-- dump date 20120504_151801 -- class Genbank::CDS -- table cds_note -- id note YP_004462047.1 COGs: COG0593 ATPase involved in DNA replication initiation; InterPro IPR003593: IPR013159: IPR001957: IPR013317: IPR 018312: IPR020591; KEGG: cbh:CLC_0001 chromosomal replication initiation protein; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: Chromosomal replication initiator DnaA domain; AAA ATPase; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA YP_004462048.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: aoe:Clos_0002 DNA polymerase III subunit beta; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit YP_004462049.1 COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); InterPro IPR001238: IPR003395: IPR018078; KEGG: cce:Ccel_0004 DNA replication and repair protein RecF; PFAM: SMC domain protein; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA replication and repair protein RecF; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein YP_004462050.1 KEGG: tpd:Teth39_0005 hypothetical protein; SPTR: uncharacterized protein YP_004462051.1 COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594: IPR001241: IPR011557: IPR013506: IPR 006171: IPR002288: IPR018522: IPR000565; KEGG: tpd:Teth39_0010 DNA gyrase subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: DNA topoisomerase IV, B subunit; TIGRFAM: DNA gyrase, B subunit; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit YP_004462052.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR003646: IPR013247: IPR000064; KEGG: tmt:Tmath_0856 NLP/P60 protein; PFAM: NLP/P60 protein; SH3 type 3 domain protein; SMART: SH3 domain protein; SPTR: NLP/P60 protein; PFAM: NlpC/P60 family; Bacterial SH3 domain YP_004462053.1 COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205: IPR005743: IPR006691; KEGG: tte:TTE0011 DNA gyrase (topoisomerase II) A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: DNA gyrase (Topoisomerase II) A subunit; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase, A subunit YP_004462054.1 COGs: COG2703 Hemerythrin; InterPro IPR012827: IPR012312: IPR016131; KEGG: csc:Csac_0461 hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein; SPTR: Hemerythrin-like metal-binding protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain YP_004462055.1 KEGG: dsy:DSY3041 hypothetical protein; SPTR: uncharacterized protein YP_004462056.1 KEGG: pan:PODANSg5523 hypothetical protein; SPTR: Predicted CDS Pa_7_11170; PFAM: FHIPEP family YP_004462057.1 KEGG: mma:MM_1676 hypothetical protein; SPTR: uncharacterized protein YP_004462058.1 COGs: COG2247 cell wall-binding domain; InterPro IPR007253; KEGG: clj:CLJU_c18660 cell wall-binding protein; PFAM: cell wall binding repeat 2-containing protein; SPTR: uncharacterized protein; PFAM: cell wall binding repeat 2 YP_004462059.1 KEGG: bbe:BBR47_53590 hypothetical protein; SPTR: uncharacterized protein YP_004462060.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000524: IPR001761; KEGG: gym:GYMC10_2719 transcriptional regulator, GntR family with LacI sensor; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; family YP_004462061.1 COGs: COG0383 Alpha-mannosidase; InterPro IPR000602: IPR015341: IPR011682; KEGG: ttr:Tter_1503 glycoside hydrolase 38; PFAM: glycoside hydrolase 38; Glycoside hydrolase 38 central region; glycosyl hydrolase 38 domain protein; PRIAM: Alpha-mannosidase; SPTR: Glycoside hydrolase 38; PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain; Alpha mannosidase, middle domain YP_004462062.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tmt:Tmath_1701 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462063.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tpd:Teth39_0613 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein, family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462064.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ttr:Tter_0507 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462065.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ttr:Tter_2216 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462066.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: dth:DICTH_1484 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004462067.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ate:Athe_0175 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462068.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: dtu:Dtur_1592 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462069.1 InterPro IPR013026: IPR013017: IPR001258; KEGG: ppp:PHYPADRAFT_104352 hypothetical protein; PFAM: NHL repeat containing protein; SPTR: Predicted protein; PFAM: NHL repeat YP_004462070.1 KEGG: dtu:Dtur_1590 hypothetical protein; SPTR: uncharacterized protein YP_004462071.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: dtu:Dtur_1589 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462072.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: dth:DICTH_1478 transport protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: transport protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462073.1 KEGG: ote:Oter_2886 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004462074.1 COGs: COG3408 Glycogen debranching protein; KEGG: bbe:BBR47_58010 hypothetical protein; SPTR: uncharacterized protein; PFAM: Trehalase YP_004462075.1 KEGG: bfo:BRAFLDRAFT_97256 hypothetical protein; SPTR: uncharacterized protein YP_004462076.1 COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060: IPR013096: IPR000005; KEGG: cbe:Cbei_4840 helix-turn-helix domain-containing protein; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: Helix-turn-helix-domain containing protein, AraC type; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain YP_004462077.1 KEGG: dol:Dole_2957 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004462078.1 COGs: COG0383 Alpha-mannosidase; InterPro IPR000602: IPR015341: IPR011682; KEGG: tpd:Teth39_0612 alpha-mannosidase; PFAM: glycosyl hydrolase 38 domain protein; glycoside hydrolase 38; Glycoside hydrolase 38 central region; PRIAM: Alpha-mannosidase; SPTR: Alpha-mannosidase; PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain; Alpha mannosidase, middle domain YP_004462079.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR010161: IPR002933: IPR011650: IPR001261; KEGG: tex:Teth514_1206 peptidase T; PFAM: peptidase dimerisation domain protein; peptidase M20; PRIAM: Tripeptide aminopeptidase; SPTR: Peptidase T; TIGRFAM: peptidase T; PFAM: Peptidase M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: peptidase T YP_004462080.1 InterPro IPR000182; KEGG: fno:Fnod_1042 GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004462081.1 InterPro IPR001845; KEGG: cce:Ccel_1143 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family YP_004462082.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase YP_004462083.1 COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: tte:TTE0252 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Glutaconyl-CoA decarboxylase; SPTR: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit YP_004462084.1 KEGG: sub:SUB1590 membrane protein; SPTR: membrane protein; PFAM: Oxaloacetate decarboxylase, gamma chain YP_004462085.1 COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: hmo:HM1_2673 hypothetical protein; PFAM: type III effector Hrp-dependent outers; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF1537 YP_004462086.1 COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: hmo:HM1_2672 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase YP_004462087.1 COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase; InterPro IPR001670: IPR018211; KEGG: cth:Cthe_0101 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase YP_004462088.1 COGs: COG0009 translation factor (SUA5); InterPro IPR004388: IPR006070: IPR005145: IPR010923; KEGG: cce:Ccel_0257 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SUA5 domain-containing protein; SPTR: Sua5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; SUA5 domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004462089.1 COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867: IPR000106; KEGG: aoe:Clos_2574 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_004462090.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660: IPR004089: IPR004010; KEGG: tte:TTE0702 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis protein signaling domain protein; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004462091.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: mta:Moth_0269 beta-lactamase-like; SPTR: Beta-lactamase-like; PFAM: Metallo-beta-lactamase superfamily YP_004462092.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: bpf:BpOF4_06575 UDP-galactose phosphate transferase; PFAM: sugar transferase; SPTR: UDP-galactose phosphate transferase; PFAM: Bacterial sugar transferase YP_004462093.1 InterPro IPR006199; KEGG: ate:Athe_2440 transcriptional repressor, LexA family; PFAM: LexA DNA-binding domain protein; SPTR: LexA DNA binding domain protein; PFAM: LexA DNA binding domain YP_004462094.1 KEGG: ahe:Arch_0524 hypothetical protein; SPTR: uncharacterized protein YP_004462095.1 KEGG: ddi:DDB_G0267488 hypothetical protein; SPTR: Agarase YP_004462097.1 KEGG: tit:Thit_1370 hypothetical protein; SPTR: uncharacterized protein YP_004462098.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508: IPR007730; KEGG: gct:GC56T3_0290 cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin; Sporulation domain-containing protein; SMART: cell wall hydrolase/autolysin; SPTR: uncharacterized protein; PFAM: N-acetylmuramoyl-L-alanine amidase; Sporulation related domain YP_004462099.1 KEGG: cth:Cthe_2497 hypothetical protein; SPTR: uncharacterized protein YP_004462100.1 COGs: COG3858 glycosyl hydrolase; InterPro IPR011583; KEGG: cce:Ccel_2820 hypothetical protein; SMART: chitinase II; SPTR: Glycosyl hydrolase-like protein; manually curated YP_004462101.1 KEGG: tit:Thit_1373 hypothetical protein; SPTR: uncharacterized protein YP_004462102.1 KEGG: hmo:HM1_2972 hypothetical protein; SPTR: uncharacterized protein YP_004462103.1 COGs: COG4926 Phage-related protein; InterPro IPR007119; KEGG: hmo:HM1_2871 phage minor structural protein, N-terminal; SPTR: Phage minor structural protein; TIGRFAM: phage minor structural protein; PFAM: Protein of unknown function (DUF1142); TIGRFAM: phage minor structural protein, N-terminal region YP_004462104.1 KEGG: azl:AZL_b01120 hypothetical protein; SPTR: uncharacterized protein YP_004462105.1 KEGG: tit:Thit_1377 phage tail component; SPTR: Phage tail component; PFAM: Phage tail protein; TIGRFAM: phage tail component, N-terminal domain YP_004462106.1 COGs: COG5280 Phage-related minor tail protein; InterPro IPR010090: IPR019775; KEGG: afl:Aflv_0673 phage-related tail protein; PFAM: tail tape measure protein TP901 core region; SPTR: Phage-related tail protein; TIGRFAM: phage tail tape measure protein, TP901 family; PFAM: Phage-related minor tail protein; TIGRFAM: phage tail tape measure protein, TP901 family, core region YP_004462107.1 KEGG: tit:Thit_1380 hypothetical protein; SPTR: uncharacterized protein YP_004462108.1 KEGG: tit:Thit_1381 hypothetical protein; SPTR: uncharacterized protein YP_004462110.1 KEGG: tit:Thit_1382 hypothetical protein; SPTR: uncharacterized protein YP_004462111.1 KEGG: tit:Thit_1383 hypothetical protein; SPTR: uncharacterized protein YP_004462112.1 KEGG: tit:Thit_1384 phage head-tail adaptor; SPTR: Phage head-tail adaptor YP_004462113.1 KEGG: tit:Thit_1385 hypothetical protein; SPTR: uncharacterized protein YP_004462114.1 KEGG: dae:Dtox_4235 hypothetical protein; SPTR: uncharacterized protein YP_004462115.1 KEGG: ckr:CKR_1729 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2190) YP_004462116.1 KEGG: tit:Thit_1389 hypothetical protein; SPTR: uncharacterized protein YP_004462117.1 KEGG: dae:Dtox_4233 hypothetical protein; SPTR: uncharacterized protein YP_004462118.1 KEGG: tit:Thit_1390 hypothetical protein; SPTR: uncharacterized protein YP_004462119.1 KEGG: tet:TTHERM_00535160 hypothetical protein; SPTR: GF12970 YP_004462120.1 KEGG: tit:Thit_1393 hypothetical protein; SPTR: uncharacterized protein YP_004462121.1 KEGG: tit:Thit_1394 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage portal protein, SPP1 Gp6-like YP_004462122.1 KEGG: tit:Thit_1395 hypothetical protein; SPTR: uncharacterized protein YP_004462123.1 KEGG: tit:Thit_1396 hypothetical protein; SPTR: uncharacterized protein YP_004462124.1 KEGG: bwe:BcerKBAB4_3435 hypothetical protein; SPTR: uncharacterized protein YP_004462125.1 KEGG: bwe:BcerKBAB4_3436 hypothetical protein; SPTR: uncharacterized protein YP_004462126.1 InterPro IPR013249; KEGG: dfe:Dfer_2829 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70, region 4 YP_004462127.1 KEGG: cmi:pCM2_0038 hypothetical protein YP_004462128.1 COGs: COG3331 Penicillin-binding protein-related factor A recombinase; InterPro IPR004612; KEGG: chy:CHY_1684 prophage LambdaCh01, recombination protein U; PFAM: Recombination protein U; SPTR: Prophage LambdaCh01, recombination protein U; PFAM: Recombination protein U; TIGRFAM: recombination protein U YP_004462129.1 KEGG: ate:Athe_2442 hypothetical protein; SPTR: uncharacterized protein YP_004462130.1 KEGG: gfo:GFO_2634 two-component system sensor histidine kinase; SPTR: Two-component system sensor histidine kinase YP_004462131.1 KEGG: cba:CLB_2468 hypothetical protein; SPTR: uncharacterized protein; PFAM: Loader and inhibitor of phage G40P YP_004462132.1 KEGG: vcj:VCD_003663 hypothetical protein; SPTR: uncharacterized protein YP_004462134.1 KEGG: cth:Cthe_2464 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacteriophage Mu Gam like protein YP_004462135.1 KEGG: cth:Cthe_2465 hypothetical protein; SPTR: uncharacterized protein YP_004462136.1 KEGG: ath:AT3G12150 hypothetical protein YP_004462137.1 KEGG: gga:395695 A kinase (PRKA) anchor protein (yotiao) 9; SPTR: Chromosome 3 SCAF15050, whole genome shotgun sequence. YP_004462138.1 InterPro IPR010093; KEGG: cth:Cthe_2463 DNA binding domain-containing protein; SPTR: DNA binding domain, excisionase; TIGRFAM: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004462139.1 SPTR: DNA gyrase, B subunit YP_004462140.1 KEGG: dma:DMR_28850 hypothetical membrane protein; SPTR: Hypothetical membrane protein YP_004462141.1 KEGG: smd:Smed_4773 hypothetical protein; SPTR: uncharacterized protein YP_004462142.1 KEGG: asa:ASA_0522 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; SPTR: uncharacterized protein YP_004462143.1 InterPro IPR001387; KEGG: cth:Cthe_2461 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix YP_004462144.1 InterPro IPR001387; KEGG: tit:Thit_1413 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix YP_004462145.1 KEGG: tit:Thit_1414 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF955) YP_004462146.1 COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR006055: IPR006054: IPR013520; KEGG: ctc:CTC01271 DNA polymerase III PolC; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: DNA polymerase III polC-type; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family YP_004462147.1 KEGG: csc:Csac_1015 hypothetical protein; SPTR: uncharacterized protein YP_004462148.1 KEGG: ace:Acel_1105 amino acid permease-associated region; SPTR: uncharacterized protein YP_004462149.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: cth:Cthe_2455 phage integrase; PFAM: integrase; SPTR: Phage integrase; PFAM: Phage integrase YP_004462150.1 COGs: COG0004 Ammonia permease; InterPro IPR001905: IPR018047; KEGG: tjr:TherJR_0702 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter YP_004462151.1 KEGG: bca:BCE_1868 hypothetical protein; SPTR: Acetyltransferase and hydrolase with the alpha/beta hydrolase fold; PFAM: Lecithin:cholesterol acyltransferase YP_004462152.1 COGs: COG4552 acetyltransferase involved in intracellular survival and related acetyltransferase; KEGG: gym:GYMC10_2630 GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase YP_004462153.1 COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027; KEGG: chy:CHY_2596 nitrate reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004462154.1 COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cpo:COPRO5265_0064 ZIP zinc transporter family protein; PFAM: zinc/iron permease; SPTR: Zinc/iron permease; PFAM: ZIP Zinc transporter YP_004462155.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155: IPR013027: IPR000103; KEGG: mta:Moth_2056 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase YP_004462156.1 KEGG: ske:Sked_32660 glycosyl transferase; SPTR: Glycosyl transferase YP_004462157.1 COGs: COG5337 Spore coat assembly protein; InterPro IPR014867; KEGG: cce:Ccel_0251 spore coat protein CotH; PFAM: Spore coat protein CotH; SPTR: Spore coat protein CotH; PFAM: CotH protein YP_004462158.1 KEGG: cce:Ccel_0250 hypothetical protein; SPTR: uncharacterized protein YP_004462159.1 InterPro IPR018966; KEGG: swo:Swol_2178 hypothetical protein; PFAM: VTC domain; SPTR: uncharacterized protein; PFAM: VTC domain YP_004462160.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: cce:Ccel_0247 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004462161.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cce:Ccel_0246 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004462162.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: clj:CLJU_c01270 sugar ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Ribose transport ATP-binding protein RbsA; PFAM: ABC transporter YP_004462163.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034: IPR014036: IPR018356; KEGG: csc:Csac_0239 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004462164.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593: IPR003439: IPR015861: IPR017871; KEGG: csc:Csac_0240 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004462165.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ate:Athe_2265 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: Monosaccharide-transporting ATPase; PFAM: Branched-chain amino acid transport system / permease component YP_004462166.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: tit:Thit_1705 periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family YP_004462167.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR003594: IPR005467: IPR010559: IPR 004358; KEGG: pjd:Pjdr2_1932 histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462168.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR018060: IPR000005; KEGG: ate:Athe_2055 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain YP_004462169.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: csc:Csac_1357 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462170.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csc:Csac_1358 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462171.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ate:Athe_2052 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462172.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2093 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462173.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2092 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462174.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ate:Athe_2091 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462175.1 InterPro IPR013517; KEGG: cce:Ccel_0739 cellulosome protein dockerin type I; PFAM: FG-GAP repeat protein; SPTR: Cellulosome protein dockerin type I YP_004462176.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR018060: IPR000005; KEGG: cbe:Cbei_4962 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004462177.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR005467: IPR003660: IPR010559: IPR003594; KEGG: gym:GYMC10_4333 integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_004462178.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4337 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462179.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ate:Athe_2080 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462180.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_3535 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462181.1 InterPro IPR001584; KEGG: tjr:TherJR_2621 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004462182.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005: IPR018062: IPR020449; KEGG: gym:GYMC10_2461 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004462183.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2462 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462184.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462185.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4530 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462186.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515: IPR001000; KEGG: lin:lin0218 hypothetical protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Lmo0179 protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462187.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: kol:Kole_1036 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462188.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ttr:Tter_2218 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462189.1 COGs: COG3533 conserved hypothetical protein; InterPro IPR012878; KEGG: tmt:Tmath_1689 protein of unknown function DUF1680; PFAM: protein of unknown function DUF1680; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase of unknown function (DUF1680) YP_004462190.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005: IPR018062: IPR020449; KEGG: cbe:Cbei_2362 helix-turn-helix domain-containing protein; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004462192.1 COGs: COG3459 Cellobiose phosphorylase; InterPro IPR009342: IPR010383: IPR010403; KEGG: cth:Cthe_0275 cellobiose phosphorylase; PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; SPTR: Cellobiose phosphorylase; PFAM: Glycosyltransferase 36; carbohydrate binding domain; Glycosyltransferase 36 associated family YP_004462193.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR004429: IPR001804: IPR019818; KEGG: amt:Amet_3455 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase YP_004462194.1 COGs: COG1827 small molecule binding protein (contains 3H domain); InterPro IPR004173; KEGG: tte:TTE0520 hypothetical protein; PFAM: 3H domain-containing protein; SPTR: uncharacterized protein; PFAM: HTH domain; 3H domain YP_004462195.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: gym:GYMC10_4545 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004462196.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611: IPR002173: IPR002139; KEGG: tpd:Teth39_1972 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase YP_004462197.1 KEGG: cth:Cthe_2069 hypothetical protein; SPTR: uncharacterized protein YP_004462198.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587; KEGG: bha:BH0491 hypothetical protein; PFAM: creatinase; SPTR: Peptidase M24; PFAM: Metallopeptidase M24; Creatinase/Prolidase N-terminal domain YP_004462199.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cth:Cthe_2306 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004462200.1 COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR006349: IPR006357: IPR005834; KEGG: cbe:Cbei_2502 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: Sugar phosphatase NagD; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily subfamily IIA hydrolase, TIGR01457; phosphoglycolate/pyridoxal phosphate phosphatase; Haloacid Dehalogenase Superfamily Class (subfamily) IIA YP_004462201.1 COGs: COG4277 DNA-binding protein with the Helix-hairpin-helix motif; InterPro IPR006638: IPR007197; KEGG: tjr:TherJR_1012 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004462202.1 InterPro IPR019045; KEGG: coc:Coch_0686 type II restriction endonuclease TdeIII; PFAM: Restriction endonuclease, type II, MjaII; SPTR: Type II restriction endonuclease TdeIII; PFAM: MjaII restriction endonuclease YP_004462203.1 InterPro IPR002941; KEGG: cts:Ctha_1153 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase YP_004462204.1 InterPro IPR011701: IPR005829; KEGG: bpf:BpOF4_19135 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Nucleoside H+ symporter; TIGRFAM: oligosaccharide:H+ symporter YP_004462205.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593: IPR012763: IPR003959; KEGG: tjr:TherJR_0068 DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: ATPase associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunit gamma and tau YP_004462206.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: tmt:Tmath_0373 glycoside hydrolase 4; PFAM: glycoside hydrolase 4; SPTR: Glycoside hydrolase, family 4; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004462207.1 COGs: COG0718 conserved hypothetical protein; InterPro IPR004401; KEGG: tpd:Teth39_2199 hypothetical protein; PFAM: Uncharacterised protein family UPF0133; SPTR: UPF0133 protein TtheDRAFT_2621; PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: DNA-binding protein, YbaB/EbfC family YP_004462208.1 COGs: COG0353 Recombinational DNA repair protein (RecF pathway); InterPro IPR003583: IPR006154: IPR000093: IPR015967: IPR 006171; KEGG: hmo:HM1_0809 recombination protein RecR; PFAM: TOPRIM domain-containing protein; Zinc finger C4-type, RecR; SMART: Toprim sub domain-containing protein; Helix-hairpin-helix DNA-binding class 1; SPTR: Recombination protein recR; TIGRFAM: recombination protein RecR; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_004462209.1 KEGG: aoe:Clos_2803 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2508) YP_004462210.1 InterPro IPR010001; KEGG: amt:Amet_4774 sigmaK-factor processing regulatory BofA; PFAM: sigmaK-factor processing regulatory BofA; SPTR: SigmaK-factor processing regulatory BofA; TIGRFAM: pro-sigmaK processing inhibitor BofA; PFAM: SigmaK-factor processing regulatory protein BofA; TIGRFAM: pro-sigmaK processing inhibitor BofA YP_004462211.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524: IPR011663; KEGG: cpf:CPF_2963 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004462212.1 COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: lsp:Bsph_1258 glucosamine--fructose-6-phosphate aminotransferase (isomerizing); PFAM: sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glutamine--fructose-6-phosphate transaminase (Isomerizing); PFAM: SIS domain YP_004462213.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: sli:Slin_1003 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; PRIAM: Alpha-N-acetylgalactosaminidase; SPTR: Oxidoreductase, Gfo/Idh/MocA family; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004462214.1 KEGG: dth:DICTH_1894 hypothetical protein; SPTR: uncharacterized protein YP_004462215.1 COGs: COG0371 Glycerol dehydrogenase; InterPro IPR002658; KEGG: tit:Thit_1700 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); SPTR: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase YP_004462216.1 COGs: COG0213 Thymidine phosphorylase; InterPro IPR018090: IPR017459: IPR000312: IPR013102: IPR 017872: IPR000053; KEGG: tit:Thit_0437 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: Pyrimidine-nucleoside phosphorylase; SPTR: Pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase YP_004462217.1 InterPro IPR003838; KEGG: csc:Csac_0506 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004462218.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593: IPR003439; KEGG: csc:Csac_0507 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; TIGRFAM: bacteriocin export ABC transporter, lactococcin 972 group YP_004462219.1 InterPro IPR006442; KEGG: lba:Lebu_1178 prevent-host-death family protein; SPTR: Toxin-antitoxin system, antitoxin component, PHD family; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004462220.1 COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: swo:Swol_0432 hypothetical protein; PFAM: Addiction module toxin Txe/YoeB; SPTR: uncharacterized protein; TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family YP_004462221.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594: IPR005467: IPR004358; KEGG: csc:Csac_0508 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462222.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: csc:Csac_0509 two component transcriptional regulator; PFAM: transcriptional regulator domain-containing protein; response regulator receiver; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004462223.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_4789 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein, family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462224.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4788 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462225.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4787 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462226.1 COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: hor:Hore_20580 glycoside hydrolase 43; PFAM: glycoside hydrolase 43; SPTR: Glycoside hydrolase; PFAM: Glycosyl hydrolases family 43 YP_004462227.1 KEGG: bth:BT_3954 hypothetical protein; SPTR: uncharacterized protein YP_004462228.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: pjd:Pjdr2_3587 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004462229.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104: IPR006103; KEGG: gtn:GTNG_0407 hydrolase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 TIM barrel; SPTR: hydrolase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain YP_004462230.1 COGs: COG3534 Alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: gct:GC56T3_1627 alpha-L-arabinofuranosidase domain protein; PFAM: alpha-L-arabinofuranosidase domain protein; PRIAM: Alpha-N-arabinofuranosidase; SMART: alpha-L-arabinofuranosidase domain protein; SPTR: Alpha-L-arabinofuranosidase domain protein; PFAM: Alpha-L-arabinofuranosidase C-terminus YP_004462231.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: blj:BLD_1301 MalE-type ABC sugar transport system periplasmic component; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transport system; PFAM: Bacterial extracellular solute-binding protein YP_004462232.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: esi:Exig_0373 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462233.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: esi:Exig_0374 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462234.1 InterPro IPR001584; KEGG: tjr:TherJR_2644 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004462235.1 KEGG: tva:TVAG_257510 hypothetical protein; SPTR: uncharacterized protein YP_004462236.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003660: IPR010559: IPR003594: IPR004358; KEGG: bha:BH2110 hypothetical protein; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: BH2110 protein; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462237.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR018060: IPR000005: IPR018062: IPR 020449; KEGG: ate:Athe_0853 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004462238.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cce:Ccel_0150 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462239.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_5315 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462240.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_0900 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport system inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462241.1 COGs: COG3405 Endoglucanase Y; InterPro IPR002037; KEGG: cce:Ccel_1258 glycoside hydrolase 8; PFAM: glycoside hydrolase 8; SPTR: Glycoside hydrolase 8; PFAM: Glycosyl hydrolases family 8 YP_004462242.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104: IPR006103; KEGG: gtn:GTNG_0407 hydrolase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 TIM barrel; SPTR: hydrolase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain YP_004462243.1 InterPro IPR002934; KEGG: tmt:Tmath_0293 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain YP_004462244.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: hor:Hore_04560 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; PFAM: HIT domain YP_004462245.1 KEGG: tva:TVAG_466250 hypothetical protein; SPTR: uncharacterized protein YP_004462246.1 KEGG: cbg:CbuG_0193 hypothetical protein; SPTR: uncharacterized protein YP_004462247.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310: IPR019808; KEGG: cbi:CLJ_B2118 HIT family protein; PFAM: histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; PFAM: HIT domain YP_004462248.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001: IPR001650: IPR014021: IPR006935; KEGG: ctc:CTC00657 DNA/RNA helicase; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DNA/RNA helicase; PFAM: NgoFVII restriction endonuclease; Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit YP_004462249.1 KEGG: mev:Metev_1205 hypothetical protein; SPTR: uncharacterized protein YP_004462250.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: hor:Hore_15330 methylamine-specific methylcobalamin coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Methylamine-specific methylcobalamin coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family YP_004462251.1 COGs: COG0523 GTPase (G3E family); InterPro IPR003495; KEGG: hor:Hore_15320 cobalamin synthesis protein P47K; PFAM: cobalamin synthesis protein P47K; SPTR: Cobalamin synthesis protein/P47K; PFAM: CobW/HypB/UreG, nucleotide-binding domain YP_004462252.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005785: IPR001544: IPR018300; KEGG: ate:Athe_0664 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: D-amino-acid transaminase; SPTR: Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: D-amino acid aminotransferase; branched-chain amino acid aminotransferase, group I YP_004462253.1 COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR004404: IPR000581: IPR020558; KEGG: cth:Cthe_2713 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase; TIGRFAM: dihydroxy-acid dehydratase YP_004462254.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: ckr:CKR_0654 hypothetical protein; PFAM: Phosphoglycerate mutase; SPTR: uncharacterized protein; PFAM: Phosphoglycerate mutase; TIGRFAM: alpha-ribazole phosphatase YP_004462255.1 KEGG: tmt:Tmath_1773 hypothetical protein; SPTR: uncharacterized protein YP_004462256.1 KEGG: tex:Teth514_0744 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3006) YP_004462257.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740: IPR019264; KEGG: tpd:Teth39_1269 hypothetical protein; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; manually curated; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004462258.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: cce:Ccel_3209 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide repeat YP_004462259.1 COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: slp:Slip_2351 protein of unknown function DUF951; PFAM: protein of unknown function DUF951; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951) YP_004462260.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764: IPR006680: IPR000318; KEGG: tmt:Tmath_0287 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_004462261.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR004488: IPR002523; KEGG: cpo:COPRO5265_1480 magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; SPTR: Magnesium and cobalt transport protein CorA; TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA) YP_004462262.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: ere:EUBREC_2883 hypothetical oxidoreductase YdgJ; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004462263.1 COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502: IPR005122; KEGG: sth:STH940 G/U mismatch-specific DNA glycosylase; PFAM: ADP-ribosylation/Crystallin J1; Uracil-DNA glycosylase superfamily; SPTR: G/U mismatch-specific DNA glycosylase; PFAM: ADP-ribosylglycohydrolase; Uracil DNA glycosylase superfamily; TIGRFAM: mismatch-specific thymine-DNA glycosylate (mug) YP_004462264.1 COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: afw:Anae109_0642 ferredoxin; PFAM: ferredoxin; SPTR: Ferredoxin protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain YP_004462265.1 COGs: COG0172 Seryl-tRNA synthetase; InterPro IPR002317: IPR006195: IPR015866: IPR002314: IPR 018156; KEGG: cth:Cthe_2381 seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like; PRIAM: Serine--tRNA ligase; SPTR: Seryl-tRNA synthetase; TIGRFAM: seryl-tRNA synthetase; PFAM: tRNA synthetase class II core domain (G, H, P, S and T); Seryl-tRNA synthetase N-terminal domain; TIGRFAM: seryl-tRNA synthetase YP_004462266.1 COGs: COG1073 Hydrolase of the alpha/beta superfamily; KEGG: csc:Csac_1229 alpha/beta fold family hydrolase-like protein; SPTR: Hydrolase of the alpha/beta superfamily-like protein; PFAM: Prolyl oligopeptidase YP_004462267.1 COGs: COG2247 cell wall-binding domain; InterPro IPR007253; KEGG: bbe:BBR47_54110 hypothetical protein; PFAM: cell wall binding repeat 2-containing protein; SPTR: SgtA; PFAM: cell wall binding repeat 2 YP_004462268.1 KEGG: ctc:CTC00260 N-acetylmuramoyl-L-alanine amidase; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: Copper resistance protein CopC YP_004462269.1 KEGG: dre:798921 si:ch211-217k17.9; SPTR: uncharacterized protein YP_004462270.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR011583: IPR000209: IPR007280: IPR001223: IPR 007253; KEGG: tjr:TherJR_2324 peptidase S8 and S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; peptidase domain protein; glycoside hydrolase 18; cell wall binding repeat 2-containing protein; SMART: chitinase II; SPTR: Peptidase S8 and S53 subtilisin kexin sedolisin; PFAM: cell wall binding repeat 2; Glycosyl hydrolases family 18; Bacterial pre-peptidase C-terminal domain; Subtilase YP_004462271.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593: IPR003439: IPR017940: IPR001140: IPR 017871; KEGG: csc:Csac_2201 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter transmembrane region YP_004462272.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593: IPR003439: IPR017940: IPR001140: IPR 017871; KEGG: csc:Csac_2202 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter YP_004462273.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: cpi:Cpin_2228 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004462274.1 KEGG: ate:Athe_0168 transcriptional regulator, CopG family; SPTR: transcriptional regulator, CopG family YP_004462275.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197: IPR010722: IPR018506; KEGG: slp:Slip_0120 biotin and thiamin synthesis associated; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Biotin and thiamin synthesis associated; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH YP_004462276.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR012318: IPR001808; KEGG: cpy:Cphy_3149 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SPTR: cAMP-binding proteins-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; PFAM: Cyclic nucleotide-binding domain YP_004462277.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010048: IPR004137; KEGG: pth:PTH_0779 hydroxylamine reductase; PFAM: Prismane; SPTR: Hydroxylamine reductase; TIGRFAM: hybrid cluster protein; PFAM: Prismane/CO dehydrogenase; TIGRFAM: hydroxylamine reductase YP_004462278.1 InterPro IPR001584; KEGG: tjr:TherJR_2621 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004462279.1 COGs: COG0254 Ribosomal protein L31; InterPro IPR002150; KEGG: tit:Thit_0122 ribosomal protein L31; PFAM: ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_004462280.1 COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: tmt:Tmath_0181 protein of unknown function DUF1385; PFAM: protein of unknown function DUF1385; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1385) YP_004462281.1 COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR004556: IPR019874: IPR007848: IPR002052; KEGG: tmt:Tmath_0182 protein-(glutamine-N5) methyltransferase, release factor-specific; PFAM: methyltransferase small; SPTR: Similar to protein methyltransferase; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; modification methylase, HemK family; PFAM: Methyltransferase small domain; TIGRFAM: HemK family methylases; protein-(glutamine-N5) methyltransferase, release factor-specific YP_004462282.1 COGs: COG0216 Protein chain release factor A; InterPro IPR004373: IPR005139: IPR000352; KEGG: ctc:CTC00302 peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; SPTR: Peptide chain release factor 1; TIGRFAM: peptide chain release factor 1; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1 YP_004462283.1 COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: hau:Haur_3439 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; SPTR: Sodium/hydrogen exchanger; PFAM: Sodium/hydrogen exchanger family YP_004462284.1 KEGG: aoe:Clos_2092 hypothetical protein; SPTR: uncharacterized protein YP_004462285.1 KEGG: aco:Amico_0798 hypothetical protein; SPTR: uncharacterized protein YP_004462286.1 KEGG: bcl:ABC4042 transcriptional regulator; SPTR: Arylsulfotransferase YP_004462287.1 COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: tex:Teth514_0095 zinc/iron permease; PFAM: zinc/iron permease; SPTR: Zinc/iron permease; PFAM: ZIP Zinc transporter YP_004462288.1 KEGG: gga:426042 splicing factor 3b, subunit 4, 49kDa; SPTR: SF3B4 protein YP_004462289.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500: IPR004785; KEGG: clj:CLJU_c02310 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose 5-phosphate isomerase RpiB; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004462290.1 COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR005765: IPR000836; KEGG: cth:Cthe_2598 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase YP_004462291.1 COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR004680: IPR000802; KEGG: drm:Dred_1987 citrate transporter; PFAM: Citrate transporter; SPTR: Possible tyrosine transporter P-protein (TC 2.A.45.2.1); PFAM: Citrate transporter YP_004462292.1 COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125: IPR016192: IPR016473; KEGG: chy:CHY_2556 ComE operon protein 2; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: comE operon protein 2; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004462293.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: tit:Thit_0133 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004462294.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR011289; KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; class II aldolase, tagatose bisphosphate family; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist YP_004462295.1 COGs: COG0176 Transaldolase; InterPro IPR004731: IPR001585: IPR018225; KEGG: ate:Athe_1489 translaldolase; PFAM: Transaldolase; SPTR: Transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family YP_004462296.1 COGs: COG1158 Transcription termination factor; InterPro IPR011129: IPR003593: IPR004665: IPR011112: IPR 011113: IPR000194: IPR018936; KEGG: cth:Cthe_2174 transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; Rho termination factor RNA-binding; Rho termination factor domain protein; SMART: Cold shock protein; AAA ATPase; SPTR: Transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: Rho termination factor, N-terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; Rho termination factor, RNA-binding domain; TIGRFAM: transcription termination factor Rho YP_004462297.1 COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005273: IPR005122; KEGG: tex:Teth514_1777 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Phage SPO1 DNA polymerase-related protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4 YP_004462298.1 COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726: IPR003171; KEGG: csc:Csac_1165 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase YP_004462299.1 COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: cth:Cthe_1919 MgtC/SapB transporter; PFAM: MgtC/SapB transporter; SPTR: MgtC/SapB transporter; PFAM: MgtC family YP_004462300.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141: IPR010140: IPR004013; KEGG: cth:Cthe_0724 HisJ family histidinol phosphate phosphatase; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Histidinol phosphate phosphatase HisJ family; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family YP_004462301.1 COGs: COG1362 Aspartyl aminopeptidase; InterPro IPR001948; KEGG: tpd:Teth39_0781 aminopeptidase 1; PFAM: peptidase M18 aminopeptidase I; SPTR: M18 family aminopeptidase; PFAM: Aminopeptidase I zinc metalloprotease (M18) YP_004462302.1 COGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR004517: IPR006195: IPR002314: IPR004516; KEGG: cth:Cthe_2880 ATP phosphoribosyltransferase regulatory subunit; PFAM: tRNA synthetase class II (G H P and S); PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase 2; TIGRFAM: histidyl-tRNA synthetase 2; PFAM: tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: ATP phosphoribosyltransferase, regulatory subunit YP_004462303.1 COGs: COG0040 ATP phosphoribosyltransferase; InterPro IPR013820: IPR018198; KEGG: cth:Cthe_2881 ATP phosphoribosyltransferase catalytic subunit; PFAM: ATP phosphoribosyltransferase catalytic region; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase YP_004462304.1 COGs: COG0141 Histidinol dehydrogenase; InterPro IPR012131: IPR001692; KEGG: cno:NT01CX_1062 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase YP_004462305.1 COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807: IPR020565; KEGG: tte:TTE2136 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase YP_004462306.1 COGs: COG0118 Glutamine amidotransferase; InterPro IPR010139: IPR017926: IPR000991: IPR016226; KEGG: cth:Cthe_2886 imidazole glycerol phosphate synthase subunit HisH; PFAM: glutamine amidotransferase class-I; SPTR: Imidazole glycerol phosphate synthase subunit hisH; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_004462307.1 COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006063: IPR006062; KEGG: cth:Cthe_2887 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_004462308.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; InterPro IPR004651: IPR006062: IPR018313; KEGG: cth:Cthe_2888 imidazole glycerol phosphate synthase subunit HisF; PFAM: histidine biosynthesis protein; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004462309.1 COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179: IPR002496: IPR021130; KEGG: tit:Thit_1813 phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase YP_004462310.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063: IPR012089; KEGG: ate:Athe_2599 PP-loop domain protein; PFAM: PP-loop domain protein; SPTR: PP-loop domain protein; PFAM: PP-loop family YP_004462311.1 InterPro IPR018649; KEGG: fpl:Ferp_1371 protein of unknown function DUF2078, membrane; PFAM: Protein of unknown function DUF2078, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2078) YP_004462312.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_0796 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1937 YP_004462313.1 COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR005746: IPR017936: IPR013766: IPR017937: IPR 006662; KEGG: syp:SYNPCC7002_A1614 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004462314.1 KEGG: cpi:Cpin_1852 protein of unknown function DUF21; SPTR: ECF-type sigma factor YP_004462315.1 KEGG: pto:PTO0364 C4-dicarboxylate transporter; SPTR: C4-dicarboxylate transporter YP_004462316.1 COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR010084: IPR013114; KEGG: pth:PTH_2770 (3R)-hydroxymyristoyl-ACP dehydratase; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; TIGRFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ YP_004462317.1 KEGG: tpd:Teth39_1792 hypothetical protein; SPTR: uncharacterized protein YP_004462318.1 COGs: COG2378 transcriptional regulator protein; KEGG: dal:Dalk_4932 helix-turn-helix type 11 domain protein; SPTR: uncharacterized protein YP_004462319.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: gym:GYMC10_0154 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide repeat YP_004462320.1 COGs: COG0752 Glycyl-tRNA synthetase alpha subunit; InterPro IPR002310: IPR006194; KEGG: pth:PTH_0899 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit YP_004462321.1 COGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR015944: IPR006194: IPR002311: IPR000209; KEGG: dau:Daud_0485 glycine--tRNA ligase; PFAM: glycyl-tRNA synthetase beta subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit; PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; glycyl-tRNA synthetase, tetrameric type, beta subunit YP_004462322.1 COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR010121: IPR002192: IPR008279: IPR000121: IPR 018274; KEGG: ate:Athe_1409 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase YP_004462323.1 KEGG: cpf:CPF_2645 glycogen debranching enzyme, type; SPTR: glycogen debranching enzyme, archaeal type YP_004462324.1 COGs: COG4219 Antirepressor regulating drug resistance predicted signal transduction N-terminal membrane component; InterPro IPR008756; KEGG: cac:CA_C3437 Zn-dependent protease; PFAM: peptidase M56 BlaR1; SPTR: Predicted membrane-associated Zn-dependent protease, HtpX family (BlaR subfamily); PFAM: BlaR1 peptidase M56 YP_004462325.1 COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: bca:BCE_1175 penicillinase repressor; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family; PFAM: TnsA endonuclease C terminal; Penicillinase repressor YP_004462326.1 KEGG: dat:HRM2_08340 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2500) YP_004462327.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: gsu:GSU2670 LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family YP_004462328.1 KEGG: pfh:PFHG_02044 conserved hypothetical protein; SPTR: TPR Domain containing protein YP_004462329.1 KEGG: jde:Jden_1946 ABC-2 type transporter; SPTR: uncharacterized protein YP_004462330.1 KEGG: dba:Dbac_3060 hypothetical protein; SPTR: uncharacterized protein YP_004462331.1 KEGG: glo:Glov_3346 polysulphide reductase NrfD; SPTR: Polysulphide reductase NrfD YP_004462332.1 KEGG: pis:Pisl_1633 NADH dehydrogenase subunit H; SPTR: AEC family malonate efflux carrier YP_004462333.1 KEGG: tcr:510593.49 kinetoplast DNA-associated protein; SPTR: uncharacterized protein YP_004462334.1 KEGG: ana:all4040 hypothetical protein; SPTR: KWG Leptospira; PFAM: KWG Leptospira YP_004462335.1 KEGG: lbc:LACBIDRAFT_303446 hypothetical protein; SPTR: uncharacterized protein YP_004462336.1 KEGG: mmu:100045458 similar to gamma-aminobutyric acid A receptor, epsilon; SPTR: Hypothetical lipoprotein YP_004462337.1 KEGG: rhi:NGR_a02490 probable ABC transporter permease y4mJ; SPTR: PROBABLE SUGAR UPTAKE ABC TRANSPORTER, PERMEase YP_004462338.1 KEGG: ttr:Tter_0129 phosphate transporter; SPTR: uncharacterized protein YP_004462339.1 COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607: IPR006261: IPR006674; KEGG: cth:Cthe_0897 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase YP_004462340.1 COGs: COG0358 DNA primase; InterPro IPR002694: IPR006154: IPR006295: IPR013264: IPR 006171: IPR019475; KEGG: clj:CLJU_c08210 DNA primase; PFAM: DNA primase catalytic core domain; TOPRIM domain-containing protein; DNA primase, DnaB-helicase binding domain; SMART: Toprim sub domain-containing protein; SPTR: DNA primase; TIGRFAM: DNA primase; PFAM: Toprim domain; DnaB-like helicase N terminal domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; DnaB-helicase binding domain of primase; TIGRFAM: DNA primase, catalytic core YP_004462341.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterPro IPR014284: IPR012760: IPR007127: IPR009042: IPR 007627: IPR007624: IPR007630: IPR000943; KEGG: tmt:Tmath_1554 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 1.1 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase, sigma 70 subunit, RpoD subfamily; TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain YP_004462342.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678: IPR017221; KEGG: tmt:Tmath_1552 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family YP_004462343.1 COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: cbb:CLD_1612 hypothetical protein; PFAM: protein of unknown function DUF164; SPTR: uncharacterized protein; PFAM: zinc ribbon domain YP_004462344.1 KEGG: amt:Amet_0078 hypothetical protein; SPTR: uncharacterized protein YP_004462345.1 COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040: IPR002821; KEGG: dhd:Dhaf_1734 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region YP_004462346.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593: IPR003439: IPR017940: IPR001140: IPR 017871; KEGG: tpd:Teth39_1499 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter transmembrane region YP_004462347.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR017871: IPR001140: IPR003439: IPR017940: IPR 003593; KEGG: tit:Thit_0781 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004462348.1 COGs: COG3858 glycosyl hydrolase; InterPro IPR018392: IPR002482; KEGG: aoe:Clos_1944 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; PFAM: LysM domain YP_004462349.1 KEGG: cno:NT01CX_1363 hypothetical protein; SPTR: uncharacterized protein YP_004462350.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: cpo:COPRO5265_0473 phosphoesterase; PFAM: metallophosphoesterase; SPTR: Phosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004462351.1 KEGG: ctt:CtCNB1_2434 hypothetical protein; SPTR: uncharacterized protein YP_004462352.1 COGs: COG2445 conserved hypothetical protein; InterPro IPR008201; KEGG: pmo:Pmob_1311 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF86 YP_004462353.1 KEGG: tte:TTE0452 hypothetical protein; SPTR: uncharacterized protein YP_004462354.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095: IPR014362: IPR006097: IPR006096; KEGG: dae:Dtox_3997 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: Glu/Leu/Phe/Val dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004462355.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: ate:Athe_0206 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis sensory transducer; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004462356.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR013477: IPR000891; KEGG: tmt:Tmath_0527 homocitrate synthase; PFAM: pyruvate carboxyltransferase; SPTR: Homocitrate synthase; TIGRFAM: homocitrate synthase; PFAM: HMGL-like; TIGRFAM: homocitrate synthase NifV YP_004462357.1 COGs: COG1048 Aconitase A; InterPro IPR018136: IPR001030: IPR006250: IPR011827: IPR 000573; KEGG: cth:Cthe_3158 aconitate hydratase; PFAM: aconitate hydratase domain-containing protein; SPTR: Aconitase; TIGRFAM: aconitate hydratase; 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase C-terminal domain; Aconitase (aconitate hydratase); TIGRFAM: aconitate hydratase, , Aquifex type; 3-isopropylmalate dehydratase, small subunit YP_004462358.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR019818: IPR001804; KEGG: ate:Athe_0525 isocitrate dehydrogenase (NAD(+)); PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NAD(+)); SPTR: Isocitrate dehydrogenase (NAD(+)); PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NAD-dependent, mitochondrial type; isopropylmalate/isohomocitrate dehydrogenases; isocitrate dehydrogenase, NADP-dependent, prokaryotic type YP_004462359.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: amt:Amet_0277 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein CapD; PFAM: Polysaccharide biosynthesis protein YP_004462360.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: ate:Athe_1244 cell envelope-related transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004462361.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: cce:Ccel_1005 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004462362.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR008354: IPR000683: IPR004104; KEGG: pjd:Pjdr2_0341 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase, NAD-binding Rossmann fold protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004462363.1 COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: dth:DICTH_0776 polyketide cyclase; PFAM: cyclase; PRIAM: Arylformamidase; SPTR: uncharacterized protein; PFAM: cyclase YP_004462364.1 COGs: COG1768 phosphohydrolase; InterPro IPR014578: IPR004843; KEGG: cce:Ccel_0808 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004462365.1 COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR020082: IPR000043: IPR015878; KEGG: cth:Cthe_1200 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase YP_004462366.1 COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: tit:Thit_1438 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase YP_004462367.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR010964: IPR002933: IPR011650; KEGG: hor:Hore_08190 Xaa-His dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Xaa-His dipeptidase; TIGRFAM: dipeptidase; PFAM: Peptidase M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase YP_004462368.1 KEGG: sce:YMR179W Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p; involved in telomere maintenance; SPTR: Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p; involved in telomere maintenance YP_004462369.1 KEGG: tpd:Teth39_0102 hypothetical protein; SPTR: uncharacterized protein YP_004462370.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR005750: IPR001986; KEGG: tte:TTE2684 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004462371.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: cce:Ccel_3102 rod shape-determining protein Mbl; PFAM: cell shape determining protein MreB/Mrl; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004462372.1 InterPro IPR014208; KEGG: tmt:Tmath_0198 sporulation transcriptional regulator SpoIIID; SPTR: Transcription regulator of sigma-E/sigma-K-dependent gene spoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID YP_004462373.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: amt:Amet_0360 peptidase M23B; PFAM: Peptidase M23; SPTR: Peptidase M23B; PFAM: Peptidase M23 YP_004462374.1 COGs: COG4786 Flagellar basal body rod protein; InterPro IPR019776: IPR020013: IPR001444: IPR010930; KEGG: tte:TTE0172 flagellar basal body and hook proteins; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: Flagellar basal body and hook proteins; TIGRFAM: fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins YP_004462375.1 COGs: COG4786 Flagellar basal body rod protein; InterPro IPR019776: IPR020013: IPR001444: IPR010930; KEGG: tit:Thit_0144 flagellar basal-body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar basal-body rod protein FlgG; TIGRFAM: fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins YP_004462376.1 COGs: COG4717 conserved hypothetical protein; KEGG: cce:Ccel_0032 hypothetical protein; SPTR: uncharacterized protein YP_004462377.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: hor:Hore_11160 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1 YP_004462378.1 COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: cpf:CPF_2416 Ser/Thr protein phosphatase; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004462379.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR003660: IPR003661: IPR003594: IPR 005467; KEGG: dae:Dtox_3084 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004462380.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: dhd:Dhaf_3739 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004462381.1 KEGG: mta:Moth_1828 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2680) YP_004462382.1 InterPro IPR014905; KEGG: ncr:NCU07975 hypothetical protein; PFAM: HIRAN; SPTR: uncharacterized protein; PFAM: HIRAN domain YP_004462383.1 KEGG: ani:AN7180.2 hypothetical protein; SPTR: Cutinase 3 YP_004462384.1 COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095: IPR001959; KEGG: mfs:MFS40622_1028 transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; transposase IS891/IS1136/IS1341 family; SPTR: Transposase, IS605 OrfB family, central region; TIGRFAM: transposase, IS605 OrfB family; PFAM: Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region YP_004462386.1 COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: tte:TTE0267 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: Threonine aldolase; PFAM: Beta-eliminating lyase YP_004462387.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR001411: IPR004638: IPR011701; KEGG: tmt:Tmath_0772 drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_004462388.1 COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: amt:Amet_0029 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel YP_004462389.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tte:TTE0651 cell wall biogenesis regulatory protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004462390.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: ate:Athe_1238 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004462391.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: tte:TTE0653 dehydrogenase and related proteins; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Predicted dehydrogenases and related proteins; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004462392.1 COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); InterPro IPR018357: IPR001451; KEGG: ckr:CKR_2805 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial transferase hexapeptide (three repeats) YP_004462393.1 KEGG: ate:Athe_1242 hypothetical protein; SPTR: uncharacterized protein; PFAM: O-Antigen ligase YP_004462394.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: ckr:CKR_2814 hypothetical protein; PFAM: glycosyl transferase group 1; SPTR: uncharacterized protein; manually curated; PFAM: Glycosyl transferases group 1 YP_004462395.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dtu:Dtur_0584 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1 YP_004462396.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: cbk:CLL_A3182 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004462397.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: csc:Csac_1092 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1; PFAM: Glycosyl transferases group 1 YP_004462398.1 COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); InterPro IPR020019: IPR001451; KEGG: bpf:BpOF4_06570 acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; SPTR: Acetyltransferase; TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family YP_004462399.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tte:TTE0667 cell wall biogenesis regulatory protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: Glutamine--scyllo-inositol transaminase; SPTR: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004462400.1 COGs: COG0253 Diaminopimelate epimerase; InterPro IPR018510: IPR001653; KEGG: csc:Csac_1315 diaminopimelate epimerase; PFAM: diaminopimelate epimerase; PRIAM: Diaminopimelate epimerase; SPTR: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; PFAM: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase YP_004462401.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: csc:Csac_0772 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; PFAM: Aminotransferase class I and II YP_004462402.1 COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310: IPR008286; KEGG: tte:TTE0093 arginine/lysine/ornithine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; SPTR: Arginine/lysine/ornithine decarboxylases; manually curated; PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain YP_004462403.1 COGs: COG0125 Thymidylate kinase; InterPro IPR018095: IPR018094: IPR000062; KEGG: aoe:Clos_0060 dTMP kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_004462404.1 InterPro IPR007016; KEGG: spn:SP_1893 hypothetical protein; PFAM: O-antigen polymerase; SPTR: uncharacterized protein; PFAM: O-Antigen ligase YP_004462405.1 COGs: COG3870 conserved hypothetical protein; InterPro IPR010375; KEGG: tpd:Teth39_2149 hypothetical protein; PFAM: protein of unknown function DUF970; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF970) YP_004462406.1 COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: tpd:Teth39_2148 hypothetical protein; PFAM: protein of unknown function DUF327; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF327) YP_004462407.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: aoe:Clos_0062 DNA polymerase III, delta prime subunit; SPTR: DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: ATPase associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau YP_004462408.1 COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: aoe:Clos_0063 PSP1 domain-containing protein; PFAM: PSP1 domain protein; SPTR: PSP1 domain protein; PFAM: PSP1 C-terminal conserved region YP_004462409.1 InterPro IPR017900: IPR017896; KEGG: slp:Slip_0675 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain YP_004462410.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328: IPR013154: IPR013149; KEGG: hor:Hore_13100 L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase YP_004462411.1 COGs: COG2385 Sporulation protein and related protein; InterPro IPR013486: IPR013693: IPR013247: IPR003646; KEGG: bld:BLi03809 hypothetical protein; PFAM: Stage II sporulation protein D; SH3 type 3 domain protein; SMART: SH3 domain protein; SPTR: uncharacterized protein; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; Bacterial SH3 domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; SpoIID/LytB domain YP_004462412.1 COGs: COG2344 AT-rich DNA-binding protein; InterPro IPR009718: IPR003781; KEGG: tpd:Teth39_1737 redox-sensing transcriptional repressor REX; PFAM: CoA-binding domain protein; Rex DNA-binding domain protein; SPTR: CoA-binding domain protein; PFAM: CoA binding domain; DNA-binding protein N-terminus YP_004462413.1 InterPro IPR007903; KEGG: tjr:TherJR_2358 PRC-barrel domain protein; PFAM: PRC-barrel domain protein; SPTR: PRC-barrel domain protein; PFAM: PRC-barrel domain YP_004462414.1 COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391: IPR011098; KEGG: tte:TTE1768 hypothetical protein; PFAM: VanW family protein; G5 domain protein; SPTR: uncharacterized protein; PFAM: peptidoglycan binding domain; VanW like protein; G5 domain YP_004462415.1 COGs: COG1522 Transcriptional regulators; InterPro IPR019887: IPR019888; KEGG: csc:Csac_1961 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Transcriptional regulator, AsnC family; PFAM: AsnC family YP_004462416.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR001176: IPR004839; KEGG: mta:Moth_1188 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; PFAM: Aminotransferase class I and II YP_004462417.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: cpo:COPRO5265_1598 oxidoreductase, 2-nitropropane dioxygenase; PFAM: 2-nitropropane dioxygenase NPD; SPTR: Oxidoreductase, 2-nitropropane dioxygenase; PFAM: 2-nitropropane dioxygenase YP_004462418.1 COGs: COG2407 L-fucose isomerase and related protein; InterPro IPR012888: IPR012889: IPR015888; KEGG: tna:CTN_0381 L-fucose isomerase; PFAM: L-fucose isomerase _2 domain protein; L-fucose isomerase _1 domain protein; L-fucose isomerase-like-like; SPTR: L-fucose isomerase; PFAM: L-fucose isomerase, C-terminal domain; L-fucose isomerase, first N-terminal domain; L-fucose isomerase, second N-terminal domain YP_004462420.1 KEGG: cpo:COPRO5265_0475 hypothetical protein; SPTR: Conserved Archaeal protein YP_004462421.1 KEGG: rpf:Rpic12D_1512 hypothetical protein; SPTR: uncharacterized protein YP_004462422.1 COGs: COG2607 ATPase (AAA+ superfamily); InterPro IPR008533: IPR003593; KEGG: dae:Dtox_2937 protein of unknown function DUF815; PFAM: protein of unknown function DUF815; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF815) YP_004462423.1 KEGG: amt:Amet_1438 hypothetical protein; SPTR: uncharacterized protein YP_004462424.1 COGs: COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); InterPro IPR001469: IPR020546: IPR020547; KEGG: tmt:Tmath_0698 ATP synthase F1, epsilon subunit; PFAM: ATPase, F1 complex, delta/epsilon subunit-like; SPTR: ATP synthase F1, epsilon subunit; TIGRFAM: ATP synthase F1, epsilon subunit; PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain; ATP synthase, Delta/Epsilon chain, long alpha-helix domain; TIGRFAM: ATP synthase, F1 epsilon subunit (delta in mitochondria) YP_004462425.1 COGs: COG0055 F0F1-type ATP synthase beta subunit; InterPro IPR005722: IPR004100: IPR000194: IPR000793: IPR 003593; KEGG: csc:Csac_1970 F0F1 ATP synthase subunit beta; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: ATP synthase subunit beta; TIGRFAM: ATP synthase F1, beta subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATP synthase, F1 beta subunit YP_004462426.1 COGs: COG0224 F0F1-type ATP synthase gamma subunit; InterPro IPR000131; KEGG: tmt:Tmath_0696 ATP synthase F1, gamma subunit; PFAM: H+transporting two-sector ATPase gamma subunit; SPTR: ATP synthase gamma chain; TIGRFAM: ATP synthase F1, gamma subunit; PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 gamma subunit YP_004462427.1 COGs: COG0056 F0F1-type ATP synthase alpha subunit; InterPro IPR020003: IPR005294: IPR004100: IPR000194: IPR 000793; KEGG: ate:Athe_1426 ATP synthase F1, alpha subunit; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SPTR: ATP synthase subunit alpha; TIGRFAM: ATP synthase F1, alpha subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: proton translocating ATP synthase, F1 alpha subunit YP_004462428.1 COGs: COG0712 F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); InterPro IPR000711; KEGG: tmt:Tmath_0694 ATP synthase F1, delta subunit; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; SPTR: ATP synthase F1, delta subunit; TIGRFAM: ATP synthase F1, delta subunit; PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 delta subunit YP_004462429.1 COGs: COG0711 F0F1-type ATP synthase subunit b; InterPro IPR005864: IPR002146: IPR006888; KEGG: cth:Cthe_2604 ATP synthase F0, B subunit; PFAM: H+transporting two-sector ATPase B/B' subunit; Cor1/Xlr/Xmr family; SPTR: ATP synthase subunit b; TIGRFAM: ATP synthase F0, B subunit; PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_004462430.1 InterPro IPR020537: IPR000454: IPR005953: IPR002379; KEGG: tmt:Tmath_0692 ATP synthase F0, C subunit; PFAM: H+transporting two-sector ATPase C subunit; SPTR: ATP synthase subunit c; TIGRFAM: ATP synthase F0, C subunit; PFAM: ATP synthase subunit C; TIGRFAM: ATP synthase, F0 subunit c YP_004462431.1 COGs: COG0356 F0F1-type ATP synthase subunit a; InterPro IPR000568; KEGG: tte:TTE0630 F0F1 ATP synthase subunit A; PFAM: H+transporting two-sector ATPase A subunit; SPTR: ATP synthase subunit a; TIGRFAM: ATP synthase F0, A subunit; PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_004462432.1 KEGG: mse:Msed_1501 sodium/hydrogen exchanger; SPTR: uncharacterized protein YP_004462433.1 InterPro IPR001584; KEGG: tjr:TherJR_2621 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004462434.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: csc:Csac_0762 glycosidase, PH1107-related; PFAM: glycosidase related protein; SPTR: Glycosidase, PH1107-related; PFAM: Domain of unknown function (DUF377) YP_004462435.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR006073: IPR004396: IPR002917: IPR013029; KEGG: cth:Cthe_0877 GTP-dependent nucleic acid-binding protein EngD; PFAM: protein of unknown function DUF933; GTP-binding protein HSR1-related; SPTR: GTP-binding protein YchF; TIGRFAM: GTP-binding protein YchF; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF YP_004462436.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR007527: IPR000330: IPR001650: IPR014021: IPR 014001; KEGG: tjr:TherJR_0590 SNF2-related protein; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Non-specific serine/threonine protein kinase; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain; SWIM zinc finger YP_004462437.1 InterPro IPR018126: IPR001448; KEGG: tte:TTE0795 small acid-soluble spore protein; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type YP_004462438.1 KEGG: tte:TTE0794 hypothetical protein; SPTR: uncharacterized protein YP_004462439.1 COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: chy:CHY_1268 glycerate kinase 2; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase; TIGRFAM: glycerate kinase YP_004462440.1 KEGG: vpo:Kpol_480p15 hypothetical protein; SPTR: uncharacterized protein YP_004462441.1 COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658: IPR014237: IPR002645; KEGG: bpf:BpOF4_14825 anti-sigma F factor antagonist (stage II sporulation protein AA); PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-sigma F factor antagonist; anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist YP_004462442.1 COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR010194: IPR003594; KEGG: cth:Cthe_0119 anti-sigma F factor; PFAM: ATP-binding region ATPase domain protein; PRIAM: Non-specific serine/threonine protein kinase; SMART: ATP-binding region ATPase domain protein; SPTR: anti-sigma regulatory factor, serine/threonine protein kinase; TIGRFAM: anti-sigma F factor; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: anti-sigma F factor YP_004462443.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterPro IPR000943: IPR014236: IPR014322: IPR014284: IPR 007627: IPR007624: IPR007630; KEGG: ctc:CTC02246 sporulation sigma factor SigF; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-F factor; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-F factor; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily YP_004462444.1 COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: tte:TTE2480 major membrane immunogen precursor; PFAM: FMN-binding domain protein; SPTR: Major membrane immunogen; PFAM: FMN-binding domain YP_004462445.1 COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR005856: IPR005859: IPR001926; KEGG: mta:Moth_1706 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases YP_004462446.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR007110; KEGG: tpt:Tpet_0494 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004462447.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149; KEGG: ate:Athe_2083 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004462448.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: tex:Teth514_0985 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family YP_004462449.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112; KEGG: ate:Athe_2084 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: domain; FAD binding domain YP_004462450.1 COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein YP_004462451.1 COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: blt:Balat_1503 nucleoside hydrolase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; SPTR: uncharacterized protein; PFAM: Inosine-uridine preferring nucleoside hydrolase YP_004462452.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: scl:sce3333 aldo/keto reductase oxidoreductase; PFAM: aldo/keto reductase; SPTR: Oxidoreductase, aldo/keto reductase; PFAM: Aldo/keto reductase YP_004462453.1 KEGG: pth:PTH_1310 hypothetical protein; SPTR: uncharacterized protein YP_004462454.1 InterPro IPR019300; KEGG: dae:Dtox_3961 hypothetical protein; PFAM: RNA-binding protein, predicted; SPTR: uncharacterized protein; PFAM: Predicted RNA-binding protein YP_004462455.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR004792: IPR001327; KEGG: tte:TTE2697 uncharacterized FAD-dependent dehydrogenase; PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD dependent oxidoreductase; manually curated; PFAM: HI0933-like protein; Glucose inhibited division protein A YP_004462456.1 COGs: COG0104 Adenylosuccinate synthase; InterPro IPR018220: IPR001114; KEGG: tte:TTE2696 adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; PRIAM: Adenylosuccinate synthase; SMART: adenylosuccinate synthetase; SPTR: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthetase; PFAM: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase YP_004462457.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR003594: IPR005467; KEGG: sfu:Sfum_2495 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Two-component sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462458.1 COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: amt:Amet_4762 peptidase M1, membrane alanine aminopeptidase-like protein; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: Peptidase M1, membrane alanine aminopeptidase-like protein; PFAM: Peptidase M1 YP_004462459.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392: IPR011098: IPR016047: IPR002482; KEGG: aoe:Clos_2792 peptidase M23B; PFAM: Peptidase M23; G5 domain protein; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidase M23B; PFAM: Peptidase M23; G5 domain; LysM domain YP_004462460.1 COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR001497: IPR014048: IPR008332; KEGG: aoe:Clos_0936 methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; methylguanine DNA methyltransferase ribonuclease domain protein; SPTR: Methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004462461.1 KEGG: ate:Athe_1766 hypothetical protein; SPTR: uncharacterized protein YP_004462462.1 InterPro IPR014199; KEGG: cth:Cthe_2071 hypothetical protein; PFAM: Sporulation protein YtxC; SPTR: uncharacterized protein; PFAM: YtxC-like family; TIGRFAM: sporulation protein YtxC YP_004462463.1 COGs: COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding); InterPro IPR006699; KEGG: tte:TTE2004 glycerol-3-phosphate responsive antiterminator (mRNA-binding); PFAM: glycerol-3-phosphate responsive antiterminator; SPTR: Glycerol-3-phosphate responsive antiterminator (MRNA-binding); PFAM: Glycerol-3-phosphate responsive antiterminator YP_004462464.1 COGs: COG0579 dehydrogenase; InterPro IPR006076: IPR007419; KEGG: cno:NT01CX_0612 glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: Glycerol-3-phosphate dehydrogenase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase YP_004462465.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR001412: IPR013027: IPR000103; KEGG: ctc:CTC02435 sarcosine oxidase alpha subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Sarcosine oxidase alpha subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004462466.1 COGs: COG3862 Uncharacterized protein with conserved CXXC pairs; InterPro IPR012460; KEGG: cno:NT01CX_0610 hypothetical protein; PFAM: protein of unknown function DUF1667; SPTR: Conserved protein; PFAM: Protein of unknown function (DUF1667) YP_004462467.1 COGs: COG1683 conserved hypothetical protein; InterPro IPR007553; KEGG: cno:NT01CX_1774 hypothetical protein; PFAM: protein of unknown function DUF523; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF523) YP_004462468.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: pjd:Pjdr2_4258 efflux transporter, RND family, MFP subunit; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004462469.1 InterPro IPR003838; KEGG: pjd:Pjdr2_5946 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004462470.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR014249: IPR002797; KEGG: tmt:Tmath_0641 stage V sporulation protein B; PFAM: polysaccharide biosynthesis protein; SPTR: Stage V sporulation protein B; TIGRFAM: stage V sporulation protein B; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B YP_004462471.1 COGs: COG0502 Biotin synthase; InterPro IPR005244: IPR007197: IPR006638; KEGG: csc:Csac_0491 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase; PFAM: Radical SAM superfamily YP_004462472.1 COGs: COG2813 16S RNA G1207 methylase RsmC; InterPro IPR007848; KEGG: cth:Cthe_2935 methyltransferase small; PFAM: methyltransferase small; SPTR: Methyltransferase small; PFAM: Methyltransferase small domain YP_004462473.1 COGs: COG4463 Transcriptional repressor of class III stress genes; InterPro IPR008463; KEGG: cno:NT01CX_1084 transcription regulator CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; SPTR: Transcription regulator ctsR; PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR) YP_004462474.1 COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: tte:TTE2329 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: UvrB/UvrC protein; PFAM: UvrB/uvrC motif YP_004462475.1 COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: aac:Aaci_2741 ATP:guanido phosphotransferase; PFAM: ATP:guanido phosphotransferase; SPTR: ATP:guanido phosphotransferase; PFAM: ATP:guanido phosphotransferase, C-terminal catalytic domain YP_004462476.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR018368: IPR001270: IPR004176: IPR003959: IPR 001943: IPR013093: IPR019489: IPR003593; KEGG: tte:TTE2327 ATPase with chaperone activity, ATP-binding subunit; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPases with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); UvrB/uvrC motif YP_004462477.1 COGs: COG1066 ATP-dependent serine protease; InterPro IPR004504: IPR007694: IPR003593; KEGG: cth:Cthe_1786 DNA repair protein RadA; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; PFAM: KaiC; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: DNA repair protein RadA YP_004462478.1 KEGG: cth:Cthe_1784 hypothetical protein; SPTR: uncharacterized protein YP_004462479.1 COGs: COG3267 Type II secretory pathway component ExeA (predicted ATPase); KEGG: tpd:Teth39_2206 AAA ATPase; SPTR: AAA ATPase; PFAM: Uncharacterized conserved protein (DUF2075) YP_004462480.1 COGs: COG3344 Retron-type reverse transcriptase; InterPro IPR000123: IPR000477: IPR013597; KEGG: ere:EUBREC_2457 recombinase; PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; SPTR: uncharacterized protein; PFAM: Reverse transcriptase (RNA-dependent DNA polymerase); Group II intron, maturase-specific domain YP_004462481.1 KEGG: shl:Shal_1353 signal transduction protein; SPTR: signal transduction protein YP_004462482.1 COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterPro IPR003439: IPR017940: IPR003593; KEGG: ate:Athe_1962 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter transmembrane region YP_004462483.1 InterPro IPR001387; KEGG: lrh:LGG_00142 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix YP_004462484.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: pmo:Pmob_1895 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase YP_004462485.1 COGs: COG0171 NAD synthase; InterPro IPR003694: IPR014445: IPR003010; KEGG: tmt:Tmath_0700 NAD+ synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: NAD+ synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase YP_004462486.1 COGs: COG1453 oxidoreductase of the aldo/keto reductase; InterPro IPR017900: IPR001395: IPR017896; KEGG: tit:Thit_2206 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase YP_004462487.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: pjd:Pjdr2_4207 L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; SPTR: L-ribulose-5-phosphate 4-epimerase; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004462488.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: csc:Csac_0297 ABC-type sugar transport system periplasmic component-like protein; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462489.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR010559: IPR003594; KEGG: ate:Athe_0852 sensor with HAMP domain; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: sensor with HAMP domain; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462490.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018062: IPR020449: IPR001789: IPR000005: IPR 018060; KEGG: eat:EAT1b_2335 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004462491.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_3305 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462492.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_4251 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type sugar transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462493.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_1230 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462494.1 InterPro IPR001258: IPR013026: IPR013017; KEGG: dtu:Dtur_1591 NHL repeat containing protein; PFAM: NHL repeat containing protein; SPTR: NHL repeat containing protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; Yip1 domain YP_004462495.1 KEGG: gym:GYMC10_1233 hypothetical protein; SPTR: uncharacterized protein YP_004462496.1 COGs: COG1484 DNA replication protein; InterPro IPR002611: IPR003593; KEGG: slp:Slip_1606 IstB domain protein ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004462497.1 COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR013249: IPR001584; KEGG: slp:Slip_1605 integrase catalytic region; PFAM: Sigma-70 region 4 type 2; SPTR: Integrase catalytic region; PFAM: Sigma-70, region 4; Integrase core domain YP_004462498.1 KEGG: pjd:Pjdr2_4247 hypothetical protein; SPTR: uncharacterized protein YP_004462499.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_4246 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004462500.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_1235 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462501.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cth:Cthe_1046 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462502.1 COGs: COG2730 Endoglucanase; InterPro IPR018087: IPR001547; KEGG: dth:DICTH_0008 endoglucanase H; PFAM: glycoside hydrolase 5; SPTR: Endoglucanase H; PFAM: Cellulase (glycosyl hydrolase 5) YP_004462503.1 COGs: COG3693 Beta-1 4-xylanase; InterPro IPR001000; KEGG: tmt:Tmath_0247 endo-1,4-beta-xylanase; PFAM: glycoside hydrolase 10; PRIAM: Endo-1,4-beta-xylanase; SMART: glycoside hydrolase 10; SPTR: Beta-1,4-xylanase; PFAM: Glycosyl hydrolase 10 YP_004462504.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR017871: IPR003439: IPR017940: IPR003593; KEGG: cpf:CPF_0830 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004462505.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018062: IPR020449: IPR000005: IPR018060; KEGG: gym:GYMC10_3281 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain YP_004462506.1 KEGG: caa:Caka_0351 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004462507.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904: IPR002347: IPR002198; KEGG: sth:STH2303 gluconate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; PFAM: short chain dehydrogenase YP_004462508.1 COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: cce:Ccel_1263 GntR domain protein; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR domain protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004462509.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149; KEGG: bcm:Bcenmc03_5781 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004462510.1 COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: adg:Adeg_0469 transketolase domain protein; PFAM: Transketolase domain-containing protein; SPTR: Transketolase; PFAM: Transketolase, thiamine diphosphate binding domain YP_004462511.1 COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475: IPR005476; KEGG: drm:Dred_3074 transketolase, central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase domain-containing protein; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_004462512.1 COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR002204: IPR006183: IPR006398: IPR006115; KEGG: set:SEN3088 tartronate semialdehyde reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; SPTR: 2-hydroxy-3-oxopropionate reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; 2-hydroxy-3-oxopropionate reductase YP_004462513.1 COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: aoe:Clos_2543 gluconate transporter; PFAM: Gluconate transporter; SPTR: Gluconate transporter; TIGRFAM: gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter YP_004462514.1 COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: amt:Amet_0501 gluconate transporter; PFAM: Gluconate transporter; SPTR: Gluconate transporter; PFAM: GntP family permease YP_004462515.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018062: IPR000005: IPR018060: IPR000160; KEGG: cce:Ccel_0142 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004462516.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2438 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462517.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_3248 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462518.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_1656 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004462519.1 COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845: IPR003018: IPR000873; KEGG: chy:CHY_0572 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; GAF domain protein; SMART: GAF domain protein; SPTR: Acetyl-coenzyme A synthetase; PFAM: GAF domain; AMP-binding enzyme YP_004462520.1 COGs: COG1067 ATP-dependent protease; InterPro IPR001984; KEGG: tex:Teth514_1297 peptidase S16, lon domain-containing protein; SPTR: Peptidase S16, lon domain protein; PFAM: Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related ATP-dependent protease YP_004462521.1 COGs: COG0450 Peroxiredoxin; InterPro IPR000866: IPR019479: IPR017936; KEGG: ate:Athe_0023 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; PRIAM: Peroxiredoxin; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family YP_004462522.1 KEGG: cce:Ccel_1464 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004462523.1 COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR018177: IPR001557: IPR011304: IPR001236; KEGG: csc:Csac_1027 L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: Malate dehydrogenase (NAD); TIGRFAM: L-lactate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: L-lactate dehydrogenase YP_004462524.1 KEGG: dae:Dtox_2708 hypothetical protein; SPTR: uncharacterized protein YP_004462525.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: mta:Moth_2498 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004462526.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439: IPR003593; KEGG: hmo:HM1_0493 branched chain amino acid abc transporter, PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Branched chain amino acid abc transporter, ; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004462527.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: hmo:HM1_0492 branched-chain amino acid abc transporter, permease; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004462528.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: drm:Dred_2239 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004462529.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR000709: IPR001828; KEGG: gyc:GYMC61_3057 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004462530.1 KEGG: cbt:CLH_1355 autoinducer prepeptide; SPTR: lipoprotein YP_004462531.1 COGs: COG4512 Membrane protein ly involved in post-translational modification of the autoinducing quorum-sensing peptide; InterPro IPR006741; KEGG: tjr:TherJR_2656 accessory gene regulator B; PFAM: Accessory gene regulator B; SMART: Accessory gene regulator B; SPTR: Accessory gene regulator protein B; PFAM: Accessory gene regulator B YP_004462532.1 KEGG: amt:Amet_1280 hypothetical protein; SPTR: uncharacterized protein YP_004462533.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: tye:THEYE_A1260 deoxyribonuclease, TatD family; PFAM: Radical SAM domain protein; SPTR: Deoxyribonuclease, TatD family; PFAM: Radical SAM superfamily YP_004462534.1 COGs: COG2426 membrane protein; InterPro IPR009577; KEGG: amt:Amet_0715 small multi-drug export; PFAM: small multi-drug export protein; SPTR: small multi-drug export; PFAM: small multi-drug export protein YP_004462535.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mmp:MMP0644 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation efflux protein; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004462536.1 COGs: COG3857 ATP-dependent nuclease subunit B; KEGG: afn:Acfer_1333 ATP-dependent nuclease subunit B-like protein; SPTR: ATP-dependent nuclease subunit B-like protein YP_004462537.1 COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR000212: IPR014016: IPR014017; KEGG: bts:Btus_2147 exodeoxyribonuclease V; PFAM: UvrD/REP helicase; SPTR: UvrD/REP helicase; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_004462538.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: cbe:Cbei_4671 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004462539.1 KEGG: bpf:BpOF4_22014 hypothetical protein; SPTR: uncharacterized protein YP_004462540.1 InterPro IPR019734: IPR013026; KEGG: bpf:BpOF4_22019 hypothetical protein; SPTR: uncharacterized protein YP_004462541.1 KEGG: pfd:PFDG_03662 hypothetical protein; SPTR: uncharacterized protein YP_004462542.1 InterPro IPR001818; KEGG: ere:EUBREC_1345 hypothetical protein; PFAM: peptidase M10A and M12B matrixin and adamalysin; SPTR: uncharacterized protein YP_004462543.1 KEGG: ere:EUBREC_1346 hypothetical protein; SPTR: uncharacterized protein YP_004462544.1 KEGG: dvi:Dvir_GJ12022 GJ12022 gene product from transcript GJ12022-RA; SPTR: uncharacterized protein YP_004462545.1 KEGG: tit:Thit_0800 hypothetical protein; SPTR: uncharacterized protein YP_004462546.1 KEGG: fnu:FN1649 oligopeptide transport ATP-binding protein OppD; SPTR: Peptidase A5, thermopsin YP_004462547.1 KEGG: gym:GYMC10_0238 hypothetical protein; SPTR: uncharacterized protein YP_004462548.1 COGs: COG0693 intracellular protease/amidase; InterPro IPR006286: IPR002818; KEGG: oih:OB0506 intracellular proteinase; PFAM: ThiJ/PfpI domain-containing protein; SPTR: Protein YhbO; TIGRFAM: intracellular protease, PfpI family; PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family YP_004462549.1 COGs: COG0143 Methionyl-tRNA synthetase; InterPro IPR001412: IPR014758: IPR002304: IPR015413; KEGG: tit:Thit_0098 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); SPTR: Methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); TIGRFAM: methionyl-tRNA synthetase YP_004462550.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR018228: IPR015991: IPR012278: IPR001130; KEGG: cdf:CD3539 deoxyribonuclease; PFAM: TatD-related deoxyribonuclease; SPTR: uncharacterized protein; TIGRFAM: hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_004462551.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: dsa:Desal_1351 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004462552.1 COGs: COG1550 conserved hypothetical protein; InterPro IPR007546; KEGG: hau:Haur_3704 hypothetical protein; PFAM: protein of unknown function DUF503; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF503) YP_004462553.1 COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: cth:Cthe_2687 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: Thioesterase superfamily; PFAM: Thioesterase superfamily YP_004462554.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999: IPR005256: IPR006805: IPR015890; KEGG: cth:Cthe_0875 anthranilate synthase, component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase, component I; TIGRFAM: anthranilate synthase component I; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: anthranilate synthase component I, non-proteobacterial lineages YP_004462555.1 COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR005940: IPR017459: IPR000312; KEGG: cth:Cthe_0873 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase 3; Glycosyl transferase, family 3-like; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase, a/b domain; Glycosyl transferase, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_004462556.1 COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR001468: IPR013798; KEGG: cth:Cthe_0872 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase YP_004462557.1 COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: ckr:CKR_1174 hypothetical protein; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase YP_004462558.1 COGs: COG0133 Tryptophan synthase beta chain; InterPro IPR006653: IPR006654: IPR001926; KEGG: tte:TTE1578 tryptophan synthase subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Tryptophan synthase, beta subunit; TIGRFAM: tryptophan synthase, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit YP_004462559.1 COGs: COG0159 Tryptophan synthase alpha chain; InterPro IPR018204: IPR002028; KEGG: tte:TTE1577 tryptophan synthase subunit alpha; PFAM: tryptophan synthase alpha chain; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit YP_004462560.1 KEGG: bha:BH2916 hypothetical protein; SPTR: BH2916 protein YP_004462561.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: pjd:Pjdr2_4259 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004462562.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: bbe:BBR47_15650 hypothetical protein; PFAM: secretion protein HlyD family protein; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004462563.1 InterPro IPR003838; KEGG: pjd:Pjdr2_4257 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004462564.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: pjd:Pjdr2_4256 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004462565.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: tpd:Teth39_2246 phage integrase; PFAM: integrase; SPTR: Phage integrase; PFAM: Phage integrase YP_004462566.1 COGs: COG2856 Zn peptidase; InterPro IPR010359; KEGG: cbi:CLJ_B2579 hypothetical immunity region protein 2; PFAM: protein of unknown function DUF955; SPTR: Hypothetical immunity region protein 2; PFAM: Domain of unknown function (DUF955) YP_004462567.1 InterPro IPR001387; KEGG: cbk:CLL_A1952 transcriptional regulator, MerR family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Immunity repressor protein; PFAM: Helix-turn-helix YP_004462568.1 InterPro IPR001387; KEGG: ddf:DEFDS_1061 transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: MATE efflux family protein; PFAM: Helix-turn-helix YP_004462569.1 InterPro IPR002711: IPR001387: IPR003615; KEGG: pfu:PF0900 hypothetical protein; PFAM: helix-turn-helix domain protein; HNH endonuclease; SMART: HNH nuclease; helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix; HNH endonuclease YP_004462570.1 InterPro IPR010093; KEGG: cth:Cthe_2463 DNA binding domain-containing protein; SPTR: DNA binding domain, excisionase; TIGRFAM: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004462571.1 KEGG: dre:100334565 fasciculation and elongation protein zeta-1-like YP_004462572.1 KEGG: sga:GALLO_1934 hypothetical protein; SPTR: uncharacterized protein YP_004462573.1 KEGG: bbt:BBta_4667 DNA topoisomerase IV subunit A YP_004462574.1 KEGG: tan:TA02800 GTPase; SPTR: GTPase YP_004462575.1 KEGG: bhy:BHWA1_02340 hypothetical protein YP_004462576.1 KEGG: cth:Cthe_2464 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacteriophage Mu Gam like protein YP_004462577.1 KEGG: ckr:CKR_2913 hypothetical protein; SPTR: uncharacterized protein YP_004462579.1 KEGG: tai:Taci_0572 amidohydrolase; SPTR: Amidohydrolase YP_004462580.1 InterPro IPR006343; KEGG: bge:BC1002_6533 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: primosome, DnaD subunit; PFAM: Replication initiation and membrane attachment protein (DnaB); TIGRFAM: DnaD and phage-associated domain YP_004462581.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR000169: IPR007693: IPR007694; KEGG: tte:TTE2774 replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SPTR: Replicative DNA helicase; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase YP_004462582.1 KEGG: tet:TTHERM_00047130 DNA-directed RNA polymerase, omega subunit family protein; SPTR: DNA-directed RNA polymerase, omega subunit family protein YP_004462584.1 InterPro IPR008822; KEGG: lpl:lp_2433 prophage Lp2 protein 24; PFAM: endodeoxyribonuclease RusA; SPTR: uncharacterized protein; PFAM: Endodeoxyribonuclease RusA YP_004462585.1 KEGG: ptr:750513 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) YP_004462586.1 KEGG: tml:GSTUM_00011925001 hypothetical protein; SPTR: ABC transporter, substrate binding protein (Glycine betaine) YP_004462587.1 KEGG: clu:CLUG_04779 hypothetical protein; SPTR: uncharacterized protein YP_004462588.1 KEGG: afr:AFE_2415 hypothetical protein; SPTR: uncharacterized protein YP_004462589.1 KEGG: cth:Cthe_2469 RinA family phage transcriptional regulator; SPTR: Phage transcriptional regulator, RinA family; PFAM: Protein of unknown function (DUF1492); TIGRFAM: phage transcriptional activator, RinA family YP_004462591.1 COGs: COG3728 Phage terminase small subunit; InterPro IPR005335; KEGG: cce:Ccel_3051 terminase small subunit; PFAM: Terminase small subunit; SPTR: Terminase small subunit; PFAM: Terminase small subunit YP_004462592.1 KEGG: cbe:Cbei_1636 hypothetical protein; SPTR: uncharacterized protein YP_004462593.1 KEGG: dae:Dtox_4229 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage portal protein, SPP1 Gp6-like YP_004462594.1 KEGG: cbe:Cbei_1638 hypothetical protein; SPTR: uncharacterized protein YP_004462595.1 KEGG: mfs:MFS40622_0645 DNA polymerase II, large subunit DP2; SPTR: uncharacterized protein YP_004462596.1 KEGG: tit:Thit_1389 hypothetical protein; SPTR: uncharacterized protein YP_004462597.1 KEGG: dae:Dtox_4233 hypothetical protein; SPTR: uncharacterized protein YP_004462598.1 KEGG: dae:Dtox_4234 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2190) YP_004462599.1 KEGG: dae:Dtox_4235 hypothetical protein; SPTR: uncharacterized protein YP_004462600.1 KEGG: tit:Thit_1386 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004462601.1 KEGG: dae:Dtox_4236 hypothetical protein; SPTR: uncharacterized protein YP_004462602.1 KEGG: dae:Dtox_4237 hypothetical protein; SPTR: uncharacterized protein YP_004462603.1 KEGG: tit:Thit_1383 hypothetical protein; SPTR: uncharacterized protein YP_004462604.1 KEGG: dae:Dtox_4239 hypothetical protein; SPTR: uncharacterized protein YP_004462605.1 KEGG: dae:Dtox_4240 hypothetical protein; SPTR: uncharacterized protein YP_004462606.1 InterPro IPR020287; KEGG: dae:Dtox_4241 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage tail sheath protein YP_004462607.1 InterPro IPR018989; KEGG: gym:GYMC10_5400 XkdM protein, phage-like element PBSX; PFAM: XkdM protein, phage-like element PBSX; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2001) YP_004462608.1 InterPro IPR014986; KEGG: cbo:CBO2340 hypothetical protein; PFAM: XkdN-like protein; SPTR: Hypothetical phage protein; PFAM: Phage XkdN-like protein YP_004462609.1 KEGG: ere:EUBREC_2096 hypothetical protein; SPTR: uncharacterized protein YP_004462610.1 COGs: COG3941 Mu-like prophage protein; InterPro IPR013491; KEGG: ckr:CKR_1711 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: phage tape measure protein; TIGRFAM: tape measure domain YP_004462611.1 KEGG: ere:EUBREC_1597 hypothetical protein; SPTR: uncharacterized protein YP_004462612.1 COGs: COG1652 Uncharacterized protein containing LysM domain; InterPro IPR018392: IPR002482; KEGG: dae:Dtox_4246 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; PFAM: LysM domain YP_004462613.1 KEGG: dae:Dtox_4247 hypothetical protein; SPTR: uncharacterized protein YP_004462614.1 KEGG: cbo:CBO2335 hypothetical protein; SPTR: Hypothetical phage protein YP_004462615.1 InterPro IPR020288; KEGG: dae:Dtox_4249 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2634) YP_004462616.1 COGs: COG3299 Uncharacterized homolog of phage Mu protein gp47; InterPro IPR006949; KEGG: gym:GYMC10_5392 baseplate J family protein; PFAM: Baseplate J family protein; SPTR: Baseplate J family protein; PFAM: Baseplate J-like protein YP_004462617.1 KEGG: gym:GYMC10_5391 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2313) YP_004462618.1 KEGG: gka:GK0543 hypothetical protein; SPTR: Phage-related protein YP_004462619.1 KEGG: vpo:Kpol_416p4 hypothetical protein; SPTR: uncharacterized protein GF2gp17 YP_004462620.1 KEGG: afv:AFLA_129760 RNA binding protein Jsn1, SPTR: RNA-binding protein YP_004462621.1 InterPro IPR010022; KEGG: ppe:PEPE_0804 hypothetical protein; PFAM: uncharacterised protein XkdX; SPTR: uncharacterized protein; TIGRFAM: phage uncharacterized protein, XkdX family; PFAM: Phage uncharacterised protein (Phage_XkdX); TIGRFAM: phage uncharacterized protein, XkdX family YP_004462622.1 KEGG: cth:Cthe_2497 hypothetical protein; SPTR: uncharacterized protein YP_004462623.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: cdl:CDR20291_1818 phage-related cell wall hydrolase (endolysin); PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: uncharacterized protein; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004462625.1 KEGG: bha:BH3511 hypothetical protein; SPTR: BH3511 protein YP_004462626.1 KEGG: pai:PAE3630 hypothetical protein; SPTR: uncharacterized protein YP_004462627.1 KEGG: fre:Franean1_4252 WD-40 repeat-containing protein; SPTR: WD-40 repeat protein YP_004462628.1 KEGG: tgr:Tgr7_1432 stationary phase survival protein SurE; SPTR: Integral membrane protein YP_004462629.1 KEGG: emi:Emin_1039 hypothetical protein; SPTR: Predicted protein YP_004462630.1 KEGG: tet:TTHERM_01054340 Regulator of chromosome condensation (RCC1); SPTR: Regulator of chromosome condensation (RCC1) YP_004462631.1 InterPro IPR001584; KEGG: pth:PTH_2713 hypothetical protein; PFAM: Integrase catalytic region; SPTR: uncharacterized protein; PFAM: Integrase core domain YP_004462632.1 COGs: COG0018 Arginyl-tRNA synthetase; InterPro IPR001412: IPR015945: IPR001278: IPR005148: IPR 008909; KEGG: amt:Amet_1714 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase YP_004462634.1 COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR018158: IPR002320: IPR004095: IPR012947: IPR 002314: IPR004154: IPR006195; KEGG: cth:Cthe_1228 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; TGS domain-containing protein; Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TGS domain; TIGRFAM: threonyl-tRNA synthetase YP_004462635.1 COGs: COG0290 Translation initiation factor 3 (IF-3); InterPro IPR019813: IPR001288: IPR019814: IPR019815; KEGG: ate:Athe_1204 translation initiation factor IF-3; PFAM: Translation initiation factor 3-like; SPTR: Translation initiation factor IF-3; TIGRFAM: translation initiation factor IF-3; PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_004462636.1 COGs: COG0291 Ribosomal protein L35; InterPro IPR018265: IPR001706: IPR021137; KEGG: cbe:Cbei_1570 50S ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_004462637.1 COGs: COG0292 Ribosomal protein L20; InterPro IPR005813; KEGG: tte:TTE1691 50S ribosomal protein L20; PFAM: ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: ribosomal protein L20; PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_004462638.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR014221: IPR010822: IPR001932; KEGG: cth:Cthe_2681 serine phosphatase; PFAM: Stage II sporulation protein E; PRIAM: Phosphoprotein phosphatase; SMART: protein phosphatase 2C domain protein; SPTR: Serine phosphatase; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation protein E (SpoIIE); TIGRFAM: stage II sporulation protein E YP_004462639.1 InterPro IPR002035; KEGG: aoe:Clos_0429 hypothetical protein; PFAM: von Willebrand factor type A; SPTR: uncharacterized protein; PFAM: von Willebrand factor type A domain YP_004462640.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017441: IPR017442: IPR000719: IPR002290; KEGG: amt:Amet_4545 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; SPTR: Protein kinase; PFAM: Protein kinase domain YP_004462641.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR012795: IPR012796: IPR011063: IPR015262; KEGG: tte:TTE2395 ATPase; PFAM: PP-loop domain protein; Protein of unkown function DUF1946 PP-loop ATpase; SPTR: tRNA(Ile)-lysidine synthetase; TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: TilS substrate C-terminal domain; PP-loop family; TilS substrate binding domain; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain YP_004462642.1 COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904: IPR000836; KEGG: drm:Dred_2376 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_004462643.1 COGs: COG0465 ATP-dependent Zn protease; InterPro IPR003960: IPR005936: IPR003959: IPR000642: IPR 003593; KEGG: tpd:Teth39_0301 ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: FtsH Extracellular; Peptidase M41; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004462644.1 COGs: COG5496 thioesterase; KEGG: amt:Amet_0908 thioesterase; SPTR: Thioesterase; PFAM: Thioesterase superfamily YP_004462645.1 KEGG: tpd:Teth39_0304 hypothetical protein; SPTR: uncharacterized protein YP_004462646.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR018334: IPR001845; KEGG: cbb:CLD_0268 cadmium resistance transcriptional regulator CadC; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: cadmium resistance transcriptional regulator CadC; PFAM: Bacterial regulatory protein, arsR family YP_004462647.1 COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: cpe:CPE1612 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: Membrane protein, DedA family; PFAM: SNARE associated Golgi protein YP_004462648.1 COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: cbf:CLI_2674 DedA family protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004462649.1 KEGG: cth:Cthe_2261 hypothetical protein; SPTR: uncharacterized protein YP_004462650.1 COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490: IPR016160; KEGG: tmt:Tmath_2248 V-type ATPase 116 kDa subunit; PFAM: V-type ATPase 116 kDa subunit; SPTR: H(+)-transporting two-sector ATPase; PFAM: V-type ATPase 116kDa subunit family YP_004462651.1 InterPro IPR000245: IPR002379; KEGG: cdl:CDR20291_2793 V-type ATP synthase subunit K; PFAM: H+transporting two-sector ATPase C subunit; SPTR: ATP synthase subunit C; PFAM: ATP synthase subunit C YP_004462652.1 COGs: COG1390 H+-ATPase subunit E; InterPro IPR002842; KEGG: cbf:CLI_2693 V-type ATPase, E subunit; PFAM: H+transporting two-sector ATPase E subunit; SPTR: V-type ATPase, E subunit; PFAM: ATP synthase (E/31 kDa) subunit YP_004462653.1 COGs: COG1527 H+-ATPase subunit C; InterPro IPR002843; KEGG: ctc:CTC00997 V-type ATP synthase subunit C; PFAM: H+transporting two-sector ATPase C (AC39) subunit; SPTR: H(+)-transporting two-sector ATPase; PFAM: ATP synthase (C/AC39) subunit YP_004462654.1 COGs: COG1436 H+-ATPase subunit F; InterPro IPR008218; KEGG: tmt:Tmath_2244 vacuolar H+transporting two-sector ATPase F subunit; PFAM: Vacuolar H+transporting two-sector ATPase F subunit; SPTR: Vacuolar H+transporting two-sector ATPase F subunit; PFAM: ATP synthase (F/14-kDa) subunit YP_004462655.1 COGs: COG1155 H+-ATPase subunit A; InterPro IPR006141: IPR004042: IPR003587: IPR003586: IPR 006142: IPR004100: IPR000194: IPR000793: IPR020003; KEGG: pfu:PF0182 V-type ATP synthase subunit A; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: Hedgehog/intein hint domain protein; SPTR: V-type ATP synthase alpha chain; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta chain, C terminal domain; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region YP_004462656.1 COGs: COG1156 H+-ATPase subunit B; InterPro IPR004100: IPR000194: IPR000793: IPR020003; KEGG: cth:Cthe_2268 V-type ATP synthase subunit B; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SPTR: H(+)-transporting two-sector ATPase; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATP synthase archaeal, B subunit YP_004462657.1 COGs: COG1394 H+-ATPase subunit D; InterPro IPR002699; KEGG: ctc:CTC01001 V-type ATP synthase subunit D; PFAM: H+transporting two-sector ATPase D subunit; SPTR: NtpD; TIGRFAM: V-type ATPase, D subunit; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D YP_004462658.1 COGs: COG4354 bile acid beta-glucosidase; InterPro IPR018303; KEGG: ttr:Tter_2468 protein of unknown function DUF608; SPTR: uncharacterized protein; PFAM: beta-Glucocerebrosidase 2 N terminal; Protein of unknown function, DUF608 YP_004462659.1 COGs: COG3537 alpha-1 2-mannosidase; InterPro IPR005887: IPR012939; KEGG: phe:Phep_3359 alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; SPTR: Alpha-1,2-mannosidase; TIGRFAM: alpha-1,2-mannosidase; manually curated; PFAM: Glycosyl hydrolase 92; TIGRFAM: alpha-1,2-mannosidase YP_004462660.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: cpo:COPRO5265_1393 phosphoesterase; PFAM: metallophosphoesterase; SPTR: Phosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004462661.1 KEGG: gau:GAU_0076 ABC transporter ATP-binding protein; SPTR: ABC transporter, ATP-binding protein YP_004462662.1 InterPro IPR003838; KEGG: dhd:Dhaf_3804 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004462663.1 InterPro IPR003838; KEGG: dhd:Dhaf_3803 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004462664.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: afl:Aflv_2827 ABC-type antimicrobial peptide transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004462665.1 KEGG: taf:THA_347 peptidase; SPTR: Bystin family protein YP_004462666.1 COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011896: IPR011766; KEGG: tte:TTE0960 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Pyruvate ferredoxin oxidoreductase beta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family YP_004462667.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752: IPR002880; KEGG: tte:TTE0961 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit YP_004462668.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772; KEGG: ttr:Tter_0181 glycoside hydrolase 3 domain protein; PFAM: glycoside hydrolase 3 domain protein; SPTR: Glycoside hydrolase 3 domain protein; PFAM: Glycosyl hydrolase 3 C terminal domain; Glycosyl hydrolase 3 N terminal domain YP_004462669.1 COGs: COG0616 Periplasmic serine protease (ClpP class); KEGG: ddf:DEFDS_0218 hypothetical protein; SPTR: uncharacterized protein; PFAM: Serine dehydrogenasease YP_004462670.1 COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: tpd:Teth39_1878 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; PFAM: Rhomboid family YP_004462671.1 COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; InterPro IPR001046; KEGG: ate:Athe_0657 natural resistance-associated macrophage protein; PFAM: natural resistance-associated macrophage protein; SPTR: Natural resistance-associated macrophage protein; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters YP_004462672.1 COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR000644: IPR007903: IPR006668; KEGG: csc:Csac_1222 MgtE intracellular region; PFAM: MgtE intracellular region; PRC-barrel domain protein; CBS domain containing protein; SPTR: MgtE intracellular region; PFAM: MgtE intracellular N domain; CBS domain; PRC-barrel domain YP_004462673.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: aac:Aaci_2618 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004462674.1 InterPro IPR020480: IPR011701; KEGG: tte:TTE2499 major facilitator superfamily permease; PFAM: major facilitator superfamily MFS_1; SPTR: Permeases of the major facilitator superfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: oligosaccharide:H+ symporter YP_004462675.1 KEGG: tte:TTE0116 S-layer-like domain-containing protein; SPTR: uncharacterized protein YP_004462676.1 COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: tit:Thit_1600 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase YP_004462677.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR005467: IPR003594: IPR004358: IPR016381: IPR 008595: IPR011712; KEGG: cth:Cthe_1268 histidine kinase; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Sensor protein DegS; Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462678.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: cth:Cthe_1267 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004462679.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: ssp:SSP0142 permease; PFAM: Auxin Efflux Carrier; SPTR: permease; PFAM: Membrane transport protein YP_004462680.1 COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439: IPR003593: IPR013611: IPR017871; KEGG: csc:Csac_2346 ABC transporter related; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; TOBE domain YP_004462681.1 COGs: COG3835 Sugar diacid utilization regulator; KEGG: cce:Ccel_2908 transcriptional regulator, CdaR; SPTR: uncharacterized protein YP_004462682.1 COGs: COG2884 ATPase involved in cell division; InterPro IPR003439: IPR003593: IPR005286: IPR017871; KEGG: tte:TTE1977 cell division ATPase; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Predicted ATPase involved in cell division; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE YP_004462683.1 COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: tpd:Teth39_0564 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004462684.1 COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: tpd:Teth39_0565 peptidase M23B; PFAM: Peptidase M23; SPTR: Peptidase M23B; PFAM: Peptidase M23 YP_004462685.1 COGs: COG1418 HD superfamily hydrolase; InterPro IPR004088: IPR004087: IPR003607: IPR017705: IPR 006675: IPR018111: IPR006674; KEGG: mta:Moth_1081 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; K Homology, type 1, subgroup; SMART: metal-dependent phosphohydrolase HD region; KH domain protein; SPTR: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; TIGRFAM: YmdA/YtgF protein; metal dependent phophohydrolase; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG YP_004462686.1 COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR003141: IPR004013; KEGG: pth:PTH_1307 metal-dependent phosphoesterases; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: PHP domain protein; PFAM: PHP domain YP_004462687.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839: IPR004838; KEGG: cth:Cthe_0755 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: L-aspartate aminotransferase; PFAM: Aminotransferase class I and II YP_004462688.1 COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362: IPR004769: IPR019468: IPR020557: IPR 013838; KEGG: cth:Cthe_0741 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase YP_004462689.1 COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192: IPR020578; KEGG: cce:Ccel_1188 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V YP_004462690.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236: IPR006139: IPR006140: IPR002912; KEGG: tpd:Teth39_0145 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase YP_004462691.1 KEGG: aac:Aaci_1980 hypothetical protein; SPTR: uncharacterized protein YP_004462692.1 COGs: COG1381 Recombinational DNA repair protein (RecF pathway); InterPro IPR003717; KEGG: aoe:Clos_1253 DNA repair protein RecO; PFAM: Recombination protein O RecO; SPTR: DNA repair protein recO; TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O C terminal; Recombination protein O N terminal; TIGRFAM: DNA repair protein RecO YP_004462693.1 COGs: COG1109 Phosphomannomutase; InterPro IPR005841: IPR006352: IPR005844: IPR005845: IPR 005846: IPR005843: IPR016066; KEGG: cno:NT01CX_1165 phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphoglucosamine mutase; TIGRFAM: phosphoglucosamine mutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase YP_004462694.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR017932: IPR005855: IPR000583: IPR001347; KEGG: tte:TTE2190 glucosamine--fructose-6-phosphate aminotransferase; PFAM: sugar isomerase (SIS); glutamine amidotransferase class-II; SPTR: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; TIGRFAM: glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: SIS domain; Glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing) YP_004462695.1 COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: ckr:CKR_1968 hypothetical protein; PFAM: Penicillinase repressor; SPTR: uncharacterized protein; PFAM: Penicillinase repressor YP_004462696.1 COGs: COG4219 Antirepressor regulating drug resistance predicted signal transduction N-terminal membrane component; InterPro IPR008756; KEGG: ckr:CKR_1967 hypothetical protein; PFAM: peptidase M56 BlaR1; SPTR: Peptidase M56 BlaR1; PFAM: BlaR1 peptidase M56 YP_004462697.1 KEGG: hmo:HM1_2322 polynucleotide phosphorylase/polyadenylase; SPTR: Possible exported protein YP_004462698.1 COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR001584: IPR013249; KEGG: slp:Slip_1605 integrase catalytic region; PFAM: Sigma-70 region 4 type 2; SPTR: Integrase catalytic region; PFAM: Sigma-70, region 4; Integrase core domain YP_004462699.1 COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: slp:Slip_1606 IstB domain protein ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004462700.1 COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; KEGG: cte:CT1622 DNA helicase, SPTR: uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF559) YP_004462701.1 COGs: COG1923 Uncharacterized host factor I protein; InterPro IPR005001: IPR001163; KEGG: cth:Cthe_0774 RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein core; SPTR: RNA chaperone Hfq; TIGRFAM: RNA chaperone Hfq; PFAM: LSM domain; TIGRFAM: RNA chaperone Hfq YP_004462702.1 COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; InterPro IPR000684; KEGG: cth:Cthe_3155 beta-lactamase-like protein; SPTR: Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily YP_004462703.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797: IPR004477: IPR004365; KEGG: cth:Cthe_0606 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; nucleic acid binding OB-fold tRNA/helicase-type; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2 YP_004462704.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790: IPR010372; KEGG: tjr:TherJR_2462 DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; SPTR: DNA-directed DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_004462705.1 COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: chy:CHY_0540 hypothetical protein; PFAM: protein of unknown function DUF965; SPTR: UPF0297 protein CHY_0540; PFAM: Bacterial protein of unknown function (DUF965) YP_004462706.1 COGs: COG0816 endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); InterPro IPR006641: IPR005227; KEGG: aoe:Clos_1663 Holliday junction resolvase YqgF; PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; SPTR: Holliday junction resolvase; PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: RNAse H-fold protein YqgF YP_004462707.1 InterPro IPR009711; KEGG: cce:Ccel_2238 protein of unknown function DUF1292; PFAM: protein of unknown function DUF1292; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1292) YP_004462708.1 COGs: COG0370 Fe2+ transport system protein B; InterPro IPR006073: IPR005225: IPR002917; KEGG: gme:Gmet_2444 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; SPTR: Ferrous iron transport protein B; TIGRFAM: small GTP-binding protein; PFAM: Ferrous iron transport protein B; TIGRFAM: small GTP-binding protein domain YP_004462709.1 COGs: COG0370 Fe2+ transport system protein B; InterPro IPR011619: IPR011642: IPR011640; KEGG: ppd:Ppro_3681 ferrous iron transport protein B; PFAM: Ferrous iron transport B domain-containing protein; nucleoside recognition domain protein; Ferrous iron transport protein B domain-containing protein; SPTR: Ferrous iron transport protein B; PFAM: Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB YP_004462710.1 KEGG: gbm:Gbem_1589 hypothetical protein; SPTR: uncharacterized protein YP_004462711.1 InterPro IPR007167; KEGG: ppd:Ppro_0775 DtxR family iron dependent repressor; PFAM: FeoA family protein; SPTR: Iron (Metal) dependent repressor, DtxR family; PFAM: FeoA domain YP_004462712.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: tmt:Tmath_1100 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family YP_004462713.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR002744: IPR019591: IPR000808; KEGG: tte:TTE0119 chromosome partitioning ATPase; PFAM: ATPase-like, ParA/MinD; protein of unknown function DUF59; SPTR: ATPases involved in chromosome partitioning; PFAM: ParA/MinD ATPase like; Domain of unknown function DUF59; ATPase MipZ YP_004462714.1 KEGG: bvu:BVU_0175 acetyl xylan esterase; SPTR: uncharacterized protein YP_004462715.1 KEGG: lmh:LMHCC_0014 cell wall surface anchor family protein; SPTR: Cell wall surface anchor family protein YP_004462716.1 KEGG: ckr:CKR_0259 hypothetical protein; SPTR: uncharacterized protein YP_004462717.1 KEGG: cin:100179337 similar to Polycystic kidney disease 1-like 3 precursor (Polycystin-1L3) (PC1-like 3 protein); SPTR: uncharacterized protein YP_004462718.1 InterPro IPR001584; KEGG: tjr:TherJR_2621 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004462719.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020060: IPR004527: IPR020058: IPR001412; KEGG: mta:Moth_1132 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: Glutamyl-tRNA synthetase; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004462720.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439: IPR003593: IPR017871; KEGG: cth:Cthe_2270 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004462721.1 KEGG: chy:CHY_2148 hypothetical protein; SPTR: Conserved domain protein YP_004462722.1 KEGG: afn:Acfer_1115 hypothetical protein; SPTR: uncharacterized protein YP_004462723.1 KEGG: ptm:GSPATT00012287001 hypothetical protein; SPTR: Chromosome undetermined scaffold_34, whole genome shotgun sequence. YP_004462724.1 KEGG: rca:Rcas_2768 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2961) YP_004462725.1 COGs: COG4492 ACT domain-containing protein; InterPro IPR008310: IPR002912; KEGG: ate:Athe_1958 hypothetical protein; PFAM: amino acid-binding ACT domain protein; SPTR: UPF0735 ACT domain-containing protein Csac_0995; PFAM: ACT domain YP_004462726.1 COGs: COG0460 Homoserine dehydrogenase; InterPro IPR016204: IPR005106: IPR001342: IPR019811; KEGG: ate:Athe_1959 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; SPTR: Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase YP_004462727.1 COGs: COG0498 Threonine synthase; InterPro IPR004450: IPR001926: IPR000634: IPR018184; KEGG: tmt:Tmath_2178 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_004462728.1 COGs: COG0083 Homoserine kinase; InterPro IPR000870: IPR006204: IPR013750: IPR006203; KEGG: pmo:Pmob_1581 homoserine kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: Homoserine kinase; TIGRFAM: homoserine kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: homoserine kinase YP_004462729.1 COGs: COG0527 Aspartokinase; InterPro IPR005260: IPR001341: IPR001048: IPR002912: IPR 018042; KEGG: csc:Csac_0991 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase YP_004462730.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: aoe:Clos_0856 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004462731.1 KEGG: amt:Amet_3667 hypothetical protein; SPTR: uncharacterized protein YP_004462732.1 COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004821: IPR005248: IPR004820; KEGG: tte:TTE0918 nicotinic acid mononucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Probable nicotinate-nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain YP_004462733.1 COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR003607: IPR005249: IPR006674; KEGG: tte:TTE0919 HD superfamily hydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: HD superfamily hydrolase of NAD metabolism; uncharacterized domain HDIG YP_004462734.1 COGs: COG0481 Membrane GTPase LepA; InterPro IPR000795: IPR005225: IPR006297: IPR004161: IPR 000640: IPR013842; KEGG: tpd:Teth39_1397 GTP-binding protein LepA; PFAM: GTP-binding protein LepA domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein; manually curated; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004462735.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638: IPR004559: IPR007197: IPR010723; KEGG: drm:Dred_2500 oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase YP_004462736.1 COGs: COG1420 Transcriptional regulator of heat shock gene; InterPro IPR002571: IPR021153; KEGG: csc:Csac_1750 heat-inducible transcription repressor HrcA; PFAM: Winged helix-turn-helix transcription repressor, HrcA-like; SPTR: Heat-inducible transcription repressor hrcA; TIGRFAM: heat-inducible transcription repressor HrcA; PFAM: HrcA protein C terminal domain; TIGRFAM: heat shock gene repressor HrcA YP_004462737.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: cth:Cthe_1323 GrpE protein; PFAM: GrpE protein; SPTR: Protein grpE; PFAM: GrpE YP_004462738.1 COGs: COG0443 Molecular chaperone; InterPro IPR001023: IPR012725: IPR013126: IPR018181; KEGG: tpd:Teth39_1393 molecular chaperone DnaK; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; TIGRFAM: chaperone protein DnaK; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_004462739.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR001305: IPR003095: IPR012724: IPR 002939: IPR018253; KEGG: tjr:TherJR_2449 chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Chaperone protein DnaJ; TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ C terminal region; DnaJ central domain (4 repeats); DnaJ domain; TIGRFAM: chaperone protein DnaJ YP_004462740.1 COGs: COG2264 Ribosomal protein L11 methylase; InterPro IPR004498: IPR010456; KEGG: aoe:Clos_1235 ribosomal protein L11 methyltransferase; PFAM: ribosomal L11 methyltransferase; SPTR: Ribosomal protein L11 methyltransferase; TIGRFAM: ribosomal protein L11 methyltransferase; PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase YP_004462741.1 COGs: COG0621 2-methylthioadenine synthetase; InterPro IPR002792: IPR013848: IPR006638: IPR005839: IPR 006467: IPR007197: IPR020612; KEGG: cth:Cthe_0150 RNA modification protein; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: RNA modification enzyme, MiaB family; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family YP_004462742.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310: IPR019808; KEGG: tpd:Teth39_1375 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; PFAM: HIT domain YP_004462743.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018060: IPR001789: IPR020449: IPR000005: IPR 018062: IPR016160; KEGG: cce:Ccel_2113 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004462744.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003594: IPR010559; KEGG: tex:Teth514_0398 histidine kinase internal region; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462745.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2438 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462746.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4741 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462747.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: bld:BLi03168 YtcQ; PFAM: extracellular solute-binding protein family 1; SPTR: multiple sugar transport system substrate-binding protein YtcQ; PFAM: Bacterial extracellular solute-binding protein YP_004462748.1 InterPro IPR003953; KEGG: cbe:Cbei_4529 pyridine nucleotide-disulphide oxidoreductase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD dependent oxidoreductase YP_004462749.1 KEGG: cbe:Cbei_4529 pyridine nucleotide-disulphide oxidoreductase; SPTR: Pyridine nucleotide-disulphide oxidoreductase YP_004462750.1 InterPro IPR003953; KEGG: psl:Psta_3017 hypothetical protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: uncharacterized protein; PFAM: FAD binding domain YP_004462751.1 KEGG: mst:Msp_0761 MtaA1; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004462752.1 KEGG: bbe:BBR47_51240 hypothetical protein; SPTR: uncharacterized protein YP_004462753.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307: IPR011418; KEGG: csc:Csac_0390 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; AP endonuclease 2 domain protein; SPTR: uncharacterized protein; PFAM: AP endonuclease 2 C terminus; Xylose isomerase-like TIM barrel YP_004462754.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: pjd:Pjdr2_1117 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004462755.1 COGs: COG0289 Dihydrodipicolinate reductase; InterPro IPR011770: IPR000846: IPR002912; KEGG: tex:Teth514_2185 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; amino acid-binding ACT domain protein; SPTR: Dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: ACT domain; Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase; aspartate kinase YP_004462756.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR005263: IPR020625; KEGG: tpd:Teth39_1502 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase; TIGRFAM: dihydrodipicolinate synthase YP_004462757.1 COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterPro IPR012080: IPR005986: IPR000534: IPR012280; KEGG: cth:Cthe_0961 aspartate semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase dimerisation region; Semialdehyde dehydrogenase NAD - binding; PRIAM: Aspartate-semialdehyde dehydrogenase; SPTR: Aspartate semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; manually curated; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) YP_004462758.1 KEGG: hhe:HH1684 hypothetical protein; SPTR: Transcriptional regulator, MarR family YP_004462759.1 KEGG: tjr:TherJR_2956 transposase IS4 family protein; SPTR: Transposase YP_004462760.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: gvi:gll2564 hypothetical protein; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase; PFAM: Aldose 1-epimerase YP_004462761.1 KEGG: tpd:Teth39_2102 hypothetical protein; SPTR: uncharacterized protein YP_004462762.1 KEGG: amt:Amet_0904 hypothetical protein; SPTR: uncharacterized protein YP_004462763.1 COGs: COG1164 Oligoendopeptidase F; InterPro IPR004438: IPR013647: IPR001567; KEGG: hmo:HM1_0557 oligoendopeptidase F; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F; SPTR: Oligoendopeptidase f; TIGRFAM: oligoendopeptidase F; PFAM: Oligopeptidase F; Peptidase M3; TIGRFAM: oligoendopeptidase F YP_004462764.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; InterPro IPR003824; KEGG: tmt:Tmath_1011 undecaprenol kinase; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenol kinase; TIGRFAM: undecaprenol kinase; PFAM: Bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP YP_004462765.1 COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; InterPro IPR005144: IPR003796; KEGG: cth:Cthe_0450 transcriptional regulator NrdR; PFAM: ATP-cone domain protein; SPTR: Transcriptional repressor nrdR; PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR YP_004462766.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: tte:TTE1633 response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004462767.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR003439: IPR015850: IPR003593: IPR005670: IPR 017871; KEGG: tte:TTE1628 ABC-type phosphate transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Phosphate import ATP-binding protein pstB 2; TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_004462768.1 COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170; KEGG: tpd:Teth39_0831 phosphate uptake regulator, PhoU; PFAM: PhoU family protein; SPTR: Phosphate uptake regulator, PhoU; TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU YP_004462769.1 COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: tte:TTE1021 carbonic anhydrase; PFAM: transferase hexapeptide repeat containing protein; SPTR: Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; PFAM: Bacterial transferase hexapeptide (three repeats) YP_004462770.1 COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: cce:Ccel_2205 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: AIR carboxylase YP_004462771.1 COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232: IPR011063; KEGG: ckr:CKR_2212 hypothetical protein; PFAM: PP-loop domain protein; SPTR: uncharacterized protein; PFAM: NAD synthase; TIGRFAM: conserved hypothetical protein TIGR00268 YP_004462772.1 COGs: COG1453 oxidoreductase of the aldo/keto reductase; InterPro IPR017896: IPR001395: IPR017900; KEGG: cth:Cthe_0236 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase YP_004462773.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: mif:Metin_0066 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family YP_004462774.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: tpd:Teth39_1904 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein YP_004462775.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR005865: IPR000522; KEGG: amt:Amet_3618 transport system permease; PFAM: transport system permease; SPTR: Transport system permease; PFAM: FecCD transport family YP_004462776.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439: IPR003593: IPR017871; KEGG: tte:TTE0374 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; PFAM: ABC transporter YP_004462777.1 COGs: COG1492 Cobyric acid synthase; InterPro IPR017929: IPR004459: IPR011698; KEGG: tmt:Tmath_0413 cobyric acid synthase CobQ; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: Cobyric acid synthase; TIGRFAM: cobyric acid synthase CobQ; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyric acid synthase CobQ YP_004462778.1 COGs: COG1270 Cobalamin biosynthesis protein CobD/CbiB; InterPro IPR004485; KEGG: cno:NT01CX_2082 cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; SPTR: Cobalamin biosynthesis protein CobD; TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD YP_004462779.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: amt:Amet_3614 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase YP_004462780.1 COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; InterPro IPR012363: IPR006204: IPR013750; KEGG: amt:Amet_0068 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: uncharacterized protein; PFAM: GHMP kinases N terminal domain YP_004462781.1 COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537: IPR005479; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_004462782.1 KEGG: tit:Thit_0102 hypothetical protein; SPTR: uncharacterized protein YP_004462783.1 COGs: COG0757 3-dehydroquinate dehydratase II; InterPro IPR001874: IPR018509; KEGG: bmq:BMQ_4474 3-dehydroquinate dehydratase II; PFAM: dehydroquinase class II; PRIAM: 3-dehydroquinate dehydratase; SPTR: 3-dehydroquinate dehydratase; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II YP_004462784.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001131; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: Xaa-Pro aminopeptidase; PFAM: Metallopeptidase M24; Creatinase/Prolidase N-terminal domain YP_004462785.1 COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); InterPro IPR020599: IPR011768: IPR013185: IPR001059: IPR 015365: IPR013852; KEGG: tmt:Tmath_1130 translation elongation factor P; PFAM: Elongation factor P; Elongation factor KOW-like domain-containing protein; Elongation factor P/YeiP protein; SPTR: Elongation factor P; TIGRFAM: translation elongation factor P; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P YP_004462786.1 KEGG: aoe:Clos_1623 hypothetical protein; SPTR: uncharacterized protein YP_004462787.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR001808: IPR000600; KEGG: bha:BH1094 transcriptional repressor of the xylose operon; PFAM: ROK family protein; SMART: regulatory protein Crp; SPTR: Transcriptional repressor of the xylose operon; PFAM: ROK family; MarR family YP_004462788.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: bfr:BF3068 methyltransferase CmuC; SPTR: Uroporphyrinogen-III decarboxylase; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004462789.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059: IPR006061; KEGG: kol:Kole_0479 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004462790.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ttr:Tter_2523 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462791.1 InterPro IPR000421; KEGG: phe:Phep_0759 hypothetical protein; PFAM: coagulation factor 5/8 type domain protein; SPTR: uncharacterized protein; PFAM: F5/8 type C domain YP_004462792.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ttr:Tter_2216 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004462793.1 KEGG: abi:Aboo_0136 hypothetical protein; SPTR: uncharacterized protein YP_004462794.1 COGs: COG3854 conserved hypothetical protein; InterPro IPR003593: IPR014217; KEGG: tpd:Teth39_1088 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase; TIGRFAM: stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA YP_004462795.1 InterPro IPR014198; KEGG: cth:Cthe_0844 stage III sporulation protein spoIIIAB; PFAM: Sporulation stage III protein AB; SPTR: Stage III sporulation protein spoIIIAB; TIGRFAM: stage III sporulation protein AB; PFAM: Stage III sporulation protein AB (spore_III_AB); TIGRFAM: stage III sporulation protein AB YP_004462796.1 InterPro IPR009570; KEGG: tmt:Tmath_1134 stage III sporulation protein AC; SPTR: Stage III sporulation protein AC; TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AC YP_004462797.1 InterPro IPR014211; KEGG: amt:Amet_2495 sporulation stage III, protein AD; SPTR: Sporulation stage III, protein AD; TIGRFAM: stage III sporulation protein AD; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AD YP_004462798.1 InterPro IPR014194; KEGG: amt:Amet_2496 sporulation stage III, protein AE; PFAM: Sporulation stage III protein AE; SPTR: Sporulation stage III, protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE YP_004462799.1 InterPro IPR014245; KEGG: cce:Ccel_1911 hypothetical protein; PFAM: Sporulation stage III protein AF; SPTR: uncharacterized protein; TIGRFAM: stage III sporulation protein AF; PFAM: Stage III sporulation protein AF (Spore_III_AF); TIGRFAM: stage III sporulation protein AF YP_004462800.1 InterPro IPR014195; KEGG: cby:CLM_2106 stage III sporulation protein AG; SPTR: Stage III sporulation protein AG; TIGRFAM: stage III sporulation protein AG; TIGRFAM: stage III sporulation protein AG YP_004462801.1 KEGG: amt:Amet_2499 hypothetical protein; SPTR: Stage III sporulation protein AH YP_004462802.1 COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: tpd:Teth39_1096 hypothetical protein; PFAM: protein of unknown function DUF322; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF322) YP_004462803.1 KEGG: bbe:BBR47_23330 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF322) YP_004462804.1 InterPro IPR018730; KEGG: csc:Csac_2124 hypothetical protein; PFAM: Protein of unknown function DUF2273; SPTR: uncharacterized protein; PFAM: Small integral membrane protein (DUF2273) YP_004462805.1 COGs: COG0781 Transcription termination factor; InterPro IPR011605: IPR006027; KEGG: cno:NT01CX_1978 transcription antitermination protein NusB; PFAM: NusB/RsmB/TIM44; SPTR: N utilization substance protein B homolog; TIGRFAM: transcription antitermination factor NusB; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_004462806.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR000672: IPR020630: IPR020631: IPR020867; KEGG: mta:Moth_1516 methenyltetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methylenetetrahydrofolate dehydrogenase (NADP(+)); SPTR: Bifunctional protein folD; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004462807.1 COGs: COG1570 Exonuclease VII large subunit; InterPro IPR003753: IPR004365: IPR020579; KEGG: cth:Cthe_0833 exodeoxyribonuclease VII large subunit; PFAM: Exonuclease VII, large subunit-like; nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Exodeoxyribonuclease 7 large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit YP_004462808.1 COGs: COG1722 Exonuclease VII small subunit; InterPro IPR003761; KEGG: cce:Ccel_1903 exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; SPTR: Exodeoxyribonuclease 7 small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit YP_004462809.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: tmt:Tmath_1145 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Geranyltranstransferase; PFAM: Polyprenyl synthetase YP_004462810.1 KEGG: ctc:CTC01576 membrane spanning protein; SPTR: Membrane spanning protein YP_004462811.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; InterPro IPR005477: IPR005475: IPR005476: IPR005474: IPR 020826; KEGG: slp:Slip_0434 deoxyxylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004462812.1 COGs: COG0061 sugar kinase; InterPro IPR002504: IPR018277; KEGG: tte:TTE1300 kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: NAD(+)/NADH kinase, ; PFAM: ATP-NAD kinase YP_004462813.1 COGs: COG1438 Arginine repressor; InterPro IPR001669: IPR020899; KEGG: tmt:Tmath_1150 arginine repressor, ArgR; PFAM: Arginine repressor-like; SPTR: Arginine repressor, ArgR; TIGRFAM: arginine repressor; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_004462814.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR004604: IPR003395; KEGG: amt:Amet_2511 DNA repair protein RecN; PFAM: SMC domain protein; SPTR: DNA repair protein RecN; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_004462815.1 InterPro IPR014219: IPR008763; KEGG: tmt:Tmath_1152 stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; PRIAM: SpoIVB peptidase; SPTR: Peptidase S55, SpoIVB; TIGRFAM: stage IV sporulation protein B; PFAM: SpoIVB peptidase S55; TIGRFAM: stage IV sporulation protein B YP_004462816.1 COGs: COG0193 Peptidyl-tRNA hydrolase; InterPro IPR001328: IPR018171; KEGG: cth:Cthe_2631 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_004462817.1 KEGG: amt:Amet_0159 hypothetical protein; SPTR: uncharacterized protein YP_004462818.1 COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterPro IPR014021: IPR001650: IPR014001: IPR004576: IPR 003711: IPR011545: IPR005118: IPR019793; KEGG: tex:Teth514_0593 transcription-repair coupling factor; PFAM: transcription factor CarD; DEAD/DEAH box helicase domain protein; helicase domain protein; TRCF domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd) YP_004462819.1 InterPro IPR000297; KEGG: cbe:Cbei_0087 peptidylprolyl isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PPIC-type PPIASE domain YP_004462820.1 InterPro IPR014213: IPR006339: IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain-containing protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T YP_004462821.1 COGs: COG0728 membrane protein virulence factor; InterPro IPR002797: IPR002528; KEGG: amt:Amet_0163 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; multi antimicrobial extrusion protein MatE; SPTR: Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B; Tat (twin-arginine translocation) pathway signal sequence YP_004462822.1 COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551: IPR004518; KEGG: cbb:CLD_0948 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_004462823.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: tte:TTE2453 nucleoid DNA-binding protein; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: Bacterial nucleoid DNA-binding protein; PFAM: Bacterial DNA-binding protein YP_004462824.1 COGs: COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); InterPro IPR002942; KEGG: ere:EUBREC_0528 hypothetical protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: S4 RNA-binding domain protein; PFAM: S4 domain YP_004462825.1 COGs: COG2385 Sporulation protein and related protein; InterPro IPR013486: IPR013693; KEGG: tte:TTE2451 sporulation protein and related proteins; PFAM: Stage II sporulation protein D; SPTR: Sporulation protein and related proteins; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain YP_004462826.1 InterPro IPR012504; KEGG: cth:Cthe_2659 YabP-like protein; PFAM: YabP family protein; SPTR: YabP-like protein; TIGRFAM: sporulation protein YabP; PFAM: YabP family; TIGRFAM: sporulation protein YqfC; sporulation protein YabP YP_004462827.1 InterPro IPR014242: IPR019074; KEGG: tjr:TherJR_0188 spore cortex biosynthesis protein YabQ; PFAM: Spore cortex biosynthesis protein, YabQ-like; SPTR: Spore cortex biosynthesis protein YabQ; TIGRFAM: spore cortex biosynthesis protein YabQ; PFAM: Spore cortex protein YabQ (Spore_YabQ); TIGRFAM: spore cortex biosynthesis protein YabQ YP_004462828.1 InterPro IPR007060; KEGG: cac:CA_C3207 hypothetical protein; PFAM: Septum formation initiator; SPTR: uncharacterized protein; PFAM: Septum formation initiator; TIGRFAM: cell division protein FtsL YP_004462829.1 COGs: COG1098 RNA binding protein (contains ribosomal protein S1 domain); InterPro IPR003029; KEGG: cth:Cthe_2662 RNA binding S1; PFAM: RNA binding S1 domain protein; SPTR: RNA binding S1 domain protein; PFAM: S1 RNA binding domain YP_004462830.1 COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135: IPR008136: IPR001453; KEGG: cth:Cthe_1052 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain YP_004462831.1 COGs: COG0468 RecA/RadA recombinase; InterPro IPR020588: IPR020587: IPR003593: IPR001553: IPR 013765: IPR020584; KEGG: tmt:Tmath_1220 RecA protein; PFAM: RecA domain protein; SMART: AAA ATPase; SPTR: Protein recA; TIGRFAM: recA protein; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_004462832.1 COGs: COG2137 conserved hypothetical protein; InterPro IPR003783; KEGG: rer:RER_27540 recombination regulator RecX; PFAM: regulatory protein RecX; SPTR: Regulatory protein RecX; PFAM: RecX family YP_004462833.1 COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: cth:Cthe_0945 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004462834.1 COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: cth:Cthe_0944 SMC protein-like protein; PFAM: SMC domain protein; SPTR: SMC domain protein YP_004462835.1 KEGG: cth:Cthe_0943 hypothetical protein; SPTR: uncharacterized protein YP_004462836.1 KEGG: cth:Cthe_1092 hypothetical protein; SPTR: uncharacterized protein YP_004462837.1 COGs: COG3808 Inorganic pyrophosphatase; InterPro IPR004131; KEGG: cpy:Cphy_1812 membrane-bound proton-translocating pyrophosphatase; PFAM: Inorganic H pyrophosphatase; PRIAM: Inorganic diphosphatase; SPTR: uncharacterized protein; TIGRFAM: V-type H(+)-translocating pyrophosphatase; PFAM: Inorganic H+ pyrophosphatase; TIGRFAM: vacuolar-type H(+)-translocating pyrophosphatase YP_004462838.1 COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: sno:Snov_3500 protein of unknown function DUF2088; PFAM: Protein of unknown function DUF2088; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088) YP_004462839.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: tex:Teth514_1942 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase YP_004462840.1 COGs: COG0282 Acetate kinase; InterPro IPR000890: IPR004372; KEGG: tte:TTE1481 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase; TIGRFAM: acetate kinase YP_004462841.1 COGs: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR000249; KEGG: ecz:ECS88_4661 conserved hypothetical protein with microcompartments protein domain; PFAM: microcompartments protein; SPTR: BMC domain protein; PFAM: BMC domain YP_004462842.1 COGs: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR000249: IPR020808; KEGG: cpy:Cphy_1182 microcompartments protein; PFAM: microcompartments protein; SPTR: Carbon dioxide concentrating mechanism/carboxysome shell protein; PFAM: BMC domain YP_004462843.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: pam:PANA_2380 FbaA; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004462844.1 COGs: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR000249: IPR020808; KEGG: cpy:Cphy_1182 microcompartments protein; PFAM: microcompartments protein; SPTR: Microcompartments protein; PFAM: BMC domain YP_004462845.1 COGs: COG4869 Propanediol utilization protein; InterPro IPR008300; KEGG: cpy:Cphy_1183 propanediol utilization protein; PFAM: Propanediol utilization protein; SPTR: uncharacterized protein; PFAM: Propanediol utilisation protein PduL YP_004462846.1 COGs: COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR004992; KEGG: cpy:Cphy_1184 ethanolamine utilization protein EutN/carboxysome structural protein CcmL; PFAM: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; SPTR: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; PFAM: Ethanolamine utilisation protein EutN/carboxysome YP_004462847.1 COGs: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR000249: IPR020808; KEGG: tau:Tola_1691 microcompartments protein; PFAM: microcompartments protein; SPTR: Ribonuclease III; PFAM: BMC domain YP_004462848.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR012408: IPR015590; KEGG: tjr:TherJR_0630 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase YP_004462849.1 COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterPro IPR017054: IPR011538: IPR019554: IPR017900; KEGG: cbt:CLH_1845 ethanolamine utilization Fe-S center protein eut; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; SPTR: Ethanolamine utilization Fe-S center protein eut; PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004462850.1 COGs: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR011238: IPR000249; KEGG: drm:Dred_1303 microcompartments protein; PFAM: microcompartments protein; SPTR: Ethanolamine utilization protein eutM; PFAM: BMC domain YP_004462851.1 COGs: COG0282 Acetate kinase; InterPro IPR000890: IPR004372; KEGG: chy:CHY_1455 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase; TIGRFAM: acetate kinase YP_004462852.1 COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR012255: IPR014730: IPR000049; KEGG: amt:Amet_3749 electron transfer flavoprotein, alpha/beta-subunit-like protein; PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: Electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein domain YP_004462853.1 COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR001308: IPR014730: IPR014731: IPR018206; KEGG: amt:Amet_3748 electron transfer flavoprotein, alpha subunit-like protein; PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; SPTR: Electron transfer flavoprotein, alpha subunit-like protein; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain YP_004462854.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR004113: IPR000276; KEGG: tte:TTE0224 FAD/FMN-containing dehydrogenase; PFAM: FAD linked oxidase domain protein; SPTR: FAD linked oxidase domain protein; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_004462855.1 COGs: COG1283 Na+/phosphate symporter; InterPro IPR004633: IPR003841: IPR008170; KEGG: cbh:CLC_3388 Na/Pi-cotransporter family protein/PhoU family protein; PFAM: Na+/Picotransporter; PhoU family protein; SPTR: uncharacterized protein; TIGRFAM: Na/Pi-cotransporter II-related protein; PFAM: PhoU domain; Na+/Pi-cotransporter; TIGRFAM: Na/Pi-cotransporter YP_004462856.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR004654: IPR000600; KEGG: hor:Hore_16050 glucokinase; PFAM: ROK family protein; SPTR: Glucokinase; TIGRFAM: glucokinase, ROK family; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004462857.1 KEGG: cth:Cthe_3197 PRC-barrel domain-containing protein; SPTR: PRC-barrel domain protein; PFAM: PRC-barrel domain YP_004462858.1 KEGG: cbf:CLI_0478 hypothetical protein; SPTR: uncharacterized protein YP_004462859.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: amt:Amet_2457 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI YP_004462860.1 KEGG: pth:PTH_1565 hypothetical protein; SPTR: uncharacterized protein YP_004462861.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: ctc:CTC01433 RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004462862.1 KEGG: amt:Amet_1799 hypothetical protein; SPTR: uncharacterized protein YP_004462863.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: hmo:HM1_2210 DNA processing protein dpra, PFAM: SMF family protein; SPTR: DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_004462864.1 COGs: COG0550 Topoisomerase IA; InterPro IPR006154: IPR003601: IPR003602: IPR000380: IPR 005733: IPR006171: IPR013497: IPR013498; KEGG: cth:Cthe_0460 DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; DNA topoisomerase type IA zn finger domain protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I; PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_004462865.1 COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; InterPro IPR004417: IPR002218: IPR020595; KEGG: gwc:GWCH70_1103 gid protein; PFAM: glucose-inhibited division protein A; PRIAM:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:Methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferasetrmFO; TIGRFAM: gid protein; PFAM: Glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase YP_004462866.1 COGs: COG5405 ATP-dependent protease HslVU (ClpYQ) peptidase subunit; InterPro IPR001353; KEGG: tex:Teth514_1699 ATP-dependent protease peptidase subunit; PFAM: 20S proteasome A and B subunits; SPTR: 20S proteasome A and B subunits; PFAM: Proteasome subunit; TIGRFAM: ATP-dependent protease HslVU, peptidase subunit YP_004462867.1 COGs: COG1220 ATP-dependent protease HslVU (ClpYQ) ATPase subunit; InterPro IPR003593: IPR004491: IPR013093: IPR019489; KEGG: tjr:TherJR_1547 heat shock protein HslVU, ATPase subunit HslU; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent protease ATPase subunit HslU; TIGRFAM: heat shock protein HslVU, ATPase subunit HslU; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: ATP-dependent protease HslVU, ATPase subunit YP_004462868.1 COGs: COG4465 Pleiotropic transcriptional repressor; InterPro IPR014154: IPR010312: IPR013198; KEGG: cpr:CPR_1673 transcriptional repressor CodY; PFAM: GTP-sensing transcriptional pleiotropic repressor CodY; Helix-turn-helix CodY domain protein; SPTR: GTP-sensing transcriptional pleiotropic repressor CodY; TIGRFAM: GTP-sensing transcriptional pleiotropic repressor CodY; PFAM: CodY helix-turn-helix domain; CodY GAF-like domain; TIGRFAM: GTP-sensing transcriptional pleiotropic repressor CodY YP_004462869.1 COGs: COG1815 Flagellar basal body protein; InterPro IPR006300: IPR001444: IPR010930: IPR019776; KEGG: tpd:Teth39_1260 flagellar basal-body rod protein FlgB; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: Flagellar basal-body rod protein FlgB; TIGRFAM: flagellar basal-body rod protein FlgB; PFAM: Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgB YP_004462870.1 COGs: COG1558 Flagellar basal body rod protein; InterPro IPR006299: IPR001444: IPR010930; KEGG: slp:Slip_0951 flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar basal-body rod protein FlgC; TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC YP_004462871.1 COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: dhd:Dhaf_4151 flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex protein fliE; TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE YP_004462872.1 COGs: COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; InterPro IPR000067: IPR006182: IPR013556; KEGG: tmt:Tmath_1286 flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring domain protein; SPTR: Flagellar M-ring protein FliF; TIGRFAM: flagellar M-ring protein FliF; PFAM: Secretory protein of YscJ/FliF family; Flagellar M-ring protein C-terminal; TIGRFAM: flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) YP_004462873.1 COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: cce:Ccel_2050 flagellar motor switch protein G; PFAM: flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG YP_004462874.1 COGs: COG1317 Flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: tjr:TherJR_1540 flagellar assembly protein FliH/type III secretion system HrpE; PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; SPTR: Flagellar assembly protein FliH/Type III secretion system HrpE; PFAM: Flagellar assembly protein FliH YP_004462875.1 COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR003593: IPR005714: IPR004100: IPR000194: IPR 020003; KEGG: cce:Ccel_2048 ATPase FliI/YscN; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: ATPase, FliI/YscN family; TIGRFAM: ATPase, FliI/YscN family; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI YP_004462876.1 InterPro IPR012823; KEGG: cth:Cthe_0469 flagellar export protein FliJ; SPTR: Flagellar export protein FliJ; TIGRFAM: flagellar export protein FliJ; PFAM: Flagellar FliJ protein; TIGRFAM: flagellar export protein FliJ YP_004462877.1 InterPro IPR006668; KEGG: tpd:Teth39_1252 hypothetical protein; PFAM: MgtE intracellular region; SPTR: uncharacterized protein; PFAM: MgtE intracellular N domain YP_004462878.1 InterPro IPR021136; KEGG: bsu:BSU16270 flagellar hook-length control protein; PFAM: Flagellar hook-length control protein-like, C-terminal domain; SPTR: Flagellar hook-length control protein; PFAM: Flagellar hook-length control protein FliK YP_004462879.1 COGs: COG1843 Flagellar hook capping protein; InterPro IPR005648; KEGG: tit:Thit_1228 flagellar hook capping protein; PFAM: flagellar hook capping protein; SPTR: Flagellar hook capping protein; PFAM: Flagellar hook capping protein YP_004462880.1 InterPro IPR013367; KEGG: swo:Swol_0857 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: flagellar operon protein; PFAM: Protein of unknown function (DUF3766); TIGRFAM: flagellar operon protein YP_004462881.1 COGs: COG4786 Flagellar basal body rod protein; InterPro IPR020013: IPR001444: IPR010930; KEGG: bmq:BMQ_4185 flagellar hook protein FlgE; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar hook protein FlgE; TIGRFAM: fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria YP_004462882.1 COGs: COG1582 Uncharacterized protein possibly involved in motility; InterPro IPR009384; KEGG: csc:Csac_1267 flagellar FlbD family protein; PFAM: flagellar FlbD family protein; SPTR: Flagellar FlbD family protein; PFAM: Flagellar protein (FlbD) YP_004462883.1 COGs: COG1291 Flagellar motor component; InterPro IPR002898; KEGG: amt:Amet_2714 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; manually curated; PFAM: MotA/TolQ/ExbB proton channel family YP_004462884.1 COGs: COG1360 Flagellar motor protein; InterPro IPR006665; KEGG: hor:Hore_16770 OmpA/MotB domain protein; PFAM: OmpA/MotB domain protein; SPTR: OmpA/MotB domain protein; PFAM: OmpA family YP_004462885.1 COGs: COG1580 Flagellar basal body-associated protein; InterPro IPR005503; KEGG: tpd:Teth39_1246 flagellar basal body-associated protein FliL; PFAM: flagellar basal body-associated protein FliL; SPTR: Flagellar basal body-associated protein FliL; PFAM: Flagellar basal body-associated protein FliL YP_004462886.1 COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689: IPR001543; KEGG: cth:Cthe_0477 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM YP_004462887.1 COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172: IPR012826: IPR007597: IPR001543; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN YP_004462888.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cpy:Cphy_2701 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain YP_004462889.1 KEGG: tte:TTE1427 hypothetical protein; SPTR: uncharacterized protein; PFAM: Flagellar biosynthesis protein, FliO; TIGRFAM: flagellar biosynthetic protein FliO YP_004462890.1 COGs: COG1338 Flagellar biosynthesis pathway component FliP; InterPro IPR005838: IPR005837; KEGG: amt:Amet_2707 flagellar biosynthetic protein FliP; PFAM: type III secretion system inner membrane P protein; SPTR: Flagellar biosynthetic protein FliP; TIGRFAM: flagellar biosynthetic protein FliP; PFAM: FliP family; TIGRFAM: type III secretion apparatus protein, YscR/HrcR family; flagellar biosynthetic protein FliP YP_004462891.1 COGs: COG1987 Flagellar biosynthesis pathway component FliQ; InterPro IPR002191: IPR006305; KEGG: gym:GYMC10_4174 flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; SPTR: Flagellar biosynthetic protein FliQ; TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: Bacterial export proteins, family 3; TIGRFAM: flagellar biosynthetic protein FliQ YP_004462892.1 COGs: COG1684 Flagellar biosynthesis pathway component FliR; InterPro IPR002010: IPR006303; KEGG: cce:Ccel_2033 flagellar biosynthesis protein FliR; PFAM: type III secretion system inner membrane R protein; SPTR: Flagellar biosynthetic protein fliR; TIGRFAM: flagellar biosynthetic protein FliR; PFAM: Bacterial export proteins, family 1; TIGRFAM: flagellar biosynthetic protein FliR YP_004462893.1 COGs: COG1377 Flagellar biosynthesis pathway component FlhB; InterPro IPR006135: IPR006136; KEGG: tjr:TherJR_1523 flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; SPTR: Flagellar biosynthetic protein FlhB; TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flagellar biosynthetic protein FlhB YP_004462894.1 COGs: COG1298 Flagellar biosynthesis pathway component FlhA; InterPro IPR001712: IPR006301; KEGG: cth:Cthe_0485 flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; SPTR: Flagellar biosynthesis protein FlhA; TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: FHIPEP family; TIGRFAM: flagellar biosynthesis protein FlhA YP_004462895.1 COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR003593: IPR020006: IPR000897; KEGG: cth:Cthe_0486 GTP-binding signal recognition particle; PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: AAA ATPase; SPTR: GTP-binding signal recognition particle SRP54, G-domain; TIGRFAM: flagellar biosynthetic protein FlhF; PFAM: SRP54-type protein, GTPase domain; TIGRFAM: flagellar biosynthetic protein FlhF YP_004462896.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_0487 cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004462897.1 COGs: COG5581 glycosyltransferase; InterPro IPR009875; KEGG: cth:Cthe_0488 type IV pilus assembly PilZ; PFAM: type IV pilus assembly PilZ; SPTR: Type IV pilus assembly PilZ; PFAM: PilZ domain YP_004462898.1 COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: gka:GK1241 chemotaxis-specific methylesterase; PFAM: CheB methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: Chemotaxis response regulator protein-glutamate methylesterase; PFAM: CheB methylesterase YP_004462899.1 COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR005467: IPR002545: IPR008207: IPR003594: IPR 004358: IPR010808: IPR004105; KEGG: csc:Csac_1281 CheA signal transduction histidine kinase; PFAM: P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; ATP-binding region ATPase domain protein; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: CheA signal transduction histidine kinase; PFAM: P2 response regulator binding domain; CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain YP_004462900.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dhd:Dhaf_4154 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: uncharacterized protein; PFAM: CheW-like domain YP_004462901.1 COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: cth:Cthe_0492 CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; SPTR: CheC, inhibitor of MCP methylation; PFAM: CheC-like family YP_004462902.1 COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; InterPro IPR005659; KEGG: amt:Amet_2695 chemoreceptor glutamine deamidase CheD; PFAM: CheD family protein; SPTR: CheD; PFAM: CheD YP_004462903.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterPro IPR000943: IPR014284: IPR012845: IPR007627: IPR 007630; KEGG: tjr:TherJR_1512 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family YP_004462904.1 COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: cth:Cthe_0498 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF342) YP_004462905.1 KEGG: hmo:HM1_2253 hypothetical protein; SPTR: uncharacterized protein YP_004462906.1 KEGG: ssp:SSP0840 accessory gene regulator C; SPTR: uncharacterized protein YP_004462907.1 InterPro IPR003770; KEGG: cce:Ccel_2018 hypothetical protein; PFAM: aminodeoxychorismate lyase; SPTR: uncharacterized protein; PFAM: YceG-like family YP_004462908.1 COGs: COG3822 ABC-type sugar transport system auxiliary component; KEGG: dth:DICTH_0546 YdaE; PRIAM: D-lyxose ketol-isomerase; SPTR: D-lyxose ketol-isomerase YP_004462909.1 COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR000559: IPR020628; KEGG: dau:Daud_0118 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; PFAM: Formate--tetrahydrofolate ligase YP_004462910.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR006076; KEGG: dat:HRM2_30780 fusion protein, heterodisulfide reductase (HdrA) / ferredoxin (iron-sulfur-binding protein); PFAM: FAD dependent oxidoreductase; SPTR: fusion protein, heterodisulfide reductase (HdrA) / ferredoxin (Iron-sulfur-binding protein); PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004462911.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896: IPR003813: IPR017900; KEGG: dal:Dalk_2777 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit YP_004462912.1 KEGG: slp:Slip_1394 hypothetical protein; SPTR: uncharacterized protein; PFAM: Methylene-tetrahydrofolate reductase C terminal YP_004462913.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: slp:Slip_1393 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase YP_004462914.1 COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017896: IPR017900; KEGG: dak:DaAHT2_1634 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit C YP_004462915.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896: IPR013027: IPR002218: IPR001327: IPR 003953: IPR017900; KEGG: dae:Dtox_1277 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; glucose-inhibited division protein A; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD binding domain; Glucose inhibited division protein A YP_004462916.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dae:Dtox_1278 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit YP_004462917.1 InterPro IPR017896: IPR017900; KEGG: dae:Dtox_1279 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein YP_004462918.1 InterPro IPR017896: IPR017900; KEGG: dae:Dtox_1280 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004462919.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR017927: IPR001221: IPR012165: IPR008333: IPR 001433: IPR019480; KEGG: chy:CHY_0934 hydrogenase, gamma subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Hydrogenase, gamma subunit; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004462920.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR010969: IPR000192; KEGG: cdl:CDR20291_3530 selenocysteine lyase; PFAM: aminotransferase class V; SPTR: selenocysteine lyase; TIGRFAM: cysteine desulfurase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase YP_004462921.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ckr:CKR_2700 hypothetical protein; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family YP_004462922.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: pmo:Pmob_1094 chromate transporter; PFAM: Chromate transporter; SPTR: Chromate transporter; PFAM: Chromate transporter YP_004462923.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: ctc:CTC00661 chromate transport protein; PFAM: Chromate transporter; SPTR: uncharacterized protein; PFAM: Chromate transporter YP_004462924.1 COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; InterPro IPR005467: IPR003594: IPR004358; KEGG: mta:Moth_1579 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004462925.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cpy:Cphy_1954 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004462926.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003660: IPR003661: IPR003594: IPR 004358; KEGG: amt:Amet_2326 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004462927.1 COGs: COG5401 Spore germination protein; InterPro IPR019606; KEGG: cth:Cthe_2543 spore germination protein-like protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: Spore germination protein-like protein; PFAM: Sporulation and spore germination YP_004462928.1 COGs: COG5401 Spore germination protein; InterPro IPR019606; KEGG: tjr:TherJR_2573 lipoprotein LpqB, GerMN domain protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: Spore germination protein-like protein; PFAM: Sporulation and spore germination YP_004462929.1 COGs: COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; InterPro IPR003837; KEGG: tte:TTE0606 aspartyl/glutamyl-tRNA amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase C subunit; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; manually curated; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit YP_004462930.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR004412: IPR000120: IPR020556; KEGG: csc:Csac_0909 aspartyl/glutamyl-tRNA amidotransferase subunit A; PFAM: Amidase; SPTR: Glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, A subunit; PFAM: Amidase; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit YP_004462931.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); InterPro IPR004413: IPR006075: IPR018027: IPR017958; KEGG: ate:Athe_0762 aspartyl/glutamyl-tRNA amidotransferase subunit B; PFAM: GatB region; Asn/Gln amidotransferase; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit YP_004462932.1 COGs: COG5401 Spore germination protein; InterPro IPR019606; KEGG: aoe:Clos_0556 hypothetical protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: uncharacterized protein; PFAM: Sporulation and spore germination YP_004462933.1 COGs: COG0689 RNase PH; InterPro IPR002381: IPR001247: IPR015847: IPR018336; KEGG: cdl:CDR20291_3169 ribonuclease Ph; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: Ribonuclease PH/Ham1 protein; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease, domain 1; 3' exoribonuclease, domain 2; TIGRFAM: ribonuclease PH YP_004462934.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR002637: IPR020922; KEGG: cce:Ccel_1353 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; PFAM: Ham1 family protein; SPTR: Nucleoside-triphosphatase; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_004462935.1 COGs: COG0622 phosphoesterase; InterPro IPR000979: IPR004843: IPR020935; KEGG: pth:PTH_0793 phosphoesterase; PFAM: metallophosphoesterase; SPTR: Predicted phosphoesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family YP_004462936.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR001179: IPR005215: IPR008881: IPR008880; KEGG: cth:Cthe_2739 trigger factor; PFAM: trigger factor domain-containing protein; peptidylprolyl isomerase FKBP-type; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor YP_004462937.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907: IPR018215; KEGG: cth:Cthe_2740 ATP-dependent Clp protease proteolytic subunit; PFAM: peptidase S14 ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_004462938.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterPro IPR003593: IPR004487: IPR010603: IPR013093: IPR 019489; KEGG: cth:Cthe_2741 ATP-dependent protease ATP-binding subunit ClpX; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit clpX; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004462939.1 COGs: COG1067 ATP-dependent protease; InterPro IPR002078: IPR003593: IPR001984: IPR014251: IPR 003959: IPR008268; KEGG: pth:PTH_0806 ATP-dependent protease; PFAM: AAA ATPase central domain protein; PRIAM: Endopeptidase La; SMART: AAA ATPase; SPTR: Predicted ATP-dependent protease; TIGRFAM: ATP-dependent protease LonB; PFAM: ATPase associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease LonB YP_004462940.1 COGs: COG0218 GTPase; InterPro IPR019987: IPR002917; KEGG: amt:Amet_1073 ribosome biogenesis GTP-binding protein YsxC; PFAM: GTP-binding protein HSR1-related; SPTR: Probable GTP-binding protein engB; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain YP_004462941.1 COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; InterPro IPR004803: IPR002616; KEGG: cdf:CD2802 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming YP_004462942.1 COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: ate:Athe_0391 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit YP_004462943.1 KEGG: aoe:Clos_1720 hypothetical protein; SPTR: uncharacterized protein YP_004462944.1 KEGG: cce:Ccel_0533 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004462945.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197: IPR000385; KEGG: aoe:Clos_1718 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004462946.1 COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR005791: IPR003335; KEGG: amt:Amet_2348 protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Protein-export membrane protein SecD; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family YP_004462947.1 COGs: COG0341 Preprotein translocase subunit SecF; InterPro IPR003335: IPR005665; KEGG: cpr:CPR_1907 preprotein translocase subunit SecF; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: Protein-export membrane protein SecF; TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF YP_004462948.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667: IPR003156: IPR004610; KEGG: amt:Amet_2351 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ YP_004462949.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR000836: IPR005764; KEGG: ctc:CTC02200 adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Adenine phosphoribosyltransferase; TIGRFAM: adenine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase YP_004462950.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterPro IPR006674: IPR007685: IPR004095: IPR002912: IPR 003607: IPR004811; KEGG: tpd:Teth39_1028 (p)ppGpp synthetase I, SpoT/RelA; PFAM: RelA/SpoT domain protein; metal-dependent phosphohydrolase HD sub domain; TGS domain-containing protein; amino acid-binding ACT domain protein; PRIAM: GTP diphosphokinase; SMART: metal-dependent phosphohydrolase HD region; SPTR: (P)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: HD domain; TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004462951.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dae:Dtox_2285 beta-lactamase domain protein; SPTR: Metallo-beta-lactamase; PFAM: Metallo-beta-lactamase superfamily YP_004462952.1 KEGG: cat:CA2559_06590 DNA-binding response regulator, LuxR family protein; SPTR: uncharacterized protein YP_004462953.1 COGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR004516: IPR002314: IPR004154: IPR006195: IPR 015807; KEGG: tmt:Tmath_1086 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_004462954.1 COGs: COG0173 Aspartyl-tRNA synthetase; InterPro IPR004365: IPR004364: IPR004115: IPR006195: IPR 004524: IPR002312; KEGG: tpd:Teth39_1036 aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; GAD domain protein; SPTR: Aspartyl-tRNA synthetase; TIGRFAM: aspartyl-tRNA synthetase; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type YP_004462955.1 COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family YP_004462956.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1937 YP_004462957.1 COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC YP_004462958.1 COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain YP_004462959.1 COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085: IPR019798; KEGG: tit:Thit_1812 glycine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase YP_004462960.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959: IPR003593; KEGG: eel:EUBELI_01348 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: ATPase related to the helicase subunit of the Holliday junction resolvase; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus YP_004462961.1 KEGG: cth:Cthe_0420 dipicolinate synthase subunit A; SPTR: Dipicolinate synthase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; TIGRFAM: dipicolinic acid synthetase, A subunit YP_004462962.1 InterPro IPR003382: IPR014214; KEGG: drm:Dred_1942 dipicolinate synthase subunit B; PFAM: flavoprotein; SPTR: Flavoprotein; TIGRFAM: dipicolinic acid synthetase, B subunit; PFAM: Flavoprotein; TIGRFAM: dipicolinic acid synthetase, B subunit YP_004462963.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR002142; KEGG: cth:Cthe_1097 ATP-dependent Clp protease proteolytic subunit ClpP; PFAM: peptidase S49; SPTR: ATP-dependent Clp protease proteolytic subunit ClpP; PFAM: Clp protease YP_004462964.1 KEGG: tte:TTE1380 hypothetical protein; SPTR: uncharacterized protein YP_004462965.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543: IPR018541: IPR003593; KEGG: cth:Cthe_1095 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: Cell divisionFtsK/SpoIIIE; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family YP_004462966.1 COGs: COG0621 2-methylthioadenine synthetase; InterPro IPR013848: IPR007197: IPR000408: IPR020612: IPR 006638: IPR002792: IPR005840: IPR005839; KEGG: cno:NT01CX_2125 tRNA modifying protein; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Ribosomal protein S12 methylthiotransferase rimO; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme YliG, TIGR01125; RNA modification enzyme, MiaB family YP_004462967.1 COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570: IPR000462; KEGG: tte:TTE1376 phosphatidylglycerophosphate synthase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: Phosphatidylglycerophosphate synthase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004462968.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034: IPR014036: IPR001969: IPR018356; KEGG: ate:Athe_2392 transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004462969.1 COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: tjr:TherJR_1929 stationary-phase survival protein SurE; PFAM: Survival protein SurE; SPTR: Survival protein SurE; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE YP_004462970.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281: IPR001347; KEGG: clj:CLJU_c21350 RpiR family transcriptional regulator; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain YP_004462971.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078: IPR001345; KEGG: tte:TTE1346 phosphoglycerate mutase/fructose-2,6-bisphosphatase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase/fructose-2,6-bisphosphatase; manually curated; PFAM: Phosphoglycerate mutase YP_004462972.1 COGs: COG2081 flavoprotein; InterPro IPR004792: IPR013027; KEGG: cce:Ccel_1733 HI0933 family protein; PFAM: HI0933 family protein; SPTR: HI0933 family protein; PFAM: HI0933-like protein; TIGRFAM: flavoprotein, HI0933 family YP_004462973.1 KEGG: swo:Swol_1397 hypothetical protein; SPTR: uncharacterized protein YP_004462974.1 COGs: COG1372 Intein/homing endonuclease; InterPro IPR013509: IPR000788: IPR003587: IPR006141: IPR 004042: IPR013344: IPR006142; KEGG: dhd:Dhaf_0267 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: Ribonucleotide reductase large subunit domain protein; ribonucleotide reductase large subunit; SMART: Hedgehog/intein hint domain protein; SPTR: Ribonucleoside-diphosphate reductase; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: Ribonucleotide reductase, all-alpha domain; Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; intein N-terminal splicing region; intein C-terminal splicing region YP_004462975.1 InterPro IPR018540; KEGG: tmt:Tmath_0916 sporulation stage 0, Spo0E-like regulatory phosphatase; PFAM: Sporulation stage 0, Spo0E-like regulatory phosphatase; SPTR: uncharacterized protein; PFAM: Spo0E like sporulation regulatory protein YP_004462976.1 COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: cth:Cthe_2075 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein Cther_0578; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family YP_004462977.1 KEGG: aoe:Clos_1729 hypothetical protein; SPTR: uncharacterized protein YP_004462978.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967: IPR012907: IPR018044; KEGG: tpd:Teth39_1138 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain YP_004462979.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942: IPR006145: IPR018496: IPR000748; KEGG: tte:TTE1332 16S rRNA uridine-516 pseudouridylate synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase YP_004462980.1 COGs: COG0421 Spermidine synthase; InterPro IPR001045; KEGG: ate:Athe_1314 spermidine synthase; PFAM: Spermine synthase; SPTR: Spermidine synthase; TIGRFAM: spermidine synthase; PFAM: Spermine/spermidine synthase; TIGRFAM: spermidine synthase YP_004462981.1 COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase; InterPro IPR006035: IPR005925; KEGG: cth:Cthe_0695 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: Agmatinase; TIGRFAM: agmatinase; PFAM: Arginase; TIGRFAM: agmatinase YP_004462982.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022: IPR011762: IPR011763: IPR000438; KEGG: tte:TTE1220 acetyl-CoA carboxylase alpha subunit; PFAM: carboxyl transferase; SPTR: Acetyl-CoA carboxylase alpha subunit; PFAM: Carboxyl transferase domain; TIGRFAM: methylmalonyl-CoA decarboxylase alpha subunit YP_004462983.1 InterPro IPR005899; KEGG: amt:Amet_4537 sodium pump decarboxylase, gamma subunit; PFAM: sodium pump decarboxylase gamma subunit; SPTR: Oxaloacetate decarboxylase gamma chain; TIGRFAM: sodium pump decarboxylase, gamma subunit; PFAM: Oxaloacetate decarboxylase, gamma chain; TIGRFAM: sodium pump decarboxylases, gamma subunit YP_004462984.1 COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089: IPR001882; KEGG: cth:Cthe_0700 biotin/lipoyl attachment protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: Biotin/lipoyl attachment domain-containing protein; PFAM: Biotin-requiring enzyme YP_004462985.1 COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: tpd:Teth39_0907 sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Glutaconyl-CoA decarboxylase; SPTR: uncharacterized protein; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit YP_004462986.1 COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891: IPR003379; KEGG: tit:Thit_1131 conserved carboxylase region; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; SPTR: Conserved carboxylase region; PFAM: HMGL-like; Conserved carboxylase domain YP_004462987.1 InterPro IPR000032; KEGG: csc:Csac_1846 hypothetical protein; SPTR: uncharacterized protein; PFAM: PTS HPr component phosphorylation site YP_004462988.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140: IPR003439: IPR017871: IPR003593: IPR 017940; KEGG: csc:Csac_0522 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter YP_004462989.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140: IPR003439: IPR017871: IPR003593: IPR 017940; KEGG: dth:DICTH_0477 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004462990.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cdl:CDR20291_2119 MarR-family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR-family transcriptional regulator; PFAM: MarR family YP_004462991.1 COGs: COG3580 conserved hypothetical protein; KEGG: amt:Amet_1169 hypothetical protein; SPTR: uncharacterized protein; PFAM: CoA enzyme activase uncharacterised domain (DUF2229) YP_004462992.1 COGs: COG3581 conserved hypothetical protein; KEGG: cth:Cthe_0353 hypothetical protein; SPTR: uncharacterized protein; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; CoA enzyme activase uncharacterised domain (DUF2229) YP_004462993.1 COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR002731: IPR008275; KEGG: chy:CHY_1411 CoA-substrate-specific enzyme activase domain-containing protein; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: BadF/BadG/BcrA/BcrD ATPase; TIGRFAM: CoA-substrate-specific enzyme activase YP_004462994.1 KEGG: csc:Csac_1501 hypothetical protein; SPTR: uncharacterized protein YP_004462995.1 KEGG: cce:Ccel_1441 hypothetical protein; SPTR: uncharacterized protein YP_004462996.1 COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616: IPR008532; KEGG: cth:Cthe_0581 fibronectin-binding A-like protein; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Fibronectin-binding A domain protein; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA) YP_004462997.1 COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527: IPR013551: IPR005229; KEGG: cth:Cthe_1317 hypothetical protein; PFAM: YicC-like domain-containing protein; domain of unknown function DUF1732; SPTR: YicC domain protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: conserved hypothetical protein TIGR00255 YP_004462998.1 COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF370) YP_004462999.1 COGs: COG0194 Guanylate kinase; InterPro IPR008144: IPR020590: IPR008145: IPR017665; KEGG: tpd:Teth39_1324 guanylate kinase; PFAM: guanylate kinase; PRIAM: Guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; SPTR: Guanylate kinase; TIGRFAM: guanylate kinase; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_004463000.1 COGs: COG1758 DNA-directed RNA polymerase subunit K/omega; InterPro IPR006110: IPR003716; KEGG: vpr:Vpar_0842 DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; SPTR: DNA-directed RNA polymerase subunit omega; TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_004463001.1 COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382: IPR007085: IPR005252; KEGG: cdf:CD2587 coenzyme A biosynthesis bifunctional protein; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; PRIAM: Phosphopantothenate--cysteine ligase; SPTR: Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_004463002.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterPro IPR011545: IPR001650: IPR014001: IPR014021: IPR 005259; KEGG: tpd:Teth39_1321 primosomal protein N'; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N' YP_004463003.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: tte:TTE1507 peptide deformylase; PFAM: formylmethionine deformylase; SPTR: Peptide deformylase; TIGRFAM: peptide deformylase; PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_004463004.1 COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376: IPR005793: IPR001555: IPR005794; KEGG: cce:Ccel_1529 methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: methionyl-tRNA formyltransferase; PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_004463005.1 COGs: COG2738 Zn-dependent protease; InterPro IPR007395; KEGG: tpd:Teth39_1317 peptidase, membrane zinc metallopeptidase, PFAM: peptidase membrane zinc metallopeptidase; SPTR: Peptidase, membrane zinc metallopeptidase, ; PFAM: neutral zinc metallopeptidase YP_004463006.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678: IPR004573; KEGG: cth:Cthe_0571 sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Sun protein; TIGRFAM: sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB YP_004463007.1 COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383: IPR007197; KEGG: ctc:CTC01223 florfenicol resistance protein; PFAM: Radical SAM domain protein; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM enzyme, Cfr family YP_004463008.1 COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045: IPR010822: IPR001932; KEGG: hmo:HM1_2137 protein serine/threonine phosphatase, PFAM: Protein phosphatase 2C-like; Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Protein serine/threonine phosphatase, ; PFAM: Protein phosphatase 2C YP_004463009.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442: IPR005543: IPR017441: IPR008271: IPR 020635: IPR002290: IPR000719; KEGG: tmt:Tmath_1356 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine protein kinase with PASTA sensor(S); PFAM: Protein kinase domain; PASTA domain YP_004463010.1 COGs: COG1162 GTPase; InterPro IPR004881: IPR010914; KEGG: tte:TTE1499 GTPase; PFAM: GTPase EngC; SPTR: ribosome biogenesis GTPase RsgA; TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A YP_004463011.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056: IPR010916; KEGG: amt:Amet_2777 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase; TIGRFAM: ribulose-phosphate 3-epimerase YP_004463012.1 COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371: IPR006282; KEGG: tte:TTE1497 thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; SPTR: Thiamine pyrophosphokinase; TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase YP_004463013.1 KEGG: ddi:DDB_G0271956 IBR zinc finger-containing protein; SPTR: uncharacterized protein YP_004463014.1 COGs: COG0227 Ribosomal protein L28; InterPro IPR001383; KEGG: cbf:CLI_2559 50S ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_004463015.1 COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: tjr:TherJR_2102 protein of unknown function DUF322; PFAM: protein of unknown function DUF322; SPTR: Alkaline shock protein; PFAM: Protein of unknown function (DUF322) YP_004463016.1 COGs: COG1200 RecG-like helicase; InterPro IPR004365: IPR011545: IPR001650: IPR014001: IPR 014021: IPR004609; KEGG: tte:TTE1492 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent DNA helicase RecG; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG YP_004463017.1 InterPro IPR001448: IPR018126; KEGG: tte:TTE1490 small, acid-soluble spore proteins, alpha/be; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type YP_004463018.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398: IPR002052; KEGG: tte:TTE1487 N6-adenine-specific methylase; PFAM: Conserved hypothetical protein CHP00095; SPTR: N6-adenine-specific methylase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family YP_004463019.1 COGs: COG0669 Phosphopantetheine adenylyltransferase; InterPro IPR004820: IPR002355: IPR001980: IPR004821; KEGG: ate:Athe_1227 phosphopantetheine adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Phosphopantetheine adenylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_004463020.1 KEGG: cth:Cthe_1275 H+-ATPase subunit H; SPTR: H+-ATPase subunit H; PFAM: HrpE protein YP_004463021.1 COGs: COG3314 conserved hypothetical protein; InterPro IPR011642: IPR014226; KEGG: tpd:Teth39_1298 nucleoside recognition domain-containing protein; PFAM: nucleoside recognition domain protein; SPTR: Sporulation integral membrane protein YlbJ; TIGRFAM: sporulation integral membrane protein YlbJ; PFAM: Nucleoside recognition; TIGRFAM: sporulation integral membrane protein YlbJ YP_004463022.1 COGs: COG1323 nucleotidyltransferase; InterPro IPR008513; KEGG: cth:Cthe_1301 hypothetical protein; PFAM: protein of unknown function DUF795; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF795) YP_004463023.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703: IPR003593; KEGG: cce:Ccel_2538 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities (AAA) YP_004463024.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: ate:Athe_0449 protein of unknown function DUF58; PFAM: protein of unknown function DUF58; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF58 YP_004463025.1 KEGG: gym:GYMC10_4008 hypothetical protein; SPTR: uncharacterized protein YP_004463026.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713: IPR013221: IPR004101: IPR005758; KEGG: tte:TTE2575 UDP-N-acetylmuramate--L-alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate/alanine ligase; manually curated; PFAM: Mur ligase, catalytic domain; Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; UDP-N-acetylmuramate--alanine ligase YP_004463027.1 InterPro IPR000064; KEGG: amt:Amet_0654 NLP/P60 protein; PFAM: NLP/P60 protein; SPTR: NLP/P60 protein; PFAM: NlpC/P60 family YP_004463028.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR015265: IPR000836: IPR010078; KEGG: clj:CLJU_c41800 transcriptional regulator; PFAM: purine repressor; phosphoribosyltransferase; SPTR: Purine operon repressor, PurR; TIGRFAM: pur operon repressor; PFAM: Phosphoribosyl transferase domain; Bacterial purine repressor, N-terminal; TIGRFAM: pur operon repressor, Bacillus subtilis type YP_004463029.1 COGs: COG2088 Uncharacterized protein involved in the regulation of septum location; InterPro IPR007170; KEGG: cth:Cthe_2628 hypothetical protein; PFAM: SpoVG family protein; SPTR: SpoVG family protein; PFAM: SpoVG YP_004463030.1 COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR005835: IPR001451: IPR018357: IPR005882; KEGG: cth:Cthe_2629 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; SPTR: Bifunctional protein glmU; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_004463031.1 COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR000842: IPR005946; KEGG: aoe:Clos_2645 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004463032.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: tte:TTE2532 Zn-dependent hydrolase; SPTR: Predicted Zn-dependent hydrolases of the beta-lactamase fold YP_004463033.1 KEGG: pth:PTH_2516 hypothetical protein; SPTR: uncharacterized protein YP_004463034.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR018365: IPR011923; KEGG: tit:Thit_0841 rod shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: rod shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA YP_004463035.1 COGs: COG1803 Methylglyoxal synthase; InterPro IPR004363: IPR011607: IPR018148; KEGG: csc:Csac_1874 methylglyoxal synthase; PFAM: MGS domain protein; PRIAM: Methylglyoxal synthase; SPTR: Methylglyoxal synthase; TIGRFAM: methylglyoxal synthase; PFAM: MGS-like domain; TIGRFAM: methylglyoxal synthase YP_004463036.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tpd:Teth39_1443 peptidase M23B; PFAM: Peptidase M23; SPTR: Peptidase M23; PFAM: Peptidase M23 YP_004463037.1 InterPro IPR008915: IPR000644; KEGG: pth:PTH_0826 Zn-dependent protease; PFAM: peptidase M50; CBS domain containing protein; SPTR: Peptidase M50; PFAM: CBS domain; Peptidase M50 YP_004463038.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197: IPR006638; KEGG: cth:Cthe_0156 radical SAM family protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM; PFAM: Radical SAM superfamily YP_004463039.1 COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: tpd:Teth39_1440 hypothetical protein; PFAM: Protein of unknown function DUF2344; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344) YP_004463040.1 COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: drm:Dred_0185 CarD family transcriptional regulator; PFAM: transcription factor CarD; SPTR: Transcriptional regulator, CarD family; PFAM: CarD-like/TRCF domain YP_004463041.1 COGs: COG4956 Integral membrane protein (PIN domain superfamily); InterPro IPR002716: IPR006596: IPR002792; KEGG: amt:Amet_4507 PilT domain-containing protein; PFAM: PilT protein domain protein; SMART: Nucleotide binding protein PINc; SPTR: PilT protein domain protein; PFAM: PIN domain YP_004463042.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967: IPR012907: IPR018044; KEGG: tmt:Tmath_0906 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain YP_004463043.1 KEGG: pfh:PFHG_04653 conserved hypothetical protein YP_004463045.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dae:Dtox_0787 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1 YP_004463046.1 COGs: COG0171 NAD synthase; InterPro IPR003694; KEGG: tma:TM0645 NH(3)-dependent NAD(+) synthetase, SPTR: NH(3)-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase YP_004463047.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: cbi:CLJ_B2920 cell envelope-related transcriptional attenuator domain protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator domain protein; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004463048.1 KEGG: swo:Swol_0963 hypothetical protein; SPTR: uncharacterized protein YP_004463049.1 COGs: COG1734 DnaK suppressor protein; InterPro IPR000962: IPR014240; KEGG: amt:Amet_2798 TraR/DksA family transcriptional regulator; SPTR: Transcriptional regulator, TraR/DksA family; TIGRFAM: sporulation protein, yteA family; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: sporulation protein, yteA family; RNA polymerase-binding protein DksA YP_004463050.1 COGs: COG0597 Lipoprotein signal peptidase; InterPro IPR001872; KEGG: tmt:Tmath_1391 lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: lipoprotein signal peptidase; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_004463051.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006145: IPR006224: IPR006225; KEGG: tit:Thit_1342 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family YP_004463052.1 InterPro IPR003728: IPR020790; KEGG: tex:Teth514_1649 hypothetical protein; PFAM: protein of unknown function DUF150; SPTR: Ribosome maturation factor rimP; PFAM: Uncharacterised BCR, YhbC family COG0779 YP_004463053.1 COGs: COG0195 Transcription elongation factor; InterPro IPR013735: IPR003029: IPR004044: IPR004087: IPR 004088: IPR010213; KEGG: tjr:TherJR_1374 transcription termination factor NusA; PFAM: NusA domain-containing protein; RNA binding S1 domain protein; KH type 2 domain protein; SMART: KH domain protein; SPTR: Transcription termination factor NusA; TIGRFAM: transcription termination factor NusA; PFAM: NusA N-terminal domain; S1 RNA binding domain; TIGRFAM: transcription termination factor NusA YP_004463054.1 COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: cbi:CLJ_B2645 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF448) YP_004463055.1 COGs: COG0532 Translation initiation factor 2 (IF-2; GTPase); InterPro IPR006847: IPR000795: IPR004161: IPR000178: IPR 005225; KEGG: ate:Athe_1051 translation initiation factor IF-2; PFAM: protein synthesis factor GTP-binding; translation initiation factor IF-2 domain-containing protein; elongation factor Tu domain 2 protein; SPTR: Translation initiation factor IF-2; TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Translation-initiation factor 2; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_004463056.1 COGs: COG0858 Ribosome-binding factor A; InterPro IPR000238: IPR020053; KEGG: cth:Cthe_0990 ribosome-binding factor A; PFAM: ribosome-binding factor A; SPTR: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_004463057.1 COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain YP_004463058.1 COGs: COG0130 Pseudouridine synthase; InterPro IPR002501: IPR002478: IPR014780; KEGG: cth:Cthe_0988 tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; SPTR: tRNA pseudouridine synthase B; TIGRFAM: tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase YP_004463059.1 COGs: COG0196 FAD synthase; InterPro IPR002606: IPR015864: IPR015865; KEGG: tpd:Teth39_1205 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase YP_004463060.1 COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR000589: IPR005290; KEGG: mta:Moth_1055 SSU ribosomal protein S15P; PFAM: ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: ribosomal protein S15; PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_004463061.1 COGs: COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); InterPro IPR012162: IPR001247: IPR015847: IPR015848: IPR 018111: IPR003029: IPR004087: IPR004088; KEGG: tmt:Tmath_1232 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding; K Homology, type 1, subgroup; RNA binding S1 domain protein; PRIAM: Polyribonucleotide nucleotidyltransferase; SMART: KH domain protein; SPTR: Polyribonucleotide nucleotidyltransferase; TIGRFAM: polyribonucleotide nucleotidyltransferase; manually curated; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease, domain 1; 3' exoribonuclease, domain 2; Polyribonucleotide nucleotidyltransferase, RNA binding domain; TIGRFAM: polyribonucleotide nucleotidyltransferase YP_004463062.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: tmt:Tmath_1231 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; PFAM: Polysaccharide deacetylase YP_004463063.1 InterPro IPR017275; KEGG: cth:Cthe_0938 fatty acid biosynthesis transcriptional regulator; SPTR: Regulatory protein, DeoR YP_004463064.1 COGs: COG0416 Fatty acid/phospholipid biosynthesis enzyme; InterPro IPR012281: IPR003664; KEGG: aoe:Clos_1451 glycerol-3-phosphate acyltransferase PlsX; PFAM: fatty acid synthesis plsX protein; SPTR: Phosphate acyltransferase; TIGRFAM: fatty acid/phospholipid synthesis protein PlsX; PFAM: Fatty acid synthesis protein; TIGRFAM: fatty acid/phospholipid synthesis protein PlsX YP_004463065.1 COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR013751: IPR013747: IPR004655; KEGG: tte:TTE1475 3-oxoacyl-(acyl carrier protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 3; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III YP_004463066.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136: IPR017569; KEGG: tmt:Tmath_1332 enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase NPD; SPTR: Enoyl-(Acyl-carrier-protein) reductase II; TIGRFAM: enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase; TIGRFAM: enoyl-(acyl-carrier-protein) reductase II YP_004463067.1 COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043: IPR004410; KEGG: tte:TTE1473 acyl-carrier-protein S-malonyltransferase; PFAM: Acyl transferase; SPTR: (Acyl-carrier-protein) S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase YP_004463068.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR020904: IPR011284: IPR002347; KEGG: cyc:PCC7424_2848 3-ketoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-(Acyl-carrier-protein) reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_004463069.1 COGs: COG0236 Acyl carrier protein; InterPro IPR006163: IPR006162: IPR009081: IPR001633: IPR 003231; KEGG: tmt:Tmath_1329 acyl carrier protein; PFAM: phosphopantetheine-binding; SPTR: Acyl carrier protein; TIGRFAM: acyl carrier protein; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_004463070.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030: IPR014031: IPR018201: IPR017568; KEGG: aoe:Clos_1457 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; SPTR: 3-oxoacyl-(Acyl-carrier-protein) synthase 2; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004463071.1 COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR000999: IPR001159: IPR011907; KEGG: adg:Adeg_0961 ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; PRIAM: Ribonuclease III; SMART: ribonuclease III; double-stranded RNA binding domain protein; SPTR: Ribonuclease III; TIGRFAM: ribonuclease III; manually curated; PFAM: RNase3 domain; Double-stranded RNA binding motif; TIGRFAM: ribonuclease III, bacterial YP_004463072.1 COGs: COG1243 Histone acetyltransferase; InterPro IPR007197: IPR006638; KEGG: tte:TTE1468 RNA polymerase II complex ELP3 subunit; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetyltransferase domain (Only BioB/LipA-like domain in Thermotoga); PFAM: Radical SAM superfamily YP_004463073.1 COGs: COG1196 Chromosome segregation ATPase; InterPro IPR003395: IPR010935: IPR011890; KEGG: cce:Ccel_0696 chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain-containing protein; SPTR: Chromosome segregation protein SMC; TIGRFAM: chromosome segregation protein SMC; PFAM: RecF/RecN/SMC N terminal domain; SMC proteins Flexible Hinge Domain; TIGRFAM: chromosome segregation protein SMC, common bacterial type YP_004463074.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR013822: IPR000897: IPR003593: IPR004390; KEGG: clj:CLJU_c12860 cell division protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; SPTR: Signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_004463075.1 COGs: COG2739 conserved hypothetical protein; InterPro IPR007394; KEGG: cbt:CLH_1195 DNA-binding protein; PFAM: helix-turn-helix protein YlxM/p13 family protein; SPTR: helix-turn-helix protein YlxM/p13 family protein; PFAM: helix-turn-helix protein, YlxM / p13 like YP_004463076.1 COGs: COG0541 Signal recognition particle GTPase; InterPro IPR013822: IPR013079: IPR000897: IPR004125: IPR 003593: IPR004780; KEGG: aoe:Clos_1463 signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; 6-phosphofructo-2-kinase; Signal peptide binding (SRP54) M- domain protein; SMART: AAA ATPase; SPTR: Signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein YP_004463077.1 COGs: COG0228 Ribosomal protein S16; InterPro IPR000307: IPR020592; KEGG: bbe:BBR47_36170 30S ribosomal protein S16; PFAM: ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: ribosomal protein S16; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_004463078.1 COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR004088: IPR020627; KEGG: tmt:Tmath_1304 hypothetical protein; SPTR: uncharacterized protein YP_004463079.1 COGs: COG0806 RimM protein required for 16S rRNA processing; InterPro IPR002676: IPR007903: IPR011961; KEGG: ctc:CTC01250 16S rRNA-processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; SPTR: Ribosome maturation factor rimM; TIGRFAM: 16S rRNA processing protein RimM; PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_004463080.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; InterPro IPR002649: IPR016009; KEGG: aoe:Clos_1467 tRNA (guanine-N(1)-)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_004463081.1 COGs: COG0335 Ribosomal protein L19; InterPro IPR001857: IPR018257; KEGG: tjr:TherJR_2043 ribosomal protein L19; PFAM: ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: ribosomal protein L19; PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_004463082.1 COGs: COG0681 Signal peptidase I; InterPro IPR019759: IPR019756: IPR019757: IPR019758: IPR 000223; KEGG: bts:Btus_1456 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004463083.1 COGs: COG1161 GTPase; InterPro IPR016478: IPR002917: IPR019991: IPR006073; KEGG: tpd:Teth39_1271 GTP-binding protein, HSR1-related; PFAM: GTP-binding protein HSR1-related; SPTR: Ribosome biogenesis GTP-binding protein YlqF; TIGRFAM: ribosome biogenesis GTP-binding protein YlqF; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YlqF; small GTP-binding protein domain YP_004463084.1 COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: cth:Cthe_0761 ribonuclease HII; PFAM: ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease; PFAM: Ribonuclease HII YP_004463085.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: tex:Teth514_1703 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein Teth514_1703; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252 YP_004463086.1 COGs: COG0606 ATPase with chaperone activity; InterPro IPR000523: IPR003593: IPR004482; KEGG: tpd:Teth39_1270 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein YP_004463087.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cce:Ccel_0200 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463088.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: cce:Ccel_0201 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463089.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cce:Ccel_0202 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463090.1 COGs: COG2730 Endoglucanase; InterPro IPR001547; KEGG: dge:Dgeo_2693 glycoside hydrolase; PFAM: glycoside hydrolase 5; SPTR: Glycoside hydrolase, family 5; PFAM: Cellulase (glycosyl hydrolase 5) YP_004463091.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR010559: IPR003594: IPR005467; KEGG: cbe:Cbei_4963 integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004463092.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR000005: IPR018060; KEGG: cce:Ccel_0198 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463093.1 COGs: COG3828 conserved hypothetical protein; KEGG: bha:BH0709 hypothetical protein; SPTR: BH0709 protein; PFAM: Trehalose utilisation YP_004463094.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: rrs:RoseRS_3454 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004463095.1 InterPro IPR000111: IPR002241; KEGG: pjd:Pjdr2_4264 alpha-galactosidase; PFAM: glycoside hydrolase clan GH-D; PRIAM: Alpha-galactosidase; SPTR: Alpha-galactosidase; PFAM: Melibiase YP_004463096.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: bse:Bsel_0982 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463097.1 COGs: COG2119 membrane protein; InterPro IPR001727; KEGG: amt:Amet_4329 hypothetical protein; PFAM: protein of unknown function UPF0016; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0016 YP_004463098.1 COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144: IPR012833; KEGG: ate:Athe_0548 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone domain protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase YP_004463099.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197: IPR012840; KEGG: tmt:Tmath_1650 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein YP_004463100.1 COGs: COG2038 NaMN:DMB phosphoribosyltransferase; InterPro IPR003200: IPR017846; KEGG: hmo:HM1_2401 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (nn:dbi prt) (n(1)-alpha-phosphoribosyltransferase); PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; PRIAM: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; SPTR: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM:nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_004463101.1 COGs: COG2116 Formate/nitrite family of transporter; InterPro IPR000292; KEGG: tde:TDE0999 formate/nitrite transporter; PFAM: formate/nitrite transporter; SPTR: Formate/nitrite transporter; TIGRFAM: formate/nitrite transporter; PFAM: Formate/nitrite transporter; TIGRFAM: formate/nitrite transporter YP_004463102.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018771: IPR000005: IPR018062: IPR018060: IPR 020449; KEGG: tjr:TherJR_0051 transcriptional regulator, AraC family; PFAM: Transcription regulator,histidine kinase sensor-like; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Predicted histidine kinase sensor domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463103.1 COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: tjr:TherJR_0059 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; PRIAM: Methionine synthase; SPTR: Dihydropteroate synthase DHPS; PFAM: Pterin binding enzyme YP_004463104.1 COGs: COG5012 cobalamin binding protein; InterPro IPR003759: IPR006158: IPR012741; KEGG: dth:DICTH_0565 trimethylamine corrinoid protein 2; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Trimethylamine corrinoid protein 2; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain YP_004463105.1 InterPro IPR004223; KEGG: tte:TTE1028 hypothetical protein; PFAM: Vitamin B12 dependent methionine synthase activation region; SPTR: Vitamin B12 dependent methionine synthase activation region; PFAM: Vitamin B12 dependent methionine synthase, activation domain YP_004463106.1 COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: clj:CLJU_c07530 metal-binding protein; PFAM: ferredoxin; SPTR: Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain YP_004463107.1 COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: amt:Amet_3039 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase YP_004463108.1 COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: tpd:Teth39_1135 hypothetical protein; PFAM: protein of unknown function DUF107; SPTR: uncharacterized protein; PFAM: Serine dehydrogenasease; NfeD-like; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_004463109.1 COGs: COG4864 conserved hypothetical protein; KEGG: drm:Dred_2488 hypothetical protein; SPTR: uncharacterized protein; PFAM: SigmaW regulon antibacterial YP_004463110.1 KEGG: cin:100185354 similar to La ribonucleoprotein domain family, member 1 (predicted); SPTR: Increased rDNA silencing protein 4 YP_004463111.1 KEGG: amt:Amet_3035 hypothetical protein; SPTR: uncharacterized protein; PFAM: YabP family; TIGRFAM: sporulation protein YqfC YP_004463112.1 InterPro IPR010690; KEGG: tmt:Tmath_0960 sporulation protein YqfD; PFAM: stage IV sporulation YqfD; SPTR: Sporulation protein YqfD; TIGRFAM: sporulation protein YqfD; manually curated; PFAM: stage IV sporulation protein YqfD; TIGRFAM: sporulation protein YqfD YP_004463113.1 COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: tex:Teth514_1340 PhoH family protein; PFAM: PhoH family protein; SPTR: PhoH family protein; PFAM: PhoH-like protein YP_004463114.1 COGs: COG0319 metal-dependent hydrolase; InterPro IPR002036; KEGG: cby:CLM_3343 metalloprotease; PFAM: protein of unknown function UPF0054; SPTR: metalloprotease TtheDRAFT_2187; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family YP_004463115.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125: IPR016192: IPR006262; KEGG: trq:TRQ2_0081 cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_004463116.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: gym:GYMC10_6024 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; manually curated; PFAM: Major Facilitator Superfamily YP_004463117.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR001958; KEGG: hor:Hore_15060 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004463118.1 InterPro IPR013429: IPR006058; KEGG: ate:Athe_2603 regulatory protein, FmdB family; PFAM: regulatory protein FmdB; SPTR: Regulatory protein, FmdB family; TIGRFAM: regulatory protein, FmdB family; PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family YP_004463119.1 COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: tmt:Tmath_0418 adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobinamide-phosphate guanylyltransferase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase YP_004463120.1 COGs: COG0368 Cobalamin-5-phosphate synthase; InterPro IPR003805; KEGG: cno:NT01CX_2079 cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; SPTR: Cobalamin synthase; TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase YP_004463121.1 COGs: COG4813 Trehalose utilization protein; InterPro IPR009381; KEGG: hvo:HVO_1459 trehalose utilization protein; SPTR: Trehalose utilization protein; PFAM: Trehalose utilisation YP_004463122.1 KEGG: tpd:Teth39_0795 hypothetical protein; SPTR: uncharacterized protein YP_004463123.1 KEGG: tpd:Teth39_0784 hypothetical protein; SPTR: uncharacterized protein YP_004463124.1 COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: nth:Nther_1776 aminodeoxychorismate lyase; PFAM: aminodeoxychorismate lyase; SPTR: Aminodeoxychorismate lyase; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family YP_004463125.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460; KEGG: tit:Thit_1052 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain YP_004463126.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterPro IPR016263: IPR007627: IPR007630: IPR000943: IPR 014209: IPR014284; KEGG: tpd:Teth39_1064 sporulation sigma factor SigK; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-K factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-K factor YP_004463127.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: tmt:Tmath_0383 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004463128.1 COGs: COG3459 Cellobiose phosphorylase; InterPro IPR009342: IPR000169; KEGG: vsp:VS_II1386 cellodextrin-phosphorylase; PFAM: carbohydrate binding; SPTR: carbohydrate binding protein; PFAM: Glycosyltransferase 36; carbohydrate binding domain; Glycosyltransferase 36 associated family YP_004463129.1 InterPro IPR001701: IPR001956: IPR003961: IPR018221; KEGG: ate:Athe_1867 glycoside hydrolase 48; PFAM: glycoside hydrolase 9; type 3a cellulose-binding domain protein; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: Cellulase; PFAM: Cellulose binding domain; Glycosyl hydrolase 9; Fibronectin type III domain YP_004463130.1 InterPro IPR000556: IPR003961; KEGG: cth:Cthe_0071 cellulose 1,4-beta-cellobiosidase; PFAM: glycoside hydrolase 48; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: Cellulose 1,4-beta-cellobiosidase; PFAM: Glycosyl hydrolase 48; Fibronectin type III domain YP_004463131.1 InterPro IPR001547: IPR003961: IPR018087; KEGG: csc:Csac_1077 glycoside hydrolase; PFAM: glycoside hydrolase 5; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: Glycoside hydrolase, family 5; PFAM: Cellulase (glycosyl hydrolase 5); Fibronectin type III domain YP_004463132.1 InterPro IPR001547: IPR018087; KEGG: scl:sce4910 cellulase; PFAM: glycoside hydrolase 5; PRIAM: Cellulase; SPTR: Cellulase; PFAM: Cellulase (glycosyl hydrolase 5) YP_004463133.1 COGs: COG2730 Endoglucanase; InterPro IPR001547: IPR005102: IPR003961: IPR018087; KEGG: gym:GYMC10_1332 cellulase; PFAM: glycoside hydrolase 5; protein of unknown function DUF291; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: Cel5B; PFAM: Domain of unknown function; Cellulase (glycosyl hydrolase 5); Fibronectin type III domain YP_004463134.1 COGs: COG3693 Beta-1 4-xylanase; InterPro IPR001000: IPR003961; KEGG: cac:CA_P0116 xylanase; PFAM: glycoside hydrolase 10; Fibronectin type III domain protein; SMART: glycoside hydrolase 10; Fibronectin type III domain protein; SPTR: Xylanase; PFAM: Glycosyl hydrolase 10; Fibronectin type III domain YP_004463135.1 COGs: COG2730 Endoglucanase; InterPro IPR001547: IPR003961; KEGG: cai:Caci_4214 glycoside hydrolase 5; PFAM: glycoside hydrolase 5; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: Glycoside hydrolase 5; PFAM: Cellulase (glycosyl hydrolase 5); Fibronectin type III domain YP_004463136.1 InterPro IPR001701: IPR001956: IPR003961: IPR018221; KEGG: hut:Huta_2399 glycoside hydrolase 9; PFAM: glycoside hydrolase 9; type 3a cellulose-binding domain protein; Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: Glycoside hydrolase 9; PFAM: Cellulose binding domain; Glycosyl hydrolase 9; Fibronectin type III domain YP_004463137.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; KEGG: eel:EUBELI_20530 hypothetical protein; SPTR: uncharacterized protein YP_004463138.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_5597 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463139.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_5596 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport system inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463140.1 COGs: COG2179 hydrolase of the HAD superfamily; InterPro IPR005834: IPR010021: IPR006549; KEGG: swo:Swol_0523 HAD family phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily phosphatase subfamily IIIA; TIGRFAM: HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Protein of unknown function; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 YP_004463141.1 COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR013708: IPR006151: IPR011342; KEGG: mta:Moth_1558 shikimate dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase YP_004463142.1 InterPro IPR012902: IPR001120: IPR000983; KEGG: apr:Apre_0649 hypothetical protein; SPTR: Type IV pilin protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain YP_004463143.1 KEGG: hor:Hore_06020 hypothetical protein; SPTR: uncharacterized protein YP_004463144.1 InterPro IPR012902; KEGG: smt:Smal_0550 type II secretory pathway pseudopilin; SPTR: Type II secretory pathway pseudopilin; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004463145.1 InterPro IPR012902: IPR001120; KEGG: dau:Daud_0961 hypothetical protein; SPTR: uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004463146.1 COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883; KEGG: amt:Amet_3474 type IV pilus assembly protein PilM; SPTR: Type IV pilus assembly protein PilM; TIGRFAM: type IV pilus assembly protein PilM; PFAM: MreB/Mbl protein; Competence protein A; TIGRFAM: type IV pilus assembly protein PilM YP_004463147.1 InterPro IPR007813; KEGG: cps:CPS_0468 type IV pilus biogenesis protein PilN; PFAM: Fimbrial assembly family protein; SPTR: Type IV pilus biogenesis protein PilN; PFAM: Fimbrial assembly protein (PilN) YP_004463148.1 KEGG: tte:TTE1274 fimbrial assembly protein; SPTR: Fimbrial assembly protein; PFAM: General secretion pathway, M protein YP_004463149.1 COGs: COG0703 Shikimate kinase; InterPro IPR000623; KEGG: tte:TTE1275 shikimate kinase; PFAM: shikimate kinase; PRIAM: Shikimate kinase; SPTR: Shikimate kinase; PFAM: Shikimate kinase YP_004463150.1 COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR001482: IPR003593: IPR006321; KEGG: tte:TTE1263 pili biogenesis protein PilT-like ATPase; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Predicted ATPases involved in pili biogenesis, PilT homologs; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT YP_004463151.1 COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831: IPR001482: IPR003593; KEGG: tte:TTE1262 pili biogenesis protein PilB-like ATPase; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; SPTR: Predicted ATPases involved in pili biogenesis, PilB homologs; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: general secretory pathway protein E YP_004463152.1 COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076: IPR001992: IPR003004; KEGG: amt:Amet_3480 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain YP_004463153.1 COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR010627: IPR000045: IPR014032; KEGG: gur:Gura_1800 peptidase A24A domain-containing protein; PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; PRIAM: Prepilin peptidase; SPTR: Peptidase A24A domain protein; PFAM: Bacterial Peptidase A24 N-terminal domain; Type IV leader peptidase YP_004463154.1 InterPro IPR012902; KEGG: slp:Slip_0396 pilin assembly protein; SPTR: Pilin assembly protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004463155.1 InterPro IPR012902; KEGG: tpd:Teth39_1073 hypothetical protein; SPTR: uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004463156.1 InterPro IPR012902; KEGG: tpd:Teth39_1074 hypothetical protein; SPTR: uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004463157.1 KEGG: aoe:Clos_0607 hypothetical protein; SPTR: uncharacterized protein YP_004463158.1 InterPro IPR019657; KEGG: tte:TTE1271 hypothetical protein; PFAM: Late competence development protein ComFB; SPTR: uncharacterized protein; PFAM: Late competence development protein ComFB YP_004463159.1 COGs: COG0648 Endonuclease IV; InterPro IPR012307: IPR001719; KEGG: tpd:Teth39_1081 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SMART: AP endonuclease 2; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463160.1 COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638: IPR004393; KEGG: cth:Cthe_2354 nicotinate-nucleotide pyrophosphorylase [carboxylating]; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase YP_004463161.1 COGs: COG0029 Aspartate oxidase; InterPro IPR003953: IPR004112: IPR005288: IPR013027; KEGG: cth:Cthe_2355 L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: domain; FAD binding domain; TIGRFAM: L-aspartate oxidase YP_004463162.1 COGs: COG0379 Quinolinate synthase; InterPro IPR003473; KEGG: tjr:TherJR_0217 quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A; PRIAM: Quinolinate synthase; SPTR: Quinolinate synthetase complex, A subunit; TIGRFAM: quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A protein; TIGRFAM: quinolinate synthetase complex, A subunit YP_004463163.1 KEGG: ate:Athe_1147 hypothetical protein; SPTR: uncharacterized protein YP_004463164.1 COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: cce:Ccel_3192 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase YP_004463165.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: cth:Cthe_1252 auxin efflux carrier; PFAM: Auxin Efflux Carrier; SPTR: Auxin Efflux Carrier; PFAM: Membrane transport protein YP_004463166.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR003135: IPR013221: IPR004101: IPR011761: IPR 011810; KEGG: tte:TTE2785 cyanophycin synthetase; PFAM: Mur ligase middle domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramyl tripeptide synthase; TIGRFAM: cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; cyanophycin synthetase YP_004463167.1 COGs: COG4242 Cyanophycinase and related exopeptidase; InterPro IPR011811: IPR005320; KEGG: tmt:Tmath_2271 cyanophycinase; PFAM: peptidase S51 dipeptidase E; PRIAM: Cyanophycinase; SPTR: Cyanophycinase; TIGRFAM: cyanophycinase; PFAM: Peptidase S51; TIGRFAM: cyanophycinase YP_004463168.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: tmt:Tmath_2153 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004463169.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_0892 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463170.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: gym:GYMC10_0893 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463171.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_0894 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463172.1 COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterPro IPR011538: IPR019554: IPR017900: IPR017896: IPR 010208; KEGG: amt:Amet_2280 electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; SPTR: Electron transport complex, RnfABCDGE type, C subunit; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit YP_004463173.1 COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; InterPro IPR004338: IPR011303; KEGG: tit:Thit_0113 electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein; SPTR: Electron transport complex, RnfABCDGE type, D subunit; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit YP_004463174.1 COGs: COG4659 NADH:ubiquinone oxidoreductase subunit RnfG; InterPro IPR007329: IPR010209; KEGG: cbf:CLI_0442 electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain protein; SPTR: Electron transport complex, RnfABCDGE type, G subunit; TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, G subunit YP_004463175.1 COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; InterPro IPR003667: IPR010968; KEGG: tpd:Teth39_2121 electron transport complex, RnfABCDGE type, E subunit; PFAM: RnfA-Nqr electron transport subunit; SPTR: Electron transport complex, RnfABCDGE type, E subunit; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit YP_004463176.1 COGs: COG4657 NADH:ubiquinone oxidoreductase subunit RnfA; InterPro IPR003667: IPR011293; KEGG: aoe:Clos_1771 electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; SPTR: RnfA; TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, A subunit YP_004463177.1 COGs: COG2878 NADH:ubiquinone oxidoreductase subunit RnfB; InterPro IPR007202: IPR017900: IPR017896: IPR010207; KEGG: amt:Amet_2285 electron transport complex, RnfABCDGE type, B subunit; PFAM: Fe-S cluster domain protein; SPTR: Electron transport complex, RnfABCDGE type, B subunit; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; PFAM: Fe-S cluster; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit YP_004463178.1 COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602: IPR018234: IPR001474; KEGG: tjr:TherJR_1931 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_004463179.1 InterPro IPR006674: IPR003607: IPR006675; KEGG: amt:Amet_2156 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004463180.1 COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489: IPR006390; KEGG: clj:CLJU_c06340 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_004463181.1 COGs: COG1539 Dihydroneopterin aldolase; InterPro IPR006157: IPR019793: IPR006156; KEGG: cno:NT01CX_0374 bifunctional folate synthesis protein; PFAM: dihydroneopterin aldolase; PRIAM: Dihydroneopterin aldolase; SPTR: Bifunctional folate synthesis protein; TIGRFAM: dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain YP_004463182.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: cbi:CLJ_B0872 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inediphosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_004463183.1 KEGG: pfh:PFHG_05237 conserved hypothetical protein; SPTR: FRO1 and FRO2-like protein YP_004463184.1 InterPro IPR019061: IPR014197; KEGG: cdl:CDR20291_0713 hypothetical protein; PFAM: Sporulation protein YunB-like; SPTR: exported protein; TIGRFAM: sporulation protein YunB; PFAM: Sporulation protein YunB (Spo_YunB); TIGRFAM: sporulation protein YunB YP_004463185.1 COGs: COG0162 Tyrosyl-tRNA synthetase; InterPro IPR002305: IPR002942: IPR001412: IPR002307; KEGG: pth:PTH_1020 tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: S4 domain; tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_004463186.1 InterPro IPR000086; KEGG: cce:Ccel_0179 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004463187.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR001498: IPR015269: IPR020569: IPR015796; KEGG: tte:TTE1130 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; Uncharacterised protein family UPF0029, Impact, C-terminal; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family YP_004463188.1 KEGG: mru:mru_1605 hypothetical protein; SPTR: uncharacterized protein YP_004463190.1 InterPro IPR005562: IPR014203; KEGG: cno:NT01CX_1807 stage V sporulation protein AC; PFAM: SpoVA protein; SPTR: Stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC YP_004463191.1 InterPro IPR010894: IPR000209: IPR001412; KEGG: tpd:Teth39_1125 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; SPTR: Stage V sporulation AD family protein; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD YP_004463192.1 InterPro IPR005562: IPR014204; KEGG: aoe:Clos_1789 sporulation stage V protein AE; PFAM: SpoVA protein; SPTR: Sporulation stage V protein AE; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AE YP_004463193.1 COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460: IPR011816; KEGG: tmt:Tmath_0351 penicillin-binding protein, 1A family; PFAM: glycosyl transferase 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family YP_004463194.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: cth:Cthe_0890 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; manually curated; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004463195.1 KEGG: tjr:TherJR_0951 transmembrane anti-sigma factor; SPTR: transmembrane anti-sigma factor YP_004463196.1 COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: amt:Amet_1086 hypothetical protein; PFAM: protein of unknown function DUF541; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF541) YP_004463197.1 InterPro IPR011701; KEGG: tte:TTE1712 major facilitator superfamily permease; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004463198.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterPro IPR020046: IPR020047: IPR001098: IPR019760: IPR 002421: IPR008918: IPR018320: IPR002298; KEGG: cno:NT01CX_1677 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; DNA-directed DNA polymerase; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase A; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; DNA polymerase I YP_004463199.1 COGs: COG0237 Dephospho-CoA kinase; InterPro IPR001977; KEGG: tte:TTE0875 dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; PRIAM: Dephospho-CoA kinase; SPTR: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; manually curated; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase YP_004463200.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258: IPR000189; KEGG: clj:CLJU_c33590 lytic murein transglycosylase; PFAM: Lytic transglycosylase catalytic; SPTR: Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain YP_004463201.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR002328: IPR006140; KEGG: cbt:CLH_2693 sorbitol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Sorbitol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase YP_004463202.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR010559: IPR003594; KEGG: tit:Thit_0427 multi-sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004463203.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR000005: IPR018062: IPR018060: IPR 020449; KEGG: pjd:Pjdr2_5068 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463204.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tmt:Tmath_0508 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463205.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: tit:Thit_0425 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463206.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: tmt:Tmath_0506 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463207.1 COGs: COG4952 sugar isomerase; InterPro IPR012307: IPR013457; KEGG: bld:BLi03559 XylA; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: xylose isomerase; TIGRFAM: L-rhamnose isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: L-rhamnose isomerase, Streptomyces subtype YP_004463208.1 InterPro IPR016007: IPR013737: IPR008902; KEGG: dth:DICTH_0289 alpha-rhamnosidase; PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; SPTR: Alpha-rhamnosidase; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain YP_004463209.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307: IPR011418; KEGG: ttr:Tter_1910 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; AP endonuclease 2 domain protein; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463210.1 KEGG: lga:LGAS_0214 alpha-glucosidase; SPTR: Predicted protein YP_004463211.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: tex:Teth514_1072 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004463212.1 InterPro IPR008902; KEGG: ote:Oter_2903 alpha-L-rhamnosidase; PFAM: alpha-L-rhamnosidase; SPTR: Alpha-L-rhamnosidase; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain YP_004463213.1 InterPro IPR008902; KEGG: sus:Acid_5559 alpha-L-rhamnosidase; PFAM: alpha-L-rhamnosidase; SPTR: Alpha-L-rhamnosidase; PFAM: Bacterial alpha-L-rhamnosidase YP_004463214.1 COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: ttr:Tter_2063 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylation/Crystallin J1; PFAM: ADP-ribosylglycohydrolase YP_004463215.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: tpt:Tpet_1677 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004463216.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: tpt:Tpet_1677 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004463217.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dth:DICTH_1599 oligopeptide ABC transporter, permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide ABC transporter, permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463218.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dth:DICTH_1598 oligopeptide ABC transporter, permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide ABC transporter, permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463219.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439: IPR013563: IPR017871: IPR003593: IPR 010066; KEGG: pjd:Pjdr2_3720 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004463220.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439: IPR013563: IPR017871: IPR003593: IPR 010066; KEGG: dth:DICTH_1596 oligopeptide ABC transporter, ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004463221.1 KEGG: mse:Msed_1731 hypothetical protein; SPTR: Uncharacterized coiled-coil protein-like protein YP_004463222.1 KEGG: dtu:Dtur_0516 hypothetical protein; SPTR: uncharacterized protein YP_004463223.1 InterPro IPR003838; KEGG: pjd:Pjdr2_4257 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004463224.1 InterPro IPR013737: IPR008902; KEGG: ttr:Tter_2039 alpha-L-rhamnosidase; PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; SPTR: Alpha-L-rhamnosidase B; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain YP_004463225.1 KEGG: rba:RB9146 hypothetical protein; SPTR: Alpha-L-rhamnosidase domain protein YP_004463226.1 KEGG: dsy:DSY4756 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463227.1 KEGG: dsy:DSY4756 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463228.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: tpt:Tpet_1687 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004463229.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bbr:BB1788 sulfatase; PFAM: sulfatase; SPTR: sulfatase; PFAM: Sulfatase YP_004463230.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: pjd:Pjdr2_3585 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004463231.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: art:Arth_3955 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463232.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: cma:Cmaq_0237 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase YP_004463233.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: bcv:Bcav_2267 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004463234.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: tpt:Tpet_1677 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Extracellular solute-binding protein, family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004463235.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018062: IPR018060: IPR020449; KEGG: pjd:Pjdr2_3576 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463236.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005: IPR018062: IPR018060; KEGG: pjd:Pjdr2_3016 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain YP_004463237.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485; KEGG: bld:BLi03558 YulC; PFAM: Carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004463238.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: pjd:Pjdr2_4258 efflux transporter, RND family, MFP subunit; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit YP_004463239.1 COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: tte:TTE0993 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase YP_004463240.1 COGs: COG5578 integral membrane protein; InterPro IPR006938; KEGG: tmt:Tmath_0252 protein of unknown function DUF624; PFAM: protein of unknown function DUF624; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF624 YP_004463241.1 COGs: COG1797 Cobyrinic acid a c-diamide synthase; InterPro IPR011698: IPR017929: IPR004484; KEGG: tmt:Tmath_0412 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: Cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase YP_004463242.1 COGs: COG2138 conserved hypothetical protein; InterPro IPR002762; KEGG: tjr:TherJR_1563 cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiX protein; PFAM: CbiX YP_004463243.1 COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tmt:Tmath_0421 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; SPTR: Precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase YP_004463244.1 COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: pth:PTH_0949 ABC-type Co2+ transport system, permease component; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: ABC-type Co2+ transport system, permease component; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM YP_004463245.1 COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: gur:Gura_4180 cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; SPTR: Cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: Cobalt transport protein YP_004463246.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: cpf:CPF_0188 cobalt transporter ATP-binding subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal; TIGRFAM: cobalt transport protein ATP-binding subunit YP_004463247.1 COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR000878: IPR019809: IPR012818; KEGG: lba:Lebu_0508 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit YP_004463248.1 COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR013217: IPR020596: IPR014008; KEGG: tjr:TherJR_1569 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Methyltransferase type 12; SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Methyltransferase small domain; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit YP_004463249.1 COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878: IPR012382: IPR006364; KEGG: drm:Dred_2735 precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase YP_004463250.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878: IPR003043: IPR006362; KEGG: tmt:Tmath_0426 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase YP_004463251.1 COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR002750; KEGG: slp:Slip_0922 cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal YP_004463252.1 COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR006363; KEGG: amt:Amet_0076 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase YP_004463253.1 COGs: COG0373 Glutamyl-tRNA reductase; InterPro IPR015895: IPR006151: IPR015896: IPR000343; KEGG: tit:Thit_0360 glutamyl-tRNA reductase; PFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase-like; Shikimate/quinate 5-dehydrogenase; PRIAM: Glutamyl-tRNA reductase; SPTR: Glutamyl-tRNA reductase; TIGRFAM: glutamyl-tRNA reductase; PFAM: Glutamyl-tRNAGlu reductase, N-terminal domain; Shikimate / quinate 5-dehydrogenase; Glutamyl-tRNAGlu reductase, dimerisation domain; TIGRFAM: glutamyl-tRNA reductase YP_004463254.1 COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: pca:Pcar_3063 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; SPTR: Hydroxymethylbilane synthase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase YP_004463255.1 COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878: IPR003754: IPR003043: IPR006366; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase YP_004463256.1 COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: pth:PTH_0975 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase YP_004463257.1 COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: hmo:HM1_1963 siroheme synthase, N-terminal; SPTR: Siroheme synthase, n-terminal; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain YP_004463258.1 COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814: IPR004639; KEGG: tmt:Tmath_0437 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase YP_004463259.1 COGs: COG2217 Cation transport ATPase; InterPro IPR006121: IPR008250: IPR005834: IPR001757: IPR 001756: IPR001877: IPR018303: IPR017969: IPR006122: IPR006403:I PR006416; KEGG: tte:TTE2463 cation transport ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; copper ion binding protein; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004463260.1 COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537: IPR004657; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_004463261.1 InterPro IPR007730; KEGG: bpd:BURPS668_A2440 sporulation and cell division repeat-containing protein; PFAM: Sporulation domain-containing protein; SPTR: Sporulation domain protein; PFAM: Sporulation related domain YP_004463262.1 KEGG: cpy:Cphy_3800 DRTGG domain-containing protein; SPTR: uncharacterized protein; PFAM: DRTGG domain YP_004463263.1 COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: csc:Csac_1856 anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004463264.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR007202: IPR017900: IPR017896; KEGG: tte:TTE0887 ferredoxin 2; PFAM: Fe-S cluster domain protein; SPTR: Ferredoxin 2; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster YP_004463265.1 KEGG: cth:Cthe_0336 DRTGG domain-containing protein; SPTR: DRTGG domain containing protein; PFAM: DRTGG domain YP_004463266.1 COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: tpd:Teth39_1460 NADH dehydrogenase (ubiquinone), 24 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone) 24 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit YP_004463267.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594: IPR004358: IPR005467; KEGG: amt:Amet_2279 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004463268.1 KEGG: csc:Csac_1862 hypothetical protein; SPTR: uncharacterized protein YP_004463269.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR009737: IPR011538: IPR019554: IPR019575: IPR 017900: IPR001949: IPR017896; KEGG: cth:Cthe_0341 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004463270.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001041: IPR019574: IPR004108: IPR003149: IPR 017900: IPR017896: IPR013352; KEGG: cth:Cthe_0342 hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenases, Fe-only YP_004463271.1 InterPro IPR003115; KEGG: bmq:BMQ_pBM70002 plasmid stability protein; PFAM: ParB domain protein nuclease; SPTR: Chromosome partitioning protein, ParB family; PFAM: ParB-like nuclease domain YP_004463272.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058: IPR020060: IPR001412: IPR004527; KEGG: tex:Teth514_0844 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: Glutamyl-tRNA synthetase; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004463273.1 COGs: COG2323 membrane protein; InterPro IPR007353; KEGG: mta:Moth_0220 hypothetical protein; PFAM: protein of unknown function DUF421; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF421) YP_004463274.1 COGs: COG2608 Copper chaperone; InterPro IPR006121: IPR000428: IPR017969: IPR006122; KEGG: ate:Athe_2279 copper ion binding protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Copper-translocating P-type ATPase; TIGRFAM: copper ion binding protein; PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein YP_004463276.1 COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: hor:Hore_00170 zinc/iron permease; PFAM: zinc/iron permease; SPTR: Zinc/iron permease; PFAM: ZIP Zinc transporter YP_004463277.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: tpd:Teth39_1745 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family YP_004463278.1 COGs: COG1214 Inactive homolog of metal-dependent protease molecular chaperone; InterPro IPR000905; KEGG: cce:Ccel_0800 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease; PFAM: Glycoprotease YP_004463279.1 COGs: COG0456 Acetyltransferase; InterPro IPR000182: IPR006464; KEGG: tte:TTE0537 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferases; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase YP_004463280.1 COGs: COG0533 Metal-dependent protease with possible chaperone activity; InterPro IPR000905: IPR017861; KEGG: cth:Cthe_2743 DNA-binding/iron metalloprotein/AP endonuclease; PFAM: peptidase M22 glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: O-sialoglycoprotein endopeptidase; TIGRFAM: metalloendopeptidase, glycoprotease; PFAM: Glycoprotease; TIGRFAM: glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family YP_004463281.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: cpo:COPRO5265_1581 ABC-type transporter ATP-binding protein EcsA; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type transporter ATP-binding protein EcsA; PFAM: ABC transporter YP_004463282.1 KEGG: cpo:COPRO5265_1580 hypothetical protein; SPTR: uncharacterized protein YP_004463283.1 COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: cbf:CLI_0637 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family YP_004463284.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: clj:CLJU_c25120 ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004463285.1 KEGG: mta:Moth_1173 hypothetical protein; SPTR: uncharacterized protein YP_004463286.1 KEGG: cps:CPS_4697 hypothetical protein; SPTR: uncharacterized protein YP_004463287.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: cac:CA_C0169 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter (ATP-binding protein); PFAM: ABC transporter YP_004463288.1 InterPro IPR013525; KEGG: bcy:Bcer98_0216 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter YP_004463289.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525: IPR016160: IPR000412; KEGG: bcy:Bcer98_0217 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter YP_004463290.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cbf:CLI_0424 DNA-binding response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004463291.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660: IPR003661: IPR003594: IPR004358: IPR 005467; KEGG: cbl:CLK_3541 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004463292.1 KEGG: ctc:CTC01950 hypothetical protein; SPTR: Conserved protein YP_004463293.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: aoe:Clos_2108 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; PFAM: Polysaccharide deacetylase YP_004463294.1 COGs: COG1543 conserved hypothetical protein; InterPro IPR004300: IPR015293; KEGG: tjr:TherJR_0885 domain of unknown function DUF1957; PFAM: Domain of unknown function DUF1957; glycoside hydrolase 57; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase 57 YP_004463295.1 COGs: COG3330 conserved hypothetical protein; KEGG: brm:Bmur_0823 hypothetical protein; SPTR: uncharacterized protein YP_004463296.1 COGs: COG3387 Glucoamylase and related glycosyl hydrolase; InterPro IPR015220: IPR011613: IPR006425; KEGG: tte:TTE1813 hypothetical protein; PFAM: Glucodextranase N; glycoside hydrolase 15-related; PRIAM: Glucan 1,4-alpha-glucosidase; SPTR: uncharacterized protein; TIGRFAM: glucan 1,4-alpha-glucosidase; PFAM: Glucodextranase, domain N; Glycosyl hydrolases family 15; TIGRFAM: glucan 1,4-alpha-glucosidase YP_004463297.1 COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR011108: IPR004613; KEGG: tte:TTE1253 metallo-beta-lactamase superfamily hydrolase; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: Predicted hydrolase of the metallo-beta-lactamase superfamily; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_004463298.1 COGs: COG3679 conserved hypothetical protein; KEGG: sth:STH1710 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF964) YP_004463299.1 COGs: COG4708 membrane protein; InterPro IPR010387; KEGG: tex:Teth514_1496 hypothetical protein; PFAM: protein of unknown function DUF988; SPTR: uncharacterized protein; PFAM: QueT transporter YP_004463300.1 COGs: COG1217 membrane GTPase involved in stress response; InterPro IPR000795: IPR004161: IPR000640: IPR005225: IPR 006298; KEGG: tit:Thit_0818 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_004463301.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); KEGG: slp:Slip_1479 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily YP_004463302.1 COGs: COG2231 Uncharacterized protein related to Endonuclease III; InterPro IPR003265; KEGG: mta:Moth_1560 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004463303.1 COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR019554: IPR000445: IPR003583: IPR004509; KEGG: tpd:Teth39_1421 helix-hairpin-helix repeat-containing competence protein ComEA; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: Helix-hairpin-helix motif; SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein YP_004463304.1 InterPro IPR001387; KEGG: bcu:BCAH820_4414 immunity repressor protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004463305.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_2068 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463306.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2331 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463307.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2464 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463308.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005: IPR020449: IPR018062: IPR018060; KEGG: bmq:BMQ_2170 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463309.1 COGs: COG1874 Beta-galactosidase; InterPro IPR013529: IPR013738: IPR013739: IPR003476; KEGG: bha:BH3701 beta-galactosidase; PFAM: Glycoside hydrolase 42 domain protein; Beta-galactosidase trimerisation domain protein; Beta-galactosidase domain protein; PRIAM: Beta-galactosidase; SPTR: Beta-galactosidase; PFAM: Beta-galactosidase trimerisation domain; Beta-galactosidase C-terminal domain; Beta-galactosidase YP_004463310.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: bbe:BBR47_17160 oxidoreductase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: oxidoreductase; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004463311.1 COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR012307; KEGG: htu:Htur_4472 hydroxypyruvate isomerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Hydroxypyruvate isomerase; SPTR: Hydroxypyruvate isomerase; PFAM: Xylose isomerase-like TIM barrel YP_004463312.1 KEGG: ote:Oter_2886 uroporphyrinogen-III decarboxylase-like protein; SPTR: Uroporphyrinogen-III decarboxylase-like protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463313.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: oih:OB2565 NADH-dependent dyhydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: NADH-dependent dyhydrogenase; PFAM: Oxidoreductase, C-terminal alpha/beta domain; Oxidoreductase, NAD-binding Rossmann fold YP_004463314.1 COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR003142: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; BirA biotin operon repressor domain YP_004463315.1 COGs: COG3191 L-aminopeptidase/D-esterase; InterPro IPR005321; KEGG: cno:NT01CX_1082 T4 family peptidase; PFAM: peptidase S58 DmpA; SPTR: Peptidase T4; PFAM: Peptidase S58 YP_004463316.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140: IPR003439: IPR017871: IPR017940: IPR 003593; KEGG: bha:BH0941 ABC transporter ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter (ATP-binding protein); PFAM: ABC transporter transmembrane region; ABC transporter YP_004463317.1 COGs: COG1576 conserved hypothetical protein; InterPro IPR003742: IPR016051; KEGG: bbe:BBR47_59050 hypothetical protein; PFAM: protein of unknown function DUF163; SPTR: Ribosomal RNA large subunit methyltransferase H; PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH YP_004463318.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941: IPR001091: IPR002052; KEGG: cyn:Cyan7425_0828 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase YP_004463319.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: bcq:BCQ_3004 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004463320.1 COGs: COG0684 Demethylmenaquinone methyltransferase; KEGG: ate:Athe_0205 FldZ protein; SPTR: Demethylmenaquinone methyltransferase-like protein; PFAM: Demethylmenaquinone methyltransferase YP_004463321.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ret:RHE_CH00082 sugar ABC transporter, substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004463322.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: rlg:Rleg_4345 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: transport system permease ABC transporter protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463323.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_0466 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463324.1 InterPro IPR004360; KEGG: lbr:LVIS_2160 lactoylglutathione lyase related lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004463325.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: tmt:Tmath_0177 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004463326.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: tit:Thit_1575 dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthetase; PFAM: Dihydrodipicolinate synthetase YP_004463327.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: tit:Thit_1574 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004463328.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834: IPR005833: IPR006402; KEGG: nwa:Nwat_0747 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase-like hydrolase, ; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004463329.1 COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR013096; KEGG: tit:Thit_1573 cupin 2 conserved barrel domain protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Cupin 2 conserved barrel domain protein; PFAM: Cupin domain YP_004463330.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: tit:Thit_1572 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase YP_004463331.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485: IPR018483: IPR006000; KEGG: tex:Teth514_1911 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase YP_004463332.1 COGs: COG1661 DNA-binding protein with PD1-like DNA-binding motif; InterPro IPR005175; KEGG: ate:Athe_0204 protein of unknown function DUF296; PFAM: protein of unknown function DUF296; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF296) YP_004463333.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: tye:THEYE_A0567 acyl-CoA dehydrogenase, short-chain specific; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase, short-chain specific; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_004463334.1 COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730: IPR012255; KEGG: cce:Ccel_1608 electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: Electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein domain YP_004463335.1 COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730: IPR014731: IPR017900: IPR017896; KEGG: cno:NT01CX_1204 electron transfer flavoprotein, alpha subunit; PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; SPTR: Electron transfer flavoprotein, alpha subunit; PFAM: 4Fe-4S binding domain; Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain YP_004463336.1 COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR001959: IPR010095; KEGG: mfs:MFS40622_1028 transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; transposase IS891/IS1136/IS1341 family; SPTR: Transposase, IS605 OrfB family, central region; TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region YP_004463337.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR000005: IPR020449: IPR018060; KEGG: csc:Csac_2550 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463338.1 KEGG: csc:Csac_2551 integral membrane sensor signal transduction histidine kinase; SPTR: Integral membrane sensor signal transduction histidine kinase YP_004463339.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003660: IPR010559: IPR003594; KEGG: csc:Csac_2551 integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004463340.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: csc:Csac_2554 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463341.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ate:Athe_0086 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463342.1 InterPro IPR006059; KEGG: gym:GYMC10_0541 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463344.1 KEGG: bll:BLJ_1916 beta-agarase; PRIAM: Beta-agarase; SPTR: Beta-agarase YP_004463345.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104: IPR006102: IPR006103: IPR004199: IPR 006101; KEGG: bbe:BBR47_58080 probable beta-galactosidase; PFAM: glycoside hydrolase 2 TIM barrel; glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 42 domain 5 loop region; PRIAM: Beta-galactosidase; SPTR: Probable beta-galactosidase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; Beta galactosidase small chain YP_004463346.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005: IPR020449: IPR018060; KEGG: pjd:Pjdr2_4157 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463347.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_4133 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463348.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cpy:Cphy_0930 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463349.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_4183 ABC-type sugar transport system periplasmic component-like protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transport system periplasmic component-like protein; PFAM: Bacterial extracellular solute-binding protein YP_004463350.1 InterPro IPR003961: IPR006626; KEGG: msl:Msil_2809 hypothetical protein; PFAM: Fibronectin type III domain protein; SPTR: uncharacterized protein YP_004463351.1 KEGG: rca:Rcas_2444 hypothetical protein; SPTR: uncharacterized protein YP_004463352.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR004184: IPR001150; KEGG: tko:TK0289 pyruvate-formate lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; SPTR: uncharacterized protein; PFAM: Glycine radical; Pyruvate formate lyase YP_004463353.1 COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: aac:Aaci_2531 transcriptional regulator, IclR family; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Transcriptional regulator, IclR family; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_004463354.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197: IPR011352: IPR017900: IPR001989: IPR 017896: IPR012839; KEGG: tko:TK0290 pyruvate-formate lyase-activating enzyme; PFAM: Radical SAM domain protein; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: Glycyl-radical enzyme activating protein family; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: 4Fe-4S binding domain; Radical SAM superfamily; TIGRFAM: glycyl-radical enzyme activating protein family YP_004463355.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: caa:Caka_0351 uroporphyrinogen-III decarboxylase-like protein; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463356.1 KEGG: caa:Caka_0351 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463357.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: sus:Acid_3906 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase, ; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004463358.1 COGs: COG1514 2'-5' RNA ligase; InterPro IPR014051: IPR004175; KEGG: cth:Cthe_0503 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; SPTR: 2'-5' RNA ligase; TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase; TIGRFAM: 2'-5' RNA ligase YP_004463359.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608: IPR011078; KEGG: cth:Cthe_0792 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: uncharacterized protein; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_004463360.1 COGs: COG1799 conserved hypothetical protein; InterPro IPR007561; KEGG: dhd:Dhaf_4046 protein of unknown function DUF552; PFAM: protein of unknown function DUF552; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF552) YP_004463361.1 InterPro IPR003425; KEGG: mta:Moth_0861 hypothetical protein; PFAM: protein of unknown function YGGT; SPTR: uncharacterized protein; PFAM: YGGT family YP_004463362.1 COGs: COG3599 Cell division initiation protein; InterPro IPR007793: IPR019933; KEGG: aoe:Clos_1411 DivIVA family protein; PFAM: DivIVA family protein; SPTR: DivIVA family protein; TIGRFAM: DivIVA domain; manually curated; PFAM: DivIVA protein; TIGRFAM: DivIVA domain YP_004463363.1 COGs: COG0060 Isoleucyl-tRNA synthetase; InterPro IPR002300: IPR013155: IPR010663: IPR015905: IPR 001412: IPR002301; KEGG: cth:Cthe_0787 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Zinc finger found in FPG and IleRS; TIGRFAM: isoleucyl-tRNA synthetase YP_004463364.1 COGs: COG1796 DNA polymerase IV (family X); InterPro IPR004013: IPR002008: IPR002054: IPR003583: IPR 003141; KEGG: tte:TTE2516 family X DNA polymerase IV; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein; SPTR: DNA polymerase IV (Family X); manually curated; PFAM: PHP domain YP_004463365.1 COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR018164: IPR012947: IPR003156: IPR018165: IPR 002318; KEGG: cth:Cthe_3200 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc-like; Threonyl/alanyl tRNA synthetase SAD; phosphoesterase DHHA1; SPTR: Alanyl-tRNA synthetase; TIGRFAM: alanyl-tRNA synthetase; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase YP_004463366.1 COGs: COG1578 conserved hypothetical protein; InterPro IPR002791: IPR014444; KEGG: tjr:TherJR_1354 protein of unknown function DUF89; PFAM: protein of unknown function DUF89; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF89 YP_004463367.1 KEGG: chy:CHY_0834 hypothetical protein; SPTR: uncharacterized protein YP_004463368.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218: IPR006268; KEGG: cth:Cthe_0880 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase YP_004463369.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: amt:Amet_2452 BadM/Rrf2 family transcriptional regulator; PFAM: protein of unknown function UPF0074; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein ( transcriptional regulator) YP_004463370.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR010240: IPR016454: IPR020578: IPR 017772; KEGG: mpl:Mpal_1837 cysteine desulfurase NifS; PFAM: aminotransferase class V; SPTR: Cysteine desulfurase NifS; TIGRFAM: cysteine desulfurase NifS; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase NifS YP_004463371.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871: IPR017787; KEGG: chy:CHY_2198 FeS assembly protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: FeS assembly protein; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: NifU-like N terminal domain; TIGRFAM: FeS cluster assembly scaffold IscU; FeS cluster assembly scaffold protein NifU, Clostridium type YP_004463372.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: tpd:Teth39_0281 tRNA-specific 2-thiouridylase MnmA; SPTR: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004463373.1 COGs: COG0782 Transcription elongation factor; InterPro IPR001437: IPR018151; KEGG: slp:Slip_1131 GreA/GreB family elongation factor; PFAM: transcription elongation factor GreA/GreB domain-containing protein; SPTR: GreA/GreB family elongation factor; PFAM: Transcription elongation factor, GreA/GreB, C-term YP_004463374.1 KEGG: pjd:Pjdr2_4182 binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004463375.1 KEGG: gwc:GWCH70_3369 hypothetical protein; SPTR: uncharacterized protein YP_004463376.1 KEGG: tmt:Tmath_0929 hypothetical protein; SPTR: uncharacterized protein YP_004463377.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: tjr:TherJR_2108 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1 YP_004463378.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004010: IPR003660: IPR004089; KEGG: csc:Csac_2452 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis sensory transducer; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004463379.1 InterPro IPR013216; KEGG: lla:L28696 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 12; PFAM: Methyltransferase domain YP_004463380.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: cth:Cthe_2578 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: Ppx/GppA phosphatase; PFAM: HD domain; Ppx/GppA phosphatase; TIGRFAM: exopolyphosphatase YP_004463381.1 COGs: COG0125 Thymidylate kinase; InterPro IPR000062: IPR018094; KEGG: gur:Gura_2566 dTMP kinase; PFAM: thymidylate kinase; SPTR: Thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_004463382.1 COGs: COG0125 Thymidylate kinase; InterPro IPR000062: IPR018094; KEGG: gur:Gura_2642 thymidylate kinase; PFAM: thymidylate kinase; SPTR: Thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_004463383.1 COGs: COG0474 Cation transport ATPase; InterPro IPR004014: IPR008250: IPR005834: IPR006068: IPR 001757: IPR000695: IPR018303: IPR006408; KEGG: tte:TTE0030 cation transport ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: calcium-translocating P-type ATPase, PMCA-type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; potassium and/or sodium efflux P-type ATPase, fungal-type YP_004463384.1 KEGG: nth:Nther_0553 hypothetical protein; SPTR: uncharacterized protein YP_004463385.1 COGs: COG1109 Phosphomannomutase; InterPro IPR005844: IPR005845: IPR005846: IPR005843: IPR 005841: IPR016066; KEGG: tpd:Teth39_1557 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004463386.1 COGs: COG4464 Capsular polysaccharide biosynthesis protein; InterPro IPR004013: IPR016667; KEGG: llk:LLKF_0134 protein-tyrosine-phosphatase; PFAM: PHP domain protein; PRIAM: Protein-tyrosine-phosphatase; SPTR: EpsC YP_004463387.1 KEGG: tmt:Tmath_0712 hypothetical protein; SPTR: uncharacterized protein; PFAM: transposase, YhgA-like YP_004463388.1 InterPro IPR018631: IPR012547; KEGG: cbt:CLH_3192 hypothetical protein; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase YP_004463389.1 InterPro IPR012912; KEGG: tte:TTE0676 hypothetical protein; PFAM: plasmid pRiA4b ORF-3 family protein; SPTR: uncharacterized protein; PFAM: Plasmid pRiA4b ORF-3-like protein YP_004463390.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: csc:Csac_0350 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463391.1 COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: mta:Moth_1954 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004463392.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: ate:Athe_2390 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004463393.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485: IPR018483; KEGG: csc:Csac_0348 carbohydrate kinase, FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Carbohydrate kinase, FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004463394.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR002347: IPR020904; KEGG: cpo:COPRO5265_1582 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-(Acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase YP_004463395.1 COGs: COG2344 AT-rich DNA-binding protein; InterPro IPR009718: IPR003781; KEGG: cdl:CDR20291_0171 redox-sensing transcriptional repressor REX; PFAM: CoA-binding domain protein; Rex DNA-binding domain protein; SPTR: uncharacterized protein; PFAM: CoA binding domain; DNA-binding protein N-terminus YP_004463396.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001041: IPR019574: IPR004108: IPR003149: IPR 017900: IPR000283: IPR017896: IPR013352; KEGG: mta:Moth_1717 iron hydrogenase, small subunit; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Iron hydrogenase, small subunit; TIGRFAM: hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenases, Fe-only YP_004463397.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538: IPR019554: IPR019575: IPR001949; KEGG: tnp:Tnap_0858 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADP-reducing hydrogenase, subunit C; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004463398.1 COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: dth:DICTH_1579 NADH-quinone oxidoreductase chain E; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: [Fe] hydrogenase (Fe-only hydrogenase) (Ferredoxin bidirectional hydrogenase), subunit gamma (HymA-like); PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit YP_004463399.1 COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR007202: IPR002078: IPR002197: IPR017900: IPR 017896: IPR003593; KEGG: hor:Hore_02950 PAS/PAC sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; Fe-S cluster domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: PAS/PAC sensor protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster; Sigma-54 interaction domain; TIGRFAM: PAS domain S-box YP_004463400.1 InterPro IPR001584; KEGG: tjr:TherJR_2621 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004463401.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277: IPR006235; KEGG: cth:Cthe_1842 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_004463402.1 COGs: COG2021 Homoserine acetyltransferase; InterPro IPR000073: IPR008220: IPR006296; KEGG: csc:Csac_1575 homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; PRIAM: Homoserine O-acetyltransferase; SPTR: Homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase YP_004463403.1 COGs: COG4100 Cystathionine beta-lyase involved in aluminum resistance; InterPro IPR009651; KEGG: clj:CLJU_c21200 aluminum resistance protein; PFAM: Aluminium resistance family protein; SPTR: Aluminium resistance family protein; PFAM: Aluminium resistance protein YP_004463404.1 COGs: COG3350 conserved hypothetical protein; InterPro IPR007029: IPR011017; KEGG: dtu:Dtur_1579 YHS domain protein; PFAM: YHS domain-containing protein; SMART: TRASH domain-containing protein; SPTR: YHS domain protein; PFAM: YHS domain YP_004463405.1 COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959: IPR000641: IPR003593; KEGG: tmt:Tmath_1212 stage V sporulation protein K; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; PFAM: ATPase associated with various cellular activities (AAA); TIGRFAM: stage V sporulation protein K YP_004463406.1 COGs: COG0486 GTPase; InterPro IPR002917; KEGG: amt:Amet_2539 GTP-binding protein, HSR1-related; PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein, HSR1-related; PFAM: GTPase of unknown function YP_004463407.1 KEGG: cbf:CLI_1017 hypothetical protein; SPTR: uncharacterized protein YP_004463408.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR006199: IPR019759: IPR006200: IPR006197; KEGG: aoe:Clos_1549 LexA repressor; PFAM: LexA DNA-binding domain protein; Peptidase S24/S26A/S26B, conserved region; SPTR: LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA binding domain; Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_004463409.1 InterPro IPR018392: IPR002482; KEGG: hor:Hore_11460 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; PFAM: LysM domain YP_004463410.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: cth:Cthe_0728 site-specific tyrosine recombinase XerC; PFAM: integrase; integrase domain protein SAM domain protein; SPTR: Phage integrase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase YP_004463411.1 COGs: COG0328 Ribonuclease HI; InterPro IPR002156; KEGG: tjr:TherJR_1738 ribonuclease H; PFAM: ribonuclease H; PRIAM: Ribonuclease H; SPTR: Ribonuclease H; PFAM: RNase H YP_004463412.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455: IPR000304: IPR017441; KEGG: ctc:CTC02431 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_004463413.1 COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR008279: IPR018209: IPR 001697; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase YP_004463414.1 COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: tte:TTE0370 ATP:corrinoid adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; SPTR: ATP:corrinoid adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase YP_004463415.1 InterPro IPR008844; KEGG: amt:Amet_0872 spore germination B3 GerAC family protein; PFAM: spore germination B3 GerAC family protein; SPTR: Spore germination B3 GerAC family protein; TIGRFAM: germination protein, Ger(x)C family; PFAM: Spore germination B3/ GerAC like, C-terminal; TIGRFAM: germination protein, Ger(x)C family YP_004463416.1 InterPro IPR004761; KEGG: amt:Amet_0513 spore germination protein; PFAM: Spore germination protein; SPTR: Spore germination protein; TIGRFAM: spore germination protein; PFAM: Spore germination protein; TIGRFAM: spore germination protein (amino acid permease) YP_004463417.1 InterPro IPR004995; KEGG: amt:Amet_0870 GerA spore germination protein; PFAM: GerA spore germination protein; SPTR: GerA spore germination protein; PFAM: Bacillus/Clostridium GerA spore germination protein YP_004463418.1 COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR004792: IPR003042: IPR000102: IPR011777; KEGG: mev:Metev_1700 geranylgeranyl reductase; PFAM: HI0933 family protein; SPTR: Geranylgeranyl reductase; TIGRFAM: geranylgeranyl reductase; PFAM: FAD binding domain; TIGRFAM: geranylgeranyl reductase YP_004463419.1 KEGG: tjr:TherJR_2939 hypothetical protein; SPTR: uncharacterized protein; PFAM: Ferritin-like domain YP_004463420.1 COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: dae:Dtox_0718 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1015) YP_004463421.1 KEGG: sti:Sthe_1313 hypothetical protein; SPTR: uncharacterized protein YP_004463422.1 KEGG: ate:Athe_1278 hypothetical protein; SPTR: uncharacterized protein YP_004463423.1 InterPro IPR000551; KEGG: aoe:Clos_1556 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Transcriptional regulator, MerR family; PFAM: MerR family regulatory protein YP_004463424.1 COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: cth:Cthe_0611 RNA-metabolising metallo-beta-lactamase; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: RNA-metabolising metallo-beta-lactamase; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain YP_004463425.1 COGs: COG2206 HD-GYP domain; InterPro IPR006674: IPR003607; KEGG: tjr:TherJR_0746 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004463426.1 COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933: IPR011650: IPR017439: IPR010168; KEGG: amt:Amet_1622 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: amidohydrolase; PFAM: Peptidase M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase YP_004463427.1 COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: tit:Thit_0529 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase YP_004463428.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: drm:Dred_1836 ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, periplasmic component; SPTR: ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, periplasmic component; PFAM: NMT1/THI5 like YP_004463429.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: tpd:Teth39_1644 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004463430.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: drm:Dred_1834 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463431.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cpy:Cphy_1177 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004463432.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034: IPR014036: IPR018356: IPR001845; KEGG: csc:Csac_0990 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004463433.1 COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR000836: IPR006273; KEGG: aoe:Clos_2190 orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: orotate phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase, Thermus family; orotate phosphoribosyltransferase YP_004463434.1 COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135: IPR001295: IPR005720; KEGG: cth:Cthe_0947 dihydroorotate oxidase B, catalytic subunit; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate oxidase B, catalytic subunit; TIGRFAM: dihydroorotate dehydrogenase; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein YP_004463435.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433: IPR019480: IPR012165: IPR017927; KEGG: cth:Cthe_0948 dihydroorotate oxidase B, electron transfer subunit; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004463436.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481: IPR005479: IPR005480: IPR011607: IPR 005483: IPR011761: IPR006275; KEGG: cth:Cthe_0949 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoyl-phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004463437.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR001754: IPR018089: IPR011995; KEGG: cth:Cthe_0951 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2 YP_004463438.1 COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680: IPR002195: IPR004722; KEGG: cth:Cthe_0952 dihydroorotase; PFAM: amidohydrolase; PRIAM: Dihydroorotase; SPTR: Dihydroorotase; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase; TIGRFAM: dihydroorotase, multifunctional complex type YP_004463439.1 COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006132: IPR006131: IPR002082: IPR006130; KEGG: cce:Ccel_0612 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; aspartate carbamoyltransferase YP_004463440.1 COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: hor:Hore_09350 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain YP_004463441.1 COGs: COG1814 Uncharacterized membrane protein; InterPro IPR008217; KEGG: tpd:Teth39_1872 hypothetical protein; PFAM: protein of unknown function DUF125 transmembrane; SPTR: uncharacterized protein; PFAM: Rubrerythrin; VIT family YP_004463442.1 COGs: COG1247 Sortase and related acyltransferase; InterPro IPR000182; KEGG: bbe:BBR47_09020 phosphinothricin acetyltransferase; PFAM: GCN5-related N-acetyltransferase; PRIAM: Phosphinothricin acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004463443.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cpo:COPRO5265_0068 Na+-driven multidrug efflux pump; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Na+-driven multidrug efflux pump; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004463444.1 COGs: COG0014 Gamma-glutamyl phosphate reductase; InterPro IPR015590: IPR012134: IPR000965; KEGG: cbt:CLH_0047 gamma-glutamyl phosphate reductase; PFAM: Aldehyde Dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase; PFAM: Aldehyde dehydrogenase; TIGRFAM: gamma-glutamyl phosphate reductase YP_004463445.1 COGs: COG0263 Glutamate 5-kinase; InterPro IPR001048: IPR001057: IPR011529: IPR019797: IPR 005715; KEGG: ate:Athe_1645 glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: Amino acid kinase; TIGRFAM: glutamate 5-kinase YP_004463446.1 COGs: COG1569 nucleic acid-binding protein contains PIN domain; InterPro IPR002716: IPR006596: IPR002850; KEGG: tit:Thit_2260 PilT protein domain protein; PFAM: PilT protein domain protein; SMART: Nucleotide binding protein PINc; SPTR: PilT protein domain protein; PFAM: PIN domain; TIGRFAM: probable toxin-antitoxin system toxin component, PIN family YP_004463447.1 InterPro IPR006442; KEGG: tmt:Tmath_2167 prevent-host-death family protein; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004463448.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: dsy:DSY2147 hypothetical protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004463449.1 KEGG: dsy:DSY2148 hypothetical protein; SPTR: uncharacterized protein YP_004463450.1 KEGG: cth:Cthe_2986 hypothetical protein; SPTR: uncharacterized protein YP_004463451.1 KEGG: cth:Cthe_2988 hypothetical protein; SPTR: uncharacterized protein YP_004463452.1 KEGG: apr:Apre_1527 hypothetical protein; SPTR: uncharacterized protein YP_004463453.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: dsy:DSY2147 hypothetical protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004463454.1 KEGG: cth:Cthe_2985 hypothetical protein; SPTR: uncharacterized protein YP_004463455.1 KEGG: cth:Cthe_2986 hypothetical protein; SPTR: uncharacterized protein YP_004463456.1 KEGG: cth:Cthe_2988 hypothetical protein; SPTR: uncharacterized protein YP_004463457.1 COGs: COG3874 conserved hypothetical protein; InterPro IPR014229: IPR017975; KEGG: tjr:TherJR_1631 sporulation protein YtfJ; PFAM: Sporulation protein YtfJ; SPTR: Sporulation protein YtfJ; TIGRFAM: sporulation protein YtfJ; PFAM: Sporulation protein YtfJ (Spore_YtfJ); TIGRFAM: sporulation protein YtfJ YP_004463458.1 KEGG: tjr:TherJR_1632 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2953) YP_004463459.1 COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: cbe:Cbei_1876 segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; SPTR: uncharacterized protein; TIGRFAM: segregation and condensation protein B; PFAM: transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B YP_004463460.1 COGs: COG1354 conserved hypothetical protein; InterPro IPR003768; KEGG: bts:Btus_1821 chromosome segregation and condensation protein ScpA; PFAM: chromosome segregation and condensation protein ScpA; SPTR: Segregation and condensation protein A; PFAM: ScpA/B protein YP_004463461.1 COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002305: IPR002306: IPR001412; KEGG: cth:Cthe_0686 tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_004463462.1 COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: tit:Thit_1118 peptidase M50; PFAM: peptidase M50; SPTR: Peptidase M50; PFAM: Peptidase M50 YP_004463463.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183: IPR002986; KEGG: slp:Slip_0535 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Diaminopimelate decarboxylase; TIGRFAM: diaminopimelate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_004463464.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967: IPR012907: IPR018044; KEGG: ate:Athe_1559 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain YP_004463465.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845: IPR011268: IPR011270; KEGG: hor:Hore_06960 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: purine or other phosphorylase 1; SPTR: Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: inosine guanosine and xanthosine phosphorylase; purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: Phosphorylase superfamily; TIGRFAM: purine nucleoside phosphorylase I, inosine and guanosine-specific; inosine guanosine and xanthosine phosphorylase YP_004463466.1 COGs: COG1015 Phosphopentomutase; InterPro IPR006124: IPR010045; KEGG: cth:Cthe_0677 phosphopentomutase; PFAM: metalloenzyme domain protein; PRIAM: Phosphopentomutase; SPTR: Phosphopentomutase; TIGRFAM: phosphopentomutase; PFAM: Metalloenzyme superfamily; TIGRFAM: phosphopentomutase YP_004463467.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: tjr:TherJR_1666 tyrosine recombinase XerD; PFAM: integrase; integrase domain protein SAM domain protein; SPTR: Tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase YP_004463468.1 InterPro IPR002798: IPR014196; KEGG: amt:Amet_2522 sporulation stage II, protein M; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Stage II sporulation protein M; TIGRFAM: stage II sporulation protein M; PFAM: Integral membrane protein DUF95; TIGRFAM: stage II sporulation protein M YP_004463469.1 InterPro IPR000086: IPR020084; KEGG: tpd:Teth39_1115 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004463470.1 KEGG: amt:Amet_2520 hypothetical protein; SPTR: uncharacterized protein YP_004463471.1 KEGG: cdl:CDR20291_1056 glycosyltransferase; SPTR: glycosyltransferase; PFAM: Glycosyl transferase 4 YP_004463472.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: tte:TTE1307 cell wall biosynthesis glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: Glycosyltransferases involved in cell wall biogenesis; PFAM: Glycosyl transferase 2 YP_004463473.1 KEGG: tte:TTE1306 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3186) YP_004463474.1 COGs: COG4825 Uncharacterized membrane-anchored protein; InterPro IPR007371; KEGG: tte:TTE1305 hypothetical protein; PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; SPTR: uncharacterized protein; PFAM: Thiamine pyrophosphokinase C terminal YP_004463475.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR014879: IPR012052; KEGG: cdl:CDR20291_1052 stage 0 sporulation protein A; PFAM: Sporulation initiation factor Spo0A; response regulator receiver; SMART: response regulator receiver; SPTR: Stage 0 sporulation protein A; TIGRFAM: sporulation transcription factor Spo0A; PFAM: Sporulation initiation factor Spo0A C terminal; Response regulator receiver domain; TIGRFAM: sporulation transcription factor Spo0A YP_004463476.1 COGs: COG1521 transcriptional regulator protein; InterPro IPR004619; KEGG: cth:Cthe_2588 pantothenate kinase; PFAM: Bvg accessory factor; PRIAM: Pantothenate kinase; SPTR: transcriptional acitvator, Baf family; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III YP_004463477.1 COGs: COG4684 membrane protein; KEGG: pmo:Pmob_0245 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004463478.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197: IPR006638; KEGG: ate:Athe_2185 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004463479.1 KEGG: dau:Daud_1724 hypothetical protein; SPTR: uncharacterized protein YP_004463480.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258: IPR000189; KEGG: cce:Ccel_0815 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; SPTR: Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain YP_004463481.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200: IPR000150: IPR006379; KEGG: aoe:Clos_0919 Cof-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: Cof-like hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004463482.1 COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR003714: IPR006596; KEGG: dal:Dalk_3397 PhoH family protein; PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; SPTR: PhoH family protein; PFAM: PhoH-like protein YP_004463483.1 COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000644: IPR000160; KEGG: cbe:Cbei_3303 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004463484.1 COGs: COG1939 conserved hypothetical protein; InterPro IPR000999: IPR008226; KEGG: cth:Cthe_2061 hypothetical protein; PFAM: ribonuclease III; SMART: ribonuclease III; SPTR: uncharacterized protein; PFAM: RNase3 domain YP_004463485.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803: IPR015273: IPR002308; KEGG: cth:Cthe_2065 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase YP_004463486.1 COGs: COG1045 Serine acetyltransferase; InterPro IPR001451: IPR005881; KEGG: aoe:Clos_0468 serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase YP_004463487.1 KEGG: ptm:GSPATT00002716001 hypothetical protein; SPTR: Phosphatidylserine synthase YP_004463488.1 KEGG: csc:Csac_1120 hypothetical protein; SPTR: uncharacterized protein YP_004463489.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508: IPR014234; KEGG: tmt:Tmath_1888 N-acetylmuramoyl-L-alanine amidase CwlD; PFAM: cell wall hydrolase/autolysin; PRIAM: N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase CwlD; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD; PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD YP_004463490.1 COGs: COG0148 Enolase; InterPro IPR020811: IPR020810: IPR000941: IPR020809; KEGG: tmt:Tmath_1558 enolase; PFAM: Enolase-like; PRIAM: Phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: enolase; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004463491.1 COGs: COG0696 Phosphoglyceromutase; InterPro IPR011258: IPR006124: IPR005995; KEGG: ate:Athe_1404 phosphoglyceromutase; PFAM: BPG-independent PGAM domain protein; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase YP_004463492.1 COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652: IPR020861; KEGG: tte:TTE1760 triosephosphate isomerase; PFAM: triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_004463493.1 COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576: IPR015911; KEGG: tte:TTE1761 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase YP_004463494.1 COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828: IPR020829: IPR020832: IPR020831: IPR 020830: IPR006424; KEGG: csc:Csac_1953 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_004463495.1 COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: pth:PTH_2724 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor YP_004463496.1 InterPro IPR000424; KEGG: cpf:CPF_2166 single-stranded DNA-binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Probable single stranded binding protein; PFAM: Single-strand binding protein family YP_004463497.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: aoe:Clos_2018 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; TIGRFAM: polysaccharide deacetylase sporulation protein PdaB YP_004463498.1 KEGG: der:Dere_GG14128 GG14128 gene product from transcript GG14128-RA; SPTR: uncharacterized protein YP_004463499.1 KEGG: gtn:GTNG_2071 transposase; SPTR: Zinc finger C2H2-type domain protein YP_004463500.1 COGs: COG0004 Ammonia permease; InterPro IPR001905: IPR018047; KEGG: csc:Csac_2477 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter YP_004463501.1 COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187: IPR017918; KEGG: csc:Csac_2476 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein P-II YP_004463502.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: csc:Csac_0599 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004463503.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: csc:Csac_0598 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463504.1 KEGG: mru:mru_1131 hypothetical protein; SPTR: uncharacterized protein YP_004463505.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254: IPR001478: IPR001940; KEGG: ctc:CTC00192 periplasmic trypsin-like serine protease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: Periplasmic trypsin-like serine protease; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF) YP_004463506.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660: IPR003661: IPR003594: IPR004358: IPR 005467; KEGG: tpd:Teth39_0165 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004463507.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cth:Cthe_1288 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004463508.1 COGs: COG4866 conserved hypothetical protein; InterPro IPR016732; KEGG: afn:Acfer_0904 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2156) YP_004463509.1 KEGG: cth:Cthe_0434 ATPase; SPTR: ATPase YP_004463510.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR004101: IPR018109: IPR001645; KEGG: aoe:Clos_2028 FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; SPTR: FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004463511.1 KEGG: tmt:Tmath_2131 molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; PFAM: Uncharacterized protein family UPF0007 YP_004463512.1 COGs: COG3030 Protein affecting phage T7 exclusion by the F plasmid; InterPro IPR007313; KEGG: bcg:BCG9842_B0530 FxsA; PFAM: FxsA cytoplasmic membrane protein; SPTR: FxsA cytoplasmic membrane protein; PFAM: FxsA cytoplasmic membrane protein YP_004463513.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789: IPR002078: IPR002197: IPR020441: IPR 003593; KEGG: drm:Dred_1510 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004463514.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660: IPR003661: IPR003594: IPR004358: IPR 005467; KEGG: drm:Dred_2000 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004463515.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: tjr:TherJR_2632 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004463516.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: ate:Athe_1574 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004463517.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: tjr:TherJR_2634 efflux transporter, RND family, MFP subunit; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit YP_004463518.1 COGs: COG4641 conserved hypothetical protein; KEGG: dae:Dtox_1137 hypothetical protein; SPTR: uncharacterized protein YP_004463519.1 COGs: COG2327 conserved hypothetical protein; KEGG: cth:Cthe_2702 polysaccharide pyruvyl transferase; SPTR: Polysaccharide pyruvyl transferase; PFAM: Polysaccharide pyruvyl transferase YP_004463520.1 COGs: COG0785 Cytochrome c biogenesis protein; InterPro IPR003834; KEGG: cce:Ccel_1660 cytochrome c biogenesis protein transmembrane region; PFAM: cytochrome c biogenesis protein transmembrane region; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region YP_004463521.1 COGs: COG1225 Peroxiredoxin; InterPro IPR000866: IPR017937: IPR017936; KEGG: cdl:CDR20291_2846 cytochrome c biogenesis protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: AhpC/TSA; PFAM: AhpC/TSA family YP_004463522.1 COGs: COG0536 GTPase; InterPro IPR006169: IPR002917: IPR015349: IPR006073: IPR 014100: IPR006074; KEGG: ate:Athe_1121 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; GTP1/OBG domain protein; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; Obg family GTPase CgtA; PFAM: GTPase of unknown function; Domain of unknown function (DUF1967); GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; Obg family GTPase CgtA, C-terminal extension; small GTP-binding protein domain YP_004463523.1 COGs: COG0211 Ribosomal protein L27; InterPro IPR001684: IPR018261; KEGG: cpy:Cphy_2549 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: LSU ribosomal protein L27P; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_004463524.1 COGs: COG2868 ribosomal protein; InterPro IPR007422; KEGG: slp:Slip_0706 protein of unknown function DUF464; PFAM: protein of unknown function DUF464; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF464) YP_004463525.1 COGs: COG0261 Ribosomal protein L21; InterPro IPR001787: IPR018258; KEGG: cth:Cthe_0160 50S ribosomal protein L21; PFAM: ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: ribosomal protein L21; PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_004463526.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646: IPR006674: IPR006675; KEGG: sun:SUN_0962 polynucleotide adenylyltransferase/metal-dependent phosphohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Polynucleotide adenylyltransferase/metal-dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: uncharacterized domain HDIG YP_004463527.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: phe:Phep_2596 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein YP_004463528.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197: IPR016431; KEGG: tte:TTE1955 pyruvate-formate lyase-activating enzyme; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004463529.1 COGs: COG3885 conserved hypothetical protein; InterPro IPR004183: IPR002733; KEGG: tpd:Teth39_0581 hypothetical protein; PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; PFAM: AMMECR1; Catalytic LigB subunit of aromatic ring-opening dioxygenase; TIGRFAM: uncharacterized protein, PH0010 family YP_004463530.1 COGs: COG0054 Riboflavin synthase beta-chain; InterPro IPR002180; KEGG: cac:CA_C0593 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_004463531.1 COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; InterPro IPR000422: IPR000926: IPR016299: IPR010916; KEGG: tjr:TherJR_1781 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; SPTR: 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004463532.1 COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cno:NT01CX_0714 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit YP_004463533.1 COGs: COG0117 Pyrimidine deaminase; InterPro IPR002125: IPR002734: IPR016192: IPR004794: IPR 011549; KEGG: amt:Amet_1018 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD YP_004463534.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR001228: IPR003526: IPR018294: IPR020555; KEGG: dau:Daud_0186 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: MECDP-synthase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: YgbB family; Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004463535.1 COGs: COG4166 ABC-type oligopeptide transport system periplasmic component; InterPro IPR000914; KEGG: tte:TTE0609 ABC-type dipeptide/oligopeptide/nickel transport systems, periplasmic components; PFAM: extracellular solute-binding protein family 5; SPTR: 4-phytase; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004463536.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: tpd:Teth39_1688 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463537.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: tte:TTE0613 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463538.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439: IPR013563: IPR017871: IPR003593: IPR 010066; KEGG: tpd:Teth39_1686 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004463539.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439: IPR013563: IPR017871: IPR003593: IPR 010066; KEGG: tte:TTE0615 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004463540.1 InterPro IPR017900: IPR017896; KEGG: mmq:MmarC5_1578 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain YP_004463541.1 COGs: COG0390 ABC-type uncharacterized transport system permease component; InterPro IPR005226; KEGG: amt:Amet_1586 hypothetical protein; PFAM: Conserved hypothetical protein CHP00245; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0014); TIGRFAM: conserved hypothetical protein TIGR00245 YP_004463542.1 COGs: COG4988 ABC-type transport system involved in cytochrome bd biosynthesis ATPase and permease components; InterPro IPR003439: IPR017871: IPR003593; KEGG: amt:Amet_1587 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Phosphate ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004463543.1 COGs: COG0412 Dienelactone hydrolase; KEGG: tit:Thit_1725 acetyl xylan esterase; SPTR: Acetyl xylan esterase; PFAM: Acetyl xylan esterase (AXE1) YP_004463544.1 KEGG: bvu:BVU_2930 trimethylamine corrinoid protein 2; SPTR: B12 binding domain./Pterin binding enzyme YP_004463545.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: cpo:COPRO5265_0115 beta-N-acetylglucosaminidase; PFAM: glycoside hydrolase 3 domain protein; SPTR: Beta-N-Acetylglucosaminidase; PFAM: Glycosyl hydrolase 3 N terminal domain YP_004463546.1 COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR000005: IPR020449: IPR018062: IPR018060; KEGG: ect:ECIAI39_4283 DNA-binding transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: DNA-binding transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463547.1 KEGG: caa:Caka_0351 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463548.1 SPTR: uncharacterized protein YP_004463549.1 InterPro IPR010178; KEGG: amt:Amet_3274 hypothetical protein; PFAM: Integral membrane protein 1906; SPTR: Integral membrane protein TIGR01906; TIGRFAM: integral membrane protein TIGR01906; PFAM: Protein of unknown function (DUF1461); TIGRFAM: integral membrane protein TIGR01906 YP_004463550.1 InterPro IPR002035; KEGG: swo:Swol_1716 chloride channel; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Conserved chloride channel; PFAM: von Willebrand factor type A domain; Protein of unknown function (DUF1355) YP_004463551.1 InterPro IPR002035; KEGG: swo:Swol_1717 hypothetical protein; SMART: von Willebrand factor type A; SPTR: uncharacterized protein; PFAM: Aerotolerance regulator N-terminal; TIGRFAM: N-terminal double-transmembrane domain YP_004463552.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: swo:Swol_1718 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF58 YP_004463553.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR003593: IPR011703: IPR016366; KEGG: swo:Swol_1719 methanol dehydrogenase regulator; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: Methanol dehydrogenase regulator; PFAM: ATPase associated with various cellular activities (AAA) YP_004463554.1 KEGG: bbe:BBR47_50280 hypothetical membrane protein; SPTR: Hypothetical membrane protein YP_004463555.1 KEGG: swo:Swol_1722 hypothetical protein; SPTR: uncharacterized protein YP_004463556.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: swo:Swol_1723 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004463557.1 KEGG: swo:Swol_1724 hypothetical protein; SPTR: uncharacterized protein YP_004463559.1 COGs: COG1978 conserved hypothetical protein; InterPro IPR007405; KEGG: tit:Thit_0723 protein of unknown function DUF458; PFAM: protein of unknown function DUF458; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF458) YP_004463560.1 COGs: COG1426 conserved hypothetical protein; KEGG: tte:TTE1826 hypothetical protein; SPTR: uncharacterized protein YP_004463561.1 COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814: IPR004636; KEGG: cth:Cthe_1866 acetylornithine aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases YP_004463562.1 COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR001317: IPR011702: IPR006220: IPR017926: IPR 002474: IPR000991: IPR006274; KEGG: cce:Ccel_2913 carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_004463563.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001940: IPR001478: IPR001254; KEGG: cth:Cthe_2513 peptidase S1 and S6, chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF) YP_004463564.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR017926: IPR004468: IPR017456: IPR000991; KEGG: cac:CA_C2892 CTP synthetase; PFAM: CTP synthase-like; glutamine amidotransferase class-I; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase YP_004463565.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR004358: IPR005467: IPR000014: IPR003661: IPR 003594: IPR013656; KEGG: tex:Teth514_1996 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004463566.1 KEGG: mcu:HMPREF0573_10411 hypothetical protein; SPTR: uncharacterized protein YP_004463567.1 COGs: COG0018 Arginyl-tRNA synthetase; InterPro IPR005148: IPR008909; KEGG: tmt:Tmath_2120 arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain protein; arginyl tRNA synthetase domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain YP_004463568.1 COGs: COG0796 Glutamate racemase; InterPro IPR018187: IPR004391: IPR015942; KEGG: ate:Athe_2038 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Glutamate racemase; SPTR: Glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_004463569.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR000291: IPR011761: IPR005905: IPR011127: IPR 011095; KEGG: tmt:Tmath_2122 D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_004463570.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR007887: IPR005311: IPR001460; KEGG: clj:CLJU_c06020 beta-lactam-inducible penicillin-binding protein; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; NTF2 domain protein transpeptidase; SPTR: Penicillin-binding protein 2 (Serine-type D-Ala-D-Ala carboxypeptidase); PFAM: Penicillin binding protein transpeptidase domain; NTF2-like N-terminal transpeptidase domain; Penicillin-binding Protein dimerisation domain YP_004463571.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: csc:Csac_0600 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463573.1 COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR007235: IPR020023; KEGG: tmt:Tmath_0719 pseudaminic acid biosynthesis-associated protein PseG; PFAM: Glycosyltransferase 28 domain; SPTR: Pseudaminic acid biosynthesis-associated protein PseG; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG; PFAM: Glycosyltransferase 28 C-terminal domain; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG YP_004463574.1 COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: cby:CLM_3087 polysaccharide biosynthesis protein; PFAM: acylneuraminate cytidylyltransferase; SPTR: Polysaccharide biosynthesis protein; PFAM: Cytidylyltransferase YP_004463575.1 COGs: COG2089 Sialic acid synthase; InterPro IPR006190: IPR013132: IPR013974; KEGG: tit:Thit_0481 N-acetylneuraminate synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: NeuB family protein; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase YP_004463576.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: cbk:CLL_A0825 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: hydrolase; PFAM: haloacid dehalogenase-like hydrolase YP_004463577.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR011761: IPR003806; KEGG: cbk:CLL_A0824 carbamoyl phosphate synthase-like protein; PFAM: protein of unknown function DUF201; SPTR: ATP domain protein; PFAM: ATP-grasp domain YP_004463578.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: sti:Sthe_3174 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004463579.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653: IPR020026; KEGG: cth:Cthe_2221 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase YP_004463580.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: tmt:Tmath_0714 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase YP_004463581.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: tmt:Tmath_0713 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein CapD; PFAM: Polysaccharide biosynthesis protein YP_004463582.1 COGs: COG2604 conserved hypothetical protein; InterPro IPR002826; KEGG: tit:Thit_0477 protein of unknown function DUF115; PFAM: protein of unknown function DUF115; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF115 YP_004463583.1 KEGG: tit:Thit_0476 hypothetical protein; SPTR: uncharacterized protein YP_004463584.1 COGs: COG1334 Uncharacterized flagellar protein FlaG; InterPro IPR005186; KEGG: pth:PTH_2093 hypothetical protein; PFAM: flagellar protein FlaG protein; SPTR: Uncharacterized flagellar protein FlaG; PFAM: FlaG protein YP_004463585.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492: IPR001029; KEGG: tte:TTE0499 flagellin-like protein; PFAM: flagellin domain protein; SPTR: Flagellin and related hook-associated proteins; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region YP_004463586.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492: IPR001029; KEGG: cbi:CLJ_B2957 flagellin; PFAM: flagellin domain protein; SPTR: FlaA; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region YP_004463587.1 KEGG: dae:Dtox_3833 hypothetical protein; SPTR: uncharacterized protein YP_004463588.1 InterPro IPR007903: IPR014238; KEGG: drm:Dred_0688 PRC-barrel domain-containing protein; PFAM: PRC-barrel domain protein; SPTR: PRC-barrel domain protein; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain; TIGRFAM: sporulation protein, YlmC/YmxH family YP_004463589.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterPro IPR000943: IPR007627: IPR007624: IPR007630: IPR 014212: IPR014322: IPR014284; KEGG: ckr:CKR_1238 sporulation sigma factor SigG; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-G factor; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma-G factor; RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily YP_004463590.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterPro IPR000943: IPR007627: IPR007630: IPR014200: IPR 014284: IPR016263; KEGG: drm:Dred_0686 sporulation sigma factor SigE; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-E factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-E factor YP_004463591.1 InterPro IPR005081; KEGG: amt:Amet_2872 peptidase U4, sporulation factor SpoIIGA; PFAM: peptidase U4 sporulation factor SpoIIGA; SPTR: Peptidase U4, sporulation factor SpoIIGA; TIGRFAM: sigma-E processing peptidase SpoIIGA; PFAM: Sporulation factor SpoIIGA; TIGRFAM: sigma-E processing peptidase SpoIIGA YP_004463592.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: cdl:CDR20291_0892 cell surface protein ( N-acetylmuramoyl-L-alanine amidase); PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004463593.1 COGs: COG0206 Cell division GTPase; InterPro IPR000158: IPR020805: IPR003008: IPR018316; KEGG: amt:Amet_2873 cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004463594.1 COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494: IPR020823; KEGG: tmt:Tmath_1468 cell division protein FtsA; PFAM: cell division protein FtsA; SPTR: Cell division protein FtsA; TIGRFAM: cell division protein FtsA; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA YP_004463595.1 COGs: COG3856 conserved hypothetical protein (small basic protein); InterPro IPR009709; KEGG: tjr:TherJR_2154 protein of unknown function DUF1290; PFAM: protein of unknown function DUF1290; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1290) YP_004463596.1 COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: tpd:Teth39_1999 hypothetical protein; PFAM: protein of unknown function DUF881; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF881) YP_004463597.1 COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: tmt:Tmath_1470 protein of unknown function DUF881; PFAM: protein of unknown function DUF881; SPTR: uncharacterized protein; PFAM: AT-hook-containing transcription factor; Bacterial protein of unknown function (DUF881) YP_004463598.1 COGs: COG1589 Cell division septal protein; InterPro IPR013685; KEGG: cdf:CD2650 cell division protein; PFAM: Polypeptide-transport-associated domain protein FtsQ-type; SPTR: cell division protein; PFAM: Cell division protein FtsQ; POTRA domain, FtsQ-type YP_004463599.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR005750: IPR001986; KEGG: aoe:Clos_1380 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004463600.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR006009: IPR004276: IPR007235; KEGG: tpd:Teth39_0813 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; PFAM: glycosyl transferase 28; Glycosyltransferase 28 domain; SPTR:UDP-N-acetylglucosamine--N-acetylmuramyl- (Pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; TIGRFAM:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: Glycosyltransferase 28 N-terminal domain; Glycosyltransferase 28 C-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_004463601.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR013438: IPR013437; KEGG: tte:TTE1646 cell division membrane protein; PFAM: cell cycle protein; SPTR: Bacterial cell division membrane protein; TIGRFAM: stage V sporulation protein E; cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: stage V sporulation protein E; cell division protein FtsW YP_004463602.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR005762: IPR013221: IPR004101; KEGG: tpd:Teth39_0811 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004463603.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480: IPR003524: IPR018481; KEGG: amt:Amet_2882 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4, conserved region; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR:Phospho-N-acetylmuramoyl-pentapeptide-transfer ase; TIGRFAM:phospho-N-acetylmuramoyl-pentapeptide-trans ferase; PFAM: Glycosyl transferase 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase YP_004463604.1 COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR016160: IPR000713: IPR013221: IPR004101: IPR 005863; KEGG: tpd:Teth39_0809 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- -D-alanyl- D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-d iaminopimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_004463605.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR018109: IPR005761: IPR000713: IPR013221: IPR 004101; KEGG: tte:TTE1649 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramyl-tripeptide synthetase; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase YP_004463606.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR005311: IPR001460: IPR011927; KEGG: tmt:Tmath_1479 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Stage V sporulation protein D; TIGRFAM: stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: stage V sporulation protein D YP_004463607.1 KEGG: tit:Thit_1489 cell division protein FtsL; SPTR: Cell division protein FtsL; PFAM: Cell division protein FtsL; TIGRFAM: cell division protein FtsL YP_004463608.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: sth:STH1201 S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: MraW methylase; TIGRFAM: S-adenosyl-methyltransferase MraW YP_004463609.1 COGs: COG2001 conserved hypothetical protein; InterPro IPR003444: IPR020603; KEGG: tmt:Tmath_1482 MraZ protein; PFAM: MraZ domain; SPTR: Protein mraZ; TIGRFAM: MraZ protein; PFAM: MraZ protein; TIGRFAM: mraZ protein YP_004463610.1 COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR000623: IPR011994; KEGG: cth:Cthe_0712 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase YP_004463611.1 COGs: COG4401 Chorismate mutase; InterPro IPR008243; KEGG: slp:Slip_1766 chorismate mutase; PFAM: Chorismate mutase of the AroH class; SPTR: Chorismate mutase; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase type I; TIGRFAM: monofunctional chorismate mutase, gram positive type, clade 1 YP_004463612.1 KEGG: cce:Ccel_1731 hypothetical protein; SPTR: uncharacterized protein; PFAM: HutP YP_004463613.1 KEGG: cpy:Cphy_0951 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004463616.1 COGs: COG2247 cell wall-binding domain; InterPro IPR003343: IPR008009: IPR007253; KEGG: dhd:Dhaf_1937 cell wall binding repeat 2-containing protein; PFAM: Ig family protein; Ig domain protein group 2 domain protein; cell wall binding repeat 2-containing protein; SPTR: uncharacterized protein; PFAM: cell wall binding repeat 2 YP_004463617.1 KEGG: gga:415388 tight junction protein 1 (zona occludens 1); SPTR: uncharacterized protein YP_004463618.1 KEGG: swo:Swol_1080 ATP-dependent transcriptional regulator-like protein; SPTR: uncharacterized protein YP_004463619.1 KEGG: cno:NT01CX_0786 hypothetical protein; SPTR: uncharacterized protein YP_004463620.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: cac:CA_C0266 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004463621.1 KEGG: edi:EDI_340570 protein serine/threonine kinase; SPTR: Protein serine/threonine kinase YP_004463622.1 KEGG: dhd:Dhaf_3801 hypothetical protein; SPTR: uncharacterized protein YP_004463623.1 KEGG: mvo:Mvol_0865 CRISPR-associated protein TM1812; SPTR: CRISPR-associated protein TM1812 YP_004463625.1 KEGG: bha:BH3699 hypothetical protein; SPTR: BH3699 protein YP_004463626.1 KEGG: dhd:Dhaf_3801 hypothetical protein; SPTR: uncharacterized protein YP_004463627.1 KEGG: amt:Amet_3865 hypothetical protein; SPTR: uncharacterized protein YP_004463628.1 KEGG: cce:Ccel_2583 hypothetical protein; SPTR: uncharacterized protein YP_004463629.1 KEGG: cpv:cgd4_1270 transcription factor TFIIIB, SANT domain; SPTR: Flagellar basal-body rod protein B YP_004463630.1 KEGG: tit:Thit_2193 hypothetical protein; SPTR: uncharacterized protein YP_004463631.1 KEGG: tit:Thit_2194 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004463633.1 COGs: COG0151 Phosphoribosylamine-glycine ligase; InterPro IPR020559: IPR011761: IPR000115: IPR020562: IPR 020561: IPR020560; KEGG: cth:Cthe_1245 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase YP_004463634.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982: IPR011607: IPR002695; KEGG: cth:Cthe_1246 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_004463635.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR001555: IPR002376: IPR004607; KEGG: tle:Tlet_1910 phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; SPTR: Phosphoribosylglycinamide formyltransferase; TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_004463636.1 COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728: IPR010918: IPR004733; KEGG: cce:Ccel_2183 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase YP_004463637.1 COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR017932: IPR000583: IPR000836: IPR005854; KEGG: cth:Cthe_1249 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; phosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; Glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase YP_004463638.1 COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR010074: IPR000728: IPR010918; KEGG: amt:Amet_0921 phosphoribosylformylglycinamidine synthase II; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase 2; TIGRFAM: phosphoribosylformylglycinamidine synthase II; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase II YP_004463639.1 COGs: COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain; InterPro IPR017926: IPR010075: IPR011698; KEGG: drm:Dred_2367 phosphoribosylformylglycinamidine synthase I; PFAM: CobB/CobQ domain protein glutamine amidotransferase; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase I; TIGRFAM: phosphoribosylformylglycinamidine synthase I; PFAM: CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: phosphoribosylformylglycinamidine synthase I YP_004463640.1 COGs: COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase PurS component; InterPro IPR003850; KEGG: lsg:lse_1743 phosphoribosylformylglycinamidine synthase; PFAM: phosphoribosylformylglycinamidine synthetase PurS; SPTR: Phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein YP_004463641.1 COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR018236: IPR001636; KEGG: ate:Athe_1452 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004463642.1 COGs: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: cth:Cthe_1250 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: Phosphoribosylaminoimidazole carboxylase; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_004463644.1 COGs: COG2252 Permease; InterPro IPR006043; KEGG: cbi:CLJ_B3155 xanthine/uracil permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil permease; PFAM: Permease YP_004463645.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterPro IPR011702: IPR001317: IPR017926: IPR000991: IPR 001674: IPR004739; KEGG: cth:Cthe_0375 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase, large subunit; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit YP_004463646.1 COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: cth:Cthe_0369 hypothetical protein; PFAM: protein of unknown function DUF111; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF111; TIGRFAM: conserved hypothetical protein TIGR00299 YP_004463647.1 COGs: COG0851 Septum formation topological specificity factor; InterPro IPR005527; KEGG: aoe:Clos_1759 cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; SPTR: Cell division topological specificity factor; TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; TIGRFAM: cell division topological specificity factor MinE YP_004463648.1 COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223; KEGG: cth:Cthe_0093 septum site-determining protein MinD; SPTR: Septum site-determining protein MinD; TIGRFAM: septum site-determining protein MinD; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD YP_004463649.1 COGs: COG0850 Septum formation inhibitor; InterPro IPR013033: IPR005526; KEGG: tpd:Teth39_1448 septum formation inhibitor; PFAM: Septum formation inhibitor MinC; SPTR: Probable septum site-determining protein minC; TIGRFAM: septum site-determining protein MinC; PFAM: Septum formation inhibitor MinC, C-terminal domain; Septum formation inhibitor MinC, N-terminal domain; TIGRFAM: septum site-determining protein MinC YP_004463650.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460: IPR017790; KEGG: tte:TTE0901 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Cell division protein FtsI/penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2 YP_004463651.1 InterPro IPR007227; KEGG: cbh:CLC_2897 rod shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD YP_004463652.1 COGs: COG1792 Cell shape-determining protein; InterPro IPR007221: IPR005223; KEGG: tte:TTE0899 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein; TIGRFAM: rod shape-determining protein MreC; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC YP_004463653.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: cth:Cthe_0088 rod shape-determining protein MreB; PFAM: cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004463654.1 COGs: COG2003 DNA repair protein; InterPro IPR020891: IPR001405; KEGG: tpd:Teth39_1453 DNA repair protein RadC; PFAM: DNA repair protein RadC; SPTR: DNA repair protein RadC; TIGRFAM: DNA repair protein RadC; PFAM: Protein of unknown function (DUF2466); Helix-hairpin-helix motif; TIGRFAM: DNA repair protein radc YP_004463655.1 COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: aoe:Clos_1767 maf protein; PFAM: Maf family protein; SPTR: Maf-like protein Clos_1767; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein YP_004463656.1 KEGG: tte:TTE0895 hypothetical protein; SPTR: uncharacterized protein YP_004463657.1 KEGG: tpd:Teth39_0253 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004463658.1 COGs: COG1190 Lysyl-tRNA synthetase (class II); InterPro IPR018149: IPR006195: IPR002313: IPR004365: IPR 004364; KEGG: ate:Athe_0659 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial YP_004463659.1 COGs: COG0782 Transcription elongation factor; InterPro IPR018151: IPR001437: IPR006359; KEGG: cth:Cthe_2897 transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain-containing protein; SPTR: Transcription elongation factor; TIGRFAM: transcription elongation factor GreA; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA YP_004463660.1 KEGG: dae:Dtox_0249 shikimate/quinate 5-dehydrogenase; SPTR: Shikimate/quinate 5-dehydrogenase YP_004463661.1 KEGG: tpd:Teth39_0315 hypothetical protein; SPTR: uncharacterized protein YP_004463662.1 InterPro IPR001387; KEGG: tte:TTE2376 hypothetical protein; PFAM: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004463663.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR018517: IPR001269: IPR004652; KEGG: aoe:Clos_0447 nifR3 family TIM-barrel protein; PFAM: dihydrouridine synthase DuS; SPTR: tRNA-dihydrouridine synthase B; TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, nifR3 family YP_004463664.1 KEGG: sii:LD85_0415 methane/phenol/toluene hydroxylase; SPTR: Methane/phenol/toluene hydroxylase YP_004463665.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638: IPR000056; KEGG: tmt:Tmath_0853 quinolinate phosphoribosyl transferase; PFAM: Quinolinate phosphoribosyl transferase; ribulose-phosphate 3-epimerase; SPTR: Quinolinate phosphoribosyl transferase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain YP_004463666.1 KEGG: sro:Sros_1227 hypothetical protein; SPTR: ABC superfamily ATP binding cassette transporter, binding protein YP_004463667.1 InterPro IPR010897; KEGG: cth:Cthe_1328 stage II sporulation P; PFAM: Stage II sporulation P family protein; SPTR: Stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation protein P (SpoIIP); TIGRFAM: stage II sporulation protein P YP_004463668.1 InterPro IPR005080; KEGG: cth:Cthe_1038 germination protease; PFAM: peptidase M63 germination protease; PRIAM: GPR endopeptidase; SPTR: Spore protease; TIGRFAM: spore protease; PFAM: Germination protease; TIGRFAM: GPR endopeptidase YP_004463669.1 InterPro IPR002583; KEGG: cno:NT01CX_0065 30S ribosomal protein S20; PFAM: ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: ribosomal protein S20; PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_004463670.1 COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: cth:Cthe_0717 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain YP_004463671.1 InterPro IPR011437; KEGG: nth:Nther_2274 protein of unknown function DUF1540; PFAM: protein of unknown function DUF1540; SPTR: uncharacterized protein; PFAM: Domain of Unknown Function (DUF1540) YP_004463672.1 COGs: COG1586 S-adenosylmethionine decarboxylase; InterPro IPR003826: IPR017716; KEGG: cth:Cthe_0715 S-adenosylmethionine decarboxylase proenzyme; PFAM: S-adenosylmethionine decarboxylase related; SPTR: S-adenosylmethionine decarboxylase proenzyme; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme; PFAM: S-adenosylmethionine decarboxylase; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme, Bacillus form YP_004463673.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR000110: IPR003029: IPR003451; KEGG: cth:Cthe_0714 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; PFAM: LytB protein; RNA binding S1 domain protein; SPTR: Hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; S1 RNA binding domain; TIGRFAM: ribosomal protein S1; (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) YP_004463674.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611: IPR017583; KEGG: cbt:CLH_2876 1-phosphofructokinase; PFAM: PfkB domain protein; SPTR: 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: tagatose-6-phosphate kinase; 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase YP_004463675.1 COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001347: IPR019490: IPR011857; KEGG: hor:Hore_22730 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); SPTR: Phosphoglucose/phosphomannose isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase YP_004463676.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR011289; KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; class II aldolase, tagatose bisphosphate family; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist YP_004463677.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123: IPR004552; KEGG: tit:Thit_1146 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004463678.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: lmc:Lm4b_02451 prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004463679.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: hau:Haur_0891 glycosidase PH1107-related; PFAM: glycosidase related protein; SPTR: Glycosidase PH1107-related; PFAM: Domain of unknown function (DUF377) YP_004463680.1 InterPro IPR001647; KEGG: tjr:TherJR_2831 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family YP_004463681.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: aoe:Clos_2611 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004463682.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR003997: IPR006143; KEGG: aoe:Clos_2612 RND family efflux transporter MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004463683.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483: IPR018484: IPR018485: IPR006000; KEGG: cce:Ccel_3431 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase YP_004463684.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: ttr:Tter_1113 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004463685.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2464 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463686.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_3654 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463687.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; KEGG: gym:GYMC10_4677 extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463688.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018062: IPR018060: IPR000005; KEGG: pjd:Pjdr2_3656 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463689.1 COGs: COG4359 conserved hypothetical protein; InterPro IPR006384: IPR006383; KEGG: tit:Thit_2133 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: HAD-superfamily hydrolase subfamily IB hypothetical 1; SPTR: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Phosphatase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase YP_004463690.1 KEGG: gym:GYMC10_2732 hypothetical protein; SPTR: uncharacterized protein YP_004463691.1 InterPro IPR002781; KEGG: cce:Ccel_2539 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004463692.1 InterPro IPR002781; KEGG: cth:Cthe_1215 permease; PFAM: protein of unknown function DUF81; SPTR: Permease; PFAM: Sulfite exporter TauE/SafE YP_004463693.1 COGs: COG0525 Valyl-tRNA synthetase; InterPro IPR019754: IPR001412: IPR002300: IPR013155: IPR 019499: IPR002303; KEGG: cth:Cthe_0324 valyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA binding arm; SPTR: Valyl-tRNA synthetase; TIGRFAM: valyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase YP_004463694.1 COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462: IPR004570; KEGG: tex:Teth514_2221 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004463695.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: cth:Cthe_0419 peptidase M16-like protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16-like protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase M16) YP_004463696.1 COGs: COG1825 Ribosomal protein L25 (general stress protein Ctc); InterPro IPR020055: IPR001021; KEGG: tpd:Teth39_0558 50S ribosomal protein L25/general stress protein Ctc; PFAM: Ribosomal protein L25-like; SPTR: 50S ribosomal protein L25; TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form YP_004463697.1 COGs: COG0301 Thiamine biosynthesis ATP pyrophosphatase; InterPro IPR004114: IPR003720: IPR020536; KEGG: aoe:Clos_1813 thiamine biosynthesis protein ThiI; PFAM: Thiamine biosynthesis protein-like; THUMP domain-containing protein; SPTR: Probable tRNA sulfurtransferase; TIGRFAM: thiamine biosynthesis/tRNA modification protein ThiI; PFAM: Thiamine biosynthesis protein (ThiI); THUMP domain; TIGRFAM: thiazole biosynthesis/tRNA modification protein ThiI YP_004463698.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR016454; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; PFAM: Aminotransferase class-V YP_004463699.1 KEGG: cce:Ccel_0393 hypothetical protein; SPTR: uncharacterized protein YP_004463700.1 COGs: COG0333 Ribosomal protein L32; InterPro IPR002677; KEGG: afn:Acfer_1398 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: Ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32 YP_004463701.1 COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: cpf:CPF_1976 hypothetical protein; PFAM: protein of unknown function DUF177; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1399 YP_004463702.1 COGs: COG0282 Acetate kinase; InterPro IPR000890: IPR004372; KEGG: cth:Cthe_1028 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase; TIGRFAM: acetate kinase YP_004463703.1 COGs: COG0280 Phosphotransacetylase; InterPro IPR002505: IPR004614: IPR012147; KEGG: tte:TTE1482 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphotransacetylase; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase YP_004463704.1 COGs: COG3949 Uncharacterized membrane protein; KEGG: cth:Cthe_0643 hypothetical protein; SPTR: uncharacterized protein YP_004463705.1 COGs: COG0281 Malic enzyme; InterPro IPR015884: IPR012301: IPR012302; KEGG: cbh:CLC_0304 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: Malic enzyme; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_004463706.1 COGs: COG2206 HD-GYP domain; InterPro IPR003607: IPR006674: IPR006675; KEGG: cth:Cthe_0898 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004463707.1 COGs: COG3707 Response regulator with antiterminator output domain; InterPro IPR001789: IPR005561: IPR008327; KEGG: mta:Moth_1295 response regulator receiver/ANTAR domain-containing protein; PFAM: ANTAR domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver (CheY-like) and ANTAR domain protein; PFAM: Response regulator receiver domain; ANTAR domain YP_004463708.1 COGs: COG0174 Glutamine synthetase; InterPro IPR008147: IPR008146: IPR004809; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I YP_004463709.1 COGs: COG0070 Glutamate synthase domain 3; InterPro IPR002489: IPR012061; KEGG: tpd:Teth39_1657 glutamate synthase alpha subunit; PFAM: glutamate synthase alpha subunit domain protein; SPTR: Glutamate synthase alpha subunit domain protein; PFAM: GXGXG motif YP_004463710.1 COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027; KEGG: tmt:Tmath_1317 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004463711.1 COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; InterPro IPR017900: IPR017896; KEGG: tex:Teth514_0560 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain YP_004463712.1 COGs: COG0069 Glutamate synthase domain 2; InterPro IPR017900: IPR017896: IPR002932; KEGG: tmt:Tmath_1319 glutamate synthase (NADPH); PFAM: ferredoxin-dependent glutamate synthase; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase (NADPH); PFAM: Conserved region in glutamate synthase YP_004463713.1 COGs: COG0067 Glutamate synthase domain 1; InterPro IPR017932: IPR000583: IPR012375; KEGG: tjr:TherJR_0711 glutamine amidotransferase class-II; PFAM: glutamine amidotransferase class-II; SPTR: Glutamine amidotransferase class-II; PFAM: Glutamine amidotransferases class-II YP_004463714.1 COGs: COG0289 Dihydrodipicolinate reductase; InterPro IPR000846: IPR011770; KEGG: cce:Ccel_0519 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_004463715.1 COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: tpd:Teth39_0754 NifU domain-containing protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like domain YP_004463716.1 COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302: IPR001412: IPR015413: IPR013155; KEGG: cth:Cthe_1237 leucyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family YP_004463717.1 COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: drm:Dred_2516 iojap-like protein; PFAM: Iojap-related protein; SPTR: Iojap-like protein; TIGRFAM: iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein YP_004463718.1 KEGG: amt:Amet_4601 hypothetical protein; SPTR: uncharacterized protein YP_004463719.1 InterPro IPR004761; KEGG: mta:Moth_1012 spore germination protein; PFAM: Spore germination protein; SPTR: Spore germination protein; TIGRFAM: spore germination protein; PFAM: Spore germination protein; TIGRFAM: spore germination protein (amino acid permease) YP_004463720.1 InterPro IPR008844; KEGG: mta:Moth_1013 spore germination B3 GerAC like; PFAM: spore germination B3 GerAC family protein; SPTR: Spore germination B3 GerAC like; TIGRFAM: germination protein, Ger(x)C family; PFAM: Spore germination B3/ GerAC like, C-terminal; TIGRFAM: germination protein, Ger(x)C family YP_004463721.1 InterPro IPR004995; KEGG: mta:Moth_1014 GerA spore germination protein; PFAM: GerA spore germination protein; SPTR: GerA spore germination protein; PFAM: Bacillus/Clostridium GerA spore germination protein YP_004463722.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterPro IPR018239: IPR001357: IPR013840: IPR003583: IPR 013839: IPR004150: IPR004149: IPR001679; KEGG: tpd:Teth39_1694 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; BRCT domain protein; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase; Helix-hairpin-helix DNA-binding class 1; BRCT domain protein; SPTR: DNA ligase; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent YP_004463723.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212: IPR005751; KEGG: tex:Teth514_0537 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA YP_004463724.1 COGs: COG4496 conserved hypothetical protein; InterPro IPR000831: IPR013368; KEGG: tit:Thit_0588 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial YP_004463725.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: tpd:Teth39_2012 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase YP_004463726.1 COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475: IPR005476; KEGG: cth:Cthe_2705 transketolase subunit B; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_004463727.1 COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: tmt:Tmath_1823 transketolase domain protein; PFAM: Transketolase domain-containing protein; SPTR: Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain YP_004463728.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740: IPR019264; KEGG: tpd:Teth39_0490 hypothetical protein; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004463729.1 COGs: COG1193 Mismatch repair ATPase (MutS family); InterPro IPR000432: IPR002625: IPR007696: IPR005747; KEGG: cth:Cthe_1014 MutS2 family protein; PFAM: Smr protein/MutS2; DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; Smr protein/MutS2; SPTR: MutS2 protein; TIGRFAM: MutS2 family protein; PFAM: MutS domain V; Smr domain; TIGRFAM: MutS2 family protein YP_004463730.1 InterPro IPR007838; KEGG: cth:Cthe_2088 hypothetical protein; PFAM: protein of unknown function DUF710; SPTR: uncharacterized protein; PFAM: Cell division protein ZapA YP_004463731.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: cth:Cthe_0215 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial YP_004463732.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR006195: IPR004188: IPR002319: IPR004529; KEGG: tpd:Teth39_0771 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: Phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_004463733.1 InterPro IPR019239; KEGG: tmt:Tmath_2080 protein of unknown function DUF2191; PFAM: Protein of unknown function DUF2191; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2191) YP_004463734.1 InterPro IPR002716; KEGG: tmt:Tmath_2081 PilT protein domain protein; PFAM: PilT protein domain protein; SPTR: PilT protein domain protein; PFAM: PIN domain YP_004463735.1 COGs: COG2247 cell wall-binding domain; InterPro IPR003961: IPR004843: IPR007253; KEGG: fma:FMG_1259 N-acetylmuramoyl-L-alanine amidase; PFAM: metallophosphoesterase; Fibronectin type III domain protein; cell wall binding repeat 2-containing protein; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: Calcineurin-like phosphoesterase; cell wall binding repeat 2 YP_004463736.1 KEGG: clj:CLJU_c29860 hypothetical protein; SPTR: uncharacterized protein YP_004463737.1 COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537; KEGG: cth:Cthe_1222 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase; RNA 2'-O ribose methyltransferase substrate binding YP_004463738.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037; KEGG: amt:Amet_1637 TrkA domain-containing protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain; TrkA-C domain YP_004463739.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445: IPR004772; KEGG: tmt:Tmath_0230 potassium uptake protein, TrkH family; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: Potassium uptake protein, TrkH family; TIGRFAM: potassium uptake protein, TrkH family; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_004463740.1 KEGG: tmt:Tmath_1709 hypothetical protein; SPTR: uncharacterized protein YP_004463741.1 KEGG: mar:MAE_37490 hypothetical protein; SPTR: uncharacterized protein YP_004463742.1 COGs: COG0480 Translation elongation factors (GTPase); InterPro IPR000795: IPR004161: IPR005517: IPR000640: IPR 004540: IPR005225; KEGG: tte:TTE2333 elongation factor G; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Translation elongation and release factors (GTPases); TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004463743.1 COGs: COG0082 Chorismate synthase; InterPro IPR000408: IPR020541: IPR000453; KEGG: tjr:TherJR_1742 chorismate synthase; PFAM: chorismate synthase; PRIAM: Chorismate synthase; SPTR: Chorismate synthase; TIGRFAM: chorismate synthase; PFAM: Chorismate synthase; TIGRFAM: chorismate synthase YP_004463744.1 COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR016037: IPR002658: IPR016303; KEGG: pth:PTH_1132 3-dehydroquinate synthetase; PFAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase YP_004463745.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839; KEGG: csc:Csac_2697 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_004463746.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218: IPR006268; KEGG: cth:Cthe_1795 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase YP_004463747.1 COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099: IPR002912; KEGG: cth:Cthe_1796 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; ACT domain YP_004463748.1 COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; InterPro IPR001986: IPR006264: IPR016228; KEGG: bbe:BBR47_24810 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase YP_004463749.1 InterPro IPR001387; KEGG: gym:GYMC10_5352 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix YP_004463750.1 COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR017871: IPR003439: IPR003593: IPR004602; KEGG: cth:Cthe_0311 excinuclease ABC subunit A; PFAM: ABC transporter related; SPTR: Excinuclease ABC subunit A; TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004463751.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; InterPro IPR001943: IPR014021: IPR001650: IPR014001: IPR 004807: IPR006935; KEGG: cth:Cthe_0309 excinuclease ABC subunit B; PFAM: helicase domain protein; type III restriction protein res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: UvrABC system protein B; TIGRFAM: excinuclease ABC, B subunit; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit YP_004463752.1 InterPro IPR001478; KEGG: tte:TTE1973 trypsin-like serine protease; PFAM: PDZ/DHR/GLGF domain protein; SPTR: Trypsin-like serine protease, typically periplasmic, contain C-terminal PDZ domain; PFAM: PDZ domain (Also known as DHR or GLGF) YP_004463753.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151: IPR004447; KEGG: amt:Amet_4128 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: Peptidase S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004463754.1 COGs: COG1305 Transglutaminase-like protein; InterPro IPR002931; KEGG: tex:Teth514_0930 transglutaminase domain-containing protein; PFAM: transglutaminase domain-containing protein; SMART: transglutaminase domain-containing protein; SPTR: Transglutaminase domain protein; PFAM: Transglutaminase-like superfamily YP_004463755.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: aoe:Clos_2652 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF58 YP_004463756.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR003593: IPR011703: IPR016366; KEGG: tte:TTE2215 MoxR-like ATPase; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: MoxR-like ATPases; PFAM: ATPase associated with various cellular activities (AAA) YP_004463757.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR000103: IPR013027; KEGG: cbi:CLJ_B3741 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004463758.1 KEGG: ttr:Tter_2228 hypothetical protein; SPTR: uncharacterized protein YP_004463759.1 COGs: COG2861 conserved hypothetical protein; InterPro IPR006837; KEGG: amt:Amet_4438 protein of unknown function DUF610, YibQ; PFAM: protein of unknown function DUF610 YibQ; SPTR: uncharacterized protein; PFAM: Divergent polysaccharide deacetylase YP_004463760.1 COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR013027: IPR004792: IPR006076; KEGG: nth:Nther_0129 FAD dependent oxidoreductase; PFAM: HI0933 family protein; FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004463761.1 COGs: COG2440 Ferredoxin-like protein; InterPro IPR017896; KEGG: hor:Hore_00130 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; manually curated YP_004463762.1 COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: ate:Athe_2544 BioY protein; PFAM: BioY protein; SPTR: BioY protein; PFAM: BioY family YP_004463763.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: mta:Moth_2111 uroporphyrinogen-III decarboxylase-like; SPTR: Uroporphyrinogen-III decarboxylase-like; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463764.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mac:MA3658 iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: Iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase YP_004463765.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: bcl:ABC3284 sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Sugar phosphate isomerases/epimerase; PFAM: Xylose isomerase-like TIM barrel YP_004463766.1 COGs: COG1832 CoA-binding protein; InterPro IPR003781; KEGG: tmt:Tmath_1054 CoA-binding domain protein; PFAM: CoA-binding domain protein; SPTR: CoA-binding domain protein YP_004463767.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328: IPR013154: IPR013149; KEGG: ttr:Tter_0832 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004463768.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tte:TTE0090 transcriptional regulator; PFAM: ROK family protein; SPTR: Transcriptional regulator; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004463769.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500: IPR004785; KEGG: tau:Tola_1979 ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose 5-phosphate isomerase B; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004463770.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: gme:Gmet_0067 ribulose-5-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase; TIGRFAM: ribulose-phosphate 3-epimerase YP_004463771.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: tmt:Tmath_0260 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family YP_004463772.1 KEGG: tna:CTN_0359 ureidoglycolate hydrolase; SPTR: Ureidoglycolate hydrolase; PFAM: Ureidoglycolate hydrolase YP_004463773.1 InterPro IPR006104; KEGG: dtu:Dtur_0165 hypothetical protein; PFAM: glycoside hydrolase 2 sugar binding; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolases family 2, sugar binding domain YP_004463774.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: cth:Cthe_2785 MtaA/CmuA family methyltransferase; SPTR: Methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463775.1 KEGG: ade:Adeh_4311 hypothetical protein; SPTR: uncharacterized protein YP_004463776.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_0473 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463777.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_4133 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463778.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_3690 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463779.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR006589: IPR006047; KEGG: tpt:Tpet_1141 alpha amylase, catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Alpha amylase, catalytic region; PFAM: Alpha amylase, catalytic domain YP_004463780.1 COGs: COG2721 Altronate dehydratase; InterPro IPR001647: IPR007392; KEGG: tit:Thit_0159 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; PRIAM: Altronate dehydratase; SPTR: Altronate dehydratase; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus YP_004463781.1 InterPro IPR013974; KEGG: tpd:Teth39_1678 SAF domain-containing protein; PFAM: SAF domain protein; SPTR: SAF domain; PFAM: SAF domain YP_004463782.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR020624; KEGG: chy:CHY_1320 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase YP_004463783.1 KEGG: gtn:GTNG_1869 iron-sulfur cluster binding protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088) YP_004463784.1 COGs: COG2385 Sporulation protein and related protein; InterPro IPR013693: IPR014225: IPR013486; KEGG: tex:Teth514_0106 SpoIID/LytB domain-containing protein; PFAM: Stage II sporulation protein D; SPTR: SpoIID/LytB domain; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain YP_004463785.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR002052: IPR005750: IPR001986; KEGG: tmt:Tmath_0193 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004463786.1 KEGG: cth:Cthe_2614 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1779) YP_004463787.1 InterPro IPR001080: IPR017900: IPR017896; KEGG: mta:Moth_1832 4Fe-4S ferredoxin, iron-sulfur binding; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S binding domain YP_004463788.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: slp:Slip_1775 glycosidase-related protein; PFAM: glycosidase related protein; SPTR: Glycosidase-related protein; PFAM: Domain of unknown function (DUF377) YP_004463789.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: csc:Csac_1729 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1; PFAM: Glycosyl transferases group 1 YP_004463790.1 COGs: COG1376 conserved hypothetical protein; InterPro IPR005490: IPR002477; KEGG: clj:CLJU_c34530 hypothetical protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein; SPTR: Conserved protein (Peptidoglycan binding); PFAM: peptidoglycan binding domain; L,D-transpeptidase catalytic domain YP_004463791.1 InterPro IPR000182; KEGG: sai:Saci_2284 N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004463792.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: spl:Spea_1465 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; SPTR: Glycosyl hydrolase 109 protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004463793.1 COGs: COG3394 conserved hypothetical protein; InterPro IPR006879; KEGG: dfe:Dfer_3997 YdjC family protein; PFAM: YdjC family protein; SPTR: YdjC family protein; PFAM: YdjC-like protein YP_004463794.1 KEGG: dtu:Dtur_0165 hypothetical protein; SPTR: uncharacterized protein YP_004463795.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR020449: IPR018060: IPR001789: IPR000005; KEGG: gym:GYMC10_4467 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463796.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003660: IPR010559: IPR003594; KEGG: cce:Ccel_1250 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004463797.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: dth:DICTH_1485 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Bacterial extracellular solute-binding protein, ; PFAM: Bacterial extracellular solute-binding protein YP_004463798.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: dtu:Dtur_1588 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463799.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: dtu:Dtur_1589 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463800.1 KEGG: dtu:Dtur_1590 hypothetical protein; SPTR: uncharacterized protein YP_004463801.1 InterPro IPR013026: IPR013017: IPR001258; KEGG: dtu:Dtur_1591 NHL repeat containing protein; PFAM: NHL repeat containing protein; SPTR: NHL repeat containing protein; PFAM: NHL repeat; Tetratricopeptide repeat YP_004463802.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: dtu:Dtur_1592 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463803.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: dth:DICTH_1483 ABC transporter, membrane spanning protein (sugar); PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, membrane spanning protein (Sugar); PFAM: Binding-protein-dependent transport system inner membrane component YP_004463804.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006162: IPR006059; KEGG: dth:DICTH_1484 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004463805.1 InterPro IPR003838; KEGG: pjd:Pjdr2_5946 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004463806.1 COGs: COG5520 O-Glycosyl hydrolase; InterPro IPR003961: IPR001139; KEGG: cyt:cce_2532 hypothetical protein; PFAM: Fibronectin type III domain protein; glycoside hydrolase 30; SMART: Fibronectin type III domain protein; SPTR: uncharacterized protein; PFAM: Fibronectin type III domain YP_004463807.1 InterPro IPR006626; KEGG: chu:CHU_0455 pectate lyase-related protein; SPTR: uncharacterized protein YP_004463808.1 COGs: COG0274 Deoxyribose-phosphate aldolase; InterPro IPR002915: IPR011343; KEGG: msv:Mesil_2961 deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Deoxyribose-phosphate aldolase; SPTR: Deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_004463809.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cce:Ccel_1254 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463810.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: cce:Ccel_1253 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463811.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2741 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463812.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR020449: IPR018062: IPR018060: IPR001789: IPR 000005; KEGG: gym:GYMC10_3319 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463813.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003660: IPR010559: IPR003594; KEGG: cce:Ccel_1250 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004463814.1 KEGG: lmf:LMOf2365_1057 hypothetical protein; SPTR: uncharacterized protein YP_004463815.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281: IPR001347; KEGG: bha:BH2675 RpiR transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_004463816.1 COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR001959: IPR010095; KEGG: mfs:MFS40622_1028 transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; transposase IS891/IS1136/IS1341 family; SPTR: Transposase, IS605 OrfB family, central region; TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region YP_004463817.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR018110: IPR001202: IPR013341: IPR013342; KEGG: dda:Dd703_0947 mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain YP_004463818.1 COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR013096; KEGG: dth:DICTH_0770 polyketide synthesis domain protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Polyketide synthesis domain protein; PFAM: Cupin domain YP_004463819.1 KEGG: dhd:Dhaf_2640 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004463820.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR018247: IPR012307; KEGG: cpi:Cpin_6459 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel YP_004463821.1 KEGG: cdf:CD2547 hypothetical protein; SPTR: uncharacterized protein YP_004463822.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: pjd:Pjdr2_4150 sulfatase; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004463823.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: fre:Franean1_3166 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase YP_004463824.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: oih:OB1195 hypothetical protein; SPTR: Hypothetical conserved protein; PFAM: Prolyl oligopeptidase YP_004463825.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2944 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463826.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2943 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463827.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4742 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463828.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR018062: IPR018060: IPR000005; KEGG: gym:GYMC10_3278 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004463829.1 COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR013838: IPR004646; KEGG: amt:Amet_3413 fumarate hydratase; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; SPTR: Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region YP_004463830.1 COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: tmt:Tmath_0124 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; SPTR: Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region YP_004463831.1 COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: csc:Csac_0857 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, N-terminal domain; S-adenosylmethionine synthetase, central domain; TIGRFAM: S-adenosylmethionine synthetase YP_004463832.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR016166: IPR003170: IPR006094: IPR011601; KEGG: aoe:Clos_0573 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain-containing protein; FAD linked oxidase domain protein; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004463833.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600: IPR004654; KEGG: tte:TTE1961 transcriptional regulator; PFAM: ROK family protein; SPTR: Transcriptional regulator; TIGRFAM: glucokinase, ROK family; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004463834.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141: IPR004013; KEGG: tpd:Teth39_0577 hydrolase; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: PHP domain protein; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family YP_004463835.1 COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001347: IPR019490: IPR011857; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); SPTR: Mannose-6-phosphate isomerase / glucose-6-phosphate isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase YP_004463836.1 COGs: COG1493 Serine kinase of the HPr protein regulates carbohydrate metabolism; InterPro IPR011126: IPR011104: IPR003755; KEGG: tmt:Tmath_1744 HPr kinase; PFAM: HPr serine kinase domain-containing protein; SPTR: HPr kinase; TIGRFAM: HPr(Ser) kinase/phosphatase; PFAM: HPr Serine kinase N terminus; HPr Serine kinase C-terminal domain; TIGRFAM: Hpr(Ser) kinase/phosphatase YP_004463837.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR000160: IPR003607: IPR006674: IPR006675; KEGG: cbt:CLH_1356 GGDEF/hd domain protein; PFAM: metal-dependent phosphohydrolase HD sub domain; GGDEF domain containing protein; SMART: GGDEF domain containing protein; metal-dependent phosphohydrolase HD region; SPTR: Ggdef/hd domain protein; TIGRFAM: diguanylate cyclase; metal dependent phophohydrolase; PFAM: HD domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; uncharacterized domain HDIG YP_004463838.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; InterPro IPR001943: IPR000305: IPR001162: IPR004791; KEGG: tjr:TherJR_2731 excinuclease ABC, C subunit; PFAM: excinuclease ABC C subunit domain protein; Excinuclease ABC C subunit domain protein; UvrB/UvrC protein; SMART: Excinuclease ABC C subunit domain protein; SPTR: UvrABC system protein C; TIGRFAM: excinuclease ABC, C subunit; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit YP_004463839.1 COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: tpd:Teth39_0467 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase YP_004463840.1 COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: hor:Hore_06790 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004463841.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR005476; KEGG: hor:Hore_06780 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Transketolase, C-terminal domain YP_004463842.1 InterPro IPR017900: IPR017896; KEGG: hmo:HM1_0357 4fe-4S ferredoxin, iron-sulfur binding domain protein; SPTR: 4fe-4S ferredoxin, iron-sulfur binding domain protein YP_004463843.1 KEGG: cth:Cthe_0869 hypothetical protein; SPTR: uncharacterized protein YP_004463844.1 COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tte:TTE2207 hypothetical protein; PFAM: YbbR family protein; SPTR: uncharacterized protein; PFAM: YbbR-like protein YP_004463845.1 COGs: COG1624 conserved hypothetical protein; InterPro IPR003390: IPR014046; KEGG: tte:TTE2209 hypothetical protein; PFAM: protein of unknown function DUF147; SPTR: uncharacterized protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: conserved hypothetical protein TIGR00159 YP_004463846.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR017871: IPR004089: IPR011644; KEGG: amt:Amet_1187 methyl-accepting chemotaxis sensory transducer; PFAM: Heme NO binding domain protein; chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis sensory transducer; manually curated; PFAM: Heme NO binding; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004463847.1 COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: cth:Cthe_2699 transcriptional modulator of MazE/toxin, MazF; PFAM: PemK family protein; SPTR: Transcriptional modulator of MazE/toxin, MazF; PFAM: PemK-like protein YP_004463848.1 KEGG: aoe:Clos_2274 CopG family transcriptional regulator; SPTR: transcriptional regulator, CopG family; PFAM: Ribbon-helix-helix protein, copG family YP_004463849.1 COGs: COG0063 sugar kinase; InterPro IPR004443: IPR000631: IPR017953; KEGG: slp:Slip_1786 carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain-containing protein; protein of unknown function UPF0031; SPTR: Carbohydrate kinase, YjeF related protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related YP_004463850.1 COGs: COG1406 inhibitor of MCP methylation homolog of CheC; InterPro IPR007597; KEGG: ate:Athe_2134 CheC domain protein; PFAM: CheC domain protein; SPTR: CheC domain protein; tmRNA as predicted by Rfam (RF00023), score 198.58; PFAM: CheC-like family YP_004463851.1 COGs: COG0691 tmRNA-binding protein; InterPro IPR000037: IPR020081; KEGG: tit:Thit_0932 SsrA-binding protein; PFAM: SmpB protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004463852.1 InterPro IPR014201; KEGG: csc:Csac_0537 hypothetical protein; PFAM: Sporulation stage IV protein A; SPTR: uncharacterized protein; TIGRFAM: stage IV sporulation protein A; PFAM: Stage IV sporulation protein A (spore_IV_A); TIGRFAM: stage IV sporulation protein A YP_004463853.1 COGs: COG0344 membrane protein; InterPro IPR020788: IPR003811; KEGG: tpd:Teth39_0840 membrane protein; PFAM: protein of unknown function DUF205; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase YP_004463854.1 COGs: COG1160 GTPase; InterPro IPR005225: IPR016484: IPR002917: IPR006073; KEGG: tte:TTE1619 GTP-binding protein EngA; PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein engA; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein; manually curated; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain YP_004463855.1 COGs: COG1625 Fe-S oxidoreductase related to NifB/MoaA family; InterPro IPR007549: IPR001478; KEGG: tex:Teth514_1984 hypothetical protein; PFAM: protein of unknown function DUF512; SPTR: uncharacterized protein; PFAM: PDZ domain (Also known as DHR or GLGF); Protein of unknown function (DUF512); TIGRFAM: FeS-containing Cyanobacterial-specific oxidoreductase YP_004463856.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: hor:Hore_11160 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1 YP_004463857.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: tmt:Tmath_1567 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family YP_004463858.1 KEGG: tmt:Tmath_0623 hypothetical protein; SPTR: uncharacterized protein YP_004463859.1 KEGG: cbk:CLL_A1676 hypothetical protein; SPTR: uncharacterized protein YP_004463860.1 KEGG: tmt:Tmath_0622 hypothetical protein; SPTR: uncharacterized protein YP_004463861.1 KEGG: amt:Amet_0943 hypothetical protein; SPTR: uncharacterized protein YP_004463862.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209; KEGG: tpd:Teth39_1725 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Peptidase S8 and S53 subtilisin kexin sedolisin; PFAM: Subtilase YP_004463863.1 COGs: COG0824 thioesterase; InterPro IPR006684: IPR006683; KEGG: cbe:Cbei_1957 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: Thioesterase superfamily protein; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004463864.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR012828: IPR000023: IPR015912: IPR012003; KEGG: aoe:Clos_0585 6-phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase; TIGRFAM: 6-phosphofructokinase; PFAM: Phosphofructokinase; TIGRFAM: 6-phosphofructokinase YP_004463865.1 InterPro IPR000824; KEGG: adg:Adeg_0435 transcription attenuation protein MtrB; PFAM: tryptophan RNA-binding attenuator protein; SPTR: Tryptophan RNA-binding attenuator protein; PFAM: Tryptophan RNA-binding attenuator protein YP_004463866.1 COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004805: IPR004013: IPR011708: IPR004365: IPR 003141; KEGG: tte:TTE1818 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004463867.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698: IPR000032; KEGG: tte:TTE1820 phosphotransferase system, HPr-related proteins; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, HPr-related proteins; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family YP_004463868.1 COGs: COG1481 conserved hypothetical protein; InterPro IPR003802: IPR018478; KEGG: amt:Amet_4088 hypothetical protein; PFAM: protein of unknown function DUF199; Sporulation regulator WhiA-like; SPTR: uncharacterized protein; PFAM: Sporulation Regulator WhiA N terminal; Sporulation Regulator WhiA C terminal domain; TIGRFAM: conserved hypothetical protein YP_004463869.1 COGs: COG1660 P-loop-containing kinase; InterPro IPR005337; KEGG: aoe:Clos_0574 hypothetical protein; SPTR: UPF0042 nucleotide-binding protein ClothDRAFT_1561; manually curated; PFAM: P-loop ATPase YP_004463870.1 COGs: COG0182 translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; InterPro IPR005251: IPR011559: IPR000649; KEGG: taf:THA_488 methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: Methylthioribose-1-phosphate isomerase; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-methyl-5-thioribose-1-phosphate isomerase YP_004463871.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: mvo:Mvol_0994 L-fuculose-phosphate aldolase; PFAM: class II aldolase/adducin family protein; SPTR: L-fuculose-phosphate aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004463872.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR010044: IPR000845: IPR018099; KEGG: csc:Csac_1924 methylthioadenosine phosphorylase; PFAM: purine or other phosphorylase 1; SPTR: Methylthioadenosine phosphorylase; TIGRFAM: methylthioadenosine phosphorylase; PFAM: Phosphorylase superfamily; TIGRFAM: 5'-deoxy-5'-methylthioadenosine phosphorylase YP_004463873.1 COGs: COG0661 unusual protein kinase; InterPro IPR004147: IPR002114; KEGG: mbu:Mbur_1648 2-octaprenylphenol hydroxylase; PFAM: ABC-1 domain-containing protein; SPTR: ABC1 family protein; PFAM: Lipopolysaccharide core biosynthesis protein (WaaY); ABC1 family; TIGRFAM: 2-polyprenylphenol 6-hydroxylase YP_004463874.1 KEGG: ckr:CKR_0042 hypothetical protein; SPTR: uncharacterized protein YP_004463875.1 KEGG: pkn:PKH_030690 hypothetical protein; SPTR: uncharacterized protein YP_004463876.1 COGs: COG0557 Exoribonuclease R; InterPro IPR011805: IPR004476: IPR013223: IPR001900: IPR 003029: IPR011129; KEGG: cth:Cthe_0146 ribonuclease R; PFAM: ribonuclease II; Ribonuclease B OB region domain; RNA binding S1 domain protein; SMART: Cold shock protein; SPTR: Ribonuclease R; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonuclease; PFAM: RNB domain; Ribonuclease B OB domain; S1 RNA binding domain; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonucleases YP_004463877.1 COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006675: IPR006674: IPR003607; KEGG: swo:Swol_0279 HDIG domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: HDIG domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004463878.1 InterPro IPR004692; KEGG: tmt:Tmath_1557 preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase, SecG subunit; TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_004463879.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611: IPR002173: IPR002139; KEGG: bmq:BMQ_1157 carbohydrate kinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; manually curated; PFAM: pfkB family carbohydrate kinase YP_004463880.1 COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: tit:Thit_0327 LemA family protein; PFAM: LemA family protein; SPTR: LemA family protein; PFAM: LemA family YP_004463881.1 COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: tit:Thit_0336 protein of unknown function DUF477; PFAM: protein of unknown function DUF477; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF477) YP_004463882.1 COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterPro IPR007197: IPR016431; KEGG: tpd:Teth39_0714 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004463883.1 COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750: IPR003918; KEGG: amt:Amet_1149 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains YP_004463884.1 COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: amt:Amet_1148 NADH-ubiquinone oxidoreductase, chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: NADH-ubiquinone oxidoreductase, chain 4L; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_004463885.1 InterPro IPR007182; KEGG: amt:Amet_1147 Na+/H+ antiporter MnhB subunit-related protein; PFAM: Na+/H+ antiporter MnhB subunit-related protein; SPTR: Na+/H+ antiporter MnhB subunit-related protein; PFAM: Domain related to MnhB subunit of Na+/H+ antiporter YP_004463886.1 KEGG: amt:Amet_1146 hypothetical protein; SPTR: uncharacterized protein YP_004463887.1 KEGG: amt:Amet_1145 hypothetical protein; SPTR: uncharacterized protein YP_004463888.1 COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: amt:Amet_1144 monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; SPTR: Monovalent cation/proton antiporter, MnhG/PhaG subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit YP_004463889.1 InterPro IPR007208; KEGG: amt:Amet_1143 multiple resistance and pH regulation protein F; PFAM: multiple resistance and pH regulation protein F; SPTR: Multiple resistance and pH regulation protein F; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF) YP_004463890.1 COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: amt:Amet_1142 cation antiporter; PFAM: cation antiporter; SPTR: Cation antiporter; PFAM: Na+/H+ ion antiporter subunit YP_004463891.1 COGs: COG0103 Ribosomal protein S9; InterPro IPR000754: IPR020574; KEGG: tte:TTE2256 ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16 YP_004463892.1 COGs: COG0102 Ribosomal protein L13; InterPro IPR005823: IPR005822; KEGG: cth:Cthe_1783 50S ribosomal protein L13; PFAM: ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: ribosomal protein L13; PFAM: Ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type YP_004463893.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: cpf:CPF_2202 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR:S-adenosylmethionine/tRNA-ribosyltransferase-i somerase; TIGRFAM:S-adenosylmethionine/tRNA-ribosyltransferas e-isomerase; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004463894.1 KEGG: tle:Tlet_0061 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2905) YP_004463895.1 COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: adg:Adeg_1629 protein of unknown function DUF208; PFAM: protein of unknown function DUF208; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, COG1636 YP_004463896.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; InterPro IPR004605: IPR008823: IPR008824: IPR003959: IPR 003593; KEGG: cth:Cthe_0182 Holliday junction DNA helicase RuvB; PFAM: AAA ATPase central domain protein; Holliday junction DNA helicase RuvB domain; SMART: AAA ATPase; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: Holliday junction DNA helicase RuvB; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_004463897.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterPro IPR000085: IPR013849: IPR011114: IPR003583; KEGG: cth:Cthe_0181 Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; RuvA domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit YP_004463898.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176: IPR020563; KEGG: tmt:Tmath_1061 crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_004463899.1 KEGG: tpd:Teth39_1545 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2837) YP_004463900.1 COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518: IPR018223; KEGG: cth:Cthe_0179 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase YP_004463901.1 COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049: IPR000362: IPR020557: IPR003031; KEGG: cce:Ccel_1344 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase YP_004463902.1 COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR006308: IPR006054: IPR004365: IPR004013: IPR 013520: IPR011708: IPR003141: IPR006055; KEGG: cth:Cthe_0996 DNA polymerase III PolC; PFAM: DNA polymerase III alpha subunit; Exonuclease RNase T and DNA polymerase III; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: Exonuclease; phosphoesterase PHP domain protein; SPTR: DNA polymerase III catalytic subunit, PolC type; TIGRFAM: DNA polymerase III, alpha subunit; DNA polymerase III, epsilon subunit; PFAM: DNA polymerase III polC-type N-terminus; Bacterial DNA polymerase III alpha subunit; PHP domain; Exonuclease; OB-fold nucleic acid binding domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; DNA polymerase III, alpha chain, Gram-positive type YP_004463903.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; InterPro IPR004588: IPR016425; KEGG: tpd:Teth39_1216 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PFAM: IspG family protein; SPTR: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004463904.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387: IPR008915: IPR001478; KEGG: amt:Amet_2681 membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; SPTR: membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase M50; TIGRFAM: RIP metalloprotease RseP YP_004463905.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR003821: IPR013512: IPR013644; KEGG: tte:TTE1402 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004463906.1 COGs: COG0628 permease; InterPro IPR014227: IPR002549; KEGG: dau:Daud_0614 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: uncharacterized protein; TIGRFAM: sporulation integral membrane protein YtvI; PFAM: Domain of unknown function DUF20; TIGRFAM: sporulation integral membrane protein YtvI YP_004463907.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: cno:NT01CX_2144 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase YP_004463908.1 COGs: COG0020 Undecaprenyl pyrophosphate synthase; InterPro IPR001441: IPR018520; KEGG: drm:Dred_1973 undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: uncharacterized protein; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_004463909.1 COGs: COG0233 Ribosome recycling factor; InterPro IPR002661: IPR015998; KEGG: tpd:Teth39_1222 ribosome recycling factor; PFAM: ribosome recycling factor; SPTR: Ribosome-recycling factor; TIGRFAM: ribosome recycling factor; PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_004463910.1 COGs: COG0528 Uridylate kinase; InterPro IPR015963: IPR001048: IPR011817; KEGG: tmt:Tmath_1252 uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Uridylate kinase; TIGRFAM: uridylate kinase; PFAM: Amino acid kinase; TIGRFAM: uridylate kinase YP_004463911.1 COGs: COG0264 Translation elongation factor Ts; InterPro IPR001816: IPR000449: IPR014039: IPR018101; KEGG: tte:TTE1408 elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; SPTR: Elongation factor Ts; TIGRFAM: translation elongation factor Ts; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts YP_004463912.1 COGs: COG0052 Ribosomal protein S2; InterPro IPR005706: IPR001865: IPR018130; KEGG: clj:CLJU_c13020 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_004463913.1 KEGG: csc:Csac_2669 hypothetical protein; SPTR: uncharacterized protein YP_004463914.1 InterPro IPR007165; KEGG: clj:CLJU_c21840 hypothetical protein; PFAM: membrane protein of unknown function; SPTR: uncharacterized protein; PFAM: Membrane protein of unknown function YP_004463915.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018; KEGG: cth:Cthe_1282 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004463916.1 COGs: COG0177 EndoIII-related endonuclease; InterPro IPR005759: IPR003265: IPR003651: IPR004036; KEGG: bts:Btus_2551 endonuclease III; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; iron-sulfur cluster loop; SPTR: Endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: endonuclease III YP_004463917.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dhd:Dhaf_0823 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: uncharacterized protein; PFAM: Glycosyl transferases group 1 YP_004463918.1 COGs: COG2340 Uncharacterized protein with SCP/PR1 domains; InterPro IPR014258: IPR014044; KEGG: sth:STH564 hypothetical protein; PFAM: SCP-like extracellular; SPTR: uncharacterized protein; PFAM: Cysteine-rich secretory protein family; TIGRFAM: uncharacterized protein, YkwD family YP_004463919.1 KEGG: amt:Amet_2449 hypothetical protein; SPTR: uncharacterized protein YP_004463920.1 KEGG: amt:Amet_2448 hypothetical protein; SPTR: uncharacterized protein YP_004463921.1 KEGG: cac:CA_C2352 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3343) YP_004463922.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: swo:Swol_0058 glycosyltransferase-like protein; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1 YP_004463923.1 KEGG: adg:Adeg_1130 hypothetical protein; SPTR: uncharacterized protein; PFAM: TGF-beta propeptide YP_004463924.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173: IPR001440: IPR019734: IPR013026: IPR 001969; KEGG: clj:CLJU_c04550 glycosyltransferase; PFAM: glycosyl transferase 2; Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase 2; PFAM: Tetratricopeptide repeat; Glycosyl transferase 2 YP_004463925.1 KEGG: clj:CLJU_c04540 hypothetical protein; SPTR: uncharacterized protein YP_004463926.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022: IPR002627; KEGG: cth:Cthe_0775 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA) YP_004463927.1 COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); InterPro IPR014763: IPR003594: IPR013507: IPR014790: IPR 014762: IPR020667; KEGG: tte:TTE1358 DNA mismatch repair protein; PFAM: MutL dimerisation; DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; SPTR: DNA mismatch repair protein mutL; TIGRFAM: DNA mismatch repair protein MutL; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL YP_004463928.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR005748: IPR007695: IPR007860: IPR007696: IPR 007861: IPR000432; KEGG: cth:Cthe_0777 DNA mismatch repair protein MutS; PFAM: MutS III domain protein; DNA mismatch repair protein MutS domain protein; MutS II domain protein; MutS IV domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SPTR: DNA mismatch repair protein mutS; TIGRFAM: DNA mismatch repair protein MutS; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair protein MutS YP_004463929.1 COGs: COG0621 2-methylthioadenine synthetase; InterPro IPR005839: IPR006463: IPR013848: IPR007197: IPR 002792: IPR020612: IPR006638; KEGG: cth:Cthe_0783 RNA modification protein; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: RNA modification enzyme, MiaB family; TIGRFAM: tRNA-i(6)A37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family YP_004463930.1 COGs: COG1610 conserved hypothetical protein; InterPro IPR019004; KEGG: cce:Ccel_2093 GatB/YqeY domain protein; SPTR: GatB/Yqey domain protein; PFAM: Yqey-like protein YP_004463931.1 InterPro IPR001911: IPR018278; KEGG: cac:CA_C1288 30S ribosomal protein S21; PFAM: ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21 YP_004463932.1 COGs: COG0657 Esterase/lipase; KEGG: cac:CA_C2917 acetyl esterase; SPTR: Acetyl esterase enzyme; PFAM: alpha/beta hydrolase fold YP_004463933.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426: IPR000583: IPR001962: IPR017932; KEGG: mta:Moth_1299 asparagine synthase, glutamine-hydrolyzing; PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase, glutamine-hydrolyzing; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_004463934.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: tpd:Teth39_1926 ABC-3 protein; PFAM: ABC-3 protein; SPTR: ABC-3 protein; PFAM: ABC 3 transport family YP_004463935.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: tex:Teth514_0277 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004463936.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127: IPR006128: IPR006129; KEGG: tpd:Teth39_1924 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family YP_004463937.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: tpd:Teth39_1923 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family YP_004463938.1 COGs: COG3583 conserved hypothetical protein; InterPro IPR007137: IPR011098: IPR010611; KEGG: bsu:BSU00400 cell wall shaping enzyme; PFAM: 3D domain-containing protein; G5 domain protein; protein of unknown function DUF348; SPTR: uncharacterized protein; PFAM: 3D domain; Domain of unknown function (DUF348); G5 domain YP_004463939.1 COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); InterPro IPR011530: IPR001737: IPR020596: IPR020598; KEGG: cdl:CDR20291_3360 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; PRIAM: rRNA (adenine-N(6)-)-methyltransferase; SMART: Ribosomal RNA adenine methylase transferase-like; SPTR: Ribosomal RNA small subunit methyltransferase A; TIGRFAM: dimethyladenosine transferase; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_004463940.1 KEGG: rca:Rcas_4360 cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein YP_004463941.1 COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: pth:PTH_1959 ABC-type Co2+ transport system, permease component; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: ABC-type Co2+ transport system, permease component; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM YP_004463942.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase 4 of glycosyl hydrolase; InterPro IPR001088: IPR019802; KEGG: hor:Hore_23300 glycoside hydrolase 4; PFAM: glycoside hydrolase 4; SPTR: Glycoside hydrolase 4; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004463943.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060: IPR018062: IPR020449; KEGG: hor:Hore_23290 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Msm operon regulatory protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain YP_004463944.1 COGs: COG2217 Cation transport ATPase; InterPro IPR006404: IPR006416: IPR001757: IPR006121: IPR 008250: IPR005834: IPR018303: IPR001366; KEGG: aoe:Clos_1087 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Cadmium-translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004463945.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155: IPR001327: IPR013027: IPR000103; KEGG: tte:TTE2131 NADH:flavin oxidoreductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase YP_004463946.1 COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); InterPro IPR006316: IPR001926: IPR006653; KEGG: pth:PTH_0608 tryptophan synthase subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Predicted alternative tryptophan synthase beta-subunit; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme YP_004463947.1 COGs: COG1615 conserved hypothetical protein; InterPro IPR005372: IPR018247; KEGG: tit:Thit_0030 protein of unknown function UPF0182; PFAM: protein of unknown function UPF0182; SPTR: UPF0182 protein TtheDRAFT_2455; PFAM: Uncharacterised protein family (UPF0182) YP_004463948.1 SPTR: Regulatory protein, LuxR YP_004463949.1 InterPro IPR013838; KEGG: rci:RCIX1583 hypothetical protein; SPTR: uncharacterized protein YP_004463950.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: tme:Tmel_0007 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004463951.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: tit:Thit_2149 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase YP_004463952.1 COGs: COG4769 membrane protein; InterPro IPR010898: IPR014535; KEGG: amt:Amet_4332 heptaprenyl diphosphate synthase component I; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Heptaprenyl diphosphate synthase component I; PFAM: Heptaprenyl diphosphate synthase component I YP_004463953.1 COGs: COG5341 conserved hypothetical protein; InterPro IPR010739; KEGG: ckr:CKR_2733 hypothetical protein; PFAM: protein of unknown function DUF1312; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1312) YP_004463954.1 COGs: COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; InterPro IPR003374; KEGG: cbi:CLJ_B0433 ApbE family protein; PFAM: ApbE family lipoprotein; SPTR: ApbE family protein; PFAM: ApbE family YP_004463955.1 COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: cth:Cthe_0560 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004463956.1 COGs: COG1453 oxidoreductase of the aldo/keto reductase; InterPro IPR001395; KEGG: dth:DICTH_0598 oxidoreductase, PFAM: aldo/keto reductase; SPTR: Oxidoreductase, ; PFAM: Aldo/keto reductase YP_004463957.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611; KEGG: tau:Tola_0048 PfkB domain protein; PFAM: PfkB domain protein; SPTR: Kinase, PfkB family; PFAM: pfkB family carbohydrate kinase YP_004463958.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: cth:Cthe_1959 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain YP_004463959.1 COGs: COG3459 Cellobiose phosphorylase; InterPro IPR009342: IPR010383: IPR010403; KEGG: chl:Chy400_4165 glycosyltransferase 36; PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; SPTR: Glycosyltransferase 36; PFAM: Glycosyltransferase 36; carbohydrate binding domain; Glycosyltransferase 36 associated family YP_004463960.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: gym:GYMC10_3167 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI-family regulatory protein; manually curated; PFAM: Bacterial regulatory proteins, lacI family; family YP_004463961.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_1293 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004463962.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4741 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463963.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4742 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004463964.1 KEGG: tte:TTE1621 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3189) YP_004463965.1 KEGG: swo:Swol_1336 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF3189) YP_004463966.1 InterPro IPR010897; KEGG: aoe:Clos_1395 stage II sporulation P family protein; PFAM: Stage II sporulation P family protein; SPTR: Stage II sporulation P family protein; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation protein P (SpoIIP); TIGRFAM: stage II sporulation protein P YP_004463967.1 InterPro IPR011672; KEGG: amt:Amet_2864 hypothetical protein; PFAM: protein of unknown function DUF1614; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1614) YP_004463968.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR005672: IPR000515; KEGG: tpd:Teth39_0829 phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstA YP_004463969.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864: IPR000515; KEGG: tpd:Teth39_0828 phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstC; phosphate ABC transporter, permease PstA YP_004463970.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660: IPR004089; KEGG: tex:Teth514_0389 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004463971.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862: IPR006059; KEGG: tpd:Teth39_0827 phosphate binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Phosphate binding protein; TIGRFAM: phosphate binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate binding protein YP_004463972.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR005990: IPR001093: IPR000644: IPR015875: IPR 018529; KEGG: tte:TTE0582 IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: Inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_004463973.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: mta:Moth_0421 ROK; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: HTH domain; ROK family YP_004463974.1 COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611: IPR002173; KEGG: tte:TTE0768 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; PFAM: PfkB domain protein; SPTR: ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I YP_004463975.1 KEGG: tte:TTE0767 hypothetical protein; SPTR: uncharacterized protein YP_004463976.1 InterPro IPR005834; KEGG: tte:TTE0766 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; PFAM: haloacid dehalogenase-like hydrolase YP_004463977.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: cpy:Cphy_1651 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004463978.1 COGs: COG3467 flavin-nucleotide-binding protein; InterPro IPR011576; KEGG: cbl:CLK_0422 nitroimidazole resistance protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: nitroimidazole resistance protein NimA; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004463979.1 KEGG: npu:Npun_F2880 hypothetical protein; SPTR: uncharacterized protein YP_004463980.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR006407: IPR004193: IPR006047: IPR006048: IPR 006589; KEGG: cbt:CLH_3167 glycogen branching enzyme; PFAM: alpha amylase all-beta; glycoside hydrolase 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: 1,4-alpha-glucan-branching enzyme; TIGRFAM: 1,4-alpha-glucan branching enzyme; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase YP_004463981.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR011832; KEGG: ckr:CKR_3081 hypothetical protein; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: uncharacterized protein; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit YP_004463982.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR011831: IPR005835: IPR005836; KEGG: ckr:CKR_3082 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate adenylyltransferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase YP_004463983.1 COGs: COG0366 Glycosidase; InterPro IPR006047: IPR006589; KEGG: ckr:CKR_3083 hypothetical protein; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: uncharacterized protein; PFAM: Alpha amylase, catalytic domain YP_004463984.1 COGs: COG0058 Glucan phosphorylase; InterPro IPR011833: IPR000811; KEGG: cpr:CPR_0083 glycogen phosphorylase; PFAM: glycosyl transferase 35; SPTR: Phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases YP_004463985.1 COGs: COG0297 Glycogen synthase; InterPro IPR011835: IPR013534: IPR001296; KEGG: cpr:CPR_0082 glycogen synthase; PFAM: Starch synthase catalytic domain-containing protein; glycosyl transferase group 1; PRIAM: Starch synthase; SPTR: Glycogen synthase; TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type YP_004463986.1 COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: tpd:Teth39_1751 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004463987.1 COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR006221: IPR000991: IPR017926: IPR006220: IPR 011702: IPR001317; KEGG: tjr:TherJR_1606 glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; SPTR: Glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004463988.1 KEGG: bhy:BHWA1_01155 hypothetical protein; SPTR: uncharacterized protein; PFAM: Rubrerythrin YP_004463989.1 COGs: COG1659 conserved hypothetical protein; InterPro IPR007544; KEGG: aae:aq_1760 hypothetical protein; PFAM: Linocin_M18 bacteriocin protein; SPTR: uncharacterized protein; PFAM: Encapsulating protein for peroxidase YP_004463990.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR020904: IPR002347; KEGG: clj:CLJU_c29220 short-chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short chain dehydrogenase/reductase; PFAM: short chain dehydrogenase YP_004463991.1 COGs: COG2866 carboxypeptidase; InterPro IPR000834; KEGG: cbb:CLD_3164 zinc carboxypeptidase; PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; SPTR: Zinc carboxypeptidase; PFAM: Zinc carboxypeptidase YP_004463992.1 COGs: COG1633 conserved hypothetical protein; InterPro IPR003251; KEGG: tjr:TherJR_1045 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin; PFAM: Rubrerythrin; Domain of unknown function (DUF2383) YP_004463993.1 KEGG: tte:TTE0521 hypothetical protein; SPTR: uncharacterized protein YP_004463994.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: oih:OB0844 dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004463995.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460; KEGG: cbl:CLK_2815 penicillin-binding protein; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; SPTR: Penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain YP_004463996.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: amt:Amet_0334 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein YP_004463997.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: tjr:TherJR_1791 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: FHA domain containing protein; PFAM: FHA domain YP_004463998.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dae:Dtox_0715 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sporulation initiation phosphotransferase F; PFAM: Response regulator receiver domain YP_004463999.1 InterPro IPR003675; KEGG: aoe:Clos_2014 abortive infection protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein; PFAM: CAAX amino terminal protease YP_004464000.1 COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR002292: IPR006132: IPR006131: IPR006130; KEGG: drm:Dred_0276 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; PRIAM: Ornithine carbamoyltransferase; SPTR: Ornithine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_004464001.1 InterPro IPR000182; KEGG: csc:Csac_1563 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004464002.1 KEGG: sus:Acid_6615 hypothetical protein; SPTR: uncharacterized protein YP_004464003.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002052: IPR002296; KEGG: pmo:Pmob_1273 hypothetical protein; SPTR: uncharacterized protein; PFAM: N-6 DNA Methylase YP_004464004.1 COGs: COG3345 Alpha-galactosidase; InterPro IPR008811; KEGG: pjd:Pjdr2_2568 raffinose synthase; PFAM: raffinose synthase; SPTR: Raffinose synthase; PFAM: Raffinose synthase or seed inhibition protein Sip1 YP_004464005.1 COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: cth:Cthe_2393 thiamine pyrophosphate enzyme-like TPP-binding; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate enzyme-like TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004464006.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: csc:Csac_1460 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain YP_004464007.1 COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898: IPR017896: IPR017900; KEGG: cth:Cthe_2391 pyruvate ferredoxin oxidoreductase, delta subunit; SPTR: Pyruvate synthase subunit porD; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family YP_004464008.1 COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR011894: IPR019752; KEGG: cth:Cthe_2390 pyruvate ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate ferredoxin oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family YP_004464009.1 COGs: COG0514 Superfamily II DNA helicase; InterPro IPR018329: IPR011545: IPR001650: IPR014021: IPR 014001; KEGG: caa:Caka_2440 ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family YP_004464010.1 COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: rci:RCIX1907 hypothetical protein; PFAM: protein of unknown function UPF0047; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme YP_004464011.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: ses:SARI_03137 hypothetical protein; PFAM: sulfatase; SPTR: arylsulfatase; PFAM: Sulfatase YP_004464012.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_0956 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464013.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_0957 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464014.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_0958 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464015.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ckr:CKR_2700 hypothetical protein; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family YP_004464016.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: pjd:Pjdr2_4150 sulfatase; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004464017.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: oih:OB1195 hypothetical protein; SPTR: Hypothetical conserved protein; PFAM: Prolyl oligopeptidase YP_004464018.1 InterPro IPR004370; KEGG: chy:CHY_0887 4-oxalocrotonate tautomerase; PFAM: 4-oxalocrotonate tautomerase; SPTR: 4-oxalocrotonate tautomerase; PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase enzyme YP_004464019.1 COGs: COG0279 Phosphoheptose isomerase; InterPro IPR001347; KEGG: tte:TTE0762 phosphoheptose isomerase; PFAM: sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: SIS domain YP_004464020.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tte:TTE0761 transcriptional regulator; PFAM: ROK family protein; SPTR: Transcriptional regulator; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004464021.1 COGs: COG0383 Alpha-mannosidase; InterPro IPR000602: IPR015341: IPR011682; KEGG: ttr:Tter_1503 glycoside hydrolase 38; PFAM: glycoside hydrolase 38; Glycoside hydrolase 38 central region; glycosyl hydrolase 38 domain protein; SPTR: Glycoside hydrolase 38; PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain; Alpha mannosidase, middle domain YP_004464022.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104: IPR006102: IPR006103; KEGG: hor:Hore_13110 beta-mannosidase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 2 TIM barrel; SPTR: Beta-mannosidase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain YP_004464023.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR006000: IPR018484: IPR018485; KEGG: aac:Aaci_2179 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase YP_004464024.1 InterPro IPR006992; KEGG: sai:Saci_2142 hypothetical protein; PFAM: amidohydrolase 2; SPTR: Predicted protein; PFAM: Amidohydrolase YP_004464025.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ppp:PHYPADRAFT_102740 hypothetical protein; PFAM: extracellular solute-binding protein family 1; SPTR: Predicted protein; PFAM: Bacterial extracellular solute-binding protein YP_004464026.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: bcl:ABC3213 sugar ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464027.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: bcl:ABC3214 sugar ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464028.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: mta:Moth_2024 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004464029.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772; KEGG: cce:Ccel_0203 glycoside hydrolase 3 domain protein; PFAM: glycoside hydrolase 3 domain protein; SPTR: Beta-xylosidase B; PFAM: Glycosyl hydrolase 3 C terminal domain; Glycosyl hydrolase 3 N terminal domain YP_004464030.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034: IPR014036: IPR001845: IPR018356; KEGG: csc:Csac_0347 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004464031.1 COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: chy:CHY_1258 hypothetical protein; PFAM: type III effector Hrp-dependent outers; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF1537 YP_004464032.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: adg:Adeg_0056 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: 5-dehydro-2-deoxyphosphogluconate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004464033.1 InterPro IPR015942; KEGG: ppp:PHYPADRAFT_104124 hypothetical protein; PFAM: Asp/Glu/hydantoin racemase; SPTR: Predicted protein; PFAM: Asp/Glu/Hydantoin racemase YP_004464034.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ttr:Tter_2216 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464035.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: tra:Trad_2442 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464036.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tra:Trad_2441 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004464037.1 KEGG: ate:Athe_2559 hypothetical protein; SPTR: uncharacterized protein YP_004464038.1 COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR018170: IPR020471; KEGG: bbe:BBR47_42050 probable 2,5-diketo-D-gluconic acid reductase; PFAM: aldo/keto reductase; PRIAM: Methylglyoxal reductase (NADPH-dependent); SPTR: Probable 2,5-diketo-D-gluconic acid reductase; PFAM: Aldo/keto reductase YP_004464039.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: cno:NT01CX_1620 aminopeptidase; PFAM: peptidase M29 aminopeptidase II; SPTR: Peptidase M29 aminopeptidase II; PFAM: Thermophilic metalloprotease (M29) YP_004464040.1 InterPro IPR018392: IPR002482; KEGG: aoe:Clos_1944 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; PFAM: LysM domain YP_004464041.1 COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: cno:NT01CX_0248 thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004464042.1 KEGG: ant:Arnit_3051 hypothetical protein; SPTR: uncharacterized protein YP_004464043.1 COGs: COG2145 Hydroxyethylthiazole kinase sugar kinase; InterPro IPR000417: IPR011144; KEGG: tex:Teth514_0567 hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase; PRIAM: Hydroxyethylthiazole kinase; SPTR: Hydroxyethylthiazole kinase; PFAM: Hydroxyethylthiazole kinase; TIGRFAM: hydroxyethylthiazole kinase YP_004464044.1 COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: dhd:Dhaf_2518 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC YP_004464045.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249: IPR000838; KEGG: tjr:TherJR_0483 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004464046.1 KEGG: bph:Bphy_0910 transmembrane anti-sigma factor; SPTR: uncharacterized protein YP_004464047.1 KEGG: pjd:Pjdr2_1704 hypothetical protein; SPTR: uncharacterized protein YP_004464048.1 COGs: COG1238 membrane protein; InterPro IPR015414; KEGG: drm:Dred_2300 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004464049.1 KEGG: cce:Ccel_1466 hypothetical protein; SPTR: Membrane protein YP_004464050.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR019734: IPR013026; KEGG: cbl:CLK_3368 DnaJ family molecular chaperone; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Molecular chaperone, DnaJ family; PFAM: DnaJ domain YP_004464051.1 COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR006115: IPR003421; KEGG: tte:TTE0923 NAD/NADP octopine/nopaline dehydrogenas; PFAM: NAD/NADP octopine/nopaline dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; SPTR: NAD/NADP octopine/nopaline dehydrogenas; PFAM: NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YP_004464052.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524: IPR011663; KEGG: bld:BLi04350 YvoA; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator (GntR family) YvoA; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004464053.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: pjd:Pjdr2_0342 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: AP endonuclease, family 2; PFAM: Xylose isomerase-like TIM barrel YP_004464054.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: gym:GYMC10_4655 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase, NAD-binding Rossmann fold protein; PFAM: Oxidoreductase, C-terminal alpha/beta domain; Oxidoreductase, NAD-binding Rossmann fold YP_004464055.1 COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018322: IPR006148: IPR018321; KEGG: tte:TTE1023 glucosamine-6-phosphate deaminase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: Glucosamine-6-phosphate isomerase; TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase YP_004464056.1 KEGG: cce:Ccel_1549 outer membrane protein; SPTR: uncharacterized protein YP_004464057.1 COGs: COG2033 Desulfoferrodoxin; InterPro IPR004462: IPR004793: IPR002742; KEGG: dma:DMR_17610 desulfoferrodoxin; PFAM: Desulfoferrodoxin ferrous iron-binding region; Desulfoferrodoxin Dfx domain protein; SPTR: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin; PFAM: Desulfoferrodoxin, N-terminal domain; Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain YP_004464058.1 COGs: COG1592 Rubrerythrin; InterPro IPR003251: IPR004039: IPR009040; KEGG: csc:Csac_2430 rubrerythrin; PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubrerythrin; PFAM: Rubrerythrin YP_004464059.1 COGs: COG1874 Beta-galactosidase; InterPro IPR013529: IPR013738: IPR013739: IPR003476; KEGG: gyc:GYMC61_0530 beta-galactosidase; PFAM: Glycoside hydrolase 42 domain protein; Beta-galactosidase trimerisation domain protein; Beta-galactosidase domain protein; PRIAM: Beta-galactosidase; SPTR: Beta-galactosidase; PFAM: Beta-galactosidase trimerisation domain; Beta-galactosidase C-terminal domain; Beta-galactosidase YP_004464060.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: tte:TTE1951 dehydrogenase and related proteins; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, C-terminal alpha/beta domain; Oxidoreductase, NAD-binding Rossmann fold YP_004464061.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772; KEGG: dth:DICTH_0696 xylosidase/arabinosidase; PFAM: glycoside hydrolase 3 domain protein; SPTR: Xylosidase/arabinosidase; PFAM: Glycosyl hydrolase 3 C terminal domain; Glycosyl hydrolase 3 N terminal domain YP_004464062.1 KEGG: clj:CLJU_c38670 penicillin-binding protein; SPTR: NADH-ubiquinone oxidoreductase chain 2 YP_004464063.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR010066: IPR003439: IPR013563: IPR017871: IPR 003593; KEGG: sth:STH296 oligoeptide ABC transporter ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligoeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004464064.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR010066: IPR003439: IPR013563: IPR003593; KEGG: sth:STH297 ABC transporter ATP binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: ABC transporter ATP binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004464065.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: sth:STH298 oligopeptide ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464066.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: sth:STH299 oligopeptide ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464067.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005: IPR018060: IPR020449; KEGG: gym:GYMC10_2461 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464068.1 InterPro IPR018126; KEGG: tpd:Teth39_0186 hypothetical protein; SPTR: uncharacterized protein; PFAM: Small, acid-soluble spore proteins, alpha/beta type YP_004464069.1 InterPro IPR014239: IPR005075; KEGG: tpd:Teth39_0185 peptidase; PFAM: Propeptide PepSY amd peptidase M4; SPTR: Germination protein YpeB; TIGRFAM: germination protein YpeB; TIGRFAM: germination protein YpeB YP_004464070.1 COGs: COG3773 Cell wall hydrolyses involved in spore germination; InterPro IPR014224: IPR002477: IPR011105; KEGG: clj:CLJU_c02980 spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein; SPTR: uncharacterized protein; TIGRFAM: spore cortex-lytic enzyme; PFAM: peptidoglycan binding domain; Cell Wall Hydrolase; TIGRFAM: spore cortex-lytic enzyme YP_004464071.1 KEGG: cth:Cthe_1153 diguanylate cyclase; SPTR: M protein YP_004464072.1 COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310: IPR008286; KEGG: csc:Csac_1361 Orn/Lys/Arg decarboxylase, major region; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; SPTR: Orn/Lys/Arg decarboxylase major region; PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain YP_004464073.1 InterPro IPR014202; KEGG: aoe:Clos_0291 sporulation stage II protein R; PFAM: Sporulation stage II protein R; SPTR: Sporulation stage II protein R; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R YP_004464074.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: hor:Hore_12950 uroporphyrinogen-III decarboxylase; SPTR: Uroporphyrinogen-III decarboxylase; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464075.1 KEGG: tmt:Tmath_2131 molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; PFAM: Uncharacterized protein family UPF0007 YP_004464076.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; InterPro IPR004424: IPR006204: IPR013750; KEGG: clj:CLJU_c02110 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004464077.1 InterPro IPR005502: IPR018247; KEGG: gym:GYMC10_4315 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: uncharacterized protein; PFAM: ADP-ribosylglycohydrolase YP_004464078.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341: IPR013342: IPR022272: IPR018110; KEGG: pjd:Pjdr2_0782 galactonate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain YP_004464079.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ttr:Tter_2528 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464080.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_0779 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type sugar transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464081.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059: IPR022272; KEGG: pjd:Pjdr2_0778 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein, family 1 YP_004464082.1 KEGG: bcv:Bcav_0914 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1083) YP_004464083.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060: IPR018062: IPR020449; KEGG: cce:Ccel_0142 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464084.1 InterPro IPR013096; KEGG: hvo:HVO_B0224 cupin; PFAM: Cupin 2 conserved barrel domain protein; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004464085.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bse:Bsel_3293 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase YP_004464086.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csc:Csac_0299 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464087.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: csc:Csac_0298 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464088.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: csc:Csac_0297 ABC-type sugar transport system periplasmic component-like protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transport system periplasmic component-like protein; PFAM: Bacterial extracellular solute-binding protein YP_004464089.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003660: IPR010559: IPR003594; KEGG: csc:Csac_2533 integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464090.1 KEGG: csc:Csac_0666 hypothetical protein; SPTR: uncharacterized protein YP_004464091.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR000005: IPR018060: IPR018062: IPR 020449; KEGG: clo:HMPREF0868_0308 response regulator receiver domain protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464092.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR020904: IPR002347; KEGG: pjd:Pjdr2_4221 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004464093.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR002347; KEGG: pjd:Pjdr2_4220 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004464094.1 COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: pjd:Pjdr2_2154 N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) YP_004464095.1 COGs: COG0684 Demethylmenaquinone methyltransferase; KEGG: pjd:Pjdr2_4223 demethylmenaquinone methyltransferase-like protein; SPTR: Demethylmenaquinone methyltransferase-like protein; PFAM: Demethylmenaquinone methyltransferase YP_004464096.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341; KEGG: pjd:Pjdr2_4222 mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain YP_004464097.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_2006 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type sugar transport system, permease component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464098.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_2005 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464099.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_3412 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464100.1 COGs: COG2730 Endoglucanase; InterPro IPR001547; KEGG: dth:DICTH_0508 endoglucanase; PFAM: glycoside hydrolase 5; SPTR: Endoglucanase; PFAM: Cellulase (glycosyl hydrolase 5) YP_004464101.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: csc:Csac_2529 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein, family 1 YP_004464102.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csc:Csac_2530 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464103.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: csc:Csac_2531 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464104.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: tte:TTE0053 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004464105.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: dds:Ddes_1981 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase (NAD+); PFAM: Aldehyde dehydrogenase YP_004464106.1 KEGG: fnu:FN1309 hypothetical protein; SPTR: uncharacterized protein YP_004464107.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863: IPR000871; KEGG: tit:Thit_1492 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase M16) YP_004464108.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR007863; KEGG: cth:Cthe_0986 peptidase M16-like protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16-like protein; PFAM: Peptidase M16 inactive domain YP_004464109.1 InterPro IPR014247: IPR019076; KEGG: tpd:Teth39_0801 hypothetical protein; PFAM: Sporulation lipoprotein YhcN/YlaJ-like; SPTR: uncharacterized protein; TIGRFAM: sporulation lipoprotein, YhcN/YlaJ family; PFAM: Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); TIGRFAM: sporulation lipoprotein, YhcN/YlaJ family YP_004464110.1 KEGG: tjr:TherJR_2317 hypothetical protein; SPTR: uncharacterized protein YP_004464111.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: cpy:Cphy_3881 flavin reductase domain-containing protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavin reductase domain protein FMN-binding; PFAM: Flavin reductase like domain YP_004464112.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fpl:Ferp_0944 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase YP_004464113.1 COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: tpd:Teth39_1971 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase YP_004464114.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR013247: IPR002508: IPR003646; KEGG: bmq:BMQ_0201 SH3 domain protein; PFAM: cell wall hydrolase/autolysin; SH3 type 3 domain protein; SMART: cell wall hydrolase/autolysin; SH3 domain protein; SPTR: SH3 domain protein; PFAM: N-acetylmuramoyl-L-alanine amidase; Bacterial SH3 domain YP_004464115.1 COGs: COG3773 Cell wall hydrolyses involved in spore germination; InterPro IPR002477: IPR011105; KEGG: dhd:Dhaf_4849 spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein; SPTR: uncharacterized protein; PFAM: peptidoglycan binding domain; Cell Wall Hydrolase; TIGRFAM: spore cortex-lytic enzyme YP_004464116.1 COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406: IPR020097; KEGG: cth:Cthe_2939 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_004464117.1 COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: tte:TTE2259 ABC-type cobalt transport system, permease component CbiQ and related transporters; PFAM: cobalt transport protein; SPTR: ABC-type cobalt transport system, permease component CbiQ and related transporters; PFAM: Cobalt transport protein YP_004464118.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439: IPR015856: IPR017871: IPR003593; KEGG: aoe:Clos_0524 cobalt transporter ATP-binding subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal; TIGRFAM: cobalt transport protein ATP-binding subunit YP_004464119.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439: IPR015856: IPR017871: IPR003593; KEGG: aoe:Clos_0523 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal; TIGRFAM: cobalt transport protein ATP-binding subunit YP_004464120.1 COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: ere:EUBREC_0446 50S ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_004464121.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterPro IPR011773: IPR011260: IPR011261: IPR011262: IPR 011263; KEGG: cth:Cthe_2932 DNA-directed RNA polymerase subunit alpha; PFAM: RNA polymerase insert; RNA polymerase dimerisation; RNA polymerase alpha subunit domain protein; SMART: RNA polymerase RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type YP_004464122.1 COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR005709: IPR001912: IPR002942: IPR018079; KEGG: pth:PTH_0347 30S ribosomal protein S4; PFAM: RNA-binding S4 domain protein; ribosomal protein S4; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4; PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type YP_004464123.1 COGs: COG0100 Ribosomal protein S11; InterPro IPR019981: IPR001971: IPR018102; KEGG: tmt:Tmath_1907 30S ribosomal protein S11; PFAM: ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; PFAM: Ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11 YP_004464124.1 COGs: COG0099 Ribosomal protein S13; InterPro IPR019980: IPR001892: IPR018269; KEGG: chy:CHY_2284 30S ribosomal protein S13; PFAM: ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: 30S ribosomal protein S13; PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13 YP_004464125.1 InterPro IPR000473; KEGG: dhd:Dhaf_0446 50S ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_004464126.1 COGs: COG0361 Translation initiation factor 1 (IF-1); InterPro IPR004368: IPR006196; KEGG: tmt:Tmath_1910 translation initiation factor IF-1; PFAM: S1 IF1 family protein; SPTR: Translation initiation factor IF-1; TIGRFAM: translation initiation factor IF-1; PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_004464127.1 KEGG: tit:Thit_1950 hypothetical protein; SPTR: uncharacterized protein YP_004464128.1 COGs: COG0024 Methionine aminopeptidase; InterPro IPR002467: IPR000994: IPR001714; KEGG: ckr:CKR_0205 hypothetical protein; PFAM: peptidase M24; PRIAM: Methionyl aminopeptidase; SPTR: Methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; PFAM: Metallopeptidase M24; TIGRFAM: methionine aminopeptidase, type I YP_004464129.1 COGs: COG0563 Adenylate kinase and related kinase; InterPro IPR006259: IPR000850: IPR007862; KEGG: adg:Adeg_1237 adenylate kinase; PFAM: adenylate kinase; adenylate kinase lid domain-containing protein; SPTR: Adenylate kinase; TIGRFAM: adenylate kinase; PFAM: Adenylate kinase, active site lid; Adenylate kinase; TIGRFAM: adenylate kinases YP_004464130.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208; KEGG: hmo:HM1_1398 preprotein translocase subunit SecY; PFAM: SecY protein; SPTR: Preprotein translocase subunit secY; TIGRFAM: preprotein translocase, SecY subunit; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit YP_004464131.1 COGs: COG0200 Ribosomal protein L15; InterPro IPR005749: IPR001196; KEGG: tte:TTE2273 ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: ribosomal protein L15; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_004464132.1 InterPro IPR005996: IPR000517: IPR018038; KEGG: kra:Krad_0706 ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_004464133.1 COGs: COG0098 Ribosomal protein S5; InterPro IPR005712: IPR013810: IPR005324: IPR018192; KEGG: cce:Ccel_0775 30S ribosomal protein S5; PFAM: Ribosomal protein S5; ribosomal protein S5 domain protein; SPTR: Ribosomal protein S5; TIGRFAM: ribosomal protein S5; PFAM: Ribosomal protein S5, N-terminal domain; Ribosomal protein S5, C-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_004464134.1 COGs: COG0256 Ribosomal protein L18; InterPro IPR004389: IPR005484; KEGG: tte:TTE2275 50S ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; SPTR: 50S ribosomal protein L18; TIGRFAM: ribosomal protein L18; PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_004464135.1 COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR019906: IPR020040: IPR010916: IPR000702; KEGG: cbk:CLL_A0253 50S ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: ribosomal protein L6; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type YP_004464136.1 COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: csc:Csac_2273 30S ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: 30S ribosomal protein S8; PFAM: Ribosomal protein S8 YP_004464137.1 COGs: COG0199 Ribosomal protein S14; InterPro IPR001209; KEGG: cce:Ccel_0771 30S ribosomal protein S14; PFAM: ribosomal protein S14; SPTR: uncharacterized protein; PFAM: Ribosomal protein S14p/S29e YP_004464138.1 COGs: COG0094 Ribosomal protein L5; InterPro IPR020929: IPR002132; KEGG: dsy:DSY0483 50S ribosomal protein L5; SPTR: 50S ribosomal protein L5; PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5 YP_004464139.1 COGs: COG0198 Ribosomal protein L24; InterPro IPR003256: IPR005824: IPR005825; KEGG: cbf:CLI_3652 50S ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle YP_004464140.1 COGs: COG0093 Ribosomal protein L14; InterPro IPR005745: IPR000218: IPR019972; KEGG: tte:TTE2282 ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: ribosomal protein L14; PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_004464141.1 COGs: COG0186 Ribosomal protein S17; InterPro IPR019984: IPR000266: IPR019979; KEGG: csc:Csac_2278 30S ribosomal protein S17; PFAM: ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17; PFAM: Ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17 YP_004464142.1 COGs: COG0255 Ribosomal protein L29; InterPro IPR001854: IPR018254; KEGG: tjr:TherJR_0304 ribosomal protein L29; PFAM: ribosomal protein L29; SPTR: Ribosomal protein L29; TIGRFAM: ribosomal protein L29; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_004464143.1 COGs: COG0197 Ribosomal protein L16/L10E; InterPro IPR000114: IPR016180: IPR020798; KEGG: cth:Cthe_2910 50S ribosomal protein L16; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: ribosomal protein L16; manually curated; PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_004464144.1 COGs: COG0092 Ribosomal protein S3; InterPro IPR005704: IPR008282: IPR004044: IPR001351: IPR 018280: IPR004087; KEGG: cce:Ccel_0764 ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; Ribosomal protein S3 domain; KH type 2 domain protein; SMART: KH domain protein; SPTR: Ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: KH domain; Ribosomal protein S3, C-terminal domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type; ribosomal protein S3, eukaryotic/archaeal type YP_004464145.1 COGs: COG0091 Ribosomal protein L22; InterPro IPR005727: IPR001063: IPR018260; KEGG: aac:Aaci_2706 ribosomal protein L22; PFAM: ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: ribosomal protein L22; PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_004464146.1 COGs: COG0185 Ribosomal protein S19; InterPro IPR002222: IPR020934: IPR005732; KEGG: nth:Nther_0198 SSU ribosomal protein S19P; PFAM: ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: ribosomal protein S19; PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_004464147.1 COGs: COG0090 Ribosomal protein L2; InterPro IPR002171: IPR005880; KEGG: tte:TTE2290 50S ribosomal protein L2; PFAM: ribosomal protein L2; SPTR: 50S ribosomal protein L2; TIGRFAM: ribosomal protein L2; PFAM: Ribosomal Proteins L2, RNA binding domain; Ribosomal Proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar YP_004464148.1 COGs: COG0089 Ribosomal protein L23; InterPro IPR013025: IPR001014; KEGG: amt:Amet_4476 50S ribosomal protein L23; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; PFAM: Ribosomal protein L23 YP_004464149.1 COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: aoe:Clos_0493 50S ribosomal protein L4; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1 family YP_004464150.1 COGs: COG0087 Ribosomal protein L3; InterPro IPR000597: IPR019926: IPR019927; KEGG: tpd:Teth39_0374 50S ribosomal protein L3; PFAM: ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3; PFAM: Ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial YP_004464151.1 COGs: COG0051 Ribosomal protein S10; InterPro IPR001848: IPR018268: IPR005731; KEGG: cth:Cthe_2902 30S ribosomal protein S10; PFAM: ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: ribosomal protein S10; PFAM: Ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10(archaeal)/S20(eukaryotic); ribosomal protein S10, bacterial/organelle YP_004464152.1 COGs: COG0050 GTPase - translation elongation factors; InterPro IPR000795: IPR004161: IPR004160: IPR004541: IPR 005225; KEGG: bts:Btus_0151 translation elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain-containing protein; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004464153.1 COGs: COG0480 Translation elongation factors (GTPase); InterPro IPR000795: IPR004161: IPR005517: IPR000640: IPR 004540: IPR005225; KEGG: ate:Athe_0809 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Elongation factor G; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004464154.1 COGs: COG0049 Ribosomal protein S7; InterPro IPR000235: IPR005717; KEGG: tit:Thit_1979 ribosomal protein S7; PFAM: ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: ribosomal protein S7; PFAM: Ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle YP_004464155.1 COGs: COG0048 Ribosomal protein S12; InterPro IPR006032: IPR005679; KEGG: afn:Acfer_1934 ribosomal protein S12; PFAM: ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: ribosomal protein S12; PFAM: Ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle YP_004464156.1 InterPro IPR004038: IPR000948; KEGG: sth:STH3081 ribosomal protein L7AE family protein; PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: Ribosomal protein L7AE family; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family YP_004464157.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; InterPro IPR007080: IPR000722: IPR007066: IPR007083: IPR 007081: IPR006592: IPR012754; KEGG: cth:Cthe_2725 DNA-directed RNA polymerase subunit beta'; PFAM: RNA polymerase Rpb1 domain 1; RNA polymerase alpha subunit; RNA polymerase Rpb1 domain 3; RNA polymerase Rpb1 domain 4; RNA polymerase Rpb1 domain 5; SMART: RNA polymerase I subunit A domain protein; SPTR: DNA-directed RNA polymerase, beta' subunit; TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form YP_004464158.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterPro IPR007644: IPR007642: IPR007645: IPR019462: IPR 007120: IPR007641: IPR007121: IPR010243; KEGG: cth:Cthe_2724 DNA-directed RNA polymerase subunit beta; PFAM: RNA polymerase Rpb2 domain 6; RNA polymerase beta subunit; RNA polymerase Rpb2 domain 2; RNA polymerase Rpb2 domain 3; DNA-directed RNA polymerase, beta subunit, external 1 domain; RNA polymerase Rpb2 domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit YP_004464159.1 COGs: COG0222 Ribosomal protein L7/L12; InterPro IPR013823: IPR000206; KEGG: tex:Teth514_0858 50S ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_004464160.1 COGs: COG0244 Ribosomal protein L10; InterPro IPR001790: IPR002363; KEGG: tit:Thit_1985 ribosomal protein L10; PFAM: ribosomal protein L10; SPTR: Ribosomal protein L10; PFAM: Ribosomal protein L10 YP_004464161.1 COGs: COG0081 Ribosomal protein L1; InterPro IPR002143: IPR005878; KEGG: tex:Teth514_0856 50S ribosomal protein L1; PFAM: ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: ribosomal protein L1; PFAM: Ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast YP_004464162.1 COGs: COG0080 Ribosomal protein L11; InterPro IPR020784: IPR020783: IPR000911: IPR006519; KEGG: cth:Cthe_2720 50S ribosomal protein L11; PFAM: Ribosomal protein L11-like; SMART: ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_004464163.1 COGs: COG0250 Transcription antiterminator; InterPro IPR006645: IPR005824: IPR001062: IPR015869; KEGG: cce:Ccel_0307 NusG antitermination factor; PFAM: NGN domain-containing protein; KOW domain protein; SMART: NGN domain-containing protein; KOW domain protein; SPTR: Transcription antitermination protein nusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: Transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG YP_004464164.1 InterPro IPR001901: IPR005807; KEGG: gwc:GWCH70_0096 preprotein translocase subunit SecE; PFAM: protein secE/sec61-gamma protein; SPTR: Preprotein translocase, SecE subunit; TIGRFAM: preprotein translocase, SecE subunit; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_004464165.1 COGs: COG0267 Ribosomal protein L33; InterPro IPR001705: IPR018264; KEGG: cth:Cthe_2717 50S ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004464166.1 COGs: COG0050 GTPase - translation elongation factors; InterPro IPR000795: IPR004161: IPR004160: IPR004541: IPR 005225; KEGG: bts:Btus_0151 translation elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain-containing protein; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004464167.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR000943: IPR016371: IPR 014284; KEGG: tpd:Teth39_0357 RNA polymerase factor sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-H factor YP_004464168.1 COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: clj:CLJU_c41250 rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, , group 3 YP_004464169.1 COGs: COG1351 alternative thymidylate synthase; InterPro IPR003669; KEGG: gme:Gmet_0378 FAD-dependent thymidylate synthase; PFAM: thymidylate synthase complementing protein ThyX; SPTR: Thymidylate synthase complementing protein ThyX; TIGRFAM: thymidylate synthase, flavin-dependent; PFAM: Thymidylate synthase complementing protein; TIGRFAM: thymidylate synthase, flavin-dependent YP_004464170.1 COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: chy:CHY_0730 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_004464171.1 COGs: COG0787 Alanine racemase; InterPro IPR001608: IPR011079: IPR000821: IPR020622; KEGG: pth:PTH_0660 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase YP_004464172.1 COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: cth:Cthe_0616 ACT domain-containing protein; PFAM: amino acid-binding ACT domain protein; SPTR: ACT domain protein; PFAM: ACT domain YP_004464173.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: cth:Cthe_0615 phenylacetate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate-CoA ligase; PFAM: AMP-binding enzyme YP_004464174.1 COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752: IPR017719; KEGG: cth:Cthe_0614 indolepyruvate oxidoreductase subunit beta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit YP_004464175.1 COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR002880: IPR011766: IPR017896: IPR017721; KEGG: cth:Cthe_0613 thiamine pyrophosphate enzyme-like TPP-binding; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Thiamine pyrophosphate enzyme-like TPP-binding; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit YP_004464176.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: cce:Ccel_1756 phenylacetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate--CoA ligase; manually curated; PFAM: AMP-binding enzyme YP_004464177.1 COGs: COG4145 Na+/panthothenate symporter; InterPro IPR001734; KEGG: mvo:Mvol_1550 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: Na+/solute symporter; PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family YP_004464178.1 COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: tmt:Tmath_1611 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system YP_004464179.1 COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: tit:Thit_1621 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system YP_004464180.1 COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: tmt:Tmath_1612 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Glycine betaine/L-proline ABC transporter, permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464181.1 COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR003439: IPR000644: IPR017871: IPR003593: IPR 005892; KEGG: tex:Teth514_1201 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit YP_004464182.1 KEGG: lgs:LEGAS_1100 PhoH-like protein; SPTR: Polymerase PA YP_004464183.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cpo:COPRO5265_1129 transcriptional regulator, PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: Transcriptional regulator, ; PFAM: MarR family YP_004464184.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140: IPR003439: IPR017940: IPR017871: IPR 003593; KEGG: cpo:COPRO5265_1128 ABC-type multidrug/protein/lipid transport system, membrane component; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC-type multidrug/protein/lipid transport system, membrane component; PFAM: ABC transporter transmembrane region; ABC transporter YP_004464185.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140: IPR003439: IPR017940: IPR017871: IPR 003593; KEGG: cpo:COPRO5265_1127 ABC transporter ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004464186.1 COGs: COG1501 Alpha-glucosidase 31 of glycosyl hydrolase; InterPro IPR000322: IPR017871; KEGG: cbe:Cbei_2891 glycoside hydrolase; PFAM: glycoside hydrolase 31; SPTR: Glycoside hydrolase, family 31; PFAM: Glycosyl hydrolases family 31 YP_004464187.1 COGs: COG4555 ABC-type Na+ transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: cth:Cthe_2942 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004464188.1 COGs: COG1668 ABC-type Na+ efflux pump permease component; InterPro IPR013525; KEGG: cac:CA_C3550 Na+ ABC transporter, NatB; PFAM: ABC-2 type transporter; SPTR: Na+ ABC transporter, NATB YP_004464189.1 COGs: COG1160 GTPase; InterPro IPR002917: IPR005225; KEGG: tex:Teth514_0683 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain YP_004464190.1 KEGG: dae:Dtox_2519 hypothetical protein; SPTR: uncharacterized protein YP_004464191.1 COGs: COG3877 conserved hypothetical protein; InterPro IPR018658; KEGG: tte:TTE1661 hypothetical protein; PFAM: Protein of unknown function DUF2089; SPTR: uncharacterized protein; PFAM: Protein of unknown function(DUF2089) YP_004464192.1 KEGG: cbt:CLH_1894 purine nucleoside phosphorylase I, inosine and guanosine-specific; SPTR: Purine nucleoside phosphorylase I, inosine and guanosine-specific YP_004464193.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200: IPR000150: IPR006379; KEGG: sth:STH1403 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: Cof-like hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004464194.1 COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR021127; KEGG: chy:CHY_2151 CRISPR-associated Cas2 family protein; SPTR: CRISPR-associated protein Cas2; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2 YP_004464195.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729: IPR019858; KEGG: pth:PTH_1914 hypothetical protein; PFAM: protein of unknown function DUF48; SPTR: Uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, HMARI/TNEAP subtype; CRISPR-associated endonuclease Cas1 YP_004464196.1 COGs: COG1468 RecB family exonuclease; InterPro IPR013343; KEGG: drm:Dred_0540 CRISPR-associated Cas4 family protein; SPTR: CRISPR-associated protein Cas4; TIGRFAM: CRISPR-associated protein Cas4; PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4 YP_004464197.1 COGs: COG1203 helicase; InterPro IPR014021: IPR001650: IPR006483: IPR006474; KEGG: dth:DICTH_0162 CRISPR-associated helicase Cas3; SPTR: CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD YP_004464198.1 InterPro IPR013421: IPR013422; KEGG: chy:CHY_2155 CRISPR-associated Cas5 family Hmari subtype protein; SPTR: CRISPR-associated protein Cas5, Hmari subtype; TIGRFAM: CRISPR-associated protein Cas5; CRISPR-associated protein Cas5, Hmari subtype; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Hmari subtype; CRISPR-associated protein Cas5, N-terminal domain YP_004464199.1 COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482: IPR013419; KEGG: chy:CHY_2156 CRISPR-associated Csh2 family protein; PFAM: CRISPR-associated protein TM1801; SPTR: CRISPR-associated protein, Csh2 family; TIGRFAM: CRISPR-associated protein, Csh2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csh2 family YP_004464200.1 InterPro IPR013389: IPR013420; KEGG: chy:CHY_2157 CRISPR-associated Csh1 family protein; PFAM: CRISPR-associated protein TM1802; SPTR: CRISPR-associated protein, Csh1 family; TIGRFAM: CRISPR-associated protein, Csh1 family; CRISPR-associated protein, TM1802 family; PFAM: CRISPR-associated protein TM1802 (cas_TM1802); TIGRFAM: CRISPR-associated protein, TM1802 family; CRISPR-associated protein, Csh1 family YP_004464201.1 COGs: COG1583 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR002743: IPR010156; KEGG: tpd:Teth39_0121 CRISPR-associated Cas family protein; PFAM: protein of unknown function DUF57; SPTR: CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein Cas6; PFAM: CRISPR associated protein Cas6; TIGRFAM: CRISPR-associated endoribonuclease Cas6 YP_004464202.1 COGs: COG0433 ATPase; KEGG: bcl:ABC0060 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF87 YP_004464203.1 InterPro IPR018977; KEGG: bcl:ABC0059 hypothetical protein; PFAM: NurA domain; SPTR: NurA domain superfamily; PFAM: NurA domain YP_004464204.1 COGs: COG2002 Regulators of stationary/sporulation gene expression; InterPro IPR007159: IPR006339; KEGG: cbf:CLI_0120 AbrB family transcriptional regulator; PFAM: SpoVT/AbrB domain-containing protein; SPTR: Transcriptional regulator, AbrB family; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family YP_004464205.1 COGs: COG0313 methyltransferase; InterPro IPR000878: IPR008189; KEGG: cbt:CLH_3121 hypothetical protein; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Tetrapyrrole methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family YP_004464206.1 COGs: COG4123 O-methyltransferase; InterPro IPR000241: IPR002052; KEGG: cth:Cthe_2102 methyltransferase small; PFAM: RNA methylase; SPTR: Predicted O-methyltransferase; manually curated; PFAM: Methyltransferase small domain YP_004464207.1 KEGG: csc:Csac_0363 hypothetical protein; SPTR: uncharacterized protein YP_004464208.1 InterPro IPR019196; KEGG: csc:Csac_0364 hypothetical protein; PFAM: ABC-type uncharacterised transport system; SPTR: uncharacterized protein; PFAM: ABC-type uncharacterized transport system YP_004464209.1 KEGG: csc:Csac_0365 hypothetical protein; SPTR: uncharacterized protein YP_004464210.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: csc:Csac_0366 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004464211.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341: IPR013342: IPR018110; KEGG: pjd:Pjdr2_2992 mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain YP_004464212.1 COGs: COG0787 Alanine racemase; InterPro IPR001608: IPR011079: IPR000821: IPR020622; KEGG: swo:Swol_2416 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase YP_004464213.1 COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: dhd:Dhaf_4843 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: Methicillin resistance protein; PFAM: FemAB family YP_004464214.1 InterPro IPR000326; KEGG: tpd:Teth39_0213 phosphoesterase, PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: Phosphoesterase, PA-phosphatase related; PFAM: PAP2 superfamily YP_004464215.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: pjd:Pjdr2_5267 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel YP_004464216.1 InterPro IPR004013: IPR003141; KEGG: cak:Caul_4076 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: PHP domain protein YP_004464217.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_3546 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464218.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_3547 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464219.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_3548 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464220.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000524: IPR001761; KEGG: pjd:Pjdr2_4202 transcriptional regulator, GntR family with LacI sensor; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; family YP_004464221.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: hor:Hore_11260 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, C-terminal alpha/beta domain; Oxidoreductase, NAD-binding Rossmann fold YP_004464222.1 COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; InterPro IPR004039; KEGG: mtp:Mthe_0907 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin-type Fe(Cys)4 protein; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain YP_004464223.1 InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin YP_004464224.1 COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: aoe:Clos_2793 peptidase M1 membrane alanine aminopeptidase; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Peptidase M1 YP_004464225.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140: IPR003439: IPR017940: IPR017871: IPR 003593; KEGG: ate:Athe_0466 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter transmembrane region YP_004464226.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: tjr:TherJR_1002 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464227.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: dae:Dtox_2282 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Taurine ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004464228.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR001638; KEGG: hor:Hore_14770 NlpA lipoprotein; SMART: extracellular solute-binding protein family 3; SPTR: ABC transporter, periplasmic substrate-binding protein; PFAM: NMT1/THI5 like YP_004464229.1 COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR003382: IPR004507; KEGG: slp:Slip_1438 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases YP_004464230.1 COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537: IPR006371; KEGG: gym:GYMC10_0625 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase YP_004464231.1 COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: chy:CHY_1808 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related protein; SPTR: UbiD family decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases YP_004464232.1 COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: bmq:BMQ_4297 phospholipase, PFAM: Patatin; SPTR: Phospholipase, ; PFAM: Patatin-like phospholipase YP_004464233.1 KEGG: bay:RBAM_030530 two-component sensor histidine kinase; SPTR: uncharacterized protein YP_004464234.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR001917; KEGG: csc:Csac_1225 glycine C-acetyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase YP_004464235.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: mpd:MCP_1514 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase YP_004464236.1 COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR002423: IPR001844: IPR018370; KEGG: cth:Cthe_2892 chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: chaperonin GroEL; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004464237.1 COGs: COG0234 Co-chaperonin GroES (HSP10); InterPro IPR020818: IPR001476: IPR018369; KEGG: aoe:Clos_2448 co-chaperonin GroES; PFAM: Chaperonin Cpn10; SPTR: 10 kDa chaperonin; PFAM: Chaperonin 10 Kd subunit YP_004464238.1 COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904: IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg) YP_004464239.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric YP_004464240.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433: IPR019480: IPR017927: IPR012165; KEGG: cth:Cthe_0373 ferredoxin-NADP(+) reductase subunit alpha; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004464241.1 InterPro IPR005531; KEGG: tte:TTE0565 hypothetical protein; PFAM: protein of unknown function DUF322; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF322) YP_004464242.1 COGs: COG1067 ATP-dependent protease; InterPro IPR001984; KEGG: cth:Cthe_1773 peptidase S16, lon-like protein; SPTR: Peptidase S16, lon-like protein; PFAM: Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related ATP-dependent protease YP_004464243.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524: IPR004839; KEGG: amt:Amet_3155 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II YP_004464244.1 COGs: COG0214 Pyridoxine biosynthesis enzyme; InterPro IPR001852; KEGG: tte:TTE0823 pyridoxal biosynthesis lyase PdxS; PFAM: Vitamin B6 biosynthesis protein; SPTR: Pyridoxal biosynthesis lyase pdxS; TIGRFAM: pyridoxine biosynthesis protein; PFAM: SOR/SNZ family; TIGRFAM: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 YP_004464245.1 COGs: COG0311 glutamine amidotransferase involved in pyridoxine biosynthesis; InterPro IPR002161: IPR021196; KEGG: tte:TTE0822 pyridoxine biosynthesis glutamine amidotransferase; PFAM: SNO glutamine amidotransferase; SPTR: SNO glutamine amidotransferase; TIGRFAM: SNO glutamine amidotransferase; PFAM: SNO glutamine amidotransferase; TIGRFAM: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 YP_004464246.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: caa:Caka_0351 uroporphyrinogen-III decarboxylase-like protein; SPTR: Uroporphyrinogen-III decarboxylase-like protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464247.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023: IPR011404; KEGG: mta:Moth_1234 6-phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase; PFAM: Phosphofructokinase YP_004464248.1 InterPro IPR001584; KEGG: tjr:TherJR_2621 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004464249.1 KEGG: tmt:Tmath_0911 SatD; SPTR: SatD YP_004464250.1 KEGG: tit:Thit_0870 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3307) YP_004464251.1 KEGG: bwe:BcerKBAB4_0462 RNA methyltransferase; SPTR: RNA methyltransferase, TrmH family, group 2 YP_004464252.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307: IPR011418; KEGG: tte:TTE1948 sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; AP endonuclease 2 domain protein; SPTR: sugar phosphate isomerase/epimerase; PFAM: AP endonuclease 2 C terminus; Xylose isomerase-like TIM barrel YP_004464253.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: cfl:Cfla_1190 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: myo-inositol 2-dehydrogenase; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004464254.1 COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR013249: IPR001584; KEGG: slp:Slip_1605 integrase catalytic region; PFAM: Sigma-70 region 4 type 2; SPTR: Integrase catalytic region; PFAM: Sigma-70, region 4; Integrase core domain YP_004464255.1 COGs: COG1484 DNA replication protein; InterPro IPR002611: IPR003593; KEGG: slp:Slip_1606 IstB domain protein ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004464256.1 InterPro IPR001387; KEGG: ckr:CKR_2864 hypothetical protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004464257.1 COGs: COG2189 Adenine specific DNA methylase Mod; InterPro IPR002941: IPR002295: IPR002052; KEGG: ckr:CKR_2865 hypothetical protein; PFAM: DNA methylase N-4/N-6 domain protein; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: uncharacterized protein; PFAM: DNA methylase YP_004464258.1 COGs: COG3587 Restriction endonuclease; InterPro IPR006935; KEGG: ckr:CKR_2866 hypothetical protein; PFAM: type III restriction protein res subunit; PRIAM: Type III site-specific deoxyribonuclease; SPTR: uncharacterized protein; PFAM: Type III restriction enzyme, res subunit; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_004464259.1 COGs: COG3593 ATP-dependent endonuclease of the OLD family; InterPro IPR003593; KEGG: ckr:CKR_2867 hypothetical protein; SMART: AAA ATPase; SPTR: uncharacterized protein YP_004464260.1 KEGG: dhd:Dhaf_1738 hypothetical protein; SPTR: uncharacterized protein YP_004464261.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: clj:CLJU_c20380 permease; PFAM: Auxin Efflux Carrier; SPTR: Auxin Efflux Carrier; PFAM: Membrane transport protein; TIGRFAM: he Auxin Efflux Carrier (AEC) Family YP_004464262.1 COGs: COG2843 protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: slp:Slip_0641 capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA; PFAM: Bacterial capsule synthesis protein PGA_cap YP_004464263.1 InterPro IPR018392: IPR002482; KEGG: cth:Cthe_2402 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; PFAM: LysM domain YP_004464264.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766: IPR000399: IPR 012846; KEGG: cth:Cthe_2714 acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type YP_004464265.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR002347: IPR020904; KEGG: slg:SLGD_02533 hypothetical protein; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; PFAM: short chain dehydrogenase YP_004464266.1 COGs: COG1069 Ribulose kinase; InterPro IPR018484: IPR018485: IPR018483: IPR005929; KEGG: tit:Thit_1703 L-ribulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Ribulokinase; TIGRFAM: L-ribulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: L-ribulokinase YP_004464267.1 COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933: IPR016286; KEGG: pjd:Pjdr2_6154 alpha-L-fucosidase; PFAM: glycoside hydrolase 29 (alpha-L-fucosidase); SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase YP_004464268.1 InterPro IPR013738; KEGG: bln:Blon_0346 hypothetical protein; PFAM: Beta-galactosidase trimerisation domain protein; SPTR: uncharacterized protein; PFAM: Beta-galactosidase trimerisation domain; Alpha-L-fucosidase YP_004464269.1 KEGG: ppp:PHYPADRAFT_133065 hypothetical protein; SPTR: uncharacterized protein YP_004464270.1 COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933: IPR016286; KEGG: sus:Acid_4210 alpha-L-fucosidase; PFAM: glycoside hydrolase 29 (alpha-L-fucosidase); SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase YP_004464271.1 InterPro IPR000923; KEGG: tte:TTE2530 ABC-type multidrug transport system, permease component; SPTR: Cysteine--tRNA ligase YP_004464272.1 KEGG: mta:Moth_2111 uroporphyrinogen-III decarboxylase-like; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464273.1 KEGG: cce:Ccel_1018 hypothetical protein; SPTR: uncharacterized protein YP_004464274.1 InterPro IPR003834; KEGG: emi:Emin_0187 hypothetical protein; PFAM: cytochrome c biogenesis protein transmembrane region; SPTR: uncharacterized protein; PFAM: Cytochrome C biogenesis protein transmembrane region YP_004464276.1 KEGG: tan:TA04200 cation-transporting ATPase; SPTR: Cation-transporting ATPase YP_004464277.1 InterPro IPR016518; KEGG: gym:GYMC10_0113 alpha-L-fucosidase; PRIAM: Alpha-L-fucosidase; SPTR: Alpha-L-fucosidase YP_004464278.1 KEGG: mta:Moth_2111 uroporphyrinogen-III decarboxylase-like; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464279.1 KEGG: pti:PHATR_4994 hypothetical protein; SPTR: Predicted protein YP_004464280.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dsy:DSY4756 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464281.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_1005 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464282.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_1004 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component YP_004464283.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_1003 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; manually curated; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464284.1 COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933: IPR016286; KEGG: csc:Csac_1340 alpha-L-fucosidase; PFAM: glycoside hydrolase 29 (alpha-L-fucosidase); PRIAM: Alpha-L-fucosidase; SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase YP_004464285.1 KEGG: cce:Ccel_1018 hypothetical protein; SPTR: uncharacterized protein YP_004464286.1 KEGG: emi:Emin_0187 hypothetical protein; SPTR: Glutaredoxin 2 YP_004464287.1 COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395: IPR020471: IPR018170; KEGG: cce:Ccel_1009 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase YP_004464288.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: cce:Ccel_1007 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004464289.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485; KEGG: cce:Ccel_1006 carbohydrate kinase FGGY; PFAM: Carbohydrate kinase, FGGY-like; PRIAM: Xylulokinase; SPTR: Carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004464290.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: cce:Ccel_1005 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004464291.1 COGs: COG1655 conserved hypothetical protein; InterPro IPR018708: IPR019734; KEGG: tmt:Tmath_0769 protein of unknown function DUF2225; PFAM: Protein of unknown function DUF2225; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2225) YP_004464292.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439: IPR017871: IPR003593; KEGG: cno:NT01CX_0476 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004464293.1 KEGG: drm:Dred_1496 hypothetical protein; SPTR: uncharacterized protein; PFAM: Rubrerythrin YP_004464294.1 COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: tte:TTE2512 hypothetical protein; PFAM: thiamine transporter YuaJ; SPTR: uncharacterized protein; TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: probable proton-coupled thiamine transporter YuaJ YP_004464295.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006175; KEGG: ttr:Tter_1944 endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: Endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP YP_004464296.1 COGs: COG2006 conserved hypothetical protein; InterPro IPR017896: IPR017900; KEGG: dhd:Dhaf_0829 protein of unknown function DUF362; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF362) YP_004464297.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198: IPR002347: IPR020904; KEGG: mxa:MXAN_0774 short chain dehydrogenase/reductase oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short chain dehydrogenase/reductase; PFAM: short chain dehydrogenase YP_004464298.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: cpo:COPRO5265_0449 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Conserved hypothetical membrane protein; PFAM: Sulfite exporter TauE/SafE YP_004464299.1 COGs: COG0393 conserved hypothetical protein; InterPro IPR002765; KEGG: dac:Daci_3728 hypothetical protein; PFAM: protein of unknown function DUF74; SPTR: cytoplasmic protein; PFAM: Domain of unknown function (DUF74) YP_004464300.1 COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125: IPR016192; KEGG: esi:Exig_0017 CMP/dCMP deaminase zinc-binding; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: CMP/dCMP deaminase, zinc-binding; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004464301.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sth:STH1313 sugar ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464302.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sth:STH1312 sugar ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464303.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sth:STH1311 sugar ABC transporter sugar-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464304.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197: IPR018247: IPR001989: IPR012838; KEGG: cdl:CDR20291_0686 pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: uncharacterized protein; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: Radical SAM superfamily; TIGRFAM: pyruvate formate-lyase 1-activating enzyme; glycyl-radical enzyme activating protein family YP_004464305.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR004184: IPR001150: IPR019777: IPR005949; KEGG: cth:Cthe_0505 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1 YP_004464306.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR004099: IPR001763; KEGG: eat:EAT1b_1024 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004464307.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR013096: IPR000005: IPR020449: IPR018060: IPR 018062; KEGG: gym:GYMC10_1369 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Cupin domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464308.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase 4 of glycosyl hydrolase; InterPro IPR001088: IPR019802; KEGG: pjd:Pjdr2_4668 glycoside hydrolase 4; PFAM: glycoside hydrolase 4; SPTR: Glycoside hydrolase 4; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004464309.1 KEGG: cbb:CLD_1627 hypothetical protein; SPTR: membrane protein YP_004464310.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: tjr:TherJR_2703 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004464311.1 COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: mta:Moth_1165 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family YP_004464312.1 KEGG: apv:Apar_1214 ATPase associated with various cellular activities AAA_5; SPTR: ATPase associated with various cellular activities AAA_5 YP_004464313.1 KEGG: gwc:GWCH70_3091 hypothetical protein; SPTR: uncharacterized protein YP_004464314.1 KEGG: abu:Abu_1821 lipid A biosynthesis lauroyl acyltransferase; SPTR: Transposase YP_004464315.1 KEGG: ath:AT4G01180 XH/XS domain-containing protein YP_004464316.1 KEGG: sru:SRU_0755 hypothetical protein; SPTR: uncharacterized protein YP_004464317.1 COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: tit:Thit_2244 HEPN domain protein; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: HEPN domain protein; PFAM: HEPN domain YP_004464318.1 InterPro IPR002934; KEGG: tmt:Tmath_2038 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain YP_004464319.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: ate:Athe_2609 SufBD protein; PFAM: SufBD protein; SPTR: SufBD protein; PFAM: Uncharacterized protein family (UPF0051) YP_004464320.1 COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003439: IPR003593; KEGG: ate:Athe_2608 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_004464321.1 COGs: COG1633 conserved hypothetical protein; InterPro IPR003251; KEGG: ate:Athe_0477 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin; PFAM: Rubrerythrin YP_004464322.1 COGs: COG2407 L-fucose isomerase and related protein; KEGG: ate:Athe_0707 L-fucose isomerase-like protein; SPTR: L-fucose isomerase-like protein; PFAM: L-fucose isomerase, C-terminal domain YP_004464323.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR015590: IPR001670: IPR018211: IPR012079; KEGG: hmo:HM1_2632 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; SPTR: Aldehyde-alcohol dehydrogenase; PFAM: Aldehyde dehydrogenase; Iron-containing alcohol dehydrogenase YP_004464324.1 COGs: COG0465 ATP-dependent Zn protease; InterPro IPR003959: IPR000642: IPR003960: IPR003593: IPR 005936; KEGG: aoe:Clos_1173 ATP-dependent metalloprotease FtsH; PFAM: AAA ATPase central domain protein; peptidase M41; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: FtsH Extracellular; Peptidase M41; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004464325.1 COGs: COG2006 conserved hypothetical protein; KEGG: csc:Csac_1323 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF362) YP_004464326.1 COGs: COG0554 Glycerol kinase; InterPro IPR018484: IPR018485: IPR018483: IPR005999; KEGG: tte:TTE2002 glycerol kinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Glycerol kinase; TIGRFAM: glycerol kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004464327.1 COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835: IPR001538; KEGG: tmt:Tmath_0724 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_004464328.1 KEGG: cth:Cthe_3115 hypothetical protein; SPTR: uncharacterized protein YP_004464329.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: csc:Csac_1729 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1; PFAM: Glycosyl transferases group 1 YP_004464330.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: slp:Slip_1775 glycosidase-related protein; PFAM: glycosidase related protein; SPTR: Glycosidase-related protein; PFAM: Domain of unknown function (DUF377) YP_004464331.1 COGs: COG0728 membrane protein virulence factor; InterPro IPR004268; KEGG: tte:TTE0176 uncharacterized membrane protein, virulence factor; PFAM: virulence factor MVIN family protein; SPTR: Integral membrane protein MviN; TIGRFAM: integral membrane protein MviN; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN YP_004464332.1 COGs: COG0426 flavoprotein; InterPro IPR008254: IPR016440; KEGG: dae:Dtox_2294 beta-lactamase domain protein; PFAM: flavodoxin/nitric oxide synthase; SPTR: Beta-lactamase domain protein; PFAM: Flavodoxin; Metallo-beta-lactamase superfamily YP_004464333.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: clj:CLJU_c01320 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: NAD-dependent protein deacetylases, SIR2 family; PFAM: Sir2 family YP_004464334.1 COGs: COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); InterPro IPR003751; KEGG: bse:Bsel_1031 carbon storage regulator, CsrA; PFAM: carbon storage regulator; SPTR: Carbon storage regulator homolog; TIGRFAM: carbon storage regulator; PFAM: Global regulator protein family; TIGRFAM: carbon storage regulator (csrA) YP_004464335.1 COGs: COG1699 conserved hypothetical protein; InterPro IPR003775; KEGG: cth:Cthe_2240 flagellar assembly protein FliW; PFAM: protein of unknown function DUF180; SPTR: Flagellar assembly factor fliW; PFAM: FliW protein YP_004464336.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492: IPR013384; KEGG: tmt:Tmath_0562 flagellar hook-associated protein 3; PFAM: flagellin domain protein; SPTR: Flagellar hook-associated protein 3; TIGRFAM: flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3 YP_004464337.1 COGs: COG1256 Flagellar hook-associated protein; InterPro IPR001444: IPR010930: IPR002371; KEGG: ate:Athe_1675 flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar hook-associated protein FlgK YP_004464338.1 InterPro IPR007809; KEGG: cth:Cthe_2245 hypothetical protein; PFAM: FlgN family protein; SPTR: uncharacterized protein; PFAM: FlgN protein YP_004464339.1 InterPro IPR007412; KEGG: ate:Athe_1677 anti-sigma-28 factor, FlgM; PFAM: Anti-sigma-28 factor FlgM family protein; SPTR: Anti-sigma-28 factor, FlgM; TIGRFAM: Anti-sigma-28 factor FlgM family protein; PFAM: Anti-sigma-28 factor, FlgM; TIGRFAM: flagellar biosynthesis anti-sigma factor FlgM YP_004464340.1 InterPro IPR022258; KEGG: aoe:Clos_2524 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: Flagellar operon protein YvyF; TIGRFAM: flagellar operon protein TIGR03826 YP_004464341.1 COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: tpd:Teth39_1788 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein YP_004464342.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR003583: IPR003593: IPR006345; KEGG: cth:Cthe_2249 ATP-dependent RecD/TraA family DNA helicase; PRIAM: Exodeoxyribonuclease V; SMART: AAA ATPase; Helix-hairpin-helix DNA-binding class 1; SPTR: ATP-dependent DNA helicase, RecD/TraA family; TIGRFAM: helicase, RecD/TraA family; PFAM: ATPase (DUF699); TIGRFAM: helicase, , RecD/TraA family YP_004464343.1 KEGG: aoe:Clos_2608 hypothetical protein; SPTR: uncharacterized protein; PFAM: ComK protein YP_004464344.1 COGs: COG1274 Phosphoenolpyruvate carboxykinase (GTP); InterPro IPR008209: IPR018091; KEGG: ate:Athe_0393 phosphoenolpyruvate carboxykinase; PFAM: phosphoenolpyruvate carboxykinase (GTP); PRIAM: Phosphoenolpyruvate carboxykinase (GTP); SPTR: Phosphoenolpyruvate carboxykinase (GTP); PFAM: Phosphoenolpyruvate carboxykinase YP_004464345.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR004176: IPR003959: IPR001943: IPR013093: IPR 019489: IPR001270: IPR018368: IPR003593; KEGG: tjr:TherJR_0243 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); UvrB/uvrC motif YP_004464346.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tye:THEYE_A0363 heat shock protein, HSP20 family; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein, Hsp20 family; PFAM: Hsp20/alpha crystallin family YP_004464347.1 COGs: COG1773 Rubredoxin; InterPro IPR004039: IPR001052: IPR018527; KEGG: mta:Moth_0620 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; PFAM: Rubredoxin YP_004464348.1 InterPro IPR012851; KEGG: mta:Moth_1782 coat F domain-containing protein; PFAM: Coat F domain protein; SPTR: Coat F; PFAM: Coat F domain YP_004464349.1 KEGG: mta:Moth_1783 hypothetical protein; SPTR: uncharacterized protein; PFAM: Coat F domain YP_004464350.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611: IPR002139: IPR002173: IPR011877; KEGG: ppr:PBPRB1560 ribokinase; PFAM: PfkB domain protein; SPTR: ribokinase; TIGRFAM: ribokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase YP_004464351.1 COGs: COG0572 Uridine kinase; KEGG: tte:TTE1778 uridine kinase; SPTR: Phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase YP_004464352.1 COGs: COG4213 ABC-type xylose transport system periplasmic component; InterPro IPR001761: IPR013456; KEGG: tmt:Tmath_0329 D-xylose ABC transporter, periplasmic substrate-binding protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: D-xylose ABC transporter, periplasmic substrate-binding protein; TIGRFAM: D-xylose ABC transporter, periplasmic substrate-binding protein; PFAM: family; TIGRFAM: D-xylose ABC transporter, substrate-binding protein YP_004464353.1 COGs: COG4214 ABC-type xylose transport system permease component; InterPro IPR001851; KEGG: tmt:Tmath_0331 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004464354.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439: IPR013455: IPR017871: IPR003593; KEGG: tmt:Tmath_0330 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004464355.1 COGs: COG4213 ABC-type xylose transport system periplasmic component; InterPro IPR001761; KEGG: tmt:Tmath_0329 D-xylose ABC transporter, periplasmic substrate-binding protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: D-xylose ABC transporter, periplasmic substrate-binding protein; PFAM: family; TIGRFAM: D-xylose ABC transporter, substrate-binding protein YP_004464356.1 COGs: COG4213 ABC-type xylose transport system periplasmic component; KEGG: tmt:Tmath_0328 monosaccharide-transporting ATPase; SPTR: Periplasmic binding protein/LacI family transcriptional regulator; PFAM: family; TIGRFAM: D-xylose ABC transporter, substrate-binding protein YP_004464357.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR000005: IPR020449: IPR018060: IPR 018062; KEGG: tex:Teth514_0224 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Response regulator receiver protein; manually curated; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464358.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR010559: IPR003594: IPR005467; KEGG: tit:Thit_0243 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464359.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: tte:TTE0286 periplasmic sugar-binding proteins; SPTR: Periplasmic sugar-binding proteins; PFAM: family YP_004464360.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR003660: IPR000160; KEGG: drm:Dred_0651 diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: HAMP domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004464361.1 InterPro IPR007530; KEGG: dhd:Dhaf_2449 adenylyltransferase; PFAM: adenylyltransferase; SPTR: uncharacterized protein; PFAM: Streptomycin adenylyltransferase YP_004464362.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_4383 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport system inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464363.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_5024 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464364.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_4382 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464365.1 COGs: COG2045 Phosphosulfolactate phosphohydrolase; InterPro IPR005238; KEGG: tpd:Teth39_0568 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase; SPTR: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase YP_004464366.1 COGs: COG0700 membrane protein; InterPro IPR011642; KEGG: afw:Anae109_0346 nucleoside recognition domain-containing protein; PFAM: nucleoside recognition domain protein; SPTR: Nucleoside recognition domain protein; PFAM: Nucleoside recognition YP_004464367.1 COGs: COG2715 Uncharacterized membrane protein required for spore maturation in B.subtilis.; InterPro IPR011642; KEGG: cth:Cthe_2099 nucleoside recognition; PFAM: nucleoside recognition domain protein; SPTR: Nucleoside recognition YP_004464368.1 KEGG: tmt:Tmath_1587 hypothetical protein; SPTR: uncharacterized protein; PFAM: Spore coat associated protein JA (CotJA) YP_004464369.1 InterPro IPR016571; KEGG: tex:Teth514_1214 hypothetical protein; SPTR: uncharacterized protein YP_004464370.1 COGs: COG3546 Mn-containing catalase; InterPro IPR007760; KEGG: cth:Cthe_0414 manganese containing catalase; PFAM: manganese containing catalase; SPTR: Manganese containing catalase; PFAM: Manganese containing catalase YP_004464371.1 KEGG: bcu:BCAH820_4412 hypothetical protein; SPTR: uncharacterized protein YP_004464372.1 InterPro IPR006199; KEGG: cwo:Cwoe_4471 transcriptional repressor, LexA family; PFAM: LexA DNA-binding domain protein; SPTR: LexA repressor; PFAM: LexA DNA binding domain YP_004464373.1 InterPro IPR002711: IPR003615; KEGG: taf:THA_1264 HNH endonuclease domain protein; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease domain protein; PFAM: HNH endonuclease YP_004464374.1 COGs: COG2206 HD-GYP domain; InterPro IPR006674; KEGG: tjr:TherJR_0515 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain YP_004464375.1 KEGG: tte:TTE2045 hypothetical protein; SPTR: uncharacterized protein YP_004464376.1 KEGG: tte:TTE2048 hypothetical protein; SPTR: uncharacterized protein YP_004464377.1 KEGG: tpd:Teth39_0079 hypothetical protein; SPTR: uncharacterized protein YP_004464378.1 KEGG: tpd:Teth39_0044 StbA family protein; SPTR: StbA family protein; PFAM: StbA protein YP_004464379.1 InterPro IPR000045; KEGG: tte:TTE2059 hypothetical protein; PFAM: peptidase A24A prepilin type IV; SPTR: uncharacterized protein; PFAM: Type IV leader peptidase YP_004464380.1 KEGG: tte:TTE2060 hypothetical protein; SPTR: uncharacterized protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004464381.1 KEGG: tte:TTE2063 hypothetical protein; SPTR: uncharacterized protein YP_004464382.1 KEGG: tte:TTE2065 hypothetical protein; SPTR: uncharacterized protein YP_004464383.1 InterPro IPR018076; KEGG: tte:TTE2066 hypothetical protein; PFAM: Type II secretion system F domain; SPTR: uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain YP_004464384.1 InterPro IPR018076; KEGG: tte:TTE2067 hypothetical protein; PFAM: Type II secretion system F domain; SPTR: uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain YP_004464385.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482: IPR002078: IPR003593; KEGG: tte:TTE2075 ATPase; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Predicted ATPases involved in pili and flagella biosynthesis, VirB11 family; PFAM: Type II/IV secretion system protein YP_004464386.1 KEGG: tte:TTE2076 septum formation inhibitor-activating ATPase; SPTR: Septum formation inhibitor-activating ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004464387.1 KEGG: tte:TTE2077 hypothetical protein; SPTR: uncharacterized protein YP_004464388.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR003343: IPR016047: IPR001412; KEGG: pjd:Pjdr2_3565 S-layer domain protein; PFAM: Peptidase M23; Ig domain protein group 2 domain protein; SMART: Ig domain protein group 2 domain protein; SPTR: S-layer domain protein; PFAM: Bacterial Ig-like domain (group 2); cell wall binding repeat 2; Peptidase M23 YP_004464389.1 KEGG: tpd:Teth39_2221 hypothetical protein; SPTR: uncharacterized protein YP_004464390.1 KEGG: cbi:CLJ_0225 hypothetical protein; SPTR: uncharacterized protein YP_004464391.1 KEGG: tte:TTE2065 hypothetical protein; SPTR: uncharacterized protein; PFAM: TadE-like protein YP_004464392.1 InterPro IPR018076; KEGG: csc:Csac_1430 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain YP_004464393.1 InterPro IPR018076; KEGG: csc:Csac_1429 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain YP_004464394.1 KEGG: tte:TTE2076 septum formation inhibitor-activating ATPase; SPTR: Septum formation inhibitor-activating ATPase YP_004464395.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482: IPR002078; KEGG: ate:Athe_2453 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein YP_004464396.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: csc:Csac_1427 chromosome partitioning ATPase; SPTR: ATPase involved in chromosome partitioning-like protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004464397.1 InterPro IPR013974; KEGG: csc:Csac_1426 hypothetical protein; PFAM: SAF domain protein; SPTR: uncharacterized protein; PFAM: SAF domain YP_004464398.1 KEGG: tte:TTE2088 hypothetical protein; SPTR: uncharacterized protein YP_004464399.1 KEGG: tga:TGAM_2006 regulatory protein HTH/ArsR family, disease resistance-related, containing ATPase domain; SPTR: Regulatory protein HTH/ArsR family, disease resistance-related, containing ATPase domain YP_004464400.1 KEGG: ele:Elen_2113 hypothetical protein; SPTR: uncharacterized protein YP_004464401.1 KEGG: tgu:100231682 similar to mCG21813; SPTR: uncharacterized protein YP_004464402.1 KEGG: tde:TDE2735 surface antigen, SPTR: Surface antigen BspA YP_004464403.1 InterPro IPR007404: IPR016956; KEGG: drm:Dred_0842 membrane-bound metal-dependent hydrolase; PFAM: membrane-bound metal-dependent hydrolase; SPTR: Membrane-bound metal-dependent hydrolase; PFAM: Predicted membrane-bound metal-dependent hydrolase (DUF457) YP_004464404.1 InterPro IPR002711: IPR003615; KEGG: ate:Athe_2426 HNH endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; PFAM: HNH endonuclease YP_004464405.1 KEGG: pjd:Pjdr2_4004 glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Starch synthase catalytic domain YP_004464406.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR008258: IPR016047; KEGG: drm:Dred_0935 peptidase M23B; PFAM: Peptidase M23; Lytic transglycosylase catalytic; SPTR: Peptidase M23B; PFAM: Transglycosylase SLT domain; Peptidase M23 YP_004464407.1 KEGG: pfh:PFHG_01233 conserved hypothetical protein; SPTR: uncharacterized protein YP_004464408.1 KEGG: cgr:CAGL0K13024g hypothetical protein; SPTR: Similarities with uniprot|P08640 Saccharomyces cerevisiae YIR019c STA1; PFAM: Glycine rich protein family YP_004464409.1 KEGG: dal:Dalk_5199 hypothetical protein; SPTR: uncharacterized protein YP_004464410.1 KEGG: fpl:Ferp_2190 HEPN domain protein; SPTR: HEPN domain protein YP_004464411.1 InterPro IPR002934; KEGG: ate:Athe_1643 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: uncharacterized protein; PFAM: Nucleotidyltransferase domain YP_004464412.1 KEGG: rfe:RF_1281 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein ( transposase or invertase) YP_004464413.1 COGs: COG4374 conserved hypothetical protein; InterPro IPR002716; KEGG: ava:Ava_1729 PilT protein-like; PFAM: PilT protein domain protein; SPTR: PilT protein-like protein; PFAM: PIN domain YP_004464414.1 KEGG: dae:Dtox_2459 hypothetical protein; SPTR: RecF/RecN/SMC N domain YP_004464415.1 KEGG: sgl:SG1089 hypothetical protein; SPTR: Hypothetical phage protein YP_004464416.1 COGs: COG5279 Uncharacterized protein involved in cytokinesis contains TGc (transglutaminase/protease-like) domain; InterPro IPR007253: IPR002931; KEGG: dhd:Dhaf_4476 Ig domain protein group 2 domain protein; PFAM: transglutaminase domain-containing protein; cell wall binding repeat 2-containing protein; SPTR: LytC; PFAM: Transglutaminase-like superfamily; cell wall binding repeat 2 YP_004464417.1 KEGG: hut:Huta_1506 hypothetical protein; SPTR: uncharacterized protein YP_004464418.1 KEGG: adg:Adeg_0733 hypothetical protein; SPTR: uncharacterized protein YP_004464419.1 KEGG: sto:ST2396 quinol oxidase polypeptide I; SPTR: 524aa long hypothetical quinol oxidase polypeptide I YP_004464420.1 KEGG: cnb:CNBJ0240 hypothetical protein; SPTR: MFS transporter YP_004464421.1 COGs: COG3451 Type IV secretory pathway VirB4 protein; KEGG: cbi:CLJ_0238 AAA ATPase; SPTR: AAA ATPase; PFAM: Domain of unknown function DUF87 YP_004464422.1 KEGG: cbi:CLJ_0239 hypothetical protein; SPTR: uncharacterized protein; PFAM: F pilus assembly Type-IV secretion system for plasmid transfer YP_004464423.1 KEGG: cbi:CLJ_0240 hypothetical protein; SPTR: uncharacterized protein YP_004464424.1 KEGG: tte:TTE2101 hypothetical protein; SPTR: uncharacterized protein YP_004464425.1 KEGG: abc:ACICU_p0069 hypothetical protein; SPTR: uncharacterized protein YP_004464426.1 KEGG: cbi:CLJ_0245 hypothetical protein; SPTR: uncharacterized protein YP_004464427.1 KEGG: tmt:Tmath_0055 hypothetical protein; SPTR: uncharacterized protein YP_004464428.1 KEGG: ddf:DEFDS_1679 ABC transporter ATP-binding protein; SPTR: ABC transporter, ATP-binding protein YP_004464429.1 KEGG: tte:TTE2017 hypothetical protein; SPTR: uncharacterized protein YP_004464430.1 KEGG: tte:TTE2018 DNA primase; SPTR: DNA primase (Bacterial type) YP_004464431.1 KEGG: tte:TTE2019 hypothetical protein; SPTR: uncharacterized protein YP_004464432.1 COGs: COG2003 DNA repair protein; InterPro IPR001405: IPR020891; KEGG: aac:Aaci_3004 DNA repair protein RadC; PFAM: DNA repair protein RadC; SPTR: DNA repair protein RadC; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc YP_004464433.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: cac:CA_C0002 DNA polymerase III subunit beta; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: DNA polymerase III beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit YP_004464435.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424: IPR011344; KEGG: cac:CA_C3723 single strand DNA binding protein, ssb; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein 3; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004464436.1 KEGG: sgl:SG1089 hypothetical protein; SPTR: Hypothetical phage protein YP_004464437.1 InterPro IPR001387; KEGG: cth:Cthe_2460 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix YP_004464438.1 InterPro IPR001387; KEGG: drm:Dred_0875 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix YP_004464439.1 KEGG: amt:Amet_0842 phage protein; SPTR: Phage protein YP_004464440.1 COGs: COG1484 DNA replication protein; InterPro IPR002611: IPR003593; KEGG: amt:Amet_2601 IstB ATP binding domain-containing protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: IstB-like ATP binding protein YP_004464441.1 KEGG: cce:Ccel_1844 hypothetical protein; SPTR: uncharacterized protein YP_004464442.1 COGs: COG4422 Bacteriophage protein gp37; InterPro IPR011101; KEGG: hmo:HM1_0038 phage GP37/gp68, PFAM: Gp37Gp68 family protein; SPTR: Gp37Gp68 family protein; PFAM: Phage protein Gp37/Gp68 YP_004464443.1 KEGG: tet:TTHERM_00310490 cyclic nucleotide-binding domain containing protein; SPTR: uncharacterized protein YP_004464444.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: mem:Memar_1113 DNA polymerase beta subunit; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase, beta domain protein region; PFAM: Nucleotidyltransferase domain YP_004464445.1 SPTR: peptidase YP_004464446.1 KEGG: swd:Swoo_0652 galactokinase YP_004464447.1 KEGG: tca:656579 myosin 9; SPTR: uncharacterized protein YP_004464448.1 KEGG: mcl:MCCL_1400 hypothetical protein; SPTR: uncharacterized protein YP_004464449.1 COGs: COG5279 Uncharacterized protein involved in cytokinesis contains TGc (transglutaminase/protease-like) domain; InterPro IPR002931: IPR007253; KEGG: dhd:Dhaf_4489 glycoside hydrolase 18; PFAM: transglutaminase domain-containing protein; cell wall binding repeat 2-containing protein; SMART: transglutaminase domain-containing protein; SPTR: Cell wall hydrolase/autolysin; PFAM: Transglutaminase-like superfamily; cell wall binding repeat 2 YP_004464450.1 KEGG: cts:Ctha_2318 fructosamine kinase; SPTR: Alpha-rhamnosidase YP_004464451.1 KEGG: dba:Dbac_2006 putrescine--2-oxoglutarate aminotransferase; SPTR: Ribosomal protein YP_004464452.1 KEGG: hde:HDEF_1399 partitioning protein; SPTR: uncharacterized protein YP_004464453.1 KEGG: ere:EUBREC_1157 hypothetical protein; SPTR: uncharacterized protein YP_004464454.1 KEGG: adg:Adeg_1445 sec-C motif domain protein; SPTR: uncharacterized protein YP_004464455.1 COGs: COG0328 Ribonuclease HI; InterPro IPR002156; KEGG: cyc:PCC7424_4219 ribonuclease H; PFAM: ribonuclease H; SPTR: Ribonuclease H; PFAM: RNase H YP_004464456.1 KEGG: csa:Csal_0024 aminopeptidase P; SPTR: Aminopeptidase P. Metallo peptidase. MEROPS family M24B YP_004464457.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: cpo:COPRO5265_0041 tyrosine recombinase XerD; PFAM: integrase; integrase domain protein SAM domain protein; SPTR: Tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase YP_004464458.1 KEGG: tbd:Tbd_2653 hypothetical protein; SPTR: Oxidoreductase domain protein YP_004464459.1 KEGG: aac:Aaci_3003 hypothetical protein; SPTR: uncharacterized protein YP_004464460.1 KEGG: gau:GAU_3896 hypothetical protein; SPTR: uncharacterized protein YP_004464461.1 KEGG: reh:H16_B1630 acetate kinase; SPTR: uncharacterized protein YP_004464462.1 KEGG: ptm:GSPATT00039374001 hypothetical protein; SPTR: Long-chain-fatty-acid--CoA ligase YP_004464463.1 KEGG: cth:Cthe_2464 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacteriophage Mu Gam like protein YP_004464464.1 KEGG: spu:584270 similar to LOC495034 protein; SPTR: uncharacterized protein YP_004464465.1 KEGG: tte:TTE2033 hypothetical protein; SPTR: uncharacterized protein YP_004464466.1 KEGG: ppl:POSPLDRAFT_127891 hypothetical protein YP_004464467.1 KEGG: pru:PRU_2774 toprim domain-containing protein; SPTR: Toprim domain protein YP_004464468.1 KEGG: hla:Hlac_3006 hypothetical protein; SPTR: uncharacterized protein YP_004464469.1 InterPro IPR019825; KEGG: lsp:Bsph_p010 hypothetical protein; SPTR: uncharacterized protein YP_004464470.1 KEGG: tkm:TK90_0324 protein of unknown function DUF335 SprT YP_004464471.1 KEGG: tra:Trad_2770 response regulator receiver protein; SPTR: uncharacterized protein YP_004464472.1 KEGG: aav:Aave_4732 multi-sensor hybrid histidine kinase; SPTR: uncharacterized protein YP_004464473.1 COGs: COG3864 conserved hypothetical protein; InterPro IPR002035; KEGG: dhd:Dhaf_1912 hypothetical protein; PFAM: von Willebrand factor type A; SPTR: uncharacterized protein; PFAM: Predicted metallopeptidase (DUF2201) YP_004464474.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR003593: IPR011703; KEGG: dsy:DSY3507 hypothetical protein; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ATPase associated with various cellular activities (AAA) YP_004464475.1 KEGG: mbr:MONBRDRAFT_26507 hypothetical protein; SPTR: Predicted protein YP_004464477.1 COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: slp:Slip_1606 IstB domain protein ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004464478.1 COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR013249: IPR001584; KEGG: slp:Slip_1605 integrase catalytic region; PFAM: Sigma-70 region 4 type 2; SPTR: Integrase catalytic region; PFAM: Sigma-70, region 4; Integrase core domain YP_004464480.1 KEGG: cyn:Cyan7425_3358 hypothetical protein; SPTR: uncharacterized protein YP_004464481.1 COGs: COG4586 ABC-type uncharacterized transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: cce:Ccel_2522 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004464482.1 KEGG: mbu:Mbur_0866 transposase; SPTR: uncharacterized protein; PFAM: Transposase IS66 family YP_004464483.1 COGs: COG3694 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: dth:DICTH_1813 hypothetical protein; PFAM: protein of unknown function DUF990; SPTR: Membrane protein, ; PFAM: Protein of unknown function (DUF990) YP_004464484.1 COGs: COG4587 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: rlt:Rleg2_2221 protein of unknown function DUF990; PFAM: protein of unknown function DUF990; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF990) YP_004464485.1 KEGG: clj:CLJU_c32630 IS4-like transposase; SPTR: uncharacterized protein YP_004464486.1 KEGG: tet:TTHERM_01205340 IP3 receptor calcium ion channel protein; SPTR: Periplasmic Sensor Signal Transduction Histidine Kinase YP_004464487.1 KEGG: sfu:Sfum_2373 HPr kinase; SPTR: HPr kinase YP_004464488.1 COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR005946; KEGG: eel:EUBELI_01922 phosphoribosylpyrophosphate synthetase; PFAM: phosphoribosyltransferase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004464489.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197: IPR003016; KEGG: pmo:Pmob_1570 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004464490.1 COGs: COG1484 DNA replication protein; InterPro IPR001270: IPR003593: IPR002611; KEGG: chy:CHY_1116 ISChy4, transposition helper protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: ISChy4, transposition helper protein; PFAM: IstB-like ATP binding protein YP_004464491.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638: IPR007197; KEGG: tex:Teth514_0349 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004464492.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: geo:Geob_3352 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004464493.1 KEGG: syg:sync_0302 CinA-like protein YP_004464494.1 InterPro IPR003615: IPR002711; KEGG: ate:Athe_2426 HNH endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; PFAM: HNH endonuclease YP_004464495.1 KEGG: ctp:CTRG_02757 hypothetical protein; SPTR: Predicted protein YP_004464496.1 KEGG: tra:Trad_2770 response regulator receiver protein; SPTR: Response regulator receiver protein YP_004464497.1 KEGG: aav:Aave_4732 multi-sensor hybrid histidine kinase; SPTR: uncharacterized protein YP_004464498.1 COGs: COG3864 conserved hypothetical protein; InterPro IPR002035; KEGG: dhd:Dhaf_1912 hypothetical protein; PFAM: von Willebrand factor type A; SPTR: uncharacterized protein; PFAM: Predicted metallopeptidase (DUF2201) YP_004464499.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR003593: IPR011703; KEGG: dsy:DSY3507 hypothetical protein; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: AAA domain (dynein-related subfamily) YP_004464500.1 KEGG: mbr:MONBRDRAFT_26507 hypothetical protein; SPTR: Predicted protein YP_004464501.1 InterPro IPR003091: IPR013099; KEGG: efa:EF2854 ion transporter, PFAM: Ion transport 2 domain protein; SPTR: uncharacterized protein; PFAM: Ion channel YP_004464502.1 KEGG: hje:HacjB3_19223 hypothetical protein; SPTR: Protocadherin-24 YP_004464503.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); KEGG: cth:Cthe_2752 beta-lactamase-like protein; SPTR: Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily YP_004464504.1 KEGG: cbe:Cbei_1950 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2325) YP_004464505.1 KEGG: dya:Dyak_GE15480 GE15480 gene product from transcript GE15480-RA; SPTR: GE15480 YP_004464506.1 COGs: COG5421 Transposase; InterPro IPR002559; KEGG: swo:Swol_2238 transposase; PFAM: transposase IS4 family protein; SPTR: uncharacterized protein; PFAM: Transposase DDE domain YP_004464507.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR003593; KEGG: cth:Cthe_2249 ATP-dependent RecD/TraA family DNA helicase; SMART: AAA ATPase; SPTR: Helicase, RecD/TraA family; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, , RecD/TraA family YP_004464508.1 KEGG: cbo:CBO2313 lipoprotein; SPTR: lipoprotein YP_004464509.1 KEGG: ste:STER_0972 CRISPR-associated RAMP superfamily protein; SPTR: CRISPR-associated protein Cas6; PFAM: Uncharacterized conserved protein (DUF2276) YP_004464510.1 KEGG: sfv:SFV_1072 IS629 ORF2; SPTR: IS629 ORF2; TIGRFAM: CRISPR-associated protein, Csf3 family YP_004464511.1 KEGG: mgi:Mflv_5433 hypothetical protein; SPTR: uncharacterized protein YP_004464512.1 KEGG: afr:AFE_1038 CRISPR-associated protein, Csf1 family; SPTR: CRISPR-associated protein, Csf1 family YP_004464513.1 KEGG: sna:Snas_5590 hypothetical protein; SPTR: uncharacterized protein YP_004464514.1 COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR014001: IPR007409: IPR006935: IPR014021: IPR 004473; KEGG: tai:Taci_1543 type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; PRIAM: Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase; SPTR: Type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; Type I restriction and modification enzyme - subunit R C terminal; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family YP_004464515.1 COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: bll:BLJ_0171 type I restriction-modification system specificity determinant; PFAM: restriction modification system DNA specificity domain; SPTR: Restriction endonuclease S subunit; PFAM: Type I restriction modification DNA specificity domain YP_004464516.1 InterPro IPR000055; KEGG: seu:SEQ_1976 type I restriction-modification system S protein; PFAM: restriction modification system DNA specificity domain; SPTR: Type I restriction-modification system S protein; PFAM: Type I restriction modification DNA specificity domain YP_004464517.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002296: IPR003356: IPR002052: IPR004546; KEGG: tai:Taci_1545 type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; SPTR: Type I restriction-modification system, M subunit; TIGRFAM: type I restriction-modification system, M subunit; manually curated; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004464518.1 COGs: COG0338 Site-specific DNA methylase; InterPro IPR002294: IPR012327: IPR002052; KEGG: drm:Dred_0878 D12 class N6 adenine-specific DNA methyltransferase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: D12 class N6 adenine-specific DNA methyltransferase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_004464519.1 KEGG: drm:Dred_0879 hypothetical protein; SPTR: uncharacterized protein YP_004464520.1 InterPro IPR002514; KEGG: swo:Swol_2510 transposase IS3/IS911; PFAM: transposase IS3/IS911 family protein; SPTR: Transposase IS3/IS911; PFAM: Transposase YP_004464521.1 KEGG: pmx:PERMA_1539 DNA polymerase III, beta subunit; SPTR: Phage infection protein YP_004464522.1 KEGG: sad:SAAV_2214 FmtB protiein; SPTR: FmtB protein YP_004464524.1 InterPro IPR002559; KEGG: ckr:CKR_0346 hypothetical protein; PFAM: transposase IS4 family protein; SPTR: uncharacterized protein YP_004464525.1 KEGG: bbe:BBR47_53900 hypothetical protein; SPTR: Phage replication protein YP_004464526.1 KEGG: cac:CA_C1971 hypothetical protein; SPTR: uncharacterized protein YP_004464527.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: tte:TTE2040 ribosomal protein S1; SPTR: Ribosomal protein S1; PFAM: S1 RNA binding domain YP_004464528.1 COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR003688; KEGG: tte:TTE2042 conjugal plasmid transfer ATPase; PFAM: TRAG family protein; SPTR: ATPase involved in conjugal plasmid transfer; PFAM: TraG/TraD family YP_004464529.1 KEGG: tte:TTE2125 transcriptional regulator; SPTR: Immunity repressor protein (Phage-related protein); PFAM: Helix-turn-helix YP_004464530.1 COGs: COG2856 Zn peptidase; InterPro IPR010359: IPR020537; KEGG: cth:Cthe_2459 hypothetical protein; PFAM: protein of unknown function DUF955; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF955) YP_004464531.1 InterPro IPR006119: IPR011109; KEGG: bcu:BCAH820_4417 recombinase; PFAM: Recombinase; Resolvase domain; SPTR: Resolvase; PFAM: Recombinase; Resolvase, N terminal domain YP_004464532.1 InterPro IPR001387; KEGG: tte:TTE2125 transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Predicted Transcriptional regulator; PFAM: Helix-turn-helix YP_004464533.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ttr:Tter_2041 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464534.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tmt:Tmath_1701 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464535.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ttr:Tter_2040 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464536.1 InterPro IPR019563; KEGG: htu:Htur_3876 glycoside hydrolase 97; PFAM: Glycoside hydrolase 97; SPTR: Alpha-glucosidase; PFAM: Glycoside hydrolase 97 YP_004464537.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: pjd:Pjdr2_1800 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_004464538.1 InterPro IPR006076: IPR001327; KEGG: hor:Hore_13170 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase YP_004464539.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_1656 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein YP_004464540.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_1804 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464541.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2438 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464542.1 KEGG: cpo:COPRO5265_1483 hypothetical integral membrane protein; SPTR: Hypothetical integral membrane protein YP_004464543.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: aoe:Clos_2530 ECF subfamily RNA polymerase sigma-24 factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004464544.1 InterPro IPR012454; KEGG: mta:Moth_1793 hypothetical protein; PFAM: protein of unknown function DUF1659; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1659) YP_004464545.1 KEGG: mta:Moth_1792 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2922) YP_004464546.1 KEGG: nth:Nther_2545 hypothetical protein; SPTR: uncharacterized protein YP_004464547.1 InterPro IPR008764; KEGG: tex:Teth514_0596 peptidase U57, YabG; PFAM: peptidase U57 YabG; SPTR: Peptidase U57, YabG; TIGRFAM: sporulation peptidase YabG; PFAM: YabG peptidase U57; TIGRFAM: sporulation peptidase YabG YP_004464548.1 COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; InterPro IPR000534: IPR012280: IPR000706; KEGG: cth:Cthe_1863 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form YP_004464549.1 COGs: COG0548 Acetylglutamate kinase; InterPro IPR001057: IPR001048: IPR011148: IPR004662; KEGG: cce:Ccel_2911 acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Acetylglutamate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: acetylglutamate kinase; PFAM: Amino acid kinase; TIGRFAM: acetylglutamate kinase YP_004464550.1 COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835: IPR005771; KEGG: amt:Amet_0295 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; SPTR: UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase YP_004464551.1 COGs: COG3935 primosome component and related protein; InterPro IPR017019: IPR006343; KEGG: tpd:Teth39_0100 primosome, DnaD subunit; SPTR: DNA replication protein DnaD; TIGRFAM: primosome, DnaD subunit; PFAM: Replication initiation and membrane attachment protein (DnaB); TIGRFAM: DnaD and phage-associated domain YP_004464552.1 COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: tpd:Teth39_0099 DNA replication protein DnaC; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: IstB-like ATP binding protein YP_004464553.1 KEGG: tmt:Tmath_0339 hypothetical protein; SPTR: uncharacterized protein; PFAM: transposase, YhgA-like YP_004464554.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cbe:Cbei_2413 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004464555.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ttr:Tter_2001 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464556.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ttr:Tter_2000 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464557.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059: IPR022272; KEGG: ttr:Tter_1999 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein YP_004464558.1 COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: tna:CTN_1622 transketolase, N-terminal subunit; PFAM: Transketolase domain-containing protein; SPTR: Transketolase, N-terminal subunit; PFAM: Transketolase, thiamine diphosphate binding domain YP_004464559.1 COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475: IPR005476; KEGG: bvu:BVU_0358 transketolase, C-terminal subunit; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase, C-terminal subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_004464560.1 InterPro IPR002355: IPR013516; KEGG: sus:Acid_6525 hypothetical protein; SPTR: uncharacterized protein YP_004464561.1 COGs: COG0554 Glycerol kinase; InterPro IPR018484: IPR018485: IPR018483: IPR005999; KEGG: bvu:BVU_0357 glycerol kinase 2; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Glycerol kinase; TIGRFAM: glycerol kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004464562.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: ere:EUBREC_2561 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004464563.1 COGs: COG2407 L-fucose isomerase and related protein; KEGG: lmc:Lm4b_01051 hypothetical protein; SPTR: uncharacterized protein YP_004464564.1 KEGG: bth:BT_0340 trimethylamine corrinoid protein 2 (TCP 2); SPTR: B12 binding domain./Pterin binding enzyme YP_004464565.1 COGs: COG1501 Alpha-glucosidase 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: cce:Ccel_1004 glycoside hydrolase 31; PFAM: glycoside hydrolase 31; SPTR: Glycoside hydrolase 31; PFAM: Glycosyl hydrolases family 31 YP_004464566.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cbe:Cbei_0771 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464567.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: cbe:Cbei_0770 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464568.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cbe:Cbei_0769 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding protein YP_004464569.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR020449: IPR001789: IPR018060: IPR000005: IPR 018062; KEGG: cbe:Cbei_0767 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464570.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR010559: IPR003594: IPR001412; KEGG: cbe:Cbei_0768 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464571.1 InterPro IPR004360; KEGG: cce:Ccel_3377 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004464572.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006101: IPR006104: IPR006102: IPR006103; KEGG: bde:BDP_2211 LacZ6 beta-galactosidase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 2 TIM barrel; SPTR: Sugar binding domain protein, glycosyl hydrolase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain YP_004464573.1 COGs: COG3664 Beta-xylosidase; InterPro IPR000514; KEGG: csc:Csac_2404 glycoside hydrolase; PFAM: glycoside hydrolase 39; SPTR: Glycoside hydrolase 39; PFAM: Glycosyl hydrolases family 39 YP_004464574.1 InterPro IPR013737: IPR008902: IPR016007; KEGG: dth:DICTH_0289 alpha-rhamnosidase; PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; SPTR: Alpha-rhamnosidase; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain YP_004464575.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csc:Csac_1104 response regulator receiver protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Response regulator receiver protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464576.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_5099 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464577.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_5098 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464578.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR018060: IPR000005: IPR018062; KEGG: csc:Csac_1104 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464579.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR010559: IPR003594; KEGG: csc:Csac_1103 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Histidine kinase internal region; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464580.1 KEGG: nth:Nther_2709 hypothetical protein; SPTR: uncharacterized protein YP_004464581.1 COGs: COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); InterPro IPR008278: IPR004568: IPR002582; KEGG: geo:Geob_2943 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-[acyl-carrier-protein] synthase; TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase YP_004464582.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR003593: IPR007693: IPR007694: IPR007692; KEGG: cth:Cthe_2256 primary replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase; SPTR: Primary replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase YP_004464583.1 COGs: COG0359 Ribosomal protein L9; InterPro IPR020070: IPR020069: IPR020594; KEGG: ate:Athe_0881 50S ribosomal protein L9; PFAM: Ribosomal protein L9-like; SPTR: 50S ribosomal protein L9; TIGRFAM: ribosomal protein L9; PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_004464584.1 COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR001667: IPR003156: IPR014528: IPR000160; KEGG: amt:Amet_4770 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ domain protein; PFAM: DHH family; DHHA1 domain YP_004464585.1 InterPro IPR018710; KEGG: drm:Dred_3304 membrane protein-like protein; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Membrane protein-like protein; PFAM: Predicted membrane protein (DUF2232) YP_004464586.1 COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912: IPR018528; KEGG: cth:Cthe_2260 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain YP_004464587.1 COGs: COG0238 Ribosomal protein S18; InterPro IPR001648: IPR018275; KEGG: cno:NT01CX_0885 30S ribosomal protein S18; PFAM: ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: ribosomal protein S18; manually curated; PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_004464588.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424: IPR011344; KEGG: mta:Moth_0129 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004464589.1 COGs: COG0360 Ribosomal protein S6; InterPro IPR020814: IPR000529; KEGG: cno:NT01CX_0883 30S ribosomal protein S6; PFAM: Ribosomal protein S6, bacterial-like; SPTR: 30S ribosomal protein S6; TIGRFAM: ribosomal protein S6; PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_004464590.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001972: IPR001107; KEGG: cpo:COPRO5265_0367 erythrocyte band 7 integral membrane protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family YP_004464591.1 KEGG: tit:Thit_2193 hypothetical protein; SPTR: uncharacterized protein YP_004464593.1 KEGG: wbr:WGLp075 hypothetical protein; SPTR: MltC protein YP_004464594.1 KEGG: cpy:Cphy_1629 hypothetical protein; SPTR: uncharacterized protein YP_004464595.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593: IPR003439; KEGG: cpo:COPRO5265_1581 ABC-type transporter ATP-binding protein EcsA; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004464596.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: gym:GYMC10_5594 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004464597.1 KEGG: sti:Sthe_2080 hypothetical protein; SPTR: uncharacterized protein YP_004464598.1 KEGG: sno:Snov_2552 molybdate ABC transporter, inner membrane subunit; SPTR: Molybdate ABC transporter, inner membrane subunit YP_004464599.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR000838: IPR014284; KEGG: bts:Btus_0276 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004464600.1 InterPro IPR018486; KEGG: fre:Franean1_3992 transmembrane anti-sigma factor; SPTR: uncharacterized protein YP_004464601.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: ele:Elen_1458 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004464603.1 COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR003709; KEGG: cbi:CLJ_B1034 D-alanyl-D-alanine carboxypeptidase; PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: D-alanyl-D-alanine carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase YP_004464604.1 COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: nth:Nther_0598 VanW family protein; PFAM: VanW family protein; SPTR: VanW family protein; manually curated; PFAM: VanW like protein YP_004464605.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: tit:Thit_0150 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family YP_004464606.1 KEGG: hhe:HH0293 hypothetical protein; SPTR: uncharacterized protein YP_004464607.1 KEGG: tet:TTHERM_00188600 hypothetical protein; SPTR: uncharacterized protein YP_004464608.1 KEGG: phu:Phum_PHUM458070 hypothetical protein; SPTR: Glucose-6-phosphate isomerase YP_004464609.1 KEGG: nml:Namu_4260 hypothetical protein; SPTR: uncharacterized protein YP_004464610.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: mma:MM_2636 coenzyme F390 synthetase; PFAM: AMP-dependent synthetase and ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Coenzyme F390 synthetase; PFAM: AMP-binding enzyme YP_004464611.1 COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: mac:MA1726 indolepyruvate oxidoreductase subunit B; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Indolepyruvate oxidoreductase, subunit beta; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit YP_004464612.1 COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR002880: IPR011766: IPR017900: IPR017896: IPR 017721; KEGG: mma:MM_2634 pyruvate:ferredoxin oxidoreductase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: pyruvate:ferredoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit YP_004464613.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: ate:Athe_0575 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein; PFAM: CheW-like domain YP_004464614.1 COGs: COG1186 Protein chain release factor B; InterPro IPR005139: IPR000352: IPR020853: IPR004374; KEGG: cth:Cthe_0365 peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; SPTR: Peptide chain release factor 2; TIGRFAM: peptide chain release factor 2; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_004464615.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); InterPro IPR011115: IPR011130: IPR011116: IPR004027: IPR 000185: IPR020937: IPR014018; KEGG: csc:Csac_1325 preprotein translocase, SecA subunit; PFAM: SecA DEAD domain protein; SecA preprotein cross-linking region; SecA Wing and Scaffold; SEC-C motif domain protein; SPTR: Preprotein translocase, SecA subunit; TIGRFAM: preprotein translocase, SecA subunit; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit YP_004464616.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: gym:GYMC10_2567 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004464617.1 InterPro IPR001845; KEGG: cbt:CLH_1991 transcriptional regulator ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator ArsR family; PFAM: Bacterial regulatory protein, arsR family YP_004464618.1 COGs: COG5658 integral membrane protein; InterPro IPR012867; KEGG: tmt:Tmath_0494 protein of unknown function DUF1648; PFAM: protein of unknown function DUF1648; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1648) YP_004464619.1 COGs: COG2755 Lysophospholipase L1 and related esterase; InterPro IPR001087; KEGG: pmo:Pmob_0436 GDSL family lipase; PFAM: lipolytic protein G-D-S-L family; SPTR: Lipolytic protein G-D-S-L family; PFAM: GDSL-like Lipase/Acylhydrolase YP_004464620.1 KEGG: tmt:Tmath_0712 hypothetical protein; SPTR: uncharacterized protein; PFAM: transposase, YhgA-like YP_004464621.1 COGs: COG4392 membrane protein; InterPro IPR008407; KEGG: tpd:Teth39_1954 branched-chain amino acid transport; PFAM: branched-chain amino acid transport; SPTR: Branched-chain amino acid transport; PFAM: Branched-chain amino acid transport protein (AzlD) YP_004464622.1 COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: tmt:Tmath_0361 AzlC family protein; PFAM: AzlC family protein; SPTR: AzlC family protein; PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC YP_004464623.1 InterPro IPR007165; KEGG: tpd:Teth39_1403 hypothetical protein; PFAM: membrane protein of unknown function; SPTR: uncharacterized protein; PFAM: Membrane protein of unknown function YP_004464624.1 COGs: COG1501 Alpha-glucosidase 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: cbe:Cbei_0772 alpha-xylosidase YicI; PFAM: glycoside hydrolase 31; SPTR: Glycoside hydrolase 31; PFAM: Glycosyl hydrolases family 31 YP_004464625.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_0202 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464626.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_0201 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464627.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_0200 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464628.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR020449: IPR001789: IPR018060: IPR000005; KEGG: pjd:Pjdr2_0199 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464629.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR004358: IPR003660: IPR010559: IPR003594: IPR 005467; KEGG: pjd:Pjdr2_0198 histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464630.1 KEGG: mac:MA0146 methylcobalamin:coenzyme M methyltransferase; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464631.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_0925 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464632.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2778 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464633.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2780 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Domain of unknown function (DUF3502); Bacterial extracellular solute-binding protein YP_004464634.1 KEGG: ote:Oter_4338 uroporphyrinogen decarboxylase; SPTR: uncharacterized protein YP_004464635.1 COGs: COG1501 Alpha-glucosidase 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: bth:BT_3085 alpha-xylosidase; PFAM: glycoside hydrolase 31; SPTR: Alpha-xylosidase; PFAM: Glycosyl hydrolases family 31 YP_004464636.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR004358: IPR003594: IPR010559: IPR005467; KEGG: ate:Athe_2372 histidine kinase internal region; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464637.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR020449: IPR001789: IPR018060: IPR000005: IPR 018062; KEGG: cce:Ccel_2113 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464638.1 InterPro IPR006626: IPR003343: IPR006584: IPR011459: IPR 005084; KEGG: pjd:Pjdr2_0928 parallel beta-helix repeat protein; PFAM: Carbohydrate binding family 6; Ig domain protein group 2 domain protein; protein of unknown function DUF1565; SMART: cellulose binding type IV; Parallel beta-helix repeat; Ig domain protein group 2 domain protein; SPTR: Parallel beta-helix repeat protein; PFAM: Bacterial Ig-like domain (group 2); Carbohydrate binding module (family 6) YP_004464639.1 InterPro IPR003343: IPR006626; KEGG: pjd:Pjdr2_0928 parallel beta-helix repeat protein; PFAM: Ig domain protein group 2 domain protein; SMART: Ig domain protein group 2 domain protein; Parallel beta-helix repeat; SPTR: Parallel beta-helix repeat protein; PFAM: Bacterial Ig-like domain (group 2); TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; parallel beta-helix repeat (two copies) YP_004464640.1 KEGG: tpt:Tpet_1774 hypothetical protein; SPTR: uncharacterized protein YP_004464642.1 COGs: COG3345 Alpha-galactosidase; InterPro IPR002252: IPR000111; KEGG: tex:Teth514_1094 glycoside hydrolase, clan GH-D; PFAM: glycoside hydrolase clan GH-D; PRIAM: Alpha-galactosidase; SPTR: uncharacterized protein; PFAM: Melibiase YP_004464643.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dhd:Dhaf_2640 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464644.1 KEGG: kfl:Kfla_3906 hypothetical protein; SPTR: uncharacterized protein YP_004464645.1 COGs: COG3533 conserved hypothetical protein; InterPro IPR010905: IPR012878; KEGG: pdi:BDI_3334 hypothetical protein; PFAM: protein of unknown function DUF1680; glycosyl hydrolase 88; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase of unknown function (DUF1680) YP_004464646.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104: IPR006102: IPR006103; KEGG: gym:GYMC10_3042 beta-galactosidase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 2 TIM barrel; SPTR: Beta-galactosidase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain YP_004464647.1 KEGG: bfs:BF0767 methyltransferase; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464648.1 InterPro IPR006626: IPR006584: IPR003343: IPR005084; KEGG: pjd:Pjdr2_0928 parallel beta-helix repeat protein; PFAM: Carbohydrate binding family 6; Ig domain protein group 2 domain protein; SMART: cellulose binding type IV; Parallel beta-helix repeat; SPTR: Parallel beta-helix repeat protein; PFAM: Bacterial Ig-like domain (group 2); Carbohydrate binding module (family 6) YP_004464649.1 KEGG: pjd:Pjdr2_3732 extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1 YP_004464650.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: dth:DICTH_0039 transmembrane lipoprotein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Transmembrane lipoprotein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464651.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_1160 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464652.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR004358: IPR003594: IPR010559: IPR005467; KEGG: tex:Teth514_0398 histidine kinase internal region; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464653.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR020449: IPR001789: IPR018060: IPR000005; KEGG: pjd:Pjdr2_5068 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464654.1 KEGG: bur:Bcep18194_C6904 hypothetical protein; SPTR: deoxyribose mutarotase YP_004464655.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: ote:Oter_2886 uroporphyrinogen-III decarboxylase-like protein; SPTR: Uroporphyrinogen-III decarboxylase; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464656.1 COGs: COG2407 L-fucose isomerase and related protein; InterPro IPR012889: IPR015888; KEGG: bmq:BMQ_3645 hypothetical protein; PFAM: L-fucose isomerase-like-like; L-fucose isomerase _2 domain protein; SPTR: uncharacterized protein; PFAM: L-fucose isomerase, C-terminal domain YP_004464657.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: tex:Teth514_0395 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464658.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: tex:Teth514_0396 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464659.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tmt:Tmath_0508 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464660.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: tte:TTE1948 sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Sugar phosphate isomerases/epimerases; PFAM: AP endonuclease 2 C terminus; Xylose isomerase-like TIM barrel YP_004464661.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: dtu:Dtur_0484 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: aldehyde-dehydrogenase-like protein y4uC; PFAM: Aldehyde dehydrogenase YP_004464662.1 COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: dtu:Dtur_0481 galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; PRIAM: Galactarate dehydratase; SPTR: Galactarate dehydratase; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus YP_004464663.1 InterPro IPR013974; KEGG: sto:ST2559 hypothetical protein; PFAM: SAF domain protein; SPTR: uncharacterized protein ST2559; PFAM: SAF domain YP_004464664.1 COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: mta:Moth_1926 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088) YP_004464665.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: tit:Thit_1576 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004464666.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: cno:NT01CX_1781 lipopolysaccharide biosynthesis protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Lipopolysaccharide biosynthesis protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004464668.1 COGs: COG2855 membrane protein; InterPro IPR018383; KEGG: nth:Nther_2578 hypothetical protein; PFAM: Uncharacterised protein family UPF0324; SPTR: uncharacterized protein; PFAM: Conserved hypothetical protein 698; TIGRFAM: conserved hypothetical integral membrane protein YP_004464669.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase 4 of glycosyl hydrolase; InterPro IPR001088: IPR019802; KEGG: bha:BH2228 melibiase (alpha-galactosidase); PFAM: glycoside hydrolase 4; SPTR: Melibiase (Alpha-galactosidase); PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004464670.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: csc:Csac_0695 ROK family protein; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family YP_004464671.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: cpo:COPRO5265_0009 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004464672.1 KEGG: cpo:COPRO5265_0010 hypothetical protein; SPTR: uncharacterized protein YP_004464673.1 KEGG: pct:PC1_0413 methyl-accepting chemotaxis sensory transducer; SPTR: uncharacterized protein YP_004464674.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611: IPR002173: IPR017583; KEGG: csc:Csac_2441 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase YP_004464675.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR002139: IPR011611: IPR002173: IPR011877; KEGG: psp:PSPPH_2129 ribokinase; PFAM: PfkB domain protein; SPTR: Ribokinase; TIGRFAM: ribokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase YP_004464676.1 KEGG: nwa:Nwat_1322 hypothetical protein; SPTR: uncharacterized protein YP_004464677.1 COGs: COG1811 Uncharacterized membrane protein possible Na+ channel or pump; InterPro IPR007563; KEGG: amt:Amet_0832 hypothetical protein; PFAM: protein of unknown function DUF554; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF554) YP_004464678.1 COGs: COG1544 Ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: cth:Cthe_2875 sigma 54 modulation protein / SSU ribosomal protein S30P; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; SPTR: Sigma 54 modulation protein / SSU ribosomal protein S30P; TIGRFAM: ribosomal subunit interface protein; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_004464679.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: cno:NT01CX_0934 ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter; manually curated; PFAM: ABC transporter YP_004464680.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515: IPR010065; KEGG: eel:EUBELI_01698 polar amino acid transport system permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Polar amino acid transport system permease; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family YP_004464681.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: tex:Teth514_0468 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004464682.1 KEGG: ate:Athe_1830 hypothetical protein; SPTR: uncharacterized protein YP_004464683.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: cbb:CLD_3055 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen-III decarboxylase-like protein; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family YP_004464684.1 COGs: COG0442 Prolyl-tRNA synthetase; InterPro IPR002316: IPR002314: IPR007214: IPR004154: IPR 006195: IPR004500; KEGG: tmt:Tmath_1944 prolyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); YbaK/prolyl-tRNA synthetase associated region; Anticodon-binding domain protein; SPTR: Prolyl-tRNA synthetase; TIGRFAM: prolyl-tRNA synthetase; PFAM: YbaK / prolyl-tRNA synthetases associated domain; Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II YP_004464685.1 COGs: COG1345 Flagellar capping protein; InterPro IPR003481: IPR010809; KEGG: dau:Daud_1783 flagellar hook-associated 2 domain-containing protein; PFAM: flagellar hook-associated 2 domain-containing protein; flagellar hook-associated protein 2 domain-containing protein; SPTR: Flagellar hook-associated 2 domain protein; PFAM: Flagellar hook-associated protein 2 C-terminus YP_004464686.1 COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: cce:Ccel_0106 flagellar protein FliS; PFAM: flagellar protein FliS; SPTR: Flagellar protein FliS; TIGRFAM: flagellar protein FliS; PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS YP_004464687.1 KEGG: bfo:BRAFLDRAFT_113850 hypothetical protein; SPTR: PhoU family YP_004464688.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: cpy:Cphy_3277 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family YP_004464689.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: cpy:Cphy_3278 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: Monosaccharide-transporting ATPase; PFAM: Branched-chain amino acid transport system / permease component YP_004464690.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871: IPR015861; KEGG: cpy:Cphy_3279 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; manually curated; PFAM: ABC transporter YP_004464691.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439; KEGG: cpy:Cphy_3280 ABC-type sugar transport system ATPase component-like protein; SPTR: ABC-type sugar transport system ATPase component-like protein YP_004464692.1 COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR010559: IPR003594; KEGG: cpy:Cphy_3281 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004464693.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR020449: IPR001789: IPR018060: IPR000005: IPR 018062; KEGG: cpy:Cphy_3282 two component AraC family transcriptional regulator; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464694.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR010061; KEGG: str:Sterm_4016 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase YP_004464695.1 COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: kol:Kole_0990 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family YP_004464696.1 COGs: COG0176 Transaldolase; InterPro IPR001585; KEGG: pac:PPA0454 transaldolase; PFAM: Transaldolase; SPTR: uncharacterized protein; PFAM: Transaldolase YP_004464697.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: str:Sterm_4013 myo-inosose-2 dehydratase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Inosose dehydratase (2-keto-myo-inositol dehydratase); PFAM: Xylose isomerase-like TIM barrel YP_004464698.1 COGs: COG3962 Acetolactate synthase; InterPro IPR012001: IPR012000: IPR011766: IPR000399; KEGG: gka:GK1891 myo-inositol catabolism protein (thiamine pyrophosphate-requiring enzyme); PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Probable malonic semialdehyde oxidative decarboxylase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004464699.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: hsm:HSM_0435 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004464700.1 KEGG: cce:Ccel_1446 hypothetical protein; SPTR: uncharacterized protein YP_004464701.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: tex:Teth514_0161 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family YP_004464702.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: mka:MK0426 hypothetical protein; PFAM: amidohydrolase 2; SPTR: uncharacterized protein; PFAM: Amidohydrolase YP_004464703.1 KEGG: aca:ACP_3040 O-glycosyl hydrolase, family 30; SPTR: O-Glycosyl hydrolase, family 30 YP_004464704.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_4183 ABC-type sugar transport system periplasmic component-like protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transport system periplasmic component-like protein; PFAM: Bacterial extracellular solute-binding protein YP_004464705.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cpy:Cphy_0930 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464706.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_2821 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464707.1 COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: dhd:Dhaf_3404 GntR domain protein; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004464708.1 COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR017900: IPR017896; KEGG: nth:Nther_2897 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; Domain of unknown function (DUF362) YP_004464709.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: dtu:Dtur_1645 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004464710.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: pfu:PF0354 hypothetical protein; PFAM: LmbE family protein; SPTR: LmbE family protein; PFAM: GlcNAc-PI de-N-acetylase YP_004464711.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701: IPR018043; KEGG: gym:GYMC10_0496 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004464713.1 InterPro IPR018958; KEGG: bce:BC3030 hypothetical protein; PFAM: Cell wall assembly/cell proliferation coordinating protein, KNR4-like; SPTR: uncharacterized protein; PFAM: SMI1 / KNR4 family YP_004464714.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: dsy:DSY4108 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein YP_004464715.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cce:Ccel_1254 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464716.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4465 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464717.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_4270 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464718.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: clj:CLJU_c30300 uroporphyrinogen decarboxylase-like protein; SPTR: Uroporphyrinogen-III decarboxylase-like protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464719.1 COGs: COG5598 Trimethylamine:corrinoid methyltransferase; InterPro IPR010426; KEGG: dat:HRM2_44210 MttB10; PFAM: trimethylamine methyltransferase; SPTR: MttB10; PFAM: Trimethylamine methyltransferase (MTTB) YP_004464720.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: mth:MTH171 glucosamine--fructose-6-phosphate aminotransferase; PFAM: sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: SIS domain YP_004464721.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: rpa:RPA0378 alpha-D-galactoside galactohydrolase; PFAM: glycoside hydrolase 4; SPTR: alpha-D-galactoside galactohydrolase; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004464722.1 KEGG: caa:Caka_2762 hypothetical protein; SPTR: uncharacterized protein YP_004464723.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tpd:Teth39_2053 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family YP_004464724.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125; KEGG: bcl:ABC0477 hypothetical protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: uncharacterized protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004464725.1 COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR000573: IPR011824: IPR011827; KEGG: clj:CLJU_c09070 3-isopropylmalate dehydratase small subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_004464726.1 COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR001030: IPR011826: IPR018136: IPR006251: IPR 011823; KEGG: cth:Cthe_2211 3-isopropylmalate dehydratase large subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: 3-isopropylmalate dehydratase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase; 3-isopropylmalate dehydratase; PFAM: Aconitase (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase YP_004464727.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891: IPR013709: IPR002034: IPR005675; KEGG: cth:Cthe_2519 alpha-isopropylmalate/homocitrate synthase transferase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase YP_004464728.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891: IPR013709: IPR002034: IPR005671; KEGG: ate:Athe_0505 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase, bacterial type YP_004464729.1 COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013116: IPR000506: IPR013023; KEGG: csc:Csac_1144 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase catalytic domain-containing protein; acetohydroxy acid isomeroreductase; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase YP_004464730.1 COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912: IPR019455: IPR004789; KEGG: cth:Cthe_2517 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: Acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit YP_004464731.1 InterPro IPR001584; KEGG: tjr:TherJR_2621 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain YP_004464732.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660: IPR004089: IPR004010; KEGG: tjr:TherJR_0184 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004464733.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: chy:CHY_1706 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Transcriptional regulator, MerR family; PFAM: MerR family regulatory protein; MerR, DNA binding YP_004464734.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471: IPR001395; KEGG: str:Sterm_3237 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase YP_004464735.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: dhd:Dhaf_3921 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004464736.1 COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: mba:Mbar_A0776 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004464737.1 COGs: COG0599 gamma-carboxymuconolactone decarboxylase subunit; InterPro IPR003779; KEGG: bfr:BF1907 hypothetical protein; PFAM: Carboxymuconolactone decarboxylase; SPTR: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; PFAM: Carboxymuconolactone decarboxylase YP_004464738.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: pdi:BDI_2172 flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavoredoxin; PFAM: Flavin reductase like domain YP_004464739.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: dae:Dtox_4284 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family YP_004464740.1 COGs: COG0701 permease; InterPro IPR005524; KEGG: pmo:Pmob_0731 permease; PFAM: permease; SPTR: Permease; PFAM: Predicted permease YP_004464741.1 InterPro IPR017900: IPR017896; KEGG: dsy:DSY4677 hypothetical protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Protein of unknown function (DUF2703) YP_004464742.1 InterPro IPR005243; KEGG: dae:Dtox_4282 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2 YP_004464743.1 InterPro IPR007419; KEGG: pmo:Pmob_0435 mercuric transport protein periplasmic component; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: uncharacterized protein; PFAM: BFD-like [2Fe-2S] binding domain YP_004464744.1 COGs: COG0597 Lipoprotein signal peptidase; InterPro IPR001872; KEGG: pmo:Pmob_0434 lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: lipoprotein signal peptidase; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_004464745.1 COGs: COG2217 Cation transport ATPase; InterPro IPR001757: IPR001366: IPR006121: IPR008250: IPR 005834: IPR018303: IPR006404: IPR006416; KEGG: tex:Teth514_1276 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004464746.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845: IPR018334; KEGG: pmo:Pmob_0432 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family YP_004464747.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119: IPR011109; KEGG: pmo:Pmob_0430 resolvase domain-containing protein; PFAM: Resolvase domain; Recombinase; SPTR: Resolvase domain; PFAM: Recombinase; Resolvase, N terminal domain YP_004464748.1 InterPro IPR011109; KEGG: cth:Cthe_1608 recombinase; PFAM: Recombinase; SPTR: Recombinase; manually curated YP_004464749.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119: IPR011109; KEGG: cth:Cthe_1609 recombinase; PFAM: Resolvase domain; Recombinase; SPTR: Recombinase; PFAM: Recombinase; Resolvase, N terminal domain YP_004464750.1 KEGG: pmo:Pmob_0427 hypothetical protein; SPTR: uncharacterized protein YP_004464751.1 InterPro IPR002502: IPR018392: IPR002482; KEGG: pmo:Pmob_0425 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; N-acetylmuramoyl-L-alanine amidase 2; SMART: N-acetylmuramoyl-L-alanine amidase 2; Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding lysin domain protein; PFAM: N-acetylmuramoyl-L-alanine amidase; LysM domain YP_004464752.1 COGs: COG4824 Phage-related holin (Lysis protein); InterPro IPR006480; KEGG: cth:Cthe_1612 toxin secretion/phage lysis holin; PFAM: Holin toxin secretion/phage lysis; SPTR: Toxin secretion/phage lysis holin; TIGRFAM: toxin secretion/phage lysis holin; PFAM: Holin family; TIGRFAM: toxin secretion/phage lysis holin YP_004464753.1 COGs: COG3858 glycosyl hydrolase; InterPro IPR010916; KEGG: cth:Cthe_1613 glycosyl hydrolase-like protein; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolases family 18 YP_004464754.1 KEGG: cth:Cthe_1614 hypothetical protein; SPTR: uncharacterized protein YP_004464755.1 KEGG: cth:Cthe_1615 hypothetical protein; SPTR: uncharacterized protein YP_004464756.1 COGs: COG4926 Phage-related protein; InterPro IPR000634: IPR007119; KEGG: cth:Cthe_1616 phage minor structural protein; SPTR: Phage minor structural protein; TIGRFAM: phage minor structural protein; PFAM: Protein of unknown function (DUF1142); TIGRFAM: phage minor structural protein, N-terminal region YP_004464757.1 COGs: COG4722 Phage-related protein; InterPro IPR006520; KEGG: cth:Cthe_1617 phage tail component; SPTR: Phage tail component; TIGRFAM: phage tail component; PFAM: Phage tail protein; TIGRFAM: phage tail component, N-terminal domain YP_004464758.1 COGs: COG5412 Phage-related protein; KEGG: cce:Ccel_2825 hypothetical protein; SPTR: Phage-related protein-like protein YP_004464759.1 KEGG: cth:Cthe_1621 hypothetical protein; SPTR: uncharacterized protein YP_004464760.1 KEGG: cth:Cthe_1622 hypothetical protein; SPTR: uncharacterized protein YP_004464761.1 InterPro IPR006490; KEGG: cth:Cthe_1623 phi13 family phage major tail protein; SPTR: Phage major tail protein, phi13 family; TIGRFAM: phage major tail protein, phi13 family; TIGRFAM: phage major tail protein, phi13 family YP_004464762.1 KEGG: cth:Cthe_1624 hypothetical protein; SPTR: uncharacterized protein YP_004464763.1 InterPro IPR010064: IPR006967; KEGG: cth:Cthe_1625 HK97 family phage protein; PFAM: protein of unknown function DUF646 phage head/tail component; SPTR: Phage protein, HK97 gp10 family; TIGRFAM: phage protein, HK97 gp10 family; PFAM: Bacteriophage protein of unknown function (DUF646); TIGRFAM: phage protein, HK97 gp10 family YP_004464764.1 InterPro IPR008767; KEGG: cth:Cthe_1626 phage head-tail adaptor, SPTR: head-tail adaptor protein; TIGRFAM: phage head-tail adaptor; manually curated; PFAM: Phage head-tail joining protein; TIGRFAM: phage head-tail adaptor, , SPP1 family YP_004464765.1 InterPro IPR008265; KEGG: cth:Cthe_1627 uncharacterized phage protein; SPTR: Uncharacterized phage protein; PFAM: Phage QLRG family, DNA packaging; TIGRFAM: uncharacterized phage protein (possible DNA packaging) YP_004464766.1 COGs: COG4653 phage phi-C31 gp36 major capsid-like protein; InterPro IPR006444; KEGG: cth:Cthe_1628 HK97 family phage major capsid protein; SPTR: Phage major capsid protein, HK97 family; TIGRFAM: phage major capsid protein, HK97 family; PFAM: Phage capsid family; TIGRFAM: phage major capsid protein, HK97 family YP_004464767.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: cth:Cthe_1629 peptidase S14, ClpP; PFAM: peptidase S14 ClpP; SPTR: ATP-dependent Clp protease proteolytic subunit; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_004464768.1 COGs: COG4695 Phage-related protein; InterPro IPR006944: IPR006427; KEGG: cth:Cthe_1630 HK97 family phage portal protein; PFAM: portal protein; SPTR: Phage portal protein, HK97 family; TIGRFAM: phage portal protein, HK97 family; PFAM: Phage portal protein; TIGRFAM: phage portal protein, HK97 family YP_004464769.1 COGs: COG4626 Phage terminase-like protein large subunit; InterPro IPR005021; KEGG: hmo:HM1_2883 phage terminase, large subunit, PFAM: Terminase; SPTR: Terminase; PFAM: Phage Terminase YP_004464770.1 KEGG: cth:Cthe_1633 hypothetical protein; SPTR: uncharacterized protein YP_004464771.1 InterPro IPR009288; KEGG: cth:Cthe_1634 hypothetical protein; PFAM: AIG2 family protein; SPTR: AIG2 family protein; PFAM: AIG2-like family YP_004464772.1 KEGG: cth:Cthe_1635 hypothetical protein; SPTR: uncharacterized protein; PFAM: amidoligase enzyme YP_004464773.1 KEGG: cth:Cthe_1636 hypothetical protein; SPTR: uncharacterized protein YP_004464774.1 KEGG: hmo:HM1_2888 hypothetical protein; SPTR: uncharacterized protein YP_004464775.1 KEGG: cth:Cthe_1637 virulence-related protein; SPTR: Virulence-related protein YP_004464776.1 COGs: COG0863 DNA modification methylase; InterPro IPR003115: IPR002941: IPR002052: IPR001091: IPR 015840; KEGG: cth:Cthe_1638 ParB-like nuclease; PFAM: ParB domain protein nuclease; DNA methylase N-4/N-6 domain protein; SMART: ParB domain protein nuclease; SPTR: ParB-like nuclease; PFAM: DNA methylase; ParB-like nuclease domain YP_004464777.1 COGs: COG0863 DNA modification methylase; InterPro IPR003115: IPR002941: IPR017985: IPR000909: IPR 001091: IPR015840; KEGG: cth:Cthe_1639 DNA methylase N-4/N-6; PFAM: DNA methylase N-4/N-6 domain protein; ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: DNA methylase N-4/N-6; PFAM: DNA methylase; ParB-like nuclease domain YP_004464778.1 KEGG: bse:Bsel_3023 hypothetical protein; SPTR: uncharacterized protein YP_004464779.1 KEGG: cth:Cthe_1640 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage terminase, small subunit YP_004464780.1 InterPro IPR002711: IPR003615; KEGG: ckr:CKR_2350 hypothetical protein; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: uncharacterized protein; manually curated; PFAM: HNH endonuclease YP_004464781.1 KEGG: hmo:HM1_2944 hypothetical protein; SPTR: uncharacterized protein YP_004464782.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR000330: IPR014021: IPR014001; KEGG: hmo:HM1_2943 phage-associated helicase, SNF2 family; PFAM: SNF2-related protein; SMART: DEAD-like helicase; SPTR: Phage-associated helicase, snf2 family; PFAM: SNF2 family N-terminal domain YP_004464783.1 InterPro IPR014883; KEGG: det:DET1097 hypothetical protein; PFAM: VRR-NUC domain-containing protein; SPTR: uncharacterized protein; PFAM: VRR-NUC domain YP_004464784.1 COGs: COG5545 P-loop ATPase and inactivated derivatives; InterPro IPR007936; KEGG: tex:Teth514_1237 virulence-associated E family protein; PFAM: virulence-associated E family protein; SPTR: Virulence-associated E family protein; PFAM: Virulence-associated protein E; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_004464785.1 KEGG: tex:Teth514_1236 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004464786.1 KEGG: rca:Rcas_0567 hypothetical protein; SPTR: uncharacterized protein YP_004464787.1 COGs: COG3617 Prophage antirepressor; InterPro IPR003497: IPR005039; KEGG: tex:Teth514_1235 prophage antirepressor; PFAM: phage antirepressor protein; BRO domain protein; SPTR: Prophage antirepressor; PFAM: BRO family, N-terminal domain; Phage antirepressor protein KilAC domain YP_004464788.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterPro IPR001098: IPR013838: IPR019760; KEGG: tex:Teth514_1234 DNA-directed DNA polymerase; PFAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase; SPTR: DNA polymerase I; PFAM: DNA polymerase A YP_004464789.1 KEGG: tex:Teth514_1233 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2815) YP_004464790.1 InterPro IPR008162; KEGG: tex:Teth514_1232 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2800) YP_004464791.1 KEGG: tex:Teth514_1231 hypothetical protein; SPTR: uncharacterized protein YP_004464792.1 KEGG: clj:CLJU_c03350 hypothetical protein; SPTR: uncharacterized protein YP_004464793.1 InterPro IPR013249; KEGG: tex:Teth514_1230 ECF subfamily RNA polymerase sigma-24 factor; PFAM: Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70, region 4 YP_004464794.1 KEGG: amt:Amet_4054 hypothetical protein; SPTR: uncharacterized protein YP_004464795.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: amt:Amet_4055 hypothetical protein; PFAM: protein of unknown function DUF45; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF45 YP_004464796.1 COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409: IPR006935: IPR014021: IPR014001: IPR 004473; KEGG: amt:Amet_4056 HsdR family type I site-specific deoxyribonuclease; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: Type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family YP_004464797.1 COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: dol:Dole_0249 restriction modification system DNA specificity subunit; PFAM: restriction modification system DNA specificity domain; SPTR: Type I restriction-modification enzyme S subunit; PFAM: Type I restriction modification DNA specificity domain YP_004464798.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356: IPR002052: IPR002296; KEGG: amt:Amet_4058 N-6 DNA methylase; PFAM: N-6 DNA methylase; SPTR: N-6 DNA methylase; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004464799.1 InterPro IPR010093; KEGG: eel:EUBELI_01532 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004464800.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792: IPR000241: IPR010280: IPR001566; KEGG: tpd:Teth39_0686 RNA methyltransferase; PFAM: deoxyribonuclease/rho motif-related TRAM; RNA methylase; SPTR: RNA methyltransferase, TrmA family; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: tRNA (Uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA YP_004464801.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: tjr:TherJR_1866 peptidase U32; PFAM: peptidase U32; SPTR: Peptidase U32; PFAM: Collagenase; Peptidase U32 YP_004464802.1 KEGG: dhd:Dhaf_0672 hypothetical protein; SPTR: uncharacterized protein YP_004464803.1 KEGG: ote:Oter_2886 uroporphyrinogen-III decarboxylase-like protein; SPTR: Uroporphyrinogen-III decarboxylase-like protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464804.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000524: IPR001761; KEGG: tmt:Tmath_1684 transcriptional regulator, GntR family with LacI sensor; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; family YP_004464805.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: cth:Cthe_2785 MtaA/CmuA family methyltransferase; SPTR: Methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464806.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: tpd:Teth39_0526 LmbE family protein; PFAM: LmbE family protein; SPTR: LmbE family protein; PFAM: GlcNAc-PI de-N-acetylase YP_004464807.1 InterPro IPR000182; KEGG: dge:Dgeo_0737 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004464808.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: clj:CLJU_c39510 two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004464809.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: cdl:CDR20291_0446 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004464810.1 InterPro IPR013026; KEGG: nth:Nther_0252 response regulator receiver protein; SPTR: Response regulator receiver protein YP_004464811.1 KEGG: csc:Csac_0148 hypothetical protein; SPTR: uncharacterized protein YP_004464812.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: ate:Athe_0240 cation transporter; PFAM: cation transporter; SPTR: Cation transporter; PFAM: Cation transport protein YP_004464814.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037: IPR006036; KEGG: cce:Ccel_2082 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain; TrkA-C domain YP_004464815.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037: IPR006036; KEGG: csc:Csac_0151 TrkA domain-containing protein; PFAM: TrkA-N domain protein; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain YP_004464816.1 KEGG: mma:MM_1677 hypothetical protein; SPTR: uncharacterized protein YP_004464817.1 KEGG: cac:CA_C0242 permease; SPTR: uncharacterized protein YP_004464818.1 KEGG: swo:Swol_1705 hypothetical protein; SPTR: uncharacterized protein YP_004464819.1 KEGG: fjo:Fjoh_2543 hypothetical protein; SPTR: uncharacterized protein YP_004464820.1 KEGG: tet:TTHERM_00354670 hypothetical protein; SPTR: uncharacterized protein YP_004464821.1 KEGG: amt:Amet_0466 hypothetical protein; SPTR: uncharacterized protein YP_004464822.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR000330: IPR001650: IPR014021: IPR014001; KEGG: cyn:Cyan7425_2099 helicase domain protein; PFAM: helicase domain protein; SNF2-related protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004464823.1 COGs: COG1743 Adenine-specific DNA methylase containing a Zn-ribbon; InterPro IPR009537; KEGG: ttr:Tter_2145 protein of unknown function DUF1156; PFAM: protein of unknown function DUF1156; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1156) YP_004464824.1 COGs: COG1483 ATPase (AAA+ superfamily); KEGG: dhd:Dhaf_0639 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF499) YP_004464825.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: ele:Elen_1600 bacteriophage N4 adsorption protein B; SPTR: General secretory system II protein E domain protein YP_004464826.1 InterPro IPR010093; KEGG: dae:Dtox_3698 DNA binding domain protein, excisionase; SPTR: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004464827.1 KEGG: tex:Teth514_0737 hypothetical protein; SPTR: uncharacterized protein YP_004464828.1 KEGG: tex:Teth514_0738 type IV secretory pathway VirD4 components-like protein; SPTR: Type IV secretory pathway VirD4 components-like protein; PFAM: Type IV secretion-system coupling protein DNA-binding domain YP_004464829.1 InterPro IPR015330: IPR014820; KEGG: adg:Adeg_2001 bifunctional DNA primase/polymerase; PFAM: Bifunctional DNA primase/polymerase; Primase 1; SPTR: Bifunctional DNA primase/polymerase; PFAM: Bifunctional DNA primase/polymerase, N-terminal; Primase C terminal 1 (PriCT-1) YP_004464830.1 KEGG: tpd:Teth39_0089 hypothetical protein; SPTR: uncharacterized protein YP_004464831.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104: IPR017441; KEGG: dae:Dtox_3730 integrase; PFAM: integrase; SPTR: Integrase; PFAM: Phage integrase YP_004464832.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR006199; KEGG: ate:Athe_2440 transcriptional repressor, LexA family; PFAM: LexA DNA-binding domain protein; SPTR: Transcriptional repressor, LexA family; PFAM: LexA DNA binding domain YP_004464833.1 COGs: COG4299 conserved hypothetical protein; KEGG: sli:Slin_5410 protein of unknown function DUF2261, transmembrane; PRIAM: Heparan-alpha-glucosaminide N-acetyltransferase; SPTR: uncharacterized protein YP_004464834.1 InterPro IPR018392: IPR002482; KEGG: slp:Slip_1129 peptidoglycan-binding lysin domain protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding lysin domain protein; PFAM: LysM domain YP_004464835.1 KEGG: tro:trd_0997 hypothetical protein; SPTR: uncharacterized protein YP_004464837.1 KEGG: bcy:Bcer98_2582 holin; SPTR: Holin YP_004464838.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508: IPR007730; KEGG: hmo:HM1_2806 N-acetylmuramoyl-L-alanine amidase, PFAM: cell wall hydrolase/autolysin; Sporulation domain-containing protein; PRIAM: N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-l-alanine amidase, ; PFAM: N-acetylmuramoyl-L-alanine amidase; Sporulation related domain; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD YP_004464839.1 KEGG: pno:SNOG_14901 hypothetical protein; SPTR: uncharacterized protein YP_004464840.1 COGs: COG3858 glycosyl hydrolase; InterPro IPR001223: IPR011583; KEGG: cce:Ccel_2820 hypothetical protein; PFAM: glycoside hydrolase 18; SMART: chitinase II; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolases family 18 YP_004464841.1 KEGG: tit:Thit_1373 hypothetical protein; SPTR: uncharacterized protein YP_004464842.1 KEGG: tit:Thit_1374 hypothetical protein; SPTR: uncharacterized protein YP_004464843.1 COGs: COG4926 Phage-related protein; InterPro IPR007119; KEGG: cth:Cthe_1616 phage minor structural protein; SPTR: Phage minor structural protein; TIGRFAM: phage minor structural protein; PFAM: Protein of unknown function (DUF1142); TIGRFAM: phage minor structural protein, N-terminal region YP_004464844.1 KEGG: tbr:Tb927.6.2870 hypothetical protein; SPTR: Ca2+-binding protein YP_004464845.1 KEGG: tit:Thit_1377 phage tail component; SPTR: Phage tail component; PFAM: Phage tail protein; TIGRFAM: phage tail component, N-terminal domain YP_004464846.1 COGs: COG5280 Phage-related minor tail protein; InterPro IPR010090; KEGG: afl:Aflv_0673 phage-related tail protein; PFAM: tail tape measure protein TP901 core region; SPTR: Phage-related tail protein; TIGRFAM: phage tail tape measure protein, TP901 family; PFAM: Phage-related minor tail protein; TMP repeat; TIGRFAM: phage tail tape measure protein, TP901 family, core region YP_004464847.1 SPTR: Transposition protein YP_004464848.1 KEGG: pth:PTH_2180 hypothetical protein; SPTR: uncharacterized protein YP_004464849.1 KEGG: chy:CHY_1665 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage major tail protein 2; TIGRFAM: phage major tail protein, TP901-1 family YP_004464850.1 KEGG: dvl:Dvul_0864 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3168) YP_004464851.1 InterPro IPR010064; KEGG: gyc:GYMC61_0631 phage protein, HK97 GP10 family; SPTR: Phage protein, HK97 gp10 family; TIGRFAM: phage protein, HK97 gp10 family; PFAM: Bacteriophage protein of unknown function (DUF646); TIGRFAM: phage protein, HK97 gp10 family YP_004464852.1 COGs: COG5614 Bacteriophage head-tail adaptor; InterPro IPR008767; KEGG: dvl:Dvul_0865 phage head-tail adaptor, SPTR: Phage head-tail adaptor, ; TIGRFAM: phage head-tail adaptor; PFAM: Phage head-tail joining protein; TIGRFAM: phage head-tail adaptor, , SPP1 family YP_004464853.1 InterPro IPR011738; KEGG: pla:Plav_0908 phiE125 gp8 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage QLRG family, DNA packaging; TIGRFAM: phage conserved hypothetical protein, phiE125 gp8 family; uncharacterized phage protein (possible DNA packaging) YP_004464854.1 KEGG: mno:Mnod_7328 hypothetical protein YP_004464855.1 COGs: COG4653 phage phi-C31 gp36 major capsid-like protein; InterPro IPR006444; KEGG: hmo:HM1_2880 phage major capsid protein, hk97 family; SPTR: Phage major capsid protein, HK97 family; TIGRFAM: phage major capsid protein, HK97 family; PFAM: Phage capsid family; TIGRFAM: phage major capsid protein, HK97 family YP_004464856.1 COGs: COG3740 Phage head maturation protease; InterPro IPR006433; KEGG: glo:Glov_1679 phage prohead protease, HK97 family; PFAM: peptidase U35 phage prohead HK97; SPTR: Phage prohead protease, HK97 family; TIGRFAM: phage prohead protease, HK97 family; PFAM: Caudovirus prohead protease; TIGRFAM: phage prohead protease, HK97 family YP_004464857.1 KEGG: chy:CHY_2149 hypothetical protein; SPTR: Conserved domain protein YP_004464858.1 COGs: COG4695 Phage-related protein; InterPro IPR006944: IPR006528: IPR006427; KEGG: hmo:HM1_2882 phage portal protein, hk97 family; PFAM: portal protein; head morphogenesis protein SPP1 gp7; SPTR: Phage portal protein, hk97 family; TIGRFAM: phage portal protein, HK97 family; PFAM: Phage portal protein; Phage Mu protein F like protein; TIGRFAM: phage portal protein, HK97 family YP_004464859.1 COGs: COG3747 Phage terminase small subunit; InterPro IPR006448; KEGG: clj:CLJU_c03520 phage terminasesmall subunit; SPTR: Phage terminase, small subunit, , P27 family; TIGRFAM: phage terminase, small subunit, , P27 family; PFAM: Phage terminase, small subunit; TIGRFAM: phage terminase, small subunit, , P27 family YP_004464860.1 InterPro IPR002711: IPR003615; KEGG: dvu:DVU1505 holin, PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease; manually curated; PFAM: HNH endonuclease YP_004464861.1 KEGG: spv:SPH_1255 hypothetical protein; SPTR: uncharacterized protein YP_004464862.1 InterPro IPR013249; KEGG: psp:PSPPH_1175 RNA polymerase sigma-70 family protein; PFAM: Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma-70 family protein; PFAM: Sigma-70, region 4 YP_004464863.1 KEGG: mst:Msp_0171 leucyl-tRNA synthetase; SPTR: LeuS YP_004464864.1 InterPro IPR008822; KEGG: drm:Dred_0504 endodeoxyribonuclease RusA; PFAM: endodeoxyribonuclease RusA; SPTR: Endodeoxyribonuclease RusA; PFAM: Endodeoxyribonuclease RusA YP_004464865.1 KEGG: psl:Psta_0302 resolvase domain protein YP_004464866.1 KEGG: cgr:CAGL0H05929g hypothetical protein YP_004464867.1 KEGG: cce:Ccel_1844 hypothetical protein; SPTR: uncharacterized protein YP_004464868.1 COGs: COG1484 DNA replication protein; InterPro IPR002611: IPR003593; KEGG: amt:Amet_2601 IstB ATP binding domain-containing protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004464869.1 InterPro IPR006497; KEGG: pay:PAU_03574 phage replication protein O; PFAM: replication protein O domain protein; SPTR: uncharacterized protein; TIGRFAM: phage replication protein O; PFAM: Bacteriophage replication protein O; TIGRFAM: phage replication protein O, N-terminal domain YP_004464870.1 KEGG: swo:Swol_2264 hypothetical protein; SPTR: uncharacterized protein YP_004464871.1 KEGG: ere:EUBREC_2135 hypothetical protein; SPTR: uncharacterized protein YP_004464872.1 KEGG: tet:TTHERM_00497680 hypothetical protein; SPTR: uncharacterized protein DKFZp434J052 YP_004464873.1 InterPro IPR010093; KEGG: cth:Cthe_2463 DNA binding domain-containing protein; SPTR: DNA binding domain, excisionase; TIGRFAM: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004464874.1 KEGG: dwi:Dwil_GK13056 GK13056 gene product from transcript GK13056-RA; SPTR: DNA gyrase, B subunit YP_004464875.1 InterPro IPR001387; KEGG: amt:Amet_2116 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix YP_004464876.1 InterPro IPR001387; KEGG: tit:Thit_1413 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix YP_004464877.1 KEGG: dae:Dtox_3689 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF955) YP_004464878.1 COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR013520: IPR006055: IPR006054; KEGG: ckr:CKR_P20 DNA polymerase III subunit epsilon; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family YP_004464879.1 KEGG: cpi:Cpin_3875 hypothetical protein; SPTR: uncharacterized protein YP_004464880.1 KEGG: ace:Acel_1105 amino acid permease-associated region; SPTR: uncharacterized protein YP_004464881.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: tpd:Teth39_2246 phage integrase; PFAM: integrase; SPTR: Phage integrase; PFAM: Phage integrase YP_004464882.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018062: IPR018060: IPR020449; KEGG: gym:GYMC10_4531 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464883.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tmt:Tmath_0244 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464884.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: tmt:Tmath_0243 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464885.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: tit:Thit_0185 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464886.1 COGs: COG1312 D-mannonate dehydratase; InterPro IPR004628; KEGG: amt:Amet_1292 mannonate dehydratase; PFAM: Mannonate dehydratase; PRIAM: Mannonate dehydratase; SPTR: Mannonate dehydratase; TIGRFAM: mannonate dehydratase; PFAM: D-mannonate dehydratase (UxuA); TIGRFAM: mannonate dehydratase YP_004464887.1 KEGG: cbi:CLJ_B3976 hypothetical protein; SPTR: uncharacterized protein YP_004464888.1 InterPro IPR009665; KEGG: amt:Amet_4785 hypothetical protein; PFAM: protein of unknown function DUF1256; SPTR: uncharacterized protein; TIGRFAM: sporulation protein YyaC; PFAM: Protein of unknown function (DUF1256); TIGRFAM: sporulation protein YyaC YP_004464889.1 InterPro IPR003825; KEGG: cth:Cthe_2712 hypothetical protein; PFAM: Colicin V production protein; SPTR: uncharacterized protein; PFAM: Colicin V production protein YP_004464890.1 KEGG: csc:Csac_0432 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464891.1 COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR000005: IPR018062: IPR018060: IPR020449; KEGG: efa:EF0432 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain YP_004464892.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115: IPR004437; KEGG: tmt:Tmath_2277 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004464893.1 COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004464894.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115: IPR004437; KEGG: tte:TTE2790 transcriptional regulator; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins YP_004464895.1 COGs: COG1926 phosphoribosyltransferase; KEGG: tjr:TherJR_2996 phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain YP_004464896.1 InterPro IPR019712; KEGG: mta:Moth_0157 hypothetical protein; PFAM: Protein of unknown function DUF2600; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2600) YP_004464897.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mev:Metev_1593 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004464898.1 KEGG: ate:Athe_0943 hypothetical protein; SPTR: uncharacterized protein YP_004464899.1 KEGG: dpe:Dper_GL19144 GL19144 gene product from transcript GL19144-RA; SPTR: GA18653 YP_004464900.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dhd:Dhaf_3342 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase YP_004464901.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158: IPR007197: IPR006638; KEGG: aoe:Clos_1831 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain YP_004464902.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682; KEGG: aoe:Clos_2870 16S rRNA methyltransferase GidB; PFAM: glucose inhibited division protein; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA methyltransferase GidB YP_004464903.1 COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; InterPro IPR002218: IPR020595: IPR013027: IPR004416; KEGG: cth:Cthe_2364 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: glucose-inhibited division protein A; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; TIGRFAM: glucose inhibited division protein A; manually curated; PFAM: Glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A YP_004464904.1 COGs: COG0486 GTPase; InterPro IPR018948: IPR002917: IPR006073: IPR004520: IPR 005225; KEGG: aoe:Clos_2872 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE-like; GTP-binding protein HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein domain YP_004464905.1 COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: dau:Daud_2234 single-stranded nucleic acid binding R3H domain-containing protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: Single-stranded nucleic acid binding R3H domain protein; PFAM: R3H domain YP_004464906.1 COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: tte:TTE2799 preprotein translocase subunit YidC; PFAM: 60 kDa inner membrane insertion protein; SPTR: YidC translocase/secretase; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain YP_004464907.1 COGs: COG0759 conserved hypothetical protein; InterPro IPR002696; KEGG: cno:NT01CX_0870 hypothetical protein; PFAM: protein of unknown function DUF37; SPTR: UPF0161 protein TtheDRAFT_2097; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD YP_004464908.1 COGs: COG0594 RNase P protein component; InterPro IPR000100; KEGG: cbi:CLJ_B3986 ribonuclease P; PFAM: ribonuclease P protein; SPTR: Ribonuclease P protein component; TIGRFAM: ribonuclease P protein component; PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_004464909.1 InterPro IPR000271; KEGG: ppe:PEPE_1847 50S ribosomal protein L34; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type YP_004464910.1 COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: mae:Maeo_0598 uroporphyrinogen decarboxylase; SPTR: Uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_004464911.1 COGs: COG3345 Alpha-galactosidase; InterPro IPR000111: IPR002252; KEGG: ttr:Tter_2324 glycoside hydrolase clan GH-D; PFAM: glycoside hydrolase clan GH-D; PRIAM: Alpha-galactosidase; SPTR: Glycoside hydrolase clan GH-D; PFAM: Melibiase YP_004464912.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_1298 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004464913.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csc:Csac_2553 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464914.1 COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: csc:Csac_1357 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004464915.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR000005: IPR018062: IPR018060: IPR 020449; KEGG: pjd:Pjdr2_4275 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004464916.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003660: IPR010559: IPR003594; KEGG: pjd:Pjdr2_5331 cache sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase