-- dump date 20111121_012913 -- class Genbank::CDS -- table cds_note -- id note NP_469348.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_469349.1 binds the polymerase to DNA and acts as a sliding clamp NP_469351.1 similar to Bacillus subtilis YaaA protein NP_469352.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_469355.1 similar to cardiolipin synthase NP_469356.1 similar to spermidine N1-acetyltransferase NP_469357.1 similar to mevalonate kinase NP_469358.1 similar to mevalonate diphosphate decarboxylase NP_469359.1 similar to mevalonate kinases NP_469363.1 highly similar to quinol oxidase aa3-600 chain IV NP_469365.1 lin0018 NP_469366.1 similar to transcriptional regulator (GntR family) NP_469367.1 similar to PTS system, fructose-specific IIA component NP_469368.1 similar to PTS system, fructose-specific IIB component NP_469369.1 similar to PTS system, fructose-specific IIC component NP_469370.1 similar to PTS system, mannose-specific IID component NP_469371.1 similar to phosphoheptose isomerase NP_469372.1 similar to Escherichia coli copper homeostasis protein CutC NP_469373.1 similar to PTS system, beta-glucosides specific enzyme IIABC NP_469374.1 similar to Escherichia coli microcin C7 self-immunity protein (MccF) NP_469375.1 lin0028 NP_469378.1 similar to xylose repressor NP_469379.1 similar to endoglucanase NP_469380.1 similar to PTS system, cellobiose-specific IIC component NP_469381.1 similar to Glucosamine--fructose-6-phosphate aminotransferase (C-terminal domain) NP_469382.1 similar to Escherichia coli DedA protein NP_469383.1 similar to arginine deiminase; catalyzes the degradation of arginine to citruline and ammonia NP_469384.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_469385.1 highly similar to single-strand binding protein (SSB) NP_469386.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_469387.1 lin0040 NP_469388.1 similar to Staphylococcus two-component sensor histidine kinase AgrB; essential for production of a quorum sensing autoinducing peptide NP_469389.1 lin0042 NP_469390.1 similar to sensor histidine kinase (AgrC from Staphylococcus) NP_469391.1 similar to 2-components response regulator protein (AgrA from Staphylococcus) NP_469392.1 highly similar to Bacillus subtilis YybT protein NP_469393.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_469394.1 highly similar to replicative DNA helicases; unwinds double stranded DNA NP_469395.1 highly similar to adenylosuccinate synthetase; catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_469396.1 similar to a small heat shock protein of Clostridium acetobutylicum NP_469397.1 similar to Bacillus subtilis YueB protein NP_469398.1 lin0051 NP_469399.1 similar to Bacillus subtilis YukD protein NP_469400.1 similar to Bacillus subtilis YukC protein NP_469401.1 highly similar to Bacillus subtilis YukA protein NP_469402.1 lin0055 NP_469403.1 lin0056 NP_469404.1 lin0057 NP_469405.1 lin0058 NP_469406.1 lin0059 NP_469407.1 lin0060 NP_469410.1 lin0064 NP_469411.1 lin0065 NP_469412.1 lin0066 NP_469413.1 similar to carboxyphosphonoenolpyruvate phosphonomutase NP_469414.1 similar to Escherichia coli Ada protein (O6-methylguanine-DNA methyltransferase) NP_469416.1 similar to phosphoglycerate dehydrogenase NP_469417.1 similar to integrase NP_469418.1 lin0072 NP_469419.1 similar to a putative repressor protein [Bacteriophage A118] NP_469420.1 highly similar to gp37 [Bacteriophage A118] NP_469421.1 highly similar to gp37-1 [Bacteriophage A118] NP_469422.1 lin0076 NP_469423.1 identical to gp40 [Bacteriophage A118] NP_469424.1 similar to protein gp41 [Bacteriophage A118] NP_469425.1 lin0079 NP_469426.1 similar to similar to anti-repressor [Bacteriophage A118] NP_469427.1 highly similar to gp43 [Bacteriophage A118] NP_469428.1 lin0082 NP_469429.1 highly similar to gp45 [Bacteriophage A118] NP_469430.1 highly similar to gp47 [Bacteriophage A118] NP_469431.1 putative recombinase [Bacteriophage A118] NP_469432.1 similar to protein gp49 NP_469433.1 similar to phage protein NP_469434.1 similar to site-specific DNA-methyltransferase NP_469435.1 similar to gp51 [Bacteriophage A118] NP_469436.1 lin0090 NP_469437.1 similar to phage proteins NP_469438.1 lin0092 NP_469439.1 lin0093 NP_469440.1 highly similar to gp55 [Bacteriophage A118] NP_469441.1 highly similar to gp59 [Bacteriophage A118] NP_469442.1 lin0096 NP_469443.1 similar to single-stranded DNA-binding protein NP_469445.1 similar to phage protein NP_469446.1 lin0100 NP_469447.1 Protein gp66 [Bacteriophage A118] NP_469448.1 lin0102 NP_469449.1 lin0103 NP_469450.1 highly similar to putative terminase small subunit [Bacteriophage A118] NP_469452.1 putative portal protein [Bacteriophage A118] NP_469453.1 Protein gp4 [Bacteriophage A118] NP_469454.1 putative scaffolding protein [Bacteriophage A118] NP_469455.1 highly similar to major capsid protein [Bacteriophage A118] NP_469456.1 Protein gp7 [Bacteriophage A118] NP_469457.1 Protein gp8 [Bacteriophage A118] NP_469458.1 Protein gp9 [Bacteriophage A118] NP_469459.1 Protein gp10 [Bacteriophage A118] NP_469460.1 Portein gp11 [Bacteriophage A118] NP_469461.1 major tail shaft protein [Bacteriophage A118] NP_469462.1 Protein gp14 [Bacteriophage A118] NP_469463.1 Protein gp15 [Bacteriophage A118] NP_469464.1 putative tape-measure [Bacteriophage A118] NP_469465.1 highly similar to gp17 [Bacteriophage A118] NP_469466.1 highly similar to gp18 [Bacteriophage A118] NP_469467.1 highly similar to gp19 [Bacteriophage A118] NP_469468.1 similar to gp20 [Bacteriophage A118] NP_469469.1 lin0124 NP_469470.1 lin0125 NP_469471.1 protein gp23 [Bacteriophage A118] NP_469472.1 holin [Bacteriophage A118] NP_469473.1 Bacteriophage A500 from Listeria NP_469474.1 lin0129 NP_469475.1 lin0130 NP_469476.1 lin0131 NP_469477.1 lin0132 NP_469478.1 lin0133 NP_469479.1 similar to ATP synthase C chain NP_469480.1 weakly similar to ATP synthase delta chain NP_469481.1 similar to ATP synthase alpha chain; produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit NP_469482.1 similar to ATP synthase gamma chain NP_469483.1 similar to ATP synthase beta chain; produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit NP_469484.1 similar to ATP synthase epsilon chain NP_469485.1 lin0140 NP_469487.1 lin0142 NP_469488.1 similar to PTS system mannose-specific, factor IIAB NP_469489.1 similar to PTS system mannose-specific, factor IIC NP_469490.1 similar to PTS system mannose-specific, factor IID NP_469491.1 lin0146 NP_469492.1 lin0147 NP_469494.1 similar to transcription regulator NP_469495.1 lin0150 NP_469496.1 similar to NADH oxidase NP_469497.1 lin0152 NP_469498.1 highly similar to chitinase B NP_469500.1 similar to ABC transporter, ATP-binding protein NP_469501.1 similar to ABC transporter, ATP-binding protein NP_469502.1 similar to transcriptional regulatory proteins, AraC family NP_469503.1 lin0158 NP_469504.1 weakly similar to transcription regulators, Fnr/Crp family NP_469505.1 similar to protein gp35 from Bacteriophage A118 NP_469506.1 similar to putative repressor C1 from lactococcal bacteriophage Tuc2009 NP_469507.1 similar to Antigen D NP_469508.1 similar to Antigen C NP_469511.1 lin0166 NP_469512.1 lin0167 NP_469513.1 similar to bacteriophage minor tail proteins NP_469514.1 similar to phage proteins NP_469515.1 similar to protein gp18 from Bacteriophage A118 NP_469516.1 lin0171 NP_469517.1 lin0172 NP_469518.1 lin0173 NP_469519.1 weakly similar to protein gp20 from Bacteriophage A118 NP_469520.1 similar to a protein from Bacteriophage phi-105 (ORF 45) NP_469521.1 similar to autolysin: N-acetylmuramoyl-L-alanine amidase NP_469522.1 similar to 5'-nucleotidase, putative peptidoglycan bound protein (LPXTG motif) NP_469524.1 similar to inosine monophosphate dehydrogenase; catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_469525.1 similar to Escherichia coli YjdI protein NP_469526.1 similar to Escherichia coli YjdJ protein NP_469527.1 similar to oligopeptide ABC transport system substrate-binding proteins NP_469528.1 similar to oligopeptide ABC transporter, permease protein NP_469529.1 similar to oligopeptide ABC transporter, permease protein NP_469530.1 lin0185 NP_469531.1 lin0186 NP_469532.1 lin0187 NP_469533.1 lin0188 NP_469534.1 lin0189 NP_469535.1 similar to oligopeptide ABC transporter-binding protein NP_469536.1 similar to a probable high-affinity zinc ABC transporter (Zn(II)-binding lipoprotein) NP_469537.1 similar to high-affinity zinc ABC transporter (ATP-binding protein) NP_469538.1 similar to high-affinity zinc ABC transporter (membrane protein) NP_469539.1 lin0194 NP_469540.1 similar to ATP dependent helicase NP_469542.1 similar to chloromuconate cycloisomerase ykfB of Bacillus subtilis NP_469544.1 some similarities to probable beta-lactamase NP_469545.1 similar to ABC transporter oligopeptide-binding protein NP_469546.1 similar to dipeptide ABC transporter NP_469549.1 lin0204 NP_469550.1 similar to Bacillus subtilis DNA polymerase III (delta' subunit); catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_469551.1 lin0206 NP_469552.1 similar to Bacillus subtilis YabA protein; in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA NP_469554.1 similar to Bacillus subtilis YazA protein NP_469556.1 similar to Bacillus subtilis transcription regulatory protein AbrB NP_469557.1 similar to a glucose uptake protein NP_469558.1 lin0213 NP_469560.1 similar to glucose uptake protein NP_469561.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_469562.1 similar to xylose repressor NP_469563.1 similar to sugar ABC transporters, permease proteins NP_469564.1 similar to sugar ABC transporter, permease protein NP_469565.1 similar to sugar ABC transporter, sugar-binding protein NP_469566.1 similar to alpha-xylosidase and alpha-glucosidase NP_469567.1 similar to alpha-glucosidase NP_469568.1 similar to oligo-1,6-glucosidase NP_469570.1 similar to Bacillus subtilis YabE protein NP_469571.1 similar to Bacillus subtilis YabF protein NP_469572.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_469573.1 highly similar to Bacillus subtilis Veg protein NP_469574.1 similar to Bacillus subtilis YabH protein; An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis NP_469575.1 similar to a putative phospho-beta-glucosidase NP_469576.1 similar to PurR, transcription repressor of purine operon of Bacillus subtilis NP_469577.1 lin0232 NP_469579.1 similar to membrane protein (putative ABC transporter component) NP_469580.1 similar to Bacillus subtilis SpoVG protein; stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus NP_469581.1 similar to Bacillus subtilis SpoVG protein; stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus NP_469582.1 highly similar to UDP-N-acetylglucosamine pyrophosphorylase; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_469583.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_469584.1 Uncharacterized lipoprotein Lin0239 precursor. NP_469586.1 lin0241 NP_469587.1 similar to L-lactate dehydrogenase; Converts (S)-lactate and NAD(+) to pyruvate and NADH NP_469588.1 similar to Bacillus subtilis general stress protein; the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_469589.1 lin0244 NP_469590.1 similar to peptidyl-tRNA hydrolase; Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_469592.1 conserved membrane-spanning protein NP_469593.1 highly similar to Bacillus subtilis YabO protein NP_469594.1 similar to Bacillus subtilis DivIC protein NP_469597.1 highly similar to cell division protein ftsH NP_469598.1 Type III pantothenate kinase; type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP NP_469599.1 33 kDa chaperonin (Heat shock protein 33 homolog) (HSP33); becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers NP_469600.1 highly similar to cysteine synthase NP_469601.1 highly similar to dihydropteroate synthases NP_469602.1 highly similar to dihydroneopterin aldolase NP_469603.1 similar to 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase NP_469605.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_469606.1 highly similar to transcription repressor of class III stress genes (CtsR) NP_469607.1 similar to Bacillus subtilis YacH protein NP_469608.1 similar to arginine kinase NP_469610.1 similar to DNA repair protein Sms; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_469611.1 highly similar to Bacillus subtilis YacL protein NP_469612.1 similar to nucleotidylyl transferase, pyrophosphorylase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_469613.1 similar to Bacillus subtilis YacN protein; catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_469614.1 highly similar to glutamyl-tRNA synthetase; Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_469615.1 similar to serine O-acetyltransferase NP_469616.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_469617.1 highly similar to Bacillus subtilis YazC protein NP_469618.1 similar to conserved hypothetical proteins like to Bacillus subtilis YacO protein NP_469619.1 similar to Bacillus subtilis Yacp protein NP_469620.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates NP_469621.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif NP_469622.1 highly similar to preprotein translocase subunit; forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_469623.1 Modulates Rho-dependent transcription termination NP_469624.1 lin0279 NP_469625.1 binds directly to 23S ribosomal RNA NP_469626.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_469627.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_469628.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_469630.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_469631.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_469633.1 similar to phospho-beta-glucosidase NP_469634.1 similar to succinyldiaminopimelate desuccinylase; dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica NP_469636.1 similar to transcriptional regulators NP_469637.1 similar to other proteins NP_469638.1 similar to phosphoglycerate mutase NP_469639.1 similar to transporter NP_469640.1 similar to internalin proteins NP_469641.1 lin0296 NP_469642.1 highly similar to phospho-beta-glucosidase NP_469643.1 conserved hypothetical protein similar to Bacillus subtilis YxeH protein NP_469644.1 lin0299 NP_469645.1 lin0300 NP_469648.1 similar to oxidoreductase NP_469649.1 similar to sugar ABC transporter, ATP-binding protein NP_469650.1 highly similar to anaerobic ribonucleoside-triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates NP_469651.1 highly similar to anaerobic ribonucleotide reductase activator protein NP_469652.1 similar to ABC transporters (ATP-binding protein) NP_469654.1 lin0309 NP_469656.1 similar to ABC transporter permease protein NP_469657.1 similar to ABC transporter (ATP-binding protein) NP_469659.1 similar to aminotransferase; produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however NP_469660.1 similar to two-component response regulator NP_469661.1 similar to two-component sensor histidine kinase NP_469662.1 similar to Bacillus subtilis YycH protein NP_469663.1 similar to Bacillus subtilis YycI protein NP_469664.1 conserved hypothetical protein similar to Bacillus subtilis YycJ protein NP_469665.1 similar to heat-shock protein htrA serine protease NP_469666.1 conserved hypothetical protein, highly similar to Bacillus subtilis YydA proteinYyd; SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA NP_469667.1 similar to transcription regulator LysR-gltR family NP_469668.1 similar to FMN-containing NADPH-linked nitro/flavin reductase NP_469669.1 lin0324 NP_469670.1 similar to transcriptional antiterminator (BglG family) NP_469671.1 similar to PTS beta-glucoside-specific enzyme IIC component NP_469672.1 similar to PTS beta-glucoside-specific enzyme IIB component NP_469673.1 similar to phospho-beta-glucosidase and phospho-beta-galactosidase NP_469674.1 similar to PTS beta-glucoside-specific enzyme IIA component NP_469675.1 lin0330 NP_469677.1 similar to putative permeases NP_469678.1 similar to low specificity L-allo-threonine aldolase NP_469679.1 lin0334 NP_469680.1 lin0335 NP_469681.1 lin0336 NP_469683.1 lin0338 NP_469685.1 similar to thiamin biosynthesis protein NP_469686.1 similar to hydroxyethylthiazole kinase (ThiM); catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP NP_469687.1 similar to phosphomethylpyrimidine kinase (ThiD) NP_469688.1 similar to thiamin-phosphate pyrophosphorylase (ThiE); Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate NP_469689.1 similar to phospho-beta-glucosidase NP_469690.1 lin0345 NP_469694.1 lin0349 NP_469695.1 similar to transcriptional regulators NP_469696.1 similar to transcriptional regulators NP_469697.1 similar to cell surface proteins (LPXTG motif) NP_469698.1 lin0353 NP_469699.1 similar to internalin, putative peptidoglycan bound protein (LPXTG motif) NP_469700.1 lin0355 NP_469701.1 lin0356 NP_469702.1 lin0357 NP_469703.1 weakly similar to inorganic pyrophosphatase NP_469704.1 lin0359 NP_469705.1 similar to transketolase NP_469706.1 similar to transaldolase; similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity NP_469707.1 similar to dehydrogenase/reductase NP_469708.1 similar to sugar-phosphate isomerase NP_469709.1 similar to triosephosphate isomerase NP_469710.1 similar to dihydroxyacetone kinase NP_469711.1 similar to dihydroxyacetone kinase NP_469712.1 lin0367 NP_469713.1 lin0368 NP_469715.1 highly similar to regulatory proteins (DeoR family) NP_469718.1 similar to fatty-acid--CoA ligase NP_469719.1 similar to Flavocytochrome C Fumarate Reductase chain A; Reduces fumarate to succinate in anaerobic bacterial respiration NP_469720.1 similar to oxidoreductase NP_469721.1 similar to PTS system, enzyme IIA component NP_469722.1 similar to PTS system, fructose-specific enzyme IIBC component NP_469723.1 similar to D-fructose-1,6-biphosphate aldolase NP_469724.1 similar to transcriptional regulator (DeoR family) NP_469725.1 similar to conserved hypothetical integral membrane protein NP_469726.1 similar to conserved hypothetical protein NP_469727.1 similar to Salmonella typhimurium peptidase E NP_469728.1 similar to transcription regulator NP_469729.1 similar to conserved hypothetical protein NP_469730.1 conserved hypothetical protein, putative lipoprotein NP_469731.1 conserved hypothetical protein similar to Bacillus subtilis YwbN protein NP_469732.1 similar to different proteins NP_469733.1 conserved hypothetical protein, highly similar to Bacillus subtilis YeeI protein NP_469735.1 similar to transcription regulator (GntR family) NP_469736.1 similar to beta-glucosidase NP_469737.1 similar to PTS betaglucoside-specific enzyme IIC component NP_469738.1 similar to PTS betaglucoside-specific enzyme IIB component NP_469739.1 lin0394 NP_469740.1 similar to putative transcription regulator NP_469741.1 lin0396 NP_469742.1 lin0397 NP_469743.1 lin0398 NP_469744.1 lin0399 NP_469745.1 similar to Bacillus subtilis transcription repressor of myo-inositol catabolism operon IolR NP_469746.1 highly similar to Bacillus subtilis methylmalonate-semialdehyde dehydrogenase IolA NP_469747.1 similar to Bacillus subtilis IolB protein NP_469748.1 similar to Bacillus subtilis IolC protein and to fructokinase NP_469749.1 similar to Bacillus subtilis IolD protein, to acetolactate synthase NP_469750.1 similar to Bacillus subtilis YhdG protein NP_469751.1 lin0406 NP_469753.1 similar to uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_469754.1 lin0409 NP_469755.1 highly similar to Bacillus subtilis YqfA protein NP_469756.1 lin0411 NP_469757.1 similar to L. monocytogenes extracellular P60 protein NP_469758.1 weakly similar to blasticidin S-acetyltransferase NP_469759.1 similar to 1-pyrroline-5-carboxylate reductase (ProC); catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_469761.1 similar to transcription regulator NP_469763.1 similar to ABC transporter, ATP-binding protein NP_469764.1 similar to ABC transporter, ATP-binding protein NP_469766.1 similar to phosphotransferase system enzyme IIA NP_469767.1 similar to fructose-specific phosphotransferase enzyme IIB NP_469768.1 similar to fructose-specific phosphotransferase enzyme IIC NP_469769.1 highly similar to E. col YbgG protein, a putative sugar hydrolase NP_469770.1 similar to transcriptional antiterminator (BglG family) NP_469771.1 lin0426 NP_469772.1 lin0427 NP_469773.1 similar to phosphate transport protein NP_469774.1 similar to Bacillus subtilis YyaH protein NP_469775.1 lin0430 NP_469776.1 lin0431 NP_469777.1 similar to phosphoenolpyruvate synthase; catalyzes the formation of phosphoenolpyruvate from pyruvate NP_469778.1 lin0433 NP_469779.1 lin0434 NP_469781.1 similar to endo-1,4-beta-xylanase NP_469782.1 similar to putative transcription regulator NP_469783.1 lin0438 NP_469784.1 lin0439 NP_469786.1 similar to rod shape-determining protein RodA NP_469787.1 part of sigC operon that is induced by temperature upshift NP_469788.1 similar to RNA polymerase ECF-type sigma factor; part of sigC operon induced by temperature upshift NP_469789.1 similar to Staphylococcus xylosus glucose uptake protein NP_469790.1 similar to transcription antiterminator BglG family NP_469791.1 similar to PTS fructose-specific enzyme IIA component NP_469792.1 similar to PTS fructose-specific enzyme IIC component NP_469793.1 similar to sugar hydrolase NP_469794.1 similar to transcriptional regulator (LysR family) NP_469795.1 similar to acetyltransferase NP_469796.1 similar to oxidoreductase NP_469797.1 lin0453 NP_469798.1 similar to cell wall-associated protein precursor wapA (Bacillus subtilis) NP_469799.1 lin0455 NP_469800.1 lin0456 NP_469804.1 weakly similar to a module of peptide synthetase NP_469805.1 similar to penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase) NP_469806.1 lin0462 NP_469807.1 similar to Bacillus subtilis transcription regulator LytR NP_469808.1 similar to putative transcription regulator NP_469809.1 conserved hypothetical protein, similar to yoaZ Bacillus subtilis NP_469810.1 lin0466 NP_469812.1 lin0468 NP_469815.1 conserved hypothetical protein similar to Bacillus subtilis YeaC NP_469817.1 similar to permeases NP_469819.1 similar to hydantoinase NP_469820.1 lin0476 NP_469821.1 lin0477 NP_469822.1 lin0478 NP_469823.1 lin0479 NP_469825.1 similar to putative transcriptional regulator NP_469826.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever NP_469827.1 similar to conserved hypothetical proteins, highly similar to Bacillus subtilis YloN protein; 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_469828.1 lin0485 NP_469830.1 lin0487; iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source NP_469831.1 lin0488 NP_469832.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_469833.1 lin0490 NP_469834.1 similar to transcriptional regulator (LysR family) NP_469835.1 similar to NADH:flavin oxidoreductase NP_469836.1 similar to shikimate 5-dehydrogenase; AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_469837.1 similar to 3-dehydroquinate dehydratase; catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis NP_469838.1 weakly similar to esterase NP_469839.1 similar to transmembrane protein NP_469840.1 similar to Bacillus subtilis YnzC protein NP_469841.1 similar to ribose 5-phosphate isomerase NP_469842.1 similar to ribulose-5-phosphate 3 epimerase NP_469843.1 similar to transaldolase NP_469844.1 similar to transcription antiterminator BglG family NP_469845.1 similar to putative sugar-phosphate isomerase NP_469846.1 similar to PTS fructose-specific enzyme IIA component NP_469847.1 lin0504 NP_469848.1 similar to ribulose-5-phosphate 3-epimerase NP_469849.1 similar to polyol (sorbitol) dehydrogenase NP_469850.1 similar to PTS system, Galactitol-specific IIB component NP_469851.1 similar to PTS system, Galactitol-specific IIC component NP_469852.1 similar to phosphoribosyl pyrophosphate synthetase NP_469853.1 lin0510 NP_469855.1 lin0512 NP_469856.1 weakly similar to transcription regulator NP_469857.1 similar to internalin protein, putative peptidoglycan bound protein (LPXTG motif) NP_469859.1 similar to Bacillus anthracis encapsulation protein CapA NP_469860.1 similar to phosphoglycerate mutase NP_469862.1 similar to multidrug resistance protein NP_469863.1 similar to transcription regulator NP_469864.1 similar to HsdR type IC restriction subunit NP_469865.1 similar to HsdM type IC modification subunit NP_469866.1 similar to specificity determinant HsdS NP_469867.1 similar to bacteriophage integrase NP_469868.1 similar to specificity determinant HsdS NP_469869.1 similar to 6-phospho-beta-glucosidase NP_469870.1 similar to transcription regulator NP_469871.1 similar to Bacillus subtilis YybC protein NP_469872.1 similar to putative sulfate transporter NP_469873.1 similar to transcription regulator (TipA from Streptomyces coelicolor) NP_469875.1 hypothetical secreted protein NP_469876.1 conserved hypothetical protein similar to putative glucosaminyltransferase NP_469877.1 lin0534 NP_469878.1 lin0535 NP_469879.1 lin0536 NP_469880.1 ACT domain-containing protein NP_469882.1 similar to transcription regulator (LacI family) NP_469883.1 similar to 6-phospho-beta-glucosidase NP_469884.1 similar to N-carbamyl-L-amino acid amidohydrolase; allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide NP_469885.1 similar to N-acyl-L-amino acid amidohydrolase NP_469886.1 similar to tagatose-1,6-diphosphate aldolase; catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources NP_469887.1 similar to penicillin-binding protein NP_469888.1 similar to ABC transporter (binding protein) NP_469889.1 similar to PTS system, glucitol/sorbitol-specific enzyme IIA component NP_469890.1 similar to PTS system, glucitol/sorbitol-specific enzyme IIBC component NP_469891.1 similar to PTS system, glucitol/sorbitol-specific enzyme II CII component NP_469892.1 lin0549 NP_469893.1 similar to putative NAD(P)-dependent oxidoreductase NP_469894.1 similar to Bacillus subtilis DeoR transcriptional regulator NP_469895.1 lin0552 NP_469896.1 similar to internalin protein NP_469898.1 lin0555 NP_469900.1 lin0557 NP_469901.1 similar to internalin protein NP_469903.1 lin0560 NP_469905.1 lin0562 NP_469906.1 similar to NADH-dependent butanol dehydrogenase NP_469907.1 similar to di-tripeptide transporter NP_469908.1 similar to phosphoglycerate mutase NP_469909.1 similar to phosphoglycerate mutase NP_469912.1 similar to NADP-specific glutamate dehydrogenase; converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer NP_469913.1 similar to phosphorybosil-AMP-cyclohydrolase (HisI2 protein); catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis NP_469914.1 similar to phosphoribosyl-AMP cyclohydrolase (HisI1 protein); PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers NP_469915.1 highly similar to cyclase HisF; catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase NP_469916.1 highly similar to phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide NP_469917.1 similar to amidotransferases; with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide NP_469918.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis NP_469919.1 highly similar to histidinol dehydrogenases; catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_469920.1 similar to ATP phosphoribosyltransferase; short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ NP_469921.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine NP_469922.1 similar histidinol phosphate phosphatase; catalyzes the formation of L-histidinol from L-histidinol phosphate NP_469923.1 similar to methyltransferase NP_469924.1 lin0581 NP_469926.1 similar to beta-glucosidase NP_469927.1 similar to transcription regulator GntR family NP_469928.1 hypothetical cell wall associated protein NP_469929.1 lin0586 NP_469932.1 weakly similar to carboxylesterase NP_469934.1 iap; p60; autolytic enzyme; can cleave bacterial peptidoglycan; secreted by SecA2 system NP_469935.1 similar to preprotein translocase SecA subunit; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins NP_469938.1 lin0595 NP_469940.1 similar to DNA photolyase NP_469941.1 lin0598 NP_469942.1 similar to a fusion of two types of conserved hypothetical proteinconserved hypothetical NP_469943.1 similar to unknown membrane proteins NP_469944.1 lin0601 NP_469945.1 similar to transport proteins (formate?) NP_469946.1 similar to homoserine O-acetyltransferase; Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine NP_469947.1 similar to O-acetylhomoserine sulfhydrylase NP_469949.1 similar to transcription regulator CRP/FNR family NP_469950.1 similar to proteins involved in biotin metabolism (BioY) NP_469952.1 lin0609 NP_469953.1 similar to cell surface protein NP_469954.1 weakly similar to transcription regulator NP_469955.1 lin0612 NP_469956.1 similar to Bacillus subtilis YvlA protein NP_469958.1 similar to transcription regulator MarR family NP_469959.1 similar to ABC transporter, ATP-binding protein NP_469960.1 similar to ABC transporter, ATP-binding protein NP_469961.1 similar to Escherichia coli phage shock protein E NP_469962.1 similar to internalin proteins, putative peptidoglycan bound protein (LPXTG motif) NP_469963.1 similar to acyl-carrier protein phosphodiesterase and NAD(P)H dehydrogenase; FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds NP_469964.1 similar to transcription regulator MarR family NP_469965.1 similar to oxidoreductase NP_469967.1 lin0624 NP_469969.1 lin0626 NP_469970.1 similar to protein kinase NP_469971.1 lin0628 NP_469972.1 lin0629 NP_469975.1 lin0632 NP_469977.1 lin0634 NP_469980.1 lin0637 NP_469981.1 lin0638 NP_469982.1 lin0639 NP_469984.1 weakly similar to methyltransferase NP_469985.1 similar to a transcription regulator (surface protein PAg negative regulator par) NP_469986.1 similar to oxidoreductase NP_469987.1 similar to heavy metal-transporting ATPase NP_469988.1 lin0645 NP_469989.1 similar to putative transaldolase NP_469991.1 similar to amino acid transporter NP_469993.1 lin0650 NP_469994.1 similar to membrane proteins NP_469995.1 similar to transcription regulators NP_469997.1 similar to transcription regulator NP_469999.1 lin0656 NP_470000.1 lin0657 NP_470001.1 similar to phosphoprotein phosphatases NP_470003.1 lin0660 NP_470006.1 similar to transcription regulator (Rgg type) NP_470007.1 similar to transposases NP_470008.1 highly similar to ORFA of Listeria seeligeri, (LPXTG motif) NP_470010.1 highly similar to phosphomethylpyrimidine kinase thiD NP_470012.1 similar to acetyl transferase NP_470013.1 lin0670 NP_470015.1 similar to ABC transporter (ATP-binding protein) NP_470016.1 similar to putative ABC transporter, permease protein NP_470017.1 similar to oxidoreductase NP_470018.1 lin0675 NP_470019.1 lin0676 NP_470021.1 lin0678 NP_470024.1 lin0681 NP_470025.1 lin0682 NP_470026.1 lin0683 NP_470027.1 similar to flagellar biosynthesic protein FliP; FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus NP_470028.1 similar to flagellar biosynthesis protein FliQ; with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus NP_470029.1 similar to flagellar biosynthetic protein FliR; FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus NP_470030.1 similar to flagellar biosynthetic protein flhB; membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export NP_470031.1 similar to flagella-associated protein flhA; membrane protein involved in the flagellar export apparatus NP_470032.1 similar to flagellar biosynthesis protein FlhF; Positive regulator of class III flagellar genes NP_470033.1 similar to flagellar hook-basal body protein FlgG; makes up the distal portion of the flagellar basal body rod NP_470034.1 similar to chemotactic methyltransferase CheR NP_470035.1 lin0692 NP_470036.1 similar to motility protein (flagellar motor rotation) MotA; With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine NP_470037.1 similar to motility protein (flagellar motor rotation) MotB NP_470038.1 lin0695 NP_470040.1 similar to CheA activity-modulating chemotaxis protein CheV NP_470041.1 structural flagella protein NP_470044.1 similar to flagellar motor switch protein fliY C-terminal part NP_470045.1 lin0702 NP_470046.1 lin0703 NP_470047.1 similar to flagellar hook assembly protein; acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod NP_470048.1 similar to flagellar hook protein FlgE; the hook connects flagellar basal body to the flagellar filament NP_470049.1 weakly similar to flagellar switch protein; One of three proteins involved in switching the direction of the flagellar rotation NP_470050.1 similar to flagellar switch protein FliM; with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation NP_470051.1 similar to flagellar motor switch protein fliY; One of three proteins involved in switching the direction of the flagellar rotation NP_470052.1 lin0709 NP_470053.1 lin0710 NP_470054.1 lin0711 NP_470055.1 lin0712 NP_470056.1 similar to flagellar hook-associated protein FlgK; with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook NP_470057.1 similar to flagellar hook-associated protein 3 FlgL; with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook NP_470058.1 similar to flagellar hook-associated protein 2 FliD; involved in flagellin assembly NP_470059.1 similar to hypothetical flagellar protein NP_470060.1 lin0717 NP_470061.1 similar to flagellar basal-body rod protein flgB; with FlgF and C makes up the proximal portion of the flagellar basal body rod NP_470062.1 similar to flagellar basal-body rod protein flgC; with FlgF and B makes up the proximal portion of the flagellar basal body rod NP_470063.1 similar to flagellar hook-basal body complex protein FliE; forms a junction between the M-ring and FlgB during flagella biosynthesis NP_470064.1 similar to flagellar basal-body M-ring protein fliF; the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod NP_470065.1 similar to flagellar motor switch protein fliG; One of three proteins involved in switching the direction of the flagellar rotation NP_470066.1 lin0723; binds to and inhibits the function of flagella specific ATPase FliI NP_470067.1 similar to H+-transporting ATP synthase alpha chain FliI, flagellar-specific, -; involved in type III protein export during flagellum assembly NP_470068.1 similar to transglycosylase NP_470069.1 lin0726 NP_470071.1 lin0728 NP_470073.1 similar to pyruvate oxidase; catalyzes the formation of acetyl phosphate from pyruvate NP_470074.1 similar to metyl-accepting chemotaxis protein NP_470075.1 similar to Bacillus subtilis YvpB protein NP_470077.1 similar to L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_470078.1 similar to riboflavin kinase / FAD synthase NP_470079.1 lin0736 NP_470080.1 lin0737 NP_470081.1 lin0738 NP_470085.1 similar to putative transcription regulator NP_470086.1 similar to transcriptional regulator (GntR family) NP_470087.1 similar to ABC transporter, ATP-binding protein NP_470088.1 lin0745 NP_470089.1 similar to ABC transporter, ATP-binding protein (truncated, N-terminal part) NP_470090.1 lin0748 NP_470092.1 Similar to ABC transporter (ATP-binding protein) NP_470094.1 lin0752 NP_470095.1 lin0753 NP_470096.1 lin0754 NP_470098.1 similar to ATP/GTP-binding protein NP_470100.1 similar to lipoate-protein ligase NP_470101.1 lin0759 NP_470102.1 similar to putative sugar ABC transporter, permease protein NP_470103.1 similar to ABC transporter, permease protein NP_470104.1 similar to sugar ABC transporter, periplasmic sugar-binding protein NP_470105.1 similar to alpha-1,6-mannanase NP_470106.1 similar to transcriptional regulator (LacI family) NP_470107.1 lin0765 NP_470108.1 similar to transcription regulator NP_470109.1 similar to alcohol dehydrogenase NP_470111.1 lin0769 NP_470112.1 similar to transcription regulator (repressor) NP_470113.1 lin0771 NP_470114.1 lin0772 NP_470115.1 lin0773 NP_470116.1 similar to mannose-specific phosphotransferase system (PTS) component IID; hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel NP_470117.1 similar to mannose-specific phosphotransferase system (PTS) component IIC NP_470118.1 similar to mannose-specific phosphotransferase system (PTS) component IIB NP_470119.1 similar to mannose-specific phosphotransferase system (PTS) component IIA NP_470120.1 similar to transcriptional regulator (NifA/NtrC family) NP_470121.1 similar to acyl-carrier protein phosphodiesterase and to NAD(P)H dehydrogenase NP_470122.1 similar to amino acid transporter NP_470123.1 lin0781 NP_470125.1 similar to transcription regulator (EbsC from Enterococcus faecalis) NP_470126.1 lin0784 NP_470127.1 similar to conserved hypothetical protein NP_470128.1 similar to conserved hypothetical protein NP_470129.1 similar to Bacillus subtilis YwnB protein NP_470132.1 lin0790 NP_470133.1 similar to lysine-specific permease NP_470134.1 lin0792 NP_470135.1 similar to Bacillus subtilis YqkB protein NP_470136.1 weakly similar to GTP-pyrophosphokinase NP_470137.1 similar to putative Na+/H+ antiporter NP_470138.1 similar to transcription regulator NP_470139.1 similar to spermidine/putrescine ABC transporter, ATP-binding protein NP_470140.1 similar to spermidine/putrescine ABC transporter, permease protein NP_470141.1 similar to spermidine/putrescine ABC transporter, permease protein NP_470142.1 similar to spermidine/putrescine-binding protein NP_470143.1 similar to two-component response regulators NP_470144.1 similar to two-component sensor histidine kinases NP_470147.1 similar to oxidoreductase NP_470148.1 similar to transcriptional regulator, MerR family NP_470149.1 similar to carbonic anhydrase NP_470150.1 lin0808 NP_470151.1 similar to fructokinases NP_470152.1 similar to oxidoreductases NP_470153.1 similar to transcription regulators NP_470154.1 similar to Bacillus subtilis regulatory protein PaiA NP_470155.1 similar to Escherichia coli PhnB protein NP_470156.1 similar to cation transporting ATPase NP_470157.1 lin0815 NP_470158.1 some similarity to acatyltransferases NP_470159.1 lin0817 NP_470160.1 similar to transcriptional regulators NP_470161.1 similar to oxydoreductases NP_470162.1 lin0820 NP_470163.1 similar to 3-hydroxy-3-methylglutaryl-coenzyme a reductase NP_470164.1 similar to transport protein (Truncated, N-terminal part) NP_470165.1 similar to transport protein (truncated, C-terminal part) NP_470166.1 highly similar to pyruvate-flavodoxin oxidoreductase NP_470167.1 highly similar to fructose-1,6-bisphosphatase NP_470168.1 lin0826 NP_470169.1 similar to transposase NP_470170.1 similar to Bacillus subtilis YrkR protein NP_470171.1 similar to ABC transporter (ATP binding protein) NP_470172.1 similar to Tetracycline resistance protein NP_470173.1 lin0831 NP_470174.1 similar to cation (calcium) transporting ATPase NP_470175.1 lin0833 NP_470176.1 some similarities to hypothetical proteins NP_470177.1 lin0835 NP_470178.1 similar to Bacillus subtilis protein YsdA NP_470180.1 similar to Bacillus subtilis YxjH and YxjG proteins NP_470181.1 similar to excinuclease ABC, chain C (UvrC) NP_470182.1 similar to Glutamine ABC transporter (binding and transport protein) NP_470183.1 similar to amino acid ABC transporter, ATP-binding protein NP_470184.1 similar to amidases; catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia NP_470186.1 lin0844 NP_470187.1 similar to transcription regulator TetR/AcrR family NP_470188.1 similar to Escherichia coli SugE protein (transmembrane chaperone) NP_470189.1 similar to Escherichia coli SugE protein (transmembrane chaperone) NP_470190.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_470192.1 similar to carboxylesterase NP_470193.1 similar to transcription regulator lacI family NP_470194.1 similar to putative sugar ABC transporter, periplasmic sugar-binding protein NP_470195.1 similar to sugar ABC transporter, permease protein NP_470196.1 similar to sugar ABC transporter, permease protein - NP_470197.1 similar to oligo-1,6-glucosidase NP_470198.1 lin0856 NP_470199.1 lin0857 NP_470200.1 similar to phosphomannomutase NP_470201.1 similar to ATP-dependent RNA helicase NP_470202.1 lin0860 NP_470203.1 lin0861 NP_470204.1 lin0862 NP_470205.1 lin0863 NP_470206.1 similar to transcription regulator NP_470208.1 similar to ABC transporters, ATP-binding protein homologue NP_470209.1 lin0867 NP_470210.1 lin0868 NP_470211.1 similar to Bacillus subtilis YtcD protein NP_470212.1 similar to antibiotic resistance protein NP_470213.1 Similar to transcriptional regulator (antiterminator) NP_470214.1 similar to PTS system enzyme IIA component NP_470215.1 similar to PTS system, beta-glucoside enzyme IIB component NP_470216.1 similar to PTS system, Lichenan-specific enzyme IIC component NP_470217.1 similar to Bacillus subtilis NagB protein (glucosamine-6-phosphate isomerase) NP_470218.1 similar to oxidoreductases NP_470220.1 similar to wall associated protein precursor (LPXTG motif) NP_470221.1 lin0880 NP_470222.1 similar to Bacillus subtilis YdbS protein NP_470223.1 similar to Bacillus subtilis YbtB protein NP_470224.1 similar to protoporphyrinogen IX and coproporphyrinogen III oxidase (HemY); catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX NP_470225.1 similar to holo-acyl-carrier protein synthase; Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_470226.1 similar to alanine racemase NP_470227.1 similar to Bacillus subtilis YdcD protein NP_470228.1 similar to Bacillus subtilis YdcE protein NP_470229.1 highly similar to positive regulator of sigma-B activity NP_470230.1 highly similar to negative regulation of sigma-B activity NP_470231.1 highly similar to positive regulation of sigma-B activity NP_470232.1 highly similar to serine phosphatase RsbU NP_470234.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme NP_470235.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase NP_470237.1 similar to transport proteins NP_470239.1 similar to Bacillus subtilis YdcK protein NP_470240.1 lin0899 NP_470241.1 similar to PTS system, cellobiose-specific IIC component NP_470242.1 similar to transcription regulator (GntR family) NP_470245.1 lin0905 NP_470246.1 similar to glutathione Reductase; catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense NP_470247.1 similar to phosphoglycerate mutase NP_470248.1 similar to membrane proteins NP_470249.1 similar to transcription regulator, GntR family NP_470250.1 lin0910 NP_470251.1 lin0911 NP_470252.1 similar to transporters (formate) NP_470253.1 similar to succinate semialdehyde dehydrogenase NP_470254.1 similar to PTS system, IIB component NP_470255.1 similar to phosphotransferase system enzyme IIC (truncated, N-terminal end) NP_470256.1 similar to phosphotransferase system enzyme IIA NP_470257.1 similar to beta-glucosidase NP_470258.1 similar to transcription antiterminator BglG family NP_470259.1 similar to ABC transporter ATP-binding protein (antibiotic resistance) NP_470260.1 similar to Bacillus subtilis YcgR protein NP_470261.1 similar to Bacillus subtilis YcgQ protein NP_470262.1 similar to pantothenate kinase; catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_470263.1 similar to ABC transporter, ATP-binding protein NP_470265.1 similar to transcription regulator (TetR/AcrR family) NP_470267.1 similar to 3-methyladenine DNA glycosylase; responsible for recognizing base lesions in the genome and initiating base excision DNA repair NP_470268.1 similar to sortase NP_470269.1 conserved hypothetical protein, similar to Bacillus subtilis YhfI protein NP_470270.1 similar to lipoate protein ligase A NP_470272.1 similar to Bacillus subtilis YhbA protein NP_470273.1 similar to Nitroflavin-reductase NP_470274.1 lin0936 NP_470275.1 similar to protein-tyrosine-phosphatase NP_470276.1 lin0938 NP_470277.1 lin0939 NP_470278.1 similar to heat shock protein HtpG NP_470280.1 similar to Bacillus subtilis YneR protein NP_470281.1 similar to C-terminal part of Bacillus subtilis ComEC protein and to ComEA NP_470282.1 lin0945 NP_470283.1 hypothetical transport protein NP_470284.1 similar to transcription regulator NP_470286.1 lin0949 NP_470287.1 lin0950 NP_470288.1 lin0951 NP_470289.1 lin0952 NP_470290.1 lin0953 NP_470291.1 lin0954 NP_470292.1 similar to N-acetylglucosamine-6P-phosphate deacetylase (EC 3.5.1.25) NP_470293.1 similar to glucosamine-6-Phoasphate isomerase (EC 5.3.1.10) NP_470294.1 similar to transcription regulator (GntR family) NP_470295.1 similar to undacaprenyl-phosphate N-acetylglucosaminyltransferase NP_470296.1 similar to proteases NP_470297.1 similar to proteases NP_470299.1 similar to putative heat shock protein HtpX, Listeria epitope LemB; putative metalloprotease NP_470300.1 similar to Bacillus subtilis YjbH protein NP_470301.1 similar to Bacillus subtilis YjbK protein NP_470302.1 lin0965 NP_470303.1 similar to Bacillus subtilis YjbM protein NP_470304.1 Probable inorganic polyphosphate/ATP-NAD kinase 1; catalyzes the phosphorylation of NAD to NADP NP_470305.1 similar to ribosomal large subunit pseudouridine synthetase NP_470306.1 similar to enoyl- acyl-carrier protein reductase; Catalyzes a key regulatory step in fatty acid biosynthesis NP_470308.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid NP_470310.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid NP_470311.1 similar to ribose 5-phosphate isomerase; Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway NP_470312.1 similar to Bacillus subtilis YjcF protein NP_470313.1 similar to Bacillus subtilis YjcH protein NP_470314.1 similar to branched-chain amino acid aminotransferase; catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_470315.1 similar to daunorubicin resistance ATP-binding proteins NP_470316.1 similar to ABC transporter transmembrane component NP_470317.1 similar to efflux transporter NP_470318.1 similar to glucanase and peptidase NP_470319.1 similar to glutathione peroxidase NP_470320.1 weakly similar to two-component response regulator NP_470321.1 lin0984 NP_470322.1 similar to antibiotic ABC transporter, ATP-binding protein NP_470323.1 similar to Streptococcus agalactiae CylB protein NP_470324.1 similar to peptide chain release factor 3 (RF-3); stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein NP_470325.1 similar to regulatory proteins (MarR family) NP_470329.1 similar to Na+-transporting ATP synthase subunit J NP_470330.1 lin0993 NP_470331.1 similar to Bacillus subtilis YkrP protein NP_470332.1 similar to methylated-DNA-protein-cystein methyltransferase NP_470334.1 similar to hypothetical protein NP_470335.1 lin0998 NP_470336.1 similar to phytoene dehydrogenase NP_470337.1 similar to Bacillus subtilis protein YkvS NP_470341.1 similar to 3-hydroxyisobutyrate dehydrogenase (Bacillus subtilis YkwC protein) NP_470342.1 similar to aminotransferases (to Bacillus subtilis PatA protein) NP_470343.1 lin1006 NP_470344.1 similar to Bacillus subtilis YkuJ protein NP_470345.1 similar to Bacillus subtilis YkuL protein NP_470346.1 similar to transcription regulator (LysR family). NP_470347.1 similar to tetrahydrodipicolinate succinylase NP_470348.1 similar to N-acyl-L-amino acid amidohydrolases NP_470349.1 similar to conserved hypothetical proteins like to Bacillus subtilis YkuT protein NP_470350.1 highly similar to glycine betaine ABC transporter (ATP-binding protein) NP_470351.1 highly similar to glycine betaine ABC transporters (permease) NP_470352.1 highly similar to glycine betaine ABC transporters (glycine betaine-binding protein) NP_470353.1 similar to phosphotransferase system glucose-specific enzyme IIA NP_470354.1 similar to Escherichia coli copper homeostasis protein CutC NP_470355.1 similar to Bacillus subtilis YitL protein NP_470356.1 similar to Bacillus subtilis YvqF protein NP_470357.1 similar to two-component sensor histidine kinase in particular Bacillus subtilis YvqE protein NP_470358.1 similar to two-component response regulator, in particular Bacillus subtilis YvqC protein NP_470359.1 similar to a bacterial K(+)-uptake system NP_470360.1 lin1023 NP_470361.1 lin1024 NP_470362.1 similar to Bacillus subtilis LytR protein NP_470363.1 similar to conserved hypothetical proteins (in particular Bacillus subtilis YkqC) NP_470364.1 similar to Bacillus subtilis YkzG protein NP_470366.1 highly similar to Bacillus subtilis YoaT protein NP_470367.1 weakly similar to molybdopterin-guanine dinucleotide biosynthesis protein A NP_470368.1 similar to ABC transporter, ATP-binding protein NP_470369.1 similar to molybdenum ABC transporters (permease) NP_470370.1 similar to molybdate ABC transporter binding protein NP_470371.1 similar to molybdopterin biosynthesis protein moeA NP_470372.1 similar to molybdopterin-guanine dinucleotide biosynthesis MobB NP_470373.1 similar to molybdopterin converting factor, subunit 2 NP_470374.1 similar to molybdopterin converting factor (subunit 1). NP_470375.1 similar to molybdenum cofactor biosynthesis protein C; MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis NP_470376.1 similar to molybdenum cofactor biosynthesis protein A; together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z NP_470377.1 similar to molybdenum cofactor biosynthesis protein B NP_470378.1 similar to molybdopterin biosynthesis protein MoeB NP_470379.1 similar to Bacillus subtilis YdfE protein NP_470380.1 similar to formylmethionine deformylase and to Bacillus subtilis YkrB protein; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_470381.1 highly similar to pyruvate dehydrogenase (E1 alpha subunit) NP_470382.1 highly similar to pyruvate dehydrogenase (E1 beta subunit) NP_470383.1 highly similar to pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit); Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA NP_470384.1 highly similar to dihydrolipoamide dehydrogenase, E3 subunit of pyruvate dehydrogenase complex; E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_470385.1 lin1048 NP_470386.1 similar to L-lactate dehydrogenase NP_470387.1 similar to Bacillus subtilis YktA protein NP_470388.1 lin1051 NP_470389.1 similar to membrane and transport proteins NP_470390.1 similar to Bacillus subtilis YktB protein NP_470391.1 similar to extragenic suppressor protein SuhB and to myo-inositol-1(or 4)-monophosphatase NP_470392.1 similar to GTP-binding elongation factor NP_470393.1 lin1056 NP_470394.1 similar to Bacillus subtilis YlaI protein NP_470395.1 similar to Bacillus subtilis YlaN protein; depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; putative ligand binding protein NP_470396.1 similar to cell-division protein RodA and FtsW NP_470397.1 highly similar to pyruvate carboxylase; biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate NP_470398.1 similar to metal binding protein (ABC transporter) NP_470399.1 highly similar to teichoic acid translocation permease protein TagG NP_470400.1 similar to teichoic acid translocation ATP-binding protein TagH (ABC transporter) NP_470401.1 similar to autolysin (amidase) NP_470402.1 lin1065 NP_470403.1 similar to dolichol phosphate mannose synthase NP_470404.1 lin1067 NP_470405.1 similar to hypothetical protein 3 (capsulation locus) of Haemophilus influenzae NP_470406.1 lin1069 NP_470407.1 similar to putative UDP-glucose pyrophosphorylases NP_470408.1 similar to CDP-ribitol pyrophosphorylase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_470409.1 similar to glucitol dehydrogenase NP_470410.1 similar to galactosamine-containing minor teichoic acid biosynthesis protein GgaA NP_470411.1 similar to Bacillus subtilis TagF protein (probable CDPglycerol glycerophosphotransferase) NP_470412.1 similar to teichoic acid biosynthesis protein B precursor NP_470413.1 highly similar to glycerol-3-phosphate cytidylyltransferase (gct), CDP-glycerol pyrophosphorylase (teichoic acid biosynthesis protein D) NP_470414.1 conserved hypothetical protein, similar to Bacillus subtilis YueK protein; catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate NP_470415.1 similar to NH(3)-dependent NAD(+) synthetases, nitrogen regulatory protein; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_470416.1 lin1079 NP_470417.1 similar to PTS system, cellobiose-specific IIB component (cel A) NP_470418.1 highly similar to GMP synthetase; contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_470419.1 lin1082 NP_470420.1 lin1083 NP_470421.1 lin1084 NP_470422.1 lin1085 NP_470423.1 lin1086 NP_470424.1 lin1087 NP_470425.1 lin1088 NP_470426.1 lin1089 NP_470427.1 lin1090 NP_470428.1 lin1091 NP_470429.1 similar to Escherichia coli YjaB protein NP_470430.1 lin1093 NP_470431.1 lin1094 NP_470433.1 similar to transcription regulators NP_470434.1 similar to ABC transporters, ATP-binding proteins NP_470435.1 similar to ABC transporters, ATP-binding proteins NP_470436.1 lin1099 NP_470437.1 lin1100 NP_470438.1 similar to internalin, putative peptidoglycan bound protein (LPXTG motif) NP_470439.1 lin1102 NP_470440.1 similar to ATP-dependent Clp protease proteolytic component; hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_470441.1 lin1104 NP_470442.1 similar to uroporphyrin-III C-methyltransferase NP_470443.1 similar to Salmonella enterica PduS protein NP_470444.1 similar to Salmonella enterica PduT protein NP_470445.1 similar to Salmonelle enterica PduU protein NP_470446.1 similar to Salmonella enterica PduV protein NP_470447.1 lin1110 NP_470448.1 similar to bifunctional cobalamin biosynthesis protein CopB, (cobinamide kinase; cobinamide phosphatase guanylyltransferase) NP_470449.1 highly similar to cobalamin (5'-phosphatase) synthetase NP_470450.1 similar to alpha-ribazole-5'-phosphatase NP_470452.1 similar to Salmonella typhimurium PduA protein NP_470453.1 similar to Salmonella typhimurium PduB protein NP_470454.1 highly similar to propanediol dehydratase, alpha subunit NP_470455.1 similar to diol dehydrase (diol dehydratase) gamma subunit NP_470456.1 similar to diol dehydrase (diol dehydratase) gamma subunit (pddC) NP_470457.1 similar to diol dehydratase-reactivating factor large subunit NP_470458.1 similar to diol dehydratase-reactivating factor small chain NP_470459.1 similar to Salmonella enterica PduK protein NP_470460.1 similar to carboxysome structural protein NP_470461.1 similar to Salmonella enterica PduL protein NP_470462.1 similar to ethanolamine utilization protein EutJ NP_470463.1 lin1126 NP_470464.1 similar to carbon dioxide concentrating mechanism protein NP_470466.1 similar to ethanolamine utilization protein EutE NP_470467.1 similar to NADPH-dependent butanol dehydrogenase NP_470468.1 similar to glycerol uptake facilitator protein NP_470469.1 similar to acetate kinase NP_470470.1 similar to Salmonella typhimurium CobD protein and to histidinol-phosphate aminotransferase; cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase NP_470471.1 similar to Salmonella enterica PduX protein NP_470472.1 similar to NADPH-dependent butanol dehydrogenase NP_470473.1 similar to similar to two-component response regulator NP_470474.1 similar to two-component sensor histidine kinase NP_470475.1 similar to ethanolamine utilization protein EutA (putative chaperonin) NP_470476.1 similar to ethanolamine ammonia-lyase, heavy chain NP_470477.1 similar to ethanolamine ammonia-lyase, light chain; catalyzes the formation of acetaldehyde from ethanolamine NP_470478.1 similar to putative carboxysome structural protein (eutL) NP_470479.1 similar to putative carboxysome structural protein NP_470480.1 similar to acetaldehyde dehydrogenase / alcohol dehydrogenase NP_470481.1 similar to putative carboxysome structural protein NP_470482.1 similar to cobalamin adenosyl transferase NP_470483.1 similar to Salmonella enterica PduL protein NP_470484.1 lin1147 NP_470485.1 similar to carbon dioxide concentrating mechanism protein NP_470486.1 similar to Salmonella enterica PduT protein NP_470487.1 similar to ethanolamine utilization protein EutH - Escherichia coli NP_470488.1 similar to ethanolamine utilization protein EutQ NP_470489.1 similar to transcriptional regulator NP_470490.1 lin1153 NP_470491.1 similar to cobyrinic acid a,c-diamide synthase; responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid NP_470492.1 similar to cobalamine synthesis protein CbiB; CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group NP_470493.1 similar to precorrin isomerase; catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin NP_470494.1 similar to cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A NP_470495.1 similar to precorrin methylase; catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a NP_470496.1 similar to precorrin decarbocylase; catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W; decarboxylating NP_470497.1 similar to precorrin-3 methylase NP_470498.1 similar to cobalamin biosynthesis protein G CbiG; catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3 NP_470499.1 similar to precorrin methylase; catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine NP_470500.1 similar to cobalamin biosynthesis J protein CbiJ NP_470501.1 similar uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase NP_470502.1 similar to anaerobic Cobalt Chelatase In Cobalamin Biosynthesis NP_470503.1 similar to S-adenosyl-methionine: precorrin-2 methyltransferase; catalyzes the formation of precorrin-3A from precorrin-2 NP_470504.2 similar to cobalamin biosynthesis protein M; catalyzes the ATP-dependent transport of cobalt NP_470505.1 similar to putative cobalt transport protein CbiN; periplasmic cobalt binding component of the cobalt transport system NP_470506.1 similar to cobalt transport protein Q NP_470507.1 similar to cobalt transport ATP-binding protein CbiO NP_470508.1 similar to cobyric acid synthase CbiP; catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation NP_470514.1 lin1177 NP_470515.1 similar to N-acetylmuramoyl-L-alanine amidase (autolysin) NP_470516.1 similar to N-acetylmuramoyl-L-alanine amidase (autolysin) NP_470517.1 similar to endo-1,4-beta-glucanase and to aminopeptidase NP_470518.1 similar to rRNA methylase NP_470519.1 lin1182 NP_470521.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_470522.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_470523.1 similar to ABC transporter, ATP-binding proteins NP_470524.1 similar to different proteins NP_470525.1 similar to transcriptional regulator (MarR family). NP_470526.1 similar to transporter, (to Bacillus subtilis YdgH protein) NP_470527.1 similar to uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_470528.1 similar to Bacillus subtilis ribonuclease HIII; An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids NP_470529.1 similar to Bacillus subtilis YshA protein NP_470530.1 similar to Bacillus subtilis YshB protein NP_470531.1 similar to DNA polymerase beta, to Bacillus subtilis YshC protein NP_470532.1 similar to MutS protein (MutS2); MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange NP_470534.1 highly similar to excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_470535.1 similar to aspartokinase II alpha subunit; catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation NP_470536.1 similar to Bacillus subtilis YslB protein NP_470537.1 similar to glutamate racemase; converts L-glutamate to D-glutamate, a component of peptidoglycan NP_470538.1 similar to ribonuclease PH; RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs NP_470539.1 Nucleoside-triphosphatase; hydrolyzes non-standard nucleotides such as xanthine and inosine NP_470540.1 conserved hypothetical protein, similar to Bacillus subtilis YsnB protein NP_470541.1 similar to internalin proteins (LPXTG motif) NP_470542.1 lin1205 NP_470543.1 similar to Bacillus subtilis YdeI protein NP_470544.1 lin1207 NP_470545.1 weakly similar to phosphoglycerate mutase 1 NP_470546.1 lin1209 NP_470547.1 lin1210 NP_470548.1 lin1211 NP_470549.1 lin1212 NP_470550.1 lin1213 NP_470551.1 similar to ATP-dependent RNA helicase (DEAD motif) NP_470552.1 weakly similar to 8-oxo-dGTPase (mutT) NP_470553.1 lin1216 NP_470554.1 similar to antibiotic resistance protein NP_470555.1 similar to regulator of the Fnr CRP family (including PrfA) NP_470556.1 similar to Bacillus subtilis YxkD protein NP_470557.1 lin1220 NP_470558.1 similar to transcription regulator GntR family NP_470559.1 similar to alpha,alpha-phosphotrehalase NP_470560.1 similar to PTS system trehalose specific enzyme IIBC NP_470561.1 lin1224 NP_470562.1 lin1225 NP_470563.1 lin1226 NP_470564.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_470565.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_470566.1 lin1229 NP_470567.1 similar to transcriptional regulator (phage-related) NP_470568.1 similar to site-specific recombinase for integration and excision [bacteriophage phi-105] NP_470570.1 similar to bacteriophage phi-105 ORF2 protein NP_470571.1 similar to immunity repressor [bacteriophage phi-105] NP_470572.1 similar to transcription regulator NP_470573.1 lin1236 NP_470574.1 lin1237 NP_470575.1 lin1238 NP_470576.1 lin1239 NP_470577.1 lin1240 NP_470578.1 similar to bacteriophage protein NP_470579.1 some similarities to phage related proteins NP_470580.1 similar to hypothetical protein 44 - Staphylococcus aureus phage phi PVL NP_470581.1 lin1244 NP_470582.1 similarities Staphylococcus aureus prophage phiPV83 NP_470583.1 lin1246 NP_470584.1 lin1247 NP_470585.1 similar to hypothetical protein, Staphylococcus aureus phage phi PVL NP_470586.1 lin1249 NP_470587.1 lin1250 NP_470588.1 lin1251 NP_470589.1 lin1252 NP_470590.1 lin1253 NP_470591.1 similar to phage intagrase proteins NP_470592.1 lin1255 NP_470593.1 lin1256 NP_470594.1 lin1257 NP_470595.1 lin1258 NP_470596.1 similar to protein gp66 [Bacteriophage A118] NP_470597.1 similar to probable antirepressor - Bacillus subtilis phage SPBc2 NP_470598.1 lin1261 NP_470599.1 lin1262 NP_470600.1 lin1263 NP_470601.1 lin1264 NP_470602.1 lin1265 NP_470603.1 similar to phage protein NP_470604.1 similar to a Bacillus subtilis PBSX phage protein NP_470605.1 similar to a Bacillus subtilis PBSX phage protein NP_470607.1 similar to a Bacillus subtilis PBSX phage protein NP_470608.1 similar to a Bacillus subtilis PBSX phage protein NP_470609.1 lin1272 NP_470611.1 similar to a Bacillus subtilis PBSX phage protein NP_470612.1 similar to a Bacillus subtilis PBSX phage protein NP_470613.1 similar to a Bacillus subtilis PBSX phage protein NP_470614.1 lin1277 NP_470615.1 similar to a Bacillus subtilis PBSX phage protein NP_470616.1 similar to a Bacillus subtilis PBSX phage protein NP_470617.1 similar to a Bacillus subtilis PBSX phage protein NP_470618.1 similar to phage proteins NP_470619.1 similar to a Bacillus subtilis PBSX prophage protein NP_470620.1 similar to a Bacillus subtilis PBSX prophage protein NP_470621.1 similar to a Bacillus subtilis PBSX prophage protein NP_470622.1 similar to a Bacillus subtilis PBSX prophage protein NP_470623.1 similar to a Bacillus subtilis PBSX prophage protein NP_470624.1 similar to a Bacillus subtilis PBSX prophage protein NP_470626.1 lin1290 NP_470627.1 lin1291 NP_470628.1 lin1292 NP_470629.1 lin1293 NP_470630.1 lin1294 NP_470631.1 similar to holin NP_470632.1 similar to hypothetical protein - phage SPP1 NP_470633.1 similar to Portein gp28 [Bacteriophage A118] NP_470634.1 lin1298 NP_470635.1 lin1299 NP_470636.1 lin1300 NP_470637.1 lin1301 NP_470638.1 lin1302 NP_470639.1 lin1303 NP_470640.1 weakly similar to oligopeptide ABC transporter AppA (binding protein) NP_470641.1 lin1305 NP_470642.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_470643.1 binds and unfolds substrates as part of the ClpXP protease NP_470644.1 similar to type-I signal peptidase NP_470645.1 similar to signal peptidase I NP_470646.1 similar to signal peptidase I NP_470647.1 conserved hypothetical protein similar to Bacillus subtilis YlqF protein; essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) NP_470648.1 similar to ribonuclease H rnh; RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_470649.1 similar to polypeptide deformylase, similar to Bacillus subtilis Smf protein NP_470650.1 highly similar to DNA topoisomerase I TopA; catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_470651.1 similar glucose inhibited division protein A; TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine NP_470652.1 similar to integrase/recombinase NP_470653.1 highly similar to beta-type subunit of the 20S proteasome; heat shock protein involved in degradation of misfolded proteins NP_470654.1 highly similar to ATP-dependent Clp protease-like proteins; heat shock protein involved in degradation of misfolded proteins NP_470655.1 highly similar to Bacillus subtilis CodY protein; CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor NP_470656.1 similar to Bacillus subtilis YneP protein NP_470657.1 similar to Bacillus subtilis YneQ protein NP_470658.1 similar to Lactococcus lactis LacX protein NP_470659.1 conserved hypothetical protein, similar to Bacillus subtilis YneS protein NP_470660.1 conserved hypothetical protein, similar to Bacillus subtilis YneT protein NP_470661.1 highly similar to DNA gyrase-like protein (subunit B); decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_470662.1 highly similar to DNA gyrase-like protein (subunit A); decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_470663.1 S-ribosylhomocysteine lyase; catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 NP_470665.1 similar to acyltransferase (to Bacillus subtilis YrhL protein) NP_470666.1 similar to glycerophosphodiester phosphodiesterase NP_470667.1 similar to glycerol 3 phosphate dehydrogenase NP_470668.1 similar to tRNA isopentenylpyrophosphate transferase; IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_470669.1 similar to host factor-1 protein NP_470670.1 conserved hypothetical protein similar to Bacillus subtilis YnbA protein NP_470671.1 similar to aluminum resistance protein and to Bacillus subtilis YnbB protein (hypothetical) NP_470672.1 similar to glutamine synthetase repressor NP_470673.1 highly similar to glutamine synthetases NP_470674.1 similar to arsenic efflux pump protein NP_470676.1 highly similar to SOS response regulator lexA, transcription repressor protein; Represses a number of genes involved in the response to DNA damage NP_470677.1 similar to Bacillus subtilis YneA protein NP_470678.1 similar to Bacillus subtilis YnzC protein NP_470679.1 highly similar to transketolase NP_470680.1 highly similar to Bacillus subtilis YneF protein NP_470681.1 weakly similar to arginine N-methyltransferases NP_470682.1 similar to Escherichia coli YbdM protein NP_470683.1 similar to Escherichia coli YbdN protein NP_470684.1 lin1348 NP_470685.1 lin1349 NP_470686.1 highly similar to uridylate kinases; Catalyzes the phosphorylation of UMP to UDP NP_470687.1 highly similar to ribosome recycling factors; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_470688.1 similar to undecaprenyl diphosphate synthase; catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_470689.1 similar to phosphatidate cytidylyltransferase (CDP-diglyceride synthase) NP_470690.1 similar to deoxyxylulose 5-phosphate reductoisomerase; catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_470691.1 Putative zinc metalloprotease Lin1355 NP_470692.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_470693.1 highly similar to DNA polymerase III (alpha subunit); catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity NP_470694.1 conserved hypothetical protein, similar to Bacillus subtilis YlxS protein; in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins NP_470695.1 highly similar to N utilization substance protein A (NusA protein); modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_470696.1 similar to Bacillus subtilis YlxR protein NP_470697.1 conserved hypothetical protein, similar to Bacillus subtilis YlxQ protein NP_470698.1 highly similar to translation initiation factor IF-2; Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_470699.1 conserved hypothetical protein similar to Bacillus subtilis YlxP protein NP_470700.1 highly similar to ribosome-binding factor A; associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_470701.1 highly similar to tRNA pseudouridine 55 synthase; catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_470702.1 highly similar to riboflavin kinase and FAD synthase NP_470703.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_470705.1 Probable GTPase engC 2 NP_470706.1 similar to Bacillus subtilis YqzC protein NP_470707.1 similar to Bacillus subtilis YqzD protein NP_470708.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_470709.1 similar to 5-formyltetrahydrofolate cyclo-ligase NP_470710.1 similar to Bacillus subtilis yqgP NP_470711.1 similar to Bacillus subtilis yqgQ NP_470712.1 similar to glucose kinase NP_470713.1 similar to Bacillus subtilis YqgU protein NP_470714.1 weakly similar to Bacillus subtilis comG operon protein 7 (comGG) NP_470715.1 similar to Bacillus subtilis comG operon protein 6 NP_470716.1 similar to comG operon protein 5 (comGE) NP_470717.1 similar to comG operon protein 4 (comGD) NP_470718.1 similar to Bacillus subtilis comG operon protein 3 NP_470719.1 similar to Bacillus subtilis comG operon protein 2 NP_470720.1 similar to Bacillus subtilis comG operon protein 1 NP_470721.1 similar to aminomethyltransferase; catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein NP_470722.1 similar to glycine dehydrogenase (decarboxylating) subunit 1; acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein NP_470723.1 similar to glycine dehydrogenase (decarboxylating) subunit 2; acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein NP_470724.1 lin1388 NP_470725.1 lin1389 NP_470726.1 similar to Bacillus subtilis YqhQ protein NP_470727.1 similar to aminopeptidase P NP_470728.1 highly similar to elongation factor P (EF-P); Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_470729.1 similar to acetyl-CoA carboxylase subunit (biotin carboxyl carrier subunit) NP_470730.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_470731.1 similar to Bacillus subtilis YqhY protein NP_470732.1 similar to transcription termination protein (NusB); Regulates rRNA biosynthesis by transcriptional antitermination NP_470733.1 highly similar to methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_470734.1 similar to exodeoxyribonuclease VII (large subunit); bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_470735.1 similar to exodeoxyribonuclease small subunit; catalyzes the bidirectional exonucleolytic cleavage of DNA NP_470736.1 similar to geranyltranstransferase NP_470737.1 similar to cold shock protein NP_470738.1 similar to D-1-deoxyxylulose 5-phosphate synthase; catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_470740.1 similar to arginine repressor; regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes NP_470742.1 similar to phosphotransbutyrylase NP_470743.1 similar to branched-chain fatty-acid kinase; catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate NP_470744.1 similar to branched-chain alpha-keto acid dehydrogenase E3 subunit; E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_470745.1 similar to branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisovalerate dehydrogenase alpha subunit) NP_470746.1 similar to branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisovalerate dehydrogenase beta subunit) NP_470747.1 similar to branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase) NP_470748.1 similar to aminotripeptidase NP_470749.1 similar to 6-phosphogluconate dehydrogenase; catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_470752.1 similar to Bacillus subtilis SpoIIIJ protein; involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site NP_470753.1 lin1417 NP_470754.1 lin1418; catalyzes the hydrolysis of acylphosphate NP_470755.1 lin1419 NP_470756.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate NP_470759.1 similar to DNA translocase NP_470760.1 similar to pyrroline-5-carboxylate reductase; catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_470762.1 similar to sugar ABC transporter, ATP-binding protein NP_470763.1 similar to ABC transporter (permease proteins) NP_470764.1 similar to sugar ABC transporter, permease protein NP_470765.1 similar to putative proteases NP_470766.1 similar to putative protease NP_470767.1 similar to 3-ketoacyl-acyl carrier protein reductase NP_470769.1 similar to phosphatidylglycerophosphate synthase NP_470770.1 similar to competence-damage inducible protein CinA NP_470771.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_470772.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP NP_470773.1 similar to N-acetyltransferase NP_470775.1 similar to Bacillus subtilis YmcA protein NP_470776.1 This protein performs the mismatch recognition step during the DNA repair process NP_470777.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex NP_470778.1 similar to putative anti-terminator regulatory protein NP_470782.1 similar to multidrug-efflux transporter NP_470783.1 lin1447 NP_470784.1 lin1448 NP_470786.1 lin1450 NP_470787.1 lin1451 NP_470788.1 lin1452 NP_470789.1 similar to Acetyl-CoA:acetyltransferase NP_470790.1 similar to hydroxy-3-methylglutaryl coenzyme A synthase NP_470791.1 lin1455 NP_470792.1 highly similar to Bacillus subtilis YxiO protein NP_470793.1 weakly similar to pyrophosphatase NP_470795.1 weakly similar to UDP-N-acetylglucosaminyl-3-enolpyruvate reductase; catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_470796.1 similar to glycine betaine/carnitine/choline ABC transporter (ATP-binding protein) NP_470797.1 similar to glycine betaine/carnitine/choline ABC transporter (membrane protein) NP_470798.1 lin1462 NP_470799.1 similar to manganese transport proteins NRAMP NP_470800.1 similar to betaine/carnitine/choline ABC transporter (membrane p) NP_470801.1 similar to glycine betaine/carnitine/choline ABC transporter (osmoprotectant-binding protein) NP_470802.1 similar to glycine betaine/carnitine/choline ABC transporter (membrane protein) NP_470803.1 similar to glycine betaine/carnitine/choline ABC transporter (ATP-binding protein) NP_470806.1 similar to ABC transporter (ATP-binding protein) NP_470807.1 lin1471 NP_470808.1 similar to glutathione reductase NP_470810.1 similar to dihydrodipicolinate synthase; catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_470811.1 similar to aspartokinase I (alpha and beta subunits); catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive NP_470812.1 similar to aspartate-semialdehyde dehydrogenase NP_470813.1 similar to penicillin-binding protein NP_470816.1 similar to transport proteins NP_470817.1 lin1481 NP_470818.1 similar to protein secretion PrsA (post-translocation molecular chaperone) NP_470822.1 Probable manganese-dependent inorganic pyrophosphatase; catalyzes the hydrolysis of pyrophosphate to phosphate NP_470823.1 similar to endonuclease IV; Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues NP_470824.1 similar to ATP-dependent RNA helicase, DEAD-box family (deaD) NP_470827.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium NP_470831.1 similar to glycyl-tRNA synthetase beta chain; glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_470832.1 similar to glycyl-tRNA synthetase alpha chain; glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_470833.1 similar to Bacillus subtilis RecO protein involved in DNA repair and homologous recombination; involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_470834.1 lin1498 NP_470835.1 similar to GTP binding proteins; Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_470836.1 similar to cytidine deaminase NP_470837.1 similar to diacylglycerol kinase NP_470840.1 similar to phosphate starvation induced protein PhoH NP_470842.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA NP_470843.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_470844.1 similar to ribosomal protein L11 methyltransferase; methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype NP_470845.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_470846.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_470847.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_470848.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NP_470849.1 highly similar to coproporphyrinogen III oxidase; catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_470850.1 highly similar to GTP-binding protein LepA; binds to the ribosome on the universally-conserved alpha-sarcin loop NP_470851.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_470852.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA NP_470853.1 similar to putative integral membrane protein ComEC specifically required for DNA uptake but not for binding NP_470854.1 similar to Bacillus subtilis ComEB protein NP_470855.1 similar to integral membrane protein ComEA NP_470857.1 lin1521 NP_470859.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_470861.1 similar to shikimate 5-dehydrogenase (AroD) NP_470862.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis NP_470864.1 similar to oligopeptidase NP_470865.1 similar to 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NP_470867.1 similar to transcription elongation factor GreA; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_470868.1 similar to Uridine kinase; functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor NP_470869.1 similar to O-methyltransferase NP_470873.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_470874.1 lin1538 NP_470875.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_470876.1 similar to ABC transporter, ATP-binding protein NP_470877.1 similar to transporter NP_470878.1 similar to two-component response regulators NP_470879.1 similar to two-component sensor histidine kinase NP_470880.1 similar to exodeoxyribonuclease V NP_470883.1 similar to putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_470884.1 similar to iron-sulfur cofactor synthesis protein NP_470887.1 similar to ammonium transporter NrgA NP_470888.1 similar to nitrogen regulatory PII protein NP_470889.1 lin1553 NP_470890.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_470891.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_470892.1 similar to N-acetylmuramoyl-L-alanine amidase NP_470893.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_470894.1 similar to (p)ppGpp synthetase NP_470895.1 similar to adenine phosphoribosyltransferase; catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_470896.1 similar to single-stranded-DNA-specific exonuclease (RecJ) NP_470898.1 similar to protein-export membrane protein SecDF; part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_470901.1 similar to tRNA-guanine transglycosylase Tgt; Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) NP_470902.1 similar to S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step NP_470903.1 highly similar to Holliday junction DNA helicase RuvB; promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_470904.1 highly similar to Holliday junction DNA helicase (ruvA); plays an essential role in ATP-dependent branch migration of the Holliday junction NP_470905.1 similar to L-lactate dehydrogenase NP_470907.1 similar to prephenate dehydratase PheA; catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis NP_470908.1 conserved GTP binding protein; essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_470909.1 similar to glycerol kinase; Converts glycerol and ADP to glycerol-3-phosphate and ADP NP_470910.1 similar to glycerol uptake facilitator NP_470911.1 involved in the peptidyltransferase reaction during translation NP_470914.1 similar to ribonuclease G NP_470915.1 highly similar to cell division inhibitor (septum placement) protein MinD NP_470916.1 similar to cell-division inhibition (septum placement) protein MinC; blocks the formation of polar Z-ring septums NP_470917.1 similar to cell-shape determining protein MreD NP_470918.1 similar to cell-shape determining protein MreC; in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall NP_470919.1 similar to cell-shape determining protein MreB; functions in MreBCD complex in some organisms NP_470920.1 similar to DNA repair protein RadC; Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase NP_470921.1 similar to Bacillus subtilis late competence protein ComC (type IV prepilin peptidase) NP_470922.1 similar to Folyl-polyglutamate synthetase NP_470923.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_470924.1 highly similar to glutamate-1-semialdehyde 2,1-aminotransferases; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_470925.1 highly similar to delta-aminolevulinic acid dehydratases (porphobilinogen synthase); catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_470926.1 similar to uroporphyrinogen III cosynthase (HemD); catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis NP_470927.1 highly similar to porphobilinogen deaminases (hydroxymethylbilane synthase); transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_470928.1 highly similar to glutamyl-tRNA reductase; catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_470929.1 Probable GTP-binding protein engB; binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential NP_470930.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_470931.1 Primosomal protein that may act to load helicase DnaC during DNA replication NP_470934.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_470935.1 highly similar to formamidopyrimidine-DNA glycosylases; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases NP_470936.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_470937.1 highly similar to isocitrate dehyrogenases; Converts isocitrate to alpha ketoglutarate NP_470938.1 highly similar to citrate synthase subunit II; catalyzes the formation of citrate from acetyl-CoA and oxaloacetate NP_470940.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein NP_470941.1 highly similar to pyruvate kinases; catalyzes the formation of phosphoenolpyruvate from pyruvate NP_470942.1 lin1606; catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_470943.1 highly similar to acetyl CoA carboxylase (alpha subunit); catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein NP_470944.1 highly similar to acetyl-CoA carboxylase beta subunit; catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits NP_470945.1 highly similar to DNA polymerase III (alpha subunit) DnaE NP_470948.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins NP_470949.1 similar to X-Pro dipeptidase NP_470950.1 similar to alanine dehydrogenase NP_470952.1 highly similar to acetate kinase; AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_470953.1 weakly similar to site specific DNA-methyltransferase NP_470954.1 similar to a protein encoded by Th916 NP_470955.1 lin1619 NP_470956.1 similar to putative iron-sulfur flavoprotein NP_470957.1 similar to ketoacyl reductases NP_470958.1 similar to transcriptional regulator (MerR family) NP_470959.1 similar to site-specific recombinase tnpX - Clostridium perfringens transposon Tn4451 (N terminal part) NP_470960.1 similar to site-specific recombinase tnpX - Clostridium perfringens transposon Tn4451 NP_470961.1 similar to thiol peroxidases; antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein NP_470963.1 similar to proteases NP_470964.1 catalyzes the phosphorylation of NAD to NADP NP_470965.1 highly similar to ornithine carbamoyltransferase; catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation NP_470966.1 highly similar to N-acetylornithine aminotransferase NP_470967.1 highly similar to N-acetylglutamate 5-phosphotransferase; catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_470968.1 highly similar to ornithine acetyltransferase and amino-acid acetyltransferases; bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate NP_470969.1 similar to N-acetylglutamate gamma-semialdehyde dehydrogenases; catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_470970.1 similar to thiamin biosynthesis protein ThiI; Required for the synthesis of the thiazole moiety NP_470971.1 similar to iron-sulfur cofactor synthesis protein nifS NP_470972.1 similar to Bacillus subtilis negative regulator of FtsZ ring formation (EzrA); acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation NP_470974.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_470977.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate NP_470978.1 similar to general stress protein NP_470980.1 similar to aminopeptidase NP_470981.1 similar to 2-cys peroxiredoxin NP_470982.1 similar to UDP-N-acetyl muramate-alanine ligases; Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_470983.1 similar to DNA translocase NP_470984.1 similar phenylalanyl-tRNA synthetase (beta subunit) NP_470986.1 similar to thioredoxin NP_470988.1 similar to aminopeptidase NP_470992.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_470994.1 similar to multidrug-efflux transporter NP_470995.1 similar to transcription regulator MarR family NP_470997.1 similar to Xaa-His dipeptidase; divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases NP_470998.1 weakly similar to Escherichia coli MutT protein (dGTP pyrophosphohydrolase NP_471001.1 similar to putative transporters NP_471002.1 similar to putative transporters NP_471003.1 lin1667 NP_471004.1 highly similar to tryptophan synthase (alpha subunit); catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_471005.1 highly similar to tryptophan synthase (beta subunit); catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_471006.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis NP_471007.1 highly similar to indol-3-glycerol phosphate synthases; involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water NP_471008.1 highly similar to anthranilate phosphoribosyltransferase; Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate NP_471009.1 highly similar to anthranilate synthase beta subunit; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity NP_471010.1 highly similar to anthranilate synthase alpha subunit; with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine NP_471011.1 similar to Alcohol-acetaldehyde dehydrogenase NP_471013.1 similar to similar to ABC transporter (ATP-binding protein) NP_471014.1 similar to membrane proteins NP_471016.1 similar to dna-3-methyladenine glycosidase NP_471017.1 lin1681 NP_471018.1 highly similar to aconitate hydratases; Catalyzes the conversion of citrate to isocitrate NP_471019.1 similar to putative sigma factor regulator NP_471020.1 lin1684 NP_471021.1 similar to SNF2-type helicase NP_471022.1 similar to ATP-dependent dsDNA exonuclease SbcC NP_471023.1 similar to putative exonucleases SbcD NP_471024.1 similar to 1-acylglycerol-3-phosphate O-acyltransferases NP_471025.1 lin1689 NP_471027.1 similar to ABC transporter (ATP-binding protein) NP_471028.1 similar to ABC transporter (ATP-binding protein) NP_471032.1 lin1696 NP_471033.1 protein gp30 [Bacteriophage A118] NP_471034.1 protein gp29 [Bacteriophage A118] NP_471035.1 Portein gp28 [Bacteriophage A118] NP_471036.1 similar to N-acetylmuramoyl-L-alanine amidase (N-terminal part) and to L-alanoyl-D-glutamate peptidase (C-terminal part) NP_471037.1 lin1701 NP_471038.1 similar to holin from bacteriophage NP_471039.1 lin1703 NP_471040.1 lin1704 NP_471041.1 lin1705 NP_471042.1 similar to protein gp22 [Bacteriophage A118] NP_471043.1 lin1707 NP_471044.1 lin1708 NP_471045.1 lin1709 NP_471047.1 lin1711 NP_471048.1 lin1712 NP_471049.1 lin1713 NP_471050.1 lin1714 NP_471051.1 lin1715 NP_471052.1 similar to minor capsid protein 1608 - Lactobacillus phage phi-gle NP_471053.1 lin1717 NP_471054.1 lin1718 NP_471055.1 lin1719 NP_471056.1 weakly similar to hypothetical protein of bacteriophage Felix 01 NP_471057.1 lin1721 NP_471058.1 lin1722 NP_471059.1 lin1723 NP_471060.1 lin1724 NP_471061.1 lin1725 NP_471063.1 lin1727 NP_471065.1 lin1729 NP_471066.1 some similarities to plasmid-related proteins NP_471067.1 some similarities to conserved hypothetical proteins NP_471068.1 some similarities to phage related proteins NP_471069.1 weakly similar to phage related proteins NP_471070.1 lin1734 NP_471071.1 lin1735 NP_471072.1 lin1736 NP_471073.1 weakly similar to methyltransferases NP_471074.1 similar to a putative antirepressor [Bacteriophage SPBc2] NP_471075.1 similar to protein gp66 of Bacteriophage A118 NP_471076.1 similar to hypothetical protein of Lactobacillus phage phi-gle NP_471077.1 similar to hypothetical protein from phage P2 NP_471078.1 lin1742 NP_471079.1 similar to phage intagrase proteins NP_471080.1 lin1744 NP_471081.1 lin1745 NP_471082.1 lin1746 NP_471083.1 lin1747 NP_471084.1 lin1748 NP_471085.1 similar to hypothetical protein, Staphylococcus aureus phage phi PVL NP_471086.1 lin1750 NP_471087.1 lin1751 NP_471088.1 similarities Staphylococcus aureus prophage phiPV83 NP_471089.1 lin1753 NP_471090.1 similar to hypothetical protein 44 - Staphylococcus aureus phage phi PVL NP_471091.1 some similarities to phage related proteins NP_471092.1 similar to hypothetical protein of Staphylococcus aureus phage phi PVL NP_471093.1 lin1757 NP_471094.1 lin1758 NP_471095.1 lin1759 NP_471096.1 similar to protein gp43 [Bacteriophage A118] NP_471097.1 similar to transcription regulator NP_471098.1 similar to immunity repressor protein - Bacillus phage phi-105 NP_471099.1 similar to ORF2 [bacteriophage phi-105] NP_471101.1 similar to integrase NP_471102.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_471103.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_471104.1 similar to Antigen C NP_471105.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_471107.1 similar to conserved hypothetical protein NP_471108.1 similar to asparagine synthetase NP_471109.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_471110.1 lin1774 NP_471111.1 similar to L-lactate dehydrogenases NP_471112.1 some similarity to hypothetical proteins NP_471113.1 some similarity to hypothetical proteins NP_471115.1 similar to ABC transporter and adhesion proteins NP_471116.1 similar to O-succinylbenzoic acid-CoA ligase; converts O-succinylbenzoate to O-succinylbenzoyl-CoA NP_471117.1 similar to dihydroxynapthoic acid synthetase; catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA NP_471118.1 similar to prolyl aminopetidases NP_471119.1 similar to 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase / 2-oxoglutarate decarboxylase; SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis NP_471120.1 similar to menaquinone-specific isochorismate synthase; synthesizes isochorismate acid from chorismate NP_471121.1 similar to menaquinone biosynthesis proteins; catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate NP_471122.1 similar to 5-methyltetrahydrofolate-homocysteine methyltransferase (metH); catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions NP_471123.1 similar to cystathionine beta-lyase; catalyzes the formation of L-homocysteine from cystathionine NP_471124.1 similar to cystathionine gamma-synthase NP_471125.1 similar to cobalamin-independent methionine synthase; catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_471126.1 similar to transmembrane transport proteins NP_471127.1 similar to transcription regulators (Fur family), PerR in Bacillus subtilis NP_471128.1 similar to glycerate dehydrogenases NP_471129.1 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate NP_471132.1 similar to glucose 1-dehydrogenase; Catalyzes a key regulatory step in fatty acid biosynthesis NP_471133.1 similar to A/G-specific adenine glycosylase NP_471135.1 similar to deoxyuridine triphosphate nucleotidohydrolases NP_471136.1 lin1800 NP_471137.1 Regulatory protein recX; binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_471138.1 similar to CDP-abequose synthase NP_471139.1 similar to putative membrane proteins NP_471141.1 similar to putative transmembrane proteins NP_471142.1 similar to ribosomal-protein-alanine N-acetyltransferase NP_471143.1 some similarities to methyl-accepting chemotaxis proteins NP_471144.1 lin1808 NP_471145.1 lin1809 NP_471146.1 similar to glutathione transferase - fosfomycin resistance protein NP_471148.1 similar to excinuclease ABC subunit A NP_471149.1 similar to putative AraC-type regulators NP_471150.1 similar to similar to RNA methyltransferases NP_471152.1 similar to deoxyguanosine kinase/deoxyadenosine kinase(I) subunit NP_471153.1 similar to transport proteins NP_471154.1 lin1819 NP_471155.1 similar to aminoglycoside N3'-acetyltransferases NP_471156.1 similar to methionine aminopeptidases; catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn NP_471157.1 similar to putative flavodoxin NP_471158.1 highly similar to aminopeptidases NP_471159.1 similar to multidrug resistance protein, integral membrane protein NP_471160.1 similar to cell-shape determining proteins NP_471162.1 similar to putative transcription regulators NP_471164.1 similar to putative outer surface protein NP_471165.1 similar to phosphotransferase system (PTS) lichenan-specific enzyme IIA component NP_471166.1 similar to phosphotransferase system (PTS) lichenan-specific enzyme IIB component NP_471167.1 similar to transcriptional regulator (NifA/NtrC family) NP_471168.1 similar to ATP-dependent RNA helicases NP_471169.1 lin1834 NP_471170.1 similar to ABC transporter, ATP-binding protein NP_471171.1 similar to transcriptional regulator (GntR family) NP_471173.1 similar to transcription regulators (LacI family) NP_471174.1 some similarities to cellobiose-phosphorylase NP_471175.1 similar to beta-glucosidases NP_471176.1 similar to sugar ABC transporter binding protein NP_471177.1 similar to sugar ABC transporter, permease protein NP_471178.1 similar to sugar ABC transporter, permease protein NP_471179.1 similar to glutamate synthase (small subunit); glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate NP_471180.1 similar to glutamate synthase (large subunit) NP_471183.1 similar to glycerol dehydrogenase NP_471184.1 similar to amino acid ABC transporter (binding protein) NP_471185.1 similar to amino acid (glutamine) ABC transporter (ATP-binding protein) NP_471186.1 similar to amino acid (glutamine) ABC transporter, permease protein NP_471187.1 similar to two-component sensor histidine kinase NP_471188.1 highly similar to adenine deaminases NP_471189.1 lin1854 NP_471191.1 similar to two-component response regulator NP_471192.1 similar to ABC transporter (permease) NP_471193.1 similar to ABC transporter (ATP-binding protein) NP_471194.1 lin1860 NP_471195.1 similar to shikimate kinase NP_471197.1 Uncharacterized RNA methyltransferase lin1863 NP_471198.1 lin1864 NP_471199.1 similar to YegS from E. coli NP_471200.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_471201.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_471202.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_471204.1 similar to DNA ligase; this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_471206.1 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer NP_471207.1 similar to putative sodium-dependent transporter NP_471208.1 lin1874 NP_471210.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_471211.1 involved in de novo purine biosynthesis NP_471212.1 highly similar to phosphoribosylglycinamide formyltransferases NP_471213.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_471214.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_471215.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_471216.1 similar to phosphoribosylformylglycinamidine synthetase II; catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_471217.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway NP_471218.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_471219.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_471220.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway NP_471221.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway NP_471224.1 similar to ABC transporter (ATP-binding protein) NP_471225.1 lin1891 NP_471226.1 similar to aminotripeptidase (peptidase T); catalyzes the release of the N-terminal amino acid from a tripeptide NP_471227.1 lin1893 NP_471228.1 similar to 3'-exo-deoxyribonuclease exoA NP_471229.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_471231.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_471232.1 similar to putative NAD(P)H oxidoreductase NP_471235.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_471236.1 similar to transcription regulator NP_471237.1 weakly similar to Nad(P)h Oxidoreductase chain B NP_471239.1 lin1905 NP_471240.1 similar to Escherichia coli tRNA (guanine-N1) methyltransferase; methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_471241.1 similar to putative 16S rRNA processing protein RimM; Essential for efficient processing of 16S rRNA NP_471245.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_471248.1 similar to protein-tyrosine phosphatase NP_471249.1 similar to signal recognition particle protein Ffh NP_471251.1 similar to FtsY of Escherichia coli and SRP receptor alpha-subunit NP_471252.1 similar to Smc protein essential for chromosome condensation and partition NP_471253.1 similar to ribonuclease III; cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_471254.1 highly similar to acyl carrier proteins; carries the fatty acid chain in fatty acid biosynthesis NP_471255.1 similar to 3-ketoacyl-acyl carrier protein reductase NP_471256.1 similar to malonyl CoA-acyl carrier protein transacylase NP_471257.1 similar to plsX protein involved in fatty acid/phospholipid synthesis; involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY NP_471258.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria NP_471259.1 similar to ATP-dependent DNA helicase recG; catalyzes branch migration in Holliday junction intermediates NP_471260.1 similar to L-serine dehydratase NP_471261.1 similar to phosphoglycerate dehydrogenase NP_471264.1 required for 70S ribosome assembly NP_471265.1 weakly similar to thiamin pyrophosphokinase NP_471266.1 similar to ribulose-5-phosphate 3-epimerase; catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_471267.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity NP_471268.1 similar to putative serine/threonine-specific protein kinase NP_471269.1 similar to putative phosphoprotein phosphatase NP_471270.1 similar to RNA-binding Sun protein NP_471271.1 similar to methionyl-tRNA formyltransferase NP_471272.1 similar to primosomal replication factor Y; binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_471273.1 similar to pantothenate metabolism flavoprotein homolog NP_471274.1 lin1940; Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_471275.1 similar to guanylate kinases; Essential for recycling GMP and indirectly, cGMP NP_471276.1 similar to conserved hypothetical protein NP_471277.1 similar to fibronectin binding proteins NP_471278.1 similar to conserved hypotheticl proteins NP_471279.1 highly similar to orotate phosphoribosyltransferases; involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_471280.1 highly similar to orotidine 5'-phosphate decarboxylases; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_471281.1 highly similar to dihydroorotase dehydrogenase; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits NP_471282.1 highly similar to dihydroorotate dehydrogenase (electron transfer subunit) NP_471283.1 highly similar to carbamoyl-phosphate synthetase (catalytic subunit); four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_471284.1 highly similar to carbamoyl-phosphate synthetase (glutaminase subunit); catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_471285.1 highly similar to dihydroorotase; catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_471286.1 highly similar to aspartate carbamoyltransferase; catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_471287.1 highly similar to uracil permease NP_471288.1 highly similar to pyrimidine operon regulatory protein; regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity NP_471289.1 lin1955 NP_471292.1 highly similar to signal peptidase II; lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_471294.1 Probable multidrug resistance protein norM (Multidrug-efflux transporter); NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones NP_471295.1 similar to adhesion binding proteins and lipoproteins with multiple specificity for metal cations (ABC transporter) NP_471296.1 similar metal cations ABC transporter (permease protein) NP_471297.1 similar to metal cations ABC transporter, ATP-binding proteins NP_471298.1 similar to transcriptional regulator (MarR family) NP_471299.1 similar to carboxy-terminal processing proteinase NP_471300.1 similar to putative mercuric ion binding proteins NP_471301.1 similar to heavy metal-transporting ATPases NP_471303.1 similar to similar to D-alanyl-D-alanine carboxypeptidases NP_471304.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate NP_471305.1 similar to hypoyhetical protein NP_471306.1 similar to dehydogenases and hypothetical proteins NP_471307.1 similar to transcriptional regulator (PilB family); this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress NP_471308.1 similar to peptidyl methionine sulfoxide reductases; this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_471312.1 similar to hemolysinIII proteins, putative integral membrane protein NP_471315.1 similar to pyruvate phosphate dikinase; catalyzes the formation of phosphoenolpyruvate from pyruvate NP_471317.1 similar to conserved hypothetical proteins, putative integral membrane protein NP_471318.1 similar to alkaline phosphatase NP_471319.1 similar to phosphoglucomutases NP_471320.1 similar to methyltransferases NP_471321.1 similar to dihydrofolate reductases NP_471322.1 similar to thymidylate synthase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived NP_471323.1 similar to putative ABC transporters (ATP-binding protein) NP_471324.1 similar to formyl-tetrahydrofolate synthetase; catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate NP_471325.1 similar o transcriptional regulators; involved in manganese homeostasis; activates the transcription of the mntABCD operon NP_471326.1 similar to cold shock protein NP_471327.1 similar to similar to RNase HI NP_471328.1 similar to 5'-3' exonuclease NP_471329.1 similar to ribosomal protein S14; located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_471330.1 similar to chitinases NP_471331.1 similar to xanthine permeases NP_471332.1 similar to xanthine phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine NP_471333.1 similar to probable thermostable carboxypeptidases NP_471339.1 similar to DNA repair and homologous recombination protein; functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC NP_471340.1 similar to penicillin-binding protein 2A NP_471341.1 lin2007 NP_471343.1 similar to chromosome replication initiation protein NP_471344.1 similar to asparaginyl-tRNA synthetases; catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_471345.1 similar to aspartate aminotransferases; catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_471347.1 similar to ATP-dependent helicases; unwinds DNA NP_471348.1 similar to aspartate 1-decarboxylases; Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) NP_471349.1 similar to panthotenate synthetases; catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_471350.1 similar to ketopantoate hydroxymethyltransferases; catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_471351.1 similar to thioredoxin NP_471352.1 similar to transcriptional regulator and biotin acetyl-CoA-carboxylase synthetase NP_471353.1 similar to tRNA CCA-adding enzyme; catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity NP_471354.1 similar to methylglyoxal synthase; catalyzes the formation of methylglyoxal from glycerone phosphate NP_471355.1 similar to dihydrodipicolinate reductase; catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_471358.1 similar to oxidoreductases NP_471359.1 similar to unknown proteins (hypothetical sensory transduction histidine kinase) NP_471360.1 similar to unknown proteins (hypothetical sensory transduction histidine kinase) NP_471363.1 similar to malolactic enzyme (malate dehydrogenase); malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate NP_471364.1 similar to peptidase NP_471365.1 similar to pyruvate formate-lyase NP_471371.1 similar to 5-enolpyruvylshikimate-3-phosphate synthase; catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_471372.1 similar to prephenate dehydrogenase; catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate NP_471373.1 similar to histidinol-phosphate aminotransferase and tyrosine/phenylalanine aminotransferase; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis NP_471374.1 similar to chorismate mutase NP_471375.1 similar to 3-dehydroquinate synthase; catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_471376.1 similar to chorismate synthase; catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_471377.1 similar to nucleoside diphosphate kinase; catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_471378.1 similar to heptaprenyl diphosphate synthase component II (menaquinone biosynthesis) NP_471379.1 similar to 2-heptaprenyl-1,4-naphthoquinone methyltransferase; Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_471380.1 similar to heptaprenyl diphosphate synthase component I NP_471381.1 similar to GTP cyclohydrolase I; involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_471382.1 similar to non-specific DNA-binding protein HU NP_471383.1 similar to protein-tyrosine/serine phosphatase NP_471384.1 similar to NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_471385.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_471386.1 similar to similar to ribosomal protein S1 like protein; in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_471387.1 similar to cytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_471388.1 similar to asparaginase NP_471390.1 similar to ATP-dependent DNA helicase NP_471392.1 similar to ferredoxin NP_471394.1 similar to similar to acyl-CoA hydrolase NP_471395.1 similar to two-component sensor histidine kinase (ResE) NP_471396.1 similar to two-component response regulator (ResD) NP_471399.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB NP_471400.1 similar to diaminopimelate decarboxylase NP_471401.1 similar to purine-nucleoside phosphorylase; catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation NP_471402.1 similar to phosphopentomutase; catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose NP_471403.1 similar to integrase/recombinase NP_471404.1 similar to transcriptional regulator (Fur family) NP_471405.1 similar to ferrichrome ABC transporter (permease) NP_471406.1 similar to ferrichrome ABC transporter (permease) NP_471407.1 similar to ferrichrome binding protein NP_471408.1 similar to ferrichrome ABC transporter (ATP-binding protein) NP_471409.1 similar to oxidoreductases NP_471410.1 similar to transcription regulators (TetR family) NP_471412.1 similar to ABC transporter, ATP-binding protein NP_471415.1 similar to toxic ion resistance proteins NP_471416.1 similar to Escherichia coli DNA-damage-inducible protein dinP; involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function NP_471417.1 similar to oxidoreductase NP_471419.1 similar to glucose-6-phosphate 1-dehydrogenase; catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_471421.1 lin2087 NP_471424.1 similar to dihydroxy-acid dehydratase; catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_471425.1 similar to acetolactate synthase (acetohydroxy-acid synthase) (large subunit) NP_471426.1 similar to acetolactate synthase (acetohydroxy-acid synthase) (small subunit); with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_471427.1 similar to ketol-acid reductoisomerase (acetohydroxy-acid isomeroreductase); catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_471428.1 similar to 2-isopropylmalate synthase; catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis NP_471429.1 similar to 3-isopropylmalate dehydrogenase; catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis NP_471430.1 similar to 3-isopropylmalate dehydratase (large subunit); dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate NP_471431.1 similar to 3-isopropylmalate dehydratase (small subunit); catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D NP_471432.1 similar to threonine dehydratase; catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic NP_471433.1 similar to alpha-acetolactate decarboxylase NP_471434.1 similar to p60-related proteins NP_471435.1 similar to pyrimidine-nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway NP_471436.1 similar to transcription regulators (LacI family) NP_471437.1 similar to deoxyribose-phosphate aldolase; catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate NP_471438.1 similar to transcription repressor of dra/nupC/pdp operon DeoR NP_471439.1 similar to PTS mannose-specific enzyme IIA component NP_471440.1 similar to opine catabolism protein NP_471441.1 weakly similar to glucosamine-fructose-6-phosphate aminotransferase NP_471442.1 similar to PTS mannose-specific enzyme IID component NP_471443.1 similar to PTS mannose-specific enzyme IIC component NP_471444.1 similar to PTS mannose-specific enzyme IIB component NP_471445.1 similar to transcription regulator GntR family NP_471446.1 similar to transcription regulator GntR family NP_471447.1 similar to oxidoreductase NP_471448.1 similar to alpha-acetolactate synthase protein, AlsS; catalyzes the formation of 2-acetolactate from pyruvate in stationary phase NP_471449.1 weakly similar to putative sugar-binding lipoproteins NP_471450.1 similar to putative ABC transporter, permease protein NP_471451.1 similar to putative transport system integral membrane protein NP_471452.1 similar to two-component response regulator NP_471453.1 similar to two-component sensor histidine kinase NP_471456.1 similar to putative sugar hydrolases NP_471457.1 similar to alpha-mannosidase NP_471458.1 similar to major cold-shock protein NP_471460.1 similar to diaminopimelate epimerase; involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_471461.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme NP_471462.1 similar to cell-division initiation protein (septum placement) NP_471464.1 similar to a NifS-like protein required for NAD biosynthesis NP_471465.1 similar to L-aspartate oxidase; catalyzes the formation of oxaloacetate from L-aspartate NP_471466.1 similar to nicotinate-nucleotide pyrophosphorylase; catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide NP_471467.1 similar to quinolinate synthetase; 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_471472.1 highly similar to cell-division initiation protein FtsZ; GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_471473.1 highly similar to cell-division protein FtsA NP_471474.1 similar to cell-division initiation protein divIB NP_471475.1 similar to peptidoglycan synthesis enzymes, putative phospho-N-acetylmuramoyl-pentapeptide-transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_471476.1 similar to UDP-N-acetylmuramoylalanine D-glutamate ligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_471477.1 similar to phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_471478.1 similar to UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase; involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_471479.1 similar to penicillin-binding protein 2B NP_471480.1 similar to cell-division protein FtsL NP_471482.1 MraZ; UPF0040; crystal structure shows similarity to AbrB NP_471483.1 similar to integral membrane proteins NP_471484.1 similar to transporter binding proteins NP_471485.1 lin2151 NP_471486.1 weakly similar to ketopantoate reductase involved in thiamin biosynthesis; ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis NP_471487.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_471490.1 similar to excinuclease ABC (subunit A) NP_471491.1 weakly similar to proteases NP_471492.1 similar to phosphopantetheine adenylyltransferase; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_471497.1 highly similar to heme A farnesyltransferase; converts protoheme IX and farnesyl diphosphate to heme O NP_471498.1 similar to heme O oxygenase NP_471499.1 similar to potassium channel subunit NP_471502.1 similar to copper export proteins NP_471503.1 lin2169 NP_471504.1 similar to large conductance mechanosensitive channel protein; homopentamer; channel that opens in response to pressure or hypoosmotic shock NP_471505.1 lin2171 NP_471506.1 lin2173 NP_471507.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_471508.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_471510.1 lin2177 NP_471511.1 similar to a putative DNA binding proteins; modulates transcription in response to the NADH/NAD(+) redox state NP_471512.1 similar to ABC transporter (ATP-binding protein) NP_471514.2 similar to glycoprotein endopeptidase; in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_471515.1 similar to ribosomal protein alanine acetyltransferase NP_471516.1 similar to glycoprotease NP_471518.1 lin2185 NP_471519.1 lin2186 NP_471520.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_471521.1 similar to unknown proetin; may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_471522.1 lin2189 NP_471523.1 lin2190 NP_471524.1 weakly similar to transcription regulators NP_471526.1 similar to transcription regulators NP_471527.1 similar to lipases NP_471528.1 similar to argininosuccinate synthase; catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_471529.1 similar to argininosuccinate lyase; catalyzes the formation of arginine from (N-L-arginino)succinate NP_471531.1 similar to L-fuculose-phosphate aldolase NP_471532.1 similar to 1-phosphofructokinase NP_471533.1 similar to PTS system galactitol-specific enzyme IIC component NP_471534.1 similar to PTS system galactitol-specific enzyme IIB component NP_471535.1 similar to PTS system galactitol-specific enzyme IIA component NP_471536.1 similar to transcription antiterminator NP_471537.1 similar to transcriptional regulator (GntR family) and to aminotransferase (MocR-like) NP_471538.1 similar to a protein required for pyridoxine synthesis; with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate NP_471539.1 lin2206; with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate NP_471540.1 similar to phosphotransacetylase; in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta NP_471541.1 lin2208 NP_471542.1 similar to ferrous iron transport protein B NP_471543.1 lin2210 NP_471545.1 similar to transcriptional regulator (DeoR family) NP_471546.1 similar to N-acetylglucosamine-6-phosphate deacetylase NP_471547.1 similar to hydrolase NP_471548.1 similar to mannnose-6 phospate isomerase NP_471549.1 similar to FMN-containing NADPH-linked nitro/flavin reductase NP_471550.1 lin2217 NP_471552.1 similar to ABC transporter (ATP-binding protein) NP_471553.1 similar to ABC transporter (permease) NP_471554.1 lin2221 NP_471556.1 similar to phosphoglucomutase; catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_471559.1 similar to maltosephosphorylase NP_471560.1 similar to maltodextrose utilization protein MalA NP_471561.1 similar to maltodextrin ABC-transport system (permease) NP_471562.1 similar to maltodextrin ABC-transport system (permease) NP_471563.1 similar to maltose/maltodextrin ABC-transporter (binding protein) NP_471564.1 similar to maltogenic amylase NP_471565.1 lin2232 NP_471566.1 similar to transcription regulator, LacI family NP_471567.1 lin2234 NP_471569.1 lin2236 NP_471570.1 lin2237 NP_471571.1 similar to fructose-1,6-biphosphate aldolase type II NP_471572.1 similar to fructose-1,6-biphosphate aldolase type II NP_471573.1 similar to PTS system, fructose-specific enzyme IIC component NP_471574.1 similar to PTS system, fructose-specific enzyme IIB component NP_471575.1 similar to PTS system, fructose-specific enzyme IIA component NP_471576.1 similar to transcription regulator NP_471577.1 similar to ABC transporter (ATP-binding protein) NP_471578.1 similar to ABC transporter (membrane protein) NP_471580.1 lin2248 NP_471582.1 similar to transcription regulator LysR family NP_471586.1 lin2254 NP_471588.1 similar to thioredoxin NP_471589.1 similar to flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_471590.1 similar to ribonucleoside-diphosphate reductase, subunit beta; B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_471591.1 similar to ribonucleoside-diphosphate reductase, subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis NP_471592.1 lin2260 NP_471593.1 similar to Bacillus subtilis YwmG protein NP_471594.1 similar to oxidoreductase NP_471596.1 lin2264 NP_471598.1 similar to oxidoreductase NP_471599.1 similar to transcriptional regulator (AraC/XylS family) NP_471600.1 similar to transcription regulator CRP/FNR family NP_471601.1 lin2269 NP_471603.1 similar to glyoxalase I NP_471604.1 lin2272 NP_471606.1 similar to antiporter proteins NP_471607.1 similar to propionate CoA-transferase NP_471608.1 similar to sigma-54-dependent transcriptional activator NP_471610.1 similar to dehydrogenase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_471611.1 similar to transcriptional regulator (tetR family) NP_471618.1 similar to ferrichrome ABC transporter (ATP-binding protein) NP_471619.1 similar to ferrichrome ABC transporter (permease) NP_471620.1 similar to ferrichrome ABC transporter (binding protein) NP_471621.1 lin2289 NP_471622.1 lin2290 NP_471623.1 lin2291 NP_471624.1 similar to oligoendopeptidase NP_471625.1 similar to a putative competence protein from streptococcus pneumoniae NP_471626.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence NP_471627.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress NP_471628.1 similar to oligopeptide ABC transporter (ATP-binding protein) NP_471629.1 similar to oligopeptide ABC transporter (ATP-binding protein) NP_471630.1 similar to oligopeptide ABC transporter (permease) NP_471631.1 similar to oligopeptide ABC transporter (permease) NP_471632.1 similar to pheromone ABC transporter (binding protein) NP_471633.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_471635.1 similar to transcription regulator NP_471636.1 similar to 3-oxoacyl-acyl-carrier protein synthase NP_471637.1 similar to 3-oxoacyl- acyl-carrier protein synthase; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_471638.1 similar to N-acetylmuramoyl-L-alanine amidase and to internalin B NP_471640.1 similar to phosphoglyceromutase 1 NP_471641.1 similar to endopeptidase Clp ATP-binding chain B (ClpB) NP_471644.1 lin2312 NP_471645.1 lin2313 NP_471646.1 similar to ferrochelatase; protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_471647.1 similar to uroporphyrinogen III decarboxylase; catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_471649.1 similar to ABC transporter (membrane protein) NP_471650.1 similar to ABC transporter (ATP-binding protein) NP_471651.1 similar to histidine triad (HIT) protein NP_471653.1 lin2321 NP_471654.1 similar to post-translocation molecular chaperone NP_471655.1 similar to S. aureus Cbf1 protein; catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates NP_471660.1 similar to fumarate hydratase; class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle NP_471661.1 similar to ABC transporter (ATP-binding protein) NP_471662.1 similar to penicillin-binding protein NP_471663.1 similar to arsenate reductase NP_471666.1 similar to transcriptional regulators (LysR family) NP_471668.1 similar to NADH oxidase NP_471669.1 similar to oxidoreductase; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_471670.1 similar to transport system permease protein NP_471671.1 similar to transport system permease protein NP_471672.1 lin2341 NP_471673.1 similar to ABC transporter (ATP-binding protein) NP_471674.1 similar to transcriptional regulators (GntR family) NP_471675.1 similar to O6-methylguanine-DNA methyltransferase NP_471676.1 similar to methylphosphotriester-DNA alkyltransferase and transcriptional regulator NP_471677.1 similar to putative ribosomal large subunit pseudouridine synthase NP_471680.1 similar to oxidoreductase NP_471682.1 similar to low-affinity inorganic phosphate transporter NP_471683.1 similar to amino acid ABC transporter, permease protein NP_471684.1 similar to amino acid ABC transporter (ATP-binding protein) NP_471685.1 similar to aspartate aminotransferase; catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_471686.1 similar to phosphoglucomutase NP_471688.1 lin2357 NP_471690.1 lin2359 NP_471691.1 similar to phosphotransferase system (PTS) beta-glucoside-specific enzyme IIA NP_471695.1 similar to unkown proteins NP_471699.1 similar to ATP-dependent deoxyribonuclease (subunit A) NP_471700.1 similar to ATP-dependent deoxyribonuclease (subunit B) NP_471701.1 lin2370 NP_471702.1 similar to competence transcription factor ComK, N terminal part NP_471703.1 lin2372 NP_471704.1 similar to AbiD phage protein NP_471705.1 similar to N-acetylmuramoyl-L-alanine amidase (N-terminal part) and to L-alanoyl-D-glutamate peptidase (C-terminal part) NP_471706.1 similar to phage related proteins NP_471707.1 lin2376 NP_471708.1 lin2377 NP_471709.1 lin2378 NP_471710.1 similar to protein gp20 [Bacteriophage A118] NP_471711.1 similar to protein gp19 [Bacteriophage A118] NP_471712.1 similar to protein R372 - Lactobacillus phage phi-gle NP_471713.1 similar to gp17 [Bacteriophage A118] NP_471714.1 similar to hypothetical protein [Lactobacillus casei bacteriophage A2] NP_471715.1 lin2384 NP_471716.1 similar to protein gp13 [Bacteriophage A118] NP_471717.1 lin2386 NP_471718.1 lin2387 NP_471719.1 lin2388 NP_471720.1 lin2389 NP_471721.1 similar to main capsid protein Gp34 - Lactobacillus delbrueckii subsp. bulgaricus phage mv4 NP_471722.1 lin2391 NP_471723.1 similar to protein gp4 [Bacteriophage A118] NP_471724.1 lin2393 NP_471725.1 lin2394 NP_471726.1 some similarities to phage-related terminase small subunit homolog yqaS NP_471727.1 lin2396 NP_471728.1 similar to sigma factor-like positive control protein of Bacillus subtilis; Positive regulatory protein that acts at the late promoter PL NP_471730.1 lin2399 NP_471731.1 similar to Lactococcus lactis prophage pi3 protein 45 NP_471732.1 lin2401 NP_471733.1 similar to single-stranded DNA-binding protein NP_471734.1 lin2403 NP_471735.1 lin2404 NP_471736.1 lin2405 NP_471737.1 Protein gp52 [Bacteriophage A118] NP_471738.1 lin2408 NP_471739.1 similar to intrgase proteins NP_471740.1 similar to phage related proteins NP_471741.1 lin2411 NP_471742.1 highly similar to gp49 [Bacteriophage A118] NP_471743.1 highly similar to putative recombinase [Bacteriophage A118] NP_471744.1 gp47 [Bacteriophage A118] NP_471745.1 lin2415 NP_471746.1 gp44 [Bacteriophage A118] NP_471747.1 gp43 [Bacteriophage A118] NP_471748.1 similar to anti-repressor NP_471749.1 lin2419 NP_471750.1 similar to Bacteriophage A118 protein gp40 NP_471751.1 lin2421 NP_471752.1 similar to Bacteriophage A118 putative repressor protein NP_471753.1 similar to Bacteriophage A118 protein gp34 NP_471754.1 similar to protein gp33 [Bacteriophage A118] NP_471755.1 lin2425 NP_471756.1 putative integrase [Bacteriophage A118] NP_471758.1 similar to transcriptional regulator NP_471759.1 highly similar to phosphotransferase system (PTS) fructose-specific enzyme IIABC component NP_471761.1 similar to regulatory protein DeoR family NP_471764.1 similar to Erwinia chrysanthemi IndA protein NP_471765.1 similar to carbohydrate kinases NP_471766.1 similar to 16S pseudouridylate synthase NP_471767.1 similar to nitrilotriacetate monooxygenase NP_471768.1 similar to Bacillus subtilis YtnI protein NP_471770.1 similar to amino acid ABC-transporter, ATP-binding protein NP_471771.1 similar to amino acid ABC transporter (permease) NP_471772.1 similar to amino acid ABC-transporter (permease) NP_471773.1 similar to amino acid ABC transporter (binding protein) NP_471774.1 similar to Bacillus subtilis YtmI protein NP_471775.1 similar to NADH-dependent FMN reductase NP_471776.1 similar to LysR family transcription regulator NP_471777.1 similar to putative Na+/H+ antiporter NP_471779.1 Similar to multidrug resistance protein NP_471780.1 lin2450 NP_471782.1 similar to N-acetylglucosamine-6-phosphate isomerase NP_471784.1 similar to 6-phospho-beta-glucosidase NP_471785.1 similar to transcription antiterminator BglG family NP_471787.1 similar to PTS system, cellobiose-specific enzyme IIA component NP_471788.1 similar to PTS system, cellobiose-specific enzyme IIB component NP_471789.1 similar to PTS system, cellobiose-specific enzyme IIC component NP_471792.1 similar to amino acid antiporter (acid resistance) NP_471793.1 similar to glutamate decarboxylase NP_471794.1 similar to S. pyogenes RofA regulatory protein NP_471795.1 similar to transcription regulator DeoR family NP_471796.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_471797.1 lin2467 NP_471798.1 similar to Bacillus subtilis general stress protein 13 containing a ribosomal S1 protein domain; induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation NP_471799.1 similar to aminotransferase NP_471800.1 similar to putative ABC-transporter transmembrane subunit NP_471801.1 similar to ABC-transporter ATP binding proteins NP_471802.1 similar to phosphotransferase system (PTS) beta-glucoside-specific enzyme IIB component NP_471803.1 similar to aspartate kinase; catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive NP_471804.1 lin2474 NP_471805.1 similar to peptidyl-prolyl cis-trans isomerase NP_471806.1 similar to multi-drug resistance efflux pump NP_471807.1 similar to proteins involved in resistance to cholate and to NA(+) and in pH homeostasis; subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_471808.1 similar to proteins involved in resistance to cholate and to NA(+) and in pH homeostasis; subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport NP_471809.1 similar to proteins involved in resistance to cholate and to NA(+) and in pH homeostasis; subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_471810.1 similar to proteins involved in resistance to cholate and to NA(+) and in pH homeostasis; subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone NP_471811.1 similar to proteins involved in resistance to cholate and to NA(+) and in pH homeostasis; subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_471812.1 similar to proteins involved in resistance to cholate and to NA(+) and in pH homeostasis; subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_471813.1 similar to proteins involved in resistance to cholate and to NA(+) and in pH homeostasis; subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_471814.1 similar to Bacillus subtilis YuxO protein NP_471815.1 similar to Bacillus subtilis YuiD protein NP_471816.1 similar to Bacillus subtilis YwqG protein NP_471818.1 similar to NADH dehydrogenase NP_471819.1 similar to hypothetical thioredoxine reductase NP_471820.1 conserved hypothetical protein similar to Bacillus subtilis YhfK protein NP_471821.1 similar to Bacillus subtilis YuzB protein NP_471822.1 similar to Bacillus subtilis YuzD protein NP_471825.1 similar to internalin proteins, putative peptidoglycan bound protein (LPXTG motif) NP_471826.1 similar to NifU protein NP_471829.1 similar to acetyltransferase NP_471830.1 similar to conserved hypothetical protein and to Bacillus subtilis YutF protein NP_471831.1 similar to Bacillus subtilis YutD protein NP_471832.1 similar to Bacillus subtilis YunD protein NP_471834.1 lin2504 NP_471835.1 similar to Bacillus subtilis YunF protein NP_471838.1 similar to aminotransferase NP_471839.1 similar to aminotransferase NP_471840.1 similar to ABC transporter, ATP-binding protein NP_471841.1 lin2511 NP_471842.1 conserved lipoprotein (putative ABC transporter binding protein) NP_471843.1 similar to ABC transporter, permease protein NP_471844.1 similar to ABC transporter (ATP-binding protein) NP_471845.1 similar to two-component sensor histidine kinase NP_471846.1 similar to two-component response regulator NP_471848.1 similar to thioredoxin NP_471849.1 similar to glycine cleavage system protein H; part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor NP_471851.1 similar to cell division proteins RodA, FtsW NP_471852.1 similar to cell division proteins RodA, FtsW NP_471853.1 similar to Bacillus subtilis ferrichrome ABC transporter (ATP-binding protein) FhuC NP_471854.1 similar to Bacillus subtilis ferrichrome ABC transporter (permease) FhuG NP_471855.1 similar to Bacillus subtilis ferrichrome ABC transporter fhuD precursor (ferrichrome-binding protein) NP_471856.1 lin2526 NP_471857.1 similar to acetylesterase NP_471858.1 highly similar to glutamate decarboxylases NP_471859.1 similar to Bacillus subtilis YfhL protein NP_471860.1 similar to transcription antiterminator NP_471861.1 lin2531 NP_471862.1 lin2532 NP_471863.1 lin2533 NP_471864.1 lin2534 NP_471865.1 similar to transcription regulator NP_471866.1 lin2536 NP_471867.1 similar to internalin proteins NP_471868.1 similar to glycosidase NP_471869.1 similar to internalin NP_471870.1 similar to glycosidase NP_471871.1 similar to transcription regulator NP_471872.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_471873.1 similar to exoribonuclease RNase-R NP_471874.1 similar to carboxylesterase NP_471875.1 similar to preprotein translocase subunit SecG NP_471876.1 similar to carboxylesterase NP_471877.1 similar to lipolytic enzyme NP_471878.1 lin2548 NP_471879.1 highly similar to enolase; enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_471880.1 highly similar to phosphoglycerate mutase; catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate NP_471881.1 highly similar to triose phosphate isomerase; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_471882.1 highly similar to phosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_471883.1 highly similar to glyceraldehyde 3-phosphate dehydrogenase; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate NP_471884.1 similar to Bacillus subtilis CggR hypothetical transcriptional regulator NP_471885.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen NP_471886.1 similar to dipeptidases NP_471887.1 similar to transport protein NP_471888.1 similar to transcription regulator NP_471889.1 lin2559 NP_471890.1 lin2560 NP_471893.1 similar to N-acetylmuramoyl-L-alanine amidase (N-terminal part) and to L-alanoyl-D-glutamate peptidase (C-terminal part) NP_471894.1 lin2564 NP_471895.1 similar to protein gp20 [Bacteriophage A118] NP_471896.1 similar to endopeptidase [bacteriophage bIL285] NP_471897.1 similar to Orf53 [bacteriophage bIL285] NP_471898.1 similar to tail protein [bacteriophage bIL285] NP_471899.1 similar to Lactococcus lactis prophage pi2 protein 41 NP_471900.1 similar to Orf51 [bacteriophage bIL285] NP_471901.1 similar to Orf50 [bacteriophage bIL285] NP_471902.1 similar to Orf49 [bacteriophage bIL285] NP_471903.1 similar to Orf48 [bacteriophage bIL285] NP_471904.1 similar to Orf47 [bacteriophage bIL285] NP_471905.1 similar to Orf46 [bacteriophage bIL285] NP_471906.1 similar to capsid protein [bacteriophage bIL285] NP_471907.1 similar to protease [bacteriophage bIL285] NP_471908.1 similar to portal protein [bacteriophage bIL285] NP_471909.1 similar to terminase [bacteriophage bIL285] NP_471910.1 similar to bacteriophage protein NP_471911.1 similar to bacteriophage protein NP_471912.1 lin2582 NP_471913.1 lin2583 NP_471914.1 lin2584 NP_471915.1 lin2585 NP_471916.1 similar to bacteriophage protein NP_471917.1 similar to bacteriophage protein NP_471918.1 similar to bacteriophage protein NP_471919.1 similar to DEAH-family helicase NP_471920.1 similar to bacteriophage protein NP_471921.1 similar to bacteriophage protein NP_471922.1 lin2592 NP_471924.1 lin2594 NP_471925.1 lin2595 NP_471926.1 lin2596 NP_471927.1 lin2597 NP_471928.1 lin2598 NP_471929.1 lin2599 NP_471930.1 lin2600 NP_471931.1 similar to bacteriophage integrase NP_471932.1 similar to phage protein NP_471933.1 lin2603 NP_471934.1 lin2604 NP_471935.1 lin2605 NP_471936.1 lin2606 NP_471937.1 similar to a putative repressor protein [Bacteriophage A118] NP_471938.1 similar to protein gp35 from Bacteriophage A118 NP_471939.1 lin2609 NP_471940.1 similar to integrases NP_471941.1 similar to chitinase and chitin binding protein NP_471942.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_471943.1 similar to amino acid transporter NP_471944.1 similar to NADH oxidase; catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds NP_471948.1 similar to phosphomannomutase and phosphoglucomutase NP_471949.1 similar to aldose 1-epimerase (mutarotase) NP_471952.1 lin2622 NP_471953.1 similar to acetyltransferase NP_471954.1 similar to Bacillus subtilis P-Ser-HPr phosphatase; hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation NP_471955.1 highly similar to prolipoprotein diacylglyceryl transferase; transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_471956.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system NP_471957.1 similar to Bacillus subtilis YvlD protein NP_471958.1 similar to Bacillus subtilis yvlC protein NP_471959.1 lin2629 NP_471960.1 similar to Bacillus subtilis YvlB protein NP_471961.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_471962.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_471963.1 similar to Bacillus subtilis CsbA protein NP_471964.1 lin2634 NP_471965.1 lin2635 NP_471966.1 similar to transcription regulator ArsR family NP_471967.1 similar to negative regulator of phosphate regulon NP_471968.1 similar to phosphate ABC transporter (ATP-binding protein); ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_471969.1 similar to phosphate ABC transporter (ATP-binding protein); ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_471970.1 similar to phosphate ABC transporter (permease protein) NP_471971.1 similar to phosphate ABC transporter (permease protein) NP_471972.1 similar to phosphate ABC transporter (binding protein) NP_471975.1 lin2645 NP_471976.1 similar to cardiolipin synthase NP_471977.1 similar to cell wall binding proteins NP_471979.1 highly similar to cell-division protein FtsX NP_471980.1 highly similar to the cell-division ATP-binding protein FtsE NP_471982.1 highly similar to peptide chain release factor 2; recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_471983.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_471984.1 similar to conserved hypothetical proteins like to Bacillus subtilis YvyD protein NP_471985.1 similar to late competence protein comFC NP_471986.1 similar to late competence protein comFA NP_471987.1 similar to Bacillus subtilis YviA (DegV) protein NP_471988.1 similar to Bacillus subtilis two-component response regulator DegU NP_471990.1 lin2661 NP_471991.1 similar to Bacillus subtilis putative transcriptional regulator LytR NP_471992.1 similar to Bacillus subtilis TagO teichoic acid linkage unit synthesis protein NP_471993.1 similar to Bacillus subtilis O-succinylbenzoate-CoA synthase (MenC) NP_471994.1 similar to Bacillus subtilis TagA protein involved in polyglycerol phosphate biosynthesis NP_471995.1 similar to hypothetical cell wall binding protein from Bacillus subtilis NP_471996.1 similar to single-strand DNA-binding protein NP_471997.1 similar to hydroxymyristoyl-(acyl carrier protein) dehydratase; in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP NP_471998.1 similar to MreB-like protein NP_471999.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_472000.1 similar to Bacillus subtilis YwzB protein NP_472001.1 highly similar to H+-transporting ATP synthase chain epsilon; part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_472002.1 highly similar to H+-transporting ATP synthase chain beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_472003.1 highly similar to H+-transporting ATP synthase chain gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_472004.1 highly similar to H+-transporting ATP synthase chain alpha; produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_472005.1 highly similar to H+-transporting ATP synthase chain delta; Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_472006.1 highly similar to H+-transporting ATP synthase chain b; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel NP_472007.1 highly similar to H+-transporting ATP synthase chain c; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 NP_472008.1 highly similar to H+-transporting ATP synthase chain a; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_472009.1 highly similar to ATP synthase subunit i NP_472010.1 similar to UDP-N-acetylglucosamine 2-epimerase NP_472011.1 highly similar to uracil phosphoribosyltransferase; Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate NP_472012.1 highly similar to glycine hydroxymethyltransferase; catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_472013.1 similar to phosphatases NP_472014.1 similar to yeast translation initiation protein NP_472015.1 similar to protoporphyrinogen oxidase NP_472016.1 highly similar to peptide chain release factor 1; recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_472017.1 similar to thymidine kinase; catalyzes the formation of thymidine 5'-phosphate from thymidine NP_472018.1 highly similar to homoserine kinase; catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_472019.1 highly similar to threonine synthase; catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_472020.1 highly similar to homoserine dehydrogenase; catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_472021.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_472022.1 lin2693 NP_472024.1 similar to glycosyl transferases NP_472025.1 highly similar to transcription terminator factor rho; An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_472026.1 highly similar to UDP-N-acetylglucosamine 1-carboxyvinyltransferase; adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_472028.1 similar to galactosyltransferase NP_472029.1 weakly similar to human N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein NP_472030.1 highly similar to fructose-1,6-bisphosphate aldolase type II NP_472031.1 similar to YegS from E. coli NP_472033.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_472034.1 similar to Bacillus subtilis RNA polymerase delta subunit; participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling NP_472035.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_472036.1 lin2707 NP_472038.1 similar to 4-oxalocrotonate isomerase NP_472040.1 lin2711 NP_472041.1 lin2712 NP_472042.1 lin2713 NP_472043.1 similar to dipeptide ABC transporter (dipeptide-binding protein) NP_472044.1 lin2715 NP_472045.1 similar to nicotinamidase NP_472046.1 similar to Chain A, Dihydrofolate Reductase NP_472047.1 similar to zinc-binding dehydrogenase NP_472048.1 lin2719 NP_472049.1 similar to cation transport protein (efflux) NP_472051.1 lin2722 NP_472054.1 similar to ABC transporter, ATP-binding protein NP_472056.1 similar to two-component sensor histidine kinase NP_472057.1 similar to two-component response regulator NP_472058.1 similar to formate dehydrogenase associated protein; involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth NP_472059.1 similar to Bacillus subtilis YrhD protein NP_472060.1 similar to formate dehydrogenase alpha chain NP_472062.1 similar to drug-export proteins NP_472063.1 similar to transcription regulator TetR/AcrR family NP_472064.1 lin2735 NP_472065.1 lin2736 NP_472066.1 similar to ATP binding proteins NP_472068.1 similar to oxidoreductase, aldo/keto reductase family NP_472069.1 similar to transcription regulators (MerR family) NP_472070.1 lin2741 NP_472071.1 lin2742 NP_472072.1 lin2743 NP_472074.1 forms a direct contact with the tRNA during translation NP_472075.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_472076.1 highly similar to pseudouridylate synthase I; mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_472077.1 highly similar to Bacillus subtilis YbaF protein NP_472078.1 similar to ABC transporter (ATP-binding protein); with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene NP_472079.1 similar to ABC transporter (ATP-binding protein); with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene NP_472081.1 lin2752 NP_472082.1 lin2753 NP_472083.1 is a component of the macrolide binding site in the peptidyl transferase center NP_472084.1 highly similar to RNA polymerase (alpha subunit); catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_472085.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_472086.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_472087.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif NP_472088.1 highly similar to initiation factor IF-I; stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_472089.1 highly similar to adenylate kinases; essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_472090.1 highly similar to preprotein translocase subunit; forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_472091.1 late assembly protein NP_472092.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_472093.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_472094.1 binds 5S rRNA along with protein L5 and L25 NP_472095.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_472096.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_472097.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif NP_472098.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_472099.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_472100.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_472101.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_472102.1 one of the stabilizing components for the large ribosomal subunit NP_472103.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_472104.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_472105.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_472106.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_472107.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_472108.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_472109.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_472110.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_472111.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_472112.1 similar to Bacillus subtilis YbaF protein NP_472113.1 weakly similar to Escherichia coli MenA protein; catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate NP_472114.1 conserved hypothetical lipoprotein NP_472115.1 conserved lipoprotein NP_472116.1 similar to NADH dehydrogenase NP_472117.1 lin2788 NP_472118.1 lin2789 NP_472119.1 similar to heptaprenyl diphosphate synthase component II NP_472120.1 lin2791 NP_472121.1 lin2792 NP_472122.1 lin2793 NP_472123.1 lin2794 NP_472124.1 lin2795 NP_472125.1 similar to creatinine amidohydrolase NP_472126.1 similar to Phosphotriesterase NP_472127.1 similar to hypothetical PTS enzyme IIC component; membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr NP_472128.1 similar to hypothetical PTS enzyme IIB component NP_472129.1 similar to mannitol-specific PTS enzyme IIA component NP_472130.1 similar to transcriptional antiterminator NP_472131.1 highly similar to translation elongation factor EF-Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_472132.1 highly similar to translation elongation factor G; EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_472133.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_472134.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_472135.1 similar to dGTP triphosphohydrolase; dGTPase family type 3 subfamily, presumably hydrolyzes dGTP to deoxyguanosine and triphosphate NP_472136.1 similar to spermidine/spermine N1-acetyl transferase NP_472137.1 similar to ribulose-phosphate 3-epimerase NP_472138.1 similar to transketolase NP_472139.1 similar to ribulose-5-phosphate 3-epimerase NP_472140.1 similar to ribose 5-phosphate epimerase NP_472141.1 similar to polyol dehydrogenase NP_472142.1 similar to sorbitol dehydrogenase NP_472143.1 similar to PTS system galactitol-specific enzyme IIC component NP_472144.1 similar to PTS system galactitol-specific enzyme IIB component NP_472145.1 similar to PTS system galactitol-specific enzyme IIA component NP_472146.1 similar to transcriptional antiterminator (BglG family) NP_472147.1 lin2818 NP_472150.1 similar to ribose 5-phosphate epimerase; catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity NP_472151.1 lin2822 NP_472152.1 similar to UV-damage repair protein NP_472153.1 similar to hydrolase (esterase) (truncated, N-terminal end) NP_472154.1 similar to two components response regulator NP_472155.1 similar to the two components sensor protein kdpD NP_472157.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_472158.1 highly similar to potassium-transporting atpase a chain; catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_472159.1 similar to cellobiose phosphotransferase enzyme IIB component NP_472160.1 similar to cellobiose phosphotransferase enzyme IIC component NP_472161.1 similar to cellobiose phosphotransferase enzyme IIA component NP_472162.1 similar to cell division protein FtsW NP_472163.1 similar to cell division protein FtsW NP_472164.1 highly similar to Mg2+ transport ATPase NP_472165.1 similar to transcription regulator, TetR family NP_472166.1 similar to autolysin, N-acetylmuramidase; cell wall hydrolase; muramidase-2 like protein in Enterococcus faecalis; in Enterococcus faecalis a mutant in this gene has no effect on virulence in mouse models; Listeria monocytogenes MurA in involved in general autolysis; contains an N-terminal muramidase domain and C-terminal LysM repeats for cell wall-anchoring NP_472167.1 lin2839 NP_472168.1 lin2840 NP_472169.1 similar to thymidylate kinase; catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_472170.1 similar to lysine decarboxylase NP_472171.1 similar to dihydroxyacetone kinase; with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase NP_472172.1 similar to hypothetical dihydroxyacetone kinase NP_472173.1 lin2845 NP_472174.1 similar to putative transcription regulator NP_472175.1 similar to conserved hypothetical protein NP_472176.1 similar to aldo/keto reductase NP_472177.1 similar to Bacillus subtilis YaaL protein NP_472178.1 highly similar to recombination protein recR; involved in a recombinational process of DNA repair, independent of the recBC complex NP_472179.1 highly similar to Bacillus subtilis YaaK protein NP_472180.1 highly similar to DNA polymerase III (gamma and tau subunits) NP_472181.1 lin2853 NP_472182.1 lin2854 NP_472183.1 lin2855 NP_472184.1 similar to PTS system, cellobiose-specific enzyme IIC NP_472185.1 lin2857 NP_472186.1 lin2858 NP_472188.1 highly similar to gluconate kinase NP_472191.1 highly similar to ABC transporter (ATP-binding protein) required for expression of cytochrome BD NP_472192.1 highly similar to ABC transporter required for expression of cytochrome BD NP_472193.1 highly similar to cytochrome D ubiquinol oxidase subunit II NP_472194.1 highly similar to cytochrome D ubiquinol oxidase subunit I NP_472196.1 similar to acetate-CoA ligase NP_472197.1 similar to glucosamine-6-phosphate isomerase NP_472198.1 similar to merR-family transcriptional regulator NP_472202.1 similar to transcription regulators NP_472204.1 similar to transcription regulator MerR family NP_472206.1 similar to phosphatase NP_472207.1 similar to transcription regulator (RpiR family) NP_472208.1 similar to transcriptional regulator (LacI family) NP_472209.1 conserved hypothetical protein similar to hypothetical hemolysin NP_472210.1 similar to regulatory proteins of the SIR2 family; Modulates the activities of several enzymes which are inactive in their acetylated form NP_472211.1 lin2883 NP_472212.1 similar to drug-efflux transporters NP_472213.1 lin2885 NP_472214.1 similar to transaldolase; similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity NP_472215.1 weakly similar to transcription regulators CRP/FNR family NP_472216.1 similar to ABC transporter (ATP-binding protein) NP_472217.1 lin2889 NP_472218.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_472219.1 similar to Bacillus subtilis stress protein YdaG NP_472220.1 similar to glutamine amidotransferase NP_472221.1 similar to para-aminobenzoate synthase component I NP_472222.1 similar to ABC transporter, ATP-binding protein NP_472223.1 similar to ABC transporter, ATP-binding protein NP_472224.1 lin2896 NP_472225.1 similar to D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) NP_472226.1 similar to acylase and diesterase NP_472227.1 similar to ATP-dependent DNA helicases NP_472228.1 similar to inosine-monophosphate dehydrogenase NP_472230.1 similar to ABC transporter (ATP-binding protein) NP_472231.1 similar to beta-glucosidase NP_472232.1 similar to PTS cellobiose-specific enzyme IIB NP_472233.1 similar to PTS cellobiose-specific enzyme IIC NP_472234.1 similar to xylose operon regulatory protein and to glucose kinase NP_472235.1 similar to PTS cellobiose-specific enzyme IIA NP_472236.1 similar to hypothetical transcriptional regulator NP_472237.1 lin2910 NP_472238.1 hypothetical membrane protein NP_472239.1 similar to ABC transporter, ATP-binding protein NP_472240.1 similar to gamma-glutamylcysteine synthetase (for the N_terminal part) and to cyanophycin synthetase (C-terminal part); Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine NP_472241.1 similar to ABC transporter, ATP-binding protein NP_472242.1 hypothetical membrane protein NP_472243.1 similar to efflux protein NP_472244.1 lin2917 NP_472245.1 lin2918 NP_472246.1 similar to probable GTP-binding protein; translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_472251.1 lin2924 NP_472252.1 lin2925 NP_472253.1 highly similar to Bacillus subtilis DNA-binding protein Spo0J-like homolog YyaA NP_472254.1 similar to Escherichia coli RpiR transcription regulator NP_472255.1 similar to transcription regulator NP_472256.1 similar to phosphotransferase system mannitol-specific enzyme IIA NP_472257.1 similar to phosphatase NP_472258.1 similar to phosphotransferase system mannitol-specific enzyme IIBC NP_472259.1 similar to dehydrogenase NP_472260.1 similar to a putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate NP_472261.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_472262.1 lin2935 NP_472263.1 lin2936 NP_472264.1 hypothetical secreted protein NP_472265.1 hypothetical secreted protein NP_472266.1 hypothetical secreted protein NP_472267.1 similar to abortive phage resistance mechanism [Lactococcus lactis] NP_472268.1 lin2941 NP_472269.1 highly similar to GidA protein; GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs NP_472270.1 similar to GTPase; in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE NP_472271.1 similar to D-alanyl-D-alanine carboxypeptidase NP_472272.1 lin2945 NP_472273.1 lin2946 NP_472274.1 similar to transcriptional regulator NP_472275.1 similar to reductases; catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_472276.1 similar to transport protein NP_472277.1 similar to peptidases NP_472278.1 similar to transmembrane efflux protein NP_472279.1 similar to carboxypeptidase NP_472281.1 lin2954 NP_472282.1 similar to an hypothetical protein from Thermotoga maritima NP_472283.1 similar to D-3-phosphoglycerate dehydrogenase NP_472284.1 highly similar to phosphoserine aminotransferase; catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine NP_472285.1 similar to efflux proteins (truncated, N-terminal end) NP_472286.1 similar to transcriptional regulator (MarR family) NP_472287.1 lin2961 NP_472288.1 similar to yeast protein Frm2p involved in fatty acid signaling NP_472289.1 similar to thioredoxin NP_472290.1 similar to phosphoglucomutase NP_472292.1 similar to a maltose phosphorylase NP_472293.1 similar to oxidoreductases NP_472294.1 highly similar to an Escherichia coli protein NP_472295.1 similar to alcohol dehydrogenase NP_472296.1 similar to sugar ABC transporter permease protein NP_472297.1 similar to sugar ABC transporter permease protein NP_472298.1 similar to sugar binding protein (ABC transporter) NP_472299.1 similar to Sucrose phosphorylase NP_472300.1 similar to transcriptional regulator NP_472301.1 lin2975 NP_472303.1 similar to transmembrane efflux proteins NP_472304.1 highly similar to Bacillus subtilis YulD protein NP_472305.1 highly similar to rhamnulose-1-phosphate aldolase NP_472306.1 highly similar to L-rhamnose isomerase; catalyzes the formation of L-rhamnulose from L-rhamnose NP_472307.1 similar to rhamnulokinase NP_472308.1 similar to sugar transport proteins NP_472309.1 similar to AraC-type regulatory protein NP_472310.1 lin2984 NP_472311.1 highly similar to Bacillus subtilis Jag protein NP_472312.1 highly similar to Bacillus subtilis SpoIIIJ protein NP_472313.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_472314.1 in Escherichia coli transcription of this gene is enhanced by polyamines NP_569158.1 pli0001; similar to insertion sequence ATP binding protein NP_569159.1 pli0002 NP_569160.1 pli0003; similar to transposase NP_569161.1 pli0004; similar to DNA methylase NP_569162.1 pli0005 NP_569163.1 pli0006 NP_569164.1 pli0007 NP_569165.1 pli0008; similar to unknown protein NP_569166.1 pli0009; similar to unknown protein NP_569167.1 pli0010 NP_569168.1 pli0011; hypothetical gene NP_569170.1 pli0013; similar to unknown protein NP_569171.1 pli0014; similar to unknown protein NP_569172.1 pli0015; similar to plasmid replication protein NP_569173.1 pli0017 NP_569174.1 pli0020; similar to transposase NP_569175.1 pli0021; similar to putative helicase NP_569176.1 pli0022; similar to plasmid replication protein B NP_569177.1 pli0023; similar to plasmid replication initiation protein NP_569178.1 pli0024; similar to transposase NP_569179.1 pli0025; similar to transposase NP_569180.1 pli0026; similar to gram positive plasmid replication B NP_569181.1 pli0027; similar to helicase NP_569183.1 pli0029; similar to DNA methyltransferase NP_569184.1 pli0030 NP_569185.1 pli0031 NP_569187.1 pli0034; similar to arsenical resistance operon repressor NP_569188.1 pli0035; similar to arsenical resistance operon trans-acting ArsD NP_569189.1 pli0036; similar to arsenical resistance operon repressor NP_569190.1 pli0037; similar to arsenical pump-driving ATPase NP_569191.1 pli0038; similar to possible arsenic resistance membrane protein ArsB NP_569192.1 pli0039; similar to heavy metal membrane efflux protein NP_569193.1 pli0040; similar to flavoprotein oxidoreductase NP_569194.1 pli0041; similar to ABC transporter ATP-binding protein ; hypothetical start NP_569195.1 pli0042; Similar to transposase, N-terminal part NP_569197.1 pli0044; similar to NADH peroxidase NP_569199.1 pli0046 NP_569200.1 pli0047 NP_569201.1 pli0048; similar to heavy metal-transporting ATPase NP_569203.1 pli0050; similar to the two components sensor protein kdpD NP_569204.1 pli0051; similar to the two components response regulator KdpE NP_569205.1 pli0052; catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_569206.1 pli0053; One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_569207.1 pli0054 NP_569208.1 pli0055; one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex NP_569209.1 pli0056; similar to resolvase/integrase NP_569210.1 pli0057; similar to DNA transposition protein NP_569211.1 pli0058; similar to transposase NP_569212.1 pli0059; similar to invertase NP_569213.1 pli0060; similar to cadmium resistance accessory protein NP_569214.1 pli0061; similar to cadmium-transporting ATPase NP_569215.1 pli0062; similar to unknown protein NP_569216.1 pli0063; similar to transposase NP_569217.1 pli0064; similar to unknown protein NP_569218.1 pli0065 NP_569219.1 pli0066 NP_569220.1 pli0067; similar to UV-damage repair protein NP_569221.1 pli0068; similar to unknown protein NP_569222.1 pli0069; similar to plasmid copy control protein repB NP_569223.1 pli0070; similar to plasmid replication protein NP_569224.1 pli0071; similar to transposase NP_569225.1 pli0072; similar to transposase NP_569226.1 pli0073 NP_569227.1 pli0074 NP_569228.1 pli0075 NP_569230.1 pli0077; similar to transposase N-terminal part NP_569231.1 pli0079; similar to Na+/H+ antiporter NP_569232.1 pli0080