-- dump date 20120504_150129 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_003056844.1 254778739 8209096 complement(105..521) 1 NC_012973.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 521 nusB 8209096 nusB Helicobacter pylori B38 transcription antitermination protein NusB YP_003056844.1 105 R 592205 CDS YP_003056845.1 254778740 8208824 complement(523..993) 1 NC_012973.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 993 ribH 8208824 ribH Helicobacter pylori B38 6,7-dimethyl-8-ribityllumazine synthase YP_003056845.1 523 R 592205 CDS YP_003056846.1 254778741 8208921 complement(1003..1833) 1 NC_012973.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1833 kdsA 8208921 kdsA Helicobacter pylori B38 2-dehydro-3-deoxyphosphooctonate aldolase YP_003056846.1 1003 R 592205 CDS YP_003056847.1 254778742 8208722 complement(1820..2485) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15866214, 3049588, 9761692; Product type e : enzyme; Beta-carbonic anhydrase 2485 icfA 8208722 icfA Helicobacter pylori B38 Beta-carbonic anhydrase YP_003056847.1 1820 R 592205 CDS YP_003056848.1 254778743 8208707 2605..3288 1 NC_012973.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 3288 pyrF 8208707 pyrF Helicobacter pylori B38 orotidine 5'-phosphate decarboxylase YP_003056848.1 2605 D 592205 CDS YP_003056849.1 254778744 8208896 3289..4119 1 NC_012973.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 4119 panC 8208896 panC Helicobacter pylori B38 pantoate--beta-alanine ligase YP_003056849.1 3289 D 592205 CDS YP_003056850.1 254778745 8208349 complement(5118..7130) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 18192681, 16322107, 16220040, 16173498, 15918181, 12454856, 11211867; Product type m : membrane component; outer membrane protein HopZ 7130 hopZ 8208349 hopZ Helicobacter pylori B38 outer membrane protein HopZ YP_003056850.1 5118 R 592205 CDS YP_003056851.1 254778746 8208665 complement(7478..9118) 1 NC_012973.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 9118 groEL 8208665 groEL Helicobacter pylori B38 chaperonin GroEL YP_003056851.1 7478 R 592205 CDS YP_003056852.1 254778747 8208604 complement(9144..9500) 1 NC_012973.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 9500 groES 8208604 groES Helicobacter pylori B38 co-chaperonin GroES YP_003056852.1 9144 R 592205 CDS YP_003056853.1 254778748 8208605 9787..11466 1 NC_012973.1 synthesizes RNA primers at the replication forks; DNA primase 11466 dnaG 8208605 dnaG Helicobacter pylori B38 DNA primase YP_003056853.1 9787 D 592205 CDS YP_003056854.1 254778749 8208465 11463..12515 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 12515 8208465 HELPY_0011 Helicobacter pylori B38 hypothetical protein YP_003056854.1 11463 D 592205 CDS YP_003056855.1 254778750 8207526 12605..13432 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 13432 8207526 HELPY_0012 Helicobacter pylori B38 hypothetical protein YP_003056855.1 12605 D 592205 CDS YP_003056856.1 254778751 8207527 13578..13859 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 13859 8207527 HELPY_0013 Helicobacter pylori B38 hypothetical protein YP_003056856.1 13578 D 592205 CDS YP_003056857.1 254778752 8207528 13859..14122 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 14122 8207528 HELPY_0014 Helicobacter pylori B38 hypothetical protein YP_003056857.1 13859 D 592205 CDS YP_003056858.1 254778753 8207529 14124..16487 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16428391, 15133060, 12868652, 12668646, 11489125, 10383764, 10066547; Product type t : transporter; ATPase/DNA transfer protein 16487 comB4 8207529 comB4 Helicobacter pylori B38 ATPase/DNA transfer protein YP_003056858.1 14124 D 592205 CDS YP_003056859.1 254778754 8208323 16670..18121 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 18121 8208323 HELPY_0016 Helicobacter pylori B38 hypothetical protein YP_003056859.1 16670 D 592205 CDS YP_003056860.1 254778755 8207530 18229..19194 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15664919, 15205568, 15130117, 14631875, 8809743, 8169224, 8169223; Product type r : regulator; Chemotaxis protein (Che V) 19194 cheV1 8207530 cheV1 Helicobacter pylori B38 Chemotaxis protein (Che V) YP_003056860.1 18229 D 592205 CDS YP_003056861.1 254778756 8208420 19191..20408 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16009566, 1955861, 16237027; Product type e : enzyme; Carboxynorspermidine decarboxylase 20408 nspC 8208420 nspC Helicobacter pylori B38 Carboxynorspermidine decarboxylase YP_003056861.1 19191 D 592205 CDS YP_003056862.1 254778757 8208807 complement(20418..20990) 1 NC_012973.1 inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase 20990 8208807 HELPY_0019 Helicobacter pylori B38 lipid A 1-phosphatase YP_003056862.1 20418 R 592205 CDS YP_003056863.1 254778758 8207531 complement(21001..22566) 1 NC_012973.1 attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase 22566 8207531 HELPY_0020 Helicobacter pylori B38 lipid A phosphoethanolamine transferase YP_003056863.1 21001 R 592205 CDS YP_003056864.1 254778759 8207532 complement(22598..22738) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 22738 8207532 HELPY_0021 Helicobacter pylori B38 hypothetical protein YP_003056864.1 22598 R 592205 CDS YP_003056865.1 254778760 8207533 complement(23206..25338) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7534278, 7559328, 16322107, 16173498, 15918181, 12454856, 7534278; Product type m : membrane component; outer membrane protein HopD 25338 hopD 8207533 hopD Helicobacter pylori B38 outer membrane protein HopD YP_003056865.1 23206 R 592205 CDS YP_003056866.1 254778761 8208651 complement(25869..27149) 1 NC_012973.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 27149 gltA 8208651 gltA Helicobacter pylori B38 type II citrate synthase YP_003056866.1 25869 R 592205 CDS YP_003056867.1 254778762 8208589 27350..28627 1 NC_012973.1 [NADP]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091606, 2204109, 2682654, 8759844; Product type e : enzyme; Isocitrate dehydrogenase 28627 icd 8208589 icd Helicobacter pylori B38 Isocitrate dehydrogenase YP_003056867.1 27350 D 592205 CDS YP_003056868.1 254778763 8208706 28694..29221 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 29221 8208706 HELPY_0026 Helicobacter pylori B38 hypothetical protein YP_003056868.1 28694 D 592205 CDS YP_003056869.1 254778764 8207534 complement(29198..29851) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 374977, 9214291, 7669755, 10089457, 99081548, 9865950; Product type e : enzyme; dethiobiotin synthetase 29851 bioD 8207534 bioD Helicobacter pylori B38 dethiobiotin synthetase YP_003056869.1 29198 R 592205 CDS YP_003056870.1 254778765 8208407 complement(29855..31567) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 31567 8208407 HELPY_0028 Helicobacter pylori B38 hypothetical protein YP_003056870.1 29855 R 592205 CDS YP_003056871.1 254778766 8207535 31676..32089 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16159758, 12732303; Product type pr : regulator; universal stress global response regulator UspA 32089 8207535 HELPY_0029 Helicobacter pylori B38 universal stress global response regulator UspA YP_003056871.1 31676 D 592205 CDS YP_003056872.1 254778767 8207536 32104..32379 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11931773, 12426582; Product type r : regulator; ATP-dependent Clp protease adaptor protein ClpS 32379 clpS 8207536 clpS Helicobacter pylori B38 ATP-dependent Clp protease adaptor protein ClpS YP_003056872.1 32104 D 592205 CDS YP_003056873.1 254778768 8208428 32379..34604 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8885261, 3049606, 10555973, 10485712; Product type e : enzyme; ATP-dependent Clp protease ATP-binding subunit ClpA 34604 clpA 8208428 clpA Helicobacter pylori B38 ATP-dependent Clp protease ATP-binding subunit ClpA YP_003056873.1 32379 D 592205 CDS YP_003056874.1 254778769 8208425 34606..34947 1 NC_012973.1 (Aspartate alpha-decarboxylase) [Contains: Aspartate 1-decarboxylase beta chain; Aspartate 1-decarboxylase alpha chain]; Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 34947 panD 8208425 panD Helicobacter pylori B38 aspartate alpha-decarboxylase YP_003056874.1 34606 D 592205 CDS YP_003056875.1 254778770 8208838 34950..35252 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 35252 8208838 HELPY_0033 Helicobacter pylori B38 hypothetical protein YP_003056875.1 34950 D 592205 CDS YP_003056876.1 254778771 8207537 35249..36256 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 36256 8207537 HELPY_0034 Helicobacter pylori B38 hypothetical protein YP_003056876.1 35249 D 592205 CDS YP_003056877.1 254778772 8207538 36264..37319 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; Product type pm : membrane component; hypothetical protein 37319 8207538 HELPY_0035 Helicobacter pylori B38 hypothetical protein YP_003056877.1 36264 D 592205 CDS YP_003056878.1 254778773 8207539 37445..38188 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12868652, 11489125, 11371528, 9663688; Product type t : transporter; DNA transformation competence protein ComB8 38188 comB8 8207539 comB8 Helicobacter pylori B38 DNA transformation competence protein ComB8 YP_003056878.1 37445 D 592205 CDS YP_003056879.1 254778774 8208434 38188..39177 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12868652, 11489125, 11371528, 10920394, 9663688; Product type f : factor; DNA transformation competence protein ComB9 39177 comB9 8208434 comB9 Helicobacter pylori B38 DNA transformation competence protein ComB9 YP_003056879.1 38188 D 592205 CDS YP_003056880.1 254778775 8208435 39170..40300 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12868652, 11489125, 11371528, 10920394, 9663688, 8763954; Product type f : factor; DNA transformation competence protein ComB10 40300 comB10 8208435 comB10 Helicobacter pylori B38 DNA transformation competence protein ComB10 YP_003056880.1 39170 D 592205 CDS YP_003056881.1 254778776 8208432 40371..41783 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17547009, 16769546, 16713544, 15126474, 3089876; Product type e : enzyme; Alginate biosynthesis protein AlgA 41783 manC 8208432 manC Helicobacter pylori B38 Alginate biosynthesis protein AlgA YP_003056881.1 40371 D 592205 CDS YP_003056882.1 254778777 8208749 41824..42969 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14739333, 11856318, 11737200, 11444851, 9257704, 10673432, 8759852; Product type e : enzyme; GDP-mannose 4,6-dehydratase 42969 gmd 8208749 gmd Helicobacter pylori B38 GDP-mannose 4,6-dehydratase YP_003056882.1 41824 D 592205 CDS YP_003056883.1 254778778 8208596 42962..43894 1 NC_012973.1 : GDP-4-dehydro-6-deoxy-D-mannose epimerase; GDP-4-dehydro-6-L-deoxygalactose reductase; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9786182, 9473059, 9862812, 8759852; Product type e : enzyme; Bifunctional GDP-fucose synthetase 43894 fcl 8208596 fcl Helicobacter pylori B38 Bifunctional GDP-fucose synthetase YP_003056883.1 42962 D 592205 CDS YP_003056884.1 254778779 8208500 complement(44210..45208) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 16412426, 15291820, 1482271, 1849603; Product type f : factor; Hydrogenase expression/formation protein 45208 hypE 8208500 hypE Helicobacter pylori B38 Hydrogenase expression/formation protein YP_003056884.1 44210 R 592205 CDS YP_003056885.1 254778780 8208704 complement(45220..47493) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 15491154, 11123699, 8661925; Product type r : regulator; Hydrogenase maturation protein HypF 47493 hypF 8208704 hypF Helicobacter pylori B38 Hydrogenase maturation protein HypF YP_003056885.1 45220 R 592205 CDS YP_003056886.1 254778781 8208705 complement(47469..48461) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310, 10954588; Product type pe : enzyme; non-functional type II restriction endonuclease 48461 8208705 HELPY_0044 Helicobacter pylori B38 non-functional type II restriction endonuclease YP_003056886.1 47469 R 592205 CDS YP_003056887.1 254778782 8207540 complement(48513..49211) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11226310, 10954588, 15297930, 12657791, 12486066, 12426350, 12355374; Product type e : enzyme; type II adenine methyltransferase 49211 hpy99VM 8207540 hpy99VM Helicobacter pylori B38 type II adenine methyltransferase YP_003056887.1 48513 R 592205 CDS YP_003056888.1 254778783 8207542 complement(50353..51843) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16368996; Product type t : transporter; Symporter, SSS family (Proline Permease); membrane protein 51843 8207542 HELPY_0048 Helicobacter pylori B38 Symporter, SSS family (Proline Permease); membrane protein YP_003056888.1 50353 R 592205 CDS YP_003056889.1 254778784 8207543 complement(51870..55427) 1 NC_012973.1 (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16452403, 15966737, 15449943, 7966312; Product type t : transporter; bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase 55427 putA 8207543 putA Helicobacter pylori B38 bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase YP_003056889.1 51870 R 592205 CDS YP_003056890.1 254778785 8208889 55756..55965 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 55965 8208889 HELPY_0050 Helicobacter pylori B38 hypothetical protein YP_003056890.1 55756 D 592205 CDS YP_003056891.1 254778786 8207544 56288..57265 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 57265 8207544 HELPY_0051 Helicobacter pylori B38 hypothetical protein YP_003056891.1 56288 D 592205 CDS YP_003056892.1 254778787 8207545 57266..58111 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 58111 8207545 HELPY_0052 Helicobacter pylori B38 hypothetical protein YP_003056892.1 57266 D 592205 CDS YP_003056893.1 254778788 8207548 60534..61103 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 61103 8207548 HELPY_0055 Helicobacter pylori B38 hypothetical protein YP_003056893.1 60534 D 592205 CDS YP_003056894.1 254778789 8207549 61119..61379 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 61379 8207549 HELPY_0056 Helicobacter pylori B38 hypothetical protein YP_003056894.1 61119 D 592205 CDS YP_003056895.1 254778790 8207550 61390..63099 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 63099 8207550 HELPY_0057 Helicobacter pylori B38 hypothetical protein YP_003056895.1 61390 D 592205 CDS YP_003056896.1 254778791 8207551 63132..63494 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 63494 8207551 HELPY_0058 Helicobacter pylori B38 hypothetical protein YP_003056896.1 63132 D 592205 CDS YP_003056897.1 254778792 8207552 63496..63843 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 63843 8207552 HELPY_0059 Helicobacter pylori B38 hypothetical protein YP_003056897.1 63496 D 592205 CDS YP_003056898.1 254778793 8207556 complement(66337..67134) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type f : factor; urease accessory protein UreH 67134 ureH 8207556 ureH Helicobacter pylori B38 urease accessory protein UreH YP_003056898.1 66337 R 592205 CDS YP_003056899.1 254778794 8209081 complement(67134..67733) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type e : enzyme; urease accessory protein UreG 67733 ureG 8209081 ureG Helicobacter pylori B38 urease accessory protein UreG YP_003056899.1 67134 R 592205 CDS YP_003056900.1 254778795 8209080 complement(67762..68532) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type e : enzyme; urease accessory protein UreF 68532 ureF 8209080 ureF Helicobacter pylori B38 urease accessory protein UreF YP_003056900.1 67762 R 592205 CDS YP_003056901.1 254778796 8209079 complement(68556..69068) 1 NC_012973.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 69068 ureE 8209079 ureE Helicobacter pylori B38 urease accessory protein UreE YP_003056901.1 68556 R 592205 CDS YP_003056902.1 254778797 8209078 complement(69070..69657) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type e : enzyme; urease accessory protein UreI 69657 ureI 8209078 ureI Helicobacter pylori B38 urease accessory protein UreI YP_003056902.1 69070 R 592205 CDS YP_003056903.1 254778798 8209082 complement(69850..71559) 1 NC_012973.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta 71559 ureB 8209082 ureB Helicobacter pylori B38 urease subunit beta YP_003056903.1 69850 R 592205 CDS YP_003056904.1 254778799 8209076 complement(71563..72279) 1 NC_012973.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha 72279 ureA 8209076 ureA Helicobacter pylori B38 urease subunit alpha YP_003056904.1 71563 R 592205 CDS YP_003056905.1 254778800 8208348 complement(72625..73098) 1 NC_012973.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 73098 lspA 8208348 lspA Helicobacter pylori B38 lipoprotein signal peptidase YP_003056905.1 72625 R 592205 CDS YP_003056906.1 254778801 8208743 complement(73092..74429) 1 NC_012973.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 74429 glmM 8208743 glmM Helicobacter pylori B38 phosphoglucosamine mutase YP_003056906.1 73092 R 592205 CDS YP_003056907.1 254778802 8209077 74519..74788 1 NC_012973.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 74788 rpsT 8209077 rpsT Helicobacter pylori B38 30S ribosomal protein S20 YP_003056907.1 74519 D 592205 CDS YP_003056908.1 254778803 8208994 74916..75974 1 NC_012973.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 75974 prfA 8208994 prfA Helicobacter pylori B38 peptide chain release factor 1 YP_003056908.1 74916 D 592205 CDS YP_003056909.1 254778804 8207558 78302..80065 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 80065 8207558 HELPY_0077 Helicobacter pylori B38 hypothetical protein YP_003056909.1 78302 D 592205 CDS YP_003056910.1 254778805 8207559 complement(80455..82476) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17517875, 16547053, 12228322, 96405614; Product type r : regulator; methyl-accepting chemotaxis protein 82476 tlpC 8207559 tlpC Helicobacter pylori B38 methyl-accepting chemotaxis protein YP_003056910.1 80455 R 592205 CDS YP_003056911.1 254778806 8209041 complement(82617..83006) 1 NC_012973.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 83006 rpsI 8209041 rpsI Helicobacter pylori B38 30S ribosomal protein S9 YP_003056911.1 82617 R 592205 CDS YP_003056912.1 254778807 8208983 complement(83003..83428) 1 NC_012973.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 83428 rplM 8208983 rplM Helicobacter pylori B38 50S ribosomal protein L13 YP_003056912.1 83003 R 592205 CDS YP_003056913.1 254778808 8208949 complement(83738..83926) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 83926 8208949 HELPY_0082 Helicobacter pylori B38 hypothetical protein YP_003056913.1 83738 R 592205 CDS YP_003056914.1 254778809 8207560 complement(83932..85284) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10809701, 10809701, 16332763, 12480887; Product type e : enzyme; malate:quinone oxidoreductase 85284 mqo 8207560 mqo Helicobacter pylori B38 malate:quinone oxidoreductase YP_003056914.1 83932 R 592205 CDS YP_003056915.1 254778810 8208777 complement(85338..86711) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 86711 8208777 HELPY_0084 Helicobacter pylori B38 hypothetical protein YP_003056915.1 85338 R 592205 CDS YP_003056916.1 254778811 8207561 complement(86732..88771) 1 NC_012973.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 88771 rpoD 8207561 rpoD Helicobacter pylori B38 RNA polymerase sigma factor RpoD YP_003056916.1 86732 R 592205 CDS YP_003056917.1 254778812 8208972 complement(89051..89746) 1 NC_012973.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 89746 8208972 HELPY_0086 Helicobacter pylori B38 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_003056917.1 89051 R 592205 CDS YP_003056918.1 254778813 8207562 complement(89757..90686) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16699188, 16112872, 15952903, 14586097, 12842120, 12575934; Product type e : enzyme; Malonyl CoA-acyl carrier protein transacylase (MCT) 90686 fabD 8207562 fabD Helicobacter pylori B38 Malonyl CoA-acyl carrier protein transacylase (MCT) YP_003056918.1 89757 R 592205 CDS YP_003056919.1 254778814 8207564 91938..92771 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12486066, 11226310; Product type e : enzyme; type II adenine methyltransferase 92771 hpyAIIIM 8207564 hpyAIIIM Helicobacter pylori B38 type II adenine methyltransferase YP_003056919.1 91938 D 592205 CDS YP_003056920.1 254778815 8208680 complement(92792..93694) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16477004, 16720729; Product type e : enzyme; Alpha-1,2-fucosyltransferase 93694 futC 8208680 futC Helicobacter pylori B38 Alpha-1,2-fucosyltransferase YP_003056920.1 92792 R 592205 CDS YP_003056921.1 254778816 8208573 complement(93794..94324) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 94324 8208573 HELPY_0092 Helicobacter pylori B38 hypothetical protein YP_003056921.1 93794 R 592205 CDS YP_003056922.1 254778817 8207565 94397..95341 1 NC_012973.1 Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 95341 8207565 HELPY_0093 Helicobacter pylori B38 2-hydroxyacid dehydrogenase YP_003056922.1 94397 D 592205 CDS YP_003056923.1 254778818 8207566 complement(95555..96268) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 96268 8207566 HELPY_0094 Helicobacter pylori B38 hypothetical protein YP_003056923.1 95555 R 592205 CDS YP_003056924.1 254778819 8207567 complement(96373..97827) 1 NC_012973.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 97827 thrC 8207567 thrC Helicobacter pylori B38 threonine synthase YP_003056924.1 96373 R 592205 CDS YP_003056925.1 254778820 8209034 98030..100057 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16529985, 16369945, 10692349; Product type pr : regulator; methyl-accepting chemotaxis protein 100057 8209034 HELPY_0097 Helicobacter pylori B38 methyl-accepting chemotaxis protein YP_003056925.1 98030 D 592205 CDS YP_003056926.1 254778821 8207568 100057..101163 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 101163 8207568 HELPY_0098 Helicobacter pylori B38 hypothetical protein YP_003056926.1 100057 D 592205 CDS YP_003056927.1 254778822 8207569 101376..102137 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein 102137 8207569 HELPY_0099 Helicobacter pylori B38 outer membrane protein YP_003056927.1 101376 D 592205 CDS YP_003056928.1 254778823 8207570 complement(102134..102901) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl transferase family protein 102901 8207570 HELPY_0100 Helicobacter pylori B38 glycosyl transferase family protein YP_003056928.1 102134 R 592205 CDS YP_003056929.1 254778824 8207571 complement(102933..104630) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15731083, 16547053; Product type m : membrane component; methyl-accepting chemotaxis protein tlpB 104630 tlpB 8207571 tlpB Helicobacter pylori B38 methyl-accepting chemotaxis protein tlpB YP_003056929.1 102933 R 592205 CDS YP_003056930.1 254778825 8209040 complement(104833..106578) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11160814, 2172762, 6251162; Product type e : enzyme; 2,3-cyclic-nucleotide 2'phosphodiesterase 106578 cpdB 8209040 cpdB Helicobacter pylori B38 2,3-cyclic-nucleotide 2'phosphodiesterase YP_003056930.1 104833 R 592205 CDS YP_003056931.1 254778826 8208441 complement(106722..107180) 1 NC_012973.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 107180 luxS 8208441 luxS Helicobacter pylori B38 S-ribosylhomocysteinase YP_003056931.1 106722 R 592205 CDS YP_003056932.1 254778827 8208744 complement(107218..108360) 1 NC_012973.1 catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase 108360 metB 8208744 metB Helicobacter pylori B38 cystathionine gamma-synthase YP_003056932.1 107218 R 592205 CDS YP_003056933.1 254778828 8208752 complement(108385..109302) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15952768, 14996787, 9034314; Product type e : enzyme; cysteine synthase 109302 cysK 8208752 cysK Helicobacter pylori B38 cysteine synthase YP_003056933.1 108385 R 592205 CDS YP_003056934.1 254778829 8207573 complement(110242..112104) 1 NC_012973.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 112104 dnaK 8207573 dnaK Helicobacter pylori B38 molecular chaperone DnaK YP_003056934.1 110242 R 592205 CDS YP_003056935.1 254778830 8208468 complement(112135..112710) 1 NC_012973.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 112710 grpE 8208468 grpE Helicobacter pylori B38 heat shock protein GrpE YP_003056935.1 112135 R 592205 CDS YP_003056936.1 254778831 8208606 complement(112710..113480) 1 NC_012973.1 Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor 113480 hrcA 8208606 hrcA Helicobacter pylori B38 heat-inducible transcription repressor YP_003056936.1 112710 R 592205 CDS YP_003056937.1 254778832 8208685 113752..114390 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511238, 15126455, 10821675, 8676381; Product type pe : enzyme; hypothetical protein 114390 8208685 HELPY_0112 Helicobacter pylori B38 hypothetical protein YP_003056937.1 113752 D 592205 CDS YP_003056938.1 254778833 8207574 114411..114707 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 114707 8207574 HELPY_0113 Helicobacter pylori B38 hypothetical protein YP_003056938.1 114411 D 592205 CDS YP_003056939.1 254778834 8207575 complement(114717..116600) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 116600 8207575 HELPY_0114 Helicobacter pylori B38 hypothetical protein YP_003056939.1 114717 R 592205 CDS YP_003056940.1 254778835 8207576 complement(116650..118194) 1 NC_012973.1 FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B 118194 flaB 8207576 flaB Helicobacter pylori B38 flagellin B YP_003056940.1 116650 R 592205 CDS YP_003056941.1 254778836 8208513 118360..120570 1 NC_012973.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 120570 topA 8208513 topA Helicobacter pylori B38 DNA topoisomerase I YP_003056941.1 118360 D 592205 CDS YP_003056942.1 254778837 8209046 120563..121489 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 121489 8209046 HELPY_0117 Helicobacter pylori B38 hypothetical protein YP_003056942.1 120563 D 592205 CDS YP_003056943.1 254778838 8207579 complement(122932..125364) 1 NC_012973.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 125364 pps 8207579 pps Helicobacter pylori B38 phosphoenolpyruvate synthase YP_003056943.1 122932 R 592205 CDS YP_003056944.1 254778839 8208872 125549..125680 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 125680 8208872 HELPY_0121 Helicobacter pylori B38 hypothetical protein YP_003056944.1 125549 D 592205 CDS YP_003056945.1 254778840 8207580 125721..127559 1 NC_012973.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 127559 thrS 8207580 thrS Helicobacter pylori B38 threonyl-tRNA synthetase YP_003056945.1 125721 D 592205 CDS YP_003056946.1 254778841 8209035 127556..128167 1 NC_012973.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 128167 infC 8209035 infC Helicobacter pylori B38 translation initiation factor IF-3 YP_003056946.1 127556 D 592205 CDS YP_003056947.1 254778842 8208714 128148..128342 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12166643; Product type s : structure; 50S ribosomal protein L35 128342 rpmI 8208714 rpmI Helicobacter pylori B38 50S ribosomal protein L35 YP_003056947.1 128148 D 592205 CDS YP_003056948.1 254778843 8208969 128436..128786 1 NC_012973.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 128786 rplT 8208969 rplT Helicobacter pylori B38 50S ribosomal protein L20 YP_003056948.1 128436 D 592205 CDS YP_003056949.1 254778844 8208956 128986..129846 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10225855; Product type m : membrane component; outer membrane protein HorB 129846 horB 8208956 horB Helicobacter pylori B38 outer membrane protein HorB YP_003056949.1 128986 D 592205 CDS YP_003056950.1 254778845 8208666 129889..130023 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 130023 8208666 HELPY_0127 Helicobacter pylori B38 hypothetical protein YP_003056950.1 129889 D 592205 CDS YP_003056951.1 254778846 8207581 130196..130627 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 130627 8207581 HELPY_0128 Helicobacter pylori B38 hypothetical protein YP_003056951.1 130196 D 592205 CDS YP_003056952.1 254778847 8207582 131040..131900 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 131900 8207582 HELPY_0130 Helicobacter pylori B38 hypothetical protein YP_003056952.1 131040 D 592205 CDS YP_003056953.1 254778848 8207583 complement(132534..133901) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2013569, 2504697; Product type e : enzyme; L-serine dehydratase 133901 sdaA 8207583 sdaA Helicobacter pylori B38 L-serine dehydratase YP_003056953.1 132534 R 592205 CDS YP_003056954.1 254778849 8209001 complement(133901..135142) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16285745, 15629915, 15743941, 12558182, 8026499; Product type t : transporter; Aminoacid transport protein, HAAAP family; membrane protein 135142 sdaC 8209001 sdaC Helicobacter pylori B38 Aminoacid transport protein, HAAAP family; membrane protein YP_003056954.1 133901 R 592205 CDS YP_003056955.1 254778850 8209002 135323..136672 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8760910, 11506923; Product type e : enzyme; Tyrosine-regulated 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHP synthase) 136672 aroF 8209002 aroF Helicobacter pylori B38 Tyrosine-regulated 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHP synthase) YP_003056955.1 135323 D 592205 CDS YP_003056956.1 254778851 8208384 136961..137095 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 137095 8208384 HELPY_0136 Helicobacter pylori B38 hypothetical protein YP_003056956.1 136961 D 592205 CDS YP_003056957.1 254778852 8207584 complement(137327..137785) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15618175, 10998352, 10644761; Product type e : enzyme; Bacterioferritin comigratory protein 137785 bcp 8207584 bcp Helicobacter pylori B38 Bacterioferritin comigratory protein YP_003056957.1 137327 R 592205 CDS YP_003056958.1 254778853 8208403 complement(137795..138430) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 138430 8208403 HELPY_0138 Helicobacter pylori B38 hypothetical protein YP_003056958.1 137795 R 592205 CDS YP_003056959.1 254778854 8207585 complement(138423..139868) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; iron-sulfur cluster binding protein 139868 8207585 HELPY_0139 Helicobacter pylori B38 iron-sulfur cluster binding protein YP_003056959.1 138423 R 592205 CDS YP_003056960.1 254778855 8207586 complement(139897..140625) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 140625 8207586 HELPY_0140 Helicobacter pylori B38 hypothetical protein YP_003056960.1 139897 R 592205 CDS YP_003056961.1 254778856 8207587 140850..142499 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8407843, 11785976; Product type t : transporter; L-lactate permease, LctP family; membrane protein 142499 8207587 HELPY_0142 Helicobacter pylori B38 L-lactate permease, LctP family; membrane protein YP_003056961.1 140850 D 592205 CDS YP_003056962.1 254778857 8207588 142549..144204 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8407843, 11785976; Product type t : transporter; L-lactate permease, LctP family; membrane protein 144204 8207588 HELPY_0143 Helicobacter pylori B38 L-lactate permease, LctP family; membrane protein YP_003056962.1 142549 D 592205 CDS YP_003056963.1 254778858 8207589 complement(144228..145100) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10320570, 16720376, 16201966, 15805527; Product type e : enzyme; DNA glycosylase MutY 145100 mutY 8207589 mutY Helicobacter pylori B38 DNA glycosylase MutY YP_003056963.1 144228 R 592205 CDS YP_003056964.1 254778859 8208792 complement(145215..146663) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9696764; Product type t : transporter; sodium/sulfate symporter 146663 8208792 HELPY_0145 Helicobacter pylori B38 sodium/sulfate symporter YP_003056964.1 145215 R 592205 CDS YP_003056965.1 254778860 8207590 146833..148299 1 NC_012973.1 CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 148299 fixN 8207590 fixN Helicobacter pylori B38 cbb3-type cytochrome c oxidase subunit I YP_003056965.1 146833 D 592205 CDS YP_003056966.1 254778861 8208507 148312..149010 1 NC_012973.1 CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 149010 fixO 8208507 fixO Helicobacter pylori B38 cbb3-type cytochrome c oxidase subunit II YP_003056966.1 148312 D 592205 CDS YP_003056967.1 254778862 8208508 149018..149239 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14714103, 10985736, 9880817, 8757739, 14714103, 10736149, 9880817; Product type e : enzyme; Cytochrome c oxidase subunit Q 149239 fixQ 8208508 fixQ Helicobacter pylori B38 Cytochrome c oxidase subunit Q YP_003056967.1 149018 D 592205 CDS YP_003056968.1 254778863 8208510 149241..150119 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14714103, 10985736, 9880817, 8757739, 14714103, 10736149, 9880817; Product type e : enzyme; Cytochrome c oxidase diheme subunit 150119 fixP 8208510 fixP Helicobacter pylori B38 Cytochrome c oxidase diheme subunit YP_003056968.1 149241 D 592205 CDS YP_003056969.1 254778864 8208509 150130..150336 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 150336 8208509 HELPY_0152 Helicobacter pylori B38 hypothetical protein YP_003056969.1 150130 D 592205 CDS YP_003056970.1 254778865 8207591 150437..151021 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 151021 8207591 HELPY_0153 Helicobacter pylori B38 hypothetical protein YP_003056970.1 150437 D 592205 CDS YP_003056971.1 254778866 8207592 151034..151615 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 151615 8207592 HELPY_0154 Helicobacter pylori B38 hypothetical protein YP_003056971.1 151034 D 592205 CDS YP_003056972.1 254778867 8207593 151704..152471 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; Product type m : membrane component; hypothetical protein 152471 8207593 HELPY_0155 Helicobacter pylori B38 hypothetical protein YP_003056972.1 151704 D 592205 CDS YP_003056973.1 254778868 8207594 complement(152468..153331) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 153331 8207594 HELPY_0156 Helicobacter pylori B38 hypothetical protein YP_003056973.1 152468 R 592205 CDS YP_003056974.1 254778869 8207595 153431..154474 1 NC_012973.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 154474 recA 8207595 recA Helicobacter pylori B38 recombinase A YP_003056974.1 153431 D 592205 CDS YP_003056975.1 254778870 8208905 154484..155767 1 NC_012973.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 155767 eno 8208905 eno Helicobacter pylori B38 phosphopyruvate hydratase YP_003056975.1 154484 D 592205 CDS YP_003056976.1 254778871 8208485 155760..156035 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 156035 8208485 HELPY_0159 Helicobacter pylori B38 hypothetical protein YP_003056976.1 155760 D 592205 CDS YP_003056977.1 254778872 8207596 156046..156648 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 156648 8207596 HELPY_0160 Helicobacter pylori B38 hypothetical protein YP_003056977.1 156046 D 592205 CDS YP_003056978.1 254778873 8207597 156653..157141 1 NC_012973.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 157141 aroK 8207597 aroK Helicobacter pylori B38 shikimate kinase YP_003056978.1 156653 D 592205 CDS YP_003056979.1 254778874 8208385 157163..158119 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 158119 8208385 HELPY_0162 Helicobacter pylori B38 hypothetical protein YP_003056979.1 157163 D 592205 CDS YP_003056980.1 254778875 8207598 complement(158116..159219) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15814825, 15556710, 9780260, 1624462, 1624461; Product type e : enzyme; LPS 1,2-glycosyltransferase 159219 rfaJ1 8207598 rfaJ1 Helicobacter pylori B38 LPS 1,2-glycosyltransferase YP_003056980.1 158116 R 592205 CDS YP_003056981.1 254778876 8208914 159373..160293 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10438788, 11777911, 10748053; Product type e : enzyme; cysteinyl-tRNA synthetase 160293 hcpD 8208914 hcpD Helicobacter pylori B38 cysteinyl-tRNA synthetase YP_003056981.1 159373 D 592205 CDS YP_003056982.1 254778877 8208616 complement(160817..161539) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 161539 8208616 HELPY_0165 Helicobacter pylori B38 hypothetical protein YP_003056982.1 160817 R 592205 CDS YP_003056983.1 254778878 8207599 complement(161540..162499) 1 NC_012973.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 162499 hemB 8207599 hemB Helicobacter pylori B38 delta-aminolevulinic acid dehydratase YP_003056983.1 161540 R 592205 CDS YP_003056984.1 254778879 8208625 complement(162533..163864) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16484186, 15109719, 10722597, 10418137; Product type r : regulator; Histidine kinase sensor protein 163864 8208625 HELPY_0168 Helicobacter pylori B38 Histidine kinase sensor protein YP_003056984.1 162533 R 592205 CDS YP_003056985.1 254778880 8207600 complement(163890..164567) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16769709, 16672598, 16484186, 1674092, 16618701, 16553882, 16539733; Product type r : regulator; transcriptional regulator 164567 ompR 8207600 ompR Helicobacter pylori B38 transcriptional regulator YP_003056985.1 163890 R 592205 CDS YP_003056986.1 254778881 8208828 complement(164810..165277) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 165277 8208828 HELPY_0170 Helicobacter pylori B38 hypothetical protein YP_003056986.1 164810 R 592205 CDS YP_003056987.1 254778882 8207601 complement(165268..165531) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 165531 8207601 HELPY_0171 Helicobacter pylori B38 hypothetical protein YP_003056987.1 165268 R 592205 CDS YP_003056988.1 254778883 8207602 complement(165565..166845) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protease 166845 8207602 HELPY_0172 Helicobacter pylori B38 protease YP_003056988.1 165565 R 592205 CDS YP_003056989.1 254778884 8207603 complement(166848..167579) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 167579 8207603 HELPY_0173 Helicobacter pylori B38 hypothetical protein YP_003056989.1 166848 R 592205 CDS YP_003056990.1 254778885 8207604 complement(167649..168740) 1 NC_012973.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 168740 prfB 8207604 prfB Helicobacter pylori B38 peptide chain release factor 2 YP_003056990.1 167649 R 592205 CDS YP_003056991.1 254778886 8208874 complement(168801..169976) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11934270, 12382055, 12420167, 12006571, 9515915, 9851041, 9388540; Product type f : factor; molybdopterin biosynthesis protein MoeA 169976 moeA 8208874 moeA Helicobacter pylori B38 molybdopterin biosynthesis protein MoeA YP_003056991.1 168801 R 592205 CDS YP_003056992.1 254778887 8208772 complement(169986..170753) 1 NC_012973.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 170753 fliR 8208772 fliR Helicobacter pylori B38 flagellar biosynthesis protein FliR YP_003056992.1 169986 R 592205 CDS YP_003056993.1 254778888 8208544 complement(170747..171475) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; Product type pm : membrane component; hypothetical protein 171475 8208544 HELPY_0177 Helicobacter pylori B38 hypothetical protein YP_003056993.1 170747 R 592205 CDS YP_003056994.1 254778889 8207605 171948..172847 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2186809, 7878731, 7925971, 9546151; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase C 172847 ppiC 8207605 ppiC Helicobacter pylori B38 peptidyl-prolyl cis-trans isomerase C YP_003056994.1 171948 D 592205 CDS YP_003056995.1 254778890 8208869 172864..173787 1 NC_012973.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 173787 fba 8208869 fba Helicobacter pylori B38 fructose-bisphosphate aldolase YP_003056995.1 172864 D 592205 CDS YP_003056996.1 254778891 8208498 173809..174372 1 NC_012973.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 174372 efp 8208498 efp Helicobacter pylori B38 elongation factor P YP_003056996.1 173809 D 592205 CDS YP_003056997.1 254778892 8208483 complement(174875..175903) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10873658, 10712693; Product type e : enzyme; sialic acid synthase 175903 neuB 8208483 neuB Helicobacter pylori B38 sialic acid synthase YP_003056997.1 174875 R 592205 CDS YP_003056998.1 254778893 8208798 complement(175907..176548) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16400872, 16092522, 15749056, 1531323, 10518715, 9593292; Product type t : transporter; ABC transporter ATP-binding protein 176548 8208798 HELPY_0183 Helicobacter pylori B38 ABC transporter ATP-binding protein YP_003056998.1 175907 R 592205 CDS YP_003056999.1 254778894 8207606 complement(176545..177822) 1 NC_012973.1 transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 177822 lnt 8207606 lnt Helicobacter pylori B38 apolipoprotein N-acyltransferase YP_003056999.1 176545 R 592205 CDS YP_003057000.1 254778895 8208732 178053..178754 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 178754 8208732 HELPY_0185 Helicobacter pylori B38 hypothetical protein YP_003057000.1 178053 D 592205 CDS YP_003057001.1 254778896 8207607 178764..180269 1 NC_012973.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 180269 lysS 8207607 lysS Helicobacter pylori B38 lysyl-tRNA synthetase YP_003057001.1 178764 D 592205 CDS YP_003057002.1 254778897 8208747 180269..181519 1 NC_012973.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 181519 glyA 8208747 glyA Helicobacter pylori B38 serine hydroxymethyltransferase YP_003057002.1 180269 D 592205 CDS YP_003057003.1 254778898 8208593 181530..182072 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 182072 8208593 HELPY_0188 Helicobacter pylori B38 hypothetical protein YP_003057003.1 181530 D 592205 CDS YP_003057004.1 254778899 8207608 182094..182897 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 182897 8207608 HELPY_0189 Helicobacter pylori B38 hypothetical protein YP_003057004.1 182094 D 592205 CDS YP_003057005.1 254778900 8207611 185156..185689 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 185689 8207611 HELPY_0192 Helicobacter pylori B38 hypothetical protein YP_003057005.1 185156 D 592205 CDS YP_003057006.1 254778901 8207612 complement(185695..187203) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phospholipase D 187203 8207612 HELPY_0193 Helicobacter pylori B38 phospholipase D YP_003057006.1 185695 R 592205 CDS YP_003057007.1 254778902 8207613 complement(187225..187962) 1 NC_012973.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 187962 frdB 8207613 frdB Helicobacter pylori B38 fumarate reductase iron-sulfur subunit YP_003057007.1 187225 R 592205 CDS YP_003057008.1 254778903 8208555 complement(187955..190099) 1 NC_012973.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 190099 frdA 8208555 frdA Helicobacter pylori B38 fumarate reductase flavoprotein subunit YP_003057008.1 187955 R 592205 CDS YP_003057009.1 254778904 8208554 complement(190109..190876) 1 NC_012973.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit 190876 frdC 8208554 frdC Helicobacter pylori B38 fumarate reductase cytochrome b-556 subunit YP_003057009.1 190109 R 592205 CDS YP_003057010.1 254778905 8208556 191092..191796 1 NC_012973.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 191796 tpiA 8208556 tpiA Helicobacter pylori B38 triosephosphate isomerase YP_003057010.1 191092 D 592205 CDS YP_003057011.1 254778906 8209047 191806..192633 1 NC_012973.1 [NADH]; Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 192633 8209047 HELPY_0198 Helicobacter pylori B38 enoyl-(acyl carrier protein) reductase YP_003057011.1 191806 D 592205 CDS YP_003057012.1 254778907 8207614 192643..193653 1 NC_012973.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 193653 lpxD 8207614 lpxD Helicobacter pylori B38 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_003057012.1 192643 D 592205 CDS YP_003057013.1 254778908 8208741 193718..194875 1 NC_012973.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 194875 metK 8208741 metK Helicobacter pylori B38 S-adenosylmethionine synthetase YP_003057013.1 193718 D 592205 CDS YP_003057014.1 254778909 8208753 194942..195355 1 NC_012973.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 195355 ndk 8208753 ndk Helicobacter pylori B38 nucleoside diphosphate kinase YP_003057014.1 194942 D 592205 CDS YP_003057015.1 254778910 8208797 195381..195737 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 195737 8208797 HELPY_0202 Helicobacter pylori B38 hypothetical protein YP_003057015.1 195381 D 592205 CDS YP_003057016.1 254778911 8207615 195753..195899 1 NC_012973.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 195899 rpmF 8207615 rpmF Helicobacter pylori B38 50S ribosomal protein L32 YP_003057016.1 195753 D 592205 CDS YP_003057017.1 254778912 8208965 195963..196985 1 NC_012973.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 196985 plsX 8208965 plsX Helicobacter pylori B38 glycerol-3-phosphate acyltransferase PlsX YP_003057017.1 195963 D 592205 CDS YP_003057018.1 254778913 8208860 197010..198002 1 NC_012973.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 198002 fabH 8208860 fabH Helicobacter pylori B38 3-oxoacyl-ACP synthase YP_003057018.1 197010 D 592205 CDS YP_003057019.1 254778914 8208496 198023..198325 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 198325 8208496 HELPY_0206 Helicobacter pylori B38 hypothetical protein YP_003057019.1 198023 D 592205 CDS YP_003057020.1 254778915 8207616 complement(198951..199334) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 199334 8207616 HELPY_0207 Helicobacter pylori B38 hypothetical protein YP_003057020.1 198951 R 592205 CDS YP_003057021.1 254778916 8207619 202476..203582 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9600981; Product type e : enzyme; ATP-binding protein 203582 mrp 8207619 mrp Helicobacter pylori B38 ATP-binding protein YP_003057021.1 202476 D 592205 CDS YP_003057022.1 254778917 8208781 complement(203596..204768) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15814825, 15556710, 9780260, 1624462, 1624461; Product type e : enzyme; LPS 1,2-glycosyltransferase 204768 rfaJ2 8208781 rfaJ2 Helicobacter pylori B38 LPS 1,2-glycosyltransferase YP_003057022.1 203596 R 592205 CDS YP_003057023.1 254778918 8208915 204927..206279 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type pm : membrane component; outer membrane protein HofA 206279 hofA 8208915 hofA Helicobacter pylori B38 outer membrane protein HofA YP_003057023.1 204927 D 592205 CDS YP_003057024.1 254778919 8208636 206382..208247 1 NC_012973.1 molecular chaperone; heat shock protein 90 208247 htpG 8208636 htpG Helicobacter pylori B38 heat shock protein 90 YP_003057024.1 206382 D 592205 CDS YP_003057025.1 254778920 8208693 complement(208444..209196) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10748053, 11777911, 9317022, 9596777; Product type e : enzyme; Cysteine-rich protein A 209196 hcpA 8208693 hcpA Helicobacter pylori B38 Cysteine-rich protein A YP_003057025.1 208444 R 592205 CDS YP_003057026.1 254778921 8208614 complement(209655..210806) 1 NC_012973.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 210806 dapE 8208614 dapE Helicobacter pylori B38 succinyl-diaminopimelate desuccinylase YP_003057026.1 209655 R 592205 CDS YP_003057027.1 254778922 8208451 complement(210817..212682) 1 NC_012973.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 212682 gidA 8208451 gidA Helicobacter pylori B38 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_003057027.1 210817 R 592205 CDS YP_003057028.1 254778923 8208582 212778..214436 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; symtransporter; membrane protein 214436 8208582 HELPY_0217 Helicobacter pylori B38 symtransporter; membrane protein YP_003057028.1 212778 D 592205 CDS YP_003057029.1 254778924 8207620 214449..215249 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2995359; Product type e : enzyme; phosphatidate cytidylyltransferase 215249 cdsA 8207620 cdsA Helicobacter pylori B38 phosphatidate cytidylyltransferase YP_003057029.1 214449 D 592205 CDS YP_003057030.1 254778925 8208417 215250..216356 1 NC_012973.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 216356 dxr 8208417 dxr Helicobacter pylori B38 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_003057030.1 215250 D 592205 CDS YP_003057031.1 254778926 8207622 complement(217563..218114) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11439028; hypothetical protein 218114 8207622 HELPY_0222 Helicobacter pylori B38 hypothetical protein YP_003057031.1 217563 R 592205 CDS YP_003057032.1 254778927 8207623 218259..218720 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 218720 8207623 HELPY_0223 Helicobacter pylori B38 hypothetical protein YP_003057032.1 218259 D 592205 CDS YP_003057033.1 254778928 8207624 218891..220054 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11123951, 16185064, 15952888, 15667274, 1219616, 8482384; Product type e : enzyme; cysteine desulfurase 220054 nifS 8207624 nifS Helicobacter pylori B38 cysteine desulfurase YP_003057033.1 218891 D 592205 CDS YP_003057034.1 254778929 8208800 220076..221056 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11123951, 16185064, 15952888, 15667274, 1219616, 8482384; Product type f : factor; [Fe-S] cluster scaffold protein 221056 nifU 8208800 nifU Helicobacter pylori B38 [Fe-S] cluster scaffold protein YP_003057034.1 220076 D 592205 CDS YP_003057035.1 254778930 8207626 221557..222903 1 NC_012973.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 222903 radA 8207626 radA Helicobacter pylori B38 DNA repair protein RadA YP_003057035.1 221557 D 592205 CDS YP_003057036.1 254778931 8208901 223017..224096 1 NC_012973.1 [peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (peptide Met(O) reductase); peptide methionine sulfoxide reductase MsrB]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15387818, 7836279, 7017726, 1386361, 8755589, 9596777; Product type e : enzyme; peptide methionine sulfoxide reductase 224096 msr 8208901 msr Helicobacter pylori B38 peptide methionine sulfoxide reductase YP_003057036.1 223017 D 592205 CDS YP_003057037.1 254778932 8208782 complement(224528..225361) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 225361 8208782 HELPY_0230 Helicobacter pylori B38 hypothetical protein YP_003057037.1 224528 R 592205 CDS YP_003057038.1 254778933 8207627 complement(225574..227664) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopM 227664 hopM 8207627 hopM Helicobacter pylori B38 outer membrane protein HopM YP_003057038.1 225574 R 592205 CDS YP_003057039.1 254778934 8208661 227919..229076 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7616962; Product type pt : transporter; sulfate permease 229076 8208661 HELPY_0232 Helicobacter pylori B38 sulfate permease YP_003057039.1 227919 D 592205 CDS YP_003057040.1 254778935 8208347 complement(229311..230762) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7534278, 7559328, 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopA 230762 hopA 8208347 hopA Helicobacter pylori B38 outer membrane protein HopA YP_003057040.1 229311 R 592205 CDS YP_003057041.1 254778936 8208648 complement(230956..231687) 1 NC_012973.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 231687 kdsB 8208648 kdsB Helicobacter pylori B38 3-deoxy-manno-octulosonate cytidylyltransferase YP_003057041.1 230956 R 592205 CDS YP_003057042.1 254778937 8208723 231794..232591 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 232591 8208723 HELPY_0235 Helicobacter pylori B38 hypothetical protein YP_003057042.1 231794 D 592205 CDS YP_003057043.1 254778938 8207629 232607..233257 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 8733234; Product type pf : factor; hypothetical protein 233257 8207629 HELPY_0236 Helicobacter pylori B38 hypothetical protein YP_003057043.1 232607 D 592205 CDS YP_003057044.1 254778939 8207630 233281..234453 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7775463; Product type e : enzyme; glutathionylspermidine synthase 234453 gsp 8207630 gsp Helicobacter pylori B38 glutathionylspermidine synthase YP_003057044.1 233281 D 592205 CDS YP_003057045.1 254778940 8208607 234453..234983 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 234983 8208607 HELPY_0239 Helicobacter pylori B38 hypothetical protein YP_003057045.1 234453 D 592205 CDS YP_003057046.1 254778941 8207631 complement(235702..236769) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10438788, 10748053, 11777911, 12853383; Product type pe : enzyme; Cysteine-rich protein E; beta-lactamase HcpE 236769 hcpE 8207631 hcpE Helicobacter pylori B38 Cysteine-rich protein E; beta-lactamase HcpE YP_003057046.1 235702 R 592205 CDS YP_003057047.1 254778942 8208617 complement(236863..237234) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 237234 8208617 HELPY_0241 Helicobacter pylori B38 hypothetical protein YP_003057047.1 236863 R 592205 CDS YP_003057048.1 254778943 8207632 complement(237234..238154) 1 NC_012973.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 238154 hemC 8207632 hemC Helicobacter pylori B38 porphobilinogen deaminase YP_003057048.1 237234 R 592205 CDS YP_003057049.1 254778944 8208626 complement(238165..239898) 1 NC_012973.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 239898 proS 8208626 proS Helicobacter pylori B38 prolyl-tRNA synthetase YP_003057049.1 238165 R 592205 CDS YP_003057050.1 254778945 8208878 complement(239902..241251) 1 NC_012973.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 241251 hemA 8208878 hemA Helicobacter pylori B38 glutamyl-tRNA reductase YP_003057050.1 239902 R 592205 CDS YP_003057051.1 254778946 8208624 complement(241251..242174) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16257556, 11108713, 9139929, 8037730; Product type e : enzyme; Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase) 242174 ispB 8208624 ispB Helicobacter pylori B38 Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase) YP_003057051.1 241251 R 592205 CDS YP_003057052.1 254778947 8208716 complement(242184..242579) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 242579 8208716 HELPY_0246 Helicobacter pylori B38 hypothetical protein YP_003057052.1 242184 R 592205 CDS YP_003057053.1 254778948 8207633 complement(242572..242856) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 242856 8207633 HELPY_0247 Helicobacter pylori B38 hypothetical protein YP_003057053.1 242572 R 592205 CDS YP_003057054.1 254778949 8207634 complement(242877..243311) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10790419, 10564468, 16298743, 16041003, 15788154, 15637768, 12748264; Product type ph : phenotype; Neutrophil activating protein NapA (bacterioferritin) 243311 napA 8207634 napA Helicobacter pylori B38 Neutrophil activating protein NapA (bacterioferritin) YP_003057054.1 242877 R 592205 CDS YP_003057055.1 254778950 8208796 complement(243517..244662) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8346225; Product type r : regulator; signal-transducing protein AtoS, histidine kinase 244662 8208796 HELPY_0249 Helicobacter pylori B38 signal-transducing protein AtoS, histidine kinase YP_003057055.1 243517 R 592205 CDS YP_003057056.1 254778951 8207635 complement(244659..244976) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 244976 8207635 HELPY_0250 Helicobacter pylori B38 hypothetical protein YP_003057056.1 244659 R 592205 CDS YP_003057057.1 254778952 8207636 complement(244973..246001) 1 NC_012973.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 246001 flgI 8207636 flgI Helicobacter pylori B38 flagellar basal body P-ring protein YP_003057057.1 244973 R 592205 CDS YP_003057058.1 254778953 8208524 246190..247668 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1552844, 16352840, 16337753; Product type e : enzyme; ATP-dependent RNA helicase, DEAD-box family DEAD 247668 deaD 8208524 deaD Helicobacter pylori B38 ATP-dependent RNA helicase, DEAD-box family DEAD YP_003057058.1 246190 D 592205 CDS YP_003057059.1 254778954 8208456 247689..248777 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 248777 8208456 HELPY_0253 Helicobacter pylori B38 hypothetical protein YP_003057059.1 247689 D 592205 CDS YP_003057060.1 254778955 8207637 248784..249323 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 249323 8207637 HELPY_0254 Helicobacter pylori B38 hypothetical protein YP_003057060.1 248784 D 592205 CDS YP_003057061.1 254778956 8207638 complement(249374..250924) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter ATP-binding protein 250924 8207638 HELPY_0255 Helicobacter pylori B38 ABC transporter ATP-binding protein YP_003057061.1 249374 R 592205 CDS YP_003057062.1 254778957 8208345 252293..253750 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10454640; Product type m : membrane component; outer membrane protein HopF 253750 hopF 8208345 hopF Helicobacter pylori B38 outer membrane protein HopF YP_003057062.1 252293 D 592205 CDS YP_003057063.1 254778958 8208653 253763..255175 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10454640; Product type m : membrane component; outer membrane protein HopG 255175 hopG 8208653 hopG Helicobacter pylori B38 outer membrane protein HopG YP_003057063.1 253763 D 592205 CDS YP_003057064.1 254778959 8208654 255274..256509 1 NC_012973.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 256509 purA 8208654 purA Helicobacter pylori B38 adenylosuccinate synthetase YP_003057064.1 255274 D 592205 CDS YP_003057065.1 254778960 8208885 256506..256934 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 256934 8208885 HELPY_0261 Helicobacter pylori B38 hypothetical protein YP_003057065.1 256506 D 592205 CDS YP_003057066.1 254778961 8207642 256927..257598 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 257598 8207642 HELPY_0262 Helicobacter pylori B38 hypothetical protein YP_003057066.1 256927 D 592205 CDS YP_003057067.1 254778962 8207643 257598..258644 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase M50 (membrane-associated zinc metallopeptidase), MEROPS family; membrane protein 258644 8207643 HELPY_0263 Helicobacter pylori B38 peptidase M50 (membrane-associated zinc metallopeptidase), MEROPS family; membrane protein YP_003057067.1 257598 D 592205 CDS YP_003057068.1 254778963 8207644 258657..259919 1 NC_012973.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 259919 xseA 8207644 xseA Helicobacter pylori B38 exodeoxyribonuclease VII large subunit YP_003057068.1 258657 D 592205 CDS YP_003057069.1 254778964 8209093 complement(259939..261111) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11133936, 10954588; Product type e : enzyme; TCGA site-specific m6A methyltransferase 261111 8209093 HELPY_0265 Helicobacter pylori B38 TCGA site-specific m6A methyltransferase YP_003057069.1 259939 R 592205 CDS YP_003057070.1 254778965 8207645 complement(261104..261346) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 261346 8207645 HELPY_0266 Helicobacter pylori B38 hypothetical protein YP_003057070.1 261104 R 592205 CDS YP_003057071.1 254778966 8207648 262117..262875 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11226310, 10944229, 10954588; Product type e : enzyme; Non-functional cytosine methyltransferase 262875 hpy99VIIIM 8207648 hpy99VIIIM Helicobacter pylori B38 Non-functional cytosine methyltransferase YP_003057071.1 262117 D 592205 CDS YP_003057072.1 254778967 8208677 262948..265518 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1906060, 8885261, 2185473, 9651675, 16289019; Product type f : factor; ATP-dependent protease binding subunit/heat shock protein 265518 clpB 8208677 clpB Helicobacter pylori B38 ATP-dependent protease binding subunit/heat shock protein YP_003057072.1 262948 D 592205 CDS YP_003057073.1 254778968 8208426 265572..266294 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16109941, 15159384; Product type m : membrane component; Cytochrome C biogenesis protein; membrane protein 266294 ccdA 8208426 ccdA Helicobacter pylori B38 Cytochrome C biogenesis protein; membrane protein YP_003057073.1 265572 D 592205 CDS YP_003057074.1 254778969 8208414 266304..267437 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16522191, 15278241, 858905, 16255137, 10938275, 7928775; Product type e : enzyme; Dihydroorotase (DHOase) 267437 pyrC 8208414 pyrC Helicobacter pylori B38 Dihydroorotase (DHOase) YP_003057074.1 266304 D 592205 CDS YP_003057075.1 254778970 8208892 267425..268651 1 NC_012973.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 268651 8208892 HELPY_0273 Helicobacter pylori B38 chlorohydrolase YP_003057075.1 267425 D 592205 CDS YP_003057076.1 254778971 8207649 268711..268953 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 268953 8207649 HELPY_0274 Helicobacter pylori B38 hypothetical protein YP_003057076.1 268711 D 592205 CDS YP_003057077.1 254778972 8207650 268963..270276 1 NC_012973.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 270276 8207650 HELPY_0275 Helicobacter pylori B38 (dimethylallyl)adenosine tRNA methylthiotransferase YP_003057077.1 268963 D 592205 CDS YP_003057078.1 254778973 8207651 270316..270969 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 270969 8207651 HELPY_0276 Helicobacter pylori B38 hypothetical protein YP_003057078.1 270316 D 592205 CDS YP_003057079.1 254778974 8207652 270962..271942 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 271942 8207652 HELPY_0277 Helicobacter pylori B38 hypothetical protein YP_003057079.1 270962 D 592205 CDS YP_003057080.1 254778975 8207653 271932..272465 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 272465 8207653 HELPY_0278 Helicobacter pylori B38 hypothetical protein YP_003057080.1 271932 D 592205 CDS YP_003057081.1 254778976 8207654 272462..273001 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 273001 8207654 HELPY_0279 Helicobacter pylori B38 hypothetical protein YP_003057081.1 272462 D 592205 CDS YP_003057082.1 254778977 8207655 273018..273416 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 273416 8207655 HELPY_0280 Helicobacter pylori B38 hypothetical protein YP_003057082.1 273018 D 592205 CDS YP_003057083.1 254778978 8207656 273453..274748 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 274748 8207656 HELPY_0281 Helicobacter pylori B38 hypothetical protein YP_003057083.1 273453 D 592205 CDS YP_003057084.1 254778979 8207657 274793..275293 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 275293 8207657 HELPY_0282 Helicobacter pylori B38 hypothetical protein YP_003057084.1 274793 D 592205 CDS YP_003057085.1 254778980 8207658 275350..275604 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15866207, 12700272, 10898687; Product type pc : carrier; 4Fe-4S ferredoxin 275604 8207658 HELPY_0283 Helicobacter pylori B38 4Fe-4S ferredoxin YP_003057085.1 275350 D 592205 CDS YP_003057086.1 254778981 8207659 275614..277068 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2005135, 9882669, 15248747, 8394006; Product type e : enzyme; guanosine pentaphosphate phosphohydrolase 277068 gppA 8207659 gppA Helicobacter pylori B38 guanosine pentaphosphate phosphohydrolase YP_003057086.1 275614 D 592205 CDS YP_003057087.1 254778982 8208601 277065..278075 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8478319, 9446588, 16109967, 12591937, 11717579, 11054112; Product type e : enzyme; Lipopolysaccharide heptosyltransferase 1 278075 waaC 8208601 waaC Helicobacter pylori B38 Lipopolysaccharide heptosyltransferase 1 YP_003057087.1 277065 D 592205 CDS YP_003057088.1 254778983 8209090 278072..279058 1 NC_012973.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 279058 waaM 8209090 waaM Helicobacter pylori B38 lipid A biosynthesis lauroyl acyltransferase YP_003057088.1 278072 D 592205 CDS YP_003057089.1 254778984 8209091 complement(279129..280244) 1 NC_012973.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 280244 tgt 8209091 tgt Helicobacter pylori B38 queuine tRNA-ribosyltransferase YP_003057089.1 279129 R 592205 CDS YP_003057090.1 254778985 8209028 280295..281737 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 281737 8209028 HELPY_0288 Helicobacter pylori B38 hypothetical protein YP_003057090.1 280295 D 592205 CDS YP_003057091.1 254778986 8207660 281742..282773 1 NC_012973.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 282773 aroB 8207660 aroB Helicobacter pylori B38 3-dehydroquinate synthase YP_003057091.1 281742 D 592205 CDS YP_003057092.1 254778987 8208381 282764..284335 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 284335 8208381 HELPY_0290 Helicobacter pylori B38 hypothetical protein YP_003057092.1 282764 D 592205 CDS YP_003057093.1 254778988 8207661 284332..285588 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11882645, 15339930; Product type pe : enzyme; MiaB-like tRNA modifying enzyme 285588 8207661 HELPY_0291 Helicobacter pylori B38 MiaB-like tRNA modifying enzyme YP_003057093.1 284332 D 592205 CDS YP_003057094.1 254778989 8207662 285575..287227 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 18421140, 8892813, 9244252, 8550601, 9560419; Product type e : enzyme; Cell division protein FtsH 287227 ftsH1 8207662 ftsH1 Helicobacter pylori B38 Cell division protein FtsH YP_003057094.1 285575 D 592205 CDS YP_003057095.1 254778990 8208563 287230..287748 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 287748 8208563 HELPY_0293 Helicobacter pylori B38 hypothetical protein YP_003057095.1 287230 D 592205 CDS YP_003057096.1 254778991 8207663 287761..288234 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 288234 8207663 HELPY_0294 Helicobacter pylori B38 hypothetical protein YP_003057096.1 287761 D 592205 CDS YP_003057097.1 254778992 8207664 288302..297028 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16610017, 16579839, 16579837, 16552038, 16497614, 16489309; Product type pm : membrane component; toxin-like outer membrane protein/vacuolating cytotoxin VacA 297028 8207664 HELPY_0295 Helicobacter pylori B38 toxin-like outer membrane protein/vacuolating cytotoxin VacA YP_003057097.1 288302 D 592205 CDS YP_003057098.1 254778993 8207665 297076..298293 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511157, 14633099, 12355264; Product type e : enzyme; Diaminopimelate decarboxylas (DAP decarboxylase) 298293 lysA 8207665 lysA Helicobacter pylori B38 Diaminopimelate decarboxylas (DAP decarboxylase) YP_003057098.1 297076 D 592205 CDS YP_003057099.1 254778994 8208745 298298..298588 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3, 2, 7496998, 8000535, 15753077, 15534933; Product type pe : enzyme; chorismate mutase PheA 298588 8208745 HELPY_0297 Helicobacter pylori B38 chorismate mutase PheA YP_003057099.1 298298 D 592205 CDS YP_003057100.1 254778995 8207666 298601..299473 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 299473 8207666 HELPY_0298 Helicobacter pylori B38 hypothetical protein YP_003057100.1 298601 D 592205 CDS YP_003057101.1 254778996 8207667 299474..301153 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11450855, 11371633, 8679677, 14745019, 8472953, 2656685, 3057324; Product type e : enzyme; Para-aminobenzoate (PABA)-synthetase 301153 pabB 8207667 pabB Helicobacter pylori B38 Para-aminobenzoate (PABA)-synthetase YP_003057101.1 299474 D 592205 CDS YP_003057102.1 254778997 8208833 301348..302367 1 NC_012973.1 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 302367 amiE 8208833 amiE Helicobacter pylori B38 acylamide amidohydrolase YP_003057102.1 301348 D 592205 CDS YP_003057103.1 254778998 8208375 complement(302449..304935) 1 NC_012973.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL 304935 flgL 8208375 flgL Helicobacter pylori B38 flagellar hook-associated protein FlgL YP_003057103.1 302449 R 592205 CDS YP_003057104.1 254778999 8208526 305177..305491 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type s : structure; 50S ribosomal protein L21 305491 rplU 8208526 rplU Helicobacter pylori B38 50S ribosomal protein L21 YP_003057104.1 305177 D 592205 CDS YP_003057105.1 254779000 8208957 305506..305772 1 NC_012973.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 305772 rpmA 8208957 rpmA Helicobacter pylori B38 50S ribosomal protein L27 YP_003057105.1 305506 D 592205 CDS YP_003057106.1 254779001 8208962 305889..307538 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 8527431, 1956284, 15845494, 14568145; Product type t : transporter; peptide ABC transporter substrate-binding protein 307538 dppA 8208962 dppA Helicobacter pylori B38 peptide ABC transporter substrate-binding protein YP_003057106.1 305889 D 592205 CDS YP_003057107.1 254779002 8208472 307549..308553 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 14568145, 11858173, 7536291; Product type t : transporter; ABC transporter permease; dipeptide transporter protein 2; membrane protein 308553 dppB 8208472 dppB Helicobacter pylori B38 ABC transporter permease; dipeptide transporter protein 2; membrane protein YP_003057107.1 307549 D 592205 CDS YP_003057108.1 254779003 8208473 308553..309410 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 11858173, 9680220; Product type t : transporter; ABC transporter permease; dipeptide transporter protein 3; membrane protein 309410 dppC 8208473 dppC Helicobacter pylori B38 ABC transporter permease; dipeptide transporter protein 3; membrane protein YP_003057108.1 308553 D 592205 CDS YP_003057109.1 254779004 8208474 309422..310285 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 11858173, 9680220; Product type t : transporter; ABC transporter ATP-binding protein; dipeptide transporter protein 4 310285 dppD 8208474 dppD Helicobacter pylori B38 ABC transporter ATP-binding protein; dipeptide transporter protein 4 YP_003057109.1 309422 D 592205 CDS YP_003057110.1 254779005 8208475 310282..311088 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 11858173, 9680220, 7536291; Product type t : transporter; ABC transporter ATP-binding protein; dipeptide transporter protein 5 311088 dppF 8208475 dppF Helicobacter pylori B38 ABC transporter ATP-binding protein; dipeptide transporter protein 5 YP_003057110.1 310282 D 592205 CDS YP_003057111.1 254779006 8208476 311107..312189 1 NC_012973.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 312189 obgE 8208476 obgE Helicobacter pylori B38 GTPase ObgE YP_003057111.1 311107 D 592205 CDS YP_003057112.1 254779007 8207668 312231..313226 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 313226 8207668 HELPY_0311 Helicobacter pylori B38 hypothetical protein YP_003057112.1 312231 D 592205 CDS YP_003057113.1 254779008 8207669 313492..314046 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 314046 8207669 HELPY_0312 Helicobacter pylori B38 hypothetical protein YP_003057113.1 313492 D 592205 CDS YP_003057114.1 254779009 8207670 314056..315348 1 NC_012973.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 315348 hemL 8207670 hemL Helicobacter pylori B38 glutamate-1-semialdehyde aminotransferase YP_003057114.1 314056 D 592205 CDS YP_003057115.1 254779010 8208631 315345..315617 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 315617 8208631 HELPY_0314 Helicobacter pylori B38 hypothetical protein YP_003057115.1 315345 D 592205 CDS YP_003057116.1 254779011 8207671 315633..316037 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; Product type pm : membrane component; hypothetical protein 316037 8207671 HELPY_0315 Helicobacter pylori B38 hypothetical protein YP_003057116.1 315633 D 592205 CDS YP_003057117.1 254779012 8207672 316121..316999 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7987228, 11380987, 12054553; Product type pe : enzyme; N-carbomoyl-D-amino acid amidohydrolase 316999 8207672 HELPY_0316 Helicobacter pylori B38 N-carbomoyl-D-amino acid amidohydrolase YP_003057117.1 316121 D 592205 CDS YP_003057118.1 254779013 8207673 317012..317893 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9163424, 8170399, 9163415; Product type pe : enzyme; NodB-like polysaccharide deacetylase 317893 8207673 HELPY_0317 Helicobacter pylori B38 NodB-like polysaccharide deacetylase YP_003057118.1 317012 D 592205 CDS YP_003057119.1 254779014 8207674 317939..318316 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 318316 8207674 HELPY_0318 Helicobacter pylori B38 hypothetical protein YP_003057119.1 317939 D 592205 CDS YP_003057120.1 254779015 8207675 318316..319278 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1655697, 1624427, 8423137, 9209019, 9140970; Product type pf : factor; cobalamin syntheis protein, P47K family; ATP/GTP binding protein 319278 8207675 HELPY_0319 Helicobacter pylori B38 cobalamin syntheis protein, P47K family; ATP/GTP binding protein YP_003057120.1 318316 D 592205 CDS YP_003057121.1 254779016 8207676 complement(319284..320426) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17347820; Product type pt : transporter; nitrite extrusion protein, major facilitator family protein; membrane protein 320426 8207676 HELPY_0320 Helicobacter pylori B38 nitrite extrusion protein, major facilitator family protein; membrane protein YP_003057121.1 319284 R 592205 CDS YP_003057122.1 254779017 8207677 complement(320936..321694) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 321694 8207677 HELPY_0321 Helicobacter pylori B38 hypothetical protein YP_003057122.1 320936 R 592205 CDS YP_003057123.1 254779018 8207678 complement(321805..323430) 1 NC_012973.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 323430 argS 8207678 argS Helicobacter pylori B38 arginyl-tRNA synthetase YP_003057123.1 321805 R 592205 CDS YP_003057124.1 254779019 8208379 complement(323433..323672) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16291683, 16027357, 12867413, 11591389, 11422364, 11350936; Product type t : transporter; Sec-independent protein translocase protein tatA/E-like protein 323672 tatA 8208379 tatA Helicobacter pylori B38 Sec-independent protein translocase protein tatA/E-like protein YP_003057124.1 323433 R 592205 CDS YP_003057125.1 254779020 8209025 complement(323744..324364) 1 NC_012973.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 324364 gmk 8209025 gmk Helicobacter pylori B38 guanylate kinase YP_003057125.1 323744 R 592205 CDS YP_003057126.1 254779021 8208599 complement(324357..325700) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 325700 8208599 HELPY_0325 Helicobacter pylori B38 hypothetical protein YP_003057126.1 324357 R 592205 CDS YP_003057127.1 254779022 8207679 325844..326386 1 NC_012973.1 membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT 326386 8207679 HELPY_0326 Helicobacter pylori B38 nuclease NucT YP_003057127.1 325844 D 592205 CDS YP_003057128.1 254779023 8207680 complement(326396..327133) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HorC 327133 horC 8207680 horC Helicobacter pylori B38 outer membrane protein HorC YP_003057128.1 326396 R 592205 CDS YP_003057129.1 254779024 8208667 327274..327987 1 NC_012973.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 327987 flgH 8208667 flgH Helicobacter pylori B38 flagellar basal body L-ring protein YP_003057129.1 327274 D 592205 CDS YP_003057130.1 254779025 8207682 329554..330096 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2921244, 9748431, 15687208, 15361076, 10559162; Product type ps : structure; flagellar biosynthesis protein 330096 8207682 HELPY_0331 Helicobacter pylori B38 flagellar biosynthesis protein YP_003057130.1 329554 D 592205 CDS YP_003057131.1 254779026 8207683 complement(330029..330967) 1 NC_012973.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 330967 lpxK 8207683 lpxK Helicobacter pylori B38 tetraacyldisaccharide 4'-kinase YP_003057131.1 330029 R 592205 CDS YP_003057132.1 254779027 8208742 complement(330964..331746) 1 NC_012973.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 331746 nadE 8208742 nadE Helicobacter pylori B38 NAD synthetase YP_003057132.1 330964 R 592205 CDS YP_003057133.1 254779028 8208335 331998..332990 1 NC_012973.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 332990 ilvC 8208335 ilvC Helicobacter pylori B38 ketol-acid reductoisomerase YP_003057133.1 331998 D 592205 CDS YP_003057134.1 254779029 8208709 333014..333820 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16585760, 16584194, 2645057, 10220403, 1836760, 11566131, 16376524; Product type e : enzyme; Cell division inhibitor MinD 333820 minD 8208709 minD Helicobacter pylori B38 Cell division inhibitor MinD YP_003057134.1 333014 D 592205 CDS YP_003057135.1 254779030 8208759 333817..334050 1 NC_012973.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 334050 minE 8208759 minE Helicobacter pylori B38 cell division topological specificity factor MinE YP_003057135.1 333817 D 592205 CDS YP_003057136.1 254779031 8208760 334057..334857 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10482496, 10640603, 16194595, 14617176, 12123453, 11823215; Product type f : factor; DNA processing chain A (DprA) 334857 dprA 8208760 dprA Helicobacter pylori B38 DNA processing chain A (DprA) YP_003057136.1 334057 D 592205 CDS YP_003057137.1 254779032 8208477 334854..335258 1 NC_012973.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 335258 8208477 HELPY_0338 Helicobacter pylori B38 Holliday junction resolvase-like protein YP_003057137.1 334854 D 592205 CDS YP_003057138.1 254779033 8207684 335452..336045 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9596777, 11777911, 12853383, 15223324; Product type e : enzyme; hypothetical protein 336045 hcpH 8207684 hcpH Helicobacter pylori B38 hypothetical protein YP_003057138.1 335452 D 592205 CDS YP_003057139.1 254779034 8208619 336231..336569 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 336569 8208619 HELPY_0340 Helicobacter pylori B38 hypothetical protein YP_003057139.1 336231 D 592205 CDS YP_003057140.1 254779035 8207685 336553..337113 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 337113 8207685 HELPY_0341 Helicobacter pylori B38 hypothetical protein YP_003057140.1 336553 D 592205 CDS YP_003057141.1 254779036 8207689 338106..338492 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 338492 8207689 HELPY_0345 Helicobacter pylori B38 hypothetical protein YP_003057141.1 338106 D 592205 CDS YP_003057142.1 254779037 8207690 338492..339277 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 339277 8207690 HELPY_0346 Helicobacter pylori B38 hypothetical protein YP_003057142.1 338492 D 592205 CDS YP_003057143.1 254779038 8207694 complement(340457..341353) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9660827, 16511038, 15928344; Product type e : enzyme; Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) 341353 rluD 8207694 rluD Helicobacter pylori B38 Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) YP_003057143.1 340457 R 592205 CDS YP_003057144.1 254779039 8208926 complement(341353..342903) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2649886, 16488881, 15687199, 10498723; Product type e : enzyme; ssDNA-specific exonuclease RecJ 342903 recJ 8208926 recJ Helicobacter pylori B38 ssDNA-specific exonuclease RecJ YP_003057144.1 341353 R 592205 CDS YP_003057145.1 254779040 8208907 complement(342912..344528) 1 NC_012973.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 344528 pyrG 8208907 pyrG Helicobacter pylori B38 CTP synthetase YP_003057145.1 342912 R 592205 CDS YP_003057146.1 254779041 8208897 344783..345451 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 345451 8208897 HELPY_0353 Helicobacter pylori B38 hypothetical protein YP_003057146.1 344783 D 592205 CDS YP_003057147.1 254779042 8207695 345495..347198 1 NC_012973.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 347198 fliF 8207695 fliF Helicobacter pylori B38 flagellar MS-ring protein YP_003057147.1 345495 D 592205 CDS YP_003057148.1 254779043 8208535 347211..348242 1 NC_012973.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 348242 fliG 8208535 fliG Helicobacter pylori B38 flagellar motor switch protein G YP_003057148.1 347211 D 592205 CDS YP_003057149.1 254779044 8208536 348235..349008 1 NC_012973.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 349008 fliH 8208536 fliH Helicobacter pylori B38 flagellar assembly protein H YP_003057149.1 348235 D 592205 CDS YP_003057150.1 254779045 8208537 349005..350861 1 NC_012973.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 350861 dxs 8208537 dxs Helicobacter pylori B38 1-deoxy-D-xylulose-5-phosphate synthase YP_003057150.1 349005 D 592205 CDS YP_003057151.1 254779046 8208480 350858..352666 1 NC_012973.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 352666 lepA 8208480 lepA Helicobacter pylori B38 GTP-binding protein LepA YP_003057151.1 350858 D 592205 CDS YP_003057152.1 254779047 8208727 352681..353436 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 353436 8208727 HELPY_0359 Helicobacter pylori B38 hypothetical protein YP_003057152.1 352681 D 592205 CDS YP_003057153.1 254779048 8207696 353439..353675 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 353675 8207696 HELPY_0360 Helicobacter pylori B38 hypothetical protein YP_003057153.1 353439 D 592205 CDS YP_003057154.1 254779049 8207697 complement(354248..355057) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9931471, 15136044, 1503936; Product type s : structure; Flagellar basal-body rod protein FlgG (Distal rod protein) 355057 flgG 8207697 flgG Helicobacter pylori B38 Flagellar basal-body rod protein FlgG (Distal rod protein) YP_003057154.1 354248 R 592205 CDS YP_003057155.1 254779050 8208521 complement(355111..356397) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1556144, 10613883, 2053984; Product type t : transporter; MFS superfamily alpha-ketoglutarate permease 356397 8208521 HELPY_0362 Helicobacter pylori B38 MFS superfamily alpha-ketoglutarate permease YP_003057155.1 355111 R 592205 CDS YP_003057156.1 254779051 8207698 complement(356560..359127) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16612541, 16553881, 16452433, 16301526, 16194242, 15491352, 9748467; Product type ph : phenotype; DNA translocase FtsK; membrane protein 359127 ftsK 8207698 ftsK Helicobacter pylori B38 DNA translocase FtsK; membrane protein YP_003057156.1 356560 R 592205 CDS YP_003057157.1 254779052 8208565 complement(359124..361454) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 361454 8208565 HELPY_0364 Helicobacter pylori B38 hypothetical protein YP_003057157.1 359124 R 592205 CDS YP_003057158.1 254779053 8207699 complement(361451..363376) 1 NC_012973.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 363376 tkt 8207699 tkt Helicobacter pylori B38 transketolase YP_003057158.1 361451 R 592205 CDS YP_003057159.1 254779054 8209039 complement(363423..364265) 1 NC_012973.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 364265 ribF 8209039 ribF Helicobacter pylori B38 bifunctional riboflavin kinase/FMN adenylyltransferase YP_003057159.1 363423 R 592205 CDS YP_003057160.1 254779055 8208922 complement(364231..364938) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11179345, 12018657; Product type e : enzyme; Pore-forming cytolysin 364938 tlyA 8208922 tlyA Helicobacter pylori B38 Pore-forming cytolysin YP_003057160.1 364231 R 592205 CDS YP_003057161.1 254779056 8209042 complement(364938..365453) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 365453 8209042 HELPY_0368 Helicobacter pylori B38 hypothetical protein YP_003057161.1 364938 R 592205 CDS YP_003057162.1 254779057 8207700 365520..366443 1 NC_012973.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 366443 pyrB 8207700 pyrB Helicobacter pylori B38 aspartate carbamoyltransferase catalytic subunit YP_003057162.1 365520 D 592205 CDS YP_003057163.1 254779058 8208891 366697..368136 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10633126, 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HofB 368136 hofB 8208891 hofB Helicobacter pylori B38 outer membrane protein HofB YP_003057163.1 366697 D 592205 CDS YP_003057164.1 254779059 8208637 368227..369882 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9575204, 11546864; Product type t : transporter; ABC transporter ATP-binding protein; lipid A and glycerophospholipid transporter; membrane protein 369882 8208637 HELPY_0371 Helicobacter pylori B38 ABC transporter ATP-binding protein; lipid A and glycerophospholipid transporter; membrane protein YP_003057164.1 368227 D 592205 CDS YP_003057165.1 254779060 8207701 369876..370499 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 370499 8207701 HELPY_0372 Helicobacter pylori B38 hypothetical protein YP_003057165.1 369876 D 592205 CDS YP_003057166.1 254779061 8207702 370503..371072 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 371072 8207702 HELPY_0373 Helicobacter pylori B38 hypothetical protein YP_003057166.1 370503 D 592205 CDS YP_003057167.1 254779062 8207703 371195..372190 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11796600, 10692379, 11844775, 12890020, 16239520, 16452405, 9417070; Product type t : transporter; High-affinity nickel transporter 372190 nixA 8207703 nixA Helicobacter pylori B38 High-affinity nickel transporter YP_003057167.1 371195 D 592205 CDS YP_003057168.1 254779063 8208803 complement(372194..372709) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 372709 8208803 HELPY_0375 Helicobacter pylori B38 hypothetical protein YP_003057168.1 372194 R 592205 CDS YP_003057169.1 254779064 8207704 372844..374160 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 374160 8207704 HELPY_0376 Helicobacter pylori B38 hypothetical protein YP_003057169.1 372844 D 592205 CDS YP_003057170.1 254779065 8207705 complement(374809..375009) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9440521, 11031122; Product type f : factor; Copper-associated protein 375009 copP 8207705 copP Helicobacter pylori B38 Copper-associated protein YP_003057170.1 374809 R 592205 CDS YP_003057171.1 254779066 8208439 complement(375010..377235) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12060779, 9789554, 9244252, 8550601, 7752900, 9440521; Product type t : transporter; Copper-transporting ATPase/P-type transporting ATPase; membrane protein 377235 copA 8208439 copA Helicobacter pylori B38 Copper-transporting ATPase/P-type transporting ATPase; membrane protein YP_003057171.1 375010 R 592205 CDS YP_003057172.1 254779067 8208437 complement(377232..377945) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15031650, 16294310; Product type e : enzyme; CDP-diacylglycerol--serine O-phosphatidyltransferase 377945 pssA 8208437 pssA Helicobacter pylori B38 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_003057172.1 377232 R 592205 CDS YP_003057173.1 254779068 8208882 complement(378192..380090) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 18421140, 9560419, 8892813, 9244252, 8550601, 9440521; Product type e : enzyme; ATP-dependent zinc-metallo protease 380090 ftsH2 8208882 ftsH2 Helicobacter pylori B38 ATP-dependent zinc-metallo protease YP_003057173.1 378192 R 592205 CDS YP_003057174.1 254779069 8208564 complement(380099..381088) 1 NC_012973.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 381088 prmA 8208564 prmA Helicobacter pylori B38 50S ribosomal protein L11 methyltransferase YP_003057174.1 380099 R 592205 CDS YP_003057175.1 254779070 8208876 complement(381089..381463) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16207913, 15664919, 11535789, 10722597, 10049806, 9485379; Product type r : regulator; Chemotactic response regulator, two-component system 381463 cheY 8208876 cheY Helicobacter pylori B38 Chemotactic response regulator, two-component system YP_003057175.1 381089 R 592205 CDS YP_003057176.1 254779071 8208424 381752..382354 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614; Product type m : membrane component; outer membrane protein HorD 382354 horD 8208424 horD Helicobacter pylori B38 outer membrane protein HorD YP_003057176.1 381752 D 592205 CDS YP_003057177.1 254779072 8208344 complement(382486..382893) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 382893 8208344 HELPY_0385 Helicobacter pylori B38 hypothetical protein YP_003057177.1 382486 R 592205 CDS YP_003057178.1 254779073 8207706 complement(382896..383138) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 383138 8207706 HELPY_0386 Helicobacter pylori B38 hypothetical protein YP_003057178.1 382896 R 592205 CDS YP_003057179.1 254779074 8207707 complement(383132..383668) 1 NC_012973.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 383668 gidB 8207707 gidB Helicobacter pylori B38 16S rRNA methyltransferase GidB YP_003057179.1 383132 R 592205 CDS YP_003057180.1 254779075 8208583 complement(383665..384702) 1 NC_012973.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 384702 queA 8208583 queA Helicobacter pylori B38 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_003057180.1 383665 R 592205 CDS YP_003057181.1 254779076 8208899 complement(384703..385449) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16487318, 16343541, 11591389, 11279240, 10593889, 16092529; Product type t : transporter; Sec-independent protein translocase protein; membrane protein 385449 tatC 8208899 tatC Helicobacter pylori B38 Sec-independent protein translocase protein; membrane protein YP_003057181.1 384703 R 592205 CDS YP_003057182.1 254779077 8209027 complement(385442..385909) 1 NC_012973.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 385909 tatB 8209027 tatB Helicobacter pylori B38 sec-independent translocase YP_003057182.1 385442 R 592205 CDS YP_003057183.1 254779078 8209026 complement(385976..386986) 1 NC_012973.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 386986 ruvB 8209026 ruvB Helicobacter pylori B38 Holliday junction DNA helicase RuvB YP_003057183.1 385976 R 592205 CDS YP_003057184.1 254779079 8208997 complement(386987..387799) 1 NC_012973.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 387799 panB 8208997 panB Helicobacter pylori B38 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_003057184.1 386987 R 592205 CDS YP_003057185.1 254779080 8208836 387939..388670 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 388670 8208836 HELPY_0393 Helicobacter pylori B38 hypothetical protein YP_003057185.1 387939 D 592205 CDS YP_003057186.1 254779081 8207708 388660..389514 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 389514 8207708 HELPY_0394 Helicobacter pylori B38 hypothetical protein YP_003057186.1 388660 D 592205 CDS YP_003057187.1 254779082 8207709 389526..390467 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 390467 8207709 HELPY_0395 Helicobacter pylori B38 hypothetical protein YP_003057187.1 389526 D 592205 CDS YP_003057188.1 254779083 8207710 390477..391799 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 391799 8207710 HELPY_0396 Helicobacter pylori B38 hypothetical protein YP_003057188.1 390477 D 592205 CDS YP_003057189.1 254779084 8207711 391802..392389 1 NC_012973.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 392389 minC 8207711 minC Helicobacter pylori B38 septum formation inhibitor YP_003057189.1 391802 D 592205 CDS YP_003057190.1 254779085 8208758 392386..393273 1 NC_012973.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 393273 lpxC 8208758 lpxC Helicobacter pylori B38 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_003057190.1 392386 D 592205 CDS YP_003057191.1 254779086 8208740 393295..393768 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 393768 8208740 HELPY_0399 Helicobacter pylori B38 hypothetical protein YP_003057191.1 393295 D 592205 CDS YP_003057192.1 254779087 8207712 393822..394703 1 NC_012973.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 394703 thrB 8207712 thrB Helicobacter pylori B38 homoserine kinase YP_003057192.1 393822 D 592205 CDS YP_003057193.1 254779088 8209033 394690..394944 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 394944 8209033 HELPY_0401 Helicobacter pylori B38 hypothetical protein YP_003057193.1 394690 D 592205 CDS YP_003057194.1 254779089 8207713 394941..397775 1 NC_012973.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 397775 infB 8207713 infB Helicobacter pylori B38 translation initiation factor IF-2 YP_003057194.1 394941 D 592205 CDS YP_003057195.1 254779090 8208713 397775..398110 1 NC_012973.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 398110 rbfA 8208713 rbfA Helicobacter pylori B38 ribosome-binding factor A YP_003057195.1 397775 D 592205 CDS YP_003057196.1 254779091 8208902 398103..398543 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 398543 8208902 HELPY_0404 Helicobacter pylori B38 hypothetical protein YP_003057196.1 398103 D 592205 CDS YP_003057197.1 254779092 8207714 complement(398652..400640) 1 NC_012973.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 400640 acs 8207714 acs Helicobacter pylori B38 acetyl-CoA synthetase YP_003057197.1 398652 R 592205 CDS YP_003057198.1 254779093 8208369 400839..401951 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8683579; Product type pe : enzyme; membrane-bound phosphoesterase; membrane protein 401951 8208369 HELPY_0406 Helicobacter pylori B38 membrane-bound phosphoesterase; membrane protein YP_003057198.1 400839 D 592205 CDS YP_003057199.1 254779094 8207715 402292..402963 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; two-component response regulator 402963 8207715 HELPY_0407 Helicobacter pylori B38 two-component response regulator YP_003057199.1 402292 D 592205 CDS YP_003057200.1 254779095 8207716 403109..403285 1 NC_012973.1 Evidence 6 : Doubtful CDS; hypothetical protein 403285 8207716 HELPY_0409 Helicobacter pylori B38 hypothetical protein YP_003057200.1 403109 D 592205 CDS YP_003057201.1 254779096 8207717 complement(403292..403411) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 403411 8207717 HELPY_0410 Helicobacter pylori B38 hypothetical protein YP_003057201.1 403292 R 592205 CDS YP_003057202.1 254779097 8207718 complement(403765..404808) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9478130; Product type pe : enzyme; phosphoesterase RecJ-like 404808 8207718 HELPY_0411 Helicobacter pylori B38 phosphoesterase RecJ-like YP_003057202.1 403765 R 592205 CDS YP_003057203.1 254779098 8207719 complement(404839..407040) 1 NC_012973.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 407040 flhA 8207719 flhA Helicobacter pylori B38 flagellar biosynthesis protein FlhA YP_003057203.1 404839 R 592205 CDS YP_003057204.1 254779099 8208529 407176..407448 1 NC_012973.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 407448 rpsO 8208529 rpsO Helicobacter pylori B38 30S ribosomal protein S15 YP_003057204.1 407176 D 592205 CDS YP_003057205.1 254779100 8208989 407479..408768 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; Product type m : membrane component; hypothetical protein 408768 8208989 HELPY_0414 Helicobacter pylori B38 hypothetical protein YP_003057205.1 407479 D 592205 CDS YP_003057206.1 254779101 8207720 408899..409402 1 NC_012973.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 409402 aroQ 8207720 aroQ Helicobacter pylori B38 3-dehydroquinate dehydratase YP_003057206.1 408899 D 592205 CDS YP_003057207.1 254779102 8208386 409416..410489 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15313226, 9797327, 9421914, 6336737; Product type e : enzyme; Proline dipeptidase 410489 pepQ 8208386 pepQ Helicobacter pylori B38 Proline dipeptidase YP_003057207.1 409416 D 592205 CDS YP_003057208.1 254779103 8208847 410486..410977 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9118956, 1325970; Product type e : enzyme; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 410977 folK 8208847 folK Helicobacter pylori B38 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_003057208.1 410486 D 592205 CDS YP_003057209.1 254779104 8208552 410971..412344 1 NC_012973.1 positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 412344 flhF 8208552 flhF Helicobacter pylori B38 flagellar biosynthesis regulator FlhF YP_003057209.1 410971 D 592205 CDS YP_003057210.1 254779105 8208531 412341..413225 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15361076; Product type pf : factor; ATPAse involved in the assembly of flagella 413225 8208531 HELPY_0419 Helicobacter pylori B38 ATPAse involved in the assembly of flagella YP_003057210.1 412341 D 592205 CDS YP_003057211.1 254779106 8207721 413230..413544 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 413544 8207721 HELPY_0420 Helicobacter pylori B38 hypothetical protein YP_003057211.1 413230 D 592205 CDS YP_003057212.1 254779107 8207722 413522..414289 1 NC_012973.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 414289 fliA 8207722 fliA Helicobacter pylori B38 flagellar biosynthesis sigma factor YP_003057212.1 413522 D 592205 CDS YP_003057213.1 254779108 8208532 414282..415346 1 NC_012973.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 415346 fliM 8208532 fliM Helicobacter pylori B38 flagellar motor switch protein FliM YP_003057213.1 414282 D 592205 CDS YP_003057214.1 254779109 8208540 415350..416213 1 NC_012973.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY 416213 fliY 8208540 fliY Helicobacter pylori B38 flagellar motor switch protein FliY YP_003057214.1 415350 D 592205 CDS YP_003057215.1 254779110 8208546 416242..416778 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 416778 8208546 HELPY_0424 Helicobacter pylori B38 hypothetical protein YP_003057215.1 416242 D 592205 CDS YP_003057216.1 254779111 8207723 416775..417272 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 417272 8207723 HELPY_0425 Helicobacter pylori B38 hypothetical protein YP_003057216.1 416775 D 592205 CDS YP_003057217.1 254779112 8207724 complement(417292..417744) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16369017, 15699202, 15221763, 12890020, 12748264, 12421315, 11796589; Product type r : regulator; ferric uptake regulation protein 417744 fur 8207724 fur Helicobacter pylori B38 ferric uptake regulation protein YP_003057217.1 417292 R 592205 CDS YP_003057218.1 254779113 8208569 complement(417904..419079) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15037234, 15037233; Product type pe : enzyme; recombination factor protein RarA 419079 8208569 HELPY_0427 Helicobacter pylori B38 recombination factor protein RarA YP_003057218.1 417904 R 592205 CDS YP_003057219.1 254779114 8207725 complement(419076..419447) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1988958, 2305262; Product type pr : regulator; transcriptional regulator, MerR family 419447 8207725 HELPY_0428 Helicobacter pylori B38 transcriptional regulator, MerR family YP_003057219.1 419076 R 592205 CDS YP_003057220.1 254779115 8207726 complement(419457..420323) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10894735, 16585746, 16533811, 16487673, 15763707, 14984054, 12369934; Product type f : factor; Chaperone protein DnaJ 420323 dnaJ 8207726 dnaJ Helicobacter pylori B38 Chaperone protein DnaJ YP_003057220.1 419457 R 592205 CDS YP_003057221.1 254779116 8208466 420491..421741 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 421741 8208466 HELPY_0430 Helicobacter pylori B38 hypothetical protein YP_003057221.1 420491 D 592205 CDS YP_003057222.1 254779117 8207727 complement(421859..422695) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 422695 8207727 HELPY_0431 Helicobacter pylori B38 hypothetical protein YP_003057222.1 421859 R 592205 CDS YP_003057223.1 254779118 8207728 complement(422735..422896) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 422896 8207728 HELPY_0432 Helicobacter pylori B38 hypothetical protein YP_003057223.1 422735 R 592205 CDS YP_003057224.1 254779119 8207729 complement(422950..423846) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10966457; Product type pr : regulator; two-component response regulator 423846 8207729 HELPY_0433 Helicobacter pylori B38 two-component response regulator YP_003057224.1 422950 R 592205 CDS YP_003057225.1 254779120 8207730 complement(423868..425088) 1 NC_012973.1 [Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/ (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT); 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS) (MECDP-synthase)]; bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein 425088 ispDF 8207730 ispDF Helicobacter pylori B38 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein YP_003057225.1 423868 R 592205 CDS YP_003057226.1 254779121 8208717 complement(425110..426540) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15547264, 12065478, 16585775, 16369036, 16177372, 16085809; Product type pe : enzyme; serine protease, peptidase S1C HrtA/DegP2/Q/S family 426540 8208717 HELPY_0435 Helicobacter pylori B38 serine protease, peptidase S1C HrtA/DegP2/Q/S family YP_003057226.1 425110 R 592205 CDS YP_003057227.1 254779122 8207731 complement(426585..428027) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; transporter; amino-acid transporter, AAT family; membrane protein 428027 8207731 HELPY_0436 Helicobacter pylori B38 transporter; amino-acid transporter, AAT family; membrane protein YP_003057227.1 426585 R 592205 CDS YP_003057228.1 254779123 8207732 complement(428241..428780) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16514141, 10629182, 8576035; Product type e : enzyme; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 428780 pgsA 8207732 pgsA Helicobacter pylori B38 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_003057228.1 428241 R 592205 CDS YP_003057229.1 254779124 8208857 complement(428777..429388) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 429388 8208857 HELPY_0438 Helicobacter pylori B38 hypothetical protein YP_003057229.1 428777 R 592205 CDS YP_003057230.1 254779125 8207733 complement(429398..430186) 1 NC_012973.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 430186 8207733 HELPY_0439 Helicobacter pylori B38 7-alpha-hydroxysteroid dehydrogenase YP_003057230.1 429398 R 592205 CDS YP_003057231.1 254779126 8207734 complement(430183..431085) 1 NC_012973.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 431085 dapA 8207734 dapA Helicobacter pylori B38 dihydrodipicolinate synthase YP_003057231.1 430183 R 592205 CDS YP_003057232.1 254779127 8208448 complement(431100..432434) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; zinc protease 432434 8208448 HELPY_0441 Helicobacter pylori B38 zinc protease YP_003057232.1 431100 R 592205 CDS YP_003057233.1 254779128 8207735 complement(432431..433486) 1 NC_012973.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 433486 pyrD 8207735 pyrD Helicobacter pylori B38 dihydroorotate dehydrogenase 2 YP_003057233.1 432431 R 592205 CDS YP_003057234.1 254779129 8208894 complement(433523..435550) 1 NC_012973.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 435550 ppk 8208894 ppk Helicobacter pylori B38 polyphosphate kinase YP_003057234.1 433523 R 592205 CDS YP_003057235.1 254779130 8208343 complement(435987..437246) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9837717, 8336674, 3323532; Product type e : enzyme; type I restriction/modification specificity protein 437246 hsdS1 8208343 hsdS1 Helicobacter pylori B38 type I restriction/modification specificity protein YP_003057235.1 435987 R 592205 CDS YP_003057236.1 254779131 8208689 complement(437239..438870) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16614449, 16368872, 16207918, 15699185, 15475385, 3323532; Product type e : enzyme; type I restriction enzyme M protein 438870 hsdM1 8208689 hsdM1 Helicobacter pylori B38 type I restriction enzyme M protein YP_003057236.1 437239 R 592205 CDS YP_003057237.1 254779132 8207737 complement(442070..443965) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 443965 8207737 HELPY_0448 Helicobacter pylori B38 hypothetical protein YP_003057237.1 442070 R 592205 CDS YP_003057238.1 254779133 8207738 complement(443991..444758) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 444758 8207738 HELPY_0449 Helicobacter pylori B38 hypothetical protein YP_003057238.1 443991 R 592205 CDS YP_003057239.1 254779134 8207739 complement(444768..445082) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 445082 8207739 HELPY_0450 Helicobacter pylori B38 hypothetical protein YP_003057239.1 444768 R 592205 CDS YP_003057240.1 254779135 8207740 complement(445084..446571) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 446571 8207740 HELPY_0451 Helicobacter pylori B38 hypothetical protein YP_003057240.1 445084 R 592205 CDS YP_003057241.1 254779136 8207741 complement(446583..447071) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 447071 8207741 HELPY_0452 Helicobacter pylori B38 hypothetical protein YP_003057241.1 446583 R 592205 CDS YP_003057242.1 254779137 8207742 complement(447056..448792) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16391147, 11741842, 7674922, 7798200; Product type e : enzyme; Oligoendopeptidase F 448792 pepF 8207742 pepF Helicobacter pylori B38 Oligoendopeptidase F YP_003057242.1 447056 R 592205 CDS YP_003057243.1 254779138 8208846 complement(448871..450139) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14604015, 10742217, 10092637, 9537504; Product type t : transporter; sodium/hydrogen exchanger 450139 8208846 HELPY_0455 Helicobacter pylori B38 sodium/hydrogen exchanger YP_003057243.1 448871 R 592205 CDS YP_003057244.1 254779139 8207743 complement(450468..451028) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 6322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HorE 451028 horE 8207743 horE Helicobacter pylori B38 outer membrane protein HorE YP_003057244.1 450468 R 592205 CDS YP_003057245.1 254779140 8208669 451254..451994 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16385130, 11421278, 10446207; Product type t : transporter; ABC transporter substrate-binding protein 451994 modA 8208669 modA Helicobacter pylori B38 ABC transporter substrate-binding protein YP_003057245.1 451254 D 592205 CDS YP_003057246.1 254779141 8208769 452016..452690 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16452441, 16385130, 15489438, 11421278; Product type t : transporter; ABC transporter permease; molybdate transporter; membrane protein 452690 modB 8208769 modB Helicobacter pylori B38 ABC transporter permease; molybdate transporter; membrane protein YP_003057246.1 452016 D 592205 CDS YP_003057247.1 254779142 8208770 452687..453484 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14756792, 11421278, 7665460, 9325422; Product type t : transporter; ABC transporter ATP-binding protein; molybdate transporter 453484 modC 8208770 modC Helicobacter pylori B38 ABC transporter ATP-binding protein; molybdate transporter YP_003057247.1 452687 D 592205 CDS YP_003057248.1 254779143 8208771 complement(453601..454992) 1 NC_012973.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 454992 gltX 8208771 gltX Helicobacter pylori B38 glutamyl-tRNA synthetase YP_003057248.1 453601 R 592205 CDS YP_003057249.1 254779144 8208591 455109..456209 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16220040, 16173498, 15918181, 12454856, 11211867, 9252185; Product type m : membrane component; outer membrane protein HopJ 456209 hopJ 8208591 hopJ Helicobacter pylori B38 outer membrane protein HopJ YP_003057249.1 455109 D 592205 CDS YP_003057250.1 254779145 8208657 456218..457855 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11133936, 11226310; Product type e : enzyme; type II adenine methyltransferase 457855 hpyAVIIM 8208657 hpyAVIIM Helicobacter pylori B38 type II adenine methyltransferase YP_003057250.1 456218 D 592205 CDS YP_003057251.1 254779146 8208684 457821..458669 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310, 11133936; Product type pe : enzyme; non-functional type II restriction endonuclease 458669 8208684 HELPY_0463 Helicobacter pylori B38 non-functional type II restriction endonuclease YP_003057251.1 457821 D 592205 CDS YP_003057252.1 254779147 8207744 458715..460514 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15297874, 15000390, 11683274, 9622352, 7737996; Product type f : factor; GTP-binding elongation factor protein, TypA subfamily 460514 typA 8207744 typA Helicobacter pylori B38 GTP-binding elongation factor protein, TypA subfamily YP_003057252.1 458715 D 592205 CDS YP_003057253.1 254779148 8209067 460518..461564 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11226310, 11133936; Product type e : enzyme; type II cytosine specific DNA methyltransferase 461564 hpy99XIM 8209067 hpy99XIM Helicobacter pylori B38 type II cytosine specific DNA methyltransferase YP_003057253.1 460518 D 592205 CDS YP_003057254.1 254779149 8208679 461566..462318 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310; Product type pe : enzyme; non-functional type II restriction endonuclease 462318 8208679 HELPY_0466 Helicobacter pylori B38 non-functional type II restriction endonuclease YP_003057254.1 461566 D 592205 CDS YP_003057255.1 254779150 8207745 complement(462525..463469) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16885452, 16879643, 16416177, 16298744, 16008611, 8955320, 2045782; Product type pe : enzyme; catalase 463469 8207745 HELPY_0468 Helicobacter pylori B38 catalase YP_003057255.1 462525 R 592205 CDS YP_003057256.1 254779151 8207746 463756..465342 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HofC 465342 hofC 8207746 hofC Helicobacter pylori B38 outer membrane protein HofC YP_003057256.1 463756 D 592205 CDS YP_003057257.1 254779152 8208638 465414..466826 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HofD 466826 hofD 8208638 hofD Helicobacter pylori B38 outer membrane protein HofD YP_003057257.1 465414 D 592205 CDS YP_003057258.1 254779153 8207747 468877..469035 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 469035 8207747 HELPY_0472 Helicobacter pylori B38 hypothetical protein YP_003057258.1 468877 D 592205 CDS YP_003057259.1 254779154 8207748 469204..469374 1 NC_012973.1 Evidence 6 : Doubtful CDS; hypothetical protein 469374 8207748 HELPY_0473 Helicobacter pylori B38 hypothetical protein YP_003057259.1 469204 D 592205 CDS YP_003057260.1 254779155 8207749 complement(470089..470820) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 470820 8207749 HELPY_0474 Helicobacter pylori B38 hypothetical protein YP_003057260.1 470089 R 592205 CDS YP_003057261.1 254779156 8207750 470953..471426 1 NC_012973.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 471426 ruvC 8207750 ruvC Helicobacter pylori B38 Holliday junction resolvase YP_003057261.1 470953 D 592205 CDS YP_003057262.1 254779157 8208998 complement(471427..473802) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12704139, 12165031, 11886560, 11466300, 16914236, 11953376, 10217784; Product type m : membrane component; Iron-regulated outer membrane protein 473802 frpB1 8208998 frpB1 Helicobacter pylori B38 Iron-regulated outer membrane protein YP_003057262.1 471427 R 592205 CDS YP_003057263.1 254779158 8208557 474126..475643 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16885452, 16879643, 16416177, 16298744, 16008611, 8955320, 2045782; Product type e : enzyme; catalase 475643 katA 8208557 katA Helicobacter pylori B38 catalase YP_003057263.1 474126 D 592205 CDS YP_003057264.1 254779159 8208721 475788..476663 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 476663 8208721 HELPY_0478 Helicobacter pylori B38 hypothetical protein YP_003057264.1 475788 D 592205 CDS YP_003057265.1 254779160 8207751 476748..476963 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 476963 8207751 HELPY_0479 Helicobacter pylori B38 hypothetical protein YP_003057265.1 476748 D 592205 CDS YP_003057266.1 254779161 8207752 complement(477016..477345) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9300819, 2155230; Product type pt : transporter; alkylphosphonate uptake protein PhnA 477345 8207752 HELPY_0480 Helicobacter pylori B38 alkylphosphonate uptake protein PhnA YP_003057266.1 477016 R 592205 CDS YP_003057267.1 254779162 8207753 477698..478432 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12000771, 11557141, 11016943, 2995360; Product type e : enzyme; CDP-diacylglycerol pyrophosphatase 478432 cdh 8207753 cdh Helicobacter pylori B38 CDP-diacylglycerol pyrophosphatase YP_003057267.1 477698 D 592205 CDS YP_003057268.1 254779163 8208416 478641..480797 1 NC_012973.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 480797 flgE 8208416 flgE Helicobacter pylori B38 flagellar hook protein FlgE YP_003057268.1 478641 D 592205 CDS YP_003057269.1 254779164 8208519 480856..481209 1 NC_012973.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 481209 hypA 8208519 hypA Helicobacter pylori B38 hydrogenase nickel incorporation protein YP_003057269.1 480856 D 592205 CDS YP_003057270.1 254779165 8208699 481216..481677 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 481677 8208699 HELPY_0484 Helicobacter pylori B38 hypothetical protein YP_003057270.1 481216 D 592205 CDS YP_003057271.1 254779166 8207754 481677..482759 1 NC_012973.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase 482759 lpxB 8207754 lpxB Helicobacter pylori B38 ipid-A-disaccharide synthase YP_003057271.1 481677 D 592205 CDS YP_003057272.1 254779167 8208739 482800..483294 1 NC_012973.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 483294 greA 8208739 greA Helicobacter pylori B38 transcription elongation factor GreA YP_003057272.1 482800 D 592205 CDS YP_003057273.1 254779168 8208603 483284..483721 1 NC_012973.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 483721 dut 8208603 dut Helicobacter pylori B38 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_003057273.1 483284 D 592205 CDS YP_003057274.1 254779169 8208478 483718..484374 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 484374 8208478 HELPY_0488 Helicobacter pylori B38 hypothetical protein YP_003057274.1 483718 D 592205 CDS YP_003057275.1 254779170 8207755 484379..485980 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14769936, 16513394; Product type f : factor; Plasminogen-binding protein PgbB 485980 pgbB 8207755 pgbB Helicobacter pylori B38 Plasminogen-binding protein PgbB YP_003057275.1 484379 D 592205 CDS YP_003057276.1 254779171 8208852 485985..486656 1 NC_012973.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 486656 8208852 HELPY_0490 Helicobacter pylori B38 pantothenate kinase YP_003057276.1 485985 D 592205 CDS YP_003057277.1 254779172 8207756 486656..487387 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 487387 8207756 HELPY_0491 Helicobacter pylori B38 hypothetical protein YP_003057277.1 486656 D 592205 CDS YP_003057278.1 254779173 8207757 487377..487898 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12101286, 11751812; Product type e : enzyme; D,D-heptose 1,7-bisphosphate phosphatase 487898 gmhB 8207757 gmhB Helicobacter pylori B38 D,D-heptose 1,7-bisphosphate phosphatase YP_003057278.1 487377 D 592205 CDS YP_003057279.1 254779174 8208598 487907..488899 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15823050, 11751812, 11496013, 11349030, 9353016, 9119477; Product type e : enzyme; ADP-L-glycero-D-manno-heptose-6-epimerase 488899 rfaD 8208598 rfaD Helicobacter pylori B38 ADP-L-glycero-D-manno-heptose-6-epimerase YP_003057279.1 487907 D 592205 CDS YP_003057280.1 254779175 8208911 488896..490281 1 NC_012973.1 [Includes: D-beta-D-heptose 7-phosphate kinase (D-beta-D-heptose 7-phosphotransferase); D-beta-D-heptose 1-phosphate adenosyltransferase ]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12803486, 12441667, 11496013, 10629197, 8755886; Product type e : enzyme; Bifunctional protein HldE 490281 rfaE 8208911 rfaE Helicobacter pylori B38 Bifunctional protein HldE YP_003057280.1 488896 D 592205 CDS YP_003057281.1 254779176 8208912 490274..490852 1 NC_012973.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 490852 gmhA 8208912 gmhA Helicobacter pylori B38 phosphoheptose isomerase YP_003057281.1 490274 D 592205 CDS YP_003057282.1 254779177 8208597 complement(490855..491949) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 491949 8208597 HELPY_0496 Helicobacter pylori B38 hypothetical protein YP_003057282.1 490855 R 592205 CDS YP_003057283.1 254779178 8207760 493565..493684 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 493684 8207760 HELPY_0499 Helicobacter pylori B38 hypothetical protein YP_003057283.1 493565 D 592205 CDS YP_003057284.1 254779179 8207761 complement(493691..494668) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1979163, 1039060, 12923093, 2904262; Product type e : enzyme; guanosine 5'-monophosphate oxidoreductase 494668 guaC 8207761 guaC Helicobacter pylori B38 guanosine 5'-monophosphate oxidoreductase YP_003057284.1 493691 R 592205 CDS YP_003057285.1 254779180 8208611 494866..496467 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1051871, 9593292; Product type t : transporter; ABC transporter ATP-binding protein 496467 8208611 HELPY_0501 Helicobacter pylori B38 ABC transporter ATP-binding protein YP_003057285.1 494866 D 592205 CDS YP_003057286.1 254779181 8207764 complement(497440..498126) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 498126 8207764 HELPY_0504 Helicobacter pylori B38 hypothetical protein YP_003057286.1 497440 R 592205 CDS YP_003057287.1 254779182 8207767 499895..500512 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12105196, 15699185, 2784505; Product type e : enzyme; type I R-M system specificity subunit 500512 hsdS2 8207767 hsdS2 Helicobacter pylori B38 type I R-M system specificity subunit YP_003057287.1 499895 D 592205 CDS YP_003057288.1 254779183 8207769 503595..504374 1 NC_012973.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 504374 thiM 8207769 thiM Helicobacter pylori B38 hydroxyethylthiazole kinase YP_003057288.1 503595 D 592205 CDS YP_003057289.1 254779184 8209032 504371..505180 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15292217, 12794638, 11839308, 10382260, 10075431, 9244280; Product type e : enzyme; phosphomethylpyrimidine kinase (HMP-phosphate kinase) (HMP-P kinase) 505180 thiD 8209032 thiD Helicobacter pylori B38 phosphomethylpyrimidine kinase (HMP-phosphate kinase) (HMP-P kinase) YP_003057289.1 504371 D 592205 CDS YP_003057290.1 254779185 8209030 505173..505835 1 NC_012973.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 505835 thiE 8209030 thiE Helicobacter pylori B38 thiamine-phosphate pyrophosphorylase YP_003057290.1 505173 D 592205 CDS YP_003057291.1 254779186 8209031 complement(505944..506681) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 506681 8209031 HELPY_0513 Helicobacter pylori B38 hypothetical protein YP_003057291.1 505944 R 592205 CDS YP_003057292.1 254779187 8207770 complement(506681..507958) 1 NC_012973.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 507958 dfp 8207770 dfp Helicobacter pylori B38 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_003057292.1 506681 R 592205 CDS YP_003057293.1 254779188 8208460 complement(507955..508956) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16286454, 16077121, 15956417, 15322055, 15060026, 14562386, 10954725; Product type e : enzyme; UDP-GlcNAc C6 dehydratase/C5 epimerase 508956 flaA1 8208460 flaA1 Helicobacter pylori B38 UDP-GlcNAc C6 dehydratase/C5 epimerase YP_003057293.1 507955 R 592205 CDS YP_003057294.1 254779189 8208512 complement(508960..510723) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185, 8899706; Product type m : membrane component; outer membrane protein P1 510723 ompP1 8208512 ompP1 Helicobacter pylori B38 outer membrane protein P1 YP_003057294.1 508960 R 592205 CDS YP_003057295.1 254779190 8208827 complement(510720..511337) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 511337 8208827 HELPY_0517 Helicobacter pylori B38 hypothetical protein YP_003057295.1 510720 R 592205 CDS YP_003057296.1 254779191 8207771 complement(511357..511968) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 511968 8207771 HELPY_0518 Helicobacter pylori B38 hypothetical protein YP_003057296.1 511357 R 592205 CDS YP_003057297.1 254779192 8208342 complement(512571..512855) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15255779; Product type r : regulator; Histone-like DNA-binding protein HU 512855 hup 8208342 hup Helicobacter pylori B38 Histone-like DNA-binding protein HU YP_003057297.1 512571 R 592205 CDS YP_003057298.1 254779193 8208694 complement(513007..514392) 1 NC_012973.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 514392 engA 8208694 engA Helicobacter pylori B38 GTP-binding protein EngA YP_003057298.1 513007 R 592205 CDS YP_003057299.1 254779194 8207773 514469..515353 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 515353 8207773 HELPY_0521 Helicobacter pylori B38 hypothetical protein YP_003057299.1 514469 D 592205 CDS YP_003057300.1 254779195 8207774 515440..516228 1 NC_012973.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 516228 speE 8207774 speE Helicobacter pylori B38 spermidine synthase YP_003057300.1 515440 D 592205 CDS YP_003057301.1 254779196 8209017 516230..516820 1 NC_012973.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 516820 coaE 8209017 coaE Helicobacter pylori B38 dephospho-CoA kinase YP_003057301.1 516230 D 592205 CDS YP_003057302.1 254779197 8208430 516880..518241 1 NC_012973.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 518241 gatA 8208430 gatA Helicobacter pylori B38 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_003057302.1 516880 D 592205 CDS YP_003057303.1 254779198 8208577 518251..519696 1 NC_012973.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 519696 guaB 8208577 guaB Helicobacter pylori B38 inosine 5'-monophosphate dehydrogenase YP_003057303.1 518251 D 592205 CDS YP_003057304.1 254779199 8208610 519818..520498 1 NC_012973.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 520498 atpB 8208610 atpB Helicobacter pylori B38 F0F1 ATP synthase subunit A YP_003057304.1 519818 D 592205 CDS YP_003057305.1 254779200 8208394 520820..521068 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2470643; Product type r : regulator; Nucleotide binding protein 521068 8208394 HELPY_0528 Helicobacter pylori B38 Nucleotide binding protein YP_003057305.1 520820 D 592205 CDS YP_003057306.1 254779201 8207775 complement(521298..522119) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyltransferase, family 25 522119 8207775 HELPY_0529 Helicobacter pylori B38 glycosyltransferase, family 25 YP_003057306.1 521298 R 592205 CDS YP_003057307.1 254779202 8207776 complement(522476..523411) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16354674, 16213196, 15965489, 11222594, 10671551; Product type e : enzyme; thioredoxin reductase (TRXR) (TR) 523411 trxR1 8207776 trxR1 Helicobacter pylori B38 thioredoxin reductase (TRXR) (TR) YP_003057307.1 522476 R 592205 CDS YP_003057308.1 254779203 8209063 complement(523416..523736) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16354674, 16213196, 15965489, 11222594, 10671551; Product type c : carrier; thioredoxin 1 523736 trx1 8209063 trx1 Helicobacter pylori B38 thioredoxin 1 YP_003057308.1 523416 R 592205 CDS YP_003057309.1 254779204 8209060 complement(523825..524169) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 524169 8209060 HELPY_0533 Helicobacter pylori B38 hypothetical protein YP_003057309.1 523825 R 592205 CDS YP_003057310.1 254779205 8207777 complement(524170..525435) 1 NC_012973.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 525435 hom 8207777 hom Helicobacter pylori B38 homoserine dehydrogenase YP_003057310.1 524170 R 592205 CDS YP_003057311.1 254779206 8208645 complement(525446..527230) 1 NC_012973.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 527230 uvrC 8208645 uvrC Helicobacter pylori B38 excinuclease ABC subunit C YP_003057311.1 525446 R 592205 CDS YP_003057312.1 254779207 8209085 complement(527231..527692) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 527692 8209085 HELPY_0536 Helicobacter pylori B38 hypothetical protein YP_003057312.1 527231 R 592205 CDS YP_003057313.1 254779208 8207778 complement(527875..528516) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2691838, 2515417, 7592481; Product type e : enzyme; ABC transporter ATP-binding protein; osmoprotection ABC transporter involved in glycine/betaine/L-proline transport 528516 8207778 HELPY_0538 Helicobacter pylori B38 ABC transporter ATP-binding protein; osmoprotection ABC transporter involved in glycine/betaine/L-proline transport YP_003057313.1 527875 R 592205 CDS YP_003057314.1 254779209 8207779 complement(528520..530190) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10216873; Product type t : transporter; ABC transporter permease; betaine/proline/choline transporter; membrane protein 530190 8207779 HELPY_0539 Helicobacter pylori B38 ABC transporter permease; betaine/proline/choline transporter; membrane protein YP_003057314.1 528520 R 592205 CDS YP_003057315.1 254779210 8207780 complement(530250..530696) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 530696 8207780 HELPY_0540 Helicobacter pylori B38 hypothetical protein YP_003057315.1 530250 R 592205 CDS YP_003057316.1 254779211 8207781 complement(530693..531466) 1 NC_012973.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 531466 motB 8207781 motB Helicobacter pylori B38 flagellar motor protein MotB YP_003057316.1 530693 R 592205 CDS YP_003057317.1 254779212 8208776 complement(531469..532242) 1 NC_012973.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 532242 motA 8208776 motA Helicobacter pylori B38 flagellar motor protein MotA YP_003057317.1 531469 R 592205 CDS YP_003057318.1 254779213 8208775 complement(532258..533025) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16388576, 15896804, 12234097, 11290749, 11463785, 11438688, 11713534; Product type e : enzyme; molybdopterin/thiamine biosynthesis activator 533025 moeB 8208775 moeB Helicobacter pylori B38 molybdopterin/thiamine biosynthesis activator YP_003057318.1 532258 R 592205 CDS YP_003057319.1 254779214 8208773 complement(533026..533643) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 533643 8208773 HELPY_0544 Helicobacter pylori B38 hydrolase YP_003057319.1 533026 R 592205 CDS YP_003057320.1 254779215 8207782 533775..534785 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 534785 8207782 HELPY_0545 Helicobacter pylori B38 hypothetical protein YP_003057320.1 533775 D 592205 CDS YP_003057321.1 254779216 8207783 535147..535473 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 535473 8207783 HELPY_0546 Helicobacter pylori B38 hypothetical protein YP_003057321.1 535147 D 592205 CDS YP_003057322.1 254779217 8207784 535452..536054 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; N-6 adenine methyltransferase 536054 8207784 HELPY_0547 Helicobacter pylori B38 N-6 adenine methyltransferase YP_003057322.1 535452 D 592205 CDS YP_003057323.1 254779218 8207785 536069..536620 1 NC_012973.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 536620 fliL 8207785 fliL Helicobacter pylori B38 flagellar basal body-associated protein FliL YP_003057323.1 536069 D 592205 CDS YP_003057324.1 254779219 8208539 536627..536983 1 NC_012973.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 536983 acpS 8208539 acpS Helicobacter pylori B38 4'-phosphopantetheinyl transferase YP_003057324.1 536627 D 592205 CDS YP_003057325.1 254779220 8207788 complement(539586..540206) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 540206 8207788 HELPY_0553 Helicobacter pylori B38 hydrolase YP_003057325.1 539586 R 592205 CDS YP_003057326.1 254779221 8207789 540288..541142 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817494; Product type pe : enzyme; glycosyl transferase, family 25; LPS biosynthesis protein 541142 8207789 HELPY_0554 Helicobacter pylori B38 glycosyl transferase, family 25; LPS biosynthesis protein YP_003057326.1 540288 D 592205 CDS YP_003057327.1 254779222 8207790 541309..542343 1 NC_012973.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 542343 ribBA 8207790 ribBA Helicobacter pylori B38 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein YP_003057327.1 541309 D 592205 CDS YP_003057328.1 254779223 8208918 542430..543269 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; Product type pm : membrane component; hypothetical protein 543269 8208918 HELPY_0557 Helicobacter pylori B38 hypothetical protein YP_003057328.1 542430 D 592205 CDS YP_003057329.1 254779224 8207791 543358..543936 1 NC_012973.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 543936 ribA 8207791 ribA Helicobacter pylori B38 GTP cyclohydrolase II YP_003057329.1 543358 D 592205 CDS YP_003057330.1 254779225 8208917 544013..544234 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15709772, 12372836, 8514782; Product type e : enzyme; molybdopterin-converting factor subunit 1 544234 moaD 8208917 moaD Helicobacter pylori B38 molybdopterin-converting factor subunit 1 YP_003057330.1 544013 D 592205 CDS YP_003057331.1 254779226 8208764 544235..544672 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12372836, 8514782; Product type e : enzyme; MPT synthase subunit 2 544672 moaE 8208764 moaE Helicobacter pylori B38 MPT synthase subunit 2 YP_003057331.1 544235 D 592205 CDS YP_003057332.1 254779227 8208765 544685..545215 1 NC_012973.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 545215 mogA 8208765 mogA Helicobacter pylori B38 molybdenum cofactor biosynthesis protein MogA YP_003057332.1 544685 D 592205 CDS YP_003057333.1 254779228 8208774 545225..545701 1 NC_012973.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 545701 moaC 8208774 moaC Helicobacter pylori B38 molybdenum cofactor biosynthesis protein MoaC YP_003057333.1 545225 D 592205 CDS YP_003057334.1 254779229 8208763 545820..546602 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16428735, 16041003, 15849827, 12819067, 11710844, 9287032, 7592366; Product type lp : lipoprotein; Neuraminyllactose-binding hemagglutinin HpaA 546602 hpaA 8208763 hpaA Helicobacter pylori B38 Neuraminyllactose-binding hemagglutinin HpaA YP_003057334.1 545820 D 592205 CDS YP_003057335.1 254779230 8208674 546631..547467 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16181353, 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HorG 547467 horG 8208674 horG Helicobacter pylori B38 outer membrane protein HorG YP_003057335.1 546631 D 592205 CDS YP_003057336.1 254779231 8208671 547579..548934 1 NC_012973.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 548934 tig 8208671 tig Helicobacter pylori B38 trigger factor YP_003057336.1 547579 D 592205 CDS YP_003057337.1 254779232 8209037 548952..549542 1 NC_012973.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 549542 clpP 8209037 clpP Helicobacter pylori B38 ATP-dependent Clp protease proteolytic subunit YP_003057337.1 548952 D 592205 CDS YP_003057338.1 254779233 8208427 549547..550071 1 NC_012973.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 550071 def 8208427 def Helicobacter pylori B38 peptide deformylase YP_003057338.1 549547 D 592205 CDS YP_003057339.1 254779234 8208457 550077..551597 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Mg chelatase-related protein; ComM protein 551597 8208457 HELPY_0568 Helicobacter pylori B38 Mg chelatase-related protein; ComM protein YP_003057339.1 550077 D 592205 CDS YP_003057340.1 254779235 8207792 551622..553682 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10417643, 10577484, 9789554, 8550601, 16835223, 16491024, 16388822; Product type t : transporter; Cadmium, zinc and cobalt-transporting ATPase 553682 cadA 8207792 cadA Helicobacter pylori B38 Cadmium, zinc and cobalt-transporting ATPase YP_003057340.1 551622 D 592205 CDS YP_003057341.1 254779236 8208411 complement(554109..555338) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 555338 8208411 HELPY_0571 Helicobacter pylori B38 transposase, OrfB, ISHp609 YP_003057341.1 554109 R 592205 CDS YP_003057342.1 254779237 8207793 complement(555325..555957) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 555957 8207793 HELPY_0572 Helicobacter pylori B38 Serine recombinase-transposase, OrfA, ISHp609 YP_003057342.1 555325 R 592205 CDS YP_003057343.1 254779238 8207794 complement(555954..556139) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 556139 8207794 HELPY_0573 Helicobacter pylori B38 hypothetical protein YP_003057343.1 555954 R 592205 CDS YP_003057344.1 254779239 8207795 complement(556141..556398) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 556398 8207795 HELPY_0574 Helicobacter pylori B38 hypothetical protein YP_003057344.1 556141 R 592205 CDS YP_003057345.1 254779240 8207797 complement(557677..559176) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HofF 559176 hofF 8207797 hofF Helicobacter pylori B38 outer membrane protein HofF YP_003057345.1 557677 R 592205 CDS YP_003057346.1 254779241 8208641 complement(559456..560688) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16585747, 12823819, 12198129, 10783239, 10783239; Product type t : transporter; ABC transporter permease; lipoprotein release system transmembrane protein LolC; membrane protein 560688 lolC 8208641 lolC Helicobacter pylori B38 ABC transporter permease; lipoprotein release system transmembrane protein LolC; membrane protein YP_003057346.1 559456 R 592205 CDS YP_003057347.1 254779242 8208734 complement(560678..563275) 1 NC_012973.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 563275 secA 8208734 secA Helicobacter pylori B38 preprotein translocase subunit SecA YP_003057347.1 560678 R 592205 CDS YP_003057348.1 254779243 8209003 563423..563977 1 NC_012973.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 563977 lolA 8209003 lolA Helicobacter pylori B38 outer-membrane lipoprotein carrier protein YP_003057348.1 563423 D 592205 CDS YP_003057349.1 254779244 8208733 564471..564998 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 564998 8208733 HELPY_0581 Helicobacter pylori B38 hypothetical protein YP_003057349.1 564471 D 592205 CDS YP_003057350.1 254779245 8207798 complement(565005..566372) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185, 7534278; Product type m : membrane component; outermembrane protein HofE 566372 hofE 8207798 hofE Helicobacter pylori B38 outermembrane protein HofE YP_003057350.1 565005 R 592205 CDS YP_003057351.1 254779246 8208640 complement(566466..567755) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 567755 8208640 HELPY_0583 Helicobacter pylori B38 hypothetical protein YP_003057351.1 566466 R 592205 CDS YP_003057352.1 254779247 8207799 complement(568015..568284) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 568284 8207799 HELPY_0584 Helicobacter pylori B38 hypothetical protein YP_003057352.1 568015 R 592205 CDS YP_003057353.1 254779248 8207800 complement(568362..570920) 1 NC_012973.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 570920 acnB 8207800 acnB Helicobacter pylori B38 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_003057353.1 568362 R 592205 CDS YP_003057354.1 254779249 8208365 571051..571734 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 571734 8208365 HELPY_0586 Helicobacter pylori B38 hypothetical protein YP_003057354.1 571051 D 592205 CDS YP_003057355.1 254779250 8207801 571843..572565 1 NC_012973.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 572565 pyrH 8207801 pyrH Helicobacter pylori B38 uridylate kinase YP_003057355.1 571843 D 592205 CDS YP_003057356.1 254779251 8208898 572607..572831 1 NC_012973.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 572831 rpoZ 8208898 rpoZ Helicobacter pylori B38 DNA-directed RNA polymerase subunit omega YP_003057356.1 572607 D 592205 CDS YP_003057357.1 254779252 8208974 572818..575145 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16672627, 2005135, 9882669, 16467149, 16343907, 15853883; Product type e : enzyme; guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase /guanosine-3',5'-bis(diphosphate) synthetase II 575145 spoT 8208974 spoT Helicobacter pylori B38 guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase /guanosine-3',5'-bis(diphosphate) synthetase II YP_003057357.1 572818 D 592205 CDS YP_003057358.1 254779253 8209018 575169..576377 1 NC_012973.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 576377 tyrS 8209018 tyrS Helicobacter pylori B38 tyrosyl-tRNA synthetase YP_003057358.1 575169 D 592205 CDS YP_003057359.1 254779254 8209069 576394..577485 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 577485 8209069 HELPY_0591 Helicobacter pylori B38 oxidoreductase YP_003057359.1 576394 D 592205 CDS YP_003057360.1 254779255 8207802 577492..578838 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17085576; Product type e : enzyme; N-acetylmuramoyl-L-alanine amidase 578838 amiA 8207802 amiA Helicobacter pylori B38 N-acetylmuramoyl-L-alanine amidase YP_003057360.1 577492 D 592205 CDS YP_003057361.1 254779256 8208374 578857..579594 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 579594 8208374 HELPY_0593 Helicobacter pylori B38 hypothetical protein YP_003057361.1 578857 D 592205 CDS YP_003057362.1 254779257 8207803 complement(579681..580757) 1 NC_012973.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 580757 flhB 8207803 flhB Helicobacter pylori B38 flagellar biosynthesis protein FlhB YP_003057362.1 579681 R 592205 CDS YP_003057363.1 254779258 8208530 complement(580750..581355) 1 NC_012973.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 581355 mobA 8208530 mobA Helicobacter pylori B38 molybdopterin-guanine dinucleotide biosynthesis protein A YP_003057363.1 580750 R 592205 CDS YP_003057364.1 254779259 8208766 581440..582405 1 NC_012973.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 582405 moaA 8208766 moaA Helicobacter pylori B38 molybdenum cofactor biosynthesis protein A YP_003057364.1 581440 D 592205 CDS YP_003057365.1 254779260 8207805 583527..583835 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 583835 8207805 HELPY_0599 Helicobacter pylori B38 hypothetical protein YP_003057365.1 583527 D 592205 CDS YP_003057366.1 254779261 8207808 complement(585209..586090) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16820862; Product type pf : factor; signal recognition particule receptor FtsY 586090 8207808 HELPY_0602 Helicobacter pylori B38 signal recognition particule receptor FtsY YP_003057366.1 585209 R 592205 CDS YP_003057367.1 254779262 8207809 complement(586097..586663) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 586663 8207809 HELPY_0603 Helicobacter pylori B38 hypothetical protein YP_003057367.1 586097 R 592205 CDS YP_003057368.1 254779263 8207810 586824..587426 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 587426 8207810 HELPY_0604 Helicobacter pylori B38 hypothetical protein YP_003057368.1 586824 D 592205 CDS YP_003057369.1 254779264 8207811 587404..588915 1 NC_012973.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 588915 8207811 HELPY_0605 Helicobacter pylori B38 phosphodiesterase YP_003057369.1 587404 D 592205 CDS YP_003057370.1 254779265 8207812 complement(588916..590169) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16189122, 15716425, 14695443, 14679249; Product type t : transporter; multidrug efflux protein MatE; membrane protein 590169 8207812 HELPY_0606 Helicobacter pylori B38 multidrug efflux protein MatE; membrane protein YP_003057370.1 588916 R 592205 CDS YP_003057371.1 254779266 8207813 complement(590232..591545) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type m : membrane component; hypothetical protein 591545 8207813 HELPY_0607 Helicobacter pylori B38 hypothetical protein YP_003057371.1 590232 R 592205 CDS YP_003057372.1 254779267 8207814 complement(591671..592549) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11380987, 7987228; Product type pe : enzyme; carbon-nitrogen hydrolase 592549 8207814 HELPY_0608 Helicobacter pylori B38 carbon-nitrogen hydrolase YP_003057372.1 591671 R 592205 CDS YP_003057373.1 254779268 8207815 complement(592553..592699) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 592699 8207815 HELPY_0609 Helicobacter pylori B38 hypothetical protein YP_003057373.1 592553 R 592205 CDS YP_003057374.1 254779269 8207816 complement(592725..593384) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12234097, 11713534; Product type pf : factor; molybdenum biosynthesis cofactor, MoeB/ThiF family 593384 8207816 HELPY_0610 Helicobacter pylori B38 molybdenum biosynthesis cofactor, MoeB/ThiF family YP_003057374.1 592725 R 592205 CDS YP_003057375.1 254779270 8207817 complement(593438..593677) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 593677 8207817 HELPY_0611 Helicobacter pylori B38 hypothetical protein YP_003057375.1 593438 R 592205 CDS YP_003057376.1 254779271 8207818 complement(593664..594044) 1 NC_012973.1 flagellin specific chaperone; flagellar protein FliS 594044 fliS 8207818 fliS Helicobacter pylori B38 flagellar protein FliS YP_003057376.1 593664 R 592205 CDS YP_003057377.1 254779272 8208545 complement(594085..596142) 1 NC_012973.1 involved in flagellin assembly; flagellar capping protein 596142 fliD 8208545 fliD Helicobacter pylori B38 flagellar capping protein YP_003057377.1 594085 R 592205 CDS YP_003057378.1 254779273 8208533 complement(596159..596518) 1 NC_012973.1 possibly involved in flagella export; flagellar protein FlaG 596518 flaG 8208533 flaG Helicobacter pylori B38 flagellar protein FlaG YP_003057378.1 596159 R 592205 CDS YP_003057379.1 254779274 8208514 complement(596611..597813) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 597813 8208514 HELPY_0615 Helicobacter pylori B38 hypothetical protein YP_003057379.1 596611 R 592205 CDS YP_003057380.1 254779275 8207819 complement(597806..598612) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16416128, 14729705, 11430412; Product type t : transporter; ABC transporter permease 598612 8207819 HELPY_0616 Helicobacter pylori B38 ABC transporter permease YP_003057380.1 597806 R 592205 CDS YP_003057381.1 254779276 8207820 complement(598599..599270) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16416128, 14729705, 11430412, 9593292, 10518715, 3025556; Product type t : transporter; ABC transporter ATP-binding protein; cell division protein FtsE 599270 8207820 HELPY_0617 Helicobacter pylori B38 ABC transporter ATP-binding protein; cell division protein FtsE YP_003057381.1 598599 R 592205 CDS YP_003057382.1 254779277 8207821 complement(599267..600442) 1 NC_012973.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 600442 8207821 HELPY_0618 Helicobacter pylori B38 tRNA (guanine-N(7)-)-methyltransferase YP_003057382.1 599267 R 592205 CDS YP_003057383.1 254779278 8207822 complement(600453..601667) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 601667 8207822 HELPY_0619 Helicobacter pylori B38 hypothetical protein YP_003057383.1 600453 R 592205 CDS YP_003057384.1 254779279 8207823 complement(601669..602652) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15928344, 15078091, 14730022, 14659742, 14501142, 9814761, 9843401; Product type e : enzyme; Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) 602652 rluD2 8207823 rluD2 Helicobacter pylori B38 Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) YP_003057384.1 601669 R 592205 CDS YP_003057385.1 254779280 8207826 604013..605158 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15612918, 12596863, 11976312, 9922463, 962235, 7575501, 250943; Product type cp : cell process; Rod shape-determining protein RodA; membrane protein 605158 rodA 8207826 rodA Helicobacter pylori B38 Rod shape-determining protein RodA; membrane protein YP_003057385.1 604013 D 592205 CDS YP_003057386.1 254779281 8208346 complement(605224..606180) 1 NC_012973.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 606180 prs 8208346 prs Helicobacter pylori B38 ribose-phosphate pyrophosphokinase YP_003057386.1 605224 R 592205 CDS YP_003057387.1 254779282 8208879 complement(606245..606730) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12119013, 9164465, 1472710; Product type pe : enzyme; HIT family protein 606730 8208879 HELPY_0626 Helicobacter pylori B38 HIT family protein YP_003057387.1 606245 R 592205 CDS YP_003057388.1 254779283 8207827 complement(606740..608221) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15694856, 15694856, 8973200, 2668880; Product type e : enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; membrane protein 608221 murF 8207827 murF Helicobacter pylori B38 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; membrane protein YP_003057388.1 606740 R 592205 CDS YP_003057389.1 254779284 8208788 complement(608208..608933) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 608933 8208788 HELPY_0628 Helicobacter pylori B38 hypothetical protein YP_003057389.1 608208 R 592205 CDS YP_003057390.1 254779285 8207828 complement(608934..609983) 1 NC_012973.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 609983 ddl 8207828 ddl Helicobacter pylori B38 D-alanyl-alanine synthetase A YP_003057390.1 608934 R 592205 CDS YP_003057391.1 254779286 8208455 complement(610055..610531) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1309518, 2846511, 2846510; Product type e : enzyme; phosphatidylglycerophosphatase A 610531 pgpA 8208455 pgpA Helicobacter pylori B38 phosphatidylglycerophosphatase A YP_003057391.1 610055 R 592205 CDS YP_003057392.1 254779287 8208856 610679..611788 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8482384; Product type pe : enzyme; class V aminotransferase 611788 8208856 HELPY_0631 Helicobacter pylori B38 class V aminotransferase YP_003057392.1 610679 D 592205 CDS YP_003057393.1 254779288 8207829 611797..612258 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 692401, 9743633, 3886014; Product type pe : enzyme; nucleotide phosphoribosyl transferase 612258 8207829 HELPY_0632 Helicobacter pylori B38 nucleotide phosphoribosyl transferase YP_003057393.1 611797 D 592205 CDS YP_003057394.1 254779289 8207830 612260..613579 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 613579 8207830 HELPY_0633 Helicobacter pylori B38 hypothetical protein YP_003057394.1 612260 D 592205 CDS YP_003057395.1 254779290 8207833 615500..617218 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10768971; Product type pf : factor; LeoA protein 617218 8207833 HELPY_0636 Helicobacter pylori B38 LeoA protein YP_003057395.1 615500 D 592205 CDS YP_003057396.1 254779291 8207834 617323..617628 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 617628 8207834 HELPY_0637 Helicobacter pylori B38 hypothetical protein YP_003057396.1 617323 D 592205 CDS YP_003057397.1 254779292 8207835 617637..618704 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 618704 8207835 HELPY_0638 Helicobacter pylori B38 hypothetical protein YP_003057397.1 617637 D 592205 CDS YP_003057398.1 254779293 8207836 618740..619756 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16039592, 15124629; Product type e : enzyme; tRNA(Ile)-lysidine synthase 619756 tilS 8207836 tilS Helicobacter pylori B38 tRNA(Ile)-lysidine synthase YP_003057398.1 618740 D 592205 CDS YP_003057399.1 254779294 8209038 619849..620835 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 620835 8209038 HELPY_0640 Helicobacter pylori B38 transcriptional regulator YP_003057399.1 619849 D 592205 CDS YP_003057400.1 254779295 8207837 620832..621722 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type pm : membrane component; outer membrane protein 621722 8207837 HELPY_0641 Helicobacter pylori B38 outer membrane protein YP_003057400.1 620832 D 592205 CDS YP_003057401.1 254779296 8207838 621942..623909 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HopP 623909 hopP 8207838 hopP Helicobacter pylori B38 outer membrane protein HopP YP_003057401.1 621942 D 592205 CDS YP_003057402.1 254779297 8208663 complement(623984..625315) 1 NC_012973.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 625315 dcuA 8208663 dcuA Helicobacter pylori B38 anaerobic C4-dicarboxylate transporter YP_003057402.1 623984 R 592205 CDS YP_003057403.1 254779298 8208454 625444..626436 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2407723, 8898907; Product type e : enzyme; L-asparaginase 626436 ansB 8208454 ansB Helicobacter pylori B38 L-asparaginase YP_003057403.1 625444 D 592205 CDS YP_003057404.1 254779299 8208377 complement(626501..626920) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 626920 8208377 HELPY_0645 Helicobacter pylori B38 hypothetical protein YP_003057404.1 626501 R 592205 CDS YP_003057405.1 254779300 8207839 complement(627101..627562) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 627562 8207839 HELPY_0646 Helicobacter pylori B38 hypothetical protein YP_003057405.1 627101 R 592205 CDS YP_003057406.1 254779301 8207840 complement(627593..628078) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 628078 8207840 HELPY_0647 Helicobacter pylori B38 hypothetical protein YP_003057406.1 627593 R 592205 CDS YP_003057407.1 254779302 8207841 628279..628911 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; L-lysine exporter; membrane protein 628911 8207841 HELPY_0648 Helicobacter pylori B38 L-lysine exporter; membrane protein YP_003057407.1 628279 D 592205 CDS YP_003057408.1 254779303 8207842 628980..630692 1 NC_012973.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 630692 dnaX 8207842 dnaX Helicobacter pylori B38 DNA polymerase III subunits gamma and tau YP_003057408.1 628980 D 592205 CDS YP_003057409.1 254779304 8208471 630689..631090 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATPase 631090 8208471 HELPY_0650 Helicobacter pylori B38 ATPase YP_003057409.1 630689 D 592205 CDS YP_003057410.1 254779305 8207843 631103..631825 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter ATP-binding protein 631825 8207843 HELPY_0651 Helicobacter pylori B38 ABC transporter ATP-binding protein YP_003057410.1 631103 D 592205 CDS YP_003057411.1 254779306 8207844 631828..633072 1 NC_012973.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 633072 rpoN 8207844 rpoN Helicobacter pylori B38 RNA polymerase factor sigma-54 YP_003057411.1 631828 D 592205 CDS YP_003057412.1 254779307 8207846 complement(633760..634980) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 634980 8207846 HELPY_0655 Helicobacter pylori B38 hypothetical protein YP_003057412.1 633760 R 592205 CDS YP_003057413.1 254779308 8207847 complement(635170..637134) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185, 7534278; Product type m : membrane component; outer membrane protein HomA 637134 homA 8207847 homA Helicobacter pylori B38 outer membrane protein HomA YP_003057413.1 635170 R 592205 CDS YP_003057414.1 254779309 8208646 complement(637359..638261) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 638261 8208646 HELPY_0657 Helicobacter pylori B38 hypothetical protein YP_003057414.1 637359 R 592205 CDS YP_003057415.1 254779310 8207848 complement(638464..638808) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 638808 8207848 HELPY_0658 Helicobacter pylori B38 hypothetical protein YP_003057415.1 638464 R 592205 CDS YP_003057416.1 254779311 8207849 complement(638829..639755) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12153713, 10876091, 10572301, 9721276; Product type e : enzyme; S-adenosyl-methyltransferase MraW 639755 mraW 8207849 mraW Helicobacter pylori B38 S-adenosyl-methyltransferase MraW YP_003057416.1 638829 R 592205 CDS YP_003057417.1 254779312 8207850 complement(639933..640754) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7559328, 16102915, 15939494, 14742532, 12454143, 16322107, 16173498; Product type m : membrane component; outer membrane protein HopE 640754 hopE 8207850 hopE Helicobacter pylori B38 outer membrane protein HopE YP_003057417.1 639933 R 592205 CDS YP_003057418.1 254779313 8208652 640919..643744 1 NC_012973.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 643744 uvrA 8208652 uvrA Helicobacter pylori B38 excinuclease ABC subunit A YP_003057418.1 640919 D 592205 CDS YP_003057419.1 254779314 8209083 643775..643891 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 643891 8209083 HELPY_0662 Helicobacter pylori B38 hypothetical protein YP_003057419.1 643775 D 592205 CDS YP_003057420.1 254779315 8207853 complement(644987..646132) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; transcriptional activator 646132 flgR 8207853 flgR Helicobacter pylori B38 transcriptional activator YP_003057420.1 644987 R 592205 CDS YP_003057421.1 254779316 8208528 complement(646129..646602) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 646602 8208528 HELPY_0667 Helicobacter pylori B38 hypothetical protein YP_003057421.1 646129 R 592205 CDS YP_003057422.1 254779317 8207854 complement(646602..649085) 1 NC_012973.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 649085 gyrA 8207854 gyrA Helicobacter pylori B38 DNA gyrase subunit A YP_003057422.1 646602 R 592205 CDS YP_003057423.1 254779318 8208612 complement(649101..649487) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8071224, 12923107, 3015952, 3015952; Product type e : enzyme; Diacylglycerol kinase 649487 dgkA 8208612 dgkA Helicobacter pylori B38 Diacylglycerol kinase YP_003057423.1 649101 R 592205 CDS YP_003057424.1 254779319 8208461 complement(649480..650508) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 650508 8208461 HELPY_0670 Helicobacter pylori B38 hypothetical protein YP_003057424.1 649480 R 592205 CDS YP_003057425.1 254779320 8207855 complement(650519..650710) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 650710 8207855 HELPY_0671 Helicobacter pylori B38 hypothetical protein YP_003057425.1 650519 R 592205 CDS YP_003057426.1 254779321 8207856 complement(650897..651397) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 651397 8207856 HELPY_0673 Helicobacter pylori B38 hypothetical protein YP_003057426.1 650897 R 592205 CDS YP_003057427.1 254779322 8207857 complement(651414..653711) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10222578, 1732229; Product type pe : enzyme; N-methylhydantoinase 653711 8207857 HELPY_0674 Helicobacter pylori B38 N-methylhydantoinase YP_003057427.1 651414 R 592205 CDS YP_003057428.1 254779323 8207861 complement(656323..657333) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 657333 8207861 HELPY_0678 Helicobacter pylori B38 hypothetical protein YP_003057428.1 656323 R 592205 CDS YP_003057429.1 254779324 8207862 complement(657462..658832) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11267787, 2883171, 3025185; Product type t : transporter; Short-chain fatty acid transport protein, scFAT family; membrane protein 658832 atoE 8207862 atoE Helicobacter pylori B38 Short-chain fatty acid transport protein, scFAT family; membrane protein YP_003057429.1 657462 R 592205 CDS YP_003057430.1 254779325 8208392 complement(658846..659469) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9325289, 10091606, 10477312, 10477311, 10809701, 1624453, 9083111; Product type c : carrier; succinyl-CoA-transferase subunit B 659469 scoB 8208392 scoB Helicobacter pylori B38 succinyl-CoA-transferase subunit B YP_003057430.1 658846 R 592205 CDS YP_003057431.1 254779326 8209000 complement(659466..660164) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9325289, 10091606, 10477312, 10477311, 10809701, 1624453, 9083111; Product type c : carrier; succinyl-CoA-transferase subunit A 660164 scoA 8209000 scoA Helicobacter pylori B38 succinyl-CoA-transferase subunit A YP_003057431.1 659466 R 592205 CDS YP_003057432.1 254779327 8208999 complement(660175..661350) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; acetyl coenzyme A acetyltransferase 661350 8208999 HELPY_0683 Helicobacter pylori B38 acetyl coenzyme A acetyltransferase YP_003057432.1 660175 R 592205 CDS YP_003057433.1 254779328 8207863 complement(661634..662446) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 662446 8207863 HELPY_0684 Helicobacter pylori B38 hypothetical protein YP_003057433.1 661634 R 592205 CDS YP_003057434.1 254779329 8207864 662590..664518 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16041003, 15270747, 16718600, 10931324, 8407793, 16430693, 12781516; Product type t : transporter; Ferrous iron transport protein B; membrane protein 664518 feoB 8207864 feoB Helicobacter pylori B38 Ferrous iron transport protein B; membrane protein YP_003057434.1 662590 D 592205 CDS YP_003057435.1 254779330 8208505 664769..667072 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2836368, 10633096, 10713425, 12165031, 16718597, 16333751, 16193283; Product type pt : transporter; Iron(III) dicitrate transport protein FecA 667072 fecA1 8208505 fecA1 Helicobacter pylori B38 Iron(III) dicitrate transport protein FecA YP_003057435.1 664769 D 592205 CDS YP_003057436.1 254779331 8208501 complement(667109..667855) 1 NC_012973.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 667855 fliP 8208501 fliP Helicobacter pylori B38 flagellar biosynthesis protein FliP YP_003057436.1 667109 R 592205 CDS YP_003057437.1 254779332 8208542 667944..669245 1 NC_012973.1 [UDP-N-acetylglucosamine pyrophosphorylase N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase]; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 669245 glmU 8208542 glmU Helicobacter pylori B38 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_003057437.1 667944 D 592205 CDS YP_003057438.1 254779333 8208587 669446..669796 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 669796 8208587 HELPY_0689 Helicobacter pylori B38 hypothetical protein YP_003057438.1 669446 D 592205 CDS YP_003057439.1 254779334 8207865 669821..670303 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 670303 8207865 HELPY_0690 Helicobacter pylori B38 hypothetical protein YP_003057439.1 669821 D 592205 CDS YP_003057440.1 254779335 8207866 670471..672837 1 NC_012973.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 672837 nrdA 8207866 nrdA Helicobacter pylori B38 ribonucleotide-diphosphate reductase subunit alpha YP_003057440.1 670471 D 592205 CDS YP_003057441.1 254779336 8208804 672899..673846 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 673846 8208804 HELPY_0692 Helicobacter pylori B38 oxidoreductase YP_003057441.1 672899 D 592205 CDS YP_003057442.1 254779337 8207867 673959..674726 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type m : membrane component; hypothetical protein 674726 8207867 HELPY_0693 Helicobacter pylori B38 hypothetical protein YP_003057442.1 673959 D 592205 CDS YP_003057443.1 254779338 8207868 674730..675236 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12517410; Product type e : enzyme; methylated-DNA--protein-cysteine methyltransferase (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase) 675236 ogt 8207868 ogt Helicobacter pylori B38 methylated-DNA--protein-cysteine methyltransferase (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase) YP_003057443.1 674730 D 592205 CDS YP_003057444.1 254779339 8208826 complement(675301..676371) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; integrase/recombinase 676371 8208826 HELPY_0695 Helicobacter pylori B38 integrase/recombinase YP_003057444.1 675301 R 592205 CDS YP_003057445.1 254779340 8207869 complement(676385..676978) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 676978 8207869 HELPY_0696 Helicobacter pylori B38 hypothetical protein YP_003057445.1 676385 R 592205 CDS YP_003057446.1 254779341 8207870 complement(677475..678647) 1 NC_012973.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 678647 aspB 8207870 aspB Helicobacter pylori B38 aspartate aminotransferase YP_003057446.1 677475 R 592205 CDS YP_003057447.1 254779342 8208389 complement(678810..679622) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HorF 679622 horF 8208389 horF Helicobacter pylori B38 outer membrane protein HorF YP_003057447.1 678810 R 592205 CDS YP_003057448.1 254779343 8207871 complement(683721..684950) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 684950 8207871 HELPY_0700 Helicobacter pylori B38 transposase, OrfB, ISHp609 YP_003057448.1 683721 R 592205 CDS YP_003057449.1 254779344 8207872 complement(684937..685569) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 685569 8207872 HELPY_0701 Helicobacter pylori B38 Serine recombinase-transposase, OrfA, ISHp609 YP_003057449.1 684937 R 592205 CDS YP_003057450.1 254779345 8207873 complement(685566..685751) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 685751 8207873 HELPY_0702 Helicobacter pylori B38 hypothetical protein YP_003057450.1 685566 R 592205 CDS YP_003057451.1 254779346 8207874 complement(685753..686010) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 686010 8207874 HELPY_0703 Helicobacter pylori B38 hypothetical protein YP_003057451.1 685753 R 592205 CDS YP_003057452.1 254779347 8207876 complement(687102..688403) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; anaerobic glycerol-3-phosphate dehydrogenase (G-3-P dehydrogenase) 688403 8207876 HELPY_0705 Helicobacter pylori B38 anaerobic glycerol-3-phosphate dehydrogenase (G-3-P dehydrogenase) YP_003057452.1 687102 R 592205 CDS YP_003057453.1 254779348 8207877 complement(688400..689773) 1 NC_012973.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 689773 hemN 8207877 hemN Helicobacter pylori B38 coproporphyrinogen III oxidase YP_003057453.1 688400 R 592205 CDS YP_003057454.1 254779349 8208632 complement(689773..690288) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 690288 8208632 HELPY_0707 Helicobacter pylori B38 hypothetical protein YP_003057454.1 689773 R 592205 CDS YP_003057455.1 254779350 8207878 complement(690325..691422) 1 NC_012973.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 691422 aroC 8207878 aroC Helicobacter pylori B38 chorismate synthase YP_003057455.1 690325 R 592205 CDS YP_003057456.1 254779351 8208382 complement(691419..692117) 1 NC_012973.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 692117 rnc 8208382 rnc Helicobacter pylori B38 ribonuclease III YP_003057456.1 691419 R 592205 CDS YP_003057457.1 254779352 8208928 complement(692129..692560) 1 NC_012973.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 692560 rnhA 8208928 rnhA Helicobacter pylori B38 ribonuclease H YP_003057457.1 692129 R 592205 CDS YP_003057458.1 254779353 8208929 complement(692547..693566) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 693566 8208929 HELPY_0711 Helicobacter pylori B38 hypothetical protein YP_003057458.1 692547 R 592205 CDS YP_003057459.1 254779354 8207879 complement(693577..694839) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 694839 8207879 HELPY_0712 Helicobacter pylori B38 hypothetical protein YP_003057459.1 693577 R 592205 CDS YP_003057460.1 254779355 8207880 complement(694839..696263) 1 NC_012973.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 696263 gatB 8207880 gatB Helicobacter pylori B38 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_003057460.1 694839 R 592205 CDS YP_003057461.1 254779356 8208578 complement(696263..697525) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 697525 8208578 HELPY_0714 Helicobacter pylori B38 hypothetical protein YP_003057461.1 696263 R 592205 CDS YP_003057462.1 254779357 8207881 complement(697570..698631) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 698631 8207881 HELPY_0715 Helicobacter pylori B38 hypothetical protein YP_003057462.1 697570 R 592205 CDS YP_003057463.1 254779358 8207882 complement(698633..701413) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; surface antigen protein 701413 8207882 HELPY_0716 Helicobacter pylori B38 surface antigen protein YP_003057463.1 698633 R 592205 CDS YP_003057464.1 254779359 8207883 complement(701451..702533) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 702533 8207883 HELPY_0717 Helicobacter pylori B38 hypothetical protein YP_003057464.1 701451 R 592205 CDS YP_003057465.1 254779360 8207884 702831..703334 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12065536, 9782498; Product type c : carrier; Nonheme iron-containing ferritin (iron storage protein) 703334 pfr 8207884 pfr Helicobacter pylori B38 Nonheme iron-containing ferritin (iron storage protein) YP_003057465.1 702831 D 592205 CDS YP_003057466.1 254779361 8208851 703350..703973 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16269752, 2997734; Product type e : enzyme; phosphoserine phosphatase 703973 serB 8208851 serB Helicobacter pylori B38 phosphoserine phosphatase YP_003057466.1 703350 D 592205 CDS YP_003057467.1 254779362 8209011 704013..705422 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16477004, 15058985, 10496917; Product type e : enzyme; Alpha1,3-fucosyltransferase 705422 futB 8209011 futB Helicobacter pylori B38 Alpha1,3-fucosyltransferase YP_003057467.1 704013 D 592205 CDS YP_003057468.1 254779363 8208572 complement(705431..706060) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transferase 706060 8208572 HELPY_0721 Helicobacter pylori B38 transferase YP_003057468.1 705431 R 592205 CDS YP_003057469.1 254779364 8207885 complement(706066..707472) 1 NC_012973.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 707472 aspA 8207885 aspA Helicobacter pylori B38 aspartate ammonia-lyase YP_003057469.1 706066 R 592205 CDS YP_003057470.1 254779365 8208388 complement(707530..708798) 1 NC_012973.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 708798 murA 8208388 murA Helicobacter pylori B38 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_003057470.1 707530 R 592205 CDS YP_003057471.1 254779366 8208783 complement(708801..709208) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 709208 8208783 HELPY_0724 Helicobacter pylori B38 hypothetical protein YP_003057471.1 708801 R 592205 CDS YP_003057472.1 254779367 8207886 complement(709220..710041) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16132460, 15240254, 15213167; Product type e : enzyme; UTP-glucose-1-phosphate uridylyltransferase 710041 galU 8207886 galU Helicobacter pylori B38 UTP-glucose-1-phosphate uridylyltransferase YP_003057472.1 709220 R 592205 CDS YP_003057473.1 254779368 8208575 complement(710038..711720) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; soluble lytic murein transglycosylase 711720 8208575 HELPY_0726 Helicobacter pylori B38 soluble lytic murein transglycosylase YP_003057473.1 710038 R 592205 CDS YP_003057474.1 254779369 8207887 complement(711729..712022) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 712022 8207887 HELPY_0727 Helicobacter pylori B38 hypothetical protein YP_003057474.1 711729 R 592205 CDS YP_003057475.1 254779370 8207888 complement(712019..713338) 1 NC_012973.1 charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase 713338 gltX2 8207888 gltX2 Helicobacter pylori B38 glutamylglutaminyl-tRNA synthetase YP_003057475.1 712019 R 592205 CDS YP_003057476.1 254779371 8208592 complement(713503..714156) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16426819, 15856372, 15496391, 1549639, 12648728; Product type e : enzyme; NAD(P)H-flavin oxidoreductase 714156 frxA 8208592 frxA Helicobacter pylori B38 NAD(P)H-flavin oxidoreductase YP_003057476.1 713503 R 592205 CDS YP_003057477.1 254779372 8208561 complement(714158..715015) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12729017; Product type pe : enzyme; 3-hydroxyacid dehydrogenase 715015 8208561 HELPY_0730 Helicobacter pylori B38 3-hydroxyacid dehydrogenase YP_003057477.1 714158 R 592205 CDS YP_003057478.1 254779373 8207889 complement(715183..716391) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10684583; Product type pe : enzyme; polynucleotide adenylyltransferase; poly(A) polymerase 716391 8207889 HELPY_0731 Helicobacter pylori B38 polynucleotide adenylyltransferase; poly(A) polymerase YP_003057478.1 715183 R 592205 CDS YP_003057479.1 254779374 8207890 716454..717140 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 717140 8207890 HELPY_0732 Helicobacter pylori B38 hypothetical protein YP_003057479.1 716454 D 592205 CDS YP_003057480.1 254779375 8207891 complement(717209..718183) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 15457576, 15131212, 10852959; Product type m : membrane component; outer membrane protein HopH 718183 hopH 8207891 hopH Helicobacter pylori B38 outer membrane protein HopH YP_003057480.1 717209 R 592205 CDS YP_003057481.1 254779376 8208655 718314..718766 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 718766 8208655 HELPY_0734 Helicobacter pylori B38 hypothetical protein YP_003057481.1 718314 D 592205 CDS YP_003057482.1 254779377 8207892 718903..719316 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 719316 8207892 HELPY_0735 Helicobacter pylori B38 hypothetical protein YP_003057482.1 718903 D 592205 CDS YP_003057483.1 254779378 8207893 complement(719321..720859) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 720859 8207893 HELPY_0736 Helicobacter pylori B38 hypothetical protein YP_003057483.1 719321 R 592205 CDS YP_003057484.1 254779379 8207894 complement(720861..721397) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233; Product type e : enzyme; Endoprotease involved hydrogenase maturation 721397 hydD 8207894 hydD Helicobacter pylori B38 Endoprotease involved hydrogenase maturation YP_003057484.1 720861 R 592205 CDS YP_003057485.1 254779380 8208698 complement(721394..722068) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 8764511; Product type e : enzyme; Quinone-reactive Ni/Fe hydrogenase cytochrome b subunit 722068 hydC 8208698 hydC Helicobacter pylori B38 Quinone-reactive Ni/Fe hydrogenase cytochrome b subunit YP_003057485.1 721394 R 592205 CDS YP_003057486.1 254779381 8208697 complement(722081..723817) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 11123699, 8764511; Product type e : enzyme; Quinone-reactive Ni/Fe-hydrogenase large chain 723817 hydB 8208697 hydB Helicobacter pylori B38 Quinone-reactive Ni/Fe-hydrogenase large chain YP_003057486.1 722081 R 592205 CDS YP_003057487.1 254779382 8208696 complement(723827..724981) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11123699, 8764511; Product type e : enzyme; Quinone-reactive Ni/Fe hydrogenase small subunit 724981 hydA 8208696 hydA Helicobacter pylori B38 Quinone-reactive Ni/Fe hydrogenase small subunit YP_003057487.1 723827 R 592205 CDS YP_003057488.1 254779383 8208695 725144..725728 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14977943, 16511004, 8611590; Product type e : enzyme; NAD(P)H oxidoreductase (NADPH quinone reductase) 725728 mdaB 8208695 mdaB Helicobacter pylori B38 NAD(P)H oxidoreductase (NADPH quinone reductase) YP_003057488.1 725144 D 592205 CDS YP_003057489.1 254779384 8207896 complement(728059..729117) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 729117 8207896 HELPY_0744 Helicobacter pylori B38 hypothetical protein YP_003057489.1 728059 R 592205 CDS YP_003057490.1 254779385 8207897 complement(729129..730334) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10508663, 10850974, 9012664; Product type e : enzyme; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 730334 dapD 8207897 dapD Helicobacter pylori B38 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_003057490.1 729129 R 592205 CDS YP_003057491.1 254779386 8208450 complement(730337..731416) 1 NC_012973.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 731416 ispG 8208450 ispG Helicobacter pylori B38 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_003057491.1 730337 R 592205 CDS YP_003057492.1 254779387 8208719 731536..732663 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12670965; Product type e : enzyme; hypothetical protein 732663 aspB 8208719 aspB Helicobacter pylori B38 hypothetical protein YP_003057492.1 731536 D 592205 CDS YP_003057493.1 254779388 8208390 732656..734005 1 NC_012973.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 734005 murC 8208390 murC Helicobacter pylori B38 UDP-N-acetylmuramate--L-alanine ligase YP_003057493.1 732656 D 592205 CDS YP_003057494.1 254779389 8208785 734005..734382 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 734382 8208785 HELPY_0749 Helicobacter pylori B38 hypothetical protein YP_003057494.1 734005 D 592205 CDS YP_003057495.1 254779390 8207898 734389..736638 1 NC_012973.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 736638 mutS 8207898 mutS Helicobacter pylori B38 recombination and DNA strand exchange inhibitor protein YP_003057495.1 734389 D 592205 CDS YP_003057496.1 254779391 8208791 complement(736780..737301) 1 NC_012973.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 737301 ppa 8208791 ppa Helicobacter pylori B38 inorganic pyrophosphatase YP_003057496.1 736780 R 592205 CDS YP_003057497.1 254779392 8207900 complement(738673..739248) 1 NC_012973.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 739248 adk 8207900 adk Helicobacter pylori B38 adenylate kinase YP_003057497.1 738673 R 592205 CDS YP_003057498.1 254779393 8208370 complement(739265..740998) 1 NC_012973.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 740998 aspS 8208370 aspS Helicobacter pylori B38 aspartyl-tRNA synthetase YP_003057498.1 739265 R 592205 CDS YP_003057499.1 254779394 8208391 complement(741033..741974) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11535789, 8169224, 8169223; Product type pf : factor; Chemotaxis protein 741974 cheV2 8208391 cheV2 Helicobacter pylori B38 Chemotaxis protein YP_003057499.1 741033 R 592205 CDS YP_003057500.1 254779395 8208421 742052..744022 1 NC_012973.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 744022 ligA 8208421 ligA Helicobacter pylori B38 NAD-dependent DNA ligase LigA YP_003057500.1 742052 D 592205 CDS YP_003057501.1 254779396 8208731 744176..744508 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 744508 8208731 HELPY_0758 Helicobacter pylori B38 hypothetical protein YP_003057501.1 744176 D 592205 CDS YP_003057502.1 254779397 8207905 complement(746315..755878) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16610017, 16579839, 16579837, 16552038, 16497614, 16489309; Product type pm : membrane component; vacuolating cytotoxin VacA-like 755878 8207905 HELPY_0763 Helicobacter pylori B38 vacuolating cytotoxin VacA-like YP_003057502.1 746315 R 592205 CDS YP_003057503.1 254779398 8207906 complement(756045..756614) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 756614 8207906 HELPY_0764 Helicobacter pylori B38 hypothetical protein YP_003057503.1 756045 R 592205 CDS YP_003057504.1 254779399 8207907 complement(756611..759700) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10639345, 7651136, 8987357, 8830678; Product type m : membrane component; Cytoplasmic pump proteins of the hefABC efflux system 759700 hefC 8207907 hefC Helicobacter pylori B38 Cytoplasmic pump proteins of the hefABC efflux system YP_003057504.1 756611 R 592205 CDS YP_003057505.1 254779400 8208623 complement(759710..760414) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10639345, 7651136, 8987357, 8830678; Product type m : membrane component; Membrane fusion protein of the hefABC efflux system 760414 hefB 8208623 hefB Helicobacter pylori B38 Membrane fusion protein of the hefABC efflux system YP_003057505.1 759710 R 592205 CDS YP_003057506.1 254779401 8208622 complement(760425..761858) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10639345, 7651136, 8987357, 8830678; Product type m : membrane component; outer-membrane protein of the hefABC efflux system 761858 hefA 8208622 hefA Helicobacter pylori B38 outer-membrane protein of the hefABC efflux system YP_003057506.1 760425 R 592205 CDS YP_003057507.1 254779402 8208621 complement(761868..762887) 1 NC_012973.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 762887 hemE 8208621 hemE Helicobacter pylori B38 uroporphyrinogen decarboxylase YP_003057507.1 761868 R 592205 CDS YP_003057508.1 254779403 8208628 complement(762956..763573) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 763573 8208628 HELPY_0769 Helicobacter pylori B38 hypothetical protein YP_003057508.1 762956 R 592205 CDS YP_003057509.1 254779404 8207908 complement(763570..764226) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10777493, 16468998; Product type e : enzyme; 3-methyladenine DNA glycosylase 764226 magIII 8207908 magIII Helicobacter pylori B38 3-methyladenine DNA glycosylase YP_003057509.1 763570 R 592205 CDS YP_003057510.1 254779405 8208748 complement(764354..765886) 1 NC_012973.1 FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A 765886 flaA 8208748 flaA Helicobacter pylori B38 flagellin A YP_003057510.1 764354 R 592205 CDS YP_003057511.1 254779406 8208511 766039..767820 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12504680; Product type t : transporter; ABC transporter permease and ATP-binding protein; membrane protein 767820 8208511 HELPY_0772 Helicobacter pylori B38 ABC transporter permease and ATP-binding protein; membrane protein YP_003057511.1 766039 D 592205 CDS YP_003057512.1 254779407 8207909 767892..769193 1 NC_012973.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10456921, 8809743; Product type m : membrane component; methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) 769193 8207909 HELPY_0773 Helicobacter pylori B38 methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) YP_003057512.1 767892 D 592205 CDS YP_003057513.1 254779408 8207910 769216..770337 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11255013, 8763940, 3058702; Product type e : enzyme; 8-amino-7-oxononanoate synthase 770337 bioF 8207910 bioF Helicobacter pylori B38 8-amino-7-oxononanoate synthase YP_003057513.1 769216 D 592205 CDS YP_003057514.1 254779409 8208408 770338..772317 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16684266, 12461003, 12069978, 11181392, 11083642, 10797079; Product type e : enzyme; Penicillin-binding protein 1 (peptidoglycan glycosyltransferase) 772317 pbpA 8208408 pbpA Helicobacter pylori B38 Penicillin-binding protein 1 (peptidoglycan glycosyltransferase) YP_003057514.1 770338 D 592205 CDS YP_003057515.1 254779410 8208841 complement(772320..772898) 1 NC_012973.1 Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein 772898 8208841 HELPY_0776 Helicobacter pylori B38 tumor necrosis factor alpha-inducing protein YP_003057515.1 772320 R 592205 CDS YP_003057516.1 254779411 8207911 complement(773123..773245) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 773245 8207911 HELPY_0778 Helicobacter pylori B38 hypothetical protein YP_003057516.1 773123 R 592205 CDS YP_003057517.1 254779412 8207912 complement(773377..774849) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; disulfide oxidoreductase B (DsbB-like protein); membrane protein 774849 8207912 HELPY_0779 Helicobacter pylori B38 disulfide oxidoreductase B (DsbB-like protein); membrane protein YP_003057517.1 773377 R 592205 CDS YP_003057518.1 254779413 8207913 complement(774859..775023) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 775023 8207913 HELPY_0780 Helicobacter pylori B38 hypothetical protein YP_003057518.1 774859 R 592205 CDS YP_003057519.1 254779414 8207914 complement(775124..777058) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; type III restriction enzyme M protein 777058 8207914 HELPY_0781 Helicobacter pylori B38 type III restriction enzyme M protein YP_003057519.1 775124 R 592205 CDS YP_003057520.1 254779415 8207915 complement(777055..780000) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type III restriction enzyme R protein 780000 8207915 HELPY_0782 Helicobacter pylori B38 type III restriction enzyme R protein YP_003057520.1 777055 R 592205 CDS YP_003057521.1 254779416 8207916 complement(780155..780715) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type e : enzyme; 2-oxoglutarate-acceptor oxidoreductase subunit OorC 780715 oorC 8207916 oorC Helicobacter pylori B38 2-oxoglutarate-acceptor oxidoreductase subunit OorC YP_003057521.1 780155 R 592205 CDS YP_003057522.1 254779417 8208831 complement(780715..781536) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type e : enzyme; 2-oxoglutarate-acceptor oxidoreductase subunit OorB 781536 oorB 8208831 oorB Helicobacter pylori B38 2-oxoglutarate-acceptor oxidoreductase subunit OorB YP_003057522.1 780715 R 592205 CDS YP_003057523.1 254779418 8208830 complement(781538..782665) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type e : enzyme; 2-oxoglutarate-acceptor oxidoreductase subunit OorA 782665 oorA 8208830 oorA Helicobacter pylori B38 2-oxoglutarate-acceptor oxidoreductase subunit OorA YP_003057523.1 781538 R 592205 CDS YP_003057524.1 254779419 8208829 complement(782665..783006) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type c : carrier; 2-oxoglutarate-acceptor oxidoreductase subunit OorD 783006 oorD 8208829 oorD Helicobacter pylori B38 2-oxoglutarate-acceptor oxidoreductase subunit OorD YP_003057524.1 782665 R 592205 CDS YP_003057525.1 254779420 8208832 complement(783190..784179) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14745019, 11011151; Product type e : enzyme; Aminodeoxychorismate lyase 784179 pabC 8208832 pabC Helicobacter pylori B38 Aminodeoxychorismate lyase YP_003057525.1 783190 R 592205 CDS YP_003057526.1 254779421 8208834 784097..787030 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 787030 8208834 HELPY_0788 Helicobacter pylori B38 hypothetical protein YP_003057526.1 784097 D 592205 CDS YP_003057527.1 254779422 8207917 787032..787262 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 787262 8207917 HELPY_0789 Helicobacter pylori B38 hypothetical protein YP_003057527.1 787032 D 592205 CDS YP_003057528.1 254779423 8207918 787265..787915 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12601164; Product type e : enzyme; endonuclease III 787915 nth 8207918 nth Helicobacter pylori B38 endonuclease III YP_003057528.1 787265 D 592205 CDS YP_003057529.1 254779424 8208808 787997..788368 1 NC_012973.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 788368 fliN 8208808 fliN Helicobacter pylori B38 flagellar motor switch protein YP_003057529.1 787997 D 592205 CDS YP_003057530.1 254779425 8208541 788365..789246 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 789246 8208541 HELPY_0792 Helicobacter pylori B38 hypothetical protein YP_003057530.1 788365 D 592205 CDS YP_003057531.1 254779426 8207919 789230..790204 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; siderophore-mediated iron transport protein 790204 8207919 HELPY_0793 Helicobacter pylori B38 siderophore-mediated iron transport protein YP_003057531.1 789230 D 592205 CDS YP_003057532.1 254779427 8207920 790208..791227 1 NC_012973.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 791227 pyrC2 8207920 pyrC2 Helicobacter pylori B38 dihydroorotase YP_003057532.1 790208 D 592205 CDS YP_003057533.1 254779428 8208893 791245..792321 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 792321 8208893 HELPY_0795 Helicobacter pylori B38 hypothetical protein YP_003057533.1 791245 D 592205 CDS YP_003057534.1 254779429 8207921 792328..792882 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 792882 8207921 HELPY_0797 Helicobacter pylori B38 hypothetical protein YP_003057534.1 792328 D 592205 CDS YP_003057535.1 254779430 8207922 792888..794939 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 794939 8207922 HELPY_0798 Helicobacter pylori B38 hypothetical protein YP_003057535.1 792888 D 592205 CDS YP_003057536.1 254779431 8207923 795165..796037 1 NC_012973.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 796037 folD 8207923 folD Helicobacter pylori B38 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_003057536.1 795165 D 592205 CDS YP_003057537.1 254779432 8208550 796037..796909 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16126156, 15546672, 12423785, 9194173; Product type e : enzyme; Signal peptidase I (SPase I) (Leader peptidase I) 796909 lepB 8208550 lepB Helicobacter pylori B38 Signal peptidase I (SPase I) (Leader peptidase I) YP_003057537.1 796037 D 592205 CDS YP_003057538.1 254779433 8208728 796918..797616 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 797616 8208728 HELPY_0801 Helicobacter pylori B38 hypothetical protein YP_003057538.1 796918 D 592205 CDS YP_003057539.1 254779434 8207924 797649..798098 1 NC_012973.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 798098 rpi 8207924 rpi Helicobacter pylori B38 ribose-5-phosphate isomerase B YP_003057539.1 797649 D 592205 CDS YP_003057540.1 254779435 8208937 798165..798497 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 798497 8208937 HELPY_0803 Helicobacter pylori B38 hypothetical protein YP_003057540.1 798165 D 592205 CDS YP_003057541.1 254779436 8207925 798555..799094 1 NC_012973.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 799094 apt 8207925 apt Helicobacter pylori B38 adenine phosphoribosyltransferase YP_003057541.1 798555 D 592205 CDS YP_003057542.1 254779437 8208378 799109..799687 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 799687 8208378 HELPY_0805 Helicobacter pylori B38 hypothetical protein YP_003057542.1 799109 D 592205 CDS YP_003057543.1 254779438 8207926 799735..801225 1 NC_012973.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 801225 pepA 8207926 pepA Helicobacter pylori B38 leucyl aminopeptidase YP_003057543.1 799735 D 592205 CDS YP_003057544.1 254779439 8208845 801227..802327 1 NC_012973.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 802327 gtp1 8208845 gtp1 Helicobacter pylori B38 GTP-dependent nucleic acid-binding protein EngD YP_003057544.1 801227 D 592205 CDS YP_003057545.1 254779440 8208608 802462..803229 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 803229 8208608 HELPY_0808 Helicobacter pylori B38 hypothetical protein YP_003057545.1 802462 D 592205 CDS YP_003057546.1 254779441 8207927 complement(803297..804343) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type m : membrane component; hypothetical protein 804343 8207927 HELPY_0810 Helicobacter pylori B38 hypothetical protein YP_003057546.1 803297 R 592205 CDS YP_003057547.1 254779442 8207928 804458..805276 1 NC_012973.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 805276 dapF 8207928 dapF Helicobacter pylori B38 diaminopimelate epimerase YP_003057547.1 804458 D 592205 CDS YP_003057548.1 254779443 8208452 805389..806036 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type m : membrane component; hypothetical protein 806036 8208452 HELPY_0812 Helicobacter pylori B38 hypothetical protein YP_003057548.1 805389 D 592205 CDS YP_003057549.1 254779444 8207929 complement(806060..806305) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 806305 8207929 HELPY_0813 Helicobacter pylori B38 hypothetical protein YP_003057549.1 806060 R 592205 CDS YP_003057550.1 254779445 8207930 806477..807727 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 807727 8207930 HELPY_0814 Helicobacter pylori B38 hypothetical protein YP_003057550.1 806477 D 592205 CDS YP_003057551.1 254779446 8207931 807828..808040 1 NC_012973.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 808040 rpsU 8207931 rpsU Helicobacter pylori B38 30S ribosomal protein S21 YP_003057551.1 807828 D 592205 CDS YP_003057552.1 254779447 8208995 808079..808822 1 NC_012973.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 808822 fabG 8208995 fabG Helicobacter pylori B38 3-ketoacyl-ACP reductase YP_003057552.1 808079 D 592205 CDS YP_003057553.1 254779448 8208495 809053..809289 1 NC_012973.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 809289 acpP 8208495 acpP Helicobacter pylori B38 acyl carrier protein YP_003057553.1 809053 D 592205 CDS YP_003057554.1 254779449 8208366 809393..810631 1 NC_012973.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 810631 fabF 8208366 fabF Helicobacter pylori B38 3-oxoacyl-(acyl carrier protein) synthase II YP_003057554.1 809393 D 592205 CDS YP_003057555.1 254779450 8208494 810654..811592 1 NC_012973.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 811592 accA 8208494 accA Helicobacter pylori B38 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_003057555.1 810654 D 592205 CDS YP_003057556.1 254779451 8208361 812061..812498 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 812498 8208361 HELPY_0820 Helicobacter pylori B38 hypothetical protein YP_003057556.1 812061 D 592205 CDS YP_003057557.1 254779452 8207932 complement(812568..813389) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 813389 8207932 HELPY_0821 Helicobacter pylori B38 hypothetical protein YP_003057557.1 812568 R 592205 CDS YP_003057558.1 254779453 8207933 complement(813386..814351) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 814351 8207933 HELPY_0822 Helicobacter pylori B38 hypothetical protein YP_003057558.1 813386 R 592205 CDS YP_003057559.1 254779454 8207934 complement(814364..815047) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2401410; Product type e : enzyme; 23S rRNA methyltransferase 815047 nshR 8207934 nshR Helicobacter pylori B38 23S rRNA methyltransferase YP_003057559.1 814364 R 592205 CDS YP_003057560.1 254779455 8208806 complement(815060..815923) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methylase 815923 8208806 HELPY_0824 Helicobacter pylori B38 methylase YP_003057560.1 815060 R 592205 CDS YP_003057561.1 254779456 8207935 complement(815948..816151) 1 NC_012973.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 816151 rpmE 8207935 rpmE Helicobacter pylori B38 50S ribosomal protein L31 YP_003057561.1 815948 R 592205 CDS YP_003057562.1 254779457 8208964 816414..817730 1 NC_012973.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 817730 rho 8208964 rho Helicobacter pylori B38 transcription termination factor Rho YP_003057562.1 816414 D 592205 CDS YP_003057563.1 254779458 8208916 817768..818535 1 NC_012973.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 818535 murI 8208916 murI Helicobacter pylori B38 glutamate racemase YP_003057563.1 817768 D 592205 CDS YP_003057564.1 254779459 8208790 818547..819401 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 819401 8208790 HELPY_0828 Helicobacter pylori B38 hypothetical protein YP_003057564.1 818547 D 592205 CDS YP_003057565.1 254779460 8207936 complement(819485..820477) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 820477 8207936 HELPY_0829 Helicobacter pylori B38 hypothetical protein YP_003057565.1 819485 R 592205 CDS YP_003057566.1 254779461 8207937 complement(820474..821379) 1 NC_012973.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 821379 era 8207937 era Helicobacter pylori B38 GTP-binding protein Era YP_003057566.1 820474 R 592205 CDS YP_003057567.1 254779462 8208486 complement(821379..822710) 1 NC_012973.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 822710 hslU 8208486 hslU Helicobacter pylori B38 ATP-dependent protease ATP-binding subunit HslU YP_003057567.1 821379 R 592205 CDS YP_003057568.1 254779463 8208691 complement(822710..823252) 1 NC_012973.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 823252 hsp20 8208691 hsp20 Helicobacter pylori B38 ATP-dependent protease peptidase subunit YP_003057568.1 822710 R 592205 CDS YP_003057569.1 254779464 8208692 complement(823256..823705) 1 NC_012973.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 823705 rplI 8208692 rplI Helicobacter pylori B38 50S ribosomal protein L9 YP_003057569.1 823256 R 592205 CDS YP_003057570.1 254779465 8207938 complement(824052..825281) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 825281 8207938 HELPY_0835 Helicobacter pylori B38 transposase, OrfB, ISHp609 YP_003057570.1 824052 R 592205 CDS YP_003057571.1 254779466 8207939 complement(825268..825900) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 825900 8207939 HELPY_0836 Helicobacter pylori B38 Serine recombinase-transposase, OrfA, ISHp609 YP_003057571.1 825268 R 592205 CDS YP_003057572.1 254779467 8207940 complement(825897..826082) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 826082 8207940 HELPY_0837 Helicobacter pylori B38 hypothetical protein YP_003057572.1 825897 R 592205 CDS YP_003057573.1 254779468 8207941 complement(826084..826302) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 826302 8207941 HELPY_0838 Helicobacter pylori B38 hypothetical protein YP_003057573.1 826084 R 592205 CDS YP_003057574.1 254779469 8207943 828425..829870 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11390701, 9573059, 1612427, 2574599; Product type e : enzyme; glutamine synthetase 829870 glnA 8207943 glnA Helicobacter pylori B38 glutamine synthetase YP_003057574.1 828425 D 592205 CDS YP_003057575.1 254779470 8208588 complement(829926..830072) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 830072 8208588 HELPY_0841 Helicobacter pylori B38 hypothetical protein YP_003057575.1 829926 R 592205 CDS YP_003057576.1 254779471 8207944 complement(830097..830267) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10198012, 18227160; Product type lp : lipoprotein; urease-enhancing factor Lpp 830267 lpp 8207944 lpp Helicobacter pylori B38 urease-enhancing factor Lpp YP_003057576.1 830097 R 592205 CDS YP_003057577.1 254779472 8208736 complement(830698..831462) 1 NC_012973.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 831462 dapB 8208736 dapB Helicobacter pylori B38 dihydrodipicolinate reductase YP_003057577.1 830698 R 592205 CDS YP_003057578.1 254779473 8208449 complement(831485..832864) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11283302, 8606183; Product type e : enzyme; glycolate oxidase subunit 832864 glcD 8208449 glcD Helicobacter pylori B38 glycolate oxidase subunit YP_003057578.1 831485 R 592205 CDS YP_003057579.1 254779474 8208584 complement(832866..834215) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 834215 8208584 HELPY_0845 Helicobacter pylori B38 hypothetical protein YP_003057579.1 832866 R 592205 CDS YP_003057580.1 254779475 8207945 complement(834226..834864) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 834864 8207945 HELPY_0846 Helicobacter pylori B38 hypothetical protein YP_003057580.1 834226 R 592205 CDS YP_003057581.1 254779476 8207946 complement(834864..836084) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 836084 8207946 HELPY_0847 Helicobacter pylori B38 hypothetical protein YP_003057581.1 834864 R 592205 CDS YP_003057582.1 254779477 8207949 complement(837029..838021) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 838021 8207949 HELPY_0850 Helicobacter pylori B38 hypothetical protein YP_003057582.1 837029 R 592205 CDS YP_003057583.1 254779478 8207950 complement(838067..840388) 1 NC_012973.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 840388 gyrB 8207950 gyrB Helicobacter pylori B38 DNA gyrase subunit B YP_003057583.1 838067 R 592205 CDS YP_003057584.1 254779479 8208613 complement(840401..841525) 1 NC_012973.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 841525 dnaN 8208613 dnaN Helicobacter pylori B38 DNA polymerase III subunit beta YP_003057584.1 840401 R 592205 CDS YP_003057585.1 254779480 8207952 complement(842664..843992) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9779464, 8031825; Product type pt : transporter; sodium-and chloride-dependent transporter; membrane protein 843992 8207952 HELPY_0855 Helicobacter pylori B38 sodium-and chloride-dependent transporter; membrane protein YP_003057585.1 842664 R 592205 CDS YP_003057586.1 254779481 8207953 complement(844003..845331) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9779464, 8031825; Product type pt : transporter; sodium-and chloride-dependent transporter; membrane protein 845331 8207953 HELPY_0856 Helicobacter pylori B38 sodium-and chloride-dependent transporter; membrane protein YP_003057586.1 844003 R 592205 CDS YP_003057587.1 254779482 8207954 845561..845962 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioesterase 845962 8207954 HELPY_0857 Helicobacter pylori B38 thioesterase YP_003057587.1 845561 D 592205 CDS YP_003057588.1 254779483 8207955 845952..846212 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 846212 8207955 HELPY_0858 Helicobacter pylori B38 hypothetical protein YP_003057588.1 845952 D 592205 CDS YP_003057589.1 254779484 8207956 complement(846209..847477) 1 NC_012973.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 847477 murD 8207956 murD Helicobacter pylori B38 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_003057589.1 846209 R 592205 CDS YP_003057590.1 254779485 8208786 complement(847479..848540) 1 NC_012973.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 848540 mraY 8208786 mraY Helicobacter pylori B38 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_003057590.1 847479 R 592205 CDS YP_003057591.1 254779486 8208778 848666..849502 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16953581, 16428735, 15609408, 11855744, 9287032, 8487294, 7678592; Product type lp : lipoprotein; Neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin); signal peptide 849502 hpaA 8208778 hpaA Helicobacter pylori B38 Neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin); signal peptide YP_003057591.1 848666 D 592205 CDS YP_003057592.1 254779487 8208675 849602..849790 1 NC_012973.1 required for 70S ribosome assembly; 50S ribosomal protein L28 849790 rpmB 8208675 rpmB Helicobacter pylori B38 50S ribosomal protein L28 YP_003057592.1 849602 D 592205 CDS YP_003057593.1 254779488 8208938 849973..851109 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; potassium channel protein 851109 8208938 HELPY_0864 Helicobacter pylori B38 potassium channel protein YP_003057593.1 849973 D 592205 CDS YP_003057594.1 254779489 8207957 complement(851464..852318) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 852318 8207957 HELPY_0865 Helicobacter pylori B38 hypothetical protein YP_003057594.1 851464 R 592205 CDS YP_003057595.1 254779490 8207960 complement(855214..855765) 1 NC_012973.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 855765 ruvA 8207960 ruvA Helicobacter pylori B38 Holliday junction DNA helicase RuvA YP_003057595.1 855214 R 592205 CDS YP_003057596.1 254779491 8208996 complement(855791..857635) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 857635 8208996 HELPY_0869 Helicobacter pylori B38 hypothetical protein YP_003057596.1 855791 R 592205 CDS YP_003057597.1 254779492 8207961 857801..859186 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11930024, 11274131, 2680969; Product type pf : factor; virulence factor MviN protein; membrane protein 859186 8207961 HELPY_0870 Helicobacter pylori B38 virulence factor MviN protein; membrane protein YP_003057597.1 857801 D 592205 CDS YP_003057598.1 254779493 8207962 859187..860584 1 NC_012973.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 860584 cysS 8207962 cysS Helicobacter pylori B38 cysteinyl-tRNA synthetase YP_003057598.1 859187 D 592205 CDS YP_003057599.1 254779494 8208447 860807..864745 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 18410539, 18201978, 18199531, 18039108, 17368441, 11560962, 11560948; Product type m : membrane component; Vacuolating cytotoxin 864745 vacA 8208447 vacA Helicobacter pylori B38 Vacuolating cytotoxin YP_003057599.1 860807 D 592205 CDS YP_003057600.1 254779495 8209087 complement(864818..865585) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10802180, 1526456, 2254251; Product type t : transporter; ABC transporter ATP-binding protein; Iron(III) dicitrate ABC transporter ATP-binding protein 865585 fecE 8209087 fecE Helicobacter pylori B38 ABC transporter ATP-binding protein; Iron(III) dicitrate ABC transporter ATP-binding protein YP_003057600.1 864818 R 592205 CDS YP_003057601.1 254779496 8208504 complement(865585..866565) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16484186, 14726233, 12896998, 12533448, 11123699, 1482271; Product type t : transporter; ABC transporter permease; Iron(III) dicitrate transport system permease protein FecD; membrane protein 866565 fecD 8208504 fecD Helicobacter pylori B38 ABC transporter permease; Iron(III) dicitrate transport system permease protein FecD; membrane protein YP_003057601.1 865585 R 592205 CDS YP_003057602.1 254779497 8208503 complement(866558..867412) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9139899; Product type pe : enzyme; short-chain oxidoreductase 867412 8208503 HELPY_0875 Helicobacter pylori B38 short-chain oxidoreductase YP_003057602.1 866558 R 592205 CDS YP_003057603.1 254779498 8207963 867552..868076 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9139899; Product type pe : enzyme; acyl coenzyme A thioesterase 868076 8207963 HELPY_0876 Helicobacter pylori B38 acyl coenzyme A thioesterase YP_003057603.1 867552 D 592205 CDS YP_003057604.1 254779499 8207964 complement(868436..868747) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 868747 8207964 HELPY_0877 Helicobacter pylori B38 hypothetical protein YP_003057604.1 868436 R 592205 CDS YP_003057605.1 254779500 8207965 complement(868825..869091) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 869091 8207965 HELPY_0878 Helicobacter pylori B38 hypothetical protein YP_003057605.1 868825 R 592205 CDS YP_003057606.1 254779501 8207966 complement(869072..869449) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 869449 8207966 HELPY_0879 Helicobacter pylori B38 hypothetical protein YP_003057606.1 869072 R 592205 CDS YP_003057607.1 254779502 8207967 complement(869745..871985) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16790815, 16322107, 15557006, 14762173, 11866522, 11160014, 9430586; Product type pm : membrane component; Adhesin 871985 babA 8207967 babA Helicobacter pylori B38 Adhesin YP_003057607.1 869745 R 592205 CDS YP_003057609.1 254779503 8208340 complement(873030..874142) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 16814778, 15504408, 11123699, 1482271; Product type f : factor; Hydrogenase expression/formation protein HypD 874142 hypD 8208340 hypD Helicobacter pylori B38 Hydrogenase expression/formation protein HypD YP_003057609.1 873030 R 592205 CDS YP_003057610.1 254779504 8208703 complement(874160..874396) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 15504408, 15491154, 10783387, 1482271; Product type f : factor; Hydrogenase expression/formation protein (HUPF/HYPC) 874396 hypC 8208703 hypC Helicobacter pylori B38 Hydrogenase expression/formation protein (HUPF/HYPC) YP_003057610.1 874160 R 592205 CDS YP_003057611.1 254779505 8208702 complement(874396..875124) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 14521881, 1289699, 16807243, 16142921, 12533448, 11123699; Product type e : enzyme; Hydrogenase and urease maturation protein 875124 hypB 8208702 hypB Helicobacter pylori B38 Hydrogenase and urease maturation protein YP_003057611.1 874396 R 592205 CDS YP_003057612.1 254779506 8208701 complement(875233..875358) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 875358 8208701 HELPY_0885 Helicobacter pylori B38 hypothetical protein YP_003057612.1 875233 R 592205 CDS YP_003057613.1 254779507 8207968 complement(875369..875668) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 875668 8207968 HELPY_0886 Helicobacter pylori B38 hypothetical protein YP_003057613.1 875369 R 592205 CDS YP_003057614.1 254779508 8207971 complement(876982..878538) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16678422, 16552088, 15062079, 15048838; Product type e : enzyme; phosphotransacetylase 878538 pta 8207971 pta Helicobacter pylori B38 phosphotransacetylase YP_003057614.1 876982 R 592205 CDS YP_003057615.1 254779509 8208883 878919..880457 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8631687; Product type pf : factor; flagellar control protein 880457 8208883 HELPY_0890 Helicobacter pylori B38 flagellar control protein YP_003057615.1 878919 D 592205 CDS YP_003057616.1 254779510 8207972 880508..881428 1 NC_012973.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 881428 flgD 8207972 flgD Helicobacter pylori B38 flagellar basal body rod modification protein YP_003057616.1 880508 D 592205 CDS YP_003057617.1 254779511 8208518 881425..883242 1 NC_012973.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 883242 flgE 8208518 flgE Helicobacter pylori B38 flagellar hook protein FlgE YP_003057617.1 881425 D 592205 CDS YP_003057618.1 254779512 8208520 883294..883875 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310; Product type pe : enzyme; type II restriction endonuclease Hpy8I 883875 8208520 HELPY_0893 Helicobacter pylori B38 type II restriction endonuclease Hpy8I YP_003057618.1 883294 D 592205 CDS YP_003057619.1 254779513 8207973 883897..885036 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11226310; Product type e : enzyme; type II m6A methylase 885036 hpy8IM 8207973 hpy8IM Helicobacter pylori B38 type II m6A methylase YP_003057619.1 883897 D 592205 CDS YP_003057620.1 254779514 8208676 885040..887067 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16815905, 16442499, 15199167, 14757053, 10388562; Product type e : enzyme; ATP-dependent single-stranded DNA helicase 887067 8208676 HELPY_0895 Helicobacter pylori B38 ATP-dependent single-stranded DNA helicase YP_003057620.1 885040 D 592205 CDS YP_003057621.1 254779515 8207974 887654..889207 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856, 12399485, 11925614, 7534278; Product type m : membrane component; outer membrane porin and adhesin HopC 889207 hopC 8207974 hopC Helicobacter pylori B38 outer membrane porin and adhesin HopC YP_003057621.1 887654 D 592205 CDS YP_003057622.1 254779516 8208650 889229..890827 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12399485, 7534278, 16322107, 16173498, 15918181, 12454856, 11925614; Product type m : membrane component; outer membrane porin and adhesin HopB 890827 hopB 8208650 hopB Helicobacter pylori B38 outer membrane porin and adhesin HopB YP_003057622.1 889229 D 592205 CDS YP_003057623.1 254779517 8208649 complement(891701..893245) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein 893245 8208649 HELPY_0900 Helicobacter pylori B38 outer membrane protein YP_003057623.1 891701 R 592205 CDS YP_003057624.1 254779518 8207975 complement(893571..896012) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12704139, 12165031, 11886560, 16914236, 16797200, 11953376; Product type pt : transporter; Iron-regulated outer membrane protein 896012 frpB2 8207975 frpB2 Helicobacter pylori B38 Iron-regulated outer membrane protein YP_003057624.1 893571 R 592205 CDS YP_003057625.1 254779519 8208558 complement(896196..896627) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 896627 8208558 HELPY_0902 Helicobacter pylori B38 hypothetical protein YP_003057625.1 896196 R 592205 CDS YP_003057626.1 254779520 8207976 complement(896632..899889) 1 NC_012973.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 899889 carB 8207976 carB Helicobacter pylori B38 carbamoyl phosphate synthase large subunit YP_003057626.1 896632 R 592205 CDS YP_003057627.1 254779521 8208890 complement(899987..900679) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein 900679 8208890 HELPY_0904 Helicobacter pylori B38 hypothetical protein YP_003057627.1 899987 R 592205 CDS YP_003057628.1 254779522 8207977 900826..901824 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16523451; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase 901824 gap1 8207977 gap1 Helicobacter pylori B38 glyceraldehyde-3-phosphate dehydrogenase YP_003057628.1 900826 D 592205 CDS YP_003057629.1 254779523 8208576 901905..909479 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16610017, 16579839, 16579837, 16552038, 16497614, 16489309; Product type pf : factor; toxin-like outer membrane protein/vacuolating cytotoxin VacA 909479 8208576 HELPY_0906 Helicobacter pylori B38 toxin-like outer membrane protein/vacuolating cytotoxin VacA YP_003057629.1 901905 D 592205 CDS YP_003057630.1 254779524 8207978 909531..910625 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16220040, 16173498, 15918181, 12454856, 11211867, 9252185; Product type m : membrane component; outer membrane protein HopK 910625 hopK 8207978 hopK Helicobacter pylori B38 outer membrane protein HopK YP_003057630.1 909531 D 592205 CDS YP_003057631.1 254779525 8208658 complement(910693..910899) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16405343, 1732207, 7966298; Product type e : enzyme; tautomerase, DmpI-related protein 910899 8208658 HELPY_0908 Helicobacter pylori B38 tautomerase, DmpI-related protein YP_003057631.1 910693 R 592205 CDS YP_003057632.1 254779526 8207979 911056..911637 1 NC_012973.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 911637 recR 8207979 recR Helicobacter pylori B38 recombination protein RecR YP_003057632.1 911056 D 592205 CDS YP_003057633.1 254779527 8208909 911634..912779 1 NC_012973.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 912779 truD 8208909 truD Helicobacter pylori B38 tRNA pseudouridine synthase D YP_003057633.1 911634 D 592205 CDS YP_003057634.1 254779528 8209059 912766..913698 1 NC_012973.1 metalloprotease; heat shock protein HtpX 913698 8209059 HELPY_0911 Helicobacter pylori B38 heat shock protein HtpX YP_003057634.1 912766 D 592205 CDS YP_003057635.1 254779529 8207980 913699..914241 1 NC_012973.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 914241 folE 8207980 folE Helicobacter pylori B38 GTP cyclohydrolase I YP_003057635.1 913699 D 592205 CDS YP_003057636.1 254779530 8208551 914257..915168 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15809342, 15236249, 8830250, 2089044, 2676985; Product type e : enzyme; geranyltranstransferase 915168 ispA 8208551 ispA Helicobacter pylori B38 geranyltranstransferase YP_003057636.1 914257 D 592205 CDS YP_003057637.1 254779531 8208715 915165..915968 1 NC_012973.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 915968 surE 8208715 surE Helicobacter pylori B38 stationary phase survival protein SurE YP_003057637.1 915165 D 592205 CDS YP_003057638.1 254779532 8209021 915965..916624 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 916624 8209021 HELPY_0915 Helicobacter pylori B38 hypothetical protein YP_003057638.1 915965 D 592205 CDS YP_003057639.1 254779533 8207981 916626..917228 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 917228 8207981 HELPY_0916 Helicobacter pylori B38 hypothetical protein YP_003057639.1 916626 D 592205 CDS YP_003057640.1 254779534 8207982 917231..917986 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 917986 8207982 HELPY_0917 Helicobacter pylori B38 hypothetical protein YP_003057640.1 917231 D 592205 CDS YP_003057641.1 254779535 8207983 918083..918568 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 918568 8207983 HELPY_0918 Helicobacter pylori B38 hypothetical protein YP_003057641.1 918083 D 592205 CDS YP_003057642.1 254779536 8207989 complement(921987..922376) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 922376 8207989 HELPY_0924 Helicobacter pylori B38 hypothetical protein YP_003057642.1 921987 R 592205 CDS YP_003057643.1 254779537 8207990 complement(922444..923133) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter permease 923133 8207990 HELPY_0925 Helicobacter pylori B38 ABC transporter permease YP_003057643.1 922444 R 592205 CDS YP_003057644.1 254779538 8207991 complement(923141..923902) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC-type transport system, periplasmic binding protein 923902 8207991 HELPY_0926 Helicobacter pylori B38 ABC-type transport system, periplasmic binding protein YP_003057644.1 923141 R 592205 CDS YP_003057645.1 254779539 8207992 complement(923970..925103) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15683232, 9063881, 16310730; Product type e : enzyme; alanine racemase 925103 alr 8207992 alr Helicobacter pylori B38 alanine racemase YP_003057645.1 923970 R 592205 CDS YP_003057646.1 254779540 8208373 complement(925110..926462) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1447975, 1400476, 8031825; Product type pt : transporter; amino acid transporter; membrane protein 926462 8208373 HELPY_0928 Helicobacter pylori B38 amino acid transporter; membrane protein YP_003057646.1 925110 R 592205 CDS YP_003057647.1 254779541 8207993 complement(926503..927735) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9457858, 7906689; Product type pe : enzyme; D-amino acid dehydrogenase 927735 8207993 HELPY_0929 Helicobacter pylori B38 D-amino acid dehydrogenase YP_003057647.1 926503 R 592205 CDS YP_003057648.1 254779542 8207994 complement(927758..928135) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10368157, 10557275; Product type pr : regulator; translation initiation inhibitor 928135 8207994 HELPY_0930 Helicobacter pylori B38 translation initiation inhibitor YP_003057648.1 927758 R 592205 CDS YP_003057649.1 254779543 8208357 929062..930543 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15228539, 16021482, 9190799; Product type pt : transporter; cation antiporter; membrane protein 930543 8208357 HELPY_0931 Helicobacter pylori B38 cation antiporter; membrane protein YP_003057649.1 929062 D 592205 CDS YP_003057650.1 254779544 8207996 930869..931231 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 931231 8207996 HELPY_0932 Helicobacter pylori B38 hypothetical protein YP_003057650.1 930869 D 592205 CDS YP_003057651.1 254779545 8207997 complement(931437..931592) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 931592 8207997 HELPY_0933 Helicobacter pylori B38 hypothetical protein YP_003057651.1 931437 R 592205 CDS YP_003057652.1 254779546 8207998 complement(931635..932648) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 932648 8207998 HELPY_0934 Helicobacter pylori B38 hypothetical protein YP_003057652.1 931635 R 592205 CDS YP_003057653.1 254779547 8207999 complement(932658..933110) 1 NC_012973.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 933110 8207999 HELPY_0935 Helicobacter pylori B38 rRNA large subunit methyltransferase YP_003057653.1 932658 R 592205 CDS YP_003057654.1 254779548 8208000 complement(933124..933993) 1 NC_012973.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 933993 accD 8208000 accD Helicobacter pylori B38 acetyl-CoA carboxylase subunit beta YP_003057654.1 933124 R 592205 CDS YP_003057655.1 254779549 8208364 934074..934688 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; recombination protein RecO 934688 8208364 HELPY_0937 Helicobacter pylori B38 recombination protein RecO YP_003057655.1 934074 D 592205 CDS YP_003057656.1 254779550 8208001 934699..935355 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7538190; Product type pf : factor; competence/damage-inducible protein CinA 935355 8208001 HELPY_0938 Helicobacter pylori B38 competence/damage-inducible protein CinA YP_003057656.1 934699 D 592205 CDS YP_003057657.1 254779551 8208002 complement(935358..935924) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 935924 8208002 HELPY_0939 Helicobacter pylori B38 hypothetical protein YP_003057657.1 935358 R 592205 CDS YP_003057658.1 254779552 8208003 complement(935989..936621) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16426819, 15904482, 15856372, 15496391, 15361078, 12738391, 12648728; Product type e : enzyme; NAD(P)H-dependent nitroreductase 936621 rdxA 8208003 rdxA Helicobacter pylori B38 NAD(P)H-dependent nitroreductase YP_003057658.1 935989 R 592205 CDS YP_003057659.1 254779553 8208904 complement(936618..937472) 1 NC_012973.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 937472 lgt 8208904 lgt Helicobacter pylori B38 prolipoprotein diacylglyceryl transferase YP_003057659.1 936618 R 592205 CDS YP_003057660.1 254779554 8208730 complement(937482..938210) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15078091, 9660827, 9843401; Product type e : enzyme; Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) 938210 rluC 8208730 rluC Helicobacter pylori B38 Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) YP_003057660.1 937482 R 592205 CDS YP_003057661.1 254779555 8208925 complement(938229..939410) 1 NC_012973.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 939410 waaA 8208925 waaA Helicobacter pylori B38 3-deoxy-D-manno-octulosonic-acid transferase YP_003057661.1 938229 R 592205 CDS YP_003057662.1 254779556 8209089 complement(939411..940190) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 940190 8209089 HELPY_0944 Helicobacter pylori B38 hypothetical protein YP_003057662.1 939411 R 592205 CDS YP_003057663.1 254779557 8208004 complement(940200..940931) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 940931 8208004 HELPY_0945 Helicobacter pylori B38 hypothetical protein YP_003057663.1 940200 R 592205 CDS YP_003057664.1 254779558 8208005 complement(940933..941829) 1 NC_012973.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 941829 glyQ 8208005 glyQ Helicobacter pylori B38 glycyl-tRNA synthetase subunit alpha YP_003057664.1 940933 R 592205 CDS YP_003057665.1 254779559 8208594 complement(941843..942781) 1 NC_012973.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 942781 gpsA 8208594 gpsA Helicobacter pylori B38 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_003057665.1 941843 R 592205 CDS YP_003057666.1 254779560 8208602 complement(942913..943209) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15113832, 14536035; Product type c : carrier; Acyl carrier protein (ACP) 943209 acpP2 8208602 acpP2 Helicobacter pylori B38 Acyl carrier protein (ACP) YP_003057666.1 942913 R 592205 CDS YP_003057667.1 254779561 8208367 complement(943277..945214) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATPase 945214 8208367 HELPY_0949 Helicobacter pylori B38 ATPase YP_003057667.1 943277 R 592205 CDS YP_003057668.1 254779562 8208011 complement(949605..949886) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 949886 8208011 HELPY_0955 Helicobacter pylori B38 hypothetical protein YP_003057668.1 949605 R 592205 CDS YP_003057669.1 254779563 8208012 complement(949902..952964) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426358, 11023484, 10473554, 9371429, 8991852, 8829543; Product type pt : transporter; cobalt-zinc-cadmium resistance protein, CzcA family; membrane protein 952964 8208012 HELPY_0956 Helicobacter pylori B38 cobalt-zinc-cadmium resistance protein, CzcA family; membrane protein YP_003057669.1 949902 R 592205 CDS YP_003057670.1 254779564 8208013 complement(952961..954040) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426358, 9371429, 8991852; Product type pt : transporter; cobalt-zinc-cadmium resistance protein, CzcB family 954040 8208013 HELPY_0957 Helicobacter pylori B38 cobalt-zinc-cadmium resistance protein, CzcB family YP_003057670.1 952961 R 592205 CDS YP_003057671.1 254779565 8208014 complement(954037..955335) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 955335 8208014 HELPY_0958 Helicobacter pylori B38 hypothetical protein YP_003057671.1 954037 R 592205 CDS YP_003057672.1 254779566 8208015 complement(955325..957430) 1 NC_012973.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 957430 glyS 8208015 glyS Helicobacter pylori B38 glycyl-tRNA synthetase subunit beta YP_003057672.1 955325 R 592205 CDS YP_003057673.1 254779567 8208595 957543..958661 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 958661 8208595 HELPY_0960 Helicobacter pylori B38 hypothetical protein YP_003057673.1 957543 D 592205 CDS YP_003057674.1 254779568 8208016 958674..960149 1 NC_012973.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 960149 gpmI 8208016 gpmI Helicobacter pylori B38 phosphoglyceromutase YP_003057674.1 958674 D 592205 CDS YP_003057675.1 254779569 8208600 960164..960445 1 NC_012973.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 960445 gatC 8208600 gatC Helicobacter pylori B38 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_003057675.1 960164 D 592205 CDS YP_003057676.1 254779570 8208579 complement(960541..961860) 1 NC_012973.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 961860 bioA 8208579 bioA Helicobacter pylori B38 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_003057676.1 960541 R 592205 CDS YP_003057677.1 254779571 8208404 961990..963453 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16267292, 9670013; Product type pe : enzyme; pedidyl-prolyl cis-trans ismerase D 963453 8208404 HELPY_0964 Helicobacter pylori B38 pedidyl-prolyl cis-trans ismerase D YP_003057677.1 961990 D 592205 CDS YP_003057678.1 254779572 8208017 963468..964949 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12626683, 16159787, 11847116, 11053380, 1400163; Product type cp : cell process; Cell division protein ftsA 964949 ftsA 8208017 ftsA Helicobacter pylori B38 Cell division protein ftsA YP_003057678.1 963468 D 592205 CDS YP_003057679.1 254779573 8208562 965074..966237 1 NC_012973.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 966237 ftsZ 8208562 ftsZ Helicobacter pylori B38 cell division protein FtsZ YP_003057679.1 965074 D 592205 CDS YP_003057680.1 254779574 8208567 complement(967112..967303) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 967303 8208567 HELPY_0971 Helicobacter pylori B38 hypothetical protein YP_003057680.1 967112 R 592205 CDS YP_003057681.1 254779575 8208018 967380..967676 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7674922; Product type pe : enzyme; metallopeptidase 967676 8208018 HELPY_0973 Helicobacter pylori B38 metallopeptidase YP_003057681.1 967380 D 592205 CDS YP_003057682.1 254779576 8208019 967669..967923 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10856643, 3021756; Product type pe : enzyme; exonuclease VII, large subunit 967923 8208019 HELPY_0974 Helicobacter pylori B38 exonuclease VII, large subunit YP_003057682.1 967669 D 592205 CDS YP_003057683.1 254779577 8208321 968424..969248 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15063854, 14671322, 12626684, 12080120, 10202137, 2546007; Product type pt : transporter; small-conductance mechanosensitive channel; membrane protein 969248 8208321 HELPY_0976 Helicobacter pylori B38 small-conductance mechanosensitive channel; membrane protein YP_003057683.1 968424 D 592205 CDS YP_003057684.1 254779578 8208021 969535..969750 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 969750 8208021 HELPY_0977 Helicobacter pylori B38 hypothetical protein YP_003057684.1 969535 D 592205 CDS YP_003057685.1 254779579 8208031 complement(976664..976948) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 976948 8208031 HELPY_0987 Helicobacter pylori B38 hypothetical protein YP_003057685.1 976664 R 592205 CDS YP_003057686.1 254779580 8208032 complement(977059..977193) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 977193 8208032 HELPY_0988 Helicobacter pylori B38 hypothetical protein YP_003057686.1 977059 R 592205 CDS YP_003057687.1 254779581 8208033 complement(977190..980792) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 980792 8208033 HELPY_0989 Helicobacter pylori B38 hypothetical protein YP_003057687.1 977190 R 592205 CDS YP_003057688.1 254779582 8208034 complement(980786..982135) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; serine/threonine kinase 982135 8208034 HELPY_0990 Helicobacter pylori B38 serine/threonine kinase YP_003057688.1 980786 R 592205 CDS YP_003057689.1 254779583 8208037 complement(982809..983111) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 983111 8208037 HELPY_0993 Helicobacter pylori B38 hypothetical protein YP_003057689.1 982809 R 592205 CDS YP_003057690.1 254779584 8208038 complement(983229..983873) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 983873 8208038 HELPY_0994 Helicobacter pylori B38 hypothetical protein YP_003057690.1 983229 R 592205 CDS YP_003057691.1 254779585 8208039 984215..984358 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 984358 8208039 HELPY_0996 Helicobacter pylori B38 hypothetical protein YP_003057691.1 984215 D 592205 CDS YP_003057692.1 254779586 8208318 988415..988642 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 988642 8208318 HELPY_1000 Helicobacter pylori B38 hypothetical protein YP_003057692.1 988415 D 592205 CDS YP_003057693.1 254779587 8208041 988695..990410 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 990410 8208041 HELPY_1001 Helicobacter pylori B38 hypothetical protein YP_003057693.1 988695 D 592205 CDS YP_003057694.1 254779588 8208042 990482..991810 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 991810 8208042 HELPY_1002 Helicobacter pylori B38 hypothetical protein YP_003057694.1 990482 D 592205 CDS YP_003057695.1 254779589 8208043 991777..993636 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 993636 8208043 HELPY_1003 Helicobacter pylori B38 hypothetical protein YP_003057695.1 991777 D 592205 CDS YP_003057696.1 254779590 8208046 complement(994801..996648) 1 NC_012973.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 996648 speA 8208046 speA Helicobacter pylori B38 arginine decarboxylase YP_003057696.1 994801 R 592205 CDS YP_003057697.1 254779591 8209016 complement(996663..997832) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7961465; Product type pe : enzyme; polysaccharide biosynthesis protein 997832 8209016 HELPY_1007 Helicobacter pylori B38 polysaccharide biosynthesis protein YP_003057697.1 996663 R 592205 CDS YP_003057698.1 254779592 8208047 complement(997837..998265) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 998265 8208047 HELPY_1008 Helicobacter pylori B38 hypothetical protein YP_003057698.1 997837 R 592205 CDS YP_003057699.1 254779593 8208048 complement(998280..999065) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 999065 8208048 HELPY_1009 Helicobacter pylori B38 hypothetical protein YP_003057699.1 998280 R 592205 CDS YP_003057700.1 254779594 8208049 complement(999069..1000076) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 1000076 8208049 HELPY_1010 Helicobacter pylori B38 hypothetical protein YP_003057700.1 999069 R 592205 CDS YP_003057701.1 254779595 8208050 complement(1000076..1002028) 1 NC_012973.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1002028 metS 8208050 metS Helicobacter pylori B38 methionyl-tRNA synthetase YP_003057701.1 1000076 R 592205 CDS YP_003057702.1 254779596 8208755 1002197..1003366 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20353464, 9882672, 8022273, 93075691; Product type e : enzyme; cyclopropane-fatty-acyl-phospholipid synthase 1003366 cfa 8208755 cfa Helicobacter pylori B38 cyclopropane-fatty-acyl-phospholipid synthase YP_003057702.1 1002197 D 592205 CDS YP_003057703.1 254779597 8208418 complement(1003376..1005247) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1005247 8208418 HELPY_1013 Helicobacter pylori B38 hypothetical protein YP_003057703.1 1003376 R 592205 CDS YP_003057704.1 254779598 8208336 complement(1006470..1007219) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97431527, 93139035, 96042077, 93253769; Product type ps : structure; neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin); signal peptide 1007219 8208336 HELPY_1014 Helicobacter pylori B38 neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin); signal peptide YP_003057704.1 1006470 R 592205 CDS YP_003057705.1 254779599 8208052 complement(1007303..1008829) 1 NC_012973.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1008829 guaA 8208052 guaA Helicobacter pylori B38 GMP synthase YP_003057705.1 1007303 R 592205 CDS YP_003057706.1 254779600 8208609 complement(1008840..1009331) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1009331 8208609 HELPY_1016 Helicobacter pylori B38 hypothetical protein YP_003057706.1 1008840 R 592205 CDS YP_003057707.1 254779601 8208053 complement(1009505..1011895) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15601707, 8919859, 2180922, 9242907, 8890912; Product type e : enzyme; biotin sulfoxide reductase 1011895 bisC 8208053 bisC Helicobacter pylori B38 biotin sulfoxide reductase YP_003057707.1 1009505 R 592205 CDS YP_003057708.1 254779602 8208410 complement(1011999..1012589) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1012589 8208410 HELPY_1019 Helicobacter pylori B38 hypothetical protein YP_003057708.1 1011999 R 592205 CDS YP_003057709.1 254779603 8208054 complement(1012615..1013937) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; cysteine desulfurase 1013937 8208054 HELPY_1020 Helicobacter pylori B38 cysteine desulfurase YP_003057709.1 1012615 R 592205 CDS YP_003057710.1 254779604 8208055 complement(1013956..1014270) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15703176, 1472710; Product type pe : enzyme; hydrolase 1014270 8208055 HELPY_1021 Helicobacter pylori B38 hydrolase YP_003057710.1 1013956 R 592205 CDS YP_003057711.1 254779605 8208056 1014351..1015337 1 NC_012973.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1015337 pheS 8208056 pheS Helicobacter pylori B38 phenylalanyl-tRNA synthetase subunit alpha YP_003057711.1 1014351 D 592205 CDS YP_003057712.1 254779606 8208858 1015337..1017631 1 NC_012973.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1017631 pheT 8208858 pheT Helicobacter pylori B38 phenylalanyl-tRNA synthetase subunit beta YP_003057712.1 1015337 D 592205 CDS YP_003057713.1 254779607 8208859 1017647..1018936 1 NC_012973.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1018936 aroA 8208859 aroA Helicobacter pylori B38 3-phosphoshikimate 1-carboxyvinyltransferase YP_003057713.1 1017647 D 592205 CDS YP_003057714.1 254779608 8208380 1018926..1019750 1 NC_012973.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1019750 ispH 8208380 ispH Helicobacter pylori B38 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_003057714.1 1018926 D 592205 CDS YP_003057715.1 254779609 8208720 1019871..1021541 1 NC_012973.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1021541 rpsA 8208720 rpsA Helicobacter pylori B38 30S ribosomal protein S1 YP_003057715.1 1019871 D 592205 CDS YP_003057716.1 254779610 8208975 1021570..1022121 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1022121 8208975 HELPY_1027 Helicobacter pylori B38 hypothetical protein YP_003057716.1 1021570 D 592205 CDS YP_003057717.1 254779611 8208057 1022137..1023711 1 NC_012973.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1023711 serA 8208057 serA Helicobacter pylori B38 D-3-phosphoglycerate dehydrogenase YP_003057717.1 1022137 D 592205 CDS YP_003057718.1 254779612 8209010 1023721..1025571 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15979273, 12799002, 11029449, 782527; Product type e : enzyme; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1025571 ubiD 8209010 ubiD Helicobacter pylori B38 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_003057718.1 1023721 D 592205 CDS YP_003057719.1 254779613 8209071 1025581..1026249 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1026249 8209071 HELPY_1030 Helicobacter pylori B38 hypothetical protein YP_003057719.1 1025581 D 592205 CDS YP_003057720.1 254779614 8208058 1026251..1027009 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1027009 8208058 HELPY_1031 Helicobacter pylori B38 hypothetical protein YP_003057720.1 1026251 D 592205 CDS YP_003057721.1 254779615 8208059 1027013..1027948 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16207913, 11535789, 16369945, 8809743, 8169224, 8169223; Product type r : regulator; Chemotaxis protein CheV 1027948 cheV3 8208059 cheV3 Helicobacter pylori B38 Chemotaxis protein CheV YP_003057721.1 1027013 D 592205 CDS YP_003057722.1 254779616 8208422 1028004..1030451 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16879644, 16207913, 15664919, 10722597, 9724541; Product type e : enzyme; Chemotaxis protein cheA 1030451 cheA 8208422 cheA Helicobacter pylori B38 Chemotaxis protein cheA YP_003057722.1 1028004 D 592205 CDS YP_003057723.1 254779617 8208419 1030448..1030945 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16207913, 11535789, 16369945, 1326408, 8809743, 8456299; Product type r : regulator; Chemotaxis protein CheW 1030945 cheW 8208419 cheW Helicobacter pylori B38 Chemotaxis protein CheW YP_003057723.1 1030448 D 592205 CDS YP_003057724.1 254779618 8208423 complement(1031205..1031705) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11744405, 15158282, 11673441, 9457886, 7523254; Product type e : enzyme; thiol peroxidase 1031705 tpx 8208423 tpx Helicobacter pylori B38 thiol peroxidase YP_003057724.1 1031205 R 592205 CDS YP_003057725.1 254779619 8209048 1031928..1032569 1 NC_012973.1 [Fe]; Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15901691, 16416177, 10675591, 7515365, 8225605; Product type e : enzyme; Superoxide dismutase 1032569 sodB 8209048 sodB Helicobacter pylori B38 Superoxide dismutase YP_003057725.1 1031928 D 592205 CDS YP_003057726.1 254779620 8209015 1032621..1033352 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1033352 8209015 HELPY_1037 Helicobacter pylori B38 hypothetical protein YP_003057726.1 1032621 D 592205 CDS YP_003057727.1 254779621 8208060 complement(1033386..1035245) 1 NC_012973.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1035245 priA 8208060 priA Helicobacter pylori B38 primosome assembly protein PriA YP_003057727.1 1033386 R 592205 CDS YP_003057728.1 254779622 8208875 complement(1035230..1035466) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1035466 8208875 HELPY_1039 Helicobacter pylori B38 hypothetical protein YP_003057728.1 1035230 R 592205 CDS YP_003057729.1 254779623 8208061 complement(1035479..1035709) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1035709 8208061 HELPY_1040 Helicobacter pylori B38 hypothetical protein YP_003057729.1 1035479 R 592205 CDS YP_003057730.1 254779624 8208062 1035888..1036634 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1036634 8208062 HELPY_1041 Helicobacter pylori B38 hypothetical protein YP_003057730.1 1035888 D 592205 CDS YP_003057731.1 254779625 8208063 complement(1036674..1037198) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1037198 8208063 HELPY_1042 Helicobacter pylori B38 hypothetical protein YP_003057731.1 1036674 R 592205 CDS YP_003057732.1 254779626 8208064 1037379..1038602 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metalloprotease; membrane protein 1038602 8208064 HELPY_1043 Helicobacter pylori B38 metalloprotease; membrane protein YP_003057732.1 1037379 D 592205 CDS YP_003057733.1 254779627 8208065 1038599..1039423 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15629922, 15223314, 11805295, 10690633, 10220893, 7883187; Product type e : enzyme; Modification methylase HemK 1039423 hemG 8208065 hemG Helicobacter pylori B38 Modification methylase HemK YP_003057733.1 1038599 D 592205 CDS YP_003057734.1 254779628 8208629 1039495..1040841 1 NC_012973.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1040841 gdhA 8208629 gdhA Helicobacter pylori B38 glutamate dehydrogenase YP_003057734.1 1039495 D 592205 CDS YP_003057735.1 254779629 8208580 complement(1040855..1042183) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16477004, 15058985, 10496917; Product type e : enzyme; Alpha1,3-fucosyltransferase 1042183 futA 8208580 futA Helicobacter pylori B38 Alpha1,3-fucosyltransferase YP_003057735.1 1040855 R 592205 CDS YP_003057736.1 254779630 8208571 complement(1042193..1045003) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16629661, 8617725; Product type f : factor; Cytochrome c biogenesis protein; membrane protein 1045003 ccsA 8208571 ccsA Helicobacter pylori B38 Cytochrome c biogenesis protein; membrane protein YP_003057736.1 1042193 R 592205 CDS YP_003057737.1 254779631 8208415 complement(1045012..1045683) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1045683 8208415 HELPY_1048 Helicobacter pylori B38 hypothetical protein YP_003057737.1 1045012 R 592205 CDS YP_003057738.1 254779632 8208066 complement(1045756..1046763) 1 NC_012973.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1046763 hemH 8208066 hemH Helicobacter pylori B38 ferrochelatase YP_003057738.1 1045756 R 592205 CDS YP_003057739.1 254779633 8208630 1046819..1047250 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1047250 8208630 HELPY_1050 Helicobacter pylori B38 hypothetical protein YP_003057739.1 1046819 D 592205 CDS YP_003057740.1 254779634 8208067 1047251..1047931 1 NC_012973.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1047931 8208067 HELPY_1051 Helicobacter pylori B38 16S ribosomal RNA methyltransferase RsmE YP_003057740.1 1047251 D 592205 CDS YP_003057741.1 254779635 8208068 complement(1048024..1050141) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1050141 8208068 HELPY_1052 Helicobacter pylori B38 hypothetical protein YP_003057741.1 1048024 R 592205 CDS YP_003057742.1 254779636 8208069 complement(1050300..1050866) 1 NC_012973.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1050866 dcd 8208069 dcd Helicobacter pylori B38 deoxycytidine triphosphate deaminase YP_003057742.1 1050300 R 592205 CDS YP_003057743.1 254779637 8208453 1050996..1051478 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11390406, 11157970, 10542197; Product type e : enzyme; biotin carboxyl carrier protein of acetyl-CoA carboxylase 1051478 accB 8208453 accB Helicobacter pylori B38 biotin carboxyl carrier protein of acetyl-CoA carboxylase YP_003057743.1 1050996 D 592205 CDS YP_003057744.1 254779638 8208362 1051484..1052851 1 NC_012973.1 biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1052851 accC 8208362 accC Helicobacter pylori B38 biotin carboxylase YP_003057744.1 1051484 D 592205 CDS YP_003057745.1 254779639 8208363 1052944..1053906 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17921292, 17346936, 11226310; Product type pe : enzyme; adenine methyltransferase 1053906 8208363 HELPY_1056 Helicobacter pylori B38 adenine methyltransferase YP_003057745.1 1052944 D 592205 CDS YP_003057746.1 254779640 8208070 1053903..1054454 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17346936, 16217547, 14711809, 12490707, 12426350, 12034832, 11956101; Product type pe : enzyme; type II restriction endonuclease 1054454 8208070 HELPY_1057 Helicobacter pylori B38 type II restriction endonuclease YP_003057746.1 1053903 D 592205 CDS YP_003057747.1 254779641 8208071 1054547..1055155 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1055155 8208071 HELPY_1058 Helicobacter pylori B38 hypothetical protein YP_003057747.1 1054547 D 592205 CDS YP_003057748.1 254779642 8208072 1055152..1056288 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16421095; Product type e : enzyme; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 1056288 pseC 8208072 pseC Helicobacter pylori B38 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_003057748.1 1055152 D 592205 CDS YP_003057749.1 254779643 8208334 1056599..1057624 1 NC_012973.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1057624 nrdF 8208334 nrdF Helicobacter pylori B38 ribonucleotide-diphosphate reductase subunit beta YP_003057749.1 1056599 D 592205 CDS YP_003057750.1 254779644 8208805 1057634..1058263 1 NC_012973.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1058263 pcm 8208805 pcm Helicobacter pylori B38 protein-L-isoaspartate O-methyltransferase YP_003057750.1 1057634 D 592205 CDS YP_003057751.1 254779645 8208842 1058274..1059311 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1059311 8208842 HELPY_1062 Helicobacter pylori B38 hypothetical protein YP_003057751.1 1058274 D 592205 CDS YP_003057752.1 254779646 8208073 1059312..1060040 1 NC_012973.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1060040 truA 8208073 truA Helicobacter pylori B38 tRNA pseudouridine synthase A YP_003057752.1 1059312 D 592205 CDS YP_003057753.1 254779647 8209058 complement(1060034..1061068) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14597172, 11425718, 11119535, 9708982; Product type e : enzyme; UDP-glucose 4-epimerase(Galactowaldenase) (UDP-galactose 4-epimerase) 1061068 galE 8209058 galE Helicobacter pylori B38 UDP-glucose 4-epimerase(Galactowaldenase) (UDP-galactose 4-epimerase) YP_003057753.1 1060034 R 592205 CDS YP_003057754.1 254779648 8208359 1061783..1063318 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1063318 8208359 HELPY_1065 Helicobacter pylori B38 hypothetical protein YP_003057754.1 1061783 D 592205 CDS YP_003057755.1 254779649 8208074 1063336..1064088 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase 1064088 8208074 HELPY_1066 Helicobacter pylori B38 short chain dehydrogenase YP_003057755.1 1063336 D 592205 CDS YP_003057756.1 254779650 8208075 complement(1064295..1065167) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16460007, 16040986, 15223324, 11777911, 99369890, 10748053; Product type cp : cell process; Cysteine-rich protein C 1065167 hcpC 8208075 hcpC Helicobacter pylori B38 Cysteine-rich protein C YP_003057756.1 1064295 R 592205 CDS YP_003057757.1 254779651 8208615 complement(1065242..1065862) 1 NC_012973.1 [4-hydroxy-2-oxoglutarate aldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxy-phosphogluconate aldolase (phospho-2-dehydro-3-deoxygluconate aldolase) (phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15659677, 12889025; Product type e : enzyme; multifunctional KHG/KDPG aldolase 1065862 eda 8208615 eda Helicobacter pylori B38 multifunctional KHG/KDPG aldolase YP_003057757.1 1065242 R 592205 CDS YP_003057758.1 254779652 8208481 complement(1065881..1067707) 1 NC_012973.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1067707 edd 8208481 edd Helicobacter pylori B38 phosphogluconate dehydratase YP_003057758.1 1065881 R 592205 CDS YP_003057759.1 254779653 8208482 1067774..1069051 1 NC_012973.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1069051 zwf 8208482 zwf Helicobacter pylori B38 glucose-6-phosphate 1-dehydrogenase YP_003057759.1 1067774 D 592205 CDS YP_003057760.1 254779654 8209095 1069062..1069745 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15766779; Product type pe : enzyme; 6-phosphogluconolactonase 1069745 pgl 8209095 pgl Helicobacter pylori B38 6-phosphogluconolactonase YP_003057760.1 1069062 D 592205 CDS YP_003057761.1 254779655 8208855 1069732..1070742 1 NC_012973.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1070742 glk 8208855 glk Helicobacter pylori B38 glucokinase YP_003057761.1 1069732 D 592205 CDS YP_003057762.1 254779656 8208585 1070903..1071949 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; zinc-containing alcohol dehydrogenase 1071949 8208585 HELPY_1073 Helicobacter pylori B38 zinc-containing alcohol dehydrogenase YP_003057762.1 1070903 D 592205 CDS YP_003057763.1 254779657 8208076 complement(1071961..1073256) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1624461; Product type pe : enzyme; lipopolysaccharide 1,3-galactosyltransferase 1073256 8208076 HELPY_1074 Helicobacter pylori B38 lipopolysaccharide 1,3-galactosyltransferase YP_003057763.1 1071961 R 592205 CDS YP_003057764.1 254779658 8208077 1073435..1074742 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1074742 8208077 HELPY_1075 Helicobacter pylori B38 hypothetical protein YP_003057764.1 1073435 D 592205 CDS YP_003057765.1 254779659 8208078 complement(1074749..1075411) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein HorH 1075411 8208078 HELPY_1076 Helicobacter pylori B38 outer membrane protein HorH YP_003057765.1 1074749 R 592205 CDS YP_003057766.1 254779660 8208079 1075689..1076249 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; pyruvate flavodoxin oxidoreductase subunit gamma 1076249 porG 8208079 porG Helicobacter pylori B38 pyruvate flavodoxin oxidoreductase subunit gamma YP_003057766.1 1075689 D 592205 CDS YP_003057767.1 254779661 8208866 1076265..1076657 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; pyruvate flavodoxin oxidoreductase subunit delta 1076657 porD 8208866 porD Helicobacter pylori B38 pyruvate flavodoxin oxidoreductase subunit delta YP_003057767.1 1076265 D 592205 CDS YP_003057768.1 254779662 8208865 1076667..1077890 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; pyruvate flavodoxin oxidoreductase subunit alpha 1077890 porA 8208865 porA Helicobacter pylori B38 pyruvate flavodoxin oxidoreductase subunit alpha YP_003057768.1 1076667 D 592205 CDS YP_003057769.1 254779663 8208863 1077903..1078847 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; Pyruvate synthase subunit porB 1078847 porB 8208863 porB Helicobacter pylori B38 Pyruvate synthase subunit porB YP_003057769.1 1077903 D 592205 CDS YP_003057770.1 254779664 8208864 1078957..1080279 1 NC_012973.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1080279 purB 8208864 purB Helicobacter pylori B38 adenylosuccinate lyase YP_003057770.1 1078957 D 592205 CDS YP_003057771.1 254779665 8208886 1080350..1081183 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein 1081183 8208886 HELPY_1083 Helicobacter pylori B38 outer membrane protein YP_003057771.1 1080350 D 592205 CDS YP_003057772.1 254779666 8208080 complement(1081194..1083170) 1 NC_012973.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1083170 uvrB 8208080 uvrB Helicobacter pylori B38 excinuclease ABC subunit B YP_003057772.1 1081194 R 592205 CDS YP_003057773.1 254779667 8209084 complement(1083211..1083861) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1083861 8209084 HELPY_1085 Helicobacter pylori B38 hypothetical protein YP_003057773.1 1083211 R 592205 CDS YP_003057774.1 254779668 8208083 complement(1087149..1087919) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10748053, 11777911, 9317022, 9596777; Product type pe : enzyme; hypothetical protein 1087919 hcpX 8208083 hcpX Helicobacter pylori B38 hypothetical protein YP_003057774.1 1087149 R 592205 CDS YP_003057775.1 254779669 8208620 complement(1088186..1089889) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15378780, 11349094, 10200957; Product type e : enzyme; gamma-glutamyltranspeptidase 1089889 ggt 8208620 ggt Helicobacter pylori B38 gamma-glutamyltranspeptidase YP_003057775.1 1088186 R 592205 CDS YP_003057776.1 254779670 8208581 complement(1090105..1091925) 1 NC_012973.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1091925 flgK 8208581 flgK Helicobacter pylori B38 flagellar hook-associated protein FlgK YP_003057776.1 1090105 R 592205 CDS YP_003057777.1 254779671 8208525 complement(1091927..1092361) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1092361 8208525 HELPY_1092 Helicobacter pylori B38 hypothetical protein YP_003057777.1 1091927 R 592205 CDS YP_003057778.1 254779672 8208084 complement(1092493..1093449) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14711809, 12034832, 11703661, 11226310, 11133936; Product type e : enzyme; type II cytosine specific DNA methyltransferase 1093449 hpyAVIIIM 8208084 hpyAVIIIM Helicobacter pylori B38 type II cytosine specific DNA methyltransferase YP_003057778.1 1092493 R 592205 CDS YP_003057779.1 254779673 8208683 complement(1093590..1093820) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11985711, 11489132; Product type f : factor; Anti-sigma 28 factor 1093820 flgM 8208683 flgM Helicobacter pylori B38 Anti-sigma 28 factor YP_003057779.1 1093590 R 592205 CDS YP_003057780.1 254779674 8208527 complement(1093857..1094063) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1094063 8208527 HELPY_1095 Helicobacter pylori B38 hypothetical protein YP_003057780.1 1093857 R 592205 CDS YP_003057781.1 254779675 8208085 complement(1094095..1094652) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15569666, 12100551; Product type pe : enzyme; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD 1094652 slyD 8208085 slyD Helicobacter pylori B38 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD YP_003057781.1 1094095 R 592205 CDS YP_003057782.1 254779676 8209013 complement(1094639..1095634) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1095634 8209013 HELPY_1097 Helicobacter pylori B38 hypothetical protein YP_003057782.1 1094639 R 592205 CDS YP_003057783.1 254779677 8208086 complement(1095642..1096181) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10515919, 8763621; Product type lp : lipoprotein; peptidoglycan-associated lipoprotein ; petide signal 1096181 palA 8208086 palA Helicobacter pylori B38 peptidoglycan-associated lipoprotein ; petide signal YP_003057783.1 1095642 R 592205 CDS YP_003057784.1 254779678 8208835 complement(1096248..1097501) 1 NC_012973.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1097501 tolB 8208835 tolB Helicobacter pylori B38 translocation protein TolB YP_003057784.1 1096248 R 592205 CDS YP_003057785.1 254779679 8209044 complement(1097498..1098319) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1098319 8209044 HELPY_1100 Helicobacter pylori B38 hypothetical protein YP_003057785.1 1097498 R 592205 CDS YP_003057786.1 254779680 8208087 complement(1098338..1098739) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; biopolymer transport protein ExbD/TolR 1098739 exbD1 8208087 exbD1 Helicobacter pylori B38 biopolymer transport protein ExbD/TolR YP_003057786.1 1098338 R 592205 CDS YP_003057787.1 254779681 8208490 complement(1098792..1099361) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; Biopolymer transport ExbB protein; membrane protein 1099361 exbB1 8208490 exbB1 Helicobacter pylori B38 Biopolymer transport ExbB protein; membrane protein YP_003057787.1 1098792 R 592205 CDS YP_003057788.1 254779682 8208487 complement(1099372..1099746) 1 NC_012973.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1099746 atpC 8208487 atpC Helicobacter pylori B38 F0F1 ATP synthase subunit epsilon YP_003057788.1 1099372 R 592205 CDS YP_003057789.1 254779683 8208395 complement(1099753..1101162) 1 NC_012973.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1101162 atpD 8208395 atpD Helicobacter pylori B38 F0F1 ATP synthase subunit beta YP_003057789.1 1099753 R 592205 CDS YP_003057790.1 254779684 8208396 complement(1101184..1102089) 1 NC_012973.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1102089 atpG 8208396 atpG Helicobacter pylori B38 F0F1 ATP synthase subunit gamma YP_003057790.1 1101184 R 592205 CDS YP_003057791.1 254779685 8208399 complement(1102104..1103615) 1 NC_012973.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1103615 atpA 8208399 atpA Helicobacter pylori B38 F0F1 ATP synthase subunit alpha YP_003057791.1 1102104 R 592205 CDS YP_003057792.1 254779686 8208393 complement(1103638..1104180) 1 NC_012973.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1104180 atpH 8208393 atpH Helicobacter pylori B38 F0F1 ATP synthase subunit delta YP_003057792.1 1103638 R 592205 CDS YP_003057793.1 254779687 8208400 complement(1104181..1104696) 1 NC_012973.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1104696 atpF 8208400 atpF Helicobacter pylori B38 F0F1 ATP synthase subunit B YP_003057793.1 1104181 R 592205 CDS YP_003057794.1 254779688 8208398 complement(1104700..1105134) 1 NC_012973.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 1105134 atpX 8208398 atpX Helicobacter pylori B38 F0F1 ATP synthase subunit B' YP_003057794.1 1104700 R 592205 CDS YP_003057795.1 254779689 8208401 complement(1105245..1106120) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10619014, 9506522; Product type pr : regulator; plasmid replication-partition related protein 1106120 8208401 HELPY_1110 Helicobacter pylori B38 plasmid replication-partition related protein YP_003057795.1 1105245 R 592205 CDS YP_003057796.1 254779690 8208088 complement(1106120..1106914) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522501, 11042157, 9701812; Product type pr : regulator; SpoOJ regulator 1106914 8208088 HELPY_1111 Helicobacter pylori B38 SpoOJ regulator YP_003057796.1 1106120 R 592205 CDS YP_003057797.1 254779691 8208089 complement(1106917..1107555) 1 NC_012973.1 [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase(Biotin--protein ligase)]; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1107555 birA 8208089 birA Helicobacter pylori B38 biotin--protein ligase YP_003057797.1 1106917 R 592205 CDS YP_003057798.1 254779692 8208409 complement(1107564..1108475) 1 NC_012973.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1108475 fmt 8208409 fmt Helicobacter pylori B38 methionyl-tRNA formyltransferase YP_003057798.1 1107564 R 592205 CDS YP_003057799.1 254779693 8208547 complement(1108499..1110772) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1110772 8208547 HELPY_1114 Helicobacter pylori B38 hypothetical protein YP_003057799.1 1108499 R 592205 CDS YP_003057800.1 254779694 8208090 complement(1110818..1112119) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1112119 8208090 HELPY_1115 Helicobacter pylori B38 hypothetical protein YP_003057800.1 1110818 R 592205 CDS YP_003057801.1 254779695 8208091 1112390..1112806 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1112806 8208091 HELPY_1116 Helicobacter pylori B38 hypothetical protein YP_003057801.1 1112390 D 592205 CDS YP_003057802.1 254779696 8208316 complement(1115376..1116167) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1116167 8208316 HELPY_1119 Helicobacter pylori B38 hypothetical protein YP_003057802.1 1115376 R 592205 CDS YP_003057803.1 254779697 8208093 complement(1116818..1117174) 1 NC_012973.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1117174 rplS 8208093 rplS Helicobacter pylori B38 50S ribosomal protein L19 YP_003057803.1 1116818 R 592205 CDS YP_003057804.1 254779698 8208955 complement(1117196..1117885) 1 NC_012973.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1117885 trmD 8208955 trmD Helicobacter pylori B38 tRNA (guanine-N(1)-)-methyltransferase YP_003057804.1 1117196 R 592205 CDS YP_003057805.1 254779699 8209049 complement(1117886..1118440) 1 NC_012973.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1118440 rimM 8209049 rimM Helicobacter pylori B38 16S rRNA-processing protein RimM YP_003057805.1 1117886 R 592205 CDS YP_003057806.1 254779700 8208923 complement(1118441..1118788) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; RNA-binding protein 1118788 8208923 HELPY_1124 Helicobacter pylori B38 RNA-binding protein YP_003057806.1 1118441 R 592205 CDS YP_003057807.1 254779701 8208094 complement(1118805..1119035) 1 NC_012973.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1119035 rpsP 8208094 rpsP Helicobacter pylori B38 30S ribosomal protein S16 YP_003057807.1 1118805 R 592205 CDS YP_003057808.1 254779702 8208990 complement(1119109..1120455) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11735405, 16343944, 16299512, 16005894; Product type f : factor; Signal recognition particle protein (SRP) 1120455 ffh 8208990 ffh Helicobacter pylori B38 Signal recognition particle protein (SRP) YP_003057808.1 1119109 R 592205 CDS YP_003057809.1 254779703 8208506 complement(1120471..1123095) 1 NC_012973.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1123095 valS 8208506 valS Helicobacter pylori B38 valyl-tRNA synthetase YP_003057809.1 1120471 R 592205 CDS YP_003057810.1 254779704 8209088 1123226..1123633 1 NC_012973.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1123633 8209088 HELPY_1128 Helicobacter pylori B38 flagellar assembly protein FliW YP_003057810.1 1123226 D 592205 CDS YP_003057811.1 254779705 8208095 1123644..1124705 1 NC_012973.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 1124705 murG 8208095 murG Helicobacter pylori B38 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_003057811.1 1123644 D 592205 CDS YP_003057812.1 254779706 8208789 1124814..1126898 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopI 1126898 hopI 8208789 hopI Helicobacter pylori B38 outer membrane protein HopI YP_003057812.1 1124814 D 592205 CDS YP_003057813.1 254779707 8208656 1126921..1130598 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopL 1130598 hopL 8208656 hopL Helicobacter pylori B38 outer membrane protein HopL YP_003057813.1 1126921 D 592205 CDS YP_003057814.1 254779708 8208660 1130611..1131384 1 NC_012973.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1131384 proC 8208660 proC Helicobacter pylori B38 pyrroline-5-carboxylate reductase YP_003057814.1 1130611 D 592205 CDS YP_003057815.1 254779709 8208877 1131411..1131944 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1656497, 6284712; Product type ph : phenotype; cAMP-induced cell filamentation protein 1131944 8208877 HELPY_1133 Helicobacter pylori B38 cAMP-induced cell filamentation protein YP_003057815.1 1131411 D 592205 CDS YP_003057816.1 254779710 8208096 complement(1132190..1132612) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; metalloprotease 1132612 8208096 HELPY_1134 Helicobacter pylori B38 metalloprotease YP_003057816.1 1132190 R 592205 CDS YP_003057817.1 254779711 8208097 complement(1132666..1133160) 1 NC_012973.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 1133160 fldA 8208097 fldA Helicobacter pylori B38 flavodoxin FldA YP_003057817.1 1132666 R 592205 CDS YP_003057818.1 254779712 8208515 complement(1133252..1133866) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 1133866 8208515 HELPY_1136 Helicobacter pylori B38 hypothetical protein YP_003057818.1 1133252 R 592205 CDS YP_003057819.1 254779713 8208098 1133967..1134158 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2536685; Product type pt : transporter; cation transport subunit for cbb3-type oxidase 1134158 8208098 HELPY_1137 Helicobacter pylori B38 cation transport subunit for cbb3-type oxidase YP_003057819.1 1133967 D 592205 CDS YP_003057820.1 254779714 8208099 1134184..1135155 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16597971, 16427080, 15358361, 15063614; Product type pe : enzyme; thioredoxin reductase 1135155 trxB 8208099 trxB Helicobacter pylori B38 thioredoxin reductase YP_003057820.1 1134184 D 592205 CDS YP_003057821.1 254779715 8209062 complement(1135162..1136322) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9529885; Product type pt : transporter; permease, MFS superfamily; membrane protein 1136322 8209062 HELPY_1139 Helicobacter pylori B38 permease, MFS superfamily; membrane protein YP_003057821.1 1135162 R 592205 CDS YP_003057822.1 254779716 8208100 1136386..1138023 1 NC_012973.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1138023 pgi 8208100 pgi Helicobacter pylori B38 glucose-6-phosphate isomerase YP_003057822.1 1136386 D 592205 CDS YP_003057823.1 254779717 8208853 1138329..1139744 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; Product type m : membrane component; outer membrane protein HofH 1139744 hofH 8208853 hofH Helicobacter pylori B38 outer membrane protein HofH YP_003057823.1 1138329 D 592205 CDS YP_003057824.1 254779718 8208642 complement(1140097..1142160) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17526692, 12867454, 91162636, 2521622, 1848300; Product type t : transporter; Carbon starvation protein A; membrane protein 1142160 cstA 8208642 cstA Helicobacter pylori B38 Carbon starvation protein A; membrane protein YP_003057824.1 1140097 R 592205 CDS YP_003057825.1 254779719 8208444 1142371..1143024 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3027504, 15795228; Product type t : transporter; ABC transporter permease; amino-acid transporter GlnP1 1143024 8208444 HELPY_1143 Helicobacter pylori B38 ABC transporter permease; amino-acid transporter GlnP1 YP_003057825.1 1142371 D 592205 CDS YP_003057826.1 254779720 8208101 1143027..1143698 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3027504, 15795228; Product type t : transporter; ABC transporter permease; amino-acid transporter GlnP2 1143698 8208101 HELPY_1144 Helicobacter pylori B38 ABC transporter permease; amino-acid transporter GlnP2 YP_003057826.1 1143027 D 592205 CDS YP_003057827.1 254779721 8208102 1143700..1144446 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15795228, 12010975, 8360165; Product type t : transporter; ABC transporter ATP-binding protein; glutamate/aspartate transport protein GlnQ 1144446 8208102 HELPY_1145 Helicobacter pylori B38 ABC transporter ATP-binding protein; glutamate/aspartate transport protein GlnQ YP_003057827.1 1143700 D 592205 CDS YP_003057828.1 254779722 8208103 1144465..1145328 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12010975, 9142743, 3027504; Product type t : transporter; ABC transporter substrate-binding protein 1145328 8208103 HELPY_1146 Helicobacter pylori B38 ABC transporter substrate-binding protein YP_003057828.1 1144465 D 592205 CDS YP_003057829.1 254779723 8208104 1145450..1146001 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1146001 8208104 HELPY_1147 Helicobacter pylori B38 hypothetical protein YP_003057829.1 1145450 D 592205 CDS YP_003057830.1 254779724 8208105 complement(1146223..1147446) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15050034, 8661924; Product type t : transporter; glucose/galactose transporter GluP 1147446 8208105 HELPY_1148 Helicobacter pylori B38 glucose/galactose transporter GluP YP_003057830.1 1146223 R 592205 CDS YP_003057831.1 254779725 8208106 complement(1147575..1148882) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease; membrane protein 1148882 8208106 HELPY_1149 Helicobacter pylori B38 permease; membrane protein YP_003057831.1 1147575 R 592205 CDS YP_003057832.1 254779726 8208107 complement(1149344..1151236) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16102915, 15939494, 14742532, 12454143, 16322107, 16173498, 15918181; Product type m : membrane component; outer membrane protein HopQ 1151236 hopQ 8208107 hopQ Helicobacter pylori B38 outer membrane protein HopQ YP_003057832.1 1149344 R 592205 CDS YP_003057833.1 254779727 8208664 complement(1152057..1152758) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511068, 12571059, 11444965, 11437593, 3299264; Product type e : enzyme; Purine nucleoside phosphorylase DeoD-type (PNP) 1152758 deoD 8208664 deoD Helicobacter pylori B38 Purine nucleoside phosphorylase DeoD-type (PNP) YP_003057833.1 1152057 R 592205 CDS YP_003057834.1 254779728 8208459 complement(1152755..1153996) 1 NC_012973.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1153996 deoB 8208459 deoB Helicobacter pylori B38 phosphopentomutase YP_003057834.1 1152755 R 592205 CDS YP_003057835.1 254779729 8208458 complement(1154008..1155264) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16177292, 15678184, 11065368, 8853292; Product type pt : transporter; transport protein, Concentrative Nucleoside transporter (CNT) family; membrane protein 1155264 8208458 HELPY_1153 Helicobacter pylori B38 transport protein, Concentrative Nucleoside transporter (CNT) family; membrane protein YP_003057835.1 1154008 R 592205 CDS YP_003057836.1 254779730 8208333 1155580..1156911 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug-efflux transporter; membrane protein 1156911 8208333 HELPY_1154 Helicobacter pylori B38 multidrug-efflux transporter; membrane protein YP_003057836.1 1155580 D 592205 CDS YP_003057837.1 254779731 8208109 1156932..1157693 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12012333; Product type pe : enzyme; PP-loop family ATPase 1157693 8208109 HELPY_1155 Helicobacter pylori B38 PP-loop family ATPase YP_003057837.1 1156932 D 592205 CDS YP_003057838.1 254779732 8208110 complement(1157702..1158853) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; NA+/H+ antiporter 1158853 8208110 HELPY_1156 Helicobacter pylori B38 NA+/H+ antiporter YP_003057838.1 1157702 R 592205 CDS YP_003057839.1 254779733 8208111 complement(1158879..1160258) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug resistance protein; membrane protein 1160258 8208111 HELPY_1157 Helicobacter pylori B38 multidrug resistance protein; membrane protein YP_003057839.1 1158879 R 592205 CDS YP_003057840.1 254779734 8208112 complement(1160419..1161594) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20138160; Product type pt : transporter; sugar efflux transporter 1161594 8208112 HELPY_1158 Helicobacter pylori B38 sugar efflux transporter YP_003057840.1 1160419 R 592205 CDS YP_003057841.1 254779735 8208113 1161866..1162609 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16539401, 16459077, 16202223, 9811652, 8673298; Product type e : enzyme; Alpha-carbonic anhydrase 1162609 cah 8208113 cah Helicobacter pylori B38 Alpha-carbonic anhydrase YP_003057841.1 1161866 D 592205 CDS YP_003057842.1 254779736 8208412 complement(1162839..1164008) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1164008 8208412 HELPY_1160 Helicobacter pylori B38 hypothetical protein YP_003057842.1 1162839 R 592205 CDS YP_003057843.1 254779737 8208114 complement(1164420..1165460) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12071715, 15300892, 15752328, 15313252, 12071715; Product type e : enzyme; Aspartate-semialdehyde dehydrogenase 1165460 asd 8208114 asd Helicobacter pylori B38 Aspartate-semialdehyde dehydrogenase YP_003057843.1 1164420 R 592205 CDS YP_003057844.1 254779738 8208387 complement(1165447..1166775) 1 NC_012973.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1166775 hisS 8208387 hisS Helicobacter pylori B38 histidyl-tRNA synthetase YP_003057844.1 1165447 R 592205 CDS YP_003057845.1 254779739 8208634 1166837..1167886 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12798993, 11208792, 9916106, 9831648; Product type e : enzyme; ADP-heptose--LPS-heptosyltransferase II 1167886 rfaF 8208634 rfaF Helicobacter pylori B38 ADP-heptose--LPS-heptosyltransferase II YP_003057845.1 1166837 D 592205 CDS YP_003057846.1 254779740 8208913 complement(1168069..1168344) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1168344 8208913 HELPY_1164 Helicobacter pylori B38 hypothetical protein YP_003057846.1 1168069 R 592205 CDS YP_003057847.1 254779741 8208115 1168563..1169552 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1447221, 10884227; Product type pe : enzyme; aldo-keto reductase 1169552 8208115 HELPY_1166 Helicobacter pylori B38 aldo-keto reductase YP_003057847.1 1168563 D 592205 CDS YP_003057848.1 254779742 8208116 complement(1170114..1172192) 1 NC_012973.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1172192 fusA 8208116 fusA Helicobacter pylori B38 elongation factor G YP_003057848.1 1170114 R 592205 CDS YP_003057849.1 254779743 8208570 complement(1172204..1172671) 1 NC_012973.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1172671 rpsG 8208570 rpsG Helicobacter pylori B38 30S ribosomal protein S7 YP_003057849.1 1172204 R 592205 CDS YP_003057850.1 254779744 8208981 complement(1172687..1173094) 1 NC_012973.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1173094 rpsL 8208981 rpsL Helicobacter pylori B38 30S ribosomal protein S12 YP_003057850.1 1172687 R 592205 CDS YP_003057851.1 254779745 8208986 complement(1173183..1181855) 1 NC_012973.1 [DNA-directed RNA polymerase subunit beta (transcriptase subunit beta) (RNA polymerase subunit beta); DNA-directed RNA polymerase subunit beta' (transcriptase subunit beta') (RNA polymerase subunit beta'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' 1181855 rpoBC 8208986 rpoBC Helicobacter pylori B38 DNA-directed RNA polymerase subunit beta/beta' YP_003057851.1 1173183 R 592205 CDS YP_003057852.1 254779746 8208971 complement(1182078..1182455) 1 NC_012973.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1182455 rplL 8208971 rplL Helicobacter pylori B38 50S ribosomal protein L7/L12 YP_003057852.1 1182078 R 592205 CDS YP_003057853.1 254779747 8208948 complement(1182501..1182995) 1 NC_012973.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1182995 rplJ 8208948 rplJ Helicobacter pylori B38 50S ribosomal protein L10 YP_003057853.1 1182501 R 592205 CDS YP_003057854.1 254779748 8208946 complement(1183104..1183808) 1 NC_012973.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1183808 rplA 8208946 rplA Helicobacter pylori B38 50S ribosomal protein L1 YP_003057854.1 1183104 R 592205 CDS YP_003057855.1 254779749 8208939 complement(1183853..1184278) 1 NC_012973.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1184278 rplK 8208939 rplK Helicobacter pylori B38 50S ribosomal protein L11 YP_003057855.1 1183853 R 592205 CDS YP_003057856.1 254779750 8208947 complement(1184296..1184826) 1 NC_012973.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1184826 nusG 8208947 nusG Helicobacter pylori B38 transcription antitermination protein NusG YP_003057856.1 1184296 R 592205 CDS YP_003057857.1 254779751 8208825 complement(1184853..1185032) 1 NC_012973.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1185032 secE 8208825 secE Helicobacter pylori B38 preprotein translocase subunit SecE YP_003057857.1 1184853 R 592205 CDS YP_003057858.1 254779752 8208332 complement(1185289..1185447) 1 NC_012973.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1185447 rpmG 8208332 rpmG Helicobacter pylori B38 50S ribosomal protein L33 YP_003057858.1 1185289 R 592205 CDS YP_003057859.1 254779753 8208966 complement(1185481..1186680) 1 NC_012973.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1186680 tuf 8208966 tuf Helicobacter pylori B38 elongation factor Tu YP_003057859.1 1185481 R 592205 CDS YP_003057860.1 254779754 8208328 1187381..1189117 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter ATP-binding protein and permease; membrane protein 1189117 8208328 HELPY_1180 Helicobacter pylori B38 ABC transporter ATP-binding protein and permease; membrane protein YP_003057860.1 1187381 D 592205 CDS YP_003057861.1 254779755 8208117 complement(1189128..1189796) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8702766; Product type e : enzyme; haloacid dehalogenase 1189796 8208117 HELPY_1181 Helicobacter pylori B38 haloacid dehalogenase YP_003057861.1 1189128 R 592205 CDS YP_003057862.1 254779756 8208118 complement(1189997..1190986) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 2277628, 7607512, 7663118, 20576144, 98012982, 21126955; Product type e : enzyme; type II adenosine specific DNA methyltransferase M.HpyAI 1190986 hpyAIM 8208118 hpyAIM Helicobacter pylori B38 type II adenosine specific DNA methyltransferase M.HpyAI YP_003057862.1 1189997 R 592205 CDS YP_003057863.1 254779757 8208121 complement(1191751..1192266) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10672045, 11395450, 16481326, 15516574, 10930739; Product type e : enzyme; Serine acetyltransferase (SAT) 1192266 cysE 8208121 cysE Helicobacter pylori B38 Serine acetyltransferase (SAT) YP_003057863.1 1191751 R 592205 CDS YP_003057864.1 254779758 8208326 complement(1192864..1193181) 1 NC_012973.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1193181 atpE 8208326 atpE Helicobacter pylori B38 F0F1 ATP synthase subunit C YP_003057864.1 1192864 R 592205 CDS YP_003057865.1 254779759 8208397 complement(1193314..1195380) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8825779, 16428774, 16299002, 16282984, 16275923, 16237005; Product type e : enzyme; polynucleotide phosphorylase/polyadenylase 1195380 pnp 8208397 pnp Helicobacter pylori B38 polynucleotide phosphorylase/polyadenylase YP_003057865.1 1193314 R 592205 CDS YP_003057866.1 254779760 8208861 complement(1195383..1196087) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphoribosyltransferase 1196087 8208861 HELPY_1190 Helicobacter pylori B38 phosphoribosyltransferase YP_003057866.1 1195383 R 592205 CDS YP_003057867.1 254779761 8208122 complement(1196101..1198362) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 95110156, 12207697; Product type m : membrane component; organic solvent tolerance protein 1198362 imp 8208122 imp Helicobacter pylori B38 organic solvent tolerance protein YP_003057867.1 1196101 R 592205 CDS YP_003057868.1 254779762 8208711 complement(1198365..1198844) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1198844 8208711 HELPY_1193 Helicobacter pylori B38 hypothetical protein YP_003057868.1 1198365 R 592205 CDS YP_003057869.1 254779763 8208123 complement(1198893..1200167) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 98047359, 15271960, 9683487; Product type e : enzyme; phosphoribosylamine--glycine ligase 1200167 purD 8208123 purD Helicobacter pylori B38 phosphoribosylamine--glycine ligase YP_003057869.1 1198893 R 592205 CDS YP_003057870.1 254779764 8208887 complement(1200480..1201166) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 98254124, 99449617, 16399363, 16400872; Product type t : transporter; ABC transporter ATP-binding protein 1201166 8208887 HELPY_1195 Helicobacter pylori B38 ABC transporter ATP-binding protein YP_003057870.1 1200480 R 592205 CDS YP_003057871.1 254779765 8208124 complement(1201160..1201864) 1 NC_012973.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 1201864 uppS 8208124 uppS Helicobacter pylori B38 UDP pyrophosphate synthase YP_003057871.1 1201160 R 592205 CDS YP_003057872.1 254779766 8209074 complement(1201904..1204744) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; D-lactate dehydrogenase 1204744 8209074 HELPY_1197 Helicobacter pylori B38 D-lactate dehydrogenase YP_003057872.1 1201904 R 592205 CDS YP_003057873.1 254779767 8208125 1204816..1205148 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1205148 8208125 HELPY_1198 Helicobacter pylori B38 hypothetical protein YP_003057873.1 1204816 D 592205 CDS YP_003057874.1 254779768 8208126 1205151..1205831 1 NC_012973.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1205831 hemD 8208126 hemD Helicobacter pylori B38 uroporphyrinogen-III synthase YP_003057874.1 1205151 D 592205 CDS YP_003057875.1 254779769 8208627 1205879..1206271 1 NC_012973.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1206271 crcB 8208627 crcB Helicobacter pylori B38 camphor resistance protein CrcB YP_003057875.1 1205879 D 592205 CDS YP_003057876.1 254779770 8208442 complement(1206317..1207354) 1 NC_012973.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1207354 hemN 8208442 hemN Helicobacter pylori B38 coproporphyrinogen III oxidase YP_003057876.1 1206317 R 592205 CDS YP_003057877.1 254779771 8208633 1207450..1207740 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; cytochrome c553 1207740 8208633 HELPY_1202 Helicobacter pylori B38 cytochrome c553 YP_003057877.1 1207450 D 592205 CDS YP_003057878.1 254779772 8208127 1207901..1208368 1 NC_012973.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1208368 8208127 HELPY_1203 Helicobacter pylori B38 dinucleoside polyphosphate hydrolase YP_003057878.1 1207901 D 592205 CDS YP_003057879.1 254779773 8208128 1208370..1209587 1 NC_012973.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1209587 lysC 8208128 lysC Helicobacter pylori B38 aspartate kinase YP_003057879.1 1208370 D 592205 CDS YP_003057880.1 254779774 8208746 1209584..1210126 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17645450, 17683397; Product type f : factor; DnaA initiator-associating factor for replication initiation HobA 1210126 hobA 8208746 hobA Helicobacter pylori B38 DnaA initiator-associating factor for replication initiation HobA YP_003057880.1 1209584 D 592205 CDS YP_003057881.1 254779775 8208635 1210123..1210779 1 NC_012973.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1210779 holB 8208635 holB Helicobacter pylori B38 DNA polymerase III subunit delta' YP_003057881.1 1210123 D 592205 CDS YP_003057882.1 254779776 8208644 1210776..1211918 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15554970, 16553853, 16503987, 15554970, 10817704, 10471557, 8586264; Product type e : enzyme; Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase) 1211918 folP 8208644 folP Helicobacter pylori B38 Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase) YP_003057882.1 1210776 D 592205 CDS YP_003057883.1 254779777 8208553 complement(1212007..1212468) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1212468 8208553 HELPY_1208 Helicobacter pylori B38 hypothetical protein YP_003057883.1 1212007 R 592205 CDS YP_003057884.1 254779778 8208129 1212859..1213755 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1213755 8208129 HELPY_1209 Helicobacter pylori B38 hypothetical protein YP_003057884.1 1212859 D 592205 CDS YP_003057885.1 254779779 8208130 1213759..1215006 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 1215006 8208130 HELPY_1210 Helicobacter pylori B38 hypothetical protein YP_003057885.1 1213759 D 592205 CDS YP_003057886.1 254779780 8208131 1215085..1215636 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1215636 8208131 HELPY_1211 Helicobacter pylori B38 hypothetical protein YP_003057886.1 1215085 D 592205 CDS YP_003057887.1 254779781 8208132 1215636..1216763 1 NC_012973.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1216763 carA 8208132 carA Helicobacter pylori B38 carbamoyl phosphate synthase small subunit YP_003057887.1 1215636 D 592205 CDS YP_003057888.1 254779782 8208413 1216929..1217933 1 NC_012973.1 formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 1217933 amiF 8208413 amiF Helicobacter pylori B38 formamidase YP_003057888.1 1216929 D 592205 CDS YP_003057889.1 254779783 8208376 complement(1218145..1218264) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1218264 8208376 HELPY_1214 Helicobacter pylori B38 hypothetical protein YP_003057889.1 1218145 R 592205 CDS YP_003057890.1 254779784 8208133 complement(1218378..1218950) 1 NC_012973.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1218950 8208133 HELPY_1215 Helicobacter pylori B38 Maf-like protein YP_003057890.1 1218378 R 592205 CDS YP_003057891.1 254779785 8208134 complement(1218952..1221495) 1 NC_012973.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1221495 alaS 8208134 alaS Helicobacter pylori B38 alanyl-tRNA synthetase YP_003057891.1 1218952 R 592205 CDS YP_003057892.1 254779786 8208371 1221614..1221844 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1221844 8208371 HELPY_1217 Helicobacter pylori B38 hypothetical protein YP_003057892.1 1221614 D 592205 CDS YP_003057893.1 254779787 8208137 complement(1225450..1225707) 1 NC_012973.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1225707 rpsR 8208137 rpsR Helicobacter pylori B38 30S ribosomal protein S18 YP_003057893.1 1225450 R 592205 CDS YP_003057894.1 254779788 8208992 complement(1225730..1226275) 1 NC_012973.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1226275 ssb 8208992 ssb Helicobacter pylori B38 single-stranded DNA-binding protein YP_003057894.1 1225730 R 592205 CDS YP_003057895.1 254779789 8209020 complement(1226285..1226713) 1 NC_012973.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1226713 rpsF 8209020 rpsF Helicobacter pylori B38 30S ribosomal protein S6 YP_003057895.1 1226285 R 592205 CDS YP_003057896.1 254779790 8208980 complement(1227058..1228080) 1 NC_012973.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1228080 holA 8208980 holA Helicobacter pylori B38 DNA polymerase III subunit delta YP_003057896.1 1227058 R 592205 CDS YP_003057897.1 254779791 8208643 complement(1228070..1230007) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16563345, 15664199, 11948193, 9603904, 1400189; Product type e : enzyme; ribonuclease R 1230007 rnr 8208643 rnr Helicobacter pylori B38 ribonuclease R YP_003057897.1 1228070 R 592205 CDS YP_003057898.1 254779792 8208933 complement(1230007..1230798) 1 NC_012973.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1230798 aroE 8208933 aroE Helicobacter pylori B38 shikimate 5-dehydrogenase YP_003057898.1 1230007 R 592205 CDS YP_003057899.1 254779793 8208383 complement(1230806..1231396) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1231396 8208383 HELPY_1226 Helicobacter pylori B38 hypothetical protein YP_003057899.1 1230806 R 592205 CDS YP_003057900.1 254779794 8208138 complement(1231405..1232451) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter permease 1232451 8208138 HELPY_1227 Helicobacter pylori B38 ABC transporter permease YP_003057900.1 1231405 R 592205 CDS YP_003057901.1 254779795 8208139 complement(1232448..1234229) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter substrate-binding protein 1234229 8208139 HELPY_1228 Helicobacter pylori B38 ABC transporter substrate-binding protein YP_003057901.1 1232448 R 592205 CDS YP_003057902.1 254779796 8208140 complement(1234230..1235210) 1 NC_012973.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1235210 trpS 8208140 trpS Helicobacter pylori B38 tryptophanyl-tRNA synthetase YP_003057902.1 1234230 R 592205 CDS YP_003057903.1 254779797 8209057 complement(1235281..1236018) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; biotin biosynthesis protein BioC 1236018 bioC 8209057 bioC Helicobacter pylori B38 biotin biosynthesis protein BioC YP_003057903.1 1235281 R 592205 CDS YP_003057904.1 254779798 8208406 1236135..1236740 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15039361, 14659543, 9184221, 16677301, 16428426, 16154141, 15546659; Product type t : transporter; preprotein translocase subunit SecG 1236740 secG 8208406 secG Helicobacter pylori B38 preprotein translocase subunit SecG YP_003057904.1 1236135 D 592205 CDS YP_003057905.1 254779799 8209007 1236740..1237297 1 NC_012973.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1237297 frr 8209007 frr Helicobacter pylori B38 ribosome recycling factor YP_003057905.1 1236740 D 592205 CDS YP_003057906.1 254779800 8208560 1237301..1237906 1 NC_012973.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1237906 pyrE 8208560 pyrE Helicobacter pylori B38 orotate phosphoribosyltransferase YP_003057906.1 1237301 D 592205 CDS YP_003057907.1 254779801 8208895 1237896..1238360 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1238360 8208895 HELPY_1234 Helicobacter pylori B38 hypothetical protein YP_003057907.1 1237896 D 592205 CDS YP_003057908.1 254779802 8208141 1238357..1239046 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7498786, 10381378; Product type pe : enzyme; NAD+-dependent deacetylase, Sir2 family 1239046 8208141 HELPY_1235 Helicobacter pylori B38 NAD+-dependent deacetylase, Sir2 family YP_003057908.1 1238357 D 592205 CDS YP_003057909.1 254779803 8208142 1239154..1239555 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A 1239555 nuoA 8208142 nuoA Helicobacter pylori B38 NADH dehydrogenase subunit A YP_003057909.1 1239154 D 592205 CDS YP_003057910.1 254779804 8208809 1239555..1240034 1 NC_012973.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1240034 nuoB 8208809 nuoB Helicobacter pylori B38 NADH dehydrogenase subunit B YP_003057910.1 1239555 D 592205 CDS YP_003057911.1 254779805 8208810 1240034..1240831 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C 1240831 nuoC 8208810 nuoC Helicobacter pylori B38 NADH dehydrogenase subunit C YP_003057911.1 1240034 D 592205 CDS YP_003057912.1 254779806 8208811 1240833..1242062 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1242062 nuoD 8208811 nuoD Helicobacter pylori B38 NADH dehydrogenase subunit D YP_003057912.1 1240833 D 592205 CDS YP_003057913.1 254779807 8208812 1242059..1242289 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15922336; Product type e : enzyme; NADH-ubiquinone oxidoreductase subunit E 1242289 nuoE 8208812 nuoE Helicobacter pylori B38 NADH-ubiquinone oxidoreductase subunit E YP_003057913.1 1242059 D 592205 CDS YP_003057914.1 254779808 8208813 1242292..1243278 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15922336, 15922336; Product type e : enzyme; NADH-ubiquinone oxidoreductase subunit F 1243278 nuoF 8208813 nuoF Helicobacter pylori B38 NADH-ubiquinone oxidoreductase subunit F YP_003057914.1 1242292 D 592205 CDS YP_003057915.1 254779809 8208814 1243275..1245836 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1245836 nuoG 8208814 nuoG Helicobacter pylori B38 NADH dehydrogenase subunit G YP_003057915.1 1243275 D 592205 CDS YP_003057916.1 254779810 8208815 1245833..1246822 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1246822 nuoH 8208815 nuoH Helicobacter pylori B38 NADH dehydrogenase subunit H YP_003057916.1 1245833 D 592205 CDS YP_003057917.1 254779811 8208816 1246833..1247495 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1247495 nuoI 8208816 nuoI Helicobacter pylori B38 NADH dehydrogenase subunit I YP_003057917.1 1246833 D 592205 CDS YP_003057918.1 254779812 8208817 1247488..1248036 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1248036 nuoJ 8208817 nuoJ Helicobacter pylori B38 NADH dehydrogenase subunit J YP_003057918.1 1247488 D 592205 CDS YP_003057919.1 254779813 8208818 1248033..1248335 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1248335 nuoK 8208818 nuoK Helicobacter pylori B38 NADH dehydrogenase subunit K YP_003057919.1 1248033 D 592205 CDS YP_003057920.1 254779814 8208819 1248338..1250176 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1250176 nuoL 8208819 nuoL Helicobacter pylori B38 NADH dehydrogenase subunit L YP_003057920.1 1248338 D 592205 CDS YP_003057921.1 254779815 8208820 1250180..1251718 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1251718 nuoM 8208820 nuoM Helicobacter pylori B38 NADH dehydrogenase subunit M YP_003057921.1 1250180 D 592205 CDS YP_003057922.1 254779816 8208821 1251705..1253177 1 NC_012973.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1253177 nuoN 8208821 nuoN Helicobacter pylori B38 NADH dehydrogenase subunit N YP_003057922.1 1251705 D 592205 CDS YP_003057923.1 254779817 8208822 1253167..1255572 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7715450; Product type pf : factor; paralysed flagella protein PflA 1255572 8208822 HELPY_1250 Helicobacter pylori B38 paralysed flagella protein PflA YP_003057923.1 1253167 D 592205 CDS YP_003057924.1 254779818 8208143 1255574..1256950 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1712067; Product type pe : enzyme; phosphomannomutase (PMM) 1256950 8208143 HELPY_1252 Helicobacter pylori B38 phosphomannomutase (PMM) YP_003057924.1 1255574 D 592205 CDS YP_003057925.1 254779819 8208144 1257243..1257530 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1257530 8208144 HELPY_1253 Helicobacter pylori B38 hypothetical protein YP_003057925.1 1257243 D 592205 CDS YP_003057926.1 254779820 8208145 complement(1257772..1258560) 1 NC_012973.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1258560 trpA 8208145 trpA Helicobacter pylori B38 tryptophan synthase subunit alpha YP_003057926.1 1257772 R 592205 CDS YP_003057927.1 254779821 8209051 complement(1258557..1259738) 1 NC_012973.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1259738 trpB 8209051 trpB Helicobacter pylori B38 tryptophan synthase subunit beta YP_003057927.1 1258557 R 592205 CDS YP_003057928.1 254779822 8209052 complement(1259739..1261097) 1 NC_012973.1 [Indole-3-glycerol phosphate synthase, N-terminal (IGPS); N-(5-phosphoribosyl)anthranilate isomerase, C-terminal (PRAI)]; monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1261097 trpCF 8209052 trpCF Helicobacter pylori B38 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_003057928.1 1259739 R 592205 CDS YP_003057929.1 254779823 8209053 complement(1261090..1262097) 1 NC_012973.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1262097 trpD 8209053 trpD Helicobacter pylori B38 anthranilate phosphoribosyltransferase YP_003057929.1 1261090 R 592205 CDS YP_003057930.1 254779824 8209054 complement(1262094..1262678) 1 NC_012973.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1262678 trpG 8209054 trpG Helicobacter pylori B38 anthranilate synthase component II YP_003057930.1 1262094 R 592205 CDS YP_003057931.1 254779825 8209056 complement(1262675..1264177) 1 NC_012973.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1264177 trpE 8209056 trpE Helicobacter pylori B38 anthranilate synthase component I YP_003057931.1 1262675 R 592205 CDS YP_003057932.1 254779826 8209055 complement(1264411..1265466) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyltransferase 1265466 8209055 HELPY_1260 Helicobacter pylori B38 glycosyltransferase YP_003057932.1 1264411 R 592205 CDS YP_003057933.1 254779827 8208146 complement(1265534..1266271) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11395461, 10760156; Product type pm : membrane component; acid phosphatase lipoprotein 1266271 8208146 HELPY_1261 Helicobacter pylori B38 acid phosphatase lipoprotein YP_003057933.1 1265534 R 592205 CDS YP_003057934.1 254779828 8208147 1266395..1266943 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1266943 8208147 HELPY_1262 Helicobacter pylori B38 hypothetical protein YP_003057934.1 1266395 D 592205 CDS YP_003057935.1 254779829 8208148 complement(1267007..1267660) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8662211, 1898926; Product type r : regulator; transcriptional regulator 1267660 8208148 HELPY_1263 Helicobacter pylori B38 transcriptional regulator YP_003057935.1 1267007 R 592205 CDS YP_003057936.1 254779830 8208149 1268352..1268711 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16699190, 15795230, 7929447; Product type e : enzyme; Pantothenate kinase (type III) 1268711 coaX 8208149 coaX Helicobacter pylori B38 Pantothenate kinase (type III) YP_003057936.1 1268352 D 592205 CDS YP_003057937.1 254779831 8208431 1268751..1269245 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; Product type pm : membrane component; hypothetical protein 1269245 8208431 HELPY_1265 Helicobacter pylori B38 hypothetical protein YP_003057937.1 1268751 D 592205 CDS YP_003057938.1 254779832 8208322 1269431..1270093 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15968063, 2546921, 2198247, 1991724; Product type pt : transporter; nicotinamide mononucleotide transporter PnuC 1270093 8208322 HELPY_1266 Helicobacter pylori B38 nicotinamide mononucleotide transporter PnuC YP_003057938.1 1269431 D 592205 CDS YP_003057939.1 254779833 8208151 1270090..1270695 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16728979, 15150256, 11435118; Product type pe : enzyme; thiamine pyrophosphokinase 1270695 8208151 HELPY_1267 Helicobacter pylori B38 thiamine pyrophosphokinase YP_003057939.1 1270090 D 592205 CDS YP_003057940.1 254779834 8208152 complement(1271340..1271690) 1 NC_012973.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1271690 rplQ 8208152 rplQ Helicobacter pylori B38 50S ribosomal protein L17 YP_003057940.1 1271340 R 592205 CDS YP_003057941.1 254779835 8208953 complement(1271690..1272724) 1 NC_012973.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1272724 rpoA 8208953 rpoA Helicobacter pylori B38 DNA-directed RNA polymerase subunit alpha YP_003057941.1 1271690 R 592205 CDS YP_003057942.1 254779836 8208970 complement(1272736..1273362) 1 NC_012973.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1273362 rpsD 8208970 rpsD Helicobacter pylori B38 30S ribosomal protein S4 YP_003057942.1 1272736 R 592205 CDS YP_003057943.1 254779837 8208978 complement(1273372..1273767) 1 NC_012973.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1273767 rpsK 8208978 rpsK Helicobacter pylori B38 30S ribosomal protein S11 YP_003057943.1 1273372 R 592205 CDS YP_003057944.1 254779838 8208985 complement(1273790..1274152) 1 NC_012973.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1274152 rpsM 8208985 rpsM Helicobacter pylori B38 30S ribosomal protein S13 YP_003057944.1 1273790 R 592205 CDS YP_003057945.1 254779839 8208987 complement(1274156..1274269) 1 NC_012973.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1274269 rpmJ 8208987 rpmJ Helicobacter pylori B38 50S ribosomal protein L36 YP_003057945.1 1274156 R 592205 CDS YP_003057946.1 254779840 8208968 complement(1274347..1274565) 1 NC_012973.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1274565 infA 8208968 infA Helicobacter pylori B38 translation initiation factor IF-1 YP_003057946.1 1274347 R 592205 CDS YP_003057947.1 254779841 8208712 complement(1274565..1275326) 1 NC_012973.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1275326 map 8208712 map Helicobacter pylori B38 methionine aminopeptidase YP_003057947.1 1274565 R 592205 CDS YP_003057948.1 254779842 8208750 complement(1275326..1276588) 1 NC_012973.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1276588 secY 8208750 secY Helicobacter pylori B38 preprotein translocase subunit SecY YP_003057948.1 1275326 R 592205 CDS YP_003057949.1 254779843 8209008 complement(1276628..1277029) 1 NC_012973.1 late assembly protein; 50S ribosomal protein L15 1277029 rplO 8209008 rplO Helicobacter pylori B38 50S ribosomal protein L15 YP_003057949.1 1276628 R 592205 CDS YP_003057950.1 254779844 8208951 complement(1277049..1277510) 1 NC_012973.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1277510 rpsE 8208951 rpsE Helicobacter pylori B38 30S ribosomal protein S5 YP_003057950.1 1277049 R 592205 CDS YP_003057951.1 254779845 8208979 complement(1277507..1277866) 1 NC_012973.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1277866 rplR 8208979 rplR Helicobacter pylori B38 50S ribosomal protein L18 YP_003057951.1 1277507 R 592205 CDS YP_003057952.1 254779846 8208954 complement(1277877..1278413) 1 NC_012973.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1278413 rplF 8208954 rplF Helicobacter pylori B38 50S ribosomal protein L6 YP_003057952.1 1277877 R 592205 CDS YP_003057953.1 254779847 8208944 complement(1278424..1278819) 1 NC_012973.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1278819 rpsH 8208944 rpsH Helicobacter pylori B38 30S ribosomal protein S8 YP_003057953.1 1278424 R 592205 CDS YP_003057954.1 254779848 8208982 complement(1278829..1279014) 1 NC_012973.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 1279014 rpsN 8208982 rpsN Helicobacter pylori B38 30S ribosomal protein S14 YP_003057954.1 1278829 R 592205 CDS YP_003057955.1 254779849 8208988 complement(1279024..1279569) 1 NC_012973.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1279569 rplE 8208988 rplE Helicobacter pylori B38 50S ribosomal protein L5 YP_003057955.1 1279024 R 592205 CDS YP_003057956.1 254779850 8208943 complement(1279582..1279803) 1 NC_012973.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1279803 rplX 8208943 rplX Helicobacter pylori B38 50S ribosomal protein L24 YP_003057956.1 1279582 R 592205 CDS YP_003057957.1 254779851 8208960 complement(1279803..1280171) 1 NC_012973.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1280171 rplN 8208960 rplN Helicobacter pylori B38 50S ribosomal protein L14 YP_003057957.1 1279803 R 592205 CDS YP_003057958.1 254779852 8208950 complement(1280174..1280434) 1 NC_012973.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1280434 rpsQ 8208950 rpsQ Helicobacter pylori B38 30S ribosomal protein S17 YP_003057958.1 1280174 R 592205 CDS YP_003057959.1 254779853 8208991 complement(1280448..1280660) 1 NC_012973.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1280660 rpmC 8208991 rpmC Helicobacter pylori B38 50S ribosomal protein L29 YP_003057959.1 1280448 R 592205 CDS YP_003057960.1 254779854 8208963 complement(1280635..1281060) 1 NC_012973.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1281060 rplP 8208963 rplP Helicobacter pylori B38 50S ribosomal protein L16 YP_003057960.1 1280635 R 592205 CDS YP_003057961.1 254779855 8208952 complement(1281063..1281767) 1 NC_012973.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1281767 rpsC 8208952 rpsC Helicobacter pylori B38 30S ribosomal protein S3 YP_003057961.1 1281063 R 592205 CDS YP_003057962.1 254779856 8208977 complement(1281771..1282139) 1 NC_012973.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1282139 rplV 8208977 rplV Helicobacter pylori B38 50S ribosomal protein L22 YP_003057962.1 1281771 R 592205 CDS YP_003057963.1 254779857 8208958 complement(1282149..1282430) 1 NC_012973.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1282430 rpsS 8208958 rpsS Helicobacter pylori B38 30S ribosomal protein S19 YP_003057963.1 1282149 R 592205 CDS YP_003057964.1 254779858 8208993 complement(1282442..1283272) 1 NC_012973.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1283272 rplB 8208993 rplB Helicobacter pylori B38 50S ribosomal protein L2 YP_003057964.1 1282442 R 592205 CDS YP_003057965.1 254779859 8208940 complement(1283288..1283569) 1 NC_012973.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1283569 rplW 8208940 rplW Helicobacter pylori B38 50S ribosomal protein L23 YP_003057965.1 1283288 R 592205 CDS YP_003057966.1 254779860 8208959 complement(1283573..1284220) 1 NC_012973.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1284220 rplD 8208959 rplD Helicobacter pylori B38 50S ribosomal protein L4 YP_003057966.1 1283573 R 592205 CDS YP_003057967.1 254779861 8208942 complement(1284255..1284830) 1 NC_012973.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1284830 rplC 8208942 rplC Helicobacter pylori B38 50S ribosomal protein L3 YP_003057967.1 1284255 R 592205 CDS YP_003057968.1 254779862 8208941 complement(1284867..1285181) 1 NC_012973.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1285181 rpsJ 8208941 rpsJ Helicobacter pylori B38 30S ribosomal protein S10 YP_003057968.1 1284867 R 592205 CDS YP_003057969.1 254779863 8208984 1285344..1286477 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 1286477 8208984 HELPY_1297 Helicobacter pylori B38 hypothetical protein YP_003057969.1 1285344 D 592205 CDS YP_003057970.1 254779864 8208153 1286743..1287321 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1287321 8208153 HELPY_1298 Helicobacter pylori B38 hypothetical protein YP_003057970.1 1286743 D 592205 CDS YP_003057971.1 254779865 8208154 complement(1287295..1287909) 1 NC_012973.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1287909 rnhB 8208154 rnhB Helicobacter pylori B38 ribonuclease HII YP_003057971.1 1287295 R 592205 CDS YP_003057972.1 254779866 8208930 complement(1287940..1288191) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1288191 8208930 HELPY_1300 Helicobacter pylori B38 hypothetical protein YP_003057972.1 1287940 R 592205 CDS YP_003057973.1 254779867 8208155 complement(1288214..1289605) 1 NC_012973.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1289605 fumC 8208155 fumC Helicobacter pylori B38 fumarate hydratase YP_003057973.1 1288214 R 592205 CDS YP_003057974.1 254779868 8208568 1289780..1290157 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1290157 8208568 HELPY_1302 Helicobacter pylori B38 hypothetical protein YP_003057974.1 1289780 D 592205 CDS YP_003057975.1 254779869 8208156 1290162..1291400 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 1291400 8208156 HELPY_1303 Helicobacter pylori B38 hypothetical protein YP_003057975.1 1290162 D 592205 CDS YP_003057976.1 254779870 8208157 1291397..1292422 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12877469, 11023484, 12877469, 10473554; Product type pt : transporter; cobalt-zinc-cadmium resistance protein CzcB 1292422 8208157 HELPY_1304 Helicobacter pylori B38 cobalt-zinc-cadmium resistance protein CzcB YP_003057976.1 1291397 D 592205 CDS YP_003057977.1 254779871 8208158 1292423..1295530 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12877469, 11023484, 12877469, 10473554; Product type pt : transporter; heavy metal efflux pump CzcA 1295530 8208158 HELPY_1305 Helicobacter pylori B38 heavy metal efflux pump CzcA YP_003057977.1 1292423 D 592205 CDS YP_003057978.1 254779872 8208159 complement(1295511..1295867) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9287000, 11162545; Product type pt : transporter; branched-chain amino acid transport protein AzlD; membrane protein 1295867 8208159 HELPY_1306 Helicobacter pylori B38 branched-chain amino acid transport protein AzlD; membrane protein YP_003057978.1 1295511 R 592205 CDS YP_003057979.1 254779873 8208160 complement(1295861..1296547) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9287000, 11162545; Product type pt : transporter; branched-chain amino acid transport protein AzlC; membrane protein 1296547 8208160 HELPY_1307 Helicobacter pylori B38 branched-chain amino acid transport protein AzlC; membrane protein YP_003057979.1 1295861 R 592205 CDS YP_003057980.1 254779874 8208161 complement(1296558..1297667) 1 NC_012973.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1297667 dnaJ2 8208161 dnaJ2 Helicobacter pylori B38 chaperone protein DnaJ YP_003057980.1 1296558 R 592205 CDS YP_003057981.1 254779875 8208467 1297792..1298934 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1298934 8208467 HELPY_1309 Helicobacter pylori B38 hypothetical protein YP_003057981.1 1297792 D 592205 CDS YP_003057982.1 254779876 8208162 complement(1298978..1300006) 1 NC_012973.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1300006 mnmA 8208162 mnmA Helicobacter pylori B38 tRNA-specific 2-thiouridylase MnmA YP_003057982.1 1298978 R 592205 CDS YP_003057983.1 254779877 8209050 1300146..1300907 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1300907 8209050 HELPY_1311 Helicobacter pylori B38 hypothetical protein YP_003057983.1 1300146 D 592205 CDS YP_003057984.1 254779878 8208163 complement(1300904..1301419) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10894752, 11704676; Product type pe : enzyme; nicotinate-nucleotide adenyltransferase 1301419 8208163 HELPY_1312 Helicobacter pylori B38 nicotinate-nucleotide adenyltransferase YP_003057984.1 1300904 R 592205 CDS YP_003057985.1 254779879 8208164 complement(1301412..1301858) 1 NC_012973.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 1301858 nikR 8208164 nikR Helicobacter pylori B38 nickel responsive regulator YP_003057985.1 1301412 R 592205 CDS YP_003057986.1 254779880 8208802 1302192..1302629 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12890020, 16321934, 15819630, 2670903, 9643536, 981166, 7642501, 9159515; Product type t : transporter; Biopolymer transport accessory protein; membrane protein 1302629 exbB2 8208802 exbB2 Helicobacter pylori B38 Biopolymer transport accessory protein; membrane protein YP_003057986.1 1302192 D 592205 CDS YP_003057987.1 254779881 8208488 1302626..1303015 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12890020, 16321934, 15819630, 9643536, 9811664, 9371459, 7642501; Product type t : transporter; Biopolymer transport protein ExbD 1303015 exbD2 8208488 exbD2 Helicobacter pylori B38 Biopolymer transport protein ExbD YP_003057987.1 1302626 D 592205 CDS YP_003057988.1 254779882 8208491 1302981..1303832 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10931324; Product type t : transporter; Siderophore-mediated iron transport protein 1303832 tonB2 8208491 tonB2 Helicobacter pylori B38 Siderophore-mediated iron transport protein YP_003057988.1 1302981 D 592205 CDS YP_003057989.1 254779883 8209045 1304027..1306117 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopM 1306117 hopM 8209045 hopM Helicobacter pylori B38 outer membrane protein HopM YP_003057989.1 1304027 D 592205 CDS YP_003057990.1 254779884 8208662 complement(1306256..1306984) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11016400, 10069007; Product type pt : transporter; transporter; membrane protein 1306984 8208662 HELPY_1318 Helicobacter pylori B38 transporter; membrane protein YP_003057990.1 1306256 R 592205 CDS YP_003057991.1 254779885 8208165 complement(1306991..1307947) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12065537, 16857941, 16720382, 16598263, 16179994, 15516579, 15231793; Product type t : transporter; Magnesium, nickel and cobalt transport protein CorA 1307947 corA 8208165 corA Helicobacter pylori B38 Magnesium, nickel and cobalt transport protein CorA YP_003057991.1 1306991 R 592205 CDS YP_003057992.1 254779886 8208440 complement(1307963..1309171) 1 NC_012973.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1309171 pgk 8208440 pgk Helicobacter pylori B38 phosphoglycerate kinase YP_003057992.1 1307963 R 592205 CDS YP_003057993.1 254779887 8208854 complement(1309187..1310179) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15250823, 16527864; Product type pe : enzyme; glyceraldehyde-3-phosphate dehydrogenase 1310179 8208854 HELPY_1322 Helicobacter pylori B38 glyceraldehyde-3-phosphate dehydrogenase YP_003057993.1 1309187 R 592205 CDS YP_003057994.1 254779888 8208166 complement(1310261..1310962) 1 NC_012973.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1310962 ung 8208166 ung Helicobacter pylori B38 uracil-DNA glycosylase YP_003057994.1 1310261 R 592205 CDS YP_003057995.1 254779889 8209073 complement(1310959..1311660) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16151217, 10361297, 8748025; Product type pe : enzyme; 1-acylglycerol-3-phosphate O-acyltransferase 1311660 8209073 HELPY_1324 Helicobacter pylori B38 1-acylglycerol-3-phosphate O-acyltransferase YP_003057995.1 1310959 R 592205 CDS YP_003057996.1 254779890 8208167 complement(1311647..1312762) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1312762 8208167 HELPY_1325 Helicobacter pylori B38 hypothetical protein YP_003057996.1 1311647 R 592205 CDS YP_003057997.1 254779891 8208168 complement(1312825..1314204) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7845208, 10966643, 9141685, 8576225, 7499412, 1856173; Product type e : enzyme; Carboxyl-terminal protease, S41A family 1314204 8208168 HELPY_1326 Helicobacter pylori B38 Carboxyl-terminal protease, S41A family YP_003057997.1 1312825 R 592205 CDS YP_003057998.1 254779892 8208173 1316041..1316298 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1316298 8208173 HELPY_1331 Helicobacter pylori B38 hypothetical protein YP_003057998.1 1316041 D 592205 CDS YP_003057999.1 254779893 8208174 1316300..1316485 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1316485 8208174 HELPY_1332 Helicobacter pylori B38 hypothetical protein YP_003057999.1 1316300 D 592205 CDS YP_003058000.1 254779894 8208175 1316482..1317114 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 1317114 8208175 HELPY_1333 Helicobacter pylori B38 Serine recombinase-transposase, OrfA, ISHp609 YP_003058000.1 1316482 D 592205 CDS YP_003058001.1 254779895 8208176 1317101..1318330 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 1318330 8208176 HELPY_1334 Helicobacter pylori B38 transposase, OrfB, ISHp609 YP_003058001.1 1317101 D 592205 CDS YP_003058002.1 254779896 8208179 1319610..1321046 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphorylase 1321046 8208179 HELPY_1338 Helicobacter pylori B38 phosphorylase YP_003058002.1 1319610 D 592205 CDS YP_003058003.1 254779897 8208181 complement(1321452..1322324) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12034832, 11703661, 11166995, 11133936, 11226310; Product type e : enzyme; type II restriction endonuclease 1322324 hypAIVR 8208181 hypAIVR Helicobacter pylori B38 type II restriction endonuclease YP_003058003.1 1321452 R 592205 CDS YP_003058004.1 254779898 8208700 complement(1322324..1323403) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12034832, 11703661, 11166995, 11133936, 11226310; Product type e : enzyme; type II m6A methylase 1323403 hpyAIVM 8208700 hpyAIVM Helicobacter pylori B38 type II m6A methylase YP_003058004.1 1322324 R 592205 CDS YP_003058005.1 254779899 8208184 complement(1327167..1327988) 1 NC_012973.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1327988 nadC 8208184 nadC Helicobacter pylori B38 nicotinate-nucleotide pyrophosphorylase YP_003058005.1 1327167 R 592205 CDS YP_003058006.1 254779900 8208794 complement(1327988..1328998) 1 NC_012973.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1328998 nadA 8208794 nadA Helicobacter pylori B38 quinolinate synthetase YP_003058006.1 1327988 R 592205 CDS YP_003058007.1 254779901 8208793 complement(1328988..1329791) 1 NC_012973.1 [Contains: phosphatidylserine decarboxylase alpha chain; phosphatidylserine decarboxylase beta chain]; catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 1329791 psd 8208793 psd Helicobacter pylori B38 phosphatidylserine decarboxylase YP_003058007.1 1328988 R 592205 CDS YP_003058008.1 254779902 8208880 complement(1329785..1330291) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1330291 8208880 HELPY_1348 Helicobacter pylori B38 hypothetical protein YP_003058008.1 1329785 R 592205 CDS YP_003058009.1 254779903 8208185 complement(1330304..1330798) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1330798 8208185 HELPY_1349 Helicobacter pylori B38 hypothetical protein YP_003058009.1 1330304 R 592205 CDS YP_003058010.1 254779904 8208186 complement(1330791..1331675) 1 NC_012973.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 1331675 ubiA 8208186 ubiA Helicobacter pylori B38 prenyltransferase YP_003058010.1 1330791 R 592205 CDS YP_003058011.1 254779905 8209070 complement(1331702..1332931) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; DNA competence protein; membrane protein 1332931 8209070 HELPY_1351 Helicobacter pylori B38 DNA competence protein; membrane protein YP_003058011.1 1331702 R 592205 CDS YP_003058012.1 254779906 8208187 complement(1333012..1334472) 1 NC_012973.1 unwinds double stranded DNA; replicative DNA helicase 1334472 dnaB 8208187 dnaB Helicobacter pylori B38 replicative DNA helicase YP_003058012.1 1333012 R 592205 CDS YP_003058013.1 254779907 8208463 complement(1334483..1335883) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1335883 8208463 HELPY_1353 Helicobacter pylori B38 hypothetical protein YP_003058013.1 1334483 R 592205 CDS YP_003058014.1 254779908 8208188 complement(1335886..1337004) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1337004 8208188 HELPY_1354 Helicobacter pylori B38 hypothetical protein YP_003058014.1 1335886 R 592205 CDS YP_003058015.1 254779909 8208189 complement(1337054..1337695) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type r : regulator; transcriptional regulatory protein 1337695 8208189 HELPY_1355 Helicobacter pylori B38 transcriptional regulatory protein YP_003058015.1 1337054 R 592205 CDS YP_003058016.1 254779910 8208192 1340244..1343150 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type III restriction enzyme R protein 1343150 8208192 HELPY_1358 Helicobacter pylori B38 type III restriction enzyme R protein YP_003058016.1 1340244 D 592205 CDS YP_003058017.1 254779911 8208193 complement(1343207..1343953) 1 NC_012973.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1343953 mreC 8208193 mreC Helicobacter pylori B38 rod shape-determining protein MreC YP_003058017.1 1343207 R 592205 CDS YP_003058018.1 254779912 8208780 complement(1343957..1345000) 1 NC_012973.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1345000 mreB 8208780 mreB Helicobacter pylori B38 rod shape-determining protein MreB YP_003058018.1 1343957 R 592205 CDS YP_003058019.1 254779913 8208779 complement(1345042..1346388) 1 NC_012973.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1346388 clpX 8208779 clpX Helicobacter pylori B38 ATP-dependent protease ATP-binding subunit ClpX YP_003058019.1 1345042 R 592205 CDS YP_003058020.1 254779914 8208429 complement(1346390..1347202) 1 NC_012973.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1347202 lpxA 8208429 lpxA Helicobacter pylori B38 UDP-N-acetylglucosamine acyltransferase YP_003058020.1 1346390 R 592205 CDS YP_003058021.1 254779915 8208738 complement(1347205..1347684) 1 NC_012973.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1347684 fabZ 8208738 fabZ Helicobacter pylori B38 (3R)-hydroxymyristoyl-ACP dehydratase YP_003058021.1 1347205 R 592205 CDS YP_003058022.1 254779916 8208497 complement(1347866..1348267) 1 NC_012973.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1348267 8208497 HELPY_1364 Helicobacter pylori B38 flagellar assembly protein FliW YP_003058022.1 1347866 R 592205 CDS YP_003058023.1 254779917 8208194 1348662..1349324 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1349324 8208194 HELPY_1365 Helicobacter pylori B38 hypothetical protein YP_003058023.1 1348662 D 592205 CDS YP_003058024.1 254779918 8208195 1349367..1351844 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15606774, 11325926, 7961402; Product type e : enzyme; ATP-dependent protease La 1351844 lon 8208195 lon Helicobacter pylori B38 ATP-dependent protease La YP_003058024.1 1349367 D 592205 CDS YP_003058025.1 254779919 8208735 1351841..1352680 1 NC_012973.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1352680 tyrA 8208735 tyrA Helicobacter pylori B38 prephenate dehydrogenase YP_003058025.1 1351841 D 592205 CDS YP_003058026.1 254779920 8209068 1352716..1352949 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1352949 8209068 HELPY_1368 Helicobacter pylori B38 hypothetical protein YP_003058026.1 1352716 D 592205 CDS YP_003058027.1 254779921 8208196 complement(1353008..1353871) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; DNA/RNA endonuclease G (nucG) 1353871 8208196 HELPY_1369 Helicobacter pylori B38 DNA/RNA endonuclease G (nucG) YP_003058027.1 1353008 R 592205 CDS YP_003058028.1 254779922 8208197 complement(1354142..1356022) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426350; Product type pe : enzyme; type III restriction enzyme M protein 1356022 8208197 HELPY_1370 Helicobacter pylori B38 type III restriction enzyme M protein YP_003058028.1 1354142 R 592205 CDS YP_003058029.1 254779923 8208198 complement(1356016..1358562) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426350; Product type pe : enzyme; type III restriction enzyme R protein 1358562 8208198 HELPY_1371 Helicobacter pylori B38 type III restriction enzyme R protein YP_003058029.1 1356016 R 592205 CDS YP_003058030.1 254779924 8208199 1358767..1359615 1 NC_012973.1 catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1359615 bioB 8208199 bioB Helicobacter pylori B38 biotin synthase YP_003058030.1 1358767 D 592205 CDS YP_003058031.1 254779925 8208405 1359615..1360493 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15764599, 10625642; Product type e : enzyme; ribonuclease N 1360493 rbn 8208405 rbn Helicobacter pylori B38 ribonuclease N YP_003058031.1 1359615 D 592205 CDS YP_003058033.1 254779926 8208202 1367410..1368315 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1368315 8208202 HELPY_1380 Helicobacter pylori B38 hypothetical protein YP_003058033.1 1367410 D 592205 CDS YP_003058034.1 254779927 8208203 complement(1368435..1368881) 1 NC_012973.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1368881 queF 8208203 queF Helicobacter pylori B38 7-cyano-7-deazaguanine reductase YP_003058034.1 1368435 R 592205 CDS YP_003058035.1 254779928 8208900 1368941..1369282 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1369282 8208900 HELPY_1382 Helicobacter pylori B38 hypothetical protein YP_003058035.1 1368941 D 592205 CDS YP_003058036.1 254779929 8208204 1369383..1370186 1 NC_012973.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1370186 miaA 8208204 miaA Helicobacter pylori B38 tRNA delta(2)-isopentenylpyrophosphate transferase YP_003058036.1 1369383 D 592205 CDS YP_003058037.1 254779930 8208757 1370187..1371290 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9334165; Product type pe : enzyme; lipopolysaccharide biosynthesis protein; LPS glycosyltransferase 1371290 8208757 HELPY_1384 Helicobacter pylori B38 lipopolysaccharide biosynthesis protein; LPS glycosyltransferase YP_003058037.1 1370187 D 592205 CDS YP_003058038.1 254779931 8208207 complement(1373058..1373837) 1 NC_012973.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1373837 murB 8208207 murB Helicobacter pylori B38 UDP-N-acetylenolpyruvoylglucosamine reductase YP_003058038.1 1373058 R 592205 CDS YP_003058039.1 254779932 8208784 complement(1373841..1374107) 1 NC_012973.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1374107 fliQ 8208784 fliQ Helicobacter pylori B38 flagellar biosynthesis protein FliQ YP_003058039.1 1373841 R 592205 CDS YP_003058040.1 254779933 8208543 complement(1374118..1375422) 1 NC_012973.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1375422 fliI 8208543 fliI Helicobacter pylori B38 flagellum-specific ATP synthase YP_003058040.1 1374118 R 592205 CDS YP_003058041.1 254779934 8208538 complement(1375423..1376337) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type IV secretion system ATPase 1376337 8208538 HELPY_1390 Helicobacter pylori B38 type IV secretion system ATPase YP_003058041.1 1375423 R 592205 CDS YP_003058042.1 254779935 8208208 complement(1376354..1379116) 1 NC_012973.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1379116 ileS 8208208 ileS Helicobacter pylori B38 isoleucyl-tRNA synthetase YP_003058042.1 1376354 R 592205 CDS YP_003058043.1 254779936 8208708 complement(1379141..1379395) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; RNA binding protein 1379395 8208708 HELPY_1392 Helicobacter pylori B38 RNA binding protein YP_003058043.1 1379141 R 592205 CDS YP_003058044.1 254779937 8208209 1379497..1380117 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1380117 8208209 HELPY_1393 Helicobacter pylori B38 hypothetical protein YP_003058044.1 1379497 D 592205 CDS YP_003058045.1 254779938 8208212 complement(1381384..1381605) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1381605 8208212 HELPY_1396 Helicobacter pylori B38 hypothetical protein YP_003058045.1 1381384 R 592205 CDS YP_003058046.1 254779939 8208213 complement(1381812..1382885) 1 NC_012973.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1382885 8208213 HELPY_1397 Helicobacter pylori B38 ribosomal RNA large subunit methyltransferase N YP_003058046.1 1381812 R 592205 CDS YP_003058047.1 254779940 8208214 complement(1382882..1383865) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16199563, 11956197; Product type pe : enzyme; phosphosugar isomerase 1383865 8208214 HELPY_1398 Helicobacter pylori B38 phosphosugar isomerase YP_003058047.1 1382882 R 592205 CDS YP_003058048.1 254779941 8208215 complement(1383855..1385933) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15831787; Product type e : enzyme; ribonuclease J 1385933 rnjA 8208215 rnjA Helicobacter pylori B38 ribonuclease J YP_003058048.1 1383855 R 592205 CDS YP_003058049.1 254779942 8208931 complement(1385971..1386786) 1 NC_012973.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1386786 ksgA 8208931 ksgA Helicobacter pylori B38 dimethyladenosine transferase YP_003058049.1 1385971 R 592205 CDS YP_003058050.1 254779943 8208726 1387050..1387295 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1387295 8208726 HELPY_1401 Helicobacter pylori B38 hypothetical protein YP_003058050.1 1387050 D 592205 CDS YP_003058051.1 254779944 8208216 complement(1387748..1388836) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type I restriction enzyme specificity protein 1388836 8208216 HELPY_1402 Helicobacter pylori B38 type I restriction enzyme specificity protein YP_003058051.1 1387748 R 592205 CDS YP_003058052.1 254779945 8208217 complement(1388878..1389759) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 94042872, 7868604; Product type e : enzyme; formyltetrahydrofolate deformylase 1389759 purU 8208217 purU Helicobacter pylori B38 formyltetrahydrofolate deformylase YP_003058052.1 1388878 R 592205 CDS YP_003058053.1 254779946 8208888 complement(1389762..1390640) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1598279, 15819627, 12791143, 86250892, 87222172; Product type e : enzyme; Signal peptide protease IV (Protease IV) (Endopeptidase IV) 1390640 sppA 8208888 sppA Helicobacter pylori B38 Signal peptide protease IV (Protease IV) (Endopeptidase IV) YP_003058053.1 1389762 R 592205 CDS YP_003058054.1 254779947 8209019 1390711..1390968 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1390968 8209019 HELPY_1405 Helicobacter pylori B38 hypothetical protein YP_003058054.1 1390711 D 592205 CDS YP_003058055.1 254779948 8208218 1391219..1391905 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1391905 8208218 HELPY_1406 Helicobacter pylori B38 hypothetical protein YP_003058055.1 1391219 D 592205 CDS YP_003058056.1 254779949 8208219 1391916..1393085 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1393085 8208219 HELPY_1407 Helicobacter pylori B38 hypothetical protein YP_003058056.1 1391916 D 592205 CDS YP_003058057.1 254779950 8208220 1393095..1393376 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1393376 8208220 HELPY_1408 Helicobacter pylori B38 hypothetical protein YP_003058057.1 1393095 D 592205 CDS YP_003058058.1 254779951 8208315 complement(1395910..1396689) 1 NC_012973.1 Evidence 4b : Only in Helicobacter genus; hypothetical protein 1396689 8208315 HELPY_1411 Helicobacter pylori B38 hypothetical protein YP_003058058.1 1395910 R 592205 CDS YP_003058059.1 254779952 8208222 1396808..1397299 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15479239, 12089032, 9748346, 9268657, 8022278; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase 1397299 ppiB 8208222 ppiB Helicobacter pylori B38 peptidyl-prolyl cis-trans isomerase YP_003058059.1 1396808 D 592205 CDS YP_003058060.1 254779953 8208868 1397318..1397548 1 NC_012973.1 affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator 1397548 csrA 8208868 csrA Helicobacter pylori B38 carbon storage regulator YP_003058060.1 1397318 D 592205 CDS YP_003058061.1 254779954 8208443 1397545..1398351 1 NC_012973.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1398351 ispE 8208443 ispE Helicobacter pylori B38 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_003058061.1 1397545 D 592205 CDS YP_003058062.1 254779955 8208718 1398348..1398806 1 NC_012973.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1398806 smpB 8208718 smpB Helicobacter pylori B38 SsrA-binding protein YP_003058062.1 1398348 D 592205 CDS YP_003058063.1 254779956 8209014 1398812..1399264 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; Biopolymer transport protein ExbD/TolR; membrane protein 1399264 exbD3 8209014 exbD3 Helicobacter pylori B38 Biopolymer transport protein ExbD/TolR; membrane protein YP_003058063.1 1398812 D 592205 CDS YP_003058064.1 254779957 8208492 1399275..1399676 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; Biopolymer transport accessory protein ExbD/TolR 1399676 exbB3 8208492 exbB3 Helicobacter pylori B38 Biopolymer transport accessory protein ExbD/TolR YP_003058064.1 1399275 D 592205 CDS YP_003058065.1 254779958 8208489 1399748..1399882 1 NC_012973.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1399882 rpmH 8208489 rpmH Helicobacter pylori B38 50S ribosomal protein L34 YP_003058065.1 1399748 D 592205 CDS YP_003058066.1 254779959 8208967 1399842..1400327 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12799461, 11376143, 9180701, 1689306, 1374553; Product type e : enzyme; ribonuclease P 1400327 rnpA 8208967 rnpA Helicobacter pylori B38 ribonuclease P YP_003058066.1 1399842 D 592205 CDS YP_003058067.1 254779960 8208932 1400314..1400667 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1400667 8208932 HELPY_1419 Helicobacter pylori B38 hypothetical protein YP_003058067.1 1400314 D 592205 CDS YP_003058068.1 254779961 8208223 1400673..1402313 1 NC_012973.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1402313 8208223 HELPY_1420 Helicobacter pylori B38 inner membrane protein translocase component YidC YP_003058068.1 1400673 D 592205 CDS YP_003058069.1 254779962 8208224 1402313..1403110 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1403110 8208224 HELPY_1421 Helicobacter pylori B38 hypothetical protein YP_003058069.1 1402313 D 592205 CDS YP_003058070.1 254779963 8208225 1403103..1404455 1 NC_012973.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1404455 trmE 8208225 trmE Helicobacter pylori B38 tRNA modification GTPase TrmE YP_003058070.1 1403103 D 592205 CDS YP_003058071.1 254779964 8209029 1404655..1406895 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9430586, 9252185; Product type m : membrane component; outer membrane protein HomD 1406895 homD 8209029 homD Helicobacter pylori B38 outer membrane protein HomD YP_003058071.1 1404655 D 592205 CDS YP_003058072.1 254779965 8208647 complement(1406913..1407107) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1407107 8208647 HELPY_1424 Helicobacter pylori B38 hypothetical protein YP_003058072.1 1406913 R 592205 CDS YP_003058073.1 254779966 8208226 complement(1407485..1408396) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1408396 8208226 HELPY_1425 Helicobacter pylori B38 hypothetical protein YP_003058073.1 1407485 R 592205 CDS YP_003058074.1 254779967 8208227 complement(1408406..1408747) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1408747 8208227 HELPY_1426 Helicobacter pylori B38 hypothetical protein YP_003058074.1 1408406 R 592205 CDS YP_003058075.1 254779968 8208228 complement(1408755..1409282) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16484186, 1282312, 12738392, 11211867, 10816482, 7928954; Product type lp : lipoprotein; Membrane-associated lipoprotein 1409282 lpp20 8208228 lpp20 Helicobacter pylori B38 Membrane-associated lipoprotein YP_003058075.1 1408755 R 592205 CDS YP_003058076.1 254779969 8208737 complement(1409306..1409938) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1409938 8208737 HELPY_1428 Helicobacter pylori B38 hypothetical protein YP_003058076.1 1409306 R 592205 CDS YP_003058077.1 254779970 8208229 complement(1410298..1410612) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16354674, 12832786, 12399485, 11222594, 10671551; Product type f : factor; thioredoxin 1410612 trx2 8208229 trx2 Helicobacter pylori B38 thioredoxin YP_003058077.1 1410298 R 592205 CDS YP_003058078.1 254779971 8209061 complement(1410668..1411441) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16712869, 12762017, 12581659, 11720289, 10902565, 7612632; Product type e : enzyme; Ribosomal large subunit pseudouridine synthase B 1411441 rluB 8209061 rluB Helicobacter pylori B38 Ribosomal large subunit pseudouridine synthase B YP_003058078.1 1410668 R 592205 CDS YP_003058079.1 254779972 8208924 complement(1411438..1415073) 1 NC_012973.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1415073 dnaE 8208924 dnaE Helicobacter pylori B38 DNA polymerase III subunit alpha YP_003058079.1 1411438 R 592205 CDS YP_003058080.1 254779973 8208464 1415232..1416284 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8591033; Product type pe : enzyme; di-heme cytochrome c peroxidase 1416284 8208464 HELPY_1432 Helicobacter pylori B38 di-heme cytochrome c peroxidase YP_003058080.1 1415232 D 592205 CDS YP_003058081.1 254779974 8208230 complement(1416581..1417168) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1417168 8208230 HELPY_1434 Helicobacter pylori B38 hypothetical protein YP_003058081.1 1416581 R 592205 CDS YP_003058082.1 254779975 8208231 complement(1417180..1417857) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1417857 8208231 HELPY_1435 Helicobacter pylori B38 hypothetical protein YP_003058082.1 1417180 R 592205 CDS YP_003058083.1 254779976 8208232 complement(1417860..1418675) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9658016, 8367727; Product type t : transporter; ABC transporter substrate-binding protein 1418675 8208232 HELPY_1436 Helicobacter pylori B38 ABC transporter substrate-binding protein YP_003058083.1 1417860 R 592205 CDS YP_003058084.1 254779977 8208233 complement(1418660..1419448) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10518715; Product type t : transporter; ABC transporter ATP-binding protein 1419448 8208233 HELPY_1437 Helicobacter pylori B38 ABC transporter ATP-binding protein YP_003058084.1 1418660 R 592205 CDS YP_003058085.1 254779978 8208234 complement(1419445..1420578) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9658016, 8367727; Product type t : transporter; ABC transporter permease 1420578 8208234 HELPY_1438 Helicobacter pylori B38 ABC transporter permease YP_003058085.1 1419445 R 592205 CDS YP_003058086.1 254779979 8208235 1420713..1421408 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; outer membrane protein 1421408 8208235 HELPY_1439 Helicobacter pylori B38 outer membrane protein YP_003058086.1 1420713 D 592205 CDS YP_003058087.1 254779980 8208236 complement(1421413..1422435) 1 NC_012973.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1422435 ilvE 8208236 ilvE Helicobacter pylori B38 branched-chain amino acid aminotransferase YP_003058087.1 1421413 R 592205 CDS YP_003058088.1 254779981 8208710 complement(1422487..1423233) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 10454640; Product type m : membrane component; outer membrane protein HorJ 1423233 horJ 8208710 horJ Helicobacter pylori B38 outer membrane protein HorJ YP_003058088.1 1422487 R 592205 CDS YP_003058089.1 254779982 8208672 complement(1423348..1426017) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16421093, 14712068, 12649320, 11283163, 8451181; Product type e : enzyme; DNA polymerase I (DNA nucleotidyltransferase (DNA-directed)) 1426017 polA 8208672 polA Helicobacter pylori B38 DNA polymerase I (DNA nucleotidyltransferase (DNA-directed)) YP_003058089.1 1423348 R 592205 CDS YP_003058090.1 254779983 8208239 complement(1429413..1429988) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1429988 8208239 HELPY_1446 Helicobacter pylori B38 hypothetical protein YP_003058090.1 1429413 R 592205 CDS YP_003058091.1 254779984 8208240 complement(1429976..1430551) 1 NC_012973.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1430551 tmk 8208240 tmk Helicobacter pylori B38 thymidylate kinase YP_003058091.1 1429976 R 592205 CDS YP_003058092.1 254779985 8209043 complement(1430553..1431026) 1 NC_012973.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1431026 coaD 8209043 coaD Helicobacter pylori B38 phosphopantetheine adenylyltransferase YP_003058092.1 1430553 R 592205 CDS YP_003058093.1 254779986 8208725 complement(1431026..1431589) 1 NC_012973.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1431589 8208725 HELPY_1449 Helicobacter pylori B38 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_003058093.1 1431026 R 592205 CDS YP_003058094.1 254779987 8208241 complement(1431599..1432255) 1 NC_012973.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1432255 flgA 8208241 flgA Helicobacter pylori B38 flagellar basal body P-ring biosynthesis protein FlgA YP_003058094.1 1431599 R 592205 CDS YP_003058095.1 254779988 8208242 complement(1432252..1434297) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16135232, 15375374, 12527299, 11004168, 11879732; Product type e : enzyme; DNA helicase II (UvrD) 1434297 uvrD 8208242 uvrD Helicobacter pylori B38 DNA helicase II (UvrD) YP_003058095.1 1432252 R 592205 CDS YP_003058096.1 254779989 8209086 complement(1434297..1436831) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1436831 8209086 HELPY_1452 Helicobacter pylori B38 hypothetical protein YP_003058096.1 1434297 R 592205 CDS YP_003058097.1 254779990 8208243 complement(1436841..1438088) 1 NC_012973.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1438088 serS 8208243 serS Helicobacter pylori B38 seryl-tRNA synthetase YP_003058097.1 1436841 R 592205 CDS YP_003058098.1 254779991 8209012 complement(1438089..1438886) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11380987, 7987228; Product type pe : enzyme; nitrilase/cyanide hydratase 1438886 8209012 HELPY_1454 Helicobacter pylori B38 nitrilase/cyanide hydratase YP_003058098.1 1438089 R 592205 CDS YP_003058099.1 254779992 8208244 complement(1438890..1439150) 1 NC_012973.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1439150 8208244 HELPY_1455 Helicobacter pylori B38 exodeoxyribonuclease VII small subunit YP_003058099.1 1438890 R 592205 CDS YP_003058100.1 254779993 8208245 complement(1439160..1439900) 1 NC_012973.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1439900 ubiE 8208245 ubiE Helicobacter pylori B38 ubiquinone/menaquinone biosynthesis methyltransferase YP_003058100.1 1439160 R 592205 CDS YP_003058101.1 254779994 8209072 complement(1439910..1440356) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1440356 8209072 HELPY_1457 Helicobacter pylori B38 hypothetical protein YP_003058101.1 1439910 R 592205 CDS YP_003058102.1 254779995 8208246 complement(1440367..1440939) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1440939 8208246 HELPY_1458 Helicobacter pylori B38 hypothetical protein YP_003058102.1 1440367 R 592205 CDS YP_003058103.1 254779996 8208247 complement(1440926..1442056) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 1442056 8208247 HELPY_1459 Helicobacter pylori B38 ABC transporter permease YP_003058103.1 1440926 R 592205 CDS YP_003058104.1 254779997 8208248 complement(1442053..1443150) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; ABC transporter permease 1443150 8208248 HELPY_1460 Helicobacter pylori B38 ABC transporter permease YP_003058104.1 1442053 R 592205 CDS YP_003058105.1 254779998 8208249 complement(1443162..1444151) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pt : transporter; hypothetical protein 1444151 8208249 HELPY_1461 Helicobacter pylori B38 hypothetical protein YP_003058105.1 1443162 R 592205 CDS YP_003058106.1 254779999 8208250 complement(1444163..1445695) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane transporter 1445695 8208250 HELPY_1462 Helicobacter pylori B38 outer membrane transporter YP_003058106.1 1444163 R 592205 CDS YP_003058107.1 254780000 8208251 complement(1445692..1447041) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16177343, 10531273; Product type pm : membrane component; TlyC-like hemolysin; membrane protein 1447041 8208251 HELPY_1463 Helicobacter pylori B38 TlyC-like hemolysin; membrane protein YP_003058107.1 1445692 R 592205 CDS YP_003058108.1 254780001 8208252 complement(1447144..1448745) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7732001; Product type t : transporter; transporter; phosphate transporter; membrane protein 1448745 8208252 HELPY_1464 Helicobacter pylori B38 transporter; phosphate transporter; membrane protein YP_003058108.1 1447144 R 592205 CDS YP_003058109.1 254780002 8208253 1448886..1449155 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8875867, 8048161; Product type pf : factor; nifU-like protein 1449155 8208253 HELPY_1465 Helicobacter pylori B38 nifU-like protein YP_003058109.1 1448886 D 592205 CDS YP_003058110.1 254780003 8208254 1449167..1449778 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1449778 8208254 HELPY_1466 Helicobacter pylori B38 hypothetical protein YP_003058110.1 1449167 D 592205 CDS YP_003058111.1 254780004 8208255 1449782..1451125 1 NC_012973.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1451125 murE 8208255 murE Helicobacter pylori B38 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_003058111.1 1449782 D 592205 CDS YP_003058112.1 254780005 8208787 1451129..1452079 1 NC_012973.1 Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1452079 tal 8208787 tal Helicobacter pylori B38 transaldolase YP_003058112.1 1451129 D 592205 CDS YP_003058113.1 254780006 8209024 1452134..1452670 1 NC_012973.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1452670 rplY 8209024 rplY Helicobacter pylori B38 50S ribosomal protein L25/general stress protein Ctc YP_003058113.1 1452134 D 592205 CDS YP_003058114.1 254780007 8208961 1452680..1453240 1 NC_012973.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1453240 pth 8208961 pth Helicobacter pylori B38 peptidyl-tRNA hydrolase YP_003058114.1 1452680 D 592205 CDS YP_003058115.1 254780008 8208884 1453250..1454317 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; permease; membrane protein 1454317 8208884 HELPY_1471 Helicobacter pylori B38 permease; membrane protein YP_003058115.1 1453250 D 592205 CDS YP_003058116.1 254780009 8208256 1454438..1455358 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1455358 8208256 HELPY_1472 Helicobacter pylori B38 hypothetical protein YP_003058116.1 1454438 D 592205 CDS YP_003058117.1 254780010 8208257 1455435..1455608 1 NC_012973.1 Evidence 6 : Doubtful CDS; hypothetical protein 1455608 8208257 HELPY_1473 Helicobacter pylori B38 hypothetical protein YP_003058117.1 1455435 D 592205 CDS YP_003058118.1 254780011 8208258 complement(1455671..1456837) 1 NC_012973.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HorK 1456837 hopK 8208258 hopK Helicobacter pylori B38 outer membrane protein HorK YP_003058118.1 1455671 R 592205 CDS YP_003058119.1 254780012 8208659 1457016..1457453 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1457453 8208659 HELPY_1475 Helicobacter pylori B38 hypothetical protein YP_003058119.1 1457016 D 592205 CDS YP_003058120.1 254780013 8208259 complement(1457450..1459801) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16804172, 9440521, 9244252, 9398888, 16269744, 12974640, 9188683; Product type t : transporter; ATPase, P-type copper-transporter; membrane protein 1459801 copA 8208259 copA Helicobacter pylori B38 ATPase, P-type copper-transporter; membrane protein YP_003058120.1 1457450 R 592205 CDS YP_003058121.1 254780014 8208438 complement(1459827..1460543) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1460543 8208438 HELPY_1477 Helicobacter pylori B38 hypothetical protein YP_003058121.1 1459827 R 592205 CDS YP_003058122.1 254780015 8208260 complement(1460525..1461559) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11024263, 9068650; Product type e : enzyme; Riboflavin biosynthesis protein RibD 1461559 ribD 8208260 ribD Helicobacter pylori B38 Riboflavin biosynthesis protein RibD YP_003058122.1 1460525 R 592205 CDS YP_003058123.1 254780016 8208920 complement(1461556..1462782) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12664155, 2254324, 8596452, 2017136; Product type t : transporter; transporter, GltS family; membrane protein 1462782 gltS 8208920 gltS Helicobacter pylori B38 transporter, GltS family; membrane protein YP_003058123.1 1461556 R 592205 CDS YP_003058124.1 254780017 8208590 1462868..1464067 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17513436; Product type pe : enzyme; saccharopine dehydrogenase 1464067 8208590 HELPY_1480 Helicobacter pylori B38 saccharopine dehydrogenase YP_003058124.1 1462868 D 592205 CDS YP_003058125.1 254780018 8208261 complement(1464077..1465453) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16645308, 16143852, 15134648, 12709048, 11734195, 9785959; Product type c : carrier; ferredoxin-like protein 1465453 8208261 HELPY_1481 Helicobacter pylori B38 ferredoxin-like protein YP_003058125.1 1464077 R 592205 CDS YP_003058126.1 254780019 8208262 1465559..1466221 1 NC_012973.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1466221 8208262 HELPY_1482 Helicobacter pylori B38 glycerol-3-phosphate acyltransferase PlsY YP_003058126.1 1465559 D 592205 CDS YP_003058127.1 254780020 8208263 1466218..1466571 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9651328; Product type e : enzyme; Dihydroneopterin aldolase 1466571 folB 8208263 folB Helicobacter pylori B38 Dihydroneopterin aldolase YP_003058127.1 1466218 D 592205 CDS YP_003058128.1 254780021 8208548 1466588..1466881 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1466881 8208548 HELPY_1484 Helicobacter pylori B38 hypothetical protein YP_003058128.1 1466588 D 592205 CDS YP_003058129.1 254780022 8208264 1467035..1469674 1 NC_012973.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12704139, 12165031, 16914236; Product type m : membrane component; Iron-regulated outer membrane protein 1469674 frpB3 8208264 frpB3 Helicobacter pylori B38 Iron-regulated outer membrane protein YP_003058129.1 1467035 D 592205 CDS YP_003058130.1 254780023 8208559 1469901..1471061 1 NC_012973.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1471061 selA 8208559 selA Helicobacter pylori B38 selenocysteine synthase YP_003058130.1 1469901 D 592205 CDS YP_003058131.1 254780024 8209009 1471158..1472345 1 NC_012973.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1472345 nusA 8209009 nusA Helicobacter pylori B38 transcription elongation factor NusA YP_003058131.1 1471158 D 592205 CDS YP_003058132.1 254780025 8208266 complement(1473330..1473686) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1473686 8208266 HELPY_1490 Helicobacter pylori B38 hypothetical protein YP_003058132.1 1473330 R 592205 CDS YP_003058133.1 254780026 8208267 complement(1474270..1478010) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type pe : enzyme; type IIS restriction-modification protein 1478010 8208267 HELPY_1491 Helicobacter pylori B38 type IIS restriction-modification protein YP_003058133.1 1474270 R 592205 CDS YP_003058134.1 254780027 8208268 complement(1478213..1481119) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12426350, 2837577; Product type e : enzyme; type III R-M system restriction enzyme 1481119 res 8208268 res Helicobacter pylori B38 type III R-M system restriction enzyme YP_003058134.1 1478213 R 592205 CDS YP_003058135.1 254780028 8208768 complement(1483100..1484971) 1 NC_012973.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1484971 recG 8208768 recG Helicobacter pylori B38 ATP-dependent DNA helicase RecG YP_003058135.1 1483100 R 592205 CDS YP_003058136.1 254780029 8208906 1485050..1485400 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1485400 8208906 HELPY_1496 Helicobacter pylori B38 hypothetical protein YP_003058136.1 1485050 D 592205 CDS YP_003058137.1 254780030 8208269 1485404..1486039 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein 1486039 8208269 HELPY_1497 Helicobacter pylori B38 outer membrane protein YP_003058137.1 1485404 D 592205 CDS YP_003058138.1 254780031 8208270 complement(1486036..1486788) 1 NC_012973.1 AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III 1486788 8208270 HELPY_1498 Helicobacter pylori B38 exodeoxyribonuclease III YP_003058138.1 1486036 R 592205 CDS YP_003058139.1 254780032 8208325 complement(1486968..1488407) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16436074, 16428391, 15516585, 12933898, 12868652, 1148912, 1086902; Product type f : factor; DNA transformation competence protein ComH 1488407 comH 8208325 comH Helicobacter pylori B38 DNA transformation competence protein ComH YP_003058139.1 1486968 R 592205 CDS YP_003058140.1 254780033 8208436 complement(1488636..1490003) 1 NC_012973.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1490003 dnaA 8208436 dnaA Helicobacter pylori B38 chromosomal replication initiation protein YP_003058140.1 1488636 R 592205 CDS YP_003058141.1 254780034 8208462 1490156..1490698 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9058966; Product type e : enzyme; purine nucleoside phosphorylase PunB 1490698 8208462 HELPY_1501 Helicobacter pylori B38 purine nucleoside phosphorylase PunB YP_003058141.1 1490156 D 592205 CDS YP_003058142.1 254780035 8208272 1490741..1490980 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1490980 8208272 HELPY_1502 Helicobacter pylori B38 hypothetical protein YP_003058142.1 1490741 D 592205 CDS YP_003058143.1 254780036 8208273 1490981..1492774 1 NC_012973.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1492774 glmS 8208273 glmS Helicobacter pylori B38 glucosamine--fructose-6-phosphate aminotransferase YP_003058143.1 1490981 D 592205 CDS YP_003058144.1 254780037 8208586 1492796..1493422 1 NC_012973.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1493422 thyX 8208586 thyX Helicobacter pylori B38 FAD-dependent thymidylate synthase YP_003058144.1 1492796 D 592205 CDS YP_003058145.1 254780038 8209036 1493576..1493668 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1493668 8209036 HELPY_1505 Helicobacter pylori B38 hypothetical protein YP_003058145.1 1493576 D 592205 CDS YP_003058146.1 254780039 8208274 complement(1493750..1494871) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type pe : enzyme; type I R-M system specificity subunit 1494871 8208274 HELPY_1506 Helicobacter pylori B38 type I R-M system specificity subunit YP_003058146.1 1493750 R 592205 CDS YP_003058147.1 254780040 8208275 complement(1494880..1497330) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type e : enzyme; type I restriction-modification enzyme subunit M 1497330 hsdM3 8208275 hsdM3 Helicobacter pylori B38 type I restriction-modification enzyme subunit M YP_003058147.1 1494880 R 592205 CDS YP_003058148.1 254780041 8208687 1497398..1500364 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type e : enzyme; type I restriction-modification enzyme subunit R 1500364 hsdR3 8208687 hsdR3 Helicobacter pylori B38 type I restriction-modification enzyme subunit R YP_003058148.1 1497398 D 592205 CDS YP_003058149.1 254780042 8208688 1500364..1501071 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1501071 8208688 HELPY_1509 Helicobacter pylori B38 hypothetical protein YP_003058149.1 1500364 D 592205 CDS YP_003058150.1 254780043 8208276 complement(1501170..1503698) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10713425, 12165031, 16718597, 16333751, 16193283, 12948487, 12732308; Product type t : transporter; Iron(III) dicitrate transport protein FecA 1503698 fecA3 8208276 fecA3 Helicobacter pylori B38 Iron(III) dicitrate transport protein FecA YP_003058150.1 1501170 R 592205 CDS YP_003058151.1 254780044 8208502 complement(1504232..1505200) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16672598, 15128304, 11717441, 10931887, 10572136, 7540694; Product type e : enzyme; Arginase 1505200 rocF 8208502 rocF Helicobacter pylori B38 Arginase YP_003058151.1 1504232 R 592205 CDS YP_003058152.1 254780045 8208934 1505404..1506546 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16816198, 12193615, 9168598; Product type e : enzyme; Alanine dehydrogenase 1506546 ald 8208934 ald Helicobacter pylori B38 Alanine dehydrogenase YP_003058152.1 1505404 D 592205 CDS YP_003058153.1 254780046 8208372 1506670..1508421 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1508421 8208372 HELPY_1514 Helicobacter pylori B38 hypothetical protein YP_003058153.1 1506670 D 592205 CDS YP_003058154.1 254780047 8208277 complement(1508432..1509160) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; Product type m : membrane component; outer membrane protein HorL 1509160 horL 8208277 horL Helicobacter pylori B38 outer membrane protein HorL YP_003058154.1 1508432 R 592205 CDS YP_003058155.1 254780048 8208673 1509346..1510200 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511117, 11488932, 11006082; Product type e : enzyme; inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase) 1510200 ppnK 8208673 ppnK Helicobacter pylori B38 inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase) YP_003058155.1 1509346 D 592205 CDS YP_003058156.1 254780049 8208871 1510221..1511795 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16780573, 16079351, 15948952, 15186413, 12670973, 11807051; Product type cp : cell process; DNA repair protein 1511795 recN 8208871 recN Helicobacter pylori B38 DNA repair protein YP_003058156.1 1510221 D 592205 CDS YP_003058157.1 254780050 8208908 1511792..1513099 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fibronectin/fibrinogen-binding protein 1513099 8208908 HELPY_1518 Helicobacter pylori B38 fibronectin/fibrinogen-binding protein YP_003058157.1 1511792 D 592205 CDS YP_003058158.1 254780051 8208278 1513118..1513414 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1513414 8208278 HELPY_1519 Helicobacter pylori B38 hypothetical protein YP_003058158.1 1513118 D 592205 CDS YP_003058159.1 254780052 8208279 1513749..1514027 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1514027 8208279 HELPY_1520 Helicobacter pylori B38 Hac prophage II protein YP_003058159.1 1513749 D 592205 CDS YP_003058160.1 254780053 8208280 1514027..1515151 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II integrase 1515151 8208280 HELPY_1521 Helicobacter pylori B38 Hac prophage II integrase YP_003058160.1 1514027 D 592205 CDS YP_003058161.1 254780054 8208281 1515148..1515288 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1515288 8208281 HELPY_1522 Helicobacter pylori B38 Hac prophage II protein YP_003058161.1 1515148 D 592205 CDS YP_003058162.1 254780055 8208282 1515363..1515683 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1515683 8208282 HELPY_1523 Helicobacter pylori B38 Hac prophage II protein YP_003058162.1 1515363 D 592205 CDS YP_003058163.1 254780056 8208283 1515670..1515810 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1515810 8208283 HELPY_1524 Helicobacter pylori B38 Hac prophage II protein YP_003058163.1 1515670 D 592205 CDS YP_003058164.1 254780057 8208284 1515811..1516740 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1516740 8208284 HELPY_1525 Helicobacter pylori B38 Hac prophage II protein YP_003058164.1 1515811 D 592205 CDS YP_003058165.1 254780058 8208285 1516951..1517241 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1517241 8208285 HELPY_1527 Helicobacter pylori B38 Hac prophage II protein YP_003058165.1 1516951 D 592205 CDS YP_003058166.1 254780059 8208287 complement(1517857..1519086) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 1519086 8208287 HELPY_1529 Helicobacter pylori B38 transposase, OrfB, ISHp609 YP_003058166.1 1517857 R 592205 CDS YP_003058167.1 254780060 8208288 complement(1519073..1519705) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 1519705 8208288 HELPY_1530 Helicobacter pylori B38 Serine recombinase-transposase, OrfA, ISHp609 YP_003058167.1 1519073 R 592205 CDS YP_003058168.1 254780061 8208289 complement(1519702..1519887) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1519887 8208289 HELPY_1531 Helicobacter pylori B38 hypothetical protein YP_003058168.1 1519702 R 592205 CDS YP_003058169.1 254780062 8208290 complement(1519889..1520146) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1520146 8208290 HELPY_1532 Helicobacter pylori B38 hypothetical protein YP_003058169.1 1519889 R 592205 CDS YP_003058170.1 254780063 8208292 1521000..1521977 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11777911, 10748053, 99369890, 16040986; Product type f : factor; hypothetical protein 1521977 hcpG 8208292 hcpG Helicobacter pylori B38 hypothetical protein YP_003058170.1 1521000 D 592205 CDS YP_003058171.1 254780064 8208618 complement(1522016..1522879) 1 NC_012973.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1522879 dnaQ 8208618 dnaQ Helicobacter pylori B38 DNA polymerase III subunit epsilon YP_003058171.1 1522016 R 592205 CDS YP_003058172.1 254780065 8208470 complement(1522857..1523510) 1 NC_012973.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1523510 rpe 8208470 rpe Helicobacter pylori B38 ribulose-phosphate 3-epimerase YP_003058172.1 1522857 R 592205 CDS YP_003058173.1 254780066 8208936 1523581..1524453 1 NC_012973.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1524453 fbp 8208936 fbp Helicobacter pylori B38 fructose-1,6-bisphosphatase YP_003058173.1 1523581 D 592205 CDS YP_003058174.1 254780067 8208499 1524453..1524656 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1524656 8208499 HELPY_1538 Helicobacter pylori B38 hypothetical protein YP_003058174.1 1524453 D 592205 CDS YP_003058175.1 254780068 8208293 1524669..1525565 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type pe : enzyme; N-6 Adenine-specific DNA methylase 1525565 8208293 HELPY_1539 Helicobacter pylori B38 N-6 Adenine-specific DNA methylase YP_003058175.1 1524669 D 592205 CDS YP_003058176.1 254780069 8208294 1525868..1526290 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1526290 8208294 HELPY_1540 Helicobacter pylori B38 hypothetical protein YP_003058176.1 1525868 D 592205 CDS YP_003058177.1 254780070 8208295 complement(1526407..1527264) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15262969, 12672829; Product type e : enzyme; Ubiquinol cytochrome c oxidoreductase, cytochrome c subunit 1527264 petC 8208295 petC Helicobacter pylori B38 Ubiquinol cytochrome c oxidoreductase, cytochrome c subunit YP_003058177.1 1526407 R 592205 CDS YP_003058178.1 254780071 8208850 complement(1527261..1528499) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15262969, 12672829; Product type e : enzyme; Ubiquinol cytochrome c oxidoreductase, cytochrome b subunit; membrane protein 1528499 petB 8208850 petB Helicobacter pylori B38 Ubiquinol cytochrome c oxidoreductase, cytochrome b subunit; membrane protein YP_003058178.1 1527261 R 592205 CDS YP_003058179.1 254780072 8208849 complement(1528510..1529013) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15262969, 12672829; Product type e : enzyme; Ubiquinol cytochrome c oxidoreductase, 2Fe-2S subunit 1529013 petA 8208849 petA Helicobacter pylori B38 Ubiquinol cytochrome c oxidoreductase, 2Fe-2S subunit YP_003058179.1 1528510 R 592205 CDS YP_003058180.1 254780073 8208848 complement(1529148..1532135) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16551743, 16511235, 16469698, 16309703, 15720542; Product type f : factor; transcription-repair coupling factor 1532135 mfd 8208848 mfd Helicobacter pylori B38 transcription-repair coupling factor YP_003058180.1 1529148 R 592205 CDS YP_003058181.1 254780074 8208756 complement(1532139..1532549) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1532549 8208756 HELPY_1545 Helicobacter pylori B38 hypothetical protein YP_003058181.1 1532139 R 592205 CDS YP_003058182.1 254780075 8208296 complement(1532468..1533406) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7523253, 9457886; Product type e : enzyme; Zn-metallopeptidase, M23 family 1533406 tagE1 8208296 tagE1 Helicobacter pylori B38 Zn-metallopeptidase, M23 family YP_003058182.1 1532468 R 592205 CDS YP_003058183.1 254780076 8209022 complement(1533415..1534344) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7523253, 9457886; Product type e : enzyme; Zn-metallopeptidase, M23 family 1534344 tagE2 8209022 tagE2 Helicobacter pylori B38 Zn-metallopeptidase, M23 family YP_003058183.1 1533415 R 592205 CDS YP_003058184.1 254780077 8209023 complement(1534341..1535516) 1 NC_012973.1 [Folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase); Dihydrofolate synthase]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8304196, 9618466; Product type e : enzyme; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 1535516 folC 8209023 folC Helicobacter pylori B38 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_003058184.1 1534341 R 592205 CDS YP_003058185.1 254780078 8208549 complement(1535506..1536018) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1536018 8208549 HELPY_1549 Helicobacter pylori B38 hypothetical protein YP_003058185.1 1535506 R 592205 CDS YP_003058186.1 254780079 8208297 complement(1536015..1538441) 1 NC_012973.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1538441 leuS 8208297 leuS Helicobacter pylori B38 leucyl-tRNA synthetase YP_003058186.1 1536015 R 592205 CDS YP_003058187.1 254780080 8208729 complement(1538448..1538786) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1538786 8208729 HELPY_1551 Helicobacter pylori B38 hypothetical protein YP_003058187.1 1538448 R 592205 CDS YP_003058188.1 254780081 8208298 complement(1538796..1539767) 1 NC_012973.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1539767 secF 8208298 secF Helicobacter pylori B38 preprotein translocase subunit SecF YP_003058188.1 1538796 R 592205 CDS YP_003058189.1 254780082 8209006 complement(1539776..1541353) 1 NC_012973.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1541353 secD 8209006 secD Helicobacter pylori B38 preprotein translocase subunit SecD YP_003058189.1 1539776 R 592205 CDS YP_003058190.1 254780083 8209004 complement(1541350..1541733) 1 NC_012973.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1541733 yajC 8209004 yajC Helicobacter pylori B38 preprotein translocase subunit YajC YP_003058190.1 1541350 R 592205 CDS YP_003058191.1 254780084 8209094 complement(1541781..1543130) 1 NC_012973.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1543130 nhaA 8209094 nhaA Helicobacter pylori B38 pH-dependent sodium/proton antiporter YP_003058191.1 1541781 R 592205 CDS YP_003058192.1 254780085 8208799 complement(1543121..1545958) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 91267926, 9288744; Product type e : enzyme; recombination protein RecB 1545958 pcrA 8208799 pcrA Helicobacter pylori B38 recombination protein RecB YP_003058192.1 1543121 R 592205 CDS YP_003058193.1 254780086 8208843 1546206..1547000 1 NC_012973.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1547000 rpsB 8208843 rpsB Helicobacter pylori B38 30S ribosomal protein S2 YP_003058193.1 1546206 D 592205 CDS YP_003058194.1 254780087 8208976 1547000..1548067 1 NC_012973.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1548067 tsf 8208976 tsf Helicobacter pylori B38 elongation factor Ts YP_003058194.1 1547000 D 592205 CDS YP_003058195.1 254780088 8209065 complement(1548514..1550361) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 83296957, 96404787, 98268991, 99058131, 98190796, 91207040; Product type e : enzyme; Penicillin-binding protein 3 1550361 pbp3 8209065 pbp3 Helicobacter pylori B38 Penicillin-binding protein 3 YP_003058195.1 1548514 R 592205 CDS YP_003058196.1 254780089 8208840 complement(1550517..1550846) 1 NC_012973.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1550846 fliE 8208840 fliE Helicobacter pylori B38 flagellar hook-basal body protein FliE YP_003058196.1 1550517 R 592205 CDS YP_003058197.1 254780090 8208534 complement(1550974..1551459) 1 NC_012973.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1551459 flgC 8208534 flgC Helicobacter pylori B38 flagellar basal body rod protein FlgC YP_003058197.1 1550974 R 592205 CDS YP_003058198.1 254780091 8208517 complement(1551472..1551894) 1 NC_012973.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1551894 flgB 8208517 flgB Helicobacter pylori B38 flagellar basal body rod protein FlgB YP_003058198.1 1551472 R 592205 CDS YP_003058199.1 254780092 8208516 1552099..1553265 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16040206, 15773984, 15752189, 15576787; Product type cp : cell process; cell division protein FtsW 1553265 ftsW 8208516 ftsW Helicobacter pylori B38 cell division protein FtsW YP_003058199.1 1552099 D 592205 CDS YP_003058200.1 254780093 8208566 complement(1553288..1554295) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter substrate-binding protein 1554295 8208566 HELPY_1564 Helicobacter pylori B38 ABC transporter substrate-binding protein YP_003058200.1 1553288 R 592205 CDS YP_003058201.1 254780094 8208299 1554535..1555131 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11843959, 15102813, 8041738; Product type e : enzyme; Alkyl hydroperoxide reductase 1555131 tsaA 8208299 tsaA Helicobacter pylori B38 Alkyl hydroperoxide reductase YP_003058201.1 1554535 D 592205 CDS YP_003058202.1 254780095 8209064 1555277..1556092 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12169620; Product type lp : lipoprotein; D-methionine-binding lipoprotein metQ (outer membrane lipoprotein 1) 1556092 metQ 8209064 metQ Helicobacter pylori B38 D-methionine-binding lipoprotein metQ (outer membrane lipoprotein 1) YP_003058202.1 1555277 D 592205 CDS YP_003058203.1 254780096 8208754 complement(1556572..1558338) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11181392; Product type e : enzyme; Penicillin-binding protein PBP2 1558338 pbp2 8208754 pbp2 Helicobacter pylori B38 Penicillin-binding protein PBP2 YP_003058203.1 1556572 R 592205 CDS YP_003058204.1 254780097 8208839 complement(1558319..1558762) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1558762 8208839 HELPY_1569 Helicobacter pylori B38 hypothetical protein YP_003058204.1 1558319 R 592205 CDS YP_003058205.1 254780098 8208300 complement(1558775..1559401) 1 NC_012973.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1559401 engB 8208300 engB Helicobacter pylori B38 ribosome biogenesis GTP-binding protein YsxC YP_003058205.1 1558775 R 592205 CDS YP_003058206.1 254780099 8208484 complement(1559398..1559949) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1559949 8208484 HELPY_1571 Helicobacter pylori B38 hypothetical protein YP_003058206.1 1559398 R 592205 CDS YP_003058207.1 254780100 8208301 complement(1559949..1560542) 1 NC_012973.1 Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1560542 8208301 HELPY_1572 Helicobacter pylori B38 hypothetical protein YP_003058207.1 1559949 R 592205 CDS YP_003058208.1 254780101 8208302 complement(1560517..1561011) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12639950; Product type e : enzyme; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1561011 kdsC 8208302 kdsC Helicobacter pylori B38 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_003058208.1 1560517 R 592205 CDS YP_003058209.1 254780102 8208724 complement(1561008..1561952) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3316191; Product type lp : lipoprotein; lipoprotein 1561952 8208724 HELPY_1574 Helicobacter pylori B38 lipoprotein YP_003058209.1 1561008 R 592205 CDS YP_003058210.1 254780103 8208303 complement(1561952..1563070) 1 NC_012973.1 Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15694856, 10469189, 10368145; Product type e : enzyme; Lytic murein transglycosylase D (Murein hydrolase D) 1563070 mltD 8208303 mltD Helicobacter pylori B38 Lytic murein transglycosylase D (Murein hydrolase D) YP_003058210.1 1561952 R 592205 CDS YP_003058211.1 254780104 8208761 complement(1563159..1563923) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10747959; Product type e : enzyme; Deoxyribonuclease 1563923 8208761 HELPY_1576 Helicobacter pylori B38 Deoxyribonuclease YP_003058211.1 1563159 R 592205 CDS YP_003058212.1 254780105 8208304 1563998..1564618 1 NC_012973.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1564618 ribC 8208304 ribC Helicobacter pylori B38 riboflavin synthase subunit alpha YP_003058212.1 1563998 D 592205 CDS YP_003058213.1 254780106 8208919 1564619..1564891 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1564891 8208919 HELPY_1578 Helicobacter pylori B38 hypothetical protein YP_003058213.1 1564619 D 592205 CDS YP_003058214.1 254780107 8208305 1564910..1565893 1 NC_012973.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 1565893 metN 8208305 metN Helicobacter pylori B38 DL-methionine transporter ATP-binding subunit YP_003058214.1 1564910 D 592205 CDS YP_003058215.1 254780108 8208360 1565895..1566542 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12218041, 9294450; Product type t : transporter; ABC transporter permease; D-and L-methionine transport protein; membrane protein 1566542 8208360 HELPY_1580 Helicobacter pylori B38 ABC transporter permease; D-and L-methionine transport protein; membrane protein YP_003058215.1 1565895 D 592205 CDS YP_003058216.1 254780109 8208306 complement(1566574..1567692) 1 NC_012973.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; LPS biosynthesis protein, glycosyltransferase 1567692 8208306 HELPY_1582 Helicobacter pylori B38 LPS biosynthesis protein, glycosyltransferase YP_003058216.1 1566574 R 592205 CDS YP_003058217.1 254780110 8208307 complement(1567741..1568169) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1568169 8208307 HELPY_1583 Helicobacter pylori B38 hypothetical protein YP_003058217.1 1567741 R 592205 CDS YP_003058218.1 254780111 8208308 complement(1568179..1568775) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein 1568775 8208308 HELPY_1584 Helicobacter pylori B38 hypothetical protein YP_003058218.1 1568179 R 592205 CDS YP_003058219.1 254780112 8208309 complement(1568772..1569782) 1 NC_012973.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15908345, 1575219, 11832520, 11700352, 10629198; Product type e : enzyme; UDP-phosphate N-acetylgalactosaminyl-1-phosphate transferase 1569782 wecA 8208309 wecA Helicobacter pylori B38 UDP-phosphate N-acetylgalactosaminyl-1-phosphate transferase YP_003058219.1 1568772 R 592205 CDS YP_003058220.1 254780113 8209092 1569918..1570706 1 NC_012973.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1570706 pdxJ 8209092 pdxJ Helicobacter pylori B38 pyridoxine 5'-phosphate synthase YP_003058220.1 1569918 D 592205 CDS YP_003058221.1 254780114 8208844 1570708..1571631 1 NC_012973.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1571631 pdxA 8208844 pdxA Helicobacter pylori B38 4-hydroxythreonine-4-phosphate dehydrogenase YP_003058221.1 1570708 D 592205 CDS YP_003058222.1 254780115 8208310 1571696..1572718 1 NC_012973.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1572718 8208310 HELPY_1588 Helicobacter pylori B38 DNA-binding/iron metalloprotein/AP endonuclease YP_003058222.1 1571696 D 592205 CDS YP_003058223.1 254780116 8208311 1572895..1573683 1 NC_012973.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1573683 flgG 8208311 flgG Helicobacter pylori B38 flagellar basal body rod protein FlgG YP_003058223.1 1572895 D 592205 CDS YP_003058224.1 254780117 8208522 complement(1573680..1574288) 1 NC_012973.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1574288 8208522 HELPY_1590 Helicobacter pylori B38 hypothetical protein YP_003058224.1 1573680 R 592205 CDS YP_003058225.1 254780118 8208312 complement(1574716..1574856) 1 NC_012973.1 Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1574856 8208312 HELPY_1591 Helicobacter pylori B38 hypothetical protein YP_003058225.1 1574716 R 592205 CDS YP_003058226.1 254780119 8208313 complement(1574941..1575702) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1575702 8208313 HELPY_1592 Helicobacter pylori B38 hypothetical protein YP_003058226.1 1574941 R 592205 CDS YP_003058227.1 254780120 8208314 complement(1575962..1576681) 1 NC_012973.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1576681 8208314 HELPY_1593 Helicobacter pylori B38 hypothetical protein YP_003058227.1 1575962 R 592205 CDS