-- dump date 20120504_150127 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 592205000001 SEQ_END SEQ_END NC_012973.1 1576758 1576758 DR NC_012973.1; contig end 1576758..1576758 Helicobacter pylori B38 YP_003056844.1 CDS nusB NC_012973.1 105 521 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(105..521) Helicobacter pylori B38 8209096 YP_003056845.1 CDS ribH NC_012973.1 523 993 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(523..993) Helicobacter pylori B38 8208824 YP_003056846.1 CDS kdsA NC_012973.1 1003 1833 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(1003..1833) Helicobacter pylori B38 8208921 YP_003056847.1 CDS icfA NC_012973.1 1820 2485 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15866214, 3049588, 9761692; Product type e : enzyme; Beta-carbonic anhydrase complement(1820..2485) Helicobacter pylori B38 8208722 YP_003056848.1 CDS pyrF NC_012973.1 2605 3288 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2605..3288 Helicobacter pylori B38 8208707 YP_003056849.1 CDS panC NC_012973.1 3289 4119 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3289..4119 Helicobacter pylori B38 8208896 YP_003056850.1 CDS hopZ NC_012973.1 5118 7130 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 18192681, 16322107, 16220040, 16173498, 15918181, 12454856, 11211867; Product type m : membrane component; outer membrane protein HopZ complement(5118..7130) Helicobacter pylori B38 8208349 YP_003056851.1 CDS groEL NC_012973.1 7478 9118 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(7478..9118) Helicobacter pylori B38 8208665 YP_003056852.1 CDS groES NC_012973.1 9144 9500 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(9144..9500) Helicobacter pylori B38 8208604 YP_003056853.1 CDS dnaG NC_012973.1 9787 11466 D synthesizes RNA primers at the replication forks; DNA primase 9787..11466 Helicobacter pylori B38 8208605 YP_003056854.1 CDS HELPY_0011 NC_012973.1 11463 12515 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 11463..12515 Helicobacter pylori B38 8208465 YP_003056855.1 CDS HELPY_0012 NC_012973.1 12605 13432 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 12605..13432 Helicobacter pylori B38 8207526 YP_003056856.1 CDS HELPY_0013 NC_012973.1 13578 13859 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 13578..13859 Helicobacter pylori B38 8207527 YP_003056857.1 CDS HELPY_0014 NC_012973.1 13859 14122 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 13859..14122 Helicobacter pylori B38 8207528 YP_003056858.1 CDS comB4 NC_012973.1 14124 16487 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16428391, 15133060, 12868652, 12668646, 11489125, 10383764, 10066547; Product type t : transporter; ATPase/DNA transfer protein 14124..16487 Helicobacter pylori B38 8207529 YP_003056859.1 CDS HELPY_0016 NC_012973.1 16670 18121 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 16670..18121 Helicobacter pylori B38 8208323 YP_003056860.1 CDS cheV1 NC_012973.1 18229 19194 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15664919, 15205568, 15130117, 14631875, 8809743, 8169224, 8169223; Product type r : regulator; Chemotaxis protein (Che V) 18229..19194 Helicobacter pylori B38 8207530 YP_003056861.1 CDS nspC NC_012973.1 19191 20408 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16009566, 1955861, 16237027; Product type e : enzyme; Carboxynorspermidine decarboxylase 19191..20408 Helicobacter pylori B38 8208420 YP_003056862.1 CDS HELPY_0019 NC_012973.1 20418 20990 R inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase complement(20418..20990) Helicobacter pylori B38 8208807 YP_003056863.1 CDS HELPY_0020 NC_012973.1 21001 22566 R attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase complement(21001..22566) Helicobacter pylori B38 8207531 YP_003056864.1 CDS HELPY_0021 NC_012973.1 22598 22738 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(22598..22738) Helicobacter pylori B38 8207532 YP_003056865.1 CDS hopD NC_012973.1 23206 25338 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7534278, 7559328, 16322107, 16173498, 15918181, 12454856, 7534278; Product type m : membrane component; outer membrane protein HopD complement(23206..25338) Helicobacter pylori B38 8207533 YP_003056866.1 CDS gltA NC_012973.1 25869 27149 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(25869..27149) Helicobacter pylori B38 8208651 YP_003056867.1 CDS icd NC_012973.1 27350 28627 D [NADP]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091606, 2204109, 2682654, 8759844; Product type e : enzyme; Isocitrate dehydrogenase 27350..28627 Helicobacter pylori B38 8208589 YP_003056868.1 CDS HELPY_0026 NC_012973.1 28694 29221 D Evidence 4b : Only in Helicobacter genus; hypothetical protein 28694..29221 Helicobacter pylori B38 8208706 YP_003056869.1 CDS bioD NC_012973.1 29198 29851 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 374977, 9214291, 7669755, 10089457, 99081548, 9865950; Product type e : enzyme; dethiobiotin synthetase complement(29198..29851) Helicobacter pylori B38 8207534 YP_003056870.1 CDS HELPY_0028 NC_012973.1 29855 31567 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(29855..31567) Helicobacter pylori B38 8208407 YP_003056871.1 CDS HELPY_0029 NC_012973.1 31676 32089 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16159758, 12732303; Product type pr : regulator; universal stress global response regulator UspA 31676..32089 Helicobacter pylori B38 8207535 YP_003056872.1 CDS clpS NC_012973.1 32104 32379 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11931773, 12426582; Product type r : regulator; ATP-dependent Clp protease adaptor protein ClpS 32104..32379 Helicobacter pylori B38 8207536 YP_003056873.1 CDS clpA NC_012973.1 32379 34604 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8885261, 3049606, 10555973, 10485712; Product type e : enzyme; ATP-dependent Clp protease ATP-binding subunit ClpA 32379..34604 Helicobacter pylori B38 8208428 YP_003056874.1 CDS panD NC_012973.1 34606 34947 D (Aspartate alpha-decarboxylase) [Contains: Aspartate 1-decarboxylase beta chain; Aspartate 1-decarboxylase alpha chain]; Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 34606..34947 Helicobacter pylori B38 8208425 YP_003056875.1 CDS HELPY_0033 NC_012973.1 34950 35252 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 34950..35252 Helicobacter pylori B38 8208838 YP_003056876.1 CDS HELPY_0034 NC_012973.1 35249 36256 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 35249..36256 Helicobacter pylori B38 8207537 YP_003056877.1 CDS HELPY_0035 NC_012973.1 36264 37319 D Evidence 4a : Only in Helicobacter pylori; Product type pm : membrane component; hypothetical protein 36264..37319 Helicobacter pylori B38 8207538 YP_003056878.1 CDS comB8 NC_012973.1 37445 38188 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12868652, 11489125, 11371528, 9663688; Product type t : transporter; DNA transformation competence protein ComB8 37445..38188 Helicobacter pylori B38 8207539 YP_003056879.1 CDS comB9 NC_012973.1 38188 39177 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12868652, 11489125, 11371528, 10920394, 9663688; Product type f : factor; DNA transformation competence protein ComB9 38188..39177 Helicobacter pylori B38 8208434 YP_003056880.1 CDS comB10 NC_012973.1 39170 40300 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12868652, 11489125, 11371528, 10920394, 9663688, 8763954; Product type f : factor; DNA transformation competence protein ComB10 39170..40300 Helicobacter pylori B38 8208435 YP_003056881.1 CDS manC NC_012973.1 40371 41783 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17547009, 16769546, 16713544, 15126474, 3089876; Product type e : enzyme; Alginate biosynthesis protein AlgA 40371..41783 Helicobacter pylori B38 8208432 YP_003056882.1 CDS gmd NC_012973.1 41824 42969 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14739333, 11856318, 11737200, 11444851, 9257704, 10673432, 8759852; Product type e : enzyme; GDP-mannose 4,6-dehydratase 41824..42969 Helicobacter pylori B38 8208749 YP_003056883.1 CDS fcl NC_012973.1 42962 43894 D : GDP-4-dehydro-6-deoxy-D-mannose epimerase; GDP-4-dehydro-6-L-deoxygalactose reductase; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9786182, 9473059, 9862812, 8759852; Product type e : enzyme; Bifunctional GDP-fucose synthetase 42962..43894 Helicobacter pylori B38 8208596 YP_003056884.1 CDS hypE NC_012973.1 44210 45208 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 16412426, 15291820, 1482271, 1849603; Product type f : factor; Hydrogenase expression/formation protein complement(44210..45208) Helicobacter pylori B38 8208500 YP_003056885.1 CDS hypF NC_012973.1 45220 47493 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 15491154, 11123699, 8661925; Product type r : regulator; Hydrogenase maturation protein HypF complement(45220..47493) Helicobacter pylori B38 8208704 YP_003056886.1 CDS HELPY_0044 NC_012973.1 47469 48461 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310, 10954588; Product type pe : enzyme; non-functional type II restriction endonuclease complement(47469..48461) Helicobacter pylori B38 8208705 YP_003056887.1 CDS hpy99VM NC_012973.1 48513 49211 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11226310, 10954588, 15297930, 12657791, 12486066, 12426350, 12355374; Product type e : enzyme; type II adenine methyltransferase complement(48513..49211) Helicobacter pylori B38 8207540 YP_003056888.1 CDS HELPY_0048 NC_012973.1 50353 51843 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16368996; Product type t : transporter; Symporter, SSS family (Proline Permease); membrane protein complement(50353..51843) Helicobacter pylori B38 8207542 YP_003056889.1 CDS putA NC_012973.1 51870 55427 R (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16452403, 15966737, 15449943, 7966312; Product type t : transporter; bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase complement(51870..55427) Helicobacter pylori B38 8207543 YP_003056890.1 CDS HELPY_0050 NC_012973.1 55756 55965 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 55756..55965 Helicobacter pylori B38 8208889 YP_003056891.1 CDS HELPY_0051 NC_012973.1 56288 57265 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 56288..57265 Helicobacter pylori B38 8207544 YP_003056892.1 CDS HELPY_0052 NC_012973.1 57266 58111 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 57266..58111 Helicobacter pylori B38 8207545 YP_003056893.1 CDS HELPY_0055 NC_012973.1 60534 61103 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 60534..61103 Helicobacter pylori B38 8207548 YP_003056894.1 CDS HELPY_0056 NC_012973.1 61119 61379 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 61119..61379 Helicobacter pylori B38 8207549 YP_003056895.1 CDS HELPY_0057 NC_012973.1 61390 63099 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 61390..63099 Helicobacter pylori B38 8207550 YP_003056896.1 CDS HELPY_0058 NC_012973.1 63132 63494 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 63132..63494 Helicobacter pylori B38 8207551 YP_003056897.1 CDS HELPY_0059 NC_012973.1 63496 63843 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 63496..63843 Helicobacter pylori B38 8207552 YP_003056898.1 CDS ureH NC_012973.1 66337 67134 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type f : factor; urease accessory protein UreH complement(66337..67134) Helicobacter pylori B38 8207556 YP_003056899.1 CDS ureG NC_012973.1 67134 67733 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type e : enzyme; urease accessory protein UreG complement(67134..67733) Helicobacter pylori B38 8209081 YP_003056900.1 CDS ureF NC_012973.1 67762 68532 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type e : enzyme; urease accessory protein UreF complement(67762..68532) Helicobacter pylori B38 8209080 YP_003056901.1 CDS ureE NC_012973.1 68556 69068 R involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE complement(68556..69068) Helicobacter pylori B38 8209079 YP_003056902.1 CDS ureI NC_012973.1 69070 69657 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16780553, 1313413, 10500143, 9209019, 7909161; Product type e : enzyme; urease accessory protein UreI complement(69070..69657) Helicobacter pylori B38 8209078 YP_003056903.1 CDS ureB NC_012973.1 69850 71559 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta complement(69850..71559) Helicobacter pylori B38 8209082 YP_003056904.1 CDS ureA NC_012973.1 71563 72279 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha complement(71563..72279) Helicobacter pylori B38 8209076 YP_003056905.1 CDS lspA NC_012973.1 72625 73098 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(72625..73098) Helicobacter pylori B38 8208348 YP_003056906.1 CDS glmM NC_012973.1 73092 74429 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(73092..74429) Helicobacter pylori B38 8208743 YP_003056907.1 CDS rpsT NC_012973.1 74519 74788 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 74519..74788 Helicobacter pylori B38 8209077 YP_003056908.1 CDS prfA NC_012973.1 74916 75974 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 74916..75974 Helicobacter pylori B38 8208994 YP_003056909.1 CDS HELPY_0077 NC_012973.1 78302 80065 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 78302..80065 Helicobacter pylori B38 8207558 YP_003056910.1 CDS tlpC NC_012973.1 80455 82476 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17517875, 16547053, 12228322, 96405614; Product type r : regulator; methyl-accepting chemotaxis protein complement(80455..82476) Helicobacter pylori B38 8207559 YP_003056911.1 CDS rpsI NC_012973.1 82617 83006 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(82617..83006) Helicobacter pylori B38 8209041 YP_003056912.1 CDS rplM NC_012973.1 83003 83428 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(83003..83428) Helicobacter pylori B38 8208983 YP_003056913.1 CDS HELPY_0082 NC_012973.1 83738 83926 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(83738..83926) Helicobacter pylori B38 8208949 YP_003056914.1 CDS mqo NC_012973.1 83932 85284 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10809701, 10809701, 16332763, 12480887; Product type e : enzyme; malate:quinone oxidoreductase complement(83932..85284) Helicobacter pylori B38 8207560 YP_003056915.1 CDS HELPY_0084 NC_012973.1 85338 86711 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(85338..86711) Helicobacter pylori B38 8208777 YP_003056916.1 CDS rpoD NC_012973.1 86732 88771 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(86732..88771) Helicobacter pylori B38 8207561 YP_003056917.1 CDS HELPY_0086 NC_012973.1 89051 89746 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(89051..89746) Helicobacter pylori B38 8208972 YP_003056918.1 CDS fabD NC_012973.1 89757 90686 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16699188, 16112872, 15952903, 14586097, 12842120, 12575934; Product type e : enzyme; Malonyl CoA-acyl carrier protein transacylase (MCT) complement(89757..90686) Helicobacter pylori B38 8207562 YP_003056919.1 CDS hpyAIIIM NC_012973.1 91938 92771 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12486066, 11226310; Product type e : enzyme; type II adenine methyltransferase 91938..92771 Helicobacter pylori B38 8207564 YP_003056920.1 CDS futC NC_012973.1 92792 93694 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16477004, 16720729; Product type e : enzyme; Alpha-1,2-fucosyltransferase complement(92792..93694) Helicobacter pylori B38 8208680 YP_003056921.1 CDS HELPY_0092 NC_012973.1 93794 94324 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(93794..94324) Helicobacter pylori B38 8208573 YP_003056922.1 CDS HELPY_0093 NC_012973.1 94397 95341 D Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 94397..95341 Helicobacter pylori B38 8207565 YP_003056923.1 CDS HELPY_0094 NC_012973.1 95555 96268 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(95555..96268) Helicobacter pylori B38 8207566 YP_003056924.1 CDS thrC NC_012973.1 96373 97827 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(96373..97827) Helicobacter pylori B38 8207567 YP_003056925.1 CDS HELPY_0097 NC_012973.1 98030 100057 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16529985, 16369945, 10692349; Product type pr : regulator; methyl-accepting chemotaxis protein 98030..100057 Helicobacter pylori B38 8209034 YP_003056926.1 CDS HELPY_0098 NC_012973.1 100057 101163 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 100057..101163 Helicobacter pylori B38 8207568 YP_003056927.1 CDS HELPY_0099 NC_012973.1 101376 102137 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein 101376..102137 Helicobacter pylori B38 8207569 YP_003056928.1 CDS HELPY_0100 NC_012973.1 102134 102901 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl transferase family protein complement(102134..102901) Helicobacter pylori B38 8207570 YP_003056929.1 CDS tlpB NC_012973.1 102933 104630 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15731083, 16547053; Product type m : membrane component; methyl-accepting chemotaxis protein tlpB complement(102933..104630) Helicobacter pylori B38 8207571 YP_003056930.1 CDS cpdB NC_012973.1 104833 106578 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11160814, 2172762, 6251162; Product type e : enzyme; 2,3-cyclic-nucleotide 2'phosphodiesterase complement(104833..106578) Helicobacter pylori B38 8209040 YP_003056931.1 CDS luxS NC_012973.1 106722 107180 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(106722..107180) Helicobacter pylori B38 8208441 YP_003056932.1 CDS metB NC_012973.1 107218 108360 R catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase complement(107218..108360) Helicobacter pylori B38 8208744 YP_003056933.1 CDS cysK NC_012973.1 108385 109302 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15952768, 14996787, 9034314; Product type e : enzyme; cysteine synthase complement(108385..109302) Helicobacter pylori B38 8208752 YP_003056934.1 CDS dnaK NC_012973.1 110242 112104 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(110242..112104) Helicobacter pylori B38 8207573 YP_003056935.1 CDS grpE NC_012973.1 112135 112710 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(112135..112710) Helicobacter pylori B38 8208468 YP_003056936.1 CDS hrcA NC_012973.1 112710 113480 R Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor complement(112710..113480) Helicobacter pylori B38 8208606 YP_003056937.1 CDS HELPY_0112 NC_012973.1 113752 114390 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511238, 15126455, 10821675, 8676381; Product type pe : enzyme; hypothetical protein 113752..114390 Helicobacter pylori B38 8208685 YP_003056938.1 CDS HELPY_0113 NC_012973.1 114411 114707 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 114411..114707 Helicobacter pylori B38 8207574 YP_003056939.1 CDS HELPY_0114 NC_012973.1 114717 116600 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(114717..116600) Helicobacter pylori B38 8207575 YP_003056940.1 CDS flaB NC_012973.1 116650 118194 R FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B complement(116650..118194) Helicobacter pylori B38 8207576 YP_003056941.1 CDS topA NC_012973.1 118360 120570 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 118360..120570 Helicobacter pylori B38 8208513 YP_003056942.1 CDS HELPY_0117 NC_012973.1 120563 121489 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 120563..121489 Helicobacter pylori B38 8209046 YP_003056943.1 CDS pps NC_012973.1 122932 125364 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(122932..125364) Helicobacter pylori B38 8207579 YP_003056944.1 CDS HELPY_0121 NC_012973.1 125549 125680 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 125549..125680 Helicobacter pylori B38 8208872 YP_003056945.1 CDS thrS NC_012973.1 125721 127559 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 125721..127559 Helicobacter pylori B38 8207580 YP_003056946.1 CDS infC NC_012973.1 127556 128167 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 127556..128167 Helicobacter pylori B38 8209035 YP_003056947.1 CDS rpmI NC_012973.1 128148 128342 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12166643; Product type s : structure; 50S ribosomal protein L35 128148..128342 Helicobacter pylori B38 8208714 YP_003056948.1 CDS rplT NC_012973.1 128436 128786 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 128436..128786 Helicobacter pylori B38 8208969 YP_003056949.1 CDS horB NC_012973.1 128986 129846 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10225855; Product type m : membrane component; outer membrane protein HorB 128986..129846 Helicobacter pylori B38 8208956 YP_003056950.1 CDS HELPY_0127 NC_012973.1 129889 130023 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 129889..130023 Helicobacter pylori B38 8208666 YP_003056951.1 CDS HELPY_0128 NC_012973.1 130196 130627 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 130196..130627 Helicobacter pylori B38 8207581 YP_003056952.1 CDS HELPY_0130 NC_012973.1 131040 131900 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 131040..131900 Helicobacter pylori B38 8207582 YP_003056953.1 CDS sdaA NC_012973.1 132534 133901 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2013569, 2504697; Product type e : enzyme; L-serine dehydratase complement(132534..133901) Helicobacter pylori B38 8207583 YP_003056954.1 CDS sdaC NC_012973.1 133901 135142 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16285745, 15629915, 15743941, 12558182, 8026499; Product type t : transporter; Aminoacid transport protein, HAAAP family; membrane protein complement(133901..135142) Helicobacter pylori B38 8209001 YP_003056955.1 CDS aroF NC_012973.1 135323 136672 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8760910, 11506923; Product type e : enzyme; Tyrosine-regulated 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHP synthase) 135323..136672 Helicobacter pylori B38 8209002 YP_003056956.1 CDS HELPY_0136 NC_012973.1 136961 137095 D Evidence 4b : Only in Helicobacter genus; hypothetical protein 136961..137095 Helicobacter pylori B38 8208384 YP_003056957.1 CDS bcp NC_012973.1 137327 137785 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15618175, 10998352, 10644761; Product type e : enzyme; Bacterioferritin comigratory protein complement(137327..137785) Helicobacter pylori B38 8207584 YP_003056958.1 CDS HELPY_0138 NC_012973.1 137795 138430 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(137795..138430) Helicobacter pylori B38 8208403 YP_003056959.1 CDS HELPY_0139 NC_012973.1 138423 139868 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; iron-sulfur cluster binding protein complement(138423..139868) Helicobacter pylori B38 8207585 YP_003056960.1 CDS HELPY_0140 NC_012973.1 139897 140625 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(139897..140625) Helicobacter pylori B38 8207586 YP_003056961.1 CDS HELPY_0142 NC_012973.1 140850 142499 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8407843, 11785976; Product type t : transporter; L-lactate permease, LctP family; membrane protein 140850..142499 Helicobacter pylori B38 8207587 YP_003056962.1 CDS HELPY_0143 NC_012973.1 142549 144204 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8407843, 11785976; Product type t : transporter; L-lactate permease, LctP family; membrane protein 142549..144204 Helicobacter pylori B38 8207588 YP_003056963.1 CDS mutY NC_012973.1 144228 145100 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10320570, 16720376, 16201966, 15805527; Product type e : enzyme; DNA glycosylase MutY complement(144228..145100) Helicobacter pylori B38 8207589 YP_003056964.1 CDS HELPY_0145 NC_012973.1 145215 146663 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9696764; Product type t : transporter; sodium/sulfate symporter complement(145215..146663) Helicobacter pylori B38 8208792 YP_003056965.1 CDS fixN NC_012973.1 146833 148299 D CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 146833..148299 Helicobacter pylori B38 8207590 YP_003056966.1 CDS fixO NC_012973.1 148312 149010 D CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 148312..149010 Helicobacter pylori B38 8208507 YP_003056967.1 CDS fixQ NC_012973.1 149018 149239 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14714103, 10985736, 9880817, 8757739, 14714103, 10736149, 9880817; Product type e : enzyme; Cytochrome c oxidase subunit Q 149018..149239 Helicobacter pylori B38 8208508 YP_003056968.1 CDS fixP NC_012973.1 149241 150119 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14714103, 10985736, 9880817, 8757739, 14714103, 10736149, 9880817; Product type e : enzyme; Cytochrome c oxidase diheme subunit 149241..150119 Helicobacter pylori B38 8208510 YP_003056969.1 CDS HELPY_0152 NC_012973.1 150130 150336 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 150130..150336 Helicobacter pylori B38 8208509 YP_003056970.1 CDS HELPY_0153 NC_012973.1 150437 151021 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 150437..151021 Helicobacter pylori B38 8207591 YP_003056971.1 CDS HELPY_0154 NC_012973.1 151034 151615 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 151034..151615 Helicobacter pylori B38 8207592 YP_003056972.1 CDS HELPY_0155 NC_012973.1 151704 152471 D Evidence 4a : Only in Helicobacter pylori; Product type m : membrane component; hypothetical protein 151704..152471 Helicobacter pylori B38 8207593 YP_003056973.1 CDS HELPY_0156 NC_012973.1 152468 153331 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(152468..153331) Helicobacter pylori B38 8207594 YP_003056974.1 CDS recA NC_012973.1 153431 154474 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 153431..154474 Helicobacter pylori B38 8207595 YP_003056975.1 CDS eno NC_012973.1 154484 155767 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 154484..155767 Helicobacter pylori B38 8208905 YP_003056976.1 CDS HELPY_0159 NC_012973.1 155760 156035 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 155760..156035 Helicobacter pylori B38 8208485 YP_003056977.1 CDS HELPY_0160 NC_012973.1 156046 156648 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 156046..156648 Helicobacter pylori B38 8207596 YP_003056978.1 CDS aroK NC_012973.1 156653 157141 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 156653..157141 Helicobacter pylori B38 8207597 YP_003056979.1 CDS HELPY_0162 NC_012973.1 157163 158119 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 157163..158119 Helicobacter pylori B38 8208385 YP_003056980.1 CDS rfaJ1 NC_012973.1 158116 159219 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15814825, 15556710, 9780260, 1624462, 1624461; Product type e : enzyme; LPS 1,2-glycosyltransferase complement(158116..159219) Helicobacter pylori B38 8207598 YP_003056981.1 CDS hcpD NC_012973.1 159373 160293 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10438788, 11777911, 10748053; Product type e : enzyme; cysteinyl-tRNA synthetase 159373..160293 Helicobacter pylori B38 8208914 YP_003056982.1 CDS HELPY_0165 NC_012973.1 160817 161539 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(160817..161539) Helicobacter pylori B38 8208616 YP_003056983.1 CDS hemB NC_012973.1 161540 162499 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(161540..162499) Helicobacter pylori B38 8207599 YP_003056984.1 CDS HELPY_0168 NC_012973.1 162533 163864 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16484186, 15109719, 10722597, 10418137; Product type r : regulator; Histidine kinase sensor protein complement(162533..163864) Helicobacter pylori B38 8208625 YP_003056985.1 CDS ompR NC_012973.1 163890 164567 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16769709, 16672598, 16484186, 1674092, 16618701, 16553882, 16539733; Product type r : regulator; transcriptional regulator complement(163890..164567) Helicobacter pylori B38 8207600 YP_003056986.1 CDS HELPY_0170 NC_012973.1 164810 165277 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(164810..165277) Helicobacter pylori B38 8208828 YP_003056987.1 CDS HELPY_0171 NC_012973.1 165268 165531 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(165268..165531) Helicobacter pylori B38 8207601 YP_003056988.1 CDS HELPY_0172 NC_012973.1 165565 166845 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protease complement(165565..166845) Helicobacter pylori B38 8207602 YP_003056989.1 CDS HELPY_0173 NC_012973.1 166848 167579 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(166848..167579) Helicobacter pylori B38 8207603 YP_003056990.1 CDS prfB NC_012973.1 167649 168740 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(167649..168740) Helicobacter pylori B38 8207604 YP_003056991.1 CDS moeA NC_012973.1 168801 169976 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11934270, 12382055, 12420167, 12006571, 9515915, 9851041, 9388540; Product type f : factor; molybdopterin biosynthesis protein MoeA complement(168801..169976) Helicobacter pylori B38 8208874 YP_003056992.1 CDS fliR NC_012973.1 169986 170753 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(169986..170753) Helicobacter pylori B38 8208772 YP_003056993.1 CDS HELPY_0177 NC_012973.1 170747 171475 R Evidence 4b : Only in Helicobacter genus; Product type pm : membrane component; hypothetical protein complement(170747..171475) Helicobacter pylori B38 8208544 YP_003056994.1 CDS ppiC NC_012973.1 171948 172847 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2186809, 7878731, 7925971, 9546151; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase C 171948..172847 Helicobacter pylori B38 8207605 YP_003056995.1 CDS fba NC_012973.1 172864 173787 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 172864..173787 Helicobacter pylori B38 8208869 YP_003056996.1 CDS efp NC_012973.1 173809 174372 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 173809..174372 Helicobacter pylori B38 8208498 YP_003056997.1 CDS neuB NC_012973.1 174875 175903 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10873658, 10712693; Product type e : enzyme; sialic acid synthase complement(174875..175903) Helicobacter pylori B38 8208483 YP_003056998.1 CDS HELPY_0183 NC_012973.1 175907 176548 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16400872, 16092522, 15749056, 1531323, 10518715, 9593292; Product type t : transporter; ABC transporter ATP-binding protein complement(175907..176548) Helicobacter pylori B38 8208798 YP_003056999.1 CDS lnt NC_012973.1 176545 177822 R transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(176545..177822) Helicobacter pylori B38 8207606 YP_003057000.1 CDS HELPY_0185 NC_012973.1 178053 178754 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 178053..178754 Helicobacter pylori B38 8208732 YP_003057001.1 CDS lysS NC_012973.1 178764 180269 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 178764..180269 Helicobacter pylori B38 8207607 YP_003057002.1 CDS glyA NC_012973.1 180269 181519 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 180269..181519 Helicobacter pylori B38 8208747 YP_003057003.1 CDS HELPY_0188 NC_012973.1 181530 182072 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 181530..182072 Helicobacter pylori B38 8208593 YP_003057004.1 CDS HELPY_0189 NC_012973.1 182094 182897 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 182094..182897 Helicobacter pylori B38 8207608 YP_003057005.1 CDS HELPY_0192 NC_012973.1 185156 185689 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 185156..185689 Helicobacter pylori B38 8207611 YP_003057006.1 CDS HELPY_0193 NC_012973.1 185695 187203 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phospholipase D complement(185695..187203) Helicobacter pylori B38 8207612 YP_003057007.1 CDS frdB NC_012973.1 187225 187962 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(187225..187962) Helicobacter pylori B38 8207613 YP_003057008.1 CDS frdA NC_012973.1 187955 190099 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(187955..190099) Helicobacter pylori B38 8208555 YP_003057009.1 CDS frdC NC_012973.1 190109 190876 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit complement(190109..190876) Helicobacter pylori B38 8208554 YP_003057010.1 CDS tpiA NC_012973.1 191092 191796 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 191092..191796 Helicobacter pylori B38 8208556 YP_003057011.1 CDS HELPY_0198 NC_012973.1 191806 192633 D [NADH]; Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 191806..192633 Helicobacter pylori B38 8209047 YP_003057012.1 CDS lpxD NC_012973.1 192643 193653 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 192643..193653 Helicobacter pylori B38 8207614 YP_003057013.1 CDS metK NC_012973.1 193718 194875 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 193718..194875 Helicobacter pylori B38 8208741 YP_003057014.1 CDS ndk NC_012973.1 194942 195355 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 194942..195355 Helicobacter pylori B38 8208753 YP_003057015.1 CDS HELPY_0202 NC_012973.1 195381 195737 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 195381..195737 Helicobacter pylori B38 8208797 YP_003057016.1 CDS rpmF NC_012973.1 195753 195899 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 195753..195899 Helicobacter pylori B38 8207615 YP_003057017.1 CDS plsX NC_012973.1 195963 196985 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 195963..196985 Helicobacter pylori B38 8208965 YP_003057018.1 CDS fabH NC_012973.1 197010 198002 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 197010..198002 Helicobacter pylori B38 8208860 YP_003057019.1 CDS HELPY_0206 NC_012973.1 198023 198325 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 198023..198325 Helicobacter pylori B38 8208496 YP_003057020.1 CDS HELPY_0207 NC_012973.1 198951 199334 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(198951..199334) Helicobacter pylori B38 8207616 YP_003057021.1 CDS mrp NC_012973.1 202476 203582 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9600981; Product type e : enzyme; ATP-binding protein 202476..203582 Helicobacter pylori B38 8207619 YP_003057022.1 CDS rfaJ2 NC_012973.1 203596 204768 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15814825, 15556710, 9780260, 1624462, 1624461; Product type e : enzyme; LPS 1,2-glycosyltransferase complement(203596..204768) Helicobacter pylori B38 8208781 YP_003057023.1 CDS hofA NC_012973.1 204927 206279 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type pm : membrane component; outer membrane protein HofA 204927..206279 Helicobacter pylori B38 8208915 YP_003057024.1 CDS htpG NC_012973.1 206382 208247 D molecular chaperone; heat shock protein 90 206382..208247 Helicobacter pylori B38 8208636 YP_003057025.1 CDS hcpA NC_012973.1 208444 209196 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10748053, 11777911, 9317022, 9596777; Product type e : enzyme; Cysteine-rich protein A complement(208444..209196) Helicobacter pylori B38 8208693 YP_003057026.1 CDS dapE NC_012973.1 209655 210806 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(209655..210806) Helicobacter pylori B38 8208614 YP_003057027.1 CDS gidA NC_012973.1 210817 212682 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(210817..212682) Helicobacter pylori B38 8208451 YP_003057028.1 CDS HELPY_0217 NC_012973.1 212778 214436 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; symtransporter; membrane protein 212778..214436 Helicobacter pylori B38 8208582 YP_003057029.1 CDS cdsA NC_012973.1 214449 215249 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2995359; Product type e : enzyme; phosphatidate cytidylyltransferase 214449..215249 Helicobacter pylori B38 8207620 YP_003057030.1 CDS dxr NC_012973.1 215250 216356 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 215250..216356 Helicobacter pylori B38 8208417 YP_003057031.1 CDS HELPY_0222 NC_012973.1 217563 218114 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11439028; hypothetical protein complement(217563..218114) Helicobacter pylori B38 8207622 YP_003057032.1 CDS HELPY_0223 NC_012973.1 218259 218720 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 218259..218720 Helicobacter pylori B38 8207623 YP_003057033.1 CDS nifS NC_012973.1 218891 220054 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11123951, 16185064, 15952888, 15667274, 1219616, 8482384; Product type e : enzyme; cysteine desulfurase 218891..220054 Helicobacter pylori B38 8207624 YP_003057034.1 CDS nifU NC_012973.1 220076 221056 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11123951, 16185064, 15952888, 15667274, 1219616, 8482384; Product type f : factor; [Fe-S] cluster scaffold protein 220076..221056 Helicobacter pylori B38 8208800 YP_003057035.1 CDS radA NC_012973.1 221557 222903 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 221557..222903 Helicobacter pylori B38 8207626 YP_003057036.1 CDS msr NC_012973.1 223017 224096 D [peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (peptide Met(O) reductase); peptide methionine sulfoxide reductase MsrB]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15387818, 7836279, 7017726, 1386361, 8755589, 9596777; Product type e : enzyme; peptide methionine sulfoxide reductase 223017..224096 Helicobacter pylori B38 8208901 YP_003057037.1 CDS HELPY_0230 NC_012973.1 224528 225361 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(224528..225361) Helicobacter pylori B38 8208782 YP_003057038.1 CDS hopM NC_012973.1 225574 227664 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopM complement(225574..227664) Helicobacter pylori B38 8207627 YP_003057039.1 CDS HELPY_0232 NC_012973.1 227919 229076 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7616962; Product type pt : transporter; sulfate permease 227919..229076 Helicobacter pylori B38 8208661 YP_003057040.1 CDS hopA NC_012973.1 229311 230762 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7534278, 7559328, 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopA complement(229311..230762) Helicobacter pylori B38 8208347 YP_003057041.1 CDS kdsB NC_012973.1 230956 231687 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(230956..231687) Helicobacter pylori B38 8208648 YP_003057042.1 CDS HELPY_0235 NC_012973.1 231794 232591 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 231794..232591 Helicobacter pylori B38 8208723 YP_003057043.1 CDS HELPY_0236 NC_012973.1 232607 233257 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 8733234; Product type pf : factor; hypothetical protein 232607..233257 Helicobacter pylori B38 8207629 YP_003057044.1 CDS gsp NC_012973.1 233281 234453 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7775463; Product type e : enzyme; glutathionylspermidine synthase 233281..234453 Helicobacter pylori B38 8207630 YP_003057045.1 CDS HELPY_0239 NC_012973.1 234453 234983 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 234453..234983 Helicobacter pylori B38 8208607 YP_003057046.1 CDS hcpE NC_012973.1 235702 236769 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10438788, 10748053, 11777911, 12853383; Product type pe : enzyme; Cysteine-rich protein E; beta-lactamase HcpE complement(235702..236769) Helicobacter pylori B38 8207631 YP_003057047.1 CDS HELPY_0241 NC_012973.1 236863 237234 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(236863..237234) Helicobacter pylori B38 8208617 YP_003057048.1 CDS hemC NC_012973.1 237234 238154 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(237234..238154) Helicobacter pylori B38 8207632 YP_003057049.1 CDS proS NC_012973.1 238165 239898 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(238165..239898) Helicobacter pylori B38 8208626 YP_003057050.1 CDS hemA NC_012973.1 239902 241251 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(239902..241251) Helicobacter pylori B38 8208878 YP_003057051.1 CDS ispB NC_012973.1 241251 242174 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16257556, 11108713, 9139929, 8037730; Product type e : enzyme; Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase) complement(241251..242174) Helicobacter pylori B38 8208624 YP_003057052.1 CDS HELPY_0246 NC_012973.1 242184 242579 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(242184..242579) Helicobacter pylori B38 8208716 YP_003057053.1 CDS HELPY_0247 NC_012973.1 242572 242856 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(242572..242856) Helicobacter pylori B38 8207633 YP_003057054.1 CDS napA NC_012973.1 242877 243311 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10790419, 10564468, 16298743, 16041003, 15788154, 15637768, 12748264; Product type ph : phenotype; Neutrophil activating protein NapA (bacterioferritin) complement(242877..243311) Helicobacter pylori B38 8207634 YP_003057055.1 CDS HELPY_0249 NC_012973.1 243517 244662 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8346225; Product type r : regulator; signal-transducing protein AtoS, histidine kinase complement(243517..244662) Helicobacter pylori B38 8208796 YP_003057056.1 CDS HELPY_0250 NC_012973.1 244659 244976 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(244659..244976) Helicobacter pylori B38 8207635 YP_003057057.1 CDS flgI NC_012973.1 244973 246001 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(244973..246001) Helicobacter pylori B38 8207636 YP_003057058.1 CDS deaD NC_012973.1 246190 247668 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1552844, 16352840, 16337753; Product type e : enzyme; ATP-dependent RNA helicase, DEAD-box family DEAD 246190..247668 Helicobacter pylori B38 8208524 YP_003057059.1 CDS HELPY_0253 NC_012973.1 247689 248777 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 247689..248777 Helicobacter pylori B38 8208456 YP_003057060.1 CDS HELPY_0254 NC_012973.1 248784 249323 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 248784..249323 Helicobacter pylori B38 8207637 YP_003057061.1 CDS HELPY_0255 NC_012973.1 249374 250924 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter ATP-binding protein complement(249374..250924) Helicobacter pylori B38 8207638 YP_003057062.1 CDS hopF NC_012973.1 252293 253750 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10454640; Product type m : membrane component; outer membrane protein HopF 252293..253750 Helicobacter pylori B38 8208345 YP_003057063.1 CDS hopG NC_012973.1 253763 255175 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10454640; Product type m : membrane component; outer membrane protein HopG 253763..255175 Helicobacter pylori B38 8208653 YP_003057064.1 CDS purA NC_012973.1 255274 256509 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 255274..256509 Helicobacter pylori B38 8208654 YP_003057065.1 CDS HELPY_0261 NC_012973.1 256506 256934 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 256506..256934 Helicobacter pylori B38 8208885 YP_003057066.1 CDS HELPY_0262 NC_012973.1 256927 257598 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 256927..257598 Helicobacter pylori B38 8207642 YP_003057067.1 CDS HELPY_0263 NC_012973.1 257598 258644 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase M50 (membrane-associated zinc metallopeptidase), MEROPS family; membrane protein 257598..258644 Helicobacter pylori B38 8207643 YP_003057068.1 CDS xseA NC_012973.1 258657 259919 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 258657..259919 Helicobacter pylori B38 8207644 YP_003057069.1 CDS HELPY_0265 NC_012973.1 259939 261111 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11133936, 10954588; Product type e : enzyme; TCGA site-specific m6A methyltransferase complement(259939..261111) Helicobacter pylori B38 8209093 YP_003057070.1 CDS HELPY_0266 NC_012973.1 261104 261346 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(261104..261346) Helicobacter pylori B38 8207645 YP_003057071.1 CDS hpy99VIIIM NC_012973.1 262117 262875 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11226310, 10944229, 10954588; Product type e : enzyme; Non-functional cytosine methyltransferase 262117..262875 Helicobacter pylori B38 8207648 YP_003057072.1 CDS clpB NC_012973.1 262948 265518 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1906060, 8885261, 2185473, 9651675, 16289019; Product type f : factor; ATP-dependent protease binding subunit/heat shock protein 262948..265518 Helicobacter pylori B38 8208677 YP_003057073.1 CDS ccdA NC_012973.1 265572 266294 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16109941, 15159384; Product type m : membrane component; Cytochrome C biogenesis protein; membrane protein 265572..266294 Helicobacter pylori B38 8208426 YP_003057074.1 CDS pyrC NC_012973.1 266304 267437 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16522191, 15278241, 858905, 16255137, 10938275, 7928775; Product type e : enzyme; Dihydroorotase (DHOase) 266304..267437 Helicobacter pylori B38 8208414 YP_003057075.1 CDS HELPY_0273 NC_012973.1 267425 268651 D Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 267425..268651 Helicobacter pylori B38 8208892 YP_003057076.1 CDS HELPY_0274 NC_012973.1 268711 268953 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 268711..268953 Helicobacter pylori B38 8207649 YP_003057077.1 CDS HELPY_0275 NC_012973.1 268963 270276 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 268963..270276 Helicobacter pylori B38 8207650 YP_003057078.1 CDS HELPY_0276 NC_012973.1 270316 270969 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 270316..270969 Helicobacter pylori B38 8207651 YP_003057079.1 CDS HELPY_0277 NC_012973.1 270962 271942 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 270962..271942 Helicobacter pylori B38 8207652 YP_003057080.1 CDS HELPY_0278 NC_012973.1 271932 272465 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 271932..272465 Helicobacter pylori B38 8207653 YP_003057081.1 CDS HELPY_0279 NC_012973.1 272462 273001 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 272462..273001 Helicobacter pylori B38 8207654 YP_003057082.1 CDS HELPY_0280 NC_012973.1 273018 273416 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 273018..273416 Helicobacter pylori B38 8207655 YP_003057083.1 CDS HELPY_0281 NC_012973.1 273453 274748 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 273453..274748 Helicobacter pylori B38 8207656 YP_003057084.1 CDS HELPY_0282 NC_012973.1 274793 275293 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 274793..275293 Helicobacter pylori B38 8207657 YP_003057085.1 CDS HELPY_0283 NC_012973.1 275350 275604 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15866207, 12700272, 10898687; Product type pc : carrier; 4Fe-4S ferredoxin 275350..275604 Helicobacter pylori B38 8207658 YP_003057086.1 CDS gppA NC_012973.1 275614 277068 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2005135, 9882669, 15248747, 8394006; Product type e : enzyme; guanosine pentaphosphate phosphohydrolase 275614..277068 Helicobacter pylori B38 8207659 YP_003057087.1 CDS waaC NC_012973.1 277065 278075 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8478319, 9446588, 16109967, 12591937, 11717579, 11054112; Product type e : enzyme; Lipopolysaccharide heptosyltransferase 1 277065..278075 Helicobacter pylori B38 8208601 YP_003057088.1 CDS waaM NC_012973.1 278072 279058 D acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 278072..279058 Helicobacter pylori B38 8209090 YP_003057089.1 CDS tgt NC_012973.1 279129 280244 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(279129..280244) Helicobacter pylori B38 8209091 YP_003057090.1 CDS HELPY_0288 NC_012973.1 280295 281737 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 280295..281737 Helicobacter pylori B38 8209028 YP_003057091.1 CDS aroB NC_012973.1 281742 282773 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 281742..282773 Helicobacter pylori B38 8207660 YP_003057092.1 CDS HELPY_0290 NC_012973.1 282764 284335 D Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 282764..284335 Helicobacter pylori B38 8208381 YP_003057093.1 CDS HELPY_0291 NC_012973.1 284332 285588 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11882645, 15339930; Product type pe : enzyme; MiaB-like tRNA modifying enzyme 284332..285588 Helicobacter pylori B38 8207661 YP_003057094.1 CDS ftsH1 NC_012973.1 285575 287227 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 18421140, 8892813, 9244252, 8550601, 9560419; Product type e : enzyme; Cell division protein FtsH 285575..287227 Helicobacter pylori B38 8207662 YP_003057095.1 CDS HELPY_0293 NC_012973.1 287230 287748 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 287230..287748 Helicobacter pylori B38 8208563 YP_003057096.1 CDS HELPY_0294 NC_012973.1 287761 288234 D Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 287761..288234 Helicobacter pylori B38 8207663 YP_003057097.1 CDS HELPY_0295 NC_012973.1 288302 297028 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16610017, 16579839, 16579837, 16552038, 16497614, 16489309; Product type pm : membrane component; toxin-like outer membrane protein/vacuolating cytotoxin VacA 288302..297028 Helicobacter pylori B38 8207664 YP_003057098.1 CDS lysA NC_012973.1 297076 298293 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511157, 14633099, 12355264; Product type e : enzyme; Diaminopimelate decarboxylas (DAP decarboxylase) 297076..298293 Helicobacter pylori B38 8207665 YP_003057099.1 CDS HELPY_0297 NC_012973.1 298298 298588 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3, 2, 7496998, 8000535, 15753077, 15534933; Product type pe : enzyme; chorismate mutase PheA 298298..298588 Helicobacter pylori B38 8208745 YP_003057100.1 CDS HELPY_0298 NC_012973.1 298601 299473 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 298601..299473 Helicobacter pylori B38 8207666 YP_003057101.1 CDS pabB NC_012973.1 299474 301153 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11450855, 11371633, 8679677, 14745019, 8472953, 2656685, 3057324; Product type e : enzyme; Para-aminobenzoate (PABA)-synthetase 299474..301153 Helicobacter pylori B38 8207667 YP_003057102.1 CDS amiE NC_012973.1 301348 302367 D aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 301348..302367 Helicobacter pylori B38 8208833 YP_003057103.1 CDS flgL NC_012973.1 302449 304935 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL complement(302449..304935) Helicobacter pylori B38 8208375 YP_003057104.1 CDS rplU NC_012973.1 305177 305491 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type s : structure; 50S ribosomal protein L21 305177..305491 Helicobacter pylori B38 8208526 YP_003057105.1 CDS rpmA NC_012973.1 305506 305772 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 305506..305772 Helicobacter pylori B38 8208957 YP_003057106.1 CDS dppA NC_012973.1 305889 307538 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 8527431, 1956284, 15845494, 14568145; Product type t : transporter; peptide ABC transporter substrate-binding protein 305889..307538 Helicobacter pylori B38 8208962 YP_003057107.1 CDS dppB NC_012973.1 307549 308553 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 14568145, 11858173, 7536291; Product type t : transporter; ABC transporter permease; dipeptide transporter protein 2; membrane protein 307549..308553 Helicobacter pylori B38 8208472 YP_003057108.1 CDS dppC NC_012973.1 308553 309410 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 11858173, 9680220; Product type t : transporter; ABC transporter permease; dipeptide transporter protein 3; membrane protein 308553..309410 Helicobacter pylori B38 8208473 YP_003057109.1 CDS dppD NC_012973.1 309422 310285 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 11858173, 9680220; Product type t : transporter; ABC transporter ATP-binding protein; dipeptide transporter protein 4 309422..310285 Helicobacter pylori B38 8208474 YP_003057110.1 CDS dppF NC_012973.1 310282 311088 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16181352, 11858173, 9680220, 7536291; Product type t : transporter; ABC transporter ATP-binding protein; dipeptide transporter protein 5 310282..311088 Helicobacter pylori B38 8208475 YP_003057111.1 CDS obgE NC_012973.1 311107 312189 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 311107..312189 Helicobacter pylori B38 8208476 YP_003057112.1 CDS HELPY_0311 NC_012973.1 312231 313226 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 312231..313226 Helicobacter pylori B38 8207668 YP_003057113.1 CDS HELPY_0312 NC_012973.1 313492 314046 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 313492..314046 Helicobacter pylori B38 8207669 YP_003057114.1 CDS hemL NC_012973.1 314056 315348 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 314056..315348 Helicobacter pylori B38 8207670 YP_003057115.1 CDS HELPY_0314 NC_012973.1 315345 315617 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 315345..315617 Helicobacter pylori B38 8208631 YP_003057116.1 CDS HELPY_0315 NC_012973.1 315633 316037 D Evidence 4b : Only in Helicobacter genus; Product type pm : membrane component; hypothetical protein 315633..316037 Helicobacter pylori B38 8207671 YP_003057117.1 CDS HELPY_0316 NC_012973.1 316121 316999 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7987228, 11380987, 12054553; Product type pe : enzyme; N-carbomoyl-D-amino acid amidohydrolase 316121..316999 Helicobacter pylori B38 8207672 YP_003057118.1 CDS HELPY_0317 NC_012973.1 317012 317893 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9163424, 8170399, 9163415; Product type pe : enzyme; NodB-like polysaccharide deacetylase 317012..317893 Helicobacter pylori B38 8207673 YP_003057119.1 CDS HELPY_0318 NC_012973.1 317939 318316 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 317939..318316 Helicobacter pylori B38 8207674 YP_003057120.1 CDS HELPY_0319 NC_012973.1 318316 319278 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1655697, 1624427, 8423137, 9209019, 9140970; Product type pf : factor; cobalamin syntheis protein, P47K family; ATP/GTP binding protein 318316..319278 Helicobacter pylori B38 8207675 YP_003057121.1 CDS HELPY_0320 NC_012973.1 319284 320426 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17347820; Product type pt : transporter; nitrite extrusion protein, major facilitator family protein; membrane protein complement(319284..320426) Helicobacter pylori B38 8207676 YP_003057122.1 CDS HELPY_0321 NC_012973.1 320936 321694 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(320936..321694) Helicobacter pylori B38 8207677 YP_003057123.1 CDS argS NC_012973.1 321805 323430 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(321805..323430) Helicobacter pylori B38 8207678 YP_003057124.1 CDS tatA NC_012973.1 323433 323672 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16291683, 16027357, 12867413, 11591389, 11422364, 11350936; Product type t : transporter; Sec-independent protein translocase protein tatA/E-like protein complement(323433..323672) Helicobacter pylori B38 8208379 YP_003057125.1 CDS gmk NC_012973.1 323744 324364 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(323744..324364) Helicobacter pylori B38 8209025 YP_003057126.1 CDS HELPY_0325 NC_012973.1 324357 325700 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(324357..325700) Helicobacter pylori B38 8208599 YP_003057127.1 CDS HELPY_0326 NC_012973.1 325844 326386 D membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT 325844..326386 Helicobacter pylori B38 8207679 YP_003057128.1 CDS horC NC_012973.1 326396 327133 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HorC complement(326396..327133) Helicobacter pylori B38 8207680 YP_003057129.1 CDS flgH NC_012973.1 327274 327987 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 327274..327987 Helicobacter pylori B38 8208667 YP_003057130.1 CDS HELPY_0331 NC_012973.1 329554 330096 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2921244, 9748431, 15687208, 15361076, 10559162; Product type ps : structure; flagellar biosynthesis protein 329554..330096 Helicobacter pylori B38 8207682 YP_003057131.1 CDS lpxK NC_012973.1 330029 330967 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(330029..330967) Helicobacter pylori B38 8207683 YP_003057132.1 CDS nadE NC_012973.1 330964 331746 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(330964..331746) Helicobacter pylori B38 8208742 YP_003057133.1 CDS ilvC NC_012973.1 331998 332990 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 331998..332990 Helicobacter pylori B38 8208335 YP_003057134.1 CDS minD NC_012973.1 333014 333820 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16585760, 16584194, 2645057, 10220403, 1836760, 11566131, 16376524; Product type e : enzyme; Cell division inhibitor MinD 333014..333820 Helicobacter pylori B38 8208709 YP_003057135.1 CDS minE NC_012973.1 333817 334050 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 333817..334050 Helicobacter pylori B38 8208759 YP_003057136.1 CDS dprA NC_012973.1 334057 334857 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10482496, 10640603, 16194595, 14617176, 12123453, 11823215; Product type f : factor; DNA processing chain A (DprA) 334057..334857 Helicobacter pylori B38 8208760 YP_003057137.1 CDS HELPY_0338 NC_012973.1 334854 335258 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 334854..335258 Helicobacter pylori B38 8208477 YP_003057138.1 CDS hcpH NC_012973.1 335452 336045 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9596777, 11777911, 12853383, 15223324; Product type e : enzyme; hypothetical protein 335452..336045 Helicobacter pylori B38 8207684 YP_003057139.1 CDS HELPY_0340 NC_012973.1 336231 336569 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 336231..336569 Helicobacter pylori B38 8208619 YP_003057140.1 CDS HELPY_0341 NC_012973.1 336553 337113 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 336553..337113 Helicobacter pylori B38 8207685 YP_003057141.1 CDS HELPY_0345 NC_012973.1 338106 338492 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 338106..338492 Helicobacter pylori B38 8207689 YP_003057142.1 CDS HELPY_0346 NC_012973.1 338492 339277 D Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 338492..339277 Helicobacter pylori B38 8207690 YP_003057143.1 CDS rluD NC_012973.1 340457 341353 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9660827, 16511038, 15928344; Product type e : enzyme; Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) complement(340457..341353) Helicobacter pylori B38 8207694 YP_003057144.1 CDS recJ NC_012973.1 341353 342903 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2649886, 16488881, 15687199, 10498723; Product type e : enzyme; ssDNA-specific exonuclease RecJ complement(341353..342903) Helicobacter pylori B38 8208926 YP_003057145.1 CDS pyrG NC_012973.1 342912 344528 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(342912..344528) Helicobacter pylori B38 8208907 YP_003057146.1 CDS HELPY_0353 NC_012973.1 344783 345451 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 344783..345451 Helicobacter pylori B38 8208897 YP_003057147.1 CDS fliF NC_012973.1 345495 347198 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 345495..347198 Helicobacter pylori B38 8207695 YP_003057148.1 CDS fliG NC_012973.1 347211 348242 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 347211..348242 Helicobacter pylori B38 8208535 YP_003057149.1 CDS fliH NC_012973.1 348235 349008 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 348235..349008 Helicobacter pylori B38 8208536 YP_003057150.1 CDS dxs NC_012973.1 349005 350861 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 349005..350861 Helicobacter pylori B38 8208537 YP_003057151.1 CDS lepA NC_012973.1 350858 352666 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 350858..352666 Helicobacter pylori B38 8208480 YP_003057152.1 CDS HELPY_0359 NC_012973.1 352681 353436 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 352681..353436 Helicobacter pylori B38 8208727 YP_003057153.1 CDS HELPY_0360 NC_012973.1 353439 353675 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 353439..353675 Helicobacter pylori B38 8207696 YP_003057154.1 CDS flgG NC_012973.1 354248 355057 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9931471, 15136044, 1503936; Product type s : structure; Flagellar basal-body rod protein FlgG (Distal rod protein) complement(354248..355057) Helicobacter pylori B38 8207697 YP_003057155.1 CDS HELPY_0362 NC_012973.1 355111 356397 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1556144, 10613883, 2053984; Product type t : transporter; MFS superfamily alpha-ketoglutarate permease complement(355111..356397) Helicobacter pylori B38 8208521 YP_003057156.1 CDS ftsK NC_012973.1 356560 359127 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16612541, 16553881, 16452433, 16301526, 16194242, 15491352, 9748467; Product type ph : phenotype; DNA translocase FtsK; membrane protein complement(356560..359127) Helicobacter pylori B38 8207698 YP_003057157.1 CDS HELPY_0364 NC_012973.1 359124 361454 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(359124..361454) Helicobacter pylori B38 8208565 YP_003057158.1 CDS tkt NC_012973.1 361451 363376 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(361451..363376) Helicobacter pylori B38 8207699 YP_003057159.1 CDS ribF NC_012973.1 363423 364265 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(363423..364265) Helicobacter pylori B38 8209039 YP_003057160.1 CDS tlyA NC_012973.1 364231 364938 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11179345, 12018657; Product type e : enzyme; Pore-forming cytolysin complement(364231..364938) Helicobacter pylori B38 8208922 YP_003057161.1 CDS HELPY_0368 NC_012973.1 364938 365453 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(364938..365453) Helicobacter pylori B38 8209042 YP_003057162.1 CDS pyrB NC_012973.1 365520 366443 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 365520..366443 Helicobacter pylori B38 8207700 YP_003057163.1 CDS hofB NC_012973.1 366697 368136 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10633126, 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HofB 366697..368136 Helicobacter pylori B38 8208891 YP_003057164.1 CDS HELPY_0371 NC_012973.1 368227 369882 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9575204, 11546864; Product type t : transporter; ABC transporter ATP-binding protein; lipid A and glycerophospholipid transporter; membrane protein 368227..369882 Helicobacter pylori B38 8208637 YP_003057165.1 CDS HELPY_0372 NC_012973.1 369876 370499 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 369876..370499 Helicobacter pylori B38 8207701 YP_003057166.1 CDS HELPY_0373 NC_012973.1 370503 371072 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 370503..371072 Helicobacter pylori B38 8207702 YP_003057167.1 CDS nixA NC_012973.1 371195 372190 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11796600, 10692379, 11844775, 12890020, 16239520, 16452405, 9417070; Product type t : transporter; High-affinity nickel transporter 371195..372190 Helicobacter pylori B38 8207703 YP_003057168.1 CDS HELPY_0375 NC_012973.1 372194 372709 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(372194..372709) Helicobacter pylori B38 8208803 YP_003057169.1 CDS HELPY_0376 NC_012973.1 372844 374160 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 372844..374160 Helicobacter pylori B38 8207704 YP_003057170.1 CDS copP NC_012973.1 374809 375009 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9440521, 11031122; Product type f : factor; Copper-associated protein complement(374809..375009) Helicobacter pylori B38 8207705 YP_003057171.1 CDS copA NC_012973.1 375010 377235 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12060779, 9789554, 9244252, 8550601, 7752900, 9440521; Product type t : transporter; Copper-transporting ATPase/P-type transporting ATPase; membrane protein complement(375010..377235) Helicobacter pylori B38 8208439 YP_003057172.1 CDS pssA NC_012973.1 377232 377945 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15031650, 16294310; Product type e : enzyme; CDP-diacylglycerol--serine O-phosphatidyltransferase complement(377232..377945) Helicobacter pylori B38 8208437 YP_003057173.1 CDS ftsH2 NC_012973.1 378192 380090 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 18421140, 9560419, 8892813, 9244252, 8550601, 9440521; Product type e : enzyme; ATP-dependent zinc-metallo protease complement(378192..380090) Helicobacter pylori B38 8208882 YP_003057174.1 CDS prmA NC_012973.1 380099 381088 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase complement(380099..381088) Helicobacter pylori B38 8208564 YP_003057175.1 CDS cheY NC_012973.1 381089 381463 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16207913, 15664919, 11535789, 10722597, 10049806, 9485379; Product type r : regulator; Chemotactic response regulator, two-component system complement(381089..381463) Helicobacter pylori B38 8208876 YP_003057176.1 CDS horD NC_012973.1 381752 382354 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614; Product type m : membrane component; outer membrane protein HorD 381752..382354 Helicobacter pylori B38 8208424 YP_003057177.1 CDS HELPY_0385 NC_012973.1 382486 382893 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(382486..382893) Helicobacter pylori B38 8208344 YP_003057178.1 CDS HELPY_0386 NC_012973.1 382896 383138 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(382896..383138) Helicobacter pylori B38 8207706 YP_003057179.1 CDS gidB NC_012973.1 383132 383668 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(383132..383668) Helicobacter pylori B38 8207707 YP_003057180.1 CDS queA NC_012973.1 383665 384702 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(383665..384702) Helicobacter pylori B38 8208583 YP_003057181.1 CDS tatC NC_012973.1 384703 385449 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16487318, 16343541, 11591389, 11279240, 10593889, 16092529; Product type t : transporter; Sec-independent protein translocase protein; membrane protein complement(384703..385449) Helicobacter pylori B38 8208899 YP_003057182.1 CDS tatB NC_012973.1 385442 385909 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(385442..385909) Helicobacter pylori B38 8209027 YP_003057183.1 CDS ruvB NC_012973.1 385976 386986 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(385976..386986) Helicobacter pylori B38 8209026 YP_003057184.1 CDS panB NC_012973.1 386987 387799 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(386987..387799) Helicobacter pylori B38 8208997 YP_003057185.1 CDS HELPY_0393 NC_012973.1 387939 388670 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 387939..388670 Helicobacter pylori B38 8208836 YP_003057186.1 CDS HELPY_0394 NC_012973.1 388660 389514 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 388660..389514 Helicobacter pylori B38 8207708 YP_003057187.1 CDS HELPY_0395 NC_012973.1 389526 390467 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 389526..390467 Helicobacter pylori B38 8207709 YP_003057188.1 CDS HELPY_0396 NC_012973.1 390477 391799 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 390477..391799 Helicobacter pylori B38 8207710 YP_003057189.1 CDS minC NC_012973.1 391802 392389 D blocks the formation of polar Z-ring septums; septum formation inhibitor 391802..392389 Helicobacter pylori B38 8207711 YP_003057190.1 CDS lpxC NC_012973.1 392386 393273 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 392386..393273 Helicobacter pylori B38 8208758 YP_003057191.1 CDS HELPY_0399 NC_012973.1 393295 393768 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 393295..393768 Helicobacter pylori B38 8208740 YP_003057192.1 CDS thrB NC_012973.1 393822 394703 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 393822..394703 Helicobacter pylori B38 8207712 YP_003057193.1 CDS HELPY_0401 NC_012973.1 394690 394944 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 394690..394944 Helicobacter pylori B38 8209033 YP_003057194.1 CDS infB NC_012973.1 394941 397775 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 394941..397775 Helicobacter pylori B38 8207713 YP_003057195.1 CDS rbfA NC_012973.1 397775 398110 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 397775..398110 Helicobacter pylori B38 8208713 YP_003057196.1 CDS HELPY_0404 NC_012973.1 398103 398543 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 398103..398543 Helicobacter pylori B38 8208902 YP_003057197.1 CDS acs NC_012973.1 398652 400640 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(398652..400640) Helicobacter pylori B38 8207714 YP_003057198.1 CDS HELPY_0406 NC_012973.1 400839 401951 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8683579; Product type pe : enzyme; membrane-bound phosphoesterase; membrane protein 400839..401951 Helicobacter pylori B38 8208369 YP_003057199.1 CDS HELPY_0407 NC_012973.1 402292 402963 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; two-component response regulator 402292..402963 Helicobacter pylori B38 8207715 YP_003057200.1 CDS HELPY_0409 NC_012973.1 403109 403285 D Evidence 6 : Doubtful CDS; hypothetical protein 403109..403285 Helicobacter pylori B38 8207716 YP_003057201.1 CDS HELPY_0410 NC_012973.1 403292 403411 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(403292..403411) Helicobacter pylori B38 8207717 YP_003057202.1 CDS HELPY_0411 NC_012973.1 403765 404808 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9478130; Product type pe : enzyme; phosphoesterase RecJ-like complement(403765..404808) Helicobacter pylori B38 8207718 YP_003057203.1 CDS flhA NC_012973.1 404839 407040 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(404839..407040) Helicobacter pylori B38 8207719 YP_003057204.1 CDS rpsO NC_012973.1 407176 407448 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 407176..407448 Helicobacter pylori B38 8208529 YP_003057205.1 CDS HELPY_0414 NC_012973.1 407479 408768 D Evidence 4b : Only in Helicobacter genus; Product type m : membrane component; hypothetical protein 407479..408768 Helicobacter pylori B38 8208989 YP_003057206.1 CDS aroQ NC_012973.1 408899 409402 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 408899..409402 Helicobacter pylori B38 8207720 YP_003057207.1 CDS pepQ NC_012973.1 409416 410489 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15313226, 9797327, 9421914, 6336737; Product type e : enzyme; Proline dipeptidase 409416..410489 Helicobacter pylori B38 8208386 YP_003057208.1 CDS folK NC_012973.1 410486 410977 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9118956, 1325970; Product type e : enzyme; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 410486..410977 Helicobacter pylori B38 8208847 YP_003057209.1 CDS flhF NC_012973.1 410971 412344 D positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 410971..412344 Helicobacter pylori B38 8208552 YP_003057210.1 CDS HELPY_0419 NC_012973.1 412341 413225 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15361076; Product type pf : factor; ATPAse involved in the assembly of flagella 412341..413225 Helicobacter pylori B38 8208531 YP_003057211.1 CDS HELPY_0420 NC_012973.1 413230 413544 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 413230..413544 Helicobacter pylori B38 8207721 YP_003057212.1 CDS fliA NC_012973.1 413522 414289 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 413522..414289 Helicobacter pylori B38 8207722 YP_003057213.1 CDS fliM NC_012973.1 414282 415346 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 414282..415346 Helicobacter pylori B38 8208532 YP_003057214.1 CDS fliY NC_012973.1 415350 416213 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY 415350..416213 Helicobacter pylori B38 8208540 YP_003057215.1 CDS HELPY_0424 NC_012973.1 416242 416778 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 416242..416778 Helicobacter pylori B38 8208546 YP_003057216.1 CDS HELPY_0425 NC_012973.1 416775 417272 D Evidence 4b : Only in Helicobacter genus; hypothetical protein 416775..417272 Helicobacter pylori B38 8207723 YP_003057217.1 CDS fur NC_012973.1 417292 417744 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16369017, 15699202, 15221763, 12890020, 12748264, 12421315, 11796589; Product type r : regulator; ferric uptake regulation protein complement(417292..417744) Helicobacter pylori B38 8207724 YP_003057218.1 CDS HELPY_0427 NC_012973.1 417904 419079 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15037234, 15037233; Product type pe : enzyme; recombination factor protein RarA complement(417904..419079) Helicobacter pylori B38 8208569 YP_003057219.1 CDS HELPY_0428 NC_012973.1 419076 419447 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1988958, 2305262; Product type pr : regulator; transcriptional regulator, MerR family complement(419076..419447) Helicobacter pylori B38 8207725 YP_003057220.1 CDS dnaJ NC_012973.1 419457 420323 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10894735, 16585746, 16533811, 16487673, 15763707, 14984054, 12369934; Product type f : factor; Chaperone protein DnaJ complement(419457..420323) Helicobacter pylori B38 8207726 YP_003057221.1 CDS HELPY_0430 NC_012973.1 420491 421741 D Evidence 4b : Only in Helicobacter genus; hypothetical protein 420491..421741 Helicobacter pylori B38 8208466 YP_003057222.1 CDS HELPY_0431 NC_012973.1 421859 422695 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(421859..422695) Helicobacter pylori B38 8207727 YP_003057223.1 CDS HELPY_0432 NC_012973.1 422735 422896 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(422735..422896) Helicobacter pylori B38 8207728 YP_003057224.1 CDS HELPY_0433 NC_012973.1 422950 423846 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10966457; Product type pr : regulator; two-component response regulator complement(422950..423846) Helicobacter pylori B38 8207729 YP_003057225.1 CDS ispDF NC_012973.1 423868 425088 R [Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/ (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT); 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS) (MECDP-synthase)]; bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein complement(423868..425088) Helicobacter pylori B38 8207730 YP_003057226.1 CDS HELPY_0435 NC_012973.1 425110 426540 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15547264, 12065478, 16585775, 16369036, 16177372, 16085809; Product type pe : enzyme; serine protease, peptidase S1C HrtA/DegP2/Q/S family complement(425110..426540) Helicobacter pylori B38 8208717 YP_003057227.1 CDS HELPY_0436 NC_012973.1 426585 428027 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; transporter; amino-acid transporter, AAT family; membrane protein complement(426585..428027) Helicobacter pylori B38 8207731 YP_003057228.1 CDS pgsA NC_012973.1 428241 428780 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16514141, 10629182, 8576035; Product type e : enzyme; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(428241..428780) Helicobacter pylori B38 8207732 YP_003057229.1 CDS HELPY_0438 NC_012973.1 428777 429388 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(428777..429388) Helicobacter pylori B38 8208857 YP_003057230.1 CDS HELPY_0439 NC_012973.1 429398 430186 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(429398..430186) Helicobacter pylori B38 8207733 YP_003057231.1 CDS dapA NC_012973.1 430183 431085 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(430183..431085) Helicobacter pylori B38 8207734 YP_003057232.1 CDS HELPY_0441 NC_012973.1 431100 432434 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; zinc protease complement(431100..432434) Helicobacter pylori B38 8208448 YP_003057233.1 CDS pyrD NC_012973.1 432431 433486 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(432431..433486) Helicobacter pylori B38 8207735 YP_003057234.1 CDS ppk NC_012973.1 433523 435550 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(433523..435550) Helicobacter pylori B38 8208894 YP_003057235.1 CDS hsdS1 NC_012973.1 435987 437246 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9837717, 8336674, 3323532; Product type e : enzyme; type I restriction/modification specificity protein complement(435987..437246) Helicobacter pylori B38 8208343 YP_003057236.1 CDS hsdM1 NC_012973.1 437239 438870 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16614449, 16368872, 16207918, 15699185, 15475385, 3323532; Product type e : enzyme; type I restriction enzyme M protein complement(437239..438870) Helicobacter pylori B38 8208689 YP_003057237.1 CDS HELPY_0448 NC_012973.1 442070 443965 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(442070..443965) Helicobacter pylori B38 8207737 YP_003057238.1 CDS HELPY_0449 NC_012973.1 443991 444758 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(443991..444758) Helicobacter pylori B38 8207738 YP_003057239.1 CDS HELPY_0450 NC_012973.1 444768 445082 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(444768..445082) Helicobacter pylori B38 8207739 YP_003057240.1 CDS HELPY_0451 NC_012973.1 445084 446571 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(445084..446571) Helicobacter pylori B38 8207740 YP_003057241.1 CDS HELPY_0452 NC_012973.1 446583 447071 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(446583..447071) Helicobacter pylori B38 8207741 YP_003057242.1 CDS pepF NC_012973.1 447056 448792 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16391147, 11741842, 7674922, 7798200; Product type e : enzyme; Oligoendopeptidase F complement(447056..448792) Helicobacter pylori B38 8207742 YP_003057243.1 CDS HELPY_0455 NC_012973.1 448871 450139 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14604015, 10742217, 10092637, 9537504; Product type t : transporter; sodium/hydrogen exchanger complement(448871..450139) Helicobacter pylori B38 8208846 YP_003057244.1 CDS horE NC_012973.1 450468 451028 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 6322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HorE complement(450468..451028) Helicobacter pylori B38 8207743 YP_003057245.1 CDS modA NC_012973.1 451254 451994 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16385130, 11421278, 10446207; Product type t : transporter; ABC transporter substrate-binding protein 451254..451994 Helicobacter pylori B38 8208669 YP_003057246.1 CDS modB NC_012973.1 452016 452690 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16452441, 16385130, 15489438, 11421278; Product type t : transporter; ABC transporter permease; molybdate transporter; membrane protein 452016..452690 Helicobacter pylori B38 8208769 YP_003057247.1 CDS modC NC_012973.1 452687 453484 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14756792, 11421278, 7665460, 9325422; Product type t : transporter; ABC transporter ATP-binding protein; molybdate transporter 452687..453484 Helicobacter pylori B38 8208770 YP_003057248.1 CDS gltX NC_012973.1 453601 454992 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(453601..454992) Helicobacter pylori B38 8208771 YP_003057249.1 CDS hopJ NC_012973.1 455109 456209 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16220040, 16173498, 15918181, 12454856, 11211867, 9252185; Product type m : membrane component; outer membrane protein HopJ 455109..456209 Helicobacter pylori B38 8208591 YP_003057250.1 CDS hpyAVIIM NC_012973.1 456218 457855 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11133936, 11226310; Product type e : enzyme; type II adenine methyltransferase 456218..457855 Helicobacter pylori B38 8208657 YP_003057251.1 CDS HELPY_0463 NC_012973.1 457821 458669 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310, 11133936; Product type pe : enzyme; non-functional type II restriction endonuclease 457821..458669 Helicobacter pylori B38 8208684 YP_003057252.1 CDS typA NC_012973.1 458715 460514 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15297874, 15000390, 11683274, 9622352, 7737996; Product type f : factor; GTP-binding elongation factor protein, TypA subfamily 458715..460514 Helicobacter pylori B38 8207744 YP_003057253.1 CDS hpy99XIM NC_012973.1 460518 461564 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11226310, 11133936; Product type e : enzyme; type II cytosine specific DNA methyltransferase 460518..461564 Helicobacter pylori B38 8209067 YP_003057254.1 CDS HELPY_0466 NC_012973.1 461566 462318 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310; Product type pe : enzyme; non-functional type II restriction endonuclease 461566..462318 Helicobacter pylori B38 8208679 YP_003057255.1 CDS HELPY_0468 NC_012973.1 462525 463469 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16885452, 16879643, 16416177, 16298744, 16008611, 8955320, 2045782; Product type pe : enzyme; catalase complement(462525..463469) Helicobacter pylori B38 8207745 YP_003057256.1 CDS hofC NC_012973.1 463756 465342 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HofC 463756..465342 Helicobacter pylori B38 8207746 YP_003057257.1 CDS hofD NC_012973.1 465414 466826 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HofD 465414..466826 Helicobacter pylori B38 8208638 YP_003057258.1 CDS HELPY_0472 NC_012973.1 468877 469035 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 468877..469035 Helicobacter pylori B38 8207747 YP_003057259.1 CDS HELPY_0473 NC_012973.1 469204 469374 D Evidence 6 : Doubtful CDS; hypothetical protein 469204..469374 Helicobacter pylori B38 8207748 YP_003057260.1 CDS HELPY_0474 NC_012973.1 470089 470820 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(470089..470820) Helicobacter pylori B38 8207749 YP_003057261.1 CDS ruvC NC_012973.1 470953 471426 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 470953..471426 Helicobacter pylori B38 8207750 YP_003057262.1 CDS frpB1 NC_012973.1 471427 473802 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12704139, 12165031, 11886560, 11466300, 16914236, 11953376, 10217784; Product type m : membrane component; Iron-regulated outer membrane protein complement(471427..473802) Helicobacter pylori B38 8208998 YP_003057263.1 CDS katA NC_012973.1 474126 475643 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16885452, 16879643, 16416177, 16298744, 16008611, 8955320, 2045782; Product type e : enzyme; catalase 474126..475643 Helicobacter pylori B38 8208557 YP_003057264.1 CDS HELPY_0478 NC_012973.1 475788 476663 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 475788..476663 Helicobacter pylori B38 8208721 YP_003057265.1 CDS HELPY_0479 NC_012973.1 476748 476963 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 476748..476963 Helicobacter pylori B38 8207751 YP_003057266.1 CDS HELPY_0480 NC_012973.1 477016 477345 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9300819, 2155230; Product type pt : transporter; alkylphosphonate uptake protein PhnA complement(477016..477345) Helicobacter pylori B38 8207752 YP_003057267.1 CDS cdh NC_012973.1 477698 478432 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12000771, 11557141, 11016943, 2995360; Product type e : enzyme; CDP-diacylglycerol pyrophosphatase 477698..478432 Helicobacter pylori B38 8207753 YP_003057268.1 CDS flgE NC_012973.1 478641 480797 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 478641..480797 Helicobacter pylori B38 8208416 YP_003057269.1 CDS hypA NC_012973.1 480856 481209 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 480856..481209 Helicobacter pylori B38 8208519 YP_003057270.1 CDS HELPY_0484 NC_012973.1 481216 481677 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 481216..481677 Helicobacter pylori B38 8208699 YP_003057271.1 CDS lpxB NC_012973.1 481677 482759 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase 481677..482759 Helicobacter pylori B38 8207754 YP_003057272.1 CDS greA NC_012973.1 482800 483294 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 482800..483294 Helicobacter pylori B38 8208739 YP_003057273.1 CDS dut NC_012973.1 483284 483721 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 483284..483721 Helicobacter pylori B38 8208603 YP_003057274.1 CDS HELPY_0488 NC_012973.1 483718 484374 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 483718..484374 Helicobacter pylori B38 8208478 YP_003057275.1 CDS pgbB NC_012973.1 484379 485980 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14769936, 16513394; Product type f : factor; Plasminogen-binding protein PgbB 484379..485980 Helicobacter pylori B38 8207755 YP_003057276.1 CDS HELPY_0490 NC_012973.1 485985 486656 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 485985..486656 Helicobacter pylori B38 8208852 YP_003057277.1 CDS HELPY_0491 NC_012973.1 486656 487387 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 486656..487387 Helicobacter pylori B38 8207756 YP_003057278.1 CDS gmhB NC_012973.1 487377 487898 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12101286, 11751812; Product type e : enzyme; D,D-heptose 1,7-bisphosphate phosphatase 487377..487898 Helicobacter pylori B38 8207757 YP_003057279.1 CDS rfaD NC_012973.1 487907 488899 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15823050, 11751812, 11496013, 11349030, 9353016, 9119477; Product type e : enzyme; ADP-L-glycero-D-manno-heptose-6-epimerase 487907..488899 Helicobacter pylori B38 8208598 YP_003057280.1 CDS rfaE NC_012973.1 488896 490281 D [Includes: D-beta-D-heptose 7-phosphate kinase (D-beta-D-heptose 7-phosphotransferase); D-beta-D-heptose 1-phosphate adenosyltransferase ]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12803486, 12441667, 11496013, 10629197, 8755886; Product type e : enzyme; Bifunctional protein HldE 488896..490281 Helicobacter pylori B38 8208911 YP_003057281.1 CDS gmhA NC_012973.1 490274 490852 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 490274..490852 Helicobacter pylori B38 8208912 YP_003057282.1 CDS HELPY_0496 NC_012973.1 490855 491949 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(490855..491949) Helicobacter pylori B38 8208597 YP_003057283.1 CDS HELPY_0499 NC_012973.1 493565 493684 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 493565..493684 Helicobacter pylori B38 8207760 YP_003057284.1 CDS guaC NC_012973.1 493691 494668 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1979163, 1039060, 12923093, 2904262; Product type e : enzyme; guanosine 5'-monophosphate oxidoreductase complement(493691..494668) Helicobacter pylori B38 8207761 YP_003057285.1 CDS HELPY_0501 NC_012973.1 494866 496467 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1051871, 9593292; Product type t : transporter; ABC transporter ATP-binding protein 494866..496467 Helicobacter pylori B38 8208611 YP_003057286.1 CDS HELPY_0504 NC_012973.1 497440 498126 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(497440..498126) Helicobacter pylori B38 8207764 YP_003057287.1 CDS hsdS2 NC_012973.1 499895 500512 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12105196, 15699185, 2784505; Product type e : enzyme; type I R-M system specificity subunit 499895..500512 Helicobacter pylori B38 8207767 YP_003057288.1 CDS thiM NC_012973.1 503595 504374 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 503595..504374 Helicobacter pylori B38 8207769 YP_003057289.1 CDS thiD NC_012973.1 504371 505180 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15292217, 12794638, 11839308, 10382260, 10075431, 9244280; Product type e : enzyme; phosphomethylpyrimidine kinase (HMP-phosphate kinase) (HMP-P kinase) 504371..505180 Helicobacter pylori B38 8209032 YP_003057290.1 CDS thiE NC_012973.1 505173 505835 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 505173..505835 Helicobacter pylori B38 8209030 YP_003057291.1 CDS HELPY_0513 NC_012973.1 505944 506681 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(505944..506681) Helicobacter pylori B38 8209031 YP_003057292.1 CDS dfp NC_012973.1 506681 507958 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(506681..507958) Helicobacter pylori B38 8207770 YP_003057293.1 CDS flaA1 NC_012973.1 507955 508956 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16286454, 16077121, 15956417, 15322055, 15060026, 14562386, 10954725; Product type e : enzyme; UDP-GlcNAc C6 dehydratase/C5 epimerase complement(507955..508956) Helicobacter pylori B38 8208460 YP_003057294.1 CDS ompP1 NC_012973.1 508960 510723 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185, 8899706; Product type m : membrane component; outer membrane protein P1 complement(508960..510723) Helicobacter pylori B38 8208512 YP_003057295.1 CDS HELPY_0517 NC_012973.1 510720 511337 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(510720..511337) Helicobacter pylori B38 8208827 YP_003057296.1 CDS HELPY_0518 NC_012973.1 511357 511968 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(511357..511968) Helicobacter pylori B38 8207771 YP_003057297.1 CDS hup NC_012973.1 512571 512855 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15255779; Product type r : regulator; Histone-like DNA-binding protein HU complement(512571..512855) Helicobacter pylori B38 8208342 YP_003057298.1 CDS engA NC_012973.1 513007 514392 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(513007..514392) Helicobacter pylori B38 8208694 YP_003057299.1 CDS HELPY_0521 NC_012973.1 514469 515353 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 514469..515353 Helicobacter pylori B38 8207773 YP_003057300.1 CDS speE NC_012973.1 515440 516228 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 515440..516228 Helicobacter pylori B38 8207774 YP_003057301.1 CDS coaE NC_012973.1 516230 516820 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 516230..516820 Helicobacter pylori B38 8209017 YP_003057302.1 CDS gatA NC_012973.1 516880 518241 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 516880..518241 Helicobacter pylori B38 8208430 YP_003057303.1 CDS guaB NC_012973.1 518251 519696 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 518251..519696 Helicobacter pylori B38 8208577 YP_003057304.1 CDS atpB NC_012973.1 519818 520498 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 519818..520498 Helicobacter pylori B38 8208610 YP_003057305.1 CDS HELPY_0528 NC_012973.1 520820 521068 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2470643; Product type r : regulator; Nucleotide binding protein 520820..521068 Helicobacter pylori B38 8208394 YP_003057306.1 CDS HELPY_0529 NC_012973.1 521298 522119 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyltransferase, family 25 complement(521298..522119) Helicobacter pylori B38 8207775 YP_003057307.1 CDS trxR1 NC_012973.1 522476 523411 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16354674, 16213196, 15965489, 11222594, 10671551; Product type e : enzyme; thioredoxin reductase (TRXR) (TR) complement(522476..523411) Helicobacter pylori B38 8207776 YP_003057308.1 CDS trx1 NC_012973.1 523416 523736 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16354674, 16213196, 15965489, 11222594, 10671551; Product type c : carrier; thioredoxin 1 complement(523416..523736) Helicobacter pylori B38 8209063 YP_003057309.1 CDS HELPY_0533 NC_012973.1 523825 524169 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(523825..524169) Helicobacter pylori B38 8209060 YP_003057310.1 CDS hom NC_012973.1 524170 525435 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(524170..525435) Helicobacter pylori B38 8207777 YP_003057311.1 CDS uvrC NC_012973.1 525446 527230 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(525446..527230) Helicobacter pylori B38 8208645 YP_003057312.1 CDS HELPY_0536 NC_012973.1 527231 527692 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(527231..527692) Helicobacter pylori B38 8209085 YP_003057313.1 CDS HELPY_0538 NC_012973.1 527875 528516 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2691838, 2515417, 7592481; Product type e : enzyme; ABC transporter ATP-binding protein; osmoprotection ABC transporter involved in glycine/betaine/L-proline transport complement(527875..528516) Helicobacter pylori B38 8207778 YP_003057314.1 CDS HELPY_0539 NC_012973.1 528520 530190 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10216873; Product type t : transporter; ABC transporter permease; betaine/proline/choline transporter; membrane protein complement(528520..530190) Helicobacter pylori B38 8207779 YP_003057315.1 CDS HELPY_0540 NC_012973.1 530250 530696 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(530250..530696) Helicobacter pylori B38 8207780 YP_003057316.1 CDS motB NC_012973.1 530693 531466 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(530693..531466) Helicobacter pylori B38 8207781 YP_003057317.1 CDS motA NC_012973.1 531469 532242 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(531469..532242) Helicobacter pylori B38 8208776 YP_003057318.1 CDS moeB NC_012973.1 532258 533025 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16388576, 15896804, 12234097, 11290749, 11463785, 11438688, 11713534; Product type e : enzyme; molybdopterin/thiamine biosynthesis activator complement(532258..533025) Helicobacter pylori B38 8208775 YP_003057319.1 CDS HELPY_0544 NC_012973.1 533026 533643 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase complement(533026..533643) Helicobacter pylori B38 8208773 YP_003057320.1 CDS HELPY_0545 NC_012973.1 533775 534785 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 533775..534785 Helicobacter pylori B38 8207782 YP_003057321.1 CDS HELPY_0546 NC_012973.1 535147 535473 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 535147..535473 Helicobacter pylori B38 8207783 YP_003057322.1 CDS HELPY_0547 NC_012973.1 535452 536054 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; N-6 adenine methyltransferase 535452..536054 Helicobacter pylori B38 8207784 YP_003057323.1 CDS fliL NC_012973.1 536069 536620 D interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 536069..536620 Helicobacter pylori B38 8207785 YP_003057324.1 CDS acpS NC_012973.1 536627 536983 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 536627..536983 Helicobacter pylori B38 8208539 YP_003057325.1 CDS HELPY_0553 NC_012973.1 539586 540206 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase complement(539586..540206) Helicobacter pylori B38 8207788 YP_003057326.1 CDS HELPY_0554 NC_012973.1 540288 541142 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817494; Product type pe : enzyme; glycosyl transferase, family 25; LPS biosynthesis protein 540288..541142 Helicobacter pylori B38 8207789 YP_003057327.1 CDS ribBA NC_012973.1 541309 542343 D bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 541309..542343 Helicobacter pylori B38 8207790 YP_003057328.1 CDS HELPY_0557 NC_012973.1 542430 543269 D Evidence 4a : Only in Helicobacter pylori; Product type pm : membrane component; hypothetical protein 542430..543269 Helicobacter pylori B38 8208918 YP_003057329.1 CDS ribA NC_012973.1 543358 543936 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 543358..543936 Helicobacter pylori B38 8207791 YP_003057330.1 CDS moaD NC_012973.1 544013 544234 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15709772, 12372836, 8514782; Product type e : enzyme; molybdopterin-converting factor subunit 1 544013..544234 Helicobacter pylori B38 8208917 YP_003057331.1 CDS moaE NC_012973.1 544235 544672 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12372836, 8514782; Product type e : enzyme; MPT synthase subunit 2 544235..544672 Helicobacter pylori B38 8208764 YP_003057332.1 CDS mogA NC_012973.1 544685 545215 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 544685..545215 Helicobacter pylori B38 8208765 YP_003057333.1 CDS moaC NC_012973.1 545225 545701 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 545225..545701 Helicobacter pylori B38 8208774 YP_003057334.1 CDS hpaA NC_012973.1 545820 546602 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16428735, 16041003, 15849827, 12819067, 11710844, 9287032, 7592366; Product type lp : lipoprotein; Neuraminyllactose-binding hemagglutinin HpaA 545820..546602 Helicobacter pylori B38 8208763 YP_003057335.1 CDS horG NC_012973.1 546631 547467 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16181353, 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HorG 546631..547467 Helicobacter pylori B38 8208674 YP_003057336.1 CDS tig NC_012973.1 547579 548934 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 547579..548934 Helicobacter pylori B38 8208671 YP_003057337.1 CDS clpP NC_012973.1 548952 549542 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 548952..549542 Helicobacter pylori B38 8209037 YP_003057338.1 CDS def NC_012973.1 549547 550071 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 549547..550071 Helicobacter pylori B38 8208427 YP_003057339.1 CDS HELPY_0568 NC_012973.1 550077 551597 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Mg chelatase-related protein; ComM protein 550077..551597 Helicobacter pylori B38 8208457 YP_003057340.1 CDS cadA NC_012973.1 551622 553682 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10417643, 10577484, 9789554, 8550601, 16835223, 16491024, 16388822; Product type t : transporter; Cadmium, zinc and cobalt-transporting ATPase 551622..553682 Helicobacter pylori B38 8207792 YP_003057341.1 CDS HELPY_0571 NC_012973.1 554109 555338 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 complement(554109..555338) Helicobacter pylori B38 8208411 YP_003057342.1 CDS HELPY_0572 NC_012973.1 555325 555957 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 complement(555325..555957) Helicobacter pylori B38 8207793 YP_003057343.1 CDS HELPY_0573 NC_012973.1 555954 556139 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(555954..556139) Helicobacter pylori B38 8207794 YP_003057344.1 CDS HELPY_0574 NC_012973.1 556141 556398 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(556141..556398) Helicobacter pylori B38 8207795 YP_003057345.1 CDS hofF NC_012973.1 557677 559176 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HofF complement(557677..559176) Helicobacter pylori B38 8207797 YP_003057346.1 CDS lolC NC_012973.1 559456 560688 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16585747, 12823819, 12198129, 10783239, 10783239; Product type t : transporter; ABC transporter permease; lipoprotein release system transmembrane protein LolC; membrane protein complement(559456..560688) Helicobacter pylori B38 8208641 YP_003057347.1 CDS secA NC_012973.1 560678 563275 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(560678..563275) Helicobacter pylori B38 8208734 YP_003057348.1 CDS lolA NC_012973.1 563423 563977 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 563423..563977 Helicobacter pylori B38 8209003 YP_003057349.1 CDS HELPY_0581 NC_012973.1 564471 564998 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 564471..564998 Helicobacter pylori B38 8208733 YP_003057350.1 CDS hofE NC_012973.1 565005 566372 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185, 7534278; Product type m : membrane component; outermembrane protein HofE complement(565005..566372) Helicobacter pylori B38 8207798 YP_003057351.1 CDS HELPY_0583 NC_012973.1 566466 567755 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(566466..567755) Helicobacter pylori B38 8208640 YP_003057352.1 CDS HELPY_0584 NC_012973.1 568015 568284 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(568015..568284) Helicobacter pylori B38 8207799 YP_003057353.1 CDS acnB NC_012973.1 568362 570920 R catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase complement(568362..570920) Helicobacter pylori B38 8207800 YP_003057354.1 CDS HELPY_0586 NC_012973.1 571051 571734 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 571051..571734 Helicobacter pylori B38 8208365 YP_003057355.1 CDS pyrH NC_012973.1 571843 572565 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 571843..572565 Helicobacter pylori B38 8207801 YP_003057356.1 CDS rpoZ NC_012973.1 572607 572831 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 572607..572831 Helicobacter pylori B38 8208898 YP_003057357.1 CDS spoT NC_012973.1 572818 575145 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16672627, 2005135, 9882669, 16467149, 16343907, 15853883; Product type e : enzyme; guanosine-3', 5'-bis(diphosphate)3'-pyrophosphohydrolase /guanosine-3',5'-bis(diphosphate) synthetase II 572818..575145 Helicobacter pylori B38 8208974 YP_003057358.1 CDS tyrS NC_012973.1 575169 576377 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 575169..576377 Helicobacter pylori B38 8209018 YP_003057359.1 CDS HELPY_0591 NC_012973.1 576394 577485 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 576394..577485 Helicobacter pylori B38 8209069 YP_003057360.1 CDS amiA NC_012973.1 577492 578838 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17085576; Product type e : enzyme; N-acetylmuramoyl-L-alanine amidase 577492..578838 Helicobacter pylori B38 8207802 YP_003057361.1 CDS HELPY_0593 NC_012973.1 578857 579594 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 578857..579594 Helicobacter pylori B38 8208374 YP_003057362.1 CDS flhB NC_012973.1 579681 580757 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(579681..580757) Helicobacter pylori B38 8207803 YP_003057363.1 CDS mobA NC_012973.1 580750 581355 R MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A complement(580750..581355) Helicobacter pylori B38 8208530 YP_003057364.1 CDS moaA NC_012973.1 581440 582405 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 581440..582405 Helicobacter pylori B38 8208766 YP_003057365.1 CDS HELPY_0599 NC_012973.1 583527 583835 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 583527..583835 Helicobacter pylori B38 8207805 YP_003057366.1 CDS HELPY_0602 NC_012973.1 585209 586090 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16820862; Product type pf : factor; signal recognition particule receptor FtsY complement(585209..586090) Helicobacter pylori B38 8207808 YP_003057367.1 CDS HELPY_0603 NC_012973.1 586097 586663 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(586097..586663) Helicobacter pylori B38 8207809 YP_003057368.1 CDS HELPY_0604 NC_012973.1 586824 587426 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 586824..587426 Helicobacter pylori B38 8207810 YP_003057369.1 CDS HELPY_0605 NC_012973.1 587404 588915 D protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 587404..588915 Helicobacter pylori B38 8207811 YP_003057370.1 CDS HELPY_0606 NC_012973.1 588916 590169 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16189122, 15716425, 14695443, 14679249; Product type t : transporter; multidrug efflux protein MatE; membrane protein complement(588916..590169) Helicobacter pylori B38 8207812 YP_003057371.1 CDS HELPY_0607 NC_012973.1 590232 591545 R Evidence 4c : Only in epsilon proteobacteria; Product type m : membrane component; hypothetical protein complement(590232..591545) Helicobacter pylori B38 8207813 YP_003057372.1 CDS HELPY_0608 NC_012973.1 591671 592549 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11380987, 7987228; Product type pe : enzyme; carbon-nitrogen hydrolase complement(591671..592549) Helicobacter pylori B38 8207814 YP_003057373.1 CDS HELPY_0609 NC_012973.1 592553 592699 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(592553..592699) Helicobacter pylori B38 8207815 YP_003057374.1 CDS HELPY_0610 NC_012973.1 592725 593384 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12234097, 11713534; Product type pf : factor; molybdenum biosynthesis cofactor, MoeB/ThiF family complement(592725..593384) Helicobacter pylori B38 8207816 YP_003057375.1 CDS HELPY_0611 NC_012973.1 593438 593677 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(593438..593677) Helicobacter pylori B38 8207817 YP_003057376.1 CDS fliS NC_012973.1 593664 594044 R flagellin specific chaperone; flagellar protein FliS complement(593664..594044) Helicobacter pylori B38 8207818 YP_003057377.1 CDS fliD NC_012973.1 594085 596142 R involved in flagellin assembly; flagellar capping protein complement(594085..596142) Helicobacter pylori B38 8208545 YP_003057378.1 CDS flaG NC_012973.1 596159 596518 R possibly involved in flagella export; flagellar protein FlaG complement(596159..596518) Helicobacter pylori B38 8208533 YP_003057379.1 CDS HELPY_0615 NC_012973.1 596611 597813 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(596611..597813) Helicobacter pylori B38 8208514 YP_003057380.1 CDS HELPY_0616 NC_012973.1 597806 598612 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16416128, 14729705, 11430412; Product type t : transporter; ABC transporter permease complement(597806..598612) Helicobacter pylori B38 8207819 YP_003057381.1 CDS HELPY_0617 NC_012973.1 598599 599270 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16416128, 14729705, 11430412, 9593292, 10518715, 3025556; Product type t : transporter; ABC transporter ATP-binding protein; cell division protein FtsE complement(598599..599270) Helicobacter pylori B38 8207820 YP_003057382.1 CDS HELPY_0618 NC_012973.1 599267 600442 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(599267..600442) Helicobacter pylori B38 8207821 YP_003057383.1 CDS HELPY_0619 NC_012973.1 600453 601667 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(600453..601667) Helicobacter pylori B38 8207822 YP_003057384.1 CDS rluD2 NC_012973.1 601669 602652 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15928344, 15078091, 14730022, 14659742, 14501142, 9814761, 9843401; Product type e : enzyme; Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) complement(601669..602652) Helicobacter pylori B38 8207823 YP_003057385.1 CDS rodA NC_012973.1 604013 605158 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15612918, 12596863, 11976312, 9922463, 962235, 7575501, 250943; Product type cp : cell process; Rod shape-determining protein RodA; membrane protein 604013..605158 Helicobacter pylori B38 8207826 YP_003057386.1 CDS prs NC_012973.1 605224 606180 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(605224..606180) Helicobacter pylori B38 8208346 YP_003057387.1 CDS HELPY_0626 NC_012973.1 606245 606730 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12119013, 9164465, 1472710; Product type pe : enzyme; HIT family protein complement(606245..606730) Helicobacter pylori B38 8208879 YP_003057388.1 CDS murF NC_012973.1 606740 608221 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15694856, 15694856, 8973200, 2668880; Product type e : enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; membrane protein complement(606740..608221) Helicobacter pylori B38 8207827 YP_003057389.1 CDS HELPY_0628 NC_012973.1 608208 608933 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(608208..608933) Helicobacter pylori B38 8208788 YP_003057390.1 CDS ddl NC_012973.1 608934 609983 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(608934..609983) Helicobacter pylori B38 8207828 YP_003057391.1 CDS pgpA NC_012973.1 610055 610531 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1309518, 2846511, 2846510; Product type e : enzyme; phosphatidylglycerophosphatase A complement(610055..610531) Helicobacter pylori B38 8208455 YP_003057392.1 CDS HELPY_0631 NC_012973.1 610679 611788 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8482384; Product type pe : enzyme; class V aminotransferase 610679..611788 Helicobacter pylori B38 8208856 YP_003057393.1 CDS HELPY_0632 NC_012973.1 611797 612258 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 692401, 9743633, 3886014; Product type pe : enzyme; nucleotide phosphoribosyl transferase 611797..612258 Helicobacter pylori B38 8207829 YP_003057394.1 CDS HELPY_0633 NC_012973.1 612260 613579 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 612260..613579 Helicobacter pylori B38 8207830 YP_003057395.1 CDS HELPY_0636 NC_012973.1 615500 617218 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10768971; Product type pf : factor; LeoA protein 615500..617218 Helicobacter pylori B38 8207833 YP_003057396.1 CDS HELPY_0637 NC_012973.1 617323 617628 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 617323..617628 Helicobacter pylori B38 8207834 YP_003057397.1 CDS HELPY_0638 NC_012973.1 617637 618704 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 617637..618704 Helicobacter pylori B38 8207835 YP_003057398.1 CDS tilS NC_012973.1 618740 619756 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16039592, 15124629; Product type e : enzyme; tRNA(Ile)-lysidine synthase 618740..619756 Helicobacter pylori B38 8207836 YP_003057399.1 CDS HELPY_0640 NC_012973.1 619849 620835 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 619849..620835 Helicobacter pylori B38 8209038 YP_003057400.1 CDS HELPY_0641 NC_012973.1 620832 621722 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type pm : membrane component; outer membrane protein 620832..621722 Helicobacter pylori B38 8207837 YP_003057401.1 CDS hopP NC_012973.1 621942 623909 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HopP 621942..623909 Helicobacter pylori B38 8207838 YP_003057402.1 CDS dcuA NC_012973.1 623984 625315 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(623984..625315) Helicobacter pylori B38 8208663 YP_003057403.1 CDS ansB NC_012973.1 625444 626436 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2407723, 8898907; Product type e : enzyme; L-asparaginase 625444..626436 Helicobacter pylori B38 8208454 YP_003057404.1 CDS HELPY_0645 NC_012973.1 626501 626920 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(626501..626920) Helicobacter pylori B38 8208377 YP_003057405.1 CDS HELPY_0646 NC_012973.1 627101 627562 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(627101..627562) Helicobacter pylori B38 8207839 YP_003057406.1 CDS HELPY_0647 NC_012973.1 627593 628078 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(627593..628078) Helicobacter pylori B38 8207840 YP_003057407.1 CDS HELPY_0648 NC_012973.1 628279 628911 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; L-lysine exporter; membrane protein 628279..628911 Helicobacter pylori B38 8207841 YP_003057408.1 CDS dnaX NC_012973.1 628980 630692 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 628980..630692 Helicobacter pylori B38 8207842 YP_003057409.1 CDS HELPY_0650 NC_012973.1 630689 631090 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATPase 630689..631090 Helicobacter pylori B38 8208471 YP_003057410.1 CDS HELPY_0651 NC_012973.1 631103 631825 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter ATP-binding protein 631103..631825 Helicobacter pylori B38 8207843 YP_003057411.1 CDS rpoN NC_012973.1 631828 633072 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 631828..633072 Helicobacter pylori B38 8207844 YP_003057412.1 CDS HELPY_0655 NC_012973.1 633760 634980 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(633760..634980) Helicobacter pylori B38 8207846 YP_003057413.1 CDS homA NC_012973.1 635170 637134 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185, 7534278; Product type m : membrane component; outer membrane protein HomA complement(635170..637134) Helicobacter pylori B38 8207847 YP_003057414.1 CDS HELPY_0657 NC_012973.1 637359 638261 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(637359..638261) Helicobacter pylori B38 8208646 YP_003057415.1 CDS HELPY_0658 NC_012973.1 638464 638808 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(638464..638808) Helicobacter pylori B38 8207848 YP_003057416.1 CDS mraW NC_012973.1 638829 639755 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12153713, 10876091, 10572301, 9721276; Product type e : enzyme; S-adenosyl-methyltransferase MraW complement(638829..639755) Helicobacter pylori B38 8207849 YP_003057417.1 CDS hopE NC_012973.1 639933 640754 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7559328, 16102915, 15939494, 14742532, 12454143, 16322107, 16173498; Product type m : membrane component; outer membrane protein HopE complement(639933..640754) Helicobacter pylori B38 8207850 YP_003057418.1 CDS uvrA NC_012973.1 640919 643744 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 640919..643744 Helicobacter pylori B38 8208652 YP_003057419.1 CDS HELPY_0662 NC_012973.1 643775 643891 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 643775..643891 Helicobacter pylori B38 8209083 YP_003057420.1 CDS flgR NC_012973.1 644987 646132 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; transcriptional activator complement(644987..646132) Helicobacter pylori B38 8207853 YP_003057421.1 CDS HELPY_0667 NC_012973.1 646129 646602 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(646129..646602) Helicobacter pylori B38 8208528 YP_003057422.1 CDS gyrA NC_012973.1 646602 649085 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(646602..649085) Helicobacter pylori B38 8207854 YP_003057423.1 CDS dgkA NC_012973.1 649101 649487 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8071224, 12923107, 3015952, 3015952; Product type e : enzyme; Diacylglycerol kinase complement(649101..649487) Helicobacter pylori B38 8208612 YP_003057424.1 CDS HELPY_0670 NC_012973.1 649480 650508 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(649480..650508) Helicobacter pylori B38 8208461 YP_003057425.1 CDS HELPY_0671 NC_012973.1 650519 650710 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(650519..650710) Helicobacter pylori B38 8207855 YP_003057426.1 CDS HELPY_0673 NC_012973.1 650897 651397 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(650897..651397) Helicobacter pylori B38 8207856 YP_003057427.1 CDS HELPY_0674 NC_012973.1 651414 653711 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10222578, 1732229; Product type pe : enzyme; N-methylhydantoinase complement(651414..653711) Helicobacter pylori B38 8207857 YP_003057428.1 CDS HELPY_0678 NC_012973.1 656323 657333 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(656323..657333) Helicobacter pylori B38 8207861 YP_003057429.1 CDS atoE NC_012973.1 657462 658832 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11267787, 2883171, 3025185; Product type t : transporter; Short-chain fatty acid transport protein, scFAT family; membrane protein complement(657462..658832) Helicobacter pylori B38 8207862 YP_003057430.1 CDS scoB NC_012973.1 658846 659469 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9325289, 10091606, 10477312, 10477311, 10809701, 1624453, 9083111; Product type c : carrier; succinyl-CoA-transferase subunit B complement(658846..659469) Helicobacter pylori B38 8208392 YP_003057431.1 CDS scoA NC_012973.1 659466 660164 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9325289, 10091606, 10477312, 10477311, 10809701, 1624453, 9083111; Product type c : carrier; succinyl-CoA-transferase subunit A complement(659466..660164) Helicobacter pylori B38 8209000 YP_003057432.1 CDS HELPY_0683 NC_012973.1 660175 661350 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; acetyl coenzyme A acetyltransferase complement(660175..661350) Helicobacter pylori B38 8208999 YP_003057433.1 CDS HELPY_0684 NC_012973.1 661634 662446 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(661634..662446) Helicobacter pylori B38 8207863 YP_003057434.1 CDS feoB NC_012973.1 662590 664518 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16041003, 15270747, 16718600, 10931324, 8407793, 16430693, 12781516; Product type t : transporter; Ferrous iron transport protein B; membrane protein 662590..664518 Helicobacter pylori B38 8207864 YP_003057435.1 CDS fecA1 NC_012973.1 664769 667072 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2836368, 10633096, 10713425, 12165031, 16718597, 16333751, 16193283; Product type pt : transporter; Iron(III) dicitrate transport protein FecA 664769..667072 Helicobacter pylori B38 8208505 YP_003057436.1 CDS fliP NC_012973.1 667109 667855 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(667109..667855) Helicobacter pylori B38 8208501 YP_003057437.1 CDS glmU NC_012973.1 667944 669245 D [UDP-N-acetylglucosamine pyrophosphorylase N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase]; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 667944..669245 Helicobacter pylori B38 8208542 YP_003057438.1 CDS HELPY_0689 NC_012973.1 669446 669796 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 669446..669796 Helicobacter pylori B38 8208587 YP_003057439.1 CDS HELPY_0690 NC_012973.1 669821 670303 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 669821..670303 Helicobacter pylori B38 8207865 YP_003057440.1 CDS nrdA NC_012973.1 670471 672837 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 670471..672837 Helicobacter pylori B38 8207866 YP_003057441.1 CDS HELPY_0692 NC_012973.1 672899 673846 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 672899..673846 Helicobacter pylori B38 8208804 YP_003057442.1 CDS HELPY_0693 NC_012973.1 673959 674726 D Evidence 4c : Only in epsilon proteobacteria; Product type m : membrane component; hypothetical protein 673959..674726 Helicobacter pylori B38 8207867 YP_003057443.1 CDS ogt NC_012973.1 674730 675236 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12517410; Product type e : enzyme; methylated-DNA--protein-cysteine methyltransferase (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase) 674730..675236 Helicobacter pylori B38 8207868 YP_003057444.1 CDS HELPY_0695 NC_012973.1 675301 676371 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; integrase/recombinase complement(675301..676371) Helicobacter pylori B38 8208826 YP_003057445.1 CDS HELPY_0696 NC_012973.1 676385 676978 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(676385..676978) Helicobacter pylori B38 8207869 YP_003057446.1 CDS aspB NC_012973.1 677475 678647 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(677475..678647) Helicobacter pylori B38 8207870 YP_003057447.1 CDS horF NC_012973.1 678810 679622 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HorF complement(678810..679622) Helicobacter pylori B38 8208389 YP_003057448.1 CDS HELPY_0700 NC_012973.1 683721 684950 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 complement(683721..684950) Helicobacter pylori B38 8207871 YP_003057449.1 CDS HELPY_0701 NC_012973.1 684937 685569 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 complement(684937..685569) Helicobacter pylori B38 8207872 YP_003057450.1 CDS HELPY_0702 NC_012973.1 685566 685751 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(685566..685751) Helicobacter pylori B38 8207873 YP_003057451.1 CDS HELPY_0703 NC_012973.1 685753 686010 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(685753..686010) Helicobacter pylori B38 8207874 YP_003057452.1 CDS HELPY_0705 NC_012973.1 687102 688403 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; anaerobic glycerol-3-phosphate dehydrogenase (G-3-P dehydrogenase) complement(687102..688403) Helicobacter pylori B38 8207876 YP_003057453.1 CDS hemN NC_012973.1 688400 689773 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(688400..689773) Helicobacter pylori B38 8207877 YP_003057454.1 CDS HELPY_0707 NC_012973.1 689773 690288 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(689773..690288) Helicobacter pylori B38 8208632 YP_003057455.1 CDS aroC NC_012973.1 690325 691422 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(690325..691422) Helicobacter pylori B38 8207878 YP_003057456.1 CDS rnc NC_012973.1 691419 692117 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(691419..692117) Helicobacter pylori B38 8208382 YP_003057457.1 CDS rnhA NC_012973.1 692129 692560 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(692129..692560) Helicobacter pylori B38 8208928 YP_003057458.1 CDS HELPY_0711 NC_012973.1 692547 693566 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(692547..693566) Helicobacter pylori B38 8208929 YP_003057459.1 CDS HELPY_0712 NC_012973.1 693577 694839 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(693577..694839) Helicobacter pylori B38 8207879 YP_003057460.1 CDS gatB NC_012973.1 694839 696263 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(694839..696263) Helicobacter pylori B38 8207880 YP_003057461.1 CDS HELPY_0714 NC_012973.1 696263 697525 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(696263..697525) Helicobacter pylori B38 8208578 YP_003057462.1 CDS HELPY_0715 NC_012973.1 697570 698631 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(697570..698631) Helicobacter pylori B38 8207881 YP_003057463.1 CDS HELPY_0716 NC_012973.1 698633 701413 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; surface antigen protein complement(698633..701413) Helicobacter pylori B38 8207882 YP_003057464.1 CDS HELPY_0717 NC_012973.1 701451 702533 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(701451..702533) Helicobacter pylori B38 8207883 YP_003057465.1 CDS pfr NC_012973.1 702831 703334 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12065536, 9782498; Product type c : carrier; Nonheme iron-containing ferritin (iron storage protein) 702831..703334 Helicobacter pylori B38 8207884 YP_003057466.1 CDS serB NC_012973.1 703350 703973 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16269752, 2997734; Product type e : enzyme; phosphoserine phosphatase 703350..703973 Helicobacter pylori B38 8208851 YP_003057467.1 CDS futB NC_012973.1 704013 705422 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16477004, 15058985, 10496917; Product type e : enzyme; Alpha1,3-fucosyltransferase 704013..705422 Helicobacter pylori B38 8209011 YP_003057468.1 CDS HELPY_0721 NC_012973.1 705431 706060 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transferase complement(705431..706060) Helicobacter pylori B38 8208572 YP_003057469.1 CDS aspA NC_012973.1 706066 707472 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(706066..707472) Helicobacter pylori B38 8207885 YP_003057470.1 CDS murA NC_012973.1 707530 708798 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(707530..708798) Helicobacter pylori B38 8208388 YP_003057471.1 CDS HELPY_0724 NC_012973.1 708801 709208 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(708801..709208) Helicobacter pylori B38 8208783 YP_003057472.1 CDS galU NC_012973.1 709220 710041 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16132460, 15240254, 15213167; Product type e : enzyme; UTP-glucose-1-phosphate uridylyltransferase complement(709220..710041) Helicobacter pylori B38 8207886 YP_003057473.1 CDS HELPY_0726 NC_012973.1 710038 711720 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; soluble lytic murein transglycosylase complement(710038..711720) Helicobacter pylori B38 8208575 YP_003057474.1 CDS HELPY_0727 NC_012973.1 711729 712022 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(711729..712022) Helicobacter pylori B38 8207887 YP_003057475.1 CDS gltX2 NC_012973.1 712019 713338 R charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase complement(712019..713338) Helicobacter pylori B38 8207888 YP_003057476.1 CDS frxA NC_012973.1 713503 714156 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16426819, 15856372, 15496391, 1549639, 12648728; Product type e : enzyme; NAD(P)H-flavin oxidoreductase complement(713503..714156) Helicobacter pylori B38 8208592 YP_003057477.1 CDS HELPY_0730 NC_012973.1 714158 715015 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12729017; Product type pe : enzyme; 3-hydroxyacid dehydrogenase complement(714158..715015) Helicobacter pylori B38 8208561 YP_003057478.1 CDS HELPY_0731 NC_012973.1 715183 716391 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10684583; Product type pe : enzyme; polynucleotide adenylyltransferase; poly(A) polymerase complement(715183..716391) Helicobacter pylori B38 8207889 YP_003057479.1 CDS HELPY_0732 NC_012973.1 716454 717140 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 716454..717140 Helicobacter pylori B38 8207890 YP_003057480.1 CDS hopH NC_012973.1 717209 718183 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 15457576, 15131212, 10852959; Product type m : membrane component; outer membrane protein HopH complement(717209..718183) Helicobacter pylori B38 8207891 YP_003057481.1 CDS HELPY_0734 NC_012973.1 718314 718766 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 718314..718766 Helicobacter pylori B38 8208655 YP_003057482.1 CDS HELPY_0735 NC_012973.1 718903 719316 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 718903..719316 Helicobacter pylori B38 8207892 YP_003057483.1 CDS HELPY_0736 NC_012973.1 719321 720859 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(719321..720859) Helicobacter pylori B38 8207893 YP_003057484.1 CDS hydD NC_012973.1 720861 721397 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233; Product type e : enzyme; Endoprotease involved hydrogenase maturation complement(720861..721397) Helicobacter pylori B38 8207894 YP_003057485.1 CDS hydC NC_012973.1 721394 722068 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 8764511; Product type e : enzyme; Quinone-reactive Ni/Fe hydrogenase cytochrome b subunit complement(721394..722068) Helicobacter pylori B38 8208698 YP_003057486.1 CDS hydB NC_012973.1 722081 723817 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 11123699, 8764511; Product type e : enzyme; Quinone-reactive Ni/Fe-hydrogenase large chain complement(722081..723817) Helicobacter pylori B38 8208697 YP_003057487.1 CDS hydA NC_012973.1 723827 724981 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11123699, 8764511; Product type e : enzyme; Quinone-reactive Ni/Fe hydrogenase small subunit complement(723827..724981) Helicobacter pylori B38 8208696 YP_003057488.1 CDS mdaB NC_012973.1 725144 725728 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14977943, 16511004, 8611590; Product type e : enzyme; NAD(P)H oxidoreductase (NADPH quinone reductase) 725144..725728 Helicobacter pylori B38 8208695 YP_003057489.1 CDS HELPY_0744 NC_012973.1 728059 729117 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(728059..729117) Helicobacter pylori B38 8207896 YP_003057490.1 CDS dapD NC_012973.1 729129 730334 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10508663, 10850974, 9012664; Product type e : enzyme; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase complement(729129..730334) Helicobacter pylori B38 8207897 YP_003057491.1 CDS ispG NC_012973.1 730337 731416 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(730337..731416) Helicobacter pylori B38 8208450 YP_003057492.1 CDS aspB NC_012973.1 731536 732663 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12670965; Product type e : enzyme; hypothetical protein 731536..732663 Helicobacter pylori B38 8208719 YP_003057493.1 CDS murC NC_012973.1 732656 734005 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 732656..734005 Helicobacter pylori B38 8208390 YP_003057494.1 CDS HELPY_0749 NC_012973.1 734005 734382 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 734005..734382 Helicobacter pylori B38 8208785 YP_003057495.1 CDS mutS NC_012973.1 734389 736638 D MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 734389..736638 Helicobacter pylori B38 8207898 YP_003057496.1 CDS ppa NC_012973.1 736780 737301 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(736780..737301) Helicobacter pylori B38 8208791 YP_003057497.1 CDS adk NC_012973.1 738673 739248 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(738673..739248) Helicobacter pylori B38 8207900 YP_003057498.1 CDS aspS NC_012973.1 739265 740998 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(739265..740998) Helicobacter pylori B38 8208370 YP_003057499.1 CDS cheV2 NC_012973.1 741033 741974 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11535789, 8169224, 8169223; Product type pf : factor; Chemotaxis protein complement(741033..741974) Helicobacter pylori B38 8208391 YP_003057500.1 CDS ligA NC_012973.1 742052 744022 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 742052..744022 Helicobacter pylori B38 8208421 YP_003057501.1 CDS HELPY_0758 NC_012973.1 744176 744508 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 744176..744508 Helicobacter pylori B38 8208731 YP_003057502.1 CDS HELPY_0763 NC_012973.1 746315 755878 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16610017, 16579839, 16579837, 16552038, 16497614, 16489309; Product type pm : membrane component; vacuolating cytotoxin VacA-like complement(746315..755878) Helicobacter pylori B38 8207905 YP_003057503.1 CDS HELPY_0764 NC_012973.1 756045 756614 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(756045..756614) Helicobacter pylori B38 8207906 YP_003057504.1 CDS hefC NC_012973.1 756611 759700 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10639345, 7651136, 8987357, 8830678; Product type m : membrane component; Cytoplasmic pump proteins of the hefABC efflux system complement(756611..759700) Helicobacter pylori B38 8207907 YP_003057505.1 CDS hefB NC_012973.1 759710 760414 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10639345, 7651136, 8987357, 8830678; Product type m : membrane component; Membrane fusion protein of the hefABC efflux system complement(759710..760414) Helicobacter pylori B38 8208623 YP_003057506.1 CDS hefA NC_012973.1 760425 761858 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10639345, 7651136, 8987357, 8830678; Product type m : membrane component; outer-membrane protein of the hefABC efflux system complement(760425..761858) Helicobacter pylori B38 8208622 YP_003057507.1 CDS hemE NC_012973.1 761868 762887 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(761868..762887) Helicobacter pylori B38 8208621 YP_003057508.1 CDS HELPY_0769 NC_012973.1 762956 763573 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(762956..763573) Helicobacter pylori B38 8208628 YP_003057509.1 CDS magIII NC_012973.1 763570 764226 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10777493, 16468998; Product type e : enzyme; 3-methyladenine DNA glycosylase complement(763570..764226) Helicobacter pylori B38 8207908 YP_003057510.1 CDS flaA NC_012973.1 764354 765886 R FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A complement(764354..765886) Helicobacter pylori B38 8208748 YP_003057511.1 CDS HELPY_0772 NC_012973.1 766039 767820 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12504680; Product type t : transporter; ABC transporter permease and ATP-binding protein; membrane protein 766039..767820 Helicobacter pylori B38 8208511 YP_003057512.1 CDS HELPY_0773 NC_012973.1 767892 769193 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10456921, 8809743; Product type m : membrane component; methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) 767892..769193 Helicobacter pylori B38 8207909 YP_003057513.1 CDS bioF NC_012973.1 769216 770337 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11255013, 8763940, 3058702; Product type e : enzyme; 8-amino-7-oxononanoate synthase 769216..770337 Helicobacter pylori B38 8207910 YP_003057514.1 CDS pbpA NC_012973.1 770338 772317 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16684266, 12461003, 12069978, 11181392, 11083642, 10797079; Product type e : enzyme; Penicillin-binding protein 1 (peptidoglycan glycosyltransferase) 770338..772317 Helicobacter pylori B38 8208408 YP_003057515.1 CDS HELPY_0776 NC_012973.1 772320 772898 R Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein complement(772320..772898) Helicobacter pylori B38 8208841 YP_003057516.1 CDS HELPY_0778 NC_012973.1 773123 773245 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(773123..773245) Helicobacter pylori B38 8207911 YP_003057517.1 CDS HELPY_0779 NC_012973.1 773377 774849 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; disulfide oxidoreductase B (DsbB-like protein); membrane protein complement(773377..774849) Helicobacter pylori B38 8207912 YP_003057518.1 CDS HELPY_0780 NC_012973.1 774859 775023 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(774859..775023) Helicobacter pylori B38 8207913 YP_003057519.1 CDS HELPY_0781 NC_012973.1 775124 777058 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; type III restriction enzyme M protein complement(775124..777058) Helicobacter pylori B38 8207914 YP_003057520.1 CDS HELPY_0782 NC_012973.1 777055 780000 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type III restriction enzyme R protein complement(777055..780000) Helicobacter pylori B38 8207915 YP_003057521.1 CDS oorC NC_012973.1 780155 780715 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type e : enzyme; 2-oxoglutarate-acceptor oxidoreductase subunit OorC complement(780155..780715) Helicobacter pylori B38 8207916 YP_003057522.1 CDS oorB NC_012973.1 780715 781536 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type e : enzyme; 2-oxoglutarate-acceptor oxidoreductase subunit OorB complement(780715..781536) Helicobacter pylori B38 8208831 YP_003057523.1 CDS oorA NC_012973.1 781538 782665 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type e : enzyme; 2-oxoglutarate-acceptor oxidoreductase subunit OorA complement(781538..782665) Helicobacter pylori B38 8208830 YP_003057524.1 CDS oorD NC_012973.1 782665 783006 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9495749, 10809701, 8759844, 7608066; Product type c : carrier; 2-oxoglutarate-acceptor oxidoreductase subunit OorD complement(782665..783006) Helicobacter pylori B38 8208829 YP_003057525.1 CDS pabC NC_012973.1 783190 784179 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14745019, 11011151; Product type e : enzyme; Aminodeoxychorismate lyase complement(783190..784179) Helicobacter pylori B38 8208832 YP_003057526.1 CDS HELPY_0788 NC_012973.1 784097 787030 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 784097..787030 Helicobacter pylori B38 8208834 YP_003057527.1 CDS HELPY_0789 NC_012973.1 787032 787262 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 787032..787262 Helicobacter pylori B38 8207917 YP_003057528.1 CDS nth NC_012973.1 787265 787915 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12601164; Product type e : enzyme; endonuclease III 787265..787915 Helicobacter pylori B38 8207918 YP_003057529.1 CDS fliN NC_012973.1 787997 788368 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 787997..788368 Helicobacter pylori B38 8208808 YP_003057530.1 CDS HELPY_0792 NC_012973.1 788365 789246 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 788365..789246 Helicobacter pylori B38 8208541 YP_003057531.1 CDS HELPY_0793 NC_012973.1 789230 790204 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; siderophore-mediated iron transport protein 789230..790204 Helicobacter pylori B38 8207919 YP_003057532.1 CDS pyrC2 NC_012973.1 790208 791227 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 790208..791227 Helicobacter pylori B38 8207920 YP_003057533.1 CDS HELPY_0795 NC_012973.1 791245 792321 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 791245..792321 Helicobacter pylori B38 8208893 YP_003057534.1 CDS HELPY_0797 NC_012973.1 792328 792882 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 792328..792882 Helicobacter pylori B38 8207921 YP_003057535.1 CDS HELPY_0798 NC_012973.1 792888 794939 D Evidence 4b : Only in Helicobacter genus; hypothetical protein 792888..794939 Helicobacter pylori B38 8207922 YP_003057536.1 CDS folD NC_012973.1 795165 796037 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 795165..796037 Helicobacter pylori B38 8207923 YP_003057537.1 CDS lepB NC_012973.1 796037 796909 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16126156, 15546672, 12423785, 9194173; Product type e : enzyme; Signal peptidase I (SPase I) (Leader peptidase I) 796037..796909 Helicobacter pylori B38 8208550 YP_003057538.1 CDS HELPY_0801 NC_012973.1 796918 797616 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 796918..797616 Helicobacter pylori B38 8208728 YP_003057539.1 CDS rpi NC_012973.1 797649 798098 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 797649..798098 Helicobacter pylori B38 8207924 YP_003057540.1 CDS HELPY_0803 NC_012973.1 798165 798497 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 798165..798497 Helicobacter pylori B38 8208937 YP_003057541.1 CDS apt NC_012973.1 798555 799094 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 798555..799094 Helicobacter pylori B38 8207925 YP_003057542.1 CDS HELPY_0805 NC_012973.1 799109 799687 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 799109..799687 Helicobacter pylori B38 8208378 YP_003057543.1 CDS pepA NC_012973.1 799735 801225 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 799735..801225 Helicobacter pylori B38 8207926 YP_003057544.1 CDS gtp1 NC_012973.1 801227 802327 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 801227..802327 Helicobacter pylori B38 8208845 YP_003057545.1 CDS HELPY_0808 NC_012973.1 802462 803229 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 802462..803229 Helicobacter pylori B38 8208608 YP_003057546.1 CDS HELPY_0810 NC_012973.1 803297 804343 R Evidence 4c : Only in epsilon proteobacteria; Product type m : membrane component; hypothetical protein complement(803297..804343) Helicobacter pylori B38 8207927 YP_003057547.1 CDS dapF NC_012973.1 804458 805276 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 804458..805276 Helicobacter pylori B38 8207928 YP_003057548.1 CDS HELPY_0812 NC_012973.1 805389 806036 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type m : membrane component; hypothetical protein 805389..806036 Helicobacter pylori B38 8208452 YP_003057549.1 CDS HELPY_0813 NC_012973.1 806060 806305 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(806060..806305) Helicobacter pylori B38 8207929 YP_003057550.1 CDS HELPY_0814 NC_012973.1 806477 807727 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 806477..807727 Helicobacter pylori B38 8207930 YP_003057551.1 CDS rpsU NC_012973.1 807828 808040 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 807828..808040 Helicobacter pylori B38 8207931 YP_003057552.1 CDS fabG NC_012973.1 808079 808822 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 808079..808822 Helicobacter pylori B38 8208995 YP_003057553.1 CDS acpP NC_012973.1 809053 809289 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 809053..809289 Helicobacter pylori B38 8208495 YP_003057554.1 CDS fabF NC_012973.1 809393 810631 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 809393..810631 Helicobacter pylori B38 8208366 YP_003057555.1 CDS accA NC_012973.1 810654 811592 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 810654..811592 Helicobacter pylori B38 8208494 YP_003057556.1 CDS HELPY_0820 NC_012973.1 812061 812498 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 812061..812498 Helicobacter pylori B38 8208361 YP_003057557.1 CDS HELPY_0821 NC_012973.1 812568 813389 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(812568..813389) Helicobacter pylori B38 8207932 YP_003057558.1 CDS HELPY_0822 NC_012973.1 813386 814351 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(813386..814351) Helicobacter pylori B38 8207933 YP_003057559.1 CDS nshR NC_012973.1 814364 815047 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2401410; Product type e : enzyme; 23S rRNA methyltransferase complement(814364..815047) Helicobacter pylori B38 8207934 YP_003057560.1 CDS HELPY_0824 NC_012973.1 815060 815923 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methylase complement(815060..815923) Helicobacter pylori B38 8208806 YP_003057561.1 CDS rpmE NC_012973.1 815948 816151 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(815948..816151) Helicobacter pylori B38 8207935 YP_003057562.1 CDS rho NC_012973.1 816414 817730 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 816414..817730 Helicobacter pylori B38 8208964 YP_003057563.1 CDS murI NC_012973.1 817768 818535 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 817768..818535 Helicobacter pylori B38 8208916 YP_003057564.1 CDS HELPY_0828 NC_012973.1 818547 819401 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 818547..819401 Helicobacter pylori B38 8208790 YP_003057565.1 CDS HELPY_0829 NC_012973.1 819485 820477 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(819485..820477) Helicobacter pylori B38 8207936 YP_003057566.1 CDS era NC_012973.1 820474 821379 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(820474..821379) Helicobacter pylori B38 8207937 YP_003057567.1 CDS hslU NC_012973.1 821379 822710 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(821379..822710) Helicobacter pylori B38 8208486 YP_003057568.1 CDS hsp20 NC_012973.1 822710 823252 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(822710..823252) Helicobacter pylori B38 8208691 YP_003057569.1 CDS rplI NC_012973.1 823256 823705 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(823256..823705) Helicobacter pylori B38 8208692 YP_003057570.1 CDS HELPY_0835 NC_012973.1 824052 825281 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 complement(824052..825281) Helicobacter pylori B38 8207938 YP_003057571.1 CDS HELPY_0836 NC_012973.1 825268 825900 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 complement(825268..825900) Helicobacter pylori B38 8207939 YP_003057572.1 CDS HELPY_0837 NC_012973.1 825897 826082 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(825897..826082) Helicobacter pylori B38 8207940 YP_003057573.1 CDS HELPY_0838 NC_012973.1 826084 826302 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(826084..826302) Helicobacter pylori B38 8207941 YP_003057574.1 CDS glnA NC_012973.1 828425 829870 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11390701, 9573059, 1612427, 2574599; Product type e : enzyme; glutamine synthetase 828425..829870 Helicobacter pylori B38 8207943 YP_003057575.1 CDS HELPY_0841 NC_012973.1 829926 830072 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(829926..830072) Helicobacter pylori B38 8208588 YP_003057576.1 CDS lpp NC_012973.1 830097 830267 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10198012, 18227160; Product type lp : lipoprotein; urease-enhancing factor Lpp complement(830097..830267) Helicobacter pylori B38 8207944 YP_003057577.1 CDS dapB NC_012973.1 830698 831462 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(830698..831462) Helicobacter pylori B38 8208736 YP_003057578.1 CDS glcD NC_012973.1 831485 832864 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11283302, 8606183; Product type e : enzyme; glycolate oxidase subunit complement(831485..832864) Helicobacter pylori B38 8208449 YP_003057579.1 CDS HELPY_0845 NC_012973.1 832866 834215 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(832866..834215) Helicobacter pylori B38 8208584 YP_003057580.1 CDS HELPY_0846 NC_012973.1 834226 834864 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(834226..834864) Helicobacter pylori B38 8207945 YP_003057581.1 CDS HELPY_0847 NC_012973.1 834864 836084 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(834864..836084) Helicobacter pylori B38 8207946 YP_003057582.1 CDS HELPY_0850 NC_012973.1 837029 838021 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(837029..838021) Helicobacter pylori B38 8207949 YP_003057583.1 CDS gyrB NC_012973.1 838067 840388 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(838067..840388) Helicobacter pylori B38 8207950 YP_003057584.1 CDS dnaN NC_012973.1 840401 841525 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(840401..841525) Helicobacter pylori B38 8208613 YP_003057585.1 CDS HELPY_0855 NC_012973.1 842664 843992 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9779464, 8031825; Product type pt : transporter; sodium-and chloride-dependent transporter; membrane protein complement(842664..843992) Helicobacter pylori B38 8207952 YP_003057586.1 CDS HELPY_0856 NC_012973.1 844003 845331 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9779464, 8031825; Product type pt : transporter; sodium-and chloride-dependent transporter; membrane protein complement(844003..845331) Helicobacter pylori B38 8207953 YP_003057587.1 CDS HELPY_0857 NC_012973.1 845561 845962 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioesterase 845561..845962 Helicobacter pylori B38 8207954 YP_003057588.1 CDS HELPY_0858 NC_012973.1 845952 846212 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 845952..846212 Helicobacter pylori B38 8207955 YP_003057589.1 CDS murD NC_012973.1 846209 847477 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(846209..847477) Helicobacter pylori B38 8207956 YP_003057590.1 CDS mraY NC_012973.1 847479 848540 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(847479..848540) Helicobacter pylori B38 8208786 YP_003057591.1 CDS hpaA NC_012973.1 848666 849502 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16953581, 16428735, 15609408, 11855744, 9287032, 8487294, 7678592; Product type lp : lipoprotein; Neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin); signal peptide 848666..849502 Helicobacter pylori B38 8208778 YP_003057592.1 CDS rpmB NC_012973.1 849602 849790 D required for 70S ribosome assembly; 50S ribosomal protein L28 849602..849790 Helicobacter pylori B38 8208675 YP_003057593.1 CDS HELPY_0864 NC_012973.1 849973 851109 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; potassium channel protein 849973..851109 Helicobacter pylori B38 8208938 YP_003057594.1 CDS HELPY_0865 NC_012973.1 851464 852318 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(851464..852318) Helicobacter pylori B38 8207957 YP_003057595.1 CDS ruvA NC_012973.1 855214 855765 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(855214..855765) Helicobacter pylori B38 8207960 YP_003057596.1 CDS HELPY_0869 NC_012973.1 855791 857635 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(855791..857635) Helicobacter pylori B38 8208996 YP_003057597.1 CDS HELPY_0870 NC_012973.1 857801 859186 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11930024, 11274131, 2680969; Product type pf : factor; virulence factor MviN protein; membrane protein 857801..859186 Helicobacter pylori B38 8207961 YP_003057598.1 CDS cysS NC_012973.1 859187 860584 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 859187..860584 Helicobacter pylori B38 8207962 YP_003057599.1 CDS vacA NC_012973.1 860807 864745 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 18410539, 18201978, 18199531, 18039108, 17368441, 11560962, 11560948; Product type m : membrane component; Vacuolating cytotoxin 860807..864745 Helicobacter pylori B38 8208447 YP_003057600.1 CDS fecE NC_012973.1 864818 865585 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10802180, 1526456, 2254251; Product type t : transporter; ABC transporter ATP-binding protein; Iron(III) dicitrate ABC transporter ATP-binding protein complement(864818..865585) Helicobacter pylori B38 8209087 YP_003057601.1 CDS fecD NC_012973.1 865585 866565 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16484186, 14726233, 12896998, 12533448, 11123699, 1482271; Product type t : transporter; ABC transporter permease; Iron(III) dicitrate transport system permease protein FecD; membrane protein complement(865585..866565) Helicobacter pylori B38 8208504 YP_003057602.1 CDS HELPY_0875 NC_012973.1 866558 867412 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9139899; Product type pe : enzyme; short-chain oxidoreductase complement(866558..867412) Helicobacter pylori B38 8208503 YP_003057603.1 CDS HELPY_0876 NC_012973.1 867552 868076 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9139899; Product type pe : enzyme; acyl coenzyme A thioesterase 867552..868076 Helicobacter pylori B38 8207963 YP_003057604.1 CDS HELPY_0877 NC_012973.1 868436 868747 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(868436..868747) Helicobacter pylori B38 8207964 YP_003057605.1 CDS HELPY_0878 NC_012973.1 868825 869091 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(868825..869091) Helicobacter pylori B38 8207965 YP_003057606.1 CDS HELPY_0879 NC_012973.1 869072 869449 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(869072..869449) Helicobacter pylori B38 8207966 YP_003057607.1 CDS babA NC_012973.1 869745 871985 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16790815, 16322107, 15557006, 14762173, 11866522, 11160014, 9430586; Product type pm : membrane component; Adhesin complement(869745..871985) Helicobacter pylori B38 8207967 YP_003057609.1 CDS hypD NC_012973.1 873030 874142 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 16814778, 15504408, 11123699, 1482271; Product type f : factor; Hydrogenase expression/formation protein HypD complement(873030..874142) Helicobacter pylori B38 8208340 YP_003057610.1 CDS hypC NC_012973.1 874160 874396 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 15504408, 15491154, 10783387, 1482271; Product type f : factor; Hydrogenase expression/formation protein (HUPF/HYPC) complement(874160..874396) Helicobacter pylori B38 8208703 YP_003057611.1 CDS hypB NC_012973.1 874396 875124 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 14726233, 14521881, 1289699, 16807243, 16142921, 12533448, 11123699; Product type e : enzyme; Hydrogenase and urease maturation protein complement(874396..875124) Helicobacter pylori B38 8208702 YP_003057612.1 CDS HELPY_0885 NC_012973.1 875233 875358 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(875233..875358) Helicobacter pylori B38 8208701 YP_003057613.1 CDS HELPY_0886 NC_012973.1 875369 875668 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(875369..875668) Helicobacter pylori B38 8207968 YP_003057614.1 CDS pta NC_012973.1 876982 878538 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16678422, 16552088, 15062079, 15048838; Product type e : enzyme; phosphotransacetylase complement(876982..878538) Helicobacter pylori B38 8207971 YP_003057615.1 CDS HELPY_0890 NC_012973.1 878919 880457 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8631687; Product type pf : factor; flagellar control protein 878919..880457 Helicobacter pylori B38 8208883 YP_003057616.1 CDS flgD NC_012973.1 880508 881428 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 880508..881428 Helicobacter pylori B38 8207972 YP_003057617.1 CDS flgE NC_012973.1 881425 883242 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 881425..883242 Helicobacter pylori B38 8208518 YP_003057618.1 CDS HELPY_0893 NC_012973.1 883294 883875 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11226310; Product type pe : enzyme; type II restriction endonuclease Hpy8I 883294..883875 Helicobacter pylori B38 8208520 YP_003057619.1 CDS hpy8IM NC_012973.1 883897 885036 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11226310; Product type e : enzyme; type II m6A methylase 883897..885036 Helicobacter pylori B38 8207973 YP_003057620.1 CDS HELPY_0895 NC_012973.1 885040 887067 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16815905, 16442499, 15199167, 14757053, 10388562; Product type e : enzyme; ATP-dependent single-stranded DNA helicase 885040..887067 Helicobacter pylori B38 8208676 YP_003057621.1 CDS hopC NC_012973.1 887654 889207 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856, 12399485, 11925614, 7534278; Product type m : membrane component; outer membrane porin and adhesin HopC 887654..889207 Helicobacter pylori B38 8207974 YP_003057622.1 CDS hopB NC_012973.1 889229 890827 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12399485, 7534278, 16322107, 16173498, 15918181, 12454856, 11925614; Product type m : membrane component; outer membrane porin and adhesin HopB 889229..890827 Helicobacter pylori B38 8208650 YP_003057623.1 CDS HELPY_0900 NC_012973.1 891701 893245 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein complement(891701..893245) Helicobacter pylori B38 8208649 YP_003057624.1 CDS frpB2 NC_012973.1 893571 896012 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12704139, 12165031, 11886560, 16914236, 16797200, 11953376; Product type pt : transporter; Iron-regulated outer membrane protein complement(893571..896012) Helicobacter pylori B38 8207975 YP_003057625.1 CDS HELPY_0902 NC_012973.1 896196 896627 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(896196..896627) Helicobacter pylori B38 8208558 YP_003057626.1 CDS carB NC_012973.1 896632 899889 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(896632..899889) Helicobacter pylori B38 8207976 YP_003057627.1 CDS HELPY_0904 NC_012973.1 899987 900679 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein complement(899987..900679) Helicobacter pylori B38 8208890 YP_003057628.1 CDS gap1 NC_012973.1 900826 901824 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16523451; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase 900826..901824 Helicobacter pylori B38 8207977 YP_003057629.1 CDS HELPY_0906 NC_012973.1 901905 909479 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16610017, 16579839, 16579837, 16552038, 16497614, 16489309; Product type pf : factor; toxin-like outer membrane protein/vacuolating cytotoxin VacA 901905..909479 Helicobacter pylori B38 8208576 YP_003057630.1 CDS hopK NC_012973.1 909531 910625 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16220040, 16173498, 15918181, 12454856, 11211867, 9252185; Product type m : membrane component; outer membrane protein HopK 909531..910625 Helicobacter pylori B38 8207978 YP_003057631.1 CDS HELPY_0908 NC_012973.1 910693 910899 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16405343, 1732207, 7966298; Product type e : enzyme; tautomerase, DmpI-related protein complement(910693..910899) Helicobacter pylori B38 8208658 YP_003057632.1 CDS recR NC_012973.1 911056 911637 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 911056..911637 Helicobacter pylori B38 8207979 YP_003057633.1 CDS truD NC_012973.1 911634 912779 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 911634..912779 Helicobacter pylori B38 8208909 YP_003057634.1 CDS HELPY_0911 NC_012973.1 912766 913698 D metalloprotease; heat shock protein HtpX 912766..913698 Helicobacter pylori B38 8209059 YP_003057635.1 CDS folE NC_012973.1 913699 914241 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 913699..914241 Helicobacter pylori B38 8207980 YP_003057636.1 CDS ispA NC_012973.1 914257 915168 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15809342, 15236249, 8830250, 2089044, 2676985; Product type e : enzyme; geranyltranstransferase 914257..915168 Helicobacter pylori B38 8208551 YP_003057637.1 CDS surE NC_012973.1 915165 915968 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 915165..915968 Helicobacter pylori B38 8208715 YP_003057638.1 CDS HELPY_0915 NC_012973.1 915965 916624 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 915965..916624 Helicobacter pylori B38 8209021 YP_003057639.1 CDS HELPY_0916 NC_012973.1 916626 917228 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 916626..917228 Helicobacter pylori B38 8207981 YP_003057640.1 CDS HELPY_0917 NC_012973.1 917231 917986 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 917231..917986 Helicobacter pylori B38 8207982 YP_003057641.1 CDS HELPY_0918 NC_012973.1 918083 918568 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 918083..918568 Helicobacter pylori B38 8207983 YP_003057642.1 CDS HELPY_0924 NC_012973.1 921987 922376 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(921987..922376) Helicobacter pylori B38 8207989 YP_003057643.1 CDS HELPY_0925 NC_012973.1 922444 923133 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter permease complement(922444..923133) Helicobacter pylori B38 8207990 YP_003057644.1 CDS HELPY_0926 NC_012973.1 923141 923902 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC-type transport system, periplasmic binding protein complement(923141..923902) Helicobacter pylori B38 8207991 YP_003057645.1 CDS alr NC_012973.1 923970 925103 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15683232, 9063881, 16310730; Product type e : enzyme; alanine racemase complement(923970..925103) Helicobacter pylori B38 8207992 YP_003057646.1 CDS HELPY_0928 NC_012973.1 925110 926462 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1447975, 1400476, 8031825; Product type pt : transporter; amino acid transporter; membrane protein complement(925110..926462) Helicobacter pylori B38 8208373 YP_003057647.1 CDS HELPY_0929 NC_012973.1 926503 927735 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9457858, 7906689; Product type pe : enzyme; D-amino acid dehydrogenase complement(926503..927735) Helicobacter pylori B38 8207993 YP_003057648.1 CDS HELPY_0930 NC_012973.1 927758 928135 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10368157, 10557275; Product type pr : regulator; translation initiation inhibitor complement(927758..928135) Helicobacter pylori B38 8207994 YP_003057649.1 CDS HELPY_0931 NC_012973.1 929062 930543 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15228539, 16021482, 9190799; Product type pt : transporter; cation antiporter; membrane protein 929062..930543 Helicobacter pylori B38 8208357 YP_003057650.1 CDS HELPY_0932 NC_012973.1 930869 931231 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 930869..931231 Helicobacter pylori B38 8207996 YP_003057651.1 CDS HELPY_0933 NC_012973.1 931437 931592 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(931437..931592) Helicobacter pylori B38 8207997 YP_003057652.1 CDS HELPY_0934 NC_012973.1 931635 932648 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(931635..932648) Helicobacter pylori B38 8207998 YP_003057653.1 CDS HELPY_0935 NC_012973.1 932658 933110 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(932658..933110) Helicobacter pylori B38 8207999 YP_003057654.1 CDS accD NC_012973.1 933124 933993 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(933124..933993) Helicobacter pylori B38 8208000 YP_003057655.1 CDS HELPY_0937 NC_012973.1 934074 934688 D Evidence 4c : Only in epsilon proteobacteria; recombination protein RecO 934074..934688 Helicobacter pylori B38 8208364 YP_003057656.1 CDS HELPY_0938 NC_012973.1 934699 935355 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7538190; Product type pf : factor; competence/damage-inducible protein CinA 934699..935355 Helicobacter pylori B38 8208001 YP_003057657.1 CDS HELPY_0939 NC_012973.1 935358 935924 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(935358..935924) Helicobacter pylori B38 8208002 YP_003057658.1 CDS rdxA NC_012973.1 935989 936621 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16426819, 15904482, 15856372, 15496391, 15361078, 12738391, 12648728; Product type e : enzyme; NAD(P)H-dependent nitroreductase complement(935989..936621) Helicobacter pylori B38 8208003 YP_003057659.1 CDS lgt NC_012973.1 936618 937472 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(936618..937472) Helicobacter pylori B38 8208904 YP_003057660.1 CDS rluC NC_012973.1 937482 938210 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15078091, 9660827, 9843401; Product type e : enzyme; Pseudouridine synthase (RNA-uridine isomerase) (RNA pseudouridylate synthase) complement(937482..938210) Helicobacter pylori B38 8208730 YP_003057661.1 CDS waaA NC_012973.1 938229 939410 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(938229..939410) Helicobacter pylori B38 8208925 YP_003057662.1 CDS HELPY_0944 NC_012973.1 939411 940190 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(939411..940190) Helicobacter pylori B38 8209089 YP_003057663.1 CDS HELPY_0945 NC_012973.1 940200 940931 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(940200..940931) Helicobacter pylori B38 8208004 YP_003057664.1 CDS glyQ NC_012973.1 940933 941829 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(940933..941829) Helicobacter pylori B38 8208005 YP_003057665.1 CDS gpsA NC_012973.1 941843 942781 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(941843..942781) Helicobacter pylori B38 8208594 YP_003057666.1 CDS acpP2 NC_012973.1 942913 943209 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15113832, 14536035; Product type c : carrier; Acyl carrier protein (ACP) complement(942913..943209) Helicobacter pylori B38 8208602 YP_003057667.1 CDS HELPY_0949 NC_012973.1 943277 945214 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATPase complement(943277..945214) Helicobacter pylori B38 8208367 YP_003057668.1 CDS HELPY_0955 NC_012973.1 949605 949886 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(949605..949886) Helicobacter pylori B38 8208011 YP_003057669.1 CDS HELPY_0956 NC_012973.1 949902 952964 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426358, 11023484, 10473554, 9371429, 8991852, 8829543; Product type pt : transporter; cobalt-zinc-cadmium resistance protein, CzcA family; membrane protein complement(949902..952964) Helicobacter pylori B38 8208012 YP_003057670.1 CDS HELPY_0957 NC_012973.1 952961 954040 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426358, 9371429, 8991852; Product type pt : transporter; cobalt-zinc-cadmium resistance protein, CzcB family complement(952961..954040) Helicobacter pylori B38 8208013 YP_003057671.1 CDS HELPY_0958 NC_012973.1 954037 955335 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(954037..955335) Helicobacter pylori B38 8208014 YP_003057672.1 CDS glyS NC_012973.1 955325 957430 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(955325..957430) Helicobacter pylori B38 8208015 YP_003057673.1 CDS HELPY_0960 NC_012973.1 957543 958661 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 957543..958661 Helicobacter pylori B38 8208595 YP_003057674.1 CDS gpmI NC_012973.1 958674 960149 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 958674..960149 Helicobacter pylori B38 8208016 YP_003057675.1 CDS gatC NC_012973.1 960164 960445 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 960164..960445 Helicobacter pylori B38 8208600 YP_003057676.1 CDS bioA NC_012973.1 960541 961860 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(960541..961860) Helicobacter pylori B38 8208579 YP_003057677.1 CDS HELPY_0964 NC_012973.1 961990 963453 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16267292, 9670013; Product type pe : enzyme; pedidyl-prolyl cis-trans ismerase D 961990..963453 Helicobacter pylori B38 8208404 YP_003057678.1 CDS ftsA NC_012973.1 963468 964949 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12626683, 16159787, 11847116, 11053380, 1400163; Product type cp : cell process; Cell division protein ftsA 963468..964949 Helicobacter pylori B38 8208017 YP_003057679.1 CDS ftsZ NC_012973.1 965074 966237 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 965074..966237 Helicobacter pylori B38 8208562 YP_003057680.1 CDS HELPY_0971 NC_012973.1 967112 967303 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(967112..967303) Helicobacter pylori B38 8208567 YP_003057681.1 CDS HELPY_0973 NC_012973.1 967380 967676 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7674922; Product type pe : enzyme; metallopeptidase 967380..967676 Helicobacter pylori B38 8208018 YP_003057682.1 CDS HELPY_0974 NC_012973.1 967669 967923 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10856643, 3021756; Product type pe : enzyme; exonuclease VII, large subunit 967669..967923 Helicobacter pylori B38 8208019 YP_003057683.1 CDS HELPY_0976 NC_012973.1 968424 969248 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15063854, 14671322, 12626684, 12080120, 10202137, 2546007; Product type pt : transporter; small-conductance mechanosensitive channel; membrane protein 968424..969248 Helicobacter pylori B38 8208321 YP_003057684.1 CDS HELPY_0977 NC_012973.1 969535 969750 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 969535..969750 Helicobacter pylori B38 8208021 YP_003057685.1 CDS HELPY_0987 NC_012973.1 976664 976948 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(976664..976948) Helicobacter pylori B38 8208031 YP_003057686.1 CDS HELPY_0988 NC_012973.1 977059 977193 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(977059..977193) Helicobacter pylori B38 8208032 YP_003057687.1 CDS HELPY_0989 NC_012973.1 977190 980792 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(977190..980792) Helicobacter pylori B38 8208033 YP_003057688.1 CDS HELPY_0990 NC_012973.1 980786 982135 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; serine/threonine kinase complement(980786..982135) Helicobacter pylori B38 8208034 YP_003057689.1 CDS HELPY_0993 NC_012973.1 982809 983111 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(982809..983111) Helicobacter pylori B38 8208037 YP_003057690.1 CDS HELPY_0994 NC_012973.1 983229 983873 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(983229..983873) Helicobacter pylori B38 8208038 YP_003057691.1 CDS HELPY_0996 NC_012973.1 984215 984358 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 984215..984358 Helicobacter pylori B38 8208039 YP_003057692.1 CDS HELPY_1000 NC_012973.1 988415 988642 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 988415..988642 Helicobacter pylori B38 8208318 YP_003057693.1 CDS HELPY_1001 NC_012973.1 988695 990410 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 988695..990410 Helicobacter pylori B38 8208041 YP_003057694.1 CDS HELPY_1002 NC_012973.1 990482 991810 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 990482..991810 Helicobacter pylori B38 8208042 YP_003057695.1 CDS HELPY_1003 NC_012973.1 991777 993636 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 991777..993636 Helicobacter pylori B38 8208043 YP_003057696.1 CDS speA NC_012973.1 994801 996648 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(994801..996648) Helicobacter pylori B38 8208046 YP_003057697.1 CDS HELPY_1007 NC_012973.1 996663 997832 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7961465; Product type pe : enzyme; polysaccharide biosynthesis protein complement(996663..997832) Helicobacter pylori B38 8209016 YP_003057698.1 CDS HELPY_1008 NC_012973.1 997837 998265 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(997837..998265) Helicobacter pylori B38 8208047 YP_003057699.1 CDS HELPY_1009 NC_012973.1 998280 999065 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(998280..999065) Helicobacter pylori B38 8208048 YP_003057700.1 CDS HELPY_1010 NC_012973.1 999069 1000076 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(999069..1000076) Helicobacter pylori B38 8208049 YP_003057701.1 CDS metS NC_012973.1 1000076 1002028 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1000076..1002028) Helicobacter pylori B38 8208050 YP_003057702.1 CDS cfa NC_012973.1 1002197 1003366 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20353464, 9882672, 8022273, 93075691; Product type e : enzyme; cyclopropane-fatty-acyl-phospholipid synthase 1002197..1003366 Helicobacter pylori B38 8208755 YP_003057703.1 CDS HELPY_1013 NC_012973.1 1003376 1005247 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1003376..1005247) Helicobacter pylori B38 8208418 YP_003057704.1 CDS HELPY_1014 NC_012973.1 1006470 1007219 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97431527, 93139035, 96042077, 93253769; Product type ps : structure; neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin); signal peptide complement(1006470..1007219) Helicobacter pylori B38 8208336 YP_003057705.1 CDS guaA NC_012973.1 1007303 1008829 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1007303..1008829) Helicobacter pylori B38 8208052 YP_003057706.1 CDS HELPY_1016 NC_012973.1 1008840 1009331 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1008840..1009331) Helicobacter pylori B38 8208609 YP_003057707.1 CDS bisC NC_012973.1 1009505 1011895 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15601707, 8919859, 2180922, 9242907, 8890912; Product type e : enzyme; biotin sulfoxide reductase complement(1009505..1011895) Helicobacter pylori B38 8208053 YP_003057708.1 CDS HELPY_1019 NC_012973.1 1011999 1012589 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1011999..1012589) Helicobacter pylori B38 8208410 YP_003057709.1 CDS HELPY_1020 NC_012973.1 1012615 1013937 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; cysteine desulfurase complement(1012615..1013937) Helicobacter pylori B38 8208054 YP_003057710.1 CDS HELPY_1021 NC_012973.1 1013956 1014270 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15703176, 1472710; Product type pe : enzyme; hydrolase complement(1013956..1014270) Helicobacter pylori B38 8208055 YP_003057711.1 CDS pheS NC_012973.1 1014351 1015337 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1014351..1015337 Helicobacter pylori B38 8208056 YP_003057712.1 CDS pheT NC_012973.1 1015337 1017631 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1015337..1017631 Helicobacter pylori B38 8208858 YP_003057713.1 CDS aroA NC_012973.1 1017647 1018936 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1017647..1018936 Helicobacter pylori B38 8208859 YP_003057714.1 CDS ispH NC_012973.1 1018926 1019750 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1018926..1019750 Helicobacter pylori B38 8208380 YP_003057715.1 CDS rpsA NC_012973.1 1019871 1021541 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1019871..1021541 Helicobacter pylori B38 8208720 YP_003057716.1 CDS HELPY_1027 NC_012973.1 1021570 1022121 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1021570..1022121 Helicobacter pylori B38 8208975 YP_003057717.1 CDS serA NC_012973.1 1022137 1023711 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1022137..1023711 Helicobacter pylori B38 8208057 YP_003057718.1 CDS ubiD NC_012973.1 1023721 1025571 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15979273, 12799002, 11029449, 782527; Product type e : enzyme; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1023721..1025571 Helicobacter pylori B38 8209010 YP_003057719.1 CDS HELPY_1030 NC_012973.1 1025581 1026249 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1025581..1026249 Helicobacter pylori B38 8209071 YP_003057720.1 CDS HELPY_1031 NC_012973.1 1026251 1027009 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1026251..1027009 Helicobacter pylori B38 8208058 YP_003057721.1 CDS cheV3 NC_012973.1 1027013 1027948 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16207913, 11535789, 16369945, 8809743, 8169224, 8169223; Product type r : regulator; Chemotaxis protein CheV 1027013..1027948 Helicobacter pylori B38 8208059 YP_003057722.1 CDS cheA NC_012973.1 1028004 1030451 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16879644, 16207913, 15664919, 10722597, 9724541; Product type e : enzyme; Chemotaxis protein cheA 1028004..1030451 Helicobacter pylori B38 8208422 YP_003057723.1 CDS cheW NC_012973.1 1030448 1030945 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16207913, 11535789, 16369945, 1326408, 8809743, 8456299; Product type r : regulator; Chemotaxis protein CheW 1030448..1030945 Helicobacter pylori B38 8208419 YP_003057724.1 CDS tpx NC_012973.1 1031205 1031705 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11744405, 15158282, 11673441, 9457886, 7523254; Product type e : enzyme; thiol peroxidase complement(1031205..1031705) Helicobacter pylori B38 8208423 YP_003057725.1 CDS sodB NC_012973.1 1031928 1032569 D [Fe]; Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15901691, 16416177, 10675591, 7515365, 8225605; Product type e : enzyme; Superoxide dismutase 1031928..1032569 Helicobacter pylori B38 8209048 YP_003057726.1 CDS HELPY_1037 NC_012973.1 1032621 1033352 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1032621..1033352 Helicobacter pylori B38 8209015 YP_003057727.1 CDS priA NC_012973.1 1033386 1035245 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1033386..1035245) Helicobacter pylori B38 8208060 YP_003057728.1 CDS HELPY_1039 NC_012973.1 1035230 1035466 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1035230..1035466) Helicobacter pylori B38 8208875 YP_003057729.1 CDS HELPY_1040 NC_012973.1 1035479 1035709 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1035479..1035709) Helicobacter pylori B38 8208061 YP_003057730.1 CDS HELPY_1041 NC_012973.1 1035888 1036634 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1035888..1036634 Helicobacter pylori B38 8208062 YP_003057731.1 CDS HELPY_1042 NC_012973.1 1036674 1037198 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1036674..1037198) Helicobacter pylori B38 8208063 YP_003057732.1 CDS HELPY_1043 NC_012973.1 1037379 1038602 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metalloprotease; membrane protein 1037379..1038602 Helicobacter pylori B38 8208064 YP_003057733.1 CDS hemG NC_012973.1 1038599 1039423 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15629922, 15223314, 11805295, 10690633, 10220893, 7883187; Product type e : enzyme; Modification methylase HemK 1038599..1039423 Helicobacter pylori B38 8208065 YP_003057734.1 CDS gdhA NC_012973.1 1039495 1040841 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1039495..1040841 Helicobacter pylori B38 8208629 YP_003057735.1 CDS futA NC_012973.1 1040855 1042183 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16477004, 15058985, 10496917; Product type e : enzyme; Alpha1,3-fucosyltransferase complement(1040855..1042183) Helicobacter pylori B38 8208580 YP_003057736.1 CDS ccsA NC_012973.1 1042193 1045003 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16629661, 8617725; Product type f : factor; Cytochrome c biogenesis protein; membrane protein complement(1042193..1045003) Helicobacter pylori B38 8208571 YP_003057737.1 CDS HELPY_1048 NC_012973.1 1045012 1045683 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1045012..1045683) Helicobacter pylori B38 8208415 YP_003057738.1 CDS hemH NC_012973.1 1045756 1046763 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1045756..1046763) Helicobacter pylori B38 8208066 YP_003057739.1 CDS HELPY_1050 NC_012973.1 1046819 1047250 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1046819..1047250 Helicobacter pylori B38 8208630 YP_003057740.1 CDS HELPY_1051 NC_012973.1 1047251 1047931 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1047251..1047931 Helicobacter pylori B38 8208067 YP_003057741.1 CDS HELPY_1052 NC_012973.1 1048024 1050141 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1048024..1050141) Helicobacter pylori B38 8208068 YP_003057742.1 CDS dcd NC_012973.1 1050300 1050866 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(1050300..1050866) Helicobacter pylori B38 8208069 YP_003057743.1 CDS accB NC_012973.1 1050996 1051478 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11390406, 11157970, 10542197; Product type e : enzyme; biotin carboxyl carrier protein of acetyl-CoA carboxylase 1050996..1051478 Helicobacter pylori B38 8208453 YP_003057744.1 CDS accC NC_012973.1 1051484 1052851 D biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1051484..1052851 Helicobacter pylori B38 8208362 YP_003057745.1 CDS HELPY_1056 NC_012973.1 1052944 1053906 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17921292, 17346936, 11226310; Product type pe : enzyme; adenine methyltransferase 1052944..1053906 Helicobacter pylori B38 8208363 YP_003057746.1 CDS HELPY_1057 NC_012973.1 1053903 1054454 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17346936, 16217547, 14711809, 12490707, 12426350, 12034832, 11956101; Product type pe : enzyme; type II restriction endonuclease 1053903..1054454 Helicobacter pylori B38 8208070 YP_003057747.1 CDS HELPY_1058 NC_012973.1 1054547 1055155 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1054547..1055155 Helicobacter pylori B38 8208071 YP_003057748.1 CDS pseC NC_012973.1 1055152 1056288 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16421095; Product type e : enzyme; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 1055152..1056288 Helicobacter pylori B38 8208072 YP_003057749.1 CDS nrdF NC_012973.1 1056599 1057624 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1056599..1057624 Helicobacter pylori B38 8208334 YP_003057750.1 CDS pcm NC_012973.1 1057634 1058263 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1057634..1058263 Helicobacter pylori B38 8208805 YP_003057751.1 CDS HELPY_1062 NC_012973.1 1058274 1059311 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1058274..1059311 Helicobacter pylori B38 8208842 YP_003057752.1 CDS truA NC_012973.1 1059312 1060040 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1059312..1060040 Helicobacter pylori B38 8208073 YP_003057753.1 CDS galE NC_012973.1 1060034 1061068 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14597172, 11425718, 11119535, 9708982; Product type e : enzyme; UDP-glucose 4-epimerase(Galactowaldenase) (UDP-galactose 4-epimerase) complement(1060034..1061068) Helicobacter pylori B38 8209058 YP_003057754.1 CDS HELPY_1065 NC_012973.1 1061783 1063318 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1061783..1063318 Helicobacter pylori B38 8208359 YP_003057755.1 CDS HELPY_1066 NC_012973.1 1063336 1064088 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase 1063336..1064088 Helicobacter pylori B38 8208074 YP_003057756.1 CDS hcpC NC_012973.1 1064295 1065167 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16460007, 16040986, 15223324, 11777911, 99369890, 10748053; Product type cp : cell process; Cysteine-rich protein C complement(1064295..1065167) Helicobacter pylori B38 8208075 YP_003057757.1 CDS eda NC_012973.1 1065242 1065862 R [4-hydroxy-2-oxoglutarate aldolase (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxy-phosphogluconate aldolase (phospho-2-dehydro-3-deoxygluconate aldolase) (phospho-2-keto-3-deoxygluconate aldolase) (2-keto-3-deoxy-6-phosphogluconate aldolase) (KDPG-aldolase)]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15659677, 12889025; Product type e : enzyme; multifunctional KHG/KDPG aldolase complement(1065242..1065862) Helicobacter pylori B38 8208615 YP_003057758.1 CDS edd NC_012973.1 1065881 1067707 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1065881..1067707) Helicobacter pylori B38 8208481 YP_003057759.1 CDS zwf NC_012973.1 1067774 1069051 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1067774..1069051 Helicobacter pylori B38 8208482 YP_003057760.1 CDS pgl NC_012973.1 1069062 1069745 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15766779; Product type pe : enzyme; 6-phosphogluconolactonase 1069062..1069745 Helicobacter pylori B38 8209095 YP_003057761.1 CDS glk NC_012973.1 1069732 1070742 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1069732..1070742 Helicobacter pylori B38 8208855 YP_003057762.1 CDS HELPY_1073 NC_012973.1 1070903 1071949 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; zinc-containing alcohol dehydrogenase 1070903..1071949 Helicobacter pylori B38 8208585 YP_003057763.1 CDS HELPY_1074 NC_012973.1 1071961 1073256 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1624461; Product type pe : enzyme; lipopolysaccharide 1,3-galactosyltransferase complement(1071961..1073256) Helicobacter pylori B38 8208076 YP_003057764.1 CDS HELPY_1075 NC_012973.1 1073435 1074742 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1073435..1074742 Helicobacter pylori B38 8208077 YP_003057765.1 CDS HELPY_1076 NC_012973.1 1074749 1075411 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein HorH complement(1074749..1075411) Helicobacter pylori B38 8208078 YP_003057766.1 CDS porG NC_012973.1 1075689 1076249 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; pyruvate flavodoxin oxidoreductase subunit gamma 1075689..1076249 Helicobacter pylori B38 8208079 YP_003057767.1 CDS porD NC_012973.1 1076265 1076657 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; pyruvate flavodoxin oxidoreductase subunit delta 1076265..1076657 Helicobacter pylori B38 8208866 YP_003057768.1 CDS porA NC_012973.1 1076667 1077890 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; pyruvate flavodoxin oxidoreductase subunit alpha 1076667..1077890 Helicobacter pylori B38 8208865 YP_003057769.1 CDS porB NC_012973.1 1077903 1078847 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 7608066, 9495749; Product type e : enzyme; Pyruvate synthase subunit porB 1077903..1078847 Helicobacter pylori B38 8208863 YP_003057770.1 CDS purB NC_012973.1 1078957 1080279 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1078957..1080279 Helicobacter pylori B38 8208864 YP_003057771.1 CDS HELPY_1083 NC_012973.1 1080350 1081183 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein 1080350..1081183 Helicobacter pylori B38 8208886 YP_003057772.1 CDS uvrB NC_012973.1 1081194 1083170 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1081194..1083170) Helicobacter pylori B38 8208080 YP_003057773.1 CDS HELPY_1085 NC_012973.1 1083211 1083861 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1083211..1083861) Helicobacter pylori B38 8209084 YP_003057774.1 CDS hcpX NC_012973.1 1087149 1087919 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10748053, 11777911, 9317022, 9596777; Product type pe : enzyme; hypothetical protein complement(1087149..1087919) Helicobacter pylori B38 8208083 YP_003057775.1 CDS ggt NC_012973.1 1088186 1089889 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15378780, 11349094, 10200957; Product type e : enzyme; gamma-glutamyltranspeptidase complement(1088186..1089889) Helicobacter pylori B38 8208620 YP_003057776.1 CDS flgK NC_012973.1 1090105 1091925 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(1090105..1091925) Helicobacter pylori B38 8208581 YP_003057777.1 CDS HELPY_1092 NC_012973.1 1091927 1092361 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1091927..1092361) Helicobacter pylori B38 8208525 YP_003057778.1 CDS hpyAVIIIM NC_012973.1 1092493 1093449 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14711809, 12034832, 11703661, 11226310, 11133936; Product type e : enzyme; type II cytosine specific DNA methyltransferase complement(1092493..1093449) Helicobacter pylori B38 8208084 YP_003057779.1 CDS flgM NC_012973.1 1093590 1093820 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11985711, 11489132; Product type f : factor; Anti-sigma 28 factor complement(1093590..1093820) Helicobacter pylori B38 8208683 YP_003057780.1 CDS HELPY_1095 NC_012973.1 1093857 1094063 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1093857..1094063) Helicobacter pylori B38 8208527 YP_003057781.1 CDS slyD NC_012973.1 1094095 1094652 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15569666, 12100551; Product type pe : enzyme; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD complement(1094095..1094652) Helicobacter pylori B38 8208085 YP_003057782.1 CDS HELPY_1097 NC_012973.1 1094639 1095634 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1094639..1095634) Helicobacter pylori B38 8209013 YP_003057783.1 CDS palA NC_012973.1 1095642 1096181 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10515919, 8763621; Product type lp : lipoprotein; peptidoglycan-associated lipoprotein ; petide signal complement(1095642..1096181) Helicobacter pylori B38 8208086 YP_003057784.1 CDS tolB NC_012973.1 1096248 1097501 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(1096248..1097501) Helicobacter pylori B38 8208835 YP_003057785.1 CDS HELPY_1100 NC_012973.1 1097498 1098319 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1097498..1098319) Helicobacter pylori B38 8209044 YP_003057786.1 CDS exbD1 NC_012973.1 1098338 1098739 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; biopolymer transport protein ExbD/TolR complement(1098338..1098739) Helicobacter pylori B38 8208087 YP_003057787.1 CDS exbB1 NC_012973.1 1098792 1099361 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; Biopolymer transport ExbB protein; membrane protein complement(1098792..1099361) Helicobacter pylori B38 8208490 YP_003057788.1 CDS atpC NC_012973.1 1099372 1099746 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1099372..1099746) Helicobacter pylori B38 8208487 YP_003057789.1 CDS atpD NC_012973.1 1099753 1101162 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1099753..1101162) Helicobacter pylori B38 8208395 YP_003057790.1 CDS atpG NC_012973.1 1101184 1102089 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1101184..1102089) Helicobacter pylori B38 8208396 YP_003057791.1 CDS atpA NC_012973.1 1102104 1103615 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1102104..1103615) Helicobacter pylori B38 8208399 YP_003057792.1 CDS atpH NC_012973.1 1103638 1104180 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1103638..1104180) Helicobacter pylori B38 8208393 YP_003057793.1 CDS atpF NC_012973.1 1104181 1104696 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1104181..1104696) Helicobacter pylori B38 8208400 YP_003057794.1 CDS atpX NC_012973.1 1104700 1105134 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' complement(1104700..1105134) Helicobacter pylori B38 8208398 YP_003057795.1 CDS HELPY_1110 NC_012973.1 1105245 1106120 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10619014, 9506522; Product type pr : regulator; plasmid replication-partition related protein complement(1105245..1106120) Helicobacter pylori B38 8208401 YP_003057796.1 CDS HELPY_1111 NC_012973.1 1106120 1106914 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522501, 11042157, 9701812; Product type pr : regulator; SpoOJ regulator complement(1106120..1106914) Helicobacter pylori B38 8208088 YP_003057797.1 CDS birA NC_012973.1 1106917 1107555 R [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase(Biotin--protein ligase)]; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(1106917..1107555) Helicobacter pylori B38 8208089 YP_003057798.1 CDS fmt NC_012973.1 1107564 1108475 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1107564..1108475) Helicobacter pylori B38 8208409 YP_003057799.1 CDS HELPY_1114 NC_012973.1 1108499 1110772 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1108499..1110772) Helicobacter pylori B38 8208547 YP_003057800.1 CDS HELPY_1115 NC_012973.1 1110818 1112119 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1110818..1112119) Helicobacter pylori B38 8208090 YP_003057801.1 CDS HELPY_1116 NC_012973.1 1112390 1112806 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1112390..1112806 Helicobacter pylori B38 8208091 YP_003057802.1 CDS HELPY_1119 NC_012973.1 1115376 1116167 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1115376..1116167) Helicobacter pylori B38 8208316 YP_003057803.1 CDS rplS NC_012973.1 1116818 1117174 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1116818..1117174) Helicobacter pylori B38 8208093 YP_003057804.1 CDS trmD NC_012973.1 1117196 1117885 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1117196..1117885) Helicobacter pylori B38 8208955 YP_003057805.1 CDS rimM NC_012973.1 1117886 1118440 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1117886..1118440) Helicobacter pylori B38 8209049 YP_003057806.1 CDS HELPY_1124 NC_012973.1 1118441 1118788 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; RNA-binding protein complement(1118441..1118788) Helicobacter pylori B38 8208923 YP_003057807.1 CDS rpsP NC_012973.1 1118805 1119035 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1118805..1119035) Helicobacter pylori B38 8208094 YP_003057808.1 CDS ffh NC_012973.1 1119109 1120455 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11735405, 16343944, 16299512, 16005894; Product type f : factor; Signal recognition particle protein (SRP) complement(1119109..1120455) Helicobacter pylori B38 8208990 YP_003057809.1 CDS valS NC_012973.1 1120471 1123095 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1120471..1123095) Helicobacter pylori B38 8208506 YP_003057810.1 CDS HELPY_1128 NC_012973.1 1123226 1123633 D binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1123226..1123633 Helicobacter pylori B38 8209088 YP_003057811.1 CDS murG NC_012973.1 1123644 1124705 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 1123644..1124705 Helicobacter pylori B38 8208095 YP_003057812.1 CDS hopI NC_012973.1 1124814 1126898 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopI 1124814..1126898 Helicobacter pylori B38 8208789 YP_003057813.1 CDS hopL NC_012973.1 1126921 1130598 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopL 1126921..1130598 Helicobacter pylori B38 8208656 YP_003057814.1 CDS proC NC_012973.1 1130611 1131384 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1130611..1131384 Helicobacter pylori B38 8208660 YP_003057815.1 CDS HELPY_1133 NC_012973.1 1131411 1131944 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1656497, 6284712; Product type ph : phenotype; cAMP-induced cell filamentation protein 1131411..1131944 Helicobacter pylori B38 8208877 YP_003057816.1 CDS HELPY_1134 NC_012973.1 1132190 1132612 R Evidence 4 : Homologs of previously reported genes of unknown function; metalloprotease complement(1132190..1132612) Helicobacter pylori B38 8208096 YP_003057817.1 CDS fldA NC_012973.1 1132666 1133160 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(1132666..1133160) Helicobacter pylori B38 8208097 YP_003057818.1 CDS HELPY_1136 NC_012973.1 1133252 1133866 R Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein complement(1133252..1133866) Helicobacter pylori B38 8208515 YP_003057819.1 CDS HELPY_1137 NC_012973.1 1133967 1134158 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2536685; Product type pt : transporter; cation transport subunit for cbb3-type oxidase 1133967..1134158 Helicobacter pylori B38 8208098 YP_003057820.1 CDS trxB NC_012973.1 1134184 1135155 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16597971, 16427080, 15358361, 15063614; Product type pe : enzyme; thioredoxin reductase 1134184..1135155 Helicobacter pylori B38 8208099 YP_003057821.1 CDS HELPY_1139 NC_012973.1 1135162 1136322 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9529885; Product type pt : transporter; permease, MFS superfamily; membrane protein complement(1135162..1136322) Helicobacter pylori B38 8209062 YP_003057822.1 CDS pgi NC_012973.1 1136386 1138023 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1136386..1138023 Helicobacter pylori B38 8208100 YP_003057823.1 CDS hofH NC_012973.1 1138329 1139744 D Evidence 1a : Function experimentally demonstrated in the studied strain; Product type m : membrane component; outer membrane protein HofH 1138329..1139744 Helicobacter pylori B38 8208853 YP_003057824.1 CDS cstA NC_012973.1 1140097 1142160 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17526692, 12867454, 91162636, 2521622, 1848300; Product type t : transporter; Carbon starvation protein A; membrane protein complement(1140097..1142160) Helicobacter pylori B38 8208642 YP_003057825.1 CDS HELPY_1143 NC_012973.1 1142371 1143024 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3027504, 15795228; Product type t : transporter; ABC transporter permease; amino-acid transporter GlnP1 1142371..1143024 Helicobacter pylori B38 8208444 YP_003057826.1 CDS HELPY_1144 NC_012973.1 1143027 1143698 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3027504, 15795228; Product type t : transporter; ABC transporter permease; amino-acid transporter GlnP2 1143027..1143698 Helicobacter pylori B38 8208101 YP_003057827.1 CDS HELPY_1145 NC_012973.1 1143700 1144446 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15795228, 12010975, 8360165; Product type t : transporter; ABC transporter ATP-binding protein; glutamate/aspartate transport protein GlnQ 1143700..1144446 Helicobacter pylori B38 8208102 YP_003057828.1 CDS HELPY_1146 NC_012973.1 1144465 1145328 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12010975, 9142743, 3027504; Product type t : transporter; ABC transporter substrate-binding protein 1144465..1145328 Helicobacter pylori B38 8208103 YP_003057829.1 CDS HELPY_1147 NC_012973.1 1145450 1146001 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1145450..1146001 Helicobacter pylori B38 8208104 YP_003057830.1 CDS HELPY_1148 NC_012973.1 1146223 1147446 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15050034, 8661924; Product type t : transporter; glucose/galactose transporter GluP complement(1146223..1147446) Helicobacter pylori B38 8208105 YP_003057831.1 CDS HELPY_1149 NC_012973.1 1147575 1148882 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease; membrane protein complement(1147575..1148882) Helicobacter pylori B38 8208106 YP_003057832.1 CDS hopQ NC_012973.1 1149344 1151236 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16102915, 15939494, 14742532, 12454143, 16322107, 16173498, 15918181; Product type m : membrane component; outer membrane protein HopQ complement(1149344..1151236) Helicobacter pylori B38 8208107 YP_003057833.1 CDS deoD NC_012973.1 1152057 1152758 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511068, 12571059, 11444965, 11437593, 3299264; Product type e : enzyme; Purine nucleoside phosphorylase DeoD-type (PNP) complement(1152057..1152758) Helicobacter pylori B38 8208664 YP_003057834.1 CDS deoB NC_012973.1 1152755 1153996 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1152755..1153996) Helicobacter pylori B38 8208459 YP_003057835.1 CDS HELPY_1153 NC_012973.1 1154008 1155264 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16177292, 15678184, 11065368, 8853292; Product type pt : transporter; transport protein, Concentrative Nucleoside transporter (CNT) family; membrane protein complement(1154008..1155264) Helicobacter pylori B38 8208458 YP_003057836.1 CDS HELPY_1154 NC_012973.1 1155580 1156911 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug-efflux transporter; membrane protein 1155580..1156911 Helicobacter pylori B38 8208333 YP_003057837.1 CDS HELPY_1155 NC_012973.1 1156932 1157693 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12012333; Product type pe : enzyme; PP-loop family ATPase 1156932..1157693 Helicobacter pylori B38 8208109 YP_003057838.1 CDS HELPY_1156 NC_012973.1 1157702 1158853 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; NA+/H+ antiporter complement(1157702..1158853) Helicobacter pylori B38 8208110 YP_003057839.1 CDS HELPY_1157 NC_012973.1 1158879 1160258 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug resistance protein; membrane protein complement(1158879..1160258) Helicobacter pylori B38 8208111 YP_003057840.1 CDS HELPY_1158 NC_012973.1 1160419 1161594 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20138160; Product type pt : transporter; sugar efflux transporter complement(1160419..1161594) Helicobacter pylori B38 8208112 YP_003057841.1 CDS cah NC_012973.1 1161866 1162609 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16539401, 16459077, 16202223, 9811652, 8673298; Product type e : enzyme; Alpha-carbonic anhydrase 1161866..1162609 Helicobacter pylori B38 8208113 YP_003057842.1 CDS HELPY_1160 NC_012973.1 1162839 1164008 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1162839..1164008) Helicobacter pylori B38 8208412 YP_003057843.1 CDS asd NC_012973.1 1164420 1165460 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12071715, 15300892, 15752328, 15313252, 12071715; Product type e : enzyme; Aspartate-semialdehyde dehydrogenase complement(1164420..1165460) Helicobacter pylori B38 8208114 YP_003057844.1 CDS hisS NC_012973.1 1165447 1166775 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1165447..1166775) Helicobacter pylori B38 8208387 YP_003057845.1 CDS rfaF NC_012973.1 1166837 1167886 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12798993, 11208792, 9916106, 9831648; Product type e : enzyme; ADP-heptose--LPS-heptosyltransferase II 1166837..1167886 Helicobacter pylori B38 8208634 YP_003057846.1 CDS HELPY_1164 NC_012973.1 1168069 1168344 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1168069..1168344) Helicobacter pylori B38 8208913 YP_003057847.1 CDS HELPY_1166 NC_012973.1 1168563 1169552 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1447221, 10884227; Product type pe : enzyme; aldo-keto reductase 1168563..1169552 Helicobacter pylori B38 8208115 YP_003057848.1 CDS fusA NC_012973.1 1170114 1172192 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1170114..1172192) Helicobacter pylori B38 8208116 YP_003057849.1 CDS rpsG NC_012973.1 1172204 1172671 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1172204..1172671) Helicobacter pylori B38 8208570 YP_003057850.1 CDS rpsL NC_012973.1 1172687 1173094 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1172687..1173094) Helicobacter pylori B38 8208981 YP_003057851.1 CDS rpoBC NC_012973.1 1173183 1181855 R [DNA-directed RNA polymerase subunit beta (transcriptase subunit beta) (RNA polymerase subunit beta); DNA-directed RNA polymerase subunit beta' (transcriptase subunit beta') (RNA polymerase subunit beta'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' complement(1173183..1181855) Helicobacter pylori B38 8208986 YP_003057852.1 CDS rplL NC_012973.1 1182078 1182455 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1182078..1182455) Helicobacter pylori B38 8208971 YP_003057853.1 CDS rplJ NC_012973.1 1182501 1182995 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1182501..1182995) Helicobacter pylori B38 8208948 YP_003057854.1 CDS rplA NC_012973.1 1183104 1183808 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1183104..1183808) Helicobacter pylori B38 8208946 YP_003057855.1 CDS rplK NC_012973.1 1183853 1184278 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1183853..1184278) Helicobacter pylori B38 8208939 YP_003057856.1 CDS nusG NC_012973.1 1184296 1184826 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1184296..1184826) Helicobacter pylori B38 8208947 YP_003057857.1 CDS secE NC_012973.1 1184853 1185032 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1184853..1185032) Helicobacter pylori B38 8208825 YP_003057858.1 CDS rpmG NC_012973.1 1185289 1185447 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1185289..1185447) Helicobacter pylori B38 8208332 YP_003057859.1 CDS tuf NC_012973.1 1185481 1186680 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1185481..1186680) Helicobacter pylori B38 8208966 YP_003057860.1 CDS HELPY_1180 NC_012973.1 1187381 1189117 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter ATP-binding protein and permease; membrane protein 1187381..1189117 Helicobacter pylori B38 8208328 YP_003057861.1 CDS HELPY_1181 NC_012973.1 1189128 1189796 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8702766; Product type e : enzyme; haloacid dehalogenase complement(1189128..1189796) Helicobacter pylori B38 8208117 YP_003057862.1 CDS hpyAIM NC_012973.1 1189997 1190986 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 2277628, 7607512, 7663118, 20576144, 98012982, 21126955; Product type e : enzyme; type II adenosine specific DNA methyltransferase M.HpyAI complement(1189997..1190986) Helicobacter pylori B38 8208118 YP_003057863.1 CDS cysE NC_012973.1 1191751 1192266 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10672045, 11395450, 16481326, 15516574, 10930739; Product type e : enzyme; Serine acetyltransferase (SAT) complement(1191751..1192266) Helicobacter pylori B38 8208121 YP_003057864.1 CDS atpE NC_012973.1 1192864 1193181 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1192864..1193181) Helicobacter pylori B38 8208326 YP_003057865.1 CDS pnp NC_012973.1 1193314 1195380 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8825779, 16428774, 16299002, 16282984, 16275923, 16237005; Product type e : enzyme; polynucleotide phosphorylase/polyadenylase complement(1193314..1195380) Helicobacter pylori B38 8208397 YP_003057866.1 CDS HELPY_1190 NC_012973.1 1195383 1196087 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphoribosyltransferase complement(1195383..1196087) Helicobacter pylori B38 8208861 YP_003057867.1 CDS imp NC_012973.1 1196101 1198362 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 95110156, 12207697; Product type m : membrane component; organic solvent tolerance protein complement(1196101..1198362) Helicobacter pylori B38 8208122 YP_003057868.1 CDS HELPY_1193 NC_012973.1 1198365 1198844 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1198365..1198844) Helicobacter pylori B38 8208711 YP_003057869.1 CDS purD NC_012973.1 1198893 1200167 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 98047359, 15271960, 9683487; Product type e : enzyme; phosphoribosylamine--glycine ligase complement(1198893..1200167) Helicobacter pylori B38 8208123 YP_003057870.1 CDS HELPY_1195 NC_012973.1 1200480 1201166 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 98254124, 99449617, 16399363, 16400872; Product type t : transporter; ABC transporter ATP-binding protein complement(1200480..1201166) Helicobacter pylori B38 8208887 YP_003057871.1 CDS uppS NC_012973.1 1201160 1201864 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase complement(1201160..1201864) Helicobacter pylori B38 8208124 YP_003057872.1 CDS HELPY_1197 NC_012973.1 1201904 1204744 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; D-lactate dehydrogenase complement(1201904..1204744) Helicobacter pylori B38 8209074 YP_003057873.1 CDS HELPY_1198 NC_012973.1 1204816 1205148 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1204816..1205148 Helicobacter pylori B38 8208125 YP_003057874.1 CDS hemD NC_012973.1 1205151 1205831 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1205151..1205831 Helicobacter pylori B38 8208126 YP_003057875.1 CDS crcB NC_012973.1 1205879 1206271 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1205879..1206271 Helicobacter pylori B38 8208627 YP_003057876.1 CDS hemN NC_012973.1 1206317 1207354 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1206317..1207354) Helicobacter pylori B38 8208442 YP_003057877.1 CDS HELPY_1202 NC_012973.1 1207450 1207740 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; cytochrome c553 1207450..1207740 Helicobacter pylori B38 8208633 YP_003057878.1 CDS HELPY_1203 NC_012973.1 1207901 1208368 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1207901..1208368 Helicobacter pylori B38 8208127 YP_003057879.1 CDS lysC NC_012973.1 1208370 1209587 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1208370..1209587 Helicobacter pylori B38 8208128 YP_003057880.1 CDS hobA NC_012973.1 1209584 1210126 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17645450, 17683397; Product type f : factor; DnaA initiator-associating factor for replication initiation HobA 1209584..1210126 Helicobacter pylori B38 8208746 YP_003057881.1 CDS holB NC_012973.1 1210123 1210779 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1210123..1210779 Helicobacter pylori B38 8208635 YP_003057882.1 CDS folP NC_012973.1 1210776 1211918 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15554970, 16553853, 16503987, 15554970, 10817704, 10471557, 8586264; Product type e : enzyme; Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase) 1210776..1211918 Helicobacter pylori B38 8208644 YP_003057883.1 CDS HELPY_1208 NC_012973.1 1212007 1212468 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1212007..1212468) Helicobacter pylori B38 8208553 YP_003057884.1 CDS HELPY_1209 NC_012973.1 1212859 1213755 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1212859..1213755 Helicobacter pylori B38 8208129 YP_003057885.1 CDS HELPY_1210 NC_012973.1 1213759 1215006 D Evidence 4c : Only in epsilon proteobacteria; Product type pm : membrane component; hypothetical protein 1213759..1215006 Helicobacter pylori B38 8208130 YP_003057886.1 CDS HELPY_1211 NC_012973.1 1215085 1215636 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1215085..1215636 Helicobacter pylori B38 8208131 YP_003057887.1 CDS carA NC_012973.1 1215636 1216763 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1215636..1216763 Helicobacter pylori B38 8208132 YP_003057888.1 CDS amiF NC_012973.1 1216929 1217933 D formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 1216929..1217933 Helicobacter pylori B38 8208413 YP_003057889.1 CDS HELPY_1214 NC_012973.1 1218145 1218264 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1218145..1218264) Helicobacter pylori B38 8208376 YP_003057890.1 CDS HELPY_1215 NC_012973.1 1218378 1218950 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1218378..1218950) Helicobacter pylori B38 8208133 YP_003057891.1 CDS alaS NC_012973.1 1218952 1221495 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1218952..1221495) Helicobacter pylori B38 8208134 YP_003057892.1 CDS HELPY_1217 NC_012973.1 1221614 1221844 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1221614..1221844 Helicobacter pylori B38 8208371 YP_003057893.1 CDS rpsR NC_012973.1 1225450 1225707 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1225450..1225707) Helicobacter pylori B38 8208137 YP_003057894.1 CDS ssb NC_012973.1 1225730 1226275 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1225730..1226275) Helicobacter pylori B38 8208992 YP_003057895.1 CDS rpsF NC_012973.1 1226285 1226713 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1226285..1226713) Helicobacter pylori B38 8209020 YP_003057896.1 CDS holA NC_012973.1 1227058 1228080 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(1227058..1228080) Helicobacter pylori B38 8208980 YP_003057897.1 CDS rnr NC_012973.1 1228070 1230007 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16563345, 15664199, 11948193, 9603904, 1400189; Product type e : enzyme; ribonuclease R complement(1228070..1230007) Helicobacter pylori B38 8208643 YP_003057898.1 CDS aroE NC_012973.1 1230007 1230798 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1230007..1230798) Helicobacter pylori B38 8208933 YP_003057899.1 CDS HELPY_1226 NC_012973.1 1230806 1231396 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1230806..1231396) Helicobacter pylori B38 8208383 YP_003057900.1 CDS HELPY_1227 NC_012973.1 1231405 1232451 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter permease complement(1231405..1232451) Helicobacter pylori B38 8208138 YP_003057901.1 CDS HELPY_1228 NC_012973.1 1232448 1234229 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter substrate-binding protein complement(1232448..1234229) Helicobacter pylori B38 8208139 YP_003057902.1 CDS trpS NC_012973.1 1234230 1235210 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(1234230..1235210) Helicobacter pylori B38 8208140 YP_003057903.1 CDS bioC NC_012973.1 1235281 1236018 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; biotin biosynthesis protein BioC complement(1235281..1236018) Helicobacter pylori B38 8209057 YP_003057904.1 CDS secG NC_012973.1 1236135 1236740 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15039361, 14659543, 9184221, 16677301, 16428426, 16154141, 15546659; Product type t : transporter; preprotein translocase subunit SecG 1236135..1236740 Helicobacter pylori B38 8208406 YP_003057905.1 CDS frr NC_012973.1 1236740 1237297 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1236740..1237297 Helicobacter pylori B38 8209007 YP_003057906.1 CDS pyrE NC_012973.1 1237301 1237906 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1237301..1237906 Helicobacter pylori B38 8208560 YP_003057907.1 CDS HELPY_1234 NC_012973.1 1237896 1238360 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1237896..1238360 Helicobacter pylori B38 8208895 YP_003057908.1 CDS HELPY_1235 NC_012973.1 1238357 1239046 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7498786, 10381378; Product type pe : enzyme; NAD+-dependent deacetylase, Sir2 family 1238357..1239046 Helicobacter pylori B38 8208141 YP_003057909.1 CDS nuoA NC_012973.1 1239154 1239555 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A 1239154..1239555 Helicobacter pylori B38 8208142 YP_003057910.1 CDS nuoB NC_012973.1 1239555 1240034 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1239555..1240034 Helicobacter pylori B38 8208809 YP_003057911.1 CDS nuoC NC_012973.1 1240034 1240831 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C 1240034..1240831 Helicobacter pylori B38 8208810 YP_003057912.1 CDS nuoD NC_012973.1 1240833 1242062 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1240833..1242062 Helicobacter pylori B38 8208811 YP_003057913.1 CDS nuoE NC_012973.1 1242059 1242289 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15922336; Product type e : enzyme; NADH-ubiquinone oxidoreductase subunit E 1242059..1242289 Helicobacter pylori B38 8208812 YP_003057914.1 CDS nuoF NC_012973.1 1242292 1243278 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15922336, 15922336; Product type e : enzyme; NADH-ubiquinone oxidoreductase subunit F 1242292..1243278 Helicobacter pylori B38 8208813 YP_003057915.1 CDS nuoG NC_012973.1 1243275 1245836 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1243275..1245836 Helicobacter pylori B38 8208814 YP_003057916.1 CDS nuoH NC_012973.1 1245833 1246822 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1245833..1246822 Helicobacter pylori B38 8208815 YP_003057917.1 CDS nuoI NC_012973.1 1246833 1247495 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1246833..1247495 Helicobacter pylori B38 8208816 YP_003057918.1 CDS nuoJ NC_012973.1 1247488 1248036 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1247488..1248036 Helicobacter pylori B38 8208817 YP_003057919.1 CDS nuoK NC_012973.1 1248033 1248335 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1248033..1248335 Helicobacter pylori B38 8208818 YP_003057920.1 CDS nuoL NC_012973.1 1248338 1250176 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1248338..1250176 Helicobacter pylori B38 8208819 YP_003057921.1 CDS nuoM NC_012973.1 1250180 1251718 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1250180..1251718 Helicobacter pylori B38 8208820 YP_003057922.1 CDS nuoN NC_012973.1 1251705 1253177 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1251705..1253177 Helicobacter pylori B38 8208821 YP_003057923.1 CDS HELPY_1250 NC_012973.1 1253167 1255572 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7715450; Product type pf : factor; paralysed flagella protein PflA 1253167..1255572 Helicobacter pylori B38 8208822 YP_003057924.1 CDS HELPY_1252 NC_012973.1 1255574 1256950 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1712067; Product type pe : enzyme; phosphomannomutase (PMM) 1255574..1256950 Helicobacter pylori B38 8208143 YP_003057925.1 CDS HELPY_1253 NC_012973.1 1257243 1257530 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1257243..1257530 Helicobacter pylori B38 8208144 YP_003057926.1 CDS trpA NC_012973.1 1257772 1258560 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1257772..1258560) Helicobacter pylori B38 8208145 YP_003057927.1 CDS trpB NC_012973.1 1258557 1259738 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1258557..1259738) Helicobacter pylori B38 8209051 YP_003057928.1 CDS trpCF NC_012973.1 1259739 1261097 R [Indole-3-glycerol phosphate synthase, N-terminal (IGPS); N-(5-phosphoribosyl)anthranilate isomerase, C-terminal (PRAI)]; monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1259739..1261097) Helicobacter pylori B38 8209052 YP_003057929.1 CDS trpD NC_012973.1 1261090 1262097 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1261090..1262097) Helicobacter pylori B38 8209053 YP_003057930.1 CDS trpG NC_012973.1 1262094 1262678 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1262094..1262678) Helicobacter pylori B38 8209054 YP_003057931.1 CDS trpE NC_012973.1 1262675 1264177 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1262675..1264177) Helicobacter pylori B38 8209056 YP_003057932.1 CDS HELPY_1260 NC_012973.1 1264411 1265466 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyltransferase complement(1264411..1265466) Helicobacter pylori B38 8209055 YP_003057933.1 CDS HELPY_1261 NC_012973.1 1265534 1266271 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11395461, 10760156; Product type pm : membrane component; acid phosphatase lipoprotein complement(1265534..1266271) Helicobacter pylori B38 8208146 YP_003057934.1 CDS HELPY_1262 NC_012973.1 1266395 1266943 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1266395..1266943 Helicobacter pylori B38 8208147 YP_003057935.1 CDS HELPY_1263 NC_012973.1 1267007 1267660 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8662211, 1898926; Product type r : regulator; transcriptional regulator complement(1267007..1267660) Helicobacter pylori B38 8208148 YP_003057936.1 CDS coaX NC_012973.1 1268352 1268711 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16699190, 15795230, 7929447; Product type e : enzyme; Pantothenate kinase (type III) 1268352..1268711 Helicobacter pylori B38 8208149 YP_003057937.1 CDS HELPY_1265 NC_012973.1 1268751 1269245 D Evidence 4a : Only in Helicobacter pylori; Product type pm : membrane component; hypothetical protein 1268751..1269245 Helicobacter pylori B38 8208431 YP_003057938.1 CDS HELPY_1266 NC_012973.1 1269431 1270093 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15968063, 2546921, 2198247, 1991724; Product type pt : transporter; nicotinamide mononucleotide transporter PnuC 1269431..1270093 Helicobacter pylori B38 8208322 YP_003057939.1 CDS HELPY_1267 NC_012973.1 1270090 1270695 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16728979, 15150256, 11435118; Product type pe : enzyme; thiamine pyrophosphokinase 1270090..1270695 Helicobacter pylori B38 8208151 YP_003057940.1 CDS rplQ NC_012973.1 1271340 1271690 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1271340..1271690) Helicobacter pylori B38 8208152 YP_003057941.1 CDS rpoA NC_012973.1 1271690 1272724 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1271690..1272724) Helicobacter pylori B38 8208953 YP_003057942.1 CDS rpsD NC_012973.1 1272736 1273362 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1272736..1273362) Helicobacter pylori B38 8208970 YP_003057943.1 CDS rpsK NC_012973.1 1273372 1273767 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1273372..1273767) Helicobacter pylori B38 8208978 YP_003057944.1 CDS rpsM NC_012973.1 1273790 1274152 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1273790..1274152) Helicobacter pylori B38 8208985 YP_003057945.1 CDS rpmJ NC_012973.1 1274156 1274269 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(1274156..1274269) Helicobacter pylori B38 8208987 YP_003057946.1 CDS infA NC_012973.1 1274347 1274565 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1274347..1274565) Helicobacter pylori B38 8208968 YP_003057947.1 CDS map NC_012973.1 1274565 1275326 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(1274565..1275326) Helicobacter pylori B38 8208712 YP_003057948.1 CDS secY NC_012973.1 1275326 1276588 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1275326..1276588) Helicobacter pylori B38 8208750 YP_003057949.1 CDS rplO NC_012973.1 1276628 1277029 R late assembly protein; 50S ribosomal protein L15 complement(1276628..1277029) Helicobacter pylori B38 8209008 YP_003057950.1 CDS rpsE NC_012973.1 1277049 1277510 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1277049..1277510) Helicobacter pylori B38 8208951 YP_003057951.1 CDS rplR NC_012973.1 1277507 1277866 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1277507..1277866) Helicobacter pylori B38 8208979 YP_003057952.1 CDS rplF NC_012973.1 1277877 1278413 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1277877..1278413) Helicobacter pylori B38 8208954 YP_003057953.1 CDS rpsH NC_012973.1 1278424 1278819 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1278424..1278819) Helicobacter pylori B38 8208944 YP_003057954.1 CDS rpsN NC_012973.1 1278829 1279014 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 complement(1278829..1279014) Helicobacter pylori B38 8208982 YP_003057955.1 CDS rplE NC_012973.1 1279024 1279569 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1279024..1279569) Helicobacter pylori B38 8208988 YP_003057956.1 CDS rplX NC_012973.1 1279582 1279803 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1279582..1279803) Helicobacter pylori B38 8208943 YP_003057957.1 CDS rplN NC_012973.1 1279803 1280171 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1279803..1280171) Helicobacter pylori B38 8208960 YP_003057958.1 CDS rpsQ NC_012973.1 1280174 1280434 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1280174..1280434) Helicobacter pylori B38 8208950 YP_003057959.1 CDS rpmC NC_012973.1 1280448 1280660 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1280448..1280660) Helicobacter pylori B38 8208991 YP_003057960.1 CDS rplP NC_012973.1 1280635 1281060 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1280635..1281060) Helicobacter pylori B38 8208963 YP_003057961.1 CDS rpsC NC_012973.1 1281063 1281767 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1281063..1281767) Helicobacter pylori B38 8208952 YP_003057962.1 CDS rplV NC_012973.1 1281771 1282139 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1281771..1282139) Helicobacter pylori B38 8208977 YP_003057963.1 CDS rpsS NC_012973.1 1282149 1282430 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1282149..1282430) Helicobacter pylori B38 8208958 YP_003057964.1 CDS rplB NC_012973.1 1282442 1283272 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1282442..1283272) Helicobacter pylori B38 8208993 YP_003057965.1 CDS rplW NC_012973.1 1283288 1283569 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1283288..1283569) Helicobacter pylori B38 8208940 YP_003057966.1 CDS rplD NC_012973.1 1283573 1284220 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1283573..1284220) Helicobacter pylori B38 8208959 YP_003057967.1 CDS rplC NC_012973.1 1284255 1284830 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1284255..1284830) Helicobacter pylori B38 8208942 YP_003057968.1 CDS rpsJ NC_012973.1 1284867 1285181 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1284867..1285181) Helicobacter pylori B38 8208941 YP_003057969.1 CDS HELPY_1297 NC_012973.1 1285344 1286477 D Evidence 4b : Only in Helicobacter genus; hypothetical protein 1285344..1286477 Helicobacter pylori B38 8208984 YP_003057970.1 CDS HELPY_1298 NC_012973.1 1286743 1287321 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1286743..1287321 Helicobacter pylori B38 8208153 YP_003057971.1 CDS rnhB NC_012973.1 1287295 1287909 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1287295..1287909) Helicobacter pylori B38 8208154 YP_003057972.1 CDS HELPY_1300 NC_012973.1 1287940 1288191 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1287940..1288191) Helicobacter pylori B38 8208930 YP_003057973.1 CDS fumC NC_012973.1 1288214 1289605 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1288214..1289605) Helicobacter pylori B38 8208155 YP_003057974.1 CDS HELPY_1302 NC_012973.1 1289780 1290157 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1289780..1290157 Helicobacter pylori B38 8208568 YP_003057975.1 CDS HELPY_1303 NC_012973.1 1290162 1291400 D Evidence 4b : Only in Helicobacter genus; hypothetical protein 1290162..1291400 Helicobacter pylori B38 8208156 YP_003057976.1 CDS HELPY_1304 NC_012973.1 1291397 1292422 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12877469, 11023484, 12877469, 10473554; Product type pt : transporter; cobalt-zinc-cadmium resistance protein CzcB 1291397..1292422 Helicobacter pylori B38 8208157 YP_003057977.1 CDS HELPY_1305 NC_012973.1 1292423 1295530 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12877469, 11023484, 12877469, 10473554; Product type pt : transporter; heavy metal efflux pump CzcA 1292423..1295530 Helicobacter pylori B38 8208158 YP_003057978.1 CDS HELPY_1306 NC_012973.1 1295511 1295867 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9287000, 11162545; Product type pt : transporter; branched-chain amino acid transport protein AzlD; membrane protein complement(1295511..1295867) Helicobacter pylori B38 8208159 YP_003057979.1 CDS HELPY_1307 NC_012973.1 1295861 1296547 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9287000, 11162545; Product type pt : transporter; branched-chain amino acid transport protein AzlC; membrane protein complement(1295861..1296547) Helicobacter pylori B38 8208160 YP_003057980.1 CDS dnaJ2 NC_012973.1 1296558 1297667 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(1296558..1297667) Helicobacter pylori B38 8208161 YP_003057981.1 CDS HELPY_1309 NC_012973.1 1297792 1298934 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1297792..1298934 Helicobacter pylori B38 8208467 YP_003057982.1 CDS mnmA NC_012973.1 1298978 1300006 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1298978..1300006) Helicobacter pylori B38 8208162 YP_003057983.1 CDS HELPY_1311 NC_012973.1 1300146 1300907 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1300146..1300907 Helicobacter pylori B38 8209050 YP_003057984.1 CDS HELPY_1312 NC_012973.1 1300904 1301419 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10894752, 11704676; Product type pe : enzyme; nicotinate-nucleotide adenyltransferase complement(1300904..1301419) Helicobacter pylori B38 8208163 YP_003057985.1 CDS nikR NC_012973.1 1301412 1301858 R Inhibits transcription at high concentrations of nickel; nickel responsive regulator complement(1301412..1301858) Helicobacter pylori B38 8208164 YP_003057986.1 CDS exbB2 NC_012973.1 1302192 1302629 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12890020, 16321934, 15819630, 2670903, 9643536, 981166, 7642501, 9159515; Product type t : transporter; Biopolymer transport accessory protein; membrane protein 1302192..1302629 Helicobacter pylori B38 8208802 YP_003057987.1 CDS exbD2 NC_012973.1 1302626 1303015 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12890020, 16321934, 15819630, 9643536, 9811664, 9371459, 7642501; Product type t : transporter; Biopolymer transport protein ExbD 1302626..1303015 Helicobacter pylori B38 8208488 YP_003057988.1 CDS tonB2 NC_012973.1 1302981 1303832 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10931324; Product type t : transporter; Siderophore-mediated iron transport protein 1302981..1303832 Helicobacter pylori B38 8208491 YP_003057989.1 CDS hopM NC_012973.1 1304027 1306117 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856; Product type m : membrane component; outer membrane protein HopM 1304027..1306117 Helicobacter pylori B38 8209045 YP_003057990.1 CDS HELPY_1318 NC_012973.1 1306256 1306984 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11016400, 10069007; Product type pt : transporter; transporter; membrane protein complement(1306256..1306984) Helicobacter pylori B38 8208662 YP_003057991.1 CDS corA NC_012973.1 1306991 1307947 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12065537, 16857941, 16720382, 16598263, 16179994, 15516579, 15231793; Product type t : transporter; Magnesium, nickel and cobalt transport protein CorA complement(1306991..1307947) Helicobacter pylori B38 8208165 YP_003057992.1 CDS pgk NC_012973.1 1307963 1309171 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1307963..1309171) Helicobacter pylori B38 8208440 YP_003057993.1 CDS HELPY_1322 NC_012973.1 1309187 1310179 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15250823, 16527864; Product type pe : enzyme; glyceraldehyde-3-phosphate dehydrogenase complement(1309187..1310179) Helicobacter pylori B38 8208854 YP_003057994.1 CDS ung NC_012973.1 1310261 1310962 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1310261..1310962) Helicobacter pylori B38 8208166 YP_003057995.1 CDS HELPY_1324 NC_012973.1 1310959 1311660 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16151217, 10361297, 8748025; Product type pe : enzyme; 1-acylglycerol-3-phosphate O-acyltransferase complement(1310959..1311660) Helicobacter pylori B38 8209073 YP_003057996.1 CDS HELPY_1325 NC_012973.1 1311647 1312762 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1311647..1312762) Helicobacter pylori B38 8208167 YP_003057997.1 CDS HELPY_1326 NC_012973.1 1312825 1314204 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7845208, 10966643, 9141685, 8576225, 7499412, 1856173; Product type e : enzyme; Carboxyl-terminal protease, S41A family complement(1312825..1314204) Helicobacter pylori B38 8208168 YP_003057998.1 CDS HELPY_1331 NC_012973.1 1316041 1316298 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1316041..1316298 Helicobacter pylori B38 8208173 YP_003057999.1 CDS HELPY_1332 NC_012973.1 1316300 1316485 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1316300..1316485 Helicobacter pylori B38 8208174 YP_003058000.1 CDS HELPY_1333 NC_012973.1 1316482 1317114 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 1316482..1317114 Helicobacter pylori B38 8208175 YP_003058001.1 CDS HELPY_1334 NC_012973.1 1317101 1318330 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 1317101..1318330 Helicobacter pylori B38 8208176 YP_003058002.1 CDS HELPY_1338 NC_012973.1 1319610 1321046 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphorylase 1319610..1321046 Helicobacter pylori B38 8208179 YP_003058003.1 CDS hypAIVR NC_012973.1 1321452 1322324 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12034832, 11703661, 11166995, 11133936, 11226310; Product type e : enzyme; type II restriction endonuclease complement(1321452..1322324) Helicobacter pylori B38 8208181 YP_003058004.1 CDS hpyAIVM NC_012973.1 1322324 1323403 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12034832, 11703661, 11166995, 11133936, 11226310; Product type e : enzyme; type II m6A methylase complement(1322324..1323403) Helicobacter pylori B38 8208700 YP_003058005.1 CDS nadC NC_012973.1 1327167 1327988 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(1327167..1327988) Helicobacter pylori B38 8208184 YP_003058006.1 CDS nadA NC_012973.1 1327988 1328998 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(1327988..1328998) Helicobacter pylori B38 8208794 YP_003058007.1 CDS psd NC_012973.1 1328988 1329791 R [Contains: phosphatidylserine decarboxylase alpha chain; phosphatidylserine decarboxylase beta chain]; catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase complement(1328988..1329791) Helicobacter pylori B38 8208793 YP_003058008.1 CDS HELPY_1348 NC_012973.1 1329785 1330291 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1329785..1330291) Helicobacter pylori B38 8208880 YP_003058009.1 CDS HELPY_1349 NC_012973.1 1330304 1330798 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1330304..1330798) Helicobacter pylori B38 8208185 YP_003058010.1 CDS ubiA NC_012973.1 1330791 1331675 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase complement(1330791..1331675) Helicobacter pylori B38 8208186 YP_003058011.1 CDS HELPY_1351 NC_012973.1 1331702 1332931 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; DNA competence protein; membrane protein complement(1331702..1332931) Helicobacter pylori B38 8209070 YP_003058012.1 CDS dnaB NC_012973.1 1333012 1334472 R unwinds double stranded DNA; replicative DNA helicase complement(1333012..1334472) Helicobacter pylori B38 8208187 YP_003058013.1 CDS HELPY_1353 NC_012973.1 1334483 1335883 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1334483..1335883) Helicobacter pylori B38 8208463 YP_003058014.1 CDS HELPY_1354 NC_012973.1 1335886 1337004 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1335886..1337004) Helicobacter pylori B38 8208188 YP_003058015.1 CDS HELPY_1355 NC_012973.1 1337054 1337695 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type r : regulator; transcriptional regulatory protein complement(1337054..1337695) Helicobacter pylori B38 8208189 YP_003058016.1 CDS HELPY_1358 NC_012973.1 1340244 1343150 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type III restriction enzyme R protein 1340244..1343150 Helicobacter pylori B38 8208192 YP_003058017.1 CDS mreC NC_012973.1 1343207 1343953 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(1343207..1343953) Helicobacter pylori B38 8208193 YP_003058018.1 CDS mreB NC_012973.1 1343957 1345000 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(1343957..1345000) Helicobacter pylori B38 8208780 YP_003058019.1 CDS clpX NC_012973.1 1345042 1346388 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1345042..1346388) Helicobacter pylori B38 8208779 YP_003058020.1 CDS lpxA NC_012973.1 1346390 1347202 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1346390..1347202) Helicobacter pylori B38 8208429 YP_003058021.1 CDS fabZ NC_012973.1 1347205 1347684 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1347205..1347684) Helicobacter pylori B38 8208738 YP_003058022.1 CDS HELPY_1364 NC_012973.1 1347866 1348267 R binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW complement(1347866..1348267) Helicobacter pylori B38 8208497 YP_003058023.1 CDS HELPY_1365 NC_012973.1 1348662 1349324 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1348662..1349324 Helicobacter pylori B38 8208194 YP_003058024.1 CDS lon NC_012973.1 1349367 1351844 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15606774, 11325926, 7961402; Product type e : enzyme; ATP-dependent protease La 1349367..1351844 Helicobacter pylori B38 8208195 YP_003058025.1 CDS tyrA NC_012973.1 1351841 1352680 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1351841..1352680 Helicobacter pylori B38 8208735 YP_003058026.1 CDS HELPY_1368 NC_012973.1 1352716 1352949 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1352716..1352949 Helicobacter pylori B38 8209068 YP_003058027.1 CDS HELPY_1369 NC_012973.1 1353008 1353871 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; DNA/RNA endonuclease G (nucG) complement(1353008..1353871) Helicobacter pylori B38 8208196 YP_003058028.1 CDS HELPY_1370 NC_012973.1 1354142 1356022 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426350; Product type pe : enzyme; type III restriction enzyme M protein complement(1354142..1356022) Helicobacter pylori B38 8208197 YP_003058029.1 CDS HELPY_1371 NC_012973.1 1356016 1358562 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12426350; Product type pe : enzyme; type III restriction enzyme R protein complement(1356016..1358562) Helicobacter pylori B38 8208198 YP_003058030.1 CDS bioB NC_012973.1 1358767 1359615 D catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase 1358767..1359615 Helicobacter pylori B38 8208199 YP_003058031.1 CDS rbn NC_012973.1 1359615 1360493 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15764599, 10625642; Product type e : enzyme; ribonuclease N 1359615..1360493 Helicobacter pylori B38 8208405 YP_003058033.1 CDS HELPY_1380 NC_012973.1 1367410 1368315 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1367410..1368315 Helicobacter pylori B38 8208202 YP_003058034.1 CDS queF NC_012973.1 1368435 1368881 R NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(1368435..1368881) Helicobacter pylori B38 8208203 YP_003058035.1 CDS HELPY_1382 NC_012973.1 1368941 1369282 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1368941..1369282 Helicobacter pylori B38 8208900 YP_003058036.1 CDS miaA NC_012973.1 1369383 1370186 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1369383..1370186 Helicobacter pylori B38 8208204 YP_003058037.1 CDS HELPY_1384 NC_012973.1 1370187 1371290 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9334165; Product type pe : enzyme; lipopolysaccharide biosynthesis protein; LPS glycosyltransferase 1370187..1371290 Helicobacter pylori B38 8208757 YP_003058038.1 CDS murB NC_012973.1 1373058 1373837 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1373058..1373837) Helicobacter pylori B38 8208207 YP_003058039.1 CDS fliQ NC_012973.1 1373841 1374107 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(1373841..1374107) Helicobacter pylori B38 8208784 YP_003058040.1 CDS fliI NC_012973.1 1374118 1375422 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(1374118..1375422) Helicobacter pylori B38 8208543 YP_003058041.1 CDS HELPY_1390 NC_012973.1 1375423 1376337 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type IV secretion system ATPase complement(1375423..1376337) Helicobacter pylori B38 8208538 YP_003058042.1 CDS ileS NC_012973.1 1376354 1379116 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1376354..1379116) Helicobacter pylori B38 8208208 YP_003058043.1 CDS HELPY_1392 NC_012973.1 1379141 1379395 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; RNA binding protein complement(1379141..1379395) Helicobacter pylori B38 8208708 YP_003058044.1 CDS HELPY_1393 NC_012973.1 1379497 1380117 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1379497..1380117 Helicobacter pylori B38 8208209 YP_003058045.1 CDS HELPY_1396 NC_012973.1 1381384 1381605 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1381384..1381605) Helicobacter pylori B38 8208212 YP_003058046.1 CDS HELPY_1397 NC_012973.1 1381812 1382885 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(1381812..1382885) Helicobacter pylori B38 8208213 YP_003058047.1 CDS HELPY_1398 NC_012973.1 1382882 1383865 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16199563, 11956197; Product type pe : enzyme; phosphosugar isomerase complement(1382882..1383865) Helicobacter pylori B38 8208214 YP_003058048.1 CDS rnjA NC_012973.1 1383855 1385933 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15831787; Product type e : enzyme; ribonuclease J complement(1383855..1385933) Helicobacter pylori B38 8208215 YP_003058049.1 CDS ksgA NC_012973.1 1385971 1386786 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1385971..1386786) Helicobacter pylori B38 8208931 YP_003058050.1 CDS HELPY_1401 NC_012973.1 1387050 1387295 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1387050..1387295 Helicobacter pylori B38 8208726 YP_003058051.1 CDS HELPY_1402 NC_012973.1 1387748 1388836 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type I restriction enzyme specificity protein complement(1387748..1388836) Helicobacter pylori B38 8208216 YP_003058052.1 CDS purU NC_012973.1 1388878 1389759 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 94042872, 7868604; Product type e : enzyme; formyltetrahydrofolate deformylase complement(1388878..1389759) Helicobacter pylori B38 8208217 YP_003058053.1 CDS sppA NC_012973.1 1389762 1390640 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1598279, 15819627, 12791143, 86250892, 87222172; Product type e : enzyme; Signal peptide protease IV (Protease IV) (Endopeptidase IV) complement(1389762..1390640) Helicobacter pylori B38 8208888 YP_003058054.1 CDS HELPY_1405 NC_012973.1 1390711 1390968 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1390711..1390968 Helicobacter pylori B38 8209019 YP_003058055.1 CDS HELPY_1406 NC_012973.1 1391219 1391905 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1391219..1391905 Helicobacter pylori B38 8208218 YP_003058056.1 CDS HELPY_1407 NC_012973.1 1391916 1393085 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1391916..1393085 Helicobacter pylori B38 8208219 YP_003058057.1 CDS HELPY_1408 NC_012973.1 1393095 1393376 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1393095..1393376 Helicobacter pylori B38 8208220 YP_003058058.1 CDS HELPY_1411 NC_012973.1 1395910 1396689 R Evidence 4b : Only in Helicobacter genus; hypothetical protein complement(1395910..1396689) Helicobacter pylori B38 8208315 YP_003058059.1 CDS ppiB NC_012973.1 1396808 1397299 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15479239, 12089032, 9748346, 9268657, 8022278; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase 1396808..1397299 Helicobacter pylori B38 8208222 YP_003058060.1 CDS csrA NC_012973.1 1397318 1397548 D affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator 1397318..1397548 Helicobacter pylori B38 8208868 YP_003058061.1 CDS ispE NC_012973.1 1397545 1398351 D catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1397545..1398351 Helicobacter pylori B38 8208443 YP_003058062.1 CDS smpB NC_012973.1 1398348 1398806 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1398348..1398806 Helicobacter pylori B38 8208718 YP_003058063.1 CDS exbD3 NC_012973.1 1398812 1399264 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; Biopolymer transport protein ExbD/TolR; membrane protein 1398812..1399264 Helicobacter pylori B38 8209014 YP_003058064.1 CDS exbB3 NC_012973.1 1399275 1399676 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16741124, 12890020, 9811664, 9643536, 9159515, 7642501, 2670903; Product type t : transporter; Biopolymer transport accessory protein ExbD/TolR 1399275..1399676 Helicobacter pylori B38 8208492 YP_003058065.1 CDS rpmH NC_012973.1 1399748 1399882 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1399748..1399882 Helicobacter pylori B38 8208489 YP_003058066.1 CDS rnpA NC_012973.1 1399842 1400327 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12799461, 11376143, 9180701, 1689306, 1374553; Product type e : enzyme; ribonuclease P 1399842..1400327 Helicobacter pylori B38 8208967 YP_003058067.1 CDS HELPY_1419 NC_012973.1 1400314 1400667 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1400314..1400667 Helicobacter pylori B38 8208932 YP_003058068.1 CDS HELPY_1420 NC_012973.1 1400673 1402313 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1400673..1402313 Helicobacter pylori B38 8208223 YP_003058069.1 CDS HELPY_1421 NC_012973.1 1402313 1403110 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1402313..1403110 Helicobacter pylori B38 8208224 YP_003058070.1 CDS trmE NC_012973.1 1403103 1404455 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1403103..1404455 Helicobacter pylori B38 8208225 YP_003058071.1 CDS homD NC_012973.1 1404655 1406895 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9430586, 9252185; Product type m : membrane component; outer membrane protein HomD 1404655..1406895 Helicobacter pylori B38 8209029 YP_003058072.1 CDS HELPY_1424 NC_012973.1 1406913 1407107 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1406913..1407107) Helicobacter pylori B38 8208647 YP_003058073.1 CDS HELPY_1425 NC_012973.1 1407485 1408396 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1407485..1408396) Helicobacter pylori B38 8208226 YP_003058074.1 CDS HELPY_1426 NC_012973.1 1408406 1408747 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1408406..1408747) Helicobacter pylori B38 8208227 YP_003058075.1 CDS lpp20 NC_012973.1 1408755 1409282 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16484186, 1282312, 12738392, 11211867, 10816482, 7928954; Product type lp : lipoprotein; Membrane-associated lipoprotein complement(1408755..1409282) Helicobacter pylori B38 8208228 YP_003058076.1 CDS HELPY_1428 NC_012973.1 1409306 1409938 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1409306..1409938) Helicobacter pylori B38 8208737 YP_003058077.1 CDS trx2 NC_012973.1 1410298 1410612 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16354674, 12832786, 12399485, 11222594, 10671551; Product type f : factor; thioredoxin complement(1410298..1410612) Helicobacter pylori B38 8208229 YP_003058078.1 CDS rluB NC_012973.1 1410668 1411441 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16712869, 12762017, 12581659, 11720289, 10902565, 7612632; Product type e : enzyme; Ribosomal large subunit pseudouridine synthase B complement(1410668..1411441) Helicobacter pylori B38 8209061 YP_003058079.1 CDS dnaE NC_012973.1 1411438 1415073 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(1411438..1415073) Helicobacter pylori B38 8208924 YP_003058080.1 CDS HELPY_1432 NC_012973.1 1415232 1416284 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8591033; Product type pe : enzyme; di-heme cytochrome c peroxidase 1415232..1416284 Helicobacter pylori B38 8208464 YP_003058081.1 CDS HELPY_1434 NC_012973.1 1416581 1417168 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1416581..1417168) Helicobacter pylori B38 8208230 YP_003058082.1 CDS HELPY_1435 NC_012973.1 1417180 1417857 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1417180..1417857) Helicobacter pylori B38 8208231 YP_003058083.1 CDS HELPY_1436 NC_012973.1 1417860 1418675 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9658016, 8367727; Product type t : transporter; ABC transporter substrate-binding protein complement(1417860..1418675) Helicobacter pylori B38 8208232 YP_003058084.1 CDS HELPY_1437 NC_012973.1 1418660 1419448 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10518715; Product type t : transporter; ABC transporter ATP-binding protein complement(1418660..1419448) Helicobacter pylori B38 8208233 YP_003058085.1 CDS HELPY_1438 NC_012973.1 1419445 1420578 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9658016, 8367727; Product type t : transporter; ABC transporter permease complement(1419445..1420578) Helicobacter pylori B38 8208234 YP_003058086.1 CDS HELPY_1439 NC_012973.1 1420713 1421408 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; outer membrane protein 1420713..1421408 Helicobacter pylori B38 8208235 YP_003058087.1 CDS ilvE NC_012973.1 1421413 1422435 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1421413..1422435) Helicobacter pylori B38 8208236 YP_003058088.1 CDS horJ NC_012973.1 1422487 1423233 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 10454640; Product type m : membrane component; outer membrane protein HorJ complement(1422487..1423233) Helicobacter pylori B38 8208710 YP_003058089.1 CDS polA NC_012973.1 1423348 1426017 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16421093, 14712068, 12649320, 11283163, 8451181; Product type e : enzyme; DNA polymerase I (DNA nucleotidyltransferase (DNA-directed)) complement(1423348..1426017) Helicobacter pylori B38 8208672 YP_003058090.1 CDS HELPY_1446 NC_012973.1 1429413 1429988 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1429413..1429988) Helicobacter pylori B38 8208239 YP_003058091.1 CDS tmk NC_012973.1 1429976 1430551 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1429976..1430551) Helicobacter pylori B38 8208240 YP_003058092.1 CDS coaD NC_012973.1 1430553 1431026 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1430553..1431026) Helicobacter pylori B38 8209043 YP_003058093.1 CDS HELPY_1449 NC_012973.1 1431026 1431589 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1431026..1431589) Helicobacter pylori B38 8208725 YP_003058094.1 CDS flgA NC_012973.1 1431599 1432255 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1431599..1432255) Helicobacter pylori B38 8208241 YP_003058095.1 CDS uvrD NC_012973.1 1432252 1434297 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16135232, 15375374, 12527299, 11004168, 11879732; Product type e : enzyme; DNA helicase II (UvrD) complement(1432252..1434297) Helicobacter pylori B38 8208242 YP_003058096.1 CDS HELPY_1452 NC_012973.1 1434297 1436831 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1434297..1436831) Helicobacter pylori B38 8209086 YP_003058097.1 CDS serS NC_012973.1 1436841 1438088 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(1436841..1438088) Helicobacter pylori B38 8208243 YP_003058098.1 CDS HELPY_1454 NC_012973.1 1438089 1438886 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11380987, 7987228; Product type pe : enzyme; nitrilase/cyanide hydratase complement(1438089..1438886) Helicobacter pylori B38 8209012 YP_003058099.1 CDS HELPY_1455 NC_012973.1 1438890 1439150 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1438890..1439150) Helicobacter pylori B38 8208244 YP_003058100.1 CDS ubiE NC_012973.1 1439160 1439900 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(1439160..1439900) Helicobacter pylori B38 8208245 YP_003058101.1 CDS HELPY_1457 NC_012973.1 1439910 1440356 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1439910..1440356) Helicobacter pylori B38 8209072 YP_003058102.1 CDS HELPY_1458 NC_012973.1 1440367 1440939 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1440367..1440939) Helicobacter pylori B38 8208246 YP_003058103.1 CDS HELPY_1459 NC_012973.1 1440926 1442056 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease complement(1440926..1442056) Helicobacter pylori B38 8208247 YP_003058104.1 CDS HELPY_1460 NC_012973.1 1442053 1443150 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; ABC transporter permease complement(1442053..1443150) Helicobacter pylori B38 8208248 YP_003058105.1 CDS HELPY_1461 NC_012973.1 1443162 1444151 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pt : transporter; hypothetical protein complement(1443162..1444151) Helicobacter pylori B38 8208249 YP_003058106.1 CDS HELPY_1462 NC_012973.1 1444163 1445695 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane transporter complement(1444163..1445695) Helicobacter pylori B38 8208250 YP_003058107.1 CDS HELPY_1463 NC_012973.1 1445692 1447041 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16177343, 10531273; Product type pm : membrane component; TlyC-like hemolysin; membrane protein complement(1445692..1447041) Helicobacter pylori B38 8208251 YP_003058108.1 CDS HELPY_1464 NC_012973.1 1447144 1448745 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7732001; Product type t : transporter; transporter; phosphate transporter; membrane protein complement(1447144..1448745) Helicobacter pylori B38 8208252 YP_003058109.1 CDS HELPY_1465 NC_012973.1 1448886 1449155 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8875867, 8048161; Product type pf : factor; nifU-like protein 1448886..1449155 Helicobacter pylori B38 8208253 YP_003058110.1 CDS HELPY_1466 NC_012973.1 1449167 1449778 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1449167..1449778 Helicobacter pylori B38 8208254 YP_003058111.1 CDS murE NC_012973.1 1449782 1451125 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1449782..1451125 Helicobacter pylori B38 8208255 YP_003058112.1 CDS tal NC_012973.1 1451129 1452079 D Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1451129..1452079 Helicobacter pylori B38 8208787 YP_003058113.1 CDS rplY NC_012973.1 1452134 1452670 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1452134..1452670 Helicobacter pylori B38 8209024 YP_003058114.1 CDS pth NC_012973.1 1452680 1453240 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1452680..1453240 Helicobacter pylori B38 8208961 YP_003058115.1 CDS HELPY_1471 NC_012973.1 1453250 1454317 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; permease; membrane protein 1453250..1454317 Helicobacter pylori B38 8208884 YP_003058116.1 CDS HELPY_1472 NC_012973.1 1454438 1455358 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1454438..1455358 Helicobacter pylori B38 8208256 YP_003058117.1 CDS HELPY_1473 NC_012973.1 1455435 1455608 D Evidence 6 : Doubtful CDS; hypothetical protein 1455435..1455608 Helicobacter pylori B38 8208257 YP_003058118.1 CDS hopK NC_012973.1 1455671 1456837 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16322107, 16173498, 15918181, 12454856, 11925614, 9252185; Product type m : membrane component; outer membrane protein HorK complement(1455671..1456837) Helicobacter pylori B38 8208258 YP_003058119.1 CDS HELPY_1475 NC_012973.1 1457016 1457453 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1457016..1457453 Helicobacter pylori B38 8208659 YP_003058120.1 CDS copA NC_012973.1 1457450 1459801 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16804172, 9440521, 9244252, 9398888, 16269744, 12974640, 9188683; Product type t : transporter; ATPase, P-type copper-transporter; membrane protein complement(1457450..1459801) Helicobacter pylori B38 8208259 YP_003058121.1 CDS HELPY_1477 NC_012973.1 1459827 1460543 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1459827..1460543) Helicobacter pylori B38 8208438 YP_003058122.1 CDS ribD NC_012973.1 1460525 1461559 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11024263, 9068650; Product type e : enzyme; Riboflavin biosynthesis protein RibD complement(1460525..1461559) Helicobacter pylori B38 8208260 YP_003058123.1 CDS gltS NC_012973.1 1461556 1462782 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12664155, 2254324, 8596452, 2017136; Product type t : transporter; transporter, GltS family; membrane protein complement(1461556..1462782) Helicobacter pylori B38 8208920 YP_003058124.1 CDS HELPY_1480 NC_012973.1 1462868 1464067 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17513436; Product type pe : enzyme; saccharopine dehydrogenase 1462868..1464067 Helicobacter pylori B38 8208590 YP_003058125.1 CDS HELPY_1481 NC_012973.1 1464077 1465453 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16645308, 16143852, 15134648, 12709048, 11734195, 9785959; Product type c : carrier; ferredoxin-like protein complement(1464077..1465453) Helicobacter pylori B38 8208261 YP_003058126.1 CDS HELPY_1482 NC_012973.1 1465559 1466221 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1465559..1466221 Helicobacter pylori B38 8208262 YP_003058127.1 CDS folB NC_012973.1 1466218 1466571 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9651328; Product type e : enzyme; Dihydroneopterin aldolase 1466218..1466571 Helicobacter pylori B38 8208263 YP_003058128.1 CDS HELPY_1484 NC_012973.1 1466588 1466881 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1466588..1466881 Helicobacter pylori B38 8208548 YP_003058129.1 CDS frpB3 NC_012973.1 1467035 1469674 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12704139, 12165031, 16914236; Product type m : membrane component; Iron-regulated outer membrane protein 1467035..1469674 Helicobacter pylori B38 8208264 YP_003058130.1 CDS selA NC_012973.1 1469901 1471061 D catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1469901..1471061 Helicobacter pylori B38 8208559 YP_003058131.1 CDS nusA NC_012973.1 1471158 1472345 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1471158..1472345 Helicobacter pylori B38 8209009 YP_003058132.1 CDS HELPY_1490 NC_012973.1 1473330 1473686 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1473330..1473686) Helicobacter pylori B38 8208266 YP_003058133.1 CDS HELPY_1491 NC_012973.1 1474270 1478010 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type pe : enzyme; type IIS restriction-modification protein complement(1474270..1478010) Helicobacter pylori B38 8208267 YP_003058134.1 CDS res NC_012973.1 1478213 1481119 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12426350, 2837577; Product type e : enzyme; type III R-M system restriction enzyme complement(1478213..1481119) Helicobacter pylori B38 8208268 YP_003058135.1 CDS recG NC_012973.1 1483100 1484971 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1483100..1484971) Helicobacter pylori B38 8208768 YP_003058136.1 CDS HELPY_1496 NC_012973.1 1485050 1485400 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1485050..1485400 Helicobacter pylori B38 8208906 YP_003058137.1 CDS HELPY_1497 NC_012973.1 1485404 1486039 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein 1485404..1486039 Helicobacter pylori B38 8208269 YP_003058138.1 CDS HELPY_1498 NC_012973.1 1486036 1486788 R AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III complement(1486036..1486788) Helicobacter pylori B38 8208270 YP_003058139.1 CDS comH NC_012973.1 1486968 1488407 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16436074, 16428391, 15516585, 12933898, 12868652, 1148912, 1086902; Product type f : factor; DNA transformation competence protein ComH complement(1486968..1488407) Helicobacter pylori B38 8208325 YP_003058140.1 CDS dnaA NC_012973.1 1488636 1490003 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(1488636..1490003) Helicobacter pylori B38 8208436 YP_003058141.1 CDS HELPY_1501 NC_012973.1 1490156 1490698 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9058966; Product type e : enzyme; purine nucleoside phosphorylase PunB 1490156..1490698 Helicobacter pylori B38 8208462 YP_003058142.1 CDS HELPY_1502 NC_012973.1 1490741 1490980 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1490741..1490980 Helicobacter pylori B38 8208272 YP_003058143.1 CDS glmS NC_012973.1 1490981 1492774 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1490981..1492774 Helicobacter pylori B38 8208273 YP_003058144.1 CDS thyX NC_012973.1 1492796 1493422 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1492796..1493422 Helicobacter pylori B38 8208586 YP_003058145.1 CDS HELPY_1505 NC_012973.1 1493576 1493668 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1493576..1493668 Helicobacter pylori B38 8209036 YP_003058146.1 CDS HELPY_1506 NC_012973.1 1493750 1494871 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type pe : enzyme; type I R-M system specificity subunit complement(1493750..1494871) Helicobacter pylori B38 8208274 YP_003058147.1 CDS hsdM3 NC_012973.1 1494880 1497330 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type e : enzyme; type I restriction-modification enzyme subunit M complement(1494880..1497330) Helicobacter pylori B38 8208275 YP_003058148.1 CDS hsdR3 NC_012973.1 1497398 1500364 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type e : enzyme; type I restriction-modification enzyme subunit R 1497398..1500364 Helicobacter pylori B38 8208687 YP_003058149.1 CDS HELPY_1509 NC_012973.1 1500364 1501071 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1500364..1501071 Helicobacter pylori B38 8208688 YP_003058150.1 CDS fecA3 NC_012973.1 1501170 1503698 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10713425, 12165031, 16718597, 16333751, 16193283, 12948487, 12732308; Product type t : transporter; Iron(III) dicitrate transport protein FecA complement(1501170..1503698) Helicobacter pylori B38 8208276 YP_003058151.1 CDS rocF NC_012973.1 1504232 1505200 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 16672598, 15128304, 11717441, 10931887, 10572136, 7540694; Product type e : enzyme; Arginase complement(1504232..1505200) Helicobacter pylori B38 8208502 YP_003058152.1 CDS ald NC_012973.1 1505404 1506546 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16816198, 12193615, 9168598; Product type e : enzyme; Alanine dehydrogenase 1505404..1506546 Helicobacter pylori B38 8208934 YP_003058153.1 CDS HELPY_1514 NC_012973.1 1506670 1508421 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1506670..1508421 Helicobacter pylori B38 8208372 YP_003058154.1 CDS horL NC_012973.1 1508432 1509160 R Evidence 1a : Function experimentally demonstrated in the studied strain; Product type m : membrane component; outer membrane protein HorL complement(1508432..1509160) Helicobacter pylori B38 8208277 YP_003058155.1 CDS ppnK NC_012973.1 1509346 1510200 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511117, 11488932, 11006082; Product type e : enzyme; inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase) 1509346..1510200 Helicobacter pylori B38 8208673 YP_003058156.1 CDS recN NC_012973.1 1510221 1511795 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16780573, 16079351, 15948952, 15186413, 12670973, 11807051; Product type cp : cell process; DNA repair protein 1510221..1511795 Helicobacter pylori B38 8208871 YP_003058157.1 CDS HELPY_1518 NC_012973.1 1511792 1513099 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fibronectin/fibrinogen-binding protein 1511792..1513099 Helicobacter pylori B38 8208908 YP_003058158.1 CDS HELPY_1519 NC_012973.1 1513118 1513414 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1513118..1513414 Helicobacter pylori B38 8208278 YP_003058159.1 CDS HELPY_1520 NC_012973.1 1513749 1514027 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1513749..1514027 Helicobacter pylori B38 8208279 YP_003058160.1 CDS HELPY_1521 NC_012973.1 1514027 1515151 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II integrase 1514027..1515151 Helicobacter pylori B38 8208280 YP_003058161.1 CDS HELPY_1522 NC_012973.1 1515148 1515288 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1515148..1515288 Helicobacter pylori B38 8208281 YP_003058162.1 CDS HELPY_1523 NC_012973.1 1515363 1515683 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1515363..1515683 Helicobacter pylori B38 8208282 YP_003058163.1 CDS HELPY_1524 NC_012973.1 1515670 1515810 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1515670..1515810 Helicobacter pylori B38 8208283 YP_003058164.1 CDS HELPY_1525 NC_012973.1 1515811 1516740 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1515811..1516740 Helicobacter pylori B38 8208284 YP_003058165.1 CDS HELPY_1527 NC_012973.1 1516951 1517241 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16789826; Product type h : extrachromosomal origin; Hac prophage II protein 1516951..1517241 Helicobacter pylori B38 8208285 YP_003058166.1 CDS HELPY_1529 NC_012973.1 1517857 1519086 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; transposase, OrfB, ISHp609 complement(1517857..1519086) Helicobacter pylori B38 8208287 YP_003058167.1 CDS HELPY_1530 NC_012973.1 1519073 1519705 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16788065, 15516563, 10986230, 10537187, 9987116; Product type e : enzyme; Serine recombinase-transposase, OrfA, ISHp609 complement(1519073..1519705) Helicobacter pylori B38 8208288 YP_003058168.1 CDS HELPY_1531 NC_012973.1 1519702 1519887 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1519702..1519887) Helicobacter pylori B38 8208289 YP_003058169.1 CDS HELPY_1532 NC_012973.1 1519889 1520146 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1519889..1520146) Helicobacter pylori B38 8208290 YP_003058170.1 CDS hcpG NC_012973.1 1521000 1521977 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11777911, 10748053, 99369890, 16040986; Product type f : factor; hypothetical protein 1521000..1521977 Helicobacter pylori B38 8208292 YP_003058171.1 CDS dnaQ NC_012973.1 1522016 1522879 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1522016..1522879) Helicobacter pylori B38 8208618 YP_003058172.1 CDS rpe NC_012973.1 1522857 1523510 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(1522857..1523510) Helicobacter pylori B38 8208470 YP_003058173.1 CDS fbp NC_012973.1 1523581 1524453 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1523581..1524453 Helicobacter pylori B38 8208936 YP_003058174.1 CDS HELPY_1538 NC_012973.1 1524453 1524656 D Evidence 4c : Only in epsilon proteobacteria; hypothetical protein 1524453..1524656 Helicobacter pylori B38 8208499 YP_003058175.1 CDS HELPY_1539 NC_012973.1 1524669 1525565 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16217547, 14711809, 12490707, 12426350, 12034832, 11956101, 11703661; Product type pe : enzyme; N-6 Adenine-specific DNA methylase 1524669..1525565 Helicobacter pylori B38 8208293 YP_003058176.1 CDS HELPY_1540 NC_012973.1 1525868 1526290 D Evidence 4a : Only in Helicobacter pylori; hypothetical protein 1525868..1526290 Helicobacter pylori B38 8208294 YP_003058177.1 CDS petC NC_012973.1 1526407 1527264 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15262969, 12672829; Product type e : enzyme; Ubiquinol cytochrome c oxidoreductase, cytochrome c subunit complement(1526407..1527264) Helicobacter pylori B38 8208295 YP_003058178.1 CDS petB NC_012973.1 1527261 1528499 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15262969, 12672829; Product type e : enzyme; Ubiquinol cytochrome c oxidoreductase, cytochrome b subunit; membrane protein complement(1527261..1528499) Helicobacter pylori B38 8208850 YP_003058179.1 CDS petA NC_012973.1 1528510 1529013 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15262969, 12672829; Product type e : enzyme; Ubiquinol cytochrome c oxidoreductase, 2Fe-2S subunit complement(1528510..1529013) Helicobacter pylori B38 8208849 YP_003058180.1 CDS mfd NC_012973.1 1529148 1532135 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16551743, 16511235, 16469698, 16309703, 15720542; Product type f : factor; transcription-repair coupling factor complement(1529148..1532135) Helicobacter pylori B38 8208848 YP_003058181.1 CDS HELPY_1545 NC_012973.1 1532139 1532549 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1532139..1532549) Helicobacter pylori B38 8208756 YP_003058182.1 CDS tagE1 NC_012973.1 1532468 1533406 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7523253, 9457886; Product type e : enzyme; Zn-metallopeptidase, M23 family complement(1532468..1533406) Helicobacter pylori B38 8208296 YP_003058183.1 CDS tagE2 NC_012973.1 1533415 1534344 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7523253, 9457886; Product type e : enzyme; Zn-metallopeptidase, M23 family complement(1533415..1534344) Helicobacter pylori B38 8209022 YP_003058184.1 CDS folC NC_012973.1 1534341 1535516 R [Folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase); Dihydrofolate synthase]; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8304196, 9618466; Product type e : enzyme; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(1534341..1535516) Helicobacter pylori B38 8209023 YP_003058185.1 CDS HELPY_1549 NC_012973.1 1535506 1536018 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1535506..1536018) Helicobacter pylori B38 8208549 YP_003058186.1 CDS leuS NC_012973.1 1536015 1538441 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(1536015..1538441) Helicobacter pylori B38 8208297 YP_003058187.1 CDS HELPY_1551 NC_012973.1 1538448 1538786 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1538448..1538786) Helicobacter pylori B38 8208729 YP_003058188.1 CDS secF NC_012973.1 1538796 1539767 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(1538796..1539767) Helicobacter pylori B38 8208298 YP_003058189.1 CDS secD NC_012973.1 1539776 1541353 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(1539776..1541353) Helicobacter pylori B38 8209006 YP_003058190.1 CDS yajC NC_012973.1 1541350 1541733 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(1541350..1541733) Helicobacter pylori B38 8209004 YP_003058191.1 CDS nhaA NC_012973.1 1541781 1543130 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(1541781..1543130) Helicobacter pylori B38 8209094 YP_003058192.1 CDS pcrA NC_012973.1 1543121 1545958 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 91267926, 9288744; Product type e : enzyme; recombination protein RecB complement(1543121..1545958) Helicobacter pylori B38 8208799 YP_003058193.1 CDS rpsB NC_012973.1 1546206 1547000 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1546206..1547000 Helicobacter pylori B38 8208843 YP_003058194.1 CDS tsf NC_012973.1 1547000 1548067 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1547000..1548067 Helicobacter pylori B38 8208976 YP_003058195.1 CDS pbp3 NC_012973.1 1548514 1550361 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 83296957, 96404787, 98268991, 99058131, 98190796, 91207040; Product type e : enzyme; Penicillin-binding protein 3 complement(1548514..1550361) Helicobacter pylori B38 8209065 YP_003058196.1 CDS fliE NC_012973.1 1550517 1550846 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1550517..1550846) Helicobacter pylori B38 8208840 YP_003058197.1 CDS flgC NC_012973.1 1550974 1551459 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(1550974..1551459) Helicobacter pylori B38 8208534 YP_003058198.1 CDS flgB NC_012973.1 1551472 1551894 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB complement(1551472..1551894) Helicobacter pylori B38 8208517 YP_003058199.1 CDS ftsW NC_012973.1 1552099 1553265 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16040206, 15773984, 15752189, 15576787; Product type cp : cell process; cell division protein FtsW 1552099..1553265 Helicobacter pylori B38 8208516 YP_003058200.1 CDS HELPY_1564 NC_012973.1 1553288 1554295 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter substrate-binding protein complement(1553288..1554295) Helicobacter pylori B38 8208566 YP_003058201.1 CDS tsaA NC_012973.1 1554535 1555131 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11843959, 15102813, 8041738; Product type e : enzyme; Alkyl hydroperoxide reductase 1554535..1555131 Helicobacter pylori B38 8208299 YP_003058202.1 CDS metQ NC_012973.1 1555277 1556092 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12169620; Product type lp : lipoprotein; D-methionine-binding lipoprotein metQ (outer membrane lipoprotein 1) 1555277..1556092 Helicobacter pylori B38 8209064 YP_003058203.1 CDS pbp2 NC_012973.1 1556572 1558338 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11181392; Product type e : enzyme; Penicillin-binding protein PBP2 complement(1556572..1558338) Helicobacter pylori B38 8208754 YP_003058204.1 CDS HELPY_1569 NC_012973.1 1558319 1558762 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1558319..1558762) Helicobacter pylori B38 8208839 YP_003058205.1 CDS engB NC_012973.1 1558775 1559401 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1558775..1559401) Helicobacter pylori B38 8208300 YP_003058206.1 CDS HELPY_1571 NC_012973.1 1559398 1559949 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1559398..1559949) Helicobacter pylori B38 8208484 YP_003058207.1 CDS HELPY_1572 NC_012973.1 1559949 1560542 R Evidence 4c : Only in epsilon proteobacteria; hypothetical protein complement(1559949..1560542) Helicobacter pylori B38 8208301 YP_003058208.1 CDS kdsC NC_012973.1 1560517 1561011 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12639950; Product type e : enzyme; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase complement(1560517..1561011) Helicobacter pylori B38 8208302 YP_003058209.1 CDS HELPY_1574 NC_012973.1 1561008 1561952 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3316191; Product type lp : lipoprotein; lipoprotein complement(1561008..1561952) Helicobacter pylori B38 8208724 YP_003058210.1 CDS mltD NC_012973.1 1561952 1563070 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 15694856, 10469189, 10368145; Product type e : enzyme; Lytic murein transglycosylase D (Murein hydrolase D) complement(1561952..1563070) Helicobacter pylori B38 8208303 YP_003058211.1 CDS HELPY_1576 NC_012973.1 1563159 1563923 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10747959; Product type e : enzyme; Deoxyribonuclease complement(1563159..1563923) Helicobacter pylori B38 8208761 YP_003058212.1 CDS ribC NC_012973.1 1563998 1564618 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1563998..1564618 Helicobacter pylori B38 8208304 YP_003058213.1 CDS HELPY_1578 NC_012973.1 1564619 1564891 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1564619..1564891 Helicobacter pylori B38 8208919 YP_003058214.1 CDS metN NC_012973.1 1564910 1565893 D part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 1564910..1565893 Helicobacter pylori B38 8208305 YP_003058215.1 CDS HELPY_1580 NC_012973.1 1565895 1566542 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12218041, 9294450; Product type t : transporter; ABC transporter permease; D-and L-methionine transport protein; membrane protein 1565895..1566542 Helicobacter pylori B38 8208360 YP_003058216.1 CDS HELPY_1582 NC_012973.1 1566574 1567692 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; LPS biosynthesis protein, glycosyltransferase complement(1566574..1567692) Helicobacter pylori B38 8208306 YP_003058217.1 CDS HELPY_1583 NC_012973.1 1567741 1568169 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1567741..1568169) Helicobacter pylori B38 8208307 YP_003058218.1 CDS HELPY_1584 NC_012973.1 1568179 1568775 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein complement(1568179..1568775) Helicobacter pylori B38 8208308 YP_003058219.1 CDS wecA NC_012973.1 1568772 1569782 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15908345, 1575219, 11832520, 11700352, 10629198; Product type e : enzyme; UDP-phosphate N-acetylgalactosaminyl-1-phosphate transferase complement(1568772..1569782) Helicobacter pylori B38 8208309 YP_003058220.1 CDS pdxJ NC_012973.1 1569918 1570706 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1569918..1570706 Helicobacter pylori B38 8209092 YP_003058221.1 CDS pdxA NC_012973.1 1570708 1571631 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1570708..1571631 Helicobacter pylori B38 8208844 YP_003058222.1 CDS HELPY_1588 NC_012973.1 1571696 1572718 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1571696..1572718 Helicobacter pylori B38 8208310 YP_003058223.1 CDS flgG NC_012973.1 1572895 1573683 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1572895..1573683 Helicobacter pylori B38 8208311 YP_003058224.1 CDS HELPY_1590 NC_012973.1 1573680 1574288 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1573680..1574288) Helicobacter pylori B38 8208522 YP_003058225.1 CDS HELPY_1591 NC_012973.1 1574716 1574856 R Evidence 4a : Only in Helicobacter pylori; hypothetical protein complement(1574716..1574856) Helicobacter pylori B38 8208312 YP_003058226.1 CDS HELPY_1592 NC_012973.1 1574941 1575702 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1574941..1575702) Helicobacter pylori B38 8208313 YP_003058227.1 CDS HELPY_1593 NC_012973.1 1575962 1576681 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1575962..1576681) Helicobacter pylori B38 8208314 HELPY_tRNA36 tRNA HELPY_tRNA36 NC_012973.1 4133 4208 R tRNA-Glu complement(4133..4208) Helicobacter pylori B38 8208837 HELPY_tRNA35 tRNA HELPY_tRNA35 NC_012973.1 4272 4348 R tRNA-Asp complement(4272..4348) Helicobacter pylori B38 8208353 HELPY_tRNA34 tRNA HELPY_tRNA34 NC_012973.1 4389 4464 R tRNA-Val complement(4389..4464) Helicobacter pylori B38 8208352 HELPY_tRNA33 tRNA HELPY_tRNA33 NC_012973.1 4505 4579 R tRNA-Glu complement(4505..4579) Helicobacter pylori B38 8208351 HELPY_tRNA32 tRNA HELPY_tRNA32 NC_012973.1 4590 4665 R tRNA-Lys complement(4590..4665) Helicobacter pylori B38 8208350 HELPY_tRNA31 tRNA HELPY_tRNA31 NC_012973.1 72529 72604 R tRNA-Val complement(72529..72604) Helicobacter pylori B38 8209075 HELPY_tRNA1 tRNA HELPY_tRNA1 NC_012973.1 90816 90907 D tRNA-Ser 90816..90907 Helicobacter pylori B38 8208493 HELPY_tRNA30 tRNA HELPY_tRNA30 NC_012973.1 229108 229182 R tRNA-Asn complement(229108..229182) Helicobacter pylori B38 8207628 HELPY_tRNA29 tRNA HELPY_tRNA29 NC_012973.1 252057 252132 R tRNA-Ala complement(252057..252132) Helicobacter pylori B38 8207641 HELPY_tRNA2 tRNA HELPY_tRNA2 NC_012973.1 331831 331907 D tRNA-Arg 331831..331907 Helicobacter pylori B38 8208795 HELPY_tRNA28 tRNA HELPY_tRNA28 NC_012973.1 382356 382443 R tRNA-Ser complement(382356..382443) Helicobacter pylori B38 8208668 HELPY_tRNA27 tRNA HELPY_tRNA27 NC_012973.1 435644 435721 R tRNA-Pro complement(435644..435721) Helicobacter pylori B38 8208870 HELPY_tRNA26 tRNA HELPY_tRNA26 NC_012973.1 512432 512508 R tRNA-Arg complement(512432..512508) Helicobacter pylori B38 8207772 HELPY_tRNA3 tRNA HELPY_tRNA3 NC_012973.1 605120 605196 D tRNA-Met 605120..605196 Helicobacter pylori B38 8208935 HELPY_tRNA25 tRNA HELPY_tRNA25 NC_012973.1 872190 872266 R tRNA-Met complement(872190..872266) Helicobacter pylori B38 8208402 HELPY_tRNA24 tRNA HELPY_tRNA24 NC_012973.1 872279 872353 R tRNA-Gln complement(872279..872353) Helicobacter pylori B38 8208341 HELPY_tRNA4 tRNA HELPY_tRNA4 NC_012973.1 928451 928525 D tRNA-Gly 928451..928525 Helicobacter pylori B38 8207995 HELPY_tRNA5 tRNA HELPY_tRNA5 NC_012973.1 928567 928653 D tRNA-Leu 928567..928653 Helicobacter pylori B38 8208354 HELPY_tRNA6 tRNA HELPY_tRNA6 NC_012973.1 928727 928801 D tRNA-Cys 928727..928801 Helicobacter pylori B38 8208355 HELPY_tRNA7 tRNA HELPY_tRNA7 NC_012973.1 928849 928936 D tRNA-Ser 928849..928936 Helicobacter pylori B38 8208356 HELPY_tRNA23 tRNA HELPY_tRNA23 NC_012973.1 1005834 1005910 R tRNA-Arg complement(1005834..1005910) Helicobacter pylori B38 8208051 HELPY_tRNA22 tRNA HELPY_tRNA22 NC_012973.1 1005928 1006004 R tRNA-Arg complement(1005928..1006004) Helicobacter pylori B38 8208339 HELPY_tRNA21 tRNA HELPY_tRNA21 NC_012973.1 1006064 1006140 R tRNA-His complement(1006064..1006140) Helicobacter pylori B38 8208338 HELPY_tRNA20 tRNA HELPY_tRNA20 NC_012973.1 1006208 1006285 R tRNA-Pro complement(1006208..1006285) Helicobacter pylori B38 8208337 HELPY_tRNA19 tRNA HELPY_tRNA19 NC_012973.1 1056314 1056398 R tRNA-Leu complement(1056314..1056398) Helicobacter pylori B38 8208881 HELPY_tRNA8 tRNA HELPY_tRNA8 NC_012973.1 1061182 1061258 D tRNA-Ile 1061182..1061258 Helicobacter pylori B38 8208574 HELPY_tRNA9 tRNA HELPY_tRNA9 NC_012973.1 1061275 1061350 D tRNA-Ala 1061275..1061350 Helicobacter pylori B38 8208358 HELPY_tRNA18 tRNA HELPY_tRNA18 NC_012973.1 1155369 1155446 R tRNA-Met complement(1155369..1155446) Helicobacter pylori B38 8208108 HELPY_tRNA17 tRNA HELPY_tRNA17 NC_012973.1 1185174 1185249 R tRNA-Trp complement(1185174..1185249) Helicobacter pylori B38 8209005 HELPY_tRNA16 tRNA HELPY_tRNA16 NC_012973.1 1186809 1186883 R tRNA-Thr complement(1186809..1186883) Helicobacter pylori B38 8209066 HELPY_tRNA15 tRNA HELPY_tRNA15 NC_012973.1 1186914 1186990 R tRNA-Gly complement(1186914..1186990) Helicobacter pylori B38 8208331 HELPY_tRNA14 tRNA HELPY_tRNA14 NC_012973.1 1187007 1187091 R tRNA-Tyr complement(1187007..1187091) Helicobacter pylori B38 8208330 HELPY_tRNA13 tRNA HELPY_tRNA13 NC_012973.1 1187119 1187194 R tRNA-Thr complement(1187119..1187194) Helicobacter pylori B38 8208329 HELPY_tRNA12 tRNA HELPY_tRNA12 NC_012973.1 1192563 1192649 R tRNA-Leu complement(1192563..1192649) Helicobacter pylori B38 8208445 HELPY_tRNA11 tRNA HELPY_tRNA11 NC_012973.1 1192703 1192789 R tRNA-Leu complement(1192703..1192789) Helicobacter pylori B38 8208327 HELPY_tRNA10 tRNA HELPY_tRNA10 NC_012973.1 1486890 1486965 D tRNA-Phe 1486890..1486965 Helicobacter pylori B38 8208271 HELPY_5S_3 rRNA HELPY_5S_3 NC_012973.1 967897 968013 D ribosomal RNA 5S 967897..968013 Helicobacter pylori B38 8208020 HELPY_5S_2 rRNA HELPY_5S_2 NC_012973.1 984401 984534 R ribosomal RNA 5S complement(984401..984534) Helicobacter pylori B38 8208040 HELPY_23S_2 rRNA HELPY_23S_2 NC_012973.1 984762 987647 R ribosomal RNA 23S complement(984762..987647) Helicobacter pylori B38 8208320 HELPY_16S_2 rRNA HELPY_16S_2 NC_012973.1 1113127 1114628 R ribosomal RNA 16S complement(1113127..1114628) Helicobacter pylori B38 8208092 HELPY_5S_1 rRNA HELPY_5S_1 NC_012973.1 1360673 1360806 R ribosomal RNA 5S complement(1360673..1360806) Helicobacter pylori B38 8208903 HELPY_23S_1 rRNA HELPY_23S_1 NC_012973.1 1361034 1363919 R ribosomal RNA 23S complement(1361034..1363919) Helicobacter pylori B38 8208319 HELPY_16S_1 rRNA HELPY_16S_1 NC_012973.1 1393904 1395405 R ribosomal RNA 16S complement(1393904..1395405) Helicobacter pylori B38 8208221