-- dump date 20120504_151427 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 363253000001 SEQ_END SEQ_END NC_008011.1 1457619 1457619 DR NC_008011.1; contig end 1457619..1457619 Lawsonia intracellularis PHE/MN1-00 363253000002 SEQ_END SEQ_END NC_008012.1 27048 27048 DR NC_008012.1; contig end 27048..27048 Lawsonia intracellularis PHE/MN1-00 363253000003 SEQ_END SEQ_END NC_008013.1 39794 39794 DR NC_008013.1; contig end 39794..39794 Lawsonia intracellularis PHE/MN1-00 363253000004 SEQ_END SEQ_END NC_008014.1 194553 194553 DR NC_008014.1; contig end 194553..194553 Lawsonia intracellularis PHE/MN1-00 YP_594379.1 CDS dnaA NC_008011.1 358 1794 D DNA replication initiation ATPase 358..1794 Lawsonia intracellularis PHE/MN1-00 4060374 YP_594380.1 CDS prfA NC_008011.1 1827 2906 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1827..2906) Lawsonia intracellularis PHE/MN1-00 4060307 YP_594381.1 CDS LI0003 NC_008011.1 3122 3436 D hypothetical protein 3122..3436 Lawsonia intracellularis PHE/MN1-00 4060308 YP_594382.1 CDS hly NC_008011.1 3454 4209 D hemolysin A 3454..4209 Lawsonia intracellularis PHE/MN1-00 4059687 YP_594383.1 CDS sodC NC_008011.1 4337 4879 R superoxide dismutase precursor (Cu-Zn) complement(4337..4879) Lawsonia intracellularis PHE/MN1-00 4059803 YP_594384.1 CDS LI0006 NC_008011.1 4945 5214 D hypothetical protein 4945..5214 Lawsonia intracellularis PHE/MN1-00 4060309 YP_594385.1 CDS tlc NC_008011.1 5549 7147 D nucleotide transport protein 5549..7147 Lawsonia intracellularis PHE/MN1-00 4059826 YP_594386.1 CDS LI0008 NC_008011.1 7665 7904 R hypothetical protein complement(7665..7904) Lawsonia intracellularis PHE/MN1-00 4059474 YP_594387.1 CDS LI0009 NC_008011.1 8001 8735 R hypothetical protein complement(8001..8735) Lawsonia intracellularis PHE/MN1-00 4059475 YP_594388.1 CDS LI0010 NC_008011.1 8623 8928 R hypothetical protein complement(8623..8928) Lawsonia intracellularis PHE/MN1-00 4059476 YP_594389.1 CDS polB NC_008011.1 9617 10576 R DNA polymerase I complement(9617..10576) Lawsonia intracellularis PHE/MN1-00 4060002 YP_594390.1 CDS LI0012 NC_008011.1 10536 13571 R hypothetical protein complement(10536..13571) Lawsonia intracellularis PHE/MN1-00 4059477 YP_594391.1 CDS LI0013 NC_008011.1 14779 15576 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(14779..15576) Lawsonia intracellularis PHE/MN1-00 4059478 YP_594392.1 CDS LI0014 NC_008011.1 15573 16805 R recombination factor protein RarA complement(15573..16805) Lawsonia intracellularis PHE/MN1-00 4059479 YP_594393.1 CDS upp NC_008011.1 16842 17369 R pyrimidine operon attenuation protein/uracil phosphoribosyltransferase complement(16842..17369) Lawsonia intracellularis PHE/MN1-00 4059606 YP_594394.1 CDS LI0016 NC_008011.1 17612 18394 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 17612..18394 Lawsonia intracellularis PHE/MN1-00 4059480 YP_594395.1 CDS ubiE NC_008011.1 18406 19131 R ubiquinone/menaquinone biosynthesis methylase complement(18406..19131) Lawsonia intracellularis PHE/MN1-00 4059510 YP_594396.1 CDS gltP NC_008011.1 19389 20660 R proton/sodium-glutamate symport protein complement(19389..20660) Lawsonia intracellularis PHE/MN1-00 4060223 YP_594397.1 CDS tagD NC_008011.1 20974 21483 R glycerol-3-phosphate cytidyltransferase complement(20974..21483) Lawsonia intracellularis PHE/MN1-00 4059809 YP_594398.1 CDS trpS NC_008011.1 21519 22526 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(21519..22526) Lawsonia intracellularis PHE/MN1-00 4059499 YP_594399.1 CDS LI0021 NC_008011.1 22529 23203 R Zn-dependent proteases complement(22529..23203) Lawsonia intracellularis PHE/MN1-00 4059481 YP_594400.1 CDS tyrS NC_008011.1 23206 24402 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(23206..24402) Lawsonia intracellularis PHE/MN1-00 4059509 YP_594401.1 CDS ogt NC_008011.1 24563 25084 R O-6-alkylguanine-DNA/cysteine-protein methyltransferase complement(24563..25084) Lawsonia intracellularis PHE/MN1-00 4060071 YP_594402.1 CDS ispG NC_008011.1 25145 26224 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(25145..26224) Lawsonia intracellularis PHE/MN1-00 4060321 YP_594403.1 CDS ppsA NC_008011.1 26307 29891 R phosphoenolpyruvate synthase/pyruvate phosphate dikinase complement(26307..29891) Lawsonia intracellularis PHE/MN1-00 4059975 YP_594404.1 CDS birA NC_008011.1 30148 31131 R biotin-(acetyl-CoA carboxylase) ligase complement(30148..31131) Lawsonia intracellularis PHE/MN1-00 4060401 YP_594405.1 CDS fliM NC_008011.1 31207 32184 R flagellar motor switch protein complement(31207..32184) Lawsonia intracellularis PHE/MN1-00 4059743 YP_594406.1 CDS LI0028 NC_008011.1 32258 32746 D hypothetical protein 32258..32746 Lawsonia intracellularis PHE/MN1-00 4059482 YP_594407.1 CDS LI0029 NC_008011.1 32974 34476 R hypothetical protein complement(32974..34476) Lawsonia intracellularis PHE/MN1-00 4059483 YP_594408.1 CDS LI0030 NC_008011.1 34646 35818 R hypothetical protein complement(34646..35818) Lawsonia intracellularis PHE/MN1-00 4059484 YP_594409.1 CDS LI0031 NC_008011.1 35907 36365 R hypothetical protein complement(35907..36365) Lawsonia intracellularis PHE/MN1-00 4059485 YP_594410.1 CDS LI0032 NC_008011.1 36644 37960 R hypothetical protein complement(36644..37960) Lawsonia intracellularis PHE/MN1-00 4059486 YP_594411.1 CDS ostA NC_008011.1 38434 40854 R organic solvent tolerance protein OstA complement(38434..40854) Lawsonia intracellularis PHE/MN1-00 4060018 YP_594412.1 CDS alr NC_008011.1 40989 42131 D alanine racemase 40989..42131 Lawsonia intracellularis PHE/MN1-00 4060345 YP_594413.1 CDS fur NC_008011.1 42140 42592 R Fe2+/Zn2+ uptake regulation proteins complement(42140..42592) Lawsonia intracellularis PHE/MN1-00 4060312 YP_594414.1 CDS rfaF NC_008011.1 42906 43955 R ADP-heptose:LPS heptosyltransferase II complement(42906..43955) Lawsonia intracellularis PHE/MN1-00 4059947 YP_594415.1 CDS LI0037 NC_008011.1 44293 44535 R transcriptional regulator complement(44293..44535) Lawsonia intracellularis PHE/MN1-00 4059487 YP_594416.1 CDS LI0038 NC_008011.1 44534 45043 D exported nuclease 44534..45043 Lawsonia intracellularis PHE/MN1-00 4059488 YP_594417.1 CDS LI0039 NC_008011.1 45343 45816 D hypothetical protein 45343..45816 Lawsonia intracellularis PHE/MN1-00 4059489 YP_594418.1 CDS LI0040 NC_008011.1 <45849 47372 D hypothetical protein <45849..47372 Lawsonia intracellularis PHE/MN1-00 4059490 YP_594419.1 CDS LI0041 NC_008011.1 47683 49611 D hypothetical protein 47683..49611 Lawsonia intracellularis PHE/MN1-00 4059491 YP_594420.1 CDS LI0042 NC_008011.1 49861 50334 D hypothetical protein 49861..50334 Lawsonia intracellularis PHE/MN1-00 4059492 YP_594421.1 CDS LI0043 NC_008011.1 50406 53108 D hypothetical protein 50406..53108 Lawsonia intracellularis PHE/MN1-00 4060033 YP_594422.1 CDS mdoB NC_008011.1 53869 55779 R hypothetical protein complement(53869..55779) Lawsonia intracellularis PHE/MN1-00 4060147 YP_594423.1 CDS LI0045 NC_008011.1 56748 59387 D hypothetical protein 56748..59387 Lawsonia intracellularis PHE/MN1-00 4060034 YP_594424.1 CDS LI0046 NC_008011.1 60142 60534 D hypothetical protein 60142..60534 Lawsonia intracellularis PHE/MN1-00 4060035 YP_594425.1 CDS secF NC_008011.1 61583 62695 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(61583..62695) Lawsonia intracellularis PHE/MN1-00 4059637 YP_594426.1 CDS secD NC_008011.1 62698 64281 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(62698..64281) Lawsonia intracellularis PHE/MN1-00 4059636 YP_594427.1 CDS yajC NC_008011.1 64432 64770 R preprotein translocase subunit YajC complement(64432..64770) Lawsonia intracellularis PHE/MN1-00 4059617 YP_594428.1 CDS LI0050 NC_008011.1 65816 69043 R uncharacterized protein involved in outer membrane biogenesis complement(65816..69043) Lawsonia intracellularis PHE/MN1-00 4060036 YP_594429.1 CDS uvrD NC_008011.1 69095 72304 R ATP-dependent exoDNAse beta subunit complement(69095..72304) Lawsonia intracellularis PHE/MN1-00 4059609 YP_594430.1 CDS pfp NC_008011.1 72270 73637 R catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate; diphosphate--fructose-6-phosphate 1-phosphotransferase complement(72270..73637) Lawsonia intracellularis PHE/MN1-00 4060031 YP_594431.1 CDS LI0053 NC_008011.1 74229 74561 D hypothetical protein 74229..74561 Lawsonia intracellularis PHE/MN1-00 4060037 YP_594432.1 CDS LI0054 NC_008011.1 74909 75781 R rRNA methylases complement(74909..75781) Lawsonia intracellularis PHE/MN1-00 4060038 YP_594433.1 CDS mltD NC_008011.1 75939 77606 D membrane-bound lytic murein transglycosylase D (MltD) 75939..77606 Lawsonia intracellularis PHE/MN1-00 4060122 YP_594434.1 CDS LI0056 NC_008011.1 77677 78435 R nitrate ABC transporter, permease (nrtB-1) complement(77677..78435) Lawsonia intracellularis PHE/MN1-00 4060039 YP_594435.1 CDS LI0057 NC_008011.1 78432 79178 R nitrate ABC transporter, ATP-binding protein (nrtC-1) complement(78432..79178) Lawsonia intracellularis PHE/MN1-00 4060040 YP_594436.1 CDS LI0058 NC_008011.1 79175 80086 R thiamine biosynthesis protein complement(79175..80086) Lawsonia intracellularis PHE/MN1-00 4060041 YP_594437.1 CDS LI0059 NC_008011.1 80428 80937 D hypothetical protein 80428..80937 Lawsonia intracellularis PHE/MN1-00 4060042 YP_594438.1 CDS glpR NC_008011.1 81700 82470 D transcriptional regulators of sugar metabolism 81700..82470 Lawsonia intracellularis PHE/MN1-00 4060220 YP_594439.1 CDS LI0061 NC_008011.1 82557 82877 R hypothetical protein complement(82557..82877) Lawsonia intracellularis PHE/MN1-00 4060043 YP_594440.1 CDS ybeN NC_008011.1 83393 84085 R nicotinic acid mononucleotide adenylyltransferase complement(83393..84085) Lawsonia intracellularis PHE/MN1-00 4059618 YP_594441.1 CDS LI0063 NC_008011.1 84629 85216 D hypothetical protein 84629..85216 Lawsonia intracellularis PHE/MN1-00 4060044 YP_594442.1 CDS LI0064 NC_008011.1 85844 86242 D transcriptional regulator 85844..86242 Lawsonia intracellularis PHE/MN1-00 4060045 YP_594443.1 CDS LI0065 NC_008011.1 86420 87169 R Outer membrane lipoprotein-sorting protein complement(86420..87169) Lawsonia intracellularis PHE/MN1-00 4060046 YP_594444.1 CDS ftsK NC_008011.1 87173 89860 R DNA segregation ATPase FtsK/SpoIIIE and related proteins complement(87173..89860) Lawsonia intracellularis PHE/MN1-00 4059757 YP_594445.1 CDS LI0067 NC_008011.1 89937 90494 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(89937..90494) Lawsonia intracellularis PHE/MN1-00 4060047 YP_594446.1 CDS engB NC_008011.1 90801 91409 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 90801..91409 Lawsonia intracellularis PHE/MN1-00 4060048 YP_594447.1 CDS LI0069 NC_008011.1 92957 93616 D hypothetical protein 92957..93616 Lawsonia intracellularis PHE/MN1-00 4060049 YP_594448.1 CDS LI0070 NC_008011.1 93731 94156 D hypothetical protein 93731..94156 Lawsonia intracellularis PHE/MN1-00 4060050 YP_594449.1 CDS LI0071 NC_008011.1 94285 94833 D hypothetical protein 94285..94833 Lawsonia intracellularis PHE/MN1-00 4060051 YP_594450.1 CDS LI0072 NC_008011.1 94921 95379 D hypothetical protein 94921..95379 Lawsonia intracellularis PHE/MN1-00 4060052 YP_594451.1 CDS LI0073 NC_008011.1 95597 96073 D hypothetical protein 95597..96073 Lawsonia intracellularis PHE/MN1-00 4060269 YP_594452.1 CDS LI0074 NC_008011.1 97539 97961 R rhodanese-related sulfurtransferase complement(97539..97961) Lawsonia intracellularis PHE/MN1-00 4060270 YP_594453.1 CDS icc NC_008011.1 98193 98996 D phosphodiesterase 98193..98996 Lawsonia intracellularis PHE/MN1-00 4059666 YP_594454.1 CDS LI0076 NC_008011.1 99014 100063 D sugar ABC transporter, ATP-binding protein 99014..100063 Lawsonia intracellularis PHE/MN1-00 4060271 YP_594455.1 CDS ugpB NC_008011.1 100196 101491 D extracellular solute-binding protein 100196..101491 Lawsonia intracellularis PHE/MN1-00 4059605 YP_594456.1 CDS ugpA NC_008011.1 101554 102441 D inner membrane component of binding-protein-dependent transport system 101554..102441 Lawsonia intracellularis PHE/MN1-00 4059604 YP_594457.1 CDS LI0079 NC_008011.1 102438 103274 D inner membrane component of binding-protein-dependent transport system 102438..103274 Lawsonia intracellularis PHE/MN1-00 4060272 YP_594458.1 CDS LI0080 NC_008011.1 103384 104913 R hypothetical protein complement(103384..104913) Lawsonia intracellularis PHE/MN1-00 4060273 YP_594459.1 CDS LI0081 NC_008011.1 105205 106146 D nucleoside-diphosphate sugar epimerase 105205..106146 Lawsonia intracellularis PHE/MN1-00 4060274 YP_594460.1 CDS LI0082 NC_008011.1 106189 107283 R hypothetical protein complement(106189..107283) Lawsonia intracellularis PHE/MN1-00 4060275 YP_594461.1 CDS kpsF NC_008011.1 107298 108380 R CBS domain-containing protein complement(107298..108380) Lawsonia intracellularis PHE/MN1-00 4059678 YP_594462.1 CDS LI0084 NC_008011.1 110475 111206 R hypothetical protein complement(110475..111206) Lawsonia intracellularis PHE/MN1-00 4060276 YP_594463.1 CDS dnaK NC_008011.1 111603 112004 R molecular chaperone DnaK complement(111603..112004) Lawsonia intracellularis PHE/MN1-00 4060379 YP_594464.1 CDS LI0086 NC_008011.1 112674 113177 R beta-D-galactosidase complement(112674..113177) Lawsonia intracellularis PHE/MN1-00 4060277 YP_594465.1 CDS argD NC_008011.1 113180 114442 R catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase complement(113180..114442) Lawsonia intracellularis PHE/MN1-00 4059378 YP_594466.1 CDS dut NC_008011.1 114414 114896 R dUTPase complement(114414..114896) Lawsonia intracellularis PHE/MN1-00 4059298 YP_594467.1 CDS folE NC_008011.1 115144 115653 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 115144..115653 Lawsonia intracellularis PHE/MN1-00 4059750 YP_594468.1 CDS LI0090 NC_008011.1 115673 116482 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 115673..116482 Lawsonia intracellularis PHE/MN1-00 4060278 YP_594469.1 CDS eno NC_008011.1 116596 117897 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 116596..117897 Lawsonia intracellularis PHE/MN1-00 4059300 YP_594470.1 CDS rfaF/rfaQ NC_008011.1 117911 118954 R ADP-heptose:LPS heptosyltransferase complement(117911..118954) Lawsonia intracellularis PHE/MN1-00 4059949 YP_594471.1 CDS LI0093 NC_008011.1 119487 120482 D hypothetical protein 119487..120482 Lawsonia intracellularis PHE/MN1-00 4060279 YP_594472.1 CDS pfk NC_008011.1 120488 121714 D fructose-2,6-bisphosphatase 120488..121714 Lawsonia intracellularis PHE/MN1-00 4060030 YP_594473.1 CDS LI0095 NC_008011.1 121739 123019 R CheY-like receiver complement(121739..123019) Lawsonia intracellularis PHE/MN1-00 4060280 YP_594474.1 CDS LI0096 NC_008011.1 123089 123490 R hypothetical protein complement(123089..123490) Lawsonia intracellularis PHE/MN1-00 4060281 YP_594475.1 CDS corA NC_008011.1 124343 125278 R CorA, CorA-like Mg2+ transporter protein complement(124343..125278) Lawsonia intracellularis PHE/MN1-00 4060435 YP_594476.1 CDS LI0098 NC_008011.1 125579 126076 D hypothetical protein 125579..126076 Lawsonia intracellularis PHE/MN1-00 4060282 YP_594477.1 CDS argC NC_008011.1 126080 127141 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(126080..127141) Lawsonia intracellularis PHE/MN1-00 4059377 YP_594478.1 CDS LI0100 NC_008011.1 127145 127495 R hypothetical protein complement(127145..127495) Lawsonia intracellularis PHE/MN1-00 4060283 YP_594479.1 CDS dgkA NC_008011.1 127796 128161 R diacylglycerol kinase complement(127796..128161) Lawsonia intracellularis PHE/MN1-00 4060373 YP_594480.1 CDS polB NC_008011.1 128189 130795 R DNA polymerase I complement(128189..130795) Lawsonia intracellularis PHE/MN1-00 4060003 YP_594481.1 CDS LI0103 NC_008011.1 131168 132442 D hypothetical protein 131168..132442 Lawsonia intracellularis PHE/MN1-00 4060284 YP_594482.1 CDS LI0104 NC_008011.1 132452 133093 D hypothetical protein 132452..133093 Lawsonia intracellularis PHE/MN1-00 4060285 YP_594483.1 CDS LI0105 NC_008011.1 133237 134181 D hypothetical protein 133237..134181 Lawsonia intracellularis PHE/MN1-00 4060286 YP_594484.1 CDS ilv NC_008011.1 134353 136017 R catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis; acetolactate synthase complement(134353..136017) Lawsonia intracellularis PHE/MN1-00 4059668 YP_594485.1 CDS LI0107 NC_008011.1 136036 136965 R permease complement(136036..136965) Lawsonia intracellularis PHE/MN1-00 4060287 YP_594486.1 CDS dapA NC_008011.1 137267 138253 R dihydrodipicolinate synthase/N-acetylneuraminate lyase complement(137267..138253) Lawsonia intracellularis PHE/MN1-00 4060445 YP_594487.1 CDS LI0109 NC_008011.1 138738 139481 D hypothetical protein 138738..139481 Lawsonia intracellularis PHE/MN1-00 4060229 YP_594488.1 CDS smf NC_008011.1 139486 140751 D DNA uptake Rossmann fold nucleotide-binding protein 139486..140751 Lawsonia intracellularis PHE/MN1-00 4059801 YP_594489.1 CDS LI0111 NC_008011.1 140818 141759 D site-specific recombinase XerC 140818..141759 Lawsonia intracellularis PHE/MN1-00 4060230 YP_594490.1 CDS LI0112 NC_008011.1 141824 142765 R hypothetical protein complement(141824..142765) Lawsonia intracellularis PHE/MN1-00 4060231 YP_594491.1 CDS engA NC_008011.1 142958 144319 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(142958..144319) Lawsonia intracellularis PHE/MN1-00 4060232 YP_594492.1 CDS serS NC_008011.1 144414 145688 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(144414..145688) Lawsonia intracellularis PHE/MN1-00 4059643 YP_594493.1 CDS LI0115 NC_008011.1 145952 146530 D hypothetical protein 145952..146530 Lawsonia intracellularis PHE/MN1-00 4060233 YP_594494.1 CDS LI0116 NC_008011.1 146548 147627 D TPR repeat-containing protein 146548..147627 Lawsonia intracellularis PHE/MN1-00 4060234 YP_594495.1 CDS cysG NC_008011.1 147699 149210 D siroheme synthase 147699..149210 Lawsonia intracellularis PHE/MN1-00 4060441 YP_594496.1 CDS purN NC_008011.1 149239 149922 D phosphoribosylglycinamide formyltransferase 149239..149922 Lawsonia intracellularis PHE/MN1-00 4059961 YP_594497.1 CDS msrA NC_008011.1 149998 150498 R peptide methionine sulfoxide reductase complement(149998..150498) Lawsonia intracellularis PHE/MN1-00 4060073 YP_594498.1 CDS LI0120 NC_008011.1 150473 150880 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; a fusion protein of this enzyme with MsrA and thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; methionine sulfoxide reductase B complement(150473..150880) Lawsonia intracellularis PHE/MN1-00 4060235 YP_594499.1 CDS pepQ NC_008011.1 150925 151581 R Xaa-Pro aminopeptidase complement(150925..151581) Lawsonia intracellularis PHE/MN1-00 4060028 YP_594500.1 CDS LI0122 NC_008011.1 152230 152988 D cytochrome c biogenesis protein 152230..152988 Lawsonia intracellularis PHE/MN1-00 4060236 YP_594501.1 CDS lacA NC_008011.1 153127 153696 R maltose O-acetyltransferase complement(153127..153696) Lawsonia intracellularis PHE/MN1-00 4059680 YP_594502.1 CDS cbpA NC_008011.1 154211 155119 D DnaJ-class molecular chaperone 154211..155119 Lawsonia intracellularis PHE/MN1-00 4060408 YP_594503.1 CDS LI0125 NC_008011.1 155138 155449 D hypothetical protein 155138..155449 Lawsonia intracellularis PHE/MN1-00 4060237 YP_594504.1 CDS clpB NC_008011.1 155540 158173 D ATPases with chaperone activity, ATP-binding subunit 155540..158173 Lawsonia intracellularis PHE/MN1-00 4060425 YP_594505.1 CDS glnQ NC_008011.1 158235 158993 R ABC-type polar amino acid transport system, ATPase component complement(158235..158993) Lawsonia intracellularis PHE/MN1-00 4060214 YP_594506.1 CDS glnP NC_008011.1 158962 159747 R ABC-type amino acid transport system, permease component complement(158962..159747) Lawsonia intracellularis PHE/MN1-00 4060211 YP_594507.1 CDS LI0129 NC_008011.1 159798 160547 R amino acid ABC transporter substrate-binding protein complement(159798..160547) Lawsonia intracellularis PHE/MN1-00 4060238 YP_594508.1 CDS hisJ NC_008011.1 160881 161474 D histidinol phosphatase and related phosphatases 160881..161474 Lawsonia intracellularis PHE/MN1-00 4059685 YP_594509.1 CDS folC NC_008011.1 161575 162882 D folylpolyglutamate synthase 161575..162882 Lawsonia intracellularis PHE/MN1-00 4059749 YP_594510.1 CDS selA NC_008011.1 162904 164340 D catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 162904..164340 Lawsonia intracellularis PHE/MN1-00 4059640 YP_594511.1 CDS LI0133 NC_008011.1 164510 164863 D hypothetical protein 164510..164863 Lawsonia intracellularis PHE/MN1-00 4060239 YP_594512.1 CDS LI0134 NC_008011.1 164954 166084 D polymerase 164954..166084 Lawsonia intracellularis PHE/MN1-00 4060240 YP_594513.1 CDS LI0135 NC_008011.1 166090 167793 D hypothetical protein 166090..167793 Lawsonia intracellularis PHE/MN1-00 4060241 YP_594514.1 CDS LI0136 NC_008011.1 169098 169745 D hypothetical protein 169098..169745 Lawsonia intracellularis PHE/MN1-00 4060242 YP_594515.1 CDS LI0137 NC_008011.1 170015 170803 R integral membrane protein complement(170015..170803) Lawsonia intracellularis PHE/MN1-00 4060243 YP_594516.1 CDS LI0138 NC_008011.1 171157 171543 R hypothetical protein complement(171157..171543) Lawsonia intracellularis PHE/MN1-00 4060244 YP_594517.1 CDS LI0139 NC_008011.1 171577 172059 R hypothetical protein complement(171577..172059) Lawsonia intracellularis PHE/MN1-00 4060245 YP_594518.1 CDS LI0140 NC_008011.1 172266 173522 R glycosyltransferase complement(172266..173522) Lawsonia intracellularis PHE/MN1-00 4060246 YP_594519.1 CDS nodB NC_008011.1 173721 174680 D xylanase/chitin deacetylase 173721..174680 Lawsonia intracellularis PHE/MN1-00 4060060 YP_594520.1 CDS LI0142 NC_008011.1 178242 179129 D hypothetical protein 178242..179129 Lawsonia intracellularis PHE/MN1-00 4060247 YP_594521.1 CDS LI0143 NC_008011.1 180054 180455 R hypothetical protein complement(180054..180455) Lawsonia intracellularis PHE/MN1-00 4060248 YP_594522.1 CDS LI0144 NC_008011.1 180718 181446 R SAM-dependent methyltransferases complement(180718..181446) Lawsonia intracellularis PHE/MN1-00 4059857 YP_594523.1 CDS typA/bipA NC_008011.1 182088 183926 D GTP-binding protein LepA 182088..183926 Lawsonia intracellularis PHE/MN1-00 4059508 YP_594524.1 CDS LI0146 NC_008011.1 183980 185080 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(183980..185080) Lawsonia intracellularis PHE/MN1-00 4059858 YP_594525.1 CDS LI0147 NC_008011.1 185352 185810 D Outer membrane lipoprotein 185352..185810 Lawsonia intracellularis PHE/MN1-00 4059859 YP_594526.1 CDS lon NC_008011.1 185906 188398 R ATP-dependent protease complement(185906..188398) Lawsonia intracellularis PHE/MN1-00 4059661 YP_594527.1 CDS radC NC_008011.1 188436 189116 R DNA repair proteins complement(188436..189116) Lawsonia intracellularis PHE/MN1-00 4059937 YP_594528.1 CDS LI0150 NC_008011.1 189211 190188 R hypothetical protein complement(189211..190188) Lawsonia intracellularis PHE/MN1-00 4059860 YP_594529.1 CDS LI0151 NC_008011.1 190209 190736 R hypothetical protein complement(190209..190736) Lawsonia intracellularis PHE/MN1-00 4059861 YP_594530.1 CDS leuS NC_008011.1 190747 193254 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(190747..193254) Lawsonia intracellularis PHE/MN1-00 4059645 YP_594531.1 CDS nusB NC_008011.1 193265 193750 R transcription termination factor complement(193265..193750) Lawsonia intracellularis PHE/MN1-00 4060069 YP_594532.1 CDS ribH NC_008011.1 193760 194233 R riboflavin synthase beta-chain complement(193760..194233) Lawsonia intracellularis PHE/MN1-00 4059900 YP_594533.1 CDS ribA NC_008011.1 194320 >195588 R GTP cyclohydrolase II complement(194320..>195588) Lawsonia intracellularis PHE/MN1-00 4059896 YP_594534.1 CDS ribE NC_008011.1 195573 196238 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(195573..196238) Lawsonia intracellularis PHE/MN1-00 4059898 YP_594535.1 CDS ribD NC_008011.1 196242 197390 R pyrimidine reductase, riboflavin biosynthesis complement(196242..197390) Lawsonia intracellularis PHE/MN1-00 4059897 YP_594536.1 CDS glyA NC_008011.1 197926 199164 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(197926..199164) Lawsonia intracellularis PHE/MN1-00 4060225 YP_594537.1 CDS fabF/fabB NC_008011.1 199233 200483 R 3-oxoacyl-ACP synthase complement(199233..200483) Lawsonia intracellularis PHE/MN1-00 4059303 YP_594538.1 CDS fabG NC_008011.1 200903 201646 R 3-oxoacyl-ACP reductase complement(200903..201646) Lawsonia intracellularis PHE/MN1-00 4059304 YP_594539.1 CDS fabH NC_008011.1 201755 202759 R 3-oxoacyl-ACP synthase complement(201755..202759) Lawsonia intracellularis PHE/MN1-00 4059305 YP_594540.1 CDS plsX NC_008011.1 202841 203884 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX complement(202841..203884) Lawsonia intracellularis PHE/MN1-00 4060000 YP_594541.1 CDS LI0164 NC_008011.1 204107 204643 R metal-binding protein complement(204107..204643) Lawsonia intracellularis PHE/MN1-00 4059862 YP_594542.1 CDS mutY NC_008011.1 204755 205846 R A/G-specific adenine glycosylase complement(204755..205846) Lawsonia intracellularis PHE/MN1-00 4060085 YP_594543.1 CDS ppiB NC_008011.1 205977 206483 D peptidyl-prolyl cis-trans isomerase 205977..206483 Lawsonia intracellularis PHE/MN1-00 4059974 YP_594544.1 CDS LI0167 NC_008011.1 206826 207434 R peptidyl-prolyl cis-trans isomerase complement(206826..207434) Lawsonia intracellularis PHE/MN1-00 4059863 YP_594545.1 CDS LI0168 NC_008011.1 207522 210743 R SNF2 family DNA/RNA helicase complement(207522..210743) Lawsonia intracellularis PHE/MN1-00 4059864 YP_594546.1 CDS oppA NC_008011.1 <211599 >213256 D ABC-type dipeptide transport system, periplasmic component <211599..>213256 Lawsonia intracellularis PHE/MN1-00 4060013 YP_594547.1 CDS relA NC_008011.1 213386 215581 D guanosine polyphosphate pyrophosphohydrolases/synthetases 213386..215581 Lawsonia intracellularis PHE/MN1-00 4059945 YP_594548.1 CDS LI0171 NC_008011.1 215599 216006 R hypothetical protein complement(215599..216006) Lawsonia intracellularis PHE/MN1-00 4059865 YP_594549.1 CDS LI0172 NC_008011.1 216601 217899 R hypothetical protein complement(216601..217899) Lawsonia intracellularis PHE/MN1-00 4059866 YP_594550.1 CDS LI0173 NC_008011.1 <218703 219869 D prophage DLP12 integrase <218703..219869 Lawsonia intracellularis PHE/MN1-00 4059867 YP_594551.1 CDS LI0174 NC_008011.1 219859 220869 D hypothetical protein 219859..220869 Lawsonia intracellularis PHE/MN1-00 4059868 YP_594552.1 CDS LI0175 NC_008011.1 221210 222874 D hypothetical protein 221210..222874 Lawsonia intracellularis PHE/MN1-00 4059869 YP_594553.1 CDS LI0176 NC_008011.1 222965 223357 D hypothetical protein 222965..223357 Lawsonia intracellularis PHE/MN1-00 4059870 YP_594554.1 CDS LI0177 NC_008011.1 223987 224532 D hypothetical protein 223987..224532 Lawsonia intracellularis PHE/MN1-00 4059871 YP_594555.1 CDS LI0178 NC_008011.1 224690 225184 D hypothetical protein 224690..225184 Lawsonia intracellularis PHE/MN1-00 4059872 YP_594556.1 CDS tetW NC_008011.1 225939 227858 R ribosomal protection tetracycline resistance protein complement(225939..227858) Lawsonia intracellularis PHE/MN1-00 4059813 YP_594557.1 CDS LI0180 NC_008011.1 228343 229257 D hypothetical protein 228343..229257 Lawsonia intracellularis PHE/MN1-00 4059873 YP_594558.1 CDS LI0181 NC_008011.1 229471 230256 D endonuclease I 229471..230256 Lawsonia intracellularis PHE/MN1-00 4059874 YP_594559.1 CDS LI0182 NC_008011.1 230232 231092 D recombination protein-phage associated 230232..231092 Lawsonia intracellularis PHE/MN1-00 4059875 YP_594560.1 CDS LI0183 NC_008011.1 231161 232363 D hypothetical protein 231161..232363 Lawsonia intracellularis PHE/MN1-00 4060170 YP_594561.1 CDS LI0184 NC_008011.1 232347 232721 D hypothetical protein 232347..232721 Lawsonia intracellularis PHE/MN1-00 4060171 YP_594562.1 CDS LI0185 NC_008011.1 232791 233741 D MoxR-like ATPases 232791..233741 Lawsonia intracellularis PHE/MN1-00 4060172 YP_594563.1 CDS LI0186 NC_008011.1 233745 234740 D hypothetical protein 233745..234740 Lawsonia intracellularis PHE/MN1-00 4060173 YP_594564.1 CDS LI0187 NC_008011.1 234755 236347 D hypothetical protein 234755..236347 Lawsonia intracellularis PHE/MN1-00 4060174 YP_594565.1 CDS ftsH NC_008011.1 236969 238876 D ATP-dependent Zn proteases 236969..238876 Lawsonia intracellularis PHE/MN1-00 4059755 YP_594566.1 CDS folP NC_008011.1 238888 239775 D dihydropteroate synthase 238888..239775 Lawsonia intracellularis PHE/MN1-00 4059752 YP_594567.1 CDS LI0190 NC_008011.1 239839 240579 D hypothetical protein 239839..240579 Lawsonia intracellularis PHE/MN1-00 4060175 YP_594568.1 CDS LI0191 NC_008011.1 240772 241494 D hypothetical protein 240772..241494 Lawsonia intracellularis PHE/MN1-00 4060176 YP_594569.1 CDS glmM NC_008011.1 241522 242877 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 241522..242877 Lawsonia intracellularis PHE/MN1-00 4060177 YP_594570.1 CDS galU NC_008011.1 242878 243798 D UDP-glucose pyrophosphorylase 242878..243798 Lawsonia intracellularis PHE/MN1-00 4060317 YP_594571.1 CDS priA NC_008011.1 243833 246211 D primosomal protein N' 243833..246211 Lawsonia intracellularis PHE/MN1-00 4059979 YP_594572.1 CDS LI0195 NC_008011.1 247238 247885 D SAM-dependent methyltransferases 247238..247885 Lawsonia intracellularis PHE/MN1-00 4060178 YP_594573.1 CDS LI0196 NC_008011.1 247882 249495 D transport protein 247882..249495 Lawsonia intracellularis PHE/MN1-00 4060179 YP_594574.1 CDS LI0197 NC_008011.1 249535 250242 R endo-1,4-beta-xylanase complement(249535..250242) Lawsonia intracellularis PHE/MN1-00 4060180 YP_594575.1 CDS LI0198 NC_008011.1 250367 250963 R membrane protein complement(250367..250963) Lawsonia intracellularis PHE/MN1-00 4060181 YP_594576.1 CDS LI0199 NC_008011.1 250984 253005 R exoribonuclease R complement(250984..253005) Lawsonia intracellularis PHE/MN1-00 4060182 YP_594577.1 CDS purH NC_008011.1 253065 254339 R AICAR transformylase/IMP cyclohydrolase PurH complement(253065..254339) Lawsonia intracellularis PHE/MN1-00 4059955 YP_594578.1 CDS LI0201 NC_008011.1 254566 254889 D hypothetical protein 254566..254889 Lawsonia intracellularis PHE/MN1-00 4060183 YP_594579.1 CDS purA NC_008011.1 255142 256428 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 255142..256428 Lawsonia intracellularis PHE/MN1-00 4059989 YP_594580.1 CDS trmU NC_008011.1 256593 257651 D tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase 256593..257651 Lawsonia intracellularis PHE/MN1-00 4059837 YP_594581.1 CDS LI0204 NC_008011.1 257733 258917 D Fe-S oxidoreductases 257733..258917 Lawsonia intracellularis PHE/MN1-00 4060184 YP_594582.1 CDS hemB NC_008011.1 259031 260029 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 259031..260029 Lawsonia intracellularis PHE/MN1-00 4060261 YP_594583.1 CDS LI0206 NC_008011.1 260014 261327 D Fe-S oxidoreductases 260014..261327 Lawsonia intracellularis PHE/MN1-00 4060185 YP_594584.1 CDS nirD NC_008011.1 261332 261784 D transcriptional regulators 261332..261784 Lawsonia intracellularis PHE/MN1-00 4060058 YP_594585.1 CDS LI0208 NC_008011.1 261947 262936 D hypothetical protein 261947..262936 Lawsonia intracellularis PHE/MN1-00 4060186 YP_594586.1 CDS LI0209 NC_008011.1 263206 263820 D hypothetical protein 263206..263820 Lawsonia intracellularis PHE/MN1-00 4060187 YP_594587.1 CDS fliS NC_008011.1 264303 264875 R flagellin-specific chaperone FliS complement(264303..264875) Lawsonia intracellularis PHE/MN1-00 4059747 YP_594588.1 CDS fliD NC_008011.1 264907 266991 R flagellar capping protein complement(264907..266991) Lawsonia intracellularis PHE/MN1-00 4059737 YP_594589.1 CDS thrS NC_008011.1 267658 269586 D threonyl-tRNA synthetase 267658..269586 Lawsonia intracellularis PHE/MN1-00 4059823 YP_594590.1 CDS infC NC_008011.1 269654 270130 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 269654..270130 Lawsonia intracellularis PHE/MN1-00 4060188 YP_594591.1 CDS rplT NC_008011.1 270500 270853 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 270500..270853 Lawsonia intracellularis PHE/MN1-00 4059893 YP_594592.1 CDS pheS NC_008011.1 270937 271974 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 270937..271974 Lawsonia intracellularis PHE/MN1-00 4059997 YP_594593.1 CDS pheT NC_008011.1 272014 274425 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 272014..274425 Lawsonia intracellularis PHE/MN1-00 4059998 YP_594594.1 CDS LI0217 NC_008011.1 274466 274882 D transcriptional regulator 274466..274882 Lawsonia intracellularis PHE/MN1-00 4060189 YP_594595.1 CDS rpe NC_008011.1 275097 275564 D Pentose-5-phosphate-3-epimerase 275097..275564 Lawsonia intracellularis PHE/MN1-00 4059912 YP_594596.1 CDS tkt NC_008011.1 275627 277594 D transketolase 275627..277594 Lawsonia intracellularis PHE/MN1-00 4059825 YP_594597.1 CDS trmD NC_008011.1 277821 278945 D tRNA-(guanine-N1)-methyltransferase 277821..278945 Lawsonia intracellularis PHE/MN1-00 4059836 YP_594598.1 CDS rplS NC_008011.1 278981 279328 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 278981..279328 Lawsonia intracellularis PHE/MN1-00 4059891 YP_594599.1 CDS rplS NC_008011.1 279395 280069 D ribonuclease HII 279395..280069 Lawsonia intracellularis PHE/MN1-00 4059892 YP_594600.1 CDS LI0223 NC_008011.1 280089 280487 D hypothetical protein 280089..280487 Lawsonia intracellularis PHE/MN1-00 4059760 YP_594601.1 CDS LI0224 NC_008011.1 280429 281259 D methyltransferases 280429..281259 Lawsonia intracellularis PHE/MN1-00 4059761 YP_594602.1 CDS smpB NC_008011.1 281262 281729 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 281262..281729 Lawsonia intracellularis PHE/MN1-00 4059802 YP_594603.1 CDS yjjK NC_008011.1 281750 283432 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 281750..283432 Lawsonia intracellularis PHE/MN1-00 4059534 YP_594604.1 CDS fabD NC_008011.1 283562 284482 R ACP S-malonyltransferase complement(283562..284482) Lawsonia intracellularis PHE/MN1-00 4059302 YP_594605.1 CDS glpX NC_008011.1 284607 285644 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(284607..285644) Lawsonia intracellularis PHE/MN1-00 4060221 YP_594606.1 CDS argS NC_008011.1 285821 287473 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 285821..287473 Lawsonia intracellularis PHE/MN1-00 4059383 YP_594607.1 CDS LI0230 NC_008011.1 287480 288256 D hypothetical protein 287480..288256 Lawsonia intracellularis PHE/MN1-00 4059762 YP_594608.1 CDS LI0231 NC_008011.1 288273 289073 D ABC-type transport system involved in resistance to organic solvents, permease component 288273..289073 Lawsonia intracellularis PHE/MN1-00 4059763 YP_594609.1 CDS LI0232 NC_008011.1 289086 289916 D ABC-type transport system involved in resistance to organic solvents, ATPase component 289086..289916 Lawsonia intracellularis PHE/MN1-00 4059764 YP_594610.1 CDS LI0233 NC_008011.1 289932 290375 D ABC-type transport system involved in resistance to organic solvents, periplasmic component 289932..290375 Lawsonia intracellularis PHE/MN1-00 4059765 YP_594611.1 CDS LI0234 NC_008011.1 290380 291030 D ABC-type transport system involved in resistance to organic solvents, auxiliary component 290380..291030 Lawsonia intracellularis PHE/MN1-00 4059766 YP_594612.1 CDS LI0235 NC_008011.1 291031 291927 D surface lipoprotein 291031..291927 Lawsonia intracellularis PHE/MN1-00 4059767 YP_594613.1 CDS mutS NC_008011.1 292398 295079 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(292398..295079) Lawsonia intracellularis PHE/MN1-00 4060083 YP_594614.1 CDS LI0237 NC_008011.1 295534 296034 R diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases complement(295534..296034) Lawsonia intracellularis PHE/MN1-00 4059768 YP_594615.1 CDS cca NC_008011.1 296154 297827 R poly(A) polymerase complement(296154..297827) Lawsonia intracellularis PHE/MN1-00 4060409 YP_594616.1 CDS LI0239 NC_008011.1 297994 298914 R site-specific recombinase complement(297994..298914) Lawsonia intracellularis PHE/MN1-00 4059769 YP_594617.1 CDS folk NC_008011.1 299096 299647 D 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 299096..299647 Lawsonia intracellularis PHE/MN1-00 4059751 YP_594618.1 CDS uvrB NC_008011.1 300171 302201 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 300171..302201 Lawsonia intracellularis PHE/MN1-00 4059607 YP_594619.1 CDS lig NC_008011.1 302221 304269 D NAD-dependent DNA ligase 302221..304269 Lawsonia intracellularis PHE/MN1-00 4059648 YP_594620.1 CDS dapB NC_008011.1 304286 305062 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 304286..305062 Lawsonia intracellularis PHE/MN1-00 4060369 YP_594621.1 CDS nadE NC_008011.1 305063 306640 D NH(3)-dependent NAD(+) synthetase 305063..306640 Lawsonia intracellularis PHE/MN1-00 4060090 YP_594622.1 CDS hypB NC_008011.1 306735 307415 R hydrogenase accessory protein HypB complement(306735..307415) Lawsonia intracellularis PHE/MN1-00 4059701 YP_594623.1 CDS hypA NC_008011.1 307426 307782 R zinc finger protein complement(307426..307782) Lawsonia intracellularis PHE/MN1-00 4059700 YP_594624.1 CDS LI0247 NC_008011.1 308027 308794 D hypothetical protein 308027..308794 Lawsonia intracellularis PHE/MN1-00 4059770 YP_594625.1 CDS LI0248 NC_008011.1 308869 309519 D hypothetical protein 308869..309519 Lawsonia intracellularis PHE/MN1-00 4059771 YP_594626.1 CDS recN NC_008011.1 309567 311150 R DNA repair ATPase complement(309567..311150) Lawsonia intracellularis PHE/MN1-00 4059941 YP_594627.1 CDS oppC NC_008011.1 311205 312023 R ABC-type dipeptide/oligopeptide/nickel transport systems, permease components complement(311205..312023) Lawsonia intracellularis PHE/MN1-00 4060015 YP_594628.1 CDS oppB NC_008011.1 312032 313036 R ABC-type dipeptide/oligopeptide/nickel transport systems, permease components complement(312032..313036) Lawsonia intracellularis PHE/MN1-00 4060014 YP_594629.1 CDS LI0252 NC_008011.1 313191 313712 R hypothetical protein complement(313191..313712) Lawsonia intracellularis PHE/MN1-00 4059772 YP_594630.1 CDS LI0253 NC_008011.1 313725 314339 R hypothetical protein complement(313725..314339) Lawsonia intracellularis PHE/MN1-00 4059773 YP_594631.1 CDS LI0254 NC_008011.1 314561 315688 D hypothetical protein 314561..315688 Lawsonia intracellularis PHE/MN1-00 4059774 YP_594632.1 CDS LI0255 NC_008011.1 315691 316236 R hypothetical protein complement(315691..316236) Lawsonia intracellularis PHE/MN1-00 4059775 YP_594633.1 CDS LI0256 NC_008011.1 316238 317029 R hypothetical protein complement(316238..317029) Lawsonia intracellularis PHE/MN1-00 4059776 YP_594634.1 CDS dnaE NC_008011.1 317243 320752 D DNA polymerase III, alpha subunit 317243..320752 Lawsonia intracellularis PHE/MN1-00 4060376 YP_594635.1 CDS LI0258 NC_008011.1 320772 321152 D F0F1-type ATP synthase, subunit c 320772..321152 Lawsonia intracellularis PHE/MN1-00 4059777 YP_594636.1 CDS LI0259 NC_008011.1 321305 321553 R hypothetical protein complement(321305..321553) Lawsonia intracellularis PHE/MN1-00 4059778 YP_594637.1 CDS ntrY NC_008011.1 321744 323993 D Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation 321744..323993 Lawsonia intracellularis PHE/MN1-00 4060067 YP_594638.1 CDS gad NC_008011.1 324064 325572 R glutamate decarboxylase isozyme complement(324064..325572) Lawsonia intracellularis PHE/MN1-00 4060314 YP_594639.1 CDS LI0262 NC_008011.1 325627 327084 R amino acid transporters complement(325627..327084) Lawsonia intracellularis PHE/MN1-00 4059779 YP_594640.1 CDS LI0263 NC_008011.1 327353 328624 D amino acid-amine transport protein 327353..328624 Lawsonia intracellularis PHE/MN1-00 4059780 YP_594641.1 CDS rho NC_008011.1 328991 330241 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 328991..330241 Lawsonia intracellularis PHE/MN1-00 4059954 YP_594642.1 CDS LI0265 NC_008011.1 330371 331534 R cysteine sulfinate desulfinase/cysteine desulfurase complement(330371..331534) Lawsonia intracellularis PHE/MN1-00 4059781 YP_594643.1 CDS iscU NC_008011.1 331531 >332373 R NifU homolog involved in Fe-S cluster formation complement(331531..>332373) Lawsonia intracellularis PHE/MN1-00 4059670 YP_594644.1 CDS LI0267 NC_008011.1 333321 333689 R hypothetical protein complement(333321..333689) Lawsonia intracellularis PHE/MN1-00 4059782 YP_594645.1 CDS ruvC NC_008011.1 333806 334312 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(333806..334312) Lawsonia intracellularis PHE/MN1-00 4059631 YP_594646.1 CDS yebC NC_008011.1 334384 335124 R hypothetical protein complement(334384..335124) Lawsonia intracellularis PHE/MN1-00 4059620 YP_594647.1 CDS ygcA NC_008011.1 335173 335775 R 23S rRNA methylase complement(335173..335775) Lawsonia intracellularis PHE/MN1-00 4059622 YP_594648.1 CDS LI0271 NC_008011.1 335866 337446 D hypothetical protein 335866..337446 Lawsonia intracellularis PHE/MN1-00 4059783 YP_594649.1 CDS LI0272 NC_008011.1 337458 338414 D hypothetical protein 337458..338414 Lawsonia intracellularis PHE/MN1-00 4059784 YP_594650.1 CDS LI0273 NC_008011.1 338687 339097 D desulfoferrodoxin 338687..339097 Lawsonia intracellularis PHE/MN1-00 4059785 YP_594651.1 CDS LI0274 NC_008011.1 339468 340676 D uncharacterized flavoproteins 339468..340676 Lawsonia intracellularis PHE/MN1-00 4059786 YP_594652.1 CDS cyoB NC_008011.1 340816 342117 D cytochrome bd-type quinol oxidase, subunit 1 340816..342117 Lawsonia intracellularis PHE/MN1-00 4060440 YP_594653.1 CDS cyoA NC_008011.1 342150 343178 D cytochrome bd-type quinol oxidase, subunit 2 342150..343178 Lawsonia intracellularis PHE/MN1-00 4060439 YP_594654.1 CDS LI0277 NC_008011.1 343350 343829 R hypothetical protein complement(343350..343829) Lawsonia intracellularis PHE/MN1-00 4059787 YP_594655.1 CDS porA NC_008011.1 344241 347804 D pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit 344241..347804 Lawsonia intracellularis PHE/MN1-00 4060004 YP_594656.1 CDS pta NC_008011.1 347892 350012 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 347892..350012 Lawsonia intracellularis PHE/MN1-00 4059988 YP_594657.1 CDS ackA NC_008011.1 350112 351326 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 350112..351326 Lawsonia intracellularis PHE/MN1-00 4060339 YP_594658.1 CDS miaA NC_008011.1 351351 352262 R tRNA delta(2)-isopentenylpyrophosphate transferase complement(351351..352262) Lawsonia intracellularis PHE/MN1-00 4060118 YP_594659.1 CDS kdtB NC_008011.1 352309 352827 R phosphopantetheine adenylyltransferase complement(352309..352827) Lawsonia intracellularis PHE/MN1-00 4059676 YP_594660.1 CDS LI0283 NC_008011.1 352803 353375 R N6-adenine-specific methylase complement(352803..353375) Lawsonia intracellularis PHE/MN1-00 4059788 YP_594661.1 CDS LI0284 NC_008011.1 353516 355117 R RNA processing exonuclease complement(353516..355117) Lawsonia intracellularis PHE/MN1-00 4059789 YP_594662.1 CDS LI0285 NC_008011.1 355243 356610 R cell wall-associated hydrolases (invasion-associated proteins) complement(355243..356610) Lawsonia intracellularis PHE/MN1-00 4059790 YP_594663.1 CDS LI0286 NC_008011.1 356715 358055 R cell wall-associated hydrolases (invasion-associated proteins) complement(356715..358055) Lawsonia intracellularis PHE/MN1-00 4059791 YP_594664.1 CDS recD NC_008011.1 358069 360267 R exonuclease V subunit alpha complement(358069..360267) Lawsonia intracellularis PHE/MN1-00 4059939 YP_594665.1 CDS LI0288 NC_008011.1 361133 362386 D PAP2 superfamily protein 361133..362386 Lawsonia intracellularis PHE/MN1-00 4059792 YP_594666.1 CDS LI0289 NC_008011.1 362504 363340 R pirin complement(362504..363340) Lawsonia intracellularis PHE/MN1-00 4059793 YP_594667.1 CDS LI0290 NC_008011.1 363544 364893 R hypothetical protein complement(363544..364893) Lawsonia intracellularis PHE/MN1-00 4059794 YP_594668.1 CDS LI0291 NC_008011.1 365970 367550 R hypothetical protein complement(365970..367550) Lawsonia intracellularis PHE/MN1-00 4059795 YP_594669.1 CDS LI0292 NC_008011.1 367971 368636 D Svh 367971..368636 Lawsonia intracellularis PHE/MN1-00 4059796 YP_594670.1 CDS fumB NC_008011.1 369577 370143 R fumarate hydratase complement(369577..370143) Lawsonia intracellularis PHE/MN1-00 4060311 YP_594671.1 CDS fumA NC_008011.1 370169 371014 R Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; fumarate hydratase complement(370169..371014) Lawsonia intracellularis PHE/MN1-00 4060310 YP_594672.1 CDS LI0295 NC_008011.1 371279 371884 R hypothetical protein complement(371279..371884) Lawsonia intracellularis PHE/MN1-00 4059797 YP_594673.1 CDS purM NC_008011.1 372325 373374 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(372325..373374) Lawsonia intracellularis PHE/MN1-00 4059960 YP_594674.1 CDS LI0297 NC_008011.1 373444 373821 D hypothetical protein 373444..373821 Lawsonia intracellularis PHE/MN1-00 4059798 YP_594675.1 CDS LI0298 NC_008011.1 373843 374799 D hypothetical protein 373843..374799 Lawsonia intracellularis PHE/MN1-00 4060288 YP_594676.1 CDS glyS NC_008011.1 375220 377307 R glycyl-tRNA synthetase, beta subunit complement(375220..377307) Lawsonia intracellularis PHE/MN1-00 4060227 YP_594677.1 CDS glyQ NC_008011.1 377313 378197 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(377313..378197) Lawsonia intracellularis PHE/MN1-00 4060226 YP_594678.1 CDS recO NC_008011.1 378253 379002 R hypothetical protein complement(378253..379002) Lawsonia intracellularis PHE/MN1-00 4059942 YP_594679.1 CDS LI0302 NC_008011.1 379007 380026 R hypothetical protein complement(379007..380026) Lawsonia intracellularis PHE/MN1-00 4060289 YP_594680.1 CDS ppi NC_008011.1 380045 380971 R parvulin-like peptidyl-prolyl isomerase complement(380045..380971) Lawsonia intracellularis PHE/MN1-00 4060012 YP_594681.1 CDS LI0304 NC_008011.1 381141 382058 R parvulin-like peptidyl-prolyl isomerase complement(381141..382058) Lawsonia intracellularis PHE/MN1-00 4060290 YP_594682.1 CDS LI0305 NC_008011.1 382096 385563 R transcription-repair coupling factor complement(382096..385563) Lawsonia intracellularis PHE/MN1-00 4060291 YP_594683.1 CDS LI0306 NC_008011.1 385645 387228 R integral membrane protein complement(385645..387228) Lawsonia intracellularis PHE/MN1-00 4060292 YP_594684.1 CDS greA NC_008011.1 387513 387986 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 387513..387986 Lawsonia intracellularis PHE/MN1-00 4060253 YP_594685.1 CDS LI0308 NC_008011.1 388048 389358 D 2-methylthioadenine synthetase 388048..389358 Lawsonia intracellularis PHE/MN1-00 4060293 YP_594686.1 CDS yicC NC_008011.1 389463 390344 D hypothetical protein 389463..390344 Lawsonia intracellularis PHE/MN1-00 4059532 YP_594687.1 CDS gmk NC_008011.1 390597 391235 D guanylate kinase 390597..391235 Lawsonia intracellularis PHE/MN1-00 4060249 YP_594688.1 CDS pyrF NC_008011.1 391242 391931 D orotidine-5'-phosphate decarboxylase 391242..391931 Lawsonia intracellularis PHE/MN1-00 4059969 YP_594689.1 CDS LI0312 NC_008011.1 392001 392819 D TPR repeat-containing protein 392001..392819 Lawsonia intracellularis PHE/MN1-00 4060294 YP_594690.1 CDS recJ NC_008011.1 392879 394585 D single-stranded DNA-specific exonuclease 392879..394585 Lawsonia intracellularis PHE/MN1-00 4059940 YP_594691.1 CDS pepP NC_008011.1 394647 395873 R Xaa-Pro aminopeptidase complement(394647..395873) Lawsonia intracellularis PHE/MN1-00 4060027 YP_594692.1 CDS LI0315 NC_008011.1 396014 396430 D CoA-binding protein 396014..396430 Lawsonia intracellularis PHE/MN1-00 4060295 YP_594693.1 CDS LI0316 NC_008011.1 396615 397526 D DnaJ-class molecular chaperone 396615..397526 Lawsonia intracellularis PHE/MN1-00 4060296 YP_594694.1 CDS LI0317 NC_008011.1 397583 398272 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 397583..398272 Lawsonia intracellularis PHE/MN1-00 4060297 YP_594695.1 CDS LI0318 NC_008011.1 398358 399626 R hypothetical protein complement(398358..399626) Lawsonia intracellularis PHE/MN1-00 4060298 YP_594696.1 CDS LI0319 NC_008011.1 399629 400849 R ADP-heptose:LPS heptosyltransferase complement(399629..400849) Lawsonia intracellularis PHE/MN1-00 4060299 YP_594697.1 CDS cysG NC_008011.1 401285 401962 D siroheme synthase 401285..401962 Lawsonia intracellularis PHE/MN1-00 4060442 YP_594698.1 CDS resC NC_008011.1 401949 402839 D ABC-type transport system involved in cytochrome c biogenesis, permease component 401949..402839 Lawsonia intracellularis PHE/MN1-00 4059946 YP_594699.1 CDS hemA NC_008011.1 402814 404079 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 402814..404079 Lawsonia intracellularis PHE/MN1-00 4060260 YP_594700.1 CDS LI0323 NC_008011.1 404208 405515 D Signal renition particle GTPase 404208..405515 Lawsonia intracellularis PHE/MN1-00 4060300 YP_594701.1 CDS thiE NC_008011.1 405585 406238 D thiamine monophosphate synthase 405585..406238 Lawsonia intracellularis PHE/MN1-00 4059818 YP_594702.1 CDS gltD NC_008011.1 406369 407796 R NADPH-dependent glutamate synthase beta chain and related oxidoreductases complement(406369..407796) Lawsonia intracellularis PHE/MN1-00 4060222 YP_594703.1 CDS LI0326 NC_008011.1 408049 408975 D SAM-dependent methyltransferase 408049..408975 Lawsonia intracellularis PHE/MN1-00 4060301 YP_594704.1 CDS LI0327 NC_008011.1 409616 410542 R hypothetical protein complement(409616..410542) Lawsonia intracellularis PHE/MN1-00 4060302 YP_594705.1 CDS LI0328 NC_008011.1 410586 411035 R hypothetical protein complement(410586..411035) Lawsonia intracellularis PHE/MN1-00 4060303 YP_594706.1 CDS glgX NC_008011.1 411409 413466 D Glyen debranching enzyme 411409..413466 Lawsonia intracellularis PHE/MN1-00 4060325 YP_594707.1 CDS LI0330 NC_008011.1 413485 414825 D glycosyltransferase 413485..414825 Lawsonia intracellularis PHE/MN1-00 4060304 YP_594708.1 CDS amyA NC_008011.1 414828 416114 D alpha-amylase 414828..416114 Lawsonia intracellularis PHE/MN1-00 4060347 YP_594709.1 CDS glgP NC_008011.1 416124 420386 D carbohydrate phosphorylase family protein 416124..420386 Lawsonia intracellularis PHE/MN1-00 4060324 YP_594710.1 CDS argB NC_008011.1 420460 421350 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(420460..421350) Lawsonia intracellularis PHE/MN1-00 4059376 YP_594711.1 CDS hslU NC_008011.1 421371 422672 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(421371..422672) Lawsonia intracellularis PHE/MN1-00 4059689 YP_594712.1 CDS livF NC_008011.1 422757 423464 R branched chain amino acid ABC transporter, ATP-binding protein complement(422757..423464) Lawsonia intracellularis PHE/MN1-00 4059650 YP_594713.1 CDS livG NC_008011.1 423517 424278 R branched chain amino acid ABC transporter, ATP-binding protein complement(423517..424278) Lawsonia intracellularis PHE/MN1-00 4059652 YP_594714.1 CDS livM NC_008011.1 424288 425274 R branched chain amino acid ABC transporter, permease complement(424288..425274) Lawsonia intracellularis PHE/MN1-00 4059656 YP_594715.1 CDS livH NC_008011.1 425271 426173 R branched chain amino acid ABC transporter, permease complement(425271..426173) Lawsonia intracellularis PHE/MN1-00 4059654 YP_594716.1 CDS LI0339 NC_008011.1 426224 427348 R ABC-type branched-chain amino acid transport systems, periplasmic component complement(426224..427348) Lawsonia intracellularis PHE/MN1-00 4060305 YP_594717.1 CDS LI0340 NC_008011.1 427714 428691 D hypothetical protein 427714..428691 Lawsonia intracellularis PHE/MN1-00 4060306 YP_594718.1 CDS LI0341 NC_008011.1 428956 429660 D hypothetical protein 428956..429660 Lawsonia intracellularis PHE/MN1-00 4059415 YP_594719.1 CDS leuB NC_008011.1 429818 430519 D Rossmann fold nucleotide-binding protein 429818..430519 Lawsonia intracellularis PHE/MN1-00 4059644 YP_594720.1 CDS codA NC_008011.1 430612 431100 D cytosine/adenosine deaminases 430612..431100 Lawsonia intracellularis PHE/MN1-00 4060431 YP_594721.1 CDS LI0344 NC_008011.1 431319 431606 D hypothetical protein 431319..431606 Lawsonia intracellularis PHE/MN1-00 4059416 YP_594722.1 CDS LI0345 NC_008011.1 431805 432596 D SAM-dependent methyltransferases 431805..432596 Lawsonia intracellularis PHE/MN1-00 4059417 YP_594723.1 CDS htrA NC_008011.1 433193 434617 R trypsin domain/PDZ domain-containing protein complement(433193..434617) Lawsonia intracellularis PHE/MN1-00 4059692 YP_594724.1 CDS flgE NC_008011.1 434818 437232 R flagellar hook protein FlgE complement(434818..437232) Lawsonia intracellularis PHE/MN1-00 4059721 YP_594725.1 CDS flgE NC_008011.1 437383 438891 R flagellar hook protein FlgE complement(437383..438891) Lawsonia intracellularis PHE/MN1-00 4059722 YP_594726.1 CDS purC NC_008011.1 439256 440152 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 439256..440152 Lawsonia intracellularis PHE/MN1-00 4059991 YP_594727.1 CDS fabI NC_008011.1 440193 440957 D enoyl-ACP reductase 440193..440957 Lawsonia intracellularis PHE/MN1-00 4059306 YP_594728.1 CDS mdh NC_008011.1 441137 442456 D malate dehydrogenase 441137..442456 Lawsonia intracellularis PHE/MN1-00 4060146 YP_594729.1 CDS rpsF NC_008011.1 442654 442971 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 442654..442971 Lawsonia intracellularis PHE/MN1-00 4059418 YP_594730.1 CDS rplI NC_008011.1 443247 443768 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 443247..443768 Lawsonia intracellularis PHE/MN1-00 4059881 YP_594731.1 CDS recQ NC_008011.1 443830 445194 D replicative DNA helicase 443830..445194 Lawsonia intracellularis PHE/MN1-00 4059943 YP_594732.1 CDS LI0355 NC_008011.1 445449 446039 R rRNA methylases complement(445449..446039) Lawsonia intracellularis PHE/MN1-00 4059419 YP_594733.1 CDS LI0356 NC_008011.1 446089 448086 R ABC transporter ATPase complement(446089..448086) Lawsonia intracellularis PHE/MN1-00 4059420 YP_594734.1 CDS pcm NC_008011.1 448090 448959 R protein-L-isoaspartate carboxylmethyltransferase complement(448090..448959) Lawsonia intracellularis PHE/MN1-00 4060023 YP_594735.1 CDS LI0358 NC_008011.1 449124 451136 D asmA protein 449124..451136 Lawsonia intracellularis PHE/MN1-00 4059421 YP_594736.1 CDS mgtE NC_008011.1 451158 452531 R Mg2+/Co2+ transporter complement(451158..452531) Lawsonia intracellularis PHE/MN1-00 4060117 YP_594737.1 CDS nadC NC_008011.1 452761 453651 D nicotinate-nucleotide pyrophosphorylase 452761..453651 Lawsonia intracellularis PHE/MN1-00 4060089 YP_594738.1 CDS LI0361 NC_008011.1 453648 454703 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 453648..454703 Lawsonia intracellularis PHE/MN1-00 4059422 YP_594739.1 CDS nadB NC_008011.1 454752 456335 D aspartate oxidase 454752..456335 Lawsonia intracellularis PHE/MN1-00 4060088 YP_594740.1 CDS LI0363 NC_008011.1 456390 456695 R integral membrane protein complement(456390..456695) Lawsonia intracellularis PHE/MN1-00 4059423 YP_594741.1 CDS gph NC_008011.1 456801 457475 R phosphatases complement(456801..457475) Lawsonia intracellularis PHE/MN1-00 4060251 YP_594742.1 CDS LI0365 NC_008011.1 457964 458686 R DNA uptake lipoprotein complement(457964..458686) Lawsonia intracellularis PHE/MN1-00 4059424 YP_594743.1 CDS trxB NC_008011.1 458692 459618 R thioredoxin reductase complement(458692..459618) Lawsonia intracellularis PHE/MN1-00 4059503 YP_594744.1 CDS trxA NC_008011.1 459615 459938 R Thiol-disulfide isomerase and thioredoxins complement(459615..459938) Lawsonia intracellularis PHE/MN1-00 4059502 YP_594745.1 CDS ygjD NC_008011.1 460064 461131 R metal-dependent proteases with chaperone activity complement(460064..461131) Lawsonia intracellularis PHE/MN1-00 4059623 YP_594746.1 CDS fbp NC_008011.1 461235 462242 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(461235..462242) Lawsonia intracellularis PHE/MN1-00 4059309 YP_594747.1 CDS LI0370 NC_008011.1 462356 463225 R hypothetical protein complement(462356..463225) Lawsonia intracellularis PHE/MN1-00 4059425 YP_594748.1 CDS LI0371 NC_008011.1 463255 464136 R hypothetical protein complement(463255..464136) Lawsonia intracellularis PHE/MN1-00 4059426 YP_594749.1 CDS LI0372 NC_008011.1 464159 464470 R hypothetical protein complement(464159..464470) Lawsonia intracellularis PHE/MN1-00 4059427 YP_594750.1 CDS pgsA NC_008011.1 464482 465042 R phosphatidylglycerophosphate synthase complement(464482..465042) Lawsonia intracellularis PHE/MN1-00 4059996 YP_594751.1 CDS LI0374 NC_008011.1 465190 466008 R chromosome partitioning ATPase complement(465190..466008) Lawsonia intracellularis PHE/MN1-00 4059428 YP_594752.1 CDS pcm NC_008011.1 466089 466769 R protein-L-isoaspartate carboxylmethyltransferase complement(466089..466769) Lawsonia intracellularis PHE/MN1-00 4060024 YP_594753.1 CDS LI0376 NC_008011.1 467194 468507 D membrane proteins related to metalloendopeptidases 467194..468507 Lawsonia intracellularis PHE/MN1-00 4059429 YP_594754.1 CDS rpsB NC_008011.1 468756 469631 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 468756..469631 Lawsonia intracellularis PHE/MN1-00 4059846 YP_594755.1 CDS tsf NC_008011.1 469657 470541 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 469657..470541 Lawsonia intracellularis PHE/MN1-00 4059504 YP_594756.1 CDS galE NC_008011.1 470643 471623 D nucleoside-diphosphate-sugar epimerases 470643..471623 Lawsonia intracellularis PHE/MN1-00 4060315 YP_594757.1 CDS LI0380 NC_008011.1 471627 472781 D cell wall biogenesis regulatory protein 471627..472781 Lawsonia intracellularis PHE/MN1-00 4059430 YP_594758.1 CDS lgtF NC_008011.1 472788 473591 D cell wall biosynthesis glycosyltransferase 472788..473591 Lawsonia intracellularis PHE/MN1-00 4059647 YP_594759.1 CDS pyrH NC_008011.1 473612 474328 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 473612..474328 Lawsonia intracellularis PHE/MN1-00 4059971 YP_594760.1 CDS frr NC_008011.1 474332 474898 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 474332..474898 Lawsonia intracellularis PHE/MN1-00 4059625 YP_594761.1 CDS yaeS NC_008011.1 474934 475656 D UDP pyrophosphate synthase 474934..475656 Lawsonia intracellularis PHE/MN1-00 4059616 YP_594762.1 CDS cdsA NC_008011.1 475653 476450 D CDP-diglyceride synthetase 475653..476450 Lawsonia intracellularis PHE/MN1-00 4060413 YP_594763.1 CDS dxr NC_008011.1 476513 477721 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 476513..477721 Lawsonia intracellularis PHE/MN1-00 4059299 YP_594764.1 CDS LI0387 NC_008011.1 477721 478845 D membrane-associated Zn-dependent proteases 1 477721..478845 Lawsonia intracellularis PHE/MN1-00 4059431 YP_594765.1 CDS LI0388 NC_008011.1 478842 479636 D hypothetical protein 478842..479636 Lawsonia intracellularis PHE/MN1-00 4059432 YP_594766.1 CDS LI0389 NC_008011.1 480542 481426 D modification methylase BepI (cytosine-specific methyltransferase BepI) 480542..481426 Lawsonia intracellularis PHE/MN1-00 4059433 YP_594767.1 CDS proS NC_008011.1 481800 483527 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(481800..483527) Lawsonia intracellularis PHE/MN1-00 4059982 YP_594768.1 CDS LI0391 NC_008011.1 483648 484544 R Fe-S oxidoreductase complement(483648..484544) Lawsonia intracellularis PHE/MN1-00 4059434 YP_594769.1 CDS mreB NC_008011.1 484633 485673 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 484633..485673 Lawsonia intracellularis PHE/MN1-00 4060129 YP_594770.1 CDS mreC NC_008011.1 485787 486668 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 485787..486668 Lawsonia intracellularis PHE/MN1-00 4060072 YP_594771.1 CDS LI0394 NC_008011.1 486665 487135 D hypothetical protein 486665..487135 Lawsonia intracellularis PHE/MN1-00 4060151 YP_594772.1 CDS LI0395 NC_008011.1 487119 488912 D cell division protein FtsI/penicillin-binding protein 2 487119..488912 Lawsonia intracellularis PHE/MN1-00 4060152 YP_594773.1 CDS rodA NC_008011.1 488937 490052 D rod shape-determining protein RodA 488937..490052 Lawsonia intracellularis PHE/MN1-00 4059911 YP_594774.1 CDS LI0397 NC_008011.1 490077 490424 D cell shape determination protein CcmA 490077..490424 Lawsonia intracellularis PHE/MN1-00 4060153 YP_594775.1 CDS LI0398 NC_008011.1 490519 490941 D F0F1-type ATP synthase, subunit b 490519..490941 Lawsonia intracellularis PHE/MN1-00 4060154 YP_594776.1 CDS atpF NC_008011.1 <490959 491537 D F0F1-type ATP synthase, subunit b <490959..491537 Lawsonia intracellularis PHE/MN1-00 4060391 YP_594777.1 CDS atpE NC_008011.1 491534 492100 D produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 491534..492100 Lawsonia intracellularis PHE/MN1-00 4060390 YP_594778.1 CDS atpD NC_008011.1 492090 493610 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 492090..493610 Lawsonia intracellularis PHE/MN1-00 4060389 YP_594779.1 CDS atpC NC_008011.1 493615 494484 D produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 493615..494484 Lawsonia intracellularis PHE/MN1-00 4059394 YP_594780.1 CDS atpB NC_008011.1 494508 495923 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 494508..495923 Lawsonia intracellularis PHE/MN1-00 4059393 YP_594781.1 CDS atpC NC_008011.1 495934 496335 D produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 495934..496335 Lawsonia intracellularis PHE/MN1-00 4059391 YP_594782.1 CDS xseA NC_008011.1 496471 497913 D exonuclease VII, large subunit 496471..497913 Lawsonia intracellularis PHE/MN1-00 4059614 YP_594783.1 CDS LI0406 NC_008011.1 497938 498807 D membrane proteins related to metalloendopeptidases 497938..498807 Lawsonia intracellularis PHE/MN1-00 4060155 YP_594784.1 CDS LI0407 NC_008011.1 499089 499991 D geranylgeranyl pyrophosphate synthase 499089..499991 Lawsonia intracellularis PHE/MN1-00 4060156 YP_594785.1 CDS dsx NC_008011.1 500065 501978 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 500065..501978 Lawsonia intracellularis PHE/MN1-00 4060386 YP_594786.1 CDS LI0409 NC_008011.1 502001 503026 R ATPase complement(502001..503026) Lawsonia intracellularis PHE/MN1-00 4060157 YP_594787.1 CDS trpA NC_008011.1 504438 505217 R bifunctional tryptophan synthase TRPB complement(504438..505217) Lawsonia intracellularis PHE/MN1-00 4059494 YP_594788.1 CDS trpB NC_008011.1 505228 506397 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(505228..506397) Lawsonia intracellularis PHE/MN1-00 4059495 YP_594789.1 CDS trpF NC_008011.1 506387 507004 R phosphoribosyl anthranilate isomerase complement(506387..507004) Lawsonia intracellularis PHE/MN1-00 4059498 YP_594790.1 CDS trpC_2 NC_008011.1 506982 507704 R indole-3-glycerol phosphate synthase complement(506982..507704) Lawsonia intracellularis PHE/MN1-00 4059496 YP_594791.1 CDS trpD NC_008011.1 507758 508744 R anthranilate phosphoribosyltransferase complement(507758..508744) Lawsonia intracellularis PHE/MN1-00 4059497 YP_594792.1 CDS LI0415 NC_008011.1 508741 509877 R kynureninase (kyurenine hydrolase) complement(508741..509877) Lawsonia intracellularis PHE/MN1-00 4060158 YP_594793.1 CDS LI0416 NC_008011.1 509880 510698 R ABC transporter permease complement(509880..510698) Lawsonia intracellularis PHE/MN1-00 4060159 YP_594794.1 CDS LI0417 NC_008011.1 510688 511422 R ABC transporter ATP-binding protein complement(510688..511422) Lawsonia intracellularis PHE/MN1-00 4060160 YP_594795.1 CDS LI0418 NC_008011.1 511426 512397 R hypothetical protein complement(511426..512397) Lawsonia intracellularis PHE/MN1-00 4060161 YP_594796.1 CDS LI0419 NC_008011.1 <514084 >514919 D short chain dehydrogenase <514084..>514919 Lawsonia intracellularis PHE/MN1-00 4060162 YP_594797.1 CDS bioB NC_008011.1 514967 515935 R biotin synthase complement(514967..515935) Lawsonia intracellularis PHE/MN1-00 4060396 YP_594798.1 CDS bioF NC_008011.1 515952 517097 D 7-keto-8-aminopelargonate synthetase and related enzymes 515952..517097 Lawsonia intracellularis PHE/MN1-00 4060399 YP_594799.1 CDS LI0422 NC_008011.1 517094 517732 D hypothetical protein 517094..517732 Lawsonia intracellularis PHE/MN1-00 4060163 YP_594800.1 CDS bioC NC_008011.1 517752 518495 D ubiE/COQ5 methyltransferase family protein 517752..518495 Lawsonia intracellularis PHE/MN1-00 4060397 YP_594801.1 CDS bioD NC_008011.1 518495 519106 D dethiobiotin synthetase 518495..519106 Lawsonia intracellularis PHE/MN1-00 4060398 YP_594802.1 CDS bioA NC_008011.1 519110 520387 D adenosylmethionine-8-amino-7-oxononanoate aminotransferase 519110..520387 Lawsonia intracellularis PHE/MN1-00 4060395 YP_594803.1 CDS LI0427 NC_008011.1 520457 521032 R hypothetical protein complement(520457..521032) Lawsonia intracellularis PHE/MN1-00 4060164 YP_594804.1 CDS putP NC_008011.1 522545 523912 D sodium-dependent transporter 522545..523912 Lawsonia intracellularis PHE/MN1-00 4059962 YP_594805.1 CDS hemN NC_008011.1 524004 525074 R coproporphyrinogen III oxidase-like protein complement(524004..525074) Lawsonia intracellularis PHE/MN1-00 4060264 YP_594806.1 CDS LI0430 NC_008011.1 525142 525582 D histidine triad nucleotide-binding protein 525142..525582 Lawsonia intracellularis PHE/MN1-00 4060165 YP_594807.1 CDS himA NC_008011.1 525657 525947 D nucleoid DNA-binding protein 525657..525947 Lawsonia intracellularis PHE/MN1-00 4060268 YP_594808.1 CDS LI0432 NC_008011.1 526092 526742 R S-adenosylmethionine-dependent methyltransferase involved in cell division complement(526092..526742) Lawsonia intracellularis PHE/MN1-00 4060166 YP_594809.1 CDS dsbD NC_008011.1 527009 528847 R hypothetical protein complement(527009..528847) Lawsonia intracellularis PHE/MN1-00 4060384 YP_594810.1 CDS LI0434 NC_008011.1 529148 530338 R glycosyltransferase complement(529148..530338) Lawsonia intracellularis PHE/MN1-00 4060167 YP_594811.1 CDS aspC NC_008011.1 530484 531716 D catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis; L,L-diaminopimelate aminotransferase 530484..531716 Lawsonia intracellularis PHE/MN1-00 4059387 YP_594812.1 CDS LI0436 NC_008011.1 531796 532644 R PhyA2 complement(531796..532644) Lawsonia intracellularis PHE/MN1-00 4060168 YP_594813.1 CDS LI0437 NC_008011.1 532566 533117 R histidine acid phosphatase complement(532566..533117) Lawsonia intracellularis PHE/MN1-00 4060169 YP_594814.1 CDS LI0438 NC_008011.1 533368 534693 R PhyA2 complement(533368..534693) Lawsonia intracellularis PHE/MN1-00 4060190 YP_594815.1 CDS hyaA NC_008011.1 535099 536355 D hydrogenase-1 small subunit 535099..536355 Lawsonia intracellularis PHE/MN1-00 4059694 YP_594816.1 CDS hyaB NC_008011.1 536370 538178 D hydrogenase-1 large subunit 536370..538178 Lawsonia intracellularis PHE/MN1-00 4059695 YP_594817.1 CDS hyaC NC_008011.1 538288 538992 D Ni/Fe-hydrogenase 1 B-type cytochrome subunit 538288..538992 Lawsonia intracellularis PHE/MN1-00 4059696 YP_594818.1 CDS hyaD NC_008011.1 538995 539531 D processing of HyaA and HyaB proteins 538995..539531 Lawsonia intracellularis PHE/MN1-00 4059697 YP_594819.1 CDS LI0443 NC_008011.1 540291 540695 D hypothetical protein 540291..540695 Lawsonia intracellularis PHE/MN1-00 4060191 YP_594820.1 CDS LI0444 NC_008011.1 540700 541770 D glycosyltransferase 540700..541770 Lawsonia intracellularis PHE/MN1-00 4060192 YP_594821.1 CDS dtd NC_008011.1 541891 542361 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(541891..542361) Lawsonia intracellularis PHE/MN1-00 4060387 YP_594822.1 CDS LI0446 NC_008011.1 542402 543601 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase complement(542402..543601) Lawsonia intracellularis PHE/MN1-00 4060193 YP_594823.1 CDS LI0447 NC_008011.1 543696 543989 D hypothetical protein 543696..543989 Lawsonia intracellularis PHE/MN1-00 4060194 YP_594824.1 CDS LI0448 NC_008011.1 544048 544812 R hypothetical protein complement(544048..544812) Lawsonia intracellularis PHE/MN1-00 4060195 YP_594825.1 CDS LI0449 NC_008011.1 544847 545644 R hypothetical protein complement(544847..545644) Lawsonia intracellularis PHE/MN1-00 4060196 YP_594826.1 CDS purL NC_008011.1 545767 546591 R phosphoribosylformylglycinamidine synthase domain-containing protein complement(545767..546591) Lawsonia intracellularis PHE/MN1-00 4059958 YP_594827.1 CDS pyrG NC_008011.1 546832 548484 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 546832..548484 Lawsonia intracellularis PHE/MN1-00 4059970 YP_594828.1 CDS kdsA NC_008011.1 548515 549321 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 548515..549321 Lawsonia intracellularis PHE/MN1-00 4059674 YP_594829.1 CDS LI0453 NC_008011.1 549318 549929 D HAD superfamily low specificity phosphatase 549318..549929 Lawsonia intracellularis PHE/MN1-00 4060197 YP_594830.1 CDS LI0454 NC_008011.1 550004 550549 D hypothetical protein 550004..550549 Lawsonia intracellularis PHE/MN1-00 4060198 YP_594831.1 CDS LI0455 NC_008011.1 550649 551218 D hypothetical protein 550649..551218 Lawsonia intracellularis PHE/MN1-00 4060199 YP_594832.1 CDS LI0456 NC_008011.1 551218 551940 D ABC transporter ATPase 551218..551940 Lawsonia intracellularis PHE/MN1-00 4060200 YP_594833.1 CDS rpoN NC_008011.1 552086 553507 D DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein 552086..553507 Lawsonia intracellularis PHE/MN1-00 4059845 YP_594834.1 CDS LI0458 NC_008011.1 553542 554078 D ribosome-associated protein Y (PSrp-1) 553542..554078 Lawsonia intracellularis PHE/MN1-00 4060201 YP_594835.1 CDS LI0459 NC_008011.1 554113 555078 D hypothetical protein 554113..555078 Lawsonia intracellularis PHE/MN1-00 4060202 YP_594836.1 CDS LI0460 NC_008011.1 555553 556104 D outer membrane protein 555553..556104 Lawsonia intracellularis PHE/MN1-00 4060203 YP_594837.1 CDS LI0461 NC_008011.1 556323 557819 R hypothetical protein complement(556323..557819) Lawsonia intracellularis PHE/MN1-00 4060204 YP_594838.1 CDS gltX NC_008011.1 557976 559373 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(557976..559373) Lawsonia intracellularis PHE/MN1-00 4060224 YP_594839.1 CDS LI0463 NC_008011.1 559477 560727 R hypothetical protein complement(559477..560727) Lawsonia intracellularis PHE/MN1-00 4060205 YP_594840.1 CDS pgk NC_008011.1 560781 562121 R phosphoglycerate kinase complement(560781..562121) Lawsonia intracellularis PHE/MN1-00 4059994 YP_594841.1 CDS LI0465 NC_008011.1 562525 563409 D hypothetical protein 562525..563409 Lawsonia intracellularis PHE/MN1-00 4060206 YP_594842.1 CDS galE NC_008011.1 563439 564431 R nucleoside-diphosphate-sugar epimerases complement(563439..564431) Lawsonia intracellularis PHE/MN1-00 4060316 YP_594843.1 CDS cynT NC_008011.1 564532 565308 R carbonic anhydrase complement(564532..565308) Lawsonia intracellularis PHE/MN1-00 4060438 YP_594844.1 CDS rfbB NC_008011.1 566233 567591 D dTDP-D-glucose 4,6-dehydratase 566233..567591 Lawsonia intracellularis PHE/MN1-00 4059951 YP_594845.1 CDS LI0469 NC_008011.1 567584 569458 D hypothetical protein 567584..569458 Lawsonia intracellularis PHE/MN1-00 4060207 YP_594846.1 CDS LI0470 NC_008011.1 569852 570466 D membrane proteins related to metalloendopeptidases 569852..570466 Lawsonia intracellularis PHE/MN1-00 4060208 YP_594847.1 CDS LI0471 NC_008011.1 570504 571607 D xylanase/chitin deacetylase 570504..571607 Lawsonia intracellularis PHE/MN1-00 4060209 YP_594848.1 CDS LI0472 NC_008011.1 571638 572678 R permease complement(571638..572678) Lawsonia intracellularis PHE/MN1-00 4059512 YP_594849.1 CDS LI0473 NC_008011.1 573983 577249 R DNA methylase complement(573983..577249) Lawsonia intracellularis PHE/MN1-00 4059513 YP_594850.1 CDS LI0474 NC_008011.1 579345 579749 R tellurite resistance complement(579345..579749) Lawsonia intracellularis PHE/MN1-00 4059514 YP_594851.1 CDS LI0475 NC_008011.1 <579945 580343 R hypothetical protein complement(<579945..580343) Lawsonia intracellularis PHE/MN1-00 4059515 YP_594852.1 CDS nrdA NC_008011.1 581215 583965 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 581215..583965 Lawsonia intracellularis PHE/MN1-00 4060062 YP_594853.1 CDS nrdB NC_008011.1 584106 585107 D ribonucleotide reductase, beta subunit 584106..585107 Lawsonia intracellularis PHE/MN1-00 4060063 YP_594854.1 CDS LI0478 NC_008011.1 585484 586632 R cytosine deaminase-like protein complement(585484..586632) Lawsonia intracellularis PHE/MN1-00 4059516 YP_594855.1 CDS LI0479 NC_008011.1 587222 588658 D alginate O-acetylation protein 587222..588658 Lawsonia intracellularis PHE/MN1-00 4059517 YP_594856.1 CDS LI0480 NC_008011.1 588676 590637 D esterase MesA 588676..590637 Lawsonia intracellularis PHE/MN1-00 4059518 YP_594857.1 CDS LI0481 NC_008011.1 590701 591078 D hypothetical protein 590701..591078 Lawsonia intracellularis PHE/MN1-00 4059519 YP_594858.1 CDS motA NC_008011.1 591277 592125 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 591277..592125 Lawsonia intracellularis PHE/MN1-00 4060123 YP_594859.1 CDS motB NC_008011.1 592170 592883 D flagellar motor protein 592170..592883 Lawsonia intracellularis PHE/MN1-00 4060125 YP_594860.1 CDS LI0484 NC_008011.1 592910 594616 R hypothetical protein complement(592910..594616) Lawsonia intracellularis PHE/MN1-00 4059520 YP_594861.1 CDS LI0485 NC_008011.1 594907 596061 R major facilitator superfamily permease complement(594907..596061) Lawsonia intracellularis PHE/MN1-00 4059521 YP_594862.1 CDS motA NC_008011.1 596408 597160 D flagellar motor component 596408..597160 Lawsonia intracellularis PHE/MN1-00 4060124 YP_594863.1 CDS motB NC_008011.1 597267 597887 D flagellar motor protein 597267..597887 Lawsonia intracellularis PHE/MN1-00 4060126 YP_594864.1 CDS accC NC_008011.1 598269 599687 D biotin carboxylase 598269..599687 Lawsonia intracellularis PHE/MN1-00 4060338 YP_594865.1 CDS LI0489 NC_008011.1 599700 601946 D Acetyl-CoA carboxylase alpha subunit 599700..601946 Lawsonia intracellularis PHE/MN1-00 4059522 YP_594866.1 CDS LI0490 NC_008011.1 601994 602644 D hypothetical protein 601994..602644 Lawsonia intracellularis PHE/MN1-00 4059523 YP_594867.1 CDS LI0491 NC_008011.1 602649 602993 D hypothetical protein 602649..602993 Lawsonia intracellularis PHE/MN1-00 4059524 YP_594868.1 CDS LI0492 NC_008011.1 603031 603486 D single-stranded DNA-binding protein 603031..603486 Lawsonia intracellularis PHE/MN1-00 4059525 YP_594869.1 CDS glnS NC_008011.1 603604 605301 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(603604..605301) Lawsonia intracellularis PHE/MN1-00 4060217 YP_594870.1 CDS LI0494 NC_008011.1 605340 605717 R hypothetical protein complement(605340..605717) Lawsonia intracellularis PHE/MN1-00 4059526 YP_594871.1 CDS LI0495 NC_008011.1 605999 607135 D glycosyltransferase 605999..607135 Lawsonia intracellularis PHE/MN1-00 4059527 YP_594872.1 CDS LI0496 NC_008011.1 607449 608588 D branched chain amino acid ABC transporter, periplasmic amino acid-binding protein 607449..608588 Lawsonia intracellularis PHE/MN1-00 4059528 YP_594873.1 CDS livH NC_008011.1 608669 609562 D branched chain amino acid ABC transporter, permease 608669..609562 Lawsonia intracellularis PHE/MN1-00 4059655 YP_594874.1 CDS livM NC_008011.1 609559 610602 D branched chain amino acid ABC transporter, permease 609559..610602 Lawsonia intracellularis PHE/MN1-00 4059657 YP_594875.1 CDS livG NC_008011.1 610599 611405 D branched chain amino acid ABC transporter, ATP-binding protein 610599..611405 Lawsonia intracellularis PHE/MN1-00 4059653 YP_594876.1 CDS livF NC_008011.1 611398 612120 D branched chain amino acid ABC transporter, ATP-binding protein 611398..612120 Lawsonia intracellularis PHE/MN1-00 4059651 YP_594877.1 CDS hppA NC_008011.1 612389 614464 D pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 612389..614464 Lawsonia intracellularis PHE/MN1-00 4060011 YP_594878.1 CDS pabC NC_008011.1 614756 615940 R periplasmic solute-binding protein complement(614756..615940) Lawsonia intracellularis PHE/MN1-00 4060020 YP_594879.1 CDS LI0503 NC_008011.1 615937 616365 R endonuclease complement(615937..616365) Lawsonia intracellularis PHE/MN1-00 4059529 YP_594880.1 CDS thiG NC_008011.1 617036 617818 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 617036..617818 Lawsonia intracellularis PHE/MN1-00 4059820 YP_594881.1 CDS thiH NC_008011.1 617868 618959 D thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes 617868..618959 Lawsonia intracellularis PHE/MN1-00 4059821 YP_594882.1 CDS thiF NC_008011.1 618969 619589 D catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate; thiamine biosynthesis protein ThiF 618969..619589 Lawsonia intracellularis PHE/MN1-00 4059819 YP_594883.1 CDS LI0507 NC_008011.1 619631 620785 R hypothetical protein complement(619631..620785) Lawsonia intracellularis PHE/MN1-00 4059530 YP_594884.1 CDS LI0508 NC_008011.1 620873 622246 R multidrug resistance protein norM complement(620873..622246) Lawsonia intracellularis PHE/MN1-00 4060092 YP_594885.1 CDS LI0509 NC_008011.1 622366 623799 R carbon starvation protein, membrane protein complement(622366..623799) Lawsonia intracellularis PHE/MN1-00 4060093 YP_594886.1 CDS terC NC_008011.1 624527 625507 D tellurium resistance protein TerC 624527..625507 Lawsonia intracellularis PHE/MN1-00 4059812 YP_594887.1 CDS LI0511 NC_008011.1 625603 626085 R hypothetical protein complement(625603..626085) Lawsonia intracellularis PHE/MN1-00 4060094 YP_594888.1 CDS LI0512 NC_008011.1 626142 627587 R lipopolysaccharide synthesis sugar transferase complement(626142..627587) Lawsonia intracellularis PHE/MN1-00 4060095 YP_594889.1 CDS LI0513 NC_008011.1 627646 628749 R glycosyltransferase complement(627646..628749) Lawsonia intracellularis PHE/MN1-00 4060096 YP_594890.1 CDS LI0514 NC_008011.1 628999 630420 D Na+/H+ antiporter NhaD and related arsenite permeases 628999..630420 Lawsonia intracellularis PHE/MN1-00 4060097 YP_594891.1 CDS ispB NC_008011.1 630795 631769 D geranylgeranyl pyrophosphate synthase 630795..631769 Lawsonia intracellularis PHE/MN1-00 4059671 YP_594892.1 CDS purL NC_008011.1 631796 634774 D phosphoribosylformylglycinamidine synthase domain-containing protein 631796..634774 Lawsonia intracellularis PHE/MN1-00 4059959 YP_594893.1 CDS rpoD NC_008011.1 634857 636629 R DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) complement(634857..636629) Lawsonia intracellularis PHE/MN1-00 4059844 YP_594894.1 CDS dnaG NC_008011.1 636619 638349 R DNA primase complement(636619..638349) Lawsonia intracellularis PHE/MN1-00 4060377 YP_594895.1 CDS LI0519 NC_008011.1 638759 639226 R hypothetical protein complement(638759..639226) Lawsonia intracellularis PHE/MN1-00 4060098 YP_594896.1 CDS LI0520 NC_008011.1 639808 640170 D hypothetical protein 639808..640170 Lawsonia intracellularis PHE/MN1-00 4060099 YP_594897.1 CDS ksgA NC_008011.1 640294 641109 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(640294..641109) Lawsonia intracellularis PHE/MN1-00 4059679 YP_594898.1 CDS LI0522 NC_008011.1 641246 642406 D glycosyltransferase 641246..642406 Lawsonia intracellularis PHE/MN1-00 4060100 YP_594899.1 CDS LI0523 NC_008011.1 642466 642885 R hypothetical protein complement(642466..642885) Lawsonia intracellularis PHE/MN1-00 4060101 YP_594900.1 CDS LI0524 NC_008011.1 642894 643238 R hypothetical protein complement(642894..643238) Lawsonia intracellularis PHE/MN1-00 4060102 YP_594901.1 CDS LI0525 NC_008011.1 643246 643974 R flagellar basal body-associated protein complement(643246..643974) Lawsonia intracellularis PHE/MN1-00 4060103 YP_594902.1 CDS cheY NC_008011.1 644060 644440 R CheY-like receiver complement(644060..644440) Lawsonia intracellularis PHE/MN1-00 4060422 YP_594903.1 CDS fleN NC_008011.1 645210 646025 R chromosome partitioning ATPase complement(645210..646025) Lawsonia intracellularis PHE/MN1-00 4059314 YP_594904.1 CDS flhF NC_008011.1 646068 647129 R flagellar GTP-binding protein complement(646068..647129) Lawsonia intracellularis PHE/MN1-00 4059733 YP_594905.1 CDS flhA NC_008011.1 647129 649219 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(647129..649219) Lawsonia intracellularis PHE/MN1-00 4060104 YP_594906.1 CDS flhB NC_008011.1 649308 650381 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(649308..650381) Lawsonia intracellularis PHE/MN1-00 4059732 YP_594907.1 CDS fliR NC_008011.1 650434 651222 R flagellar biosynthesis pathway, component FliR complement(650434..651222) Lawsonia intracellularis PHE/MN1-00 4059746 YP_594908.1 CDS LI0533 NC_008011.1 651739 652329 D transcription elongation factor 651739..652329 Lawsonia intracellularis PHE/MN1-00 4060105 YP_594909.1 CDS nusA NC_008011.1 652326 653648 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 652326..653648 Lawsonia intracellularis PHE/MN1-00 4060068 YP_594910.1 CDS infB NC_008011.1 653879 656764 D translation initiation factor 2 (IF-2; GTPase) 653879..656764 Lawsonia intracellularis PHE/MN1-00 4059669 YP_594911.1 CDS mgpa NC_008011.1 657048 658046 D exopolyphosphatase-like protein 657048..658046 Lawsonia intracellularis PHE/MN1-00 4060116 YP_594912.1 CDS SctR NC_008011.1 658119 658769 R part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein complement(658119..658769) Lawsonia intracellularis PHE/MN1-00 4059634 YP_594913.1 CDS LI0538 NC_008011.1 658794 659876 R translocation protein in type III secretion complement(658794..659876) Lawsonia intracellularis PHE/MN1-00 4060106 YP_594914.1 CDS LI0539 NC_008011.1 659919 660416 R hypothetical protein complement(659919..660416) Lawsonia intracellularis PHE/MN1-00 4060107 YP_594915.1 CDS sctN NC_008011.1 660438 661754 R type III secretion system ATPase complement(660438..661754) Lawsonia intracellularis PHE/MN1-00 4059633 YP_594916.1 CDS sctL NC_008011.1 661775 662389 R type III secretion system protein complement(661775..662389) Lawsonia intracellularis PHE/MN1-00 4059632 YP_594917.1 CDS LI0542 NC_008011.1 662368 663072 R hypothetical protein complement(662368..663072) Lawsonia intracellularis PHE/MN1-00 4060108 YP_594918.1 CDS nolT NC_008011.1 663072 663944 R LscJ complement(663072..663944) Lawsonia intracellularis PHE/MN1-00 4060061 YP_594919.1 CDS LI0544 NC_008011.1 663958 664335 R hypothetical protein complement(663958..664335) Lawsonia intracellularis PHE/MN1-00 4060109 YP_594920.1 CDS LI0545 NC_008011.1 665261 665557 R hypothetical protein complement(665261..665557) Lawsonia intracellularis PHE/MN1-00 4060110 YP_594921.1 CDS LI0546 NC_008011.1 665820 666182 D hypothetical protein 665820..666182 Lawsonia intracellularis PHE/MN1-00 4060111 YP_594922.1 CDS LI0547 NC_008011.1 666388 666729 D hypothetical protein 666388..666729 Lawsonia intracellularis PHE/MN1-00 4059565 YP_594923.1 CDS yscV NC_008011.1 666726 668828 D type III secretion pore protein 666726..668828 Lawsonia intracellularis PHE/MN1-00 4059543 YP_594924.1 CDS yscS NC_008011.1 668846 669106 D translocation protein in type III secretion 668846..669106 Lawsonia intracellularis PHE/MN1-00 4059540 YP_594925.1 CDS yscT NC_008011.1 669154 669969 D Type III secretion component protein SctT 669154..669969 Lawsonia intracellularis PHE/MN1-00 4059541 YP_594926.1 CDS yscU NC_008011.1 669966 671048 D translocation protein in type III secretion 669966..671048 Lawsonia intracellularis PHE/MN1-00 4059542 YP_594927.1 CDS LI0552 NC_008011.1 677116 681264 D Signal transduction histidine kinase 677116..681264 Lawsonia intracellularis PHE/MN1-00 4059566 YP_594928.1 CDS lysA NC_008011.1 681626 682891 D diaminopimelate decarboxylase 681626..682891 Lawsonia intracellularis PHE/MN1-00 4060138 YP_594929.1 CDS LI0554 NC_008011.1 682917 684095 D hypothetical protein 682917..684095 Lawsonia intracellularis PHE/MN1-00 4059567 YP_594930.1 CDS LI0555 NC_008011.1 684290 685045 D hypothetical protein 684290..685045 Lawsonia intracellularis PHE/MN1-00 4059568 YP_594931.1 CDS LI0556 NC_008011.1 685227 686414 D major facilitator superfamily permease 685227..686414 Lawsonia intracellularis PHE/MN1-00 4059569 YP_594932.1 CDS bacA NC_008011.1 686543 687343 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 686543..687343 Lawsonia intracellularis PHE/MN1-00 4060393 YP_594933.1 CDS LI0558 NC_008011.1 687407 688678 R competence protein ComGF complement(687407..688678) Lawsonia intracellularis PHE/MN1-00 4059570 YP_594934.1 CDS rplM NC_008011.1 688844 689278 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 688844..689278 Lawsonia intracellularis PHE/MN1-00 4059885 YP_594935.1 CDS rpsI NC_008011.1 689297 689689 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 689297..689689 Lawsonia intracellularis PHE/MN1-00 4059571 YP_594936.1 CDS LI0561 NC_008011.1 689868 691523 D metallo-beta-lactamase superfamily hydrolase 689868..691523 Lawsonia intracellularis PHE/MN1-00 4059572 YP_594937.1 CDS LI0562 NC_008011.1 691765 692793 D hypothetical protein 691765..692793 Lawsonia intracellularis PHE/MN1-00 4059573 YP_594938.1 CDS LI0563 NC_008011.1 693085 693444 R hypothetical protein complement(693085..693444) Lawsonia intracellularis PHE/MN1-00 4059574 YP_594939.1 CDS pgpA NC_008011.1 693561 694052 D phosphatidylglycerophosphatase A and related proteins 693561..694052 Lawsonia intracellularis PHE/MN1-00 4059995 YP_594940.1 CDS LI0565 NC_008011.1 694166 694642 D hypothetical protein 694166..694642 Lawsonia intracellularis PHE/MN1-00 4059575 YP_594941.1 CDS flgE NC_008011.1 694775 696847 R flagellar hook protein FlgE complement(694775..696847) Lawsonia intracellularis PHE/MN1-00 4059723 YP_594942.1 CDS LI0567 NC_008011.1 696931 697770 R flagellar hook capping protein complement(696931..697770) Lawsonia intracellularis PHE/MN1-00 4059576 YP_594943.1 CDS LI0568 NC_008011.1 697783 699609 R flagellar hook-length control protein complement(697783..699609) Lawsonia intracellularis PHE/MN1-00 4059577 YP_594944.1 CDS LI0569 NC_008011.1 699820 701229 R ADP-heptose:LPS heptosyltransferase complement(699820..701229) Lawsonia intracellularis PHE/MN1-00 4059578 YP_594945.1 CDS fliC NC_008011.1 701958 702842 D flagellin-like protein 701958..702842 Lawsonia intracellularis PHE/MN1-00 4059735 YP_594946.1 CDS rnc NC_008011.1 703046 703747 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(703046..703747) Lawsonia intracellularis PHE/MN1-00 4059906 YP_594947.1 CDS LI0572 NC_008011.1 703881 704216 D hypothetical protein 703881..704216 Lawsonia intracellularis PHE/MN1-00 4059579 YP_594948.1 CDS LI0573 NC_008011.1 704639 705160 R RimM protein, required for 16S rRNA processing complement(704639..705160) Lawsonia intracellularis PHE/MN1-00 4059580 YP_594949.1 CDS LI0574 NC_008011.1 705170 705403 R RNA-binding protein complement(705170..705403) Lawsonia intracellularis PHE/MN1-00 4059581 YP_594950.1 CDS LI0575 NC_008011.1 705860 707374 R Signal renition particle GTPase complement(705860..707374) Lawsonia intracellularis PHE/MN1-00 4059582 YP_594951.1 CDS trmA NC_008011.1 707511 708923 R RNA methyltransferase complement(707511..708923) Lawsonia intracellularis PHE/MN1-00 4059835 YP_594952.1 CDS LI0577 NC_008011.1 708959 709837 R dTDP-glucose pyrophosphorylase complement(708959..709837) Lawsonia intracellularis PHE/MN1-00 4059583 YP_594953.1 CDS purH NC_008011.1 709985 710578 D AICAR transformylase/IMP cyclohydrolase PurH 709985..710578 Lawsonia intracellularis PHE/MN1-00 4059956 YP_594954.1 CDS mutT NC_008011.1 710794 711201 D NTP pyrophosphohydrolases including oxidative damage repair enzymes 710794..711201 Lawsonia intracellularis PHE/MN1-00 4060084 YP_594955.1 CDS LI0580 NC_008011.1 711302 712312 R nucleoside-diphosphate-sugar epimerases complement(711302..712312) Lawsonia intracellularis PHE/MN1-00 4059584 YP_594956.1 CDS LI0581 NC_008011.1 712325 713056 R hypothetical protein complement(712325..713056) Lawsonia intracellularis PHE/MN1-00 4059585 YP_594957.1 CDS LI0582 NC_008011.1 713038 714246 R phosphopantothenoylcysteine synthetase/decarboxylase complement(713038..714246) Lawsonia intracellularis PHE/MN1-00 4059586 YP_594958.1 CDS LI0583 NC_008011.1 714243 714791 R hypothetical protein complement(714243..714791) Lawsonia intracellularis PHE/MN1-00 4059587 YP_594959.1 CDS LI0584 NC_008011.1 715334 715945 D hypothetical protein 715334..715945 Lawsonia intracellularis PHE/MN1-00 4059588 YP_594960.1 CDS LI0585 NC_008011.1 716001 717314 D DNA repair exonuclease 716001..717314 Lawsonia intracellularis PHE/MN1-00 4059589 YP_594961.1 CDS LI0586 NC_008011.1 717314 721276 D hypothetical protein 717314..721276 Lawsonia intracellularis PHE/MN1-00 4059590 YP_594962.1 CDS LI0587 NC_008011.1 721314 721958 R hypothetical protein complement(721314..721958) Lawsonia intracellularis PHE/MN1-00 4059591 YP_594963.1 CDS tatC NC_008011.1 722079 723026 R Sec-independent protein secretion pathway component TatC complement(722079..723026) Lawsonia intracellularis PHE/MN1-00 4059810 YP_594964.1 CDS LI0589 NC_008011.1 723056 723421 R Sec-independent protein secretion pathway components complement(723056..723421) Lawsonia intracellularis PHE/MN1-00 4059592 YP_594965.1 CDS guaA NC_008011.1 723704 725245 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(723704..725245) Lawsonia intracellularis PHE/MN1-00 4060256 YP_594966.1 CDS guaB NC_008011.1 725358 726833 R IMP dehydrogenase/GMP reductase complement(725358..726833) Lawsonia intracellularis PHE/MN1-00 4060257 YP_594967.1 CDS maa NC_008011.1 727151 727738 D maltose transacetylase 727151..727738 Lawsonia intracellularis PHE/MN1-00 4060143 YP_594968.1 CDS cls NC_008011.1 727939 729378 D phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase-like protein 727939..729378 Lawsonia intracellularis PHE/MN1-00 4060429 YP_594969.1 CDS rnb NC_008011.1 729401 731842 R exoribonuclease R complement(729401..731842) Lawsonia intracellularis PHE/MN1-00 4059905 YP_594970.1 CDS lpxK NC_008011.1 731866 733320 R tetraacyldisaccharide-1-P 4'-kinase complement(731866..733320) Lawsonia intracellularis PHE/MN1-00 4060136 YP_594971.1 CDS tpx NC_008011.1 733491 734009 R peroxiredoxin complement(733491..734009) Lawsonia intracellularis PHE/MN1-00 4059832 YP_594972.1 CDS LI0597 NC_008011.1 734850 737261 D TPR repeat-containing protein 734850..737261 Lawsonia intracellularis PHE/MN1-00 4059593 YP_594973.1 CDS zntA NC_008011.1 737302 739368 R cation-transporting ATPase, P-type complement(737302..739368) Lawsonia intracellularis PHE/MN1-00 4059544 YP_594974.1 CDS panF NC_008011.1 739657 741138 R mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter complement(739657..741138) Lawsonia intracellularis PHE/MN1-00 4060022 YP_594975.1 CDS LI0600 NC_008011.1 741141 741506 R hypothetical protein complement(741141..741506) Lawsonia intracellularis PHE/MN1-00 4059594 YP_594976.1 CDS LI0601 NC_008011.1 742192 743511 D voltage-gated chloride channel family protein 742192..743511 Lawsonia intracellularis PHE/MN1-00 4059595 YP_594977.1 CDS LI0602 NC_008011.1 743611 744357 D metal dependent hydrolases 743611..744357 Lawsonia intracellularis PHE/MN1-00 4059596 YP_594978.1 CDS LI0603 NC_008011.1 744711 746285 D two-component response regulator 744711..746285 Lawsonia intracellularis PHE/MN1-00 4059597 YP_594979.1 CDS LI0604 NC_008011.1 746343 747425 D PleD 746343..747425 Lawsonia intracellularis PHE/MN1-00 4059598 YP_594980.1 CDS LI0605 NC_008011.1 747467 748333 R hypothetical protein complement(747467..748333) Lawsonia intracellularis PHE/MN1-00 4059599 YP_594981.1 CDS LI0606 NC_008011.1 748457 749158 R transcriptional regulator complement(748457..749158) Lawsonia intracellularis PHE/MN1-00 4059600 YP_594982.1 CDS LI0607 NC_008011.1 749754 751250 R TPR repeat-containing Zn-dependent protease complement(749754..751250) Lawsonia intracellularis PHE/MN1-00 4059601 YP_594983.1 CDS cysS NC_008011.1 751382 752839 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(751382..752839) Lawsonia intracellularis PHE/MN1-00 4060443 YP_594984.1 CDS rpiB NC_008011.1 752940 753368 R ribose 5-phosphate isomerase RpiB complement(752940..753368) Lawsonia intracellularis PHE/MN1-00 4059913 YP_594985.1 CDS LI0610 NC_008011.1 753377 753721 R hypothetical protein complement(753377..753721) Lawsonia intracellularis PHE/MN1-00 4059602 YP_594986.1 CDS LI0611 NC_008011.1 753798 754583 R hypothetical protein complement(753798..754583) Lawsonia intracellularis PHE/MN1-00 4059603 YP_594987.1 CDS LI0612 NC_008011.1 754591 756312 R TPR repeat-containing protein complement(754591..756312) Lawsonia intracellularis PHE/MN1-00 4059702 YP_594988.1 CDS sigB NC_008011.1 756332 757489 R DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) complement(756332..757489) Lawsonia intracellularis PHE/MN1-00 4059800 YP_594989.1 CDS LI0614 NC_008011.1 758603 759070 D Thiol-disulfide isomerase and thioredoxins 758603..759070 Lawsonia intracellularis PHE/MN1-00 4059703 YP_594990.1 CDS LI0615 NC_008011.1 759733 760479 D hypothetical protein 759733..760479 Lawsonia intracellularis PHE/MN1-00 4059704 YP_594991.1 CDS radA NC_008011.1 760506 761837 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 760506..761837 Lawsonia intracellularis PHE/MN1-00 4059936 YP_594992.1 CDS yljA NC_008011.1 761962 762291 D hypothetical protein 761962..762291 Lawsonia intracellularis PHE/MN1-00 4059535 YP_594993.1 CDS LI0618 NC_008011.1 762288 764534 D ATPases with chaperone activity, ATP-binding subunit 762288..764534 Lawsonia intracellularis PHE/MN1-00 4059705 YP_594994.1 CDS aat NC_008011.1 764629 765315 D leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 764629..765315 Lawsonia intracellularis PHE/MN1-00 4060337 YP_594995.1 CDS clr3 NC_008011.1 765529 766827 R deacetylase complement(765529..766827) Lawsonia intracellularis PHE/MN1-00 4060428 YP_594996.1 CDS LI0621 NC_008011.1 767002 767973 R nucleoside-diphosphate-sugar epimerases complement(767002..767973) Lawsonia intracellularis PHE/MN1-00 4059706 YP_594997.1 CDS obgE NC_008011.1 768129 769223 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(768129..769223) Lawsonia intracellularis PHE/MN1-00 4059707 YP_594998.1 CDS rplU NC_008011.1 769665 769973 R 50S ribosomal protein L21 complement(769665..769973) Lawsonia intracellularis PHE/MN1-00 4059894 YP_594999.1 CDS groES NC_008011.1 770472 770777 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 770472..770777 Lawsonia intracellularis PHE/MN1-00 4059708 YP_595000.1 CDS groEL NC_008011.1 770925 772571 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 770925..772571 Lawsonia intracellularis PHE/MN1-00 4059709 YP_595001.1 CDS LI0626 NC_008011.1 772698 773579 D protoporphyrinogen oxidase 772698..773579 Lawsonia intracellularis PHE/MN1-00 4059710 YP_595002.1 CDS lpxC NC_008011.1 773705 774619 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 773705..774619 Lawsonia intracellularis PHE/MN1-00 4060134 YP_595003.1 CDS mutL NC_008011.1 774694 776640 D DNA mismatch repair ATPase 774694..776640 Lawsonia intracellularis PHE/MN1-00 4060081 YP_595004.1 CDS LI0629 NC_008011.1 776669 778213 R hypothetical protein complement(776669..778213) Lawsonia intracellularis PHE/MN1-00 4059711 YP_595005.1 CDS secA NC_008011.1 778307 780802 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(778307..780802) Lawsonia intracellularis PHE/MN1-00 4059635 YP_595006.1 CDS hypE NC_008011.1 780948 781964 R hydrogenase maturation factor complement(780948..781964) Lawsonia intracellularis PHE/MN1-00 4059664 YP_595007.1 CDS LI0632 NC_008011.1 782118 783515 R major facilitator superfamily permease complement(782118..783515) Lawsonia intracellularis PHE/MN1-00 4059712 YP_595008.1 CDS flgM NC_008011.1 783773 784090 R hypothetical protein complement(783773..784090) Lawsonia intracellularis PHE/MN1-00 4059731 YP_595009.1 CDS LI0634 NC_008011.1 784118 784528 R hypothetical protein complement(784118..784528) Lawsonia intracellularis PHE/MN1-00 4059713 YP_595010.1 CDS paaK NC_008011.1 784911 786176 D coenzyme F390 synthetase 784911..786176 Lawsonia intracellularis PHE/MN1-00 4060019 YP_595011.1 CDS LI0636 NC_008011.1 787082 787888 R hypothetical protein complement(787082..787888) Lawsonia intracellularis PHE/MN1-00 4059714 YP_595012.1 CDS mutM NC_008011.1 787956 788795 R formamidopyrimidine-DNA glycosylase complement(787956..788795) Lawsonia intracellularis PHE/MN1-00 4060082 YP_595013.1 CDS LI0638 NC_008011.1 788870 789181 R hypothetical protein complement(788870..789181) Lawsonia intracellularis PHE/MN1-00 4059715 YP_595014.1 CDS fliP NC_008011.1 789827 790615 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(789827..790615) Lawsonia intracellularis PHE/MN1-00 4059745 YP_595015.1 CDS LI0640 NC_008011.1 790596 791090 R flagellar biogenesis protein complement(790596..791090) Lawsonia intracellularis PHE/MN1-00 4059716 YP_595016.1 CDS fliN NC_008011.1 791116 791610 R flagellar motor switch/type III secretory pathway protein complement(791116..791610) Lawsonia intracellularis PHE/MN1-00 4059744 YP_595017.1 CDS fliL NC_008011.1 791623 792192 R flagellar basal body-associated protein complement(791623..792192) Lawsonia intracellularis PHE/MN1-00 4059742 YP_595018.1 CDS LI0643 NC_008011.1 792334 793035 R TIM-barrel fold family protein complement(792334..793035) Lawsonia intracellularis PHE/MN1-00 4059717 YP_595019.1 CDS era NC_008011.1 793032 794006 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(793032..794006) Lawsonia intracellularis PHE/MN1-00 4059718 YP_595020.1 CDS htpX NC_008011.1 794233 795093 R Zn-dependent protease with chaperone function complement(794233..795093) Lawsonia intracellularis PHE/MN1-00 4059691 YP_595021.1 CDS LI0646 NC_008011.1 795375 797069 D N-methylhydantoinase A/acetone carboxylase, beta subunit 795375..797069 Lawsonia intracellularis PHE/MN1-00 4059719 YP_595022.1 CDS LI0647 NC_008011.1 797066 798295 R hypothetical protein complement(797066..798295) Lawsonia intracellularis PHE/MN1-00 4059720 YP_595023.1 CDS valS NC_008011.1 799057 801705 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 799057..801705 Lawsonia intracellularis PHE/MN1-00 4059610 YP_595024.1 CDS LI0649 NC_008011.1 802639 805194 D hypothetical protein 802639..805194 Lawsonia intracellularis PHE/MN1-00 4059545 YP_595025.1 CDS LI0650 NC_008011.1 806068 808959 D Zn-dependent peptidases, insulinase-like 806068..808959 Lawsonia intracellularis PHE/MN1-00 4059546 YP_595026.1 CDS nadh NC_008011.1 809068 810786 D rhodanese-related sulfurtransferase 809068..810786 Lawsonia intracellularis PHE/MN1-00 4060091 YP_595027.1 CDS LI0652 NC_008011.1 810827 811642 R DNA adenine methylase complement(810827..811642) Lawsonia intracellularis PHE/MN1-00 4059547 YP_595028.1 CDS LI0653 NC_008011.1 811686 812498 R Zn-dependent protease with chaperone function complement(811686..812498) Lawsonia intracellularis PHE/MN1-00 4059548 YP_595029.1 CDS topA NC_008011.1 812614 814878 D zinc finger domain-containing protein 812614..814878 Lawsonia intracellularis PHE/MN1-00 4059830 YP_595030.1 CDS gloB NC_008011.1 814978 815604 D Zn-dependent hydrolases, including glyoxylases 814978..815604 Lawsonia intracellularis PHE/MN1-00 4060218 YP_595031.1 CDS argG NC_008011.1 815668 816861 D catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 815668..816861 Lawsonia intracellularis PHE/MN1-00 4059380 YP_595032.1 CDS argH NC_008011.1 816949 818331 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 816949..818331 Lawsonia intracellularis PHE/MN1-00 4059381 YP_595033.1 CDS trmU NC_008011.1 818505 819497 D tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase 818505..819497 Lawsonia intracellularis PHE/MN1-00 4059493 YP_595034.1 CDS LI0659 NC_008011.1 819913 820452 D shikimate kinase 819913..820452 Lawsonia intracellularis PHE/MN1-00 4059549 YP_595035.1 CDS bfr NC_008011.1 820449 820991 R bacterioferritin (cytochrome b1) complement(820449..820991) Lawsonia intracellularis PHE/MN1-00 4060394 YP_595036.1 CDS glmS NC_008011.1 821433 823262 D glucosamine 6-phosphate synthetase 821433..823262 Lawsonia intracellularis PHE/MN1-00 4060327 YP_595037.1 CDS LI0662 NC_008011.1 823446 826448 D hypothetical protein 823446..826448 Lawsonia intracellularis PHE/MN1-00 4059550 YP_595038.1 CDS LI0663 NC_008011.1 828562 828969 D hypothetical protein 828562..828969 Lawsonia intracellularis PHE/MN1-00 4059551 YP_595039.1 CDS LI0664 NC_008011.1 829283 830440 D hypothetical protein 829283..830440 Lawsonia intracellularis PHE/MN1-00 4059552 YP_595040.1 CDS LI0665 NC_008011.1 830885 831484 R hypothetical protein complement(830885..831484) Lawsonia intracellularis PHE/MN1-00 4059553 YP_595041.1 CDS LI0666 NC_008011.1 831665 832279 R hypothetical protein complement(831665..832279) Lawsonia intracellularis PHE/MN1-00 4059554 YP_595042.1 CDS LI0667 NC_008011.1 833929 835044 R hypothetical protein complement(833929..835044) Lawsonia intracellularis PHE/MN1-00 4059555 YP_595043.1 CDS LI0668 NC_008011.1 835309 836481 R hypothetical protein complement(835309..836481) Lawsonia intracellularis PHE/MN1-00 4059556 YP_595044.1 CDS LI0669 NC_008011.1 <836694 837119 R hypothetical protein complement(<836694..837119) Lawsonia intracellularis PHE/MN1-00 4059557 YP_595045.1 CDS ahcY NC_008011.1 839619 841052 D catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 839619..841052 Lawsonia intracellularis PHE/MN1-00 4060343 YP_595046.1 CDS serA NC_008011.1 841336 842244 D phosphoglycerate dehydrogenase and related dehydrogenases 841336..842244 Lawsonia intracellularis PHE/MN1-00 4059642 YP_595047.1 CDS pcrA NC_008011.1 842275 844410 D superfamily I DNA/RNA helicase 842275..844410 Lawsonia intracellularis PHE/MN1-00 4060025 YP_595048.1 CDS thiL NC_008011.1 844426 845448 D thiamine monophosphate kinase 844426..845448 Lawsonia intracellularis PHE/MN1-00 4059822 YP_595049.1 CDS LI0674 NC_008011.1 845474 846838 R hypothetical protein complement(845474..846838) Lawsonia intracellularis PHE/MN1-00 4059558 YP_595050.1 CDS hflK NC_008011.1 847108 848259 D membrane protease subunits, stomatin/prohibitin homologs 847108..848259 Lawsonia intracellularis PHE/MN1-00 4060267 YP_595051.1 CDS hflC NC_008011.1 848260 849111 D membrane protease subunits, stomatin/prohibitin homologs 848260..849111 Lawsonia intracellularis PHE/MN1-00 4060266 YP_595052.1 CDS LI0677 NC_008011.1 849077 849838 D hypothetical protein 849077..849838 Lawsonia intracellularis PHE/MN1-00 4059559 YP_595053.1 CDS LI0678 NC_008011.1 849897 851219 R 2-methylthioadenine synthetase complement(849897..851219) Lawsonia intracellularis PHE/MN1-00 4059560 YP_595054.1 CDS LI0679 NC_008011.1 851253 852002 D xanthosine triphosphate pyrophosphatase 851253..852002 Lawsonia intracellularis PHE/MN1-00 4059561 YP_595055.1 CDS LI0680 NC_008011.1 852068 853144 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 852068..853144 Lawsonia intracellularis PHE/MN1-00 4059562 YP_595056.1 CDS kdtA NC_008011.1 853157 854476 R 3-deoxy-D-manno-octulosonic-acid transferase complement(853157..854476) Lawsonia intracellularis PHE/MN1-00 4059675 YP_595057.1 CDS ddlA NC_008011.1 854481 855389 R D-alanine-D-alanine ligase and related ATP-grasp enzymes complement(854481..855389) Lawsonia intracellularis PHE/MN1-00 4060371 YP_595058.1 CDS LI0683 NC_008011.1 855346 855987 R hypothetical protein complement(855346..855987) Lawsonia intracellularis PHE/MN1-00 4059563 YP_595059.1 CDS LI0684 NC_008011.1 856632 857084 R acetyltransferase complement(856632..857084) Lawsonia intracellularis PHE/MN1-00 4059564 YP_595060.1 CDS dnaJ NC_008011.1 858662 859786 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(858662..859786) Lawsonia intracellularis PHE/MN1-00 4060378 YP_595061.1 CDS pepA NC_008011.1 860201 861736 R leucyl aminopeptidase complement(860201..861736) Lawsonia intracellularis PHE/MN1-00 4060026 YP_595062.1 CDS LI0687 NC_008011.1 861756 863153 R response regulator complement(861756..863153) Lawsonia intracellularis PHE/MN1-00 4059317 YP_595063.1 CDS LI0688 NC_008011.1 863417 865222 D Outer membrane protein 863417..865222 Lawsonia intracellularis PHE/MN1-00 4059318 YP_595064.1 CDS grsT NC_008011.1 865222 869370 D hypothetical protein 865222..869370 Lawsonia intracellularis PHE/MN1-00 4060255 YP_595065.1 CDS LI0690 NC_008011.1 869436 869954 R hypothetical protein complement(869436..869954) Lawsonia intracellularis PHE/MN1-00 4059319 YP_595066.1 CDS pal NC_008011.1 870411 870899 R Outer membrane protein and related peptidoglycan-associated (lipo)proteins complement(870411..870899) Lawsonia intracellularis PHE/MN1-00 4060021 YP_595067.1 CDS tolB NC_008011.1 871045 872403 R periplasmic component of the Tol biopolymer transport system complement(871045..872403) Lawsonia intracellularis PHE/MN1-00 4059828 YP_595068.1 CDS LI0693 NC_008011.1 872867 873820 R colicin uptake membrane protein complement(872867..873820) Lawsonia intracellularis PHE/MN1-00 4059320 YP_595069.1 CDS exbD NC_008011.1 873921 874355 R biopolymer transport protein complement(873921..874355) Lawsonia intracellularis PHE/MN1-00 4059301 YP_595070.1 CDS tolQ NC_008011.1 874438 875115 R biopolymer transport proteins complement(874438..875115) Lawsonia intracellularis PHE/MN1-00 4059829 YP_595071.1 CDS rubY NC_008011.1 875739 876314 D rubrerythrin 875739..876314 Lawsonia intracellularis PHE/MN1-00 4059628 YP_595072.1 CDS rubA NC_008011.1 876328 876531 D rubredoxin 2 (Rd-2) 876328..876531 Lawsonia intracellularis PHE/MN1-00 4059627 YP_595073.1 CDS rfaF NC_008011.1 876635 877663 D ADP-heptose:LPS heptosyltransferase II 876635..877663 Lawsonia intracellularis PHE/MN1-00 4059948 YP_595074.1 CDS LI0699 NC_008011.1 877710 878720 D hypothetical protein 877710..878720 Lawsonia intracellularis PHE/MN1-00 4059321 YP_595075.1 CDS LI0700 NC_008011.1 878912 879499 R TPR repeat-containing protein complement(878912..879499) Lawsonia intracellularis PHE/MN1-00 4059322 YP_595076.1 CDS uvrC NC_008011.1 879685 881550 R nuclease subunit of the excinuclease complex complement(879685..881550) Lawsonia intracellularis PHE/MN1-00 4059608 YP_595077.1 CDS maf NC_008011.1 881559 882254 R nucleotide-binding protein implicated in inhibition of septum formation complement(881559..882254) Lawsonia intracellularis PHE/MN1-00 4060144 YP_595078.1 CDS LI0703 NC_008011.1 882513 883592 D exopolyphosphatase-like protein 882513..883592 Lawsonia intracellularis PHE/MN1-00 4059323 YP_595079.1 CDS asnC NC_008011.1 883675 885042 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(883675..885042) Lawsonia intracellularis PHE/MN1-00 4059385 YP_595080.1 CDS LI0705 NC_008011.1 885106 885795 R DedA family protein complement(885106..885795) Lawsonia intracellularis PHE/MN1-00 4059324 YP_595081.1 CDS LI0706 NC_008011.1 885880 889188 R hypothetical protein complement(885880..889188) Lawsonia intracellularis PHE/MN1-00 4059325 YP_595082.1 CDS hypF NC_008011.1 889587 891977 R hydrogenase maturation factor complement(889587..891977) Lawsonia intracellularis PHE/MN1-00 4059665 YP_595083.1 CDS LI0708 NC_008011.1 892189 893016 D protein-disulfide isomerase 892189..893016 Lawsonia intracellularis PHE/MN1-00 4059326 YP_595084.1 CDS ribF NC_008011.1 893127 894170 D FAD synthase 893127..894170 Lawsonia intracellularis PHE/MN1-00 4059899 YP_595085.1 CDS fliC NC_008011.1 894199 895080 D flagellin-like protein 894199..895080 Lawsonia intracellularis PHE/MN1-00 4059736 YP_595086.1 CDS LI0711 NC_008011.1 895227 895730 R colicin V production membrane protein complement(895227..895730) Lawsonia intracellularis PHE/MN1-00 4059327 YP_595087.1 CDS pyrD NC_008011.1 896405 897349 R dihydroorotate dehydrogenase complement(896405..897349) Lawsonia intracellularis PHE/MN1-00 4059966 YP_595088.1 CDS pyrDII NC_008011.1 897346 898152 R 2-polyprenylphenol 6-hydroxylase complement(897346..898152) Lawsonia intracellularis PHE/MN1-00 4059967 YP_595089.1 CDS argJ NC_008011.1 898390 899574 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 898390..899574 Lawsonia intracellularis PHE/MN1-00 4059382 YP_595090.1 CDS rluD NC_008011.1 899739 900704 D pseudouridylate synthase 899739..900704 Lawsonia intracellularis PHE/MN1-00 4059903 YP_595091.1 CDS gln NC_008011.1 900834 901616 D amino acid ABC transporter substrate-binding protein 900834..901616 Lawsonia intracellularis PHE/MN1-00 4060329 YP_595092.1 CDS glnP NC_008011.1 901672 902370 D ABC-type amino acid transport system, permease component 901672..902370 Lawsonia intracellularis PHE/MN1-00 4060212 YP_595093.1 CDS glnQ NC_008011.1 902381 903256 D ABC-type polar amino acid transport system, ATPase component 902381..903256 Lawsonia intracellularis PHE/MN1-00 4060215 YP_595094.1 CDS LI0719 NC_008011.1 903258 903944 D ABC-type amino acid transport system, permease component 903258..903944 Lawsonia intracellularis PHE/MN1-00 4059328 YP_595095.1 CDS lepA NC_008011.1 903994 905814 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 903994..905814 Lawsonia intracellularis PHE/MN1-00 4059681 YP_595096.1 CDS LI0721 NC_008011.1 905910 906278 R transporter complement(905910..906278) Lawsonia intracellularis PHE/MN1-00 4059329 YP_595097.1 CDS LI0722 NC_008011.1 906849 908045 R hypothetical protein complement(906849..908045) Lawsonia intracellularis PHE/MN1-00 4059330 YP_595098.1 CDS mltA NC_008011.1 908182 909393 R membrane-bound lytic murein transglycosylase complement(908182..909393) Lawsonia intracellularis PHE/MN1-00 4060120 YP_595099.1 CDS LI0724 NC_008011.1 909409 909858 D thioesterase 909409..909858 Lawsonia intracellularis PHE/MN1-00 4059331 YP_595100.1 CDS hisB NC_008011.1 910107 910928 R PHP family histidinol phosphatase/hydrolase complement(910107..910928) Lawsonia intracellularis PHE/MN1-00 4059684 YP_595101.2 CDS metK NC_008011.1 911020 912195 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(911020..912195) Lawsonia intracellularis PHE/MN1-00 4060115 YP_595102.1 CDS LI0727 NC_008011.1 912401 912991 D hypothetical protein 912401..912991 Lawsonia intracellularis PHE/MN1-00 4059332 YP_595103.1 CDS lytB NC_008011.1 912997 913881 D ribosomal protein S1 912997..913881 Lawsonia intracellularis PHE/MN1-00 4060141 YP_595104.1 CDS cheV NC_008011.1 913946 914896 D chemotaxis signal transduction protein 913946..914896 Lawsonia intracellularis PHE/MN1-00 4060418 YP_595105.1 CDS ugd NC_008011.1 914956 916287 R UDP-glucose 6-dehydrogenase complement(914956..916287) Lawsonia intracellularis PHE/MN1-00 4059511 YP_595106.1 CDS acpS NC_008011.1 916424 916801 D holo-ACP synthase 916424..916801 Lawsonia intracellularis PHE/MN1-00 4060340 YP_595107.1 CDS hslV NC_008011.1 916828 917361 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 916828..917361 Lawsonia intracellularis PHE/MN1-00 4059690 YP_595108.1 CDS LI0733 NC_008011.1 917632 918429 D amino acid ABC transporter substrate-binding protein 917632..918429 Lawsonia intracellularis PHE/MN1-00 4059333 YP_595109.1 CDS LI0734 NC_008011.1 918588 919070 D hypothetical protein 918588..919070 Lawsonia intracellularis PHE/MN1-00 4059334 YP_595110.1 CDS ychB NC_008011.1 919170 920087 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 919170..920087 Lawsonia intracellularis PHE/MN1-00 4059619 YP_595111.1 CDS prsA NC_008011.1 920202 921167 D phosphoribosylpyrophosphate synthetase 920202..921167 Lawsonia intracellularis PHE/MN1-00 4059983 YP_595112.1 CDS LI0737 NC_008011.1 921211 921804 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 921211..921804 Lawsonia intracellularis PHE/MN1-00 4059335 YP_595113.1 CDS LI0738 NC_008011.1 921880 922485 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 921880..922485 Lawsonia intracellularis PHE/MN1-00 4059336 YP_595114.1 CDS LI0739 NC_008011.1 922741 923433 D hypothetical protein 922741..923433 Lawsonia intracellularis PHE/MN1-00 4059337 YP_595115.1 CDS flgF NC_008011.1 923583 924377 D flagellar basal body rod protein 923583..924377 Lawsonia intracellularis PHE/MN1-00 4059724 YP_595116.1 CDS flgG NC_008011.1 924392 925177 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 924392..925177 Lawsonia intracellularis PHE/MN1-00 4059725 YP_595117.1 CDS LI0742 NC_008011.1 925203 926186 D hypothetical protein 925203..926186 Lawsonia intracellularis PHE/MN1-00 4059338 YP_595118.1 CDS flgH NC_008011.1 926204 926896 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar basal body L-ring protein 926204..926896 Lawsonia intracellularis PHE/MN1-00 4059726 YP_595119.1 CDS flgI NC_008011.1 926942 928081 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 926942..928081 Lawsonia intracellularis PHE/MN1-00 4059727 YP_595120.1 CDS flgJ NC_008011.1 928086 928769 D membrane proteins related to metalloendopeptidases 928086..928769 Lawsonia intracellularis PHE/MN1-00 4059728 YP_595121.1 CDS LI0746 NC_008011.1 928976 929506 D hypothetical protein 928976..929506 Lawsonia intracellularis PHE/MN1-00 4059339 YP_595122.1 CDS flgK NC_008011.1 929506 931623 D flagellar hook-associated protein 929506..931623 Lawsonia intracellularis PHE/MN1-00 4059729 YP_595123.1 CDS flgL NC_008011.1 931633 933210 D flagellin-like protein 931633..933210 Lawsonia intracellularis PHE/MN1-00 4059730 YP_595124.1 CDS LI0749 NC_008011.1 933304 933993 D binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 933304..933993 Lawsonia intracellularis PHE/MN1-00 4059340 YP_595125.1 CDS LI0750 NC_008011.1 934221 935801 D hypothetical protein 934221..935801 Lawsonia intracellularis PHE/MN1-00 4059341 YP_595126.1 CDS LI0751 NC_008011.1 935839 937368 R Mg chelatase-related protein complement(935839..937368) Lawsonia intracellularis PHE/MN1-00 4059342 YP_595127.1 CDS LI0752 NC_008011.1 937365 939059 R Sulfate transporter family protein complement(937365..939059) Lawsonia intracellularis PHE/MN1-00 4059343 YP_595128.1 CDS glnP NC_008011.1 939166 939858 R ABC-type amino acid transport system, permease component complement(939166..939858) Lawsonia intracellularis PHE/MN1-00 4060213 YP_595129.1 CDS glnH NC_008011.1 939981 940730 R amino acid ABC transporter substrate-binding protein complement(939981..940730) Lawsonia intracellularis PHE/MN1-00 4060210 YP_595130.1 CDS rpsA NC_008011.1 941271 942995 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(941271..942995) Lawsonia intracellularis PHE/MN1-00 4060142 YP_595131.1 CDS rnhA NC_008011.1 943310 943795 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(943310..943795) Lawsonia intracellularis PHE/MN1-00 4059909 YP_595132.1 CDS menA NC_008011.1 943971 944864 R hypothetical protein complement(943971..944864) Lawsonia intracellularis PHE/MN1-00 4060149 YP_595133.1 CDS LI0758 NC_008011.1 944976 945602 R hypothetical protein complement(944976..945602) Lawsonia intracellularis PHE/MN1-00 4059344 YP_595134.1 CDS menA NC_008011.1 945599 946513 R hypothetical protein complement(945599..946513) Lawsonia intracellularis PHE/MN1-00 4060150 YP_595135.1 CDS tmk NC_008011.1 946612 947238 R thymidylate kinase complement(946612..947238) Lawsonia intracellularis PHE/MN1-00 4059827 YP_595136.1 CDS cbf1 NC_008011.1 947223 948281 R HD-superfamily hydrolase complement(947223..948281) Lawsonia intracellularis PHE/MN1-00 4060404 YP_595137.1 CDS surE NC_008011.1 948405 949160 D acid phosphatase 948405..949160 Lawsonia intracellularis PHE/MN1-00 4059808 YP_595138.1 CDS fba NC_008011.1 949353 950276 D fructose/tagatose bisphosphate aldolase 949353..950276 Lawsonia intracellularis PHE/MN1-00 4059308 YP_595139.1 CDS gapA NC_008011.1 950386 951387 D glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase 950386..951387 Lawsonia intracellularis PHE/MN1-00 4060318 YP_595140.1 CDS LI0765 NC_008011.1 951412 952311 R hypothetical protein complement(951412..952311) Lawsonia intracellularis PHE/MN1-00 4059345 YP_595141.1 CDS fmt NC_008011.1 952368 953336 R methionyl-tRNA formyltransferase complement(952368..953336) Lawsonia intracellularis PHE/MN1-00 4059748 YP_595142.1 CDS def NC_008011.1 953333 953848 R N-formylmethionyl-tRNA deformylase complement(953333..953848) Lawsonia intracellularis PHE/MN1-00 4060372 YP_595143.1 CDS nifr3 NC_008011.1 954008 955000 D tRNA-dihydrouridine synthase 954008..955000 Lawsonia intracellularis PHE/MN1-00 4060057 YP_595144.1 CDS LI0769 NC_008011.1 955017 955769 R hypothetical protein complement(955017..955769) Lawsonia intracellularis PHE/MN1-00 4059346 YP_595145.1 CDS LI0770 NC_008011.1 955760 956341 R 5-formyltetrahydrofolate cyclo-ligase complement(955760..956341) Lawsonia intracellularis PHE/MN1-00 4059347 YP_595146.1 CDS rne NC_008011.1 957340 959340 D ribonucleases G and E 957340..959340 Lawsonia intracellularis PHE/MN1-00 4059908 YP_595147.1 CDS LI0772 NC_008011.1 959344 959937 D hypothetical protein 959344..959937 Lawsonia intracellularis PHE/MN1-00 4059348 YP_595148.1 CDS kefC NC_008011.1 959970 961946 R Kef-type K+ transport systems, membrane components complement(959970..961946) Lawsonia intracellularis PHE/MN1-00 4059677 YP_595149.1 CDS trkA NC_008011.1 962215 963630 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 962215..963630 Lawsonia intracellularis PHE/MN1-00 4059833 YP_595150.1 CDS trkH NC_008011.1 963721 965187 D Trk-type K+ transport systems, membrane components 963721..965187 Lawsonia intracellularis PHE/MN1-00 4059834 YP_595151.1 CDS psd NC_008011.1 965279 965941 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 965279..965941 Lawsonia intracellularis PHE/MN1-00 4059984 YP_595152.1 CDS LI0777 NC_008011.1 966003 966752 D phosphatidylserine synthase 966003..966752 Lawsonia intracellularis PHE/MN1-00 4059349 YP_595153.1 CDS nth NC_008011.1 966810 967460 R endonuclease III complement(966810..967460) Lawsonia intracellularis PHE/MN1-00 4060065 YP_595154.1 CDS cutA NC_008011.1 967580 967900 D divalent cation tolerance protein 967580..967900 Lawsonia intracellularis PHE/MN1-00 4060437 YP_595155.1 CDS fruK NC_008011.1 967901 968842 D ribokinase family sugar kinase 967901..968842 Lawsonia intracellularis PHE/MN1-00 4059753 YP_595156.1 CDS LI0781 NC_008011.1 969129 970853 D 5-enolpyruvylshikimate-3-phosphate synthase 969129..970853 Lawsonia intracellularis PHE/MN1-00 4059350 YP_595157.1 CDS thiD NC_008011.1 970873 971706 D hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 970873..971706 Lawsonia intracellularis PHE/MN1-00 4059817 YP_595158.1 CDS LI0783 NC_008011.1 972160 972975 R hypothetical protein complement(972160..972975) Lawsonia intracellularis PHE/MN1-00 4059351 YP_595159.1 CDS gyrA NC_008011.1 973029 975491 R Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit complement(973029..975491) Lawsonia intracellularis PHE/MN1-00 4060258 YP_595160.1 CDS gyrB NC_008011.1 975610 978009 R Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit complement(975610..978009) Lawsonia intracellularis PHE/MN1-00 4060259 YP_595161.1 CDS dnaN NC_008011.1 978042 979193 R DNA polymerase sliding clamp subunit (PCNA homolog) complement(978042..979193) Lawsonia intracellularis PHE/MN1-00 4060381 YP_595162.1 CDS dnaA NC_008011.1 979314 980636 R DNA replication initiation ATPase complement(979314..980636) Lawsonia intracellularis PHE/MN1-00 4060375 YP_595163.1 CDS LI0788 NC_008011.1 980888 982222 D membrane proteins related to metalloendopeptidases 980888..982222 Lawsonia intracellularis PHE/MN1-00 4059352 YP_595164.1 CDS queA NC_008011.1 982255 983355 D S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) 982255..983355 Lawsonia intracellularis PHE/MN1-00 4059935 YP_595165.1 CDS vorB NC_008011.1 984330 985391 D catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; 2-ketoisovalerate ferredoxin reductase 984330..985391 Lawsonia intracellularis PHE/MN1-00 4059612 YP_595166.1 CDS porB NC_008011.1 985391 986194 D ferredoxin oxidoreductases, beta subunit 985391..986194 Lawsonia intracellularis PHE/MN1-00 4060005 YP_595167.1 CDS porB NC_008011.1 986196 986738 D ferredoxin oxidoreductases, gamma subunit 986196..986738 Lawsonia intracellularis PHE/MN1-00 4060006 YP_595168.1 CDS LI0793 NC_008011.1 987288 988580 D FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) 987288..988580 Lawsonia intracellularis PHE/MN1-00 4059353 YP_595169.1 CDS clpP NC_008011.1 988737 989366 D protease subunit of ATP-dependent Clp proteases 988737..989366 Lawsonia intracellularis PHE/MN1-00 4060426 YP_595170.1 CDS clpX NC_008011.1 989642 990895 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 989642..990895 Lawsonia intracellularis PHE/MN1-00 4060427 YP_595171.1 CDS lon NC_008011.1 990983 993436 D ATP-dependent protease 990983..993436 Lawsonia intracellularis PHE/MN1-00 4059662 YP_595172.1 CDS LI0797 NC_008011.1 993461 993847 R hypothetical protein complement(993461..993847) Lawsonia intracellularis PHE/MN1-00 4059354 YP_595173.1 CDS LI0798 NC_008011.1 994282 995271 D hypothetical protein 994282..995271 Lawsonia intracellularis PHE/MN1-00 4059355 YP_595174.1 CDS LI0799 NC_008011.1 995278 995916 R hypothetical protein complement(995278..995916) Lawsonia intracellularis PHE/MN1-00 4059455 YP_595175.1 CDS LI0800 NC_008011.1 995965 996681 R hypothetical protein complement(995965..996681) Lawsonia intracellularis PHE/MN1-00 4059456 YP_595176.1 CDS glmU NC_008011.1 996842 998215 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 996842..998215 Lawsonia intracellularis PHE/MN1-00 4060328 YP_595177.1 CDS LI0802 NC_008011.1 999188 1000750 D protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 999188..1000750 Lawsonia intracellularis PHE/MN1-00 4059457 YP_595178.1 CDS LI0803 NC_008011.1 1000833 1001591 D hypothetical protein 1000833..1001591 Lawsonia intracellularis PHE/MN1-00 4059458 YP_595179.1 CDS LI0804 NC_008011.1 1001682 1002140 R hypothetical protein complement(1001682..1002140) Lawsonia intracellularis PHE/MN1-00 4059459 YP_595180.1 CDS LI0805 NC_008011.1 1002133 1002810 R hypothetical protein complement(1002133..1002810) Lawsonia intracellularis PHE/MN1-00 4059460 YP_595181.1 CDS menE NC_008011.1 1002865 1003953 R O-succinylbenzoic acid--CoA ligase complement(1002865..1003953) Lawsonia intracellularis PHE/MN1-00 4060113 YP_595182.1 CDS menB NC_008011.1 1004052 1004873 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(1004052..1004873) Lawsonia intracellularis PHE/MN1-00 4060112 YP_595183.1 CDS comA NC_008011.1 1004883 1005317 R hydrolase, haloacid dehalogenase-like hydrolase complement(1004883..1005317) Lawsonia intracellularis PHE/MN1-00 4060432 YP_595184.1 CDS LI0809 NC_008011.1 1005673 1006062 R hypothetical protein complement(1005673..1006062) Lawsonia intracellularis PHE/MN1-00 4059461 YP_595185.1 CDS LI0810 NC_008011.1 1006385 1007098 D integral membrane protein, interacts with FtsH 1006385..1007098 Lawsonia intracellularis PHE/MN1-00 4059462 YP_595186.1 CDS pit NC_008011.1 1007157 1008167 R phosphate/sulphate permeases complement(1007157..1008167) Lawsonia intracellularis PHE/MN1-00 4059999 YP_595187.1 CDS LI0812 NC_008011.1 1008160 1008795 R hypothetical protein complement(1008160..1008795) Lawsonia intracellularis PHE/MN1-00 4059463 YP_595188.1 CDS rluD NC_008011.1 1010184 1011809 D pseudouridylate synthase 1010184..1011809 Lawsonia intracellularis PHE/MN1-00 4059904 YP_595189.1 CDS soj NC_008011.1 1012019 1012804 D chromosome partitioning ATPase 1012019..1012804 Lawsonia intracellularis PHE/MN1-00 4059804 YP_595190.1 CDS spo0J NC_008011.1 1012884 1013843 D transcriptional regulator 1012884..1013843 Lawsonia intracellularis PHE/MN1-00 4059806 YP_595191.1 CDS LI0816 NC_008011.1 1013959 1014996 D ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase 1013959..1014996 Lawsonia intracellularis PHE/MN1-00 4059464 YP_595192.1 CDS hemN NC_008011.1 1015004 1016197 R coproporphyrinogen III oxidase-like protein complement(1015004..1016197) Lawsonia intracellularis PHE/MN1-00 4060265 YP_595193.1 CDS pyrB NC_008011.1 1016534 1017481 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1016534..1017481 Lawsonia intracellularis PHE/MN1-00 4059964 YP_595194.1 CDS pyrC NC_008011.1 1017493 1018764 D dihydroorotase-like protein 1017493..1018764 Lawsonia intracellularis PHE/MN1-00 4059965 YP_595195.1 CDS LI0820 NC_008011.1 1018869 1019642 R 2-keto-4-pentenoate hydratase complement(1018869..1019642) Lawsonia intracellularis PHE/MN1-00 4059465 YP_595196.1 CDS miaB NC_008011.1 1019930 1021303 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1019930..1021303 Lawsonia intracellularis PHE/MN1-00 4060119 YP_595197.1 CDS LI0822 NC_008011.1 1021458 1022141 D PHP family histidinol phosphatase/hydrolase 1021458..1022141 Lawsonia intracellularis PHE/MN1-00 4059466 YP_595198.1 CDS pepQ NC_008011.1 1022176 1023267 D Xaa-Pro aminopeptidase 1022176..1023267 Lawsonia intracellularis PHE/MN1-00 4060029 YP_595199.1 CDS LI0824 NC_008011.1 1023291 1024349 D glycosyltransferase 1023291..1024349 Lawsonia intracellularis PHE/MN1-00 4059467 YP_595200.1 CDS LI0825 NC_008011.1 1024378 1025664 D Lipid A core-O-antigen ligase and related enzymes 1024378..1025664 Lawsonia intracellularis PHE/MN1-00 4059468 YP_595201.1 CDS rpmB NC_008011.1 1025679 1025888 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1025679..1025888) Lawsonia intracellularis PHE/MN1-00 4059840 YP_595202.1 CDS LI0827 NC_008011.1 1026067 1028082 D lipoprotein 1026067..1028082 Lawsonia intracellularis PHE/MN1-00 4059469 YP_595203.1 CDS gpsA NC_008011.1 1028105 1029172 R glycerol-3-phosphate dehydrogenase complement(1028105..1029172) Lawsonia intracellularis PHE/MN1-00 4060252 YP_595204.1 CDS potA NC_008011.1 1029763 1030869 D functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1029763..1030869 Lawsonia intracellularis PHE/MN1-00 4060007 YP_595205.1 CDS potB NC_008011.1 1030856 1031740 D ABC-type spermidine/putrescine transport system, permease component I 1030856..1031740 Lawsonia intracellularis PHE/MN1-00 4060008 YP_595206.1 CDS potC NC_008011.1 1031740 1032516 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1031740..1032516 Lawsonia intracellularis PHE/MN1-00 4060009 YP_595207.1 CDS potD NC_008011.1 1032574 1033626 D spermidine/putrescine-binding periplasmic protein 1032574..1033626 Lawsonia intracellularis PHE/MN1-00 4060010 YP_595208.1 CDS LI0833 NC_008011.1 1033802 1035070 R hypothetical protein complement(1033802..1035070) Lawsonia intracellularis PHE/MN1-00 4059470 YP_595209.1 CDS LI0834 NC_008011.1 1035090 1035533 R hypothetical protein complement(1035090..1035533) Lawsonia intracellularis PHE/MN1-00 4059471 YP_595210.1 CDS LI0835 NC_008011.1 1035578 1036222 R hypothetical protein complement(1035578..1036222) Lawsonia intracellularis PHE/MN1-00 4059472 YP_595211.1 CDS LI0836 NC_008011.1 1036458 1037198 D transcriptional regulator 1036458..1037198 Lawsonia intracellularis PHE/MN1-00 4059473 YP_595212.1 CDS LI0837 NC_008011.1 1037498 1040206 D hypothetical protein 1037498..1040206 Lawsonia intracellularis PHE/MN1-00 4059395 YP_595213.1 CDS murA NC_008011.1 1040246 1041496 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1040246..1041496) Lawsonia intracellularis PHE/MN1-00 4060074 YP_595214.1 CDS xthA NC_008011.1 1041779 1042558 R exonuclease III complement(1041779..1042558) Lawsonia intracellularis PHE/MN1-00 4059615 YP_595215.1 CDS LI0840 NC_008011.1 1042878 1043369 R hypothetical protein complement(1042878..1043369) Lawsonia intracellularis PHE/MN1-00 4059396 YP_595216.1 CDS LI0841 NC_008011.1 1043947 1044681 R invasin complement(1043947..1044681) Lawsonia intracellularis PHE/MN1-00 4059397 YP_595217.1 CDS katE NC_008011.1 1045546 1047813 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1045546..1047813 Lawsonia intracellularis PHE/MN1-00 4059673 YP_595218.1 CDS tsr NC_008011.1 1048872 1050629 D methyl-accepting chemotaxis protein 1048872..1050629 Lawsonia intracellularis PHE/MN1-00 4059505 YP_595219.1 CDS LI0844 NC_008011.1 1050746 1052017 R tRNA and rRNA cytosine-C5-methylases complement(1050746..1052017) Lawsonia intracellularis PHE/MN1-00 4059398 YP_595220.1 CDS LI0845 NC_008011.1 1052160 1053803 D hypothetical protein 1052160..1053803 Lawsonia intracellularis PHE/MN1-00 4059399 YP_595221.1 CDS LI0846 NC_008011.1 1053988 1055109 D lipopolysaccharide core biosynthesis protein RfaG (glucosyltransferase I) 1053988..1055109 Lawsonia intracellularis PHE/MN1-00 4059400 YP_595222.1 CDS LI0847 NC_008011.1 1055274 1056068 D hypothetical protein 1055274..1056068 Lawsonia intracellularis PHE/MN1-00 4059401 YP_595223.1 CDS gidA NC_008011.1 1056140 1057477 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(1056140..1057477) Lawsonia intracellularis PHE/MN1-00 4060322 YP_595224.1 CDS LI0849 NC_008011.1 1057662 1058297 R HD superfamily hydrolase complement(1057662..1058297) Lawsonia intracellularis PHE/MN1-00 4059402 YP_595225.1 CDS LI0850 NC_008011.1 1058349 1059566 R hypothetical protein complement(1058349..1059566) Lawsonia intracellularis PHE/MN1-00 4059403 YP_595226.1 CDS LI0851 NC_008011.1 1059742 1060068 D NAD(P)H-dependent flavin reductase 1059742..1060068 Lawsonia intracellularis PHE/MN1-00 4059404 YP_595227.1 CDS LI0852 NC_008011.1 1060120 1060419 D NAD(P)H nitroreductase 1060120..1060419 Lawsonia intracellularis PHE/MN1-00 4059405 YP_595228.1 CDS LI0853 NC_008011.1 1060422 1060829 R redox protein, regulator of disulfide bond formation complement(1060422..1060829) Lawsonia intracellularis PHE/MN1-00 4059406 YP_595229.1 CDS fliI NC_008011.1 1062640 1063959 R flagellar biosynthesis/type III secretory pathway ATPase complement(1062640..1063959) Lawsonia intracellularis PHE/MN1-00 4059741 YP_595230.1 CDS LI0855 NC_008011.1 1063984 1065429 R flagellar biosynthesis/type III secretory pathway protein complement(1063984..1065429) Lawsonia intracellularis PHE/MN1-00 4059407 YP_595231.1 CDS fliG NC_008011.1 1065476 1066471 R flagellar motor switch protein complement(1065476..1066471) Lawsonia intracellularis PHE/MN1-00 4059740 YP_595232.1 CDS fliF NC_008011.1 1066878 1068542 R flagellar biosynthesis/type III secretory pathway lipoprotein complement(1066878..1068542) Lawsonia intracellularis PHE/MN1-00 4059739 YP_595233.1 CDS fliE NC_008011.1 1068655 1069002 R flagellar hook-basal body protein complement(1068655..1069002) Lawsonia intracellularis PHE/MN1-00 4059738 YP_595234.1 CDS flgC NC_008011.1 1069051 1069491 R flagellar basal body rod protein complement(1069051..1069491) Lawsonia intracellularis PHE/MN1-00 4059316 YP_595235.1 CDS flgB NC_008011.1 1069494 1069907 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgB complement(1069494..1069907) Lawsonia intracellularis PHE/MN1-00 4059315 YP_595236.1 CDS cbiO NC_008011.1 1070196 1070954 R ABC-type cobalt transport system, ATPase component complement(1070196..1070954) Lawsonia intracellularis PHE/MN1-00 4060406 YP_595237.1 CDS LI0862 NC_008011.1 1070963 1071709 R hypothetical protein complement(1070963..1071709) Lawsonia intracellularis PHE/MN1-00 4059408 YP_595238.1 CDS cbiM NC_008011.1 1071699 1072334 R catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM complement(1071699..1072334) Lawsonia intracellularis PHE/MN1-00 4060405 YP_595239.1 CDS LI0864 NC_008011.1 1072321 1072818 R hypothetical protein complement(1072321..1072818) Lawsonia intracellularis PHE/MN1-00 4059409 YP_595240.1 CDS mviN NC_008011.1 1073007 1074569 R uncharacterized membrane protein, virulence factor complement(1073007..1074569) Lawsonia intracellularis PHE/MN1-00 4060086 YP_595241.1 CDS LI0866 NC_008011.1 1074655 1076736 R membrane metal-binding protein complement(1074655..1076736) Lawsonia intracellularis PHE/MN1-00 4059410 YP_595242.1 CDS murI NC_008011.1 1077738 1078598 R glutamate racemase complement(1077738..1078598) Lawsonia intracellularis PHE/MN1-00 4060080 YP_595243.1 CDS rluB NC_008011.1 1078883 1079695 R 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases complement(1078883..1079695) Lawsonia intracellularis PHE/MN1-00 4059902 YP_595244.1 CDS LI0869 NC_008011.1 1079867 1081684 D ABC-type multidrug transport system, ATPase and permease components 1079867..1081684 Lawsonia intracellularis PHE/MN1-00 4059411 YP_595245.1 CDS LI0870 NC_008011.1 1081659 1082303 D hypothetical protein 1081659..1082303 Lawsonia intracellularis PHE/MN1-00 4059412 YP_595246.1 CDS htrB NC_008011.1 1082307 1083191 D acyltransferase 1082307..1083191 Lawsonia intracellularis PHE/MN1-00 4059693 YP_595247.1 CDS LI0872 NC_008011.1 1083991 1085361 R hypothetical protein complement(1083991..1085361) Lawsonia intracellularis PHE/MN1-00 4059413 YP_595248.1 CDS LI0873 NC_008011.1 1085499 1086062 R ACT domain-containing protein complement(1085499..1086062) Lawsonia intracellularis PHE/MN1-00 4059414 YP_595249.1 CDS LI0874 NC_008011.1 1086267 1088042 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1086267..1088042 Lawsonia intracellularis PHE/MN1-00 4059356 YP_595250.1 CDS LI0875 NC_008011.1 1088081 1088974 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1088081..1088974 Lawsonia intracellularis PHE/MN1-00 4059357 YP_595251.1 CDS LI0876 NC_008011.1 1088986 1090329 R tRNA and rRNA cytosine-C5-methylases complement(1088986..1090329) Lawsonia intracellularis PHE/MN1-00 4059358 YP_595252.1 CDS atoC NC_008011.1 1090388 1091761 R response regulator complement(1090388..1091761) Lawsonia intracellularis PHE/MN1-00 4059389 YP_595253.1 CDS atoS NC_008011.1 1091827 1093269 R Signal transduction histidine kinase complement(1091827..1093269) Lawsonia intracellularis PHE/MN1-00 4059390 YP_595254.1 CDS pgi NC_008011.1 1093271 1094605 R glucose-6-phosphate isomerase complement(1093271..1094605) Lawsonia intracellularis PHE/MN1-00 4060032 YP_595255.1 CDS sfsA NC_008011.1 1095072 1095860 D DNA-binding protein, stimulates sugar fermentation 1095072..1095860 Lawsonia intracellularis PHE/MN1-00 4059799 YP_595256.1 CDS LI0881 NC_008011.1 1095872 1096972 R permease complement(1095872..1096972) Lawsonia intracellularis PHE/MN1-00 4059359 YP_595257.1 CDS LI0882 NC_008011.1 1096969 1098123 R permease complement(1096969..1098123) Lawsonia intracellularis PHE/MN1-00 4059360 YP_595258.1 CDS LI0883 NC_008011.1 1098346 1099038 R Zn-dependent hydrolase complement(1098346..1099038) Lawsonia intracellularis PHE/MN1-00 4059361 YP_595259.1 CDS selB NC_008011.1 1099356 1101281 R selenocysteine-specific translation elongation factor complement(1099356..1101281) Lawsonia intracellularis PHE/MN1-00 4059641 YP_595260.1 CDS LI0885 NC_008011.1 1101390 1102847 R Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases complement(1101390..1102847) Lawsonia intracellularis PHE/MN1-00 4059362 YP_595261.1 CDS LI0886 NC_008011.1 <1102873 >1103156 R glutamyl-tRNA (Gln) amidotransferase subunit C complement(<1102873..>1103156) Lawsonia intracellularis PHE/MN1-00 4059363 YP_595262.1 CDS LI0887 NC_008011.1 1103384 1103869 R hypothetical protein complement(1103384..1103869) Lawsonia intracellularis PHE/MN1-00 4059364 YP_595263.1 CDS LI0888 NC_008011.1 1104132 1104584 D universal stress protein UspA-like nucleotide-binding protein 1104132..1104584 Lawsonia intracellularis PHE/MN1-00 4059365 YP_595264.1 CDS LI0889 NC_008011.1 1105139 1105771 R hypothetical protein complement(1105139..1105771) Lawsonia intracellularis PHE/MN1-00 4059366 YP_595265.1 CDS LI0890 NC_008011.1 1106149 1110171 R hypothetical protein complement(1106149..1110171) Lawsonia intracellularis PHE/MN1-00 4059367 YP_595266.1 CDS LI0891 NC_008011.1 1111143 1111616 D hypothetical protein 1111143..1111616 Lawsonia intracellularis PHE/MN1-00 4059368 YP_595267.1 CDS lnt NC_008011.1 1111705 1113402 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 1111705..1113402 Lawsonia intracellularis PHE/MN1-00 4059658 YP_595268.1 CDS LI0893 NC_008011.1 1113451 1114539 D protein chain release factor B 1113451..1114539 Lawsonia intracellularis PHE/MN1-00 4059369 YP_595269.1 CDS himD NC_008011.1 1114982 1115257 D nucleoid DNA-binding protein 1114982..1115257 Lawsonia intracellularis PHE/MN1-00 4059683 YP_595270.1 CDS dapF NC_008011.1 1115585 1116430 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1115585..1116430 Lawsonia intracellularis PHE/MN1-00 4060370 YP_595271.1 CDS dapA NC_008011.1 1116477 1117382 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1116477..1117382 Lawsonia intracellularis PHE/MN1-00 4060368 YP_595272.1 CDS araJ NC_008011.1 1117584 1118747 D member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 1117584..1118747 Lawsonia intracellularis PHE/MN1-00 4059375 YP_595273.1 CDS tatD NC_008011.1 1118929 1119711 D Mg-dependent DNase 1118929..1119711 Lawsonia intracellularis PHE/MN1-00 4059811 YP_595274.1 CDS LI0899 NC_008011.1 1119740 1120381 R hypothetical protein complement(1119740..1120381) Lawsonia intracellularis PHE/MN1-00 4059370 YP_595275.1 CDS LI0900 NC_008011.1 1120638 1121039 D metal-dependent hydrolase 1120638..1121039 Lawsonia intracellularis PHE/MN1-00 4059371 YP_595276.1 CDS dsr NC_008011.1 1121253 1121570 D sulfite reductase, dissimilatory-type gamma subunit 1121253..1121570 Lawsonia intracellularis PHE/MN1-00 4060385 YP_595277.1 CDS LI0902 NC_008011.1 1121916 1122938 D outer membrane protein 1121916..1122938 Lawsonia intracellularis PHE/MN1-00 4059372 YP_595278.1 CDS LI0903 NC_008011.1 1122971 1123441 D hypothetical protein 1122971..1123441 Lawsonia intracellularis PHE/MN1-00 4059373 YP_595279.1 CDS rpoB NC_008011.1 1123545 1127711 R DNA-directed RNA polymerase, beta subunit/140 kD subunit complement(1123545..1127711) Lawsonia intracellularis PHE/MN1-00 4059842 YP_595280.1 CDS rpoB NC_008011.1 1127787 1131908 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1127787..1131908) Lawsonia intracellularis PHE/MN1-00 4059843 YP_595281.1 CDS hemL NC_008011.1 1132246 1133538 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(1132246..1133538) Lawsonia intracellularis PHE/MN1-00 4060263 YP_595282.1 CDS nirH NC_008011.1 1133538 1134038 R transcriptional regulators complement(1133538..1134038) Lawsonia intracellularis PHE/MN1-00 4060059 YP_595283.1 CDS hypD NC_008011.1 1134626 1135717 D hydrogenase maturation factor 1134626..1135717 Lawsonia intracellularis PHE/MN1-00 4059663 YP_003856777.1 CDS LI_1200 NC_008011.1 1136154 1136372 R translation initiation factor IF-1 complement(1136154..1136372) Lawsonia intracellularis PHE/MN1-00 9711828 YP_595284.1 CDS lgt NC_008011.1 1136500 1137279 R prolipoprotein diacylglyceryl transferase complement(1136500..1137279) Lawsonia intracellularis PHE/MN1-00 4059646 YP_595285.1 CDS cmk NC_008011.1 1137481 1138158 R cytidylate kinase complement(1137481..1138158) Lawsonia intracellularis PHE/MN1-00 4060430 YP_595286.1 CDS LI0911 NC_008011.1 1138388 1139284 R hypothetical protein complement(1138388..1139284) Lawsonia intracellularis PHE/MN1-00 4059374 YP_595287.1 CDS dnaK NC_008011.1 1139678 1141579 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1139678..1141579 Lawsonia intracellularis PHE/MN1-00 4060380 YP_595288.1 CDS aspA NC_008011.1 1141712 1143127 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(1141712..1143127) Lawsonia intracellularis PHE/MN1-00 4059386 YP_595289.1 CDS dacC NC_008011.1 1143320 1144207 R D-alanyl-D-alanine carboxypeptidase complement(1143320..1144207) Lawsonia intracellularis PHE/MN1-00 4060444 YP_595290.1 CDS livE NC_008011.1 1144573 1145496 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1144573..1145496 Lawsonia intracellularis PHE/MN1-00 4059649 YP_595291.1 CDS dnaX NC_008011.1 1145527 1147251 D DNA polymerase III, gamma/tau subunits 1145527..1147251 Lawsonia intracellularis PHE/MN1-00 4060382 YP_595292.1 CDS LI0917 NC_008011.1 1147270 1147581 D hypothetical protein 1147270..1147581 Lawsonia intracellularis PHE/MN1-00 4059435 YP_595293.1 CDS recR NC_008011.1 1147646 1148257 D recombinational DNA repair protein 1147646..1148257 Lawsonia intracellularis PHE/MN1-00 4059944 YP_595294.1 CDS LI0919 NC_008011.1 1148418 1149008 R helicase family protein complement(1148418..1149008) Lawsonia intracellularis PHE/MN1-00 4059436 YP_595295.1 CDS LI0920 NC_008011.1 1149173 1150072 R membrane proteins related to metalloendopeptidases complement(1149173..1150072) Lawsonia intracellularis PHE/MN1-00 4059437 YP_595296.1 CDS purD NC_008011.1 1150886 1152172 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1150886..1152172 Lawsonia intracellularis PHE/MN1-00 4059992 YP_595297.1 CDS purK NC_008011.1 1152159 1152674 D phosphoribosylcarboxyaminoimidazole (NCAIR) mutase 1152159..1152674 Lawsonia intracellularis PHE/MN1-00 4059957 YP_595298.1 CDS lepB NC_008011.1 1152735 1153367 D Signal peptidase I 1152735..1153367 Lawsonia intracellularis PHE/MN1-00 4059682 YP_595299.1 CDS qacE NC_008011.1 1153381 1153701 R membrane transporters of cations and cationic drugs complement(1153381..1153701) Lawsonia intracellularis PHE/MN1-00 4059972 YP_595300.1 CDS qacE NC_008011.1 1153732 1154109 R membrane transporters of cations and cationic drugs complement(1153732..1154109) Lawsonia intracellularis PHE/MN1-00 4059973 YP_595301.1 CDS mdoB NC_008011.1 1154151 1156142 R hypothetical protein complement(1154151..1156142) Lawsonia intracellularis PHE/MN1-00 4060148 YP_595302.1 CDS mviN NC_008011.1 1156205 1157719 R uncharacterized membrane protein, virulence factor complement(1156205..1157719) Lawsonia intracellularis PHE/MN1-00 4060087 YP_595303.1 CDS tgt NC_008011.1 1157845 1158960 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1157845..1158960 Lawsonia intracellularis PHE/MN1-00 4059814 YP_595304.1 CDS LI0929 NC_008011.1 1159064 1160209 R cell wall biosynthesis glycosyltransferase complement(1159064..1160209) Lawsonia intracellularis PHE/MN1-00 4059438 YP_595305.1 CDS rplL NC_008011.1 1160320 1160706 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1160320..1160706) Lawsonia intracellularis PHE/MN1-00 4059884 YP_595306.1 CDS rplJ NC_008011.1 1160754 1161272 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1160754..1161272) Lawsonia intracellularis PHE/MN1-00 4059882 YP_595307.1 CDS rplA NC_008011.1 1161433 1162140 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1161433..1162140) Lawsonia intracellularis PHE/MN1-00 4059914 YP_595308.1 CDS rplK NC_008011.1 1162245 1162667 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1162245..1162667) Lawsonia intracellularis PHE/MN1-00 4059883 YP_595309.1 CDS nusG NC_008011.1 1162747 1163331 R transcription antiterminator complement(1162747..1163331) Lawsonia intracellularis PHE/MN1-00 4060070 YP_595310.1 CDS tufA NC_008011.1 1163863 1165056 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1163863..1165056) Lawsonia intracellularis PHE/MN1-00 4059507 YP_595311.1 CDS pqqL NC_008011.1 1165638 1168367 R Zn-dependent peptidase complement(1165638..1168367) Lawsonia intracellularis PHE/MN1-00 4059977 YP_595312.1 CDS thiC NC_008011.1 1168519 1169796 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 1168519..1169796 Lawsonia intracellularis PHE/MN1-00 4059816 YP_595313.1 CDS purF NC_008011.1 1169954 1171351 R glutamine phosphoribosylpyrophosphate amidotransferase complement(1169954..1171351) Lawsonia intracellularis PHE/MN1-00 4059993 YP_595314.1 CDS carB NC_008011.1 1171427 1174657 R carbamoylphosphate synthase large subunit (split gene in MJ) complement(1171427..1174657) Lawsonia intracellularis PHE/MN1-00 4060403 YP_595315.1 CDS yqiE NC_008011.1 1174801 1175283 D ADP-ribose pyrophosphatase 1174801..1175283 Lawsonia intracellularis PHE/MN1-00 4059536 YP_595316.1 CDS corC NC_008011.1 1175531 1176382 D Mg2+/Co2+ transporter 1175531..1176382 Lawsonia intracellularis PHE/MN1-00 4060436 YP_595317.1 CDS rpsL NC_008011.1 1176552 1176923 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1176552..1176923 Lawsonia intracellularis PHE/MN1-00 4059854 YP_595318.1 CDS rpsG NC_008011.1 1177061 1177531 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1177061..1177531 Lawsonia intracellularis PHE/MN1-00 4059850 YP_595319.1 CDS fusA NC_008011.1 1177547 1179622 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1177547..1179622 Lawsonia intracellularis PHE/MN1-00 4060313 YP_595320.1 CDS LI0945 NC_008011.1 1179650 1180744 R dienelactone hydrolase complement(1179650..1180744) Lawsonia intracellularis PHE/MN1-00 4059439 YP_595321.1 CDS gidA NC_008011.1 1181886 1183754 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1181886..1183754 Lawsonia intracellularis PHE/MN1-00 4060323 YP_595322.1 CDS LI0947 NC_008011.1 1184004 1184525 D cell wall-associated hydrolases (invasion-associated proteins) 1184004..1184525 Lawsonia intracellularis PHE/MN1-00 4059440 YP_595323.1 CDS LI0948 NC_008011.1 1184566 1185660 R glycosyltransferase complement(1184566..1185660) Lawsonia intracellularis PHE/MN1-00 4059441 YP_595324.1 CDS LI0949 NC_008011.1 1185825 1186151 R hypothetical protein complement(1185825..1186151) Lawsonia intracellularis PHE/MN1-00 4059442 YP_595325.1 CDS LI0950 NC_008011.1 1186164 1187114 R branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase complement(1186164..1187114) Lawsonia intracellularis PHE/MN1-00 4059443 YP_595326.1 CDS asd NC_008011.1 1187315 1188358 R aspartate-semialdehyde dehydrogenase complement(1187315..1188358) Lawsonia intracellularis PHE/MN1-00 4059384 YP_595327.1 CDS LI0952 NC_008011.1 1189061 1189645 R hypothetical protein complement(1189061..1189645) Lawsonia intracellularis PHE/MN1-00 4059444 YP_595328.1 CDS ccmC NC_008011.1 1189772 1190455 R ABC-type transport system involved in cytochrome c biogenesis, permease component complement(1189772..1190455) Lawsonia intracellularis PHE/MN1-00 4060411 YP_595329.1 CDS LI0954 NC_008011.1 1190503 1191180 R ABC-type transport system involved in cytochrome c biogenesis, permease component complement(1190503..1191180) Lawsonia intracellularis PHE/MN1-00 4059445 YP_595330.1 CDS ccmA/ccmB NC_008011.1 1191225 1191860 R ABC-type multidrug transport system, ATPase component complement(1191225..1191860) Lawsonia intracellularis PHE/MN1-00 4060410 YP_595331.1 CDS ccmF NC_008011.1 1191823 1193829 R cytochrome c biogenesis factor complement(1191823..1193829) Lawsonia intracellularis PHE/MN1-00 4060412 YP_595332.1 CDS b2503 NC_008011.1 1193968 1194384 R hypothetical protein complement(1193968..1194384) Lawsonia intracellularis PHE/MN1-00 4060392 YP_595333.1 CDS yhdP NC_008011.1 1194473 1195519 R hemolysin-like protein complement(1194473..1195519) Lawsonia intracellularis PHE/MN1-00 4059531 YP_595334.1 CDS rpsJ NC_008011.1 1196267 1196584 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1196267..1196584 Lawsonia intracellularis PHE/MN1-00 4059852 YP_595335.1 CDS rplC NC_008011.1 1196606 1197238 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1196606..1197238 Lawsonia intracellularis PHE/MN1-00 4059877 YP_595336.1 CDS rplD NC_008011.1 1197254 1197874 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1197254..1197874 Lawsonia intracellularis PHE/MN1-00 4059878 YP_595337.1 CDS rplW NC_008011.1 1197889 1198176 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1197889..1198176 Lawsonia intracellularis PHE/MN1-00 4059838 YP_595338.1 CDS rplB NC_008011.1 1198179 1199009 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1198179..1199009 Lawsonia intracellularis PHE/MN1-00 4059876 YP_595339.1 CDS rpsS NC_008011.1 1199018 1199299 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1199018..1199299 Lawsonia intracellularis PHE/MN1-00 4059624 YP_595340.1 CDS rplV NC_008011.1 1199312 1199650 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1199312..1199650 Lawsonia intracellularis PHE/MN1-00 4059895 YP_595341.1 CDS rpsC NC_008011.1 1199654 1200295 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1199654..1200295 Lawsonia intracellularis PHE/MN1-00 4059847 YP_595342.1 CDS rplP NC_008011.1 1200295 1200708 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1200295..1200708 Lawsonia intracellularis PHE/MN1-00 4059888 YP_003856778.1 CDS LI_1205 NC_008011.1 1200708 1200893 D 50S ribosomal protein L29 1200708..1200893 Lawsonia intracellularis PHE/MN1-00 9711830 YP_595343.1 CDS rpsQ NC_008011.1 1200896 1201162 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1200896..1201162 Lawsonia intracellularis PHE/MN1-00 4059856 YP_595344.1 CDS rplN NC_008011.1 1201178 1201546 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1201178..1201546 Lawsonia intracellularis PHE/MN1-00 4059886 YP_595345.1 CDS rplX NC_008011.1 1201555 1201875 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1201555..1201875 Lawsonia intracellularis PHE/MN1-00 4059839 YP_595346.1 CDS rplE NC_008011.1 1201885 1202424 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1201885..1202424 Lawsonia intracellularis PHE/MN1-00 4059879 YP_595347.1 CDS rpsH NC_008011.1 1202656 1203036 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1202656..1203036 Lawsonia intracellularis PHE/MN1-00 4059851 YP_595348.1 CDS rplF NC_008011.1 1203044 1203589 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1203044..1203589 Lawsonia intracellularis PHE/MN1-00 4059880 YP_595349.1 CDS rplR NC_008011.1 1203602 1203964 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1203602..1203964 Lawsonia intracellularis PHE/MN1-00 4059890 YP_595350.1 CDS rpsE NC_008011.1 1203989 1204480 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1203989..1204480 Lawsonia intracellularis PHE/MN1-00 4059849 YP_595351.1 CDS rplO NC_008011.1 1204661 1205110 D late assembly protein; 50S ribosomal protein L15 1204661..1205110 Lawsonia intracellularis PHE/MN1-00 4059887 YP_595352.1 CDS secY NC_008011.1 1205122 1206429 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1205122..1206429 Lawsonia intracellularis PHE/MN1-00 4059639 YP_595353.1 CDS map NC_008011.1 1206433 1207203 D methionine aminopeptidase 1206433..1207203 Lawsonia intracellularis PHE/MN1-00 4060145 YP_595354.1 CDS rpsM NC_008011.1 1207425 1207793 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1207425..1207793 Lawsonia intracellularis PHE/MN1-00 4059855 YP_595355.1 CDS rpsK NC_008011.1 1207850 1208239 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1207850..1208239 Lawsonia intracellularis PHE/MN1-00 4059853 YP_595356.1 CDS rpsD NC_008011.1 1208262 1208888 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1208262..1208888 Lawsonia intracellularis PHE/MN1-00 4059848 YP_595357.1 CDS rpoA NC_008011.1 1208901 1209944 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1208901..1209944 Lawsonia intracellularis PHE/MN1-00 4059841 YP_595358.1 CDS rplQ NC_008011.1 1209934 1210314 D ribosomal protein L17 1209934..1210314 Lawsonia intracellularis PHE/MN1-00 4059889 YP_595359.1 CDS xanB NC_008011.1 1210609 1212024 D phosphomannose isomerase/GDP-mannose pyrophosphorylase 1210609..1212024 Lawsonia intracellularis PHE/MN1-00 4059613 YP_595360.1 CDS vc0389 NC_008011.1 1212317 1213618 D Na+/H+ antiporter 1212317..1213618 Lawsonia intracellularis PHE/MN1-00 4059611 YP_595361.1 CDS hisS NC_008011.1 1213908 1215167 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1213908..1215167 Lawsonia intracellularis PHE/MN1-00 4059686 YP_595362.1 CDS aspS NC_008011.1 1215195 1216994 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1215195..1216994 Lawsonia intracellularis PHE/MN1-00 4059388 YP_595363.1 CDS dppF NC_008011.1 1217085 1218077 D oligopeptide ABC transporter ATP-binding protein 1217085..1218077 Lawsonia intracellularis PHE/MN1-00 4060383 YP_595364.1 CDS LI0989 NC_008011.1 1218216 1218980 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1218216..1218980 Lawsonia intracellularis PHE/MN1-00 4059446 YP_595365.1 CDS carA NC_008011.1 1218980 1220110 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1218980..1220110 Lawsonia intracellularis PHE/MN1-00 4060402 YP_595366.1 CDS LI0991 NC_008011.1 1220290 1221117 D GluNAc transferase 1220290..1221117 Lawsonia intracellularis PHE/MN1-00 4059447 YP_595367.1 CDS LI0992 NC_008011.1 1221162 1221821 R hypothetical protein complement(1221162..1221821) Lawsonia intracellularis PHE/MN1-00 4059448 YP_595368.1 CDS acrA NC_008011.1 1222274 1223455 D multidrug efflux membrane permease 1222274..1223455 Lawsonia intracellularis PHE/MN1-00 4060341 YP_595369.1 CDS acrB NC_008011.1 1223455 1226604 D acriflavin resistance protein D 1223455..1226604 Lawsonia intracellularis PHE/MN1-00 4060342 YP_595370.1 CDS oprM NC_008011.1 1226608 1227987 D outer membrane efflux protein 1226608..1227987 Lawsonia intracellularis PHE/MN1-00 4060017 YP_595371.1 CDS LI0996 NC_008011.1 1228358 1228783 D hypothetical protein 1228358..1228783 Lawsonia intracellularis PHE/MN1-00 4059449 YP_595372.1 CDS purB NC_008011.1 1228824 1230155 D adenylosuccinate lyase 1228824..1230155 Lawsonia intracellularis PHE/MN1-00 4059990 YP_595373.1 CDS pyrE NC_008011.1 1230186 1230749 D orotate phosphoribosyltransferase 1230186..1230749 Lawsonia intracellularis PHE/MN1-00 4059968 YP_595374.1 CDS LI0999 NC_008011.1 1231102 1232007 D hypothetical protein 1231102..1232007 Lawsonia intracellularis PHE/MN1-00 4059450 YP_595375.1 CDS LI1000 NC_008011.1 1232004 1232939 D hypothetical protein 1232004..1232939 Lawsonia intracellularis PHE/MN1-00 4059451 YP_595376.1 CDS napC NC_008011.1 1233552 1234028 D cytochrome c nitrite reductase small subunit 1233552..1234028 Lawsonia intracellularis PHE/MN1-00 4060053 YP_595377.1 CDS nrfA NC_008011.1 1234021 1235574 D chain A, cytochrome C nitrite reductase 1234021..1235574 Lawsonia intracellularis PHE/MN1-00 4060064 YP_595378.1 CDS lysC NC_008011.1 1235666 1236898 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(1235666..1236898) Lawsonia intracellularis PHE/MN1-00 4060139 YP_595379.1 CDS LI1004 NC_008011.1 1236903 1237505 R ATPase or kinase complement(1236903..1237505) Lawsonia intracellularis PHE/MN1-00 4059452 YP_595380.1 CDS truB NC_008011.1 1237651 1238547 D pseudouridine synthase 1237651..1238547 Lawsonia intracellularis PHE/MN1-00 4059501 YP_003856779.1 CDS LI_1210 NC_008011.1 1238578 1238847 D 30S ribosomal protein S15 1238578..1238847 Lawsonia intracellularis PHE/MN1-00 9711829 YP_595381.1 CDS pnpA NC_008011.1 1239053 1241263 D polynucleotide phosphorylase 1239053..1241263 Lawsonia intracellularis PHE/MN1-00 4060001 YP_595382.1 CDS gatB NC_008011.1 1241379 1242812 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(1241379..1242812) Lawsonia intracellularis PHE/MN1-00 4060320 YP_595383.1 CDS LI1008 NC_008011.1 1242831 1243469 R hypothetical protein complement(1242831..1243469) Lawsonia intracellularis PHE/MN1-00 4059453 YP_595384.1 CDS yfjB NC_008011.1 1244106 1244963 R sugar kinase complement(1244106..1244963) Lawsonia intracellularis PHE/MN1-00 4059621 YP_595385.1 CDS gmhA NC_008011.1 1245221 1245856 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 1245221..1245856 Lawsonia intracellularis PHE/MN1-00 4060228 YP_595386.1 CDS hemC NC_008011.1 1246200 1247129 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1246200..1247129 Lawsonia intracellularis PHE/MN1-00 4060262 YP_595387.1 CDS lon NC_008011.1 1247217 1249670 D ATP-dependent protease 1247217..1249670 Lawsonia intracellularis PHE/MN1-00 4060131 YP_595388.1 CDS nar NC_008011.1 1249691 1250893 R major facilitator superfamily permease complement(1249691..1250893) Lawsonia intracellularis PHE/MN1-00 4060054 YP_595389.1 CDS LI1014 NC_008011.1 1251229 1251711 D hypothetical protein 1251229..1251711 Lawsonia intracellularis PHE/MN1-00 4059454 YP_595390.1 CDS gmpA NC_008011.1 1251726 1253258 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1251726..1253258 Lawsonia intracellularis PHE/MN1-00 4060250 YP_595391.1 CDS LI1016 NC_008011.1 1253603 1253965 R hypothetical protein complement(1253603..1253965) Lawsonia intracellularis PHE/MN1-00 4059279 YP_595392.1 CDS LI1017 NC_008011.1 1253967 1254572 R hypothetical protein complement(1253967..1254572) Lawsonia intracellularis PHE/MN1-00 4059280 YP_595393.1 CDS rfaQ NC_008011.1 1254631 1256223 R ADP-heptose:LPS heptosyltransferase complement(1254631..1256223) Lawsonia intracellularis PHE/MN1-00 4059950 YP_595394.1 CDS lpxA NC_008011.1 1256500 1257321 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1256500..1257321) Lawsonia intracellularis PHE/MN1-00 4060132 YP_595395.1 CDS fabZ NC_008011.1 1257321 1257782 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1257321..1257782) Lawsonia intracellularis PHE/MN1-00 4059307 YP_595396.1 CDS lpxD NC_008011.1 1257792 1258817 R UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(1257792..1258817) Lawsonia intracellularis PHE/MN1-00 4060135 YP_595397.1 CDS LI1022 NC_008011.1 1258821 1259381 R Outer membrane protein complement(1258821..1259381) Lawsonia intracellularis PHE/MN1-00 4059281 YP_595398.1 CDS amiA NC_008011.1 1259526 1261328 R N-acetylmuramoyl-L-alanine amidase complement(1259526..1261328) Lawsonia intracellularis PHE/MN1-00 4060346 YP_595399.1 CDS LI1024 NC_008011.1 1261471 1264125 R Outer membrane protein/protective antigen OMA87 complement(1261471..1264125) Lawsonia intracellularis PHE/MN1-00 4059282 YP_595400.1 CDS lolD NC_008011.1 1264118 1264825 R ABC-type transport system, involved in lipoprotein release, permease component complement(1264118..1264825) Lawsonia intracellularis PHE/MN1-00 4059660 YP_595401.1 CDS lolC NC_008011.1 1264828 1266111 R ABC-type transport system, involved in lipoprotein release, permease component complement(1264828..1266111) Lawsonia intracellularis PHE/MN1-00 4059659 YP_595402.1 CDS lysU NC_008011.1 1266111 1267484 R lysyl-tRNA synthetase (class II) complement(1266111..1267484) Lawsonia intracellularis PHE/MN1-00 4060140 YP_595403.1 CDS LI1028 NC_008011.1 1268376 1269200 D phosphate-binding protein 1268376..1269200 Lawsonia intracellularis PHE/MN1-00 4059283 YP_595404.1 CDS pstC NC_008011.1 1269253 1270083 D phosphate transporter permease PstC 1269253..1270083 Lawsonia intracellularis PHE/MN1-00 4059987 YP_595405.1 CDS pstA NC_008011.1 1270080 1270970 D phosphate ABC transporter, permease 1270080..1270970 Lawsonia intracellularis PHE/MN1-00 4059985 YP_595406.1 CDS pstB NC_008011.1 1270961 1271734 D phosphate ABC transporter ATP-binding protein 1270961..1271734 Lawsonia intracellularis PHE/MN1-00 4059986 YP_595407.1 CDS LI1032 NC_008011.1 1271838 1272293 R hypothetical protein complement(1271838..1272293) Lawsonia intracellularis PHE/MN1-00 4059284 YP_595408.1 CDS LI1033 NC_008011.1 1272481 1273890 R hypothetical protein complement(1272481..1273890) Lawsonia intracellularis PHE/MN1-00 4059285 YP_595409.1 CDS LI1034 NC_008011.1 1274250 1275641 R hypothetical protein complement(1274250..1275641) Lawsonia intracellularis PHE/MN1-00 4059286 YP_595410.1 CDS LI1035 NC_008011.1 1276286 >1277317 R hypothetical protein complement(1276286..>1277317) Lawsonia intracellularis PHE/MN1-00 4059287 YP_595411.1 CDS LI1036 NC_008011.1 1277447 1278403 R hypothetical protein complement(1277447..1278403) Lawsonia intracellularis PHE/MN1-00 4059288 YP_595412.1 CDS LI1037 NC_008011.1 1278568 1279566 R hypothetical protein complement(1278568..1279566) Lawsonia intracellularis PHE/MN1-00 4059289 YP_595413.1 CDS LI1038 NC_008011.1 1279875 1280561 R hypothetical protein complement(1279875..1280561) Lawsonia intracellularis PHE/MN1-00 4059290 YP_595414.1 CDS LI1039 NC_008011.1 1281061 1282206 R hypothetical protein complement(1281061..1282206) Lawsonia intracellularis PHE/MN1-00 4059291 YP_595415.1 CDS LI1040 NC_008011.1 1282447 1283466 R hypothetical protein complement(1282447..1283466) Lawsonia intracellularis PHE/MN1-00 4059292 YP_595416.1 CDS LI1041 NC_008011.1 1283628 1284554 R hypothetical protein complement(1283628..1284554) Lawsonia intracellularis PHE/MN1-00 4059293 YP_595417.1 CDS LI1042 NC_008011.1 1285000 1286004 R hypothetical protein complement(1285000..1286004) Lawsonia intracellularis PHE/MN1-00 4059294 YP_595418.1 CDS hprA NC_008011.1 1286368 1287339 R lactate dehydrogenase and related dehydrogenases complement(1286368..1287339) Lawsonia intracellularis PHE/MN1-00 4059688 YP_595419.1 CDS LI1044 NC_008011.1 1287421 1288035 R hypothetical protein complement(1287421..1288035) Lawsonia intracellularis PHE/MN1-00 4059295 YP_595420.1 CDS pqiB NC_008011.1 1288038 1288997 R paraquat-inducible protein B complement(1288038..1288997) Lawsonia intracellularis PHE/MN1-00 4059976 YP_595421.1 CDS LI1046 NC_008011.1 1288994 1289782 R ABC-type transport system involved in resistance to organic solvents, ATPase component complement(1288994..1289782) Lawsonia intracellularis PHE/MN1-00 4059296 YP_595422.1 CDS ttg2B NC_008011.1 1289790 1290950 R ABC-type transport system involved in resistance to organic solvents, permease component complement(1289790..1290950) Lawsonia intracellularis PHE/MN1-00 4059506 YP_595423.1 CDS grpE NC_008011.1 1291103 1291672 R molecular chaperone GrpE (heat shock protein) complement(1291103..1291672) Lawsonia intracellularis PHE/MN1-00 4060254 YP_595424.1 CDS LI1049 NC_008011.1 1292388 1293122 D hypothetical protein 1292388..1293122 Lawsonia intracellularis PHE/MN1-00 4059297 YP_595425.1 CDS LI1050 NC_008011.1 1293526 1294392 D metal-dependent phosphoesterase 1293526..1294392 Lawsonia intracellularis PHE/MN1-00 4060446 YP_595426.1 CDS ileS NC_008011.1 1294652 1297465 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1294652..1297465 Lawsonia intracellularis PHE/MN1-00 4059667 YP_595427.1 CDS lsp NC_008011.1 1297490 1297984 D lipoprotein signal peptidase 1297490..1297984 Lawsonia intracellularis PHE/MN1-00 4060137 YP_595428.1 CDS LI1053 NC_008011.1 1298127 1299044 D hypothetical protein 1298127..1299044 Lawsonia intracellularis PHE/MN1-00 4060447 YP_595429.1 CDS cheZ NC_008011.1 1299149 1299931 D chemotaxis protein 1299149..1299931 Lawsonia intracellularis PHE/MN1-00 4060424 YP_595430.1 CDS lpxB NC_008011.1 1300313 1301428 D Lipid A disaccharide synthetase 1300313..1301428 Lawsonia intracellularis PHE/MN1-00 4060133 YP_595431.1 CDS LI1056 NC_008011.1 1301682 1302152 D hypothetical protein 1301682..1302152 Lawsonia intracellularis PHE/MN1-00 4060448 YP_595432.1 CDS atpA NC_008011.1 1302188 1302889 D F0F1-type ATP synthase, subunit a 1302188..1302889 Lawsonia intracellularis PHE/MN1-00 4059392 YP_595433.1 CDS atpC NC_008011.1 1302949 1303296 D F0F1-type ATP synthase, subunit c 1302949..1303296 Lawsonia intracellularis PHE/MN1-00 4060388 YP_595434.1 CDS LI1059 NC_008011.1 1303342 1303977 D modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1303342..1303977 Lawsonia intracellularis PHE/MN1-00 4060449 YP_595435.1 CDS LI1060 NC_008011.1 1304124 1304564 D flagellar biosynthesis chaperone 1304124..1304564 Lawsonia intracellularis PHE/MN1-00 4060450 YP_595436.1 CDS LI1061 NC_008011.1 1304581 1305333 D hypothetical protein 1304581..1305333 Lawsonia intracellularis PHE/MN1-00 4060451 YP_595437.1 CDS truA NC_008011.1 1305357 1306130 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1305357..1306130 Lawsonia intracellularis PHE/MN1-00 4059500 YP_595438.1 CDS LI1063 NC_008011.1 1306382 1306804 D hypothetical protein 1306382..1306804 Lawsonia intracellularis PHE/MN1-00 4060452 YP_595439.1 CDS fdhF NC_008011.1 1307072 1307548 D Fe-S-cluster-containing hydrogenase components 1 1307072..1307548 Lawsonia intracellularis PHE/MN1-00 4059310 YP_595440.1 CDS rfbD NC_008011.1 1307621 1308496 R dTDP-4-dehydrorhamnose reductase complement(1307621..1308496) Lawsonia intracellularis PHE/MN1-00 4059953 YP_595441.1 CDS rfbB NC_008011.1 1308493 1309512 R dTDP-D-glucose 4,6-dehydratase complement(1308493..1309512) Lawsonia intracellularis PHE/MN1-00 4059952 YP_595442.1 CDS LI1067 NC_008011.1 1309801 1310592 D cobalamin biosynthesis protein CbiK, Co2+ chelatase 1309801..1310592 Lawsonia intracellularis PHE/MN1-00 4060453 YP_595443.1 CDS LI1068 NC_008011.1 1310656 1311624 D hypothetical protein 1310656..1311624 Lawsonia intracellularis PHE/MN1-00 4060454 YP_595444.1 CDS rnpA NC_008011.1 1312240 1312479 D RNase P protein component 1312240..1312479 Lawsonia intracellularis PHE/MN1-00 4059910 YP_595445.1 CDS yidC NC_008011.1 1312833 1314431 D preprotein translocase subunit YidC 1312833..1314431 Lawsonia intracellularis PHE/MN1-00 4059533 YP_595446.1 CDS jag NC_008011.1 1314455 1315468 D RNA-binding protein 1314455..1315468 Lawsonia intracellularis PHE/MN1-00 4059672 YP_595447.1 CDS trmE NC_008011.1 1315534 1316913 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1315534..1316913 Lawsonia intracellularis PHE/MN1-00 4059815 YP_595448.1 CDS rncS NC_008011.1 1316917 1317513 D ribonuclease D 1316917..1317513 Lawsonia intracellularis PHE/MN1-00 4059907 YP_595449.1 CDS LI1074 NC_008011.1 1317595 1320534 D endonuclease 1317595..1320534 Lawsonia intracellularis PHE/MN1-00 4060455 YP_595450.1 CDS ncd2 NC_008011.1 1320591 1321721 D dioxygenases related to 2-nitropropane dioxygenase 1320591..1321721 Lawsonia intracellularis PHE/MN1-00 4060055 YP_595451.1 CDS glk NC_008011.1 1321808 1322791 R glucokinase complement(1321808..1322791) Lawsonia intracellularis PHE/MN1-00 4060326 YP_595452.1 CDS LI1077 NC_008011.1 1322933 1323712 R hypothetical protein complement(1322933..1323712) Lawsonia intracellularis PHE/MN1-00 4060456 YP_595453.1 CDS HydH NC_008011.1 1324889 1326631 D Signal transduction histidine kinase 1324889..1326631 Lawsonia intracellularis PHE/MN1-00 4059699 YP_595454.1 CDS hydG NC_008011.1 1326651 1328066 D response regulator 1326651..1328066 Lawsonia intracellularis PHE/MN1-00 4059698 YP_595455.1 CDS LI1080 NC_008011.1 1328199 1328615 D hypothetical protein 1328199..1328615 Lawsonia intracellularis PHE/MN1-00 4060457 YP_595456.1 CDS oppD NC_008011.1 1328645 1329628 R oligopeptide ABC transporter complement(1328645..1329628) Lawsonia intracellularis PHE/MN1-00 4060016 YP_595457.1 CDS feoA NC_008011.1 1330153 1330491 D Fe2+ transport system protein A 1330153..1330491 Lawsonia intracellularis PHE/MN1-00 4059311 YP_595458.1 CDS feoB NC_008011.1 1330619 1332820 D Fe2+ transport system protein B 1330619..1332820 Lawsonia intracellularis PHE/MN1-00 4059312 YP_595459.1 CDS glpC NC_008011.1 1332824 1334038 R anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C complement(1332824..1334038) Lawsonia intracellularis PHE/MN1-00 4060458 YP_595460.1 CDS LI1085 NC_008011.1 1334050 1335303 R sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(1334050..1335303) Lawsonia intracellularis PHE/MN1-00 4060459 YP_595461.1 CDS glpA NC_008011.1 1335296 1336924 R anaerobic glycerol-3-phosphate dehydrogenase subunit A complement(1335296..1336924) Lawsonia intracellularis PHE/MN1-00 4060219 YP_595462.1 CDS LI1087 NC_008011.1 1337223 1337819 R hypothetical protein complement(1337223..1337819) Lawsonia intracellularis PHE/MN1-00 4060460 YP_595463.1 CDS LI1088 NC_008011.1 1337816 1338124 R hypothetical protein complement(1337816..1338124) Lawsonia intracellularis PHE/MN1-00 4060461 YP_595464.1 CDS LI1089 NC_008011.1 1338433 1339086 D methyltransferase 1338433..1339086 Lawsonia intracellularis PHE/MN1-00 4060462 YP_595465.1 CDS LI1090 NC_008011.1 1339149 1339568 D transcription regulator 1339149..1339568 Lawsonia intracellularis PHE/MN1-00 4060463 YP_595466.1 CDS LI1091 NC_008011.1 1339592 1340368 D similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase 1339592..1340368 Lawsonia intracellularis PHE/MN1-00 4060464 YP_595467.1 CDS LI1092 NC_008011.1 1340557 1341606 D response regulator 1340557..1341606 Lawsonia intracellularis PHE/MN1-00 4060465 YP_595468.1 CDS LI1093 NC_008011.1 1341663 1344893 D Outer membrane protein and related peptidoglycan-associated (lipo)proteins 1341663..1344893 Lawsonia intracellularis PHE/MN1-00 4060349 YP_595469.1 CDS LI1094 NC_008011.1 1344921 1345964 R HD-GYP domain-containing protein complement(1344921..1345964) Lawsonia intracellularis PHE/MN1-00 4060350 YP_595470.1 CDS pykF NC_008011.1 1345968 1347383 R pyruvate kinase complement(1345968..1347383) Lawsonia intracellularis PHE/MN1-00 4059963 YP_595471.1 CDS mraZ NC_008011.1 1347589 1348038 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1347589..1348038 Lawsonia intracellularis PHE/MN1-00 4060128 YP_595472.1 CDS mraW NC_008011.1 1348109 1349047 D S-adenosyl-methyltransferase MraW 1348109..1349047 Lawsonia intracellularis PHE/MN1-00 4060351 YP_595473.1 CDS ftsI NC_008011.1 1349553 1351634 D cell division protein FtsI/penicillin-binding protein 2 1349553..1351634 Lawsonia intracellularis PHE/MN1-00 4059756 YP_595474.1 CDS murE NC_008011.1 1351636 1353084 D UDP-N-acetylmuramyl tripeptide synthase 1351636..1353084 Lawsonia intracellularis PHE/MN1-00 4060077 YP_595475.1 CDS murF NC_008011.1 1353075 1354469 D UDP-N-acetylmuramyl pentapeptide synthase 1353075..1354469 Lawsonia intracellularis PHE/MN1-00 4060078 YP_595476.1 CDS mraY NC_008011.1 1354469 1355545 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1354469..1355545 Lawsonia intracellularis PHE/MN1-00 4060127 YP_595477.1 CDS murD NC_008011.1 1355559 1356881 D UDP-N-acetylmuramoylalanine-D-glutamate ligase 1355559..1356881 Lawsonia intracellularis PHE/MN1-00 4060076 YP_595478.1 CDS spoVE NC_008011.1 1356868 1358016 D cell division membrane protein 1356868..1358016 Lawsonia intracellularis PHE/MN1-00 4059807 YP_595479.1 CDS murG NC_008011.1 1358021 1359112 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1358021..1359112 Lawsonia intracellularis PHE/MN1-00 4060079 YP_595480.1 CDS murC NC_008011.1 1359109 1360470 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1359109..1360470 Lawsonia intracellularis PHE/MN1-00 4060075 YP_595481.1 CDS LI1106 NC_008011.1 1360502 1361392 D UDP-N-acetylmuramate dehydrogenase 1360502..1361392 Lawsonia intracellularis PHE/MN1-00 4060352 YP_595482.1 CDS ftsQ NC_008011.1 1361386 1362213 D cell division septal protein 1361386..1362213 Lawsonia intracellularis PHE/MN1-00 4059758 YP_595483.1 CDS ftsA NC_008011.1 1362407 1363639 D cell division protein FtsA 1362407..1363639 Lawsonia intracellularis PHE/MN1-00 4059754 YP_595484.1 CDS ftsZ NC_008011.1 1363691 1365073 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1363691..1365073 Lawsonia intracellularis PHE/MN1-00 4059759 YP_595485.1 CDS LI1110 NC_008011.1 1365182 1365661 D hypothetical protein 1365182..1365661 Lawsonia intracellularis PHE/MN1-00 4060353 YP_595486.1 CDS LI1111 NC_008011.1 1365658 1366440 R amidophosphoribosyltransferase complement(1365658..1366440) Lawsonia intracellularis PHE/MN1-00 4060354 YP_595487.1 CDS LI1112 NC_008011.1 1366446 1367042 R multimeric flavodoxin WrbA complement(1366446..1367042) Lawsonia intracellularis PHE/MN1-00 4060355 YP_595488.1 CDS argF NC_008011.1 1367118 1368020 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase complement(1367118..1368020) Lawsonia intracellularis PHE/MN1-00 4059379 YP_595489.1 CDS LI1114 NC_008011.1 1368164 1370053 R parvulin-like peptidyl-prolyl isomerase complement(1368164..1370053) Lawsonia intracellularis PHE/MN1-00 4060356 YP_595490.1 CDS flbD NC_008011.1 1370349 1371827 R response regulator complement(1370349..1371827) Lawsonia intracellularis PHE/MN1-00 4059313 YP_595491.1 CDS priS NC_008011.1 1372257 1373870 D catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1372257..1373870 Lawsonia intracellularis PHE/MN1-00 4059980 YP_595492.1 CDS cheV NC_008011.1 1374180 1375139 D chemotaxis signal transduction protein 1374180..1375139 Lawsonia intracellularis PHE/MN1-00 4060419 YP_595493.1 CDS LI1118 NC_008011.1 1375188 1375997 D hypothetical protein 1375188..1375997 Lawsonia intracellularis PHE/MN1-00 4060357 YP_595494.1 CDS gapB NC_008011.1 1376132 1377148 R glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase complement(1376132..1377148) Lawsonia intracellularis PHE/MN1-00 4060319 YP_595495.1 CDS proC NC_008011.1 1377471 1378307 R pyrroline-5-carboxylate reductase complement(1377471..1378307) Lawsonia intracellularis PHE/MN1-00 4059981 YP_595496.1 CDS ndk NC_008011.1 1378307 1378723 R nucleoside-diphosphate kinase complement(1378307..1378723) Lawsonia intracellularis PHE/MN1-00 4060056 YP_595497.1 CDS LI1122 NC_008011.1 1378753 1380090 R hypothetical protein complement(1378753..1380090) Lawsonia intracellularis PHE/MN1-00 4060358 YP_595498.1 CDS prc NC_008011.1 1380396 1381724 R periplasmic protease complement(1380396..1381724) Lawsonia intracellularis PHE/MN1-00 4059978 YP_595499.1 CDS nth NC_008011.1 1381792 1382472 R endonuclease III complement(1381792..1382472) Lawsonia intracellularis PHE/MN1-00 4060066 YP_595500.1 CDS copA NC_008011.1 1382916 1385270 R copper-translocating P-type ATPase complement(1382916..1385270) Lawsonia intracellularis PHE/MN1-00 4060434 YP_595501.1 CDS LI1126 NC_008011.1 1385472 1385933 D RNA methyltransferase 1385472..1385933 Lawsonia intracellularis PHE/MN1-00 4060359 YP_595502.1 CDS LI1127 NC_008011.1 1385991 1387358 D Na+-driven multidrug efflux pump 1385991..1387358 Lawsonia intracellularis PHE/MN1-00 4060360 YP_595503.1 CDS LI1128 NC_008011.1 1387436 1388335 D hypothetical protein 1387436..1388335 Lawsonia intracellularis PHE/MN1-00 4060361 YP_595504.1 CDS glnQ NC_008011.1 1388490 1389227 D ABC-type polar amino acid transport system, ATPase component 1388490..1389227 Lawsonia intracellularis PHE/MN1-00 4060216 YP_595505.1 CDS LI1130 NC_008011.1 1389244 1390113 D ribosomal protein L11 methylase 1389244..1390113 Lawsonia intracellularis PHE/MN1-00 4060362 YP_595506.1 CDS secG NC_008011.1 1390148 1390486 R preprotein translocase subunit SecG complement(1390148..1390486) Lawsonia intracellularis PHE/MN1-00 4059638 YP_595507.1 CDS tpiA NC_008011.1 1390582 1391340 R triosephosphate isomerase complement(1390582..1391340) Lawsonia intracellularis PHE/MN1-00 4059831 YP_595508.1 CDS rimJ NC_008011.1 1391360 1391830 R acetyltransferase complement(1391360..1391830) Lawsonia intracellularis PHE/MN1-00 4059901 YP_595509.1 CDS LI1134 NC_008011.1 1391831 1392370 D NTP pyrophosphohydrolases including oxidative damage repair enzymes 1391831..1392370 Lawsonia intracellularis PHE/MN1-00 4060363 YP_595510.1 CDS mreB NC_008011.1 1392420 1393421 R rod shape-determining protein MreB complement(1392420..1393421) Lawsonia intracellularis PHE/MN1-00 4060130 YP_595511.1 CDS LI1136 NC_008011.1 1393424 1394458 R hypothetical protein complement(1393424..1394458) Lawsonia intracellularis PHE/MN1-00 4060364 YP_595512.1 CDS cheB NC_008011.1 1394777 1395850 D chemotaxis response regulator 1394777..1395850 Lawsonia intracellularis PHE/MN1-00 4060416 YP_595513.1 CDS LI1138 NC_008011.1 1395874 1397826 D hypothetical protein 1395874..1397826 Lawsonia intracellularis PHE/MN1-00 4060365 YP_595514.1 CDS cheR NC_008011.1 1397826 1398701 D methylase of chemotaxis methyl-accepting proteins 1397826..1398701 Lawsonia intracellularis PHE/MN1-00 4060417 YP_595515.1 CDS soj NC_008011.1 1398717 1399487 D chromosome partitioning ATPase 1398717..1399487 Lawsonia intracellularis PHE/MN1-00 4059805 YP_595516.1 CDS cheW NC_008011.1 1399691 1400161 D chemotaxis signal transduction protein 1399691..1400161 Lawsonia intracellularis PHE/MN1-00 4060420 YP_595517.1 CDS cheY NC_008011.1 1400172 1400540 D CheY-like receiver 1400172..1400540 Lawsonia intracellularis PHE/MN1-00 4060423 YP_595518.1 CDS cheA_1 NC_008011.1 1400564 1401208 D chemotaxis protein histidine kinase-like kinase 1400564..1401208 Lawsonia intracellularis PHE/MN1-00 4060414 YP_595519.1 CDS cheA_2 NC_008011.1 1401396 1403609 D chemotaxis protein histidine kinase-like kinase 1401396..1403609 Lawsonia intracellularis PHE/MN1-00 4060415 YP_595525.1 CDS LI1150 NC_008011.1 1409027 >1411030 R regulator complement(1409027..>1411030) Lawsonia intracellularis PHE/MN1-00 4059917 YP_595526.1 CDS LI1151 NC_008011.1 1411391 1412671 R transcriptional regulator complement(1411391..1412671) Lawsonia intracellularis PHE/MN1-00 4059918 YP_595527.1 CDS LI1152 NC_008011.1 1412680 1413048 R hypothetical protein complement(1412680..1413048) Lawsonia intracellularis PHE/MN1-00 4059919 YP_595528.1 CDS LI1153 NC_008011.1 1413348 >1414544 R outer protein N complement(1413348..>1414544) Lawsonia intracellularis PHE/MN1-00 4059920 YP_595529.1 CDS LI1154 NC_008011.1 1415356 1416042 D hypothetical protein 1415356..1416042 Lawsonia intracellularis PHE/MN1-00 4059921 YP_595530.1 CDS LI1155 NC_008011.1 1416504 1417094 D hypothetical protein 1416504..1417094 Lawsonia intracellularis PHE/MN1-00 4059922 YP_595531.1 CDS LI1156 NC_008011.1 1418018 1418524 D hypothetical protein 1418018..1418524 Lawsonia intracellularis PHE/MN1-00 4059923 YP_595532.1 CDS LI1157 NC_008011.1 1419132 1419671 D regulatory protein PcrH 1419132..1419671 Lawsonia intracellularis PHE/MN1-00 4059924 YP_595533.1 CDS LI1158 NC_008011.1 1419668 1420858 D hypothetical protein 1419668..1420858 Lawsonia intracellularis PHE/MN1-00 4059925 YP_595534.1 CDS LI1159 NC_008011.1 1420906 1421703 D hypothetical protein 1420906..1421703 Lawsonia intracellularis PHE/MN1-00 4059926 YP_595535.1 CDS YscC NC_008011.1 1422992 1424743 D type III secretion protein YscC 1422992..1424743 Lawsonia intracellularis PHE/MN1-00 4059537 YP_595536.1 CDS LI1161 NC_008011.1 1424743 1426164 D hypothetical protein 1424743..1426164 Lawsonia intracellularis PHE/MN1-00 4059927 YP_595537.1 CDS LI1162 NC_008011.1 1426377 1426856 D hypothetical protein 1426377..1426856 Lawsonia intracellularis PHE/MN1-00 4059928 YP_595538.1 CDS YscJ NC_008011.1 1426865 1427701 D type III secretion protein 1426865..1427701 Lawsonia intracellularis PHE/MN1-00 4059538 YP_595539.1 CDS YscL NC_008011.1 <1427698 1428378 D type III secretion protein <1427698..1428378 Lawsonia intracellularis PHE/MN1-00 4059539 YP_595540.1 CDS LI1165 NC_008011.1 1428350 1429231 D hypothetical protein 1428350..1429231 Lawsonia intracellularis PHE/MN1-00 4059929 YP_595541.1 CDS LI1166 NC_008011.1 1429285 1430391 D translocation protein in type III secretion 1429285..1430391 Lawsonia intracellularis PHE/MN1-00 4059930 YP_595542.1 CDS LI1167 NC_008011.1 1430468 1430806 D anti-anti-sigma factor 1430468..1430806 Lawsonia intracellularis PHE/MN1-00 4059931 YP_595543.1 CDS rsbW NC_008011.1 1430820 1431263 D sigma regulatory factor-histidine kinase 1430820..1431263 Lawsonia intracellularis PHE/MN1-00 4059626 YP_595544.1 CDS LI1169 NC_008011.1 1431313 1432011 D transglycosylase 1431313..1432011 Lawsonia intracellularis PHE/MN1-00 4059932 YP_595545.1 CDS cheW NC_008011.1 1432180 1432665 D chemotaxis signal transduction protein 1432180..1432665 Lawsonia intracellularis PHE/MN1-00 4060421 YP_595546.1 CDS LI1171 NC_008011.1 1432770 1434458 R 5'-nucleotidase complement(1432770..1434458) Lawsonia intracellularis PHE/MN1-00 4059933 YP_595547.1 CDS LI1172 NC_008011.1 1434763 1435746 D hypothetical protein 1434763..1435746 Lawsonia intracellularis PHE/MN1-00 4059934 YP_595548.1 CDS LI1173 NC_008011.1 1435746 1438211 D small-conductance mechanosensitive channel 1435746..1438211 Lawsonia intracellularis PHE/MN1-00 4060330 YP_595549.1 CDS mltC NC_008011.1 1438532 1439695 D membrane-bound lytic murein transglycosylase C (MltC) 1438532..1439695 Lawsonia intracellularis PHE/MN1-00 4060121 YP_595550.1 CDS LI1175 NC_008011.1 1439752 1440264 D hypothetical protein 1439752..1440264 Lawsonia intracellularis PHE/MN1-00 4060331 YP_595551.1 CDS LI1176 NC_008011.1 1440333 1441112 R nitroreductase complement(1440333..1441112) Lawsonia intracellularis PHE/MN1-00 4060332 YP_595552.1 CDS LI1177 NC_008011.1 1441109 1443982 R excinuclease ABC, A subunit complement(1441109..1443982) Lawsonia intracellularis PHE/MN1-00 4060333 YP_595553.1 CDS LI1178 NC_008011.1 1444320 1445030 R ABC-type cobalt transport system, permease component CbiQ and related transporters complement(1444320..1445030) Lawsonia intracellularis PHE/MN1-00 4060334 YP_595554.1 CDS cbiO NC_008011.1 1445008 1445748 R ABC-type cobalt transport system, ATPase component complement(1445008..1445748) Lawsonia intracellularis PHE/MN1-00 4060407 YP_595555.1 CDS bioY NC_008011.1 1445735 1446292 R hypothetical protein complement(1445735..1446292) Lawsonia intracellularis PHE/MN1-00 4060400 YP_595556.1 CDS alaS NC_008011.1 1446330 1448984 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1446330..1448984) Lawsonia intracellularis PHE/MN1-00 4060344 YP_595557.1 CDS recA NC_008011.1 1449016 1450083 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1449016..1450083) Lawsonia intracellularis PHE/MN1-00 4059938 YP_595558.1 CDS metG NC_008011.1 1450184 1452139 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1450184..1452139) Lawsonia intracellularis PHE/MN1-00 4060114 YP_595559.1 CDS LI1184 NC_008011.1 1452273 1453223 R uncharacterized homolog of PSP1 complement(1452273..1453223) Lawsonia intracellularis PHE/MN1-00 4060335 YP_595560.1 CDS LI1185 NC_008011.1 1454268 1454885 R hypothetical protein complement(1454268..1454885) Lawsonia intracellularis PHE/MN1-00 4060336 YP_595561.1 CDS ruvA NC_008011.1 1455153 1455752 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1455153..1455752 Lawsonia intracellularis PHE/MN1-00 4059629 YP_595562.1 CDS ruvB NC_008011.1 1455725 1456750 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1455725..1456750 Lawsonia intracellularis PHE/MN1-00 4059630 YP_595563.1 CDS thyX NC_008011.1 1456767 1457489 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 1456767..1457489 Lawsonia intracellularis PHE/MN1-00 4059824 YP_595564.1 CDS LIA001 NC_008012.1 280 1359 D integrase 280..1359 Lawsonia intracellularis PHE/MN1-00 4073387 YP_595565.1 CDS LIA002 NC_008012.1 1564 1920 R hypothetical protein complement(1564..1920) Lawsonia intracellularis PHE/MN1-00 4073388 YP_595566.1 CDS LIA003 NC_008012.1 1914 2264 R hypothetical protein complement(1914..2264) Lawsonia intracellularis PHE/MN1-00 4073389 YP_595567.1 CDS LIA004 NC_008012.1 2560 2889 D hypothetical protein 2560..2889 Lawsonia intracellularis PHE/MN1-00 4073390 YP_595568.1 CDS LIA005 NC_008012.1 3335 5296 R hypothetical protein complement(3335..5296) Lawsonia intracellularis PHE/MN1-00 4073391 YP_595569.1 CDS LIA006 NC_008012.1 5817 6476 R hypothetical protein complement(5817..6476) Lawsonia intracellularis PHE/MN1-00 4073392 YP_595570.1 CDS LIA007 NC_008012.1 <6841 7245 R hypothetical protein complement(<6841..7245) Lawsonia intracellularis PHE/MN1-00 4073393 YP_595571.1 CDS mvaK1 NC_008012.1 7296 8276 R putative galactokinase/mevalonate kinase complement(7296..8276) Lawsonia intracellularis PHE/MN1-00 4073396 YP_595572.1 CDS LIA009 NC_008012.1 8304 9590 R hypothetical protein complement(8304..9590) Lawsonia intracellularis PHE/MN1-00 4073394 YP_595573.1 CDS LIA010 NC_008012.1 9603 10622 R Cps2K complement(9603..10622) Lawsonia intracellularis PHE/MN1-00 4073397 YP_595574.1 CDS LIA011 NC_008012.1 10908 11360 R S-adenosylmethionine-dependent methyltransferase complement(10908..11360) Lawsonia intracellularis PHE/MN1-00 4073398 YP_595575.1 CDS LIA012 NC_008012.1 11381 12091 R hypothetical protein complement(11381..12091) Lawsonia intracellularis PHE/MN1-00 4073399 YP_595576.1 CDS LIA013 NC_008012.1 12124 12882 R biotin synthesis protein BioC complement(12124..12882) Lawsonia intracellularis PHE/MN1-00 4073400 YP_595577.1 CDS LIA014 NC_008012.1 13079 13909 R trans-aconitate methyltransferase complement(13079..13909) Lawsonia intracellularis PHE/MN1-00 4073401 YP_595578.1 CDS LIA015 NC_008012.1 13950 15080 R hypothetical protein complement(13950..15080) Lawsonia intracellularis PHE/MN1-00 4073402 YP_595579.1 CDS LIA016 NC_008012.1 15288 16061 R hypothetical protein complement(15288..16061) Lawsonia intracellularis PHE/MN1-00 4073403 YP_595580.1 CDS bchE NC_008012.1 16055 17518 R Fe-S oxidoreductase complement(16055..17518) Lawsonia intracellularis PHE/MN1-00 4073414 YP_595581.1 CDS LIA018 NC_008012.1 17553 17906 R hypothetical protein complement(17553..17906) Lawsonia intracellularis PHE/MN1-00 4073404 YP_595582.1 CDS gmhA NC_008012.1 17912 18493 R phosphoheptose isomerase complement(17912..18493) Lawsonia intracellularis PHE/MN1-00 4073395 YP_595583.1 CDS LIA020 NC_008012.1 18514 18888 R hypothetical protein complement(18514..18888) Lawsonia intracellularis PHE/MN1-00 4073405 YP_595584.1 CDS LIA021 NC_008012.1 18943 19275 R hypothetical protein complement(18943..19275) Lawsonia intracellularis PHE/MN1-00 4073406 YP_595585.1 CDS LIA022 NC_008012.1 19278 19784 R cell wall biosynthesis glycosyltransferase complement(19278..19784) Lawsonia intracellularis PHE/MN1-00 4073407 YP_595586.1 CDS galE NC_008012.1 20042 21061 R nucleoside-diphosphate-sugar epimerase complement(20042..21061) Lawsonia intracellularis PHE/MN1-00 4073415 YP_595587.1 CDS LIA024 NC_008012.1 21140 21898 R cell wall biosynthesis glycosyltransferase complement(21140..21898) Lawsonia intracellularis PHE/MN1-00 4073408 YP_595588.1 CDS LIA025 NC_008012.1 21988 22320 R plasmid stabilization system protein complement(21988..22320) Lawsonia intracellularis PHE/MN1-00 4073409 YP_595589.1 CDS LIA026 NC_008012.1 22310 22588 R hypothetical protein complement(22310..22588) Lawsonia intracellularis PHE/MN1-00 4073410 YP_595590.1 CDS LIA027 NC_008012.1 23098 24147 R hypothetical protein complement(23098..24147) Lawsonia intracellularis PHE/MN1-00 4073411 YP_595591.1 CDS LIA028 NC_008012.1 24353 25753 D hypothetical protein 24353..25753 Lawsonia intracellularis PHE/MN1-00 4073412 YP_595592.1 CDS LIA029 NC_008012.1 25951 26709 D chromosome-partitioning ATPase 25951..26709 Lawsonia intracellularis PHE/MN1-00 4073413 YP_595593.1 CDS LIB001 NC_008013.1 404 691 D hypothetical protein 404..691 Lawsonia intracellularis PHE/MN1-00 4073432 YP_595594.1 CDS LIB002 NC_008013.1 2232 2513 R PbsX family transcriptional regulator complement(2232..2513) Lawsonia intracellularis PHE/MN1-00 4073433 YP_595595.1 CDS LIB003 NC_008013.1 2785 3822 D hypothetical protein 2785..3822 Lawsonia intracellularis PHE/MN1-00 4073434 YP_595596.1 CDS LIB004 NC_008013.1 5055 7874 R Asn/Thr/Ser/Val rich protein complement(5055..7874) Lawsonia intracellularis PHE/MN1-00 4073435 YP_595597.1 CDS LIB005 NC_008013.1 8334 9338 R hypothetical protein complement(8334..9338) Lawsonia intracellularis PHE/MN1-00 4073436 YP_595598.1 CDS LIB006 NC_008013.1 10436 12607 D hypothetical protein 10436..12607 Lawsonia intracellularis PHE/MN1-00 4073437 YP_595599.1 CDS asnB NC_008013.1 12772 14652 R putative asparagine synthetase complement(12772..14652) Lawsonia intracellularis PHE/MN1-00 4073429 YP_595600.1 CDS LIB008 NC_008013.1 14668 15459 R hypothetical protein complement(14668..15459) Lawsonia intracellularis PHE/MN1-00 4073438 YP_595601.1 CDS LIB009 NC_008013.1 15453 16469 R hypothetical protein complement(15453..16469) Lawsonia intracellularis PHE/MN1-00 4073439 YP_595602.1 CDS LIB010 NC_008013.1 16482 17606 R DegT/DnrJ/EryC1/StrS aminotransferase family protein complement(16482..17606) Lawsonia intracellularis PHE/MN1-00 4073416 YP_595603.1 CDS pqqE NC_008013.1 17627 18526 R molybdenum cofactor biosynthesis protein complement(17627..18526) Lawsonia intracellularis PHE/MN1-00 4073431 YP_595604.1 CDS LIB012 NC_008013.1 18588 19238 R acetyltransferase complement(18588..19238) Lawsonia intracellularis PHE/MN1-00 4073417 YP_595605.1 CDS LIB013 NC_008013.1 19368 20597 D hypothetical protein 19368..20597 Lawsonia intracellularis PHE/MN1-00 4073418 YP_595606.1 CDS LIB014 NC_008013.1 20757 21587 D hypothetical protein 20757..21587 Lawsonia intracellularis PHE/MN1-00 4073419 YP_595607.1 CDS LIB015 NC_008013.1 21675 22562 D hypothetical protein 21675..22562 Lawsonia intracellularis PHE/MN1-00 4073420 YP_595608.1 CDS LIB016 NC_008013.1 22569 23621 D putative perosamine synthetase 22569..23621 Lawsonia intracellularis PHE/MN1-00 4073421 YP_595609.1 CDS LIB017 NC_008013.1 23628 24695 D hypothetical protein 23628..24695 Lawsonia intracellularis PHE/MN1-00 4073422 YP_595610.1 CDS LIB018 NC_008013.1 24903 26174 D putative molybdopterin cofactor synthesis protein A 24903..26174 Lawsonia intracellularis PHE/MN1-00 4073423 YP_595611.1 CDS LIB019 NC_008013.1 26181 26819 R hypothetical protein complement(26181..26819) Lawsonia intracellularis PHE/MN1-00 4073424 YP_595612.1 CDS LIB020 NC_008013.1 27548 28714 R hypothetical protein complement(27548..28714) Lawsonia intracellularis PHE/MN1-00 4073425 YP_595613.1 CDS LIB021 NC_008013.1 31301 31633 D hypothetical protein 31301..31633 Lawsonia intracellularis PHE/MN1-00 4073426 YP_595614.1 CDS LIB022 NC_008013.1 33665 36469 D hypothetical protein 33665..36469 Lawsonia intracellularis PHE/MN1-00 4073427 YP_595615.1 CDS LIB023 NC_008013.1 36874 38025 D integrase 36874..38025 Lawsonia intracellularis PHE/MN1-00 4073428 YP_595616.1 CDS parA NC_008013.1 38667 39422 D ATPases involved in chromosome partitioning 38667..39422 Lawsonia intracellularis PHE/MN1-00 4073430 YP_595617.1 CDS LIC001 NC_008014.1 525 1610 D integrase/recombinase 525..1610 Lawsonia intracellularis PHE/MN1-00 4073459 YP_595618.1 CDS LIC002 NC_008014.1 2657 3580 D hypothetical protein 2657..3580 Lawsonia intracellularis PHE/MN1-00 4073460 YP_595619.1 CDS epsG NC_008014.1 3754 4872 D putative alpha(1,3)rhamnosyltransferase EpsG 3754..4872 Lawsonia intracellularis PHE/MN1-00 4073511 YP_595620.1 CDS rfbC NC_008014.1 5115 5657 D dTDP-6-deoxy-D-glucose-3,5-epimerase 5115..5657 Lawsonia intracellularis PHE/MN1-00 4073519 YP_595621.1 CDS LIC005 NC_008014.1 5841 6644 D ABC transporter 5841..6644 Lawsonia intracellularis PHE/MN1-00 4073461 YP_595622.1 CDS LIC006 NC_008014.1 6833 7720 D glycosyltransferase 6833..7720 Lawsonia intracellularis PHE/MN1-00 4073462 YP_595623.1 CDS LIC007 NC_008014.1 7836 10205 D hypothetical protein 7836..10205 Lawsonia intracellularis PHE/MN1-00 4073463 YP_595624.1 CDS LIC008 NC_008014.1 10465 11196 D methyltransferase 24 10465..11196 Lawsonia intracellularis PHE/MN1-00 4073464 YP_595625.1 CDS LIC009 NC_008014.1 11293 14562 R hypothetical protein complement(11293..14562) Lawsonia intracellularis PHE/MN1-00 4073465 YP_595626.1 CDS LIC010 NC_008014.1 14573 15277 R putative nucleotidyl transferase complement(14573..15277) Lawsonia intracellularis PHE/MN1-00 4073466 YP_595627.1 CDS mvaK1 NC_008014.1 15277 16257 R putative galactokinase/mevalonate kinase complement(15277..16257) Lawsonia intracellularis PHE/MN1-00 4073515 YP_595628.1 CDS LIC012 NC_008014.1 16567 17556 R putative LmbZ complement(16567..17556) Lawsonia intracellularis PHE/MN1-00 4073467 YP_595629.1 CDS LIC013 NC_008014.1 17553 18434 R dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) complement(17553..18434) Lawsonia intracellularis PHE/MN1-00 4073468 YP_595630.1 CDS ugd NC_008014.1 18568 19872 R UDP-glucose 6-dehydrogenase complement(18568..19872) Lawsonia intracellularis PHE/MN1-00 4073522 YP_595631.1 CDS LIC015 NC_008014.1 19973 20956 R hypothetical protein complement(19973..20956) Lawsonia intracellularis PHE/MN1-00 4073469 YP_595632.1 CDS tal NC_008014.1 20934 21653 R similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase complement(20934..21653) Lawsonia intracellularis PHE/MN1-00 4073521 YP_595633.1 CDS hisJ NC_008014.1 21738 22343 R histidinol phosphatase and related phosphatases complement(21738..22343) Lawsonia intracellularis PHE/MN1-00 4073514 YP_595634.1 CDS LIC018 NC_008014.1 22325 22924 R sugar isomerase family protein complement(22325..22924) Lawsonia intracellularis PHE/MN1-00 4073470 YP_595635.1 CDS LIC019 NC_008014.1 23114 26398 R hypothetical protein complement(23114..26398) Lawsonia intracellularis PHE/MN1-00 4073471 YP_595636.1 CDS LIC020 NC_008014.1 26718 28187 R hypothetical protein complement(26718..28187) Lawsonia intracellularis PHE/MN1-00 4073472 YP_595637.1 CDS LIC021 NC_008014.1 28160 28957 R hypothetical protein complement(28160..28957) Lawsonia intracellularis PHE/MN1-00 4073473 YP_595638.1 CDS LIC022 NC_008014.1 29190 29798 R hypothetical protein complement(29190..29798) Lawsonia intracellularis PHE/MN1-00 4073474 YP_595639.1 CDS galE NC_008014.1 30157 31122 R nucleoside-diphosphate-sugar epimerases complement(30157..31122) Lawsonia intracellularis PHE/MN1-00 4073512 YP_595640.1 CDS LIC024 NC_008014.1 31168 31902 R cell wall biosynthesis glycosyltransferase complement(31168..31902) Lawsonia intracellularis PHE/MN1-00 4073475 YP_595641.1 CDS LIC025 NC_008014.1 32380 32919 R hypothetical protein complement(32380..32919) Lawsonia intracellularis PHE/MN1-00 4073476 YP_595642.1 CDS LIC026 NC_008014.1 32919 33764 R hypothetical protein complement(32919..33764) Lawsonia intracellularis PHE/MN1-00 4073477 YP_595643.1 CDS LIC027 NC_008014.1 34205 35827 D hypothetical protein 34205..35827 Lawsonia intracellularis PHE/MN1-00 4073478 YP_595644.1 CDS LIC028 NC_008014.1 36171 37394 D hypothetical protein 36171..37394 Lawsonia intracellularis PHE/MN1-00 4073479 YP_595645.1 CDS LIC029 NC_008014.1 37950 39563 D hypothetical protein 37950..39563 Lawsonia intracellularis PHE/MN1-00 4073480 YP_595646.1 CDS LIC030 NC_008014.1 39662 41038 D D-alanine export protein 39662..41038 Lawsonia intracellularis PHE/MN1-00 4073481 YP_595647.1 CDS LIC031 NC_008014.1 41380 41661 D hypothetical protein 41380..41661 Lawsonia intracellularis PHE/MN1-00 4073482 YP_595648.1 CDS LIC032 NC_008014.1 41854 42834 R hypothetical protein complement(41854..42834) Lawsonia intracellularis PHE/MN1-00 4073483 YP_595649.1 CDS LIC033 NC_008014.1 42884 43714 R hypothetical protein complement(42884..43714) Lawsonia intracellularis PHE/MN1-00 4073484 YP_595650.1 CDS LIC034 NC_008014.1 43711 44217 R hypothetical protein complement(43711..44217) Lawsonia intracellularis PHE/MN1-00 4073485 YP_595651.1 CDS LIC035 NC_008014.1 44528 45232 R hypothetical protein complement(44528..45232) Lawsonia intracellularis PHE/MN1-00 4073486 YP_595652.1 CDS slt NC_008014.1 45243 45860 R putative lytic murein transglycosylase precursor complement(45243..45860) Lawsonia intracellularis PHE/MN1-00 4073520 YP_595653.1 CDS LIC037 NC_008014.1 46792 51615 D signal peptide 46792..51615 Lawsonia intracellularis PHE/MN1-00 4073487 YP_595654.1 CDS LIC038 NC_008014.1 52068 53210 D glycosyltransferase 52068..53210 Lawsonia intracellularis PHE/MN1-00 4073488 YP_595655.1 CDS LIC039 NC_008014.1 53512 55578 R hypothetical protein complement(53512..55578) Lawsonia intracellularis PHE/MN1-00 4073489 YP_595656.1 CDS LIC040 NC_008014.1 55962 57749 R hypothetical protein complement(55962..57749) Lawsonia intracellularis PHE/MN1-00 4073490 YP_595657.1 CDS LIC041 NC_008014.1 60308 62806 R hypothetical protein complement(60308..62806) Lawsonia intracellularis PHE/MN1-00 4073491 YP_595658.1 CDS LIC042 NC_008014.1 63033 65108 R hypothetical protein complement(63033..65108) Lawsonia intracellularis PHE/MN1-00 4073492 YP_595659.1 CDS LIC043 NC_008014.1 65206 67194 R hypothetical protein complement(65206..67194) Lawsonia intracellularis PHE/MN1-00 4073493 YP_595660.1 CDS LIC044 NC_008014.1 67446 68417 R hypothetical protein complement(67446..68417) Lawsonia intracellularis PHE/MN1-00 4073494 YP_595661.1 CDS LIC045 NC_008014.1 68531 69295 R hypothetical protein complement(68531..69295) Lawsonia intracellularis PHE/MN1-00 4073495 YP_595662.1 CDS LIC046 NC_008014.1 70371 72761 R hypothetical protein complement(70371..72761) Lawsonia intracellularis PHE/MN1-00 4073496 YP_595663.1 CDS LIC047 NC_008014.1 73376 75901 R hypothetical protein complement(73376..75901) Lawsonia intracellularis PHE/MN1-00 4073497 YP_595664.1 CDS LIC048 NC_008014.1 77795 79972 R hypothetical protein complement(77795..79972) Lawsonia intracellularis PHE/MN1-00 4073498 YP_595665.1 CDS LIC049 NC_008014.1 79999 80688 R hypothetical protein complement(79999..80688) Lawsonia intracellularis PHE/MN1-00 4073499 YP_595666.1 CDS LIC050 NC_008014.1 <81658 >83723 R hypothetical protein complement(<81658..>83723) Lawsonia intracellularis PHE/MN1-00 4073500 YP_595667.1 CDS LIC051 NC_008014.1 84342 86378 R hypothetical protein complement(84342..86378) Lawsonia intracellularis PHE/MN1-00 4073501 YP_595668.1 CDS LIC052 NC_008014.1 86569 88623 R hypothetical protein complement(86569..88623) Lawsonia intracellularis PHE/MN1-00 4073502 YP_595669.1 CDS LIC053 NC_008014.1 89091 91199 R hypothetical protein complement(89091..91199) Lawsonia intracellularis PHE/MN1-00 4073503 YP_595670.1 CDS LIC054 NC_008014.1 91646 93478 R hypothetical protein complement(91646..93478) Lawsonia intracellularis PHE/MN1-00 4073504 YP_595671.1 CDS LIC055 NC_008014.1 94015 95874 R hypothetical protein complement(94015..95874) Lawsonia intracellularis PHE/MN1-00 4073524 YP_595672.1 CDS LIC056 NC_008014.1 96167 97960 R hypothetical protein complement(96167..97960) Lawsonia intracellularis PHE/MN1-00 4073525 YP_595673.1 CDS LIC057 NC_008014.1 99530 101632 R hypothetical protein complement(99530..101632) Lawsonia intracellularis PHE/MN1-00 4073526 YP_595674.1 CDS LIC058 NC_008014.1 102038 105190 R hypothetical protein complement(102038..105190) Lawsonia intracellularis PHE/MN1-00 4073527 YP_595675.1 CDS LIC059 NC_008014.1 105648 107375 R hypothetical protein complement(105648..107375) Lawsonia intracellularis PHE/MN1-00 4073528 YP_595676.1 CDS LIC060 NC_008014.1 108008 109867 R hypothetical protein complement(108008..109867) Lawsonia intracellularis PHE/MN1-00 4073529 YP_595677.1 CDS LIC061 NC_008014.1 110667 111209 R hypothetical protein complement(110667..111209) Lawsonia intracellularis PHE/MN1-00 4073530 YP_595678.1 CDS LIC062 NC_008014.1 112870 114228 R hypothetical protein complement(112870..114228) Lawsonia intracellularis PHE/MN1-00 4073531 YP_595679.1 CDS parA NC_008014.1 114721 115545 D ATPases involved in chromosome partitioning 114721..115545 Lawsonia intracellularis PHE/MN1-00 4073516 YP_595680.1 CDS LIC064 NC_008014.1 115557 117053 D hypothetical protein 115557..117053 Lawsonia intracellularis PHE/MN1-00 4073532 YP_595681.1 CDS LIC065 NC_008014.1 117559 120978 R hypothetical protein complement(117559..120978) Lawsonia intracellularis PHE/MN1-00 4073533 YP_595682.1 CDS LIC066 NC_008014.1 121983 123122 D hypothetical protein 121983..123122 Lawsonia intracellularis PHE/MN1-00 4073534 YP_595683.1 CDS LIC067 NC_008014.1 123218 124081 D hypothetical protein 123218..124081 Lawsonia intracellularis PHE/MN1-00 4073535 YP_595684.1 CDS LIC068 NC_008014.1 124084 124533 D hypothetical protein 124084..124533 Lawsonia intracellularis PHE/MN1-00 4073536 YP_595685.1 CDS LIC069 NC_008014.1 124556 125200 D hypothetical protein 124556..125200 Lawsonia intracellularis PHE/MN1-00 4073537 YP_595686.1 CDS LIC070 NC_008014.1 125278 126693 D phage sheath protein 125278..126693 Lawsonia intracellularis PHE/MN1-00 4073538 YP_595687.1 CDS LIC071 NC_008014.1 126956 127345 D hypothetical protein 126956..127345 Lawsonia intracellularis PHE/MN1-00 4073539 YP_595688.1 CDS LIC072 NC_008014.1 127347 127670 D hypothetical protein 127347..127670 Lawsonia intracellularis PHE/MN1-00 4073540 YP_595689.1 CDS LIC073 NC_008014.1 127923 128792 D hypothetical protein 127923..128792 Lawsonia intracellularis PHE/MN1-00 4073541 YP_595690.1 CDS LIC074 NC_008014.1 129105 130370 D hypothetical protein 129105..130370 Lawsonia intracellularis PHE/MN1-00 4073542 YP_595691.1 CDS LIC075 NC_008014.1 130491 131522 D putative phage tail protein 130491..131522 Lawsonia intracellularis PHE/MN1-00 4073543 YP_595692.1 CDS LIC076 NC_008014.1 131586 132182 D hypothetical protein 131586..132182 Lawsonia intracellularis PHE/MN1-00 4073440 YP_595693.1 CDS LIC077 NC_008014.1 132327 133022 R hypothetical protein complement(132327..133022) Lawsonia intracellularis PHE/MN1-00 4073441 YP_595694.1 CDS LIC078 NC_008014.1 133350 133736 R protein synthesis inhibitor, putative complement(133350..133736) Lawsonia intracellularis PHE/MN1-00 4073442 YP_595695.1 CDS LIC079 NC_008014.1 134013 135005 R hypothetical protein complement(134013..135005) Lawsonia intracellularis PHE/MN1-00 4073443 YP_595696.1 CDS LIC080 NC_008014.1 135091 136032 R GDP-L-fucose synthetase-related complement(135091..136032) Lawsonia intracellularis PHE/MN1-00 4073444 YP_595697.1 CDS recQ NC_008014.1 136395 137753 R replicative DNA helicase complement(136395..137753) Lawsonia intracellularis PHE/MN1-00 4073518 YP_595698.1 CDS gmd NC_008014.1 138575 139735 D GDP-D-mannose dehydratase 138575..139735 Lawsonia intracellularis PHE/MN1-00 4073513 YP_595699.1 CDS LIC083 NC_008014.1 140126 140452 D hypothetical protein 140126..140452 Lawsonia intracellularis PHE/MN1-00 4073445 YP_595700.1 CDS LIC084 NC_008014.1 140609 140983 D phage-related membrane protein 140609..140983 Lawsonia intracellularis PHE/MN1-00 4073446 YP_595701.1 CDS LIC085 NC_008014.1 141084 142049 R glycosyl transferase complement(141084..142049) Lawsonia intracellularis PHE/MN1-00 4073447 YP_595702.1 CDS LIC086 NC_008014.1 142046 143107 R glycosyltransferase complement(142046..143107) Lawsonia intracellularis PHE/MN1-00 4073448 YP_595703.1 CDS LIC087 NC_008014.1 143397 143747 D hypothetical protein 143397..143747 Lawsonia intracellularis PHE/MN1-00 4073449 YP_595704.1 CDS LIC088 NC_008014.1 144107 144823 D hypothetical protein 144107..144823 Lawsonia intracellularis PHE/MN1-00 4073450 YP_595705.1 CDS LIC089 NC_008014.1 144828 145394 D hypothetical protein 144828..145394 Lawsonia intracellularis PHE/MN1-00 4073451 YP_595706.1 CDS LIC090 NC_008014.1 146282 147724 R proton/peptide symporter family protein complement(146282..147724) Lawsonia intracellularis PHE/MN1-00 4073452 YP_595707.1 CDS LIC091 NC_008014.1 148401 174641 D hypothetical protein 148401..174641 Lawsonia intracellularis PHE/MN1-00 4073453 YP_595708.1 CDS LIC092 NC_008014.1 174997 176478 D hypothetical protein 174997..176478 Lawsonia intracellularis PHE/MN1-00 4073454 YP_595709.1 CDS LIC093 NC_008014.1 176743 178116 R UDP-N-acetyl-D-mannosaminuronate dehydrogenase complement(176743..178116) Lawsonia intracellularis PHE/MN1-00 4073455 YP_595710.1 CDS LIC094 NC_008014.1 178467 179024 R WblC protein complement(178467..179024) Lawsonia intracellularis PHE/MN1-00 4073456 YP_595711.1 CDS LIC095 NC_008014.1 179021 180190 R DegT/DnrJ/EryC1/StrS family protein complement(179021..180190) Lawsonia intracellularis PHE/MN1-00 4073457 YP_595712.1 CDS LIC096 NC_008014.1 180177 180551 R hypothetical protein complement(180177..180551) Lawsonia intracellularis PHE/MN1-00 4073458 YP_595713.1 CDS LIC097 NC_008014.1 180716 181768 R WblB protein complement(180716..181768) Lawsonia intracellularis PHE/MN1-00 4073505 YP_595714.1 CDS LIC098 NC_008014.1 182091 183431 R methyl-accepting chemotaxis protein complement(182091..183431) Lawsonia intracellularis PHE/MN1-00 4073506 YP_595715.1 CDS LIC099 NC_008014.1 184429 185472 R hypothetical protein complement(184429..185472) Lawsonia intracellularis PHE/MN1-00 4073507 YP_595716.1 CDS LIC100 NC_008014.1 186166 186576 D hypothetical protein 186166..186576 Lawsonia intracellularis PHE/MN1-00 4073508 YP_595717.1 CDS LIC101 NC_008014.1 186732 187613 D hypothetical protein 186732..187613 Lawsonia intracellularis PHE/MN1-00 4073509 YP_595718.1 CDS yhjA NC_008014.1 188379 189776 D putative cytochrome C peroxidase 188379..189776 Lawsonia intracellularis PHE/MN1-00 4073523 YP_595719.1 CDS pilJ NC_008014.1 190321 192417 R methyl-accepting chemotaxis protein complement(190321..192417) Lawsonia intracellularis PHE/MN1-00 4073517 YP_595720.1 CDS LIC104 NC_008014.1 193810 194466 R hypothetical protein complement(193810..194466) Lawsonia intracellularis PHE/MN1-00 4073510 LIt01 tRNA LIt01 NC_008011.1 9354 9430 R tRNA-Arg complement(9354..9430) Lawsonia intracellularis PHE/MN1-00 4794316 LIt02 tRNA LIt02 NC_008011.1 61246 61322 R tRNA-Met complement(61246..61322) Lawsonia intracellularis PHE/MN1-00 4794314 LIt03 tRNA LIt03 NC_008011.1 110284 110376 D tRNA-Ser 110284..110376 Lawsonia intracellularis PHE/MN1-00 4794311 LIt04 tRNA LIt04 NC_008011.1 138558 138634 R tRNA-Arg complement(138558..138634) Lawsonia intracellularis PHE/MN1-00 4794313 LIt05 tRNA LIt05 NC_008011.1 167857 167943 D tRNA-Leu 167857..167943 Lawsonia intracellularis PHE/MN1-00 4794335 LIt06 tRNA LIt06 NC_008011.1 177565 177658 D tRNA-Ser 177565..177658 Lawsonia intracellularis PHE/MN1-00 4794330 LIt07 tRNA LIt07 NC_008011.1 181753 181829 R tRNA-Glu complement(181753..181829) Lawsonia intracellularis PHE/MN1-00 4794307 LIt08 tRNA LIt08 NC_008011.1 206575 206650 R tRNA-Phe complement(206575..206650) Lawsonia intracellularis PHE/MN1-00 4794340 LIt09 tRNA LIt09 NC_008011.1 267526 267601 D tRNA-Val 267526..267601 Lawsonia intracellularis PHE/MN1-00 4794332 LIt10 tRNA LIt10 NC_008011.1 360442 360517 D tRNA-Val 360442..360517 Lawsonia intracellularis PHE/MN1-00 4794325 LIt11 tRNA LIt11 NC_008011.1 481534 481609 R tRNA-Lys complement(481534..481609) Lawsonia intracellularis PHE/MN1-00 4794319 LIt12 tRNA LIt12 NC_008011.1 503154 503245 D tRNA-Ser 503154..503245 Lawsonia intracellularis PHE/MN1-00 4794317 LIt13 tRNA LIt13 NC_008011.1 522074 522148 R tRNA-Gly complement(522074..522148) Lawsonia intracellularis PHE/MN1-00 4794338 LIt14 tRNA LIt14 NC_008011.1 522152 522226 R tRNA-Cys complement(522152..522226) Lawsonia intracellularis PHE/MN1-00 4794303 LIt15 tRNA LIt15 NC_008011.1 528936 529011 D tRNA-Lys 528936..529011 Lawsonia intracellularis PHE/MN1-00 4794337 LIt16 tRNA LIt16 NC_008011.1 555158 555243 D tRNA-Leu 555158..555243 Lawsonia intracellularis PHE/MN1-00 4794323 LIt17 tRNA LIt17 NC_008011.1 565705 565778 D tRNA-Gln 565705..565778 Lawsonia intracellularis PHE/MN1-00 4794327 LIt18 tRNA LIt18 NC_008011.1 674719 674794 R tRNA-Ala complement(674719..674794) Lawsonia intracellularis PHE/MN1-00 4794312 LIt19 tRNA LIt19 NC_008011.1 674864 674940 R tRNA-Ile complement(674864..674940) Lawsonia intracellularis PHE/MN1-00 4794301 LIt20 tRNA LIt20 NC_008011.1 692831 692917 R tRNA-Leu complement(692831..692917) Lawsonia intracellularis PHE/MN1-00 4794310 LIt21 tRNA LIt21 NC_008011.1 789334 789419 R tRNA-Leu complement(789334..789419) Lawsonia intracellularis PHE/MN1-00 4794329 LIt22 tRNA LIt22 NC_008011.1 839287 839363 R tRNA-Pro complement(839287..839363) Lawsonia intracellularis PHE/MN1-00 4794324 LIt23 tRNA LIt23 NC_008011.1 870279 870355 R tRNA-Pro complement(870279..870355) Lawsonia intracellularis PHE/MN1-00 4794333 LIt24 tRNA LIt24 NC_008011.1 896202 896291 D tRNA-Ser 896202..896291 Lawsonia intracellularis PHE/MN1-00 4794315 LIt25 tRNA LIt25 NC_008011.1 920117 920192 D tRNA-Gln 920117..920192 Lawsonia intracellularis PHE/MN1-00 4794305 LIt26 tRNA LIt26 NC_008011.1 986912 986995 D tRNA-Leu 986912..986995 Lawsonia intracellularis PHE/MN1-00 4794321 LIt27 tRNA LIt27 NC_008011.1 1005511 1005586 R tRNA-Thr complement(1005511..1005586) Lawsonia intracellularis PHE/MN1-00 4794326 LIt28 tRNA LIt28 NC_008011.1 1041691 1041766 D tRNA-His 1041691..1041766 Lawsonia intracellularis PHE/MN1-00 4794322 LIt29 tRNA LIt29 NC_008011.1 1044859 1044934 D tRNA-Ala 1044859..1044934 Lawsonia intracellularis PHE/MN1-00 4794318 LIt30 tRNA LIt30 NC_008011.1 1062113 1062189 R tRNA-Arg complement(1062113..1062189) Lawsonia intracellularis PHE/MN1-00 4794298 LIt31 tRNA LIt31 NC_008011.1 1099129 1099205 D tRNA-Arg 1099129..1099205 Lawsonia intracellularis PHE/MN1-00 4794308 LIt32 tRNA LIt32 NC_008011.1 1163610 1163686 R tRNA-Trp complement(1163610..1163686) Lawsonia intracellularis PHE/MN1-00 4794309 LIt33 tRNA LIt33 NC_008011.1 1165203 1165279 R tRNA-Gly complement(1165203..1165279) Lawsonia intracellularis PHE/MN1-00 4794299 LIt34 tRNA LIt34 NC_008011.1 1165354 1165439 R tRNA-Tyr complement(1165354..1165439) Lawsonia intracellularis PHE/MN1-00 4794331 LIt35 tRNA LIt35 NC_008011.1 1165443 1165518 R tRNA-Thr complement(1165443..1165518) Lawsonia intracellularis PHE/MN1-00 4794336 LIt36 tRNA LIt36 NC_008011.1 1256386 1256461 R tRNA-Thr complement(1256386..1256461) Lawsonia intracellularis PHE/MN1-00 4794334 LIt37 tRNA LIt37 NC_008011.1 1267851 1267926 D tRNA-Asn 1267851..1267926 Lawsonia intracellularis PHE/MN1-00 4794300 LIt38 tRNA LIt38 NC_008011.1 1299965 1300040 D tRNA-Met 1299965..1300040 Lawsonia intracellularis PHE/MN1-00 4794328 LIt39 tRNA LIt39 NC_008011.1 1382574 1382649 D tRNA-Val 1382574..1382649 Lawsonia intracellularis PHE/MN1-00 4794320 LIt40 tRNA LIt40 NC_008011.1 1382805 1382881 D tRNA-Asp 1382805..1382881 Lawsonia intracellularis PHE/MN1-00 4794306 LIt41 tRNA LIt41 NC_008011.1 1405509 1405585 D tRNA-Ile 1405509..1405585 Lawsonia intracellularis PHE/MN1-00 4794304 LIt42 tRNA LIt42 NC_008011.1 1405655 1405730 D tRNA-Ala 1405655..1405730 Lawsonia intracellularis PHE/MN1-00 4794302 LIt43 tRNA LIt43 NC_008011.1 1453676 1453752 D tRNA-Met 1453676..1453752 Lawsonia intracellularis PHE/MN1-00 4794339 LI_r01 rRNA LI_r01 NC_008011.1 671512 671629 R 5S ribosomal RNA complement(671512..671629) Lawsonia intracellularis PHE/MN1-00 4924565 LI_r02 rRNA LI_r02 NC_008011.1 671667 674586 R 23S ribosomal RNA complement(671667..674586) Lawsonia intracellularis PHE/MN1-00 4924566 LI_r03 rRNA LI_r03 NC_008011.1 674999 676543 R 16S ribosomal RNA complement(674999..676543) Lawsonia intracellularis PHE/MN1-00 4924569 LI_r04 rRNA LI_r04 NC_008011.1 1403906 1405450 D 16S ribosomal RNA 1403906..1405450 Lawsonia intracellularis PHE/MN1-00 4924568 LI_r05 rRNA LI_r05 NC_008011.1 1405863 1408782 D 23S ribosomal RNA 1405863..1408782 Lawsonia intracellularis PHE/MN1-00 4924570 LI_r06 rRNA LI_r06 NC_008011.1 1408820 1408937 D 5S ribosomal RNA 1408820..1408937 Lawsonia intracellularis PHE/MN1-00 4924567