemophilus parasuis SH0165 HemK-like protein/protein-glutamine N-methyl transferase YP_002475373.1 794112 R 557723 CDS YP_002475374.1 219870999 7278305 complement(794990..795733) 1 NC_011852.1 hypothetical protein 795733 7278305 HAPS_0790 Haemophilus parasuis SH0165 hypothetical protein YP_002475374.1 794990 R 557723 CDS YP_002475375.1 219871000 7278306 complement(795730..796617) 1 NC_011852.1 COG:L;COG0270; cytosine specific DNA methyltransferase (BSP6IM) 796617 bsp6IM 7278306 bsp6IM Haemophilus parasuis SH0165 cytosine specific DNA methyltransferase (BSP6IM) YP_002475375.1 795730 R 557723 CDS YP_002475376.1 219871001 7278307 complement(796702..797784) 1 NC_011852.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 797784 prfA 7278307 prfA Haemophilus parasuis SH0165 peptide chain release factor 1 YP_002475376.1 796702 R 557723 CDS YP_002475377.1 219871002 7278308 complement(797899..798171) 1 NC_011852.1 COG:L;COG0776; DNA-binding protein HU/transcriptional regulator 798171 hupA 7278308 hupA Haemophilus parasuis SH0165 DNA-binding protein HU/transcriptional regulator YP_002475377.1 797899 R 557723 CDS YP_002475378.1 219871003 7278309 complement(798303..798899) 1 NC_011852.1 COG:S;COG3068; hypothetical protein 798899 7278309 HAPS_0794 Haemophilus parasuis SH0165 hypothetical protein YP_002475378.1 798303 R 557723 CDS YP_002475379.1 219871004 7278310 complement(798909..799835) 1 NC_011852.1 COG:H;COG0407; uroporphyrinogen-III decarboxylase 799835 hemE 7278310 hemE Haemophilus parasuis SH0165 uroporphyrinogen-III decarboxylase YP_002475379.1 798909 R 557723 CDS YP_002475380.1 219871005 7278311 complement(800033..800836) 1 NC_011852.1 COG:G;COG0676; aldose 1-epimerase-like protein 800836 yeaD 7278311 yeaD Haemophilus parasuis SH0165 aldose 1-epimerase-like protein YP_002475380.1 800033 R 557723 CDS YP_002475381.1 219871006 7278312 complement(800890..802266) 1 NC_011852.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 802266 argH 7278312 argH Haemophilus parasuis SH0165 argininosuccinate lyase YP_002475381.1 800890 R 557723 CDS YP_002475382.1 219871007 7278313 802675..803787 1 NC_011852.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 803787 potA 7278313 potA Haemophilus parasuis SH0165 putrescine/spermidine ABC transporter ATPase YP_002475382.1 802675 D 557723 CDS YP_002475383.1 219871008 7278314 803774..804634 1 NC_011852.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 804634 potB 7278314 potB Haemophilus parasuis SH0165 spermidine/putrescine ABC transporter membrane protein YP_002475383.1 803774 D 557723 CDS YP_002475384.1 219871009 7278315 804634..805401 1 NC_011852.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 805401 potC 7278315 potC Haemophilus parasuis SH0165 spermidine/putrescine ABC transporter membrane protein YP_002475384.1 804634 D 557723 CDS YP_002475385.1 219871010 7278316 805697..806956 1 NC_011852.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 806956 hisS 7278316 hisS Haemophilus parasuis SH0165 histidyl-tRNA synthetase YP_002475385.1 805697 D 557723 CDS YP_002475386.1 219871011 7278317 806966..807586 1 NC_011852.1 COG:S;COG2976; hypothetical protein 807586 7278317 HAPS_0802 Haemophilus parasuis SH0165 hypothetical protein YP_002475386.1 806966 D 557723 CDS YP_002475387.1 219871012 7278318 807987..808805 1 NC_011852.1 COG:E;COG0345; pyrroline-5-carboxylate reductase 808805 proC 7278318 proC Haemophilus parasuis SH0165 pyrroline-5-carboxylate reductase YP_002475387.1 807987 D 557723 CDS YP_002475388.1 219871013 7278319 808802..809950 1 NC_011852.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 809950 hcaT 7278319 hcaT Haemophilus parasuis SH0165 putative 3-phenylpropionic acid transporter YP_002475388.1 808802 D 557723 CDS YP_002475389.1 219871014 7278321 complement(810702..811541) 1 NC_011852.1 COG:R;COG2961; protein involved in catabolism of external DNA 811541 7278321 HAPS_0806 Haemophilus parasuis SH0165 protein involved in catabolism of external DNA YP_002475389.1 810702 R 557723 CDS YP_002475390.1 219871015 7278322 811599..812165 1 NC_011852.1 COG:V;COG3023; N-acetyl-anhydromuranmyl-L-alanine amidase 812165 ampD 7278322 ampD Haemophilus parasuis SH0165 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002475390.1 811599 D 557723 CDS YP_002475391.1 219871016 7278323 complement(812158..813066) 1 NC_011852.1 COG:S;COG2431; putative membrane protein, surface protein 813066 7278323 HAPS_0808 Haemophilus parasuis SH0165 putative membrane protein, surface protein YP_002475391.1 812158 R 557723 CDS YP_002475392.1 219871017 7278324 813210..814280 1 NC_011852.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 814280 dinP 7278324 dinP Haemophilus parasuis SH0165 DNA polymerase IV YP_002475392.1 813210 D 557723 CDS YP_002475393.1 219871018 7278325 814386..815237 1 NC_011852.1 putative metalloprotease; heat shock protein HtpX 815237 htpX 7278325 htpX Haemophilus parasuis SH0165 heat shock protein HtpX YP_002475393.1 814386 D 557723 CDS YP_002475394.1 219871019 7278326 complement(815248..817095) 1 NC_011852.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 817095 uvrC 7278326 uvrC Haemophilus parasuis SH0165 excinuclease ABC subunit C YP_002475394.1 815248 R 557723 CDS YP_002475395.1 219871020 7278327 complement(817119..817667) 1 NC_011852.1 COG:I;COG0558; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 817667 pgsA 7278327 pgsA Haemophilus parasuis SH0165 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002475395.1 817119 R 557723 CDS YP_002475396.1 219871021 7278328 817817..818524 1 NC_011852.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 818524 modB 7278328 modB Haemophilus parasuis SH0165 molybdate ABC transporter permease YP_002475396.1 817817 D 557723 CDS YP_002475397.1 219871022 7278329 818524..819585 1 NC_011852.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 819585 modC 7278329 modC Haemophilus parasuis SH0165 molybdate transporter ATP-binding protein YP_002475397.1 818524 D 557723 CDS YP_002475398.1 219871023 7278330 819803..820423 1 NC_011852.1 COG:P;COG0605; manganese superoxide dismutase 820423 sodA 7278330 sodA Haemophilus parasuis SH0165 manganese superoxide dismutase YP_002475398.1 819803 D 557723 CDS YP_002475399.1 219871024 7278332 complement(822127..822273) 1 NC_011852.1 hypothetical protein 822273 7278332 HAPS_0817 Haemophilus parasuis SH0165 hypothetical protein YP_002475399.1 822127 R 557723 CDS YP_002475400.1 219871025 7278333 complement(822324..822521) 1 NC_011852.1 hypothetical protein 822521 7278333 HAPS_0818 Haemophilus parasuis SH0165 hypothetical protein YP_002475400.1 822324 R 557723 CDS YP_002475401.1 219871026 7278334 complement(822674..823024) 1 NC_011852.1 hypothetical protein 823024 7278334 HAPS_0819 Haemophilus parasuis SH0165 hypothetical protein YP_002475401.1 822674 R 557723 CDS YP_002475402.1 219871027 7278335 complement(823040..823813) 1 NC_011852.1 COG:S;COG3680; hypothetical protein 823813 7278335 HAPS_0820 Haemophilus parasuis SH0165 hypothetical protein YP_002475402.1 823040 R 557723 CDS YP_002475403.1 219871028 7278336 complement(823823..824251) 1 NC_011852.1 hypothetical protein 824251 7278336 HAPS_0821 Haemophilus parasuis SH0165 hypothetical protein YP_002475403.1 823823 R 557723 CDS YP_002475404.1 219871029 7278337 824376..824765 1 NC_011852.1 COG:K;COG1396; transcriptional regulator/helix-turn-helix domain-containing protein 824765 7278337 HAPS_0822 Haemophilus parasuis SH0165 transcriptional regulator/helix-turn-helix domain-containing protein YP_002475404.1 824376 D 557723 CDS YP_002475405.1 219871030 7278338 complement(824800..826017) 1 NC_011852.1 COG:L;COG0582; CP4-57 prophage, integrase 826017 intA 7278338 intA Haemophilus parasuis SH0165 CP4-57 prophage, integrase YP_002475405.1 824800 R 557723 CDS YP_002475406.1 219871031 7278341 826466..826585 1 NC_011852.1 hypothetical protein 826585 7278341 HAPS_0824 Haemophilus parasuis SH0165 hypothetical protein YP_002475406.1 826466 D 557723 CDS YP_002475407.1 219871032 7278340 827364..828008 1 NC_011852.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 828008 pyrE 7278340 pyrE Haemophilus parasuis SH0165 orotate phosphoribosyltransferase YP_002475407.1 827364 D 557723 CDS YP_002475408.1 219871033 7278342 complement(828462..829661) 1 NC_011852.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 829661 rho 7278342 rho Haemophilus parasuis SH0165 transcription termination factor Rho YP_002475408.1 828462 R 557723 CDS YP_002475409.1 219871034 7278343 829796..829906 1 NC_011852.1 hypothetical protein 829906 7278343 HAPS_0828 Haemophilus parasuis SH0165 hypothetical protein YP_002475409.1 829796 D 557723 CDS YP_002475410.1 219871035 7278344 829899..830267 1 NC_011852.1 COG:J;COG1188; heat shock-like protein 15 830267 hslR 7278344 hslR Haemophilus parasuis SH0165 heat shock-like protein 15 YP_002475410.1 829899 D 557723 CDS YP_002475411.1 219871036 7278345 830377..831246 1 NC_011852.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 831246 hslO 7278345 hslO Haemophilus parasuis SH0165 Hsp33-like chaperonin YP_002475411.1 830377 D 557723 CDS YP_002475412.1 219871037 7278346 831317..832087 1 NC_011852.1 COG:L;COG0847; DNA polymerase III subunit epsilon 832087 dnaQ 7278346 dnaQ Haemophilus parasuis SH0165 DNA polymerase III subunit epsilon YP_002475412.1 831317 D 557723 CDS YP_002475413.1 219871038 7278348 complement(832372..833826) 1 NC_011852.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 833826 gnd 7278348 gnd Haemophilus parasuis SH0165 6-phosphogluconate dehydrogenase YP_002475413.1 832372 R 557723 CDS YP_002475414.1 219871039 7278349 complement(834164..834682) 1 NC_011852.1 COG:L;COG1943; hypothetical protein 834682 7278349 HAPS_0834 Haemophilus parasuis SH0165 hypothetical protein YP_002475414.1 834164 R 557723 CDS YP_002475415.1 219871040 7278350 complement(834734..835093) 1 NC_011852.1 COG:S;COG3759; integral membrane protein 835093 7278350 HAPS_0835 Haemophilus parasuis SH0165 integral membrane protein YP_002475415.1 834734 R 557723 CDS YP_002475416.1 219871041 7278351 complement(835102..836121) 1 NC_011852.1 COG:S;COG4804; hypothetical protein 836121 7278351 HAPS_0836 Haemophilus parasuis SH0165 hypothetical protein YP_002475416.1 835102 R 557723 CDS YP_002475417.1 219871042 7278352 complement(836160..836858) 1 NC_011852.1 COG:G;COG0363; 6-phosphogluconolactonase 836858 devB 7278352 devB Haemophilus parasuis SH0165 6-phosphogluconolactonase YP_002475417.1 836160 R 557723 CDS YP_002475418.1 219871043 7278353 complement(836974..838458) 1 NC_011852.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 838458 zwf 7278353 zwf Haemophilus parasuis SH0165 glucose-6-phosphate 1-dehydrogenase YP_002475418.1 836974 R 557723 CDS YP_002475419.1 219871044 7278354 complement(838523..839335) 1 NC_011852.1 COG:P;COG1218; 3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase 839335 cysQ 7278354 cysQ Haemophilus parasuis SH0165 3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase YP_002475419.1 838523 R 557723 CDS YP_002475420.1 219871045 7278355 839917..840663 1 NC_011852.1 COG:J;COG1186; peptide chain release factor 2 840663 prfB 7278355 prfB Haemophilus parasuis SH0165 peptide chain release factor 2 YP_002475420.1 839917 D 557723 CDS YP_002475421.1 219871046 7278356 complement(840753..841586) 1 NC_011852.1 COG:QR;COG0500; hypothetical protein 841586 7278356 HAPS_0841 Haemophilus parasuis SH0165 hypothetical protein YP_002475421.1 840753 R 557723 CDS YP_002475422.1 219871047 7278357 complement(841838..842935) 1 NC_011852.1 COG:L;COG5433; ISAma3, family ISAs1 842935 7278357 HAPS_0842 Haemophilus parasuis SH0165 ISAma3, family ISAs1 YP_002475422.1 841838 R 557723 CDS YP_002475423.1 219871048 7278359 complement(843620..843961) 1 NC_011852.1 COG:L;COG1555; DNA uptake protein 843961 comEA 7278359 comEA Haemophilus parasuis SH0165 DNA uptake protein YP_002475423.1 843620 R 557723 CDS YP_002475424.1 219871049 7278360 844219..845484 1 NC_011852.1 COG:M;COG3061; opacity associated protein A 845484 oapA 7278360 oapA Haemophilus parasuis SH0165 opacity associated protein A YP_002475424.1 844219 D 557723 CDS YP_002475425.1 219871050 7278361 845544..845942 1 NC_011852.1 opacity associated protein B 845942 oapB 7278361 oapB Haemophilus parasuis SH0165 opacity associated protein B YP_002475425.1 845544 D 557723 CDS YP_002475426.1 219871051 7278362 845951..847003 1 NC_011852.1 COG:M;COG0859; ADP-heptose--LPS heptosyltransferase 847003 rfaF 7278362 rfaF Haemophilus parasuis SH0165 ADP-heptose--LPS heptosyltransferase YP_002475426.1 845951 D 557723 CDS YP_002475427.1 219871052 7278363 847099..847686 1 NC_011852.1 COG:I;COG1182; azoreductase/NAD(P)H dehydrogenase (quinone) 847686 acpD 7278363 acpD Haemophilus parasuis SH0165 azoreductase/NAD(P)H dehydrogenase (quinone) YP_002475427.1 847099 D 557723 CDS YP_002475428.1 219871053 7278364 847857..849515 1 NC_011852.1 COG:G;COG1109; phosphomannomutase 849515 manB 7278364 manB Haemophilus parasuis SH0165 phosphomannomutase YP_002475428.1 847857 D 557723 CDS YP_002475429.1 219871054 7278365 849646..850653 1 NC_011852.1 COG:J;COG0566; rRNA methyltransferase 850653 ftsJ 7278365 ftsJ Haemophilus parasuis SH0165 rRNA methyltransferase YP_002475429.1 849646 D 557723 CDS YP_002475430.1 219871055 7278366 850856..851839 1 NC_011852.1 COG:H;COG0142; octaprenyl-diphosphate synthase 851839 ispB 7278366 ispB Haemophilus parasuis SH0165 octaprenyl-diphosphate synthase YP_002475430.1 850856 D 557723 CDS YP_002475431.1 219871056 7278367 852048..852788 1 NC_011852.1 COG:S;COG1636; hypothetical protein 852788 7278367 HAPS_0852 Haemophilus parasuis SH0165 hypothetical protein YP_002475431.1 852048 D 557723 CDS YP_002475432.1 219871057 7278368 852883..853818 1 NC_011852.1 COG:I;COG0331; malonyl CoA-acyl carrier protein transacylase 853818 fabD 7278368 fabD Haemophilus parasuis SH0165 malonyl CoA-acyl carrier protein transacylase YP_002475432.1 852883 D 557723 CDS YP_002475433.1 219871058 7278369 853961..854686 1 NC_011852.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 854686 fabG 7278369 fabG Haemophilus parasuis SH0165 3-ketoacyl-ACP reductase YP_002475433.1 853961 D 557723 CDS YP_002475434.1 219871059 7278370 complement(854687..854800) 1 NC_011852.1 hypothetical protein 854800 7278370 HAPS_0855 Haemophilus parasuis SH0165 hypothetical protein YP_002475434.1 854687 R 557723 CDS YP_002475435.1 219871060 7277006 854802..856088 1 NC_011852.1 COG:E;COG1114; branched-chain amino acid permease 856088 brnQ 7277006 brnQ Haemophilus parasuis SH0165 branched-chain amino acid permease YP_002475435.1 854802 D 557723 CDS YP_002475436.1 219871061 7277008 856145..856969 1 NC_011852.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 856969 mutM 7277008 mutM Haemophilus parasuis SH0165 formamidopyrimidine-DNA glycosylase YP_002475436.1 856145 D 557723 CDS YP_002475437.1 219871062 7277010 complement(857594..857962) 1 NC_011852.1 COG:S;COG5566; bacteriophage transcriptional regulator 857962 7277010 HAPS_0859 Haemophilus parasuis SH0165 bacteriophage transcriptional regulator YP_002475437.1 857594 R 557723 CDS YP_002475438.1 219871063 7277011 complement(857964..858362) 1 NC_011852.1 COG:S;COG4382; Mu-like phage E16 protein 858362 7277011 HAPS_0860 Haemophilus parasuis SH0165 Mu-like phage E16 protein YP_002475438.1 857964 R 557723 CDS YP_002475439.1 219871064 7277013 complement(858525..858683) 1 NC_011852.1 hypothetical protein 858683 7277013 HAPS_0862 Haemophilus parasuis SH0165 hypothetical protein YP_002475439.1 858525 R 557723 CDS YP_002475440.1 219871065 7277014 complement(858683..858895) 1 NC_011852.1 hypothetical protein 858895 7277014 HAPS_0863 Haemophilus parasuis SH0165 hypothetical protein YP_002475440.1 858683 R 557723 CDS YP_002475441.1 219871066 7277015 complement(858892..859416) 1 NC_011852.1 COG:R;COG4396; host-nuclease inhibitor protein 859416 gam 7277015 gam Haemophilus parasuis SH0165 host-nuclease inhibitor protein YP_002475441.1 858892 R 557723 CDS YP_002475442.1 219871067 7277016 complement(859409..859627) 1 NC_011852.1 hypothetical protein 859627 7277016 HAPS_0865 Haemophilus parasuis SH0165 hypothetical protein YP_002475442.1 859409 R 557723 CDS YP_002475443.1 219871068 7277017 complement(859620..860774) 1 NC_011852.1 COG:U;COG3267; ExeA protein, phage-like protein 860774 exeA 7277017 exeA Haemophilus parasuis SH0165 ExeA protein, phage-like protein YP_002475443.1 859620 R 557723 CDS YP_002475444.1 219871069 7277018 complement(860817..862427) 1 NC_011852.1 putative phage associated protein 862427 7277018 HAPS_0867 Haemophilus parasuis SH0165 putative phage associated protein YP_002475444.1 860817 R 557723 CDS YP_002475445.1 219871070 7277019 complement(862630..863520) 1 NC_011852.1 putative phage associated protein 863520 7277019 HAPS_0868 Haemophilus parasuis SH0165 putative phage associated protein YP_002475445.1 862630 R 557723 CDS YP_002475446.1 219871071 7277020 complement(863549..863851) 1 NC_011852.1 putative phage-like DNA-binding protein 863851 7277020 HAPS_0869 Haemophilus parasuis SH0165 putative phage-like DNA-binding protein YP_002475446.1 863549 R 557723 CDS YP_002475447.1 219871072 7277021 complement(863848..863991) 1 NC_011852.1 hypothetical protein 863991 7277021 HAPS_0870 Haemophilus parasuis SH0165 hypothetical protein YP_002475447.1 863848 R 557723 CDS YP_002475448.1 219871073 7277022 864047..864295 1 NC_011852.1 hypothetical protein 864295 7277022 HAPS_0871 Haemophilus parasuis SH0165 hypothetical protein YP_002475448.1 864047 D 557723 CDS YP_002475449.1 219871074 7277023 complement(864488..864721) 1 NC_011852.1 putative phage associated protein 864721 7277023 HAPS_0872 Haemophilus parasuis SH0165 putative phage associated protein YP_002475449.1 864488 R 557723 CDS YP_002475450.1 219871075 7277024 864785..865084 1 NC_011852.1 hypothetical protein 865084 7277024 HAPS_0873 Haemophilus parasuis SH0165 hypothetical protein YP_002475450.1 864785 D 557723 CDS YP_002475451.1 219871076 7277025 865409..865639 1 NC_011852.1 hypothetical protein 865639 7277025 HAPS_0874 Haemophilus parasuis SH0165 hypothetical protein YP_002475451.1 865409 D 557723 CDS YP_002475452.1 219871077 7277026 865687..866658 1 NC_011852.1 phage protein 866658 7277026 HAPS_0875 Haemophilus parasuis SH0165 phage protein YP_002475452.1 865687 D 557723 CDS YP_002475453.1 219871078 7277027 866658..867836 1 NC_011852.1 putative phage-like membrane protein 867836 7277027 HAPS_0876 Haemophilus parasuis SH0165 putative phage-like membrane protein YP_002475453.1 866658 D 557723 CDS YP_002475454.1 219871079 7277028 867930..868451 1 NC_011852.1 COG:R;COG3926; hypothetical bacteriophage protein 868451 7277028 HAPS_0877 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475454.1 867930 D 557723 CDS YP_002475455.1 219871080 7277029 868552..868785 1 NC_011852.1 hypothetical protein 868785 7277029 HAPS_0878 Haemophilus parasuis SH0165 hypothetical protein YP_002475455.1 868552 D 557723 CDS YP_002475456.1 219871081 7277030 868782..869135 1 NC_011852.1 hypothetical protein 869135 7277030 HAPS_0879 Haemophilus parasuis SH0165 hypothetical protein YP_002475456.1 868782 D 557723 CDS YP_002475457.1 219871082 7277031 869160..869489 1 NC_011852.1 Mu-like phage gp25 869489 7277031 HAPS_0880 Haemophilus parasuis SH0165 Mu-like phage gp25 YP_002475457.1 869160 D 557723 CDS YP_002475458.1 219871083 7277032 869493..869783 1 NC_011852.1 hypothetical bacteriophage protein 869783 7277032 HAPS_0881 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475458.1 869493 D 557723 CDS YP_002475459.1 219871084 7277033 869817..870389 1 NC_011852.1 Mu-like phage gp27 870389 7277033 HAPS_0882 Haemophilus parasuis SH0165 Mu-like phage gp27 YP_002475459.1 869817 D 557723 CDS YP_002475460.1 219871085 7277034 870451..871686 1 NC_011852.1 COG:R;COG4373; prophage MuMc02, terminase, ATPase subunit /putative DNA packaging protein Gp17 871686 7277034 HAPS_0883 Haemophilus parasuis SH0165 prophage MuMc02, terminase, ATPase subunit /putative DNA packaging protein Gp17 YP_002475460.1 870451 D 557723 CDS YP_002475461.1 219871086 7277035 871690..873108 1 NC_011852.1 putative phage-like protein 873108 7277035 HAPS_0884 Haemophilus parasuis SH0165 putative phage-like protein YP_002475461.1 871690 D 557723 CDS YP_002475462.1 219871087 7277036 873105..874373 1 NC_011852.1 Mu GP30-like protein/phage putative head morphogenesis protein, SPP1 gp7 874373 7277036 HAPS_0885 Haemophilus parasuis SH0165 Mu GP30-like protein/phage putative head morphogenesis protein, SPP1 gp7 YP_002475462.1 873105 D 557723 CDS YP_002475463.1 219871088 7277037 874500..874955 1 NC_011852.1 bacteriophage Mu G-like protein/virion morphogenesis protein 874955 7277037 HAPS_0886 Haemophilus parasuis SH0165 bacteriophage Mu G-like protein/virion morphogenesis protein YP_002475463.1 874500 D 557723 CDS YP_002475464.1 219871089 7277038 875176..876282 1 NC_011852.1 hypothetical bacteriophage protein 876282 7277038 HAPS_0887 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475464.1 875176 D 557723 CDS YP_002475465.1 219871090 7277039 876318..877259 1 NC_011852.1 hypothetical bacteriophage protein 877259 7277039 HAPS_0888 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475465.1 876318 D 557723 CDS YP_002475466.1 219871091 7277040 877326..877769 1 NC_011852.1 Erp22-like protein 877769 7277040 HAPS_0889 Haemophilus parasuis SH0165 Erp22-like protein YP_002475466.1 877326 D 557723 CDS YP_002475467.1 219871092 7277041 877772..878209 1 NC_011852.1 hypothetical bacteriophage protein 878209 7277041 HAPS_0890 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475467.1 877772 D 557723 CDS YP_002475468.1 219871093 7277042 878209..878709 1 NC_011852.1 hypothetical bacteriophage protein 878709 7277042 HAPS_0891 Haemophilus parasuis SH0165 hypothetical bacteriophage protein YP_002475468.1 878209 D 557723 CDS YP_002475469.1 219871094 7277043 878719..880113 1 NC_011852.1 COG:R;COG3497; bacteriophage tail sheath protein 880113 7277043 HAPS_0892 Haemophilus parasuis SH0165 bacteriophage tail sheath protein YP_002475469.1 878719 D 557723 CDS YP_002475470.1 219871095 7277044 880113..880631 1 NC_011852.1 COG:R;COG3498; tail core-like protein 880631 7277044 HAPS_0893 Haemophilus parasuis SH0165 tail core-like protein YP_002475470.1 880113 D 557723 CDS YP_002475471.1 219871096 7277045 881196..881540 1 NC_011852.1 putative phage anti-repressor protein 881540 7277045 HAPS_0894 Haemophilus parasuis SH0165 putative phage anti-repressor protein YP_002475471.1 881196 D 557723 CDS YP_002475472.1 219871097 7277046 881545..881805 1 NC_011852.1 hypothetical protein 881805 7277046 HAPS_0895 Haemophilus parasuis SH0165 hypothetical protein YP_002475472.1 881545 D 557723 CDS YP_002475473.1 219871098 7277047 881885..882172 1 NC_011852.1 hypothetical protein 882172 7277047 HAPS_0896 Haemophilus parasuis SH0165 hypothetical protein YP_002475473.1 881885 D 557723 CDS YP_002475474.1 219871099 7277048 882147..882302 1 NC_011852.1 hypothetical protein 882302 7277048 HAPS_0897 Haemophilus parasuis SH0165 hypothetical protein YP_002475474.1 882147 D 557723 CDS YP_002475475.1 219871100 7277049 complement(882287..882571) 1 NC_011852.1 hypothetical protein 882571 7277049 HAPS_0898 Haemophilus parasuis SH0165 hypothetical protein YP_002475475.1 882287 R 557723 CDS YP_002475476.1 219871101 7277050 882615..885293 1 NC_011852.1 putative bacteriophage tail protein/phage tail tape measure protein, TP901 family 885293 7277050 HAPS_0899 Haemophilus parasuis SH0165 putative bacteriophage tail protein/phage tail tape measure protein, TP901 family YP_002475476.1 882615 D 557723 CDS YP_002475477.1 219871102 7277051 885293..886234 1 NC_011852.1 putative bacteriophage V tail protein 886234 7277051 HAPS_0900 Haemophilus parasuis SH0165 putative bacteriophage V tail protein YP_002475477.1 885293 D 557723 CDS YP_002475478.1 219871103 7277052 886227..886445 1 NC_011852.1 phage tail fiber-like protein 886445 7277052 HAPS_0901 Haemophilus parasuis SH0165 phage tail fiber-like protein YP_002475478.1 886227 D 557723 CDS YP_002475479.1 219871104 7277053 886449..887501 1 NC_011852.1 COG:R;COG3500; putative bacteriophage regulatory protein 887501 7277053 HAPS_0902 Haemophilus parasuis SH0165 putative bacteriophage regulatory protein YP_002475479.1 886449 D 557723 CDS YP_002475480.1 219871105 7277054 887516..888100 1 NC_011852.1 COG:R;COG4540; putative bacteriophage baseplate protein 888100 7277054 HAPS_0903 Haemophilus parasuis SH0165 putative bacteriophage baseplate protein YP_002475480.1 887516 D 557723 CDS YP_002475481.1 219871106 7277055 888158..888526 1 NC_011852.1 COG:R;COG3628; phage baseplate-like protein 888526 7277055 HAPS_0904 Haemophilus parasuis SH0165 phage baseplate-like protein YP_002475481.1 888158 D 557723 CDS YP_002475482.1 219871107 7277056 888513..889628 1 NC_011852.1 COG:R;COG3948; phage baseplate-like protein 889628 7277056 HAPS_0905 Haemophilus parasuis SH0165 phage baseplate-like protein YP_002475482.1 888513 D 557723 CDS YP_002475483.1 219871108 7277057 889621..890187 1 NC_011852.1 putative bacteriophage tail fiber protein 890187 7277057 HAPS_0906 Haemophilus parasuis SH0165 putative bacteriophage tail fiber protein YP_002475483.1 889621 D 557723 CDS YP_002475484.1 219871109 7277058 890211..892127 1 NC_011852.1 putative phage-like tail fiber protein 892127 7277058 HAPS_0907 Haemophilus parasuis SH0165 putative phage-like tail fiber protein YP_002475484.1 890211 D 557723 CDS YP_002475485.1 219871110 7277059 892137..892703 1 NC_011852.1 putative tail fiber assembly protein 892703 7277059 HAPS_0908 Haemophilus parasuis SH0165 putative tail fiber assembly protein YP_002475485.1 892137 D 557723 CDS YP_002475486.1 219871111 7277060 892696..893175 1 NC_011852.1 enoyl-CoA hydratase/carnithine racemase-like protein 893175 7277060 HAPS_0909 Haemophilus parasuis SH0165 enoyl-CoA hydratase/carnithine racemase-like protein YP_002475486.1 892696 D 557723 CDS YP_002475487.1 219871112 7277061 893489..896413 1 NC_011852.1 phage-like protein, tail component 896413 7277061 HAPS_0910 Haemophilus parasuis SH0165 phage-like protein, tail component YP_002475487.1 893489 D 557723 CDS YP_002475488.1 219871113 7277062 896442..897233 1 NC_011852.1 antimicrobial peptide ABC transporter ATPase 897233 7277062 HAPS_0911 Haemophilus parasuis SH0165 antimicrobial peptide ABC transporter ATPase YP_002475488.1 896442 D 557723 CDS YP_002475489.1 219871114 7277064 complement(897573..898529) 1 NC_011852.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 898529 znuA 7277064 znuA Haemophilus parasuis SH0165 high-affinity zinc transporter periplasmic protein YP_002475489.1 897573 R 557723 CDS YP_002475490.1 219871115 7277065 complement(898667..900034) 1 NC_011852.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 900034 pssA 7277065 pssA Haemophilus parasuis SH0165 phosphatidylserine synthase YP_002475490.1 898667 R 557723 CDS YP_002475491.1 219871116 7277066 900227..900442 1 NC_011852.1 hypothetical protein 900442 7277066 HAPS_0915 Haemophilus parasuis SH0165 hypothetical protein YP_002475491.1 900227 D 557723 CDS YP_002475492.1 219871117 7277067 complement(900540..903356) 1 NC_011852.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 903356 ileS 7277067 ileS Haemophilus parasuis SH0165 isoleucyl-tRNA synthetase YP_002475492.1 900540 R 557723 CDS YP_002475493.1 219871118 7277068 complement(903416..904078) 1 NC_011852.1 antitoxin/toxin system zeta toxin, signal recognition particle GTPase 904078 7277068 HAPS_0917 Haemophilus parasuis SH0165 antitoxin/toxin system zeta toxin, signal recognition particle GTPase YP_002475493.1 903416 R 557723 CDS YP_002475494.1 219871119 7277069 complement(904082..904363) 1 NC_011852.1 hypothetical protein 904363 7277069 HAPS_0918 Haemophilus parasuis SH0165 hypothetical protein YP_002475494.1 904082 R 557723 CDS YP_002475495.1 219871120 7277070 complement(904365..905342) 1 NC_011852.1 COG:H;COG0196; riboflavin biosynthesis protein 905342 ribF 7277070 ribF Haemophilus parasuis SH0165 riboflavin biosynthesis protein YP_002475495.1 904365 R 557723 CDS YP_002475496.1 219871121 7277071 905501..906535 1 NC_011852.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 906535 purM 7277071 purM Haemophilus parasuis SH0165 phosphoribosylaminoimidazole synthetase YP_002475496.1 905501 D 557723 CDS YP_002475497.1 219871122 7277072 complement(906890..908578) 1 NC_011852.1 hypothetical protein 908578 7277072 HAPS_0921 Haemophilus parasuis SH0165 hypothetical protein YP_002475497.1 906890 R 557723 CDS YP_002475498.1 219871123 7277073 complement(908643..908810) 1 NC_011852.1 hypothetical protein 908810 7277073 HAPS_0922 Haemophilus parasuis SH0165 hypothetical protein YP_002475498.1 908643 R 557723 CDS YP_002475499.1 219871124 7277074 complement(908983..909573) 1 NC_011852.1 hypothetical protein 909573 7277074 HAPS_0923 Haemophilus parasuis SH0165 hypothetical protein YP_002475499.1 908983 R 557723 CDS YP_002475500.1 219871125 7277075 909702..910673 1 NC_011852.1 COG:L;COG3547; ISNme5, family110 910673 7277075 HAPS_0924 Haemophilus parasuis SH0165 ISNme5, family110 YP_002475500.1 909702 D 557723 CDS YP_002475501.1 219871126 7277221 complement(910664..910786) 1 NC_011852.1 hypothetical protein 910786 7277221 HAPS_0925 Haemophilus parasuis SH0165 hypothetical protein YP_002475501.1 910664 R 557723 CDS YP_002475502.1 219871127 7277799 complement(910945..911724) 1 NC_011852.1 COG:R;COG4105; DNA uptake lipoprotein, TPR repeat-containing protein 911724 7277799 HAPS_0926 Haemophilus parasuis SH0165 DNA uptake lipoprotein, TPR repeat-containing protein YP_002475502.1 910945 R 557723 CDS YP_002475503.1 219871128 7277800 911861..912838 1 NC_011852.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 912838 rluD 7277800 rluD Haemophilus parasuis SH0165 23S rRNA pseudouridine synthase D YP_002475503.1 911861 D 557723 CDS YP_002475504.1 219871129 7277802 complement(913158..913469) 1 NC_011852.1 COG:T;COG0271; stress-induced morphogen 913469 bolA 7277802 bolA Haemophilus parasuis SH0165 stress-induced morphogen YP_002475504.1 913158 R 557723 CDS YP_002475505.1 219871130 7277803 913553..914140 1 NC_011852.1 COG:M;COG3056; pyruvate formate lyase-activating enzyme 1 lipoprotein 914140 pflA 7277803 pflA Haemophilus parasuis SH0165 pyruvate formate lyase-activating enzyme 1 lipoprotein YP_002475505.1 913553 D 557723 CDS YP_002475506.1 219871131 7277804 914377..915111 1 NC_011852.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 915111 7277804 HAPS_0931 Haemophilus parasuis SH0165 16S ribosomal RNA methyltransferase RsmE YP_002475506.1 914377 D 557723 CDS YP_002475507.1 219871132 7277805 915112..915669 1 NC_011852.1 COG:K;COG1678; hypothetical protein 915669 7277805 HAPS_0932 Haemophilus parasuis SH0165 hypothetical protein YP_002475507.1 915112 D 557723 CDS YP_002475508.1 219871133 7277806 915669..916085 1 NC_011852.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 916085 rusA 7277806 rusA Haemophilus parasuis SH0165 Holliday junction resolvase-like protein YP_002475508.1 915669 D 557723 CDS YP_002475509.1 219871134 7277807 complement(916104..917414) 1 NC_011852.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 917414 dgt 7277807 dgt Haemophilus parasuis SH0165 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_002475509.1 916104 R 557723 CDS YP_002475510.1 219871135 7277808 917496..918806 1 NC_011852.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 918806 rumA 7277808 rumA Haemophilus parasuis SH0165 23S rRNA 5-methyluridine methyltransferase YP_002475510.1 917496 D 557723 CDS YP_002475511.1 219871136 7277809 919085..920680 1 NC_011852.1 COG:E;COG0747; periplasmic dipeptide transport protein DppA 920680 dppA 7277809 dppA Haemophilus parasuis SH0165 periplasmic dipeptide transport protein DppA YP_002475511.1 919085 D 557723 CDS YP_002475512.1 219871137 7277810 920774..921778 1 NC_011852.1 COG:EP;COG0601; dipeptide transport system permease DppB 921778 dppB 7277810 dppB Haemophilus parasuis SH0165 dipeptide transport system permease DppB YP_002475512.1 920774 D 557723 CDS YP_002475513.1 219871138 7277811 921807..922700 1 NC_011852.1 COG:EP;COG1173; dipeptide transport system permease DppC 922700 dppC 7277811 dppC Haemophilus parasuis SH0165 dipeptide transport system permease DppC YP_002475513.1 921807 D 557723 CDS YP_002475514.1 219871139 7277812 922711..923694 1 NC_011852.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 923694 dppD 7277812 dppD Haemophilus parasuis SH0165 dipeptide transporter ATP-binding subunit YP_002475514.1 922711 D 557723 CDS YP_002475515.1 219871140 7277813 923709..924689 1 NC_011852.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 924689 dppF 7277813 dppF Haemophilus parasuis SH0165 dipeptide transporter ATP-binding subunit YP_002475515.1 923709 D 557723 CDS YP_002475516.1 219871141 7277814 complement(924741..925319) 1 NC_011852.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 925319 ruvC 7277814 ruvC Haemophilus parasuis SH0165 Holliday junction resolvase YP_002475516.1 924741 R 557723 CDS YP_002475517.1 219871142 7277815 complement(925393..925881) 1 NC_011852.1 excinuclease ABC subunit A 925881 uvrA 7277815 uvrA Haemophilus parasuis SH0165 excinuclease ABC subunit A YP_002475517.1 925393 R 557723 CDS YP_002475518.1 219871143 7277816 complement(925999..926739) 1 NC_011852.1 COG:S;COG0217; hypothetical protein 926739 aspS 7277816 aspS Haemophilus parasuis SH0165 hypothetical protein YP_002475518.1 925999 R 557723 CDS YP_002475519.1 219871144 7277817 complement(926878..927327) 1 NC_011852.1 COG:LR;COG0494; dATP pyrophosphohydrolase 927327 ntpA 7277817 ntpA Haemophilus parasuis SH0165 dATP pyrophosphohydrolase YP_002475519.1 926878 R 557723 CDS YP_002475520.1 219871145 7277818 927733..928371 1 NC_011852.1 hypothetical protein 928371 7277818 HAPS_0945 Haemophilus parasuis SH0165 hypothetical protein YP_002475520.1 927733 D 557723 CDS YP_002475521.1 219871146 7277819 928597..929376 1 NC_011852.1 COG:H;COG0294; dihydropteroate synthase 929376 folP 7277819 folP Haemophilus parasuis SH0165 dihydropteroate synthase YP_002475521.1 928597 D 557723 CDS YP_002475522.1 219871147 7277820 929391..929738 1 NC_011852.1 COG:P;COG1393; arsenate reductase 929738 arsC 7277820 arsC Haemophilus parasuis SH0165 arsenate reductase YP_002475522.1 929391 D 557723 CDS YP_002475523.1 219871148 7277821 929824..930444 1 NC_011852.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 930444 coaE 7277821 coaE Haemophilus parasuis SH0165 dephospho-CoA kinase YP_002475523.1 929824 D 557723 CDS YP_002475524.1 219871149 7277822 930448..930642 1 NC_011852.1 COG:S;COG3024; putative zinc-binding protein 930642 yacG 7277822 yacG Haemophilus parasuis SH0165 putative zinc-binding protein YP_002475524.1 930448 D 557723 CDS YP_002475525.1 219871150 7277823 complement(930639..931661) 1 NC_011852.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 931661 holA 7277823 holA Haemophilus parasuis SH0165 DNA polymerase III subunit delta YP_002475525.1 930639 R 557723 CDS YP_002475526.1 219871151 7277824 complement(931666..932160) 1 NC_011852.1 COG:M;COG2980; rare lipoprotein B 932160 rlpB 7277824 rlpB Haemophilus parasuis SH0165 rare lipoprotein B YP_002475526.1 931666 R 557723 CDS YP_002475527.1 219871152 7277825 complement(932243..934831) 1 NC_011852.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 934831 leuS 7277825 leuS Haemophilus parasuis SH0165 leucyl-tRNA synthetase YP_002475527.1 932243 R 557723 CDS YP_002475528.1 219871153 7277826 935071..935346 1 NC_011852.1 COG:K;COG1396; transcriptional regulator 935346 7277826 HAPS_0953 Haemophilus parasuis SH0165 transcriptional regulator YP_002475528.1 935071 D 557723 CDS YP_002475529.1 219871154 7277827 935536..937467 1 NC_011852.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 937467 thrS 7277827 thrS Haemophilus parasuis SH0165 threonyl-tRNA synthetase YP_002475529.1 935536 D 557723 CDS YP_002475530.1 219871155 7277828 937712..937867 1 NC_011852.1 hypothetical protein 937867 7277828 HAPS_0955 Haemophilus parasuis SH0165 hypothetical protein YP_002475530.1 937712 D 557723 CDS YP_002475531.1 219871156 7277830 complement(941857..943248) 1 NC_011852.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 943248 7277830 HAPS_0957 Haemophilus parasuis SH0165 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002475531.1 941857 R 557723 CDS YP_002475532.1 219871157 7277831 complement(943439..943942) 1 NC_011852.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 943942 crr 7277831 crr Haemophilus parasuis SH0165 PTS system glucose-specific transporter YP_002475532.1 943439 R 557723 CDS YP_002475533.1 219871158 7277832 complement(944016..945737) 1 NC_011852.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 945737 ptsI 7277832 ptsI Haemophilus parasuis SH0165 phosphoenolpyruvate-protein phosphotransferase YP_002475533.1 944016 R 557723 CDS YP_002475534.1 219871159 7277833 complement(945833..946090) 1 NC_011852.1 COG:G;COG1925; phosphotransferase system, phosphocarrier protein HPr 946090 ptsH 7277833 ptsH Haemophilus parasuis SH0165 phosphotransferase system, phosphocarrier protein HPr YP_002475534.1 945833 R 557723 CDS YP_002475535.1 219871160 7277834 946395..947510 1 NC_011852.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 947510 asd 7277834 asd Haemophilus parasuis SH0165 aspartate-semialdehyde dehydrogenase YP_002475535.1 946395 D 557723 CDS YP_002475536.1 219871161 7277835 complement(947540..947680) 1 NC_011852.1 hypothetical protein 947680 7277835 HAPS_0962 Haemophilus parasuis SH0165 hypothetical protein YP_002475536.1 947540 R 557723 CDS YP_002475537.1 219871162 7277836 947885..949492 1 NC_011852.1 hypothetical protein 949492 7277836 HAPS_0963 Haemophilus parasuis SH0165 hypothetical protein YP_002475537.1 947885 D 557723 CDS YP_002475538.1 219871163 7277838 950343..951506 1 NC_011852.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 951506 lpxB 7277838 lpxB Haemophilus parasuis SH0165 lipid-A-disaccharide synthase YP_002475538.1 950343 D 557723 CDS YP_002475539.1 219871164 7277839 complement(951539..952510) 1 NC_011852.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 952510 secF 7277839 secF Haemophilus parasuis SH0165 preprotein translocase subunit SecF YP_002475539.1 951539 R 557723 CDS YP_002475540.1 219871165 7277840 complement(952521..954332) 1 NC_011852.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 954332 secD 7277840 secD Haemophilus parasuis SH0165 preprotein translocase subunit SecD YP_002475540.1 952521 R 557723 CDS YP_002475541.1 219871166 7277841 complement(954394..954687) 1 NC_011852.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 954687 yajC 7277841 yajC Haemophilus parasuis SH0165 preprotein translocase subunit YajC YP_002475541.1 954394 R 557723 CDS YP_002475542.1 219871167 7277842 954893..955453 1 NC_011852.1 COG:R;COG3054; putative transcriptional regulator 955453 7277842 HAPS_0969 Haemophilus parasuis SH0165 putative transcriptional regulator YP_002475542.1 954893 D 557723 CDS YP_002475543.1 219871168 7277843 complement(955541..956872) 1 NC_011852.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 956872 argG 7277843 argG Haemophilus parasuis SH0165 argininosuccinate synthase YP_002475543.1 955541 R 557723 CDS YP_002475544.1 219871169 7277844 complement(957062..957745) 1 NC_011852.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 957745 gpmA 7277844 gpmA Haemophilus parasuis SH0165 phosphoglyceromutase YP_002475544.1 957062 R 557723 CDS YP_002475545.1 219871170 7277845 complement(957905..958672) 1 NC_011852.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 958672 kdsB 7277845 kdsB Haemophilus parasuis SH0165 3-deoxy-manno-octulosonate cytidylyltransferase YP_002475545.1 957905 R 557723 CDS YP_002475546.1 219871171 7277846 complement(958681..959247) 1 NC_011852.1 COG:S;COG3101; hypothetical protein 959247 7277846 HAPS_0973 Haemophilus parasuis SH0165 hypothetical protein YP_002475546.1 958681 R 557723 CDS YP_002475547.1 219871172 7277847 complement(959256..959819) 1 NC_011852.1 COG:C;COG0778; nitroreductase 959819 7277847 HAPS_0974 Haemophilus parasuis SH0165 nitroreductase YP_002475547.1 959256 R 557723 CDS YP_002475548.1 219871173 7277848 960216..962222 1 NC_011852.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 962222 tktA 7277848 tktA Haemophilus parasuis SH0165 transketolase YP_002475548.1 960216 D 557723 CDS YP_002475549.1 219871174 7277849 962296..963336 1 NC_011852.1 COG:M;COG0859; ADP-heptose--lipooligosaccharide heptosyltransferase III/heptosyltransferase-like protein 963336 waaQ 7277849 waaQ Haemophilus parasuis SH0165 ADP-heptose--lipooligosaccharide heptosyltransferase III/heptosyltransferase-like protein YP_002475549.1 962296 D 557723 CDS YP_002475550.1 219871175 7277850 963441..963869 1 NC_011852.1 COG:S;COG3787; hypothetical protein 963869 7277850 HAPS_0977 Haemophilus parasuis SH0165 hypothetical protein YP_002475550.1 963441 D 557723 CDS YP_002475551.1 219871176 7277851 963987..964991 1 NC_011852.1 COG:M;COG1088; dTDP-glucose 4,6-dehydratase 964991 rfbB 7277851 rfbB Haemophilus parasuis SH0165 dTDP-glucose 4,6-dehydratase YP_002475551.1 963987 D 557723 CDS YP_002475552.1 219871177 7277852 complement(965135..966013) 1 NC_011852.1 COG:R;COG1090; hypothetical protein 966013 7277852 HAPS_0979 Haemophilus parasuis SH0165 hypothetical protein YP_002475552.1 965135 R 557723 CDS YP_002475553.1 219871178 7277853 complement(966013..966474) 1 NC_011852.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 966474 argR 7277853 argR Haemophilus parasuis SH0165 arginine repressor YP_002475553.1 966013 R 557723 CDS YP_002475554.1 219871179 7277854 966676..967620 1 NC_011852.1 oxidizes malate to oxaloacetate; malate dehydrogenase 967620 mdh 7277854 mdh Haemophilus parasuis SH0165 malate dehydrogenase YP_002475554.1 966676 D 557723 CDS YP_002475555.1 219871180 7277855 967709..968557 1 NC_011852.1 COG:O;COG3118; thioredoxin-like protein 968557 7277855 HAPS_0982 Haemophilus parasuis SH0165 thioredoxin-like protein YP_002475555.1 967709 D 557723 CDS YP_002475556.1 219871181 7277856 968596..969546 1 NC_011852.1 COG:O;COG0492; thioredoxin reductase 969546 trxB 7277856 trxB Haemophilus parasuis SH0165 thioredoxin reductase YP_002475556.1 968596 D 557723 CDS YP_002475557.1 219871182 7277857 complement(969758..970516) 1 NC_011852.1 COG:M;COG0463; UDP-glucose-- lipooligosaccharideglucosyltransferase involved in cell wall biogenesis 970516 igtF 7277857 igtF Haemophilus parasuis SH0165 UDP-glucose-- lipooligosaccharideglucosyltransferase involved in cell wall biogenesis YP_002475557.1 969758 R 557723 CDS YP_002475558.1 219871183 7277858 970636..970950 1 NC_011852.1 COG:J;COG1534; 23S rRNA methyltransferase J 970950 rrmJ 7277858 rrmJ Haemophilus parasuis SH0165 23S rRNA methyltransferase J YP_002475558.1 970636 D 557723 CDS YP_002475559.1 219871184 7277864 979103..979294 1 NC_011852.1 hypothetical protein 979294 7277864 HAPS_0991 Haemophilus parasuis SH0165 hypothetical protein YP_002475559.1 979103 D 557723 CDS YP_002475560.1 219871185 7277866 979637..982108 1 NC_011852.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 982108 cyaA 7277866 cyaA Haemophilus parasuis SH0165 adenylate cyclase YP_002475560.1 979637 D 557723 CDS YP_002475561.1 219871186 7277867 982123..984057 1 NC_011852.1 COG:P;COG0475; glutathione-regulated potassium-efflux system protein 984057 kefB 7277867 kefB Haemophilus parasuis SH0165 glutathione-regulated potassium-efflux system protein YP_002475561.1 982123 D 557723 CDS YP_002475562.1 219871187 7277868 984212..985138 1 NC_011852.1 COG:L;COG2255; holliday junction DNA helicase B 985138 ruvB 7277868 ruvB Haemophilus parasuis SH0165 holliday junction DNA helicase B YP_002475562.1 984212 D 557723 CDS YP_002475563.1 219871188 7277869 985321..986958 1 NC_011852.1 COG:E;COG4166; oligopeptide permease ABC transporter membrane protein 986958 oppA 7277869 oppA Haemophilus parasuis SH0165 oligopeptide permease ABC transporter membrane protein YP_002475563.1 985321 D 557723 CDS YP_002475564.1 219871189 7277870 987053..987976 1 NC_011852.1 COG:EP;COG0601; oligopeptide ABC transporter periplasmic protein 987976 oppB 7277870 oppB Haemophilus parasuis SH0165 oligopeptide ABC transporter periplasmic protein YP_002475564.1 987053 D 557723 CDS YP_002475565.1 219871190 7277871 987987..988907 1 NC_011852.1 COG:EP;COG1173; oligopeptide ABC transporter permease 988907 oppC 7277871 oppC Haemophilus parasuis SH0165 oligopeptide ABC transporter permease YP_002475565.1 987987 D 557723 CDS YP_002475566.1 219871191 7277872 988919..990514 1 NC_011852.1 COG:R;COG4172; ABC transporter ATP-binding protein 990514 oppD 7277872 oppD Haemophilus parasuis SH0165 ABC transporter ATP-binding protein YP_002475566.1 988919 D 557723 CDS YP_002475567.1 219871192 7277873 complement(990582..992582) 1 NC_011852.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 992582 oppF 7277873 oppF Haemophilus parasuis SH0165 ABC transporter ATPase YP_002475567.1 990582 R 557723 CDS YP_002475568.1 219871193 7277874 992834..995551 1 NC_011852.1 COG:K;COG2909; ATP-dependent transcriptional regulator 995551 malT 7277874 malT Haemophilus parasuis SH0165 ATP-dependent transcriptional regulator YP_002475568.1 992834 D 557723 CDS YP_002475569.1 219871194 7277875 995757..996068 1 NC_011852.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 996068 7277875 HAPS_1002 Haemophilus parasuis SH0165 dsDNA-mimic protein YP_002475569.1 995757 D 557723 CDS YP_002475570.1 219871195 7277876 complement(996178..997428) 1 NC_011852.1 COG:H;COG3071; porphoryin biosynthesis protein HemY 997428 hemY 7277876 hemY Haemophilus parasuis SH0165 porphoryin biosynthesis protein HemY YP_002475570.1 996178 R 557723 CDS YP_002475571.1 219871196 7277877 complement(997439..998800) 1 NC_011852.1 COG:H;COG2959; putative uroporphyrin-III C-methyltransferase 998800 hemX 7277877 hemX Haemophilus parasuis SH0165 putative uroporphyrin-III C-methyltransferase YP_002475571.1 997439 R 557723 CDS YP_002475572.1 219871197 7277878 complement(998818..999576) 1 NC_011852.1 COG:H;COG1587; uroporphyrinogen-III synthase 999576 hemD 7277878 hemD Haemophilus parasuis SH0165 uroporphyrinogen-III synthase YP_002475572.1 998818 R 557723 CDS YP_002475573.1 219871198 7277879 complement(999578..1000507) 1 NC_011852.1 COG:H;COG0181; porphobilinogen deaminase 1000507 hemC 7277879 hemC Haemophilus parasuis SH0165 porphobilinogen deaminase YP_002475573.1 999578 R 557723 CDS YP_002475574.1 219871199 7277880 1000974..1002362 1 NC_011852.1 COG:E;COG1115; Na+/alanine symporter 1002362 alsT 7277880 alsT Haemophilus parasuis SH0165 Na+/alanine symporter YP_002475574.1 1000974 D 557723 CDS YP_002475575.1 219871200 7277222 complement(1002436..1003857) 1 NC_011852.1 COG:G;COG1263; PTS system sucrose-specific transporter subunit IIBC 1003857 ptsB 7277222 ptsB Haemophilus parasuis SH0165 PTS system sucrose-specific transporter subunit IIBC YP_002475575.1 1002436 R 557723 CDS YP_002475576.1 219871201 7277077 1004173..1007115 1 NC_011852.1 COG:O;COG1025; protease III 1007115 ptrA 7277077 ptrA Haemophilus parasuis SH0165 protease III YP_002475576.1 1004173 D 557723 CDS YP_002475577.1 219871202 7277078 complement(1007261..1007890) 1 NC_011852.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1007890 7277078 HAPS_1010 Haemophilus parasuis SH0165 hypothetical protein YP_002475577.1 1007261 R 557723 CDS YP_002475578.1 219871203 7277079 1008035..1010437 1 NC_011852.1 COG:O;COG0466; ATP-dependent protease LA 1010437 lon 7277079 lon Haemophilus parasuis SH0165 ATP-dependent protease LA YP_002475578.1 1008035 D 557723 CDS YP_002475579.1 219871204 7277080 complement(1010635..1011804) 1 NC_011852.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1011804 rumB 7277080 rumB Haemophilus parasuis SH0165 23S rRNA methyluridine methyltransferase YP_002475579.1 1010635 R 557723 CDS YP_002475580.1 219871205 7277081 complement(1011797..1012819) 1 NC_011852.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1012819 nagZ 7277081 nagZ Haemophilus parasuis SH0165 beta-hexosaminidase YP_002475580.1 1011797 R 557723 CDS YP_002475581.1 219871206 7277082 complement(1012841..1014640) 1 NC_011852.1 COG:KL;COG1199; putative ATP-dependent helicase 1014640 7277082 HAPS_1014 Haemophilus parasuis SH0165 putative ATP-dependent helicase YP_002475581.1 1012841 R 557723 CDS YP_002475582.1 219871207 7277083 complement(1014865..1015491) 1 NC_011852.1 COG:F;COG0035; uracil phosphoribosyltransferase 1015491 upp 7277083 upp Haemophilus parasuis SH0165 uracil phosphoribosyltransferase YP_002475582.1 1014865 R 557723 CDS YP_002475583.1 219871208 7277084 complement(1015553..1016362) 1 NC_011852.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 1016362 ilvY 7277084 ilvY Haemophilus parasuis SH0165 DNA-binding transcriptional regulator IlvY YP_002475583.1 1015553 R 557723 CDS YP_002475584.1 219871209 7277085 complement(1016447..1017481) 1 NC_011852.1 COG:M;COG0859; lipooligosaccharide D-glycero-D-manno-heptosyltransferase 1017481 lbgB 7277085 lbgB Haemophilus parasuis SH0165 lipooligosaccharide D-glycero-D-manno-heptosyltransferase YP_002475584.1 1016447 R 557723 CDS YP_002475585.1 219871210 7277086 complement(1017478..1017645) 1 NC_011852.1 hypothetical protein 1017645 7277086 HAPS_1018 Haemophilus parasuis SH0165 hypothetical protein YP_002475585.1 1017478 R 557723 CDS YP_002475586.1 219871211 7277087 complement(1017621..1018556) 1 NC_011852.1 ADP-heptose--LPS heptosyltransferase 1018556 7277087 HAPS_1019 Haemophilus parasuis SH0165 ADP-heptose--LPS heptosyltransferase YP_002475586.1 1017621 R 557723 CDS YP_002475587.1 219871212 7277088 complement(1018583..1019257) 1 NC_011852.1 COG:M;COG3306; lipooligosaccharide galactosyltransferase I 1019257 lbgA 7277088 lbgA Haemophilus parasuis SH0165 lipooligosaccharide galactosyltransferase I YP_002475587.1 1018583 R 557723 CDS YP_002475588.1 219871213 7277089 complement(1019260..1020405) 1 NC_011852.1 group 1 glycosyl transferase 1020405 7277089 HAPS_1021 Haemophilus parasuis SH0165 group 1 glycosyl transferase YP_002475588.1 1019260 R 557723 CDS YP_002475589.1 219871214 7277090 complement(1020395..1021567) 1 NC_011852.1 COG:M;COG0438; group 1 glycosyl transferase 1021567 7277090 HAPS_1022 Haemophilus parasuis SH0165 group 1 glycosyl transferase YP_002475589.1 1020395 R 557723 CDS YP_002475590.1 219871215 7277091 complement(1021571..1022362) 1 NC_011852.1 COG:M;COG3306; lipooligosaccharide biosynthesis protein lpsA 1022362 lpsA 7277091 lpsA Haemophilus parasuis SH0165 lipooligosaccharide biosynthesis protein lpsA YP_002475590.1 1021571 R 557723 CDS YP_002475591.1 219871216 7277092 complement(1022586..1022963) 1 NC_011852.1 hypothetical protein 1022963 7277092 HAPS_1024 Haemophilus parasuis SH0165 hypothetical protein YP_002475591.1 1022586 R 557723 CDS YP_002475592.1 219871217 7277093 complement(1022960..1023106) 1 NC_011852.1 hypothetical protein 1023106 7277093 HAPS_1025 Haemophilus parasuis SH0165 hypothetical protein YP_002475592.1 1022960 R 557723 CDS YP_002475593.1 219871218 7277094 complement(1023216..1023428) 1 NC_011852.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1023428 rpmE 7277094 rpmE Haemophilus parasuis SH0165 50S ribosomal protein L31 YP_002475593.1 1023216 R 557723 CDS YP_002475594.1 219871219 7277095 1023687..1024784 1 NC_011852.1 COG:L;COG5433; ISAma3, family ISAs1 1024784 7277095 HAPS_1027 Haemophilus parasuis SH0165 ISAma3, family ISAs1 YP_002475594.1 1023687 D 557723 CDS YP_002475595.1 219871220 7277096 1024982..1025887 1 NC_011852.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 1025887 genX 7277096 genX Haemophilus parasuis SH0165 lysyl-tRNA synthetase YP_002475595.1 1024982 D 557723 CDS YP_002475596.1 219871221 7277097 1025997..1026779 1 NC_011852.1 COG:L;COG0084; putative Mg-dependent DNAse 1026779 tatD 7277097 tatD Haemophilus parasuis SH0165 putative Mg-dependent DNAse YP_002475596.1 1025997 D 557723 CDS YP_002475597.1 219871222 7277098 1026919..1027344 1 NC_011852.1 hypothetical protein 1027344 7277098 HAPS_1030 Haemophilus parasuis SH0165 hypothetical protein YP_002475597.1 1026919 D 557723 CDS YP_002475598.1 219871223 7277099 1027450..1028178 1 NC_011852.1 COG:S;COG2908; UDP-2,3-diacylglucosamine hydrolase 1028178 lpxH 7277099 lpxH Haemophilus parasuis SH0165 UDP-2,3-diacylglucosamine hydrolase YP_002475598.1 1027450 D 557723 CDS YP_002475599.1 219871224 7277100 1028179..1028979 1 NC_011852.1 COG:M;COG0463; cell wall biosynthesis glycosyltransferase 1028979 vimF 7277100 vimF Haemophilus parasuis SH0165 cell wall biosynthesis glycosyltransferase YP_002475599.1 1028179 D 557723 CDS YP_002475600.1 219871225 7277101 complement(1028987..1030945) 1 NC_011852.1 COG:TK;COG0317; guanosine polyphosphate pyrophosphohydrolase/synthetase 1030945 spoT 7277101 spoT Haemophilus parasuis SH0165 guanosine polyphosphate pyrophosphohydrolase/synthetase YP_002475600.1 1028987 R 557723 CDS YP_002475601.1 219871226 7277102 1031134..1031247 1 NC_011852.1 hypothetical protein 1031247 7277102 HAPS_1034 Haemophilus parasuis SH0165 hypothetical protein YP_002475601.1 1031134 D 557723 CDS YP_002475602.1 219871227 7277103 complement(1031210..1031491) 1 NC_011852.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1031491 rpoZ 7277103 rpoZ Haemophilus parasuis SH0165 DNA-directed RNA polymerase subunit omega YP_002475602.1 1031210 R 557723 CDS YP_002475603.1 219871228 7277104 complement(1031853..1032803) 1 NC_011852.1 COG:G;COG0176; transaldolase B 1032803 talB 7277104 talB Haemophilus parasuis SH0165 transaldolase B YP_002475603.1 1031853 R 557723 CDS YP_002475604.1 219871229 7277105 complement(1032918..1034189) 1 NC_011852.1 COG:GEPR;COG0477; permease 1034189 ampG 7277105 ampG Haemophilus parasuis SH0165 permease YP_002475604.1 1032918 R 557723 CDS YP_002475605.1 219871230 7277106 complement(1034192..1035208) 1 NC_011852.1 COG:M;COG1087; UDP-glucose-4-epimerase 1035208 galE 7277106 galE Haemophilus parasuis SH0165 UDP-glucose-4-epimerase YP_002475605.1 1034192 R 557723 CDS YP_002475606.1 219871231 7277107 complement(1035273..1035935) 1 NC_011852.1 COG:J;COG1187; pseudouridylate synthase 1035935 rluB 7277107 rluB Haemophilus parasuis SH0165 pseudouridylate synthase YP_002475606.1 1035273 R 557723 CDS YP_002475607.1 219871232 7277108 1036098..1036427 1 NC_011852.1 COG:S;COG0718; hypothetical protein 1036427 7277108 HAPS_1040 Haemophilus parasuis SH0165 hypothetical protein YP_002475607.1 1036098 D 557723 CDS YP_002475608.1 219871233 7277109 1036494..1037099 1 NC_011852.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1037099 recR 7277109 recR Haemophilus parasuis SH0165 recombination protein RecR YP_002475608.1 1036494 D 557723 CDS YP_002475609.1 219871234 7277110 1037210..1038844 1 NC_011852.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1038844 pyrG 7277110 pyrG Haemophilus parasuis SH0165 CTP synthetase YP_002475609.1 1037210 D 557723 CDS YP_002475610.1 219871235 7277111 complement(1038956..1040188) 1 NC_011852.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1040188 serA 7277111 serA Haemophilus parasuis SH0165 D-3-phosphoglycerate dehydrogenase YP_002475610.1 1038956 R 557723 CDS YP_002475611.1 219871236 7277112 complement(1040251..1040910) 1 NC_011852.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1040910 rpiA 7277112 rpiA Haemophilus parasuis SH0165 ribose-5-phosphate isomerase A YP_002475611.1 1040251 R 557723 CDS YP_002475612.1 219871237 7277113 complement(1041009..1042343) 1 NC_011852.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1042343 glmM 7277113 glmM Haemophilus parasuis SH0165 phosphoglucosamine mutase YP_002475612.1 1041009 R 557723 CDS YP_002475613.1 219871238 7277114 complement(1042350..1043876) 1 NC_011852.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 1043876 ilvA 7277114 ilvA Haemophilus parasuis SH0165 threonine dehydratase YP_002475613.1 1042350 R 557723 CDS YP_002475614.1 219871239 7277115 complement(1043895..1044461) 1 NC_011852.1 COG:O;COG1047; FkbP-type peptidyl-prolyl cis-trans isomerase 1044461 slyD 7277115 slyD Haemophilus parasuis SH0165 FkbP-type peptidyl-prolyl cis-trans isomerase YP_002475614.1 1043895 R 557723 CDS YP_002475615.1 219871240 7277116 complement(1044579..1044719) 1 NC_011852.1 hypothetical protein 1044719 7277116 HAPS_1048 Haemophilus parasuis SH0165 hypothetical protein YP_002475615.1 1044579 R 557723 CDS YP_002475616.1 219871241 7277117 complement(1044728..1045432) 1 NC_011852.1 COG:S;COG3471; periplasmic/secreted protein 1045432 7277117 HAPS_1049 Haemophilus parasuis SH0165 periplasmic/secreted protein YP_002475616.1 1044728 R 557723 CDS YP_002475617.1 219871242 7277118 complement(1045484..1046221) 1 NC_011852.1 COG:S;COG1720; potassium-tellurite ethidium and proflavin transporter 1046221 7277118 HAPS_1050 Haemophilus parasuis SH0165 potassium-tellurite ethidium and proflavin transporter YP_002475617.1 1045484 R 557723 CDS YP_002475618.1 219871243 7277119 1046341..1047231 1 NC_011852.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1047231 menA 7277119 menA Haemophilus parasuis SH0165 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002475618.1 1046341 D 557723 CDS YP_002475619.1 219871244 7277120 complement(1047266..1047427) 1 NC_011852.1 COG:S;COG2835; hypothetical protein 1047427 7277120 HAPS_1052 Haemophilus parasuis SH0165 hypothetical protein YP_002475619.1 1047266 R 557723 CDS YP_002475620.1 219871245 7277121 complement(1047408..1048430) 1 NC_011852.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1048430 lpxK 7277121 lpxK Haemophilus parasuis SH0165 tetraacyldisaccharide 4'-kinase YP_002475620.1 1047408 R 557723 CDS YP_002475621.1 219871246 7277122 1049117..1049512 1 NC_011852.1 COG:P;COG3721; heme utilization protein HuvX 1049512 hugX 7277122 hugX Haemophilus parasuis SH0165 heme utilization protein HuvX YP_002475621.1 1049117 D 557723 CDS YP_002475622.1 219871247 7277124 1049526..1050065 1 NC_011852.1 COG:P;COG0748; heme utilization protein 1050065 hugZ 7277124 hugZ Haemophilus parasuis SH0165 heme utilization protein YP_002475622.1 1049526 D 557723 CDS YP_002475623.1 219871248 7277125 complement(1050129..1051637) 1 NC_011852.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1051637 glpK 7277125 glpK Haemophilus parasuis SH0165 glycerol kinase YP_002475623.1 1050129 R 557723 CDS YP_002475624.1 219871249 7277126 complement(1051711..1052424) 1 NC_011852.1 COG:G;COG0580; glycerol uptake facilitator protein 1052424 glpF 7277126 glpF Haemophilus parasuis SH0165 glycerol uptake facilitator protein YP_002475624.1 1051711 R 557723 CDS YP_002475625.1 219871250 7277127 complement(1052617..1053339) 1 NC_011852.1 COG:M;COG1922; putative UDP-N-acetyl-D-mannosaminuronic acid transferase 1053339 wecG 7277127 wecG Haemophilus parasuis SH0165 putative UDP-N-acetyl-D-mannosaminuronic acid transferase YP_002475625.1 1052617 R 557723 CDS YP_002475626.1 219871251 7277128 complement(1053332..1054591) 1 NC_011852.1 enterobacterial common antigen polymerase; putative common antigen polymerase 1054591 7277128 HAPS_1060 Haemophilus parasuis SH0165 putative common antigen polymerase YP_002475626.1 1053332 R 557723 CDS YP_002475627.1 219871252 7277129 complement(1054632..1055801) 1 NC_011852.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 1055801 wecF 7277129 wecF Haemophilus parasuis SH0165 4-alpha-L-fucosyltransferase YP_002475627.1 1054632 R 557723 CDS YP_002475628.1 219871253 7277130 1055944..1058328 1 NC_011852.1 COG:M;COG0744; penicillin-binding protein 1B (PBP1b) 1058328 pbpB 7277130 pbpB Haemophilus parasuis SH0165 penicillin-binding protein 1B (PBP1b) YP_002475628.1 1055944 D 557723 CDS YP_002475629.1 219871254 7277131 complement(1058407..1059090) 1 NC_011852.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 1059090 artM 7277131 artM Haemophilus parasuis SH0165 arginine transporter permease subunit ArtM YP_002475629.1 1058407 R 557723 CDS YP_002475630.1 219871255 7277132 complement(1059090..1059719) 1 NC_011852.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 1059719 artQ 7277132 artQ Haemophilus parasuis SH0165 arginine transporter permease subunit ArtQ YP_002475630.1 1059090 R 557723 CDS YP_002475631.1 219871256 7277133 complement(1059767..1060492) 1 NC_011852.1 COG:ET;COG0834; amino acid ABC transporter/signal transduction systems, periplasmic component 1060492 artI 7277133 artI Haemophilus parasuis SH0165 amino acid ABC transporter/signal transduction systems, periplasmic component YP_002475631.1 1059767 R 557723 CDS YP_002475632.1 219871257 7277134 complement(1060524..1061258) 1 NC_011852.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 1061258 artP 7277134 artP Haemophilus parasuis SH0165 arginine transporter ATP-binding subunit YP_002475632.1 1060524 R 557723 CDS YP_002475633.1 219871258 7277135 1061432..1063615 1 NC_011852.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 1063615 uvrD 7277135 uvrD Haemophilus parasuis SH0165 DNA-dependent helicase II YP_002475633.1 1061432 D 557723 CDS YP_002475634.1 219871259 7277136 complement(1063662..1064111) 1 NC_011852.1 COG:J;COG0359; 50S ribosomal protein L9 1064111 rplI 7277136 rplI Haemophilus parasuis SH0165 50S ribosomal protein L9 YP_002475634.1 1063662 R 557723 CDS YP_002475635.1 219871260 7277137 complement(1064130..1064357) 1 NC_011852.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1064357 rpsR 7277137 rpsR Haemophilus parasuis SH0165 30S ribosomal protein S18 YP_002475635.1 1064130 R 557723 CDS YP_002475636.1 219871261 7277138 complement(1064369..1064695) 1 NC_011852.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 1064695 priB 7277138 priB Haemophilus parasuis SH0165 primosomal replication protein N YP_002475636.1 1064369 R 557723 CDS YP_002475637.1 219871262 7277139 complement(1064682..1065062) 1 NC_011852.1 COG:J;COG0360; 30S ribosomal protein S6 1065062 rpsF 7277139 rpsF Haemophilus parasuis SH0165 30S ribosomal protein S6 YP_002475637.1 1064682 R 557723 CDS YP_002475638.1 219871263 7277140 1065460..1066779 1 NC_011852.1 COG:GEPR;COG0477; metabolite transport protein 1066779 7277140 HAPS_1072 Haemophilus parasuis SH0165 metabolite transport protein YP_002475638.1 1065460 D 557723 CDS YP_002475639.1 219871264 7277141 complement(1066804..1067586) 1 NC_011852.1 putative choline kinase involved in LPS biosynthesis 1067586 licA 7277141 licA Haemophilus parasuis SH0165 putative choline kinase involved in LPS biosynthesis YP_002475639.1 1066804 R 557723 CDS YP_002475640.1 219871265 7277142 complement(1067586..1067954) 1 NC_011852.1 COG:R;COG5633; lipoprotein 1067954 7277142 HAPS_1074 Haemophilus parasuis SH0165 lipoprotein YP_002475640.1 1067586 R 557723 CDS YP_002475641.1 219871266 7277143 complement(1067956..1068315) 1 NC_011852.1 COG:FGR;COG0537; HIT-like protein/diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 1068315 7277143 HAPS_1075 Haemophilus parasuis SH0165 HIT-like protein/diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases YP_002475641.1 1067956 R 557723 CDS YP_002475642.1 219871267 7277144 1068342..1068467 1 NC_011852.1 hypothetical protein 1068467 7277144 HAPS_1076 Haemophilus parasuis SH0165 hypothetical protein YP_002475642.1 1068342 D 557723 CDS YP_002475643.1 219871268 7277145 1068726..1069823 1 NC_011852.1 COG:L;COG5433; ISAma3, family ISAs1 1069823 7277145 HAPS_1077 Haemophilus parasuis SH0165 ISAma3, family ISAs1 YP_002475643.1 1068726 D 557723 CDS YP_002475644.1 219871269 7277146 complement(1070513..1071097) 1 NC_011852.1 may be involved in the utilization of double-stranded DNA as a carbon source; cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 1071097 orfG 7277146 orfG Haemophilus parasuis SH0165 putative DNA uptake protein YP_002475644.1 1070513 R 557723 CDS YP_002475645.1 219871270 7277147 1071492..1072838 1 NC_011852.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 1072838 nqrA 7277147 nqrA Haemophilus parasuis SH0165 Na(+)-translocating NADH-quinone reductase subunit A YP_002475645.1 1071492 D 557723 CDS YP_002475646.1 219871271 7277148 1072843..1074081 1 NC_011852.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 1074081 nqrB 7277148 nqrB Haemophilus parasuis SH0165 Na(+)-translocating NADH-quinone reductase subunit B YP_002475646.1 1072843 D 557723 CDS YP_002475647.1 219871272 7277149 1074074..1074850 1 NC_011852.1 COG:C;COG2869; Na(+)-translocating NADH-quinone reductase subunit C 1074850 nqrC 7277149 nqrC Haemophilus parasuis SH0165 Na(+)-translocating NADH-quinone reductase subunit C YP_002475647.1 1074074 D 557723 CDS YP_002475648.1 219871273 7277150 1074850..1075473 1 NC_011852.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 1075473 nqrD 7277150 nqrD Haemophilus parasuis SH0165 Na(+)-translocating NADH-quinone reductase subunit D YP_002475648.1 1074850 D 557723 CDS YP_002475649.1 219871274 7277151 1075475..1076071 1 NC_011852.1 COG:C;COG2209; Na(+)-translocating NADH-quinone reductase subunit E 1076071 nqrE 7277151 nqrE Haemophilus parasuis SH0165 Na(+)-translocating NADH-quinone reductase subunit E YP_002475649.1 1075475 D 557723 CDS YP_002475650.1 219871275 7277152 1076084..1077316 1 NC_011852.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 1077316 nqrF 7277152 nqrF Haemophilus parasuis SH0165 Na(+)-translocating NADH-quinone reductase subunit F YP_002475650.1 1076084 D 557723 CDS YP_002475651.1 219871276 7277153 1077397..1077825 1 NC_011852.1 nucleotidyltransferase, inorganic polyphosphate/ATP-NAD kinase 1077825 7277153 HAPS_1085 Haemophilus parasuis SH0165 nucleotidyltransferase, inorganic polyphosphate/ATP-NAD kinase YP_002475651.1 1077397 D 557723 CDS YP_002475652.1 219871277 7277154 1077822..1078121 1 NC_011852.1 COG:R;COG1708; DNA polymerase subunit beta 1078121 dnaN 7277154 dnaN Haemophilus parasuis SH0165 DNA polymerase subunit beta YP_002475652.1 1077822 D 557723 CDS YP_002475653.1 219871278 7277155 complement(1078118..1079695) 1 NC_011852.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1079695 thiP 7277155 thiP Haemophilus parasuis SH0165 thiamine transporter membrane protein YP_002475653.1 1078118 R 557723 CDS YP_002475654.1 219871279 7277156 1080020..1081459 1 NC_011852.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 1081459 nrfA 7277156 nrfA Haemophilus parasuis SH0165 cytochrome c552 YP_002475654.1 1080020 D 557723 CDS YP_002475655.1 219871280 7277157 1081480..1082103 1 NC_011852.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 1082103 nrfB 7277157 nrfB Haemophilus parasuis SH0165 cytochrome c nitrite reductase pentaheme subunit YP_002475655.1 1081480 D 557723 CDS YP_002475656.1 219871281 7277076 1082100..1082777 1 NC_011852.1 COG:C;COG0437; nitrate reductase 1082777 nrfC 7277076 nrfC Haemophilus parasuis SH0165 nitrate reductase YP_002475656.1 1082100 D 557723 CDS YP_002475657.1 219871282 7278815 1082777..1083730 1 NC_011852.1 COG:P;COG3301; nitrate reductase, transmembrane protein 1083730 nrfD 7278815 nrfD Haemophilus parasuis SH0165 nitrate reductase, transmembrane protein YP_002475657.1 1082777 D 557723 CDS YP_002475658.1 219871283 7278816 1083840..1084628 1 NC_011852.1 COG:M;COG3774; glycosyltransferase 1084628 7278816 HAPS_1092 Haemophilus parasuis SH0165 glycosyltransferase YP_002475658.1 1083840 D 557723 CDS YP_002475659.1 219871284 7278818 1085685..1086350 1 NC_011852.1 COG:R;COG3726; AphA-like protein/membrane protein affecting hemolysin expression 1086350 aphA 7278818 aphA Haemophilus parasuis SH0165 AphA-like protein/membrane protein affecting hemolysin expression YP_002475659.1 1085685 D 557723 CDS YP_002475660.1 219871285 7278819 1086446..1086664 1 NC_011852.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1086664 infA 7278819 infA Haemophilus parasuis SH0165 translation initiation factor IF-1 YP_002475660.1 1086446 D 557723 CDS YP_002475661.1 219871286 7278820 1086850..1087782 1 NC_011852.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1087782 engC 7278820 engC Haemophilus parasuis SH0165 ribosome-associated GTPase YP_002475661.1 1086850 D 557723 CDS YP_002475662.1 219871287 7278821 1087974..1088852 1 NC_011852.1 COG:P;COG0803; chelated iron ABC transporter periplasmic-binding protein 1088852 yfeA 7278821 yfeA Haemophilus parasuis SH0165 chelated iron ABC transporter periplasmic-binding protein YP_002475662.1 1087974 D 557723 CDS YP_002475663.1 219871288 7278822 1088915..1089676 1 NC_011852.1 COG:P;COG1121; chelated iron ABC transporter ATP-binding protein 1089676 yfeB 7278822 yfeB Haemophilus parasuis SH0165 chelated iron ABC transporter ATP-binding protein YP_002475663.1 1088915 D 557723 CDS YP_002475664.1 219871289 7278823 1089680..1090552 1 NC_011852.1 COG:P;COG1108; chelated iron ABC transporter permease 1090552 yfeC 7278823 yfeC Haemophilus parasuis SH0165 chelated iron ABC transporter permease YP_002475664.1 1089680 D 557723 CDS YP_002475665.1 219871290 7278824 1090552..1091391 1 NC_011852.1 COG:P;COG1108; chelated iron ABC transporter permease 1091391 yfeD 7278824 yfeD Haemophilus parasuis SH0165 chelated iron ABC transporter permease YP_002475665.1 1090552 D 557723 CDS YP_002475666.1 219871291 7278825 complement(1091462..1091875) 1 NC_011852.1 COG:S;COG4316; hypothetical protein 1091875 7278825 HAPS_1101 Haemophilus parasuis SH0165 hypothetical protein YP_002475666.1 1091462 R 557723 CDS YP_002475667.1 219871292 7278828 1093171..1093512 1 NC_011852.1 COG:K;COG1396; XRE family transcriptional regulator 1093512 7278828 HAPS_1104 Haemophilus parasuis SH0165 XRE family transcriptional regulator YP_002475667.1 1093171 D 557723 CDS YP_002475668.1 219871293 7278829 complement(1093682..1095118) 1 NC_011852.1 COG:G;COG1621; sucrose-6-phosphate hydrolase 1095118 scrB 7278829 scrB Haemophilus parasuis SH0165 sucrose-6-phosphate hydrolase YP_002475668.1 1093682 R 557723 CDS YP_002475669.1 219871294 7278831 1096546..1096866 1 NC_011852.1 COG:P;COG2824; alkylphosphonate uptake protein 1096866 phnA 7278831 phnA Haemophilus parasuis SH0165 alkylphosphonate uptake protein YP_002475669.1 1096546 D 557723 CDS YP_002475670.1 219871295 7278832 1096942..1097562 1 NC_011852.1 COG:F;COG0299; phosphoribosylglycinamide formyltransferase 1097562 purN 7278832 purN Haemophilus parasuis SH0165 phosphoribosylglycinamide formyltransferase YP_002475670.1 1096942 D 557723 CDS YP_002475671.1 219871296 7278833 1097770..1099197 1 NC_011852.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1099197 aspA 7278833 aspA Haemophilus parasuis SH0165 aspartate ammonia-lyase YP_002475671.1 1097770 D 557723 CDS YP_002475672.1 219871297 7278834 complement(1099204..1099407) 1 NC_011852.1 hypothetical protein 1099407 7278834 HAPS_1110 Haemophilus parasuis SH0165 hypothetical protein YP_002475672.1 1099204 R 557723 CDS YP_002475673.1 219871298 7278835 1099432..1101318 1 NC_011852.1 molecular chaperone; heat shock protein 90 1101318 htpG 7278835 htpG Haemophilus parasuis SH0165 heat shock protein 90 YP_002475673.1 1099432 D 557723 CDS YP_002475674.1 219871299 7278836 complement(1101543..1102391) 1 NC_011852.1 COG:M;COG2027; D-alanyl-D-alanine carboxypeptidase 1102391 dacB 7278836 dacB Haemophilus parasuis SH0165 D-alanyl-D-alanine carboxypeptidase YP_002475674.1 1101543 R 557723 CDS YP_002475675.1 219871300 7278837 1102511..1102987 1 NC_011852.1 COG:K;COG0782; transcription elongation factor GreA 1102987 greA 7278837 greA Haemophilus parasuis SH0165 transcription elongation factor GreA YP_002475675.1 1102511 D 557723 CDS YP_002475676.1 219871301 7278839 complement(1104258..1105064) 1 NC_011852.1 COG:E;COG4608; oligopeptide ABC transporter ATP-binding subunit 1105064 oppF 7278839 oppF Haemophilus parasuis SH0165 oligopeptide ABC transporter ATP-binding subunit YP_002475676.1 1104258 R 557723 CDS YP_002475677.1 219871302 7278840 complement(1105068..1107023) 1 NC_011852.1 oligopeptide ABC transporter ATP-binding/permease 1107023 oppCD 7278840 oppCD Haemophilus parasuis SH0165 oligopeptide ABC transporter ATP-binding/permease YP_002475677.1 1105068 R 557723 CDS YP_002475678.1 219871303 7278841 complement(1107023..1107940) 1 NC_011852.1 COG:EP;COG0601; oligopeptide ABC transporter permease 1107940 oppB 7278841 oppB Haemophilus parasuis SH0165 oligopeptide ABC transporter permease YP_002475678.1 1107023 R 557723 CDS YP_002475679.1 219871304 7278842 complement(1108151..1109734) 1 NC_011852.1 COG:E;COG0747; oligopeptide ABC transporter periplasmic binding protein 1109734 oppA 7278842 oppA Haemophilus parasuis SH0165 oligopeptide ABC transporter periplasmic binding protein YP_002475679.1 1108151 R 557723 CDS YP_002475680.1 219871305 7278843 complement(1109966..1110427) 1 NC_011852.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1110427 rnhA 7278843 rnhA Haemophilus parasuis SH0165 ribonuclease H YP_002475680.1 1109966 R 557723 CDS YP_002475681.1 219871306 7278844 complement(1110433..1111269) 1 NC_011852.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1111269 purU 7278844 purU Haemophilus parasuis SH0165 formyltetrahydrofolate deformylase YP_002475681.1 1110433 R 557723 CDS YP_002475682.1 219871307 7278845 complement(1111365..1111769) 1 NC_011852.1 COG:R;COG2916; DNA-binding protein H-NS 1111769 hns 7278845 hns Haemophilus parasuis SH0165 DNA-binding protein H-NS YP_002475682.1 1111365 R 557723 CDS YP_002475683.1 219871308 7278846 1112281..1113807 1 NC_011852.1 COG:C;COG1757; Na(+)/H(+) antiporter 1113807 7278846 HAPS_1122 Haemophilus parasuis SH0165 Na(+)/H(+) antiporter YP_002475683.1 1112281 D 557723 CDS YP_002475684.1 219871309 7278847 1113925..1115826 1 NC_011852.1 COG:O;COG1138; cytochrome c-type biogenesis protein 1115826 nfrE 7278847 nfrE Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein YP_002475684.1 1113925 D 557723 CDS YP_002475685.1 219871310 7278848 1115823..1116359 1 NC_011852.1 COG:OC;COG0526; thiol:disulfide interchange protein DsbE 1116359 dsbE 7278848 dsbE Haemophilus parasuis SH0165 thiol:disulfide interchange protein DsbE YP_002475685.1 1115823 D 557723 CDS YP_002475686.1 219871311 7278849 1116356..1116748 1 NC_011852.1 COG:O;COG3088; cytochrome c-type biogenesis protein ccmH 1116748 ccmH 7278849 ccmH Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein ccmH YP_002475686.1 1116356 D 557723 CDS YP_002475687.1 219871312 7278850 1116741..1117487 1 NC_011852.1 COG:O;COG4235; formate-dependent nitrite reductase complex NrfG subunit, cytochrome c biogenesis factor 1117487 nrfG 7278850 nrfG Haemophilus parasuis SH0165 formate-dependent nitrite reductase complex NrfG subunit, cytochrome c biogenesis factor YP_002475687.1 1116741 D 557723 CDS YP_002475688.1 219871313 7278851 complement(1117554..1118576) 1 NC_011852.1 COG:E;COG3842; iron(III) ABC transporter ATP-binding protein 1118576 fbpC 7278851 fbpC Haemophilus parasuis SH0165 iron(III) ABC transporter ATP-binding protein YP_002475688.1 1117554 R 557723 CDS YP_002475689.1 219871314 7278852 complement(1118578..1120230) 1 NC_011852.1 COG:P;COG1178; iron-uptake permease inner membrane protein 1120230 fbpB 7278852 fbpB Haemophilus parasuis SH0165 iron-uptake permease inner membrane protein YP_002475689.1 1118578 R 557723 CDS YP_002475690.1 219871315 7278853 complement(1120408..1121433) 1 NC_011852.1 COG:P;COG1840; periplasmic iron-binding protein 1121433 fbpA 7278853 fbpA Haemophilus parasuis SH0165 periplasmic iron-binding protein YP_002475690.1 1120408 R 557723 CDS YP_002475691.1 219871316 7278854 1122061..1123458 1 NC_011852.1 COG:P;COG1858; cytochrome c peroxidase 1123458 ccp 7278854 ccp Haemophilus parasuis SH0165 cytochrome c peroxidase YP_002475691.1 1122061 D 557723 CDS YP_002475692.1 219871317 7278855 complement(1123639..1123908) 1 NC_011852.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1123908 rpsO 7278855 rpsO Haemophilus parasuis SH0165 30S ribosomal protein S15 YP_002475692.1 1123639 R 557723 CDS YP_002475693.1 219871318 7278856 complement(1124040..1125359) 1 NC_011852.1 COG:P;COG0025; NhaP-type Na+/H+ and K+/H+ antiporter 1125359 nhaP 7278856 nhaP Haemophilus parasuis SH0165 NhaP-type Na+/H+ and K+/H+ antiporter YP_002475693.1 1124040 R 557723 CDS YP_002475694.1 219871319 7278857 1125551..1127425 1 NC_011852.1 COG:O;COG0760; peptidyl-prolyl cis-trans isomerase D 1127425 ppiD 7278857 ppiD Haemophilus parasuis SH0165 peptidyl-prolyl cis-trans isomerase D YP_002475694.1 1125551 D 557723 CDS YP_002475695.1 219871320 7278858 1127876..1128967 1 NC_011852.1 COG:H;COG1985; riboflavin biosynthesis protein RibD 1128967 ribD 7278858 ribD Haemophilus parasuis SH0165 riboflavin biosynthesis protein RibD YP_002475695.1 1127876 D 557723 CDS YP_002475696.1 219871321 7278859 1128969..1129613 1 NC_011852.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1129613 ribE 7278859 ribE Haemophilus parasuis SH0165 riboflavin synthase subunit alpha YP_002475696.1 1128969 D 557723 CDS YP_002475697.1 219871322 7278860 1129745..1130944 1 NC_011852.1 COG:H;COG0108; riboflavin biosynthesis protein ribA 1130944 ribA 7278860 ribA Haemophilus parasuis SH0165 riboflavin biosynthesis protein ribA YP_002475697.1 1129745 D 557723 CDS YP_002475698.1 219871323 7278861 1131140..1131601 1 NC_011852.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1131601 ribH 7278861 ribH Haemophilus parasuis SH0165 6,7-dimethyl-8-ribityllumazine synthase YP_002475698.1 1131140 D 557723 CDS YP_002475699.1 219871324 7278862 complement(1131713..1132504) 1 NC_011852.1 COG:R;COG1101; ABC transporter ATP-binding protein 1132504 7278862 HAPS_1138 Haemophilus parasuis SH0165 ABC transporter ATP-binding protein YP_002475699.1 1131713 R 557723 CDS YP_002475700.1 219871325 7278863 complement(1132504..1133439) 1 NC_011852.1 COG:R;COG4120; ABC transporter inner membrane subunit 1133439 7278863 HAPS_1139 Haemophilus parasuis SH0165 ABC transporter inner membrane subunit YP_002475700.1 1132504 R 557723 CDS YP_002475701.1 219871326 7278864 complement(1133491..1133610) 1 NC_011852.1 hypothetical protein 1133610 7278864 HAPS_1140 Haemophilus parasuis SH0165 hypothetical protein YP_002475701.1 1133491 R 557723 CDS YP_002475702.1 219871327 7278865 1133632..1133850 1 NC_011852.1 L-lactate dehydrogenase 1133850 ldhL 7278865 ldhL Haemophilus parasuis SH0165 L-lactate dehydrogenase YP_002475702.1 1133632 D 557723 CDS YP_002475703.1 219871328 7278866 complement(1133964..1134104) 1 NC_011852.1 hypothetical protein 1134104 7278866 HAPS_1142 Haemophilus parasuis SH0165 hypothetical protein YP_002475703.1 1133964 R 557723 CDS YP_002475704.1 219871329 7278867 complement(1134129..1135571) 1 NC_011852.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 1135571 7278867 HAPS_1143 Haemophilus parasuis SH0165 putative transglycosylase YP_002475704.1 1134129 R 557723 CDS YP_002475705.1 219871330 7278868 complement(1135678..1136532) 1 NC_011852.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1136532 folD 7278868 folD Haemophilus parasuis SH0165 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002475705.1 1135678 R 557723 CDS YP_002475706.1 219871331 7278871 complement(1136938..1137993) 1 NC_011852.1 COG:L;COG0582; phage integrase 1137993 int 7278871 int Haemophilus parasuis SH0165 phage integrase YP_002475706.1 1136938 R 557723 CDS YP_002475707.1 219871332 7278872 complement(1138292..1139095) 1 NC_011852.1 putative prophage antirepressor 1139095 7278872 HAPS_1148 Haemophilus parasuis SH0165 putative prophage antirepressor YP_002475707.1 1138292 R 557723 CDS YP_002475708.1 219871333 7278873 complement(1139481..1140578) 1 NC_011852.1 COG:L;COG5433; ISAma3, family ISAs1 1140578 7278873 HAPS_1149 Haemophilus parasuis SH0165 ISAma3, family ISAs1 YP_002475708.1 1139481 R 557723 CDS YP_002475709.1 219871334 7278874 complement(1140667..1141122) 1 NC_011852.1 COG:S;COG5346; putative inner membrane protein 1141122 7278874 HAPS_1150 Haemophilus parasuis SH0165 putative inner membrane protein YP_002475709.1 1140667 R 557723 CDS YP_002475710.1 219871335 7278875 complement(1141106..1141303) 1 NC_011852.1 hypothetical protein 1141303 7278875 HAPS_1151 Haemophilus parasuis SH0165 hypothetical protein YP_002475710.1 1141106 R 557723 CDS YP_002475711.1 219871336 7278876 complement(1141572..1141952) 1 NC_011852.1 COG:S;COG3692; putative phage associated protein 1141952 7278876 HAPS_1152 Haemophilus parasuis SH0165 putative phage associated protein YP_002475711.1 1141572 R 557723 CDS YP_002475712.1 219871337 7278877 1142318..1142530 1 NC_011852.1 hypothetical protein 1142530 7278877 HAPS_1153 Haemophilus parasuis SH0165 hypothetical protein YP_002475712.1 1142318 D 557723 CDS YP_002475713.1 219871338 7278878 complement(1142549..1142812) 1 NC_011852.1 hypothetical protein 1142812 7278878 HAPS_1154 Haemophilus parasuis SH0165 hypothetical protein YP_002475713.1 1142549 R 557723 CDS YP_002475714.1 219871339 7278879 complement(1142836..1143375) 1 NC_011852.1 phage-like protein 1143375 7278879 HAPS_1155 Haemophilus parasuis SH0165 phage-like protein YP_002475714.1 1142836 R 557723 CDS YP_002475715.1 219871340 7278880 1143719..1143907 1 NC_011852.1 hypothetical protein 1143907 7278880 HAPS_1156 Haemophilus parasuis SH0165 hypothetical protein YP_002475715.1 1143719 D 557723 CDS YP_002475716.1 219871341 7278881 complement(1143949..1144563) 1 NC_011852.1 putative bacteriophage exonuclease 1144563 exo 7278881 exo Haemophilus parasuis SH0165 putative bacteriophage exonuclease YP_002475716.1 1143949 R 557723 CDS YP_002475717.1 219871342 7278882 complement(1144560..1145426) 1 NC_011852.1 phage recombination protein Bet 1145426 bet 7278882 bet Haemophilus parasuis SH0165 phage recombination protein Bet YP_002475717.1 1144560 R 557723 CDS YP_002475718.1 219871343 7278883 complement(1145436..1145894) 1 NC_011852.1 phage-like endonuclease protein 1145894 7278883 HAPS_1159 Haemophilus parasuis SH0165 phage-like endonuclease protein YP_002475718.1 1145436 R 557723 CDS YP_002475719.1 219871344 7278884 complement(1145903..1146061) 1 NC_011852.1 hypothetical protein 1146061 7278884 HAPS_1160 Haemophilus parasuis SH0165 hypothetical protein YP_002475719.1 1145903 R 557723 CDS YP_002475720.1 219871345 7278887 1146784..1148214 1 NC_011852.1 putative outer membrane protein 1148214 7278887 HAPS_1163 Haemophilus parasuis SH0165 putative outer membrane protein YP_002475720.1 1146784 D 557723 CDS YP_002475721.1 219871346 7278888 complement(1148211..1148822) 1 NC_011852.1 COG:H;COG0212; 5-formyltetrahydrofolate cyclo-ligase 1148822 7278888 HAPS_1164 Haemophilus parasuis SH0165 5-formyltetrahydrofolate cyclo-ligase YP_002475721.1 1148211 R 557723 CDS YP_002475722.1 219871347 7278889 complement(1149047..1149376) 1 NC_011852.1 COG:S;COG3027; cell division protein ZapA 1149376 zapA 7278889 zapA Haemophilus parasuis SH0165 cell division protein ZapA YP_002475722.1 1149047 R 557723 CDS YP_002475723.1 219871348 7278890 1149451..1149996 1 NC_011852.1 COG:S;COG3079; yecA family protein 1149996 7278890 HAPS_1166 Haemophilus parasuis SH0165 yecA family protein YP_002475723.1 1149451 D 557723 CDS YP_002475724.1 219871349 7278891 complement(1150021..1151802) 1 NC_011852.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 1151802 nrdD 7278891 nrdD Haemophilus parasuis SH0165 anaerobic ribonucleoside triphosphate reductase YP_002475724.1 1150021 R 557723 CDS YP_002475725.1 219871350 7278892 complement(1151799..1152269) 1 NC_011852.1 anaerobic ribonucleoside-triphosphate reductase activating protein 1152269 nrdG 7278892 nrdG Haemophilus parasuis SH0165 anaerobic ribonucleoside-triphosphate reductase activating protein YP_002475725.1 1151799 R 557723 CDS YP_002475726.1 219871351 7278893 complement(1152444..1153007) 1 NC_011852.1 catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; putative anthranilate synthase component II 1153007 trpG 7278893 trpG Haemophilus parasuis SH0165 putative anthranilate synthase component II YP_002475726.1 1152444 R 557723 CDS YP_002475727.1 219871352 7278894 complement(1153007..1154623) 1 NC_011852.1 COG:S;COG1322; DNA recombination protein RmuC-like protein 1154623 rmuC 7278894 rmuC Haemophilus parasuis SH0165 DNA recombination protein RmuC-like protein YP_002475727.1 1153007 R 557723 CDS YP_002475728.1 219871353 7278895 1154803..1155825 1 NC_011852.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1155825 hemB 7278895 hemB Haemophilus parasuis SH0165 delta-aminolevulinic acid dehydratase YP_002475728.1 1154803 D 557723 CDS YP_002475729.1 219871354 7278897 1156034..1156615 1 NC_011852.1 COG:T;COG0664; cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase 1156615 7278897 HAPS_1172 Haemophilus parasuis SH0165 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase YP_002475729.1 1156034 D 557723 CDS YP_002475730.1 219871355 7278898 1156622..1157833 1 NC_011852.1 COG:R;COG0641; arylsulfatase regulator 1157833 aslB 7278898 aslB Haemophilus parasuis SH0165 arylsulfatase regulator YP_002475730.1 1156622 D 557723 CDS YP_002475731.1 219871356 7278899 complement(1158100..1160919) 1 NC_011852.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 1160919 hepA 7278899 hepA Haemophilus parasuis SH0165 ATP-dependent helicase HepA YP_002475731.1 1158100 R 557723 CDS YP_002475732.1 219871357 7278900 complement(1161083..1162726) 1 NC_011852.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1162726 pgi 7278900 pgi Haemophilus parasuis SH0165 glucose-6-phosphate isomerase YP_002475732.1 1161083 R 557723 CDS YP_002475733.1 219871358 7278901 complement(1162745..1163005) 1 NC_011852.1 COG:S;COG2960; hypothetical protein 1163005 7278901 HAPS_1176 Haemophilus parasuis SH0165 hypothetical protein YP_002475733.1 1162745 R 557723 CDS YP_002475734.1 219871359 7278906 complement(1163690..1164508) 1 NC_011852.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1164508 aroE 7278906 aroE Haemophilus parasuis SH0165 shikimate 5-dehydrogenase YP_002475734.1 1163690 R 557723 CDS YP_002475735.1 219871360 7278907 complement(1164512..1165066) 1 NC_011852.1 COG:J;COG0009; SUA5 protein translation factor 1165066 sua5 7278907 sua5 Haemophilus parasuis SH0165 SUA5 protein translation factor YP_002475735.1 1164512 R 557723 CDS YP_002475736.1 219871361 7278908 complement(1165066..1165596) 1 NC_011852.1 COG:L;COG0551; DNA topoisomerase I-like protein 1165596 7278908 HAPS_1183 Haemophilus parasuis SH0165 DNA topoisomerase I-like protein YP_002475736.1 1165066 R 557723 CDS YP_002475737.1 219871362 7278909 complement(1165604..1165909) 1 NC_011852.1 COG:S;COG3097; hypothetical protein 1165909 7278909 HAPS_1184 Haemophilus parasuis SH0165 hypothetical protein YP_002475737.1 1165604 R 557723 CDS YP_002475738.1 219871363 7278910 complement(1165902..1166357) 1 NC_011852.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1166357 recX 7278910 recX Haemophilus parasuis SH0165 recombination regulator RecX YP_002475738.1 1165902 R 557723 CDS YP_002475739.1 219871364 7278911 complement(1166410..1167528) 1 NC_011852.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1167528 recA 7278911 recA Haemophilus parasuis SH0165 recombinase A YP_002475739.1 1166410 R 557723 CDS YP_002475740.1 219871365 7278912 complement(1167661..1168266) 1 NC_011852.1 COG:EH;COG0115; hypothetical protein 1168266 7278912 HAPS_1187 Haemophilus parasuis SH0165 hypothetical protein YP_002475740.1 1167661 R 557723 CDS YP_002475741.1 219871366 7278913 complement(1168244..1169215) 1 NC_011852.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I 1169215 pabB 7278913 pabB Haemophilus parasuis SH0165 para-aminobenzoate synthase component I YP_002475741.1 1168244 R 557723 CDS YP_002475742.1 219871367 7278915 1169438..1169551 1 NC_011852.1 hypothetical protein 1169551 7278915 HAPS_1190 Haemophilus parasuis SH0165 hypothetical protein YP_002475742.1 1169438 D 557723 CDS YP_002475743.1 219871368 7278916 1169666..1170529 1 NC_011852.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1170529 tehB 7278916 tehB Haemophilus parasuis SH0165 tellurite resistance protein TehB YP_002475743.1 1169666 D 557723 CDS YP_002475744.1 219871369 7278917 1170805..1171776 1 NC_011852.1 COG:J;COG0042; tRNA-dihydrouridine synthase A 1171776 dusA 7278917 dusA Haemophilus parasuis SH0165 tRNA-dihydrouridine synthase A YP_002475744.1 1170805 D 557723 CDS YP_002475745.1 219871370 7278919 complement(1172905..1174770) 1 NC_011852.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1174770 rpoD 7278919 rpoD Haemophilus parasuis SH0165 RNA polymerase sigma factor RpoD YP_002475745.1 1172905 R 557723 CDS YP_002475746.1 219871371 7278920 complement(1174869..1176617) 1 NC_011852.1 synthesizes RNA primers at the replication forks; DNA primase 1176617 dnaG 7278920 dnaG Haemophilus parasuis SH0165 DNA primase YP_002475746.1 1174869 R 557723 CDS YP_002475747.1 219871372 7278921 complement(1176761..1176976) 1 NC_011852.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1176976 rpsU 7278921 rpsU Haemophilus parasuis SH0165 30S ribosomal protein S21 YP_002475747.1 1176761 R 557723 CDS YP_002475748.1 219871373 7278922 complement(1177535..1177750) 1 NC_011852.1 hypothetical protein 1177750 7278922 HAPS_1197 Haemophilus parasuis SH0165 hypothetical protein YP_002475748.1 1177535 R 557723 CDS YP_002475749.1 219871374 7278923 complement(1177843..1180752) 1 NC_011852.1 COG:J;COG1530; ribonuclease E 1180752 rne 7278923 rne Haemophilus parasuis SH0165 ribonuclease E YP_002475749.1 1177843 R 557723 CDS YP_002475750.1 219871375 7278924 complement(1181084..1182472) 1 NC_011852.1 COG:M;COG0773; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 1182472 mpl 7278924 mpl Haemophilus parasuis SH0165 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_002475750.1 1181084 R 557723 CDS YP_002475751.1 219871376 7278925 1182594..1183595 1 NC_011852.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1183595 fbp 7278925 fbp Haemophilus parasuis SH0165 fructose-1,6-bisphosphatase YP_002475751.1 1182594 D 557723 CDS YP_002475752.1 219871377 7278926 1183621..1183746 1 NC_011852.1 hypothetical protein 1183746 7278926 HAPS_1201 Haemophilus parasuis SH0165 hypothetical protein YP_002475752.1 1183621 D 557723 CDS YP_002475753.1 219871378 7278927 1183743..1185338 1 NC_011852.1 COG:E;COG0747; heme-binding protein A 1185338 hbpA 7278927 hbpA Haemophilus parasuis SH0165 heme-binding protein A YP_002475753.1 1183743 D 557723 CDS YP_002475754.1 219871379 7278928 1185469..1186491 1 NC_011852.1 COG:K;COG1609; sucrose operon repressor 1186491 scrR 7278928 scrR Haemophilus parasuis SH0165 sucrose operon repressor YP_002475754.1 1185469 D 557723 CDS YP_002475755.1 219871380 7278929 1186644..1188242 1 NC_011852.1 COG:KE;COG3283; transcriptional regulatory protein TyrR 1188242 tyrR 7278929 tyrR Haemophilus parasuis SH0165 transcriptional regulatory protein TyrR YP_002475755.1 1186644 D 557723 CDS YP_002475756.1 219871381 7278930 1188239..1189879 1 NC_011852.1 COG:E;COG4166; peptide transport periplasmic protein SapA 1189879 sapA 7278930 sapA Haemophilus parasuis SH0165 peptide transport periplasmic protein SapA YP_002475756.1 1188239 D 557723 CDS YP_002475757.1 219871382 7278931 1189881..1190843 1 NC_011852.1 COG:V;COG4168; peptide transport system permease SapB 1190843 sapB 7278931 sapB Haemophilus parasuis SH0165 peptide transport system permease SapB YP_002475757.1 1189881 D 557723 CDS YP_002475758.1 219871383 7278932 1191031..1191924 1 NC_011852.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 1191924 psd 7278932 psd Haemophilus parasuis SH0165 phosphatidylserine decarboxylase YP_002475758.1 1191031 D 557723 CDS YP_002475759.1 219871384 7278933 1191971..1192510 1 NC_011852.1 COG:OC;COG0526; thiol-disulfide interchange protein 1192510 dsbE 7278933 dsbE Haemophilus parasuis SH0165 thiol-disulfide interchange protein YP_002475759.1 1191971 D 557723 CDS YP_002475760.1 219871385 7278934 1192510..1192974 1 NC_011852.1 COG:O;COG3088; cytochrome C-type biogenesis protein 1192974 ccmH_1 7278934 ccmH_1 Haemophilus parasuis SH0165 cytochrome C-type biogenesis protein YP_002475760.1 1192510 D 557723 CDS YP_002475761.1 219871386 7278935 1192974..1193876 1 NC_011852.1 COG:O;COG4235; cytochrome C-type biogenesis protein, TPR repeat-containing protein 1193876 ccmH_2 7278935 ccmH_2 Haemophilus parasuis SH0165 cytochrome C-type biogenesis protein, TPR repeat-containing protein YP_002475761.1 1192974 D 557723 CDS YP_002475762.1 219871387 7278936 1193909..1194853 1 NC_011852.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1194853 miaA 7278936 miaA Haemophilus parasuis SH0165 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002475762.1 1193909 D 557723 CDS YP_002475763.1 219871388 7278937 1194908..1195189 1 NC_011852.1 COG:R;COG1923; RNA-binding protein Hfq 1195189 hfq 7278937 hfq Haemophilus parasuis SH0165 RNA-binding protein Hfq YP_002475763.1 1194908 D 557723 CDS YP_002475764.1 219871389 7278938 1195344..1196570 1 NC_011852.1 COG:R;COG2262; GTP-binding protein hflX 1196570 hflX 7278938 hflX Haemophilus parasuis SH0165 GTP-binding protein hflX YP_002475764.1 1195344 D 557723 CDS YP_002475765.1 219871390 7278939 1196627..1197301 1 NC_011852.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 1197301 gph 7278939 gph Haemophilus parasuis SH0165 phosphoglycolate phosphatase YP_002475765.1 1196627 D 557723 CDS YP_002475766.1 219871391 7278940 complement(1197756..1198643) 1 NC_011852.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 1198643 nanK 7278940 nanK Haemophilus parasuis SH0165 N-acetylmannosamine kinase YP_002475766.1 1197756 R 557723 CDS YP_002475767.1 219871392 7278941 complement(1198645..1199340) 1 NC_011852.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1199340 nanE 7278941 nanE Haemophilus parasuis SH0165 N-acetylmannosamine-6-phosphate 2-epimerase YP_002475767.1 1198645 R 557723 CDS YP_002475768.1 219871393 7278942 complement(1199530..1200438) 1 NC_011852.1 COG:Q;COG2313; indigoidine synthase A-like protein 1200438 idgA 7278942 idgA Haemophilus parasuis SH0165 indigoidine synthase A-like protein YP_002475768.1 1199530 R 557723 CDS YP_002475769.1 219871394 7278943 complement(1200431..1201534) 1 NC_011852.1 COG:G;COG0524; carbohydrate kinase-like protein 1201534 7278943 HAPS_1218 Haemophilus parasuis SH0165 carbohydrate kinase-like protein YP_002475769.1 1200431 R 557723 CDS YP_002475770.1 219871395 7278945 1202441..1203700 1 NC_011852.1 COG:F;COG1972; transport system nucleoside permease 1203700 7278945 HAPS_1220 Haemophilus parasuis SH0165 transport system nucleoside permease YP_002475770.1 1202441 D 557723 CDS YP_002475771.1 219871396 7278946 1203791..1204570 1 NC_011852.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1204570 deoC 7278946 deoC Haemophilus parasuis SH0165 deoxyribose-phosphate aldolase YP_002475771.1 1203791 D 557723 CDS YP_002475772.1 219871397 7278947 1204599..1205318 1 NC_011852.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 1205318 deoD 7278947 deoD Haemophilus parasuis SH0165 purine nucleoside phosphorylase YP_002475772.1 1204599 D 557723 CDS YP_002475773.1 219871398 7278948 complement(1206157..1206759) 1 NC_011852.1 COG:S;COG3102; hypothetical protein 1206759 7278948 HAPS_1223 Haemophilus parasuis SH0165 hypothetical protein YP_002475773.1 1206157 R 557723 CDS YP_002475774.1 219871399 7278949 1206877..1208523 1 NC_011852.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1208523 argS 7278949 argS Haemophilus parasuis SH0165 arginyl-tRNA synthetase YP_002475774.1 1206877 D 557723 CDS YP_002475775.1 219871400 7278952 complement(1209746..1210933) 1 NC_011852.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1210933 tuf 7278952 tuf Haemophilus parasuis SH0165 elongation factor Tu YP_002475775.1 1209746 R 557723 CDS YP_002475776.1 219871401 7278957 complement(1211686..1211805) 1 NC_011852.1 hypothetical protein 1211805 7278957 HAPS_1233 Haemophilus parasuis SH0165 hypothetical protein YP_002475776.1 1211686 R 557723 CDS YP_002475777.1 219871402 7278959 1211798..1212739 1 NC_011852.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1212739 coaA 7278959 coaA Haemophilus parasuis SH0165 pantothenate kinase YP_002475777.1 1211798 D 557723 CDS YP_002475778.1 219871403 7278958 1212742..1213449 1 NC_011852.1 COG:R;COG4123; phosphatidylserine synthase 1213449 pssA 7278958 pssA Haemophilus parasuis SH0165 phosphatidylserine synthase YP_002475778.1 1212742 D 557723 CDS YP_002475779.1 219871404 7278960 complement(1213543..1214505) 1 NC_011852.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1214505 lipA 7278960 lipA Haemophilus parasuis SH0165 lipoyl synthase YP_002475779.1 1213543 R 557723 CDS YP_002475780.1 219871405 7278961 complement(1214518..1215114) 1 NC_011852.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1215114 lipB 7278961 lipB Haemophilus parasuis SH0165 lipoate-protein ligase B YP_002475780.1 1214518 R 557723 CDS YP_002475781.1 219871406 7278962 complement(1215178..1215477) 1 NC_011852.1 COG:S;COG2921; hypothetical protein 1215477 7278962 HAPS_1237 Haemophilus parasuis SH0165 hypothetical protein YP_002475781.1 1215178 R 557723 CDS YP_002475782.1 219871407 7278963 complement(1215591..1216772) 1 NC_011852.1 COG:M;COG1686; D-alanyl-D-alanine carboxypeptidase 1216772 dacA 7278963 dacA Haemophilus parasuis SH0165 D-alanyl-D-alanine carboxypeptidase YP_002475782.1 1215591 R 557723 CDS YP_002475783.1 219871408 7278964 complement(1216787..1217779) 1 NC_011852.1 COG:M;COG0797; rare lipoprotein A 1217779 rlpA 7278964 rlpA Haemophilus parasuis SH0165 rare lipoprotein A YP_002475783.1 1216787 R 557723 CDS YP_002475784.1 219871409 7278965 complement(1217807..1218757) 1 NC_011852.1 COG:D;COG0772; rod-shape-determining protein RodA 1218757 rodA 7278965 rodA Haemophilus parasuis SH0165 rod-shape-determining protein RodA YP_002475784.1 1217807 R 557723 CDS YP_002475785.1 219871410 7278966 complement(1218933..1220867) 1 NC_011852.1 COG:M;COG0768; cell division protein FtsI 1220867 ftsI 7278966 ftsI Haemophilus parasuis SH0165 cell division protein FtsI YP_002475785.1 1218933 R 557723 CDS YP_002475786.1 219871411 7278967 complement(1220874..1221308) 1 NC_011852.1 COG:S;COG1576; SPOUT methyltransferase superfamily protein 1221308 7278967 HAPS_1242 Haemophilus parasuis SH0165 SPOUT methyltransferase superfamily protein YP_002475786.1 1220874 R 557723 CDS YP_002475787.1 219871412 7278968 complement(1221342..1221656) 1 NC_011852.1 COG:S;COG0799; plant Iojap-like protein 1221656 7278968 HAPS_1243 Haemophilus parasuis SH0165 plant Iojap-like protein YP_002475787.1 1221342 R 557723 CDS YP_002475788.1 219871413 7278971 1222256..1222966 1 NC_011852.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1222966 sfsA 7278971 sfsA Haemophilus parasuis SH0165 sugar fermentation stimulation protein A YP_002475788.1 1222256 D 557723 CDS YP_002475789.1 219871414 7278973 1223448..1223969 1 NC_011852.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1223969 hslV 7278973 hslV Haemophilus parasuis SH0165 ATP-dependent protease peptidase subunit YP_002475789.1 1223448 D 557723 CDS YP_002475790.1 219871415 7278974 1224059..1225381 1 NC_011852.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1225381 hslU 7278974 hslU Haemophilus parasuis SH0165 ATP-dependent protease ATP-binding subunit HslU YP_002475790.1 1224059 D 557723 CDS YP_002475791.1 219871416 7277881 1225513..1227222 1 NC_011852.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1227222 menD 7277881 menD Haemophilus parasuis SH0165 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_002475791.1 1225513 D 557723 CDS YP_002475792.1 219871417 7278044 1227261..1227989 1 NC_011852.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 1227989 yfbB 7278044 yfbB Haemophilus parasuis SH0165 acyl-CoA thioester hydrolase YfbB YP_002475792.1 1227261 D 557723 CDS YP_002475793.1 219871418 7278045 1227998..1228228 1 NC_011852.1 acetyl-CoA carboxylase subunit beta 1228228 accD 7278045 accD Haemophilus parasuis SH0165 acetyl-CoA carboxylase subunit beta YP_002475793.1 1227998 D 557723 CDS YP_002475794.1 219871419 7278046 complement(1228528..1229595) 1 NC_011852.1 COG:T;COG1702; phosphate starvation-inducible protein PhoH 1229595 phoH 7278046 phoH Haemophilus parasuis SH0165 phosphate starvation-inducible protein PhoH YP_002475794.1 1228528 R 557723 CDS YP_002475795.1 219871420 7278047 1229834..1230814 1 NC_011852.1 COG:H;COG4143; thiamine-binding periplasmic protein 1230814 tbpA 7278047 tbpA Haemophilus parasuis SH0165 thiamine-binding periplasmic protein YP_002475795.1 1229834 D 557723 CDS YP_002475796.1 219871421 7278048 complement(1230854..1233067) 1 NC_011852.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1233067 priA 7278048 priA Haemophilus parasuis SH0165 primosome assembly protein PriA YP_002475796.1 1230854 R 557723 CDS YP_002475797.1 219871422 7278049 complement(1233067..1233933) 1 NC_011852.1 COG:R;COG2962; DMT superfamily drug/metabolite transporter 1233933 7278049 HAPS_1256 Haemophilus parasuis SH0165 DMT superfamily drug/metabolite transporter YP_002475797.1 1233067 R 557723 CDS YP_002475798.1 219871423 7278050 complement(1233933..1234814) 1 NC_011852.1 COG:R;COG2962; DMT superfamily drug/metabolite transporter 1234814 7278050 HAPS_1257 Haemophilus parasuis SH0165 DMT superfamily drug/metabolite transporter YP_002475798.1 1233933 R 557723 CDS YP_002475799.1 219871424 7278051 complement(1235008..1236225) 1 NC_011852.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1236225 alaT 7278051 alaT Haemophilus parasuis SH0165 aminotransferase AlaT YP_002475799.1 1235008 R 557723 CDS YP_002475800.1 219871425 7278052 1236372..1237646 1 NC_011852.1 COG:HQ;COG1169; menaquinone-specific isochorismate synthase 1237646 menF 7278052 menF Haemophilus parasuis SH0165 menaquinone-specific isochorismate synthase YP_002475800.1 1236372 D 557723 CDS YP_002475801.1 219871426 7278053 1237938..1238660 1 NC_011852.1 COG:I;COG0671; phosphatidylglycerophosphatase B 1238660 pgpB 7278053 pgpB Haemophilus parasuis SH0165 phosphatidylglycerophosphatase B YP_002475801.1 1237938 D 557723 CDS YP_002475802.1 219871427 7278054 1238663..1239577 1 NC_011852.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1239577 nagK 7278054 nagK Haemophilus parasuis SH0165 N-acetyl-D-glucosamine kinase YP_002475802.1 1238663 D 557723 CDS YP_002475803.1 219871428 7278055 1239744..1240451 1 NC_011852.1 COG:R;COG0491; putative hydroxyacylglutathione hydrolase 1240451 gloB 7278055 gloB Haemophilus parasuis SH0165 putative hydroxyacylglutathione hydrolase YP_002475803.1 1239744 D 557723 CDS YP_002475804.1 219871429 7278056 1240608..1241276 1 NC_011852.1 COG:I;COG0020; undecaprenyl pyrophosphate synthetase 1241276 uppS 7278056 uppS Haemophilus parasuis SH0165 undecaprenyl pyrophosphate synthetase YP_002475804.1 1240608 D 557723 CDS YP_002475805.1 219871430 7278057 1241294..1242163 1 NC_011852.1 COG:I;COG0575; CDP-diglyceride pyrophosphorylase 1242163 cdsA 7278057 cdsA Haemophilus parasuis SH0165 CDP-diglyceride pyrophosphorylase YP_002475805.1 1241294 D 557723 CDS YP_002475806.1 219871431 7278058 1242173..1243492 1 NC_011852.1 COG:M;COG0750; putative zinc metalloprotease 1243492 yaeL 7278058 yaeL Haemophilus parasuis SH0165 putative zinc metalloprotease YP_002475806.1 1242173 D 557723 CDS YP_002475807.1 219871432 7278059 1243543..1245960 1 NC_011852.1 COG:M;COG4775; protective surface antigen D15 1245960 ompD15 7278059 ompD15 Haemophilus parasuis SH0165 protective surface antigen D15 YP_002475807.1 1243543 D 557723 CDS YP_002475808.1 219871433 7278060 1246035..1246838 1 NC_011852.1 COG:M;COG2825; outer membrane protein 26 1246838 omp26 7278060 omp26 Haemophilus parasuis SH0165 outer membrane protein 26 YP_002475808.1 1246035 D 557723 CDS YP_002475809.1 219871434 7278061 1246838..1247863 1 NC_011852.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1247863 lpxD 7278061 lpxD Haemophilus parasuis SH0165 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002475809.1 1246838 D 557723 CDS YP_002475810.1 219871435 7278062 1247882..1248349 1 NC_011852.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1248349 fabZ 7278062 fabZ Haemophilus parasuis SH0165 (3R)-hydroxymyristoyl-ACP dehydratase YP_002475810.1 1247882 D 557723 CDS YP_002475811.1 219871436 7278063 1248377..1249171 1 NC_011852.1 COG:M;COG1043; UDP-N-acetylglucosamine acyltransferase 1249171 lpxA 7278063 lpxA Haemophilus parasuis SH0165 UDP-N-acetylglucosamine acyltransferase YP_002475811.1 1248377 D 557723 CDS YP_002475812.1 219871437 7278064 1249562..1252006 1 NC_011852.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 1252006 thrA 7278064 thrA Haemophilus parasuis SH0165 bifunctional aspartokinase I/homoserine dehydrogenase I YP_002475812.1 1249562 D 557723 CDS YP_002475813.1 219871438 7278065 1252103..1253050 1 NC_011852.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1253050 thrB 7278065 thrB Haemophilus parasuis SH0165 homoserine kinase YP_002475813.1 1252103 D 557723 CDS YP_002475814.1 219871439 7278066 complement(1253142..1254263) 1 NC_011852.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 1254263 tyrA 7278066 tyrA Haemophilus parasuis SH0165 bifunctional chorismate mutase/prephenate dehydrogenase YP_002475814.1 1253142 R 557723 CDS YP_002475815.1 219871440 7278067 complement(1254265..1255326) 1 NC_011852.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1255326 aroF 7278067 aroF Haemophilus parasuis SH0165 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002475815.1 1254265 R 557723 CDS YP_002475816.1 219871441 7278068 complement(1255477..1256499) 1 NC_011852.1 COG:M;COG0859; ADP-heptose:LPS heptosyltransferase 1256499 opsX 7278068 opsX Haemophilus parasuis SH0165 ADP-heptose:LPS heptosyltransferase YP_002475816.1 1255477 R 557723 CDS YP_002475817.1 219871442 7278069 complement(1256508..1256846) 1 NC_011852.1 COG:P;COG2920; dissimilatory sulfite reductase subunit gamma 1256846 7278069 HAPS_1276 Haemophilus parasuis SH0165 dissimilatory sulfite reductase subunit gamma YP_002475817.1 1256508 R 557723 CDS YP_002475818.1 219871443 7278071 complement(1257967..1259415) 1 NC_011852.1 COG:E;COG1115; Na+/alanine symporter 1259415 7278071 HAPS_1278 Haemophilus parasuis SH0165 Na+/alanine symporter YP_002475818.1 1257967 R 557723 CDS YP_002475819.1 219871444 7278072 complement(1259618..1260595) 1 NC_011852.1 COG:R;COG2215; nickel/cobalt ABC transporter permease 1260595 rcnA 7278072 rcnA Haemophilus parasuis SH0165 nickel/cobalt ABC transporter permease YP_002475819.1 1259618 R 557723 CDS YP_002475820.1 219871445 7278073 complement(1260586..1261227) 1 NC_011852.1 COG:R;COG3683; nickel/cobalt ABC transporter periplasmic component 1261227 rcnB 7278073 rcnB Haemophilus parasuis SH0165 nickel/cobalt ABC transporter periplasmic component YP_002475820.1 1260586 R 557723 CDS YP_002475821.1 219871446 7278074 complement(1261904..1263937) 1 NC_011852.1 COG:E;COG0339; Zn-dependent oligopeptidase 1263937 prlC 7278074 prlC Haemophilus parasuis SH0165 Zn-dependent oligopeptidase YP_002475821.1 1261904 R 557723 CDS YP_002475822.1 219871447 7278075 1264119..1265285 1 NC_011852.1 COG:E;COG0077; bifunctional prephenate dehydratase/chorismate mutase 1265285 pheA 7278075 pheA Haemophilus parasuis SH0165 bifunctional prephenate dehydratase/chorismate mutase YP_002475822.1 1264119 D 557723 CDS YP_002475823.1 219871448 7278076 complement(1265316..1265978) 1 NC_011852.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1265978 ung 7278076 ung Haemophilus parasuis SH0165 uracil-DNA glycosylase YP_002475823.1 1265316 R 557723 CDS YP_002475824.1 219871449 7278077 1266174..1266557 1 NC_011852.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 1266557 grcA 7278077 grcA Haemophilus parasuis SH0165 autonomous glycyl radical cofactor GrcA YP_002475824.1 1266174 D 557723 CDS YP_002475825.1 219871450 7278078 complement(1266644..1267987) 1 NC_011852.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1267987 accC 7278078 accC Haemophilus parasuis SH0165 acetyl-CoA carboxylase biotin carboxylase subunit YP_002475825.1 1266644 R 557723 CDS YP_002475826.1 219871451 7278079 complement(1268063..1268533) 1 NC_011852.1 COG:I;COG0511; biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP) 1268533 accB 7278079 accB Haemophilus parasuis SH0165 biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP) YP_002475826.1 1268063 R 557723 CDS YP_002475827.1 219871452 7278080 1268599..1268754 1 NC_011852.1 hypothetical protein 1268754 7278080 HAPS_1287 Haemophilus parasuis SH0165 hypothetical protein YP_002475827.1 1268599 D 557723 CDS YP_002475828.1 219871453 7278081 complement(1268730..1269173) 1 NC_011852.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1269173 aroQ 7278081 aroQ Haemophilus parasuis SH0165 3-dehydroquinate dehydratase YP_002475828.1 1268730 R 557723 CDS YP_002475829.1 219871454 7278082 complement(1269333..1270340) 1 NC_011852.1 COG:H;COG0502; biotin synthase 1270340 bioB 7278082 bioB Haemophilus parasuis SH0165 biotin synthase YP_002475829.1 1269333 R 557723 CDS YP_002475830.1 219871455 7278083 complement(1270396..1271220) 1 NC_011852.1 COG:E;COG2171; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1271220 dapD 7278083 dapD Haemophilus parasuis SH0165 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002475830.1 1270396 R 557723 CDS YP_002475831.1 219871456 7278084 complement(1271198..1271320) 1 NC_011852.1 hypothetical protein 1271320 7278084 HAPS_1291 Haemophilus parasuis SH0165 hypothetical protein YP_002475831.1 1271198 R 557723 CDS YP_002475832.1 219871457 7278085 1271463..1271930 1 NC_011852.1 COG:R;COG1399; hypothetical protein 1271930 7278085 HAPS_1292 Haemophilus parasuis SH0165 hypothetical protein YP_002475832.1 1271463 D 557723 CDS YP_002475833.1 219871458 7278086 1271951..1272112 1 NC_011852.1 COG:J;COG0333; 50S ribosomal protein L32 1272112 rpmF 7278086 rpmF Haemophilus parasuis SH0165 50S ribosomal protein L32 YP_002475833.1 1271951 D 557723 CDS YP_002475834.1 219871459 7278087 1272169..1273164 1 NC_011852.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1273164 plsX 7278087 plsX Haemophilus parasuis SH0165 putative glycerol-3-phosphate acyltransferase PlsX YP_002475834.1 1272169 D 557723 CDS YP_002475835.1 219871460 7278088 1273450..1274466 1 NC_011852.1 COG:E;COG0160; diaminobutyrate--2-oxoglutarate aminotransferase 1274466 dat 7278088 dat Haemophilus parasuis SH0165 diaminobutyrate--2-oxoglutarate aminotransferase YP_002475835.1 1273450 D 557723 CDS YP_002475836.1 219871461 7278089 1274438..1275895 1 NC_011852.1 COG:E;COG0076; L-2,4-diaminobutyrate decarboxylase 1275895 ddc 7278089 ddc Haemophilus parasuis SH0165 L-2,4-diaminobutyrate decarboxylase YP_002475836.1 1274438 D 557723 CDS YP_002475837.1 219871462 7278090 1276156..1277037 1 NC_011852.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1277037 ppnK 7278090 ppnK Haemophilus parasuis SH0165 inorganic polyphosphate/ATP-NAD kinase YP_002475837.1 1276156 D 557723 CDS YP_002475838.1 219871463 7278091 complement(1277146..1277880) 1 NC_011852.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1277880 rph 7278091 rph Haemophilus parasuis SH0165 ribonuclease PH YP_002475838.1 1277146 R 557723 CDS YP_002475839.1 219871464 7278092 1277971..1278834 1 NC_011852.1 COG:S;COG1561; hypothetical protein 1278834 7278092 HAPS_1299 Haemophilus parasuis SH0165 hypothetical protein YP_002475839.1 1277971 D 557723 CDS YP_002475840.1 219871465 7278093 1278838..1279866 1 NC_011852.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1279866 murB 7278093 murB Haemophilus parasuis SH0165 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002475840.1 1278838 D 557723 CDS YP_002475841.1 219871466 7278094 1279873..1280634 1 NC_011852.1 COG:H;COG0340; bifunctional biotin operon repressor/biotin synthetase BirA 1280634 birA 7278094 birA Haemophilus parasuis SH0165 bifunctional biotin operon repressor/biotin synthetase BirA YP_002475841.1 1279873 D 557723 CDS YP_002475842.1 219871467 7278095 1280836..1281198 1 NC_011852.1 COG:S;COG2832; hypothetical protein 1281198 7278095 HAPS_1302 Haemophilus parasuis SH0165 hypothetical protein YP_002475842.1 1280836 D 557723 CDS YP_002475843.1 219871468 7278096 1281250..1281843 1 NC_011852.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 1281843 mogA 7278096 mogA Haemophilus parasuis SH0165 molybdenum cofactor biosynthesis protein MogA YP_002475843.1 1281250 D 557723 CDS YP_002475844.1 219871469 7278097 1281852..1282190 1 NC_011852.1 COG:E;COG0347; nitrogen regulatory protein P-II 1282190 glnB 7278097 glnB Haemophilus parasuis SH0165 nitrogen regulatory protein P-II YP_002475844.1 1281852 D 557723 CDS YP_002475845.1 219871470 7278098 1282199..1282687 1 NC_011852.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1282687 lspA 7278098 lspA Haemophilus parasuis SH0165 lipoprotein signal peptidase YP_002475845.1 1282199 D 557723 CDS YP_002475846.1 219871471 7278099 1282688..1283632 1 NC_011852.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1283632 ispH 7278099 ispH Haemophilus parasuis SH0165 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002475846.1 1282688 D 557723 CDS YP_002475847.1 219871472 7278100 1283632..1283871 1 NC_011852.1 COG:S;COG2938; hypothetical protein 1283871 7278100 HAPS_1307 Haemophilus parasuis SH0165 hypothetical protein YP_002475847.1 1283632 D 557723 CDS YP_002475848.1 219871473 7278101 1284198..1285172 1 NC_011852.1 COG:L;COG1194; A/G-specific DNA-adenine glycosylase 1285172 mutY 7278101 mutY Haemophilus parasuis SH0165 A/G-specific DNA-adenine glycosylase YP_002475848.1 1284198 D 557723 CDS YP_002475849.1 219871474 7278102 1285162..1285437 1 NC_011852.1 COG:CO;COG2924; hypothetical protein 1285437 yggX 7278102 yggX Haemophilus parasuis SH0165 hypothetical protein YP_002475849.1 1285162 D 557723 CDS YP_002475850.1 219871475 7278103 1285448..1286542 1 NC_011852.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 1286542 mltC 7278103 mltC Haemophilus parasuis SH0165 murein transglycosylase C YP_002475850.1 1285448 D 557723 CDS YP_002475851.1 219871476 7278104 complement(1286499..1286642) 1 NC_011852.1 hypothetical protein 1286642 7278104 HAPS_1311 Haemophilus parasuis SH0165 hypothetical protein YP_002475851.1 1286499 R 557723 CDS YP_002475852.1 219871477 7278107 complement(1287241..1288518) 1 NC_011852.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 1288518 glpC 7278107 glpC Haemophilus parasuis SH0165 sn-glycerol-3-phosphate dehydrogenase subunit C YP_002475852.1 1287241 R 557723 CDS YP_002475853.1 219871478 7278108 complement(1288520..1289803) 1 NC_011852.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 1289803 glpB 7278108 glpB Haemophilus parasuis SH0165 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_002475853.1 1288520 R 557723 CDS YP_002475854.1 219871479 7278109 complement(1289793..1291295) 1 NC_011852.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 1291295 glpA 7278109 glpA Haemophilus parasuis SH0165 sn-glycerol-3-phosphate dehydrogenase subunit A YP_002475854.1 1289793 R 557723 CDS YP_002475855.1 219871480 7278112 complement(1292521..1293480) 1 NC_011852.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1293480 rluC 7278112 rluC Haemophilus parasuis SH0165 23S rRNA pseudouridylate synthase C YP_002475855.1 1292521 R 557723 CDS YP_002475856.1 219871481 7278113 1293570..1294481 1 NC_011852.1 COG:M;COG0668; small-conductance mechanosensitive channel 1294481 mscS 7278113 mscS Haemophilus parasuis SH0165 small-conductance mechanosensitive channel YP_002475856.1 1293570 D 557723 CDS YP_002475857.1 219871482 7278114 complement(1294598..1295353) 1 NC_011852.1 COG:O;COG0501; Zn-dependent protease with chaperone function 1295353 htpX 7278114 htpX Haemophilus parasuis SH0165 Zn-dependent protease with chaperone function YP_002475857.1 1294598 R 557723 CDS YP_002475858.1 219871483 7278115 complement(1295420..1295947) 1 NC_011852.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 1295947 ppa 7278115 ppa Haemophilus parasuis SH0165 inorganic pyrophosphatase YP_002475858.1 1295420 R 557723 CDS YP_002475859.1 219871484 7278116 complement(1296082..1298934) 1 NC_011852.1 COG:KL;COG0553; superfamily II DNA/RNA helicase, SNF2 family, ATP-dependent 1298934 7278116 HAPS_1323 Haemophilus parasuis SH0165 superfamily II DNA/RNA helicase, SNF2 family, ATP-dependent YP_002475859.1 1296082 R 557723 CDS YP_002475860.1 219871485 7278117 complement(1298952..1300019) 1 NC_011852.1 COG:S;COG3177; filamentation induced by cAMP protein fic 1300019 fic 7278117 fic Haemophilus parasuis SH0165 filamentation induced by cAMP protein fic YP_002475860.1 1298952 R 557723 CDS YP_002475861.1 219871486 7278118 complement(1300179..1303583) 1 NC_011852.1 type III restriction protein, res subunit 1303583 7278118 HAPS_1325 Haemophilus parasuis SH0165 type III restriction protein, res subunit YP_002475861.1 1300179 R 557723 CDS YP_002475862.1 219871487 7278120 1307007..1308488 1 NC_011852.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1308488 ilvC 7278120 ilvC Haemophilus parasuis SH0165 ketol-acid reductoisomerase YP_002475862.1 1307007 D 557723 CDS YP_002475863.1 219871488 7278121 complement(1308983..1309990) 1 NC_011852.1 hypothetical protein 1309990 7278121 HAPS_1328 Haemophilus parasuis SH0165 hypothetical protein YP_002475863.1 1308983 R 557723 CDS YP_002475864.1 219871489 7278122 1310631..1310756 1 NC_011852.1 hypothetical protein 1310756 7278122 HAPS_1329 Haemophilus parasuis SH0165 hypothetical protein YP_002475864.1 1310631 D 557723 CDS YP_002475865.1 219871490 7278123 1310762..1310971 1 NC_011852.1 hypothetical protein 1310971 7278123 HAPS_1330 Haemophilus parasuis SH0165 hypothetical protein YP_002475865.1 1310762 D 557723 CDS YP_002475866.1 219871491 7278124 1311124..1311498 1 NC_011852.1 hypothetical protein 1311498 7278124 HAPS_1331 Haemophilus parasuis SH0165 hypothetical protein YP_002475866.1 1311124 D 557723 CDS YP_002475867.1 219871492 7277477 1318342..1319682 1 NC_011852.1 COG:ER;COG0591; sodium/proline symporter, proline permease 1319682 putP 7277477 putP Haemophilus parasuis SH0165 sodium/proline symporter, proline permease YP_002475867.1 1318342 D 557723 CDS YP_002475868.1 219871493 7277478 1319798..1323409 1 NC_011852.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1323409 putA 7277478 putA Haemophilus parasuis SH0165 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002475868.1 1319798 D 557723 CDS YP_002475869.1 219871494 7277479 1323727..1324704 1 NC_011852.1 ribonucleotide-diphosphate reductase subunit beta 1324704 nrdB 7277479 nrdB Haemophilus parasuis SH0165 ribonucleotide-diphosphate reductase subunit beta YP_002475869.1 1323727 D 557723 CDS YP_002475870.1 219871495 7277480 1324691..1326400 1 NC_011852.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1326400 nrdA 7277480 nrdA Haemophilus parasuis SH0165 ribonucleotide-diphosphate reductase subunit alpha YP_002475870.1 1324691 D 557723 CDS YP_002475871.1 219871496 7277481 1326455..1326574 1 NC_011852.1 hypothetical protein 1326574 7277481 HAPS_1343 Haemophilus parasuis SH0165 hypothetical protein YP_002475871.1 1326455 D 557723 CDS YP_002475872.1 219871497 7277482 1326588..1327637 1 NC_011852.1 COG:E;COG0687; spermidine/putrescine-binding periplasmic protein (SPBP) 1327637 potD 7277482 potD Haemophilus parasuis SH0165 spermidine/putrescine-binding periplasmic protein (SPBP) YP_002475872.1 1326588 D 557723 CDS YP_002475873.1 219871498 7277483 1327652..1328218 1 NC_011852.1 COG:S;COG1584; permease 1328218 yaaH 7277483 yaaH Haemophilus parasuis SH0165 permease YP_002475873.1 1327652 D 557723 CDS YP_002475874.1 219871499 7277484 1328505..1329020 1 NC_011852.1 COG:L;COG0632; holliday junction DNA helicase motor protein 1329020 ruvA 7277484 ruvA Haemophilus parasuis SH0165 holliday junction DNA helicase motor protein YP_002475874.1 1328505 D 557723 CDS YP_002475875.1 219871500 7277485 complement(1329142..1329612) 1 NC_011852.1 COG:S;COG3091; hypothetical protein 1329612 sprT 7277485 sprT Haemophilus parasuis SH0165 hypothetical protein YP_002475875.1 1329142 R 557723 CDS YP_002475876.1 219871501 7277486 complement(1329636..1330382) 1 NC_011852.1 COG:J;COG3719; ribonuclease 1330382 7277486 HAPS_1348 Haemophilus parasuis SH0165 ribonuclease YP_002475876.1 1329636 R 557723 CDS YP_002475877.1 219871502 7277487 1330565..1331515 1 NC_011852.1 COG:E;COG0031; cysteine synthase 1331515 cysK 7277487 cysK Haemophilus parasuis SH0165 cysteine synthase YP_002475877.1 1330565 D 557723 CDS YP_002475878.1 219871503 7277488 complement(1331579..1333123) 1 NC_011852.1 COG:R;COG0728; MviN virulence factor 1333123 mviN 7277488 mviN Haemophilus parasuis SH0165 MviN virulence factor YP_002475878.1 1331579 R 557723 CDS YP_002475879.1 219871504 7277489 1333391..1333654 1 NC_011852.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1333654 rpsT 7277489 rpsT Haemophilus parasuis SH0165 30S ribosomal protein S20 YP_002475879.1 1333391 D 557723 CDS YP_002475880.1 219871505 7277490 1333665..1333781 1 NC_011852.1 hypothetical protein 1333781 7277490 HAPS_1352 Haemophilus parasuis SH0165 hypothetical protein YP_002475880.1 1333665 D 557723 CDS YP_002475881.1 219871506 7277491 1333972..1335741 1 NC_011852.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1335741 mutL 7277491 mutL Haemophilus parasuis SH0165 DNA mismatch repair protein YP_002475881.1 1333972 D 557723 CDS YP_002475882.1 219871507 7277492 1335955..1338225 1 NC_011852.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 1338225 metE 7277492 metE Haemophilus parasuis SH0165 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_002475882.1 1335955 D 557723 CDS YP_002475883.1 219871508 7277493 1338468..1340147 1 NC_011852.1 COG:L;COG0497; DNA repair protein RecN 1340147 recN 7277493 recN Haemophilus parasuis SH0165 DNA repair protein RecN YP_002475883.1 1338468 D 557723 CDS YP_002475884.1 219871509 7277494 complement(1340213..1341151) 1 NC_011852.1 outer membrane lipoprotein A 1341151 lppA 7277494 lppA Haemophilus parasuis SH0165 outer membrane lipoprotein A YP_002475884.1 1340213 R 557723 CDS YP_002475885.1 219871510 7277495 complement(1341232..1341621) 1 NC_011852.1 COG:L;COG3676; ISMha3, family IS1595 1341621 7277495 HAPS_1357 Haemophilus parasuis SH0165 ISMha3, family IS1595 YP_002475885.1 1341232 R 557723 CDS YP_002475886.1 219871511 7277496 1341954..1342535 1 NC_011852.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 1342535 mutH 7277496 mutH Haemophilus parasuis SH0165 DNA mismatch repair protein YP_002475886.1 1341954 D 557723 CDS YP_002475887.1 219871512 7277497 complement(1342492..1342611) 1 NC_011852.1 hypothetical protein 1342611 7277497 HAPS_1359 Haemophilus parasuis SH0165 hypothetical protein YP_002475887.1 1342492 R 557723 CDS YP_002475888.1 219871513 7277498 1342622..1343350 1 NC_011852.1 COG:P;COG0861; tellurium resistance membrane protein TerC 1343350 terC 7277498 terC Haemophilus parasuis SH0165 tellurium resistance membrane protein TerC YP_002475888.1 1342622 D 557723 CDS YP_002475889.1 219871514 7277499 1343705..1344298 1 NC_011852.1 COG:H;COG3840; thiamin ABC transporter ATP-binding protein 1344298 thiQ 7277499 thiQ Haemophilus parasuis SH0165 thiamin ABC transporter ATP-binding protein YP_002475889.1 1343705 D 557723 CDS YP_002475890.1 219871515 7277500 1344449..1345081 1 NC_011852.1 COG:D;COG3087; cell division protein FtsN, sporulation domain-containing protein 1345081 fstN 7277500 fstN Haemophilus parasuis SH0165 cell division protein FtsN, sporulation domain-containing protein YP_002475890.1 1344449 D 557723 CDS YP_002475891.1 219871516 7277501 1345097..1345417 1 NC_011852.1 COG:S;COG4390; hypothetical protein 1345417 7277501 HAPS_1363 Haemophilus parasuis SH0165 hypothetical protein YP_002475891.1 1345097 D 557723 CDS YP_002475892.1 219871517 7277502 complement(1345494..1346267) 1 NC_011852.1 TobB energy transducing protein 1346267 tonB 7277502 tonB Haemophilus parasuis SH0165 TobB energy transducing protein YP_002475892.1 1345494 R 557723 CDS YP_002475893.1 219871518 7277503 complement(1346267..1346653) 1 NC_011852.1 COG:U;COG0848; TonB system transport protein ExbD type-2/biopolymer transport protein 1346653 exbD 7277503 exbD Haemophilus parasuis SH0165 TonB system transport protein ExbD type-2/biopolymer transport protein YP_002475893.1 1346267 R 557723 CDS YP_002475894.1 219871519 7277504 complement(1346696..1347148) 1 NC_011852.1 COG:U;COG0811; biopolymer transport protein ExbB 1347148 exbB 7277504 exbB Haemophilus parasuis SH0165 biopolymer transport protein ExbB YP_002475894.1 1346696 R 557723 CDS YP_002475895.1 219871520 7277505 1347316..1347642 1 NC_011852.1 COG:P;COG0607; rhodanese-related sulfur transferase 1347642 pspE 7277505 pspE Haemophilus parasuis SH0165 rhodanese-related sulfur transferase YP_002475895.1 1347316 D 557723 CDS YP_002475896.1 219871521 7277506 1347704..1348759 1 NC_011852.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1348759 sohB 7277506 sohB Haemophilus parasuis SH0165 putative periplasmic protease YP_002475896.1 1347704 D 557723 CDS YP_002475897.1 219871522 7277507 1348978..1349955 1 NC_011852.1 COG:J;COG0042; tRNA-dihydrouridine synthase B 1349955 dusB 7277507 dusB Haemophilus parasuis SH0165 tRNA-dihydrouridine synthase B YP_002475897.1 1348978 D 557723 CDS YP_002475898.1 219871523 7277508 1349972..1350268 1 NC_011852.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 1350268 fis 7277508 fis Haemophilus parasuis SH0165 DNA-binding protein Fis YP_002475898.1 1349972 D 557723 CDS YP_002475899.1 219871524 7277509 1350580..1351353 1 NC_011852.1 COG:H;COG2226; ubiquinone/menaquinone biosynthesis methyltransferase 1351353 ubiE 7277509 ubiE Haemophilus parasuis SH0165 ubiquinone/menaquinone biosynthesis methyltransferase YP_002475899.1 1350580 D 557723 CDS YP_002475900.1 219871525 7277510 1351356..1351982 1 NC_011852.1 similar to unknown protein YigP of Escherichia coli, SCP-2 sterol transfer family containing domain involved in binding sterols; COG:S;COG3165; YigP-like protein 1351982 yigP 7277510 yigP Haemophilus parasuis SH0165 YigP-like protein YP_002475900.1 1351356 D 557723 CDS YP_002475901.1 219871526 7277511 1352044..1353693 1 NC_011852.1 COG:R;COG0661; ubiquinone biosynthesis protein ubiB 1353693 ubiB 7277511 ubiB Haemophilus parasuis SH0165 ubiquinone biosynthesis protein ubiB YP_002475901.1 1352044 D 557723 CDS YP_002475902.1 219871527 7277512 complement(1354254..1355522) 1 NC_011852.1 COG:D;COG0037; cell-cycle protein MesJ 1355522 mesJ 7277512 mesJ Haemophilus parasuis SH0165 cell-cycle protein MesJ YP_002475902.1 1354254 R 557723 CDS YP_002475903.1 219871528 7277513 complement(1355531..1355965) 1 NC_011852.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1355965 dtd 7277513 dtd Haemophilus parasuis SH0165 D-tyrosyl-tRNA(Tyr) deacylase YP_002475903.1 1355531 R 557723 CDS YP_002475904.1 219871529 7277514 complement(1355962..1356810) 1 NC_011852.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 1356810 rbn 7277514 rbn Haemophilus parasuis SH0165 ribonuclease BN YP_002475904.1 1355962 R 557723 CDS YP_002475905.1 219871530 7277515 1356856..1356987 1 NC_011852.1 hypothetical protein 1356987 7277515 HAPS_1377 Haemophilus parasuis SH0165 hypothetical protein YP_002475905.1 1356856 D 557723 CDS YP_002475906.1 219871531 7277516 complement(1357029..1359344) 1 NC_011852.1 putative extracellular serine protease (autotransporter) 1359344 espP 7277516 espP Haemophilus parasuis SH0165 putative extracellular serine protease (autotransporter) YP_002475906.1 1357029 R 557723 CDS YP_002475907.1 219871532 7277517 complement(1359565..1360860) 1 NC_011852.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1360860 purD 7277517 purD Haemophilus parasuis SH0165 phosphoribosylamine--glycine ligase YP_002475907.1 1359565 R 557723 CDS YP_002475908.1 219871533 7277518 1361050..1362300 1 NC_011852.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1362300 proA 7277518 proA Haemophilus parasuis SH0165 gamma-glutamyl phosphate reductase YP_002475908.1 1361050 D 557723 CDS YP_002475909.1 219871534 7277519 1362485..1364827 1 NC_011852.1 putative extracellular serine protease (autotransporter) 1364827 espP 7277519 espP Haemophilus parasuis SH0165 putative extracellular serine protease (autotransporter) YP_002475909.1 1362485 D 557723 CDS YP_002475910.1 219871535 7277520 1365035..1366705 1 NC_011852.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1366705 7277520 HAPS_1382 Haemophilus parasuis SH0165 putative ABC transporter ATP-binding protein YP_002475910.1 1365035 D 557723 CDS YP_002475911.1 219871536 7277521 1366802..1368172 1 NC_011852.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1368172 gor 7277521 gor Haemophilus parasuis SH0165 glutathione reductase YP_002475911.1 1366802 D 557723 CDS YP_002475912.1 219871537 7277522 1368195..1368842 1 NC_011852.1 hypothetical protein 1368842 7277522 HAPS_1384 Haemophilus parasuis SH0165 hypothetical protein YP_002475912.1 1368195 D 557723 CDS YP_002475913.1 219871538 7277523 complement(1368873..1369487) 1 NC_011852.1 COG:O;COG0602; anaerobic ribonucleotide reductase activating protein NrdG 1369487 nrdG 7277523 nrdG Haemophilus parasuis SH0165 anaerobic ribonucleotide reductase activating protein NrdG YP_002475913.1 1368873 R 557723 CDS YP_002475914.1 219871539 7277524 complement(1369487..1369909) 1 NC_011852.1 COG:H;COG0720; 6-pyruvoyl tetrahydrobiopterin synthase 1369909 pts 7277524 pts Haemophilus parasuis SH0165 6-pyruvoyl tetrahydrobiopterin synthase YP_002475914.1 1369487 R 557723 CDS YP_002475915.1 219871540 7277525 complement(1369902..1370561) 1 NC_011852.1 COG:R;COG0603; queuosine biosynthesis protein QueC 1370561 queC 7277525 queC Haemophilus parasuis SH0165 queuosine biosynthesis protein QueC YP_002475915.1 1369902 R 557723 CDS YP_002475916.1 219871541 7277526 1370843..1371715 1 NC_011852.1 COG:R;COG1741; Pirin-like protein 1371715 pirA 7277526 pirA Haemophilus parasuis SH0165 Pirin-like protein YP_002475916.1 1370843 D 557723 CDS YP_002475917.1 219871542 7277527 1372066..1373364 1 NC_011852.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 1373364 pepB 7277527 pepB Haemophilus parasuis SH0165 aminopeptidase B YP_002475917.1 1372066 D 557723 CDS YP_002475918.1 219871543 7277528 1373419..1373862 1 NC_011852.1 COG:K;COG1959; transcriptional regulator 1373862 7277528 HAPS_1390 Haemophilus parasuis SH0165 transcriptional regulator YP_002475918.1 1373419 D 557723 CDS YP_002475919.1 219871544 7277529 complement(1373919..1374497) 1 NC_011852.1 COG:U;COG0805; twin-arginine translocase subunit, sec-independent protein export TatC 1374497 tatC 7277529 tatC Haemophilus parasuis SH0165 twin-arginine translocase subunit, sec-independent protein export TatC YP_002475919.1 1373919 R 557723 CDS YP_002475920.1 219871545 7277530 complement(1374671..1375219) 1 NC_011852.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 1375219 tatB 7277530 tatB Haemophilus parasuis SH0165 sec-independent translocase YP_002475920.1 1374671 R 557723 CDS YP_002475921.1 219871546 7277531 complement(1375223..1375447) 1 NC_011852.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 1375447 tatA 7277531 tatA Haemophilus parasuis SH0165 twin arginine translocase protein A YP_002475921.1 1375223 R 557723 CDS YP_002475922.1 219871547 7277532 1375790..1377430 1 NC_011852.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 1377430 yidC 7277532 yidC Haemophilus parasuis SH0165 putative inner membrane protein translocase component YidC YP_002475922.1 1375790 D 557723 CDS YP_002475923.1 219871548 7277533 1377440..1378228 1 NC_011852.1 COG:QR;COG0500; SAM-dependent methyltransferase, SmtA 1378228 smtA 7277533 smtA Haemophilus parasuis SH0165 SAM-dependent methyltransferase, SmtA YP_002475923.1 1377440 D 557723 CDS YP_002475924.1 219871549 7277534 1378272..1378784 1 NC_011852.1 outer membrane protein 18/16 1378784 omp18/16 7277534 omp18/16 Haemophilus parasuis SH0165 outer membrane protein 18/16 YP_002475924.1 1378272 D 557723 CDS YP_002475925.1 219871550 7277543 1385263..1386156 1 NC_011852.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1386156 xerD 7277543 xerD Haemophilus parasuis SH0165 site-specific tyrosine recombinase XerD YP_002475925.1 1385263 D 557723 CDS YP_002475926.1 219871551 7277544 1386158..1386451 1 NC_011852.1 hypothetical protein 1386451 7277544 HAPS_1406 Haemophilus parasuis SH0165 hypothetical protein YP_002475926.1 1386158 D 557723 CDS YP_002475927.1 219871552 7277545 complement(1386530..1387168) 1 NC_011852.1 COG:LR;COG0494; ADP-ribose pyrophosphatase 1387168 adpP 7277545 adpP Haemophilus parasuis SH0165 ADP-ribose pyrophosphatase YP_002475927.1 1386530 R 557723 CDS YP_002475928.1 219871553 7277546 complement(1387178..1387597) 1 NC_011852.1 COG:S;COG3223; phosphate-starvation-inducible protein PsiE 1387597 psiE 7277546 psiE Haemophilus parasuis SH0165 phosphate-starvation-inducible protein PsiE YP_002475928.1 1387178 R 557723 CDS YP_002475929.1 219871554 7277547 complement(1387605..1388336) 1 NC_011852.1 COG:H;COG2091; phosphopantetheinyl transferase 1388336 yieE 7277547 yieE Haemophilus parasuis SH0165 phosphopantetheinyl transferase YP_002475929.1 1387605 R 557723 CDS YP_002475930.1 219871555 7277548 complement(1388428..1388796) 1 NC_011852.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1388796 rplL 7277548 rplL Haemophilus parasuis SH0165 50S ribosomal protein L7/L12 YP_002475930.1 1388428 R 557723 CDS YP_002475931.1 219871556 7277549 complement(1388854..1389345) 1 NC_011852.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1389345 rplJ 7277549 rplJ Haemophilus parasuis SH0165 50S ribosomal protein L10 YP_002475931.1 1388854 R 557723 CDS YP_002475932.1 219871557 7277550 complement(1389746..1390213) 1 NC_011852.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1390213 coaD 7277550 coaD Haemophilus parasuis SH0165 phosphopantetheine adenylyltransferase YP_002475932.1 1389746 R 557723 CDS YP_002475933.1 219871558 7277551 complement(1390215..1391498) 1 NC_011852.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 1391498 kdtA 7277551 kdtA Haemophilus parasuis SH0165 3-deoxy-D-manno-octulosonic-acid transferase YP_002475933.1 1390215 R 557723 CDS YP_002475934.1 219871559 7277553 complement(1391508..1394984) 1 NC_011852.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1394984 dnaE 7277553 dnaE Haemophilus parasuis SH0165 DNA polymerase III subunit alpha YP_002475934.1 1391508 R 557723 CDS YP_002475935.1 219871560 7277160 complement(1395006..1395518) 1 NC_011852.1 hypothetical protein 1395518 7277160 HAPS_1415 Haemophilus parasuis SH0165 hypothetical protein YP_002475935.1 1395006 R 557723 CDS YP_002475936.1 219871561 7277161 complement(1395519..1396454) 1 NC_011852.1 putative amino-acid ABC transporter ATP-binding protein 1396454 7277161 HAPS_1416 Haemophilus parasuis SH0165 putative amino-acid ABC transporter ATP-binding protein YP_002475936.1 1395519 R 557723 CDS YP_002475937.1 219871562 7277162 complement(1396565..1397632) 1 NC_011852.1 COG:R;COG0795; permease 1397632 yigQ 7277162 yigQ Haemophilus parasuis SH0165 permease YP_002475937.1 1396565 R 557723 CDS YP_002475938.1 219871563 7277163 complement(1397629..1398729) 1 NC_011852.1 COG:R;COG0795; permease 1398729 yjgP 7277163 yjgP Haemophilus parasuis SH0165 permease YP_002475938.1 1397629 R 557723 CDS YP_002475939.1 219871564 7277164 1399076..1400572 1 NC_011852.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1400572 pepA 7277164 pepA Haemophilus parasuis SH0165 leucyl aminopeptidase YP_002475939.1 1399076 D 557723 CDS YP_002475940.1 219871565 7277165 1400773..1402152 1 NC_011852.1 COG:O;COG0826; collagenase prtC/related protease involved in cellular process and singaling 1402152 prtC 7277165 prtC Haemophilus parasuis SH0165 collagenase prtC/related protease involved in cellular process and singaling YP_002475940.1 1400773 D 557723 CDS YP_002475941.1 219871566 7277166 1402291..1404318 1 NC_011852.1 COG:O;COG3590; neutral endopeptidase 1404318 pepO 7277166 pepO Haemophilus parasuis SH0165 neutral endopeptidase YP_002475941.1 1402291 D 557723 CDS YP_002475942.1 219871567 7277167 1404422..1405279 1 NC_011852.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1405279 menB 7277167 menB Haemophilus parasuis SH0165 naphthoate synthase YP_002475942.1 1404422 D 557723 CDS YP_002475943.1 219871568 7277170 complement(1407004..1407591) 1 NC_011852.1 COG:I;COG1182; FMN-dependent NADH-azoreductase 1407591 azoR 7277170 azoR Haemophilus parasuis SH0165 FMN-dependent NADH-azoreductase YP_002475943.1 1407004 R 557723 CDS YP_002475944.1 219871569 7277172 complement(1408269..1408436) 1 NC_011852.1 hypothetical protein 1408436 7277172 HAPS_1427 Haemophilus parasuis SH0165 hypothetical protein YP_002475944.1 1408269 R 557723 CDS YP_002475945.1 219871570 7277173 complement(1408656..1409042) 1 NC_011852.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1409042 rplQ 7277173 rplQ Haemophilus parasuis SH0165 50S ribosomal protein L17 YP_002475945.1 1408656 R 557723 CDS YP_002475946.1 219871571 7277174 complement(1409078..1410067) 1 NC_011852.1 COG:K;COG0202; DNA-directed RNA polymerase subunit alpha 1410067 rpoA 7277174 rpoA Haemophilus parasuis SH0165 DNA-directed RNA polymerase subunit alpha YP_002475946.1 1409078 R 557723 CDS YP_002475947.1 219871572 7277175 complement(1410099..1410719) 1 NC_011852.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1410719 rpsD 7277175 rpsD Haemophilus parasuis SH0165 30S ribosomal protein S4 YP_002475947.1 1410099 R 557723 CDS YP_002475948.1 219871573 7277176 complement(1410748..1411137) 1 NC_011852.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1411137 rpsK 7277176 rpsK Haemophilus parasuis SH0165 30S ribosomal protein S11 YP_002475948.1 1410748 R 557723 CDS YP_002475949.1 219871574 7277177 complement(1411154..1411510) 1 NC_011852.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1411510 rpsM 7277177 rpsM Haemophilus parasuis SH0165 30S ribosomal protein S13 YP_002475949.1 1411154 R 557723 CDS YP_002475950.1 219871575 7277178 complement(1411649..1411762) 1 NC_011852.1 COG:J;COG0257; 50S ribosomal protein L36 1411762 rpmJ 7277178 rpmJ Haemophilus parasuis SH0165 50S ribosomal protein L36 YP_002475950.1 1411649 R 557723 CDS YP_002475951.1 219871576 7277179 complement(1411787..1413109) 1 NC_011852.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1413109 secY 7277179 secY Haemophilus parasuis SH0165 preprotein translocase subunit SecY YP_002475951.1 1411787 R 557723 CDS YP_002475952.1 219871577 7277180 complement(1413113..1413547) 1 NC_011852.1 late assembly protein; 50S ribosomal protein L15 1413547 rplO 7277180 rplO Haemophilus parasuis SH0165 50S ribosomal protein L15 YP_002475952.1 1413113 R 557723 CDS YP_002475953.1 219871578 7277181 complement(1413552..1413731) 1 NC_011852.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1413731 rpmD 7277181 rpmD Haemophilus parasuis SH0165 50S ribosomal protein L30 YP_002475953.1 1413552 R 557723 CDS YP_002475954.1 219871579 7277182 complement(1413738..1414238) 1 NC_011852.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1414238 rpsE 7277182 rpsE Haemophilus parasuis SH0165 30S ribosomal protein S5 YP_002475954.1 1413738 R 557723 CDS YP_002475955.1 219871580 7277183 complement(1414253..1414606) 1 NC_011852.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1414606 rplR 7277183 rplR Haemophilus parasuis SH0165 50S ribosomal protein L18 YP_002475955.1 1414253 R 557723 CDS YP_002475956.1 219871581 7277184 complement(1414621..1415154) 1 NC_011852.1 COG:J;COG0097; 50S ribosomal protein L6 1415154 rplF 7277184 rplF Haemophilus parasuis SH0165 50S ribosomal protein L6 YP_002475956.1 1414621 R 557723 CDS YP_002475957.1 219871582 7277185 complement(1415171..1415563) 1 NC_011852.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1415563 rpsH 7277185 rpsH Haemophilus parasuis SH0165 30S ribosomal protein S8 YP_002475957.1 1415171 R 557723 CDS YP_002475958.1 219871583 7277186 complement(1415600..1415905) 1 NC_011852.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1415905 rpsN 7277186 rpsN Haemophilus parasuis SH0165 30S ribosomal protein S14 YP_002475958.1 1415600 R 557723 CDS YP_002475959.1 219871584 7277187 complement(1415917..1416456) 1 NC_011852.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1416456 rplE 7277187 rplE Haemophilus parasuis SH0165 50S ribosomal protein L5 YP_002475959.1 1415917 R 557723 CDS YP_002475960.1 219871585 7277188 complement(1416474..1416785) 1 NC_011852.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1416785 rplX 7277188 rplX Haemophilus parasuis SH0165 50S ribosomal protein L24 YP_002475960.1 1416474 R 557723 CDS YP_002475961.1 219871586 7277189 complement(1416798..1417112) 1 NC_011852.1 COG:J;COG0093; 50S ribosomal protein L14 1417112 rplN 7277189 rplN Haemophilus parasuis SH0165 50S ribosomal protein L14 YP_002475961.1 1416798 R 557723 CDS YP_002475962.1 219871587 7277193 complement(1422558..1424804) 1 NC_011852.1 hypothetical protein 1424804 7277193 HAPS_1448 Haemophilus parasuis SH0165 hypothetical protein YP_002475962.1 1422558 R 557723 CDS YP_002475963.1 219871588 7277194 complement(1424977..1425579) 1 NC_011852.1 hypothetical protein 1425579 7277194 HAPS_1449 Haemophilus parasuis SH0165 hypothetical protein YP_002475963.1 1424977 R 557723 CDS YP_002475964.1 219871589 7277195 1425715..1426401 1 NC_011852.1 COG:M;COG1876; peptidase M15B 1426401 vanY 7277195 vanY Haemophilus parasuis SH0165 peptidase M15B YP_002475964.1 1425715 D 557723 CDS YP_002475965.1 219871590 7277196 complement(1426427..1427836) 1 NC_011852.1 COG:R;COG1123; ABC transporter ATP-binding protein 1427836 yejF 7277196 yejF Haemophilus parasuis SH0165 ABC transporter ATP-binding protein YP_002475965.1 1426427 R 557723 CDS YP_002475966.1 219871591 7277197 complement(1427907..1428689) 1 NC_011852.1 COG:EP;COG1173; Nickel transport system permease protein nikC 1428689 nikC 7277197 nikC Haemophilus parasuis SH0165 Nickel transport system permease protein nikC YP_002475966.1 1427907 R 557723 CDS YP_002475967.1 219871592 7277198 complement(1428686..1429465) 1 NC_011852.1 COG:EP;COG0601; Nickel transport system permease protein nikB 1429465 nikB 7277198 nikB Haemophilus parasuis SH0165 Nickel transport system permease protein nikB YP_002475967.1 1428686 R 557723 CDS YP_002475968.1 219871593 7277199 complement(1429737..1431320) 1 NC_011852.1 COG:E;COG0747; Nickel-binding periplasmic protein nikA 1431320 nikA 7277199 nikA Haemophilus parasuis SH0165 Nickel-binding periplasmic protein nikA YP_002475968.1 1429737 R 557723 CDS YP_002475969.1 219871594 7277200 complement(1431439..1432206) 1 NC_011852.1 COG:R;COG2005; molybdenum transport protein 1432206 modE 7277200 modE Haemophilus parasuis SH0165 molybdenum transport protein YP_002475969.1 1431439 R 557723 CDS YP_002475970.1 219871595 7277201 1432450..1433235 1 NC_011852.1 COG:P;COG0725; molybdate-binding periplasmic protein, ABC transporter 1433235 modA 7277201 modA Haemophilus parasuis SH0165 molybdate-binding periplasmic protein, ABC transporter YP_002475970.1 1432450 D 557723 CDS YP_002475971.1 219871596 7277202 complement(1433397..1433921) 1 NC_011852.1 hypothetical protein 1433921 7277202 HAPS_1457 Haemophilus parasuis SH0165 hypothetical protein YP_002475971.1 1433397 R 557723 CDS YP_002475972.1 219871597 7277203 1434011..1434862 1 NC_011852.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1434862 thyA 7277203 thyA Haemophilus parasuis SH0165 thymidylate synthase YP_002475972.1 1434011 D 557723 CDS YP_002475973.1 219871598 7277207 complement(1435412..1435996) 1 NC_011852.1 hypothetical protein 1435996 7277207 HAPS_1462 Haemophilus parasuis SH0165 hypothetical protein YP_002475973.1 1435412 R 557723 CDS YP_002475974.1 219871599 7277208 1436173..1437030 1 NC_011852.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1437030 purC 7277208 purC Haemophilus parasuis SH0165 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002475974.1 1436173 D 557723 CDS YP_002475975.1 219871600 7277209 1437258..1437932 1 NC_011852.1 COG:S;COG1738; hypothetical protein 1437932 7277209 HAPS_1464 Haemophilus parasuis SH0165 hypothetical protein YP_002475975.1 1437258 D 557723 CDS YP_002475976.1 219871601 7277210 complement(1437976..1439430) 1 NC_011852.1 COG:E;COG2195; aminoacyl-histidine dipeptidase 1439430 pepD 7277210 pepD Haemophilus parasuis SH0165 aminoacyl-histidine dipeptidase YP_002475976.1 1437976 R 557723 CDS YP_002475977.1 219871602 7277211 1439611..1440090 1 NC_011852.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 1440090 gpt 7277211 gpt Haemophilus parasuis SH0165 xanthine-guanine phosphoribosyltransferase YP_002475977.1 1439611 D 557723 CDS YP_002475978.1 219871603 7277212 complement(1440186..1441157) 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 1441157 7277212 HAPS_1467 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002475978.1 1440186 R 557723 CDS YP_002475979.1 219871604 7277213 1441414..1442124 1 NC_011852.1 COG:S;COG4947; putative esterase 1442124 7277213 HAPS_1468 Haemophilus parasuis SH0165 putative esterase YP_002475979.1 1441414 D 557723 CDS YP_002475980.1 219871605 7277214 1442162..1443421 1 NC_011852.1 COG:E;COG0019; diaminopimelate decarboxylase 1443421 lysA 7277214 lysA Haemophilus parasuis SH0165 diaminopimelate decarboxylase YP_002475980.1 1442162 D 557723 CDS YP_002475981.1 219871606 7277215 1443440..1444654 1 NC_011852.1 COG:E;COG0814; tryptophan-specific transport protein 1444654 mtr 7277215 mtr Haemophilus parasuis SH0165 tryptophan-specific transport protein YP_002475981.1 1443440 D 557723 CDS YP_002475982.1 219871607 7277216 1444736..1447297 1 NC_011852.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1447297 mutS 7277216 mutS Haemophilus parasuis SH0165 DNA mismatch repair protein MutS YP_002475982.1 1444736 D 557723 CDS YP_002475983.1 219871608 7277217 1447576..1448316 1 NC_011852.1 putative metal-activated pyridoxal enzyme 1448316 7277217 HAPS_1472 Haemophilus parasuis SH0165 putative metal-activated pyridoxal enzyme YP_002475983.1 1447576 D 557723 CDS YP_002475984.1 219871609 7277218 complement(1448494..1449873) 1 NC_011852.1 COG:O;COG0265; periplasmic serine protease do/hhoA-like 1449873 htrA 7277218 htrA Haemophilus parasuis SH0165 periplasmic serine protease do/hhoA-like YP_002475984.1 1448494 R 557723 CDS YP_002475985.1 219871610 7277219 1450176..1451774 1 NC_011852.1 COG:T;COG1966; carbon starvation protein A, membrane protein 1451774 cstA 7277219 cstA Haemophilus parasuis SH0165 carbon starvation protein A, membrane protein YP_002475985.1 1450176 D 557723 CDS YP_002475986.1 219871611 7277158 complement(1451979..1452863) 1 NC_011852.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1452863 prmA 7277158 prmA Haemophilus parasuis SH0165 50S ribosomal protein L11 methyltransferase YP_002475986.1 1451979 R 557723 CDS YP_002475987.1 219871612 7277220 complement(1454074..1454580) 1 NC_011852.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1454580 secB 7277220 secB Haemophilus parasuis SH0165 preprotein translocase subunit SecB YP_002475987.1 1454074 R 557723 CDS YP_002475988.1 219871613 7277882 complement(1454609..1455061) 1 NC_011852.1 COG:P;COG0607; putative rhodanese-related sulfurtransferase 1455061 7277882 HAPS_1478 Haemophilus parasuis SH0165 putative rhodanese-related sulfurtransferase YP_002475988.1 1454609 R 557723 CDS YP_002475989.1 219871614 7277883 complement(1455164..1456459) 1 NC_011852.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1456459 tig 7277883 tig Haemophilus parasuis SH0165 trigger factor YP_002475989.1 1455164 R 557723 CDS YP_002475990.1 219871615 7277884 complement(1457073..1457243) 1 NC_011852.1 hypothetical protein 1457243 7277884 HAPS_1480 Haemophilus parasuis SH0165 hypothetical protein YP_002475990.1 1457073 R 557723 CDS YP_002475991.1 219871616 7277887 1458748..1459932 1 NC_011852.1 nicotinate phosphoribosyltransferase 1459932 pncB 7277887 pncB Haemophilus parasuis SH0165 nicotinate phosphoribosyltransferase YP_002475991.1 1458748 D 557723 CDS YP_002475992.1 219871617 7277888 complement(1460012..1460818) 1 NC_011852.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1460818 map 7277888 map Haemophilus parasuis SH0165 methionine aminopeptidase YP_002475992.1 1460012 R 557723 CDS YP_002475993.1 219871618 7277889 complement(1460920..1462752) 1 NC_011852.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1462752 glmS 7277889 glmS Haemophilus parasuis SH0165 glucosamine--fructose-6-phosphate aminotransferase YP_002475993.1 1460920 R 557723 CDS YP_002475994.1 219871619 7277890 complement(1462786..1463472) 1 NC_011852.1 COG:KG;COG1349; sugar metabolism within DeoR family transcriptional regulator 1463472 7277890 HAPS_1486 Haemophilus parasuis SH0165 sugar metabolism within DeoR family transcriptional regulator YP_002475994.1 1462786 R 557723 CDS YP_002475995.1 219871620 7277891 complement(1463680..1464003) 1 NC_011852.1 COG:E;COG1687; branched-chain amino acid transport 1464003 7277891 HAPS_1487 Haemophilus parasuis SH0165 branched-chain amino acid transport YP_002475995.1 1463680 R 557723 CDS YP_002475996.1 219871621 7277893 complement(1466074..1466259) 1 NC_011852.1 hypothetical protein 1466259 7277893 HAPS_1489 Haemophilus parasuis SH0165 hypothetical protein YP_002475996.1 1466074 R 557723 CDS YP_002475997.1 219871622 7277895 complement(1466642..1467043) 1 NC_011852.1 COG:S;COG3111; putative outer membrane protein 1467043 ygiW 7277895 ygiW Haemophilus parasuis SH0165 putative outer membrane protein YP_002475997.1 1466642 R 557723 CDS YP_002475998.1 219871623 7277896 complement(1467327..1469408) 1 NC_011852.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1469408 recG 7277896 recG Haemophilus parasuis SH0165 ATP-dependent DNA helicase RecG YP_002475998.1 1467327 R 557723 CDS YP_002475999.1 219871624 7277897 complement(1469521..1470726) 1 NC_011852.1 COG:S;COG2850; exodeoxyribonuclease VII large subunit 1470726 xseA 7277897 xseA Haemophilus parasuis SH0165 exodeoxyribonuclease VII large subunit YP_002475999.1 1469521 R 557723 CDS YP_002476000.1 219871625 7277898 complement(1470802..1471590) 1 NC_011852.1 COG:S;COG4285; biotin apo-protein ligase 1471590 birA 7277898 birA Haemophilus parasuis SH0165 biotin apo-protein ligase YP_002476000.1 1470802 R 557723 CDS YP_002476001.1 219871626 7277899 1471674..1472240 1 NC_011852.1 COG:R;COG1268; biotin biosynthesis protein BioY 1472240 bioY 7277899 bioY Haemophilus parasuis SH0165 biotin biosynthesis protein BioY YP_002476001.1 1471674 D 557723 CDS YP_002476002.1 219871627 7277900 complement(1472371..1473180) 1 NC_011852.1 COG:R;COG0561; Cof-like, HAD superfamily hydrolase 1473180 7277900 HAPS_1496 Haemophilus parasuis SH0165 Cof-like, HAD superfamily hydrolase YP_002476002.1 1472371 R 557723 CDS YP_002476003.1 219871628 7277901 1473304..1473981 1 NC_011852.1 COG:R;COG1040; competence protein F 1473981 comF 7277901 comF Haemophilus parasuis SH0165 competence protein F YP_002476003.1 1473304 D 557723 CDS YP_002476004.1 219871629 7277902 complement(1473967..1474767) 1 NC_011852.1 COG:L;COG0084; Mg-dependent deoxyribonuclease 1474767 tatD 7277902 tatD Haemophilus parasuis SH0165 Mg-dependent deoxyribonuclease YP_002476004.1 1473967 R 557723 CDS YP_002476005.1 219871630 7277903 complement(1474780..1477086) 1 NC_011852.1 COG:K;COG0557; ribonuclease R 1477086 vacB 7277903 vacB Haemophilus parasuis SH0165 ribonuclease R YP_002476005.1 1474780 R 557723 CDS YP_002476006.1 219871631 7277904 1477503..1478720 1 NC_011852.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 1478720 dcuB 7277904 dcuB Haemophilus parasuis SH0165 anaerobic C4-dicarboxylate transporter YP_002476006.1 1477503 D 557723 CDS YP_002476007.1 219871632 7277905 1478942..1480276 1 NC_011852.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1480276 dnaA 7277905 dnaA Haemophilus parasuis SH0165 chromosomal replication initiation protein YP_002476007.1 1478942 D 557723 CDS YP_002476008.1 219871633 7277906 1480286..1481389 1 NC_011852.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1481389 dnaN 7277906 dnaN Haemophilus parasuis SH0165 DNA polymerase III subunit beta YP_002476008.1 1480286 D 557723 CDS YP_002476009.1 219871634 7277907 1481421..1481954 1 NC_011852.1 COG:S;COG0762; integral membrane protein 1481954 7277907 HAPS_1503 Haemophilus parasuis SH0165 integral membrane protein YP_002476009.1 1481421 D 557723 CDS YP_002476010.1 219871635 7277908 1481954..1482247 1 NC_011852.1 COG:S;COG1872; hypothetical protein 1482247 7277908 HAPS_1504 Haemophilus parasuis SH0165 hypothetical protein YP_002476010.1 1481954 D 557723 CDS YP_002476011.1 219871636 7277909 1482343..1483122 1 NC_011852.1 COG:R;COG4137; putative ABC-transport permease 1483122 7277909 HAPS_1505 Haemophilus parasuis SH0165 putative ABC-transport permease YP_002476011.1 1482343 D 557723 CDS YP_002476012.1 219871637 7277910 1483304..1484476 1 NC_011852.1 COG:P;COG4536; putative Mg2+ and Co2+ transporter CorB 1484476 corB 7277910 corB Haemophilus parasuis SH0165 putative Mg2+ and Co2+ transporter CorB YP_002476012.1 1483304 D 557723 CDS YP_002476013.1 219871638 7277912 complement(1484885..1486267) 1 NC_011852.1 COG:U;COG0541; signal recognition particle GTPase 1486267 ffh 7277912 ffh Haemophilus parasuis SH0165 signal recognition particle GTPase YP_002476013.1 1484885 R 557723 CDS YP_002476014.1 219871639 7277913 1486633..1487076 1 NC_011852.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1487076 mioC 7277913 mioC Haemophilus parasuis SH0165 flavodoxin YP_002476014.1 1486633 D 557723 CDS YP_002476015.1 219871640 7277914 1487367..1487480 1 NC_011852.1 hypothetical protein 1487480 7277914 HAPS_1510 Haemophilus parasuis SH0165 hypothetical protein YP_002476015.1 1487367 D 557723 CDS YP_002476016.1 219871641 7277916 complement(1494419..1495225) 1 NC_011852.1 catalyzes the O-acetylation of serine; serine acetyltransferase 1495225 cysE 7277916 cysE Haemophilus parasuis SH0165 serine acetyltransferase YP_002476016.1 1494419 R 557723 CDS YP_002476017.1 219871642 7277917 complement(1495228..1496238) 1 NC_011852.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1496238 gpsA 7277917 gpsA Haemophilus parasuis SH0165 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002476017.1 1495228 R 557723 CDS YP_002476018.1 219871643 7277918 complement(1496577..1497293) 1 NC_011852.1 COG:TK;COG0745; two-component response regulator 1497293 arcA 7277918 arcA Haemophilus parasuis SH0165 two-component response regulator YP_002476018.1 1496577 R 557723 CDS YP_002476019.1 219871644 7277919 complement(1497471..1498364) 1 NC_011852.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1498364 cdd 7277919 cdd Haemophilus parasuis SH0165 cytidine deaminase YP_002476019.1 1497471 R 557723 CDS YP_002476020.1 219871645 7277920 complement(1498463..1498810) 1 NC_011852.1 COG:H;COG1539; dihydroneopterin aldolase 1498810 folB 7277920 folB Haemophilus parasuis SH0165 dihydroneopterin aldolase YP_002476020.1 1498463 R 557723 CDS YP_002476021.1 219871646 7277921 1498887..1499498 1 NC_011852.1 COG:S;COG0344; glycerol-3-phosphate acyltransferase PlsY 1499498 plsY 7277921 plsY Haemophilus parasuis SH0165 glycerol-3-phosphate acyltransferase PlsY YP_002476021.1 1498887 D 557723 CDS YP_002476022.1 219871647 7277922 complement(1499582..1500193) 1 NC_011852.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1500193 gidB 7277922 gidB Haemophilus parasuis SH0165 16S rRNA methyltransferase GidB YP_002476022.1 1499582 R 557723 CDS YP_002476023.1 219871648 7277923 complement(1500229..1500666) 1 NC_011852.1 inorganic polyphosphate/ATP-NAD kinase 1500666 ppnK 7277923 ppnK Haemophilus parasuis SH0165 inorganic polyphosphate/ATP-NAD kinase YP_002476023.1 1500229 R 557723 CDS YP_002476024.1 219871649 7277924 complement(1500967..1502778) 1 NC_011852.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1502778 gidA 7277924 gidA Haemophilus parasuis SH0165 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002476024.1 1500967 R 557723 CDS YP_002476025.1 219871650 7277925 1503105..1503242 1 NC_011852.1 hypothetical protein 1503242 7277925 HAPS_1521 Haemophilus parasuis SH0165 hypothetical protein YP_002476025.1 1503105 D 557723 CDS YP_002476026.1 219871651 7277926 1503379..1504125 1 NC_011852.1 COG:KG;COG1349; L-fucose operon activator 1504125 fucR 7277926 fucR Haemophilus parasuis SH0165 L-fucose operon activator YP_002476026.1 1503379 D 557723 CDS YP_002476027.1 219871652 7277927 complement(1504224..1504883) 1 NC_011852.1 COG:S;COG4380; putative lipoprotein 1504883 7277927 HAPS_1523 Haemophilus parasuis SH0165 putative lipoprotein YP_002476027.1 1504224 R 557723 CDS YP_002476028.1 219871653 7277928 complement(1504893..1505240) 1 NC_011852.1 COG:S;COG4259; putative lipoprotein, periplasmic protein 1505240 7277928 HAPS_1524 Haemophilus parasuis SH0165 putative lipoprotein, periplasmic protein YP_002476028.1 1504893 R 557723 CDS YP_002476029.1 219871654 7277929 complement(1505250..1505924) 1 NC_011852.1 COG:M;COG1462; putative lipoprotein, curli production assembly/transport component CsgG 1505924 csgG 7277929 csgG Haemophilus parasuis SH0165 putative lipoprotein, curli production assembly/transport component CsgG YP_002476029.1 1505250 R 557723 CDS YP_002476030.1 219871655 7277930 1506241..1508007 1 NC_011852.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 1508007 fucI 7277930 fucI Haemophilus parasuis SH0165 L-fucose isomerase YP_002476030.1 1506241 D 557723 CDS YP_002476031.1 219871656 7277931 1508148..1509584 1 NC_011852.1 COG:G;COG1070; L-fuculokinase 1509584 fucK 7277931 fucK Haemophilus parasuis SH0165 L-fuculokinase YP_002476031.1 1508148 D 557723 CDS YP_002476032.1 219871657 7277932 1509804..1510244 1 NC_011852.1 COG:G;COG4154; fucose operon FucU protein 1510244 fucU 7277932 fucU Haemophilus parasuis SH0165 fucose operon FucU protein YP_002476032.1 1509804 D 557723 CDS YP_002476033.1 219871658 7277933 1510254..1510907 1 NC_011852.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 1510907 fucA 7277933 fucA Haemophilus parasuis SH0165 L-fuculose phosphate aldolase YP_002476033.1 1510254 D 557723 CDS YP_002476034.1 219871659 7277934 complement(1510956..1511786) 1 NC_011852.1 COG:K;COG1737; RpiR family transcriptional regulator 1511786 rpiR 7277934 rpiR Haemophilus parasuis SH0165 RpiR family transcriptional regulator YP_002476034.1 1510956 R 557723 CDS YP_002476035.1 219871660 7277935 complement(1511908..1513824) 1 NC_011852.1 COG:G;COG0524; myoinositol catabolism protein, sugar kinase 1513824 iolC 7277935 iolC Haemophilus parasuis SH0165 myoinositol catabolism protein, sugar kinase YP_002476035.1 1511908 R 557723 CDS YP_002476036.1 219871661 7277936 1514082..1516016 1 NC_011852.1 COG:E;COG3962; myoinositol catabolism protein, acetolactate synthase 1516016 iolD 7277936 iolD Haemophilus parasuis SH0165 myoinositol catabolism protein, acetolactate synthase YP_002476036.1 1514082 D 557723 CDS YP_002476037.1 219871662 7277937 1516100..1516996 1 NC_011852.1 COG:G;COG1082; myoinositol catabolism protein with xylose isomerase domain (2-keto-myo-inositol dehydratase) 1516996 iolE 7277937 iolE Haemophilus parasuis SH0165 myoinositol catabolism protein with xylose isomerase domain (2-keto-myo-inositol dehydratase) YP_002476037.1 1516100 D 557723 CDS YP_002476038.1 219871663 7277938 1516998..1518008 1 NC_011852.1 COG:R;COG0673; myoinositol 2-dehydrogenase with oxidoreductase domain 1518008 iolG 7277938 iolG Haemophilus parasuis SH0165 myoinositol 2-dehydrogenase with oxidoreductase domain YP_002476038.1 1516998 D 557723 CDS YP_002476039.1 219871664 7277939 complement(1518163..1519509) 1 NC_011852.1 COG:G;COG1455; PTS system cellobiose-specific transporter subunit IIC 1519509 celB 7277939 celB Haemophilus parasuis SH0165 PTS system cellobiose-specific transporter subunit IIC YP_002476039.1 1518163 R 557723 CDS YP_002476040.1 219871665 7277940 complement(1519511..1520848) 1 NC_011852.1 COG:G;COG3669; alpha-L-fucosidase 1520848 alfA 7277940 alfA Haemophilus parasuis SH0165 alpha-L-fucosidase YP_002476040.1 1519511 R 557723 CDS YP_002476041.1 219871666 7277941 complement(1520925..1522058) 1 NC_011852.1 COG:R;COG0673; dehydrogenase 1522058 7277941 HAPS_1537 Haemophilus parasuis SH0165 dehydrogenase YP_002476041.1 1520925 R 557723 CDS YP_002476042.1 219871667 7277942 complement(1522153..1522815) 1 NC_011852.1 COG:G;COG1172; fused D-ribose ABC transporter permease/membrane component 1522815 rbsC 7277942 rbsC Haemophilus parasuis SH0165 fused D-ribose ABC transporter permease/membrane component YP_002476042.1 1522153 R 557723 CDS YP_002476043.1 219871668 7277943 complement(1523151..1524665) 1 NC_011852.1 COG:G;COG1129; fused D-ribose ABC transporter ATP-binding protein 1524665 rbsA 7277943 rbsA Haemophilus parasuis SH0165 fused D-ribose ABC transporter ATP-binding protein YP_002476043.1 1523151 R 557723 CDS YP_002476044.1 219871669 7277944 complement(1524777..1525709) 1 NC_011852.1 COG:G;COG1879; fused D-ribose ABC transporter substrate-binding protein 1525709 rbsD 7277944 rbsD Haemophilus parasuis SH0165 fused D-ribose ABC transporter substrate-binding protein YP_002476044.1 1524777 R 557723 CDS YP_002476045.1 219871670 7277945 complement(1526026..1527537) 1 NC_011852.1 COG:C;COG1012; methylmalonate semialdehyde dehydrogenase 1527537 7277945 HAPS_1541 Haemophilus parasuis SH0165 methylmalonate semialdehyde dehydrogenase YP_002476045.1 1526026 R 557723 CDS YP_002476046.1 219871671 7277946 1527757..1528572 1 NC_011852.1 COG:G;COG3718; myo-inositol catabolism IolB domain-containing protein 1528572 iolB 7277946 iolB Haemophilus parasuis SH0165 myo-inositol catabolism IolB domain-containing protein YP_002476046.1 1527757 D 557723 CDS YP_002476047.1 219871672 7277949 complement(1529203..1529466) 1 NC_011852.1 COG:P;COG2168; protein involved in oxidation of intracellular sulfur 1529466 7277949 HAPS_1545 Haemophilus parasuis SH0165 protein involved in oxidation of intracellular sulfur YP_002476047.1 1529203 R 557723 CDS YP_002476048.1 219871673 7277950 complement(1529476..1529847) 1 NC_011852.1 COG:P;COG2923; putative sulfur oxidation protein DsrF 1529847 dsrF 7277950 dsrF Haemophilus parasuis SH0165 putative sulfur oxidation protein DsrF YP_002476048.1 1529476 R 557723 CDS YP_002476049.1 219871674 7277951 complement(1529849..1530202) 1 NC_011852.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 1530202 tusD 7277951 tusD Haemophilus parasuis SH0165 sulfur transfer complex subunit TusD YP_002476049.1 1529849 R 557723 CDS YP_002476050.1 219871675 7277952 complement(1530202..1530858) 1 NC_011852.1 COG:S;COG2964; YheO domain-containing protein 1530858 yheO 7277952 yheO Haemophilus parasuis SH0165 YheO domain-containing protein YP_002476050.1 1530202 R 557723 CDS YP_002476051.1 219871676 7277953 complement(1530926..1531645) 1 NC_011852.1 COG:O;COG0545; FKBP-type peptidyl-prolyl cis-trans isomerase, macrophage infectivity protein 1531645 fkpA 7277953 fkpA Haemophilus parasuis SH0165 FKBP-type peptidyl-prolyl cis-trans isomerase, macrophage infectivity protein YP_002476051.1 1530926 R 557723 CDS YP_002476052.1 219871677 7277954 1531738..1531962 1 NC_011852.1 COG:S;COG2900; slyX-like protein 1531962 slyX 7277954 slyX Haemophilus parasuis SH0165 slyX-like protein YP_002476052.1 1531738 D 557723 CDS YP_002476053.1 219871678 7277955 1531999..1532664 1 NC_011852.1 COG:OC;COG0526; thiol disulfide oxidoreductase 1532664 7277955 HAPS_1551 Haemophilus parasuis SH0165 thiol disulfide oxidoreductase YP_002476053.1 1531999 D 557723 CDS YP_002476054.1 219871679 7277956 1532661..1533353 1 NC_011852.1 COG:F;COG0775; MTA/SAH nucleosidase 1533353 mtn 7277956 mtn Haemophilus parasuis SH0165 MTA/SAH nucleosidase YP_002476054.1 1532661 D 557723 CDS YP_002476055.1 219871680 7277957 1533518..1534849 1 NC_011852.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 1534849 rimO 7277957 rimO Haemophilus parasuis SH0165 ribosomal protein S12 methylthiotransferase YP_002476055.1 1533518 D 557723 CDS YP_002476056.1 219871681 7277958 1535272..1536177 1 NC_011852.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1536177 glyQ 7277958 glyQ Haemophilus parasuis SH0165 glycyl-tRNA synthetase subunit alpha YP_002476056.1 1535272 D 557723 CDS YP_002476057.1 219871682 7277959 1536231..1536497 1 NC_011852.1 COG:O;COG4545; glutaredoxin-like protein 1536497 7277959 HAPS_1555 Haemophilus parasuis SH0165 glutaredoxin-like protein YP_002476057.1 1536231 D 557723 CDS YP_002476058.1 219871683 7277960 1536579..1537211 1 NC_011852.1 hypothetical protein 1537211 7277960 HAPS_1556 Haemophilus parasuis SH0165 hypothetical protein YP_002476058.1 1536579 D 557723 CDS YP_002476059.1 219871684 7277961 1537371..1537742 1 NC_011852.1 COG:S;COG2852; hypothetical protein 1537742 7277961 HAPS_1557 Haemophilus parasuis SH0165 hypothetical protein YP_002476059.1 1537371 D 557723 CDS YP_002476060.1 219871685 7277962 1537987..1538460 1 NC_011852.1 putative phage associated protein 1538460 7277962 HAPS_1558 Haemophilus parasuis SH0165 putative phage associated protein YP_002476060.1 1537987 D 557723 CDS YP_002476061.1 219871686 7277007 1538492..1540561 1 NC_011852.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1540561 glyS 7277007 glyS Haemophilus parasuis SH0165 glycyl-tRNA synthetase subunit beta YP_002476061.1 1538492 D 557723 CDS YP_002476062.1 219871687 7278371 1540614..1541900 1 NC_011852.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1541900 bioA 7278371 bioA Haemophilus parasuis SH0165 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002476062.1 1540614 D 557723 CDS YP_002476063.1 219871688 7278372 1541893..1543035 1 NC_011852.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1543035 bioF 7278372 bioF Haemophilus parasuis SH0165 8-amino-7-oxononanoate synthase YP_002476063.1 1541893 D 557723 CDS YP_002476064.1 219871689 7278373 1543048..1543713 1 NC_011852.1 COG:S;COG2830; dithiobiotin synthetase 1543713 bioD 7278373 bioD Haemophilus parasuis SH0165 dithiobiotin synthetase YP_002476064.1 1543048 D 557723 CDS YP_002476065.1 219871690 7278374 1543704..1544477 1 NC_011852.1 COG:QR;COG0500; biotin synthesis protein 1544477 bioC 7278374 bioC Haemophilus parasuis SH0165 biotin synthesis protein YP_002476065.1 1543704 D 557723 CDS YP_002476066.1 219871691 7278375 1544467..1545111 1 NC_011852.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1545111 bioD 7278375 bioD Haemophilus parasuis SH0165 dithiobiotin synthetase YP_002476066.1 1544467 D 557723 CDS YP_002476067.1 219871692 7278376 1545134..1545424 1 NC_011852.1 hypothetical protein 1545424 7278376 HAPS_1565 Haemophilus parasuis SH0165 hypothetical protein YP_002476067.1 1545134 D 557723 CDS YP_002476068.1 219871693 7278377 1545548..1546333 1 NC_011852.1 COG:L;COG4973; putative site-specific tyrosine recombinase XerC 1546333 xerC 7278377 xerC Haemophilus parasuis SH0165 putative site-specific tyrosine recombinase XerC YP_002476068.1 1545548 D 557723 CDS YP_002476069.1 219871694 7278378 1546391..1547338 1 NC_011852.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 1547338 rpoH 7278378 rpoH Haemophilus parasuis SH0165 RNA polymerase factor sigma-32 YP_002476069.1 1546391 D 557723 CDS YP_002476070.1 219871695 7278379 complement(1547610..1549853) 1 NC_011852.1 COG:P;COG1629; putative outer membrane colicin Js receptor 1549853 cjrC 7278379 cjrC Haemophilus parasuis SH0165 putative outer membrane colicin Js receptor YP_002476070.1 1547610 R 557723 CDS YP_002476071.1 219871696 7278380 complement(1549869..1550669) 1 NC_011852.1 COG:S;COG3016; putative iron-regulated lipoprotein 1550669 cjrA 7278380 cjrA Haemophilus parasuis SH0165 putative iron-regulated lipoprotein YP_002476071.1 1549869 R 557723 CDS YP_002476072.1 219871697 7278381 complement(1550777..1551565) 1 NC_011852.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 1551565 hmuV 7278381 hmuV Haemophilus parasuis SH0165 hemin importer ATP-binding subunit YP_002476072.1 1550777 R 557723 CDS YP_002476073.1 219871698 7278382 complement(1551565..1552551) 1 NC_011852.1 COG:P;COG0609; hemin transport system permease HmuU 1552551 hmuU 7278382 hmuU Haemophilus parasuis SH0165 hemin transport system permease HmuU YP_002476073.1 1551565 R 557723 CDS YP_002476074.1 219871699 7278383 complement(1552551..1553387) 1 NC_011852.1 COG:P;COG4558; hemin transport system periplasmic protein HmuT 1553387 hmuT 7278383 hmuT Haemophilus parasuis SH0165 hemin transport system periplasmic protein HmuT YP_002476074.1 1552551 R 557723 CDS YP_002476075.1 219871700 7278384 complement(1553440..1554567) 1 NC_011852.1 COG:LU;COG0758; Smf protein, Rossmann fold nucleotide-binding protein involved in DNA uptake 1554567 smf 7278384 smf Haemophilus parasuis SH0165 Smf protein, Rossmann fold nucleotide-binding protein involved in DNA uptake YP_002476075.1 1553440 R 557723 CDS YP_002476076.1 219871701 7278385 1554902..1555414 1 NC_011852.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1555414 def 7278385 def Haemophilus parasuis SH0165 peptide deformylase YP_002476076.1 1554902 D 557723 CDS YP_002476077.1 219871702 7278386 1555426..1556352 1 NC_011852.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 1556352 rfaD 7278386 rfaD Haemophilus parasuis SH0165 ADP-L-glycero-D-manno-heptose-6-epimerase YP_002476077.1 1555426 D 557723 CDS YP_002476078.1 219871703 7278387 1556444..1556587 1 NC_011852.1 hypothetical protein 1556587 7278387 HAPS_1576 Haemophilus parasuis SH0165 hypothetical protein YP_002476078.1 1556444 D 557723 CDS YP_002476079.1 219871704 7278389 complement(1557656..1557814) 1 NC_011852.1 hypothetical protein 1557814 7278389 HAPS_1578 Haemophilus parasuis SH0165 hypothetical protein YP_002476079.1 1557656 R 557723 CDS YP_002476080.1 219871705 7278390 complement(1558035..1558427) 1 NC_011852.1 COG:K;COG1396; XRE family transcriptional regulator 1558427 7278390 HAPS_1579 Haemophilus parasuis SH0165 XRE family transcriptional regulator YP_002476080.1 1558035 R 557723 CDS YP_002476081.1 219871706 7278391 complement(1558455..1558724) 1 NC_011852.1 COG:JD;COG2026; bacteriophage protein/plasmid stabilization system protein 1558724 7278391 HAPS_1580 Haemophilus parasuis SH0165 bacteriophage protein/plasmid stabilization system protein YP_002476081.1 1558455 R 557723 CDS YP_002476082.1 219871707 7278392 complement(1559388..1561574) 1 NC_011852.1 COG:L;COG5519; putative prophage primase 1561574 7278392 HAPS_1581 Haemophilus parasuis SH0165 putative prophage primase YP_002476082.1 1559388 R 557723 CDS YP_002476083.1 219871708 7278394 complement(1561947..1562360) 1 NC_011852.1 phage small subunit terminase 1562360 7278394 HAPS_1583 Haemophilus parasuis SH0165 phage small subunit terminase YP_002476083.1 1561947 R 557723 CDS YP_002476084.1 219871709 7278395 complement(1562348..1562698) 1 NC_011852.1 hypothetical protein 1562698 7278395 HAPS_1584 Haemophilus parasuis SH0165 hypothetical protein YP_002476084.1 1562348 R 557723 CDS YP_002476085.1 219871710 7278396 complement(1562809..1562925) 1 NC_011852.1 hypothetical protein 1562925 7278396 HAPS_1585 Haemophilus parasuis SH0165 hypothetical protein YP_002476085.1 1562809 R 557723 CDS YP_002476086.1 219871711 7278397 complement(1563080..1563406) 1 NC_011852.1 hypothetical protein 1563406 7278397 HAPS_1586 Haemophilus parasuis SH0165 hypothetical protein YP_002476086.1 1563080 R 557723 CDS YP_002476087.1 219871712 7278398 complement(1563990..1565240) 1 NC_011852.1 COG:L;COG0582; phage integrase family site specific recombinase 1565240 7278398 HAPS_1587 Haemophilus parasuis SH0165 phage integrase family site specific recombinase YP_002476087.1 1563990 R 557723 CDS YP_002476088.1 219871713 7278400 1565700..1567085 1 NC_011852.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1567085 selA 7278400 selA Haemophilus parasuis SH0165 selenocysteine synthase YP_002476088.1 1565700 D 557723 CDS YP_002476089.1 219871714 7278401 1567082..1568932 1 NC_011852.1 COG:J;COG3276; selenocysteine-specific elongation factor 1568932 selB 7278401 selB Haemophilus parasuis SH0165 selenocysteine-specific elongation factor YP_002476089.1 1567082 D 557723 CDS YP_002476090.1 219871715 7278402 complement(1569378..1569638) 1 NC_011852.1 COG:K;COG1396; XRE family transcriptional regulator 1569638 7278402 HAPS_1591 Haemophilus parasuis SH0165 XRE family transcriptional regulator YP_002476090.1 1569378 R 557723 CDS YP_002476091.1 219871716 7278403 1570461..1574489 1 NC_011852.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1574489 rpoB 7278403 rpoB Haemophilus parasuis SH0165 DNA-directed RNA polymerase subunit beta YP_002476091.1 1570461 D 557723 CDS YP_002476092.1 219871717 7278404 1574575..1574691 1 NC_011852.1 hypothetical protein 1574691 7278404 HAPS_1593 Haemophilus parasuis SH0165 hypothetical protein YP_002476092.1 1574575 D 557723 CDS YP_002476093.1 219871718 7278405 1574675..1578958 1 NC_011852.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1578958 rpoC 7278405 rpoC Haemophilus parasuis SH0165 DNA-directed RNA polymerase subunit beta' YP_002476093.1 1574675 D 557723 CDS YP_002476094.1 219871719 7278406 complement(1579244..1580329) 1 NC_011852.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 1580329 recF 7278406 recF Haemophilus parasuis SH0165 recombination protein F YP_002476094.1 1579244 R 557723 CDS YP_002476095.1 219871720 7278407 complement(1580372..1580719) 1 NC_011852.1 COG:S;COG3171; hypothetical protein 1580719 7278407 HAPS_1596 Haemophilus parasuis SH0165 hypothetical protein YP_002476095.1 1580372 R 557723 CDS YP_002476096.1 219871721 7278408 complement(1580744..1581493) 1 NC_011852.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1581493 trmB 7278408 trmB Haemophilus parasuis SH0165 tRNA (guanine-N(7)-)-methyltransferase YP_002476096.1 1580744 R 557723 CDS YP_002476097.1 219871722 7278409 complement(1581509..1582426) 1 NC_011852.1 COG:I;COG0332; 3-oxoacyl-ACP synthase 1582426 fabH 7278409 fabH Haemophilus parasuis SH0165 3-oxoacyl-ACP synthase YP_002476097.1 1581509 R 557723 CDS YP_002476098.1 219871723 7278410 complement(1582550..1583521) 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 1583521 7278410 HAPS_1599 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002476098.1 1582550 R 557723 CDS YP_002476099.1 219871724 7278411 1584072..1585043 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 1585043 7278411 HAPS_1600 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002476099.1 1584072 D 557723 CDS YP_002476100.1 219871725 7278412 complement(1585159..1586337) 1 NC_011852.1 carbamoylphosphate synthase large subunit 1586337 pyrAB 7278412 pyrAB Haemophilus parasuis SH0165 carbamoylphosphate synthase large subunit YP_002476100.1 1585159 R 557723 CDS YP_002476101.1 219871726 7278413 complement(1586519..1587913) 1 NC_011852.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1587913 fumC 7278413 fumC Haemophilus parasuis SH0165 fumarate hydratase YP_002476101.1 1586519 R 557723 CDS YP_002476102.1 219871727 7278414 complement(1588060..1588698) 1 NC_011852.1 DNA transformation protein, regulator of competence-specific genes 1588698 tfoX 7278414 tfoX Haemophilus parasuis SH0165 DNA transformation protein, regulator of competence-specific genes YP_002476102.1 1588060 R 557723 CDS YP_002476103.1 219871728 7278415 complement(1588846..1588980) 1 NC_011852.1 hypothetical protein 1588980 7278415 HAPS_1604 Haemophilus parasuis SH0165 hypothetical protein YP_002476103.1 1588846 R 557723 CDS YP_002476104.1 219871729 7278416 1589157..1589468 1 NC_011852.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1589468 rpsJ 7278416 rpsJ Haemophilus parasuis SH0165 30S ribosomal protein S10 YP_002476104.1 1589157 D 557723 CDS YP_002476105.1 219871730 7278417 1589485..1590111 1 NC_011852.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1590111 rplC 7278417 rplC Haemophilus parasuis SH0165 50S ribosomal protein L3 YP_002476105.1 1589485 D 557723 CDS YP_002476106.1 219871731 7278418 1590127..1590729 1 NC_011852.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1590729 rplD 7278418 rplD Haemophilus parasuis SH0165 50S ribosomal protein L4 YP_002476106.1 1590127 D 557723 CDS YP_002476107.1 219871732 7278419 1590726..1591031 1 NC_011852.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1591031 rplW 7278419 rplW Haemophilus parasuis SH0165 50S ribosomal protein L23 YP_002476107.1 1590726 D 557723 CDS YP_002476108.1 219871733 7278420 1591052..1591873 1 NC_011852.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1591873 rplB 7278420 rplB Haemophilus parasuis SH0165 50S ribosomal protein L2 YP_002476108.1 1591052 D 557723 CDS YP_002476109.1 219871734 7278421 1591902..1592177 1 NC_011852.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1592177 rpsS 7278421 rpsS Haemophilus parasuis SH0165 30S ribosomal protein S19 YP_002476109.1 1591902 D 557723 CDS YP_002476110.1 219871735 7278422 1592188..1592520 1 NC_011852.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1592520 rplV 7278422 rplV Haemophilus parasuis SH0165 50S ribosomal protein L22 YP_002476110.1 1592188 D 557723 CDS YP_002476111.1 219871736 7278423 1592538..1593242 1 NC_011852.1 COG:J;COG0092; 30S ribosomal protein S3 1593242 rpsC 7278423 rpsC Haemophilus parasuis SH0165 30S ribosomal protein S3 YP_002476111.1 1592538 D 557723 CDS YP_002476112.1 219871737 7278424 1593255..1593665 1 NC_011852.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1593665 rplP 7278424 rplP Haemophilus parasuis SH0165 50S ribosomal protein L16 YP_002476112.1 1593255 D 557723 CDS YP_002476113.1 219871738 7278425 1593665..1593856 1 NC_011852.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1593856 rpmC 7278425 rpmC Haemophilus parasuis SH0165 50S ribosomal protein L29 YP_002476113.1 1593665 D 557723 CDS YP_002476114.1 219871739 7278426 1593856..1594110 1 NC_011852.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1594110 rpsQ 7278426 rpsQ Haemophilus parasuis SH0165 30S ribosomal protein S17 YP_002476114.1 1593856 D 557723 CDS YP_002476115.1 219871740 7278427 1594826..1596832 1 NC_011852.1 COG:G;COG4409; neuraminidase/exo-alpha-sialidase nanH 1596832 nanH 7278427 nanH Haemophilus parasuis SH0165 neuraminidase/exo-alpha-sialidase nanH YP_002476115.1 1594826 D 557723 CDS YP_002476116.1 219871741 7278429 complement(1597394..1599190) 1 NC_011852.1 COG:P;COG0471; di- and tricarboxylate transporter/DASS family divalent anion:sodium (Na+) symporter 1599190 7278429 HAPS_1618 Haemophilus parasuis SH0165 di- and tricarboxylate transporter/DASS family divalent anion:sodium (Na+) symporter YP_002476116.1 1597394 R 557723 CDS YP_002476117.1 219871742 7278430 1599680..1600066 1 NC_011852.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 1600066 atpI 7278430 atpI Haemophilus parasuis SH0165 F0F1 ATP synthase subunit I YP_002476117.1 1599680 D 557723 CDS YP_002476118.1 219871743 7278431 1600095..1600886 1 NC_011852.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1600886 atpB 7278431 atpB Haemophilus parasuis SH0165 F0F1 ATP synthase subunit A YP_002476118.1 1600095 D 557723 CDS YP_002476119.1 219871744 7278432 1601027..1601281 1 NC_011852.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1601281 atpE 7278432 atpE Haemophilus parasuis SH0165 F0F1 ATP synthase subunit C YP_002476119.1 1601027 D 557723 CDS YP_002476120.1 219871745 7278433 1601343..1601813 1 NC_011852.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1601813 atpF 7278433 atpF Haemophilus parasuis SH0165 F0F1 ATP synthase subunit B YP_002476120.1 1601343 D 557723 CDS YP_002476121.1 219871746 7278434 1601827..1602360 1 NC_011852.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1602360 atpH 7278434 atpH Haemophilus parasuis SH0165 F0F1 ATP synthase subunit delta YP_002476121.1 1601827 D 557723 CDS YP_002476122.1 219871747 7278435 1602373..1603914 1 NC_011852.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1603914 atpA 7278435 atpA Haemophilus parasuis SH0165 F0F1 ATP synthase subunit alpha YP_002476122.1 1602373 D 557723 CDS YP_002476123.1 219871748 7278436 1603937..1604803 1 NC_011852.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1604803 atpG 7278436 atpG Haemophilus parasuis SH0165 F0F1 ATP synthase subunit gamma YP_002476123.1 1603937 D 557723 CDS YP_002476124.1 219871749 7278437 1604824..1606197 1 NC_011852.1 COG:C;COG0055; F0F1 ATP synthase subunit beta/H(+)-transporting two-sector ATPase, F(1) subunit beta 1606197 atpD 7278437 atpD Haemophilus parasuis SH0165 F0F1 ATP synthase subunit beta/H(+)-transporting two-sector ATPase, F(1) subunit beta YP_002476124.1 1604824 D 557723 CDS YP_002476125.1 219871750 7278438 1606224..1606640 1 NC_011852.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1606640 atpC 7278438 atpC Haemophilus parasuis SH0165 F0F1 ATP synthase subunit epsilon YP_002476125.1 1606224 D 557723 CDS YP_002476126.1 219871751 7278439 1606715..1607704 1 NC_011852.1 COG:K;COG1609; ribose operon repressor 1607704 rbsR 7278439 rbsR Haemophilus parasuis SH0165 ribose operon repressor YP_002476126.1 1606715 D 557723 CDS YP_002476127.1 219871752 7278440 1607819..1608238 1 NC_011852.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 1608238 rbsD 7278440 rbsD Haemophilus parasuis SH0165 D-ribose pyranase YP_002476127.1 1607819 D 557723 CDS YP_002476128.1 219871753 7278441 1608248..1609747 1 NC_011852.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 1609747 rbsA 7278441 rbsA Haemophilus parasuis SH0165 D-ribose transporter ATP-binding protein YP_002476128.1 1608248 D 557723 CDS YP_002476129.1 219871754 7278442 1609759..1610718 1 NC_011852.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 1610718 rbsC 7278442 rbsC Haemophilus parasuis SH0165 ribose ABC transporter permease YP_002476129.1 1609759 D 557723 CDS YP_002476130.1 219871755 7278443 1610759..1611631 1 NC_011852.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 1611631 rbsB 7278443 rbsB Haemophilus parasuis SH0165 D-ribose transporter subunit RbsB YP_002476130.1 1610759 D 557723 CDS YP_002476131.1 219871756 7278444 1611704..1612627 1 NC_011852.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 1612627 rbsK 7278444 rbsK Haemophilus parasuis SH0165 ribokinase YP_002476131.1 1611704 D 557723 CDS YP_002476132.1 219871757 7278445 1613112..1614374 1 NC_011852.1 COG:E;COG0174; glutamine synthetase 1614374 glnA 7278445 glnA Haemophilus parasuis SH0165 glutamine synthetase YP_002476132.1 1613112 D 557723 CDS YP_002476133.1 219871758 7278447 1615430..1615624 1 NC_011852.1 hypothetical protein 1615624 7278447 HAPS_1636 Haemophilus parasuis SH0165 hypothetical protein YP_002476133.1 1615430 D 557723 CDS YP_002476134.1 219871759 7278448 complement(1615601..1616251) 1 NC_011852.1 COG:R;COG0300; short-chain dehydrogenase/reductase SDR 1616251 dltE 7278448 dltE Haemophilus parasuis SH0165 short-chain dehydrogenase/reductase SDR YP_002476134.1 1615601 R 557723 CDS YP_002476135.1 219871760 7278449 1616337..1617197 1 NC_011852.1 AraC family transcriptional regulator 1617197 7278449 HAPS_1638 Haemophilus parasuis SH0165 AraC family transcriptional regulator YP_002476135.1 1616337 D 557723 CDS YP_002476136.1 219871761 7278451 complement(1617521..1617964) 1 NC_011852.1 COG:S;COG4922; pyruvate kinase 1617964 pykF 7278451 pykF Haemophilus parasuis SH0165 pyruvate kinase YP_002476136.1 1617521 R 557723 CDS YP_002476137.1 219871762 7277554 1618099..1618989 1 NC_011852.1 COG:K;COG0583; LysR family transcriptional regulator 1618989 7277554 HAPS_1641 Haemophilus parasuis SH0165 LysR family transcriptional regulator YP_002476137.1 1618099 D 557723 CDS YP_002476138.1 219871763 7277557 1620027..1623614 1 NC_011852.1 COG:L;COG1074; exodeoxyribonuclease V subunit beta 1623614 recB 7277557 recB Haemophilus parasuis SH0165 exodeoxyribonuclease V subunit beta YP_002476138.1 1620027 D 557723 CDS YP_002476139.1 219871764 7277559 complement(1624601..1626373) 1 NC_011852.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1626373 aspS 7277559 aspS Haemophilus parasuis SH0165 aspartyl-tRNA synthetase YP_002476139.1 1624601 R 557723 CDS YP_002476140.1 219871765 7277560 1626553..1627152 1 NC_011852.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1627152 grpE 7277560 grpE Haemophilus parasuis SH0165 heat shock protein GrpE YP_002476140.1 1626553 D 557723 CDS YP_002476141.1 219871766 7277561 1627249..1627551 1 NC_011852.1 hypothetical protein 1627551 7277561 HAPS_1648 Haemophilus parasuis SH0165 hypothetical protein YP_002476141.1 1627249 D 557723 CDS YP_002476142.1 219871767 7277562 1627615..1628067 1 NC_011852.1 COG:S;COG2707; hypothetical protein 1628067 7277562 HAPS_1649 Haemophilus parasuis SH0165 hypothetical protein YP_002476142.1 1627615 D 557723 CDS YP_002476143.1 219871768 7277563 1628082..1632020 1 NC_011852.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1632020 hrpA 7277563 hrpA Haemophilus parasuis SH0165 ATP-dependent RNA helicase HrpA YP_002476143.1 1628082 D 557723 CDS YP_002476144.1 219871769 7277564 1632228..1633418 1 NC_011852.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1633418 tyrS 7277564 tyrS Haemophilus parasuis SH0165 tyrosyl-tRNA synthetase YP_002476144.1 1632228 D 557723 CDS YP_002476145.1 219871770 7277565 complement(1633508..1634644) 1 NC_011852.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1634644 alr 7277565 alr Haemophilus parasuis SH0165 alanine racemase YP_002476145.1 1633508 R 557723 CDS YP_002476146.1 219871771 7277566 1634768..1635682 1 NC_011852.1 COG:O;COG0330; SPFH domain-containing protein 1635682 hflC 7277566 hflC Haemophilus parasuis SH0165 SPFH domain-containing protein YP_002476146.1 1634768 D 557723 CDS YP_002476147.1 219871772 7277567 1635692..1636132 1 NC_011852.1 COG:OU;COG1585; regulator of membrane protease activity 1636132 7277567 HAPS_1654 Haemophilus parasuis SH0165 regulator of membrane protease activity YP_002476147.1 1635692 D 557723 CDS YP_002476148.1 219871773 7277568 complement(1636207..1637433) 1 NC_011852.1 COG:F;COG2233; uracil permease 1637433 uraA 7277568 uraA Haemophilus parasuis SH0165 uracil permease YP_002476148.1 1636207 R 557723 CDS YP_002476149.1 219871774 7277569 complement(1637628..1638923) 1 NC_011852.1 COG:R;COG2252; xanthine/uracil/vitamin C permease 1638923 7277569 HAPS_1656 Haemophilus parasuis SH0165 xanthine/uracil/vitamin C permease YP_002476149.1 1637628 R 557723 CDS YP_002476150.1 219871775 7277572 complement(1639662..1640411) 1 NC_011852.1 COG:R;COG4221; NADP-dependent dehydrogenase 1640411 7277572 HAPS_1659 Haemophilus parasuis SH0165 NADP-dependent dehydrogenase YP_002476150.1 1639662 R 557723 CDS YP_002476151.1 219871776 7277573 complement(1640467..1641129) 1 NC_011852.1 COG:P;COG0288; carbonic anhydrase 1641129 7277573 HAPS_1660 Haemophilus parasuis SH0165 carbonic anhydrase YP_002476151.1 1640467 R 557723 CDS YP_002476152.1 219871777 7277574 1641487..1642458 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 1642458 7277574 HAPS_1661 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002476152.1 1641487 D 557723 CDS YP_002476153.1 219871778 7277575 1642648..1643334 1 NC_011852.1 COG:V;COG1136; lipoprotein-releasing system ATP-binding protein lolD 1643334 lolD 7277575 lolD Haemophilus parasuis SH0165 lipoprotein-releasing system ATP-binding protein lolD YP_002476153.1 1642648 D 557723 CDS YP_002476154.1 219871779 7277576 1643334..1644584 1 NC_011852.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1644584 lolE 7277576 lolE Haemophilus parasuis SH0165 outer membrane-specific lipoprotein transporter subunit LolE YP_002476154.1 1643334 D 557723 CDS YP_002476155.1 219871780 7277577 complement(1644618..1645604) 1 NC_011852.1 COG:FR;COG0402; hypothetical protein 1645604 codA 7277577 codA Haemophilus parasuis SH0165 hypothetical protein YP_002476155.1 1644618 R 557723 CDS YP_002476156.1 219871781 7277578 complement(1645846..1646619) 1 NC_011852.1 COG:H;COG1179; molybdopterin/thiamine biosynthesis dinucleotide-utilizing protein 1646619 7277578 HAPS_1665 Haemophilus parasuis SH0165 molybdopterin/thiamine biosynthesis dinucleotide-utilizing protein YP_002476156.1 1645846 R 557723 CDS YP_002476157.1 219871782 7277579 complement(1646665..1647948) 1 NC_011852.1 COG:C;COG1252; NADH dehydrogenase 1647948 ndh 7277579 ndh Haemophilus parasuis SH0165 NADH dehydrogenase YP_002476157.1 1646665 R 557723 CDS YP_002476158.1 219871783 7277580 complement(1648287..1648937) 1 NC_011852.1 COG:QR;COG0500; ubiquinone/menaquinone biosynthesis methyltransferase 1648937 ubiE 7277580 ubiE Haemophilus parasuis SH0165 ubiquinone/menaquinone biosynthesis methyltransferase YP_002476158.1 1648287 R 557723 CDS YP_002476159.1 219871784 7277581 complement(1649057..1650007) 1 NC_011852.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1650007 lpxM 7277581 lpxM Haemophilus parasuis SH0165 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002476159.1 1649057 R 557723 CDS YP_002476160.1 219871785 7277582 complement(1650017..1650706) 1 NC_011852.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1650706 rnfE 7277582 rnfE Haemophilus parasuis SH0165 electron transport complex protein RsxE YP_002476160.1 1650017 R 557723 CDS YP_002476161.1 219871786 7277583 complement(1650896..1651438) 1 NC_011852.1 COG:L;COG1943; hypothetical protein 1651438 7277583 HAPS_1670 Haemophilus parasuis SH0165 hypothetical protein YP_002476161.1 1650896 R 557723 CDS YP_002476162.1 219871787 7277584 complement(1651472..1652110) 1 NC_011852.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1652110 rnfG 7277584 rnfG Haemophilus parasuis SH0165 electron transport complex protein RnfG YP_002476162.1 1651472 R 557723 CDS YP_002476163.1 219871788 7277585 complement(1652107..1653174) 1 NC_011852.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1653174 rnfD 7277585 rnfD Haemophilus parasuis SH0165 electron transport complex protein RnfD YP_002476163.1 1652107 R 557723 CDS YP_002476164.1 219871789 7277586 complement(1653205..1653837) 1 NC_011852.1 COG:S;COG2860; membrane protein, yadS protein 1653837 yadS 7277586 yadS Haemophilus parasuis SH0165 membrane protein, yadS protein YP_002476164.1 1653205 R 557723 CDS YP_002476165.1 219871790 7277587 complement(1653916..1655916) 1 NC_011852.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1655916 rnfC 7277587 rnfC Haemophilus parasuis SH0165 electron transport complex protein RnfC YP_002476165.1 1653916 R 557723 CDS YP_002476166.1 219871791 7277588 complement(1655906..1656514) 1 NC_011852.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1656514 rnfB 7277588 rnfB Haemophilus parasuis SH0165 electron transport complex protein RnfB YP_002476166.1 1655906 R 557723 CDS YP_002476167.1 219871792 7277589 complement(1656514..1657095) 1 NC_011852.1 COG:C;COG4657; Na(+)-translocating NADH-quinone reductase subunit E 1657095 rnfA 7277589 rnfA Haemophilus parasuis SH0165 Na(+)-translocating NADH-quinone reductase subunit E YP_002476167.1 1656514 R 557723 CDS YP_002476168.1 219871793 7277590 1657131..1657283 1 NC_011852.1 hypothetical protein 1657283 7277590 HAPS_1677 Haemophilus parasuis SH0165 hypothetical protein YP_002476168.1 1657131 D 557723 CDS YP_002476169.1 219871794 7277592 1657751..1658578 1 NC_011852.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1658578 pdxY 7277592 pdxY Haemophilus parasuis SH0165 pyridoxamine kinase YP_002476169.1 1657751 D 557723 CDS YP_002476170.1 219871795 7277594 complement(1659414..1660400) 1 NC_011852.1 COG:L;COG3547; ISCro4, family IS3 1660400 7277594 HAPS_1681 Haemophilus parasuis SH0165 ISCro4, family IS3 YP_002476170.1 1659414 R 557723 CDS YP_002476171.1 219871796 7277595 1660663..1660986 1 NC_011852.1 COG:L;COG2963; IS222, family IS3 1660986 7277595 HAPS_1682 Haemophilus parasuis SH0165 IS222, family IS3 YP_002476171.1 1660663 D 557723 CDS YP_002476172.1 219871797 7277599 complement(1666316..1668031) 1 NC_011852.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1668031 proS 7277599 proS Haemophilus parasuis SH0165 prolyl-tRNA synthetase YP_002476172.1 1666316 R 557723 CDS YP_002476173.1 219871798 7277600 1668384..1668614 1 NC_011852.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1668614 acpP 7277600 acpP Haemophilus parasuis SH0165 acyl carrier protein YP_002476173.1 1668384 D 557723 CDS YP_002476174.1 219871799 7277601 1668761..1669684 1 NC_011852.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 1669684 rbsK 7277601 rbsK Haemophilus parasuis SH0165 aminoimidazole riboside kinase YP_002476174.1 1668761 D 557723 CDS YP_002476175.1 219871800 7277602 complement(1669846..1670577) 1 NC_011852.1 COG:P;COG3142; copper homeostasis protein 1670577 cutC 7277602 cutC Haemophilus parasuis SH0165 copper homeostasis protein YP_002476175.1 1669846 R 557723 CDS YP_002476176.1 219871801 7277603 complement(1670578..1671567) 1 NC_011852.1 COG:G;COG2017; aldose 1-epimerase 1671567 galM 7277603 galM Haemophilus parasuis SH0165 aldose 1-epimerase YP_002476176.1 1670578 R 557723 CDS YP_002476177.1 219871802 7277604 complement(1671638..1672792) 1 NC_011852.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1672792 galK 7277604 galK Haemophilus parasuis SH0165 galactokinase YP_002476177.1 1671638 R 557723 CDS YP_002476178.1 219871803 7277607 complement(1673636..1674073) 1 NC_011852.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 1674073 holC 7277607 holC Haemophilus parasuis SH0165 DNA polymerase III subunit chi YP_002476178.1 1673636 R 557723 CDS YP_002476179.1 219871804 7277608 complement(1674179..1675966) 1 NC_011852.1 COG:I;COG1022; long chain fatty acid CoA ligase 1675966 7277608 HAPS_1695 Haemophilus parasuis SH0165 long chain fatty acid CoA ligase YP_002476179.1 1674179 R 557723 CDS YP_002476180.1 219871805 7277615 complement(1680275..1680835) 1 NC_011852.1 COG:R;COG3381; putative anaerobic dehydrogenase TorD 1680835 torD 7277615 torD Haemophilus parasuis SH0165 putative anaerobic dehydrogenase TorD YP_002476180.1 1680275 R 557723 CDS YP_002476181.1 219871806 7277616 1680895..1681740 1 NC_011852.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 1681740 nfo 7277616 nfo Haemophilus parasuis SH0165 endonuclease IV YP_002476181.1 1680895 D 557723 CDS YP_002476182.1 219871807 7277618 1682681..1683109 1 NC_011852.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1683109 rplK 7277618 rplK Haemophilus parasuis SH0165 50S ribosomal protein L11 YP_002476182.1 1682681 D 557723 CDS YP_002476183.1 219871808 7277619 1683114..1683803 1 NC_011852.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1683803 rplA 7277619 rplA Haemophilus parasuis SH0165 50S ribosomal protein L1 YP_002476183.1 1683114 D 557723 CDS YP_002476184.1 219871809 7277621 1684900..1685316 1 NC_011852.1 COG:S;COG2259; DoxX family protein membrane protein 1685316 7277621 HAPS_1708 Haemophilus parasuis SH0165 DoxX family protein membrane protein YP_002476184.1 1684900 D 557723 CDS YP_002476185.1 219871810 7277625 1686960..1687373 1 NC_011852.1 hypothetical protein 1687373 7277625 HAPS_1712 Haemophilus parasuis SH0165 hypothetical protein YP_002476185.1 1686960 D 557723 CDS YP_002476186.1 219871811 7277626 complement(1687811..1689424) 1 NC_011852.1 COG:V;COG0286; type I restriction-modification system, M subunit 1689424 hsdM 7277626 hsdM Haemophilus parasuis SH0165 type I restriction-modification system, M subunit YP_002476186.1 1687811 R 557723 CDS YP_002476187.1 219871812 7277630 complement(1692019..1692786) 1 NC_011852.1 Lj965 prophage protein 1692786 7277630 HAPS_1717 Haemophilus parasuis SH0165 Lj965 prophage protein YP_002476187.1 1692019 R 557723 CDS YP_002476188.1 219871813 7277631 complement(1692783..1693220) 1 NC_011852.1 putative Lj965 prophage protein 1693220 7277631 HAPS_1718 Haemophilus parasuis SH0165 putative Lj965 prophage protein YP_002476188.1 1692783 R 557723 CDS YP_002476189.1 219871814 7277632 complement(1693241..1696201) 1 NC_011852.1 COG:V;COG0610; HsdR family type I site-specific deoxyribonuclease 1696201 hsdR 7277632 hsdR Haemophilus parasuis SH0165 HsdR family type I site-specific deoxyribonuclease YP_002476189.1 1693241 R 557723 CDS YP_002476190.1 219871815 7277633 1696548..1696853 1 NC_011852.1 hypothetical protein 1696853 7277633 HAPS_1720 Haemophilus parasuis SH0165 hypothetical protein YP_002476190.1 1696548 D 557723 CDS YP_002476191.1 219871816 7277634 complement(1697407..1697772) 1 NC_011852.1 COG:K;COG1733; HxlR family transcriptional regulator 1697772 7277634 HAPS_1721 Haemophilus parasuis SH0165 HxlR family transcriptional regulator YP_002476191.1 1697407 R 557723 CDS YP_002476192.1 219871817 7277635 1697917..1698168 1 NC_011852.1 hypothetical protein 1698168 7277635 HAPS_1722 Haemophilus parasuis SH0165 hypothetical protein YP_002476192.1 1697917 D 557723 CDS YP_002476193.1 219871818 7277638 complement(1699846..1700793) 1 NC_011852.1 COG:G;COG1879; D-ribose ABC transporter substrate-binding component RbsB 1700793 rbsB 7277638 rbsB Haemophilus parasuis SH0165 D-ribose ABC transporter substrate-binding component RbsB YP_002476193.1 1699846 R 557723 CDS YP_002476194.1 219871819 7277639 complement(1700814..1701812) 1 NC_011852.1 COG:G;COG1172; D-ribose ABC transporter permease protein RbsC 1701812 rbsC 7277639 rbsC Haemophilus parasuis SH0165 D-ribose ABC transporter permease protein RbsC YP_002476194.1 1700814 R 557723 CDS YP_002476195.1 219871820 7277640 complement(1701824..1703359) 1 NC_011852.1 COG:G;COG1129; D-ribose ABC transporter ATP binding protein RbsA 1703359 rbsA 7277640 rbsA Haemophilus parasuis SH0165 D-ribose ABC transporter ATP binding protein RbsA YP_002476195.1 1701824 R 557723 CDS YP_002476196.1 219871821 7277641 complement(1703590..1704801) 1 NC_011852.1 COG:G;COG1482; mannose-6-phosphate isomerase 1704801 manA 7277641 manA Haemophilus parasuis SH0165 mannose-6-phosphate isomerase YP_002476196.1 1703590 R 557723 CDS YP_002476197.1 219871822 7277642 complement(1704798..1705256) 1 NC_011852.1 COG:S;COG4811; hypothetical protein 1705256 7277642 HAPS_1729 Haemophilus parasuis SH0165 hypothetical protein YP_002476197.1 1704798 R 557723 CDS YP_002476198.1 219871823 7277643 complement(1705330..1706166) 1 NC_011852.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1706166 manZ 7277643 manZ Haemophilus parasuis SH0165 PTS system mannose-specific transporter subunit IID YP_002476198.1 1705330 R 557723 CDS YP_002476199.1 219871824 7277644 complement(1706179..1706979) 1 NC_011852.1 COG:G;COG3715; PTS system mannose/fructose/sorbose family transporter subunit IIC 1706979 manY 7277644 manY Haemophilus parasuis SH0165 PTS system mannose/fructose/sorbose family transporter subunit IIC YP_002476199.1 1706179 R 557723 CDS YP_002476200.1 219871825 7277645 complement(1706990..1707970) 1 NC_011852.1 COG:G;COG3444; PTS system mannose-specific EIIAB component 1707970 manX 7277645 manX Haemophilus parasuis SH0165 PTS system mannose-specific EIIAB component YP_002476200.1 1706990 R 557723 CDS YP_002476201.1 219871826 7277646 complement(1708294..1709259) 1 NC_011852.1 COG:H;COG0276; protoheme ferro-lyase 1709259 hemH 7277646 hemH Haemophilus parasuis SH0165 protoheme ferro-lyase YP_002476201.1 1708294 R 557723 CDS YP_002476202.1 219871827 7277647 complement(1709476..1712733) 1 NC_011852.1 COG:L;COG1330; exodeoxyribonuclease V subunit gamma 1712733 recC 7277647 recC Haemophilus parasuis SH0165 exodeoxyribonuclease V subunit gamma YP_002476202.1 1709476 R 557723 CDS YP_002476203.1 219871828 7277648 complement(1712835..1714007) 1 NC_011852.1 COG:HC;COG0654; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 1714007 ubiF 7277648 ubiF Haemophilus parasuis SH0165 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_002476203.1 1712835 R 557723 CDS YP_002476204.1 219871829 7277649 complement(1714010..1714132) 1 NC_011852.1 hypothetical protein 1714132 7277649 HAPS_1736 Haemophilus parasuis SH0165 hypothetical protein YP_002476204.1 1714010 R 557723 CDS YP_002476205.1 219871830 7277650 1714220..1714525 1 NC_011852.1 COG:S;COG3657; addiction module killer protein 1714525 hicA 7277650 hicA Haemophilus parasuis SH0165 addiction module killer protein YP_002476205.1 1714220 D 557723 CDS YP_002476206.1 219871831 7277651 1714532..1714837 1 NC_011852.1 COG:K;COG3636; putative transcriptional regulator 1714837 7277651 HAPS_1738 Haemophilus parasuis SH0165 putative transcriptional regulator YP_002476206.1 1714532 D 557723 CDS YP_002476207.1 219871832 7277652 1715044..1715403 1 NC_011852.1 COG:S;COG4226; HicB-like protein 1715403 hicB 7277652 hicB Haemophilus parasuis SH0165 HicB-like protein YP_002476207.1 1715044 D 557723 CDS YP_002476208.1 219871833 7277653 1715495..1717027 1 NC_011852.1 COG:O;COG0606; competence protein M 1717027 comM 7277653 comM Haemophilus parasuis SH0165 competence protein M YP_002476208.1 1715495 D 557723 CDS YP_002476209.1 219871834 7277654 complement(1717024..1718013) 1 NC_011852.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1718013 holB 7277654 holB Haemophilus parasuis SH0165 DNA polymerase III subunit delta' YP_002476209.1 1717024 R 557723 CDS YP_002476210.1 219871835 7277655 complement(1718384..1719010) 1 NC_011852.1 COG:F;COG0125; thymidylate kinase 1719010 tdk 7277655 tdk Haemophilus parasuis SH0165 thymidylate kinase YP_002476210.1 1718384 R 557723 CDS YP_002476211.1 219871836 7277656 complement(1719010..1720044) 1 NC_011852.1 COG:R;COG1559; periplasmic solute-binding protein 1720044 fbp 7277656 fbp Haemophilus parasuis SH0165 periplasmic solute-binding protein YP_002476211.1 1719010 R 557723 CDS YP_002476212.1 219871837 7277660 complement(1720591..1721382) 1 NC_011852.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1721382 tpiA 7277660 tpiA Haemophilus parasuis SH0165 triosephosphate isomerase YP_002476212.1 1720591 R 557723 CDS YP_002476213.1 219871838 7277662 1721810..1722574 1 NC_011852.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 1722574 surE 7277662 surE Haemophilus parasuis SH0165 stationary phase survival protein SurE YP_002476213.1 1721810 D 557723 CDS YP_002476214.1 219871839 7277663 1722575..1723159 1 NC_011852.1 COG:S;COG1238; membrane lipoprotein B 1723159 apoB 7277663 apoB Haemophilus parasuis SH0165 membrane lipoprotein B YP_002476214.1 1722575 D 557723 CDS YP_002476215.1 219871840 7277664 1723169..1723678 1 NC_011852.1 lipoprotein 1723678 7277664 HAPS_1751 Haemophilus parasuis SH0165 lipoprotein YP_002476215.1 1723169 D 557723 CDS YP_002476216.1 219871841 7277665 1723806..1724981 1 NC_011852.1 COG:M;COG0739; outer membrane antigenic lipoprotein B 1724981 lppB 7277665 lppB Haemophilus parasuis SH0165 outer membrane antigenic lipoprotein B YP_002476216.1 1723806 D 557723 CDS YP_002476217.1 219871842 7277667 complement(1728952..1729452) 1 NC_011852.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 1729452 rraA 7277667 rraA Haemophilus parasuis SH0165 ribonuclease activity regulator protein RraA YP_002476217.1 1728952 R 557723 CDS YP_002476218.1 219871843 7277668 complement(1729516..1730766) 1 NC_011852.1 COG:S;COG2995; paraquat-inducible protein A, PqiA 1730766 pqiA 7277668 pqiA Haemophilus parasuis SH0165 paraquat-inducible protein A, PqiA YP_002476218.1 1729516 R 557723 CDS YP_002476219.1 219871844 7277669 complement(1730763..1731350) 1 NC_011852.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1731350 rnhB 7277669 rnhB Haemophilus parasuis SH0165 ribonuclease HII YP_002476219.1 1730763 R 557723 CDS YP_002476220.1 219871845 7277670 complement(1731354..1732244) 1 NC_011852.1 COG:R;COG0354; putative GCV family glycine cleavage complex aminomethyltransferase 1732244 7277670 HAPS_1757 Haemophilus parasuis SH0165 putative GCV family glycine cleavage complex aminomethyltransferase YP_002476220.1 1731354 R 557723 CDS YP_002476221.1 219871846 7277672 complement(1732586..1732978) 1 NC_011852.1 COG:K;COG1846; MarR family transcriptional regulator 1732978 7277672 HAPS_1759 Haemophilus parasuis SH0165 MarR family transcriptional regulator YP_002476221.1 1732586 R 557723 CDS YP_002476222.1 219871847 7277674 1733606..1735519 1 NC_011852.1 restriction enzyme subunit alpha/N-6 DNA methylase 1735519 bcgIA 7277674 bcgIA Haemophilus parasuis SH0165 restriction enzyme subunit alpha/N-6 DNA methylase YP_002476222.1 1733606 D 557723 CDS YP_002476223.1 219871848 7277675 1735512..1736648 1 NC_011852.1 restriction enzyme subunit beta/N-6 DNA methylase 1736648 bcgIB 7277675 bcgIB Haemophilus parasuis SH0165 restriction enzyme subunit beta/N-6 DNA methylase YP_002476223.1 1735512 D 557723 CDS YP_002476224.1 219871849 7277677 1737241..1738245 1 NC_011852.1 COG:R;COG3943; glutamate-1-semialdehyde 2,1-aminomutase 1738245 hemL 7277677 hemL Haemophilus parasuis SH0165 glutamate-1-semialdehyde 2,1-aminomutase YP_002476224.1 1737241 D 557723 CDS YP_002476225.1 219871850 7277678 complement(1738672..1739955) 1 NC_011852.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1739955 hemL 7277678 hemL Haemophilus parasuis SH0165 glutamate-1-semialdehyde aminotransferase YP_002476225.1 1738672 R 557723 CDS YP_002476226.1 219871851 7277679 1740101..1741165 1 NC_011852.1 COG:M;COG0472; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1741165 wecA 7277679 wecA Haemophilus parasuis SH0165 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_002476226.1 1740101 D 557723 CDS YP_002476227.1 219871852 7277680 1741178..1741429 1 NC_011852.1 hypothetical protein 1741429 7277680 HAPS_1767 Haemophilus parasuis SH0165 hypothetical protein YP_002476227.1 1741178 D 557723 CDS YP_002476228.1 219871853 7277681 1741484..1742584 1 NC_011852.1 COG:M;COG0381; UDP-N-acetylglucosamine 2-epimerase 1742584 wecB 7277681 wecB Haemophilus parasuis SH0165 UDP-N-acetylglucosamine 2-epimerase YP_002476228.1 1741484 D 557723 CDS YP_002476229.1 219871854 7277682 1742571..1743815 1 NC_011852.1 COG:M;COG0677; UDP-N-acetyl-D-mannosamine dehydrogenase 1743815 wecC 7277682 wecC Haemophilus parasuis SH0165 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002476229.1 1742571 D 557723 CDS YP_002476230.1 219871855 7277683 1743906..1745627 1 NC_011852.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 1745627 dipZ 7277683 dipZ Haemophilus parasuis SH0165 thiol:disulfide interchange protein YP_002476230.1 1743906 D 557723 CDS YP_002476231.1 219871856 7277684 1745603..1746445 1 NC_011852.1 related to short-chain alcohol dehydrogenases; COG:IQR;COG1028; dehydrogenases with different specificities 1746445 7277684 HAPS_1771 Haemophilus parasuis SH0165 dehydrogenases with different specificities YP_002476231.1 1745603 D 557723 CDS YP_002476232.1 219871857 7277685 1746784..1747707 1 NC_011852.1 COG:L;COG2826; ISApl1, family IS30 1747707 7277685 HAPS_1772 Haemophilus parasuis SH0165 ISApl1, family IS30 YP_002476232.1 1746784 D 557723 CDS YP_002476233.1 219871858 7277686 complement(1747804..1749162) 1 NC_011852.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1749162 trmE 7277686 trmE Haemophilus parasuis SH0165 tRNA modification GTPase TrmE YP_002476233.1 1747804 R 557723 CDS YP_002476234.1 219871859 7277687 1749394..1749579 1 NC_011852.1 hypothetical protein 1749579 7277687 HAPS_1774 Haemophilus parasuis SH0165 hypothetical protein YP_002476234.1 1749394 D 557723 CDS YP_002476235.1 219871860 7277689 complement(1750920..1751396) 1 NC_011852.1 integral membrane protein 1751396 7277689 HAPS_1776 Haemophilus parasuis SH0165 integral membrane protein YP_002476235.1 1750920 R 557723 CDS YP_002476236.1 219871861 7277690 complement(1751492..1751896) 1 NC_011852.1 COG:E;COG0757; 3-dehydroquinate dehydratase 1751896 aroQ 7277690 aroQ Haemophilus parasuis SH0165 3-dehydroquinate dehydratase YP_002476236.1 1751492 R 557723 CDS YP_002476237.1 219871862 7277691 complement(1752230..1752910) 1 NC_011852.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1752910 ulaD 7277691 ulaD Haemophilus parasuis SH0165 3-keto-L-gulonate-6-phosphate decarboxylase YP_002476237.1 1752230 R 557723 CDS YP_002476238.1 219871863 7277692 complement(1753142..1753612) 1 NC_011852.1 COG:GT;COG1762; ascorbate-specific phosphotransferase protein IIA component, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) 1753612 ulaC 7277692 ulaC Haemophilus parasuis SH0165 ascorbate-specific phosphotransferase protein IIA component, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) YP_002476238.1 1753142 R 557723 CDS YP_002476239.1 219871864 7277693 complement(1753664..1755460) 1 NC_011852.1 COG:S;COG3037; PTS system ascorbate-specific transporter subunits IICB 1755460 ulaA 7277693 ulaA Haemophilus parasuis SH0165 PTS system ascorbate-specific transporter subunits IICB YP_002476239.1 1753664 R 557723 CDS YP_002476240.1 219871865 7277694 1755789..1756649 1 NC_011852.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 1756649 sgbU 7277694 sgbU Haemophilus parasuis SH0165 putative L-xylulose 5-phosphate 3-epimerase YP_002476240.1 1755789 D 557723 CDS YP_002476241.1 219871866 7277695 1756643..1757335 1 NC_011852.1 COG:G;COG0235; L-ribulose-5-phosphate 4-epimerase 1757335 sgbE 7277695 sgbE Haemophilus parasuis SH0165 L-ribulose-5-phosphate 4-epimerase YP_002476241.1 1756643 D 557723 CDS YP_002476242.1 219871867 7277697 complement(1758286..1758987) 1 NC_011852.1 hypothetical protein 1758987 7277697 HAPS_1784 Haemophilus parasuis SH0165 hypothetical protein YP_002476242.1 1758286 R 557723 CDS YP_002476243.1 219871868 7277698 complement(1759030..1759590) 1 NC_011852.1 COG:R;COG1611; decarboxylase 1759590 7277698 HAPS_1785 Haemophilus parasuis SH0165 decarboxylase YP_002476243.1 1759030 R 557723 CDS YP_002476244.1 219871869 7277699 1759654..1759974 1 NC_011852.1 COG:R;COG1694; nucleotide pyrophosphohydrolase 1759974 mazG 7277699 mazG Haemophilus parasuis SH0165 nucleotide pyrophosphohydrolase YP_002476244.1 1759654 D 557723 CDS YP_002476245.1 219871870 7277700 complement(1760032..1761381) 1 NC_011852.1 COG:GE;COG2610; gluconate permease 1761381 gntP 7277700 gntP Haemophilus parasuis SH0165 gluconate permease YP_002476245.1 1760032 R 557723 CDS YP_002476246.1 219871871 7277701 1761579..1762094 1 NC_011852.1 COG:G;COG3265; gluconate kinase 1762094 gntK 7277701 gntK Haemophilus parasuis SH0165 gluconate kinase YP_002476246.1 1761579 D 557723 CDS YP_002476247.1 219871872 7277702 complement(1762091..1763029) 1 NC_011852.1 COG:K;COG1609; HTH-type transcriptional regulator 1763029 gntR 7277702 gntR Haemophilus parasuis SH0165 HTH-type transcriptional regulator YP_002476247.1 1762091 R 557723 CDS YP_002476248.1 219871873 7277703 complement(1763227..1763817) 1 NC_011852.1 COG:C;COG3005; nitrate/TMAO reductase, membrane-bound tetraheme cytochrome c subunit 1763817 napC 7277703 napC Haemophilus parasuis SH0165 nitrate/TMAO reductase, membrane-bound tetraheme cytochrome c subunit YP_002476248.1 1763227 R 557723 CDS YP_002476249.1 219871874 7277704 complement(1763817..1764245) 1 NC_011852.1 COG:C;COG3043; diheme cytochrome c550/periplasmic nitrate reductase, small subunit, cytochrome C550, in complex with NapA 1764245 napB 7277704 napB Haemophilus parasuis SH0165 diheme cytochrome c550/periplasmic nitrate reductase, small subunit, cytochrome C550, in complex with NapA YP_002476249.1 1763817 R 557723 CDS YP_002476250.1 219871875 7277705 complement(1764242..1765111) 1 NC_011852.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 1765111 napH 7277705 napH Haemophilus parasuis SH0165 quinol dehydrogenase membrane component YP_002476250.1 1764242 R 557723 CDS YP_002476251.1 219871876 7277706 complement(1765111..1765800) 1 NC_011852.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 1765800 napG 7277706 napG Haemophilus parasuis SH0165 quinol dehydrogenase periplasmic component YP_002476251.1 1765111 R 557723 CDS YP_002476252.1 219871877 7277707 complement(1765962..1768445) 1 NC_011852.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 1768445 napA 7277707 napA Haemophilus parasuis SH0165 nitrate reductase catalytic subunit YP_002476252.1 1765962 R 557723 CDS YP_002476253.1 219871878 7277708 complement(1768478..1768762) 1 NC_011852.1 COG:P;COG3062; periplasmic nitrate reductase subunit NapD 1768762 napD 7277708 napD Haemophilus parasuis SH0165 periplasmic nitrate reductase subunit NapD YP_002476253.1 1768478 R 557723 CDS YP_002476254.1 219871879 7277709 complement(1768764..1769234) 1 NC_011852.1 COG:C;COG1145; ferredoxin-type protein NapF 1769234 napF 7277709 napF Haemophilus parasuis SH0165 ferredoxin-type protein NapF YP_002476254.1 1768764 R 557723 CDS YP_002476255.1 219871880 7277710 1769330..1769470 1 NC_011852.1 hypothetical protein 1769470 7277710 HAPS_1797 Haemophilus parasuis SH0165 hypothetical protein YP_002476255.1 1769330 D 557723 CDS YP_002476256.1 219871881 7277711 complement(1769488..1769613) 1 NC_011852.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1769613 rpmJ 7277711 rpmJ Haemophilus parasuis SH0165 50S ribosomal protein L36 YP_002476256.1 1769488 R 557723 CDS YP_002476257.1 219871882 7277712 complement(1769632..1769898) 1 NC_011852.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1769898 rpmE2 7277712 rpmE2 Haemophilus parasuis SH0165 50S ribosomal protein L31 YP_002476257.1 1769632 R 557723 CDS YP_002476258.1 219871883 7277713 1770112..1770786 1 NC_011852.1 COG:G;COG0036; ribulose-phosphate 3-epimerase 1770786 rpe 7277713 rpe Haemophilus parasuis SH0165 ribulose-phosphate 3-epimerase YP_002476258.1 1770112 D 557723 CDS YP_002476259.1 219871884 7277714 complement(1770861..1772309) 1 NC_011852.1 COG:P;COG3119; arylsulfatase A 1772309 7277714 HAPS_1801 Haemophilus parasuis SH0165 arylsulfatase A YP_002476259.1 1770861 R 557723 CDS YP_002476260.1 219871885 7277715 complement(1772403..1774094) 1 NC_011852.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK 1774094 yidK 7277715 yidK Haemophilus parasuis SH0165 putative symporter YidK YP_002476260.1 1772403 R 557723 CDS YP_002476261.1 219871886 7277716 1774347..1775153 1 NC_011852.1 COG:R;COG0730; permease 1775153 7277716 HAPS_1803 Haemophilus parasuis SH0165 permease YP_002476261.1 1774347 D 557723 CDS YP_002476262.1 219871887 7277717 1775277..1776167 1 NC_011852.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 1776167 oxyR 7277717 oxyR Haemophilus parasuis SH0165 DNA-binding transcriptional regulator OxyR YP_002476262.1 1775277 D 557723 CDS YP_002476263.1 219871888 7276678 1776167..1776784 1 NC_011852.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 1776784 fabR 7276678 fabR Haemophilus parasuis SH0165 DNA-binding transcriptional repressor FabR YP_002476263.1 1776167 D 557723 CDS YP_002476264.1 219871889 7278652 1776786..1777301 1 NC_011852.1 COG:OC;COG0526; thioredoxin-like protein 1777301 7278652 HAPS_1806 Haemophilus parasuis SH0165 thioredoxin-like protein YP_002476264.1 1776786 D 557723 CDS YP_002476265.1 219871890 7278653 complement(1777343..1777912) 1 NC_011852.1 COG:OC;COG0526; Thiol:disulfide interchange protein dsbA 1777912 dsbA 7278653 dsbA Haemophilus parasuis SH0165 Thiol:disulfide interchange protein dsbA YP_002476265.1 1777343 R 557723 CDS YP_002476266.1 219871891 7278654 complement(1778020..1778289) 1 NC_011852.1 COG:S;COG3084; hypothetical protein 1778289 7278654 HAPS_1808 Haemophilus parasuis SH0165 hypothetical protein YP_002476266.1 1778020 R 557723 CDS YP_002476267.1 219871892 7278655 1778374..1779486 1 NC_011852.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; MobB is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB 1779486 mobAB 7278655 mobAB Haemophilus parasuis SH0165 putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB YP_002476267.1 1778374 D 557723 CDS YP_002476268.1 219871893 7278656 complement(1780155..1780943) 1 NC_011852.1 COG:K;COG1414; transcriptional regulator IclR 1780943 iclR 7278656 iclR Haemophilus parasuis SH0165 transcriptional regulator IclR YP_002476268.1 1780155 R 557723 CDS YP_002476269.1 219871894 7278657 1781168..1781536 1 NC_011852.1 malate/L-lactate dehydrogenase 1781536 7278657 HAPS_1811 Haemophilus parasuis SH0165 malate/L-lactate dehydrogenase YP_002476269.1 1781168 D 557723 CDS YP_002476270.1 219871895 7278659 1782135..1783586 1 NC_011852.1 COG:G;COG1070; L-xylulose kinase 1783586 sgbK 7278659 sgbK Haemophilus parasuis SH0165 L-xylulose kinase YP_002476270.1 1782135 D 557723 CDS YP_002476271.1 219871896 7278662 complement(1784248..1784781) 1 NC_011852.1 COG:K;COG0250; transcription antitermination protein NusG 1784781 nusG 7278662 nusG Haemophilus parasuis SH0165 transcription antitermination protein NusG YP_002476271.1 1784248 R 557723 CDS YP_002476272.1 219871897 7278663 complement(1784828..1785238) 1 NC_011852.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1785238 secE 7278663 secE Haemophilus parasuis SH0165 preprotein translocase subunit SecE YP_002476272.1 1784828 R 557723 CDS YP_002476273.1 219871898 7278664 complement(1785493..1786938) 1 NC_011852.1 COG:R;COG0312; protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD 1786938 tldD 7278664 tldD Haemophilus parasuis SH0165 protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD YP_002476273.1 1785493 R 557723 CDS YP_002476274.1 219871899 7278665 complement(1786932..1787057) 1 NC_011852.1 hypothetical protein 1787057 7278665 HAPS_1819 Haemophilus parasuis SH0165 hypothetical protein YP_002476274.1 1786932 R 557723 CDS YP_002476275.1 219871900 7278666 1787069..1787896 1 NC_011852.1 COG:R;COG2819; alpha/beta superfamily hydrolase 1787896 7278666 HAPS_1820 Haemophilus parasuis SH0165 alpha/beta superfamily hydrolase YP_002476275.1 1787069 D 557723 CDS YP_002476276.1 219871901 7278667 1788043..1788282 1 NC_011852.1 COG:K;COG1396; XRE family transcriptional regulator 1788282 7278667 HAPS_1821 Haemophilus parasuis SH0165 XRE family transcriptional regulator YP_002476276.1 1788043 D 557723 CDS YP_002476277.1 219871902 7278668 1788276..1789592 1 NC_011852.1 COG:R;COG3550; HipA-like protein, regulator with hipB 1789592 hipA 7278668 hipA Haemophilus parasuis SH0165 HipA-like protein, regulator with hipB YP_002476277.1 1788276 D 557723 CDS YP_002476278.1 219871903 7278670 1790985..1791599 1 NC_011852.1 COG:O;COG3531; DSBA oxidoreductase 1791599 dsbA 7278670 dsbA Haemophilus parasuis SH0165 DSBA oxidoreductase YP_002476278.1 1790985 D 557723 CDS YP_002476279.1 219871904 7278671 complement(1791660..1792532) 1 NC_011852.1 COG:K;COG0583; LysR family transcriptional regulator 1792532 7278671 HAPS_1825 Haemophilus parasuis SH0165 LysR family transcriptional regulator YP_002476279.1 1791660 R 557723 CDS YP_002476280.1 219871905 7278672 complement(1792535..1795450) 1 NC_011852.1 COG:V;COG3587; Type III restriction-modification system EcoPI enzyme subunit res 1795450 7278672 HAPS_1826 Haemophilus parasuis SH0165 Type III restriction-modification system EcoPI enzyme subunit res YP_002476280.1 1792535 R 557723 CDS YP_002476281.1 219871906 7278673 complement(1795454..1797376) 1 NC_011852.1 COG:L;COG2189; Type III restriction-modification system EcoPI enzyme mod (M.EcoPI) (EcoPI methyltransferase) 1797376 7278673 HAPS_1827 Haemophilus parasuis SH0165 Type III restriction-modification system EcoPI enzyme mod (M.EcoPI) (EcoPI methyltransferase) YP_002476281.1 1795454 R 557723 CDS YP_002476282.1 219871907 7278674 complement(1797564..1798757) 1 NC_011852.1 COG:R;COG1373; putative ATPase (AAA+ superfamily) 1798757 7278674 HAPS_1828 Haemophilus parasuis SH0165 putative ATPase (AAA+ superfamily) YP_002476282.1 1797564 R 557723 CDS YP_002476283.1 219871908 7278675 1799185..1799397 1 NC_011852.1 hypothetical protein 1799397 7278675 HAPS_1829 Haemophilus parasuis SH0165 hypothetical protein YP_002476283.1 1799185 D 557723 CDS YP_002476284.1 219871909 7278676 complement(1799484..1799882) 1 NC_011852.1 COG:K;COG0789; MerR family transcriptional regulator 1799882 7278676 HAPS_1830 Haemophilus parasuis SH0165 MerR family transcriptional regulator YP_002476284.1 1799484 R 557723 CDS YP_002476285.1 219871910 7278677 1799952..1800566 1 NC_011852.1 COG:P;COG1230; Co/Zn/Cd efflux system component, CDF family cation diffusion facilitator 1800566 7278677 HAPS_1831 Haemophilus parasuis SH0165 Co/Zn/Cd efflux system component, CDF family cation diffusion facilitator YP_002476285.1 1799952 D 557723 CDS YP_002476286.1 219871911 7278678 complement(1800657..1801043) 1 NC_011852.1 COG:K;COG0789; MerR family transcriptional regulator 1801043 7278678 HAPS_1832 Haemophilus parasuis SH0165 MerR family transcriptional regulator YP_002476286.1 1800657 R 557723 CDS YP_002476287.1 219871912 7278679 complement(1801191..1801319) 1 NC_011852.1 hypothetical protein 1801319 7278679 HAPS_1833 Haemophilus parasuis SH0165 hypothetical protein YP_002476287.1 1801191 R 557723 CDS YP_002476288.1 219871913 7278680 1801437..1802183 1 NC_011852.1 COG:S;COG3544; hypothetical protein 1802183 7278680 HAPS_1834 Haemophilus parasuis SH0165 hypothetical protein YP_002476288.1 1801437 D 557723 CDS YP_002476289.1 219871914 7278681 1802365..1803312 1 NC_011852.1 COG:R;COG2070; 2-nitropropane dioxygenase 1803312 7278681 HAPS_1835 Haemophilus parasuis SH0165 2-nitropropane dioxygenase YP_002476289.1 1802365 D 557723 CDS YP_002476290.1 219871915 7278682 1803784..1804605 1 NC_011852.1 putative methionine sulfoxide reductase A 1804605 msrA 7278682 msrA Haemophilus parasuis SH0165 putative methionine sulfoxide reductase A YP_002476290.1 1803784 D 557723 CDS YP_002476291.1 219871916 7278683 1804753..1805775 1 NC_011852.1 COG:S;COG4804; putative cytoplasmic protein 1805775 7278683 HAPS_1837 Haemophilus parasuis SH0165 putative cytoplasmic protein YP_002476291.1 1804753 D 557723 CDS YP_002476292.1 219871917 7278685 complement(1806067..1806729) 1 NC_011852.1 COG:H;COG0352; thiamine-phosphate pyrophosphorylase 1806729 thiE 7278685 thiE Haemophilus parasuis SH0165 thiamine-phosphate pyrophosphorylase YP_002476292.1 1806067 R 557723 CDS YP_002476293.1 219871918 7278686 complement(1806746..1807546) 1 NC_011852.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1807546 thiD 7278686 thiD Haemophilus parasuis SH0165 phosphomethylpyrimidine kinase YP_002476293.1 1806746 R 557723 CDS YP_002476294.1 219871919 7278687 complement(1807557..1808366) 1 NC_011852.1 COG:H;COG2145; hydroxyethylthiazole kinase 1808366 thiM 7278687 thiM Haemophilus parasuis SH0165 hydroxyethylthiazole kinase YP_002476294.1 1807557 R 557723 CDS YP_002476295.1 219871920 7278689 complement(1810052..1811497) 1 NC_011852.1 COG:R;COG0312; protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD 1811497 tldD 7278689 tldD Haemophilus parasuis SH0165 protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD YP_002476295.1 1810052 R 557723 CDS YP_002476296.1 219871921 7278690 complement(1811491..1811616) 1 NC_011852.1 hypothetical protein 1811616 7278690 HAPS_1844 Haemophilus parasuis SH0165 hypothetical protein YP_002476296.1 1811491 R 557723 CDS YP_002476297.1 219871922 7278691 1811628..1812455 1 NC_011852.1 COG:R;COG2819; putative hydrolase of the alpha/beta superfamily 1812455 7278691 HAPS_1845 Haemophilus parasuis SH0165 putative hydrolase of the alpha/beta superfamily YP_002476297.1 1811628 D 557723 CDS YP_002476298.1 219871923 7278692 1812602..1812841 1 NC_011852.1 COG:K;COG1396; transcriptional regulator 1812841 hipB 7278692 hipB Haemophilus parasuis SH0165 transcriptional regulator YP_002476298.1 1812602 D 557723 CDS YP_002476299.1 219871924 7278693 1812835..1814151 1 NC_011852.1 COG:R;COG3550; HipA protein, co-regulate with HipB 1814151 hipA 7278693 hipA Haemophilus parasuis SH0165 HipA protein, co-regulate with HipB YP_002476299.1 1812835 D 557723 CDS YP_002476300.1 219871925 7278696 1816029..1816388 1 NC_011852.1 hypothetical protein 1816388 7278696 HAPS_1850 Haemophilus parasuis SH0165 hypothetical protein YP_002476300.1 1816029 D 557723 CDS YP_002476301.1 219871926 7278699 1817480..1817923 1 NC_011852.1 COG:S;COG4922; pyruvate kinase 1817923 pykF 7278699 pykF Haemophilus parasuis SH0165 pyruvate kinase YP_002476301.1 1817480 D 557723 CDS YP_002476302.1 219871927 7278701 complement(1818358..1818945) 1 NC_011852.1 COG:L;COG0742; N6-adenine-specific methylase 1818945 7278701 HAPS_1855 Haemophilus parasuis SH0165 N6-adenine-specific methylase YP_002476302.1 1818358 R 557723 CDS YP_002476303.1 219871928 7278702 1819044..1820411 1 NC_011852.1 COG:U;COG0552; cell division protein, signal recognition particle GTPase 1820411 ftsY 7278702 ftsY Haemophilus parasuis SH0165 cell division protein, signal recognition particle GTPase YP_002476303.1 1819044 D 557723 CDS YP_002476304.1 219871929 7278703 1820501..1821064 1 NC_011852.1 COG:D;COG2884; cell division ATP-binding protein 1821064 fstE 7278703 fstE Haemophilus parasuis SH0165 cell division ATP-binding protein YP_002476304.1 1820501 D 557723 CDS YP_002476305.1 219871930 7278707 complement(1824454..1824573) 1 NC_011852.1 hypothetical protein 1824573 7278707 HAPS_1861 Haemophilus parasuis SH0165 hypothetical protein YP_002476305.1 1824454 R 557723 CDS YP_002476306.1 219871931 7278708 1824766..1825380 1 NC_011852.1 COG:O;COG0625; glutathione S-transferase 1825380 gst 7278708 gst Haemophilus parasuis SH0165 glutathione S-transferase YP_002476306.1 1824766 D 557723 CDS YP_002476307.1 219871932 7278709 complement(1825415..1825957) 1 NC_011852.1 COG:R;COG3545; esterase of the alpha/beta hydrolase fold esterase 1825957 7278709 HAPS_1863 Haemophilus parasuis SH0165 esterase of the alpha/beta hydrolase fold esterase YP_002476307.1 1825415 R 557723 CDS YP_002476308.1 219871933 7278710 complement(1826042..1826800) 1 NC_011852.1 COG:KG;COG1349; glycerol-3-phosphate regulon repressor 1826800 glpR 7278710 glpR Haemophilus parasuis SH0165 glycerol-3-phosphate regulon repressor YP_002476308.1 1826042 R 557723 CDS YP_002476309.1 219871934 7278711 1826979..1827887 1 NC_011852.1 COG:I;COG2084; 3-hydroxyisobutyrate dehydrogenase 1827887 7278711 HAPS_1865 Haemophilus parasuis SH0165 3-hydroxyisobutyrate dehydrogenase YP_002476309.1 1826979 D 557723 CDS YP_002476310.1 219871935 7278712 1827889..1829130 1 NC_011852.1 COG:S;COG3395; Hrp-dependent type III effector protein 1829130 7278712 HAPS_1866 Haemophilus parasuis SH0165 Hrp-dependent type III effector protein YP_002476310.1 1827889 D 557723 CDS YP_002476311.1 219871936 7278713 1829127..1829759 1 NC_011852.1 COG:G;COG0235; putative aldolase 1829759 fucA 7278713 fucA Haemophilus parasuis SH0165 putative aldolase YP_002476311.1 1829127 D 557723 CDS YP_002476312.1 219871937 7278714 1829762..1830544 1 NC_011852.1 COG:G;COG3622; hydroxypyruvate isomerase 1830544 tsa 7278714 tsa Haemophilus parasuis SH0165 hydroxypyruvate isomerase YP_002476312.1 1829762 D 557723 CDS YP_002476313.1 219871938 7278715 1830569..1831516 1 NC_011852.1 COG:MG;COG0451; NAD-dependent epimerase/dehydratase 1831516 wbpK 7278715 wbpK Haemophilus parasuis SH0165 NAD-dependent epimerase/dehydratase YP_002476313.1 1830569 D 557723 CDS YP_002476314.1 219871939 7278716 1831528..1832994 1 NC_011852.1 COG:GE;COG2610; gluconate permease 1832994 gntP 7278716 gntP Haemophilus parasuis SH0165 gluconate permease YP_002476314.1 1831528 D 557723 CDS YP_002476315.1 219871940 7278717 1833054..1834400 1 NC_011852.1 COG:R;COG4099; phospholipase/carboxylesterase 1834400 7278717 HAPS_1871 Haemophilus parasuis SH0165 phospholipase/carboxylesterase YP_002476315.1 1833054 D 557723 CDS YP_002476316.1 219871941 7278719 complement(1835416..1835538) 1 NC_011852.1 hypothetical protein 1835538 7278719 HAPS_1873 Haemophilus parasuis SH0165 hypothetical protein YP_002476316.1 1835416 R 557723 CDS YP_002476317.1 219871942 7278721 complement(1836753..1838447) 1 NC_011852.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 1838447 dld 7278721 dld Haemophilus parasuis SH0165 D-lactate dehydrogenase YP_002476317.1 1836753 R 557723 CDS YP_002476318.1 219871943 7278727 complement(1844458..1845261) 1 NC_011852.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1845261 murI 7278727 murI Haemophilus parasuis SH0165 glutamate racemase YP_002476318.1 1844458 R 557723 CDS YP_002476319.1 219871944 7278728 complement(1845295..1845798) 1 NC_011852.1 COG:H;COG3161; 4-hydroxybenzoate synthetase 1845798 ubiC 7278728 ubiC Haemophilus parasuis SH0165 4-hydroxybenzoate synthetase YP_002476319.1 1845295 R 557723 CDS YP_002476320.1 219871945 7278729 complement(1845799..1846398) 1 NC_011852.1 COG:E;COG2755; N-acylneuraminate cytidylyltransferase/lysophospholipase L1-like protein 1846398 neuA 7278729 neuA Haemophilus parasuis SH0165 N-acylneuraminate cytidylyltransferase/lysophospholipase L1-like protein YP_002476320.1 1845799 R 557723 CDS YP_002476321.1 219871946 7278730 complement(1846437..1847465) 1 NC_011852.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1847465 trpS 7278730 trpS Haemophilus parasuis SH0165 tryptophanyl-tRNA synthetase YP_002476321.1 1846437 R 557723 CDS YP_002476322.1 219871947 7278731 complement(1847559..1849028) 1 NC_011852.1 COG:H;COG0043; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1849028 ubiD 7278731 ubiD Haemophilus parasuis SH0165 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002476322.1 1847559 R 557723 CDS YP_002476323.1 219871948 7278732 complement(1849188..1850324) 1 NC_011852.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1850324 dnaJ 7278732 dnaJ Haemophilus parasuis SH0165 chaperone protein DnaJ YP_002476323.1 1849188 R 557723 CDS YP_002476324.1 219871949 7278733 complement(1850377..1850802) 1 NC_011852.1 COG:S;COG3309; virulence-associated protein D 1850802 vapD 7278733 vapD Haemophilus parasuis SH0165 virulence-associated protein D YP_002476324.1 1850377 R 557723 CDS YP_002476325.1 219871950 7278734 complement(1850826..1850996) 1 NC_011852.1 hypothetical protein 1850996 7278734 HAPS_1888 Haemophilus parasuis SH0165 hypothetical protein YP_002476325.1 1850826 R 557723 CDS YP_002476326.1 219871951 7278735 complement(1851021..1852922) 1 NC_011852.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1852922 dnaK 7278735 dnaK Haemophilus parasuis SH0165 molecular chaperone DnaK YP_002476326.1 1851021 R 557723 CDS YP_002476327.1 219871952 7278736 complement(1853152..1854231) 1 NC_011852.1 COG:P;COG0387; calcium/proton antiporter 1854231 chaA 7278736 chaA Haemophilus parasuis SH0165 calcium/proton antiporter YP_002476327.1 1853152 R 557723 CDS YP_002476328.1 219871953 7278738 1855821..1856945 1 NC_011852.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1856945 carA 7278738 carA Haemophilus parasuis SH0165 carbamoyl phosphate synthase small subunit YP_002476328.1 1855821 D 557723 CDS YP_002476329.1 219871954 7278739 1857092..1860292 1 NC_011852.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1860292 carB 7278739 carB Haemophilus parasuis SH0165 carbamoyl phosphate synthase large subunit YP_002476329.1 1857092 D 557723 CDS YP_002476330.1 219871955 7278740 complement(1860356..1861549) 1 NC_011852.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1861549 nhaA 7278740 nhaA Haemophilus parasuis SH0165 pH-dependent sodium/proton antiporter YP_002476330.1 1860356 R 557723 CDS YP_002476331.1 219871956 7278741 1861837..1861971 1 NC_011852.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1861971 rpmH 7278741 rpmH Haemophilus parasuis SH0165 50S ribosomal protein L34 YP_002476331.1 1861837 D 557723 CDS YP_002476332.1 219871957 7278742 1861971..1862381 1 NC_011852.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1862381 rnpA 7278742 rnpA Haemophilus parasuis SH0165 ribonuclease P YP_002476332.1 1861971 D 557723 CDS YP_002476333.1 219871958 7278743 1862399..1862626 1 NC_011852.1 COG:S;COG0759; hypothetical protein 1862626 7278743 HAPS_1897 Haemophilus parasuis SH0165 hypothetical protein YP_002476333.1 1862399 D 557723 CDS YP_002476334.1 219871959 7278744 complement(1862655..1863263) 1 NC_011852.1 COG:S;COG1739; cell developmental protein SirA 1863263 sirA 7278744 sirA Haemophilus parasuis SH0165 cell developmental protein SirA YP_002476334.1 1862655 R 557723 CDS YP_002476335.1 219871960 7278745 1863489..1864448 1 NC_011852.1 COG:R;COG2358; TRAP transporter solute receptor TAXI family protein 1864448 7278745 HAPS_1899 Haemophilus parasuis SH0165 TRAP transporter solute receptor TAXI family protein YP_002476335.1 1863489 D 557723 CDS YP_002476336.1 219871961 7278746 1864590..1867268 1 NC_011852.1 COG:R;COG4666; TRAP dicarboxylate transporter subunit DctM 1867268 dctM 7278746 dctM Haemophilus parasuis SH0165 TRAP dicarboxylate transporter subunit DctM YP_002476336.1 1864590 D 557723 CDS YP_002476337.1 219871962 7278747 1867235..1867660 1 NC_011852.1 COG:T;COG0589; universal stress protein A 1867660 uspA 7278747 uspA Haemophilus parasuis SH0165 universal stress protein A YP_002476337.1 1867235 D 557723 CDS YP_002476338.1 219871963 7278748 1867873..1868178 1 NC_011852.1 COG:R;COG1669; DNA polymerase beta-like protein 1868178 7278748 HAPS_1902 Haemophilus parasuis SH0165 DNA polymerase beta-like protein YP_002476338.1 1867873 D 557723 CDS YP_002476339.1 219871964 7278749 1868425..1869390 1 NC_011852.1 COG:S;COG4804; hypothetical protein 1869390 7278749 HAPS_1903 Haemophilus parasuis SH0165 hypothetical protein YP_002476339.1 1868425 D 557723 CDS YP_002476340.1 219871965 7278750 complement(1869496..1869888) 1 NC_011852.1 COG:K;COG1396; transcriptional regulator 1869888 7278750 HAPS_1904 Haemophilus parasuis SH0165 transcriptional regulator YP_002476340.1 1869496 R 557723 CDS YP_002476341.1 219871966 7278751 1870008..1870634 1 NC_011852.1 phosphoglycolate phosphatase 1870634 gph 7278751 gph Haemophilus parasuis SH0165 phosphoglycolate phosphatase YP_002476341.1 1870008 D 557723 CDS YP_002476342.1 219871967 7278752 1870609..1871367 1 NC_011852.1 putative amidophosphoribosyltransferase 1871367 comFC 7278752 comFC Haemophilus parasuis SH0165 putative amidophosphoribosyltransferase YP_002476342.1 1870609 D 557723 CDS YP_002476343.1 219871968 7278753 1871378..1872373 1 NC_011852.1 DNA uptake Rossmann fold nucleotide-binding protein 1872373 smf 7278753 smf Haemophilus parasuis SH0165 DNA uptake Rossmann fold nucleotide-binding protein YP_002476343.1 1871378 D 557723 CDS YP_002476344.1 219871969 7278754 complement(1872464..1872883) 1 NC_011852.1 COG:R;COG1487; plasmid stability-like protein/nucleic acid-binding protein, contains PIN domain 1872883 pilT 7278754 pilT Haemophilus parasuis SH0165 plasmid stability-like protein/nucleic acid-binding protein, contains PIN domain YP_002476344.1 1872464 R 557723 CDS YP_002476345.1 219871970 7278755 complement(1872892..1873158) 1 NC_011852.1 prevent-host-death family protein/antitoxin of toxin-antitoxin stability system 1873158 7278755 HAPS_1909 Haemophilus parasuis SH0165 prevent-host-death family protein/antitoxin of toxin-antitoxin stability system YP_002476345.1 1872892 R 557723 CDS YP_002476346.1 219871971 7278756 1873340..1874290 1 NC_011852.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1874290 fmt 7278756 fmt Haemophilus parasuis SH0165 methionyl-tRNA formyltransferase YP_002476346.1 1873340 D 557723 CDS YP_002476347.1 219871972 7278757 1874290..1875588 1 NC_011852.1 COG:J;COG0144; ribosomal RNA small subunit methyltransferase B 1875588 rsmB 7278757 rsmB Haemophilus parasuis SH0165 ribosomal RNA small subunit methyltransferase B YP_002476347.1 1874290 D 557723 CDS YP_002476348.1 219871973 7278758 1875604..1876980 1 NC_011852.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1876980 trkA 7278758 trkA Haemophilus parasuis SH0165 potassium transporter peripheral membrane protein YP_002476348.1 1875604 D 557723 CDS YP_002476349.1 219871974 7278759 1877879..1878988 1 NC_011852.1 COG:E;COG0686; alanine dehydrogenase 1878988 ald 7278759 ald Haemophilus parasuis SH0165 alanine dehydrogenase YP_002476349.1 1877879 D 557723 CDS YP_002476350.1 219871975 7278760 1879146..1880507 1 NC_011852.1 COG:R;COG0733; SNF family Na+-dependent transporter 1880507 7278760 HAPS_1914 Haemophilus parasuis SH0165 SNF family Na+-dependent transporter YP_002476350.1 1879146 D 557723 CDS YP_002476351.1 219871976 7278761 1880563..1880676 1 NC_011852.1 hypothetical protein 1880676 7278761 HAPS_1915 Haemophilus parasuis SH0165 hypothetical protein YP_002476351.1 1880563 D 557723 CDS YP_002476352.1 219871977 7278762 complement(1880783..1881919) 1 NC_011852.1 ISRssp2, family IS1595 1881919 7278762 HAPS_1916 Haemophilus parasuis SH0165 ISRssp2, family IS1595 YP_002476352.1 1880783 R 557723 CDS YP_002476353.1 219871978 7278763 complement(1882112..1883563) 1 NC_011852.1 type II restriction enzyme HgaI 1883563 hgaI 7278763 hgaI Haemophilus parasuis SH0165 type II restriction enzyme HgaI YP_002476353.1 1882112 R 557723 CDS YP_002476354.1 219871979 7278764 complement(1883553..1884629) 1 NC_011852.1 COG:L;COG0270; moodification methylase HgaIA 1884629 7278764 HAPS_1918 Haemophilus parasuis SH0165 moodification methylase HgaIA YP_002476354.1 1883553 R 557723 CDS YP_002476355.1 219871980 7278765 complement(1884619..1885692) 1 NC_011852.1 COG:L;COG0270; moodification methylase HgaIA 1885692 7278765 HAPS_1919 Haemophilus parasuis SH0165 moodification methylase HgaIA YP_002476355.1 1884619 R 557723 CDS YP_002476356.1 219871981 7278766 complement(1885939..1886241) 1 NC_011852.1 transcriptional regulator 1886241 7278766 HAPS_1920 Haemophilus parasuis SH0165 transcriptional regulator YP_002476356.1 1885939 R 557723 CDS YP_002476357.1 219871982 7278767 1886720..1887397 1 NC_011852.1 ISSst2, family IS1595 1887397 7278767 HAPS_1921 Haemophilus parasuis SH0165 ISSst2, family IS1595 YP_002476357.1 1886720 D 557723 CDS YP_002476358.1 219871983 7278768 1887397..1887840 1 NC_011852.1 DNA repair ATPase 1887840 7278768 HAPS_1922 Haemophilus parasuis SH0165 DNA repair ATPase YP_002476358.1 1887397 D 557723 CDS YP_002476359.1 219871984 7278769 complement(1887824..1888369) 1 NC_011852.1 hypothetical protein 1888369 7278769 HAPS_1923 Haemophilus parasuis SH0165 hypothetical protein YP_002476359.1 1887824 R 557723 CDS YP_002476360.1 219871985 7278770 complement(1888539..1890005) 1 NC_011852.1 COG:P;COG0168; trk-type K+ transport system, membrane component 1890005 trkG 7278770 trkG Haemophilus parasuis SH0165 trk-type K+ transport system, membrane component YP_002476360.1 1888539 R 557723 CDS YP_002476361.1 219871986 7278772 complement(1890500..1891345) 1 NC_011852.1 COG:R;COG0561; putative haloacid dehalogenase-like hydrolase 1891345 cof 7278772 cof Haemophilus parasuis SH0165 putative haloacid dehalogenase-like hydrolase YP_002476361.1 1890500 R 557723 CDS YP_002476362.1 219871987 7278773 1891980..1893419 1 NC_011852.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1893419 leuA 7278773 leuA Haemophilus parasuis SH0165 2-isopropylmalate synthase YP_002476362.1 1891980 D 557723 CDS YP_002476363.1 219871988 7278774 1893503..1894753 1 NC_011852.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1894753 pepT 7278774 pepT Haemophilus parasuis SH0165 peptidase T YP_002476363.1 1893503 D 557723 CDS YP_002476364.1 219871989 7278777 complement(1897732..1898085) 1 NC_011852.1 COG:J;COG0292; 50S ribosomal protein L20 1898085 rplT 7278777 rplT Haemophilus parasuis SH0165 50S ribosomal protein L20 YP_002476364.1 1897732 R 557723 CDS YP_002476365.1 219871990 7278779 complement(1898176..1898373) 1 NC_011852.1 COG:J;COG0291; 50S ribosomal protein L35 1898373 rpmI 7278779 rpmI Haemophilus parasuis SH0165 50S ribosomal protein L35 YP_002476365.1 1898176 R 557723 CDS YP_002476366.1 219871991 7278780 complement(1898473..1898952) 1 NC_011852.1 COG:J;COG0290; translation initiation factor IF-3 1898952 infC 7278780 infC Haemophilus parasuis SH0165 translation initiation factor IF-3 YP_002476366.1 1898473 R 557723 CDS YP_002476367.1 219871992 7278781 1899230..1900264 1 NC_011852.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1900264 gcp 7278781 gcp Haemophilus parasuis SH0165 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002476367.1 1899230 D 557723 CDS YP_002476368.1 219871993 7278782 complement(1900553..1901368) 1 NC_011852.1 catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1901368 aroE 7278782 aroE Haemophilus parasuis SH0165 shikimate 5-dehydrogenase YP_002476368.1 1900553 R 557723 CDS YP_002476369.1 219871994 7278783 complement(1901502..1901861) 1 NC_011852.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1901861 rplS 7278783 rplS Haemophilus parasuis SH0165 50S ribosomal protein L19 YP_002476369.1 1901502 R 557723 CDS YP_002476370.1 219871995 7278784 complement(1901886..1903064) 1 NC_011852.1 multidrug-efflux transporter 1903064 7278784 HAPS_1938 Haemophilus parasuis SH0165 multidrug-efflux transporter YP_002476370.1 1901886 R 557723 CDS YP_002476371.1 219871996 7278785 complement(1903057..1904097) 1 NC_011852.1 UBA/THIF-type NAD/FAD binding protein, bacteriocin biosynthesis protein 1904097 mccB 7278785 mccB Haemophilus parasuis SH0165 UBA/THIF-type NAD/FAD binding protein, bacteriocin biosynthesis protein YP_002476371.1 1903057 R 557723 CDS YP_002476372.1 219871997 7278786 complement(1904407..1904757) 1 NC_011852.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1904757 rplS 7278786 rplS Haemophilus parasuis SH0165 50S ribosomal protein L19 YP_002476372.1 1904407 R 557723 CDS YP_002476373.1 219871998 7278787 complement(1904771..1905538) 1 NC_011852.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1905538 trmD 7278787 trmD Haemophilus parasuis SH0165 tRNA (guanine-N(1)-)-methyltransferase YP_002476373.1 1904771 R 557723 CDS YP_002476374.1 219871999 7278788 complement(1905587..1906114) 1 NC_011852.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1906114 rimM 7278788 rimM Haemophilus parasuis SH0165 16S rRNA-processing protein RimM YP_002476374.1 1905587 R 557723 CDS YP_002476375.1 219872000 7278789 complement(1906142..1906390) 1 NC_011852.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1906390 rpsP 7278789 rpsP Haemophilus parasuis SH0165 30S ribosomal protein S16 YP_002476375.1 1906142 R 557723 CDS YP_002476376.1 219872001 7278790 complement(1906400..1906579) 1 NC_011852.1 hypothetical protein 1906579 7278790 HAPS_1944 Haemophilus parasuis SH0165 hypothetical protein YP_002476376.1 1906400 R 557723 CDS YP_002476377.1 219872002 7278791 complement(1906734..1908125) 1 NC_011852.1 COG:C;COG1757; Na+/H+ antiporter 1908125 nhaC 7278791 nhaC Haemophilus parasuis SH0165 Na+/H+ antiporter YP_002476377.1 1906734 R 557723 CDS YP_002476378.1 219872003 7278792 complement(1908365..1908739) 1 NC_011852.1 hypothetical protein 1908739 7278792 HAPS_1946 Haemophilus parasuis SH0165 hypothetical protein YP_002476378.1 1908365 R 557723 CDS YP_002476379.1 219872004 7278793 complement(1908693..1908836) 1 NC_011852.1 hypothetical protein 1908836 7278793 HAPS_1947 Haemophilus parasuis SH0165 hypothetical protein YP_002476379.1 1908693 R 557723 CDS YP_002476380.1 219872005 7278794 1908928..1909131 1 NC_011852.1 hypothetical protein 1909131 7278794 HAPS_1948 Haemophilus parasuis SH0165 hypothetical protein YP_002476380.1 1908928 D 557723 CDS YP_002476381.1 219872006 7278796 1910131..1911129 1 NC_011852.1 type I site-specific deoxyribonuclease S subunit, restriction modification system 1911129 hsdS 7278796 hsdS Haemophilus parasuis SH0165 type I site-specific deoxyribonuclease S subunit, restriction modification system YP_002476381.1 1910131 D 557723 CDS YP_002476382.1 219872007 7278797 1911148..1913706 1 NC_011852.1 Toll-interleukin receptor 1913706 tir 7278797 tir Haemophilus parasuis SH0165 Toll-interleukin receptor YP_002476382.1 1911148 D 557723 CDS YP_002476383.1 219872008 7278799 1916967..1917680 1 NC_011852.1 COG:R;COG1451; putative metal-dependent hydrolase 1917680 7278799 HAPS_1953 Haemophilus parasuis SH0165 putative metal-dependent hydrolase YP_002476383.1 1916967 D 557723 CDS YP_002476384.1 219872009 7278800 1917971..1918942 1 NC_011852.1 similar to modification methylase EcoRI (adenine-specificmethyltransferase EcoRI) (M.EcoRI); adenine-specific methyltransferase 1918942 ecoRIM 7278800 ecoRIM Haemophilus parasuis SH0165 adenine-specific methyltransferase YP_002476384.1 1917971 D 557723 CDS YP_002476385.1 219872010 7278801 1918974..1920086 1 NC_011852.1 HNH endonuclease 1920086 hnh 7278801 hnh Haemophilus parasuis SH0165 HNH endonuclease YP_002476385.1 1918974 D 557723 CDS YP_002476386.1 219872011 7278802 complement(1920208..1921278) 1 NC_011852.1 type IIS restriction enzyme protein 1921278 bcgIB 7278802 bcgIB Haemophilus parasuis SH0165 type IIS restriction enzyme protein YP_002476386.1 1920208 R 557723 CDS YP_002476387.1 219872012 7278805 complement(1922959..1923951) 1 NC_011852.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1923951 asnA 7278805 asnA Haemophilus parasuis SH0165 asparagine synthetase AsnA YP_002476387.1 1922959 R 557723 CDS YP_002476388.1 219872013 7278806 1924128..1924619 1 NC_011852.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 1924619 asnC 7278806 asnC Haemophilus parasuis SH0165 DNA-binding transcriptional regulator AsnC YP_002476388.1 1924128 D 557723 CDS YP_002476389.1 219872014 7278807 1924731..1925498 1 NC_011852.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 1925498 udp 7278807 udp Haemophilus parasuis SH0165 uridine phosphorylase YP_002476389.1 1924731 D 557723 CDS YP_002476390.1 219872015 7278808 1925672..1926001 1 NC_011852.1 COG:S;COG3085; hypothetical protein 1926001 7278808 HAPS_1962 Haemophilus parasuis SH0165 hypothetical protein YP_002476390.1 1925672 D 557723 CDS YP_002476391.1 219872016 7278809 1926054..1927163 1 NC_011852.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 1927163 trmA2 7278809 trmA2 Haemophilus parasuis SH0165 tRNA (uracil-5-)-methyltransferase YP_002476391.1 1926054 D 557723 CDS YP_002476392.1 219872017 7278812 1927778..1928152 1 NC_011852.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1928152 rpsL 7278812 rpsL Haemophilus parasuis SH0165 30S ribosomal protein S12 YP_002476392.1 1927778 D 557723 CDS YP_002476393.1 219872018 7278813 1928282..1928752 1 NC_011852.1 COG:J;COG0049; 30S ribosomal protein S7 1928752 rpsG 7278813 rpsG Haemophilus parasuis SH0165 30S ribosomal protein S7 YP_002476393.1 1928282 D 557723 CDS YP_002476394.1 219872019 7278814 1928850..1930952 1 NC_011852.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1930952 fusA 7278814 fusA Haemophilus parasuis SH0165 elongation factor G YP_002476394.1 1928850 D 557723 CDS YP_002476395.1 219872020 7278896 1931020..1932207 1 NC_011852.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1932207 tuf 7278896 tuf Haemophilus parasuis SH0165 elongation factor Tu YP_002476395.1 1931020 D 557723 CDS YP_002476396.1 219872021 7277349 complement(1933438..1934172) 1 NC_011852.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 1934172 rlmB 7277349 rlmB Haemophilus parasuis SH0165 23S rRNA (guanosine-2'-O-)-methyltransferase YP_002476396.1 1933438 R 557723 CDS YP_002476397.1 219872022 7277350 complement(1934310..1935899) 1 NC_011852.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1935899 prfC 7277350 prfC Haemophilus parasuis SH0165 peptide chain release factor 3 YP_002476397.1 1934310 R 557723 CDS YP_002476398.1 219872023 7277351 complement(1936027..1936716) 1 NC_011852.1 COG:T;COG0639; diadenosine tetraphosphatase 1936716 apaH 7277351 apaH Haemophilus parasuis SH0165 diadenosine tetraphosphatase YP_002476398.1 1936027 R 557723 CDS YP_002476399.1 219872024 7277352 complement(1936713..1937984) 1 NC_011852.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 1937984 nadR 7277352 nadR Haemophilus parasuis SH0165 nicotinamide-nucleotide adenylyltransferase YP_002476399.1 1936713 R 557723 CDS YP_002476400.1 219872025 7277353 1938239..1938424 1 NC_011852.1 COG:C;COG1145; 4Fe-4S ferredoxin 1938424 fdx 7277353 fdx Haemophilus parasuis SH0165 4Fe-4S ferredoxin YP_002476400.1 1938239 D 557723 CDS YP_002476401.1 219872026 7277354 complement(1938419..1938946) 1 NC_011852.1 COG:CH;COG4635; protoporphyrinogen oxidase 1938946 hemG 7277354 hemG Haemophilus parasuis SH0165 protoporphyrinogen oxidase YP_002476401.1 1938419 R 557723 CDS YP_002476402.1 219872027 7277355 1939123..1939842 1 NC_011852.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 1939842 aphA 7277355 aphA Haemophilus parasuis SH0165 acid phosphatase/phosphotransferase YP_002476402.1 1939123 D 557723 CDS YP_002476403.1 219872028 7277356 1940117..1944013 1 NC_011852.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 1944013 purL 7277356 purL Haemophilus parasuis SH0165 phosphoribosylformylglycinamidine synthase YP_002476403.1 1940117 D 557723 CDS YP_002476404.1 219872029 7277357 1944076..1944465 1 NC_011852.1 hypothetical protein 1944465 7277357 HAPS_1979 Haemophilus parasuis SH0165 hypothetical protein YP_002476404.1 1944076 D 557723 CDS YP_002476405.1 219872030 7277358 1944922..1945569 1 NC_011852.1 hypothetical protein 1945569 7277358 HAPS_1980 Haemophilus parasuis SH0165 hypothetical protein YP_002476405.1 1944922 D 557723 CDS YP_002476406.1 219872031 7277359 complement(1945679..1946566) 1 NC_011852.1 COG:S;COG2990; arginine ABC transporter membrane protein 1946566 lapB 7277359 lapB Haemophilus parasuis SH0165 arginine ABC transporter membrane protein YP_002476406.1 1945679 R 557723 CDS YP_002476407.1 219872032 7277360 complement(1946636..1949335) 1 NC_011852.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1949335 valS 7277360 valS Haemophilus parasuis SH0165 valyl-tRNA synthetase YP_002476407.1 1946636 R 557723 CDS YP_002476408.1 219872033 7277361 complement(1949436..1950431) 1 NC_011852.1 COG:L;COG0863; Modification methylase HindIII 1950431 hindIIIM 7277361 hindIIIM Haemophilus parasuis SH0165 Modification methylase HindIII YP_002476408.1 1949436 R 557723 CDS YP_002476409.1 219872034 7277363 complement(1951659..1951829) 1 NC_011852.1 hypothetical protein 1951829 7277363 HAPS_1985 Haemophilus parasuis SH0165 hypothetical protein YP_002476409.1 1951659 R 557723 CDS YP_002476410.1 219872035 7277364 complement(1951816..1952574) 1 NC_011852.1 COG:S;COG3177; filamentation induced by cAMP protein fic 1952574 fic 7277364 fic Haemophilus parasuis SH0165 filamentation induced by cAMP protein fic YP_002476410.1 1951816 R 557723 CDS YP_002476411.1 219872036 7277368 complement(1954212..1954343) 1 NC_011852.1 hypothetical protein 1954343 7277368 HAPS_1990 Haemophilus parasuis SH0165 hypothetical protein YP_002476411.1 1954212 R 557723 CDS YP_002476412.1 219872037 7277370 complement(1954871..1955695) 1 NC_011852.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1955695 trpA 7277370 trpA Haemophilus parasuis SH0165 tryptophan synthase subunit alpha YP_002476412.1 1954871 R 557723 CDS YP_002476413.1 219872038 7277371 complement(1955692..1956888) 1 NC_011852.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1956888 trpB 7277371 trpB Haemophilus parasuis SH0165 tryptophan synthase subunit beta YP_002476413.1 1955692 R 557723 CDS YP_002476414.1 219872039 7277372 complement(1956908..1958377) 1 NC_011852.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1958377 trpC 7277372 trpC Haemophilus parasuis SH0165 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002476414.1 1956908 R 557723 CDS YP_002476415.1 219872040 7277373 complement(1958390..1959391) 1 NC_011852.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1959391 trpD 7277373 trpD Haemophilus parasuis SH0165 anthranilate phosphoribosyltransferase YP_002476415.1 1958390 R 557723 CDS YP_002476416.1 219872041 7277374 complement(1959393..1959992) 1 NC_011852.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1959992 trpG 7277374 trpG Haemophilus parasuis SH0165 anthranilate synthase component II YP_002476416.1 1959393 R 557723 CDS YP_002476417.1 219872042 7277375 complement(1960005..1961546) 1 NC_011852.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1961546 trpE 7277375 trpE Haemophilus parasuis SH0165 anthranilate synthase component I YP_002476417.1 1960005 R 557723 CDS YP_002476418.1 219872043 7277376 complement(1961857..1963374) 1 NC_011852.1 COG:M;COG1368; sulfatase/phosphoglycerol transferase 1963374 7277376 HAPS_1998 Haemophilus parasuis SH0165 sulfatase/phosphoglycerol transferase YP_002476418.1 1961857 R 557723 CDS YP_002476419.1 219872044 7277379 complement(1964096..1965115) 1 NC_011852.1 COG:J;COG1187; ribosomal large subunit pseudouridine synthase B 1965115 rluB 7277379 rluB Haemophilus parasuis SH0165 ribosomal large subunit pseudouridine synthase B YP_002476419.1 1964096 R 557723 CDS YP_002476420.1 219872045 7277380 complement(1965283..1965903) 1 NC_011852.1 COG:J;COG0009; putative translation factor 1965903 sua5 7277380 sua5 Haemophilus parasuis SH0165 putative translation factor YP_002476420.1 1965283 R 557723 CDS YP_002476421.1 219872046 7277383 complement(1967115..1967504) 1 NC_011852.1 COG:R;COG2166; SufE protein probably involved in Fe-S center assembly 1967504 sufE 7277383 sufE Haemophilus parasuis SH0165 SufE protein probably involved in Fe-S center assembly YP_002476421.1 1967115 R 557723 CDS YP_002476422.1 219872047 7277384 1967605..1968186 1 NC_011852.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1968186 clpP 7277384 clpP Haemophilus parasuis SH0165 ATP-dependent Clp protease proteolytic subunit YP_002476422.1 1967605 D 557723 CDS YP_002476423.1 219872048 7277385 1968193..1969443 1 NC_011852.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1969443 clpX 7277385 clpX Haemophilus parasuis SH0165 ATP-dependent protease ATP-binding subunit ClpX YP_002476423.1 1968193 D 557723 CDS YP_002476424.1 219872049 7277386 complement(1969517..1970650) 1 NC_011852.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1970650 dapE 7277386 dapE Haemophilus parasuis SH0165 succinyl-diaminopimelate desuccinylase YP_002476424.1 1969517 R 557723 CDS YP_002476425.1 219872050 7277387 complement(1970734..1971402) 1 NC_011852.1 Tfp pilus assembly pathway, fimbrial leader peptidase PilD 1971402 pilD 7277387 pilD Haemophilus parasuis SH0165 Tfp pilus assembly pathway, fimbrial leader peptidase PilD YP_002476425.1 1970734 R 557723 CDS YP_002476426.1 219872051 7276677 complement(1971399..1972595) 1 NC_011852.1 COG:NU;COG1459; Tfp pilus assembly pathway, component PilC 1972595 pilC 7276677 pilC Haemophilus parasuis SH0165 Tfp pilus assembly pathway, component PilC YP_002476426.1 1971399 R 557723 CDS YP_002476427.1 219872052 7278126 complement(1972588..1973973) 1 NC_011852.1 COG:NU;COG2804; Tfp pilus assembly pathway, ATPase PilB 1973973 pilB 7278126 pilB Haemophilus parasuis SH0165 Tfp pilus assembly pathway, ATPase PilB YP_002476427.1 1972588 R 557723 CDS YP_002476428.1 219872053 7278127 complement(1974326..1974691) 1 NC_011852.1 COG:S;COG2852; DNA methyltransferase 1974691 7278127 HAPS_2012 Haemophilus parasuis SH0165 DNA methyltransferase YP_002476428.1 1974326 R 557723 CDS YP_002476429.1 219872054 7278128 complement(1974964..1975416) 1 NC_011852.1 COG:NU;COG4969; Tfp pilus assembly protein, major pilin PilA 1975416 pilA 7278128 pilA Haemophilus parasuis SH0165 Tfp pilus assembly protein, major pilin PilA YP_002476429.1 1974964 R 557723 CDS YP_002476430.1 219872055 7278129 1975604..1976980 1 NC_011852.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1976980 radA 7278129 radA Haemophilus parasuis SH0165 DNA repair protein RadA YP_002476430.1 1975604 D 557723 CDS YP_002476431.1 219872056 7278130 complement(1977033..1977659) 1 NC_011852.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1977659 gmk 7278130 gmk Haemophilus parasuis SH0165 guanylate kinase YP_002476431.1 1977033 R 557723 CDS YP_002476432.1 219872057 7278131 complement(1977728..1978699) 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 1978699 7278131 HAPS_2016 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002476432.1 1977728 R 557723 CDS YP_002476433.1 219872058 7278132 1978828..1978953 1 NC_011852.1 hypothetical protein 1978953 7278132 HAPS_2017 Haemophilus parasuis SH0165 hypothetical protein YP_002476433.1 1978828 D 557723 CDS YP_002476434.1 219872059 7278133 1978950..1980971 1 NC_011852.1 COG:L;COG0210; ATP-dependent DNA helicase 1980971 rep 7278133 rep Haemophilus parasuis SH0165 ATP-dependent DNA helicase YP_002476434.1 1978950 D 557723 CDS YP_002476435.1 219872060 7278134 complement(1980983..1981819) 1 NC_011852.1 hypothetical protein 1981819 7278134 HAPS_2019 Haemophilus parasuis SH0165 hypothetical protein YP_002476435.1 1980983 R 557723 CDS YP_002476436.1 219872061 7278143 complement(1992116..1992595) 1 NC_011852.1 COG:J;COG0219; putative tRNA/rRNA methyltransferase 1992595 yibK 7278143 yibK Haemophilus parasuis SH0165 putative tRNA/rRNA methyltransferase YP_002476436.1 1992116 R 557723 CDS YP_002476437.1 219872062 7278144 complement(1992599..1994776) 1 NC_011852.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1994776 rlmL 7278144 rlmL Haemophilus parasuis SH0165 23S rRNA m(2)G2445 methyltransferase YP_002476437.1 1992599 R 557723 CDS YP_002476438.1 219872063 7278145 complement(1994926..1995867) 1 NC_011852.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 1995867 rsmC 7278145 rsmC Haemophilus parasuis SH0165 16S ribosomal RNA m2G1207 methyltransferase YP_002476438.1 1994926 R 557723 CDS YP_002476439.1 219872064 7278146 1995950..1996363 1 NC_011852.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 1996363 holD 7278146 holD Haemophilus parasuis SH0165 DNA polymerase III subunit psi YP_002476439.1 1995950 D 557723 CDS YP_002476440.1 219872065 7278147 1996365..1996805 1 NC_011852.1 COG:M;COG0739; metallopeptidase peptidase 1996805 7278147 HAPS_2032 Haemophilus parasuis SH0165 metallopeptidase peptidase YP_002476440.1 1996365 D 557723 CDS YP_002476441.1 219872066 7278148 1997047..1997484 1 NC_011852.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 1997484 rimI 7278148 rimI Haemophilus parasuis SH0165 ribosomal-protein-alanine N-acetyltransferase YP_002476441.1 1997047 D 557723 CDS YP_002476442.1 219872067 7278149 1997596..1998939 1 NC_011852.1 COG:R;COG3550; HipA domain-containing protein 1998939 hipA 7278149 hipA Haemophilus parasuis SH0165 HipA domain-containing protein YP_002476442.1 1997596 D 557723 CDS YP_002476443.1 219872068 7278150 1998939..1999283 1 NC_011852.1 COG:K;COG1396; XRE family transcriptional regulator 1999283 7278150 HAPS_2035 Haemophilus parasuis SH0165 XRE family transcriptional regulator YP_002476443.1 1998939 D 557723 CDS YP_002476444.1 219872069 7278151 1999312..2000637 1 NC_011852.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2000637 srmB 7278151 srmB Haemophilus parasuis SH0165 ATP-dependent RNA helicase SrmB YP_002476444.1 1999312 D 557723 CDS YP_002476445.1 219872070 7278152 2000758..2001390 1 NC_011852.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 2001390 lolB 7278152 lolB Haemophilus parasuis SH0165 outer membrane lipoprotein LolB YP_002476445.1 2000758 D 557723 CDS YP_002476446.1 219872071 7278153 2001392..2002237 1 NC_011852.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2002237 ipk 7278153 ipk Haemophilus parasuis SH0165 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002476446.1 2001392 D 557723 CDS YP_002476447.1 219872072 7278154 2002265..2003215 1 NC_011852.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2003215 prsA 7278154 prsA Haemophilus parasuis SH0165 ribose-phosphate pyrophosphokinase YP_002476447.1 2002265 D 557723 CDS YP_002476448.1 219872073 7278155 2003458..2004465 1 NC_011852.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2004465 pyrD 7278155 pyrD Haemophilus parasuis SH0165 dihydroorotate dehydrogenase 2 YP_002476448.1 2003458 D 557723 CDS YP_002476449.1 219872074 7278156 complement(2004746..2004892) 1 NC_011852.1 hypothetical protein 2004892 7278156 HAPS_2041 Haemophilus parasuis SH0165 hypothetical protein YP_002476449.1 2004746 R 557723 CDS YP_002476450.1 219872075 7278157 complement(2004994..2005185) 1 NC_011852.1 hypothetical protein 2005185 7278157 HAPS_2042 Haemophilus parasuis SH0165 hypothetical protein YP_002476450.1 2004994 R 557723 CDS YP_002476451.1 219872076 7278158 complement(2005440..2006114) 1 NC_011852.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 2006114 crp 7278158 crp Haemophilus parasuis SH0165 cAMP-regulatory protein YP_002476451.1 2005440 R 557723 CDS YP_002476452.1 219872077 7278159 complement(2006181..2006405) 1 NC_011852.1 COG:S;COG3089; hypothetical protein 2006405 7278159 HAPS_2044 Haemophilus parasuis SH0165 hypothetical protein YP_002476452.1 2006181 R 557723 CDS YP_002476453.1 219872078 7278160 complement(2006413..2007018) 1 NC_011852.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 2007018 slmA 7278160 slmA Haemophilus parasuis SH0165 nucleoid occlusion protein YP_002476453.1 2006413 R 557723 CDS YP_002476454.1 219872079 7278161 complement(2007027..2007482) 1 NC_011852.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 2007482 dut 7278161 dut Haemophilus parasuis SH0165 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002476454.1 2007027 R 557723 CDS YP_002476455.1 219872080 7278162 complement(2007508..2007834) 1 NC_011852.1 hypothetical protein 2007834 7278162 HAPS_2047 Haemophilus parasuis SH0165 hypothetical protein YP_002476455.1 2007508 R 557723 CDS YP_002476456.1 219872081 7278163 complement(2007844..2008935) 1 NC_011852.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 2008935 dfp 7278163 dfp Haemophilus parasuis SH0165 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002476456.1 2007844 R 557723 CDS YP_002476457.1 219872082 7278164 2009339..2009932 1 NC_011852.1 COG:L;COG2003; DNA repair protein RadC 2009932 radC 7278164 radC Haemophilus parasuis SH0165 DNA repair protein RadC YP_002476457.1 2009339 D 557723 CDS YP_002476458.1 219872083 7278165 2010058..2010294 1 NC_011852.1 required for 70S ribosome assembly; 50S ribosomal protein L28 2010294 rpmB 7278165 rpmB Haemophilus parasuis SH0165 50S ribosomal protein L28 YP_002476458.1 2010058 D 557723 CDS YP_002476459.1 219872084 7278166 2010306..2010476 1 NC_011852.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2010476 rpmG 7278166 rpmG Haemophilus parasuis SH0165 50S ribosomal protein L33 YP_002476459.1 2010306 D 557723 CDS YP_002476460.1 219872085 7278168 2011670..2012035 1 NC_011852.1 COG:S;COG3111; OB-fold nucleic acid binding domain-containing protein 2012035 7278168 HAPS_2053 Haemophilus parasuis SH0165 OB-fold nucleic acid binding domain-containing protein YP_002476460.1 2011670 D 557723 CDS YP_002476461.1 219872086 7278169 2012096..2012767 1 NC_011852.1 COG:TK;COG0745; two component transcriptional regulator/response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 2012767 cheY 7278169 cheY Haemophilus parasuis SH0165 two component transcriptional regulator/response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_002476461.1 2012096 D 557723 CDS YP_002476462.1 219872087 7278170 2012754..2014154 1 NC_011852.1 COG:T;COG0642; sensor protein QseC/integral membrane sensor signal transduction histidine kinase 2014154 qseC 7278170 qseC Haemophilus parasuis SH0165 sensor protein QseC/integral membrane sensor signal transduction histidine kinase YP_002476462.1 2012754 D 557723 CDS YP_002476463.1 219872088 7278171 2014217..2014333 1 NC_011852.1 hypothetical protein 2014333 7278171 HAPS_2056 Haemophilus parasuis SH0165 hypothetical protein YP_002476463.1 2014217 D 557723 CDS YP_002476464.1 219872089 7278172 2014546..2014833 1 NC_011852.1 COG:O;COG0234; co-chaperonin GroES (HSP10) 2014833 groES 7278172 groES Haemophilus parasuis SH0165 co-chaperonin GroES (HSP10) YP_002476464.1 2014546 D 557723 CDS YP_002476465.1 219872090 7278173 2014944..2016587 1 NC_011852.1 COG:O;COG0459; chaperonin GroEL (HSP60 family) 2016587 groEL 7278173 groEL Haemophilus parasuis SH0165 chaperonin GroEL (HSP60 family) YP_002476465.1 2014944 D 557723 CDS YP_002476466.1 219872091 7278174 2016754..2017806 1 NC_011852.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 2017806 7278174 HAPS_2059 Haemophilus parasuis SH0165 galactose-1-phosphate uridylyltransferase YP_002476466.1 2016754 D 557723 CDS YP_002476467.1 219872092 7278175 2017882..2018391 1 NC_011852.1 COG:L;COG2963; ISHin1, family IS3 2018391 7278175 HAPS_2060 Haemophilus parasuis SH0165 ISHin1, family IS3 YP_002476467.1 2017882 D 557723 CDS YP_002476468.1 219872093 7278176 2018388..2019209 1 NC_011852.1 COG:L;COG2801; ISHin1, family IS3 2019209 7278176 HAPS_2061 Haemophilus parasuis SH0165 ISHin1, family IS3 YP_002476468.1 2018388 D 557723 CDS YP_002476469.1 219872094 7278179 complement(2023347..2023505) 1 NC_011852.1 hypothetical protein 2023505 7278179 HAPS_2064 Haemophilus parasuis SH0165 hypothetical protein YP_002476469.1 2023347 R 557723 CDS YP_002476470.1 219872095 7278180 complement(2023826..2024167) 1 NC_011852.1 COG:S;COG0316; iron-sulfur cluster insertion protein ErpA 2024167 erpA 7278180 erpA Haemophilus parasuis SH0165 iron-sulfur cluster insertion protein ErpA YP_002476470.1 2023826 R 557723 CDS YP_002476471.1 219872096 7278181 complement(2024278..2025453) 1 NC_011852.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 2025453 obgE 7278181 obgE Haemophilus parasuis SH0165 GTPase ObgE YP_002476471.1 2024278 R 557723 CDS YP_002476472.1 219872097 7278182 complement(2025478..2026410) 1 NC_011852.1 COG:GER;COG0697; drug/metabolite transporter (DMT) superfamily permease 2026410 7278182 HAPS_2067 Haemophilus parasuis SH0165 drug/metabolite transporter (DMT) superfamily permease YP_002476472.1 2025478 R 557723 CDS YP_002476473.1 219872098 7278183 complement(2026412..2027278) 1 NC_011852.1 COG:GER;COG0697; drug/metabolite transporter (DMT) superfamily permease 2027278 7278183 HAPS_2068 Haemophilus parasuis SH0165 drug/metabolite transporter (DMT) superfamily permease YP_002476473.1 2026412 R 557723 CDS YP_002476474.1 219872099 7278184 complement(2027419..2027676) 1 NC_011852.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 2027676 rpmA 7278184 rpmA Haemophilus parasuis SH0165 50S ribosomal protein L27 YP_002476474.1 2027419 R 557723 CDS YP_002476475.1 219872100 7278185 complement(2027697..2028008) 1 NC_011852.1 COG:J;COG0261; 50S ribosomal protein L21 2028008 rplU 7278185 rplU Haemophilus parasuis SH0165 50S ribosomal protein L21 YP_002476475.1 2027697 R 557723 CDS YP_002476476.1 219872101 7278186 complement(2028206..2029357) 1 NC_011852.1 COG:G;COG1820; N-acetylglucosamine-6-phosphate deacetylase 2029357 nagA 7278186 nagA Haemophilus parasuis SH0165 N-acetylglucosamine-6-phosphate deacetylase YP_002476476.1 2028206 R 557723 CDS YP_002476477.1 219872102 7278187 complement(2029367..2030161) 1 NC_011852.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 2030161 nagB 7278187 nagB Haemophilus parasuis SH0165 glucosamine-6-phosphate deaminase YP_002476477.1 2029367 R 557723 CDS YP_002476478.1 219872103 7278188 complement(2030561..2031385) 1 NC_011852.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 2031385 dapF 7278188 dapF Haemophilus parasuis SH0165 diaminopimelate epimerase YP_002476478.1 2030561 R 557723 CDS YP_002476479.1 219872104 7278189 2031538..2032860 1 NC_011852.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 2032860 dcuB 7278189 dcuB Haemophilus parasuis SH0165 anaerobic C4-dicarboxylate transporter YP_002476479.1 2031538 D 557723 CDS YP_002476480.1 219872105 7278190 complement(2033122..2034552) 1 NC_011852.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 2034552 panF 7278190 panF Haemophilus parasuis SH0165 sodium/panthothenate symporter YP_002476480.1 2033122 R 557723 CDS YP_002476481.1 219872106 7278191 complement(2034542..2034781) 1 NC_011852.1 COG:S;COG3924; hypothetical protein 2034781 7278191 HAPS_2076 Haemophilus parasuis SH0165 hypothetical protein YP_002476481.1 2034542 R 557723 CDS YP_002476482.1 219872107 7278192 complement(2034838..2035155) 1 NC_011852.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 2035155 metJ 7278192 metJ Haemophilus parasuis SH0165 transcriptional repressor protein MetJ YP_002476482.1 2034838 R 557723 CDS YP_002476483.1 219872108 7278193 2035490..2036455 1 NC_011852.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 2036455 corA 7278193 corA Haemophilus parasuis SH0165 magnesium/nickel/cobalt transporter CorA YP_002476483.1 2035490 D 557723 CDS YP_002476484.1 219872109 7278194 complement(2036567..2040220) 1 NC_011852.1 COG:LK;COG1197; transcription-repair coupling factor 2040220 mfd 7278194 mfd Haemophilus parasuis SH0165 transcription-repair coupling factor YP_002476484.1 2036567 R 557723 CDS YP_002476485.1 219872110 7278195 2040284..2041348 1 NC_011852.1 putative multidrug resistance protein mdtH 2041348 mdtH 7278195 mdtH Haemophilus parasuis SH0165 putative multidrug resistance protein mdtH YP_002476485.1 2040284 D 557723 CDS YP_002476486.1 219872111 7278196 complement(2041403..2042677) 1 NC_011852.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 2042677 thrC 7278196 thrC Haemophilus parasuis SH0165 threonine synthase YP_002476486.1 2041403 R 557723 CDS YP_002476487.1 219872112 7278198 2044443..2045072 1 NC_011852.1 COG:O;COG0545; FKBP-type peptidyl-prolyl cis-trans isomerase 2045072 fklB 7278198 fklB Haemophilus parasuis SH0165 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002476487.1 2044443 D 557723 CDS YP_002476488.1 219872113 7278199 complement(2045121..2045621) 1 NC_011852.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 2045621 tpx 7278199 tpx Haemophilus parasuis SH0165 thiol peroxidase YP_002476488.1 2045121 R 557723 CDS YP_002476489.1 219872114 7278200 complement(2045618..2045794) 1 NC_011852.1 hypothetical protein 2045794 7278200 HAPS_2086 Haemophilus parasuis SH0165 hypothetical protein YP_002476489.1 2045618 R 557723 CDS YP_002476490.1 219872115 7278202 2045775..2046497 1 NC_011852.1 COG:I;COG0204; 1-acyl-sn-glycerol-3-phosphate acyltransferase 2046497 plsC 7278202 plsC Haemophilus parasuis SH0165 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002476490.1 2045775 D 557723 CDS YP_002476491.1 219872116 7278201 2046499..2047908 1 NC_011852.1 COG:Q;COG2132; protein SufI /multicopper oxidase type 3 2047908 sufI 7278201 sufI Haemophilus parasuis SH0165 protein SufI /multicopper oxidase type 3 YP_002476491.1 2046499 D 557723 CDS YP_002476492.1 219872117 7278203 2048029..2048982 1 NC_011852.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 2048982 accA 7278203 accA Haemophilus parasuis SH0165 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002476492.1 2048029 D 557723 CDS YP_002476493.1 219872118 7278204 complement(2049419..2049604) 1 NC_011852.1 COG:S;COG5566; bacteriophage transcriptional regulator 2049604 7278204 HAPS_2089 Haemophilus parasuis SH0165 bacteriophage transcriptional regulator YP_002476493.1 2049419 R 557723 CDS YP_002476494.1 219872119 7278207 2050164..2051657 1 NC_011852.1 COG:G;COG1263; PTS system transporter subunit IIBC 2051657 ptsEII 7278207 ptsEII Haemophilus parasuis SH0165 PTS system transporter subunit IIBC YP_002476494.1 2050164 D 557723 CDS YP_002476495.1 219872120 7277388 complement(2051956..2052942) 1 NC_011852.1 COG:L;COG3547; ISIMb1, family IS110 2052942 7277388 HAPS_2093 Haemophilus parasuis SH0165 ISIMb1, family IS110 YP_002476495.1 2051956 R 557723 CDS YP_002476496.1 219872121 7278537 2055362..2056144 1 NC_011852.1 COG:ET;COG0834; amino acid ABC transporter substrate-binding protein 2056144 7278537 HAPS_2096 Haemophilus parasuis SH0165 amino acid ABC transporter substrate-binding protein YP_002476496.1 2055362 D 557723 CDS YP_002476497.1 219872122 7278538 2056212..2056850 1 NC_011852.1 COG:E;COG0765; amino acid ABC transporter permease 2056850 yckJ 7278538 yckJ Haemophilus parasuis SH0165 amino acid ABC transporter permease YP_002476497.1 2056212 D 557723 CDS YP_002476498.1 219872123 7278539 2056853..2057602 1 NC_011852.1 COG:E;COG1126; amino acid ABC transporter ATPase 2057602 yckI 7278539 yckI Haemophilus parasuis SH0165 amino acid ABC transporter ATPase YP_002476498.1 2056853 D 557723 CDS YP_002476499.1 219872124 7278541 2058101..2060143 1 NC_011852.1 COG:S;COG1479; hypothetical protein 2060143 7278541 HAPS_2100 Haemophilus parasuis SH0165 hypothetical protein YP_002476499.1 2058101 D 557723 CDS YP_002476500.1 219872125 7278542 complement(2060271..2061698) 1 NC_011852.1 COG:ER;COG0493; glutamate synthase (NADPH) subunit beta 2061698 gltD 7278542 gltD Haemophilus parasuis SH0165 glutamate synthase (NADPH) subunit beta YP_002476500.1 2060271 R 557723 CDS YP_002476501.1 219872126 7278543 complement(2061915..2065901) 1 NC_011852.1 COG:E;COG0069; glutamate synthase (ferredoxin) subunit alpha 2065901 gltB 7278543 gltB Haemophilus parasuis SH0165 glutamate synthase (ferredoxin) subunit alpha YP_002476501.1 2061915 R 557723 CDS YP_002476502.1 219872127 7278544 2065914..2066369 1 NC_011852.1 hypothetical protein 2066369 7278544 HAPS_2103 Haemophilus parasuis SH0165 hypothetical protein YP_002476502.1 2065914 D 557723 CDS YP_002476503.1 219872128 7278545 complement(2066507..2067493) 1 NC_011852.1 COG:L;COG3547; ISIMb1, family IS110 2067493 7278545 HAPS_2104 Haemophilus parasuis SH0165 ISIMb1, family IS110 YP_002476503.1 2066507 R 557723 CDS YP_002476504.1 219872129 7278551 complement(2074076..2074387) 1 NC_011852.1 COG:J;COG0251; putative translation initiation inhibitor, yjgF family 2074387 7278551 HAPS_2110 Haemophilus parasuis SH0165 putative translation initiation inhibitor, yjgF family YP_002476504.1 2074076 R 557723 CDS YP_002476505.1 219872130 7278552 complement(2074456..2075475) 1 NC_011852.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 2075475 ilvE 7278552 ilvE Haemophilus parasuis SH0165 branched-chain amino acid aminotransferase YP_002476505.1 2074456 R 557723 CDS YP_002476506.1 219872131 7278553 2075914..2076810 1 NC_011852.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 2076810 gcvA 7278553 gcvA Haemophilus parasuis SH0165 DNA-binding transcriptional activator GcvA YP_002476506.1 2075914 D 557723 CDS YP_002476507.1 219872132 7278554 2076832..2077506 1 NC_011852.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 2077506 7278554 HAPS_2113 Haemophilus parasuis SH0165 nucleotidase YP_002476507.1 2076832 D 557723 CDS YP_002476508.1 219872133 7278555 2077572..2078507 1 NC_011852.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 2078507 cysB 7278555 cysB Haemophilus parasuis SH0165 transcriptional regulator CysB YP_002476508.1 2077572 D 557723 CDS YP_002476509.1 219872134 7278556 2078611..2078952 1 NC_011852.1 putative outer membrane protein 2078952 7278556 HAPS_2115 Haemophilus parasuis SH0165 putative outer membrane protein YP_002476509.1 2078611 D 557723 CDS YP_002476510.1 219872135 7278557 2079490..2080179 1 NC_011852.1 COG:R;COG1409; cyclic 3',5'-adenosine monophosphate phosphodiesterase 2080179 icc 7278557 icc Haemophilus parasuis SH0165 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002476510.1 2079490 D 557723 CDS YP_002476511.1 219872136 7278558 complement(2080274..2081263) 1 NC_011852.1 COG:CHR;COG1052; D-lactate dehydrogenase 2081263 ldhA 7278558 ldhA Haemophilus parasuis SH0165 D-lactate dehydrogenase YP_002476511.1 2080274 R 557723 CDS YP_002476512.1 219872137 7278559 complement(2081273..2082340) 1 NC_011852.1 hypothetical protein 2082340 7278559 HAPS_2118 Haemophilus parasuis SH0165 hypothetical protein YP_002476512.1 2081273 R 557723 CDS YP_002476513.1 219872138 7278560 complement(2082337..2083299) 1 NC_011852.1 COG:L;COG0270; DNA-cytosine methyltransferase/C-5 cytosine-specific DNA methylase 2083299 dcm 7278560 dcm Haemophilus parasuis SH0165 DNA-cytosine methyltransferase/C-5 cytosine-specific DNA methylase YP_002476513.1 2082337 R 557723 CDS YP_002476514.1 219872139 7278561 complement(2083307..2084416) 1 NC_011852.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2084416 ispG 7278561 ispG Haemophilus parasuis SH0165 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002476514.1 2083307 R 557723 CDS YP_002476515.1 219872140 7278562 complement(2084418..2085500) 1 NC_011852.1 COG:S;COG1426; hypothetical protein 2085500 7278562 HAPS_2121 Haemophilus parasuis SH0165 hypothetical protein YP_002476515.1 2084418 R 557723 CDS YP_002476516.1 219872141 7278563 complement(2085636..2087501) 1 NC_011852.1 COG:OU;COG0616; protease IV, signal peptide peptidase 2087501 sppA 7278563 sppA Haemophilus parasuis SH0165 protease IV, signal peptide peptidase YP_002476516.1 2085636 R 557723 CDS YP_002476517.1 219872142 7278564 2087720..2089501 1 NC_011852.1 COG:V;COG1132; lipid transporter ATP-binding/permease 2089501 msbA 7278564 msbA Haemophilus parasuis SH0165 lipid transporter ATP-binding/permease YP_002476517.1 2087720 D 557723 CDS YP_002476518.1 219872143 7278565 2089641..2090324 1 NC_011852.1 COG:H;COG3201; nicotinamide mononucleotide ABC transporter membrane protein/ATP-binding protein 2090324 pnuC 7278565 pnuC Haemophilus parasuis SH0165 nicotinamide mononucleotide ABC transporter membrane protein/ATP-binding protein YP_002476518.1 2089641 D 557723 CDS YP_002476519.1 219872144 7278566 2090387..2091127 1 NC_011852.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2091127 yfgE 7278566 yfgE Haemophilus parasuis SH0165 DNA replication initiation factor YP_002476519.1 2090387 D 557723 CDS YP_002476520.1 219872145 7278567 2091128..2091754 1 NC_011852.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2091754 ccmA 7278567 ccmA Haemophilus parasuis SH0165 cytochrome c biogenesis protein CcmA YP_002476520.1 2091128 D 557723 CDS YP_002476521.1 219872146 7278568 2091764..2092426 1 NC_011852.1 COG:O;COG2386; cytochrome c-type biogenesis protein/heme exporter protein B 2092426 ccmB 7278568 ccmB Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein/heme exporter protein B YP_002476521.1 2091764 D 557723 CDS YP_002476522.1 219872147 7278569 2092473..2093213 1 NC_011852.1 COG:O;COG0755; cytochrome c-type biogenesis protein/heme exporter protein C 2093213 ccmC 7278569 ccmC Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein/heme exporter protein C YP_002476522.1 2092473 D 557723 CDS YP_002476523.1 219872148 7278570 2093222..2093416 1 NC_011852.1 COG:U;COG3114; cytochrome c-type biogenesis protein/heme exporter protein D 2093416 ccmD 7278570 ccmD Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein/heme exporter protein D YP_002476523.1 2093222 D 557723 CDS YP_002476524.1 219872149 7278571 2093581..2094969 1 NC_011852.1 COG:P;COG0471; di- and tricarboxylate transporter 2094969 7278571 HAPS_2130 Haemophilus parasuis SH0165 di- and tricarboxylate transporter YP_002476524.1 2093581 D 557723 CDS YP_002476525.1 219872150 7278572 2095370..2096383 1 NC_011852.1 COG:G;COG0126; phosphoglycerate kinase 2096383 pgk 7278572 pgk Haemophilus parasuis SH0165 phosphoglycerate kinase YP_002476525.1 2095370 D 557723 CDS YP_002476526.1 219872151 7278573 complement(2096428..2096547) 1 NC_011852.1 hypothetical protein 2096547 7278573 HAPS_2133 Haemophilus parasuis SH0165 hypothetical protein YP_002476526.1 2096428 R 557723 CDS YP_002476527.1 219872152 7278575 2096528..2097607 1 NC_011852.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 2097607 fba 7278575 fba Haemophilus parasuis SH0165 fructose-bisphosphate aldolase YP_002476527.1 2096528 D 557723 CDS YP_002476528.1 219872153 7278574 2097780..2098580 1 NC_011852.1 COG:V;COG4167; peptide transport system ATP-binding protein SapF 2098580 sapF 7278574 sapF Haemophilus parasuis SH0165 peptide transport system ATP-binding protein SapF YP_002476528.1 2097780 D 557723 CDS YP_002476529.1 219872154 7278576 2098593..2099231 1 NC_011852.1 COG:C;COG0778; putative NAD(P)H nitroreductase 2099231 7278576 HAPS_2135 Haemophilus parasuis SH0165 putative NAD(P)H nitroreductase YP_002476529.1 2098593 D 557723 CDS YP_002476530.1 219872155 7278577 2099320..2099853 1 NC_011852.1 COG:S;COG2862; hypothetical protein 2099853 7278577 HAPS_2136 Haemophilus parasuis SH0165 hypothetical protein YP_002476530.1 2099320 D 557723 CDS YP_002476531.1 219872156 7278578 complement(2099938..2101236) 1 NC_011852.1 COG:E;COG0665; oxidoreductase OrdL 2101236 ordL 7278578 ordL Haemophilus parasuis SH0165 oxidoreductase OrdL YP_002476531.1 2099938 R 557723 CDS YP_002476532.1 219872157 7278582 complement(2101770..2102249) 1 NC_011852.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 2102249 greB 7278582 greB Haemophilus parasuis SH0165 transcription elongation factor GreB YP_002476532.1 2101770 R 557723 CDS YP_002476533.1 219872158 7278583 complement(2102249..2103184) 1 NC_011852.1 COG:M;COG0794; arabinose-5-phosphate isomerase 2103184 kpsF 7278583 kpsF Haemophilus parasuis SH0165 arabinose-5-phosphate isomerase YP_002476533.1 2102249 R 557723 CDS YP_002476534.1 219872159 7278584 complement(2103246..2103827) 1 NC_011852.1 COG:NU;COG3063; fimbrial biogenesis and twitching motility protein PilF-like protein 2103827 pilF 7278584 pilF Haemophilus parasuis SH0165 fimbrial biogenesis and twitching motility protein PilF-like protein YP_002476534.1 2103246 R 557723 CDS YP_002476535.1 219872160 7278585 complement(2103875..2104846) 1 NC_011852.1 COG:L;COG3547; ISNme5, family IS110 2104846 7278585 HAPS_2144 Haemophilus parasuis SH0165 ISNme5, family IS110 YP_002476535.1 2103875 R 557723 CDS YP_002476536.1 219872161 7278586 complement(2105089..2106249) 1 NC_011852.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2106249 7278586 HAPS_2145 Haemophilus parasuis SH0165 ribosomal RNA large subunit methyltransferase N YP_002476536.1 2105089 R 557723 CDS YP_002476537.1 219872162 7278587 complement(2106450..2106758) 1 NC_011852.1 COG:K;COG2944; DNA-binding protein, virulence gene repressor RsaL 2106758 rsaL 7278587 rsaL Haemophilus parasuis SH0165 DNA-binding protein, virulence gene repressor RsaL YP_002476537.1 2106450 R 557723 CDS YP_002476538.1 219872163 7278588 complement(2106864..2107100) 1 NC_011852.1 COG:JD;COG2026; hypothetical protein 2107100 7278588 HAPS_2147 Haemophilus parasuis SH0165 hypothetical protein YP_002476538.1 2106864 R 557723 CDS YP_002476539.1 219872164 7278593 2107934..2109373 1 NC_011852.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2109373 gltX 7278593 gltX Haemophilus parasuis SH0165 glutamyl-tRNA synthetase YP_002476539.1 2107934 D 557723 CDS YP_002476540.1 219872165 7278595 complement(2109858..2111987) 1 NC_011852.1 COG:P;COG2217; copper-transporting P-type ATPase 2111987 copA 7278595 copA Haemophilus parasuis SH0165 copper-transporting P-type ATPase YP_002476540.1 2109858 R 557723 CDS YP_002476541.1 219872166 7278597 complement(2112007..2112381) 1 NC_011852.1 COG:C;COG3783; soluble cytochrome b562 2112381 cybC 7278597 cybC Haemophilus parasuis SH0165 soluble cytochrome b562 YP_002476541.1 2112007 R 557723 CDS YP_002476542.1 219872167 7278598 complement(2112441..2113676) 1 NC_011852.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2113676 fabB 7278598 fabB Haemophilus parasuis SH0165 3-oxoacyl-ACP synthase YP_002476542.1 2112441 R 557723 CDS YP_002476543.1 219872168 7278599 complement(2113834..2116980) 1 NC_011852.1 COG:V;COG3587; type III restriction enzyme, res subunit 2116980 7278599 HAPS_2157 Haemophilus parasuis SH0165 type III restriction enzyme, res subunit YP_002476543.1 2113834 R 557723 CDS YP_002476544.1 219872169 7278600 complement(2116993..2118900) 1 NC_011852.1 COG:L;COG2189; type III restriction-modification system methyltransferase (adenine-specific)/adenine specific DNA methylase Mod 2118900 mod 7278600 mod Haemophilus parasuis SH0165 type III restriction-modification system methyltransferase (adenine-specific)/adenine specific DNA methylase Mod YP_002476544.1 2116993 R 557723 CDS YP_002476545.1 219872170 7278601 complement(2118937..2119242) 1 NC_011852.1 hypothetical protein 2119242 7278601 HAPS_2159 Haemophilus parasuis SH0165 hypothetical protein YP_002476545.1 2118937 R 557723 CDS YP_002476546.1 219872171 7278602 complement(2119686..2120984) 1 NC_011852.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 2120984 purA 7278602 purA Haemophilus parasuis SH0165 adenylosuccinate synthetase YP_002476546.1 2119686 R 557723 CDS YP_002476547.1 219872172 7278603 complement(2121267..2122154) 1 NC_011852.1 COG:O;COG0330; protein HflC/membrane protease subunit, stomatin/prohibitin-like protein 2122154 hflC 7278603 hflC Haemophilus parasuis SH0165 protein HflC/membrane protease subunit, stomatin/prohibitin-like protein YP_002476547.1 2121267 R 557723 CDS YP_002476548.1 219872173 7278604 complement(2122157..2123371) 1 NC_011852.1 COG:O;COG0330; protein HflK/membrane protease subunit, stomatin/prohibitin-like protein 2123371 hflK 7278604 hflK Haemophilus parasuis SH0165 protein HflK/membrane protease subunit, stomatin/prohibitin-like protein YP_002476548.1 2122157 R 557723 CDS YP_002476549.1 219872174 7278605 2123617..2124288 1 NC_011852.1 COG:KR;COG0454; TDP-fucosamine acetyltransferase 2124288 wecD 7278605 wecD Haemophilus parasuis SH0165 TDP-fucosamine acetyltransferase YP_002476549.1 2123617 D 557723 CDS YP_002476550.1 219872175 7278606 2124288..2125424 1 NC_011852.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 2125424 wecE 7278606 wecE Haemophilus parasuis SH0165 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_002476550.1 2124288 D 557723 CDS YP_002476551.1 219872176 7278609 complement(2126276..2127049) 1 NC_011852.1 putative iron compound ABC transporter permease 2127049 7278609 HAPS_2167 Haemophilus parasuis SH0165 putative iron compound ABC transporter permease YP_002476551.1 2126276 R 557723 CDS YP_002476552.1 219872177 7278610 2127236..2128624 1 NC_011852.1 COG:MU;COG1538; RND efflux system outer membrane lipoprotein/RND superfamily resistance-nodulation-cell division antiporter 2128624 tolC 7278610 tolC Haemophilus parasuis SH0165 RND efflux system outer membrane lipoprotein/RND superfamily resistance-nodulation-cell division antiporter YP_002476552.1 2127236 D 557723 CDS YP_002476553.1 219872178 7278611 complement(2128684..2129334) 1 NC_011852.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2129334 rnt 7278611 rnt Haemophilus parasuis SH0165 ribonuclease T YP_002476553.1 2128684 R 557723 CDS YP_002476554.1 219872179 7278612 complement(2129334..2129738) 1 NC_011852.1 COG:E;COG0346; lactoylglutathione lyase 2129738 glo1 7278612 glo1 Haemophilus parasuis SH0165 lactoylglutathione lyase YP_002476554.1 2129334 R 557723 CDS YP_002476555.1 219872180 7278613 2129819..2130643 1 NC_011852.1 DMT superfamily drug/metabolite transporter 2130643 7278613 HAPS_2171 Haemophilus parasuis SH0165 DMT superfamily drug/metabolite transporter YP_002476555.1 2129819 D 557723 CDS YP_002476556.1 219872181 7278614 2130692..2133361 1 NC_011852.1 hypothetical protein 2133361 7278614 HAPS_2172 Haemophilus parasuis SH0165 hypothetical protein YP_002476556.1 2130692 D 557723 CDS YP_002476557.1 219872182 7278208 2134368..2134682 1 NC_011852.1 COG:K;COG2944; XRE family transcriptional regulator 2134682 7278208 HAPS_2174 Haemophilus parasuis SH0165 XRE family transcriptional regulator YP_002476557.1 2134368 D 557723 CDS YP_002476558.1 219872183 7277718 2134880..2135062 1 NC_011852.1 hypothetical protein 2135062 7277718 HAPS_2175 Haemophilus parasuis SH0165 hypothetical protein YP_002476558.1 2134880 D 557723 CDS YP_002476559.1 219872184 7277719 complement(2135142..2137409) 1 NC_011852.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2137409 sfcA 7277719 sfcA Haemophilus parasuis SH0165 malic enzyme YP_002476559.1 2135142 R 557723 CDS YP_002476560.1 219872185 7277720 complement(2137699..2138025) 1 NC_011852.1 COG:O;COG0278; monothiol glutaredoxin-like protein 2138025 ydhD 7277720 ydhD Haemophilus parasuis SH0165 monothiol glutaredoxin-like protein YP_002476560.1 2137699 R 557723 CDS YP_002476561.1 219872186 7277721 complement(2138151..2140043) 1 NC_011852.1 COG:L;COG0507; ATP-dependent exonuclease V subunit alpha 2140043 recD 7277721 recD Haemophilus parasuis SH0165 ATP-dependent exonuclease V subunit alpha YP_002476561.1 2138151 R 557723 CDS YP_002476562.1 219872187 7277722 complement(2140202..2142328) 1 NC_011852.1 COG:P;COG1629; heme/hemopexin utilization protein C/outer membrane receptor protein 2142328 hxuC 7277722 hxuC Haemophilus parasuis SH0165 heme/hemopexin utilization protein C/outer membrane receptor protein YP_002476562.1 2140202 R 557723 CDS YP_002476563.1 219872188 7277723 2142475..2144169 1 NC_011852.1 COG:U;COG2831; heme/hemopexin-binding protein B, hemolysin activation/secretion protein 2144169 hxuB 7277723 hxuB Haemophilus parasuis SH0165 heme/hemopexin-binding protein B, hemolysin activation/secretion protein YP_002476563.1 2142475 D 557723 CDS YP_002476564.1 219872189 7277724 2144185..2147106 1 NC_011852.1 COG:U;COG3210; heme/hemopexin-binding protein A (Heme:hemopexin utilization protein A) 2147106 hxuA 7277724 hxuA Haemophilus parasuis SH0165 heme/hemopexin-binding protein A (Heme:hemopexin utilization protein A) YP_002476564.1 2144185 D 557723 CDS YP_002476565.1 219872190 7277725 complement(2147192..2148631) 1 NC_011852.1 COG:G;COG0469; pyruvate kinase 2148631 pykA 7277725 pykA Haemophilus parasuis SH0165 pyruvate kinase YP_002476565.1 2147192 R 557723 CDS YP_002476566.1 219872191 7277726 2148759..2149250 1 NC_011852.1 COG:T;COG2062; phosphohistidine phosphatase 2149250 sixA 7277726 sixA Haemophilus parasuis SH0165 phosphohistidine phosphatase YP_002476566.1 2148759 D 557723 CDS YP_002476567.1 219872192 7277727 2149398..2150762 1 NC_011852.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 2150762 uhpT 7277727 uhpT Haemophilus parasuis SH0165 sugar phosphate antiporter YP_002476567.1 2149398 D 557723 CDS YP_002476568.1 219872193 7277729 2151416..2152723 1 NC_011852.1 COG:T;COG3851; sensory histidine kinase UhpB/signal transduction histidine kinase, glucose-6-phosphate specific 2152723 uhpB 7277729 uhpB Haemophilus parasuis SH0165 sensory histidine kinase UhpB/signal transduction histidine kinase, glucose-6-phosphate specific YP_002476568.1 2151416 D 557723 CDS YP_002476569.1 219872194 7277731 complement(2153323..2154288) 1 NC_011852.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 2154288 pfkA 7277731 pfkA Haemophilus parasuis SH0165 6-phosphofructokinase YP_002476569.1 2153323 R 557723 CDS YP_002476570.1 219872195 7277732 complement(2154410..2155606) 1 NC_011852.1 COG:E;COG0520; cysteine desulfurase 2155606 nifS 7277732 nifS Haemophilus parasuis SH0165 cysteine desulfurase YP_002476570.1 2154410 R 557723 CDS YP_002476571.1 219872196 7277733 complement(2155603..2156292) 1 NC_011852.1 COG:L;COG1525; putative micrococcal nuclease (thermonuclease)-like protein 2156292 7277733 HAPS_2190 Haemophilus parasuis SH0165 putative micrococcal nuclease (thermonuclease)-like protein YP_002476571.1 2155603 R 557723 CDS YP_002476572.1 219872197 7277734 2156481..2157407 1 NC_011852.1 COG:K;COG0583; LysR family transcriptional regulator 2157407 metR 7277734 metR Haemophilus parasuis SH0165 LysR family transcriptional regulator YP_002476572.1 2156481 D 557723 CDS YP_002476573.1 219872198 7277735 complement(2157478..2158800) 1 NC_011852.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 2158800 pepQ 7277735 pepQ Haemophilus parasuis SH0165 proline dipeptidase YP_002476573.1 2157478 R 557723 CDS YP_002476574.1 219872199 7277736 2158836..2159084 1 NC_011852.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 2159084 sirA 7277736 sirA Haemophilus parasuis SH0165 sulfur transfer protein SirA YP_002476574.1 2158836 D 557723 CDS YP_002476575.1 219872200 7277737 complement(2159070..2160602) 1 NC_011852.1 methyltransferase type 11 2160602 7277737 HAPS_2194 Haemophilus parasuis SH0165 methyltransferase type 11 YP_002476575.1 2159070 R 557723 CDS YP_002476576.1 219872201 7277738 complement(2160683..2161105) 1 NC_011852.1 COG:S;COG3076; hypothetical protein 2161105 7277738 HAPS_2195 Haemophilus parasuis SH0165 hypothetical protein YP_002476576.1 2160683 R 557723 CDS YP_002476577.1 219872202 7277739 complement(2161110..2161739) 1 NC_011852.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 2161739 engB 7277739 engB Haemophilus parasuis SH0165 ribosome biogenesis GTP-binding protein YsxC YP_002476577.1 2161110 R 557723 CDS YP_002476578.1 219872203 7277740 complement(2161895..2162311) 1 NC_011852.1 COG:S;COG3152; hypothetical protein 2162311 7277740 HAPS_2197 Haemophilus parasuis SH0165 hypothetical protein YP_002476578.1 2161895 R 557723 CDS YP_002476579.1 219872204 7277741 complement(2162311..2164920) 1 NC_011852.1 COG:E;COG0308; aminopeptidase N 2164920 pepN 7277741 pepN Haemophilus parasuis SH0165 aminopeptidase N YP_002476579.1 2162311 R 557723 CDS YP_002476580.1 219872205 7277742 complement(2164988..2165671) 1 NC_011852.1 COG:R;COG0325; succinyl-diaminopimelate desuccinylase 2165671 dapE 7277742 dapE Haemophilus parasuis SH0165 succinyl-diaminopimelate desuccinylase YP_002476580.1 2164988 R 557723 CDS YP_002476581.1 219872206 7277743 2165739..2166278 1 NC_011852.1 COG:R;COG1778; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 2166278 kdsC 7277743 kdsC Haemophilus parasuis SH0165 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_002476581.1 2165739 D 557723 CDS YP_002476582.1 219872207 7277744 2166363..2166869 1 NC_011852.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 2166869 orn 7277744 orn Haemophilus parasuis SH0165 oligoribonuclease YP_002476582.1 2166363 D 557723 CDS YP_002476583.1 219872208 7277745 2166875..2167363 1 NC_011852.1 COG:R;COG0802; putative ATPase 2167363 7277745 HAPS_2202 Haemophilus parasuis SH0165 putative ATPase YP_002476583.1 2166875 D 557723 CDS YP_002476584.1 219872209 7277746 2167373..2168485 1 NC_011852.1 COG:M;COG0860; N-acetylmuramoyl-L-alanine amidase 2168485 amiB 7277746 amiB Haemophilus parasuis SH0165 N-acetylmuramoyl-L-alanine amidase YP_002476584.1 2167373 D 557723 CDS YP_002476585.1 219872210 7277747 2168606..2169265 1 NC_011852.1 sugar phosphate permease, required for N-linked glycosylation 2169265 7277747 HAPS_2204 Haemophilus parasuis SH0165 sugar phosphate permease, required for N-linked glycosylation YP_002476585.1 2168606 D 557723 CDS YP_002476586.1 219872211 7277748 complement(2169289..2169894) 1 NC_011852.1 COG:S;COG1434; hypothetical protein 2169894 7277748 HAPS_2205 Haemophilus parasuis SH0165 hypothetical protein YP_002476586.1 2169289 R 557723 CDS YP_002476587.1 219872212 7277749 2170291..2170845 1 NC_011852.1 COG:M;COG1083; acylneuraminate cytidylyltransferase/CMP-N-acetylneuraminic acid synthetase 2170845 neuA 7277749 neuA Haemophilus parasuis SH0165 acylneuraminate cytidylyltransferase/CMP-N-acetylneuraminic acid synthetase YP_002476587.1 2170291 D 557723 CDS YP_002476588.1 219872213 7277751 2171540..2172424 1 NC_011852.1 COG:M;COG0463; putative lipooligosaccharide galactosyltransferase involved in cell wall biogenesis 2172424 lsgE 7277751 lsgE Haemophilus parasuis SH0165 putative lipooligosaccharide galactosyltransferase involved in cell wall biogenesis YP_002476588.1 2171540 D 557723 CDS YP_002476589.1 219872214 7277752 2172424..2173224 1 NC_011852.1 COG:M;COG0463; putative UDP-galactose--lipooligosaccharide galactosyltransferase 2173224 lsgF 7277752 lsgF Haemophilus parasuis SH0165 putative UDP-galactose--lipooligosaccharide galactosyltransferase YP_002476589.1 2172424 D 557723 CDS YP_002476590.1 219872215 7277753 complement(2173353..2175293) 1 NC_011852.1 COG:O;COG1138; cytochrome c-type biogenesis protein CcmF 2175293 ccmF 7277753 ccmF Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein CcmF YP_002476590.1 2173353 R 557723 CDS YP_002476591.1 219872216 7277754 complement(2175290..2175823) 1 NC_011852.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2175823 ccmE 7277754 ccmE Haemophilus parasuis SH0165 cytochrome c-type biogenesis protein CcmE YP_002476591.1 2175290 R 557723 CDS YP_002476592.1 219872217 7277755 complement(2176350..2177723) 1 NC_011852.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 2177723 pntB 7277755 pntB Haemophilus parasuis SH0165 pyridine nucleotide transhydrogenase YP_002476592.1 2176350 R 557723 CDS YP_002476593.1 219872218 7277756 complement(2177735..2179267) 1 NC_011852.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 2179267 pntA 7277756 pntA Haemophilus parasuis SH0165 NAD(P) transhydrogenase subunit alpha YP_002476593.1 2177735 R 557723 CDS YP_002476594.1 219872219 7277757 2179319..2179438 1 NC_011852.1 hypothetical protein 2179438 7277757 HAPS_2214 Haemophilus parasuis SH0165 hypothetical protein YP_002476594.1 2179319 D 557723 CDS YP_002476595.1 219872220 7277758 2179546..2180598 1 NC_011852.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 2180598 mreB 7277758 mreB Haemophilus parasuis SH0165 rod shape-determining protein MreB YP_002476595.1 2179546 D 557723 CDS YP_002476596.1 219872221 7277759 2180792..2181739 1 NC_011852.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2181739 mreC 7277759 mreC Haemophilus parasuis SH0165 rod shape-determining protein MreC YP_002476596.1 2180792 D 557723 CDS YP_002476597.1 219872222 7277760 2181739..2182227 1 NC_011852.1 COG:M;COG2891; rod shape-determining protein MreD/Cell shape-determining protein 2182227 mreD 7277760 mreD Haemophilus parasuis SH0165 rod shape-determining protein MreD/Cell shape-determining protein YP_002476597.1 2181739 D 557723 CDS YP_002476598.1 219872223 7277761 2182227..2183570 1 NC_011852.1 COG:L;COG2256; recombination factor protein RarA 2183570 rarA 7277761 rarA Haemophilus parasuis SH0165 recombination factor protein RarA YP_002476598.1 2182227 D 557723 CDS YP_002476599.1 219872224 7277762 complement(2183573..2185033) 1 NC_011852.1 putative outer membrane protein 2185033 7277762 HAPS_2219 Haemophilus parasuis SH0165 putative outer membrane protein YP_002476599.1 2183573 R 557723 CDS YP_002476600.1 219872225 7277763 2185170..2185973 1 NC_011852.1 periplasmic protein, links inner and outer membranes 2185973 tonB 7277763 tonB Haemophilus parasuis SH0165 periplasmic protein, links inner and outer membranes YP_002476600.1 2185170 D 557723 CDS YP_002476601.1 219872226 7277764 2185991..2186659 1 NC_011852.1 COG:U;COG0811; biopolymer transport ExbB protein 2186659 exbB 7277764 exbB Haemophilus parasuis SH0165 biopolymer transport ExbB protein YP_002476601.1 2185991 D 557723 CDS YP_002476602.1 219872227 7277765 2186734..2187069 1 NC_011852.1 COG:U;COG0848; biopolymer transport ExbD protein 2187069 exbD 7277765 exbD Haemophilus parasuis SH0165 biopolymer transport ExbD protein YP_002476602.1 2186734 D 557723 CDS YP_002476603.1 219872228 7277766 2187280..2188740 1 NC_011852.1 transferrin-binding protein 2 2188740 tbpB 7277766 tbpB Haemophilus parasuis SH0165 transferrin-binding protein 2 YP_002476603.1 2187280 D 557723 CDS YP_002476604.1 219872229 7277767 2188754..2191456 1 NC_011852.1 COG:P;COG1629; transferrin-binding protein 1 2191456 tbpA 7277767 tbpA Haemophilus parasuis SH0165 transferrin-binding protein 1 YP_002476604.1 2188754 D 557723 CDS YP_002476605.1 219872230 7277768 complement(2191877..2192203) 1 NC_011852.1 COG:J;COG1544; sigma 54 modulation protein 2192203 7277768 HAPS_2225 Haemophilus parasuis SH0165 sigma 54 modulation protein YP_002476605.1 2191877 R 557723 CDS YP_002476606.1 219872231 7277769 2192377..2192688 1 NC_011852.1 hypothetical protein 2192688 7277769 HAPS_2226 Haemophilus parasuis SH0165 hypothetical protein YP_002476606.1 2192377 D 557723 CDS YP_002476607.1 219872232 7277770 2192688..2193623 1 NC_011852.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 2193623 lpxL 7277770 lpxL Haemophilus parasuis SH0165 lipid A biosynthesis lauroyl acyltransferase YP_002476607.1 2192688 D 557723 CDS YP_002476608.1 219872233 7277771 2193799..2194338 1 NC_011852.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 2194338 orfM 7277771 orfM Haemophilus parasuis SH0165 putative deoxyribonucleotide triphosphate pyrophosphatase YP_002476608.1 2193799 D 557723 CDS YP_002476609.1 219872234 7277772 2194346..2194531 1 NC_011852.1 COG:S;COG0393; hypothetical protein 2194531 7277772 HAPS_2229 Haemophilus parasuis SH0165 hypothetical protein YP_002476609.1 2194346 D 557723 CDS YP_002476610.1 219872235 7277773 2194531..2194986 1 NC_011852.1 COG:S;COG2983; hypothetical protein 2194986 7277773 HAPS_2230 Haemophilus parasuis SH0165 hypothetical protein YP_002476610.1 2194531 D 557723 CDS YP_002476611.1 219872236 7277774 complement(2195031..2197046) 1 NC_011852.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 2197046 uvrB 7277774 uvrB Haemophilus parasuis SH0165 excinuclease ABC subunit B YP_002476611.1 2195031 R 557723 CDS YP_002476612.1 219872237 7277775 2197225..2199801 1 NC_011852.1 COG:O;COG2844; PII uridylyl-transferase 2199801 glnD 7277775 glnD Haemophilus parasuis SH0165 PII uridylyl-transferase YP_002476612.1 2197225 D 557723 CDS YP_002476613.1 219872238 7277776 2200002..2200775 1 NC_011852.1 COG:V;COG4171; peptide transport system permease 2200775 sapC 7277776 sapC Haemophilus parasuis SH0165 peptide transport system permease YP_002476613.1 2200002 D 557723 CDS YP_002476614.1 219872239 7277777 2200788..2201819 1 NC_011852.1 COG:V;COG4170; peptide transport system ATP-binding protein 2201819 sapD 7277777 sapD Haemophilus parasuis SH0165 peptide transport system ATP-binding protein YP_002476614.1 2200788 D 557723 CDS YP_002476615.1 219872240 7277778 2202047..2203357 1 NC_011852.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2203357 eno 7277778 eno Haemophilus parasuis SH0165 phosphopyruvate hydratase YP_002476615.1 2202047 D 557723 CDS YP_002476616.1 219872241 7277779 2203727..2204218 1 NC_011852.1 COG:S;COG1666; nucleotide-binding protein 2204218 7277779 HAPS_2236 Haemophilus parasuis SH0165 nucleotide-binding protein YP_002476616.1 2203727 D 557723 CDS YP_002476617.1 219872242 7277780 2204336..2206237 1 NC_011852.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 2206237 parE 7277780 parE Haemophilus parasuis SH0165 DNA topoisomerase IV subunit B YP_002476617.1 2204336 D 557723 CDS YP_002476618.1 219872243 7277781 2206368..2207816 1 NC_011852.1 COG:P;COG0753; catalase 2207816 hktE 7277781 hktE Haemophilus parasuis SH0165 catalase YP_002476618.1 2206368 D 557723 CDS YP_002476619.1 219872244 7277782 2207911..2208996 1 NC_011852.1 COG:R;COG1408; phosphohydrolase 2208996 7277782 HAPS_2239 Haemophilus parasuis SH0165 phosphohydrolase YP_002476619.1 2207911 D 557723 CDS YP_002476620.1 219872245 7277783 complement(2209069..2209515) 1 NC_011852.1 COG:S;COG3120; hypothetical protein 2209515 7277783 HAPS_2240 Haemophilus parasuis SH0165 hypothetical protein YP_002476620.1 2209069 R 557723 CDS YP_002476621.1 219872246 7277784 2209592..2211226 1 NC_011852.1 COG:O;COG1067; putative S16 family lon protease, ATP-dependent protease 2211226 lonH 7277784 lonH Haemophilus parasuis SH0165 putative S16 family lon protease, ATP-dependent protease YP_002476621.1 2209592 D 557723 CDS YP_002476622.1 219872247 7277785 2211347..2211877 1 NC_011852.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 2211877 fabA 7277785 fabA Haemophilus parasuis SH0165 3-hydroxydecanoyl-ACP dehydratase YP_002476622.1 2211347 D 557723 CDS YP_002476623.1 219872248 7277786 2211966..2212475 1 NC_011852.1 Type II secretory pathway, pseudopilin PulG 2212475 pulG 7277786 pulG Haemophilus parasuis SH0165 Type II secretory pathway, pseudopilin PulG YP_002476623.1 2211966 D 557723 CDS YP_002476624.1 219872249 7277787 2212441..2213136 1 NC_011852.1 hypothetical protein 2213136 7277787 HAPS_2244 Haemophilus parasuis SH0165 hypothetical protein YP_002476624.1 2212441 D 557723 CDS YP_002476625.1 219872250 7277788 2213133..2213792 1 NC_011852.1 hypothetical protein 2213792 7277788 HAPS_2245 Haemophilus parasuis SH0165 hypothetical protein YP_002476625.1 2213133 D 557723 CDS YP_002476626.1 219872251 7277789 2213785..2214081 1 NC_011852.1 hypothetical protein 2214081 7277789 HAPS_2246 Haemophilus parasuis SH0165 hypothetical protein YP_002476626.1 2213785 D 557723 CDS YP_002476627.1 219872252 7277791 complement(2216465..2217856) 1 NC_011852.1 COG:V;COG0534; Drug:Na+ antiporter (norfloxacin, ethidium, kanamycin, ciprofloxin, streptomycin efflux pump) 2217856 norM 7277791 norM Haemophilus parasuis SH0165 Drug:Na+ antiporter (norfloxacin, ethidium, kanamycin, ciprofloxin, streptomycin efflux pump) YP_002476627.1 2216465 R 557723 CDS YP_002476628.1 219872253 7277792 complement(2217869..2218579) 1 NC_011852.1 COG:J;COG0564; pseudouridylate synthase, 23S RNA-specific 2218579 rluA 7277792 rluA Haemophilus parasuis SH0165 pseudouridylate synthase, 23S RNA-specific YP_002476628.1 2217869 R 557723 CDS YP_002476629.1 219872254 7277793 2218699..2219574 1 NC_011852.1 COG:P;COG3221; phosphate/phosphonate ABC transport system periplasmic phosphonate-binding protein 2219574 phnD 7277793 phnD Haemophilus parasuis SH0165 phosphate/phosphonate ABC transport system periplasmic phosphonate-binding protein YP_002476629.1 2218699 D 557723 CDS YP_002476630.1 219872255 7277794 2219840..2220592 1 NC_011852.1 COG:P;COG3638; phosphate/phosphonate ABC transporter ATPase 2220592 phnC 7277794 phnC Haemophilus parasuis SH0165 phosphate/phosphonate ABC transporter ATPase YP_002476630.1 2219840 D 557723 CDS YP_002476631.1 219872256 7277795 2220582..2221367 1 NC_011852.1 COG:P;COG3639; phosphate/phosphonate ABC transport system permease protein 2221367 phnE 7277795 phnE Haemophilus parasuis SH0165 phosphate/phosphonate ABC transport system permease protein YP_002476631.1 2220582 D 557723 CDS YP_002476632.1 219872257 7277796 2221364..2222212 1 NC_011852.1 COG:P;COG3639; phosphate/phosphonate ABC transport system inner membrane subunit 2222212 phnE 7277796 phnE Haemophilus parasuis SH0165 phosphate/phosphonate ABC transport system inner membrane subunit YP_002476632.1 2221364 D 557723 CDS YP_002476633.1 219872258 7277797 2222274..2222966 1 NC_011852.1 COG:S;COG2979; hypothetical protein 2222966 7277797 HAPS_2254 Haemophilus parasuis SH0165 hypothetical protein YP_002476633.1 2222274 D 557723 CDS YP_002476634.1 219872259 7277798 2223516..2224118 1 NC_011852.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 2224118 nudH 7277798 nudH Haemophilus parasuis SH0165 dinucleoside polyphosphate hydrolase YP_002476634.1 2223516 D 557723 CDS YP_002476635.1 219872260 7277552 2224115..2224912 1 NC_011852.1 COG:R;COG0730; permease 2224912 7277552 HAPS_2256 Haemophilus parasuis SH0165 permease YP_002476635.1 2224115 D 557723 CDS YP_002476636.1 219872261 7277223 2224922..2225725 1 NC_011852.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 2225725 lgt 7277223 lgt Haemophilus parasuis SH0165 prolipoprotein diacylglyceryl transferase YP_002476636.1 2224922 D 557723 CDS YP_002476637.1 219872262 7277224 2225922..2226215 1 NC_011852.1 LexA regulated protein 2226215 ybfE 7277224 ybfE Haemophilus parasuis SH0165 LexA regulated protein YP_002476637.1 2225922 D 557723 CDS YP_002476638.1 219872263 7277225 2226225..2226749 1 NC_011852.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 2226749 fldA 7277225 fldA Haemophilus parasuis SH0165 flavodoxin FldA YP_002476638.1 2226225 D 557723 CDS YP_002476639.1 219872264 7277226 2226769..2227215 1 NC_011852.1 COG:P;COG0735; ferric uptake regulation protein 2227215 fur 7277226 fur Haemophilus parasuis SH0165 ferric uptake regulation protein YP_002476639.1 2226769 D 557723 CDS YP_002476640.1 219872265 7277227 2227312..2229978 1 NC_011852.1 COG:R;COG3008; paraquat-inducible protein B 2229978 pqiB 7277227 pqiB Haemophilus parasuis SH0165 paraquat-inducible protein B YP_002476640.1 2227312 D 557723 CDS YP_002476641.1 219872266 7277228 2230025..2230186 1 NC_011852.1 hypothetical protein 2230186 7277228 HAPS_2262 Haemophilus parasuis SH0165 hypothetical protein YP_002476641.1 2230025 D 557723 CDS YP_002476642.1 219872267 7277230 2230669..2231322 1 NC_011852.1 COG:L;COG3676; IS1016C2 transposase, family IS1595 2231322 7277230 HAPS_2264 Haemophilus parasuis SH0165 IS1016C2 transposase, family IS1595 YP_002476642.1 2230669 D 557723 CDS YP_002476643.1 219872268 7277231 2231543..2232079 1 NC_011852.1 affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 2232079 proQ 7277231 proQ Haemophilus parasuis SH0165 putative solute/DNA competence effector YP_002476643.1 2231543 D 557723 CDS YP_002476644.1 219872269 7277232 2232099..2234105 1 NC_011852.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2234105 prc 7277232 prc Haemophilus parasuis SH0165 carboxy-terminal protease YP_002476644.1 2232099 D 557723 CDS YP_002476645.1 219872270 7277233 2234191..2235741 1 NC_011852.1 COG:S;COG2989; hypothetical protein 2235741 7277233 HAPS_2267 Haemophilus parasuis SH0165 hypothetical protein YP_002476645.1 2234191 D 557723 CDS YP_002476646.1 219872271 7277234 2235886..2236443 1 NC_011852.1 COG:S;COG3108; hypothetical protein 2236443 7277234 HAPS_2268 Haemophilus parasuis SH0165 hypothetical protein YP_002476646.1 2235886 D 557723 CDS YP_002476647.1 219872272 7277235 2236457..2237086 1 NC_011852.1 COG:R;COG0491; glyoxalase II family protein 2237086 7277235 HAPS_2269 Haemophilus parasuis SH0165 glyoxalase II family protein YP_002476647.1 2236457 D 557723 CDS YP_002476648.1 219872273 7277236 2237091..2237837 1 NC_011852.1 COG:M;COG2853; VacJ lipoprotein 2237837 vacJ 7277236 vacJ Haemophilus parasuis SH0165 VacJ lipoprotein YP_002476648.1 2237091 D 557723 CDS YP_002476649.1 219872274 7277237 2237946..2238380 1 NC_011852.1 COG:KT;COG1974; SOS-response transcriptional repressor 2238380 impA 7277237 impA Haemophilus parasuis SH0165 SOS-response transcriptional repressor YP_002476649.1 2237946 D 557723 CDS YP_002476650.1 219872275 7277239 complement(2238939..2240045) 1 NC_011852.1 catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase 2240045 metB 7277239 metB Haemophilus parasuis SH0165 cystathionine gamma-synthase YP_002476650.1 2238939 R 557723 CDS YP_002476651.1 219872276 7277240 complement(2240093..2240905) 1 NC_011852.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 2240905 dapB 7277240 dapB Haemophilus parasuis SH0165 dihydrodipicolinate reductase YP_002476651.1 2240093 R 557723 CDS YP_002476652.1 219872277 7277241 complement(2241040..2241921) 1 NC_011852.1 COG:E;COG0685; 5,10-methylenetetrahydrofolate reductase 2241921 metF 7277241 metF Haemophilus parasuis SH0165 5,10-methylenetetrahydrofolate reductase YP_002476652.1 2241040 R 557723 CDS YP_002476653.1 219872278 7277242 2242233..2243480 1 NC_011852.1 COG:C;COG0538; isocitrate dehydrogenase (NADP(+)) 2243480 icd 7277242 icd Haemophilus parasuis SH0165 isocitrate dehydrogenase (NADP(+)) YP_002476653.1 2242233 D 557723 CDS YP_002476654.1 219872279 7277243 2243632..2246235 1 NC_011852.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 2246235 acnB 7277243 acnB Haemophilus parasuis SH0165 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002476654.1 2243632 D 557723 CDS YP_002476655.1 219872280 7277244 2246271..2247551 1 NC_011852.1 COG:C;COG0372; type II citrate synthase 2247551 gltA 7277244 gltA Haemophilus parasuis SH0165 type II citrate synthase YP_002476655.1 2246271 D 557723 CDS YP_002476656.1 219872281 7277245 complement(2247630..2248217) 1 NC_011852.1 COG:F;COG0563; adenylate kinase 2248217 adk 7277245 adk Haemophilus parasuis SH0165 adenylate kinase YP_002476656.1 2247630 R 557723 CDS YP_002476657.1 219872282 7277246 complement(2248384..2249742) 1 NC_011852.1 COG:R;COG0733; putative Na+-dependent transporters of the SNF family 2249742 7277246 HAPS_2280 Haemophilus parasuis SH0165 putative Na+-dependent transporters of the SNF family YP_002476657.1 2248384 R 557723 CDS YP_002476658.1 219872283 7277247 complement(2249771..2250589) 1 NC_011852.1 COG:L;COG0338; DNA adenine methylase Dam 2250589 dam 7277247 dam Haemophilus parasuis SH0165 DNA adenine methylase Dam YP_002476658.1 2249771 R 557723 CDS YP_002476659.1 219872284 7277248 complement(2250599..2251576) 1 NC_011852.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 2251576 aroB 7277248 aroB Haemophilus parasuis SH0165 3-dehydroquinate synthase YP_002476659.1 2250599 R 557723 CDS YP_002476660.1 219872285 7277249 complement(2251702..2252223) 1 NC_011852.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 2252223 aroK 7277249 aroK Haemophilus parasuis SH0165 shikimate kinase YP_002476660.1 2251702 R 557723 CDS YP_002476661.1 219872286 7277250 complement(2252453..2255008) 1 NC_011852.1 COG:M;COG5009; membrane carboxypeptidase/penicillin-binding protein 1A 2255008 mrcA 7277250 mrcA Haemophilus parasuis SH0165 membrane carboxypeptidase/penicillin-binding protein 1A YP_002476661.1 2252453 R 557723 CDS YP_002476662.1 219872287 7277251 2255162..2255839 1 NC_011852.1 competence protein A 2255839 comA 7277251 comA Haemophilus parasuis SH0165 competence protein A YP_002476662.1 2255162 D 557723 CDS YP_002476663.1 219872288 7277252 2255815..2256336 1 NC_011852.1 hypothetical protein 2256336 7277252 HAPS_2286 Haemophilus parasuis SH0165 hypothetical protein YP_002476663.1 2255815 D 557723 CDS YP_002476664.1 219872289 7277253 2256333..2256863 1 NC_011852.1 chromosome segregation ATPase 2256863 7277253 HAPS_2287 Haemophilus parasuis SH0165 chromosome segregation ATPase YP_002476664.1 2256333 D 557723 CDS YP_002476665.1 219872290 7277254 2256863..2257249 1 NC_011852.1 hypothetical protein 2257249 7277254 HAPS_2288 Haemophilus parasuis SH0165 hypothetical protein YP_002476665.1 2256863 D 557723 CDS YP_002476666.1 219872291 7277255 2257259..2258521 1 NC_011852.1 COG:U;COG4796; competence protein E/type II secretory pathway, component HofQ 2258521 comE 7277255 comE Haemophilus parasuis SH0165 competence protein E/type II secretory pathway, component HofQ YP_002476666.1 2257259 D 557723 CDS YP_002476667.1 219872292 7277256 2258600..2259013 1 NC_011852.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 2259013 nusB 7277256 nusB Haemophilus parasuis SH0165 transcription antitermination protein NusB YP_002476667.1 2258600 D 557723 CDS YP_002476668.1 219872293 7277257 2259022..2259990 1 NC_011852.1 COG:H;COG0611; thiamin-monophosphate kinase 2259990 thiL 7277257 thiL Haemophilus parasuis SH0165 thiamin-monophosphate kinase YP_002476668.1 2259022 D 557723 CDS YP_002476669.1 219872294 7277258 2260107..2260463 1 NC_011852.1 COG:I;COG1267; phosphatidylglycerophosphatase A 2260463 pgpA 7277258 pgpA Haemophilus parasuis SH0165 phosphatidylglycerophosphatase A YP_002476669.1 2260107 D 557723 CDS YP_002476670.1 219872295 7277259 2260465..2261094 1 NC_011852.1 COG:E;COG1280; threonine efflux protein, RhtB family homoserine/threonine resistance transporter 2261094 rhtB 7277259 rhtB Haemophilus parasuis SH0165 threonine efflux protein, RhtB family homoserine/threonine resistance transporter YP_002476670.1 2260465 D 557723 CDS YP_002476671.1 219872296 7277260 2261391..2261705 1 NC_011852.1 COG:OC;COG0526; thioredoxin 2261705 trxA 7277260 trxA Haemophilus parasuis SH0165 thioredoxin YP_002476671.1 2261391 D 557723 CDS YP_002476672.1 219872297 7277262 complement(2263089..2263508) 1 NC_011852.1 COG:Q;COG2050; hypothetical protein 2263508 7277262 HAPS_2296 Haemophilus parasuis SH0165 hypothetical protein YP_002476672.1 2263089 R 557723 CDS YP_002476673.1 219872298 7277263 complement(2263841..2266933) 1 NC_011852.1 COG:C;COG0277; FAD/FMN-containing dehydrogenase 2266933 7277263 HAPS_2297 Haemophilus parasuis SH0165 FAD/FMN-containing dehydrogenase YP_002476673.1 2263841 R 557723 CDS YP_002476674.1 219872299 7277264 2267336..2268451 1 NC_011852.1 COG:M;COG2885; outer membrane protein P5 , heat-modifiable outer membrane protein 2268451 ompP5 7277264 ompP5 Haemophilus parasuis SH0165 outer membrane protein P5 , heat-modifiable outer membrane protein YP_002476674.1 2267336 D 557723 CDS YP_002476675.1 219872300 7277265 complement(2268533..2268928) 1 NC_011852.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2268928 msrB 7277265 msrB Haemophilus parasuis SH0165 methionine sulfoxide reductase B YP_002476675.1 2268533 R 557723 CDS