-- dump date   	20120504_151726
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_001722962.1	COG1715V
YP_001722967.1	COG1192D
YP_001722970.1	COG5039GM
YP_001722971.1	COG0477GEPR
YP_001722972.1	related to diketogulonate reductase; COG0656R
YP_001722974.1	COG2261S
YP_001722975.1	COG4291S
YP_001722976.1	COG1302S
YP_001722979.1	COG2261S
YP_001722980.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001722981.1	COG2801L
YP_001722982.1	COG2801L
YP_001722983.1	COG2801L
YP_001722985.1	COG0477GEPR
YP_001722986.1	COG1554G
YP_001722987.1	COG2017G; similar to enzyme
YP_001722988.1	COG0637R
YP_001722989.1	COG0582L
YP_001722990.1	COG0664T
YP_001722991.1	COG0783P
YP_001722992.1	COG2608P
YP_001722993.1	COG2217P
YP_001722994.1	COG2132Q
YP_001722995.1	COG2801L
YP_001723000.1	COG1396K
YP_001723001.1	COG1396K
YP_001723002.1	COG1396K
YP_001723004.1	COG0526OC; TIGR01068
YP_001723005.1	COG0526OC
YP_001723006.1	COG0492O; TIGR01292
YP_001723007.1	COG2761Q
YP_001723008.1	COG1249C
YP_001723009.1	COG0640K
YP_001723010.1	COG0526OC
YP_001723011.1	COG1961L
YP_001723012.1	COG2801L
YP_001727216.1	COG0582L
YP_001727218.1	COG0454KR
YP_001727222.1	COG2963L
YP_001727223.1	COG3682K
YP_001727225.1	COG2217P
YP_001727227.1	COG4619R
YP_001727228.1	COG0390R
YP_001727231.1	COG1961L
YP_001727232.1	COG2963L
YP_001727233.1	COG2801L
YP_001727235.1	COG3764M
YP_001727242.1	COG0394T
YP_001727246.1	COG1192D
YP_001727248.1	COG1396K
YP_001727253.1	COG1674D
YP_001727273.1	COG2801L
YP_001727278.1	COG0593L; TIGR00362
YP_001727279.1	COG0592L; TIGR00663
YP_001727280.1	COG2501S
YP_001727281.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_001727282.1	COG0187L; TIGR01059
YP_001727283.1	COG0188L; TIGR01063
YP_001727284.1	COG1983KT
YP_001727286.1	COG3595S
YP_001727287.1	COG1695K
YP_001727290.1	COG0845M
YP_001727291.1	COG1136V
YP_001727292.1	COG0577V
YP_001727293.1	COG0178L
YP_001727294.1	COG1396K
YP_001727295.1	COG0477GEPR
YP_001727296.1	COG1846K
YP_001727297.1	COG1266R
YP_001727298.1	COG1131V
YP_001727300.1	COG5523S
YP_001727302.1	COG1396K
YP_001727303.1	COG0162J; TIGR00234
YP_001727304.1	COG1052CHR; similar to dehydrogenase
YP_001727305.1	COG2084I; similar to beta-hydroxyacid dehydrogenase
YP_001727306.1	COG2918H
YP_001727308.1	COG2963L
YP_001727309.1	COG2801L
YP_001727310.1	C-terminal ATPase domain; COG2972T
YP_001727311.1	COG3279KT
YP_001727313.1	COG0561R
YP_001727314.1	COG0657I
YP_001727315.1	COG3477S
YP_001727318.1	COG1725K
YP_001727319.1	COG1131V
YP_001727321.1	COG1131V
YP_001727322.1	COG1277R
YP_001727323.1	related to diketogulonate reductase; COG0656R
YP_001727324.1	COG0803P
YP_001727325.1	COG1846K
YP_001727327.1	COG1116P
YP_001727328.1	COG0737F
YP_001727329.1	COG0364G; TIGR00871
YP_001727330.1	COG0657I
YP_001727331.1	COG0627R
YP_001727332.1	COG0657I
YP_001727333.1	COG2211G; similar to transporter
YP_001727334.1	COG1073R
YP_001727335.1	COG1609K
YP_001727336.1	COG0477GEPR
YP_001727337.1	COG1757C; TIGR00931
YP_001727338.1	COG2855S
YP_001727339.1	COG0583K
YP_001727340.1	similar to permease
YP_001727344.1	COG1476K
YP_001727345.1	COG0406G
YP_001727346.1	COG0514L; TIGR01389
YP_001727347.1	COG2211G
YP_001727348.1	COG2211G
YP_001727349.1	COG3507G
YP_001727350.1	COG2017G; similar to enzyme
YP_001727351.1	COG1940KG
YP_001727352.1	catalyzes the interconversion of D-xylose to D-xylulose
YP_001727353.1	COG1070G; TIGR01312
YP_001727355.1	COG0475P
YP_001727356.1	COG0394T
YP_001727357.1	COG2350S
YP_001727358.1	COG3759S
YP_001727361.1	COG1396K
YP_001727367.1	COG3378R
YP_001727370.1	COG2801L
YP_001727371.1	COG2963L
YP_001727372.1	COG0582L
YP_001727376.1	COG0477GEPR
YP_001727377.1	COG1051F
YP_001727381.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001727382.1	COG2390K
YP_001727383.1	COG0281C
YP_001727384.1	COG3053C; TIGR00124
YP_001727385.1	acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate
YP_001727386.1	COG2301G
YP_001727387.1	COG3051C
YP_001727388.1	Includes: Apo-citrate lyase phosphoribosyl-dephospho- CoA transferase (Holo-ACP synthase) (Holo-citrate lyase synthase) (Apo-ACP nucleodityltransferase); 2-(5''-triphosphoribosyl)- 3'-dephosphocoenzyme-A synthase (2-(5''- triphosphoribosyl)-3'-dephospho-CoA synthase); COG1767H
YP_001727389.1	COG0596R
YP_001727390.1	COG3493C
YP_001727391.1	COG1840P
YP_001727392.1	COG3842E
YP_001727394.1	COG1178P
YP_001727395.1	COG0584C
YP_001727396.1	COG1012C
YP_001727397.1	COG1511S
YP_001727398.1	COG1959K
YP_001727399.1	COG2207K
YP_001727401.1	COG0657I
YP_001727402.1	COG1940KG
YP_001727403.1	COG2723G
YP_001727404.1	COG3711K
YP_001727405.1	COG1263G
YP_001727406.1	COG1846K
YP_001727407.1	COG1249C
YP_001727408.1	COG0604CR; similar to Zn-dependent oxidoreductase
YP_001727409.1	COG3759S
YP_001727410.1	COG5263R
YP_001727411.1	FOG: GGDEF domain; COG2199T
YP_001727412.1	FOG: EAL domain; COG4943T
YP_001727413.1	COG0038P
YP_001727414.1	COG1396K
YP_001727416.1	COG0488R
YP_001727417.1	COG0563F
YP_001727418.1	COG0787M; TIGR00492
YP_001727419.1	COG0136E; TIGR01296
YP_001727420.1	COG1434S
YP_001727421.1	COG1126E
YP_001727422.1	COG0834ET
YP_001727423.1	COG0765E
YP_001727424.1	COG0765E
YP_001727425.1	COG4166E
YP_001727426.1	COG0601EP
YP_001727427.1	COG1173EP
YP_001727428.1	COG0444EP
YP_001727429.1	COG4608E
YP_001727430.1	COG3590O
YP_001727432.1	COG1027E
YP_001727433.1	COG0120G; TIGR00021
YP_001727435.1	COG0756F
YP_001727436.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_001727437.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_001727438.1	COG0604CR; similar to Zn-dependent oxidoreductase
YP_001727439.1	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs
YP_001727441.1	COG4720S
YP_001727442.1	COG1122P
YP_001727443.1	COG0619P; similar to transporter
YP_001727444.1	COG0624E; similar to deacylase
YP_001727446.1	COG0360J; TIGR00166
YP_001727447.1	COG0629L
YP_001727448.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_001727449.1	COG3887T
YP_001727450.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_001727451.1	COG0305L; TIGR00665
YP_001727452.1	COG2606S
YP_001727453.1	COG2188K
YP_001727454.1	COG3957G
YP_001727455.1	catalyzes the formation of L-histidinol from L-histidinol phosphate
YP_001727456.1	COG0546R
YP_001727457.1	COG1443I
YP_001727458.1	COG0477GEPR
YP_001727459.1	COG0561R
YP_001727460.1	COG2077O
YP_001727461.1	COG0462FE
YP_001727462.1	COG0745TK
YP_001727463.1	COG5002T
YP_001727466.1	typically periplasmic, contains C-terminal PDZ domain; COG0265O
YP_001727467.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_001727468.1	COG0477GEPR
YP_001727469.1	COG1194L; TIGR01084
YP_001727470.1	COG0628R
YP_001727472.1	COG2265J; TIGR00479
YP_001727474.1	COG0542O
YP_001727476.1	COG5579S
YP_001727477.1	COG1893H; TIGR00745
YP_001727478.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001727479.1	COG1316K
YP_001727481.1	COG0730R
YP_001727483.1	COG0833E
YP_001727485.1	COG1077D
YP_001727487.1	COG0772D
YP_001727489.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_001727491.1	COG0589T; similar to nucleotide-binding protein
YP_001727492.1	related to the helicase subunit of the Holliday junction resolvase; COG2256L
YP_001727493.1	COG5506S
YP_001727494.1	COG0522J; TIGR01017
YP_001727495.1	acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation
YP_001727496.1	COG0531E
YP_001727497.1	COG0194F
YP_001727498.1	COG0436E
YP_001727499.1	COG1052CHR; similar to dehydrogenase
YP_001727500.1	COG3641R
YP_001727501.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_001727502.1	COG0787M; TIGR00492
YP_001727503.1	COG2337T
YP_001727505.1	COG0525J; TIGR00422
YP_001727507.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_001727508.1	FOG: LysM repeat; COG1388M
YP_001727510.1	FOG: LysM repeat; COG1388M
YP_001727511.1	COG2348V
YP_001727512.1	COG1316K
YP_001727513.1	COG0671I
YP_001727514.1	COG0248FP
YP_001727515.1	COG1257I; TIGR00532
YP_001727517.1	COG0846K
YP_001727518.1	COG1230P
YP_001727519.1	COG1914P
YP_001727520.1	COG0589T; similar to nucleotide-binding protein
YP_001727521.1	COG4300P
YP_001727522.1	COG0640K
YP_001727524.1	COG1442M
YP_001727525.1	catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides
YP_001727526.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_001727527.1	COG1192D
YP_001727528.1	COG1475K
YP_001727529.1	COG4481S
YP_001727530.1	COG0012J
YP_001727532.1	COG0745TK
YP_001727533.1	COG5002T
YP_001727534.1	COG1686M
YP_001727535.1	COG0363G; TIGR00502
YP_001727536.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_001727537.1	COG2804NU
YP_001727538.1	COG1459NU
YP_001727544.1	COG0827L
YP_001727545.1	COG0282C; TIGR00016
YP_001727546.1	COG1705NU
YP_001727547.1	COG4975G
YP_001727548.1	COG0782K
YP_001727549.1	COG4485S
YP_001727550.1	COG0768M
YP_001727551.1	COG0702MG
YP_001727552.1	COG0714R
YP_001727556.1	COG4732S
YP_001727557.1	COG2145H
YP_001727558.1	COG0351H
YP_001727559.1	COG0352H
YP_001727560.1	COG2035S
YP_001727561.1	COG1164E
YP_001727562.1	COG1073R
YP_001727563.1	COG0263E
YP_001727564.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_001727565.1	COG1957F
YP_001727566.1	COG0492O
YP_001727568.1	COG1126E
YP_001727569.1	COG0765E
YP_001727570.1	COG0834ET
YP_001727571.1	COG1418R
YP_001727572.1	COG0143J
YP_001727573.1	COG0340H
YP_001727574.1	COG0057G
YP_001727576.1	COG0764I
YP_001727577.1	COG1846K
YP_001727578.1	COG0332I
YP_001727579.1	COG0236IQ
YP_001727580.1	related to 2-nitropropane dioxygenase; COG2070R
YP_001727581.1	COG0331I
YP_001727582.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001727583.1	COG0304IQ
YP_001727584.1	COG0511I; TIGR00531
YP_001727585.1	COG0764I
YP_001727586.1	COG0439I
YP_001727587.1	COG0777I; TIGR00515
YP_001727588.1	COG0825I
YP_001727591.1	COG2226H
YP_001727592.1	In Listeria monocytogenes this protein binds a specific sites on DNA, influencing the topology and transcription; regulates flaA, proU and ompC; is osmoregulated
YP_001727594.1	COG0789K
YP_001727595.1	COG1396K
YP_001727598.1	COG1670J
YP_001727600.1	COG0702MG
YP_001727601.1	similar to mitochondrial benzodiazepine receptor; COG3476T
YP_001727602.1	COG4283S
YP_001727603.1	COG1309K
YP_001727604.1	COG2272I
YP_001727607.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_001727610.1	COG1193L
YP_001727611.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_001727612.1	COG5523S
YP_001727613.1	COG0237H; TIGR00152
YP_001727614.1	COG3611L
YP_001727615.1	COG1484L
YP_001727616.1	COG5438S
YP_001727617.1	COG5438S
YP_001727621.1	COG1744R
YP_001727622.1	COG0834ET
YP_001727623.1	COG1126E
YP_001727624.1	COG0834ET
YP_001727625.1	COG4469R
YP_001727626.1	COG1164E; TIGR00181
YP_001727627.1	COG0295F; TIGR01354
YP_001727628.1	COG0111HE
YP_001727629.1	COG1609K
YP_001727630.1	COG1063ER; similar to Zn-dependent dehydrogenase
YP_001727632.1	similar to lyase
YP_001727633.1	COG0366G
YP_001727634.1	COG1940KG
YP_001727635.1	COG1733K
YP_001727636.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_001727637.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_001727638.1	COG0766M; TIGR01072
YP_001727639.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_001727640.1	COG2265J; TIGR00479
YP_001727641.1	COG0770M
YP_001727642.1	COG1680V
YP_001727643.1	COG0513LKJ
YP_001727644.1	COG0285H
YP_001727645.1	COG0477GEPR
YP_001727646.1	COG2003L
YP_001727647.1	COG0343J; TIGR00430
YP_001727648.1	COG1862U; TIGR00739
YP_001727649.1	COG0596R
YP_001727650.1	COG2898S
YP_001727651.1	COG1896R
YP_001727652.1	COG0494LR
YP_001727653.1	COG1136V
YP_001727654.1	COG1132V
YP_001727655.1	COG1132V
YP_001727656.1	COG0438M
YP_001727657.1	COG0438M
YP_001727658.1	COG0392S
YP_001727660.1	COG1368M; similar alkaline phosphatase superfamily
YP_001727661.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_001727662.1	COG0178L; TIGR00630
YP_001727663.1	COG0391S
YP_001727664.1	COG1481S
YP_001727665.1	COG0740OU; TIGR00493
YP_001727666.1	COG1052CHR
YP_001727667.1	COG3641R
YP_001727668.1	related to metalloendopeptidases
YP_001727669.1	COG2179R
YP_001727670.1	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
YP_001727671.1	COG1534J
YP_001727672.1	COG1057H; TIGR00482
YP_001727673.1	COG1713H
YP_001727674.1	COG0799S
YP_001727675.1	COG0500QR
YP_001727676.1	COG1323R
YP_001727677.1	COG1399R
YP_001727678.1	COG0745TK
YP_001727679.1	COG0642T
YP_001727680.1	COG1254C
YP_001727681.1	COG0706U
YP_001727682.1	COG0566J
YP_001727683.1	COG1314U; TIGR00810
YP_001727684.1	COG0557K
YP_001727685.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_001727686.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
YP_001727687.1	COG4768R
YP_001727692.1	Essential for recycling GMP and indirectly, cGMP
YP_001727693.1	COG1758K; TIGR00690
YP_001727694.1	COG0652O
YP_001727695.1	COG1098J
YP_001727697.1	COG1393P
YP_001727698.1	enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence
YP_001727699.1	COG0607P
YP_001727700.1	COG0095H
YP_001727701.1	COG1071C
YP_001727702.1	COG0022C
YP_001727703.1	COG0508C
YP_001727704.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_001727705.1	COG0596R
YP_001727706.1	COG0492O
YP_001727707.1	COG0450O
YP_001727708.1	COG1309K
YP_001727710.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001727711.1	COG0477GEPR
YP_001727714.1	COG0584C
YP_001727715.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_001727716.1	COG0025P
YP_001727717.1	COG0308E
YP_001727718.1	COG0477GEPR
YP_001727720.1	COG1078R
YP_001727721.1	COG4506S
YP_001727722.1	participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
YP_001727723.1	COG1113E; similar to permease
YP_001727724.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_001727725.1	carries the fatty acid chain in fatty acid biosynthesis
YP_001727726.1	COG1956T
YP_001727727.1	COG1249C
YP_001727728.1	COG1732M
YP_001727729.1	COG3091S
YP_001727730.1	COG0561R
YP_001727732.1	COG1266R
YP_001727733.1	COG0006E
YP_001727734.1	COG1609K
YP_001727735.1	COG1835I
YP_001727736.1	COG3527Q; TIGR01252
YP_001727737.1	COG0572F; TIGR00235
YP_001727738.1	COG1737K
YP_001727739.1	similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate
YP_001727740.1	COG1070G; TIGR01314
YP_001727741.1	COG2610GE; similar to permease
YP_001727742.1	COG0531E
YP_001727743.1	catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
YP_001727744.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001727745.1	COG4472S
YP_001727746.1	involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_001727747.1	COG3906S
YP_001727748.1	COG1271C
YP_001727749.1	COG1294C; TIGR00203
YP_001727750.1	COG4988CO
YP_001727751.1	COG4987CO
YP_001727752.1	COG1705NU
YP_001727753.1	COG0210L; TIGR01073
YP_001727754.1	COG0272L; TIGR00575
YP_001727755.1	COG4851R
YP_001727756.1	COG1570L; TIGR00237
YP_001727757.1	COG1722L; TIGR01280
YP_001727758.1	COG0142H
YP_001727759.1	COG1189J; TIGR00478
YP_001727760.1	COG1438K
YP_001727761.1	COG0497L; TIGR00634
YP_001727762.1	COG2252R
YP_001727763.1	COG0588G
YP_001727764.1	COG1363G
YP_001727765.1	COG0772D
YP_001727766.1	COG4471S
YP_001727767.1	COG0742L
YP_001727768.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_001727769.1	COG3480T
YP_001727771.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_001727772.1	COG1488H
YP_001727773.1	COG0802R
YP_001727774.1	COG0454KR; similar to acetyltransferase
YP_001727775.1	COG2176L; similar to 3'-5' exonuclease
YP_001727776.1	COG0708L; TIGR00195
YP_001727777.1	COG0063G
YP_001727779.1	COG0624E; similar to deacylase
YP_001727780.1	COG1056H
YP_001727781.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001727782.1	COG1457F
YP_001727783.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_001727784.1	binds and unfolds substrates as part of the ClpXP protease
YP_001727785.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_001727786.1	COG1198L; TIGR00595
YP_001727787.1	COG0223J; TIGR00460
YP_001727788.1	COG0144J; TIGR00563
YP_001727789.1	COG0631T
YP_001727790.1	COG0515RTKL
YP_001727791.1	COG1162R
YP_001727792.1	COG0036G; TIGR01163
YP_001727793.1	COG1564H
YP_001727794.1	COG0526OC; TIGR01068
YP_001727795.1	required for 70S ribosome assembly
YP_001727796.1	COG1302S
YP_001727797.1	related to dihydroxyacetone kinase; COG1461R
YP_001727800.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_001727801.1	COG0275M; TIGR00006
YP_001727803.1	COG0768M
YP_001727804.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_001727805.1	COG0771M; TIGR01087
YP_001727806.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_001727807.1	COG1589M
YP_001727808.1	COG0849D; TIGR01174
YP_001727809.1	COG0206D; TIGR00065
YP_001727810.1	COG1799S
YP_001727811.1	COG0762S
YP_001727812.1	COG2302S
YP_001727813.1	COG3599D
YP_001727814.1	COG0060J; TIGR00392
YP_001727815.1	COG1440G
YP_001727816.1	COG1447G
YP_001727818.1	COG3971Q
YP_001727819.1	COG1114E; TIGR00796
YP_001727820.1	COG0035F; TIGR01091
YP_001727821.1	COG3641R
YP_001727822.1	COG0683E
YP_001727823.1	COG0559E
YP_001727824.1	COG4177E
YP_001727825.1	COG0411E
YP_001727826.1	COG0410E
YP_001727827.1	COG0833E
YP_001727828.1	converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines
YP_001727830.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_001727831.1	COG0280C; TIGR00651
YP_001727833.1	COG1132V
YP_001727834.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_001727835.1	COG0111HE
YP_001727836.1	COG1267I
YP_001727837.1	COG0217S
YP_001727838.1	COG0716C
YP_001727839.1	COG0580G
YP_001727841.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_001727842.1	COG1113E; similar to permease
YP_001727843.1	COG4330S
YP_001727844.1	COG0290J
YP_001727845.1	COG0291J; TIGR00001
YP_001727846.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_001727848.1	COG0595R
YP_001727849.1	similar to helicase
YP_001727850.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001727851.1	COG1126E
YP_001727852.1	COG0120G; TIGR00021
YP_001727853.1	COG0589T; similar to nucleotide-binding protein
YP_001727854.1	COG0652O
YP_001727856.1	COG0671I
YP_001727857.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_001727858.1	COG2244R
YP_001727861.1	COG1704S
YP_001727862.1	putative metalloprotease
YP_001727864.1	COG0516F
YP_001727865.1	COG0516F
YP_001727866.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_001727870.1	COG0577V
YP_001727871.1	COG1136V
YP_001727872.1	COG0642T
YP_001727873.1	COG0745TK
YP_001727874.1	functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC
YP_001727875.1	COG0744M
YP_001727876.1	COG4474S
YP_001727877.1	COG3599D
YP_001727878.1	COG0834ET
YP_001727879.1	COG0041F
YP_001727880.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_001727881.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_001727882.1	COG1828F; TIGR00302
YP_001727883.1	COG0047F
YP_001727884.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_001727885.1	COG0034F; TIGR01134
YP_001727886.1	COG0150F
YP_001727887.1	COG0299F; TIGR00639
YP_001727888.1	involved in de novo purine biosynthesis
YP_001727889.1	COG0494LR
YP_001727890.1	COG0151F
YP_001727891.1	COG2759F
YP_001727892.1	COG0627R
YP_001727893.1	COG0477GEPR
YP_001727894.1	COG0015F; TIGR00928
YP_001727895.1	COG0634F; TIGR01203
YP_001727896.1	catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate
YP_001727897.1	COG1577I; TIGR01220
YP_001727898.1	COG3407I; TIGR01240
YP_001727899.1	COG0628R
YP_001727900.1	COG0219J
YP_001727901.1	COG1674D
YP_001727903.1	COG1001F; TIGR01178
YP_001727904.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_001727905.1	COG0020I; TIGR00055
YP_001727906.1	COG0575I
YP_001727907.1	COG0750M
YP_001727908.1	COG0442J; TIGR00409
YP_001727909.1	COG2176L; TIGR01405
YP_001727910.1	COG3223S
YP_001727911.1	COG0524G
YP_001727912.1	COG0144J
YP_001727913.1	COG1744R
YP_001727915.1	COG0406G
YP_001727916.1	COG0507L
YP_001727917.1	COG0462FE
YP_001727919.1	related to aryl-alcohol dehydrogenases; COG0667C
YP_001727922.1	COG1577I; TIGR00549
YP_001727923.1	COG2176L
YP_001727925.1	COG0436E
YP_001727926.1	COG0017J; TIGR00457
YP_001727927.1	COG3935L
YP_001727929.1	COG0116L
YP_001727930.1	COG0436E
YP_001727931.1	COG0454KR; similar to acetyltransferase
YP_001727932.1	related to nitroreductase; COG3560R
YP_001727933.1	COG1705NU
YP_001727935.1	COG1609K
YP_001727936.1	COG0477GEPR
YP_001727937.1	COG1554G
YP_001727938.1	COG0637R
YP_001727939.1	COG1609K
YP_001727940.1	COG0366G
YP_001727941.1	COG0477GEPR
YP_001727942.1	COG0366G
YP_001727943.1	COG0124J; TIGR00442
YP_001727944.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_001727945.1	COG1284S
YP_001727946.1	COG1113E; similar to permease
YP_001727947.1	COG2508TQ
YP_001727948.1	COG0477GEPR
YP_001727949.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_001727950.1	COG1610S
YP_001727951.1	COG2996S
YP_001727952.1	COG4974L
YP_001727954.1	COG1354S
YP_001727955.1	COG1386K; TIGR00281
YP_001727956.1	COG1187J; similar to pseudouridylate synthase
YP_001727957.1	COG3601S
YP_001727959.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_001727960.1	COG0539J
YP_001727961.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_001727962.1	COG0776L
YP_001727964.1	related to diketogulonate reductase; COG0656R
YP_001727965.1	COG3237S
YP_001727966.1	FOG: TPR repeat; COG0457R
YP_001727967.1	COG0617J
YP_001727968.1	COG0262H
YP_001727969.1	COG1307S
YP_001727970.1	COG1957F
YP_001727972.1	COG0021G
YP_001727973.1	COG0169E
YP_001727974.1	COG2876E
YP_001727975.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_001727976.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_001727977.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_001727978.1	COG0287E
YP_001727979.1	COG0703E
YP_001727981.1	COG0710E
YP_001727983.1	COG0587L
YP_001727984.1	COG0469G; TIGR01064
YP_001727985.1	COG0004P; TIGR00836
YP_001727986.1	COG1702T
YP_001727987.1	COG0319R
YP_001727988.1	COG0818M
YP_001727989.1	COG1159R; TIGR00436
YP_001727990.1	COG1381L; TIGR00613
YP_001727991.1	COG0252EJ
YP_001727997.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive
YP_001727998.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_001727999.1	COG0460E
YP_001728000.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_001728001.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_001728002.1	COG0212H
YP_001728004.1	COG0860M
YP_001728005.1	COG0282C; TIGR00016
YP_001728006.1	COG0488R
YP_001728007.1	COG0758LU
YP_001728008.1	COG0550L; TIGR01051
YP_001728010.1	COG3444G
YP_001728011.1	COG3715G
YP_001728012.1	COG3716G
YP_001728014.1	COG1670J
YP_001728015.1	COG1167KE
YP_001728016.1	COG0583K
YP_001728017.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001728019.1	COG0358L
YP_001728020.1	COG0568K
YP_001728021.1	COG4708S
YP_001728022.1	related to short-chain alcohol dehydrogenases; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_001728023.1	COG1573L
YP_001728024.1	COG3201H
YP_001728025.1	COG0471P
YP_001728026.1	COG0583K
YP_001728027.1	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate
YP_001728028.1	COG3493C
YP_001728029.1	COG0431R
YP_001728031.1	COG1063ER; similar to Zn-dependent dehydrogenase
YP_001728032.1	COG0386O
YP_001728033.1	COG2706G
YP_001728034.1	COG2826L
YP_001728035.1	COG3158P
YP_001728036.1	COG1316K
YP_001728037.1	COG0628R
YP_001728038.1	COG0117H; TIGR00326
YP_001728039.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_001728040.1	COG0807H
YP_001728041.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_001728042.1	COG0433R
YP_001728043.1	COG1477H
YP_001728044.1	COG0431R
YP_001728045.1	COG0431R
YP_001728046.1	COG0229O
YP_001728047.1	COG1680V
YP_001728048.1	COG2261S
YP_001728051.1	COG1302S
YP_001728052.1	COG1846K
YP_001728053.1	COG2249R
YP_001728054.1	COG1619V
YP_001728059.1	COG0454KR; similar to acetyltransferase
YP_001728060.1	COG2270R
YP_001728062.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001728063.1	related to diketogulonate reductase; COG0656R
YP_001728064.1	COG1233Q
YP_001728065.1	COG1562I
YP_001728066.1	COG4696S
YP_001728067.1	COG2261S
YP_001728068.1	COG1970M
YP_001728069.1	COG2188K
YP_001728070.1	COG2723G
YP_001728071.1	COG1455G
YP_001728072.1	COG1440G
YP_001728073.1	COG2211G
YP_001728074.1	COG0366G
YP_001728075.1	COG0446R
YP_001728076.1	COG1011R
YP_001728077.1	COG0664T
YP_001728078.1	COG3853P
YP_001728081.1	COG1249C
YP_001728082.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_001728083.1	COG1434S
YP_001728085.1	COG0584C
YP_001728086.1	COG0153G; TIGR00131
YP_001728087.1	catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism
YP_001728088.1	COG2211G
YP_001728089.1	COG3250G
YP_001728090.1	COG3250G
YP_001728091.1	COG2017G; similar to enzyme
YP_001728092.1	COG1609K
YP_001728093.1	COG0477GEPR
YP_001728094.1	COG1309K
YP_001728095.1	COG1309K
YP_001728100.1	COG0477GEPR
YP_001728101.1	COG1309K
YP_001728102.1	COG1670J
YP_001728103.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_001728104.1	COG3506S
YP_001728107.1	COG1670J
YP_001728108.1	COG0389L
YP_001728111.1	COG5263R
YP_001728119.1	COG1116P
YP_001728127.1	COG3942R
YP_001728135.1	COG1674D
YP_001728141.1	COG0038P
YP_001728142.1	COG0168P
YP_001728143.1	COG1808S
YP_001728144.1	COG2826L
YP_001728145.1	COG2826L
YP_001728148.1	COG3587V
YP_001728149.1	COG2189L
YP_001728154.1	COG1674D
YP_001728163.1	COG3942R
YP_001728176.1	COG0732V
YP_001728177.1	COG0286V; TIGR00497
YP_001728178.1	COG0610V
YP_001728179.1	COG1266R
YP_001728181.1	COG0454KR; similar to acetyltransferase
YP_001728182.1	COG1073R
YP_001728183.1	COG0393S
YP_001728186.1	COG0789K
YP_001728188.1	COG0463M
YP_001728189.1	COG0463M
YP_001728191.1	COG1209M; TIGR01207
YP_001728192.1	COG2173M
YP_001728193.1	COG1132V
YP_001728194.1	COG1846K
YP_001728195.1	COG1136V
YP_001728196.1	COG0577V
YP_001728198.1	COG1959K
YP_001728199.1	COG0702MG
YP_001728200.1	component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent
YP_001728201.1	COG0362G; TIGR00873
YP_001728202.1	COG2230M
YP_001728203.1	COG3866G
YP_001728205.1	COG1455G
YP_001728206.1	COG1455G
YP_001728207.1	COG2723G
YP_001728208.1	COG2723G
YP_001728209.1	COG3238S
YP_001728210.1	COG0011S
YP_001728211.1	COG0446R
YP_001728212.1	COG0664T
YP_001728213.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_001728214.1	COG1161R
YP_001728215.1	COG4479S
YP_001728216.1	COG4698S
YP_001728217.1	COG2755E
YP_001728218.1	catalyzes the release of the N-terminal amino acid from a tripeptide
YP_001728219.1	COG0327S
YP_001728220.1	COG2384R
YP_001728221.1	COG4948MR; similar to enzyme of enolase superfamily
YP_001728222.1	COG0596R
YP_001728223.1	COG1165H; TIGR00173
YP_001728224.1	COG1169HQ
YP_001728225.1	COG4720S
YP_001728226.1	COG0351H
YP_001728228.1	COG1284S
YP_001728229.1	COG0454KR; similar to acetyltransferase
YP_001728230.1	COG2183K
YP_001728231.1	COG3711K
YP_001728232.1	COG2723G
YP_001728233.1	COG2723G
YP_001728234.1	COG1263G
YP_001728235.1	COG0294H
YP_001728236.1	COG0127F
YP_001728237.1	COG0285H
YP_001728238.1	COG0302H
YP_001728239.1	COG0801H
YP_001728240.1	COG1539H; TIGR00525
YP_001728242.1	COG2017G; similar to enzyme
YP_001728243.1	COG4973L
YP_001728245.1	COG2848S
YP_001728246.1	ACT domain-containing protein
YP_001728247.1	COG3425I
YP_001728248.1	COG0488R
YP_001728250.1	COG1385S
YP_001728251.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_001728252.1	COG0604CR; similar to Zn-dependent oxidoreductase
YP_001728253.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_001728254.1	COG0697GER
YP_001728255.1	COG0673R
YP_001728256.1	COG0751J
YP_001728257.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001728258.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_001728259.1	Catalyzes the phosphorylation of UMP to UDP
YP_001728260.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_001728261.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_001728262.1	COG2827L
YP_001728263.1	COG4123R
YP_001728264.1	COG0204I
YP_001728266.1	Represses a number of genes involved in the response to DNA damage
YP_001728267.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001728268.1	COG0284F
YP_001728269.1	COG0167F
YP_001728270.1	COG0458EF
YP_001728271.1	COG0505EF
YP_001728272.1	COG0044F; similar to cyclic amidohydrolase
YP_001728273.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_001728274.1	COG0681U
YP_001728275.1	COG3679S
YP_001728276.1	COG0744M
YP_001728277.1	COG1438K
YP_001728278.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_001728280.1	COG0452H; TIGR00521
YP_001728281.1	COG0330O
YP_001728283.1	COG0474P
YP_001728284.1	COG0769M
YP_001728285.1	COG0475P
YP_001728286.1	COG0042J
YP_001728287.1	COG0285H
YP_001728288.1	COG0584C
YP_001728289.1	COG1653G
YP_001728290.1	COG0395G
YP_001728291.1	COG1175G
YP_001728292.1	COG3839G
YP_001728293.1	COG0111HE; similar to dehydrogenase
YP_001728294.1	COG3641R
YP_001728295.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_001728296.1	COG4470S
YP_001728297.1	COG0737F
YP_001728298.1	COG4186R
YP_001728300.1	COG0006E
YP_001728301.1	involved in the peptidyltransferase reaction during translation
YP_001728302.1	COG0261J; TIGR00061
YP_001728303.1	COG1309K
YP_001728313.1	COG2801L
YP_001728314.1	COG2963L
YP_001728315.1	COG5295UW
YP_001728317.1	COG5283S
YP_001728323.1	Orf116 gp
YP_001728326.1	COG0740OU
YP_001728328.1	COG4626R
YP_001728329.1	COG3747L
YP_001728330.1	COG2801L
YP_001728331.1	COG2963L
YP_001728333.1	COG0662G
YP_001728339.1	COG1226P
YP_001728341.1	COG3340E
YP_001728342.1	COG3247S
YP_001728343.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_001728344.1	COG4473U
YP_001728345.1	COG1131V
YP_001728346.1	COG0537FGR
YP_001728348.1	COG0760O
YP_001728349.1	COG3481R
YP_001728350.1	COG4717S
YP_001728351.1	COG0420L
YP_001728352.1	COG2706G
YP_001728354.1	COG2962R
YP_001728356.1	COG4748S
YP_001728357.1	COG1217T
YP_001728358.1	COG0483G
YP_001728359.1	COG4476S
YP_001728360.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_001728361.1	C-terminal Zn finger domain; COG0484O
YP_001728362.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_001728363.1	COG0576O
YP_001728364.1	COG1420K; TIGR00331
YP_001728365.1	COG0196H; TIGR00083
YP_001728366.1	COG0130J; TIGR00431
YP_001728368.1	COG0436E
YP_001728369.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_001728370.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_001728371.1	COG2740K
YP_001728372.1	COG0195K
YP_001728373.1	COG0779S
YP_001728374.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_001728375.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_001728376.1	COG1227C
YP_001728377.1	COG0188L; TIGR01061
YP_001728378.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001728379.1	COG0344S
YP_001728380.1	COG1490J; TIGR00256
YP_001728381.1	COG0317TK
YP_001728382.1	COG0477GEPR
YP_001728384.1	COG0458EF
YP_001728385.1	COG0505EF
YP_001728386.1	COG2065F
YP_001728387.1	COG0564J
YP_001728389.1	COG0328L
YP_001728390.1	COG1940KG
YP_001728391.1	COG1621G
YP_001728392.1	COG1263G
YP_001728393.1	COG1609K
YP_001728394.1	COG1942R
YP_001728395.1	COG1284S
YP_001728396.1	COG0174E; TIGR00653
YP_001728397.1	COG0789K
YP_001728398.1	COG0749L
YP_001728399.1	COG0670R
YP_001728400.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_001728401.1	COG0073R
YP_001728402.1	COG0775F
YP_001728404.1	COG0494LR
YP_001728405.1	COG1278K
YP_001728406.1	COG2252R
YP_001728407.1	COG1216R
YP_001728408.1	COG0615MI
YP_001728409.1	COG0463M
YP_001728410.1	COG0562M; TIGR00031
YP_001728413.1	COG2148M
YP_001728414.1	COG0024J; TIGR00500
YP_001728415.1	COG1940KG
YP_001728416.1	COG4483S
YP_001728417.1	COG0705R
YP_001728418.1	COG1074L
YP_001728419.1	COG3857L
YP_001728420.1	COG3557J
YP_001728422.1	COG2137R
YP_001728423.1	COG0289E; TIGR00036
YP_001728424.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_001728425.1	COG1473R
YP_001728426.1	COG2171E
YP_001728427.1	COG0019E; TIGR01048
YP_001728429.1	COG1488H
YP_001728431.1	COG0586S
YP_001728434.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_001728435.1	COG3142P
YP_001728436.1	similar to eukaryotic snRNP; COG1293K
YP_001728437.1	COG0477GEPR
YP_001728438.1	COG0078E; TIGR00658
YP_001728439.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_001728440.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_001728441.1	COG1316K
YP_001728442.1	COG2239P; TIGR00400
YP_001728443.1	COG0564J
YP_001728444.1	catalyzes the phosphorylation of NAD to NADP
YP_001728445.1	COG2357S
YP_001728448.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_001728449.1	COG0608L; TIGR00644
YP_001728450.1	COG1234R
YP_001728451.1	COG0225O
YP_001728452.1	COG1893H; TIGR00745
YP_001728453.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_001728454.1	COG1070G
YP_001728455.1	COG0477GEPR
YP_001728456.1	catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism
YP_001728457.1	COG1609K
YP_001728458.1	COG2966S
YP_001728459.1	COG0415L
YP_001728461.1	COG1309K
YP_001728462.1	Streptococcal; in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever
YP_001728463.1	COG1091M; TIGR01214
YP_001728464.1	COG1088M; TIGR01181
YP_001728465.1	COG1898M; similar to enzyme
YP_001728466.1	COG1209M; TIGR01207
YP_001728468.1	COG0438M
YP_001728469.1	COG0463M
YP_001728470.1	COG0463M
YP_001728473.1	COG0615MI
YP_001728474.1	COG3475M
YP_001728475.1	COG0438M
YP_001728476.1	COG2148M
YP_001728477.1	COG0489D
YP_001728478.1	COG3944M
YP_001728479.1	COG4464GM
YP_001728480.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_001728481.1	Essential for efficient processing of 16S rRNA
YP_001728482.1	COG5263R
YP_001728484.1	COG2801L
YP_001728485.1	COG2963L
YP_001728486.1	COG0350L
YP_001728487.1	COG1299G
YP_001728488.1	COG1105G
YP_001728489.1	COG1349KG
YP_001728491.1	COG0228J; TIGR00002
YP_001728492.1	COG3428S
YP_001728493.1	COG3402S
YP_001728495.1	COG1970M; TIGR00220
YP_001728496.1	COG1428F
YP_001728497.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_001728498.1	COG0809J; TIGR00113
YP_001728499.1	COG4186R
YP_001728500.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_001728501.1	COG0622R
YP_001728502.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_001728503.1	COG0796M; TIGR00067
YP_001728505.1	COG3966M
YP_001728506.1	COG0236IQ
YP_001728507.1	COG1696M
YP_001728508.1	COG1020Q
YP_001728509.1	COG1455G
YP_001728511.1	COG0513LKJ
YP_001728512.1	COG0618R
YP_001728513.1	COG0389L
YP_001728514.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_001728515.1	COG1109G
YP_001728516.1	COG0586S
YP_001728517.1	COG0366G
YP_001728518.1	COG0477GEPR
YP_001728519.1	COG0492O; TIGR01292
YP_001728520.1	COG1210M; TIGR01099
YP_001728521.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_001728522.1	COG1493T
YP_001728524.1	COG0704P
YP_001728525.1	COG1117P; TIGR00972
YP_001728526.1	COG1117P; TIGR00972
YP_001728527.1	COG0581P; TIGR00974
YP_001728528.1	COG0573P
YP_001728529.1	COG0226P
YP_001728530.1	COG5002T
YP_001728531.1	COG0226P
YP_001728532.1	COG0745TK
YP_001728533.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_001728534.1	COG0558I; TIGR00560
YP_001728535.1	COG1426S
YP_001728536.1	COG0612R
YP_001728537.1	COG0612R
YP_001728538.1	COG1502I; similar to enzyme
YP_001728539.1	COG0834ET
YP_001728540.1	COG1126E
YP_001728541.1	COG0765E
YP_001728542.1	COG2891M
YP_001728543.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_001728544.1	functions in MreBCD complex in some organisms
YP_001728546.1	COG0542O
YP_001728548.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_001728551.1	COG1215M
YP_001728554.1	COG5263R
YP_001728555.1	COG0079E; TIGR01141
YP_001728556.1	COG0561R
YP_001728558.1	COG0541U; TIGR00959
YP_001728559.1	COG2739S
YP_001728560.1	COG0552U; TIGR00064
YP_001728561.1	COG1196D
YP_001728562.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_001728563.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_001728564.1	COG4856S
YP_001728565.1	COG1624S
YP_001728566.1	COG0025P; TIGR00831
YP_001728567.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_001728568.1	COG0105F
YP_001728569.1	COG4807S
YP_001728570.1	COG0323L
YP_001728571.1	This protein performs the mismatch recognition step during the DNA repair process
YP_001728572.1	catalyzes branch migration in Holliday junction intermediates
YP_001728573.1	COG1012C
YP_001728578.1	COG1396K
YP_001728582.1	COG1476K
YP_001728583.1	COG4152R
YP_001728584.1	COG1668CP
YP_001728586.1	COG4176E
YP_001728587.1	COG4175E
YP_001728588.1	COG0490P
YP_001728589.1	COG1268R
YP_001728590.1	COG0190H
YP_001728591.1	COG2131F
YP_001728592.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_001728593.1	COG1670J
YP_001728594.1	COG1216R
YP_001728597.1	COG1887M
YP_001728598.1	COG1682GM
YP_001728599.1	COG1134GM
YP_001728600.1	COG0602O
YP_001728601.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_001728602.1	catalyzes the formation of 2-acetolactate from pyruvate in stationary phase
YP_001728603.1	COG0536R
YP_001728604.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_001728605.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_001728606.1	COG2265J; TIGR00479
YP_001728607.1	related to eukaryotic diacylglycerol kinase; similar to YegS from E. coli
YP_001728608.1	COG0064J; TIGR00133
YP_001728609.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001728610.1	COG0721J; TIGR00135
YP_001728611.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_001728612.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001728613.1	COG1466L
YP_001728614.1	COG2333R; TIGR00361
YP_001728615.1	COG1555L; similar to DNA-binding protein
YP_001728616.1	COG0038P
YP_001728619.1	COG1207M; TIGR01173
YP_001728620.1	COG0503F; similar to PRPP-binding protein
YP_001728621.1	COG1108P
YP_001728622.1	COG1121P
YP_001728624.1	COG4466S
YP_001728625.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_001728626.1	COG1658L
YP_001728627.1	COG0084L
YP_001728628.1	COG0781K
YP_001728629.1	COG1302S
YP_001728630.1	COG0231J; TIGR00038
YP_001728632.1	COG1611R
YP_001728633.1	COG5503S
YP_001728634.1	COG0595R
YP_001728635.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
YP_001728636.1	related to eukaryotic diacylglycerol kinase; COG1597IR
YP_001728638.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_001728640.1	COG4493S
YP_001728641.1	COG1295S
YP_001728642.1	COG1814S
YP_001728643.1	COG1814S
YP_001728644.1	COG0735P
YP_001728646.1	COG0474P
YP_001728648.1	COG3619S
YP_001728649.1	COG1464P
YP_001728650.1	COG1464P
YP_001728651.1	COG0624E; similar to deacylase
YP_001728652.1	COG1135P
YP_001728653.1	COG2011P
YP_001728654.1	COG2188K
YP_001728655.1	COG1820G; TIGR00221
YP_001728656.1	COG1267I
YP_001728657.1	COG1249C
YP_001728658.1	COG4721S
YP_001728659.1	COG1122P
YP_001728660.1	similar to transporter
YP_001728661.1	COG0819K
YP_001728662.1	COG5263R
YP_001728663.1	COG0477GEPR
YP_001728664.1	COG2837P
YP_001728665.1	COG0371C
YP_001728666.1	related to short-chain alcohol dehydrogenases; COG1028IQR
YP_001728667.1	COG1058R
YP_001728668.1	COG0149G
YP_001728669.1	COG2249R
YP_001728670.1	COG0433R
YP_001728671.1	COG1733K
YP_001728672.1	COG0550L
YP_001728676.1	COG1131V
YP_001728677.1	COG0637R
YP_001728678.1	COG1554G
YP_001728679.1	COG1263G
YP_001728680.1	COG2188K
YP_001728682.1	COG4487S
YP_001728683.1	COG0474P
YP_001728684.1	COG0531E
YP_001728685.1	COG0477GEPR
YP_001728687.1	COG5263R
YP_001728688.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_001728689.1	COG1281O
YP_001728690.1	COG0465O
YP_001728691.1	COG0634F; TIGR01203
YP_001728692.1	COG0037D
YP_001728694.1	implicated in the recycling of the 50S subunit (S4 paralog); COG1188J
YP_001728695.1	COG1197LK; TIGR00580
YP_001728696.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_001728697.1	FOG: CBS domain
YP_001728698.1	COG0366G
YP_001728699.1	COG2211G; similar to transporter
YP_001728701.1	COG1609K
YP_001728702.1	COG1575H
YP_001728703.1	COG2323S
YP_001728705.1	COG0716C
YP_001728706.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_001728707.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_001728708.1	COG1284S
YP_001728709.1	COG4687S
YP_001728710.1	COG3716G
YP_001728711.1	COG3715G
YP_001728712.1	COG3444G
YP_001728713.1	COG1482G; TIGR00218
YP_001728715.1	COG0438M
YP_001728718.1	COG1396K
YP_001728720.1	COG0778C
YP_001728721.1	COG4129S
YP_001728722.1	COG0561R
YP_001728723.1	COG2348V
YP_001728724.1	modulates transcription in response to the NADH/NAD(+) redox state
YP_001728725.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_001728726.1	COG0456R
YP_001728727.1	COG0456R
YP_001728728.1	COG1214O
YP_001728730.1	COG1595K
YP_001728731.1	COG1080G
YP_001728732.1	COG1925G
YP_001728733.1	COG0009J
YP_001728734.1	COG2890J
YP_001728735.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_001728736.1	COG1435F
YP_001728737.1	COG0769M
YP_001728738.1	COG3442R
YP_001728740.1	COG0531E
YP_001728741.1	COG2071R
YP_001728742.1	COG4166E
YP_001728743.1	COG0620E
YP_001728744.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_001728745.1	COG0620E
YP_001728746.1	COG0626E
YP_001728747.1	COG0626E
YP_001728748.1	COG1897E
YP_001728749.1	COG0526OC
YP_001728750.1	similar to lyase
YP_001728751.1	COG0738G; TIGR00885
YP_001728752.1	typically periplasmic, contains C-terminal PDZ domain; COG0265O
YP_001728753.1	COG0642T
YP_001728754.1	COG0745TK
YP_001728755.1	COG3376P
YP_001728757.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_001728758.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_001728759.1	COG0473CE; TIGR00169
YP_001728760.1	COG0119E
YP_001728761.1	COG2151R
YP_001728762.1	COG0719O
YP_001728763.1	involved in Fe-S cluster formation; COG0822C
YP_001728764.1	COG0520E
YP_001728765.1	COG0719O
YP_001728766.1	COG0396O
YP_001728768.1	COG0513LKJ
YP_001728769.1	COG0673R
YP_001728770.1	COG3757M
YP_001728771.1	COG2309E
YP_001728772.1	COG0345E; TIGR00112
YP_001728773.1	COG1428F
YP_001728774.1	COG1876M
YP_001728776.1	COG1476K
YP_001728777.1	COG1087M; TIGR01179
YP_001728778.1	COG3884I
YP_001728779.1	COG0313R
YP_001728780.1	COG0470L
YP_001728781.1	COG3870S
YP_001728782.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_001728784.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_001728785.1	COG2812L
YP_001728786.1	COG1418R
YP_001728787.1	COG0590FJ
YP_001728788.1	COG2813J
YP_001728789.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_001728790.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_001728791.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_001728792.1	binds directly to 23S ribosomal RNA
YP_001728793.1	COG0250K; TIGR00922
YP_001728794.1	TIGR00964
YP_001728795.1	COG1309K
YP_001728796.1	COG1511S
YP_001728797.1	COG1544J
YP_001728798.1	COG1040R
YP_001728799.1	COG4098L
YP_001728800.1	COG1739S
YP_001728801.1	COG0111HE; similar to dehydrogenase
YP_001728802.1	COG0524G
YP_001728806.1	COG1609K
YP_001728807.1	COG0248FP
YP_001728808.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_001728809.1	COG0248FP
YP_001728810.1	COG2818L
YP_001728811.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_001728813.1	COG0566J
YP_001728814.1	COG1939S
YP_001728815.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_001728816.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_001728817.1	COG0149G; TIGR00419
YP_001728819.1	COG1278K
YP_001728820.1	COG0588G
YP_001728821.1	COG0671I
YP_001728822.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
YP_001728823.1	COG1780F; TIGR00333
YP_001728824.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_001728825.1	COG0695O
YP_001728826.1	COG1253R; similar to protein containing CBS domains
YP_001728827.1	COG0406G
YP_001728828.1	COG2262R
YP_001728829.1	COG0103J
YP_001728830.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_001728831.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_001728832.1	COG0619P; similar to transporter
YP_001728833.1	COG1122P
YP_001728834.1	COG1122P
YP_001728835.1	COG1252C
YP_001728836.1	COG0142H
YP_001728837.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_001728838.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_001728839.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_001728840.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_001728841.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_001728842.1	COG0563F; similar to kinase
YP_001728843.1	COG0201U
YP_001728844.1	late assembly protein
YP_001728845.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_001728846.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_001728847.1	binds 5S rRNA along with protein L5 and L25
YP_001728848.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_001728849.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_001728850.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_001728851.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_001728852.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_001728853.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_001728854.1	one of the stabilizing components for the large ribosomal subunit
YP_001728855.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_001728856.1	COG0092J; TIGR01009
YP_001728857.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_001728858.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_001728859.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_001728860.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_001728861.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_001728862.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_001728863.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_001728864.1	COG0687E
YP_001728865.1	COG1177E
YP_001728866.1	COG1176E
YP_001728867.1	COG3842E
YP_001728868.1	COG2807P
YP_001728869.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_001728870.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_001728871.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_001728872.1	COG1989NOU
YP_001728873.1	COG0542O
YP_001728874.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_001728875.1	COG0653U; TIGR00963
YP_001728876.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001728877.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_001728878.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_001728880.1	COG0438M
YP_001728882.1	COG0477GEPR
YP_001728883.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
YP_001728884.1	COG3973R
YP_001728885.1	COG1902C
YP_001728887.1	related to metalloendopeptidases
YP_001728888.1	COG0737F
YP_001728889.1	COG3639P
YP_001728890.1	COG3639P
YP_001728891.1	COG3638P
YP_001728892.1	COG3221P
YP_001728893.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_001728894.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_001728895.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_001728896.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_001728897.1	COG0712C; TIGR01145
YP_001728898.1	COG0711C; TIGR01144
YP_001728899.1	TIGR01260
YP_001728900.1	COG0356C; TIGR01131
YP_001728901.1	COG2233F
YP_001728902.1	COG4108J; TIGR00503
YP_001728903.1	COG3338P
YP_001728904.1	COG0062S
YP_001728905.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_001728906.1	COG1272R
YP_001728907.1	COG1307S
YP_001728908.1	COG0239D
YP_001728910.1	COG0471P
YP_001728911.1	COG1053C
YP_001728912.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_001728913.1	COG0583K
YP_001728914.1	COG2461S
YP_001728915.1	COG1477H
YP_001728916.1	COG0431R
YP_001728918.1	COG2984R
YP_001728919.1	COG4120R
YP_001728920.1	COG1101R
YP_001728921.1	COG1113E; similar to permease
YP_001728922.1	COG0039C
YP_001728923.1	COG1972F
YP_001728924.1	COG1079R
YP_001728925.1	COG4603R
YP_001728926.1	COG3845R
YP_001728929.1	COG0168P
YP_001728930.1	COG0569P
YP_001728931.1	COG4814R
YP_001728932.1	COG1764O
YP_001728933.1	COG1695K
YP_001728934.1	COG0477GEPR
YP_001728937.1	COG1881R
YP_001728938.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_001728939.1	COG1364E; TIGR00120
YP_001728940.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_001728941.1	COG4992E
YP_001728942.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
YP_001728943.1	converts O-succinylbenzoate to O-succinylbenzoyl-CoA
YP_001728944.1	COG3682K
YP_001728945.1	COG2217P
YP_001728946.1	COG2217P
YP_001728947.1	COG4420S
YP_001728948.1	COG2610GE
YP_001728949.1	COG0580G; similar to permease (Major Intrinsic Protein Family)
YP_001728950.1	COG0564J
YP_001728952.1	COG0438M
YP_001728953.1	COG1368M; similar to alkaline phosphatase superfamily
YP_001728954.1	COG0454KR; similar to acetyltransferase
YP_001728958.1	COG0647G
YP_001728959.1	COG0477GEPR
YP_001728960.1	produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however
YP_001728961.1	COG0388R
YP_001728962.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_001728963.1	COG2050Q
YP_001728967.1	similar to acetyltransferase
YP_001728968.1	COG1309K
YP_001728969.1	COG0183I
YP_001728970.1	COG0318IQ
YP_001728971.1	COG0503F; similar to PRPP-binding protein
YP_001728972.1	COG0598P
YP_001728973.1	COG0454KR; similar to acetyltransferase
YP_001728974.1	COG0584C
YP_001728975.1	COG0706U
YP_001728976.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_001728977.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_001728978.1	COG0217S
YP_001728979.1	COG1187J; similar to pseudouridylate synthase