-- dump date 20111121_013200 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 661410000001 SEQ_END SEQ_END NC_012987.1 141504 141504 DR NC_012987.1; contig end 141504..141504 Methylobacterium extorquens DM4 661410000002 SEQ_END SEQ_END NC_012988.1 5943768 5943768 DR NC_012988.1; contig end 5943768..5943768 Methylobacterium extorquens DM4 661410000003 SEQ_END SEQ_END NC_012989.1 38579 38579 DR NC_012989.1; contig end 38579..38579 Methylobacterium extorquens DM4 YP_003065644.1 CDS p1METDI0001 NC_012987.1 77 247 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 77..247 Methylobacterium extorquens DM4 8190526 YP_003065645.1 CDS p1METDI0002 NC_012987.1 244 1008 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 244..1008 Methylobacterium extorquens DM4 8190390 YP_003065646.1 CDS p1METDI0003 NC_012987.1 1005 2027 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1005..2027 Methylobacterium extorquens DM4 8190391 YP_003065647.1 CDS p1METDI0004 NC_012987.1 2024 3010 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2024..3010 Methylobacterium extorquens DM4 8190392 YP_003065648.1 CDS p1METDI0005 NC_012987.1 3019 5274 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3019..5274 Methylobacterium extorquens DM4 8190393 YP_003065649.1 CDS p1METDI0006 NC_012987.1 5278 6600 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5278..6600 Methylobacterium extorquens DM4 8190394 YP_003065650.1 CDS rpA2 NC_012987.1 7314 8570 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12383728; Product type f : factor; Replication protein A 7314..8570 Methylobacterium extorquens DM4 8190396 YP_003065651.1 CDS repB2 NC_012987.1 8723 9571 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12383728; Product type f : factor; Replication protein B 8723..9571 Methylobacterium extorquens DM4 8190520 YP_003065652.1 CDS repC NC_012987.1 9776 10987 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8763954; Product type pf : putative factor; replication initiation protein RepC 9776..10987 Methylobacterium extorquens DM4 8190515 YP_003065653.1 CDS p1METDI0011 NC_012987.1 11875 12237 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 11875..12237 Methylobacterium extorquens DM4 8190516 YP_003065654.1 CDS p1METDI0013 NC_012987.1 12844 14343 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi7, IS21 family (ORF 1) 12844..14343 Methylobacterium extorquens DM4 8190398 YP_003065655.1 CDS p1METDI0014 NC_012987.1 14340 15182 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi7, IS21 family (ORF 2) 14340..15182 Methylobacterium extorquens DM4 8190399 YP_003065656.1 CDS p1METDI0016 NC_012987.1 16629 18164 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi2, ISL3 family complement(16629..18164) Methylobacterium extorquens DM4 8190401 YP_003065657.1 CDS p1METDI0018 NC_012987.1 18598 19908 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMex3, IS256 family complement(18598..19908) Methylobacterium extorquens DM4 8190403 YP_003065658.1 CDS p1METDI0022 NC_012987.1 22671 23045 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 22671..23045 Methylobacterium extorquens DM4 8190511 YP_003065659.1 CDS actP NC_012987.1 23042 24733 D Evidence 2b : Function of strongly homologous gene; Product type pt : putative transporter; sodium:solute symporter family protein 23042..24733 Methylobacterium extorquens DM4 8190407 YP_003065660.1 CDS p1METDI0024 NC_012987.1 24915 25949 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi11, IS481 family 24915..25949 Methylobacterium extorquens DM4 8190512 YP_003065661.1 CDS p1METDI0025 NC_012987.1 27580 28797 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 27580..28797 Methylobacterium extorquens DM4 8190408 YP_003065662.1 CDS serA NC_012987.1 29293 30546 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7719856; Product type e : enzyme; D-3-phosphoglycerate dehydrogenase 29293..30546 Methylobacterium extorquens DM4 8190409 YP_003065663.1 CDS p1METDI0027 NC_012987.1 30566 31993 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative D-lactate dehydrogenase (cytochrome) 30566..31993 Methylobacterium extorquens DM4 8190521 YP_003065664.1 CDS p1METDI0030 NC_012987.1 33125 34303 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 33125..34303 Methylobacterium extorquens DM4 8190412 YP_003065665.1 CDS p1METDI0031 NC_012987.1 34627 35832 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi25, IS30 family 34627..35832 Methylobacterium extorquens DM4 8190413 YP_003065666.1 CDS rffG NC_012987.1 37078 38136 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7559340; Product type e : enzyme; dTDP-glucose 4,6-dehydratase 37078..38136 Methylobacterium extorquens DM4 8190415 YP_003065667.1 CDS rfbD NC_012987.1 38154 39044 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; dTDP-4-dehydrorhamnose reductase 38154..39044 Methylobacterium extorquens DM4 8190518 YP_003065668.1 CDS rffH NC_012987.1 39060 39950 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7559340; Product type e : enzyme; Glucose-1-phosphate thymidylyltransferase 39060..39950 Methylobacterium extorquens DM4 8190517 YP_003065669.1 CDS p1METDI0036 NC_012987.1 45402 45692 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 45402..45692 Methylobacterium extorquens DM4 8190519 YP_003065670.1 CDS p1METDI0039 NC_012987.1 47301 48806 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 47301..48806 Methylobacterium extorquens DM4 8190418 YP_003065671.1 CDS p1METDI0040 NC_012987.1 48955 50313 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi28, IS701 family 48955..50313 Methylobacterium extorquens DM4 8190419 YP_003065672.1 CDS p1METDI0043 NC_012987.1 50992 51726 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi27, IS21 family (ORF 2) complement(50992..51726) Methylobacterium extorquens DM4 8190421 YP_003065673.1 CDS p1METDI0044 NC_012987.1 51723 53222 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi27, IS21 family (ORF 1) complement(51723..53222) Methylobacterium extorquens DM4 8190422 YP_003065674.1 CDS p1METDI0051 NC_012987.1 60183 60542 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(60183..60542) Methylobacterium extorquens DM4 8190428 YP_003065675.1 CDS p1METDI0052 NC_012987.1 60924 61985 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3486297; Product type pe : putative enzyme; putative Phage integrase (cre-like) complement(60924..61985) Methylobacterium extorquens DM4 8190429 YP_003065676.1 CDS p1METDI0053 NC_012987.1 62430 62855 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 62430..62855 Methylobacterium extorquens DM4 8190430 YP_003065677.1 CDS p1METDI0054 NC_012987.1 63207 64172 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallo-hydrolase/oxidoreductase 63207..64172 Methylobacterium extorquens DM4 8190431 YP_003065678.1 CDS p1METDI0055 NC_012987.1 64186 64653 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(64186..64653) Methylobacterium extorquens DM4 8190432 YP_003065679.1 CDS p1METDI0057 NC_012987.1 65022 65495 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(65022..65495) Methylobacterium extorquens DM4 8190434 YP_003065680.1 CDS p1METDI0059 NC_012987.1 65866 66825 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(65866..66825) Methylobacterium extorquens DM4 8190435 YP_003065681.1 CDS p1METDI0060 NC_012987.1 66945 68405 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8297211; Product type e : enzyme; succinate-semialdehyde dehydrogenase I, NADP-dependent (gabD-like) complement(66945..68405) Methylobacterium extorquens DM4 8190436 YP_003065682.1 CDS p1METDI0061 NC_012987.1 68469 69626 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2935393; Product type pe : putative enzyme; putative Iron-containing alcohol dehydrogenase complement(68469..69626) Methylobacterium extorquens DM4 8190437 YP_003065683.1 CDS p1METDI0062 NC_012987.1 69649 70284 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative high-affinity branched-chain amino acid transporter, ATP-binding component of ABC transporter (livF-like) complement(69649..70284) Methylobacterium extorquens DM4 8190438 YP_003065684.1 CDS p1METDI0063 NC_012987.1 70463 71242 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative high-affinity branched-chain amino acid transporter, ATP-binding component of ABC transporter (livG-like) complement(70463..71242) Methylobacterium extorquens DM4 8190439 YP_003065685.1 CDS p1METDI0064 NC_012987.1 71239 72219 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative high-affinity branched-chain amino acid transporter, membrane component of ABC transporter (livM-like) complement(71239..72219) Methylobacterium extorquens DM4 8190440 YP_003065686.1 CDS p1METDI0065 NC_012987.1 72216 73112 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative high-affinity branched-chain amino acid transporter, membrane component of ABC transporter (livH-like) complement(72216..73112) Methylobacterium extorquens DM4 8190441 YP_003065687.1 CDS p1METDI0066 NC_012987.1 73175 74506 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein complement(73175..74506) Methylobacterium extorquens DM4 8190442 YP_003065688.1 CDS p1METDI0067 NC_012987.1 74651 75385 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Regulatory proteins, AttJ 74651..75385 Methylobacterium extorquens DM4 8190443 YP_003065689.1 CDS dep NC_012987.1 77047 78372 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 11114905, 11208803, 11267773, 12898135; Product type e : enzyme; polyhydroxybutanoate depolymerase complement(77047..78372) Methylobacterium extorquens DM4 8190447 YP_003065690.1 CDS p1METDI0072 NC_012987.1 78696 79139 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12399487; putative granule-associated 20 kDa protein 78696..79139 Methylobacterium extorquens DM4 8190514 YP_003065691.1 CDS p1METDI0074 NC_012987.1 79959 80801 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi16, IS3 family (ORF 2) 79959..80801 Methylobacterium extorquens DM4 8190449 YP_003065692.1 CDS p1METDI0076 NC_012987.1 81578 82408 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi26, IS5 family complement(81578..82408) Methylobacterium extorquens DM4 8190451 YP_003065693.1 CDS p1METDI0077 NC_012987.1 83073 83951 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(83073..83951) Methylobacterium extorquens DM4 8190452 YP_003065694.1 CDS p1METDI0078 NC_012987.1 84123 85061 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 84123..85061 Methylobacterium extorquens DM4 8190453 YP_003065695.1 CDS p1METDI0079 NC_012987.1 85091 86107 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADPH quinone oxidoreductase, Zinc-containing alcohol dehydrogenase superfamily 85091..86107 Methylobacterium extorquens DM4 8190454 YP_003065696.1 CDS p1METDI0085 NC_012987.1 89802 91289 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sensory box/GGDEF family protein, putative protein with GAF:PAS/PAC:GGDEF domains 89802..91289 Methylobacterium extorquens DM4 8190460 YP_003065697.1 CDS p1METDI0087 NC_012987.1 92418 93428 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMex29, IS110 family 92418..93428 Methylobacterium extorquens DM4 8190462 YP_003065698.1 CDS p1METDI0090 NC_012987.1 95261 96001 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 95261..96001 Methylobacterium extorquens DM4 8190465 YP_003065699.1 CDS p1METDI0091 NC_012987.1 96187 96618 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(96187..96618) Methylobacterium extorquens DM4 8190466 YP_003065700.1 CDS p1METDI0092 NC_012987.1 96663 97094 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(96663..97094) Methylobacterium extorquens DM4 8190467 YP_003065701.1 CDS p1METDI0093 NC_012987.1 97171 97479 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(97171..97479) Methylobacterium extorquens DM4 8190468 YP_003065702.1 CDS p1METDI0094 NC_012987.1 97679 98221 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 97679..98221 Methylobacterium extorquens DM4 8190469 YP_003065703.1 CDS p1METDI0095 NC_012987.1 98218 98604 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 98218..98604 Methylobacterium extorquens DM4 8190470 YP_003065704.1 CDS p1METDI0096 NC_012987.1 98675 98932 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative prevent-host-death protein 98675..98932 Methylobacterium extorquens DM4 8190471 YP_003065705.1 CDS p1METDI0097 NC_012987.1 98919 99356 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 98919..99356 Methylobacterium extorquens DM4 8190472 YP_003065706.1 CDS p1METDI0098 NC_012987.1 99599 99769 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 99599..99769 Methylobacterium extorquens DM4 8190473 YP_003065707.1 CDS p1METDI0099 NC_012987.1 99890 100132 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 99890..100132 Methylobacterium extorquens DM4 8190474 YP_003065708.1 CDS p1METDI0100 NC_012987.1 100129 100527 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 100129..100527 Methylobacterium extorquens DM4 8190475 YP_003065709.1 CDS p1METDI0101 NC_012987.1 100742 101191 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 100742..101191 Methylobacterium extorquens DM4 8190476 YP_003065710.1 CDS p1METDI0102 NC_012987.1 101887 102264 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 101887..102264 Methylobacterium extorquens DM4 8190477 YP_003065711.1 CDS p1METDI0103 NC_012987.1 102330 102578 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 102330..102578 Methylobacterium extorquens DM4 8190478 YP_003065712.1 CDS ardC NC_012987.1 102747 103766 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; Antirestriction protein (ardC) 102747..103766 Methylobacterium extorquens DM4 8190479 YP_003065713.1 CDS p1METDI0105 NC_012987.1 103766 104752 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 103766..104752 Methylobacterium extorquens DM4 8190513 YP_003065714.1 CDS p1METDI0107 NC_012987.1 104785 104985 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(104785..104985) Methylobacterium extorquens DM4 8190480 YP_003065715.1 CDS p1METDI0108 NC_012987.1 105344 105607 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 105344..105607 Methylobacterium extorquens DM4 8190481 YP_003065716.1 CDS p1METDI0109 NC_012987.1 105694 106152 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 105694..106152 Methylobacterium extorquens DM4 8190482 YP_003065717.1 CDS p1METDI0110 NC_012987.1 106272 108518 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; ParB-like partition protein, plasmid stabilization protein 106272..108518 Methylobacterium extorquens DM4 8190483 YP_003065718.1 CDS p1METDI0111 NC_012987.1 108806 113161 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methylase/helicase 108806..113161 Methylobacterium extorquens DM4 8190484 YP_003065719.1 CDS p1METDI0112 NC_012987.1 113187 114245 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 113187..114245 Methylobacterium extorquens DM4 8190485 YP_003065720.1 CDS p1METDI0113 NC_012987.1 114494 115522 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 114494..115522 Methylobacterium extorquens DM4 8190486 YP_003065721.1 CDS p1METDI0114 NC_012987.1 115519 115923 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(115519..115923) Methylobacterium extorquens DM4 8190487 YP_003065722.1 CDS p1METDI0115 NC_012987.1 116014 116271 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 116014..116271 Methylobacterium extorquens DM4 8190488 YP_003065723.1 CDS p1METDI0116 NC_012987.1 116373 116576 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(116373..116576) Methylobacterium extorquens DM4 8190489 YP_003065724.1 CDS p1METDI0117 NC_012987.1 116811 116984 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 116811..116984 Methylobacterium extorquens DM4 8190490 YP_003065725.1 CDS traG NC_012987.1 117189 119213 R VirD4 family; conjugal transfer coupling protein TraG complement(117189..119213) Methylobacterium extorquens DM4 8190491 YP_003065726.1 CDS traD NC_012987.1 119210 119404 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; Conjugal transfer protein TraD complement(119210..119404) Methylobacterium extorquens DM4 8190525 YP_003065727.1 CDS traC NC_012987.1 119391 119669 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; conjugal transfer protein TraC complement(119391..119669) Methylobacterium extorquens DM4 8190524 YP_003065728.1 CDS traA NC_012987.1 120036 123749 D Evidence 2b : Function of strongly homologous gene; Product type pf : putative factor; TraA conjugal transfer protein 120036..123749 Methylobacterium extorquens DM4 8190523 YP_003065729.1 CDS p1METDI0122 NC_012987.1 123861 124181 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 123861..124181 Methylobacterium extorquens DM4 8190522 YP_003065730.1 CDS p1METDI0123 NC_012987.1 124178 125479 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 124178..125479 Methylobacterium extorquens DM4 8190492 YP_003065731.1 CDS p1METDI0124 NC_012987.1 125476 126396 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 125476..126396 Methylobacterium extorquens DM4 8190493 YP_003065732.1 CDS p1METDI0125 NC_012987.1 126870 127280 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(126870..127280) Methylobacterium extorquens DM4 8190494 YP_003065733.1 CDS p1METDI0126 NC_012987.1 127283 130270 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(127283..130270) Methylobacterium extorquens DM4 8190495 YP_003065734.1 CDS p1METDI0127 NC_012987.1 130267 130758 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(130267..130758) Methylobacterium extorquens DM4 8190496 YP_003065735.1 CDS p1METDI0128 NC_012987.1 130748 131002 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(130748..131002) Methylobacterium extorquens DM4 8190497 YP_003065736.1 CDS p1METDI0129 NC_012987.1 130999 132282 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(130999..132282) Methylobacterium extorquens DM4 8190498 YP_003065737.1 CDS p1METDI0130 NC_012987.1 132293 133468 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; Putative IcmK-like type IV secretion system protein precursor complement(132293..133468) Methylobacterium extorquens DM4 8190499 YP_003065738.1 CDS p1METDI0131 NC_012987.1 133465 134121 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(133465..134121) Methylobacterium extorquens DM4 8190500 YP_003065739.1 CDS p1METDI0132 NC_012987.1 134118 134393 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(134118..134393) Methylobacterium extorquens DM4 8190501 YP_003065740.1 CDS p1METDI0133 NC_012987.1 134395 134979 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(134395..134979) Methylobacterium extorquens DM4 8190502 YP_003065741.1 CDS p1METDI0134 NC_012987.1 135814 136305 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 135814..136305 Methylobacterium extorquens DM4 8190503 YP_003065742.1 CDS p1METDI0135 NC_012987.1 136322 136852 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(136322..136852) Methylobacterium extorquens DM4 8190504 YP_003065743.1 CDS p1METDI0136 NC_012987.1 137087 138286 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 137087..138286 Methylobacterium extorquens DM4 8190505 YP_003065744.1 CDS p1METDI0137 NC_012987.1 138290 139471 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Type II/IV secretion system protein (ATPase) 138290..139471 Methylobacterium extorquens DM4 8190506 YP_003065745.1 CDS p1METDI0138 NC_012987.1 139440 140090 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 139440..140090 Methylobacterium extorquens DM4 8190507 YP_003065746.1 CDS p1METDI0139 NC_012987.1 140123 140332 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 140123..140332 Methylobacterium extorquens DM4 8190508 YP_003065747.1 CDS p1METDI0140 NC_012987.1 140317 140994 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 140317..140994 Methylobacterium extorquens DM4 8190509 YP_003065748.1 CDS p1METDI0141 NC_012987.1 141009 141389 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 141009..141389 Methylobacterium extorquens DM4 8190510 YP_003065749.1 CDS dnaA NC_012988.1 710 2215 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 710..2215 Methylobacterium extorquens DM4 8196384 YP_003065750.1 CDS dnaN NC_012988.1 2535 3656 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2535..3656 Methylobacterium extorquens DM4 8195301 YP_003065751.1 CDS recF NC_012988.1 3697 4851 D Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; putative RecF protein 3697..4851 Methylobacterium extorquens DM4 8195309 YP_003065752.1 CDS METDI0004 NC_012988.1 4855 5259 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4855..5259) Methylobacterium extorquens DM4 8195969 YP_003065753.1 CDS METDI0005 NC_012988.1 5259 5498 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5259..5498) Methylobacterium extorquens DM4 8190538 YP_003065754.1 CDS recQ NC_012988.1 5601 7448 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3027506; Product type e : enzyme; ATP-dependent DNA helicase 5601..7448 Methylobacterium extorquens DM4 8190539 YP_003065755.1 CDS METDI0007 NC_012988.1 7506 7784 R Evidence 6 : Doubtful CDS; hypothetical protein complement(7506..7784) Methylobacterium extorquens DM4 8195974 YP_003065756.1 CDS METDI0008 NC_012988.1 8160 8846 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 8160..8846 Methylobacterium extorquens DM4 8190540 YP_003065757.1 CDS recD NC_012988.1 8968 11169 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Helicase 8968..11169 Methylobacterium extorquens DM4 8190541 YP_003065758.1 CDS METDI0010 NC_012988.1 11313 12497 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 11313..12497 Methylobacterium extorquens DM4 8195968 YP_003065759.1 CDS purL NC_012988.1 12688 14913 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1398079, 8828210; Product type e : enzyme; phosphoribosylformylglycinamide synthetase 12688..14913 Methylobacterium extorquens DM4 8190542 YP_003065760.1 CDS METDI0012 NC_012988.1 14941 15177 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; BolA-like protein 14941..15177 Methylobacterium extorquens DM4 8195937 YP_003065761.1 CDS METDI0013 NC_012988.1 15251 15586 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; glutaredoxin-like protein 15251..15586 Methylobacterium extorquens DM4 8190543 YP_003065762.1 CDS METDI0014 NC_012988.1 15659 16561 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase 15659..16561 Methylobacterium extorquens DM4 8190544 YP_003065763.1 CDS METDI0015 NC_012988.1 16670 17554 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 16670..17554 Methylobacterium extorquens DM4 8190545 YP_003065764.1 CDS METDI0017 NC_012988.1 17983 18816 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(17983..18816) Methylobacterium extorquens DM4 8190546 YP_003065765.1 CDS METDI0018 NC_012988.1 19186 21231 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor hybrid histidine kinase with PAS/PAC motif and response regulator receiver domains complement(19186..21231) Methylobacterium extorquens DM4 8190547 YP_003065766.1 CDS METDI0019 NC_012988.1 21231 22757 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(21231..22757) Methylobacterium extorquens DM4 8190548 YP_003065767.1 CDS METDI0020 NC_012988.1 23143 24348 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 23143..24348 Methylobacterium extorquens DM4 8190549 YP_003065768.1 CDS METDI0021 NC_012988.1 24379 25377 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Short-chain dehydrogenase/reductase SDR complement(24379..25377) Methylobacterium extorquens DM4 8190550 YP_003065769.1 CDS METDI0022 NC_012988.1 25500 26186 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, GntR family complement(25500..26186) Methylobacterium extorquens DM4 8190551 YP_003065770.1 CDS mdcA NC_012988.1 26832 28478 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; malonate decarboxylase, alpha subunit 26832..28478 Methylobacterium extorquens DM4 8190553 YP_003065771.1 CDS mdcC NC_012988.1 28486 28794 D acyl carrier protein of malonate decarboxylase; malonate decarboxylase subunit delta 28486..28794 Methylobacterium extorquens DM4 8195670 YP_003065772.1 CDS mdcD NC_012988.1 28797 29729 D The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A; malonate decarboxylase subunit beta 28797..29729 Methylobacterium extorquens DM4 8195672 YP_003065773.1 CDS mdcE NC_012988.1 29716 30432 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Malonate decarboxylase, gamma subunit 29716..30432 Methylobacterium extorquens DM4 8195673 YP_003065774.1 CDS METDI0028 NC_012988.1 30425 31084 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; phosphoribosyl-dephospho-CoA transferase 30425..31084 Methylobacterium extorquens DM4 8195674 YP_003065775.1 CDS mdcB NC_012988.1 31081 31938 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2'-(5''-triphosphoribosyl)-3'-dephosphocoenzyme- A synthase 31081..31938 Methylobacterium extorquens DM4 8190554 YP_003065776.1 CDS METDI0030 NC_012988.1 31935 32858 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9642179; Product type e : enzyme; Acyl transferase domain protein, putative malonyl CoA-acyl carrier protein transacylase (MCT, fabD-like) 31935..32858 Methylobacterium extorquens DM4 8195671 YP_003065777.1 CDS METDI0031 NC_012988.1 32996 35380 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; putative General secretion pathway protein D complement(32996..35380) Methylobacterium extorquens DM4 8190555 YP_003065778.1 CDS METDI0032 NC_012988.1 35472 36341 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative general secretory pathway protein complement(35472..36341) Methylobacterium extorquens DM4 8190556 YP_003065779.1 CDS METDI0033 NC_012988.1 36356 36967 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1944223, 2129543; Product type m : membrane component; putative general secretion pathway protein complement(36356..36967) Methylobacterium extorquens DM4 8190557 YP_003065780.1 CDS METDI0034 NC_012988.1 36960 37355 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative general secretion pathway protein complement(36960..37355) Methylobacterium extorquens DM4 8190558 YP_003065781.1 CDS METDI0035 NC_012988.1 37352 37825 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative general secretion pathway protein complement(37352..37825) Methylobacterium extorquens DM4 8190559 YP_003065782.1 CDS METDI0036 NC_012988.1 37946 38257 D Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein 37946..38257 Methylobacterium extorquens DM4 8190560 YP_003065783.1 CDS METDI0037 NC_012988.1 38421 38633 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 38421..38633 Methylobacterium extorquens DM4 8190561 YP_003065784.1 CDS METDI0038 NC_012988.1 38830 39207 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(38830..39207) Methylobacterium extorquens DM4 8190562 YP_003065785.1 CDS METDI0039 NC_012988.1 40276 40584 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 40276..40584 Methylobacterium extorquens DM4 8190563 YP_003065786.1 CDS METDI0040 NC_012988.1 40718 41089 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 40718..41089 Methylobacterium extorquens DM4 8190564 YP_003065787.1 CDS METDI0041 NC_012988.1 42149 42574 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) 42149..42574 Methylobacterium extorquens DM4 8190565 YP_003065788.1 CDS METDI0042 NC_012988.1 42349 42903 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) 42349..42903 Methylobacterium extorquens DM4 8190566 YP_003065789.1 CDS METDI0043 NC_012988.1 43148 43609 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 43148..43609 Methylobacterium extorquens DM4 8190567 YP_003065790.1 CDS METDI0045 NC_012988.1 43940 44143 D Evidence 6 : Doubtful CDS; hypothetical protein 43940..44143 Methylobacterium extorquens DM4 8190568 YP_003065791.1 CDS METDI0046 NC_012988.1 45341 45859 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative integrase/resolvase recombinase 45341..45859 Methylobacterium extorquens DM4 8190569 YP_003065792.1 CDS METDI0047 NC_012988.1 46637 46999 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(46637..46999) Methylobacterium extorquens DM4 8190570 YP_003065793.1 CDS METDI0048 NC_012988.1 48233 48526 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(48233..48526) Methylobacterium extorquens DM4 8190571 YP_003065794.1 CDS METDI0049 NC_012988.1 48529 49293 R Evidence 2b : Function of strongly homologous gene; Product type pr : putative regulator; Regulatory protein, Crp (cAMP Receptor Protein) complement(48529..49293) Methylobacterium extorquens DM4 8190572 YP_003065795.1 CDS METDI0050 NC_012988.1 49566 50198 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family, with N-terminal cNMP-binding domain 49566..50198 Methylobacterium extorquens DM4 8190573 YP_003065796.1 CDS METDI0051 NC_012988.1 50602 50811 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(50602..50811) Methylobacterium extorquens DM4 8190574 YP_003065797.1 CDS METDI0052 NC_012988.1 50850 51383 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(50850..51383) Methylobacterium extorquens DM4 8190575 YP_003065798.1 CDS METDI0053 NC_012988.1 51430 52740 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative site-specific recombinase complement(51430..52740) Methylobacterium extorquens DM4 8190576 YP_003065799.1 CDS trpB NC_012988.1 53123 54364 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(53123..54364) Methylobacterium extorquens DM4 8196250 YP_003065800.1 CDS trpF NC_012988.1 54487 55134 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10360571, 9166771; Product type pe : putative enzyme; putative phosphoribosylanthranilate isomerase complement(54487..55134) Methylobacterium extorquens DM4 8196273 YP_003065801.1 CDS METDI0056 NC_012988.1 55158 55526 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(55158..55526) Methylobacterium extorquens DM4 8196277 YP_003065802.1 CDS ihfB NC_012988.1 55752 56060 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8407826, 92021785, 92155171, 93078609; Product type h : extrachromosomal origin; integration host factor (IHF), beta subunit, site-specific recombination complement(55752..56060) Methylobacterium extorquens DM4 8190578 YP_003065803.1 CDS sppA NC_012988.1 56102 57067 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; putative peptidase complement(56102..57067) Methylobacterium extorquens DM4 8195590 YP_003065804.1 CDS METDI0059 NC_012988.1 57328 58653 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; hypothetical protein complement(57328..58653) Methylobacterium extorquens DM4 8196144 YP_003065805.1 CDS rpsA NC_012988.1 58746 60458 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(58746..60458) Methylobacterium extorquens DM4 8190579 YP_003065806.1 CDS rrm1 NC_012988.1 60873 61679 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; rRNA methylase complement(60873..61679) Methylobacterium extorquens DM4 8196052 YP_003065807.1 CDS METDI0063 NC_012988.1 62331 62798 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(62331..62798) Methylobacterium extorquens DM4 8196223 YP_003065808.1 CDS METDI0066 NC_012988.1 63245 64183 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; Pirin-like protein 63245..64183 Methylobacterium extorquens DM4 8190580 YP_003065809.1 CDS kefB NC_012988.1 64286 66052 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; potassium:proton antiporter (CPA2 family) 64286..66052 Methylobacterium extorquens DM4 8190581 YP_003065810.1 CDS METDI0068 NC_012988.1 66232 66951 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; putative cytochrome biogenesis protein 66232..66951 Methylobacterium extorquens DM4 8195622 YP_003065811.1 CDS METDI0069 NC_012988.1 67059 67673 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative 3-methyladenine DNA glycosylase 67059..67673 Methylobacterium extorquens DM4 8190582 YP_003065812.1 CDS METDI0070 NC_012988.1 67679 67936 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(67679..67936) Methylobacterium extorquens DM4 8190583 YP_003065813.1 CDS METDI0071 NC_012988.1 68264 68482 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 68264..68482 Methylobacterium extorquens DM4 8190584 YP_003065814.1 CDS METDI0072 NC_012988.1 68597 70294 R Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; Methyl-accepting chemotaxis receptor/sensory transducer complement(68597..70294) Methylobacterium extorquens DM4 8190585 YP_003065815.1 CDS METDI0073 NC_012988.1 70677 72299 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-binding protein with two ATPase domains, ABC transporter related 70677..72299 Methylobacterium extorquens DM4 8190586 YP_003065816.1 CDS METDI0074 NC_012988.1 72307 72663 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(72307..72663) Methylobacterium extorquens DM4 8190587 YP_003065817.1 CDS METDI0075 NC_012988.1 72673 72912 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(72673..72912) Methylobacterium extorquens DM4 8190588 YP_003065818.1 CDS METDI0076 NC_012988.1 73127 73771 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(73127..73771) Methylobacterium extorquens DM4 8190589 YP_003065819.1 CDS METDI0077 NC_012988.1 73782 74417 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8121412; hypothetical protein complement(73782..74417) Methylobacterium extorquens DM4 8190590 YP_003065820.1 CDS METDI0078 NC_012988.1 74524 75507 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 74524..75507 Methylobacterium extorquens DM4 8190591 YP_003065821.1 CDS METDI0079 NC_012988.1 75528 76712 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8631780; Product type pe : putative enzyme; putative glycosyl transferase complement(75528..76712) Methylobacterium extorquens DM4 8190592 YP_003065822.1 CDS METDI0080 NC_012988.1 76712 77752 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11583114; Product type pe : putative enzyme; putative glycosyl transferase complement(76712..77752) Methylobacterium extorquens DM4 8190593 YP_003065823.1 CDS METDI0081 NC_012988.1 77810 79864 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 77810..79864 Methylobacterium extorquens DM4 8190594 YP_003065824.1 CDS METDI0082 NC_012988.1 79886 80776 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15294902; Product type pe : putative enzyme; putative glycosyl transferase 79886..80776 Methylobacterium extorquens DM4 8190595 YP_003065825.1 CDS METDI0083 NC_012988.1 80825 81973 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase; putative UDP-N-acetylglucosamine, LPS N-acetylglucosamine transferase 80825..81973 Methylobacterium extorquens DM4 8190596 YP_003065826.1 CDS METDI0084 NC_012988.1 82024 82965 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 82024..82965 Methylobacterium extorquens DM4 8190597 YP_003065827.1 CDS METDI0085 NC_012988.1 82962 84017 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12068013; Product type pe : putative enzyme; putative glycosyl transferase 82962..84017 Methylobacterium extorquens DM4 8190598 YP_003065828.1 CDS METDI0086 NC_012988.1 84063 84731 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14523113, 9791104; Product type pe : putative enzyme; putative methyltransferase, putative O-methyltransferase 84063..84731 Methylobacterium extorquens DM4 8190599 YP_003065829.1 CDS METDI0087 NC_012988.1 85417 86526 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal dependent phosphohydrolase with a response regulator receiver domain; HD-GYP domain protein 85417..86526 Methylobacterium extorquens DM4 8190600 YP_003065830.1 CDS METDI0088 NC_012988.1 86691 89387 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Excinuclease ABC, A subunit 86691..89387 Methylobacterium extorquens DM4 8190601 YP_003065831.1 CDS METDI0089 NC_012988.1 89429 90385 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11481431; Product type pe : putative enzyme; putative transcriptional regulator, AraC family complement(89429..90385) Methylobacterium extorquens DM4 8190602 YP_003065832.1 CDS METDI0090 NC_012988.1 90513 91301 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR 90513..91301 Methylobacterium extorquens DM4 8190603 YP_003065833.1 CDS iorA NC_012988.1 91494 91940 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7782304, 8157655; Product type e : enzyme; isoquinoline 1-oxidoreductase, alpha subunit 91494..91940 Methylobacterium extorquens DM4 8190604 YP_003065834.1 CDS iorB NC_012988.1 91951 94209 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; isoquinoline 1-oxidoreductase, beta subunit 91951..94209 Methylobacterium extorquens DM4 8195603 YP_003065835.1 CDS METDI0093 NC_012988.1 94220 95227 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative potassium-tellurite ethidium and proflavin transporter 94220..95227 Methylobacterium extorquens DM4 8195604 YP_003065836.1 CDS serA NC_012988.1 95459 96709 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7719856; Product type e : enzyme; D-3-phosphoglycerate dehydrogenase 95459..96709 Methylobacterium extorquens DM4 8190605 YP_003065837.1 CDS METDI0095 NC_012988.1 96725 98122 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative D-lactate dehydrogenase (cytochrome) 96725..98122 Methylobacterium extorquens DM4 8196109 YP_003065838.1 CDS METDI0096 NC_012988.1 98856 99515 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative nitrite reductase, formate-dependent, penta-heme cytochrome c 98856..99515 Methylobacterium extorquens DM4 8190606 YP_003065839.1 CDS METDI0097 NC_012988.1 99503 102313 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S ferredoxin, iron-sulfur binding 99503..102313 Methylobacterium extorquens DM4 8190607 YP_003065840.1 CDS METDI0098 NC_012988.1 102310 103680 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Polysulphide reductase, NrfD 102310..103680 Methylobacterium extorquens DM4 8190608 YP_003065841.1 CDS METDI0099 NC_012988.1 103677 104195 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 103677..104195 Methylobacterium extorquens DM4 8190609 YP_003065842.1 CDS METDI0100 NC_012988.1 104192 104719 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome c family protein 104192..104719 Methylobacterium extorquens DM4 8190610 YP_003065843.1 CDS METDI0101 NC_012988.1 104716 105672 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 104716..105672 Methylobacterium extorquens DM4 8190611 YP_003065844.1 CDS METDI0102 NC_012988.1 105647 106186 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 105647..106186 Methylobacterium extorquens DM4 8190612 YP_003065845.1 CDS METDI0103 NC_012988.1 106186 107274 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Cytochrome c oxidase, subunit II (coxB-like) 106186..107274 Methylobacterium extorquens DM4 8190613 YP_003065846.1 CDS coxA NC_012988.1 107306 108997 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; cytochrome c oxidase subunit I 107306..108997 Methylobacterium extorquens DM4 8190614 YP_003065847.1 CDS METDI0105 NC_012988.1 108994 109683 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Cytochrome c oxidase, subunit III 108994..109683 Methylobacterium extorquens DM4 8195204 YP_003065848.1 CDS METDI0106 NC_012988.1 109680 109982 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cytochrome oxidase subunit IV 109680..109982 Methylobacterium extorquens DM4 8190615 YP_003065849.1 CDS METDI0108 NC_012988.1 110498 110782 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(110498..110782) Methylobacterium extorquens DM4 8190617 YP_003065850.1 CDS METDI0109 NC_012988.1 111049 111579 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor 111049..111579 Methylobacterium extorquens DM4 8190618 YP_003065851.1 CDS METDI0110 NC_012988.1 111582 112349 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 111582..112349 Methylobacterium extorquens DM4 8190619 YP_003065852.1 CDS METDI0111 NC_012988.1 112357 113469 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative catalase 112357..113469 Methylobacterium extorquens DM4 8190620 YP_003065853.1 CDS METDI0112 NC_012988.1 113466 114032 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; Cytochrome B561 113466..114032 Methylobacterium extorquens DM4 8190621 YP_003065854.1 CDS METDI0113 NC_012988.1 113991 114251 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(113991..114251) Methylobacterium extorquens DM4 8190622 YP_003065855.1 CDS METDI0115 NC_012988.1 114518 114607 D one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit F 114518..114607 Methylobacterium extorquens DM4 8190623 YP_003065856.1 CDS kdpA NC_012988.1 114629 116344 D catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 114629..116344 Methylobacterium extorquens DM4 8190624 YP_003065857.1 CDS METDI0117 NC_012988.1 116373 116534 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 116373..116534 Methylobacterium extorquens DM4 8195614 YP_003065858.1 CDS kdpB NC_012988.1 116594 118684 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6146979, 92202140, 93167625, 9858692; Product type t : transporter; Potassium-transporting ATPase B chain (Potassium-translocating ATPase B chain) (ATP phosphohydrolase [potassium-transporting] B chain) (Potassium binding and translocating subunit B) 116594..118684 Methylobacterium extorquens DM4 8190625 YP_003065859.1 CDS kdpC NC_012988.1 118708 119313 D one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 118708..119313 Methylobacterium extorquens DM4 8195615 YP_003065860.1 CDS kdpD NC_012988.1 119324 122041 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sensory histidine kinase 119324..122041 Methylobacterium extorquens DM4 8195616 YP_003065861.1 CDS kdpE NC_012988.1 122038 122784 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; response regulator in two-component regulatory system with KdpD, regulation of potassium translocation (OmpR family) 122038..122784 Methylobacterium extorquens DM4 8195617 YP_003065862.1 CDS METDI0122 NC_012988.1 123034 123267 R Evidence 6 : Doubtful CDS; hypothetical protein complement(123034..123267) Methylobacterium extorquens DM4 8195618 YP_003065863.1 CDS METDI0123 NC_012988.1 123528 124838 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 123528..124838 Methylobacterium extorquens DM4 8190626 YP_003065864.1 CDS METDI0125 NC_012988.1 125145 126083 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(125145..126083) Methylobacterium extorquens DM4 8190628 YP_003065865.1 CDS METDI0126 NC_012988.1 126080 126868 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(126080..126868) Methylobacterium extorquens DM4 8190629 YP_003065866.1 CDS METDI0127 NC_012988.1 126865 127650 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(126865..127650) Methylobacterium extorquens DM4 8190630 YP_003065867.1 CDS METDI0128 NC_012988.1 127647 128744 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Myo-inositol-1-phosphate synthase complement(127647..128744) Methylobacterium extorquens DM4 8190631 YP_003065868.1 CDS METDI0129 NC_012988.1 128744 129784 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dTDP-glucose 4,6-dehydratase complement(128744..129784) Methylobacterium extorquens DM4 8190632 YP_003065869.1 CDS METDI0130 NC_012988.1 129796 130911 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(129796..130911) Methylobacterium extorquens DM4 8190633 YP_003065870.1 CDS METDI0131 NC_012988.1 130908 132014 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(130908..132014) Methylobacterium extorquens DM4 8190634 YP_003065871.1 CDS METDI0132 NC_012988.1 132011 133138 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(132011..133138) Methylobacterium extorquens DM4 8190635 YP_003065872.1 CDS METDI0133 NC_012988.1 133135 134241 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12068013; Product type pe : putative enzyme; putative glycosyl transferase complement(133135..134241) Methylobacterium extorquens DM4 8190636 YP_003065873.1 CDS METDI0134 NC_012988.1 134232 135527 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Radical SAM domain protein complement(134232..135527) Methylobacterium extorquens DM4 8190637 YP_003065874.1 CDS METDI0135 NC_012988.1 135524 136615 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dTDP-glucose 4,6-dehydratase complement(135524..136615) Methylobacterium extorquens DM4 8190638 YP_003065875.1 CDS METDI0136 NC_012988.1 136612 137724 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative UDP-glucose 4-epimerase complement(136612..137724) Methylobacterium extorquens DM4 8190639 YP_003065876.1 CDS METDI0137 NC_012988.1 137916 138104 D Evidence 6 : Doubtful CDS; hypothetical protein 137916..138104 Methylobacterium extorquens DM4 8190640 YP_003065877.1 CDS METDI0138 NC_012988.1 138526 138993 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(138526..138993) Methylobacterium extorquens DM4 8190641 YP_003065878.1 CDS METDI0139 NC_012988.1 139254 139535 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) 139254..139535 Methylobacterium extorquens DM4 8190642 YP_003065879.1 CDS METDI0140 NC_012988.1 139643 140395 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) 139643..140395 Methylobacterium extorquens DM4 8190643 YP_003065880.1 CDS METDI0141 NC_012988.1 140581 141510 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex17, IS110 family 140581..141510 Methylobacterium extorquens DM4 8190644 YP_003065881.1 CDS umuD NC_012988.1 141912 142367 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; component of DNA polymerase V, subunit D 141912..142367 Methylobacterium extorquens DM4 8190645 YP_003065882.1 CDS umuC NC_012988.1 142364 143515 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; component of DNA polymerase V, subunit C 142364..143515 Methylobacterium extorquens DM4 8196301 YP_003065883.1 CDS METDI0147 NC_012988.1 145410 145631 R Evidence 6 : Doubtful CDS; hypothetical protein complement(145410..145631) Methylobacterium extorquens DM4 8196299 YP_003065884.1 CDS rarA NC_012988.1 146255 147568 D Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; recombination factor protein RarA 146255..147568 Methylobacterium extorquens DM4 8196263 YP_003065885.1 CDS METDI0149 NC_012988.1 147565 149097 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Zn dependent carboxypeptidase 147565..149097 Methylobacterium extorquens DM4 8195964 YP_003065886.1 CDS METDI0150 NC_012988.1 149260 150507 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; molecular chaperone, HSP70 class 149260..150507 Methylobacterium extorquens DM4 8190647 YP_003065887.1 CDS rluC NC_012988.1 150735 152141 D Evidence 2b : Function of strongly homologous gene; PubMedId : 14704707; Product type e : enzyme; pseudouridylate synthase 150735..152141 Methylobacterium extorquens DM4 8190648 YP_003065888.1 CDS METDI0153 NC_012988.1 152750 153475 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase family hydrolase 152750..153475 Methylobacterium extorquens DM4 8195999 YP_003065889.1 CDS METDI0154 NC_012988.1 153536 154339 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 153536..154339 Methylobacterium extorquens DM4 8190649 YP_003065890.1 CDS pccB NC_012988.1 154934 156466 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; propionyl-CoA carboxylase beta chain 154934..156466 Methylobacterium extorquens DM4 8190650 YP_003065891.1 CDS METDI0156 NC_012988.1 156528 157082 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(156528..157082) Methylobacterium extorquens DM4 8195833 YP_003065892.1 CDS METDI0157 NC_012988.1 157519 158166 D Evidence 2b : Function of strongly homologous gene; Product type pr : putative regulator; transcriptional regulator TetR family 157519..158166 Methylobacterium extorquens DM4 8196268 YP_003065893.1 CDS ilvC NC_012988.1 158200 159219 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 158200..159219 Methylobacterium extorquens DM4 8190652 YP_003065894.1 CDS METDI0159 NC_012988.1 159387 160040 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; Pyridoxamine 5'-phosphate oxidase-related 159387..160040 Methylobacterium extorquens DM4 8195593 YP_003065895.1 CDS METDI0160 NC_012988.1 160104 160976 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 160104..160976 Methylobacterium extorquens DM4 8190653 YP_003065896.1 CDS ccr NC_012988.1 161049 162347 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12730156, 15687219, 16926146, 17548827, 8704985; Product type e : enzyme; crotonyl-CoA carboxylase/reductase complement(161049..162347) Methylobacterium extorquens DM4 8190654 YP_003065897.1 CDS katA NC_012988.1 162528 163997 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14702393, 8955300; Product type e : enzyme; catalase (hydroperoxidase II) complement(162528..163997) Methylobacterium extorquens DM4 8195157 YP_003065898.1 CDS ecm NC_012988.1 164364 166430 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11872727, 17548827, 18819910; Product type e : enzyme; ethylmalonyl-CoA mutase 164364..166430 Methylobacterium extorquens DM4 8195612 YP_003065899.1 CDS METDI0164 NC_012988.1 166540 167226 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(166540..167226) Methylobacterium extorquens DM4 8195324 YP_003065900.1 CDS METDI0165 NC_012988.1 167498 168244 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(167498..168244) Methylobacterium extorquens DM4 8190655 YP_003065901.1 CDS METDI0166 NC_012988.1 168353 168682 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, arsR family 168353..168682 Methylobacterium extorquens DM4 8190656 YP_003065902.1 CDS trpS NC_012988.1 168834 169895 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 168834..169895 Methylobacterium extorquens DM4 8190657 YP_003065903.1 CDS METDI0168 NC_012988.1 170011 170184 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(170011..170184) Methylobacterium extorquens DM4 8196279 YP_003065904.1 CDS leuD NC_012988.1 170344 170949 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 170344..170949 Methylobacterium extorquens DM4 8190658 YP_003065905.1 CDS METDI0170 NC_012988.1 170957 171598 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative pyrrolidone-carboxylate peptidase complement(170957..171598) Methylobacterium extorquens DM4 8195631 YP_003065906.1 CDS meaB NC_012988.1 171595 172584 R functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase complement(171595..172584) Methylobacterium extorquens DM4 8190659 YP_003065907.1 CDS METDI0172 NC_012988.1 172731 173765 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 172731..173765 Methylobacterium extorquens DM4 8195677 YP_003065908.1 CDS METDI0174 NC_012988.1 173951 174298 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 173951..174298 Methylobacterium extorquens DM4 8190660 YP_003065909.1 CDS METDI0175 NC_012988.1 174376 176256 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative Acylaminoacyl-peptidase complement(174376..176256) Methylobacterium extorquens DM4 8190661 YP_003065910.1 CDS METDI0176 NC_012988.1 176325 177203 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(176325..177203) Methylobacterium extorquens DM4 8190662 YP_003065911.1 CDS METDI0177 NC_012988.1 177583 177828 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 177583..177828 Methylobacterium extorquens DM4 8190663 YP_003065912.1 CDS sbcD NC_012988.1 177960 179207 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ATP-dependent dsDNA exonuclease 177960..179207 Methylobacterium extorquens DM4 8190664 YP_003065913.1 CDS sbcC NC_012988.1 179219 182965 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Nuclease sbcCD subunit C 179219..182965 Methylobacterium extorquens DM4 8196099 YP_003065914.1 CDS narK NC_012988.1 183228 184487 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative nitrate transporter narK 183228..184487 Methylobacterium extorquens DM4 8196098 YP_003065915.1 CDS METDI0181 NC_012988.1 184570 185337 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative phosphoribosyltransferase complement(184570..185337) Methylobacterium extorquens DM4 8195771 YP_003065916.1 CDS METDI0182 NC_012988.1 185367 185594 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(185367..185594) Methylobacterium extorquens DM4 8190665 YP_003065917.1 CDS METDI0183 NC_012988.1 185798 186691 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 185798..186691 Methylobacterium extorquens DM4 8190666 YP_003065918.1 CDS METDI0184 NC_012988.1 186688 187044 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 186688..187044 Methylobacterium extorquens DM4 8190667 YP_003065919.1 CDS METDI0185 NC_012988.1 187053 188594 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(187053..188594) Methylobacterium extorquens DM4 8190668 YP_003065920.1 CDS METDI0186 NC_012988.1 188626 189042 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative mutator MutT protein precursor; putative NTP pyrophosphohydrolase complement(188626..189042) Methylobacterium extorquens DM4 8190669 YP_003065921.1 CDS METDI0187 NC_012988.1 189039 189761 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(189039..189761) Methylobacterium extorquens DM4 8190670 YP_003065922.1 CDS argJ NC_012988.1 189758 191002 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glutamate N-acetyltransferase/amino-acid acetyltransferase complement(189758..191002) Methylobacterium extorquens DM4 8190671 YP_003065923.1 CDS METDI0189 NC_012988.1 191384 191854 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 191384..191854 Methylobacterium extorquens DM4 8195090 YP_003065924.1 CDS METDI0190 NC_012988.1 191947 192501 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione peroxidase 191947..192501 Methylobacterium extorquens DM4 8190672 YP_003065925.1 CDS METDI0191 NC_012988.1 192518 192784 R Evidence 6 : Doubtful CDS; hypothetical protein complement(192518..192784) Methylobacterium extorquens DM4 8190673 YP_003065926.1 CDS METDI0192 NC_012988.1 192844 193071 D Evidence 6 : Doubtful CDS; hypothetical protein 192844..193071 Methylobacterium extorquens DM4 8190674 YP_003065927.1 CDS METDI0193 NC_012988.1 193262 193504 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 193262..193504 Methylobacterium extorquens DM4 8190675 YP_003065928.1 CDS putA NC_012988.1 193511 196603 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(193511..196603) Methylobacterium extorquens DM4 8190676 YP_003065929.1 CDS METDI0195 NC_012988.1 196706 200233 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(196706..200233) Methylobacterium extorquens DM4 8195941 YP_003065930.1 CDS METDI0196 NC_012988.1 200394 200645 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(200394..200645) Methylobacterium extorquens DM4 8190677 YP_003065931.1 CDS uvrD NC_012988.1 200761 203148 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2254268, 2943729, 6324092, 6379604, 8419285, 91193215, 93328668, 93341925; Product type e : enzyme; DNA-dependent ATPase I and helicase II 200761..203148 Methylobacterium extorquens DM4 8190678 YP_003065932.1 CDS METDI0198 NC_012988.1 203278 203517 R Evidence 6 : Doubtful CDS; hypothetical protein complement(203278..203517) Methylobacterium extorquens DM4 8196332 YP_003065933.1 CDS METDI0199 NC_012988.1 203545 204261 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2160940; Product type pe : putative enzyme; putative phosphate starvation induced PhoH-like protein 203545..204261 Methylobacterium extorquens DM4 8190679 YP_003065934.1 CDS aqpZ NC_012988.1 204331 205071 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 96094287, 99328963, 99448397; Product type t : transporter; water channel (aquaporin Z) (MIP family) complement(204331..205071) Methylobacterium extorquens DM4 8190680 YP_003065935.1 CDS METDI0201 NC_012988.1 205453 206346 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(205453..206346) Methylobacterium extorquens DM4 8195079 YP_003065936.1 CDS glnE NC_012988.1 206397 209360 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11214968; Product type e : enzyme; Glutamate-ammonia-ligase adenylyltransferase ([Glutamate--ammonia-ligase] adenylyltransferase) (Glutamine-synthetase adenylyltransferase) (ATase) complement(206397..209360) Methylobacterium extorquens DM4 8190681 YP_003065937.1 CDS METDI0203 NC_012988.1 209602 210297 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(209602..210297) Methylobacterium extorquens DM4 8195500 YP_003065938.1 CDS METDI0204 NC_012988.1 210633 210929 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 210633..210929 Methylobacterium extorquens DM4 8190682 YP_003065939.1 CDS METDI0205 NC_012988.1 210937 212367 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative sensor histidine kinase; putative membrane protein complement(210937..212367) Methylobacterium extorquens DM4 8190683 YP_003065940.1 CDS cusR NC_012988.1 212364 213062 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11283292, 11399769, 20461235; Product type r : regulator; response regulator in two-component regulatory system with CusS, regulation of copper resistance complement(212364..213062) Methylobacterium extorquens DM4 8190684 YP_003065941.1 CDS METDI0207 NC_012988.1 213089 213598 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(213089..213598) Methylobacterium extorquens DM4 8195231 YP_003065942.1 CDS ssuB NC_012988.1 213675 214454 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20245523, 3549459, 7984428, 99410391, 99436146; Product type t : transporter; alkanesulfonate transport protein (ABC superfamily, atp_bind) complement(213675..214454) Methylobacterium extorquens DM4 8190685 YP_003065943.1 CDS ssuC NC_012988.1 214462 215301 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; alkanesulfonate transporter subunit ; membrane component of ABC superfamily complement(214462..215301) Methylobacterium extorquens DM4 8196154 YP_003065944.1 CDS METDI0210 NC_012988.1 215362 215994 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; transporter protein complement(215362..215994) Methylobacterium extorquens DM4 8196158 YP_003065945.1 CDS METDI0211 NC_012988.1 216003 216977 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; sulfonate transport system substrate-binding protein complement(216003..216977) Methylobacterium extorquens DM4 8190686 YP_003065946.1 CDS glnD NC_012988.1 217137 219923 D catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 217137..219923 Methylobacterium extorquens DM4 8190687 YP_003065947.1 CDS METDI0213 NC_012988.1 220015 220623 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative heat shock protein (HSP-70 COFACTOR), grpE 220015..220623 Methylobacterium extorquens DM4 8195499 YP_003065948.1 CDS METDI0214 NC_012988.1 220732 221067 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(220732..221067) Methylobacterium extorquens DM4 8190688 YP_003065949.1 CDS METDI0215 NC_012988.1 221039 221314 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(221039..221314) Methylobacterium extorquens DM4 8190689 YP_003065950.1 CDS METDI0216 NC_012988.1 221406 222263 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Prephenate dehydratase complement(221406..222263) Methylobacterium extorquens DM4 8190690 YP_003065951.1 CDS kdsB NC_012988.1 222280 223023 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3023327; Product type e : enzyme; 3-deoxy-manno-octulosonate cytidylyltransferase complement(222280..223023) Methylobacterium extorquens DM4 8190691 YP_003065952.1 CDS METDI0218 NC_012988.1 223331 224248 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type c : carrier; putative cytochrome c, class I 223331..224248 Methylobacterium extorquens DM4 8195620 YP_003065953.1 CDS METDI0219 NC_012988.1 224421 226334 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein precursor 224421..226334 Methylobacterium extorquens DM4 8190692 YP_003065954.1 CDS METDI0220 NC_012988.1 226331 228193 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein precursor 226331..228193 Methylobacterium extorquens DM4 8190693 YP_003065955.1 CDS METDI0221 NC_012988.1 228203 229300 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, permease 228203..229300 Methylobacterium extorquens DM4 8190694 YP_003065956.1 CDS METDI0222 NC_012988.1 229369 229872 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase with acyl-CoA N-acyltransferase domain 229369..229872 Methylobacterium extorquens DM4 8190695 YP_003065957.1 CDS METDI0223 NC_012988.1 229986 231518 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Long-chain acyl-CoA synthetase 229986..231518 Methylobacterium extorquens DM4 8190696 YP_003065958.1 CDS METDI0224 NC_012988.1 231579 232361 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8824620; Product type pe : putative enzyme; putative lipopolysaccharide core biosynthesis glycosyl transferase (LpsC-like, kdtX-like) 231579..232361 Methylobacterium extorquens DM4 8190697 YP_003065959.1 CDS METDI0225 NC_012988.1 232539 233249 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative DNA-binding protein; putative AP2/ERF domain complement(232539..233249) Methylobacterium extorquens DM4 8196261 YP_003065960.1 CDS METDI0226 NC_012988.1 233465 233749 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(233465..233749) Methylobacterium extorquens DM4 8190699 YP_003065961.1 CDS METDI0227 NC_012988.1 233746 234264 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(233746..234264) Methylobacterium extorquens DM4 8190700 YP_003065962.1 CDS METDI0228 NC_012988.1 234279 234455 D Evidence 6 : Doubtful CDS; hypothetical protein 234279..234455 Methylobacterium extorquens DM4 8190701 YP_003065963.1 CDS METDI0229 NC_012988.1 234854 236551 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AAA ATPase domain protein 234854..236551 Methylobacterium extorquens DM4 8190702 YP_003065964.1 CDS METDI0230 NC_012988.1 236548 236793 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 236548..236793 Methylobacterium extorquens DM4 8190703 YP_003065965.1 CDS METDI0231 NC_012988.1 236778 237386 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 236778..237386 Methylobacterium extorquens DM4 8190704 YP_003065966.1 CDS METDI0232 NC_012988.1 237422 238006 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 237422..238006 Methylobacterium extorquens DM4 8190705 YP_003065967.1 CDS METDI0233 NC_012988.1 238003 238437 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 238003..238437 Methylobacterium extorquens DM4 8190706 YP_003065968.1 CDS METDI0236 NC_012988.1 239025 239336 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 239025..239336 Methylobacterium extorquens DM4 8190709 YP_003065969.1 CDS METDI0238 NC_012988.1 239600 239803 D Evidence 6 : Doubtful CDS; hypothetical protein 239600..239803 Methylobacterium extorquens DM4 8190710 YP_003065970.1 CDS METDI0239 NC_012988.1 239861 240118 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(239861..240118) Methylobacterium extorquens DM4 8190711 YP_003065971.1 CDS METDI0241 NC_012988.1 240928 241275 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 240928..241275 Methylobacterium extorquens DM4 8190712 YP_003065972.1 CDS METDI0242 NC_012988.1 241338 241586 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 241338..241586 Methylobacterium extorquens DM4 8190713 YP_003065973.1 CDS METDI0243 NC_012988.1 241763 241828 D Evidence 6 : Doubtful CDS; hypothetical protein 241763..241828 Methylobacterium extorquens DM4 8190714 YP_003065974.1 CDS METDI0244 NC_012988.1 241953 242165 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 241953..242165 Methylobacterium extorquens DM4 8190715 YP_003065975.1 CDS METDI0246 NC_012988.1 242489 242698 R Evidence 6 : Doubtful CDS; hypothetical protein complement(242489..242698) Methylobacterium extorquens DM4 8190717 YP_003065976.1 CDS METDI0247 NC_012988.1 242673 244754 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase and two component hybrid sensor and regulator; putative membrane protein 242673..244754 Methylobacterium extorquens DM4 8190718 YP_003065977.1 CDS METDI0248 NC_012988.1 244812 245063 D Evidence 6 : Doubtful CDS; hypothetical protein 244812..245063 Methylobacterium extorquens DM4 8190719 YP_003065978.1 CDS METDI0249 NC_012988.1 245176 246444 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275; Product type e : enzyme; signal transduction histidine kinase; GAF domain 245176..246444 Methylobacterium extorquens DM4 8190720 YP_003065979.1 CDS METDI0250 NC_012988.1 246551 246742 R Evidence 6 : Doubtful CDS; hypothetical protein complement(246551..246742) Methylobacterium extorquens DM4 8190721 YP_003065980.1 CDS METDI0251 NC_012988.1 246739 247050 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(246739..247050) Methylobacterium extorquens DM4 8190722 YP_003065981.1 CDS METDI0252 NC_012988.1 247242 248813 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF motif) complement(247242..248813) Methylobacterium extorquens DM4 8190723 YP_003065982.1 CDS METDI0253 NC_012988.1 249502 250470 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family complement(249502..250470) Methylobacterium extorquens DM4 8190724 YP_003065983.1 CDS acrB NC_012988.1 250603 253731 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; Hydrophobe/Amphiphile Efflux-1 (HAE1) complement(250603..253731) Methylobacterium extorquens DM4 8190725 YP_003065984.1 CDS METDI0255 NC_012988.1 253771 254802 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15047512, 8878035; Product type t : transporter; RND efflux transporter, membrane fusion protein subunit complement(253771..254802) Methylobacterium extorquens DM4 8195054 YP_003065985.1 CDS METDI0256 NC_012988.1 255340 255819 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative molecular chaperone, heat shock Hsp20 family 255340..255819 Methylobacterium extorquens DM4 8190726 YP_003065986.1 CDS METDI0257 NC_012988.1 255819 256688 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, Crp/Fnr family 255819..256688 Methylobacterium extorquens DM4 8190727 YP_003065987.1 CDS METDI0258 NC_012988.1 256702 257520 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative Universal stress protein, UspA complement(256702..257520) Methylobacterium extorquens DM4 8190728 YP_003065988.1 CDS METDI0263 NC_012988.1 258580 258957 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(258580..258957) Methylobacterium extorquens DM4 8190731 YP_003065989.1 CDS METDI0264 NC_012988.1 258954 259331 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(258954..259331) Methylobacterium extorquens DM4 8190732 YP_003065990.1 CDS METDI0265 NC_012988.1 259399 259638 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative biotin/lipoyl attachment domain complement(259399..259638) Methylobacterium extorquens DM4 8190733 YP_003065991.1 CDS METDI0266 NC_012988.1 259833 260351 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 259833..260351 Methylobacterium extorquens DM4 8190734 YP_003065992.1 CDS METDI0267 NC_012988.1 260435 260650 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 260435..260650 Methylobacterium extorquens DM4 8190735 YP_003065993.1 CDS METDI0268 NC_012988.1 260660 260917 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 260660..260917 Methylobacterium extorquens DM4 8190736 YP_003065994.1 CDS METDI0269 NC_012988.1 260914 262245 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative manganese transporter 260914..262245 Methylobacterium extorquens DM4 8190737 YP_003065995.1 CDS METDI0270 NC_012988.1 262311 262763 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 262311..262763 Methylobacterium extorquens DM4 8190738 YP_003065996.1 CDS METDI0271 NC_012988.1 262813 263460 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pt : putative transporter; hypothetical protein 262813..263460 Methylobacterium extorquens DM4 8190739 YP_003065997.1 CDS METDI0272 NC_012988.1 263547 264356 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 263547..264356 Methylobacterium extorquens DM4 8190740 YP_003065998.1 CDS METDI0273 NC_012988.1 264357 264632 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 264357..264632 Methylobacterium extorquens DM4 8190741 YP_003065999.1 CDS METDI0274 NC_012988.1 264698 265558 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(264698..265558) Methylobacterium extorquens DM4 8190742 YP_003066000.1 CDS METDI0275 NC_012988.1 265574 265906 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(265574..265906) Methylobacterium extorquens DM4 8190743 YP_003066001.1 CDS METDI0276 NC_012988.1 265906 266721 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(265906..266721) Methylobacterium extorquens DM4 8190744 YP_003066002.1 CDS METDI0277 NC_012988.1 266800 267000 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(266800..267000) Methylobacterium extorquens DM4 8190745 YP_003066003.1 CDS METDI0278 NC_012988.1 267269 267487 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 267269..267487 Methylobacterium extorquens DM4 8190746 YP_003066004.1 CDS METDI0279 NC_012988.1 267313 267648 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 267313..267648 Methylobacterium extorquens DM4 8190747 YP_003066005.1 CDS METDI0280 NC_012988.1 267623 268219 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Cytochrome b561 (Cytochrome b-561) 267623..268219 Methylobacterium extorquens DM4 8190748 YP_003066006.1 CDS METDI0281 NC_012988.1 268225 268920 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 268225..268920 Methylobacterium extorquens DM4 8190749 YP_003066007.1 CDS METDI0282 NC_012988.1 268930 269139 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 268930..269139 Methylobacterium extorquens DM4 8190750 YP_003066008.1 CDS METDI0283 NC_012988.1 269220 270203 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1735726; Product type pe : putative enzyme; putative Zn-containing alcohol dehydrogenase (ADH) complement(269220..270203) Methylobacterium extorquens DM4 8190751 YP_003066009.1 CDS METDI0284 NC_012988.1 270213 270860 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(270213..270860) Methylobacterium extorquens DM4 8190752 YP_003066010.1 CDS METDI0285 NC_012988.1 270890 271090 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(270890..271090) Methylobacterium extorquens DM4 8190753 YP_003066011.1 CDS xfp NC_012988.1 271224 273809 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11292814, 11823225; Product type e : enzyme; putative phosphoketolase 271224..273809 Methylobacterium extorquens DM4 8190754 YP_003066012.1 CDS METDI0287 NC_012988.1 273940 274137 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 273940..274137 Methylobacterium extorquens DM4 8196339 YP_003066013.1 CDS clpB NC_012988.1 274308 276932 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor; protein disaggregation chaperone 274308..276932 Methylobacterium extorquens DM4 8190755 YP_003066014.1 CDS METDI0289 NC_012988.1 277549 278454 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; Chaperone DnaJ domain protein, putative heat shock protein 277549..278454 Methylobacterium extorquens DM4 8195169 YP_003066015.1 CDS METDI0290 NC_012988.1 278458 278760 D Evidence 4 : Homologs of previously reported genes of unknown function; conserved DnaJ-associated protein of unknown function; putative transcriptional regulator 278458..278760 Methylobacterium extorquens DM4 8190756 YP_003066016.1 CDS METDI0291 NC_012988.1 278757 279098 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 278757..279098 Methylobacterium extorquens DM4 8190757 YP_003066017.1 CDS METDI0292 NC_012988.1 278944 280791 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative poly-beta-hydroxyalkanoate synthase (phbC) 278944..280791 Methylobacterium extorquens DM4 8190758 YP_003066018.1 CDS fabI NC_012988.1 280788 281570 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 280788..281570 Methylobacterium extorquens DM4 8190759 YP_003066019.1 CDS METDI0294 NC_012988.1 281586 282983 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; bifunctional enoyl-CoA hydratase/phosphate acetyltransferase 281586..282983 Methylobacterium extorquens DM4 8195347 YP_003066020.1 CDS METDI0295 NC_012988.1 282980 284167 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetate kinase (ackA) 282980..284167 Methylobacterium extorquens DM4 8190760 YP_003066021.1 CDS METDI0297 NC_012988.1 284876 285352 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(284876..285352) Methylobacterium extorquens DM4 8190762 YP_003066022.1 CDS METDI0298 NC_012988.1 285363 286013 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein complement(285363..286013) Methylobacterium extorquens DM4 8190763 YP_003066023.1 CDS METDI0299 NC_012988.1 286067 286411 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(286067..286411) Methylobacterium extorquens DM4 8190764 YP_003066024.1 CDS METDI0300 NC_012988.1 286572 286970 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 286572..286970 Methylobacterium extorquens DM4 8190765 YP_003066025.1 CDS METDI0301 NC_012988.1 286936 289653 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Cation-transporting ATPase 286936..289653 Methylobacterium extorquens DM4 8190766 YP_003066026.1 CDS METDI0302 NC_012988.1 289760 290620 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 289760..290620 Methylobacterium extorquens DM4 8190767 YP_003066027.1 CDS METDI0303 NC_012988.1 290982 291305 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(290982..291305) Methylobacterium extorquens DM4 8190768 YP_003066028.1 CDS METDI0304 NC_012988.1 291565 292029 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(291565..292029) Methylobacterium extorquens DM4 8190769 YP_003066029.1 CDS fixK2 NC_012988.1 292124 292810 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; nitrogen fixation transcriptional regulator fixK2, Crp/Fnr family complement(292124..292810) Methylobacterium extorquens DM4 8190770 YP_003066030.1 CDS METDI0306 NC_012988.1 292934 293206 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(292934..293206) Methylobacterium extorquens DM4 8195380 YP_003066031.1 CDS METDI0307 NC_012988.1 293242 293322 R Evidence 6 : Doubtful CDS; hypothetical protein complement(293242..293322) Methylobacterium extorquens DM4 8190771 YP_003066032.1 CDS METDI0308 NC_012988.1 293319 293534 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(293319..293534) Methylobacterium extorquens DM4 8190772 YP_003066033.1 CDS METDI0309 NC_012988.1 293766 294089 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(293766..294089) Methylobacterium extorquens DM4 8190773 YP_003066034.1 CDS METDI0310 NC_012988.1 294004 294216 R Evidence 6 : Doubtful CDS; hypothetical protein complement(294004..294216) Methylobacterium extorquens DM4 8190774 YP_003066035.1 CDS METDI0311 NC_012988.1 294379 294663 D Evidence 6 : Doubtful CDS; hypothetical protein 294379..294663 Methylobacterium extorquens DM4 8190775 YP_003066036.1 CDS METDI0312 NC_012988.1 294654 294839 D Evidence 6 : Doubtful CDS; hypothetical protein 294654..294839 Methylobacterium extorquens DM4 8190776 YP_003066037.1 CDS METDI0313 NC_012988.1 294917 295036 R Evidence 6 : Doubtful CDS; hypothetical protein complement(294917..295036) Methylobacterium extorquens DM4 8190777 YP_003066038.1 CDS METDI0314 NC_012988.1 295151 295933 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi17, IS5 family complement(295151..295933) Methylobacterium extorquens DM4 8190778 YP_003066039.1 CDS METDI0315 NC_012988.1 296144 297094 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi8, IS481 family complement(296144..297094) Methylobacterium extorquens DM4 8190779 YP_003066040.1 CDS METDI0316 NC_012988.1 297231 298565 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi6, IS1182 family complement(297231..298565) Methylobacterium extorquens DM4 8190780 YP_003066041.1 CDS METDI0317 NC_012988.1 299121 299513 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative two component response regulator (FixJ domain-like) complement(299121..299513) Methylobacterium extorquens DM4 8190781 YP_003066042.1 CDS fixJ NC_012988.1 299603 300211 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; two component transcriptional regulator, LuxR family; putative nitrogen fixation transcriptional regulator FixJ complement(299603..300211) Methylobacterium extorquens DM4 8190782 YP_003066043.1 CDS fixL NC_012988.1 300201 301751 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; two component low oxygen sensor histidine kinase with PAS domains; FixL complement(300201..301751) Methylobacterium extorquens DM4 8195377 YP_003066044.1 CDS METDI0320 NC_012988.1 302072 302932 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative universal stress protein, UspA 302072..302932 Methylobacterium extorquens DM4 8195382 YP_003066045.1 CDS METDI0321 NC_012988.1 302949 303161 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 302949..303161 Methylobacterium extorquens DM4 8190783 YP_003066046.1 CDS METDI0322 NC_012988.1 303248 303583 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome c, class I complement(303248..303583) Methylobacterium extorquens DM4 8190784 YP_003066047.1 CDS METDI0323 NC_012988.1 303583 304395 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Universal stress protein, UspA complement(303583..304395) Methylobacterium extorquens DM4 8190785 YP_003066048.1 CDS METDI0324 NC_012988.1 304490 306415 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11481432; Product type pt : putative transporter; putative cation transport P-type ATPase complement(304490..306415) Methylobacterium extorquens DM4 8190786 YP_003066049.1 CDS METDI0325 NC_012988.1 306792 307625 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi8, IS481 family complement(306792..307625) Methylobacterium extorquens DM4 8190787 YP_003066050.1 CDS METDI0326 NC_012988.1 308146 310359 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sensory box-containing diguanylate cyclase/phosphodiesterase, PAS/PAC, GGDEF and EAL domains 308146..310359 Methylobacterium extorquens DM4 8190788 YP_003066051.1 CDS METDI0327 NC_012988.1 310593 310763 R Evidence 6 : Doubtful CDS; hypothetical protein complement(310593..310763) Methylobacterium extorquens DM4 8190789 YP_003066052.1 CDS METDI0328 NC_012988.1 311020 311472 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 311020..311472 Methylobacterium extorquens DM4 8190790 YP_003066053.1 CDS METDI0329 NC_012988.1 311743 312966 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative secretion protein precursor, putative RND family efflux protein 311743..312966 Methylobacterium extorquens DM4 8190791 YP_003066054.1 CDS czcA NC_012988.1 312970 316260 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7766206; Product type t : transporter; Cation efflux system protein czcA 312970..316260 Methylobacterium extorquens DM4 8190792 YP_003066055.1 CDS METDI0331 NC_012988.1 316411 316707 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(316411..316707) Methylobacterium extorquens DM4 8195264 YP_003066056.1 CDS METDI0332 NC_012988.1 316833 319127 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11587643; Product type pe : putative enzyme; putative glycosyl hydrolase complement(316833..319127) Methylobacterium extorquens DM4 8190793 YP_003066057.1 CDS METDI0333 NC_012988.1 319124 319894 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase-like hydrolase complement(319124..319894) Methylobacterium extorquens DM4 8190794 YP_003066058.1 CDS METDI0334 NC_012988.1 319920 320309 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 319920..320309 Methylobacterium extorquens DM4 8190795 YP_003066059.1 CDS METDI0335 NC_012988.1 321047 321370 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, ArsR family 321047..321370 Methylobacterium extorquens DM4 8190796 YP_003066060.1 CDS METDI0337 NC_012988.1 321758 323071 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase precursor complement(321758..323071) Methylobacterium extorquens DM4 8190797 YP_003066061.1 CDS METDI0338 NC_012988.1 323068 323730 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; DNA-binding response regulator in two-component regulatory system complement(323068..323730) Methylobacterium extorquens DM4 8190798 YP_003066062.1 CDS METDI0339 NC_012988.1 323838 325247 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative thiol:disulfide interchange protein 323838..325247 Methylobacterium extorquens DM4 8190799 YP_003066063.1 CDS METDI0340 NC_012988.1 325015 325611 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thiol:disulfide interchange protein 325015..325611 Methylobacterium extorquens DM4 8190800 YP_003066064.1 CDS METDI0341 NC_012988.1 325645 326280 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thioredoxin domain protein precursor 325645..326280 Methylobacterium extorquens DM4 8190801 YP_003066065.1 CDS METDI0342 NC_012988.1 326277 327128 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 326277..327128 Methylobacterium extorquens DM4 8190802 YP_003066066.1 CDS METDI0343 NC_012988.1 327112 327576 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 327112..327576 Methylobacterium extorquens DM4 8190803 YP_003066067.1 CDS METDI0344 NC_012988.1 327612 328070 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(327612..328070) Methylobacterium extorquens DM4 8190804 YP_003066068.1 CDS METDI0345 NC_012988.1 328235 328660 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 328235..328660 Methylobacterium extorquens DM4 8190805 YP_003066069.1 CDS METDI0346 NC_012988.1 328664 329113 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 328664..329113 Methylobacterium extorquens DM4 8190806 YP_003066070.1 CDS METDI0347 NC_012988.1 329113 329919 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 329113..329919 Methylobacterium extorquens DM4 8190807 YP_003066071.1 CDS METDI0348 NC_012988.1 329937 330848 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; beta-lactamase domain protein, putative hydroxyacylglutathione hydrolase 329937..330848 Methylobacterium extorquens DM4 8190808 YP_003066072.1 CDS METDI0349 NC_012988.1 331090 331533 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8652661; Product type pe : putative enzyme; hypothetical protein complement(331090..331533) Methylobacterium extorquens DM4 8190809 YP_003066073.1 CDS METDI0350 NC_012988.1 331650 332534 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; beta-lactamase domain protein complement(331650..332534) Methylobacterium extorquens DM4 8190810 YP_003066074.1 CDS METDI0351 NC_012988.1 332572 332784 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(332572..332784) Methylobacterium extorquens DM4 8190811 YP_003066075.1 CDS METDI0352 NC_012988.1 333170 335275 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11114914; Product type r : regulator; methyl-accepting chemotaxis receptor/sensory transducer precursor; histidine kinase HAMP domain complement(333170..335275) Methylobacterium extorquens DM4 8190812 YP_003066076.1 CDS phnC NC_012988.1 335773 336582 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1840580, 2155230, 93122525, 93273711, 93328121, 9650256; Product type t : transporter; phosphonate transport protein (ABC superfamily, atp_bind) 335773..336582 Methylobacterium extorquens DM4 8190813 YP_003066077.1 CDS ptxB NC_012988.1 336595 337467 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9791102; Product type pt : putative transporter; putative phosphonate transport system substrate-binding protein 336595..337467 Methylobacterium extorquens DM4 8195860 YP_003066078.1 CDS ptxC NC_012988.1 337471 338304 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9791102; Product type t : transporter; putative phosphate permease component of ATP-dependent phosphate uptake system 337471..338304 Methylobacterium extorquens DM4 8195919 YP_003066079.1 CDS ptxD NC_012988.1 338313 339332 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11278981, 9791102; Product type e : enzyme; Phosphonate dehydrogenase (NAD-dependent phosphite dehydrogenase) 338313..339332 Methylobacterium extorquens DM4 8195920 YP_003066080.1 CDS METDI0357 NC_012988.1 339358 340218 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15640200; Product type pr : putative regulator; putative transcriptional regulator, LysR family 339358..340218 Methylobacterium extorquens DM4 8195921 YP_003066081.1 CDS METDI0362 NC_012988.1 341136 341948 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7619830; Product type pc : putative carrier; putative cytochrome c complement(341136..341948) Methylobacterium extorquens DM4 8190817 YP_003066082.1 CDS METDI0363 NC_012988.1 341945 343567 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10775261; Product type pe : putative enzyme; putative Cytochrome c oxidase, subunit I complement(341945..343567) Methylobacterium extorquens DM4 8190818 YP_003066083.1 CDS METDI0364 NC_012988.1 343557 344120 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10775261; Product type pe : putative enzyme; putative cytochrome c oxidase, subunit II (cbaB) complement(343557..344120) Methylobacterium extorquens DM4 8190819 YP_003066084.1 CDS METDI0365 NC_012988.1 344133 344309 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(344133..344309) Methylobacterium extorquens DM4 8190820 YP_003066085.1 CDS METDI0366 NC_012988.1 344314 345570 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9352901; Product type pc : putative carrier; putative cytochrome c, putative exported protein complement(344314..345570) Methylobacterium extorquens DM4 8190821 YP_003066086.1 CDS METDI0367 NC_012988.1 345582 346181 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome c complement(345582..346181) Methylobacterium extorquens DM4 8190822 YP_003066087.1 CDS METDI0368 NC_012988.1 346671 347360 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11882718, 8759861; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family 346671..347360 Methylobacterium extorquens DM4 8190823 YP_003066088.1 CDS METDI0369 NC_012988.1 347567 347797 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 347567..347797 Methylobacterium extorquens DM4 8190824 YP_003066089.1 CDS METDI0370 NC_012988.1 347733 348056 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(347733..348056) Methylobacterium extorquens DM4 8190825 YP_003066090.1 CDS METDI0371 NC_012988.1 348081 348326 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(348081..348326) Methylobacterium extorquens DM4 8190826 YP_003066091.1 CDS METDI0372 NC_012988.1 348595 348990 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Response regulator; CheY-like protein 348595..348990 Methylobacterium extorquens DM4 8190827 YP_003066092.1 CDS METDI0373 NC_012988.1 349296 349742 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 349296..349742 Methylobacterium extorquens DM4 8190828 YP_003066093.1 CDS METDI0374 NC_012988.1 349865 350194 D Evidence 6 : Doubtful CDS; hypothetical protein 349865..350194 Methylobacterium extorquens DM4 8190829 YP_003066094.1 CDS METDI0375 NC_012988.1 350423 350635 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(350423..350635) Methylobacterium extorquens DM4 8190830 YP_003066095.1 CDS METDI0376 NC_012988.1 350656 350970 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(350656..350970) Methylobacterium extorquens DM4 8190831 YP_003066096.1 CDS METDI0377 NC_012988.1 351013 351750 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(351013..351750) Methylobacterium extorquens DM4 8190832 YP_003066097.1 CDS METDI0378 NC_012988.1 351847 352830 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, aldo/keto reductase family complement(351847..352830) Methylobacterium extorquens DM4 8190833 YP_003066098.1 CDS METDI0379 NC_012988.1 352999 353895 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family 352999..353895 Methylobacterium extorquens DM4 8190834 YP_003066099.1 CDS METDI0380 NC_012988.1 354410 354616 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 354410..354616 Methylobacterium extorquens DM4 8190835 YP_003066100.1 CDS METDI0381 NC_012988.1 354761 354979 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 354761..354979 Methylobacterium extorquens DM4 8190836 YP_003066101.1 CDS METDI0382 NC_012988.1 355367 356248 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(355367..356248) Methylobacterium extorquens DM4 8190837 YP_003066102.1 CDS METDI0383 NC_012988.1 356298 356849 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10383985, 1472501, 7876185, 8704959; hypothetical protein complement(356298..356849) Methylobacterium extorquens DM4 8190838 YP_003066103.1 CDS METDI0384 NC_012988.1 357055 357273 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(357055..357273) Methylobacterium extorquens DM4 8190839 YP_003066104.1 CDS METDI0385 NC_012988.1 357400 358680 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14727089, 3009477, 7984428, 8140616; Product type pt : putative transporter; putative transport protein, SulP family complement(357400..358680) Methylobacterium extorquens DM4 8190840 YP_003066105.1 CDS METDI0386 NC_012988.1 359408 360433 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; histone deacetylase family protein 359408..360433 Methylobacterium extorquens DM4 8190841 YP_003066106.1 CDS METDI0389 NC_012988.1 361106 361333 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(361106..361333) Methylobacterium extorquens DM4 8190842 YP_003066107.1 CDS METDI0390 NC_012988.1 361463 365764 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 361463..365764 Methylobacterium extorquens DM4 8190843 YP_003066108.1 CDS METDI0391 NC_012988.1 365722 366657 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(365722..366657) Methylobacterium extorquens DM4 8190844 YP_003066109.1 CDS METDI0392 NC_012988.1 367017 367376 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 367017..367376 Methylobacterium extorquens DM4 8190845 YP_003066110.1 CDS METDI0393 NC_012988.1 367547 368476 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 367547..368476 Methylobacterium extorquens DM4 8190846 YP_003066111.1 CDS METDI0394 NC_012988.1 368481 368801 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 368481..368801 Methylobacterium extorquens DM4 8190847 YP_003066112.1 CDS METDI0395 NC_012988.1 368954 370117 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(368954..370117) Methylobacterium extorquens DM4 8190848 YP_003066113.1 CDS METDI0396 NC_012988.1 370027 370917 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(370027..370917) Methylobacterium extorquens DM4 8190849 YP_003066114.1 CDS METDI0397 NC_012988.1 371059 371400 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(371059..371400) Methylobacterium extorquens DM4 8190850 YP_003066115.1 CDS METDI0398 NC_012988.1 371672 372160 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(371672..372160) Methylobacterium extorquens DM4 8190851 YP_003066116.1 CDS METDI0399 NC_012988.1 372685 373371 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 372685..373371 Methylobacterium extorquens DM4 8190852 YP_003066117.1 CDS METDI0400 NC_012988.1 373641 374003 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 373641..374003 Methylobacterium extorquens DM4 8190853 YP_003066118.1 CDS METDI0401 NC_012988.1 373990 377409 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620739; Product type pe : putative enzyme; putative ATP-dependent DNA helicase 373990..377409 Methylobacterium extorquens DM4 8190854 YP_003066119.1 CDS METDI0402 NC_012988.1 377446 378249 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 377446..378249 Methylobacterium extorquens DM4 8190855 YP_003066120.1 CDS METDI0403 NC_012988.1 378249 379643 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 378249..379643 Methylobacterium extorquens DM4 8190856 YP_003066121.1 CDS METDI0404 NC_012988.1 379640 379981 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 379640..379981 Methylobacterium extorquens DM4 8190857 YP_003066122.1 CDS METDI0405 NC_012988.1 380060 380779 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(380060..380779) Methylobacterium extorquens DM4 8190858 YP_003066123.1 CDS METDI0410 NC_012988.1 382848 383009 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(382848..383009) Methylobacterium extorquens DM4 8190862 YP_003066124.1 CDS METDI0411 NC_012988.1 383292 383573 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 383292..383573 Methylobacterium extorquens DM4 8190863 YP_003066125.1 CDS METDI0412 NC_012988.1 383991 384380 D Evidence 5 : No homology to any previously reported sequences; PubMedId : 11055911; hypothetical protein 383991..384380 Methylobacterium extorquens DM4 8190864 YP_003066126.1 CDS METDI0414 NC_012988.1 384455 385291 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(384455..385291) Methylobacterium extorquens DM4 8190865 YP_003066127.1 CDS METDI0415 NC_012988.1 385356 385889 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(385356..385889) Methylobacterium extorquens DM4 8190866 YP_003066128.1 CDS METDI0416 NC_012988.1 386043 386375 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 386043..386375 Methylobacterium extorquens DM4 8190867 YP_003066129.1 CDS METDI0417 NC_012988.1 386372 386596 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 386372..386596 Methylobacterium extorquens DM4 8190868 YP_003066130.1 CDS METDI0418 NC_012988.1 386593 387198 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 386593..387198 Methylobacterium extorquens DM4 8190869 YP_003066131.1 CDS METDI0419 NC_012988.1 387198 387485 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12767982; hypothetical protein 387198..387485 Methylobacterium extorquens DM4 8190870 YP_003066132.1 CDS METDI0420 NC_012988.1 387559 387984 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 387559..387984 Methylobacterium extorquens DM4 8190871 YP_003066133.1 CDS METDI0421 NC_012988.1 388077 388292 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 388077..388292 Methylobacterium extorquens DM4 8190872 YP_003066134.1 CDS METDI0422 NC_012988.1 388421 388846 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 388421..388846 Methylobacterium extorquens DM4 8190873 YP_003066135.1 CDS METDI0423 NC_012988.1 388958 389491 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 388958..389491 Methylobacterium extorquens DM4 8190874 YP_003066136.1 CDS METDI0424 NC_012988.1 389586 390119 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 389586..390119 Methylobacterium extorquens DM4 8190875 YP_003066137.1 CDS METDI0425 NC_012988.1 390116 390700 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphohydrolase/phosphoesterase complement(390116..390700) Methylobacterium extorquens DM4 8190876 YP_003066138.1 CDS METDI0426 NC_012988.1 390794 392215 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative phage integrase, putative integrase/resolvase/recombinase protein, putative DNA integration/recombination/inversion protein complement(390794..392215) Methylobacterium extorquens DM4 8190877 YP_003066139.1 CDS METDI0427 NC_012988.1 392837 394297 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LuxR family 392837..394297 Methylobacterium extorquens DM4 8190878 YP_003066140.1 CDS METDI0428 NC_012988.1 394393 394548 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10376822, 11988534; hypothetical protein 394393..394548 Methylobacterium extorquens DM4 8190879 YP_003066141.1 CDS METDI0429 NC_012988.1 394607 394948 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 394607..394948 Methylobacterium extorquens DM4 8190880 YP_003066142.1 CDS METDI0430 NC_012988.1 394992 395903 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 394992..395903 Methylobacterium extorquens DM4 8190881 YP_003066143.1 CDS METDI0431 NC_012988.1 395994 396197 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 395994..396197 Methylobacterium extorquens DM4 8190882 YP_003066144.1 CDS METDI0432 NC_012988.1 396272 396655 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 396272..396655 Methylobacterium extorquens DM4 8190883 YP_003066145.1 CDS METDI0433 NC_012988.1 396876 397796 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(396876..397796) Methylobacterium extorquens DM4 8190884 YP_003066146.1 CDS argE NC_012988.1 397807 398982 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10684608; Product type e : enzyme; Acetylornithine deacetylase complement(397807..398982) Methylobacterium extorquens DM4 8190885 YP_003066147.1 CDS apaG NC_012988.1 398979 399371 R protein associated with Co2+ and Mg2+ efflux; ApaG complement(398979..399371) Methylobacterium extorquens DM4 8195086 YP_003066148.1 CDS METDI0436 NC_012988.1 399539 399988 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 399539..399988 Methylobacterium extorquens DM4 8195076 YP_003066149.1 CDS dcd NC_012988.1 399985 401103 D Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 399985..401103 Methylobacterium extorquens DM4 8190886 YP_003066150.1 CDS METDI0438 NC_012988.1 401150 402070 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transport protein complement(401150..402070) Methylobacterium extorquens DM4 8195275 YP_003066151.1 CDS METDI0439 NC_012988.1 402149 402886 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16926146; Product type pf : putative factor; putative Molybdopterin binding, CinA-related complement(402149..402886) Methylobacterium extorquens DM4 8190887 YP_003066152.1 CDS sfsA NC_012988.1 402970 403716 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11259647; Product type r : regulator; sugar fermentation stimulation protein 402970..403716 Methylobacterium extorquens DM4 8190888 YP_003066153.1 CDS METDI0441 NC_012988.1 403673 404614 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Methyltransferase FkbM complement(403673..404614) Methylobacterium extorquens DM4 8196114 YP_003066154.1 CDS METDI0442 NC_012988.1 404658 405434 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16926146; Product type pe : putative enzyme; putative alpha/beta hydrolase 404658..405434 Methylobacterium extorquens DM4 8190889 YP_003066155.1 CDS METDI0443 NC_012988.1 405573 406037 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 405573..406037 Methylobacterium extorquens DM4 8190890 YP_003066156.1 CDS METDI0444 NC_012988.1 406061 406840 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC-2 transporter, permease complement(406061..406840) Methylobacterium extorquens DM4 8190891 YP_003066157.1 CDS METDI0445 NC_012988.1 406837 407763 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16738553, 8202364, 9278503; Product type pt : putative transporter; putative ABC transporter, ATPase complement(406837..407763) Methylobacterium extorquens DM4 8190892 YP_003066158.1 CDS METDI0446 NC_012988.1 408084 410081 R Evidence 2b : Function of strongly homologous gene; Product type pc : putative carrier; 4Fe-4S ferredoxin, iron-sulfur binding complement(408084..410081) Methylobacterium extorquens DM4 8190893 YP_003066159.1 CDS METDI0447 NC_012988.1 410264 411022 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 410264..411022 Methylobacterium extorquens DM4 8190894 YP_003066160.1 CDS METDI0448 NC_012988.1 411019 411585 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 411019..411585 Methylobacterium extorquens DM4 8190895 YP_003066161.1 CDS METDI0449 NC_012988.1 411582 412592 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 411582..412592 Methylobacterium extorquens DM4 8190896 YP_003066162.1 CDS METDI0450 NC_012988.1 412601 413119 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 412601..413119 Methylobacterium extorquens DM4 8190897 YP_003066163.1 CDS METDI0451 NC_012988.1 413116 413826 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 413116..413826 Methylobacterium extorquens DM4 8190898 YP_003066164.1 CDS METDI0452 NC_012988.1 413914 414549 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Cytoplasmic chaperone TorD 413914..414549 Methylobacterium extorquens DM4 8190899 YP_003066165.1 CDS METDI0453 NC_012988.1 414623 414871 D Evidence 2b : Function of strongly homologous gene; hypothetical protein 414623..414871 Methylobacterium extorquens DM4 8190900 YP_003066166.1 CDS fdh3A NC_012988.1 414879 417821 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase alpha subunit precursor (tat pathway signal) 414879..417821 Methylobacterium extorquens DM4 8190901 YP_003066167.1 CDS fdh3B NC_012988.1 417839 418435 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; Formate dehydrogenase iron-sulfur (beta) subunit 417839..418435 Methylobacterium extorquens DM4 8195366 YP_003066168.1 CDS fdh3C NC_012988.1 418504 419541 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; Formate dehydrogenase gamma (cytochrome) subunit 418504..419541 Methylobacterium extorquens DM4 8195367 YP_003066169.1 CDS METDI0457 NC_012988.1 419636 419875 D Evidence 6 : Doubtful CDS; hypothetical protein 419636..419875 Methylobacterium extorquens DM4 8195368 YP_003066170.1 CDS METDI0458 NC_012988.1 419920 420537 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 419920..420537 Methylobacterium extorquens DM4 8190902 YP_003066171.1 CDS METDI0459 NC_012988.1 420575 421168 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(420575..421168) Methylobacterium extorquens DM4 8190903 YP_003066172.1 CDS METDI0460 NC_012988.1 421488 421802 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 421488..421802 Methylobacterium extorquens DM4 8190904 YP_003066173.1 CDS METDI0461 NC_012988.1 421799 422434 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative TetR family transcriptional regulatory protein 421799..422434 Methylobacterium extorquens DM4 8190905 YP_003066174.1 CDS METDI0462 NC_012988.1 422431 423672 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative HlyD family secretion protein precursor; putative efflux transporter, membrane fusion protein subunit precursor 422431..423672 Methylobacterium extorquens DM4 8190906 YP_003066175.1 CDS METDI0463 NC_012988.1 423721 426816 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; efflux transporter (AcrB/AcrD/AcrF family multidrug efflux pump 423721..426816 Methylobacterium extorquens DM4 8190907 YP_003066176.1 CDS METDI0464 NC_012988.1 427069 427347 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(427069..427347) Methylobacterium extorquens DM4 8190908 YP_003066177.1 CDS hrcA NC_012988.1 427476 428579 R Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor complement(427476..428579) Methylobacterium extorquens DM4 8190909 YP_003066178.1 CDS METDI0466 NC_012988.1 428845 429108 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 428845..429108 Methylobacterium extorquens DM4 8195576 YP_003066179.1 CDS METDI0467 NC_012988.1 429026 429232 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 429026..429232 Methylobacterium extorquens DM4 8190910 YP_003066180.1 CDS rph NC_012988.1 429273 429986 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 429273..429986 Methylobacterium extorquens DM4 8190911 YP_003066181.1 CDS METDI0469 NC_012988.1 429983 430618 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 429983..430618 Methylobacterium extorquens DM4 8196010 YP_003066182.1 CDS yggW NC_012988.1 430868 432046 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidase 430868..432046 Methylobacterium extorquens DM4 8190912 YP_003066183.1 CDS METDI0471 NC_012988.1 432102 432335 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 432102..432335 Methylobacterium extorquens DM4 8196366 YP_003066184.1 CDS METDI0472 NC_012988.1 432332 432619 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 432332..432619 Methylobacterium extorquens DM4 8190913 YP_003066185.1 CDS METDI0473 NC_012988.1 432641 433852 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative extracellular ligand-binding receptor precursor complement(432641..433852) Methylobacterium extorquens DM4 8190914 YP_003066186.1 CDS yraL NC_012988.1 433973 434923 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase 433973..434923 Methylobacterium extorquens DM4 8190915 YP_003066187.1 CDS METDI0475 NC_012988.1 434907 435293 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 434907..435293 Methylobacterium extorquens DM4 8196378 YP_003066188.1 CDS METDI0476 NC_012988.1 435323 435712 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver complement(435323..435712) Methylobacterium extorquens DM4 8190916 YP_003066189.1 CDS METDI0477 NC_012988.1 436005 436916 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15251200; Product type t : transporter; ABC transporter, periplasmic protein, putative glycine/betaine transporter 436005..436916 Methylobacterium extorquens DM4 8190917 YP_003066190.1 CDS METDI0478 NC_012988.1 436913 438055 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, permease, putative glycine/betaine transporter 436913..438055 Methylobacterium extorquens DM4 8190918 YP_003066191.1 CDS METDI0479 NC_012988.1 438052 438780 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, permease, putative glycine/betaine transporter 438052..438780 Methylobacterium extorquens DM4 8190919 YP_003066192.1 CDS METDI0480 NC_012988.1 438787 439881 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; ErfK/YbiS/YcfS/YnhG family protein complement(438787..439881) Methylobacterium extorquens DM4 8190920 YP_003066193.1 CDS METDI0481 NC_012988.1 440003 440920 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(440003..440920) Methylobacterium extorquens DM4 8190921 YP_003066194.1 CDS dcp NC_012988.1 441118 443217 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Peptidyl-dipeptidase 441118..443217 Methylobacterium extorquens DM4 8190922 YP_003066195.1 CDS ftfL NC_012988.1 443332 445005 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 14645277; Product type e : enzyme; formate-tetrahydrofolate ligase (formyltetrahydrofolate synthetase) (FHS) (FTHFS) complement(443332..445005) Methylobacterium extorquens DM4 8195278 YP_003066196.1 CDS METDI0484 NC_012988.1 445244 445465 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12644235; Product type pc : putative carrier; putative copper ion binding protein; putative heavy metal transport/detoxification protein complement(445244..445465) Methylobacterium extorquens DM4 8195446 YP_003066197.1 CDS METDI0485 NC_012988.1 445752 447233 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 445752..447233 Methylobacterium extorquens DM4 8190923 YP_003066198.1 CDS METDI0486 NC_012988.1 447268 447495 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(447268..447495) Methylobacterium extorquens DM4 8190924 YP_003066199.1 CDS METDI0487 NC_012988.1 447666 448202 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(447666..448202) Methylobacterium extorquens DM4 8190925 YP_003066200.1 CDS METDI0488 NC_012988.1 448181 448420 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 448181..448420 Methylobacterium extorquens DM4 8190926 YP_003066201.1 CDS METDI0489 NC_012988.1 448386 448769 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) complement(448386..448769) Methylobacterium extorquens DM4 8190927 YP_003066202.1 CDS ribF NC_012988.1 449076 450089 D [Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)]; Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2985604, 9743119; Product type pe : putative enzyme; putative riboflavin biosynthesis protein ribF 449076..450089 Methylobacterium extorquens DM4 8190928 YP_003066203.1 CDS METDI0491 NC_012988.1 450280 451284 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 2-hydroxyacid dehydrogenase complement(450280..451284) Methylobacterium extorquens DM4 8195996 YP_003066204.1 CDS METDI0492 NC_012988.1 451610 452203 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 451610..452203 Methylobacterium extorquens DM4 8190929 YP_003066205.1 CDS METDI0493 NC_012988.1 452308 452808 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Ferric uptake regulator family, Irr-like protein complement(452308..452808) Methylobacterium extorquens DM4 8190930 YP_003066206.1 CDS fabA NC_012988.1 453085 453624 D catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-(acyl carrier protein) dehydratase 453085..453624 Methylobacterium extorquens DM4 8190931 YP_003066207.1 CDS fabB NC_012988.1 453785 455011 D FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase I 453785..455011 Methylobacterium extorquens DM4 8195341 YP_003066208.1 CDS METDI0496 NC_012988.1 455165 455284 D Evidence 6 : Doubtful CDS; hypothetical protein 455165..455284 Methylobacterium extorquens DM4 8195342 YP_003066209.1 CDS fabI NC_012988.1 455485 456315 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10398587, 2687243; Product type e : enzyme; Enoyl-[acyl-carrier-protein] reductase (NADH) 455485..456315 Methylobacterium extorquens DM4 8190932 YP_003066210.1 CDS fliP NC_012988.1 456383 457144 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; flagellar biosynthesis protein FliP 456383..457144 Methylobacterium extorquens DM4 8195348 YP_003066211.1 CDS METDI0499 NC_012988.1 457201 457602 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 457201..457602 Methylobacterium extorquens DM4 8195426 YP_003066212.1 CDS METDI0500 NC_012988.1 457606 460956 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(457606..460956) Methylobacterium extorquens DM4 8190933 YP_003066213.1 CDS METDI0501 NC_012988.1 461072 461503 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(461072..461503) Methylobacterium extorquens DM4 8190934 YP_003066214.1 CDS METDI0502 NC_012988.1 461657 463804 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Peptidase S9, prolyl oligopeptidase complement(461657..463804) Methylobacterium extorquens DM4 8190935 YP_003066215.1 CDS mucR NC_012988.1 464233 464670 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10656595, 11481430, 7756693; Product type r : regulator; Transcriptional regulatory protein mucR 464233..464670 Methylobacterium extorquens DM4 8190936 YP_003066216.1 CDS METDI0504 NC_012988.1 464821 465015 D Evidence 6 : Doubtful CDS; hypothetical protein 464821..465015 Methylobacterium extorquens DM4 8195735 YP_003066217.1 CDS METDI0505 NC_012988.1 465152 465976 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 465152..465976 Methylobacterium extorquens DM4 8190937 YP_003066218.1 CDS METDI0506 NC_012988.1 466014 466442 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative sulfur acceptor protein sufE complement(466014..466442) Methylobacterium extorquens DM4 8190938 YP_003066219.1 CDS METDI0507 NC_012988.1 466531 467610 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(466531..467610) Methylobacterium extorquens DM4 8190939 YP_003066220.1 CDS METDI0508 NC_012988.1 467763 471431 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor hybrid histidine kinase with multiple PAS/PAC, GAF and response regulator receiver domains complement(467763..471431) Methylobacterium extorquens DM4 8190940 YP_003066221.1 CDS METDI0509 NC_012988.1 472118 472627 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 472118..472627 Methylobacterium extorquens DM4 8190941 YP_003066222.1 CDS METDI0510 NC_012988.1 472743 472907 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 472743..472907 Methylobacterium extorquens DM4 8190942 YP_003066223.1 CDS METDI0511 NC_012988.1 472954 473376 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10882093; Product type pe : putative enzyme; putative lactoylglutathione lyase complement(472954..473376) Methylobacterium extorquens DM4 8190943 YP_003066224.1 CDS METDI0512 NC_012988.1 473817 474725 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 473817..474725 Methylobacterium extorquens DM4 8190944 YP_003066225.1 CDS pepN NC_012988.1 474804 477440 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aminopeptidase N 474804..477440 Methylobacterium extorquens DM4 8190945 YP_003066226.1 CDS METDI0514 NC_012988.1 477626 479986 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative PAS sensor signal transduction histidine kinase 477626..479986 Methylobacterium extorquens DM4 8195844 YP_003066227.1 CDS rocF NC_012988.1 480393 481319 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2806247, 7540694, 9375792; Product type e : enzyme; arginase (arginine amidinase) 480393..481319 Methylobacterium extorquens DM4 8190946 YP_003066228.1 CDS zwf NC_012988.1 481412 482890 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17631881, 9537370; Product type e : enzyme; Glucose-6-phosphate 1-dehydrogenase (G6PD) complement(481412..482890) Methylobacterium extorquens DM4 8196008 YP_003066229.1 CDS METDI0518 NC_012988.1 483161 483598 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(483161..483598) Methylobacterium extorquens DM4 8196381 YP_003066230.1 CDS cutA NC_012988.1 484230 484553 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7623666, 7623667, 95349397; Product type pf : putative factor; copper binding protein, copper sensitivity complement(484230..484553) Methylobacterium extorquens DM4 8190947 YP_003066231.1 CDS ppnK NC_012988.1 484659 485429 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11259647; Product type pe : putative enzyme; putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase) 484659..485429 Methylobacterium extorquens DM4 8195232 YP_003066232.1 CDS METDI0521 NC_012988.1 485498 485725 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(485498..485725) Methylobacterium extorquens DM4 8195885 YP_003066233.1 CDS rsmB NC_012988.1 485815 487179 D Evidence 2b : Function of strongly homologous gene; PubMedId : 14656444, 8412700, 8432722, 9086272, 99212225; Product type e : enzyme; 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent 485815..487179 Methylobacterium extorquens DM4 8190948 YP_003066234.1 CDS METDI0523 NC_012988.1 487239 487403 R Evidence 6 : Doubtful CDS; hypothetical protein complement(487239..487403) Methylobacterium extorquens DM4 8196089 YP_003066235.1 CDS METDI0524 NC_012988.1 487750 488784 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 487750..488784 Methylobacterium extorquens DM4 8190949 YP_003066236.1 CDS METDI0525 NC_012988.1 489158 490351 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine acetyltransferase) 489158..490351 Methylobacterium extorquens DM4 8190950 YP_003066237.1 CDS METDI0526 NC_012988.1 490412 490741 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(490412..490741) Methylobacterium extorquens DM4 8190951 YP_003066238.1 CDS fabD NC_012988.1 491087 492019 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7768883; Product type e : enzyme; malonyl-CoA-[acyl-carrier-protein] transacylase 491087..492019 Methylobacterium extorquens DM4 8190952 YP_003066239.1 CDS fabG NC_012988.1 492128 492868 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11669613, 1314802; Product type e : enzyme; 3-oxoacyl-[acyl-carrier-protein] reductase 492128..492868 Methylobacterium extorquens DM4 8195343 YP_003066240.1 CDS acpP NC_012988.1 493132 493368 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 493132..493368 Methylobacterium extorquens DM4 8195345 YP_003066241.1 CDS fabF NC_012988.1 493537 494769 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9013860, 9482715; Product type e : enzyme; 3-oxoacyl-[acyl-carrier-protein] synthase II 493537..494769 Methylobacterium extorquens DM4 8195050 YP_003066242.1 CDS METDI0532 NC_012988.1 495032 496435 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 495032..496435 Methylobacterium extorquens DM4 8195344 YP_003066243.1 CDS METDI0533 NC_012988.1 496465 497181 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase-like hydrolase complement(496465..497181) Methylobacterium extorquens DM4 8190953 YP_003066244.1 CDS METDI0534 NC_012988.1 497195 499582 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative glycoside hydrolase or sugar phosphorilase complement(497195..499582) Methylobacterium extorquens DM4 8190954 YP_003066245.1 CDS METDI0535 NC_012988.1 500447 501649 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetate kinase (ackA) 500447..501649 Methylobacterium extorquens DM4 8190955 YP_003066246.1 CDS METDI0536 NC_012988.1 501646 502677 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative membrane protein, component of efflux system 501646..502677 Methylobacterium extorquens DM4 8190956 YP_003066247.1 CDS METDI0537 NC_012988.1 502685 505423 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused tandem ATPase and permease domains 502685..505423 Methylobacterium extorquens DM4 8190957 YP_003066248.1 CDS METDI0538 NC_012988.1 505425 506624 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative ABC-2 transporter, permease 505425..506624 Methylobacterium extorquens DM4 8190958 YP_003066249.1 CDS xfp NC_012988.1 506704 509139 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11292814, 11823225; Product type e : enzyme; putative phosphoketolase 506704..509139 Methylobacterium extorquens DM4 8190959 YP_003066250.1 CDS METDI0540 NC_012988.1 509263 510393 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11756688; Product type e : enzyme; Salicylate hydroxylase (Salicylate 1-monooxygenase) 509263..510393 Methylobacterium extorquens DM4 8196340 YP_003066251.1 CDS cysA NC_012988.1 510804 511862 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2188958, 7665461, 90202710, 90264334; Product type pt : putative transporter; putative sulfate/thiosulfate transporter subunit ; ATP-binding component of ABC superfamily 510804..511862 Methylobacterium extorquens DM4 8196227 YP_003066252.1 CDS fbpA NC_012988.1 511965 512990 D Evidence 2b : Function of strongly homologous gene; PubMedId : 16926146; Product type t : transporter; ABC transporter, periplasmic protein precursor, putative iron transporter 511965..512990 Methylobacterium extorquens DM4 8195248 YP_003066253.1 CDS fpbB NC_012988.1 513067 514719 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9884235; Product type t : transporter; ABC transporter, permease precursor, putative iron transporter 513067..514719 Methylobacterium extorquens DM4 8195357 YP_003066254.1 CDS METDI0544 NC_012988.1 514727 514828 R Evidence 6 : Doubtful CDS; hypothetical protein complement(514727..514828) Methylobacterium extorquens DM4 8195440 YP_003066255.1 CDS METDI0545 NC_012988.1 515142 515396 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(515142..515396) Methylobacterium extorquens DM4 8190961 YP_003066256.1 CDS METDI0546 NC_012988.1 515680 516378 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(515680..516378) Methylobacterium extorquens DM4 8190962 YP_003066257.1 CDS METDI0547 NC_012988.1 516565 517530 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 516565..517530 Methylobacterium extorquens DM4 8190963 YP_003066258.1 CDS METDI0548 NC_012988.1 517618 518946 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative flavin containing amine oxidase 517618..518946 Methylobacterium extorquens DM4 8190964 YP_003066259.1 CDS METDI0549 NC_012988.1 519055 519690 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cyclic nucleotide-binding domain 519055..519690 Methylobacterium extorquens DM4 8190965 YP_003066260.1 CDS METDI0550 NC_012988.1 519694 520113 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(519694..520113) Methylobacterium extorquens DM4 8190966 YP_003066261.1 CDS METDI0551 NC_012988.1 520318 520524 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 520318..520524 Methylobacterium extorquens DM4 8190967 YP_003066262.1 CDS METDI0552 NC_012988.1 520684 520797 R Evidence 6 : Doubtful CDS; Product type n : RNA; hypothetical protein complement(520684..520797) Methylobacterium extorquens DM4 8190968 YP_003066263.1 CDS METDI0553 NC_012988.1 520951 521241 R Evidence 6 : Doubtful CDS; hypothetical protein complement(520951..521241) Methylobacterium extorquens DM4 8190969 YP_003066264.1 CDS cysP NC_012988.1 521894 522943 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15188393, 16926146; Product type t : transporter; ABC transporter, periplasmic protein, putative sulfate/thiosulfate transporter 521894..522943 Methylobacterium extorquens DM4 8190970 YP_003066265.1 CDS cysU NC_012988.1 522948 523802 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2188958; Product type t : transporter; ABC transporter, permease, putative sulfate/thiosulfate transporter 522948..523802 Methylobacterium extorquens DM4 8195260 YP_003066266.1 CDS cysW NC_012988.1 523807 524697 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2188958; Product type t : transporter; ABC transporter, permease, putative sulfate/thiosulfate transporter 523807..524697 Methylobacterium extorquens DM4 8195262 YP_003066267.1 CDS cysA NC_012988.1 524702 525745 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2188958; Product type t : transporter; ABC transporter, ATPase, putative sulfate/thiosulfate transporter 524702..525745 Methylobacterium extorquens DM4 8195263 YP_003066268.1 CDS METDI0563 NC_012988.1 532146 532616 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(532146..532616) Methylobacterium extorquens DM4 8196084 YP_003066269.1 CDS nth NC_012988.1 532799 533500 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2669955; Product type e : enzyme; endonuclease III DNA glycosylase/apyrimidinic (AP) lyase 532799..533500 Methylobacterium extorquens DM4 8190971 YP_003066270.1 CDS purC NC_012988.1 533694 534488 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 533694..534488 Methylobacterium extorquens DM4 8195784 YP_003066271.1 CDS METDI0566 NC_012988.1 534496 536151 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(534496..536151) Methylobacterium extorquens DM4 8195931 YP_003066272.1 CDS METDI0567 NC_012988.1 536148 538202 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8626291; Product type pe : putative enzyme; putative glycosyl transferase complement(536148..538202) Methylobacterium extorquens DM4 8190972 YP_003066273.1 CDS METDI0568 NC_012988.1 538261 538851 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(538261..538851) Methylobacterium extorquens DM4 8190973 YP_003066274.1 CDS METDI0569 NC_012988.1 538954 539496 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(538954..539496) Methylobacterium extorquens DM4 8190974 YP_003066275.1 CDS METDI0570 NC_012988.1 539733 540152 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 539733..540152 Methylobacterium extorquens DM4 8190975 YP_003066276.1 CDS METDI0571 NC_012988.1 540239 540964 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal-dependent hydrolase complement(540239..540964) Methylobacterium extorquens DM4 8190976 YP_003066277.1 CDS depA NC_012988.1 541060 542304 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; intracellular PHB depolymerase complement(541060..542304) Methylobacterium extorquens DM4 8190977 YP_003066278.1 CDS regS NC_012988.1 542450 543844 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9683482; Product type e : enzyme; two component sensor histidine kinase, RegS 542450..543844 Methylobacterium extorquens DM4 8195289 YP_003066279.1 CDS regR NC_012988.1 543881 544483 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9683482; Product type r : regulator; two-component transcriptional regulator RegR, Fis family 543881..544483 Methylobacterium extorquens DM4 8195977 YP_003066280.1 CDS METDI0575 NC_012988.1 544665 544889 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 544665..544889 Methylobacterium extorquens DM4 8195976 YP_003066281.1 CDS yexA NC_012988.1 545081 545320 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10784038; Product type pf : putative factor; Phosphoribosylformylglycinamidine synthetase PurS 545081..545320 Methylobacterium extorquens DM4 8190978 YP_003066282.1 CDS purQ NC_012988.1 545320 546000 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 545320..546000 Methylobacterium extorquens DM4 8196363 YP_003066283.1 CDS apt NC_012988.1 546126 546671 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(546126..546671) Methylobacterium extorquens DM4 8195940 YP_003066284.1 CDS suhB NC_012988.1 546754 547548 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10747806, 8002619; Product type e : enzyme; inositol monophosphatase complement(546754..547548) Methylobacterium extorquens DM4 8195077 YP_003066285.1 CDS thiE NC_012988.1 547832 548449 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; thiamine-phosphate pyrophosphorylase (TMP pyrophosphorylase) (TMP-PPase) (thiamine-phosphate synthase) complement(547832..548449) Methylobacterium extorquens DM4 8196175 YP_003066286.1 CDS thiG NC_012988.1 548456 549277 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; thiazole synthase complement(548456..549277) Methylobacterium extorquens DM4 8196187 YP_003066287.1 CDS thiS NC_012988.1 549280 549492 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; thiamin biosynthesis proteinsulfur carrier) ThiS complement(549280..549492) Methylobacterium extorquens DM4 8196189 YP_003066288.1 CDS thiO NC_012988.1 549489 550724 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glycine oxidase complement(549489..550724) Methylobacterium extorquens DM4 8196192 YP_003066289.1 CDS METDI0585 NC_012988.1 551048 552322 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Adenylate/Guanylate cyclase complement(551048..552322) Methylobacterium extorquens DM4 8195038 YP_003066290.1 CDS METDI0586 NC_012988.1 552619 552987 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 552619..552987 Methylobacterium extorquens DM4 8190979 YP_003066291.1 CDS METDI0587 NC_012988.1 553279 554283 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 553279..554283 Methylobacterium extorquens DM4 8190980 YP_003066292.1 CDS METDI0588 NC_012988.1 554292 555635 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7592429; Product type pt : putative transporter; major facilitator superfamily (MFS_1) transporter ( putative tartrate transporter, ttuB) 554292..555635 Methylobacterium extorquens DM4 8190981 YP_003066293.1 CDS rpoD NC_012988.1 555680 557680 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(555680..557680) Methylobacterium extorquens DM4 8190982 YP_003066294.1 CDS dnaG NC_012988.1 557882 559807 R synthesizes RNA primers at the replication forks; DNA primase complement(557882..559807) Methylobacterium extorquens DM4 8196047 YP_003066295.1 CDS gnl NC_012988.1 559942 560928 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Gluconolactonase (D-glucono-delta-lactone lactonohydrolase) 559942..560928 Methylobacterium extorquens DM4 8195306 YP_003066296.1 CDS METDI0592 NC_012988.1 560925 562091 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 560925..562091 Methylobacterium extorquens DM4 8195525 YP_003066297.1 CDS gatB NC_012988.1 562280 562738 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B) complement(562280..562738) Methylobacterium extorquens DM4 8190983 YP_003066298.1 CDS carA NC_012988.1 562928 564178 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; carbamoyl phosphate synthetase, glutamine amidotransferase small subunit 562928..564178 Methylobacterium extorquens DM4 8195469 YP_003066299.1 CDS METDI0595 NC_012988.1 564318 564692 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 564318..564692 Methylobacterium extorquens DM4 8195146 YP_003066300.1 CDS METDI0596 NC_012988.1 564733 567393 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(564733..567393) Methylobacterium extorquens DM4 8190984 YP_003066301.1 CDS flgB NC_012988.1 567551 567940 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; flagellar basal body rod protein FlgB 567551..567940 Methylobacterium extorquens DM4 8190985 YP_003066302.1 CDS flgC NC_012988.1 567937 568353 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgC 567937..568353 Methylobacterium extorquens DM4 8195391 YP_003066303.1 CDS fliE NC_012988.1 568367 568720 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; Flagellar hook-basal body complex protein FliE 568367..568720 Methylobacterium extorquens DM4 8195393 YP_003066304.1 CDS flgG NC_012988.1 568813 569601 D makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgG 568813..569601 Methylobacterium extorquens DM4 8195413 YP_003066305.1 CDS flgA NC_012988.1 569667 570161 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; Flagella basal body p ring formation protein FlgA 569667..570161 Methylobacterium extorquens DM4 8195400 YP_003066306.1 CDS flgI NC_012988.1 570158 571285 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar basal body P-ring protein 570158..571285 Methylobacterium extorquens DM4 8195389 YP_003066307.1 CDS METDI0603 NC_012988.1 571285 571869 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 571285..571869 Methylobacterium extorquens DM4 8195404 YP_003066308.1 CDS flgH NC_012988.1 571869 572576 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; flagellar L-ring protein FlgH 571869..572576 Methylobacterium extorquens DM4 8190986 YP_003066309.1 CDS fliL NC_012988.1 572657 573139 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; Flagellar basal body-associated protein FliL 572657..573139 Methylobacterium extorquens DM4 8195402 YP_003066310.1 CDS fliP NC_012988.1 573136 573918 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagellum; flagellar biosynthesis protein FliP 573136..573918 Methylobacterium extorquens DM4 8195421 YP_003066311.1 CDS fliF NC_012988.1 574424 576103 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 574424..576103 Methylobacterium extorquens DM4 8195427 YP_003066312.1 CDS METDI0609 NC_012988.1 576103 576828 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 576103..576828 Methylobacterium extorquens DM4 8195415 YP_003066313.1 CDS motB NC_012988.1 576830 578254 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; Chemotaxis protein MotB 576830..578254 Methylobacterium extorquens DM4 8190987 YP_003066314.1 CDS motC NC_012988.1 578254 579633 D a periplasmic protein that interacts with and stabilizes MotB; in Rhizobium, interactions between MotB and MotC at the periplasmic surface of the motor control the energy flux or the energy coupling that drives flagellar rotation; chemotaxis protein 578254..579633 Methylobacterium extorquens DM4 8195717 YP_003066315.1 CDS METDI0612 NC_012988.1 579673 581526 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 579673..581526 Methylobacterium extorquens DM4 8195719 YP_003066316.1 CDS METDI0613 NC_012988.1 581480 582148 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 581480..582148 Methylobacterium extorquens DM4 8190988 YP_003066317.1 CDS METDI0615 NC_012988.1 582156 582857 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Two-component response regulator complement(582156..582857) Methylobacterium extorquens DM4 8190989 YP_003066318.1 CDS METDI0616 NC_012988.1 583079 583525 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(583079..583525) Methylobacterium extorquens DM4 8190990 YP_003066319.1 CDS flhB NC_012988.1 583522 584583 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar biosynthesis protein FlhB complement(583522..584583) Methylobacterium extorquens DM4 8190991 YP_003066320.1 CDS fliG NC_012988.1 584627 585706 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; flagellar motor switch protein FliG complement(584627..585706) Methylobacterium extorquens DM4 8195411 YP_003066321.1 CDS fliN NC_012988.1 585729 586055 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; flagellar motor switch protein fliN complement(585729..586055) Methylobacterium extorquens DM4 8195417 YP_003066322.1 CDS METDI0620 NC_012988.1 586256 586528 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 586256..586528 Methylobacterium extorquens DM4 8195425 YP_003066323.1 CDS METDI0621 NC_012988.1 586542 586838 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(586542..586838) Methylobacterium extorquens DM4 8190992 YP_003066324.1 CDS fliM NC_012988.1 586822 587844 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; Flagellar motor switch protein FliM complement(586822..587844) Methylobacterium extorquens DM4 8190993 YP_003066325.1 CDS motA NC_012988.1 587859 588734 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; Chemotaxis protein MotA (Motility protein A) complement(587859..588734) Methylobacterium extorquens DM4 8195423 YP_003066326.1 CDS hslV NC_012988.1 588933 589493 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 588933..589493 Methylobacterium extorquens DM4 8195716 YP_003066327.1 CDS hslU NC_012988.1 589605 590918 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 589605..590918 Methylobacterium extorquens DM4 8195579 YP_003066328.1 CDS METDI0626 NC_012988.1 590921 591811 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8021175, 8930920; Product type pt : putative transporter; putative membrane protein DUF6 precursor, putative threonine and homoserine efflux protein 590921..591811 Methylobacterium extorquens DM4 8195578 YP_003066329.1 CDS METDI0627 NC_012988.1 591845 592906 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Beta-lactamase-like complement(591845..592906) Methylobacterium extorquens DM4 8190994 YP_003066330.1 CDS METDI0628 NC_012988.1 592956 594041 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative rieske 2Fe-2S family protein complement(592956..594041) Methylobacterium extorquens DM4 8190995 YP_003066331.1 CDS METDI0629 NC_012988.1 594406 594912 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(594406..594912) Methylobacterium extorquens DM4 8190996 YP_003066332.1 CDS ffh NC_012988.1 595451 597013 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6357787; Product type f : factor; signal recognition particle protein, GTPase 595451..597013 Methylobacterium extorquens DM4 8190997 YP_003066333.1 CDS METDI0633 NC_012988.1 597010 597357 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12581215; Product type pe : putative enzyme; putative chorismate mutase 597010..597357 Methylobacterium extorquens DM4 8195372 YP_003066334.1 CDS rpsP NC_012988.1 597357 597719 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 597357..597719 Methylobacterium extorquens DM4 8190998 YP_003066335.1 CDS rimM NC_012988.1 597844 598515 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 597844..598515 Methylobacterium extorquens DM4 8196067 YP_003066336.1 CDS METDI0636 NC_012988.1 598523 599317 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(598523..599317) Methylobacterium extorquens DM4 8190999 YP_003066337.1 CDS METDI0637 NC_012988.1 599386 600117 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(599386..600117) Methylobacterium extorquens DM4 8191000 YP_003066338.1 CDS METDI0638 NC_012988.1 600227 600544 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 600227..600544 Methylobacterium extorquens DM4 8191001 YP_003066339.1 CDS trmD NC_012988.1 600654 601376 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; tRNA (guanine)-methyltransferase 600654..601376 Methylobacterium extorquens DM4 8191002 YP_003066340.1 CDS serC1 NC_012988.1 601550 602725 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 601550..602725 Methylobacterium extorquens DM4 8196211 YP_003066341.1 CDS serA2 NC_012988.1 602883 604490 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 602883..604490 Methylobacterium extorquens DM4 8196111 YP_003066342.1 CDS METDI0642 NC_012988.1 604468 604818 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 604468..604818 Methylobacterium extorquens DM4 8196110 YP_003066343.1 CDS METDI0643 NC_012988.1 604961 606058 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative translation initiation factor, aIF-2B alpha subunit (eIF-2B) 604961..606058 Methylobacterium extorquens DM4 8191003 YP_003066344.1 CDS METDI0644 NC_012988.1 606070 606417 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative DNA-binding protein complement(606070..606417) Methylobacterium extorquens DM4 8191004 YP_003066345.1 CDS METDI0645 NC_012988.1 606483 607901 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative multidrug efflux system transporter mdtK complement(606483..607901) Methylobacterium extorquens DM4 8191005 YP_003066346.1 CDS METDI0646 NC_012988.1 607926 609782 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, fused ATPase and permease domains complement(607926..609782) Methylobacterium extorquens DM4 8191006 YP_003066347.1 CDS METDI0647 NC_012988.1 609923 610372 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative rRNA methylase 609923..610372 Methylobacterium extorquens DM4 8191007 YP_003066348.1 CDS METDI0648 NC_012988.1 610666 612300 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp : cell process; putative methyl-accepting chemotaxis sensory transducer 610666..612300 Methylobacterium extorquens DM4 8191008 YP_003066349.1 CDS METDI0649 NC_012988.1 612563 613702 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 612563..613702 Methylobacterium extorquens DM4 8191009 YP_003066350.1 CDS METDI0650 NC_012988.1 613699 614367 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 613699..614367 Methylobacterium extorquens DM4 8191010 YP_003066351.1 CDS METDI0651 NC_012988.1 614404 616110 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative inner membrane protein (yqiK-like) 614404..616110 Methylobacterium extorquens DM4 8191011 YP_003066352.1 CDS METDI0652 NC_012988.1 616302 618488 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent siderophore receptor 616302..618488 Methylobacterium extorquens DM4 8191012 YP_003066353.1 CDS hemF NC_012988.1 618532 619455 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 618532..619455 Methylobacterium extorquens DM4 8191013 YP_003066354.1 CDS METDI0654 NC_012988.1 619503 620624 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Exodeoxyribonuclease V 619503..620624 Methylobacterium extorquens DM4 8195552 YP_003066355.1 CDS METDI0655 NC_012988.1 620788 622065 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(620788..622065) Methylobacterium extorquens DM4 8191014 YP_003066356.1 CDS METDI0656 NC_012988.1 622450 623130 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Two-component response regulator 622450..623130 Methylobacterium extorquens DM4 8191015 YP_003066357.1 CDS METDI0657 NC_012988.1 623238 624635 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11514517, 2921241; Product type s : structure; putative flagellin (flaA-like; flaB-like) complement(623238..624635) Methylobacterium extorquens DM4 8191016 YP_003066358.1 CDS METDI0659 NC_012988.1 625158 625457 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(625158..625457) Methylobacterium extorquens DM4 8191017 YP_003066359.1 CDS METDI0660 NC_012988.1 625660 626229 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 625660..626229 Methylobacterium extorquens DM4 8191018 YP_003066360.1 CDS METDI0661 NC_012988.1 626402 627655 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 626402..627655 Methylobacterium extorquens DM4 8191019 YP_003066361.1 CDS flgF NC_012988.1 627661 628389 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; Flagellar basal-body rod protein flgF 627661..628389 Methylobacterium extorquens DM4 8191020 YP_003066362.1 CDS fliI NC_012988.1 628394 629722 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 628394..629722 Methylobacterium extorquens DM4 8195398 YP_003066363.1 CDS flgE NC_012988.1 629805 631016 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 629805..631016 Methylobacterium extorquens DM4 8195419 YP_003066364.1 CDS flgK NC_012988.1 631095 632558 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 631095..632558 Methylobacterium extorquens DM4 8195396 YP_003066365.1 CDS flgL NC_012988.1 632566 633618 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar hook-associated protein FlgL 632566..633618 Methylobacterium extorquens DM4 8195406 YP_003066366.1 CDS flaF NC_012988.1 633659 634009 D acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis regulatory protein FlaF 633659..634009 Methylobacterium extorquens DM4 8195408 YP_003066367.1 CDS flbT NC_012988.1 634020 634541 D post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis repressor FlbT 634020..634541 Methylobacterium extorquens DM4 8195386 YP_003066368.1 CDS flgD NC_012988.1 634548 634964 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod modification protein 634548..634964 Methylobacterium extorquens DM4 8195388 YP_003066369.1 CDS fliQ NC_012988.1 635031 635297 D FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar biosynthesis protein FliQ 635031..635297 Methylobacterium extorquens DM4 8195395 YP_003066370.1 CDS flhA NC_012988.1 635640 637721 D membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 635640..637721 Methylobacterium extorquens DM4 8191021 YP_003066371.1 CDS fliR NC_012988.1 637718 638488 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium has one thick and several thin flagella; the Bradyrhizobium protein in this cluster are associated with the thin flagella; flagellar biosynthesis protein FliR 637718..638488 Methylobacterium extorquens DM4 8195409 YP_003066372.1 CDS METDI0673 NC_012988.1 638494 638904 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 638494..638904 Methylobacterium extorquens DM4 8195429 YP_003066373.1 CDS METDI0674 NC_012988.1 638980 639450 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 638980..639450 Methylobacterium extorquens DM4 8191022 YP_003066374.1 CDS METDI0675 NC_012988.1 639456 639800 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 639456..639800 Methylobacterium extorquens DM4 8191023 YP_003066375.1 CDS METDI0676 NC_012988.1 639804 640250 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 639804..640250 Methylobacterium extorquens DM4 8191024 YP_003066376.1 CDS METDI0677 NC_012988.1 640346 641239 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dihydrodipicolinate synthase (dapA-like) 640346..641239 Methylobacterium extorquens DM4 8191025 YP_003066377.1 CDS METDI0678 NC_012988.1 641341 642327 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 641341..642327 Methylobacterium extorquens DM4 8191026 YP_003066378.1 CDS METDI0679 NC_012988.1 642343 642684 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(642343..642684) Methylobacterium extorquens DM4 8191027 YP_003066379.1 CDS METDI0680 NC_012988.1 642746 643495 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(642746..643495) Methylobacterium extorquens DM4 8191028 YP_003066380.1 CDS METDI0681 NC_012988.1 643539 645479 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1438215; Product type e : enzyme; Two-component sensor histidine kinase with a PAS domain complement(643539..645479) Methylobacterium extorquens DM4 8191029 YP_003066381.1 CDS METDI0682 NC_012988.1 645858 646190 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 645858..646190 Methylobacterium extorquens DM4 8191030 YP_003066382.1 CDS qxtB NC_012988.1 646342 647385 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11064196; Product type e : enzyme; Cytochrome bd ubiquinol oxidase, subunit II 646342..647385 Methylobacterium extorquens DM4 8191031 YP_003066383.1 CDS METDI0686 NC_012988.1 647616 648845 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Major facilitator superfamily transport protein complement(647616..648845) Methylobacterium extorquens DM4 8195957 YP_003066384.1 CDS METDI0687 NC_012988.1 648926 650143 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Major facilitator superfamily transport protein complement(648926..650143) Methylobacterium extorquens DM4 8191032 YP_003066385.1 CDS METDI0688 NC_012988.1 650250 650702 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, HxlR family 650250..650702 Methylobacterium extorquens DM4 8191033 YP_003066386.1 CDS METDI0689 NC_012988.1 650999 653491 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8335642; Product type e : enzyme; Penicillin-binding protein 1A 650999..653491 Methylobacterium extorquens DM4 8191034 YP_003066387.1 CDS METDI0690 NC_012988.1 653698 655395 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9163424; Product type pr : putative regulator; putative Methyl-accepting chemotaxis protein/ histidine kinase 653698..655395 Methylobacterium extorquens DM4 8191035 YP_003066388.1 CDS amn NC_012988.1 655511 656998 R Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase complement(655511..656998) Methylobacterium extorquens DM4 8191036 YP_003066389.1 CDS METDI0692 NC_012988.1 657180 657686 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 657180..657686 Methylobacterium extorquens DM4 8195072 YP_003066390.1 CDS METDI0693 NC_012988.1 657706 659016 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(657706..659016) Methylobacterium extorquens DM4 8191037 YP_003066391.1 CDS METDI0694 NC_012988.1 659225 660067 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(659225..660067) Methylobacterium extorquens DM4 8191038 YP_003066392.1 CDS METDI0695 NC_012988.1 660539 660970 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(660539..660970) Methylobacterium extorquens DM4 8191039 YP_003066393.1 CDS METDI0696 NC_012988.1 661032 661925 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11259647; Product type e : enzyme; Histone deacetylase family protein complement(661032..661925) Methylobacterium extorquens DM4 8191040 YP_003066394.1 CDS METDI0697 NC_012988.1 662041 663225 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Ceramide glucosyltransferase 662041..663225 Methylobacterium extorquens DM4 8191041 YP_003066395.1 CDS METDI0698 NC_012988.1 663727 665274 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14675535; Product type ps : putative structure; putative crescentin ( creS ) 663727..665274 Methylobacterium extorquens DM4 8191042 YP_003066396.1 CDS METDI0699 NC_012988.1 665331 665822 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 665331..665822 Methylobacterium extorquens DM4 8191043 YP_003066397.1 CDS METDI0700 NC_012988.1 665840 666346 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 665840..666346 Methylobacterium extorquens DM4 8191044 YP_003066398.1 CDS METDI0701 NC_012988.1 666568 667944 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; permease; putative ethanolamine transporter 666568..667944 Methylobacterium extorquens DM4 8191045 YP_003066399.1 CDS METDI0702 NC_012988.1 668149 669081 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative fatty acid desaturase ; putative membrane component complement(668149..669081) Methylobacterium extorquens DM4 8191046 YP_003066400.1 CDS METDI0703 NC_012988.1 669115 669486 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, ArsR family 669115..669486 Methylobacterium extorquens DM4 8191047 YP_003066401.1 CDS METDI0704 NC_012988.1 670101 670793 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glutamine amidotransferase, class-I family protein (guaA-like) 670101..670793 Methylobacterium extorquens DM4 8191048 YP_003066402.1 CDS METDI0705 NC_012988.1 670898 671914 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, aldo/keto reductase family complement(670898..671914) Methylobacterium extorquens DM4 8191049 YP_003066403.1 CDS METDI0706 NC_012988.1 672063 672974 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, AraC family 672063..672974 Methylobacterium extorquens DM4 8191050 YP_003066404.1 CDS METDI0707 NC_012988.1 673123 674445 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative integrase 673123..674445 Methylobacterium extorquens DM4 8191051 YP_003066405.1 CDS METDI0712 NC_012988.1 676038 676352 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 676038..676352 Methylobacterium extorquens DM4 8191055 YP_003066406.1 CDS METDI0713 NC_012988.1 676784 677932 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 676784..677932 Methylobacterium extorquens DM4 8191056 YP_003066407.1 CDS METDI0714 NC_012988.1 677929 678159 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 677929..678159 Methylobacterium extorquens DM4 8191057 YP_003066408.1 CDS METDI0716 NC_012988.1 678468 679220 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) complement(678468..679220) Methylobacterium extorquens DM4 8191059 YP_003066409.1 CDS METDI0717 NC_012988.1 679328 679609 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) complement(679328..679609) Methylobacterium extorquens DM4 8191060 YP_003066410.1 CDS METDI0720 NC_012988.1 680494 680952 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(680494..680952) Methylobacterium extorquens DM4 8191063 YP_003066411.1 CDS METDI0722 NC_012988.1 681019 681360 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, ArsR family 681019..681360 Methylobacterium extorquens DM4 8191064 YP_003066412.1 CDS METDI0723 NC_012988.1 681368 681793 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 681368..681793 Methylobacterium extorquens DM4 8191065 YP_003066413.1 CDS METDI0724 NC_012988.1 681799 682257 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 681799..682257 Methylobacterium extorquens DM4 8191066 YP_003066414.1 CDS METDI0725 NC_012988.1 682254 683063 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 682254..683063 Methylobacterium extorquens DM4 8191067 YP_003066415.1 CDS METDI0726 NC_012988.1 683085 683996 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; beta-lactamase domain protein, putative hydroxyacylglutathione hydrolase 683085..683996 Methylobacterium extorquens DM4 8191068 YP_003066416.1 CDS METDI0727 NC_012988.1 683993 684394 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; rhodanese domain protein, putative sulfur transferase 683993..684394 Methylobacterium extorquens DM4 8191069 YP_003066417.1 CDS METDI0728 NC_012988.1 684751 686067 R Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; integral membrane sensor signal transduction histidine kinase precursor complement(684751..686067) Methylobacterium extorquens DM4 8191070 YP_003066418.1 CDS METDI0729 NC_012988.1 686064 686726 R Evidence 2b : Function of strongly homologous gene; PubMedId : 21927389; Product type r : regulator; DNA-binding response regulator in two-component regulatory system complement(686064..686726) Methylobacterium extorquens DM4 8191071 YP_003066419.1 CDS METDI0730 NC_012988.1 686833 688605 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative fused thiol:disulfide interchange protein precursor 686833..688605 Methylobacterium extorquens DM4 8191072 YP_003066420.1 CDS METDI0731 NC_012988.1 688645 689280 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thioredoxin domain protein precursor 688645..689280 Methylobacterium extorquens DM4 8191073 YP_003066421.1 CDS METDI0732 NC_012988.1 689280 690128 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 689280..690128 Methylobacterium extorquens DM4 8191074 YP_003066422.1 CDS ragC NC_012988.1 691319 694636 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; putative cation efflux system protein 691319..694636 Methylobacterium extorquens DM4 8191075 YP_003066423.1 CDS METDI0737 NC_012988.1 694623 695903 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10675036; Product type t : transporter; Efflux transporter, RND family, membrane fusion protein subunit; RagD-related 694623..695903 Methylobacterium extorquens DM4 8195961 YP_003066424.1 CDS METDI0738 NC_012988.1 696009 696311 R Evidence 6 : Doubtful CDS; hypothetical protein complement(696009..696311) Methylobacterium extorquens DM4 8191076 YP_003066425.1 CDS METDI0739 NC_012988.1 696636 697358 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 696636..697358 Methylobacterium extorquens DM4 8191077 YP_003066426.1 CDS METDI0740 NC_012988.1 697572 697937 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 697572..697937 Methylobacterium extorquens DM4 8191078 YP_003066427.1 CDS METDI0741 NC_012988.1 697957 698760 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative thiol:disulfide interchange protein 697957..698760 Methylobacterium extorquens DM4 8191079 YP_003066428.1 CDS METDI0742 NC_012988.1 698800 699315 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nuclease precursor 698800..699315 Methylobacterium extorquens DM4 8191080 YP_003066429.1 CDS METDI0744 NC_012988.1 699571 699762 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 699571..699762 Methylobacterium extorquens DM4 8191082 YP_003066430.1 CDS METDI0745 NC_012988.1 699832 700047 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 699832..700047 Methylobacterium extorquens DM4 8191083 YP_003066431.1 CDS METDI0747 NC_012988.1 700827 701498 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transglutaminase-like cysteine peptidase precursor complement(700827..701498) Methylobacterium extorquens DM4 8191085 YP_003066432.1 CDS METDI0748 NC_012988.1 701711 702730 R Evidence 2b : Function of strongly homologous gene; PubMedId : 16517654; Product type e : enzyme; transposase of ISMdi4, IS481 family complement(701711..702730) Methylobacterium extorquens DM4 8191086 YP_003066433.1 CDS METDI0749 NC_012988.1 702857 703846 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15665824; Product type e : enzyme; putative sulfate-binding protein complement(702857..703846) Methylobacterium extorquens DM4 8191087 YP_003066434.1 CDS METDI0750 NC_012988.1 703856 704323 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(703856..704323) Methylobacterium extorquens DM4 8191088 YP_003066435.1 CDS METDI0751 NC_012988.1 704393 704854 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(704393..704854) Methylobacterium extorquens DM4 8191089 YP_003066436.1 CDS METDI0752 NC_012988.1 704950 705915 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallo-beta-lactamase family protein complement(704950..705915) Methylobacterium extorquens DM4 8191090 YP_003066437.1 CDS METDI0753 NC_012988.1 705942 706622 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative sulfite oxidase cytochrome subunit (SoxD) complement(705942..706622) Methylobacterium extorquens DM4 8191091 YP_003066438.1 CDS soxC NC_012988.1 706606 707895 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sulfite oxidase precursor (tat pathway signal) complement(706606..707895) Methylobacterium extorquens DM4 8191092 YP_003066439.1 CDS soxB NC_012988.1 707949 709628 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sulfur/thiosulfate oxidation protein precursor (tat pathway signal) complement(707949..709628) Methylobacterium extorquens DM4 8196129 YP_003066440.1 CDS soxA NC_012988.1 709644 710486 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11567011, 12411478; Product type c : carrier; diheme cytochrome c, sulfur oxidising protein SoxA complement(709644..710486) Methylobacterium extorquens DM4 8196126 YP_003066441.1 CDS soxZ NC_012988.1 710674 711003 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11285738, 14645228; Product type e : enzyme; sulfur oxidation protein SoxZ complement(710674..711003) Methylobacterium extorquens DM4 8196123 YP_003066442.1 CDS soxY NC_012988.1 711045 711524 R with SoxZ catalyzes the oxidation of sulfur compounds; sulfur oxidation protein SoxY complement(711045..711524) Methylobacterium extorquens DM4 8196141 YP_003066443.1 CDS soxX NC_012988.1 711521 711997 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11567011, 12411478, 12597275; Product type c : carrier; cytochrome c SoxX precursor complement(711521..711997) Methylobacterium extorquens DM4 8196140 YP_003066444.1 CDS soxW NC_012988.1 712166 712741 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Thioredoxin SoxW protein complement(712166..712741) Methylobacterium extorquens DM4 8196139 YP_003066445.1 CDS METDI0761 NC_012988.1 712772 713560 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 712772..713560 Methylobacterium extorquens DM4 8196138 YP_003066446.1 CDS soxV NC_012988.1 713604 714338 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sulfur oxidation V protein, cytochrome c-type biogenesis protein complement(713604..714338) Methylobacterium extorquens DM4 8191093 YP_003066447.1 CDS soxS NC_012988.1 714435 714779 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10894738, 11567011; Product type e : enzyme; regulatory protein SoxS precursor 714435..714779 Methylobacterium extorquens DM4 8196137 YP_003066448.1 CDS soxR NC_012988.1 714835 715191 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type pr : putative regulator; transcriptional regulator, ArsR family; putative SoxR protein 714835..715191 Methylobacterium extorquens DM4 8196135 YP_003066449.1 CDS METDI0765 NC_012988.1 715285 715785 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(715285..715785) Methylobacterium extorquens DM4 8196134 YP_003066450.1 CDS soxT NC_012988.1 715933 716985 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; SoxT protein, YeeE/YedE family protein complement(715933..716985) Methylobacterium extorquens DM4 8191094 YP_003066451.1 CDS METDI0769 NC_012988.1 717385 717948 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS transporter superfamily protein domain complement(717385..717948) Methylobacterium extorquens DM4 8196136 YP_003066452.1 CDS METDI0771 NC_012988.1 718644 719042 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(718644..719042) Methylobacterium extorquens DM4 8191095 YP_003066453.1 CDS METDI0772 NC_012988.1 719598 720038 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 719598..720038 Methylobacterium extorquens DM4 8191096 YP_003066454.1 CDS METDI0774 NC_012988.1 720498 720725 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 720498..720725 Methylobacterium extorquens DM4 8191098 YP_003066455.1 CDS sucD NC_012988.1 720822 721727 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; succinyl-CoA synthetase, alpha subunit complement(720822..721727) Methylobacterium extorquens DM4 8191099 YP_003066456.1 CDS sucC NC_012988.1 721724 722890 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; succinyl-CoA synthetase, beta subunit complement(721724..722890) Methylobacterium extorquens DM4 8196168 YP_003066457.1 CDS METDI0777 NC_012988.1 722887 724278 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8550525; Product type pe : putative enzyme; putative succinate-semialdehyde dehydrogenase complement(722887..724278) Methylobacterium extorquens DM4 8196166 YP_003066458.1 CDS METDI0778 NC_012988.1 724454 725725 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator superfamily complement(724454..725725) Methylobacterium extorquens DM4 8191100 YP_003066459.1 CDS METDI0779 NC_012988.1 726043 726861 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family 726043..726861 Methylobacterium extorquens DM4 8191101 YP_003066460.1 CDS METDI0780 NC_012988.1 726987 727199 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 726987..727199 Methylobacterium extorquens DM4 8191102 YP_003066461.1 CDS METDI0781 NC_012988.1 727483 729183 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glucose-methanol-choline oxidoreductase 727483..729183 Methylobacterium extorquens DM4 8191103 YP_003066462.1 CDS METDI0782 NC_012988.1 729180 730568 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; MFS transporter membrane protein 729180..730568 Methylobacterium extorquens DM4 8191104 YP_003066463.1 CDS METDI0783 NC_012988.1 730708 731733 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 730708..731733 Methylobacterium extorquens DM4 8191105 YP_003066464.1 CDS sorA NC_012988.1 731790 732995 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788424, 11285738; Product type e : enzyme; Sulfite:cytochrome c oxidoreductase subunit A 731790..732995 Methylobacterium extorquens DM4 8191106 YP_003066465.1 CDS METDI0785 NC_012988.1 733007 733345 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788424; Product type e : enzyme; Sulfite:cytochrome c oxidoreductase subunit B precursor 733007..733345 Methylobacterium extorquens DM4 8196122 YP_003066466.1 CDS METDI0786 NC_012988.1 733379 734722 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfite oxidase (soxC-like) 733379..734722 Methylobacterium extorquens DM4 8191107 YP_003066467.1 CDS METDI0787 NC_012988.1 734685 735251 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; Cytochrome c, class I precursor 734685..735251 Methylobacterium extorquens DM4 8191108 YP_003066468.1 CDS xsc NC_012988.1 735334 737124 R catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source; sulfoacetaldehyde acetyltransferase complement(735334..737124) Methylobacterium extorquens DM4 8191109 YP_003066469.1 CDS METDI0789 NC_012988.1 737319 738095 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2185227; Product type r : regulator; DNA-binding transcriptional repressor, IclR family 737319..738095 Methylobacterium extorquens DM4 8196342 YP_003066470.1 CDS METDI0790 NC_012988.1 738133 739317 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetate kinase (ackA) 738133..739317 Methylobacterium extorquens DM4 8191110 YP_003066471.1 CDS METDI0794 NC_012988.1 740345 741565 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(740345..741565) Methylobacterium extorquens DM4 8191114 YP_003066472.1 CDS METDI0795 NC_012988.1 741438 742184 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(741438..742184) Methylobacterium extorquens DM4 8191115 YP_003066473.1 CDS METDI0796 NC_012988.1 742072 742692 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(742072..742692) Methylobacterium extorquens DM4 8191116 YP_003066474.1 CDS METDI0798 NC_012988.1 743367 743588 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 743367..743588 Methylobacterium extorquens DM4 8191118 YP_003066475.1 CDS METDI0799 NC_012988.1 743625 743960 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, XRE family complement(743625..743960) Methylobacterium extorquens DM4 8191119 YP_003066476.1 CDS METDI0800 NC_012988.1 744099 744314 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(744099..744314) Methylobacterium extorquens DM4 8191120 YP_003066477.1 CDS METDI0801 NC_012988.1 744283 744759 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, XRE family complement(744283..744759) Methylobacterium extorquens DM4 8191121 YP_003066478.1 CDS METDI0804 NC_012988.1 745540 745677 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(745540..745677) Methylobacterium extorquens DM4 8191122 YP_003066479.1 CDS METDI0805 NC_012988.1 745750 745965 R Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein complement(745750..745965) Methylobacterium extorquens DM4 8191123 YP_003066480.1 CDS METDI0806 NC_012988.1 745893 746060 R Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein complement(745893..746060) Methylobacterium extorquens DM4 8191124 YP_003066481.1 CDS METDI0807 NC_012988.1 746343 747782 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(746343..747782) Methylobacterium extorquens DM4 8191125 YP_003066482.1 CDS METDI0808 NC_012988.1 747965 748210 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(747965..748210) Methylobacterium extorquens DM4 8191126 YP_003066483.1 CDS METDI0809 NC_012988.1 748590 748943 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(748590..748943) Methylobacterium extorquens DM4 8191127 YP_003066484.1 CDS METDI0810 NC_012988.1 749765 750043 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(749765..750043) Methylobacterium extorquens DM4 8191128 YP_003066485.1 CDS METDI0811 NC_012988.1 750525 750599 D Evidence 6 : Doubtful CDS; hypothetical protein 750525..750599 Methylobacterium extorquens DM4 8191129 YP_003066486.1 CDS METDI0813 NC_012988.1 751198 751671 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(751198..751671) Methylobacterium extorquens DM4 8191131 YP_003066487.1 CDS METDI0814 NC_012988.1 751638 752219 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(751638..752219) Methylobacterium extorquens DM4 8191132 YP_003066488.1 CDS METDI0815 NC_012988.1 752346 752552 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 752346..752552 Methylobacterium extorquens DM4 8191133 YP_003066489.1 CDS METDI0816 NC_012988.1 752634 752846 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(752634..752846) Methylobacterium extorquens DM4 8191134 YP_003066490.1 CDS METDI0817 NC_012988.1 752863 753267 R Evidence 6 : Doubtful CDS; hypothetical protein complement(752863..753267) Methylobacterium extorquens DM4 8191135 YP_003066491.1 CDS METDI0818 NC_012988.1 753180 753401 R Evidence 6 : Doubtful CDS; hypothetical protein complement(753180..753401) Methylobacterium extorquens DM4 8191136 YP_003066492.1 CDS METDI0819 NC_012988.1 753702 754718 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(753702..754718) Methylobacterium extorquens DM4 8191137 YP_003066493.1 CDS METDI0820 NC_012988.1 755402 755746 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(755402..755746) Methylobacterium extorquens DM4 8191138 YP_003066494.1 CDS METDI0821 NC_012988.1 756093 756329 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(756093..756329) Methylobacterium extorquens DM4 8191139 YP_003066495.1 CDS METDI0822 NC_012988.1 756692 756940 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 756692..756940 Methylobacterium extorquens DM4 8191140 YP_003066496.1 CDS METDI0823 NC_012988.1 757180 757701 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 757180..757701 Methylobacterium extorquens DM4 8191141 YP_003066497.1 CDS METDI0826 NC_012988.1 759596 760822 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Oxidoreductase complement(759596..760822) Methylobacterium extorquens DM4 8196243 YP_003066498.1 CDS METDI0827 NC_012988.1 761033 761614 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7678242; Product type pm : putative membrane component; putative membrane protein, putative DedA family protein 761033..761614 Methylobacterium extorquens DM4 8191145 YP_003066499.1 CDS METDI0828 NC_012988.1 761611 762135 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12562793; Product type pe : putative enzyme; putative DsbB-like disulfide oxidoreductase precursor 761611..762135 Methylobacterium extorquens DM4 8191146 YP_003066500.1 CDS METDI0829 NC_012988.1 762099 762716 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(762099..762716) Methylobacterium extorquens DM4 8191147 YP_003066501.1 CDS METDI0830 NC_012988.1 763098 764288 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Acyltransferase 3 763098..764288 Methylobacterium extorquens DM4 8191148 YP_003066502.1 CDS METDI0831 NC_012988.1 764304 764726 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(764304..764726) Methylobacterium extorquens DM4 8191149 YP_003066503.1 CDS gpsA NC_012988.1 764828 765853 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(764828..765853) Methylobacterium extorquens DM4 8191150 YP_003066504.1 CDS METDI0833 NC_012988.1 766399 767874 D Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; methyl-accepting chemotaxis receptor/sensory transducer 766399..767874 Methylobacterium extorquens DM4 8195530 YP_003066505.1 CDS ygjD NC_012988.1 767891 768934 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(767891..768934) Methylobacterium extorquens DM4 8191151 YP_003066506.1 CDS METDI0835 NC_012988.1 769112 769825 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 90104310; Product type pe : putative enzyme; putative uroporphyrinogen III synthase 769112..769825 Methylobacterium extorquens DM4 8196367 YP_003066507.1 CDS METDI0837 NC_012988.1 769981 772272 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 769981..772272 Methylobacterium extorquens DM4 8191152 YP_003066508.1 CDS METDI0838 NC_012988.1 772390 773925 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 772390..773925 Methylobacterium extorquens DM4 8191153 YP_003066509.1 CDS METDI0840 NC_012988.1 774239 775594 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phage integrase 774239..775594 Methylobacterium extorquens DM4 8196262 YP_003066510.1 CDS METDI0842 NC_012988.1 775756 776652 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; LysR family transcriptional regulator complement(775756..776652) Methylobacterium extorquens DM4 8191156 YP_003066511.1 CDS METDI0843 NC_012988.1 776754 777404 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dinucleotide-binding enzyme oxidoreductase protein precursor 776754..777404 Methylobacterium extorquens DM4 8191157 YP_003066512.1 CDS METDI0844 NC_012988.1 777641 778495 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Zinc-containing alcohol dehydrogenase superfamily 777641..778495 Methylobacterium extorquens DM4 8191158 YP_003066513.1 CDS METDI0845 NC_012988.1 778718 779143 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) 778718..779143 Methylobacterium extorquens DM4 8191159 YP_003066514.1 CDS METDI0846 NC_012988.1 778918 779472 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) 778918..779472 Methylobacterium extorquens DM4 8191160 YP_003066515.1 CDS METDI0849 NC_012988.1 780311 781843 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 780311..781843 Methylobacterium extorquens DM4 8191163 YP_003066516.1 CDS METDI0850 NC_012988.1 782110 782730 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase complement(782110..782730) Methylobacterium extorquens DM4 8191164 YP_003066517.1 CDS METDI0851 NC_012988.1 783114 786200 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL), with GAF and two PAS/PAC sensor domains 783114..786200 Methylobacterium extorquens DM4 8191165 YP_003066518.1 CDS METDI0853 NC_012988.1 788351 789493 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 788351..789493 Methylobacterium extorquens DM4 8191167 YP_003066519.1 CDS METDI0854 NC_012988.1 789493 789840 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 789493..789840 Methylobacterium extorquens DM4 8191168 YP_003066520.1 CDS METDI0855 NC_012988.1 789886 790179 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 789886..790179 Methylobacterium extorquens DM4 8191169 YP_003066521.1 CDS METDI0856 NC_012988.1 790298 791377 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(790298..791377) Methylobacterium extorquens DM4 8191170 YP_003066522.1 CDS METDI0857 NC_012988.1 791390 792253 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(791390..792253) Methylobacterium extorquens DM4 8191171 YP_003066523.1 CDS METDI0858 NC_012988.1 793382 794002 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase 793382..794002 Methylobacterium extorquens DM4 8191172 YP_003066524.1 CDS METDI0859 NC_012988.1 794269 795801 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(794269..795801) Methylobacterium extorquens DM4 8191173 YP_003066525.1 CDS METDI0861 NC_012988.1 796201 796521 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 796201..796521 Methylobacterium extorquens DM4 8191175 YP_003066526.1 CDS METDI0862 NC_012988.1 796518 798377 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase complement(796518..798377) Methylobacterium extorquens DM4 8191176 YP_003066527.1 CDS METDI0863 NC_012988.1 798370 798918 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(798370..798918) Methylobacterium extorquens DM4 8191177 YP_003066528.1 CDS METDI0864 NC_012988.1 798918 799463 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(798918..799463) Methylobacterium extorquens DM4 8191178 YP_003066529.1 CDS METDI0865 NC_012988.1 800026 801039 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi14, IS110 family complement(800026..801039) Methylobacterium extorquens DM4 8191179 YP_003066530.1 CDS METDI0866 NC_012988.1 801508 802749 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Multidrug resistance efflux pump complement(801508..802749) Methylobacterium extorquens DM4 8191180 YP_003066531.1 CDS METDI0867 NC_012988.1 802746 803207 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(802746..803207) Methylobacterium extorquens DM4 8191181 YP_003066532.1 CDS METDI0868 NC_012988.1 803483 803908 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) 803483..803908 Methylobacterium extorquens DM4 8191182 YP_003066533.1 CDS METDI0873 NC_012988.1 806283 806447 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(806283..806447) Methylobacterium extorquens DM4 8191187 YP_003066534.1 CDS METDI0874 NC_012988.1 806343 807155 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family 806343..807155 Methylobacterium extorquens DM4 8191188 YP_003066535.1 CDS METDI0875 NC_012988.1 807269 807676 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver complement(807269..807676) Methylobacterium extorquens DM4 8191189 YP_003066536.1 CDS METDI0876 NC_012988.1 807902 808117 R Evidence 6 : Doubtful CDS; hypothetical protein complement(807902..808117) Methylobacterium extorquens DM4 8191190 YP_003066537.1 CDS METDI0877 NC_012988.1 808397 808687 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 808397..808687 Methylobacterium extorquens DM4 8191191 YP_003066538.1 CDS METDI0878 NC_012988.1 808943 809320 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dioxygenase complement(808943..809320) Methylobacterium extorquens DM4 8191192 YP_003066539.1 CDS METDI0879 NC_012988.1 809597 809818 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(809597..809818) Methylobacterium extorquens DM4 8191193 YP_003066540.1 CDS METDI0880 NC_012988.1 810013 810390 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 810013..810390 Methylobacterium extorquens DM4 8191194 YP_003066541.1 CDS METDI0881 NC_012988.1 810458 811858 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative monooxygenase, Cytochrome P450 810458..811858 Methylobacterium extorquens DM4 8191195 YP_003066542.1 CDS METDI0883 NC_012988.1 812548 813168 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12207015; Product type pe : putative enzyme; putative 5-formyltetrahydrofolate cyclo-ligase complement(812548..813168) Methylobacterium extorquens DM4 8191197 YP_003066543.1 CDS METDI0884 NC_012988.1 813247 813477 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(813247..813477) Methylobacterium extorquens DM4 8191198 YP_003066544.1 CDS METDI0887 NC_012988.1 814511 814693 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(814511..814693) Methylobacterium extorquens DM4 8191201 YP_003066545.1 CDS METDI0888 NC_012988.1 815198 815455 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(815198..815455) Methylobacterium extorquens DM4 8191202 YP_003066546.1 CDS METDI0889 NC_012988.1 815826 816098 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(815826..816098) Methylobacterium extorquens DM4 8191203 YP_003066547.1 CDS METDI0891 NC_012988.1 817220 817456 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(817220..817456) Methylobacterium extorquens DM4 8191204 YP_003066548.1 CDS METDI0892 NC_012988.1 817453 818583 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator (Crp/Fnr family) with fused CheY-like response receiver and cyclic nucleotide binding domains complement(817453..818583) Methylobacterium extorquens DM4 8191205 YP_003066549.1 CDS METDI0893 NC_012988.1 818853 819566 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family, with N-terminal cNMP-binding domain 818853..819566 Methylobacterium extorquens DM4 8191206 YP_003066550.1 CDS METDI0894 NC_012988.1 819566 819826 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 819566..819826 Methylobacterium extorquens DM4 8191207 YP_003066551.1 CDS METDI0895 NC_012988.1 819874 820179 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 819874..820179 Methylobacterium extorquens DM4 8191208 YP_003066552.1 CDS METDI0896 NC_012988.1 820222 820455 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(820222..820455) Methylobacterium extorquens DM4 8191209 YP_003066553.1 CDS METDI0897 NC_012988.1 820768 821478 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family, with N-terminal cNMP-binding domain 820768..821478 Methylobacterium extorquens DM4 8191210 YP_003066554.1 CDS METDI0898 NC_012988.1 821475 821639 D Evidence 6 : Doubtful CDS; hypothetical protein 821475..821639 Methylobacterium extorquens DM4 8191211 YP_003066555.1 CDS METDI0899 NC_012988.1 822134 822856 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family, with N-terminal cNMP-binding domain 822134..822856 Methylobacterium extorquens DM4 8191212 YP_003066556.1 CDS METDI0900 NC_012988.1 822944 823180 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 822944..823180 Methylobacterium extorquens DM4 8191213 YP_003066557.1 CDS METDI0901 NC_012988.1 823210 823392 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(823210..823392) Methylobacterium extorquens DM4 8191214 YP_003066558.1 CDS METDI0902 NC_012988.1 823391 824020 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA integration/recombination/inversion protein, site-specific recombinase, phage integrase family 823391..824020 Methylobacterium extorquens DM4 8191215 YP_003066559.1 CDS METDI0903 NC_012988.1 824567 825550 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Sulfatase-modifying factor like (SUMF1-related); putative C-alpha-formyglycine-generating enzyme or methyltransferase or protein kinase 824567..825550 Methylobacterium extorquens DM4 8191216 YP_003066560.1 CDS METDI0904 NC_012988.1 825547 826230 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Component of arylsulfatase A-related enzymes 825547..826230 Methylobacterium extorquens DM4 8191217 YP_003066561.1 CDS METDI0905 NC_012988.1 826065 827255 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Component of arylsulfatase A-related enzyme 826065..827255 Methylobacterium extorquens DM4 8191218 YP_003066562.1 CDS METDI0909 NC_012988.1 828530 828700 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 828530..828700 Methylobacterium extorquens DM4 8191222 YP_003066563.1 CDS METDI0910 NC_012988.1 828845 829006 D Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein 828845..829006 Methylobacterium extorquens DM4 8191223 YP_003066564.1 CDS METDI0911 NC_012988.1 829028 829156 D Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein 829028..829156 Methylobacterium extorquens DM4 8191224 YP_003066565.1 CDS METDI0912 NC_012988.1 829296 829508 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 829296..829508 Methylobacterium extorquens DM4 8191225 YP_003066566.1 CDS METDI0914 NC_012988.1 829812 831701 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase of the HWE family 829812..831701 Methylobacterium extorquens DM4 8191226 YP_003066567.1 CDS METDI0915 NC_012988.1 831830 832060 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 831830..832060 Methylobacterium extorquens DM4 8191227 YP_003066568.1 CDS METDI0918 NC_012988.1 832770 833717 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Zinc-containing alcohol dehydrogenase superfamily complement(832770..833717) Methylobacterium extorquens DM4 8191228 YP_003066569.1 CDS METDI0919 NC_012988.1 833864 834748 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8843437; Product type pr : putative regulator; putative transcriptional regulator, LysR family 833864..834748 Methylobacterium extorquens DM4 8191229 YP_003066570.1 CDS METDI0920 NC_012988.1 834749 834979 D Evidence 6 : Doubtful CDS; hypothetical protein 834749..834979 Methylobacterium extorquens DM4 8191230 YP_003066571.1 CDS METDI0924 NC_012988.1 836222 839419 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sensor hybrid histidine kinase with multiple PAS/PAC and response regulator receiver domains complement(836222..839419) Methylobacterium extorquens DM4 8191234 YP_003066572.1 CDS METDI0925 NC_012988.1 839688 840242 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) complement(839688..840242) Methylobacterium extorquens DM4 8191235 YP_003066573.1 CDS METDI0926 NC_012988.1 840017 840442 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) complement(840017..840442) Methylobacterium extorquens DM4 8191236 YP_003066574.1 CDS METDI0927 NC_012988.1 841897 842826 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi4, IS481 family 841897..842826 Methylobacterium extorquens DM4 8191237 YP_003066575.1 CDS METDI0928 NC_012988.1 842839 843006 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(842839..843006) Methylobacterium extorquens DM4 8191238 YP_003066576.1 CDS METDI0930 NC_012988.1 843399 844304 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14704707; Product type e : enzyme; putative Coenzyme B12-binding complement(843399..844304) Methylobacterium extorquens DM4 8191240 YP_003066577.1 CDS METDI0931 NC_012988.1 844482 844655 R Evidence 6 : Doubtful CDS; hypothetical protein complement(844482..844655) Methylobacterium extorquens DM4 8191241 YP_003066578.1 CDS METDI0932 NC_012988.1 844735 845010 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 844735..845010 Methylobacterium extorquens DM4 8191242 YP_003066579.1 CDS METDI0933 NC_012988.1 845213 846670 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phage uncharacterized protein complement(845213..846670) Methylobacterium extorquens DM4 8191243 YP_003066580.1 CDS METDI0934 NC_012988.1 846682 847236 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(846682..847236) Methylobacterium extorquens DM4 8191244 YP_003066581.1 CDS METDI0935 NC_012988.1 847229 848713 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phage methyltransferase complement(847229..848713) Methylobacterium extorquens DM4 8191245 YP_003066582.1 CDS METDI0936 NC_012988.1 849607 849888 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 849607..849888 Methylobacterium extorquens DM4 8191246 YP_003066583.1 CDS METDI0937 NC_012988.1 849919 850149 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(849919..850149) Methylobacterium extorquens DM4 8191247 YP_003066584.1 CDS METDI0938 NC_012988.1 850808 852772 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9163424; Product type prc : putative receptor; putative chemoreceptor y4sI (Methyl-accepting chemotaxis protein) 850808..852772 Methylobacterium extorquens DM4 8191248 YP_003066585.1 CDS METDI0939 NC_012988.1 852896 853546 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 852896..853546 Methylobacterium extorquens DM4 8191249 YP_003066586.1 CDS METDI0940 NC_012988.1 853901 854092 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(853901..854092) Methylobacterium extorquens DM4 8191250 YP_003066587.1 CDS METDI0941 NC_012988.1 854266 854466 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 854266..854466 Methylobacterium extorquens DM4 8191251 YP_003066588.1 CDS METDI0942 NC_012988.1 854618 856762 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 854618..856762 Methylobacterium extorquens DM4 8191252 YP_003066589.1 CDS METDI0948 NC_012988.1 863237 863554 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 863237..863554 Methylobacterium extorquens DM4 8196085 YP_003066590.1 CDS METDI0949 NC_012988.1 863804 866119 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8755871; Product type f : factor; transcriptional accessory protein 863804..866119 Methylobacterium extorquens DM4 8191254 YP_003066591.1 CDS METDI0950 NC_012988.1 866106 866426 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(866106..866426) Methylobacterium extorquens DM4 8191255 YP_003066592.1 CDS METDI0951 NC_012988.1 866974 867627 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ATP-binding protein 866974..867627 Methylobacterium extorquens DM4 8191256 YP_003066593.1 CDS METDI0952 NC_012988.1 867777 869021 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative Capsule polysaccharide export inner-membrane protein 867777..869021 Methylobacterium extorquens DM4 8191257 YP_003066594.1 CDS METDI0953 NC_012988.1 869030 869746 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(869030..869746) Methylobacterium extorquens DM4 8191258 YP_003066595.1 CDS METDI0954 NC_012988.1 869783 870091 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(869783..870091) Methylobacterium extorquens DM4 8191259 YP_003066596.1 CDS flhA NC_012988.1 870292 872433 D membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 870292..872433 Methylobacterium extorquens DM4 8191260 YP_003066597.1 CDS METDI0956 NC_012988.1 872689 874365 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyl-accepting chemotaxis receptor/sensory transducer 872689..874365 Methylobacterium extorquens DM4 8195410 YP_003066598.1 CDS METDI0957 NC_012988.1 874516 874656 R Evidence 6 : Doubtful CDS; hypothetical protein complement(874516..874656) Methylobacterium extorquens DM4 8191261 YP_003066599.1 CDS METDI0958 NC_012988.1 874889 875941 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(874889..875941) Methylobacterium extorquens DM4 8191262 YP_003066600.1 CDS METDI0959 NC_012988.1 876298 876702 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(876298..876702) Methylobacterium extorquens DM4 8191263 YP_003066601.1 CDS fliI NC_012988.1 876798 878153 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(876798..878153) Methylobacterium extorquens DM4 8191264 YP_003066602.1 CDS ctrA NC_012988.1 878592 879293 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11259647, 8548829, 9465034; Product type r : regulator; Cell cycle transcriptional regulator ctrA (Response regulator sokA) 878592..879293 Methylobacterium extorquens DM4 8195420 YP_003066603.1 CDS METDI0962 NC_012988.1 879405 879908 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(879405..879908) Methylobacterium extorquens DM4 8195227 YP_003066604.1 CDS METDI0963 NC_012988.1 880001 880252 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(880001..880252) Methylobacterium extorquens DM4 8191265 YP_003066605.1 CDS METDI0964 NC_012988.1 880286 880960 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8540711; Product type pe : putative enzyme; putative acetyltransferase complement(880286..880960) Methylobacterium extorquens DM4 8191266 YP_003066606.1 CDS dme NC_012988.1 880988 883321 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 880988..883321 Methylobacterium extorquens DM4 8191267 YP_003066607.1 CDS METDI0966 NC_012988.1 883424 884863 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12694921; hypothetical protein 883424..884863 Methylobacterium extorquens DM4 8195299 YP_003066608.1 CDS METDI0967 NC_012988.1 885035 885214 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(885035..885214) Methylobacterium extorquens DM4 8191268 YP_003066609.1 CDS METDI0968 NC_012988.1 885293 886177 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(885293..886177) Methylobacterium extorquens DM4 8191269 YP_003066610.1 CDS METDI0969 NC_012988.1 886174 888249 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase complement(886174..888249) Methylobacterium extorquens DM4 8191270 YP_003066611.1 CDS METDI0970 NC_012988.1 888253 890277 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(888253..890277) Methylobacterium extorquens DM4 8191271 YP_003066612.1 CDS METDI0971 NC_012988.1 890274 890963 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(890274..890963) Methylobacterium extorquens DM4 8191272 YP_003066613.1 CDS METDI0972 NC_012988.1 891159 892544 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; hypothetical protein complement(891159..892544) Methylobacterium extorquens DM4 8191273 YP_003066614.1 CDS METDI0973 NC_012988.1 892833 893357 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, 2Fe-2S subunit 892833..893357 Methylobacterium extorquens DM4 8191274 YP_003066615.1 CDS METDI0974 NC_012988.1 893354 894370 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, FAD-binding subunit; putative molybdopterin oxidoreductase, xanthine dehydrogenase family 893354..894370 Methylobacterium extorquens DM4 8191275 YP_003066616.1 CDS METDI0975 NC_012988.1 894380 896641 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, molybdopterin-binding subunit 894380..896641 Methylobacterium extorquens DM4 8191276 YP_003066617.1 CDS METDI0976 NC_012988.1 896918 897286 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11545279; Product type m : membrane component; integral membrane protein precursor; putative CrcB protein 896918..897286 Methylobacterium extorquens DM4 8191277 YP_003066618.1 CDS METDI0977 NC_012988.1 897283 897735 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 897283..897735 Methylobacterium extorquens DM4 8191278 YP_003066619.1 CDS METDI0978 NC_012988.1 897735 898397 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9687406, 9736537; Product type e : enzyme; D-alanyl-D-alanine dipeptidase 897735..898397 Methylobacterium extorquens DM4 8191279 YP_003066620.1 CDS METDI0979 NC_012988.1 898566 898841 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 898566..898841 Methylobacterium extorquens DM4 8191280 YP_003066621.1 CDS METDI0980 NC_012988.1 898838 899164 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 898838..899164 Methylobacterium extorquens DM4 8191281 YP_003066622.1 CDS METDI0981 NC_012988.1 899282 899923 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, MarR family complement(899282..899923) Methylobacterium extorquens DM4 8191282 YP_003066623.1 CDS METDI0982 NC_012988.1 900170 902347 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase 900170..902347 Methylobacterium extorquens DM4 8191283 YP_003066624.1 CDS rfbF NC_012988.1 902379 903146 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; alpha-D-glucose-1-phosphate cytidylyltransferase 902379..903146 Methylobacterium extorquens DM4 8191284 YP_003066625.1 CDS rfbG NC_012988.1 903146 904252 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; cdp-glucose 4,6-dehydratase 903146..904252 Methylobacterium extorquens DM4 8195985 YP_003066626.1 CDS METDI0985 NC_012988.1 904249 905478 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative Methyltransferase 904249..905478 Methylobacterium extorquens DM4 8195986 YP_003066627.1 CDS rfbC NC_012988.1 905663 906196 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1710759; Product type e : enzyme; dTDP-4-dehydrorhamnose 3,5-epimerase 905663..906196 Methylobacterium extorquens DM4 8191285 YP_003066628.1 CDS METDI0987 NC_012988.1 906193 907233 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative CDP-4-dehydro-6-deoxy-D-gulose 4-reductase 906193..907233 Methylobacterium extorquens DM4 8195982 YP_003066629.1 CDS METDI0988 NC_012988.1 907208 907606 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver complement(907208..907606) Methylobacterium extorquens DM4 8191286 YP_003066630.1 CDS bioA NC_012988.1 907858 909108 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 7,8-diaminopelargonic acid synthetase, PLP-dependent (Adenosylmethionine-8-amino-7-oxononanoate aminotransferase) complement(907858..909108) Methylobacterium extorquens DM4 8191287 YP_003066631.1 CDS gcvP NC_012988.1 909305 912151 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(909305..912151) Methylobacterium extorquens DM4 8195141 YP_003066632.1 CDS gcvH NC_012988.1 912325 912687 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(912325..912687) Methylobacterium extorquens DM4 8195476 YP_003066633.1 CDS gcvT NC_012988.1 912714 913901 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent complement(912714..913901) Methylobacterium extorquens DM4 8195475 YP_003066634.1 CDS METDI0993 NC_012988.1 914210 914440 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(914210..914440) Methylobacterium extorquens DM4 8195040 YP_003066635.1 CDS bioF NC_012988.1 914547 915698 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 7-keto-8-aminopelargonic acid synthetase (8-amino-7-oxononanoate synthase 914547..915698 Methylobacterium extorquens DM4 8191288 YP_003066636.1 CDS METDI0995 NC_012988.1 915705 916565 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(915705..916565) Methylobacterium extorquens DM4 8195145 YP_003066637.1 CDS METDI0997 NC_012988.1 916943 917248 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 916943..917248 Methylobacterium extorquens DM4 8191289 YP_003066638.1 CDS METDI0998 NC_012988.1 917308 917994 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(917308..917994) Methylobacterium extorquens DM4 8191290 YP_003066639.1 CDS METDI0999 NC_012988.1 918057 918773 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MgtC-magnesium transport complement(918057..918773) Methylobacterium extorquens DM4 8191291 YP_003066640.1 CDS METDI1000 NC_012988.1 919065 920057 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8997703; Product type pe : putative enzyme; putative ATPase, MoxR-like protein 919065..920057 Methylobacterium extorquens DM4 8191292 YP_003066641.1 CDS METDI1001 NC_012988.1 920063 920992 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 920063..920992 Methylobacterium extorquens DM4 8191293 YP_003066642.1 CDS METDI1002 NC_012988.1 921161 921622 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 921161..921622 Methylobacterium extorquens DM4 8191294 YP_003066643.1 CDS METDI1003 NC_012988.1 921628 922647 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 921628..922647 Methylobacterium extorquens DM4 8191295 YP_003066644.1 CDS METDI1004 NC_012988.1 922659 923582 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 922659..923582 Methylobacterium extorquens DM4 8191296 YP_003066645.1 CDS METDI1005 NC_012988.1 923582 924520 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 923582..924520 Methylobacterium extorquens DM4 8191297 YP_003066646.1 CDS METDI1006 NC_012988.1 924520 925836 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 924520..925836 Methylobacterium extorquens DM4 8191298 YP_003066647.1 CDS METDI1007 NC_012988.1 925924 927018 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16926146; hypothetical protein 925924..927018 Methylobacterium extorquens DM4 8191299 YP_003066648.1 CDS METDI1008 NC_012988.1 927170 928111 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 927170..928111 Methylobacterium extorquens DM4 8191300 YP_003066649.1 CDS METDI1009 NC_012988.1 928077 928556 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 928077..928556 Methylobacterium extorquens DM4 8191301 YP_003066650.1 CDS METDI1010 NC_012988.1 928122 928412 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(928122..928412) Methylobacterium extorquens DM4 8191302 YP_003066651.1 CDS METDI1011 NC_012988.1 928681 929736 R Evidence 6 : Doubtful CDS; hypothetical protein complement(928681..929736) Methylobacterium extorquens DM4 8191303 YP_003066652.1 CDS msrB NC_012988.1 929982 930398 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; methionine sulfoxide reductase (Peptide-methionine (R)-S-oxide reductase) complement(929982..930398) Methylobacterium extorquens DM4 8191304 YP_003066653.1 CDS rbn2 NC_012988.1 930502 931668 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Ribonuclease BN complement(930502..931668) Methylobacterium extorquens DM4 8195729 YP_003066654.1 CDS METDI1014 NC_012988.1 931801 933267 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sensory transduction histidine kinase complement(931801..933267) Methylobacterium extorquens DM4 8195966 YP_003066655.1 CDS matB NC_012988.1 933471 935003 R catalyzes the formation of malonyl-CoA from malonate and CoA; malonyl-CoA synthase complement(933471..935003) Methylobacterium extorquens DM4 8191305 YP_003066656.1 CDS METDI1016 NC_012988.1 935147 935587 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(935147..935587) Methylobacterium extorquens DM4 8195663 YP_003066657.1 CDS METDI1017 NC_012988.1 935941 936834 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 935941..936834 Methylobacterium extorquens DM4 8191306 YP_003066658.1 CDS METDI1018 NC_012988.1 936847 938070 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(936847..938070) Methylobacterium extorquens DM4 8191307 YP_003066659.1 CDS METDI1019 NC_012988.1 938385 939410 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 938385..939410 Methylobacterium extorquens DM4 8191308 YP_003066660.1 CDS METDI1020 NC_012988.1 939552 939854 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 939552..939854 Methylobacterium extorquens DM4 8191309 YP_003066661.1 CDS pfpI NC_012988.1 939931 940509 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16926146, 17933887, 8626329; Product type e : enzyme; General stress protein, putative intracellular proteinase complement(939931..940509) Methylobacterium extorquens DM4 8191310 YP_003066662.1 CDS METDI1022 NC_012988.1 940693 940914 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 940693..940914 Methylobacterium extorquens DM4 8195848 YP_003066663.1 CDS METDI1024 NC_012988.1 941090 941524 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 941090..941524 Methylobacterium extorquens DM4 8191311 YP_003066664.1 CDS METDI1025 NC_012988.1 941583 941972 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(941583..941972) Methylobacterium extorquens DM4 8191312 YP_003066665.1 CDS cspA NC_012988.1 942318 942527 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; major cold shock protein 942318..942527 Methylobacterium extorquens DM4 8191313 YP_003066666.1 CDS METDI1027 NC_012988.1 942735 942962 D Evidence 6 : Doubtful CDS; hypothetical protein 942735..942962 Methylobacterium extorquens DM4 8195222 YP_003066667.1 CDS METDI1028 NC_012988.1 943132 943572 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(943132..943572) Methylobacterium extorquens DM4 8191314 YP_003066668.1 CDS METDI1029 NC_012988.1 943676 944875 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(943676..944875) Methylobacterium extorquens DM4 8191315 YP_003066669.1 CDS METDI1030 NC_012988.1 945044 946249 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator superfamily 945044..946249 Methylobacterium extorquens DM4 8191316 YP_003066670.1 CDS METDI1031 NC_012988.1 946433 947581 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17369300; Product type pt : putative transporter; putative ABC transporter, permease 946433..947581 Methylobacterium extorquens DM4 8191317 YP_003066671.1 CDS METDI1032 NC_012988.1 947678 948451 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATPase 947678..948451 Methylobacterium extorquens DM4 8191318 YP_003066672.1 CDS METDI1033 NC_012988.1 948523 949605 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein 948523..949605 Methylobacterium extorquens DM4 8191319 YP_003066673.1 CDS METDI1034 NC_012988.1 949726 950349 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative uncharacterized ABC-transporter auxiliary component 949726..950349 Methylobacterium extorquens DM4 8191320 YP_003066674.1 CDS METDI1035 NC_012988.1 950401 951219 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10747806, 8002619; Product type pe : putative enzyme; putative inositol monophosphatase (suhB-like) complement(950401..951219) Methylobacterium extorquens DM4 8191321 YP_003066675.1 CDS METDI1037 NC_012988.1 951585 952085 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 951585..952085 Methylobacterium extorquens DM4 8191322 YP_003066676.1 CDS METDI1038 NC_012988.1 952206 952394 R Evidence 6 : Doubtful CDS; hypothetical protein complement(952206..952394) Methylobacterium extorquens DM4 8191323 YP_003066677.1 CDS ubiA NC_012988.1 952438 953388 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; p-hydroxybenzoate octaprenyltransferase complement(952438..953388) Methylobacterium extorquens DM4 8191324 YP_003066678.1 CDS METDI1040 NC_012988.1 953424 954026 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(953424..954026) Methylobacterium extorquens DM4 8196293 YP_003066679.1 CDS METDI1041 NC_012988.1 954334 955086 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 954334..955086 Methylobacterium extorquens DM4 8191325 YP_003066680.1 CDS METDI1042 NC_012988.1 955116 956099 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative L-asparaginase (ansA-like) 955116..956099 Methylobacterium extorquens DM4 8191326 YP_003066681.1 CDS gshA NC_012988.1 956286 957656 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9807829; Product type e : enzyme; gamma-glutamylcysteine synthetase 956286..957656 Methylobacterium extorquens DM4 8191327 YP_003066682.1 CDS METDI1044 NC_012988.1 957768 958178 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 957768..958178 Methylobacterium extorquens DM4 8195537 YP_003066683.1 CDS METDI1045 NC_012988.1 958258 958524 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfurtransferase tusA 958258..958524 Methylobacterium extorquens DM4 8191328 YP_003066684.1 CDS METDI1046 NC_012988.1 958564 959130 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NUDIX hydrolase 958564..959130 Methylobacterium extorquens DM4 8191329 YP_003066685.1 CDS METDI1047 NC_012988.1 959587 959985 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 959587..959985 Methylobacterium extorquens DM4 8191330 YP_003066686.1 CDS METDI1048 NC_012988.1 960135 960575 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(960135..960575) Methylobacterium extorquens DM4 8191331 YP_003066687.1 CDS METDI1050 NC_012988.1 960821 961522 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(960821..961522) Methylobacterium extorquens DM4 8191332 YP_003066688.1 CDS METDI1051 NC_012988.1 961510 961722 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(961510..961722) Methylobacterium extorquens DM4 8191333 YP_003066689.1 CDS METDI1052 NC_012988.1 961777 962454 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(961777..962454) Methylobacterium extorquens DM4 8191334 YP_003066690.1 CDS cobS NC_012988.1 962469 963296 R Evidence 2b : Function of strongly homologous gene; PubMedId : 96062218; Product type e : enzyme; Cobalamin synthase complement(962469..963296) Methylobacterium extorquens DM4 8191335 YP_003066691.1 CDS cobT NC_012988.1 963464 964501 D Evidence 2b : Function of strongly homologous gene; PubMedId : 96062218; Product type e : enzyme; Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) (N(1)-alpha-phosphoribosyltransferase) 963464..964501 Methylobacterium extorquens DM4 8195196 YP_003066692.1 CDS METDI1055 NC_012988.1 964555 966096 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative integral membrane sensor signal transduction histidine kinase complement(964555..966096) Methylobacterium extorquens DM4 8195198 YP_003066693.1 CDS METDI1056 NC_012988.1 966439 966894 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative aldehyde oxidase, xanthine dehydrogenase family, Fe-S subunit 966439..966894 Methylobacterium extorquens DM4 8191336 YP_003066694.1 CDS METDI1057 NC_012988.1 966891 969125 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldehyde dehydrogenase precursor (tat pathway signal) 966891..969125 Methylobacterium extorquens DM4 8191337 YP_003066695.1 CDS METDI1058 NC_012988.1 969305 972703 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensory histidine kinase, putative methyltransferase, putative sensory_box: PAS domain S-box domain 969305..972703 Methylobacterium extorquens DM4 8191338 YP_003066696.1 CDS METDI1059 NC_012988.1 972791 974032 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275; Product type e : enzyme; Amidase complement(972791..974032) Methylobacterium extorquens DM4 8191339 YP_003066697.1 CDS METDI1060 NC_012988.1 974140 975129 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 974140..975129 Methylobacterium extorquens DM4 8191340 YP_003066698.1 CDS METDI1061 NC_012988.1 975310 975777 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 975310..975777 Methylobacterium extorquens DM4 8191341 YP_003066699.1 CDS METDI1062 NC_012988.1 975877 976551 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2253883, 8188249, 90151658, 90264307; Product type e : enzyme; Ribonuclease T2 975877..976551 Methylobacterium extorquens DM4 8191342 YP_003066700.1 CDS METDI1063 NC_012988.1 977029 977835 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA (exogenous) processing protein, yhiR 977029..977835 Methylobacterium extorquens DM4 8191343 YP_003066701.1 CDS METDI1064 NC_012988.1 977852 978121 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(977852..978121) Methylobacterium extorquens DM4 8191344 YP_003066702.1 CDS METDI1065 NC_012988.1 978136 978366 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(978136..978366) Methylobacterium extorquens DM4 8191345 YP_003066703.1 CDS METDI1066 NC_012988.1 978472 979905 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96178972; Product type pe : putative enzyme; putative glycolate oxidase (glcD-like), FAD-linked subunit complement(978472..979905) Methylobacterium extorquens DM4 8191346 YP_003066704.1 CDS cycA NC_012988.1 980220 980582 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 221822; Product type c : carrier; Cytochrome c2 precursor 980220..980582 Methylobacterium extorquens DM4 8191347 YP_003066705.1 CDS METDI1068 NC_012988.1 980679 981164 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, MarR family complement(980679..981164) Methylobacterium extorquens DM4 8195234 YP_003066706.1 CDS METDI1069 NC_012988.1 981710 982315 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(981710..982315) Methylobacterium extorquens DM4 8191348 YP_003066707.1 CDS METDI1070 NC_012988.1 982315 983055 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(982315..983055) Methylobacterium extorquens DM4 8191349 YP_003066708.1 CDS METDI1071 NC_012988.1 983066 985363 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14704707; Product type pe : putative enzyme; putative penicillin-binding protein complement(983066..985363) Methylobacterium extorquens DM4 8191350 YP_003066709.1 CDS METDI1072 NC_012988.1 985674 986138 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 985674..986138 Methylobacterium extorquens DM4 8191351 YP_003066710.1 CDS METDI1073 NC_012988.1 986148 986804 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(986148..986804) Methylobacterium extorquens DM4 8191352 YP_003066711.1 CDS METDI1074 NC_012988.1 987123 987632 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 987123..987632 Methylobacterium extorquens DM4 8191353 YP_003066712.1 CDS METDI1075 NC_012988.1 987632 988465 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 987632..988465 Methylobacterium extorquens DM4 8191354 YP_003066713.1 CDS METDI1076 NC_012988.1 988462 989883 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 988462..989883 Methylobacterium extorquens DM4 8191355 YP_003066714.1 CDS METDI1078 NC_012988.1 990190 991404 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; AFG1-like ATPase 990190..991404 Methylobacterium extorquens DM4 8191356 YP_003066715.1 CDS METDI1079 NC_012988.1 991401 992027 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11481431; Product type pe : putative enzyme; putative 3-methyladenine DNA glycosylase complement(991401..992027) Methylobacterium extorquens DM4 8191357 YP_003066716.1 CDS rnhA NC_012988.1 992100 992777 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1311386, 1646006, 1698262, 2169648, 2171503, 91120714, 91326034, 94051590; Product type e : enzyme; Ribonuclease H (RNase H) complement(992100..992777) Methylobacterium extorquens DM4 8191358 YP_003066717.1 CDS METDI1081 NC_012988.1 992839 993624 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(992839..993624) Methylobacterium extorquens DM4 8196003 YP_003066718.1 CDS METDI1082 NC_012988.1 993621 993872 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(993621..993872) Methylobacterium extorquens DM4 8191359 YP_003066719.1 CDS METDI1083 NC_012988.1 994337 994645 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 994337..994645 Methylobacterium extorquens DM4 8191360 YP_003066720.1 CDS gshB NC_012988.1 994947 995909 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 994947..995909 Methylobacterium extorquens DM4 8191361 YP_003066721.1 CDS METDI1085 NC_012988.1 995968 996129 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(995968..996129) Methylobacterium extorquens DM4 8195538 YP_003066722.1 CDS METDI1086 NC_012988.1 996781 998358 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Na+/H+ antiporter complement(996781..998358) Methylobacterium extorquens DM4 8191362 YP_003066723.1 CDS METDI1087 NC_012988.1 998456 999208 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11743193, 11743194; Product type e : enzyme; N-acetylmuramoyl-L-alanine amidase (AGR_C_3833p) complement(998456..999208) Methylobacterium extorquens DM4 8191363 YP_003066724.1 CDS METDI1088 NC_012988.1 999205 999930 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11214968; Product type f : factor; DnaJ-like protein complement(999205..999930) Methylobacterium extorquens DM4 8191364 YP_003066725.1 CDS METDI1089 NC_012988.1 1000133 1000402 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2644204; Product type lp : lipoprotein; putative OsmB-like lipoprotein complement(1000133..1000402) Methylobacterium extorquens DM4 8191365 YP_003066726.1 CDS METDI1090 NC_012988.1 1001212 1001592 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1001212..1001592) Methylobacterium extorquens DM4 8191366 YP_003066727.1 CDS METDI1091 NC_012988.1 1001715 1001966 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1001715..1001966) Methylobacterium extorquens DM4 8191367 YP_003066728.1 CDS dusA NC_012988.1 1002429 1003451 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 22095566; Product type e : enzyme; tRNA-dihydrouridine synthase A 1002429..1003451 Methylobacterium extorquens DM4 8191368 YP_003066729.1 CDS METDI1093 NC_012988.1 1003491 1005635 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL) with PAS sensor; putative membrane-associated protein precursor complement(1003491..1005635) Methylobacterium extorquens DM4 8195317 YP_003066730.1 CDS METDI1094 NC_012988.1 1005950 1006402 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) complement(1005950..1006402) Methylobacterium extorquens DM4 8191369 YP_003066731.1 CDS METDI1095 NC_012988.1 1006464 1006931 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1006464..1006931) Methylobacterium extorquens DM4 8191370 YP_003066732.1 CDS flgE NC_012988.1 1007166 1008548 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type s : structure; putative Flagellar hook protein flgE 1007166..1008548 Methylobacterium extorquens DM4 8191371 YP_003066733.1 CDS flgK NC_012988.1 1008575 1010473 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type s : structure; putative flagellar hook-associated protein 1 FlgK 1008575..1010473 Methylobacterium extorquens DM4 8195397 YP_003066734.1 CDS METDI1098 NC_012988.1 1010488 1012281 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1010488..1012281 Methylobacterium extorquens DM4 8195407 YP_003066735.1 CDS METDI1099 NC_012988.1 1012381 1013670 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1012381..1013670) Methylobacterium extorquens DM4 8191372 YP_003066736.1 CDS prmC NC_012988.1 1014219 1015127 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; protein-(glutamine-N5) methyltransferase, release factor-specific complement(1014219..1015127) Methylobacterium extorquens DM4 8191373 YP_003066737.1 CDS prfA NC_012988.1 1015124 1016209 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1015124..1016209) Methylobacterium extorquens DM4 8195900 YP_003066738.1 CDS METDI1102 NC_012988.1 1016404 1017063 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1016404..1017063) Methylobacterium extorquens DM4 8195894 YP_003066739.1 CDS ptsP NC_012988.1 1017109 1019370 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11287431; Product type e : enzyme; phosphoenolpyruvate-protein phosphotransferase complement(1017109..1019370) Methylobacterium extorquens DM4 8191374 YP_003066740.1 CDS ask NC_012988.1 1019442 1020677 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11287431, 8100567; Product type e : enzyme; aspartate kinase complement(1019442..1020677) Methylobacterium extorquens DM4 8195918 YP_003066741.1 CDS METDI1105 NC_012988.1 1021045 1021782 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16926146; Product type e : enzyme; putative UbiG: ubiquinone biosynthesis O-methyltransferase 1021045..1021782 Methylobacterium extorquens DM4 8195109 YP_003066742.1 CDS METDI1106 NC_012988.1 1021858 1022430 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1021858..1022430 Methylobacterium extorquens DM4 8191375 YP_003066743.1 CDS METDI1108 NC_012988.1 1022570 1023550 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Zn-binding quinone oxidoreductase 1022570..1023550 Methylobacterium extorquens DM4 8191376 YP_003066744.1 CDS ruvC NC_012988.1 1023777 1024385 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1023777..1024385) Methylobacterium extorquens DM4 8191377 YP_003066745.1 CDS yceI NC_012988.1 1024436 1025077 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11298273, 15741337, 1840644, 9298646; Product type c : carrier; polyprenyl-pyrophosphate binding protein complement(1024436..1025077) Methylobacterium extorquens DM4 8196097 YP_003066746.1 CDS ruvA NC_012988.1 1025164 1025790 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1025164..1025790 Methylobacterium extorquens DM4 8196355 YP_003066747.1 CDS METDI1112 NC_012988.1 1025807 1026103 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1025807..1026103) Methylobacterium extorquens DM4 8196095 YP_003066748.1 CDS METDI1113 NC_012988.1 1026181 1026561 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver 1026181..1026561 Methylobacterium extorquens DM4 8191378 YP_003066749.1 CDS METDI1114 NC_012988.1 1026617 1027990 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type r : regulator; response regulator (CheY-like); diguanylate cyclase (GGDEF) and response regulator receiver domains 1026617..1027990 Methylobacterium extorquens DM4 8191379 YP_003066750.1 CDS METDI1115 NC_012988.1 1028008 1028481 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, rrf2 family complement(1028008..1028481) Methylobacterium extorquens DM4 8191380 YP_003066751.1 CDS hmp NC_012988.1 1028576 1029820 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 1028576..1029820 Methylobacterium extorquens DM4 8191381 YP_003066752.1 CDS METDI1117 NC_012988.1 1029848 1030012 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1029848..1030012) Methylobacterium extorquens DM4 8195567 YP_003066753.1 CDS METDI1118 NC_012988.1 1030055 1030399 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1030055..1030399) Methylobacterium extorquens DM4 8191382 YP_003066754.1 CDS METDI1119 NC_012988.1 1030371 1030763 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1030371..1030763) Methylobacterium extorquens DM4 8191383 YP_003066755.1 CDS cysK NC_012988.1 1030852 1031832 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10930739; Product type e : enzyme; subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme complement(1030852..1031832) Methylobacterium extorquens DM4 8191384 YP_003066756.1 CDS METDI1121 NC_012988.1 1032188 1032364 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1032188..1032364) Methylobacterium extorquens DM4 8195257 YP_003066757.1 CDS METDI1122 NC_012988.1 1032543 1033046 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1032543..1033046) Methylobacterium extorquens DM4 8191385 YP_003066758.1 CDS METDI1123 NC_012988.1 1033491 1033769 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1033491..1033769 Methylobacterium extorquens DM4 8191386 YP_003066759.1 CDS METDI1124 NC_012988.1 1033779 1035020 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase complement(1033779..1035020) Methylobacterium extorquens DM4 8191387 YP_003066760.1 CDS qscR NC_012988.1 1035017 1036003 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12562792, 16237034; Product type r : regulator; assimilatory C1 metabolism transcriptional regulator QscR, LysR family complement(1035017..1036003) Methylobacterium extorquens DM4 8191388 YP_003066761.1 CDS cbbF NC_012988.1 1036212 1037267 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1907281; Product type e : enzyme; fructose-1,6-bisphosphatase 1036212..1037267 Methylobacterium extorquens DM4 8195955 YP_003066762.1 CDS prk NC_012988.1 1037415 1038275 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3038847; Product type e : enzyme; phosphoribulokinase 1037415..1038275 Methylobacterium extorquens DM4 8195150 YP_003066763.1 CDS METDI1128 NC_012988.1 1038347 1039243 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1038347..1039243) Methylobacterium extorquens DM4 8195898 YP_003066764.1 CDS METDI1129 NC_012988.1 1039422 1040168 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1039422..1040168) Methylobacterium extorquens DM4 8191389 YP_003066765.1 CDS METDI1130 NC_012988.1 1040274 1040501 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1040274..1040501) Methylobacterium extorquens DM4 8191390 YP_003066766.1 CDS METDI1131 NC_012988.1 1040656 1041468 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Beta-lactamase-like complement(1040656..1041468) Methylobacterium extorquens DM4 8191391 YP_003066767.1 CDS METDI1132 NC_012988.1 1041501 1041674 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1041501..1041674) Methylobacterium extorquens DM4 8191392 YP_003066768.1 CDS METDI1133 NC_012988.1 1041900 1042214 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1041900..1042214 Methylobacterium extorquens DM4 8191393 YP_003066769.1 CDS METDI1134 NC_012988.1 1042236 1043378 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1042236..1043378) Methylobacterium extorquens DM4 8191394 YP_003066770.1 CDS METDI1135 NC_012988.1 1043378 1044754 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative polysaccharide export protein, PST family complement(1043378..1044754) Methylobacterium extorquens DM4 8191395 YP_003066771.1 CDS METDI1136 NC_012988.1 1044873 1045856 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1044873..1045856) Methylobacterium extorquens DM4 8191396 YP_003066772.1 CDS METDI1137 NC_012988.1 1045775 1046914 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9393720; hypothetical protein complement(1045775..1046914) Methylobacterium extorquens DM4 8191397 YP_003066773.1 CDS METDI1138 NC_012988.1 1047103 1047864 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9425311; Product type pe : putative enzyme; putative haloacid dehalogenase family hydrolase (C-terminal domain) complement(1047103..1047864) Methylobacterium extorquens DM4 8191398 YP_003066774.1 CDS rpe NC_012988.1 1047858 1048541 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10191144, 9523694, 9729441; Product type e : enzyme; D-ribulose-5-phosphate 3-epimerase complement(1047858..1048541) Methylobacterium extorquens DM4 8191399 YP_003066775.1 CDS METDI1140 NC_012988.1 1048731 1049345 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; phophinothricin N-acetyltransferase complement(1048731..1049345) Methylobacterium extorquens DM4 8196009 YP_003066776.1 CDS METDI1141 NC_012988.1 1049345 1051690 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; ornithine decarboxylase complement(1049345..1051690) Methylobacterium extorquens DM4 8191400 YP_003066777.1 CDS moaB NC_012988.1 1052427 1052984 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 93368423; Product type e : enzyme; molybdopterin biosynthesis protein B complement(1052427..1052984) Methylobacterium extorquens DM4 8191402 YP_003066778.1 CDS purB NC_012988.1 1053147 1054454 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10673438; Product type e : enzyme; adenylosuccinate lyase 1053147..1054454 Methylobacterium extorquens DM4 8195703 YP_003066779.1 CDS METDI1145 NC_012988.1 1054512 1055369 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7814322; Product type e : enzyme; putative D-amino-acid transaminase (D-alanine aminotransferase) 1054512..1055369 Methylobacterium extorquens DM4 8195930 YP_003066780.1 CDS METDI1146 NC_012988.1 1055442 1055759 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1055442..1055759 Methylobacterium extorquens DM4 8191403 YP_003066781.1 CDS purA NC_012988.1 1055893 1057239 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3058695, 9000627; Product type e : enzyme; adenylosuccinate synthetase 1055893..1057239 Methylobacterium extorquens DM4 8191404 YP_003066782.1 CDS METDI1148 NC_012988.1 1057281 1058759 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1057281..1058759 Methylobacterium extorquens DM4 8195929 YP_003066783.1 CDS rpoH NC_012988.1 1058918 1059811 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(1058918..1059811) Methylobacterium extorquens DM4 8191405 YP_003066784.1 CDS METDI1150 NC_012988.1 1060257 1061186 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex17, IS110 family 1060257..1061186 Methylobacterium extorquens DM4 8196048 YP_003066785.1 CDS METDI1151 NC_012988.1 1061203 1063209 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase/phosphodiesterase, GGDEF and EAL domains complement(1061203..1063209) Methylobacterium extorquens DM4 8191406 YP_003066786.1 CDS METDI1152 NC_012988.1 1063392 1063604 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1063392..1063604) Methylobacterium extorquens DM4 8191407 YP_003066787.1 CDS METDI1153 NC_012988.1 1063643 1063909 D Evidence 6 : Doubtful CDS; hypothetical protein 1063643..1063909 Methylobacterium extorquens DM4 8191408 YP_003066788.1 CDS METDI1154 NC_012988.1 1063945 1064394 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Acetyltransferase complement(1063945..1064394) Methylobacterium extorquens DM4 8191409 YP_003066789.1 CDS METDI1155 NC_012988.1 1064410 1064589 D Evidence 6 : Doubtful CDS; hypothetical protein 1064410..1064589 Methylobacterium extorquens DM4 8191410 YP_003066790.1 CDS rluD NC_012988.1 1064605 1065597 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ribosomal large subunit pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase) complement(1064605..1065597) Methylobacterium extorquens DM4 8191411 YP_003066791.1 CDS METDI1157 NC_012988.1 1065633 1066913 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; phage integrase complement(1065633..1066913) Methylobacterium extorquens DM4 8196000 YP_003066792.1 CDS METDI1158 NC_012988.1 1067461 1068423 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15758242; Product type e : enzyme; phage integrase complement(1067461..1068423) Methylobacterium extorquens DM4 8196224 YP_003066793.1 CDS METDI1159 NC_012988.1 1068555 1068794 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative phage-associated protein complement(1068555..1068794) Methylobacterium extorquens DM4 8191413 YP_003066794.1 CDS METDI1160 NC_012988.1 1069974 1070282 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1069974..1070282 Methylobacterium extorquens DM4 8191414 YP_003066795.1 CDS METDI1161 NC_012988.1 1070386 1070703 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1070386..1070703 Methylobacterium extorquens DM4 8191415 YP_003066796.1 CDS METDI1162 NC_012988.1 1070691 1072967 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2823072; Product type prc : putative receptor; putative ferrichrome-iron receptor protein complement(1070691..1072967) Methylobacterium extorquens DM4 8191416 YP_003066797.1 CDS METDI1163 NC_012988.1 1073195 1074160 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12652904; Product type pe : putative enzyme; putative exported esterase (IroE-like) 1073195..1074160 Methylobacterium extorquens DM4 8191417 YP_003066798.1 CDS METDI1164 NC_012988.1 1075176 1075514 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1075176..1075514 Methylobacterium extorquens DM4 8191418 YP_003066799.1 CDS METDI1165 NC_012988.1 1075908 1076549 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1075908..1076549 Methylobacterium extorquens DM4 8191419 YP_003066800.1 CDS METDI1166 NC_012988.1 1076546 1079182 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-hydrolyzing enzyme 1076546..1079182 Methylobacterium extorquens DM4 8191420 YP_003066801.1 CDS METDI1168 NC_012988.1 1079765 1081510 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase/recombinase 1079765..1081510 Methylobacterium extorquens DM4 8191421 YP_003066802.1 CDS METDI1170 NC_012988.1 1081938 1084061 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase/recombinase 1081938..1084061 Methylobacterium extorquens DM4 8191422 YP_003066803.1 CDS METDI1171 NC_012988.1 1084049 1084249 D Evidence 6 : Doubtful CDS; hypothetical protein 1084049..1084249 Methylobacterium extorquens DM4 8191423 YP_003066804.1 CDS METDI1172 NC_012988.1 1084567 1084764 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1084567..1084764) Methylobacterium extorquens DM4 8191424 YP_003066805.1 CDS METDI1173 NC_012988.1 1084658 1085380 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1084658..1085380) Methylobacterium extorquens DM4 8191425 YP_003066806.1 CDS METDI1174 NC_012988.1 1085561 1086064 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1085561..1086064) Methylobacterium extorquens DM4 8191426 YP_003066807.1 CDS METDI1175 NC_012988.1 1086246 1086458 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional repressor 1086246..1086458 Methylobacterium extorquens DM4 8191427 YP_003066808.1 CDS METDI1176 NC_012988.1 1086681 1087610 D Evidence 2b : Function of strongly homologous gene; PubMedId : 16517654; Product type e : enzyme; transposase of ISMdi4, IS481 family 1086681..1087610 Methylobacterium extorquens DM4 8191428 YP_003066809.1 CDS METDI1179 NC_012988.1 1089097 1089390 D Evidence 6 : Doubtful CDS; hypothetical protein 1089097..1089390 Methylobacterium extorquens DM4 8191431 YP_003066810.1 CDS METDI1180 NC_012988.1 1089412 1090290 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1089412..1090290 Methylobacterium extorquens DM4 8191432 YP_003066811.1 CDS METDI1181 NC_012988.1 1090287 1092338 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-hydrolyzing enzyme 1090287..1092338 Methylobacterium extorquens DM4 8191433 YP_003066812.1 CDS METDI1182 NC_012988.1 1092476 1092937 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1092476..1092937 Methylobacterium extorquens DM4 8191434 YP_003066813.1 CDS METDI1183 NC_012988.1 1093400 1094062 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1093400..1094062 Methylobacterium extorquens DM4 8191435 YP_003066814.1 CDS METDI1184 NC_012988.1 1094076 1094345 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1094076..1094345) Methylobacterium extorquens DM4 8191436 YP_003066815.1 CDS METDI1185 NC_012988.1 1094694 1095083 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1094694..1095083) Methylobacterium extorquens DM4 8191437 YP_003066816.1 CDS METDI1186 NC_012988.1 1095320 1095445 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1095320..1095445) Methylobacterium extorquens DM4 8191438 YP_003066817.1 CDS METDI1187 NC_012988.1 1095480 1096160 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor complement(1095480..1096160) Methylobacterium extorquens DM4 8191439 YP_003066818.1 CDS METDI1188 NC_012988.1 1096639 1098228 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1096639..1098228) Methylobacterium extorquens DM4 8191440 YP_003066819.1 CDS METDI1190 NC_012988.1 1098672 1099154 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1098672..1099154) Methylobacterium extorquens DM4 8191441 YP_003066820.1 CDS METDI1191 NC_012988.1 1099238 1099339 D Evidence 6 : Doubtful CDS; hypothetical protein 1099238..1099339 Methylobacterium extorquens DM4 8191442 YP_003066821.1 CDS METDI1195 NC_012988.1 1101319 1102368 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; carbohydrate-selective porin complement(1101319..1102368) Methylobacterium extorquens DM4 8191445 YP_003066822.1 CDS METDI1196 NC_012988.1 1103420 1103863 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1103420..1103863 Methylobacterium extorquens DM4 8191446 YP_003066823.1 CDS METDI1197 NC_012988.1 1103716 1103997 D Evidence 6 : Doubtful CDS; hypothetical protein 1103716..1103997 Methylobacterium extorquens DM4 8191447 YP_003066824.1 CDS METDI1198 NC_012988.1 1104086 1104370 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1104086..1104370 Methylobacterium extorquens DM4 8191448 YP_003066825.1 CDS METDI1199 NC_012988.1 1105280 1106014 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding response regulator in two-component regulatory system with ArcB or CpxA (putative arcA=cpxC, dye, fexA, msp) 1105280..1106014 Methylobacterium extorquens DM4 8191449 YP_003066826.1 CDS METDI1200 NC_012988.1 1106011 1107345 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase 1106011..1107345 Methylobacterium extorquens DM4 8191450 YP_003066827.1 CDS METDI1201 NC_012988.1 1107575 1107847 D Evidence 6 : Doubtful CDS; hypothetical protein 1107575..1107847 Methylobacterium extorquens DM4 8191451 YP_003066828.1 CDS METDI1202 NC_012988.1 1107835 1108188 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1107835..1108188 Methylobacterium extorquens DM4 8191452 YP_003066829.1 CDS METDI1203 NC_012988.1 1108257 1108490 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1108257..1108490) Methylobacterium extorquens DM4 8191453 YP_003066830.1 CDS METDI1204 NC_012988.1 1108260 1108451 D Evidence 6 : Doubtful CDS; hypothetical protein 1108260..1108451 Methylobacterium extorquens DM4 8191454 YP_003066831.1 CDS METDI1205 NC_012988.1 1108796 1109167 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1108796..1109167 Methylobacterium extorquens DM4 8191455 YP_003066832.1 CDS METDI1206 NC_012988.1 1109292 1110656 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10570969, 16926146; Product type pt : putative transporter; putative secretion protein, putative RND family efflux protein 1109292..1110656 Methylobacterium extorquens DM4 8191456 YP_003066833.1 CDS czcA NC_012988.1 1110668 1113916 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7766206; Product type t : transporter; Cobalt-zinc-cadmium resistance protein czcA (Cation efflux system protein czcA) 1110668..1113916 Methylobacterium extorquens DM4 8191457 YP_003066834.1 CDS METDI1208 NC_012988.1 1113922 1114476 D Evidence 5 : No homology to any previously reported sequences; PubMedId : 11872709; hypothetical protein 1113922..1114476 Methylobacterium extorquens DM4 8195265 YP_003066835.1 CDS czcD NC_012988.1 1114522 1115439 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2678100, 9044283; Product type t : transporter; Cobalt-zinc-cadmium resistance protein czcD (Cation efflux system protein czcD) 1114522..1115439 Methylobacterium extorquens DM4 8191458 YP_003066836.1 CDS METDI1210 NC_012988.1 1115452 1115622 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1115452..1115622 Methylobacterium extorquens DM4 8195269 YP_003066837.1 CDS METDI1211 NC_012988.1 1115945 1116199 D Evidence 6 : Doubtful CDS; hypothetical protein 1115945..1116199 Methylobacterium extorquens DM4 8191459 YP_003066838.1 CDS METDI1212 NC_012988.1 1116438 1116578 D Evidence 6 : Doubtful CDS; hypothetical protein 1116438..1116578 Methylobacterium extorquens DM4 8191460 YP_003066839.1 CDS METDI1213 NC_012988.1 1116575 1118119 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1116575..1118119) Methylobacterium extorquens DM4 8191461 YP_003066840.1 CDS METDI1214 NC_012988.1 1118322 1119062 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1118322..1119062) Methylobacterium extorquens DM4 8191462 YP_003066841.1 CDS METDI1215 NC_012988.1 1119250 1119516 D Evidence 6 : Doubtful CDS; hypothetical protein 1119250..1119516 Methylobacterium extorquens DM4 8191463 YP_003066842.1 CDS METDI1216 NC_012988.1 1119632 1119844 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1119632..1119844) Methylobacterium extorquens DM4 8191464 YP_003066843.1 CDS METDI1218 NC_012988.1 1120205 1120474 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1120205..1120474) Methylobacterium extorquens DM4 8191466 YP_003066844.1 CDS METDI1220 NC_012988.1 1120734 1121024 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1120734..1121024) Methylobacterium extorquens DM4 8191468 YP_003066845.1 CDS METDI1221 NC_012988.1 1121043 1121198 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1121043..1121198) Methylobacterium extorquens DM4 8191469 YP_003066846.1 CDS METDI1222 NC_012988.1 1121255 1121677 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1121255..1121677) Methylobacterium extorquens DM4 8191470 YP_003066847.1 CDS METDI1223 NC_012988.1 1121808 1123142 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17186148, 17293508; Product type t : transporter; putative NcrA-like major facilitator superfamily permease complement(1121808..1123142) Methylobacterium extorquens DM4 8191471 YP_003066848.1 CDS METDI1224 NC_012988.1 1123150 1123419 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17186148, 17293508; Product type pf : putative factor; putative NcrB-like regulator, DUF156 complement(1123150..1123419) Methylobacterium extorquens DM4 8191472 YP_003066849.1 CDS METDI1225 NC_012988.1 1123648 1123986 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative system killer suppression protein 1123648..1123986 Methylobacterium extorquens DM4 8191473 YP_003066850.1 CDS METDI1226 NC_012988.1 1124004 1125098 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8645296; Product type pr : putative regulator; putative plasmid maintenance system antidote protein, HTH DNA-binding domain 1124004..1125098 Methylobacterium extorquens DM4 8191474 YP_003066851.1 CDS METDI1227 NC_012988.1 1125237 1125527 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1125237..1125527 Methylobacterium extorquens DM4 8191475 YP_003066852.1 CDS METDI1228 NC_012988.1 1125530 1126027 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1125530..1126027) Methylobacterium extorquens DM4 8191476 YP_003066853.1 CDS METDI1229 NC_012988.1 1125987 1126418 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1125987..1126418) Methylobacterium extorquens DM4 8191477 YP_003066854.1 CDS METDI1230 NC_012988.1 1126587 1126952 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1126587..1126952) Methylobacterium extorquens DM4 8191478 YP_003066855.1 CDS METDI1231 NC_012988.1 1126986 1130213 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Heavy metal efflux pump CzcA (precursor) complement(1126986..1130213) Methylobacterium extorquens DM4 8191479 YP_003066856.1 CDS METDI1232 NC_012988.1 1130227 1131957 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1130227..1131957) Methylobacterium extorquens DM4 8191480 YP_003066857.1 CDS METDI1233 NC_012988.1 1132040 1132423 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1132040..1132423) Methylobacterium extorquens DM4 8191481 YP_003066858.1 CDS METDI1235 NC_012988.1 1132743 1133009 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1132743..1133009) Methylobacterium extorquens DM4 8191482 YP_003066859.1 CDS METDI1234 NC_012988.1 1132746 1132991 D Evidence 6 : Doubtful CDS; hypothetical protein 1132746..1132991 Methylobacterium extorquens DM4 8191484 YP_003066860.1 CDS METDI1236 NC_012988.1 1133181 1133396 D Evidence 6 : Doubtful CDS; hypothetical protein 1133181..1133396 Methylobacterium extorquens DM4 8191483 YP_003066861.1 CDS METDI1241 NC_012988.1 1134661 1136205 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1134661..1136205) Methylobacterium extorquens DM4 8191488 YP_003066862.1 CDS METDI1242 NC_012988.1 1136269 1136595 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1136269..1136595) Methylobacterium extorquens DM4 8191489 YP_003066863.1 CDS METDI1243 NC_012988.1 1136674 1136772 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1136674..1136772) Methylobacterium extorquens DM4 8191490 YP_003066864.1 CDS METDI1244 NC_012988.1 1137027 1137746 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome c biogenesis protein precursor complement(1137027..1137746) Methylobacterium extorquens DM4 8191491 YP_003066865.1 CDS METDI1245 NC_012988.1 1137753 1138145 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Thioredoxin-related complement(1137753..1138145) Methylobacterium extorquens DM4 8191492 YP_003066866.1 CDS METDI1246 NC_012988.1 1138174 1138974 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1138174..1138974) Methylobacterium extorquens DM4 8191493 YP_003066867.1 CDS METDI1247 NC_012988.1 1139112 1139348 D Evidence 6 : Doubtful CDS; hypothetical protein 1139112..1139348 Methylobacterium extorquens DM4 8191494 YP_003066868.1 CDS METDI1248 NC_012988.1 1139548 1139838 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1139548..1139838 Methylobacterium extorquens DM4 8191495 YP_003066869.1 CDS METDI1249 NC_012988.1 1139835 1140389 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1139835..1140389 Methylobacterium extorquens DM4 8191496 YP_003066870.1 CDS METDI1250 NC_012988.1 1140638 1140814 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1140638..1140814) Methylobacterium extorquens DM4 8191497 YP_003066871.1 CDS METDI1251 NC_012988.1 1141760 1142683 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMex31, IS110 family complement(1141760..1142683) Methylobacterium extorquens DM4 8191498 YP_003066872.1 CDS METDI1255 NC_012988.1 1144811 1145026 R Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein complement(1144811..1145026) Methylobacterium extorquens DM4 8191502 YP_003066873.1 CDS METDI1256 NC_012988.1 1144954 1145121 R Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein complement(1144954..1145121) Methylobacterium extorquens DM4 8191503 YP_003066874.1 CDS METDI1257 NC_012988.1 1145247 1145693 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1145247..1145693 Methylobacterium extorquens DM4 8191504 YP_003066875.1 CDS METDI1259 NC_012988.1 1146046 1147119 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1146046..1147119) Methylobacterium extorquens DM4 8191506 YP_003066876.1 CDS lspA NC_012988.1 1147208 1147729 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative prolipoprotein signal peptidase (SPase II) complement(1147208..1147729) Methylobacterium extorquens DM4 8191507 YP_003066877.1 CDS zntA NC_012988.1 1147726 1149921 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10660539, 12746428, 21305696, 9364914, 9405611, 98070750, 99428388; Product type t : transporter; zinc, cadmium, cobalt and lead efflux system complement(1147726..1149921) Methylobacterium extorquens DM4 8195652 YP_003066878.1 CDS hmrR NC_012988.1 1150022 1150423 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11936079, 12213931; Product type pr : putative regulator; heavy metal resistance transcriptional regulator HmrR, MerR family 1150022..1150423 Methylobacterium extorquens DM4 8196379 YP_003066879.1 CDS METDI1263 NC_012988.1 1150656 1150904 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1150656..1150904) Methylobacterium extorquens DM4 8195569 YP_003066880.1 CDS actP NC_012988.1 1151100 1153520 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11936079, 9930866; Product type t : transporter; cation transporting P-type ATPase complement(1151100..1153520) Methylobacterium extorquens DM4 8191508 YP_003066881.1 CDS METDI1265 NC_012988.1 1153588 1154070 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1153588..1154070) Methylobacterium extorquens DM4 8195059 YP_003066882.1 CDS METDI1267 NC_012988.1 1154125 1154457 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1154125..1154457) Methylobacterium extorquens DM4 8191509 YP_003066883.1 CDS METDI1268 NC_012988.1 1154637 1155035 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1154637..1155035) Methylobacterium extorquens DM4 8191510 YP_003066884.1 CDS METDI1269 NC_012988.1 1155062 1155427 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1155062..1155427) Methylobacterium extorquens DM4 8191511 YP_003066885.1 CDS METDI1270 NC_012988.1 1155447 1158596 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Heavy metal efflux pump CzcA (precursor) complement(1155447..1158596) Methylobacterium extorquens DM4 8191512 YP_003066886.1 CDS METDI1271 NC_012988.1 1158610 1160349 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1158610..1160349) Methylobacterium extorquens DM4 8191513 YP_003066887.1 CDS METDI1272 NC_012988.1 1160430 1160903 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1160430..1160903) Methylobacterium extorquens DM4 8191514 YP_003066888.1 CDS METDI1273 NC_012988.1 1160435 1160797 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1160435..1160797) Methylobacterium extorquens DM4 8191515 YP_003066889.1 CDS copP NC_012988.1 1160995 1161207 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12213931; Product type pf : putative factor; CopP metal-binding protein, putative exported protein complement(1160995..1161207) Methylobacterium extorquens DM4 8191516 YP_003066890.1 CDS METDI1275 NC_012988.1 1161654 1162328 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1161654..1162328 Methylobacterium extorquens DM4 8195203 YP_003066891.1 CDS METDI1276 NC_012988.1 1162342 1162818 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1162342..1162818) Methylobacterium extorquens DM4 8191517 YP_003066892.1 CDS cusA NC_012988.1 1162838 1166011 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11399769, 12813074, 1711024, 20461235, 21125583, 21178899, 21450803, 79844; Product type t : transporter; outer membrane copper (silver) and drug transport protein (RND family) complement(1162838..1166011) Methylobacterium extorquens DM4 8191518 YP_003066893.1 CDS METDI1278 NC_012988.1 1166008 1167525 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative secretion protein precursor, putative RND family efflux protein complement(1166008..1167525) Methylobacterium extorquens DM4 8195229 YP_003066894.1 CDS METDI1279 NC_012988.1 1167522 1167926 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1167522..1167926) Methylobacterium extorquens DM4 8191519 YP_003066895.1 CDS METDI1280 NC_012988.1 1168008 1168406 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1168008..1168406) Methylobacterium extorquens DM4 8191520 YP_003066896.1 CDS METDI1281 NC_012988.1 1169202 1169396 D Evidence 6 : Doubtful CDS; hypothetical protein 1169202..1169396 Methylobacterium extorquens DM4 8191521 YP_003066897.1 CDS METDI1282 NC_012988.1 1169453 1169626 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1169453..1169626) Methylobacterium extorquens DM4 8191522 YP_003066898.1 CDS METDI1283 NC_012988.1 1170165 1170491 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1170165..1170491 Methylobacterium extorquens DM4 8191523 YP_003066899.1 CDS METDI1284 NC_012988.1 1170720 1171064 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1170720..1171064 Methylobacterium extorquens DM4 8191524 YP_003066900.1 CDS METDI1285 NC_012988.1 1171061 1171507 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1171061..1171507) Methylobacterium extorquens DM4 8191525 YP_003066901.1 CDS METDI1287 NC_012988.1 1173291 1173812 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1173291..1173812) Methylobacterium extorquens DM4 8191527 YP_003066902.1 CDS METDI1290 NC_012988.1 1175709 1175879 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1175709..1175879) Methylobacterium extorquens DM4 8195943 YP_003066903.1 CDS METDI1291 NC_012988.1 1176037 1179213 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Alkaline phosphatase; Hemolysin-type calcium-binding domain 1176037..1179213 Methylobacterium extorquens DM4 8191529 YP_003066904.1 CDS METDI1292 NC_012988.1 1179442 1179723 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) 1179442..1179723 Methylobacterium extorquens DM4 8191530 YP_003066905.1 CDS METDI1293 NC_012988.1 1179831 1180583 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) 1179831..1180583 Methylobacterium extorquens DM4 8191531 YP_003066906.1 CDS METDI1294 NC_012988.1 1180769 1181698 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex17, IS110 family 1180769..1181698 Methylobacterium extorquens DM4 8191532 YP_003066907.1 CDS METDI1295 NC_012988.1 1182098 1182352 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1182098..1182352 Methylobacterium extorquens DM4 8191533 YP_003066908.1 CDS METDI1296 NC_012988.1 1182359 1182616 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1182359..1182616) Methylobacterium extorquens DM4 8191534 YP_003066909.1 CDS METDI1297 NC_012988.1 1182922 1183113 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1182922..1183113 Methylobacterium extorquens DM4 8191535 YP_003066910.1 CDS METDI1298 NC_012988.1 1183589 1185808 D Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; TonB-dependent siderophore receptor 1183589..1185808 Methylobacterium extorquens DM4 8195032 YP_003066911.1 CDS METDI1299 NC_012988.1 1185812 1187251 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1185812..1187251 Methylobacterium extorquens DM4 8191537 YP_003066912.1 CDS METDI1300 NC_012988.1 1187646 1187780 D Evidence 6 : Doubtful CDS; hypothetical protein 1187646..1187780 Methylobacterium extorquens DM4 8191538 YP_003066913.1 CDS METDI1301 NC_012988.1 1187833 1188216 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1187833..1188216) Methylobacterium extorquens DM4 8191539 YP_003066914.1 CDS METDI1302 NC_012988.1 1188850 1189830 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ArsB-like efflux protein complement(1188850..1189830) Methylobacterium extorquens DM4 8191540 YP_003066915.1 CDS arsR NC_012988.1 1189827 1190213 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346, 12829264, 9537360; Product type r : regulator; transcriptional regulator, ArsR family complement(1189827..1190213) Methylobacterium extorquens DM4 8191541 YP_003066916.1 CDS METDI1304 NC_012988.1 1190645 1192351 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative methyl-accepting chemotaxis sensory transducer precursor 1190645..1192351 Methylobacterium extorquens DM4 8195104 YP_003066917.1 CDS METDI1305 NC_012988.1 1192948 1193085 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1192948..1193085 Methylobacterium extorquens DM4 8191542 YP_003066918.1 CDS arsH NC_012988.1 1193133 1193879 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346; Product type e : enzyme; NADPH-dependent FMN reductase complement(1193133..1193879) Methylobacterium extorquens DM4 8191543 YP_003066919.1 CDS arsR NC_012988.1 1193930 1194289 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346, 12829264, 9537360; Product type r : regulator; transcriptional regulator, ArsR family 1193930..1194289 Methylobacterium extorquens DM4 8195101 YP_003066920.1 CDS arsC NC_012988.1 1194282 1194809 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11573087, 16905151; Product type e : enzyme; arsenate reductase / phosphotyrosine protein phosphatase 1194282..1194809 Methylobacterium extorquens DM4 8195105 YP_003066921.1 CDS arsC NC_012988.1 1194809 1195234 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16905151, 17432936; Product type e : enzyme; arsenate reductase (glutaredoxin family) 1194809..1195234 Methylobacterium extorquens DM4 8195097 YP_003066922.1 CDS METDI1311 NC_012988.1 1195990 1196271 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) 1195990..1196271 Methylobacterium extorquens DM4 8191544 YP_003066923.1 CDS METDI1312 NC_012988.1 1196379 1197131 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) 1196379..1197131 Methylobacterium extorquens DM4 8191545 YP_003066924.1 CDS METDI1313 NC_012988.1 1197317 1198246 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex17, IS110 family 1197317..1198246 Methylobacterium extorquens DM4 8191546 YP_003066925.1 CDS METDI1314 NC_012988.1 1198333 1198572 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1198333..1198572 Methylobacterium extorquens DM4 8191547 YP_003066926.1 CDS METDI1315 NC_012988.1 1198729 1199019 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1198729..1199019) Methylobacterium extorquens DM4 8191548 YP_003066927.1 CDS METDI1316 NC_012988.1 1199111 1199380 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1199111..1199380) Methylobacterium extorquens DM4 8191549 YP_003066928.1 CDS METDI1317 NC_012988.1 1199730 1200155 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1199730..1200155) Methylobacterium extorquens DM4 8191550 YP_003066929.1 CDS METDI1318 NC_012988.1 1200356 1200622 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1200356..1200622) Methylobacterium extorquens DM4 8191551 YP_003066930.1 CDS METDI1319 NC_012988.1 1201006 1201443 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1201006..1201443 Methylobacterium extorquens DM4 8191552 YP_003066931.1 CDS METDI1320 NC_012988.1 1201530 1203281 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1201530..1203281 Methylobacterium extorquens DM4 8191553 YP_003066932.1 CDS czcA NC_012988.1 1203294 1206437 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Heavy metal efflux pump CzcA (precursor) 1203294..1206437 Methylobacterium extorquens DM4 8191554 YP_003066933.1 CDS METDI1322 NC_012988.1 1206471 1206836 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1206471..1206836 Methylobacterium extorquens DM4 8195266 YP_003066934.1 CDS METDI1323 NC_012988.1 1206859 1207293 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12670971; hypothetical protein 1206859..1207293 Methylobacterium extorquens DM4 8191555 YP_003066935.1 CDS METDI1324 NC_012988.1 1207485 1207817 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1207485..1207817 Methylobacterium extorquens DM4 8191556 YP_003066936.1 CDS METDI1325 NC_012988.1 1207841 1208074 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1207841..1208074 Methylobacterium extorquens DM4 8191557 YP_003066937.1 CDS METDI1326 NC_012988.1 1208240 1210669 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11238972, 16151171; Product type t : transporter; cation transporting P-type ATPase 1208240..1210669 Methylobacterium extorquens DM4 8191558 YP_003066938.1 CDS METDI1327 NC_012988.1 1210980 1211456 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1210980..1211456 Methylobacterium extorquens DM4 8191559 YP_003066939.1 CDS METDI1328 NC_012988.1 1211520 1211711 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1211520..1211711) Methylobacterium extorquens DM4 8191560 YP_003066940.1 CDS METDI1329 NC_012988.1 1211791 1212006 D Evidence 6 : Doubtful CDS; hypothetical protein 1211791..1212006 Methylobacterium extorquens DM4 8191561 YP_003066941.1 CDS METDI1335 NC_012988.1 1213441 1215444 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative outer membrane receptor for iron transport 1213441..1215444 Methylobacterium extorquens DM4 8191566 YP_003066942.1 CDS METDI1336 NC_012988.1 1215346 1215594 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1215346..1215594) Methylobacterium extorquens DM4 8191567 YP_003066943.1 CDS METDI1338 NC_012988.1 1216898 1217200 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1216898..1217200) Methylobacterium extorquens DM4 8191568 YP_003066944.1 CDS METDI1339 NC_012988.1 1217834 1218121 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1217834..1218121) Methylobacterium extorquens DM4 8191569 YP_003066945.1 CDS METDI1340 NC_012988.1 1218157 1219449 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1218157..1219449 Methylobacterium extorquens DM4 8191570 YP_003066946.1 CDS METDI1341 NC_012988.1 1219900 1221357 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1219900..1221357 Methylobacterium extorquens DM4 8191571 YP_003066947.1 CDS METDI1342 NC_012988.1 1221392 1221607 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1221392..1221607) Methylobacterium extorquens DM4 8191572 YP_003066948.1 CDS METDI1343 NC_012988.1 1221658 1222542 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1221658..1222542) Methylobacterium extorquens DM4 8191573 YP_003066949.1 CDS METDI1345 NC_012988.1 1223571 1224323 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1223571..1224323) Methylobacterium extorquens DM4 8191575 YP_003066950.1 CDS METDI1346 NC_012988.1 1224397 1224747 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1224397..1224747) Methylobacterium extorquens DM4 8191576 YP_003066951.1 CDS METDI1347 NC_012988.1 1224462 1224518 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1224462..1224518) Methylobacterium extorquens DM4 8191577 YP_003066952.1 CDS METDI1348 NC_012988.1 1224816 1225250 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1224816..1225250) Methylobacterium extorquens DM4 8191578 YP_003066953.1 CDS METDI1349 NC_012988.1 1225930 1226400 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1225930..1226400) Methylobacterium extorquens DM4 8191579 YP_003066954.1 CDS cusA NC_012988.1 1226456 1229620 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11399769, 12813074, 1711024, 20461235, 21125583, 21178899, 21450803; Product type t : transporter; copper/silver efflux system, membrane component complement(1226456..1229620) Methylobacterium extorquens DM4 8191580 YP_003066955.1 CDS METDI1351 NC_012988.1 1229617 1231143 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative secretion protein, putative RND family efflux protein complement(1229617..1231143) Methylobacterium extorquens DM4 8195230 YP_003066956.1 CDS METDI1352 NC_012988.1 1231143 1231691 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1231143..1231691) Methylobacterium extorquens DM4 8191581 YP_003066957.1 CDS METDI1353 NC_012988.1 1231936 1232337 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1231936..1232337) Methylobacterium extorquens DM4 8191582 YP_003066958.1 CDS METDI1354 NC_012988.1 1232474 1232812 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1232474..1232812) Methylobacterium extorquens DM4 8191583 YP_003066959.1 CDS METDI1355 NC_012988.1 1233358 1233576 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1233358..1233576 Methylobacterium extorquens DM4 8191584 YP_003066960.1 CDS METDI1356 NC_012988.1 1233616 1233888 D Evidence 6 : Doubtful CDS; hypothetical protein 1233616..1233888 Methylobacterium extorquens DM4 8191585 YP_003066961.1 CDS METDI1357 NC_012988.1 1233933 1234583 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1233933..1234583) Methylobacterium extorquens DM4 8191586 YP_003066962.1 CDS METDI1358 NC_012988.1 1234580 1235188 R Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor complement(1234580..1235188) Methylobacterium extorquens DM4 8191587 YP_003066963.1 CDS METDI1359 NC_012988.1 1235603 1235818 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1235603..1235818) Methylobacterium extorquens DM4 8191588 YP_003066964.1 CDS METDI1360 NC_012988.1 1236147 1236518 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1236147..1236518 Methylobacterium extorquens DM4 8191589 YP_003066965.1 CDS METDI1361 NC_012988.1 1237825 1238259 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1237825..1238259 Methylobacterium extorquens DM4 8191590 YP_003066966.1 CDS METDI1362 NC_012988.1 1238328 1238750 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1238328..1238750 Methylobacterium extorquens DM4 8191591 YP_003066967.1 CDS METDI1363 NC_012988.1 1238813 1240357 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative outer membrane efflux protein; putative copper tolerance protein 1238813..1240357 Methylobacterium extorquens DM4 8191592 YP_003066968.1 CDS METDI1364 NC_012988.1 1240390 1241811 D Evidence 2b : Function of strongly homologous gene; PubMedId : 17359266; Product type e : enzyme; multicopper oxidase, putative manganese-oxidizing multicopper oxidase 1240390..1241811 Methylobacterium extorquens DM4 8191593 YP_003066969.1 CDS METDI1365 NC_012988.1 1241986 1242270 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1241986..1242270 Methylobacterium extorquens DM4 8191594 YP_003066970.1 CDS METDI1366 NC_012988.1 1242342 1243046 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1242342..1243046 Methylobacterium extorquens DM4 8191595 YP_003066971.1 CDS METDI1367 NC_012988.1 1243152 1243790 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome c family protein precursor 1243152..1243790 Methylobacterium extorquens DM4 8191596 YP_003066972.1 CDS METDI1368 NC_012988.1 1243924 1244304 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1243924..1244304 Methylobacterium extorquens DM4 8191597 YP_003066973.1 CDS METDI1369 NC_012988.1 1244667 1244954 D Evidence 6 : Doubtful CDS; hypothetical protein 1244667..1244954 Methylobacterium extorquens DM4 8191598 YP_003066974.1 CDS METDI1370 NC_012988.1 1245246 1245557 R Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein complement(1245246..1245557) Methylobacterium extorquens DM4 8191599 YP_003066975.1 CDS METDI1371 NC_012988.1 1245853 1246482 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15064768; Product type r : regulator; transcriptional regulator, GntR family complement(1245853..1246482) Methylobacterium extorquens DM4 8191600 YP_003066976.1 CDS METDI1372 NC_012988.1 1246677 1248020 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7592429; Product type pt : putative transporter; putative tartrate transporter ttuB 1246677..1248020 Methylobacterium extorquens DM4 8191601 YP_003066977.1 CDS ttuC NC_012988.1 1248062 1249138 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10568751, 8969502, 9384377; Product type e : enzyme; Tartrate dehydrogenase/decarboxylase (TDH) (D-malate dehydrogenase [decarboxylating]) 1248062..1249138 Methylobacterium extorquens DM4 8191602 YP_003066978.1 CDS METDI1374 NC_012988.1 1249143 1250402 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycerate kinase 1249143..1250402 Methylobacterium extorquens DM4 8196287 YP_003066979.1 CDS pyk NC_012988.1 1250427 1251854 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7592429; Product type e : enzyme; pyruvate kinase 1250427..1251854 Methylobacterium extorquens DM4 8191603 YP_003066980.1 CDS METDI1376 NC_012988.1 1252306 1252518 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1252306..1252518 Methylobacterium extorquens DM4 8195944 YP_003066981.1 CDS arsH NC_012988.1 1252566 1253312 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346; Product type e : enzyme; NADPH-dependent FMN reductase complement(1252566..1253312) Methylobacterium extorquens DM4 8191604 YP_003066982.1 CDS arsRC NC_012988.1 1253363 1254241 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10788346, 11573087, 12829264, 16905151, 9537360; Product type e : enzyme; bifunctional protein, N-terminal transcriptional regulator, ArsR family and C-terminal arsenate reductase/phosphotyrosine protein phosphatase 1253363..1254241 Methylobacterium extorquens DM4 8195102 YP_003066983.1 CDS arsC NC_012988.1 1254241 1254666 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16905151, 17432936; Product type e : enzyme; arsenate reductase (glutaredoxin family) 1254241..1254666 Methylobacterium extorquens DM4 8195107 YP_003066984.1 CDS acr3 NC_012988.1 1254675 1255742 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; arsenite efflux pump ACR3 1254675..1255742 Methylobacterium extorquens DM4 8195099 YP_003066985.1 CDS METDI1381 NC_012988.1 1255732 1256907 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Major Facilitator Family (MFS) transporter 1255732..1256907 Methylobacterium extorquens DM4 8195053 YP_003066986.1 CDS METDI1382 NC_012988.1 1257095 1257367 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1257095..1257367 Methylobacterium extorquens DM4 8191605 YP_003066987.1 CDS METDI1383 NC_012988.1 1257522 1259276 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; peptidase S8/S53 subtilisin kexin sedolisin 1257522..1259276 Methylobacterium extorquens DM4 8191606 YP_003066988.1 CDS METDI1384 NC_012988.1 1259374 1259934 D Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1259374..1259934 Methylobacterium extorquens DM4 8191607 YP_003066989.1 CDS METDI1385 NC_012988.1 1259921 1260628 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1259921..1260628 Methylobacterium extorquens DM4 8191608 YP_003066990.1 CDS METDI1386 NC_012988.1 1260644 1260952 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1260644..1260952 Methylobacterium extorquens DM4 8191609 YP_003066991.1 CDS METDI1389 NC_012988.1 1262124 1262366 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1262124..1262366) Methylobacterium extorquens DM4 8191612 YP_003066992.1 CDS METDI1391 NC_012988.1 1262800 1263024 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1262800..1263024 Methylobacterium extorquens DM4 8191613 YP_003066993.1 CDS METDI1392 NC_012988.1 1263278 1263562 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1263278..1263562 Methylobacterium extorquens DM4 8191614 YP_003066994.1 CDS METDI1394 NC_012988.1 1263630 1263974 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1263630..1263974) Methylobacterium extorquens DM4 8191615 YP_003066995.1 CDS METDI1395 NC_012988.1 1264163 1264687 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1264163..1264687) Methylobacterium extorquens DM4 8191616 YP_003066996.1 CDS czcA NC_012988.1 1264831 1268091 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7766206; Product type t : transporter; Cation efflux system protein czcA complement(1264831..1268091) Methylobacterium extorquens DM4 8191617 YP_003066997.1 CDS METDI1397 NC_012988.1 1268103 1269419 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative secretion protein, putative RND family efflux protein complement(1268103..1269419) Methylobacterium extorquens DM4 8195267 YP_003066998.1 CDS METDI1398 NC_012988.1 1269567 1269953 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1269567..1269953) Methylobacterium extorquens DM4 8191618 YP_003066999.1 CDS METDI1399 NC_012988.1 1269969 1270379 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1269969..1270379) Methylobacterium extorquens DM4 8191619 YP_003067000.1 CDS METDI1400 NC_012988.1 1270482 1270964 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1270482..1270964) Methylobacterium extorquens DM4 8191620 YP_003067001.1 CDS METDI1401 NC_012988.1 1271062 1271484 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11936079, 12213931; Product type pr : putative regulator; putative transcriptional regulator, MerR family complement(1271062..1271484) Methylobacterium extorquens DM4 8191621 YP_003067002.1 CDS zntA NC_012988.1 1271532 1273682 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10660539; Product type t : transporter; Zinc, cobalt and lead efflux system (P-type ATPase) 1271532..1273682 Methylobacterium extorquens DM4 8191622 YP_003067003.1 CDS METDI1403 NC_012988.1 1273695 1274303 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1273695..1274303 Methylobacterium extorquens DM4 8196380 YP_003067004.1 CDS METDI1404 NC_012988.1 1274427 1275095 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1274427..1275095 Methylobacterium extorquens DM4 8191623 YP_003067005.1 CDS METDI1405 NC_012988.1 1275026 1275340 D Evidence 6 : Doubtful CDS; hypothetical protein 1275026..1275340 Methylobacterium extorquens DM4 8191624 YP_003067006.1 CDS METDI1407 NC_012988.1 1276251 1277003 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) complement(1276251..1277003) Methylobacterium extorquens DM4 8191626 YP_003067007.1 CDS METDI1408 NC_012988.1 1277111 1277392 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) complement(1277111..1277392) Methylobacterium extorquens DM4 8191627 YP_003067008.1 CDS METDI1410 NC_012988.1 1278382 1279395 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi14, IS110 family complement(1278382..1279395) Methylobacterium extorquens DM4 8191629 YP_003067009.1 CDS METDI1411 NC_012988.1 1279792 1280112 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1279792..1280112) Methylobacterium extorquens DM4 8191630 YP_003067010.1 CDS METDI1412 NC_012988.1 1280352 1280507 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1280352..1280507) Methylobacterium extorquens DM4 8191631 YP_003067011.1 CDS METDI1413 NC_012988.1 1280610 1282769 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative plasmid stabilization protein (plasmid partitioning) complement(1280610..1282769) Methylobacterium extorquens DM4 8191632 YP_003067012.1 CDS ardC NC_012988.1 1283121 1284128 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; Antirestriction protein (ardC) complement(1283121..1284128) Methylobacterium extorquens DM4 8191633 YP_003067013.1 CDS METDI1416 NC_012988.1 1284771 1285856 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi10, IS110 family complement(1284771..1285856) Methylobacterium extorquens DM4 8191634 YP_003067014.1 CDS METDI1418 NC_012988.1 1286120 1286362 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1286120..1286362) Methylobacterium extorquens DM4 8191636 YP_003067015.1 CDS METDI1419 NC_012988.1 1286323 1286532 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1286323..1286532) Methylobacterium extorquens DM4 8191637 YP_003067016.1 CDS METDI1420 NC_012988.1 1286664 1286918 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1286664..1286918) Methylobacterium extorquens DM4 8191638 YP_003067017.1 CDS METDI1421 NC_012988.1 1287150 1287668 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi22, IS5 family complement(1287150..1287668) Methylobacterium extorquens DM4 8191639 YP_003067018.1 CDS METDI1423 NC_012988.1 1288804 1289829 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi12, IS110 family complement(1288804..1289829) Methylobacterium extorquens DM4 8191641 YP_003067019.1 CDS METDI1424 NC_012988.1 1289887 1290282 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1289887..1290282 Methylobacterium extorquens DM4 8191642 YP_003067020.1 CDS METDI1425 NC_012988.1 1290482 1290760 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1290482..1290760 Methylobacterium extorquens DM4 8191643 YP_003067021.1 CDS METDI1426 NC_012988.1 1291281 1293413 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1291281..1293413 Methylobacterium extorquens DM4 8191644 YP_003067022.1 CDS METDI1427 NC_012988.1 1293490 1293780 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1293490..1293780) Methylobacterium extorquens DM4 8191645 YP_003067023.1 CDS METDI1428 NC_012988.1 1294532 1294867 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1294532..1294867) Methylobacterium extorquens DM4 8191646 YP_003067024.1 CDS METDI1429 NC_012988.1 1295178 1296317 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi9, IS110 family 1295178..1296317 Methylobacterium extorquens DM4 8191647 YP_003067025.1 CDS copB NC_012988.1 1296961 1297770 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8594334; Product type t : transporter; Copper resistance protein CopB precursor complement(1296961..1297770) Methylobacterium extorquens DM4 8191648 YP_003067026.1 CDS copA NC_012988.1 1297781 1299859 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Copper resistance protein A precursor complement(1297781..1299859) Methylobacterium extorquens DM4 8195202 YP_003067027.1 CDS METDI1433 NC_012988.1 1300326 1300520 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1300326..1300520 Methylobacterium extorquens DM4 8195201 YP_003067028.1 CDS METDI1434 NC_012988.1 1300462 1300725 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative periplasmic copper-binding protein (cusF-like domain) 1300462..1300725 Methylobacterium extorquens DM4 8191649 YP_003067029.1 CDS METDI1435 NC_012988.1 1300973 1301329 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1300973..1301329 Methylobacterium extorquens DM4 8191650 YP_003067030.1 CDS METDI1436 NC_012988.1 1301360 1301827 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1301360..1301827 Methylobacterium extorquens DM4 8191651 YP_003067031.1 CDS METDI1437 NC_012988.1 1301770 1302492 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Transcriptional regulator, Crp/Fnr family complement(1301770..1302492) Methylobacterium extorquens DM4 8191652 YP_003067032.1 CDS METDI1438 NC_012988.1 1302829 1303440 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1302829..1303440 Methylobacterium extorquens DM4 8191653 YP_003067033.1 CDS METDI1439 NC_012988.1 1303760 1305457 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10651802; Product type pe : putative enzyme; putative HCP oxidoreductase, NADH-dependent (hcr-like domain); ferredoxin reductase-like, C-terminal NADP-linked domain 1303760..1305457 Methylobacterium extorquens DM4 8191654 YP_003067034.1 CDS METDI1440 NC_012988.1 1305412 1306209 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1305412..1306209 Methylobacterium extorquens DM4 8191655 YP_003067035.1 CDS METDI1441 NC_012988.1 1306206 1306979 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1306206..1306979 Methylobacterium extorquens DM4 8191656 YP_003067036.1 CDS METDI1442 NC_012988.1 1307896 1308360 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1307896..1308360 Methylobacterium extorquens DM4 8191657 YP_003067037.1 CDS pta NC_012988.1 1308591 1309685 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phosphate acetyltransferase complement(1308591..1309685) Methylobacterium extorquens DM4 8191658 YP_003067038.1 CDS METDI1444 NC_012988.1 1309682 1310893 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetate kinase, propionate kinase complement(1309682..1310893) Methylobacterium extorquens DM4 8195914 YP_003067039.1 CDS METDI1445 NC_012988.1 1310897 1312708 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1310897..1312708) Methylobacterium extorquens DM4 8191659 YP_003067040.1 CDS METDI1446 NC_012988.1 1312721 1312894 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1312721..1312894) Methylobacterium extorquens DM4 8191660 YP_003067041.1 CDS METDI1447 NC_012988.1 1312905 1313594 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(1312905..1313594) Methylobacterium extorquens DM4 8191661 YP_003067042.1 CDS METDI1448 NC_012988.1 1313614 1313865 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1313614..1313865) Methylobacterium extorquens DM4 8191662 YP_003067043.1 CDS METDI1449 NC_012988.1 1314044 1314730 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1314044..1314730 Methylobacterium extorquens DM4 8191663 YP_003067044.1 CDS METDI1450 NC_012988.1 1314860 1315027 D Evidence 6 : Doubtful CDS; hypothetical protein 1314860..1315027 Methylobacterium extorquens DM4 8191664 YP_003067045.1 CDS METDI1451 NC_012988.1 1315294 1316736 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1315294..1316736 Methylobacterium extorquens DM4 8191665 YP_003067046.1 CDS METDI1452 NC_012988.1 1316769 1316981 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1316769..1316981 Methylobacterium extorquens DM4 8191666 YP_003067047.1 CDS METDI1455 NC_012988.1 1318235 1318957 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1318235..1318957 Methylobacterium extorquens DM4 8191669 YP_003067048.1 CDS METDI1456 NC_012988.1 1318686 1319057 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1318686..1319057 Methylobacterium extorquens DM4 8191670 YP_003067049.1 CDS METDI1457 NC_012988.1 1319044 1319796 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) complement(1319044..1319796) Methylobacterium extorquens DM4 8191671 YP_003067050.1 CDS METDI1458 NC_012988.1 1319904 1320185 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) complement(1319904..1320185) Methylobacterium extorquens DM4 8191672 YP_003067051.1 CDS METDI1460 NC_012988.1 1320888 1321283 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1320888..1321283 Methylobacterium extorquens DM4 8191674 YP_003067052.1 CDS opdE NC_012988.1 1321375 1322607 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Transcription regulatory protein 1321375..1322607 Methylobacterium extorquens DM4 8191675 YP_003067053.1 CDS METDI1462 NC_012988.1 1322679 1323446 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR 1322679..1323446 Methylobacterium extorquens DM4 8195810 YP_003067054.1 CDS METDI1463 NC_012988.1 1323590 1323961 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1323590..1323961 Methylobacterium extorquens DM4 8191676 YP_003067055.1 CDS METDI1464 NC_012988.1 1323972 1325027 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11418146, 17166853; Product type pe : putative enzyme; putative lactonase precursor 1323972..1325027 Methylobacterium extorquens DM4 8191677 YP_003067056.1 CDS METDI1465 NC_012988.1 1325091 1325702 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1325091..1325702 Methylobacterium extorquens DM4 8191678 YP_003067057.1 CDS METDI1466 NC_012988.1 1325474 1325977 D Evidence 6 : Doubtful CDS; hypothetical protein 1325474..1325977 Methylobacterium extorquens DM4 8191679 YP_003067058.1 CDS METDI1467 NC_012988.1 1325808 1326467 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 1325808..1326467 Methylobacterium extorquens DM4 8191680 YP_003067059.1 CDS METDI1468 NC_012988.1 1326480 1327373 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(1326480..1327373) Methylobacterium extorquens DM4 8191681 YP_003067060.1 CDS METDI1469 NC_012988.1 1327666 1328256 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, 2Fe-2S subunit 1327666..1328256 Methylobacterium extorquens DM4 8191682 YP_003067061.1 CDS METDI1470 NC_012988.1 1328040 1329203 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, FAD-binding subunit 1328040..1329203 Methylobacterium extorquens DM4 8191683 YP_003067062.1 CDS METDI1471 NC_012988.1 1329207 1331426 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, molybdopterin-binding subunit 1329207..1331426 Methylobacterium extorquens DM4 8191684 YP_003067063.1 CDS METDI1472 NC_012988.1 1331604 1331930 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1331604..1331930 Methylobacterium extorquens DM4 8191685 YP_003067064.1 CDS METDI1473 NC_012988.1 1331985 1332161 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1331985..1332161 Methylobacterium extorquens DM4 8191686 YP_003067065.1 CDS MEDTI5946 NC_012988.1 1332237 1332638 D Evidence 6 : Doubtful CDS; hypothetical protein 1332237..1332638 Methylobacterium extorquens DM4 8191687 YP_003067066.1 CDS METDI1474 NC_012988.1 1332884 1333234 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1332884..1333234 Methylobacterium extorquens DM4 8190528 YP_003067067.1 CDS METDI1475 NC_012988.1 1333806 1334840 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative GTPase 1333806..1334840 Methylobacterium extorquens DM4 8191688 YP_003067068.1 CDS METDI1481 NC_012988.1 1341266 1342435 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NADH dehydrogenase (ubiquinone) 1 alpha subcomplex complement(1341266..1342435) Methylobacterium extorquens DM4 8196086 YP_003067069.1 CDS METDI1482 NC_012988.1 1342676 1343341 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1342676..1343341) Methylobacterium extorquens DM4 8191690 YP_003067070.1 CDS METDI1483 NC_012988.1 1343583 1344752 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9603882; Product type pt : putative transporter; putative transporter, major facilitator superfamily 1343583..1344752 Methylobacterium extorquens DM4 8191691 YP_003067071.1 CDS priA NC_012988.1 1344836 1347013 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1344836..1347013 Methylobacterium extorquens DM4 8191692 YP_003067072.1 CDS METDI1485 NC_012988.1 1347098 1347460 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1347098..1347460 Methylobacterium extorquens DM4 8195897 YP_003067073.1 CDS METDI1486 NC_012988.1 1347549 1347929 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1347549..1347929) Methylobacterium extorquens DM4 8191693 YP_003067074.1 CDS METDI1487 NC_012988.1 1348352 1348603 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1348352..1348603) Methylobacterium extorquens DM4 8191694 YP_003067075.1 CDS METDI1488 NC_012988.1 1348721 1349731 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR complement(1348721..1349731) Methylobacterium extorquens DM4 8191695 YP_003067076.1 CDS METDI1489 NC_012988.1 1349877 1350488 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Isochorismatase hydrolase complement(1349877..1350488) Methylobacterium extorquens DM4 8191696 YP_003067077.1 CDS METDI1490 NC_012988.1 1350521 1351645 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative zinc-containing alcohol dehydrogenase complement(1350521..1351645) Methylobacterium extorquens DM4 8191697 YP_003067078.1 CDS METDI1491 NC_012988.1 1351823 1352431 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1351823..1352431) Methylobacterium extorquens DM4 8191698 YP_003067079.1 CDS METDI1492 NC_012988.1 1352697 1353509 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR 1352697..1353509 Methylobacterium extorquens DM4 8191699 YP_003067080.1 CDS METDI1493 NC_012988.1 1353577 1354569 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 1353577..1354569 Methylobacterium extorquens DM4 8191700 YP_003067081.1 CDS METDI1494 NC_012988.1 1354652 1354831 D Evidence 6 : Doubtful CDS; hypothetical protein 1354652..1354831 Methylobacterium extorquens DM4 8191701 YP_003067082.1 CDS METDI1495 NC_012988.1 1354969 1356600 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ubiquinone biosynthesis protein complement(1354969..1356600) Methylobacterium extorquens DM4 8191702 YP_003067083.1 CDS METDI1496 NC_012988.1 1356761 1357240 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1356761..1357240) Methylobacterium extorquens DM4 8191703 YP_003067084.1 CDS METDI1502 NC_012988.1 1363666 1365759 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Peptidase M23B 1363666..1365759 Methylobacterium extorquens DM4 8196087 YP_003067085.1 CDS METDI1503 NC_012988.1 1365782 1366276 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1365782..1366276) Methylobacterium extorquens DM4 8191705 YP_003067086.1 CDS METDI1504 NC_012988.1 1366361 1367254 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutamyl-tRNA synthetase complement(1366361..1367254) Methylobacterium extorquens DM4 8191706 YP_003067087.1 CDS METDI1505 NC_012988.1 1367285 1367584 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1367285..1367584) Methylobacterium extorquens DM4 8191707 YP_003067088.1 CDS METDI1506 NC_012988.1 1367808 1368026 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1367808..1368026 Methylobacterium extorquens DM4 8191708 YP_003067089.1 CDS htpG NC_012988.1 1368049 1369929 R molecular chaperone; heat shock protein 90 complement(1368049..1369929) Methylobacterium extorquens DM4 8191709 YP_003067090.1 CDS METDI1508 NC_012988.1 1370084 1370275 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1370084..1370275) Methylobacterium extorquens DM4 8195582 YP_003067091.1 CDS METDI1509 NC_012988.1 1370714 1372309 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative gamma-glutamyltranspeptidase 1370714..1372309 Methylobacterium extorquens DM4 8191710 YP_003067092.1 CDS dhaK NC_012988.1 1372412 1374049 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12966101, 7635824; Product type e : enzyme; Dihydroxyacetone kinase (Glycerone kinase) 1372412..1374049 Methylobacterium extorquens DM4 8191711 YP_003067093.1 CDS METDI1511 NC_012988.1 1374058 1374906 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase 1374058..1374906 Methylobacterium extorquens DM4 8195294 YP_003067094.1 CDS oxlT NC_012988.1 1374962 1376254 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; oxalate/formate antiporter 1374962..1376254 Methylobacterium extorquens DM4 8191712 YP_003067095.1 CDS cobL NC_012988.1 1376373 1377608 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1732195, 2211521; Product type e : enzyme; Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] (Precorrin-6 methyltransferase) (Precorrin-6Y methylase) 1376373..1377608 Methylobacterium extorquens DM4 8195816 YP_003067096.1 CDS METDI1514 NC_012988.1 1377587 1378012 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cobalamin biosynthesis protein 1377587..1378012 Methylobacterium extorquens DM4 8195192 YP_003067097.1 CDS METDI1515 NC_012988.1 1378101 1379192 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase; two GGDEF domains 1378101..1379192 Methylobacterium extorquens DM4 8191713 YP_003067098.1 CDS METDI1516 NC_012988.1 1379267 1380175 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator (LysR family) complement(1379267..1380175) Methylobacterium extorquens DM4 8191714 YP_003067099.1 CDS METDI1517 NC_012988.1 1380285 1380728 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1380285..1380728 Methylobacterium extorquens DM4 8191715 YP_003067100.1 CDS cobM NC_012988.1 1380808 1381608 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2211521, 8226690; Product type e : enzyme; Precorrin-4 C(11)-methyltransferase (Precorrin-3 methylase) 1380808..1381608 Methylobacterium extorquens DM4 8191716 YP_003067101.1 CDS cobB NC_012988.1 1381605 1382930 D responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1381605..1382930 Methylobacterium extorquens DM4 8195193 YP_003067102.1 CDS METDI1520 NC_012988.1 1383196 1383624 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, XRE family complement(1383196..1383624) Methylobacterium extorquens DM4 8195182 YP_003067103.1 CDS METDI1521 NC_012988.1 1383830 1384024 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1383830..1384024) Methylobacterium extorquens DM4 8191717 YP_003067104.1 CDS METDI1522 NC_012988.1 1384075 1384410 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1384075..1384410 Methylobacterium extorquens DM4 8191718 YP_003067105.1 CDS fsr NC_012988.1 1384564 1385811 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; multidrug transport protein (MFS family) complement(1384564..1385811) Methylobacterium extorquens DM4 8191719 YP_003067106.1 CDS METDI1524 NC_012988.1 1386242 1387747 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase 1386242..1387747 Methylobacterium extorquens DM4 8195445 YP_003067107.1 CDS METDI1525 NC_012988.1 1387751 1388338 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Fur family; zinc uptake regulator ZUR complement(1387751..1388338) Methylobacterium extorquens DM4 8191720 YP_003067108.1 CDS METDI1526 NC_012988.1 1388685 1389596 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, ATP-binding protein 1388685..1389596 Methylobacterium extorquens DM4 8191721 YP_003067109.1 CDS METDI1527 NC_012988.1 1389650 1390480 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC family transporter permease protein 1389650..1390480 Methylobacterium extorquens DM4 8191722 YP_003067110.1 CDS dnaE NC_012988.1 1391116 1394637 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14762018; Product type e : enzyme; DNA polymerase III, alpha subunit 1391116..1394637 Methylobacterium extorquens DM4 8191723 YP_003067111.1 CDS METDI1529 NC_012988.1 1394959 1395744 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane bound lytic murein transglycosylase B, mltB 1394959..1395744 Methylobacterium extorquens DM4 8195304 YP_003067112.1 CDS METDI1530 NC_012988.1 1395860 1396555 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative cation transport protein (ChaC) complement(1395860..1396555) Methylobacterium extorquens DM4 8191724 YP_003067113.1 CDS METDI1531 NC_012988.1 1396634 1396837 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1396634..1396837) Methylobacterium extorquens DM4 8191725 YP_003067114.1 CDS METDI1532 NC_012988.1 1396800 1397192 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1396800..1397192) Methylobacterium extorquens DM4 8191726 YP_003067115.1 CDS recO NC_012988.1 1397321 1398061 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11743007, 12769856, 1537800, 25401, 94179089, 94266719, 95058623, 98196719; Product type cp : cell process; DNA repair protein RecO 1397321..1398061 Methylobacterium extorquens DM4 8191727 YP_003067116.1 CDS parC NC_012988.1 1398183 1400429 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1398183..1400429 Methylobacterium extorquens DM4 8195973 YP_003067117.1 CDS infA NC_012988.1 1400507 1400764 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1400507..1400764) Methylobacterium extorquens DM4 8195828 YP_003067118.1 CDS METDI1536 NC_012988.1 1401100 1402212 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative extracellular ligand-binding receptor complement(1401100..1402212) Methylobacterium extorquens DM4 8195597 YP_003067119.1 CDS METDI1537 NC_012988.1 1402382 1402705 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1402382..1402705 Methylobacterium extorquens DM4 8191728 YP_003067120.1 CDS METDI1538 NC_012988.1 1402930 1403646 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1402930..1403646 Methylobacterium extorquens DM4 8191729 YP_003067121.1 CDS METDI1539 NC_012988.1 1403651 1404661 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1403651..1404661 Methylobacterium extorquens DM4 8191730 YP_003067122.1 CDS METDI1540 NC_012988.1 1404648 1405241 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1404648..1405241 Methylobacterium extorquens DM4 8191731 YP_003067123.1 CDS METDI1541 NC_012988.1 1405263 1405385 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1405263..1405385) Methylobacterium extorquens DM4 8191732 YP_003067124.1 CDS METDI1542 NC_012988.1 1405631 1406497 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Formyl transferase (fmt-like) complement(1405631..1406497) Methylobacterium extorquens DM4 8191733 YP_003067125.1 CDS METDI1543 NC_012988.1 1406662 1407396 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12524213, 7704278, 9405410; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase 1406662..1407396 Methylobacterium extorquens DM4 8191734 YP_003067126.1 CDS METDI1544 NC_012988.1 1407455 1408216 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1407455..1408216) Methylobacterium extorquens DM4 8191735 YP_003067127.1 CDS METDI1545 NC_012988.1 1408504 1409100 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1408504..1409100 Methylobacterium extorquens DM4 8191736 YP_003067128.1 CDS lolD NC_012988.1 1409305 1410015 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; outer membrane-specific lipoprotein transporter subunit ; ATP-binding component of ABC superfamily complement(1409305..1410015) Methylobacterium extorquens DM4 8191737 YP_003067129.1 CDS METDI1547 NC_012988.1 1410031 1411350 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Lipoprotein releasing system, transmembrane protein, LolC/E family complement(1410031..1411350) Methylobacterium extorquens DM4 8195641 YP_003067130.1 CDS proS NC_012988.1 1411363 1412691 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(1411363..1412691) Methylobacterium extorquens DM4 8191738 YP_003067131.1 CDS METDI1549 NC_012988.1 1413164 1413505 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1413164..1413505) Methylobacterium extorquens DM4 8195904 YP_003067132.1 CDS epi NC_012988.1 1413571 1413975 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 18819910; Product type e : enzyme; ethylmalonyl-CoA/methylmalonyl-CoA epimerase complement(1413571..1413975) Methylobacterium extorquens DM4 8191739 YP_003067133.1 CDS METDI1551 NC_012988.1 1414128 1415801 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase, metallo-beta-lactamase superfamily complement(1414128..1415801) Methylobacterium extorquens DM4 8195331 YP_003067134.1 CDS METDI1552 NC_012988.1 1415821 1416660 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative biotin-protein ligase (birA-like) complement(1415821..1416660) Methylobacterium extorquens DM4 8191740 YP_003067135.1 CDS nuoN NC_012988.1 1416680 1418119 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain N (NADH dehydrogenase I, chain N) complement(1416680..1418119) Methylobacterium extorquens DM4 8191741 YP_003067136.1 CDS nuoM NC_012988.1 1418116 1419699 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain M (NADH dehydrogenase I, chain M) complement(1418116..1419699) Methylobacterium extorquens DM4 8195800 YP_003067137.1 CDS nuoL NC_012988.1 1419699 1421810 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain L (NADH dehydrogenase I, chain L) complement(1419699..1421810) Methylobacterium extorquens DM4 8195799 YP_003067138.1 CDS nuoK NC_012988.1 1421869 1422174 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain K (NADH dehydrogenase I, chain K) complement(1421869..1422174) Methylobacterium extorquens DM4 8195798 YP_003067139.1 CDS nuoJ NC_012988.1 1422180 1422800 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain J (NADH dehydrogenase I, chain J) complement(1422180..1422800) Methylobacterium extorquens DM4 8195797 YP_003067140.1 CDS nuoI NC_012988.1 1423010 1423498 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(1423010..1423498) Methylobacterium extorquens DM4 8195796 YP_003067141.1 CDS nuoH NC_012988.1 1423583 1424605 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(1423583..1424605) Methylobacterium extorquens DM4 8195795 YP_003067142.1 CDS nuoG NC_012988.1 1424618 1426684 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(1424618..1426684) Methylobacterium extorquens DM4 8195794 YP_003067143.1 CDS nuoF NC_012988.1 1426719 1428020 R part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(1426719..1428020) Methylobacterium extorquens DM4 8195793 YP_003067144.1 CDS nuoE NC_012988.1 1428031 1429269 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain E (NADH dehydrogenase I, chain E) complement(1428031..1429269) Methylobacterium extorquens DM4 8195792 YP_003067145.1 CDS nuoD NC_012988.1 1429288 1430478 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain D (NADH dehydrogenase I, chain D) complement(1429288..1430478) Methylobacterium extorquens DM4 8195791 YP_003067146.1 CDS nuoC NC_012988.1 1430490 1431164 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain C (NADH dehydrogenase I, chain C) complement(1430490..1431164) Methylobacterium extorquens DM4 8195790 YP_003067147.1 CDS nuoB NC_012988.1 1431161 1431748 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(1431161..1431748) Methylobacterium extorquens DM4 8195789 YP_003067148.1 CDS nuoA NC_012988.1 1431801 1432166 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH-quinone oxidoreductase chain A (NADH dehydrogenase I, chain A) complement(1431801..1432166) Methylobacterium extorquens DM4 8195788 YP_003067149.1 CDS METDI1567 NC_012988.1 1432998 1433486 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative SCP-like extracellular protein 1432998..1433486 Methylobacterium extorquens DM4 8196222 YP_003067150.1 CDS METDI1568 NC_012988.1 1433532 1433978 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 15299445, 4091802; Product type c : carrier; pseudoazurin complement(1433532..1433978) Methylobacterium extorquens DM4 8191742 YP_003067151.1 CDS carB NC_012988.1 1434273 1437746 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10089390, 9174345; Product type e : enzyme; carbamoyl phosphate synthase, large subunit 1434273..1437746 Methylobacterium extorquens DM4 8191743 YP_003067152.1 CDS greA NC_012988.1 1437877 1438359 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1437877..1438359 Methylobacterium extorquens DM4 8195147 YP_003067153.1 CDS METDI1571 NC_012988.1 1438364 1438864 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1438364..1438864 Methylobacterium extorquens DM4 8195531 YP_003067154.1 CDS METDI1572 NC_012988.1 1438917 1439987 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1438917..1439987 Methylobacterium extorquens DM4 8191744 YP_003067155.1 CDS trxB NC_012988.1 1440138 1441112 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10947986; Product type e : enzyme; thioredoxin reductase, FAD/NAD(P)-binding 1440138..1441112 Methylobacterium extorquens DM4 8191745 YP_003067156.1 CDS METDI1574 NC_012988.1 1441075 1441305 D Evidence 6 : Doubtful CDS; hypothetical protein 1441075..1441305 Methylobacterium extorquens DM4 8196285 YP_003067157.1 CDS METDI1575 NC_012988.1 1441453 1442343 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family 1441453..1442343 Methylobacterium extorquens DM4 8191746 YP_003067158.1 CDS aroQ NC_012988.1 1442460 1442915 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1442460..1442915 Methylobacterium extorquens DM4 8191747 YP_003067159.1 CDS accB NC_012988.1 1442934 1443404 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10542197; Product type c : carrier; acetyl-CoA carboxylase, biotin carboxyl carrier protein subunit 1442934..1443404 Methylobacterium extorquens DM4 8195095 YP_003067160.1 CDS accC NC_012988.1 1443415 1444782 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10821865, 7915138; Product type e : enzyme; acetyl CoA carboxylase, biotin carboxylase subunit 1443415..1444782 Methylobacterium extorquens DM4 8195045 YP_003067161.1 CDS aat NC_012988.1 1444834 1445541 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 90352297, 91177849; Product type pe : putative enzyme; putative leucyl/phenylalanyl-tRNA-protein transferase 1444834..1445541 Methylobacterium extorquens DM4 8195046 YP_003067162.1 CDS METDI1580 NC_012988.1 1445607 1446227 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, TetR family complement(1445607..1446227) Methylobacterium extorquens DM4 8195042 YP_003067163.1 CDS METDI1581 NC_012988.1 1446275 1446754 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1446275..1446754 Methylobacterium extorquens DM4 8191748 YP_003067164.1 CDS METDI1582 NC_012988.1 1446824 1447483 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1446824..1447483) Methylobacterium extorquens DM4 8191749 YP_003067165.1 CDS METDI1584 NC_012988.1 1447661 1448077 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH:ubiquinone oxidoreductase 17.2 kD subunit complement(1447661..1448077) Methylobacterium extorquens DM4 8191750 YP_003067166.1 CDS nrd NC_012988.1 1448597 1452328 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1448597..1452328 Methylobacterium extorquens DM4 8191751 YP_003067167.1 CDS METDI1586 NC_012988.1 1452662 1455646 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enzyme with a helicase domain 1452662..1455646 Methylobacterium extorquens DM4 8195778 YP_003067168.1 CDS METDI1587 NC_012988.1 1455827 1457476 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex10, ISL3 family complement(1455827..1457476) Methylobacterium extorquens DM4 8191752 YP_003067169.1 CDS METDI1588 NC_012988.1 1457641 1457886 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex5, IS3 family (ORF 1) 1457641..1457886 Methylobacterium extorquens DM4 8191753 YP_003067170.1 CDS METDI1592 NC_012988.1 1460866 1461132 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex11, IS3 family (ORF 1) 1460866..1461132 Methylobacterium extorquens DM4 8191757 YP_003067171.1 CDS METDI1593 NC_012988.1 1461129 1461965 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex11, IS3 family (ORF 2) 1461129..1461965 Methylobacterium extorquens DM4 8191758 YP_003067172.1 CDS METDI1594 NC_012988.1 1462268 1463398 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Arylamine N-acetyltransferase complement(1462268..1463398) Methylobacterium extorquens DM4 8191759 YP_003067173.1 CDS METDI1595 NC_012988.1 1463827 1464309 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1463827..1464309) Methylobacterium extorquens DM4 8191760 YP_003067174.1 CDS METDI1596 NC_012988.1 1464495 1464791 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1464495..1464791 Methylobacterium extorquens DM4 8191761 YP_003067175.1 CDS METDI1597 NC_012988.1 1464921 1465256 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1464921..1465256 Methylobacterium extorquens DM4 8191762 YP_003067176.1 CDS METDI1598 NC_012988.1 1465357 1465587 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1465357..1465587 Methylobacterium extorquens DM4 8191763 YP_003067177.1 CDS METDI1599 NC_012988.1 1465512 1465847 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1465512..1465847 Methylobacterium extorquens DM4 8191764 YP_003067178.1 CDS METDI1600 NC_012988.1 1465817 1466194 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1465817..1466194 Methylobacterium extorquens DM4 8191765 YP_003067179.1 CDS METDI1601 NC_012988.1 1466239 1467099 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR complement(1466239..1467099) Methylobacterium extorquens DM4 8191766 YP_003067180.1 CDS METDI1602 NC_012988.1 1467110 1468039 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 1467110..1468039 Methylobacterium extorquens DM4 8191767 YP_003067181.1 CDS ftsH NC_012988.1 1468331 1470193 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6389496, 92065796, 93186701, 94068502, 94148987, 9636708, 9643547, 9712851; Product type e : enzyme; protease, ATP-dependent zinc-metallo 1468331..1470193 Methylobacterium extorquens DM4 8191768 YP_003067182.1 CDS METDI1604 NC_012988.1 1470305 1470736 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1470305..1470736) Methylobacterium extorquens DM4 8195450 YP_003067183.1 CDS METDI1605 NC_012988.1 1471213 1471473 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1471213..1471473 Methylobacterium extorquens DM4 8191769 YP_003067184.1 CDS METDI1606 NC_012988.1 1471612 1472730 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallopeptidase, CBS (cystathionine-beta-synthase)domain complement(1471612..1472730) Methylobacterium extorquens DM4 8191770 YP_003067185.1 CDS METDI1607 NC_012988.1 1473246 1473431 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1473246..1473431 Methylobacterium extorquens DM4 8191771 YP_003067186.1 CDS lon NC_012988.1 1473500 1475911 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8331082, 8331083; Product type e : enzyme; DNA-binding ATP-dependent protease La, induced by heat shock and other stresses complement(1473500..1475911) Methylobacterium extorquens DM4 8191772 YP_003067187.1 CDS METDI1609 NC_012988.1 1475925 1476332 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative small heat shock protein (HSP20) family complement(1475925..1476332) Methylobacterium extorquens DM4 8195642 YP_003067188.1 CDS METDI1610 NC_012988.1 1476436 1476639 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1476436..1476639) Methylobacterium extorquens DM4 8191773 YP_003067189.1 CDS METDI1611 NC_012988.1 1476714 1477625 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275; Product type e : enzyme; Molecular chaperone dnaJ family complement(1476714..1477625) Methylobacterium extorquens DM4 8191774 YP_003067190.1 CDS METDI1612 NC_012988.1 1477976 1478413 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1477976..1478413) Methylobacterium extorquens DM4 8191775 YP_003067191.1 CDS MEDTI5947 NC_012988.1 1478467 1479108 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1478467..1479108) Methylobacterium extorquens DM4 8191776 YP_003067192.1 CDS METDI1613 NC_012988.1 1479132 1479560 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1479132..1479560) Methylobacterium extorquens DM4 8190529 YP_003067193.1 CDS METDI1614 NC_012988.1 1479931 1480299 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1479931..1480299) Methylobacterium extorquens DM4 8191777 YP_003067194.1 CDS METDI1615 NC_012988.1 1480304 1480801 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; small heat shock protein complement(1480304..1480801) Methylobacterium extorquens DM4 8191778 YP_003067195.1 CDS METDI1616 NC_012988.1 1481130 1481411 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1481130..1481411) Methylobacterium extorquens DM4 8191779 YP_003067196.1 CDS glgX NC_012988.1 1481936 1484212 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glycogen debranching enzyme complement(1481936..1484212) Methylobacterium extorquens DM4 8191780 YP_003067197.1 CDS METDI1618 NC_012988.1 1484434 1484748 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1484434..1484748 Methylobacterium extorquens DM4 8195491 YP_003067198.1 CDS METDI1619 NC_012988.1 1485056 1485283 D Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein 1485056..1485283 Methylobacterium extorquens DM4 8191781 YP_003067199.1 CDS METDI1620 NC_012988.1 1485445 1485615 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1485445..1485615 Methylobacterium extorquens DM4 8191782 YP_003067200.1 CDS METDI1621 NC_012988.1 1485858 1486109 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1485858..1486109) Methylobacterium extorquens DM4 8191783 YP_003067201.1 CDS METDI1622 NC_012988.1 1486420 1486632 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1486420..1486632) Methylobacterium extorquens DM4 8191784 YP_003067202.1 CDS METDI1623 NC_012988.1 1487067 1487522 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1487067..1487522) Methylobacterium extorquens DM4 8191785 YP_003067203.1 CDS METDI1624 NC_012988.1 1487922 1488152 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1487922..1488152 Methylobacterium extorquens DM4 8191786 YP_003067204.1 CDS METDI1626 NC_012988.1 1488846 1489277 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1488846..1489277 Methylobacterium extorquens DM4 8191788 YP_003067205.1 CDS clpB NC_012988.1 1490424 1493048 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; protein disaggregation chaperone complement(1490424..1493048) Methylobacterium extorquens DM4 8191790 YP_003067206.1 CDS METDI1629 NC_012988.1 1493218 1494438 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; signal transduction histidine kinase; GAF domain complement(1493218..1494438) Methylobacterium extorquens DM4 8195170 YP_003067207.1 CDS trx NC_012988.1 1494671 1495084 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9388228; Product type c : carrier; thioredoxin 1494671..1495084 Methylobacterium extorquens DM4 8191791 YP_003067208.1 CDS METDI1631 NC_012988.1 1495231 1495563 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1495231..1495563) Methylobacterium extorquens DM4 8196282 YP_003067209.1 CDS METDI1632 NC_012988.1 1496167 1496925 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1496167..1496925) Methylobacterium extorquens DM4 8191792 YP_003067210.1 CDS METDI1633 NC_012988.1 1497360 1497872 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative molecular chaperone, heat shock Hsp20 family complement(1497360..1497872) Methylobacterium extorquens DM4 8191793 YP_003067211.1 CDS ibpA NC_012988.1 1497968 1498465 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; small heat shock protein complement(1497968..1498465) Methylobacterium extorquens DM4 8191794 YP_003067212.1 CDS METDI1635 NC_012988.1 1498818 1500236 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phospholipase D/transphosphatidylase complement(1498818..1500236) Methylobacterium extorquens DM4 8195584 YP_003067213.1 CDS METDI1636 NC_012988.1 1501348 1501845 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; small heat shock protein 1501348..1501845 Methylobacterium extorquens DM4 8191795 YP_003067214.1 CDS METDI1637 NC_012988.1 1501903 1502460 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative molecular chaperone, heat shock Hsp20 family 1501903..1502460 Methylobacterium extorquens DM4 8191796 YP_003067215.1 CDS METDI1638 NC_012988.1 1502560 1502976 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1502560..1502976) Methylobacterium extorquens DM4 8191797 YP_003067216.1 CDS METDI1639 NC_012988.1 1503041 1503340 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1503041..1503340 Methylobacterium extorquens DM4 8191798 YP_003067217.1 CDS METDI1640 NC_012988.1 1503367 1504119 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1503367..1504119 Methylobacterium extorquens DM4 8191799 YP_003067218.1 CDS METDI1641 NC_012988.1 1504262 1504666 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1504262..1504666 Methylobacterium extorquens DM4 8191800 YP_003067219.1 CDS METDI1642 NC_012988.1 1504960 1505970 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10920254, 11160799, 7651136, 8407802; Product type pm : putative membrane component; RND efflux transporter, membrane fusion protein subunit 1504960..1505970 Methylobacterium extorquens DM4 8191801 YP_003067220.1 CDS METDI1643 NC_012988.1 1506209 1506769 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1506209..1506769 Methylobacterium extorquens DM4 8191802 YP_003067221.1 CDS METDI1644 NC_012988.1 1506877 1507176 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1506877..1507176 Methylobacterium extorquens DM4 8191803 YP_003067222.1 CDS METDI1645 NC_012988.1 1507388 1507717 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1507388..1507717) Methylobacterium extorquens DM4 8191804 YP_003067223.1 CDS METDI1646 NC_012988.1 1507861 1508112 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1507861..1508112 Methylobacterium extorquens DM4 8191805 YP_003067224.1 CDS METDI1647 NC_012988.1 1508287 1510446 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1508287..1510446 Methylobacterium extorquens DM4 8191806 YP_003067225.1 CDS METDI1648 NC_012988.1 1510446 1510640 D Evidence 6 : Doubtful CDS; hypothetical protein 1510446..1510640 Methylobacterium extorquens DM4 8191807 YP_003067226.1 CDS METDI1649 NC_012988.1 1511291 1511611 D Evidence 6 : Doubtful CDS; hypothetical protein 1511291..1511611 Methylobacterium extorquens DM4 8191808 YP_003067227.1 CDS METDI1650 NC_012988.1 1512111 1512578 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1512111..1512578 Methylobacterium extorquens DM4 8191809 YP_003067228.1 CDS METDI1651 NC_012988.1 1513315 1514073 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1513315..1514073 Methylobacterium extorquens DM4 8191810 YP_003067229.1 CDS METDI1652 NC_012988.1 1514073 1516442 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1514073..1516442 Methylobacterium extorquens DM4 8191811 YP_003067230.1 CDS METDI1653 NC_012988.1 1516384 1517667 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1516384..1517667 Methylobacterium extorquens DM4 8191812 YP_003067231.1 CDS METDI1654 NC_012988.1 1517664 1519508 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1517664..1519508 Methylobacterium extorquens DM4 8191813 YP_003067232.1 CDS METDI1657 NC_012988.1 1520589 1520795 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1520589..1520795 Methylobacterium extorquens DM4 8191816 YP_003067233.1 CDS METDI1658 NC_012988.1 1523061 1523810 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ion transporter 1523061..1523810 Methylobacterium extorquens DM4 8191817 YP_003067234.1 CDS METDI1659 NC_012988.1 1523893 1524705 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1523893..1524705) Methylobacterium extorquens DM4 8191818 YP_003067235.1 CDS METDI1660 NC_012988.1 1524814 1525389 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 1524814..1525389 Methylobacterium extorquens DM4 8191819 YP_003067236.1 CDS METDI1661 NC_012988.1 1525744 1526130 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10368157; Product type pr : putative regulator; putative translational regulator (YjgH-related) complement(1525744..1526130) Methylobacterium extorquens DM4 8191820 YP_003067237.1 CDS METDI1662 NC_012988.1 1526229 1527239 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADH:flavin oxidoreductase/NADH oxidase complement(1526229..1527239) Methylobacterium extorquens DM4 8191821 YP_003067238.1 CDS METDI1663 NC_012988.1 1527435 1528358 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, LysR family 1527435..1528358 Methylobacterium extorquens DM4 8191822 YP_003067239.1 CDS METDI1664 NC_012988.1 1528636 1529220 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1528636..1529220 Methylobacterium extorquens DM4 8191823 YP_003067240.1 CDS METDI1665 NC_012988.1 1530039 1530566 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1530039..1530566 Methylobacterium extorquens DM4 8191824 YP_003067241.1 CDS METDI1666 NC_012988.1 1531517 1532392 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8763943; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(1531517..1532392) Methylobacterium extorquens DM4 8191825 YP_003067242.1 CDS METDI1667 NC_012988.1 1532536 1533492 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, periplasmic protein; putative taurine transporter 1532536..1533492 Methylobacterium extorquens DM4 8191826 YP_003067243.1 CDS METDI1668 NC_012988.1 1533600 1534370 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, permease component; putative taurine transporter 1533600..1534370 Methylobacterium extorquens DM4 8191827 YP_003067244.1 CDS METDI1669 NC_012988.1 1534363 1535142 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, ATPase; putative taurine transporter 1534363..1535142 Methylobacterium extorquens DM4 8191828 YP_003067245.1 CDS METDI1670 NC_012988.1 1535142 1535972 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1535142..1535972 Methylobacterium extorquens DM4 8191829 YP_003067246.1 CDS METDI1671 NC_012988.1 1535996 1537846 D catalyzes the hydrolysis of allophanate; allophanate hydrolase 1535996..1537846 Methylobacterium extorquens DM4 8191830 YP_003067247.1 CDS METDI1672 NC_012988.1 1538105 1539148 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1538105..1539148) Methylobacterium extorquens DM4 8191831 YP_003067248.1 CDS METDI1673 NC_012988.1 1539359 1540411 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1539359..1540411 Methylobacterium extorquens DM4 8191832 YP_003067249.1 CDS METDI1674 NC_012988.1 1540436 1540609 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1540436..1540609) Methylobacterium extorquens DM4 8191833 YP_003067250.1 CDS METDI1675 NC_012988.1 1540587 1542119 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase of the HWE family complement(1540587..1542119) Methylobacterium extorquens DM4 8191834 YP_003067251.1 CDS METDI1676 NC_012988.1 1542394 1543059 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR complement(1542394..1543059) Methylobacterium extorquens DM4 8191835 YP_003067252.1 CDS METDI1677 NC_012988.1 1543119 1543754 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1543119..1543754) Methylobacterium extorquens DM4 8191836 YP_003067253.1 CDS METDI1678 NC_012988.1 1544026 1544679 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1544026..1544679) Methylobacterium extorquens DM4 8191837 YP_003067254.1 CDS METDI1679 NC_012988.1 1544612 1544815 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1544612..1544815) Methylobacterium extorquens DM4 8191838 YP_003067255.1 CDS METDI1680 NC_012988.1 1544970 1545344 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1544970..1545344 Methylobacterium extorquens DM4 8191839 YP_003067256.1 CDS trkD NC_012988.1 1545446 1547356 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 89197799, 94042856, 99229748; Product type t : transporter; potassium uptake protein Kup 1545446..1547356 Methylobacterium extorquens DM4 8191840 YP_003067257.1 CDS METDI1682 NC_012988.1 1547415 1547876 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1547415..1547876) Methylobacterium extorquens DM4 8196208 YP_003067258.1 CDS METDI1683 NC_012988.1 1547972 1548181 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1547972..1548181) Methylobacterium extorquens DM4 8191841 YP_003067259.1 CDS METDI1684 NC_012988.1 1548242 1549195 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1548242..1549195) Methylobacterium extorquens DM4 8191842 YP_003067260.1 CDS METDI1685 NC_012988.1 1549480 1549722 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1549480..1549722) Methylobacterium extorquens DM4 8191843 YP_003067261.1 CDS METDI1686 NC_012988.1 1550052 1551104 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1550052..1551104 Methylobacterium extorquens DM4 8191844 YP_003067262.1 CDS METDI1687 NC_012988.1 1551139 1552272 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Metallophosphoesterase 1551139..1552272 Methylobacterium extorquens DM4 8191845 YP_003067263.1 CDS METDI1688 NC_012988.1 1552673 1552933 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1552673..1552933) Methylobacterium extorquens DM4 8191846 YP_003067264.1 CDS METDI1689 NC_012988.1 1552981 1553538 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1552981..1553538) Methylobacterium extorquens DM4 8191847 YP_003067265.1 CDS METDI1690 NC_012988.1 1553857 1554354 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1553857..1554354) Methylobacterium extorquens DM4 8191848 YP_003067266.1 CDS METDI1691 NC_012988.1 1554723 1556207 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1554723..1556207) Methylobacterium extorquens DM4 8191849 YP_003067267.1 CDS METDI1692 NC_012988.1 1556327 1556569 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1556327..1556569) Methylobacterium extorquens DM4 8191850 YP_003067268.1 CDS METDI1693 NC_012988.1 1556837 1557025 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1556837..1557025) Methylobacterium extorquens DM4 8191851 YP_003067269.1 CDS METDI1694 NC_012988.1 1557211 1557396 D Evidence 6 : Doubtful CDS; hypothetical protein 1557211..1557396 Methylobacterium extorquens DM4 8191852 YP_003067270.1 CDS METDI1695 NC_012988.1 1558203 1558742 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1558203..1558742 Methylobacterium extorquens DM4 8191853 YP_003067271.1 CDS METDI1696 NC_012988.1 1558825 1559607 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi18, IS1595 family complement(1558825..1559607) Methylobacterium extorquens DM4 8191854 YP_003067272.1 CDS METDI1697 NC_012988.1 1560162 1561001 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative formate/nitrate transporter 1560162..1561001 Methylobacterium extorquens DM4 8191855 YP_003067273.1 CDS METDI1698 NC_012988.1 1561069 1562784 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dual serine/threonine-protein kinase/phosphatase 1561069..1562784 Methylobacterium extorquens DM4 8191856 YP_003067274.1 CDS METDI1699 NC_012988.1 1563855 1565873 R [UDP-forming]; Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Cellulose synthase catalytic subunit complement(1563855..1565873) Methylobacterium extorquens DM4 8191857 YP_003067275.1 CDS METDI1700 NC_012988.1 1565855 1567021 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Multidrug resistance efflux pump complement(1565855..1567021) Methylobacterium extorquens DM4 8191858 YP_003067276.1 CDS METDI1701 NC_012988.1 1568185 1568574 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1568185..1568574) Methylobacterium extorquens DM4 8191859 YP_003067277.1 CDS METDI1702 NC_012988.1 1568663 1568908 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1568663..1568908 Methylobacterium extorquens DM4 8191860 YP_003067278.1 CDS METDI1703 NC_012988.1 1568869 1569255 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1568869..1569255 Methylobacterium extorquens DM4 8191861 YP_003067279.1 CDS METDI1706 NC_012988.1 1570387 1571139 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) complement(1570387..1571139) Methylobacterium extorquens DM4 8191864 YP_003067280.1 CDS METDI1707 NC_012988.1 1571247 1571528 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) complement(1571247..1571528) Methylobacterium extorquens DM4 8191865 YP_003067281.1 CDS METDI1708 NC_012988.1 1571607 1572410 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1571607..1572410 Methylobacterium extorquens DM4 8191866 YP_003067282.1 CDS METDI1709 NC_012988.1 1572427 1572921 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1572427..1572921 Methylobacterium extorquens DM4 8191867 YP_003067283.1 CDS METDI1710 NC_012988.1 1572935 1573120 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1572935..1573120) Methylobacterium extorquens DM4 8191868 YP_003067284.1 CDS METDI1711 NC_012988.1 1573298 1574140 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1573298..1574140) Methylobacterium extorquens DM4 8191869 YP_003067285.1 CDS acrF NC_012988.1 1574182 1577373 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; multidrug transport protein, acriflavin resistance protein F (RND family) complement(1574182..1577373) Methylobacterium extorquens DM4 8191870 YP_003067286.1 CDS METDI1713 NC_012988.1 1577379 1578503 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative RND efflux transporter, membrane fusion protein subunit complement(1577379..1578503) Methylobacterium extorquens DM4 8195055 YP_003067287.1 CDS METDI1714 NC_012988.1 1578760 1579014 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1578760..1579014) Methylobacterium extorquens DM4 8191871 YP_003067288.1 CDS METDI1715 NC_012988.1 1578962 1579411 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1578962..1579411) Methylobacterium extorquens DM4 8191872 YP_003067289.1 CDS METDI1716 NC_012988.1 1579415 1579840 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(1579415..1579840) Methylobacterium extorquens DM4 8191873 YP_003067290.1 CDS METDI1717 NC_012988.1 1580260 1582200 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase 1580260..1582200 Methylobacterium extorquens DM4 8191874 YP_003067291.1 CDS METDI1718 NC_012988.1 1582308 1582631 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12151239, 12426355, 1840615; Product type r : regulator; transcriptional regulator, ArsR family complement(1582308..1582631) Methylobacterium extorquens DM4 8191875 YP_003067292.1 CDS nrtC NC_012988.1 1583060 1584040 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; nitrate transport system ATP-binding protein complement(1583060..1584040) Methylobacterium extorquens DM4 8191876 YP_003067293.1 CDS nrtB NC_012988.1 1584049 1584903 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; nitrate transport system permease protein complement(1584049..1584903) Methylobacterium extorquens DM4 8195783 YP_003067294.1 CDS nrtA NC_012988.1 1584893 1586254 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; nitrate ABC transporter component precursor (substrate-binding protein) (tat pathway signal) complement(1584893..1586254) Methylobacterium extorquens DM4 8195781 YP_003067295.1 CDS METDI1722 NC_012988.1 1586420 1587754 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; FAD-dependent pyridine nucleotide-disulphide oxidoreductase:Rubredoxin-type Fe(Cys)4 protein complement(1586420..1587754) Methylobacterium extorquens DM4 8195779 YP_003067296.1 CDS METDI1723 NC_012988.1 1587751 1588944 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyl-CoA dehydrogenase complement(1587751..1588944) Methylobacterium extorquens DM4 8191877 YP_003067297.1 CDS METDI1724 NC_012988.1 1589005 1589556 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; OsmC family protein (osmotically induced proteins) complement(1589005..1589556) Methylobacterium extorquens DM4 8191878 YP_003067298.1 CDS METDI1725 NC_012988.1 1589769 1591373 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2450865, 2840552; Product type pr : putative regulator; putative two-component sigma-54 specific transcriptional regulator, Fis subfamily; with N-terminal response receiver, GAF and ATPase domains complement(1589769..1591373) Methylobacterium extorquens DM4 8191879 YP_003067299.1 CDS METDI1726 NC_012988.1 1591743 1592717 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative bifunctional protein; N-terminal amidase, C-terminal transcriptional regulator, AraC family complement(1591743..1592717) Methylobacterium extorquens DM4 8191880 YP_003067300.1 CDS inh NC_012988.1 1592810 1593514 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12244065; Product type e : enzyme; isonitrile hydratase, ThiJ/PfpI family protein 1592810..1593514 Methylobacterium extorquens DM4 8191881 YP_003067301.1 CDS METDI1728 NC_012988.1 1593589 1595157 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium:solute symporter complement(1593589..1595157) Methylobacterium extorquens DM4 8195600 YP_003067302.1 CDS METDI1729 NC_012988.1 1595168 1595389 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1595168..1595389) Methylobacterium extorquens DM4 8191882 YP_003067303.1 CDS METDI1730 NC_012988.1 1595573 1596682 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nitrilase complement(1595573..1596682) Methylobacterium extorquens DM4 8191883 YP_003067304.1 CDS METDI1731 NC_012988.1 1596785 1597681 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family complement(1596785..1597681) Methylobacterium extorquens DM4 8191884 YP_003067305.1 CDS METDI1734 NC_012988.1 1598497 1599051 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor 1598497..1599051 Methylobacterium extorquens DM4 8191885 YP_003067306.1 CDS METDI1736 NC_012988.1 1599537 1599833 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, Cro/CI family complement(1599537..1599833) Methylobacterium extorquens DM4 8191886 YP_003067307.1 CDS METDI1737 NC_012988.1 1600193 1601956 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; type I secretion system ATPase 1600193..1601956 Methylobacterium extorquens DM4 8191887 YP_003067308.1 CDS METDI1738 NC_012988.1 1601966 1603342 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; type I secretion membrane fusion protein, HlyD family 1601966..1603342 Methylobacterium extorquens DM4 8191888 YP_003067309.1 CDS METDI1739 NC_012988.1 1603421 1607839 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1603421..1607839 Methylobacterium extorquens DM4 8191889 YP_003067310.1 CDS METDI1740 NC_012988.1 1607978 1609933 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative Cellulose synthase (UDP-forming) complement(1607978..1609933) Methylobacterium extorquens DM4 8191890 YP_003067311.1 CDS METDI1741 NC_012988.1 1609933 1611108 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1609933..1611108) Methylobacterium extorquens DM4 8191891 YP_003067312.1 CDS METDI1742 NC_012988.1 1611144 1612898 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1611144..1612898) Methylobacterium extorquens DM4 8191892 YP_003067313.1 CDS METDI1743 NC_012988.1 1614054 1614854 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10913158; Product type t : transporter; ABC transporter, ATPase complement(1614054..1614854) Methylobacterium extorquens DM4 8191893 YP_003067314.1 CDS METDI1744 NC_012988.1 1614848 1615846 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, permease complement(1614848..1615846) Methylobacterium extorquens DM4 8191894 YP_003067315.1 CDS METDI1745 NC_012988.1 1615856 1616941 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, periplasmic protein complement(1615856..1616941) Methylobacterium extorquens DM4 8191895 YP_003067316.1 CDS METDI1746 NC_012988.1 1617479 1618624 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Acyl-CoA dehydrogenase 1617479..1618624 Methylobacterium extorquens DM4 8191896 YP_003067317.1 CDS METDI1747 NC_012988.1 1618643 1619740 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10506196; Product type pe : putative enzyme; putative alkanesulfonate monooxygenase 1618643..1619740 Methylobacterium extorquens DM4 8191897 YP_003067318.1 CDS ssuA NC_012988.1 1619740 1620681 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, substrate-binding protein, aliphatic sulphonates 1619740..1620681 Methylobacterium extorquens DM4 8191898 YP_003067319.1 CDS METDI1749 NC_012988.1 1620708 1621250 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mannose-6-phosphate isomerase 1620708..1621250 Methylobacterium extorquens DM4 8196149 YP_003067320.1 CDS METDI1751 NC_012988.1 1621900 1622103 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1621900..1622103 Methylobacterium extorquens DM4 8191899 YP_003067321.1 CDS cysE-2 NC_012988.1 1622189 1623034 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10617639, 3309158; Product type e : enzyme; serine acetyltransferase 1622189..1623034 Methylobacterium extorquens DM4 8191900 YP_003067322.1 CDS eshA NC_012988.1 1623455 1624846 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11325927, 11567001, 12488450, 16788203, 16926146; Product type e : enzyme; eshA 1623455..1624846 Methylobacterium extorquens DM4 8195252 YP_003067323.1 CDS METDI1754 NC_012988.1 1624833 1626857 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cysteine desulfurase 1624833..1626857 Methylobacterium extorquens DM4 8195333 YP_003067324.1 CDS METDI1755 NC_012988.1 1626932 1627516 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1626932..1627516) Methylobacterium extorquens DM4 8191901 YP_003067325.1 CDS METDI1759 NC_012988.1 1629180 1630157 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Thioredoxin reductase 1629180..1630157 Methylobacterium extorquens DM4 8191903 YP_003067326.1 CDS METDI1760 NC_012988.1 1630385 1631254 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer-membrane immunogenic protein precursor 1630385..1631254 Methylobacterium extorquens DM4 8191904 YP_003067327.1 CDS METDI1761 NC_012988.1 1631643 1631894 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1631643..1631894 Methylobacterium extorquens DM4 8191905 YP_003067328.1 CDS METDI1762 NC_012988.1 1631906 1632319 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1631906..1632319 Methylobacterium extorquens DM4 8191906 YP_003067329.1 CDS cspA NC_012988.1 1633662 1633871 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10483731, 10618253; Product type f : factor; cold shock DNA binding protein CspA 1633662..1633871 Methylobacterium extorquens DM4 8191907 YP_003067330.1 CDS METDI1764 NC_012988.1 1634079 1634324 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1634079..1634324 Methylobacterium extorquens DM4 8195223 YP_003067331.1 CDS METDI1765 NC_012988.1 1634547 1634879 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1634547..1634879) Methylobacterium extorquens DM4 8191908 YP_003067332.1 CDS METDI1766 NC_012988.1 1635234 1637192 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1635234..1637192 Methylobacterium extorquens DM4 8191909 YP_003067333.1 CDS METDI1767 NC_012988.1 1637364 1638095 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1637364..1638095) Methylobacterium extorquens DM4 8191910 YP_003067334.1 CDS METDI1768 NC_012988.1 1638507 1641503 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase of the HWE family complement(1638507..1641503) Methylobacterium extorquens DM4 8191911 YP_003067335.1 CDS METDI1769 NC_012988.1 1641738 1642412 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1641738..1642412) Methylobacterium extorquens DM4 8191912 YP_003067336.1 CDS METDI1770 NC_012988.1 1642850 1644817 D in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 1642850..1644817 Methylobacterium extorquens DM4 8191913 YP_003067337.1 CDS METDI1771 NC_012988.1 1645080 1646123 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1645080..1646123 Methylobacterium extorquens DM4 8191914 YP_003067338.1 CDS ureE NC_012988.1 1646407 1646871 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1646407..1646871 Methylobacterium extorquens DM4 8191915 YP_003067339.1 CDS METDI1774 NC_012988.1 1646876 1647556 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f : factor; putative urease accessory protein UreF 1646876..1647556 Methylobacterium extorquens DM4 8191916 YP_003067340.1 CDS ureAB NC_012988.1 1647570 1648265 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; bifunctional urease subunit gamma/beta 1647570..1648265 Methylobacterium extorquens DM4 8191917 YP_003067341.1 CDS ureC NC_012988.1 1648281 1649993 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1648281..1649993 Methylobacterium extorquens DM4 8196309 YP_003067342.1 CDS ureG NC_012988.1 1649990 1650634 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8045421; Product type e : enzyme; urease accessory protein UreG 1649990..1650634 Methylobacterium extorquens DM4 8196313 YP_003067343.1 CDS METDI1778 NC_012988.1 1650634 1651518 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7813887; Product type f : factor; putative urease accessory protein UreD 1650634..1651518 Methylobacterium extorquens DM4 8196325 YP_003067344.1 CDS fmdD NC_012988.1 1651708 1652949 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9245819, 9492267; Product type f : factor; short-chain amide-urea binding porin 1651708..1652949 Methylobacterium extorquens DM4 8191918 YP_003067345.1 CDS METDI1780 NC_012988.1 1652965 1654161 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1652965..1654161) Methylobacterium extorquens DM4 8195433 YP_003067346.1 CDS METDI1781 NC_012988.1 1654161 1656362 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent porin receptor complement(1654161..1656362) Methylobacterium extorquens DM4 8191919 YP_003067347.1 CDS METDI1782 NC_012988.1 1657112 1658302 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1657112..1658302 Methylobacterium extorquens DM4 8195033 YP_003067348.1 CDS METDI1783 NC_012988.1 1658426 1658794 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1658426..1658794) Methylobacterium extorquens DM4 8191921 YP_003067349.1 CDS METDI1784 NC_012988.1 1658827 1659270 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1658827..1659270) Methylobacterium extorquens DM4 8191922 YP_003067350.1 CDS METDI1785 NC_012988.1 1659336 1659512 D Evidence 6 : Doubtful CDS; hypothetical protein 1659336..1659512 Methylobacterium extorquens DM4 8191923 YP_003067351.1 CDS METDI1786 NC_012988.1 1659537 1659986 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1659537..1659986 Methylobacterium extorquens DM4 8191924 YP_003067352.1 CDS frc NC_012988.1 1660087 1661337 D catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 1660087..1661337 Methylobacterium extorquens DM4 8191925 YP_003067353.1 CDS METDI1788 NC_012988.1 1661577 1662296 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phospholipase/Carboxylesterase complement(1661577..1662296) Methylobacterium extorquens DM4 8195442 YP_003067354.1 CDS METDI1789 NC_012988.1 1662560 1664311 R catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase complement(1662560..1664311) Methylobacterium extorquens DM4 8191926 YP_003067355.1 CDS METDI1790 NC_012988.1 1664788 1667079 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Galactose oxidase complement(1664788..1667079) Methylobacterium extorquens DM4 8191927 YP_003067356.1 CDS oxlT NC_012988.1 1667432 1668757 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; oxalate/formate antiporter complement(1667432..1668757) Methylobacterium extorquens DM4 8191928 YP_003067357.1 CDS oxlT NC_012988.1 1669022 1670278 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; oxalate/formate antiporter complement(1669022..1670278) Methylobacterium extorquens DM4 8195817 YP_003067358.1 CDS METDI1793 NC_012988.1 1670783 1670956 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1670783..1670956) Methylobacterium extorquens DM4 8195818 YP_003067359.1 CDS METDI1794 NC_012988.1 1670873 1671313 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1670873..1671313 Methylobacterium extorquens DM4 8191929 YP_003067360.1 CDS METDI1795 NC_012988.1 1671480 1671761 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1671480..1671761 Methylobacterium extorquens DM4 8191930 YP_003067361.1 CDS METDI1796 NC_012988.1 1671784 1673640 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1671784..1673640 Methylobacterium extorquens DM4 8191931 YP_003067362.1 CDS METDI1797 NC_012988.1 1673653 1673838 D Evidence 6 : Doubtful CDS; hypothetical protein 1673653..1673838 Methylobacterium extorquens DM4 8191932 YP_003067363.1 CDS METDI1798 NC_012988.1 1673860 1674027 D Evidence 6 : Doubtful CDS; hypothetical protein 1673860..1674027 Methylobacterium extorquens DM4 8191933 YP_003067364.1 CDS METDI1799 NC_012988.1 1674009 1674236 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1674009..1674236) Methylobacterium extorquens DM4 8191934 YP_003067365.1 CDS frc NC_012988.1 1674375 1675664 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12844490; Product type e : enzyme; formyl-CoA transferase, NAD(P)-binding complement(1674375..1675664) Methylobacterium extorquens DM4 8191935 YP_003067366.1 CDS METDI1801 NC_012988.1 1676085 1676768 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, GntR family 1676085..1676768 Methylobacterium extorquens DM4 8195443 YP_003067367.1 CDS METDI1802 NC_012988.1 1676900 1678000 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative GTPase, putative cobalamin biosynthesis protein (CobW homolog) complement(1676900..1678000) Methylobacterium extorquens DM4 8191936 YP_003067368.1 CDS METDI1803 NC_012988.1 1678132 1679637 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; serine-type D-alanyl-D-alanine carboxypeptidase precursor complement(1678132..1679637) Methylobacterium extorquens DM4 8191937 YP_003067369.1 CDS METDI1804 NC_012988.1 1679909 1680547 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1679909..1680547 Methylobacterium extorquens DM4 8191938 YP_003067370.1 CDS METDI1805 NC_012988.1 1680711 1681148 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1680711..1681148 Methylobacterium extorquens DM4 8191939 YP_003067371.1 CDS METDI1806 NC_012988.1 1681241 1681525 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1681241..1681525 Methylobacterium extorquens DM4 8191940 YP_003067372.1 CDS METDI1807 NC_012988.1 1681619 1682860 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydroxylase complement(1681619..1682860) Methylobacterium extorquens DM4 8191941 YP_003067373.1 CDS METDI1808 NC_012988.1 1683146 1683583 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1683146..1683583) Methylobacterium extorquens DM4 8191942 YP_003067374.1 CDS ptpS NC_012988.1 1683692 1684048 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; putative 6-pyruvol tetrahydrobiopterin synthase 1683692..1684048 Methylobacterium extorquens DM4 8191943 YP_003067375.1 CDS exsB NC_012988.1 1684051 1684782 D Evidence 2b : Function of strongly homologous gene; Product type pr : putative regulator; putative regulator, ATP-binding 1684051..1684782 Methylobacterium extorquens DM4 8195916 YP_003067376.1 CDS METDI1811 NC_012988.1 1684793 1685530 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative LmbE-like protein 1684793..1685530 Methylobacterium extorquens DM4 8195340 YP_003067377.1 CDS METDI1812 NC_012988.1 1685621 1686472 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15294902; Product type pe : putative enzyme; putative glycosyl transferase 1685621..1686472 Methylobacterium extorquens DM4 8191944 YP_003067378.1 CDS METDI1813 NC_012988.1 1686866 1687048 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1686866..1687048 Methylobacterium extorquens DM4 8191945 YP_003067379.1 CDS METDI1814 NC_012988.1 1687049 1687276 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1687049..1687276 Methylobacterium extorquens DM4 8191946 YP_003067380.1 CDS METDI1815 NC_012988.1 1687339 1687632 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1687339..1687632 Methylobacterium extorquens DM4 8191947 YP_003067381.1 CDS METDI1816 NC_012988.1 1687781 1688830 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase; putative UDP-N-acetylglucosamine, LPS N-acetylglucosamine transferase complement(1687781..1688830) Methylobacterium extorquens DM4 8191948 YP_003067382.1 CDS METDI1817 NC_012988.1 1688891 1689979 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12213785; Product type pe : putative enzyme; putative glycosyl transferase complement(1688891..1689979) Methylobacterium extorquens DM4 8191949 YP_003067383.1 CDS METDI1818 NC_012988.1 1689984 1691078 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11583114, 12788726, 15838019, 16934238; Product type pe : putative enzyme; putative glycosyl transferase complement(1689984..1691078) Methylobacterium extorquens DM4 8191950 YP_003067384.1 CDS METDI1819 NC_012988.1 1691187 1691366 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1691187..1691366) Methylobacterium extorquens DM4 8191951 YP_003067385.1 CDS METDI1820 NC_012988.1 1691307 1691513 D Evidence 6 : Doubtful CDS; hypothetical protein 1691307..1691513 Methylobacterium extorquens DM4 8191952 YP_003067386.1 CDS METDI1821 NC_012988.1 1691593 1691904 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Phosphoryl transfer system, HPr complement(1691593..1691904) Methylobacterium extorquens DM4 8191953 YP_003067387.1 CDS METDI1822 NC_012988.1 1692050 1692442 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative PTS system subfamily mannose/fructose-specific IIA component complement(1692050..1692442) Methylobacterium extorquens DM4 8191954 YP_003067388.1 CDS METDI1823 NC_012988.1 1692577 1693092 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative PTS system Hpr Kinase complement(1692577..1693092) Methylobacterium extorquens DM4 8191955 YP_003067389.1 CDS METDI1824 NC_012988.1 1693089 1694939 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11481430, 11743193, 11743194, 7559334, 8407839, 9422587, 9701808; Product type r : regulator; integral membrane sensor signal transduction histidine kinase complement(1693089..1694939) Methylobacterium extorquens DM4 8191956 YP_003067390.1 CDS chvI NC_012988.1 1694968 1695681 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7559334, 8407839; Product type r : regulator; Two-component response regulator ChvI complement(1694968..1695681) Methylobacterium extorquens DM4 8191957 YP_003067391.1 CDS METDI1826 NC_012988.1 1696081 1696896 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1696081..1696896 Methylobacterium extorquens DM4 8195167 YP_003067392.1 CDS lepA NC_012988.1 1697057 1698862 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1697057..1698862 Methylobacterium extorquens DM4 8191958 YP_003067393.1 CDS METDI1828 NC_012988.1 1699302 1700555 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative heavy metal efflux pump, HlyD family secretion protein 1699302..1700555 Methylobacterium extorquens DM4 8195627 YP_003067394.1 CDS czcA NC_012988.1 1700647 1703817 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Heavy metal efflux pump CzcA 1700647..1703817 Methylobacterium extorquens DM4 8191959 YP_003067395.1 CDS METDI1830 NC_012988.1 1704273 1705346 R Evidence 5 : No homology to any previously reported sequences; PubMedId : 1823284; hypothetical protein complement(1704273..1705346) Methylobacterium extorquens DM4 8195268 YP_003067396.1 CDS METDI1831 NC_012988.1 1705393 1708473 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12461003; Product type pe : putative enzyme; putative bifunctional N-terminal transglycosylase/C-terminal transpeptidase complement(1705393..1708473) Methylobacterium extorquens DM4 8191960 YP_003067397.1 CDS METDI1832 NC_012988.1 1708664 1709863 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1708664..1709863) Methylobacterium extorquens DM4 8191961 YP_003067398.1 CDS METDI1833 NC_012988.1 1710047 1711246 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1710047..1711246) Methylobacterium extorquens DM4 8191962 YP_003067399.1 CDS METDI1834 NC_012988.1 1711450 1711866 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative flagellar FlbT family protein 1711450..1711866 Methylobacterium extorquens DM4 8191963 YP_003067400.1 CDS METDI1835 NC_012988.1 1711963 1712178 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1711963..1712178) Methylobacterium extorquens DM4 8191964 YP_003067401.1 CDS METDI1836 NC_012988.1 1712273 1713436 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Acyltransferase 3 family complement(1712273..1713436) Methylobacterium extorquens DM4 8191965 YP_003067402.1 CDS METDI1837 NC_012988.1 1713740 1715125 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Metal-dependent phosphohydrolase, HD subdomain 1713740..1715125 Methylobacterium extorquens DM4 8191966 YP_003067403.1 CDS METDI1838 NC_012988.1 1715216 1715593 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1715216..1715593) Methylobacterium extorquens DM4 8191967 YP_003067404.1 CDS METDI1839 NC_012988.1 1715770 1716198 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1715770..1716198 Methylobacterium extorquens DM4 8191968 YP_003067405.1 CDS map NC_012988.1 1716321 1717073 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase complement(1716321..1717073) Methylobacterium extorquens DM4 8191969 YP_003067406.1 CDS METDI1841 NC_012988.1 1717682 1718341 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1717682..1718341 Methylobacterium extorquens DM4 8195660 YP_003067407.1 CDS METDI1842 NC_012988.1 1718376 1719182 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative CoxB complement(1718376..1719182) Methylobacterium extorquens DM4 8191970 YP_003067408.1 CDS METDI1843 NC_012988.1 1719668 1720525 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1719668..1720525) Methylobacterium extorquens DM4 8191971 YP_003067409.1 CDS METDI1844 NC_012988.1 1720525 1721880 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2134335, 2793824; Product type r : regulator; two-component DctB-like sigma-54 specific transcriptional regulator, Fis subfamily; with N-terminal response regulator receiver and ATPase domains complement(1720525..1721880) Methylobacterium extorquens DM4 8191972 YP_003067410.1 CDS METDI1845 NC_012988.1 1721870 1723750 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative sensor histidine kinase precursor, putative transcriptional regulator of C4 dicarboxylate transporter complement(1721870..1723750) Methylobacterium extorquens DM4 8191973 YP_003067411.1 CDS tauB NC_012988.1 1724014 1724895 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9401024, 96404792; Product type t : transporter; taurine transport protein (ABC superfamily, atp_bind) complement(1724014..1724895) Methylobacterium extorquens DM4 8191974 YP_003067412.1 CDS ssuC NC_012988.1 1724904 1725689 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; alkanesulfonate transporter subunit ; membrane component of ABC superfamily complement(1724904..1725689) Methylobacterium extorquens DM4 8196182 YP_003067413.1 CDS METDI1848 NC_012988.1 1725738 1726718 R Evidence 2b : Function of strongly homologous gene; Product type pf : putative factor; Extracellular solute-binding protein, family 3 precursor complement(1725738..1726718) Methylobacterium extorquens DM4 8196159 YP_003067414.1 CDS minC NC_012988.1 1726982 1727710 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1726982..1727710) Methylobacterium extorquens DM4 8191975 YP_003067415.1 CDS METDI1850 NC_012988.1 1727837 1729105 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1727837..1729105) Methylobacterium extorquens DM4 8195696 YP_003067416.1 CDS typA NC_012988.1 1729444 1731270 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7783627, 9298646, 9622352, 9642082; Product type f : factor; GTP-binding elongation factor family protein with P-loop containing NTP hydrolase domain 1729444..1731270 Methylobacterium extorquens DM4 8191976 YP_003067417.1 CDS METDI1852 NC_012988.1 1731413 1733101 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative methyl-accepting chemotaxis sensory transducer complement(1731413..1733101) Methylobacterium extorquens DM4 8196291 YP_003067418.1 CDS minC NC_012988.1 1733473 1734159 D blocks the formation of polar Z-ring septums; septum formation inhibitor 1733473..1734159 Methylobacterium extorquens DM4 8191977 YP_003067419.1 CDS minD NC_012988.1 1734172 1734987 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10096083, 11248256, 12519187, 90138951, 1836760, 1729224, 99248411; Product type e : enzyme; membrane ATPase of the MinC-MinD-MinE system 1734172..1734987 Methylobacterium extorquens DM4 8195697 YP_003067420.1 CDS minE NC_012988.1 1734984 1735271 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12271122; Product type f : factor; cell division topological specificity factor 1734984..1735271 Methylobacterium extorquens DM4 8195698 YP_003067421.1 CDS METDI1856 NC_012988.1 1735547 1736926 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cytochrome P450 family enzyme complement(1735547..1736926) Methylobacterium extorquens DM4 8195699 YP_003067422.1 CDS METDI1857 NC_012988.1 1737181 1738074 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1737181..1738074 Methylobacterium extorquens DM4 8191978 YP_003067423.1 CDS METDI1858 NC_012988.1 1738232 1740082 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycoside hydrolase 1738232..1740082 Methylobacterium extorquens DM4 8191979 YP_003067424.1 CDS METDI1859 NC_012988.1 1740091 1741053 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dehydrogenase protein 1740091..1741053 Methylobacterium extorquens DM4 8191980 YP_003067425.1 CDS METDI1862 NC_012988.1 1742106 1743521 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative carbohydrate-selective porin 1742106..1743521 Methylobacterium extorquens DM4 8191983 YP_003067426.1 CDS METDI1865 NC_012988.1 1744620 1746242 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative dipeptide transporter; periplasmic binding component of ABC superfamily (dppA-like) 1744620..1746242 Methylobacterium extorquens DM4 8191986 YP_003067427.1 CDS METDI1866 NC_012988.1 1746401 1747354 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative dipeptide transporter; membrane component of ABC superfamily (dppB-like) 1746401..1747354 Methylobacterium extorquens DM4 8191987 YP_003067428.1 CDS METDI1867 NC_012988.1 1747371 1748306 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative dipeptide transporter; membrane component of ABC superfamily (dppC-like) 1747371..1748306 Methylobacterium extorquens DM4 8191988 YP_003067429.1 CDS dppF NC_012988.1 1748303 1749358 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7536291; Product type t : transporter; dipeptide transporter; ATP-binding component of ABC superfamily 1748303..1749358 Methylobacterium extorquens DM4 8191989 YP_003067430.1 CDS dppD NC_012988.1 1749355 1750389 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2821267, 3926486, 7536291; Product type t : transporter; dipeptide transporter; ATP-binding component of ABC superfamily 1749355..1750389 Methylobacterium extorquens DM4 8195315 YP_003067431.1 CDS METDI1870 NC_012988.1 1750750 1752249 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10984043, 1339433; Product type e : enzyme; aldehyde dehydrogenase, putative malonate/methylmalonate semialdehyde dehydrogenase MmsA complement(1750750..1752249) Methylobacterium extorquens DM4 8195314 YP_003067432.1 CDS METDI1871 NC_012988.1 1752315 1752791 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative carbon monoxide dehydrogenase accessory protein CoxG complement(1752315..1752791) Methylobacterium extorquens DM4 8191990 YP_003067433.1 CDS METDI1872 NC_012988.1 1752821 1753525 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ATP transport, ATPase complement(1752821..1753525) Methylobacterium extorquens DM4 8191991 YP_003067434.1 CDS METDI1873 NC_012988.1 1753518 1754288 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, ATPase complement(1753518..1754288) Methylobacterium extorquens DM4 8191992 YP_003067435.1 CDS METDI1874 NC_012988.1 1754285 1755298 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, permease complement(1754285..1755298) Methylobacterium extorquens DM4 8191993 YP_003067436.1 CDS METDI1875 NC_012988.1 1755310 1756200 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, permease complement(1755310..1756200) Methylobacterium extorquens DM4 8191994 YP_003067437.1 CDS METDI1876 NC_012988.1 1756218 1757495 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter, periplasmic protein (tat pathway signal) complement(1756218..1757495) Methylobacterium extorquens DM4 8191995 YP_003067438.1 CDS METDI1877 NC_012988.1 1757532 1759910 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, molybdopterin-binding subunit; putative carbon monoxide dehydrogenase, large subunit CoxL complement(1757532..1759910) Methylobacterium extorquens DM4 8191996 YP_003067439.1 CDS METDI1878 NC_012988.1 1759907 1760410 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10430865, 12475995; Product type e : enzyme; oxidoreductase, 2Fe-2S subunit; putative carbon monoxide dehydrogenase, small subunit CoxS complement(1759907..1760410) Methylobacterium extorquens DM4 8191997 YP_003067440.1 CDS METDI1879 NC_012988.1 1760407 1761309 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, FAD-binding subunit; putative carbon monoxide dehydrogenase, medium subunit CoxM complement(1760407..1761309) Methylobacterium extorquens DM4 8191998 YP_003067441.1 CDS METDI1880 NC_012988.1 1761414 1762109 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10400605; Product type r : regulator; transcriptional regulatory protein (TetR family) 1761414..1762109 Methylobacterium extorquens DM4 8191999 YP_003067442.1 CDS METDI1881 NC_012988.1 1762851 1764143 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11976087; Product type e : enzyme; N-carbamyl-L-amino acid hydrolase (amidase, hydantoinase/carbamoylase family) 1762851..1764143 Methylobacterium extorquens DM4 8192000 YP_003067443.1 CDS aptA NC_012988.1 1764494 1765831 D catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; beta alanine--pyruvate transaminase 1764494..1765831 Methylobacterium extorquens DM4 8192001 YP_003067444.1 CDS METDI1883 NC_012988.1 1766159 1766575 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD-dependent aldehyde dehydrogenase 1766159..1766575 Methylobacterium extorquens DM4 8195078 YP_003067445.1 CDS METDI1884 NC_012988.1 1766431 1766766 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1766431..1766766) Methylobacterium extorquens DM4 8192002 YP_003067446.1 CDS METDI1885 NC_012988.1 1766854 1767099 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1766854..1767099 Methylobacterium extorquens DM4 8192003 YP_003067447.1 CDS METDI1886 NC_012988.1 1767216 1767524 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1767216..1767524) Methylobacterium extorquens DM4 8192004 YP_003067448.1 CDS METDI1887 NC_012988.1 1767798 1771133 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; DEAD/DEAH box helicase domain protein complement(1767798..1771133) Methylobacterium extorquens DM4 8192005 YP_003067449.1 CDS METDI1888 NC_012988.1 1771136 1771360 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1771136..1771360) Methylobacterium extorquens DM4 8192006 YP_003067450.1 CDS amtB NC_012988.1 1771412 1772650 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ammonium transport protein (Amt family) complement(1771412..1772650) Methylobacterium extorquens DM4 8192007 YP_003067451.1 CDS METDI1890 NC_012988.1 1772744 1773757 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative urea transporter complement(1772744..1773757) Methylobacterium extorquens DM4 8195074 YP_003067452.1 CDS ureD NC_012988.1 1773773 1774708 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type cp : cell process; Urease accessory protein ureD complement(1773773..1774708) Methylobacterium extorquens DM4 8192008 YP_003067453.1 CDS ureG NC_012988.1 1774713 1775360 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type cp : cell process; urease accessory protein UreG complement(1774713..1775360) Methylobacterium extorquens DM4 8196317 YP_003067454.1 CDS ureF NC_012988.1 1775381 1776061 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; Urease accessory protein ureF complement(1775381..1776061) Methylobacterium extorquens DM4 8196326 YP_003067455.1 CDS ureE NC_012988.1 1776103 1776756 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; Urease accessory protein ureE complement(1776103..1776756) Methylobacterium extorquens DM4 8196322 YP_003067456.1 CDS ccrB NC_012988.1 1776780 1777163 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1776780..1777163) Methylobacterium extorquens DM4 8196319 YP_003067457.1 CDS METDI1897 NC_012988.1 1777173 1777538 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12904550, 8844142; Product type m : membrane component; putative integral membrane protein; putative CrcB protein complement(1777173..1777538) Methylobacterium extorquens DM4 8192009 YP_003067458.1 CDS ureC NC_012988.1 1777618 1779336 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(1777618..1779336) Methylobacterium extorquens DM4 8192010 YP_003067459.1 CDS ureB NC_012988.1 1779373 1779783 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; urease beta subunit complement(1779373..1779783) Methylobacterium extorquens DM4 8196314 YP_003067460.1 CDS ureA NC_012988.1 1779808 1780110 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; urease gamma subunit complement(1779808..1780110) Methylobacterium extorquens DM4 8196312 YP_003067461.1 CDS METDI1901 NC_012988.1 1780750 1782864 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical exported protein, putative outer membrane receptor protein 1780750..1782864 Methylobacterium extorquens DM4 8196308 YP_003067462.1 CDS METDI1902 NC_012988.1 1782861 1783592 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1782861..1783592 Methylobacterium extorquens DM4 8192011 YP_003067463.1 CDS METDI1903 NC_012988.1 1783648 1783863 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1783648..1783863) Methylobacterium extorquens DM4 8192012 YP_003067464.1 CDS METDI1904 NC_012988.1 1783995 1784606 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1783995..1784606 Methylobacterium extorquens DM4 8192013 YP_003067465.1 CDS METDI1905 NC_012988.1 1784676 1785077 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1784676..1785077) Methylobacterium extorquens DM4 8192014 YP_003067466.1 CDS METDI1906 NC_012988.1 1785161 1785502 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1785161..1785502 Methylobacterium extorquens DM4 8192015 YP_003067467.1 CDS METDI1907 NC_012988.1 1788192 1788581 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1788192..1788581 Methylobacterium extorquens DM4 8192016 YP_003067468.1 CDS METDI1908 NC_012988.1 1788745 1789308 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase 1788745..1789308 Methylobacterium extorquens DM4 8192017 YP_003067469.1 CDS METDI1909 NC_012988.1 1789322 1789636 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1789322..1789636) Methylobacterium extorquens DM4 8192018 YP_003067470.1 CDS METDI1910 NC_012988.1 1789756 1790313 D Evidence 6 : Doubtful CDS; hypothetical protein 1789756..1790313 Methylobacterium extorquens DM4 8192019 YP_003067471.1 CDS METDI1911 NC_012988.1 1790443 1790928 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1790443..1790928) Methylobacterium extorquens DM4 8192020 YP_003067472.1 CDS METDI1912 NC_012988.1 1791081 1791554 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1791081..1791554) Methylobacterium extorquens DM4 8192021 YP_003067473.1 CDS METDI1913 NC_012988.1 1792042 1793616 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ADP-ribosyl glycohydrolase family protein 1792042..1793616 Methylobacterium extorquens DM4 8192022 YP_003067474.1 CDS METDI1914 NC_012988.1 1793613 1793981 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1793613..1793981 Methylobacterium extorquens DM4 8192023 YP_003067475.1 CDS METDI1915 NC_012988.1 1794199 1796430 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative P4 family phage/plasmid primase complement(1794199..1796430) Methylobacterium extorquens DM4 8192024 YP_003067476.1 CDS METDI1916 NC_012988.1 1798479 1798907 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1798479..1798907 Methylobacterium extorquens DM4 8196258 YP_003067477.1 CDS METDI1917 NC_012988.1 1799177 1799731 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) complement(1799177..1799731) Methylobacterium extorquens DM4 8192026 YP_003067478.1 CDS METDI1918 NC_012988.1 1799506 1799931 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) complement(1799506..1799931) Methylobacterium extorquens DM4 8192027 YP_003067479.1 CDS METDI1919 NC_012988.1 1799957 1800616 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1799957..1800616) Methylobacterium extorquens DM4 8192028 YP_003067480.1 CDS METDI1920 NC_012988.1 1800604 1800948 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1800604..1800948) Methylobacterium extorquens DM4 8192029 YP_003067481.1 CDS METDI1921 NC_012988.1 1800884 1801237 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphoglycerate/bisphosphoglycerate mutase complement(1800884..1801237) Methylobacterium extorquens DM4 8192030 YP_003067482.1 CDS METDI1922 NC_012988.1 1801460 1801936 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1801460..1801936) Methylobacterium extorquens DM4 8192031 YP_003067483.1 CDS METDI1923 NC_012988.1 1802427 1803104 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Metal-dependent phosphohydrolase, HD subdomain complement(1802427..1803104) Methylobacterium extorquens DM4 8192032 YP_003067484.1 CDS METDI1924 NC_012988.1 1803166 1804188 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, AraC family 1803166..1804188 Methylobacterium extorquens DM4 8192033 YP_003067485.1 CDS METDI1925 NC_012988.1 1804264 1805106 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1804264..1805106) Methylobacterium extorquens DM4 8192034 YP_003067486.1 CDS METDI1926 NC_012988.1 1805224 1805367 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1805224..1805367) Methylobacterium extorquens DM4 8192035 YP_003067487.1 CDS METDI1927 NC_012988.1 1805759 1806148 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1805759..1806148) Methylobacterium extorquens DM4 8192036 YP_003067488.1 CDS METDI1928 NC_012988.1 1806540 1806806 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1806540..1806806) Methylobacterium extorquens DM4 8192037 YP_003067489.1 CDS METDI1929 NC_012988.1 1807240 1808661 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase precursor complement(1807240..1808661) Methylobacterium extorquens DM4 8192038 YP_003067490.1 CDS METDI1930 NC_012988.1 1808831 1809880 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium/hydrogen exchanger complement(1808831..1809880) Methylobacterium extorquens DM4 8192039 YP_003067491.1 CDS METDI1932 NC_012988.1 1810622 1811047 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) 1810622..1811047 Methylobacterium extorquens DM4 8192041 YP_003067492.1 CDS METDI1933 NC_012988.1 1810822 1811376 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) 1810822..1811376 Methylobacterium extorquens DM4 8192042 YP_003067493.1 CDS METDI1934 NC_012988.1 1811637 1811879 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1811637..1811879 Methylobacterium extorquens DM4 8192043 YP_003067494.1 CDS METDI1935 NC_012988.1 1811987 1813171 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1811987..1813171) Methylobacterium extorquens DM4 8192044 YP_003067495.1 CDS METDI1936 NC_012988.1 1813457 1814209 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 2) complement(1813457..1814209) Methylobacterium extorquens DM4 8192045 YP_003067496.1 CDS METDI1937 NC_012988.1 1814317 1814598 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi3, IS3 family (ORF 1) complement(1814317..1814598) Methylobacterium extorquens DM4 8192046 YP_003067497.1 CDS METDI1938 NC_012988.1 1814850 1815155 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1814850..1815155) Methylobacterium extorquens DM4 8192047 YP_003067498.1 CDS METDI1939 NC_012988.1 1815166 1815849 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1815166..1815849) Methylobacterium extorquens DM4 8192048 YP_003067499.1 CDS METDI1940 NC_012988.1 1815861 1816988 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(1815861..1816988) Methylobacterium extorquens DM4 8192049 YP_003067500.1 CDS METDI1941 NC_012988.1 1817098 1819530 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10664842; Product type pe : putative enzyme; putative N,N-dimethylformamidase large subunit complement(1817098..1819530) Methylobacterium extorquens DM4 8192050 YP_003067501.1 CDS METDI1942 NC_012988.1 1819653 1820093 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative N,N-dimethylformamidase, small subunit complement(1819653..1820093) Methylobacterium extorquens DM4 8192051 YP_003067502.1 CDS METDI1943 NC_012988.1 1820463 1821161 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative leucine/isoleucine/valine transporter subunit (ATP-binding component of ABC superfamily) (livF) complement(1820463..1821161) Methylobacterium extorquens DM4 8192052 YP_003067503.1 CDS METDI1944 NC_012988.1 1821164 1821904 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative leucine/isoleucine/valine transporter subunit (ATP-binding component of ABC superfamily) (livG) complement(1821164..1821904) Methylobacterium extorquens DM4 8192053 YP_003067504.1 CDS METDI1945 NC_012988.1 1821920 1823041 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Branched-chain amino acid ABC transporter, permease protein complement(1821920..1823041) Methylobacterium extorquens DM4 8192054 YP_003067505.1 CDS METDI1946 NC_012988.1 1823091 1823975 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, membrane spanning protein complement(1823091..1823975) Methylobacterium extorquens DM4 8192055 YP_003067506.1 CDS METDI1947 NC_012988.1 1824043 1825329 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10508151, 10708652, 1762155, 1907262, 7813419; Product type pr : putative regulator; putative aliphatic amidase expression-regulating protein precursor, amiC complement(1824043..1825329) Methylobacterium extorquens DM4 8192056 YP_003067507.1 CDS METDI1948 NC_012988.1 1826028 1826195 D Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein 1826028..1826195 Methylobacterium extorquens DM4 8192057 YP_003067508.1 CDS METDI1949 NC_012988.1 1826123 1826338 D Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein 1826123..1826338 Methylobacterium extorquens DM4 8192058 YP_003067509.1 CDS METDI1950 NC_012988.1 1826981 1827253 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1826981..1827253 Methylobacterium extorquens DM4 8192059 YP_003067510.1 CDS METDI1951 NC_012988.1 1827465 1827641 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1827465..1827641) Methylobacterium extorquens DM4 8192060 YP_003067511.1 CDS METDI1952 NC_012988.1 1827765 1827962 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1827765..1827962) Methylobacterium extorquens DM4 8192061 YP_003067512.1 CDS yliI NC_012988.1 1827989 1829113 D Evidence 2b : Function of strongly homologous gene; PubMedId : 16522795, 16864586; Product type e : enzyme; PQQ-dependent aldose sugar dehydrogenase precursor (asd) 1827989..1829113 Methylobacterium extorquens DM4 8192062 YP_003067513.1 CDS METDI1954 NC_012988.1 1829147 1830148 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative alpha/beta hydrolase complement(1829147..1830148) Methylobacterium extorquens DM4 8196373 YP_003067514.1 CDS METDI1955 NC_012988.1 1830276 1830488 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1830276..1830488) Methylobacterium extorquens DM4 8192063 YP_003067515.1 CDS METDI1956 NC_012988.1 1830475 1830642 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1830475..1830642) Methylobacterium extorquens DM4 8192064 YP_003067516.1 CDS METDI1957 NC_012988.1 1831162 1831827 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1831162..1831827 Methylobacterium extorquens DM4 8192065 YP_003067517.1 CDS METDI1958 NC_012988.1 1831844 1833349 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1831844..1833349 Methylobacterium extorquens DM4 8192066 YP_003067518.1 CDS METDI1959 NC_012988.1 1833415 1834386 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1833415..1834386 Methylobacterium extorquens DM4 8192067 YP_003067519.1 CDS METDI1960 NC_012988.1 1834697 1835512 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 1834697..1835512 Methylobacterium extorquens DM4 8192068 YP_003067520.1 CDS METDI1961 NC_012988.1 1835827 1835970 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1835827..1835970) Methylobacterium extorquens DM4 8192069 YP_003067521.1 CDS gpmA NC_012988.1 1836638 1837276 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8110200; Product type e : enzyme; phosphoglyceromutase complement(1836638..1837276) Methylobacterium extorquens DM4 8192070 YP_003067522.1 CDS METDI1963 NC_012988.1 1837275 1837463 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1837275..1837463 Methylobacterium extorquens DM4 8195528 YP_003067523.1 CDS METDI1964 NC_012988.1 1837548 1838015 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1837548..1838015 Methylobacterium extorquens DM4 8192071 YP_003067524.1 CDS METDI1965 NC_012988.1 1838239 1838484 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1838239..1838484) Methylobacterium extorquens DM4 8192072 YP_003067525.1 CDS METDI1966 NC_012988.1 1838677 1838895 D Evidence 6 : Doubtful CDS; hypothetical protein 1838677..1838895 Methylobacterium extorquens DM4 8192073 YP_003067526.1 CDS METDI1967 NC_012988.1 1838911 1839090 D Evidence 6 : Doubtful CDS; hypothetical protein 1838911..1839090 Methylobacterium extorquens DM4 8192074 YP_003067527.1 CDS METDI1968 NC_012988.1 1839087 1839212 D Evidence 6 : Doubtful CDS; hypothetical protein 1839087..1839212 Methylobacterium extorquens DM4 8192075 YP_003067528.1 CDS METDI1969 NC_012988.1 1839553 1839984 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1839553..1839984 Methylobacterium extorquens DM4 8192076 YP_003067529.1 CDS METDI1970 NC_012988.1 1840097 1840861 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 1840097..1840861 Methylobacterium extorquens DM4 8192077 YP_003067530.1 CDS METDI1971 NC_012988.1 1840941 1841477 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1840941..1841477) Methylobacterium extorquens DM4 8192078 YP_003067531.1 CDS METDI1972 NC_012988.1 1840947 1841126 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1840947..1841126 Methylobacterium extorquens DM4 8192079 YP_003067532.1 CDS METDI1973 NC_012988.1 1841513 1842403 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Acetyl-hydrolase complement(1841513..1842403) Methylobacterium extorquens DM4 8192080 YP_003067533.1 CDS METDI1974 NC_012988.1 1843203 1844708 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9045826; Product type pr : putative regulator; putative hybrid histidine kinase with PAS sensor and response receiver regulator domains complement(1843203..1844708) Methylobacterium extorquens DM4 8192081 YP_003067534.1 CDS METDI1975 NC_012988.1 1844710 1846695 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor histidine kinase with multiple PAS and GAF domains complement(1844710..1846695) Methylobacterium extorquens DM4 8192082 YP_003067535.1 CDS METDI1976 NC_012988.1 1847185 1848636 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative cytochrome P450 1847185..1848636 Methylobacterium extorquens DM4 8192083 YP_003067536.1 CDS METDI1977 NC_012988.1 1848614 1851061 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sensory box-containing diguanylate cyclase/phosphodiesterase; permease, PAS/PAC, GGDEF and EAL domains 1848614..1851061 Methylobacterium extorquens DM4 8192084 YP_003067537.1 CDS METDI1978 NC_012988.1 1851233 1852072 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative tRNA delta(2)-isopentenylpyrophosphate transferase (IPP transferase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPTase) (IPPT) complement(1851233..1852072) Methylobacterium extorquens DM4 8192085 YP_003067538.1 CDS METDI1979 NC_012988.1 1852085 1853065 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10960107, 9274035; Product type pe : putative enzyme; putative nosX precursor (nitrous oxide reductase) complement(1852085..1853065) Methylobacterium extorquens DM4 8192086 YP_003067539.1 CDS METDI1980 NC_012988.1 1853071 1855188 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12186758; Product type pr : putative regulator; putative regulatory protein NosR complement(1853071..1855188) Methylobacterium extorquens DM4 8192087 YP_003067540.1 CDS METDI1981 NC_012988.1 1855185 1856201 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1855185..1856201) Methylobacterium extorquens DM4 8192088 YP_003067541.1 CDS METDI1982 NC_012988.1 1856249 1857475 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1856249..1857475) Methylobacterium extorquens DM4 8192089 YP_003067542.1 CDS METDI1983 NC_012988.1 1857637 1858059 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10075429; Product type c : carrier; cytochrome c550 1857637..1858059 Methylobacterium extorquens DM4 8192090 YP_003067543.1 CDS METDI1984 NC_012988.1 1858074 1858940 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1858074..1858940 Methylobacterium extorquens DM4 8192091 YP_003067544.1 CDS exa NC_012988.1 1859231 1860994 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10736230; Product type e : enzyme; Quinoprotein ethanol dehydrogenase precursor (QEDH) 1859231..1860994 Methylobacterium extorquens DM4 8192092 YP_003067545.1 CDS METDI1986 NC_012988.1 1861316 1862908 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator superfamily complement(1861316..1862908) Methylobacterium extorquens DM4 8195338 YP_003067546.1 CDS METDI1987 NC_012988.1 1862811 1863212 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1862811..1863212 Methylobacterium extorquens DM4 8192093 YP_003067547.1 CDS METDI1988 NC_012988.1 1863272 1863514 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1863272..1863514 Methylobacterium extorquens DM4 8192094 YP_003067548.1 CDS METDI1989 NC_012988.1 1863492 1863737 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1863492..1863737) Methylobacterium extorquens DM4 8192095 YP_003067549.1 CDS METDI1990 NC_012988.1 1863734 1864426 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1863734..1864426) Methylobacterium extorquens DM4 8192096 YP_003067550.1 CDS METDI1991 NC_012988.1 1864423 1864581 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1864423..1864581) Methylobacterium extorquens DM4 8192097 YP_003067551.1 CDS METDI1992 NC_012988.1 1864776 1864904 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1864776..1864904) Methylobacterium extorquens DM4 8192098 YP_003067552.1 CDS METDI1993 NC_012988.1 1864948 1865445 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1864948..1865445) Methylobacterium extorquens DM4 8192099 YP_003067553.1 CDS METDI1994 NC_012988.1 1865511 1866272 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1865511..1866272) Methylobacterium extorquens DM4 8192100 YP_003067554.1 CDS METDI1995 NC_012988.1 1866335 1866661 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1866335..1866661 Methylobacterium extorquens DM4 8192101 YP_003067555.1 CDS METDI1996 NC_012988.1 1866680 1867189 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1866680..1867189) Methylobacterium extorquens DM4 8192102 YP_003067556.1 CDS METDI1997 NC_012988.1 1867186 1869303 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase complement(1867186..1869303) Methylobacterium extorquens DM4 8192103 YP_003067557.1 CDS METDI1998 NC_012988.1 1869855 1870121 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1869855..1870121 Methylobacterium extorquens DM4 8192104 YP_003067558.1 CDS METDI1999 NC_012988.1 1870136 1870285 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1870136..1870285 Methylobacterium extorquens DM4 8192105 YP_003067559.1 CDS METDI2000 NC_012988.1 1870344 1870691 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1870344..1870691) Methylobacterium extorquens DM4 8192106 YP_003067560.1 CDS METDI2001 NC_012988.1 1870775 1871521 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(1870775..1871521) Methylobacterium extorquens DM4 8192107 YP_003067561.1 CDS METDI2002 NC_012988.1 1871641 1872555 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(1871641..1872555) Methylobacterium extorquens DM4 8192108 YP_003067562.1 CDS METDI2003 NC_012988.1 1872729 1873565 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1872729..1873565) Methylobacterium extorquens DM4 8192109 YP_003067563.1 CDS METDI2004 NC_012988.1 1873733 1874545 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1873733..1874545 Methylobacterium extorquens DM4 8192110 YP_003067564.1 CDS METDI2005 NC_012988.1 1874545 1874871 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10866828; Product type pe : putative enzyme; putative cytochrome c, class I 1874545..1874871 Methylobacterium extorquens DM4 8192111 YP_003067565.1 CDS METDI2006 NC_012988.1 1874947 1875699 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1319772, 1551834, 1766374, 7559356; Product type r : regulator; transcriptional regulator, Crp/Fnr family complement(1874947..1875699) Methylobacterium extorquens DM4 8192112 YP_003067566.1 CDS METDI2007 NC_012988.1 1876064 1877719 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter related, fused ATPase and permease domains (CydD-like) complement(1876064..1877719) Methylobacterium extorquens DM4 8192113 YP_003067567.1 CDS METDI2009 NC_012988.1 1877674 1879317 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter related, fused ATPase and permease domains (CydD-like) complement(1877674..1879317) Methylobacterium extorquens DM4 8192114 YP_003067568.1 CDS cydA NC_012988.1 1879417 1881006 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; cytochrome d terminal oxidase, polypeptide subunit I 1879417..1881006 Methylobacterium extorquens DM4 8192115 YP_003067569.1 CDS cydB NC_012988.1 1881072 1882226 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; cytochrome d terminal oxidase, polypeptide subunit II 1881072..1882226 Methylobacterium extorquens DM4 8195239 YP_003067570.1 CDS METDI2012 NC_012988.1 1882280 1882411 D Evidence 4 : Homologs of previously reported genes of unknown function; putative exported protein, putative cyd operon protein 1882280..1882411 Methylobacterium extorquens DM4 8195240 YP_003067571.1 CDS METDI2013 NC_012988.1 1882644 1883396 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2653814; Product type pr : putative regulator; transcriptional regulator, DeoR family complement(1882644..1883396) Methylobacterium extorquens DM4 8192116 YP_003067572.1 CDS METDI2014 NC_012988.1 1883562 1885136 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A) complement(1883562..1885136) Methylobacterium extorquens DM4 8192117 YP_003067573.1 CDS METDI2015 NC_012988.1 1885663 1888089 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10199407; hypothetical protein 1885663..1888089 Methylobacterium extorquens DM4 8192118 YP_003067574.1 CDS METDI2016 NC_012988.1 1888294 1889034 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1888294..1889034 Methylobacterium extorquens DM4 8192119 YP_003067575.1 CDS celA NC_012988.1 1889363 1891867 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7860585; Product type e : enzyme; Cellulose synthase (UDP-forming) 1889363..1891867 Methylobacterium extorquens DM4 8192120 YP_003067576.1 CDS METDI2018 NC_012988.1 1891864 1894506 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10376842; Product type pe : putative enzyme; putative CelB-like protein 1891864..1894506 Methylobacterium extorquens DM4 8195161 YP_003067577.1 CDS METDI2019 NC_012988.1 1894506 1895789 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10376842; Product type pe : putative enzyme; putative cellulase, endoglucanase (celC) 1894506..1895789 Methylobacterium extorquens DM4 8192121 YP_003067578.1 CDS METDI2020 NC_012988.1 1895774 1897837 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1895774..1897837 Methylobacterium extorquens DM4 8192122 YP_003067579.1 CDS METDI2021 NC_012988.1 1897834 1898847 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1897834..1898847 Methylobacterium extorquens DM4 8192123 YP_003067580.1 CDS METDI2028 NC_012988.1 1906274 1910164 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase complement(1906274..1910164) Methylobacterium extorquens DM4 8196259 YP_003067581.1 CDS METDI2029 NC_012988.1 1910188 1910556 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1910188..1910556) Methylobacterium extorquens DM4 8192125 YP_003067582.1 CDS METDI2030 NC_012988.1 1910821 1911714 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1910821..1911714 Methylobacterium extorquens DM4 8192126 YP_003067583.1 CDS METDI2031 NC_012988.1 1912091 1912861 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1912091..1912861) Methylobacterium extorquens DM4 8192127 YP_003067584.1 CDS METDI2032 NC_012988.1 1912947 1913510 R Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; possibly involved in prevention of copper toxicity; RNA polymerase sigma factor complement(1912947..1913510) Methylobacterium extorquens DM4 8192128 YP_003067585.1 CDS METDI2033 NC_012988.1 1913747 1915051 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Peptidoglycan-binding protein complement(1913747..1915051) Methylobacterium extorquens DM4 8192129 YP_003067586.1 CDS METDI2034 NC_012988.1 1915336 1915749 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1915336..1915749 Methylobacterium extorquens DM4 8192130 YP_003067587.1 CDS METDI2035 NC_012988.1 1915799 1916866 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1915799..1916866 Methylobacterium extorquens DM4 8192131 YP_003067588.1 CDS METDI2036 NC_012988.1 1916982 1917506 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1916982..1917506 Methylobacterium extorquens DM4 8192132 YP_003067589.1 CDS METDI2037 NC_012988.1 1917496 1918143 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1917496..1918143 Methylobacterium extorquens DM4 8192133 YP_003067590.1 CDS METDI2038 NC_012988.1 1918287 1918643 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1918287..1918643 Methylobacterium extorquens DM4 8192134 YP_003067591.1 CDS METDI2039 NC_012988.1 1918686 1920833 D Evidence 2b : Function of strongly homologous gene; Product type prc : putative receptor; putative outer membrane receptor for iron transport 1918686..1920833 Methylobacterium extorquens DM4 8192135 YP_003067592.1 CDS METDI2040 NC_012988.1 1921079 1922926 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1921079..1922926 Methylobacterium extorquens DM4 8192136 YP_003067593.1 CDS METDI2041 NC_012988.1 1923077 1924549 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1923077..1924549) Methylobacterium extorquens DM4 8192137 YP_003067594.1 CDS METDI2042 NC_012988.1 1924654 1925313 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11106435, 9826185; Product type r : regulator; transcriptional regulator, GntR family complement(1924654..1925313) Methylobacterium extorquens DM4 8192138 YP_003067595.1 CDS METDI2043 NC_012988.1 1925489 1926511 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; putative tripartite ATP-independent periplasmic transporter, periplasmic binding protein precursor (tat pathway signal) 1925489..1926511 Methylobacterium extorquens DM4 8192139 YP_003067596.1 CDS METDI2044 NC_012988.1 1926508 1927233 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative tripartite ATP-independent periplasmic transporter, permease (DctQ) subunit; putative membrane protein 1926508..1927233 Methylobacterium extorquens DM4 8192140 YP_003067597.1 CDS METDI2045 NC_012988.1 1927230 1928582 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative tripartite ATP-independent periplasmic transporter, putative membrane component 1927230..1928582 Methylobacterium extorquens DM4 8192141 YP_003067598.1 CDS METDI2046 NC_012988.1 1928750 1928947 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1928750..1928947 Methylobacterium extorquens DM4 8192142 YP_003067600.1 CDS METDI2048 NC_012988.1 1929727 1929960 D Evidence 6 : Doubtful CDS; hypothetical protein 1929727..1929960 Methylobacterium extorquens DM4 8192144 YP_003067601.1 CDS cysK NC_012988.1 1930028 1931074 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9108143, 9406390; Product type e : enzyme; Cysteine synthase 1930028..1931074 Methylobacterium extorquens DM4 8192145 YP_003067602.1 CDS METDI2050 NC_012988.1 1931187 1931342 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1931187..1931342 Methylobacterium extorquens DM4 8195258 YP_003067603.1 CDS METDI2051 NC_012988.1 1931441 1932916 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1931441..1932916) Methylobacterium extorquens DM4 8192146 YP_003067604.1 CDS METDI2052 NC_012988.1 1933096 1933542 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1933096..1933542 Methylobacterium extorquens DM4 8192147 YP_003067605.1 CDS METDI2053 NC_012988.1 1933812 1939118 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1933812..1939118 Methylobacterium extorquens DM4 8192148 YP_003067606.1 CDS pbpC NC_012988.1 1939123 1941324 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8335642; Product type e : enzyme; penicillin binding protein 1939123..1941324 Methylobacterium extorquens DM4 8192149 YP_003067607.1 CDS sugE NC_012988.1 1941463 1941783 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; multidrug efflux system protein 1941463..1941783 Methylobacterium extorquens DM4 8195830 YP_003067608.1 CDS METDI2056 NC_012988.1 1941788 1942588 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1941788..1942588) Methylobacterium extorquens DM4 8196174 YP_003067609.1 CDS METDI2057 NC_012988.1 1942640 1943275 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sortase (surface protein transpeptidase) precursor complement(1942640..1943275) Methylobacterium extorquens DM4 8192150 YP_003067610.1 CDS METDI2058 NC_012988.1 1943272 1945473 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1943272..1945473) Methylobacterium extorquens DM4 8192151 YP_003067611.1 CDS METDI2059 NC_012988.1 1945718 1946329 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphoglycerate mutase domain protein 1945718..1946329 Methylobacterium extorquens DM4 8192152 YP_003067612.1 CDS METDI2060 NC_012988.1 1946417 1947157 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1946417..1947157) Methylobacterium extorquens DM4 8192153 YP_003067613.1 CDS METDI2061 NC_012988.1 1947268 1948278 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1947268..1948278) Methylobacterium extorquens DM4 8192154 YP_003067614.1 CDS METDI2062 NC_012988.1 1948269 1948946 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1948269..1948946) Methylobacterium extorquens DM4 8192155 YP_003067615.1 CDS cycL NC_012988.1 1949060 1949521 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10339610, 12196152, 7715601, 9524269; Product type e : enzyme; cytochrome c-type biogenesis protein CycL precursor complement(1949060..1949521) Methylobacterium extorquens DM4 8192156 YP_003067616.1 CDS cycK NC_012988.1 1949518 1951518 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11744735, 7635817; Product type e : enzyme; cytochrome c-type biogenesis protein CycK; heme lyase complement(1949518..1951518) Methylobacterium extorquens DM4 8195238 YP_003067617.1 CDS cycJ NC_012988.1 1951565 1952098 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; cytochrome c-type biogenesis protein CycJ; periplasmic heme chaperone complement(1951565..1952098) Methylobacterium extorquens DM4 8195237 YP_003067618.1 CDS cycH NC_012988.1 1952261 1953844 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7715602, 8231805; Product type f : factor; cytochrome c-type biogenesis protein CycH complement(1952261..1953844) Methylobacterium extorquens DM4 8195236 YP_003067619.1 CDS METDI2067 NC_012988.1 1953991 1955406 R Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; integral membrane sensor signal transduction histidine kinase precursor complement(1953991..1955406) Methylobacterium extorquens DM4 8195235 YP_003067620.1 CDS METDI2068 NC_012988.1 1955403 1955660 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1955403..1955660) Methylobacterium extorquens DM4 8192157 YP_003067621.1 CDS METDI2069 NC_012988.1 1955793 1956470 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative phoP: DNA-binding response regulator in two-component regulatory system with PhoQ complement(1955793..1956470) Methylobacterium extorquens DM4 8192158 YP_003067622.1 CDS METDI2070 NC_012988.1 1956509 1957048 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1956509..1957048) Methylobacterium extorquens DM4 8192159 YP_003067623.1 CDS METDI2071 NC_012988.1 1957062 1957310 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1957062..1957310) Methylobacterium extorquens DM4 8192160 YP_003067624.1 CDS METDI2072 NC_012988.1 1957332 1957685 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1957332..1957685) Methylobacterium extorquens DM4 8192161 YP_003067625.1 CDS METDI2073 NC_012988.1 1957735 1958337 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1957735..1958337) Methylobacterium extorquens DM4 8192162 YP_003067626.1 CDS METDI2074 NC_012988.1 1958371 1958934 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1958371..1958934) Methylobacterium extorquens DM4 8192163 YP_003067627.1 CDS METDI2075 NC_012988.1 1959054 1959890 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1959054..1959890) Methylobacterium extorquens DM4 8192164 YP_003067628.1 CDS METDI2076 NC_012988.1 1959437 1960135 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1959437..1960135) Methylobacterium extorquens DM4 8192165 YP_003067629.1 CDS METDI2077 NC_012988.1 1960160 1964062 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1960160..1964062) Methylobacterium extorquens DM4 8192166 YP_003067630.1 CDS METDI2078 NC_012988.1 1964086 1964550 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620121; Product type pe : putative enzyme; putative phage cell wall peptidase complement(1964086..1964550) Methylobacterium extorquens DM4 8192167 YP_003067631.1 CDS METDI2079 NC_012988.1 1964558 1965451 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1964558..1965451) Methylobacterium extorquens DM4 8192168 YP_003067632.1 CDS METDI2080 NC_012988.1 1965462 1966103 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1965462..1966103) Methylobacterium extorquens DM4 8192169 YP_003067633.1 CDS METDI2081 NC_012988.1 1966115 1966744 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1966115..1966744) Methylobacterium extorquens DM4 8192170 YP_003067634.1 CDS METDI2082 NC_012988.1 1966741 1966971 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1966741..1966971) Methylobacterium extorquens DM4 8192171 YP_003067635.1 CDS METDI2083 NC_012988.1 1966968 1967300 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1966968..1967300) Methylobacterium extorquens DM4 8192172 YP_003067636.1 CDS METDI2084 NC_012988.1 1967297 1967680 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Phage major tail protein complement(1967297..1967680) Methylobacterium extorquens DM4 8192173 YP_003067637.1 CDS METDI2085 NC_012988.1 1967737 1968156 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1967737..1968156) Methylobacterium extorquens DM4 8192174 YP_003067638.1 CDS METDI2086 NC_012988.1 1968153 1968494 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1968153..1968494) Methylobacterium extorquens DM4 8192175 YP_003067639.1 CDS METDI2087 NC_012988.1 1968517 1969092 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1968517..1969092) Methylobacterium extorquens DM4 8192176 YP_003067640.1 CDS METDI2088 NC_012988.1 1969126 1969881 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Peptidase S1 and S6, chymotrypsin/Hap 1969126..1969881 Methylobacterium extorquens DM4 8192177 YP_003067641.1 CDS METDI2089 NC_012988.1 1970029 1970877 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 1970029..1970877 Methylobacterium extorquens DM4 8192178 YP_003067642.1 CDS METDI2090 NC_012988.1 1970884 1972149 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage major capsid protein complement(1970884..1972149) Methylobacterium extorquens DM4 8192179 YP_003067643.1 CDS METDI2091 NC_012988.1 1972182 1972652 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage prohead protease complement(1972182..1972652) Methylobacterium extorquens DM4 8192180 YP_003067644.1 CDS METDI2092 NC_012988.1 1972710 1973882 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7723020; Product type h : extrachromosomal origin; Phage portal protein, HK97 complement(1972710..1973882) Methylobacterium extorquens DM4 8192181 YP_003067645.1 CDS METDI2093 NC_012988.1 1973929 1975194 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1973929..1975194) Methylobacterium extorquens DM4 8192182 YP_003067646.1 CDS METDI2094 NC_012988.1 1975157 1975585 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1975157..1975585) Methylobacterium extorquens DM4 8192183 YP_003067648.1 CDS cobJ NC_012988.1 1976010 1976771 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2211521, 8226690; Product type e : enzyme; Precorrin-3B C(17)-methyltransferase (Precorrin-3 methyltransferase) (Precorrin-3 methylase) complement(1976010..1976771) Methylobacterium extorquens DM4 8192185 YP_003067649.1 CDS cobI NC_012988.1 1976768 1977565 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2211521; Product type e : enzyme; Precorrin-2 C(20)-methyltransferase (S-adenosyl-L-methionine--precorrin-2 methyltransferase) (SP2MT) complement(1976768..1977565) Methylobacterium extorquens DM4 8195190 YP_003067650.1 CDS cobH NC_012988.1 1977565 1978197 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11470433, 1732194, 2211521; Product type e : enzyme; Precorrin-8X methylmutase (Precorrin isomerase) (HBA synthase) complement(1977565..1978197) Methylobacterium extorquens DM4 8195189 YP_003067651.1 CDS cobG NC_012988.1 1978204 1979490 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2211521; Product type e : enzyme; precorrin-3B synthase complement(1978204..1979490) Methylobacterium extorquens DM4 8195188 YP_003067652.1 CDS cobN NC_012988.1 1979487 1982918 R with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN complement(1979487..1982918) Methylobacterium extorquens DM4 8195187 YP_003067653.1 CDS METDI2101 NC_012988.1 1982932 1983828 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1982932..1983828) Methylobacterium extorquens DM4 8192186 YP_003067654.1 CDS cobW NC_012988.1 1983825 1984859 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1655697; Product type e : enzyme; cobalamin biosynthesis protein CobW complement(1983825..1984859) Methylobacterium extorquens DM4 8192187 YP_003067655.1 CDS METDI2103 NC_012988.1 1984856 1985263 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1984856..1985263) Methylobacterium extorquens DM4 8195200 YP_003067656.1 CDS METDI2104 NC_012988.1 1985256 1986023 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1985256..1986023) Methylobacterium extorquens DM4 8192188 YP_003067657.1 CDS METDI2105 NC_012988.1 1986054 1986236 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein complement(1986054..1986236) Methylobacterium extorquens DM4 8192189 YP_003067658.1 CDS METDI2106 NC_012988.1 1986521 1986943 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1986521..1986943) Methylobacterium extorquens DM4 8195031 YP_003067659.1 CDS METDI2107 NC_012988.1 1986930 1987421 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12612613, 12694921, 9402023; Product type r : regulator; transcriptional regulator, MarR family complement(1986930..1987421) Methylobacterium extorquens DM4 8192191 YP_003067660.1 CDS cobP NC_012988.1 1987503 1988033 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1655696, 7635831; Product type e : enzyme; Bifunctional adenosylcobalamin biosynthesis protein cobP 1987503..1988033 Methylobacterium extorquens DM4 8192192 YP_003067661.1 CDS cobA NC_012988.1 1988033 1988635 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12080060, 1655697, 1917862, 2403541, 2644187, 7860601, 7916712; Product type e : enzyme; cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase 1988033..1988635 Methylobacterium extorquens DM4 8195194 YP_003067662.1 CDS fumC NC_012988.1 1989200 1990741 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1989200..1990741 Methylobacterium extorquens DM4 8195181 YP_003067663.1 CDS fae NC_012988.1 1990856 1991395 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; formaldehyde activating enzyme homolog complement(1990856..1991395) Methylobacterium extorquens DM4 8195459 YP_003067664.1 CDS METDI2112 NC_012988.1 1991576 1991857 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1991576..1991857 Methylobacterium extorquens DM4 8195353 YP_003067665.1 CDS METDI2113 NC_012988.1 1991883 1992329 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1991883..1992329) Methylobacterium extorquens DM4 8192193 YP_003067666.1 CDS METDI2114 NC_012988.1 1992550 1993434 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9169427, 9578475; Product type pe : putative enzyme; putative alpha/beta hydrolase, putative epoxide hydrolase 1992550..1993434 Methylobacterium extorquens DM4 8192194 YP_003067667.1 CDS METDI2115 NC_012988.1 1993730 1995811 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1993730..1995811 Methylobacterium extorquens DM4 8192195 YP_003067668.1 CDS METDI2116 NC_012988.1 1995846 1999157 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sensor hybrid histidine kinase with multiple PAS and response regulator receiver domains complement(1995846..1999157) Methylobacterium extorquens DM4 8192196 YP_003067669.1 CDS METDI2117 NC_012988.1 1999280 2000221 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1999280..2000221) Methylobacterium extorquens DM4 8192197 YP_003067670.1 CDS METDI2118 NC_012988.1 2000410 2001219 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator (AraC family) 2000410..2001219 Methylobacterium extorquens DM4 8192198 YP_003067671.1 CDS METDI2119 NC_012988.1 2001275 2003365 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2001275..2003365) Methylobacterium extorquens DM4 8192199 YP_003067672.1 CDS METDI2120 NC_012988.1 2003556 2006393 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2003556..2006393) Methylobacterium extorquens DM4 8192200 YP_003067673.1 CDS METDI2121 NC_012988.1 2006407 2007321 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2006407..2007321) Methylobacterium extorquens DM4 8192201 YP_003067674.1 CDS METDI2122 NC_012988.1 2007333 2008343 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16677824; Product type pe : putative enzyme; putative ATPase, MoxR-like protein complement(2007333..2008343) Methylobacterium extorquens DM4 8192202 YP_003067675.1 CDS METDI2123 NC_012988.1 2008540 2008974 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2008540..2008974 Methylobacterium extorquens DM4 8192203 YP_003067676.1 CDS METDI2124 NC_012988.1 2008971 2009552 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2008971..2009552 Methylobacterium extorquens DM4 8192204 YP_003067677.1 CDS METDI2125 NC_012988.1 2009549 2010229 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2009549..2010229 Methylobacterium extorquens DM4 8192205 YP_003067678.1 CDS METDI2126 NC_012988.1 2010298 2010555 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2010298..2010555 Methylobacterium extorquens DM4 8192206 YP_003067679.1 CDS METDI2127 NC_012988.1 2010552 2011826 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleotidyl transferase/polymerase 2010552..2011826 Methylobacterium extorquens DM4 8192207 YP_003067680.1 CDS atpC NC_012988.1 2011924 2012325 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(2011924..2012325) Methylobacterium extorquens DM4 8192208 YP_003067681.1 CDS METDI2129 NC_012988.1 2012352 2012603 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2012352..2012603) Methylobacterium extorquens DM4 8195118 YP_003067682.1 CDS atpD NC_012988.1 2012727 2014184 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(2012727..2014184) Methylobacterium extorquens DM4 8192209 YP_003067683.1 CDS atpG NC_012988.1 2014209 2015099 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(2014209..2015099) Methylobacterium extorquens DM4 8195119 YP_003067684.1 CDS atpA NC_012988.1 2015267 2016796 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(2015267..2016796) Methylobacterium extorquens DM4 8195121 YP_003067685.1 CDS METDI2133 NC_012988.1 2016871 2017440 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP synthase delta chain (atpH) complement(2016871..2017440) Methylobacterium extorquens DM4 8195116 YP_003067686.1 CDS hemH NC_012988.1 2017709 2018779 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11743193, 11743194; Product type e : enzyme; Ferrochelatase (Protoheme ferro-lyase) (Heme synthetase) complement(2017709..2018779) Methylobacterium extorquens DM4 8192210 YP_003067687.1 CDS METDI2135 NC_012988.1 2018971 2019942 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase 2018971..2019942 Methylobacterium extorquens DM4 8195553 YP_003067688.1 CDS METDI2136 NC_012988.1 2019950 2021467 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 5'-nucleotidase , 2'3'-cyclic-nucleotide 2'-phosphodiesterase 2019950..2021467 Methylobacterium extorquens DM4 8192211 YP_003067689.1 CDS ung NC_012988.1 2021635 2022339 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10984043; Product type e : enzyme; Uracil-DNA glycosylase (UDG) 2021635..2022339 Methylobacterium extorquens DM4 8192212 YP_003067690.1 CDS METDI2138 NC_012988.1 2022571 2023401 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12471500; hypothetical protein 2022571..2023401 Methylobacterium extorquens DM4 8196303 YP_003067691.1 CDS METDI2139 NC_012988.1 2023404 2024807 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12471500, 2152903; Product type pt : putative transporter; putative chromate transport protein ChrA; putative membrane protein 2023404..2024807 Methylobacterium extorquens DM4 8192213 YP_003067692.1 CDS METDI2140 NC_012988.1 2024950 2025147 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2024950..2025147) Methylobacterium extorquens DM4 8192214 YP_003067693.1 CDS METDI2141 NC_012988.1 2025281 2026183 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8525063; Product type pf : putative factor; putative cell-binding factor 2 precursor (Major antigen peb4A), cbf2 complement(2025281..2026183) Methylobacterium extorquens DM4 8192215 YP_003067694.1 CDS secA NC_012988.1 2026658 2029570 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; preprotein translocase subunit, ATPase 2026658..2029570 Methylobacterium extorquens DM4 8192216 YP_003067695.1 CDS ampC NC_012988.1 2029733 2030896 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10595535, 6795623, 7041115, 92212899, 97464439, 9819201, 99421326; Product type e : enzyme; beta-lactamase complement(2029733..2030896) Methylobacterium extorquens DM4 8196105 YP_003067696.1 CDS METDI2144 NC_012988.1 2031053 2031934 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2031053..2031934 Methylobacterium extorquens DM4 8195073 YP_003067697.1 CDS METDI2145 NC_012988.1 2031931 2032386 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9371440; Product type pe : putative enzyme; putative hydrolase, Nudix domain 2031931..2032386 Methylobacterium extorquens DM4 8192217 YP_003067698.1 CDS METDI2146 NC_012988.1 2032421 2033677 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Poly(3-hydroxybutyrate) depolymerase complement(2032421..2033677) Methylobacterium extorquens DM4 8192218 YP_003067699.1 CDS METDI2147 NC_012988.1 2033752 2034201 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2033752..2034201) Methylobacterium extorquens DM4 8192219 YP_003067700.1 CDS dnaQ NC_012988.1 2034408 2035118 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10217794; Product type e : enzyme; DNA polymerase III epsilon subunit complement(2034408..2035118) Methylobacterium extorquens DM4 8192220 YP_003067701.1 CDS coaE NC_012988.1 2035189 2035779 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; dephospho-CoA kinase (dephosphocoenzyme A kinase) complement(2035189..2035779) Methylobacterium extorquens DM4 8195310 YP_003067702.1 CDS METDI2150 NC_012988.1 2035806 2036642 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10739937, 3277621; Product type pe : putative enzyme; putative shikimate 5-dehydrogenase (aroE) complement(2035806..2036642) Methylobacterium extorquens DM4 8195180 YP_003067703.1 CDS METDI2151 NC_012988.1 2036671 2037696 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10229265, 11443104, 15919996, 9696746; Product type pt : putative transporter; putative cation efflux system protein complement(2036671..2037696) Methylobacterium extorquens DM4 8192221 YP_003067704.1 CDS METDI2152 NC_012988.1 2037711 2038325 R Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; Maf-like protein complement(2037711..2038325) Methylobacterium extorquens DM4 8192222 YP_003067705.1 CDS METDI2153 NC_012988.1 2038342 2039478 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2038342..2039478) Methylobacterium extorquens DM4 8192223 YP_003067706.1 CDS METDI2154 NC_012988.1 2039490 2040320 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2039490..2040320) Methylobacterium extorquens DM4 8192224 YP_003067707.1 CDS hemE NC_012988.1 2041068 2042180 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; uroporphyrinogen decarboxylase 2041068..2042180 Methylobacterium extorquens DM4 8192225 YP_003067708.1 CDS METDI2156 NC_012988.1 2042177 2042626 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Nudix hydrolase family protein, putative pyrophosphohydrolase 2042177..2042626 Methylobacterium extorquens DM4 8195551 YP_003067709.1 CDS METDI2157 NC_012988.1 2042607 2043059 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2042607..2043059 Methylobacterium extorquens DM4 8192226 YP_003067710.1 CDS METDI2158 NC_012988.1 2043146 2043487 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2043146..2043487 Methylobacterium extorquens DM4 8192227 YP_003067711.1 CDS hisG NC_012988.1 2043636 2044613 R long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase complement(2043636..2044613) Methylobacterium extorquens DM4 8192228 YP_003067712.1 CDS hisZ NC_012988.1 2044610 2045788 R May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit complement(2044610..2045788) Methylobacterium extorquens DM4 8195563 YP_003067713.1 CDS METDI2161 NC_012988.1 2045933 2046820 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase-like hydrolase, HAD-superfamily subfamily IIA hydrolase complement(2045933..2046820) Methylobacterium extorquens DM4 8192229 YP_003067714.1 CDS METDI2162 NC_012988.1 2046941 2047453 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2046941..2047453) Methylobacterium extorquens DM4 8192230 YP_003067715.1 CDS METDI2163 NC_012988.1 2047759 2051175 D Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein; acylglycerophosphoethanolamine acyltransferase 2047759..2051175 Methylobacterium extorquens DM4 8192231 YP_003067716.1 CDS METDI2164 NC_012988.1 2051452 2051721 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2051452..2051721 Methylobacterium extorquens DM4 8192232 YP_003067717.1 CDS pgpC NC_012988.1 2051765 2052028 D Evidence 2b : Function of strongly homologous gene; Product type pr : putative regulator; DNA-binding protein 2051765..2052028 Methylobacterium extorquens DM4 8192233 YP_003067718.1 CDS METDI2166 NC_012988.1 2052175 2052861 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2052175..2052861 Methylobacterium extorquens DM4 8195852 YP_003067719.1 CDS METDI2167 NC_012988.1 2052883 2053875 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2052883..2053875) Methylobacterium extorquens DM4 8192234 YP_003067720.1 CDS METDI2168 NC_012988.1 2053936 2054958 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2053936..2054958) Methylobacterium extorquens DM4 8192235 YP_003067721.1 CDS moaE NC_012988.1 2055118 2055570 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11135669, 12571227, 8514782, 93368423; Product type e : enzyme; molybdopterin synthase, large subunit 2055118..2055570 Methylobacterium extorquens DM4 8192236 YP_003067722.1 CDS METDI2170 NC_012988.1 2055663 2056835 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2055663..2056835 Methylobacterium extorquens DM4 8195706 YP_003067723.1 CDS mqo NC_012988.1 2056873 2058525 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2056873..2058525) Methylobacterium extorquens DM4 8192237 YP_003067724.1 CDS METDI2172 NC_012988.1 2058871 2060034 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2058871..2060034) Methylobacterium extorquens DM4 8195721 YP_003067725.1 CDS METDI2173 NC_012988.1 2060031 2062364 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2060031..2062364) Methylobacterium extorquens DM4 8192238 YP_003067726.1 CDS yehL NC_012988.1 2062361 2063461 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC superfamily protein complement(2062361..2063461) Methylobacterium extorquens DM4 8192239 YP_003067727.1 CDS METDI2175 NC_012988.1 2063458 2065041 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2063458..2065041) Methylobacterium extorquens DM4 8196359 YP_003067728.1 CDS METDI2176 NC_012988.1 2065041 2066408 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2065041..2066408) Methylobacterium extorquens DM4 8192240 YP_003067729.1 CDS zwf NC_012988.1 2066604 2068106 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2066604..2068106) Methylobacterium extorquens DM4 8192241 YP_003067730.1 CDS METDI2178 NC_012988.1 2068240 2068488 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2068240..2068488 Methylobacterium extorquens DM4 8196382 YP_003067731.1 CDS METDI2179 NC_012988.1 2068485 2068775 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2068485..2068775 Methylobacterium extorquens DM4 8192242 YP_003067732.1 CDS METDI2180 NC_012988.1 2068857 2069495 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2068857..2069495 Methylobacterium extorquens DM4 8192243 YP_003067733.1 CDS pyrF NC_012988.1 2071458 2072156 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2071458..2072156 Methylobacterium extorquens DM4 8192246 YP_003067734.1 CDS METDI2184 NC_012988.1 2072159 2072503 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2072159..2072503 Methylobacterium extorquens DM4 8195951 YP_003067735.1 CDS METDI2185 NC_012988.1 2072523 2073146 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, TetR family complement(2072523..2073146) Methylobacterium extorquens DM4 8192247 YP_003067736.1 CDS METDI2186 NC_012988.1 2073369 2073569 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2073369..2073569) Methylobacterium extorquens DM4 8192248 YP_003067737.1 CDS dut NC_012988.1 2073772 2074278 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(2073772..2074278) Methylobacterium extorquens DM4 8192249 YP_003067738.1 CDS METDI2188 NC_012988.1 2074375 2075148 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2074375..2075148 Methylobacterium extorquens DM4 8195319 YP_003067739.1 CDS METDI2189 NC_012988.1 2075153 2075686 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mutator protein MutT/NUDIX-family hydrolase 2075153..2075686 Methylobacterium extorquens DM4 8192250 YP_003067740.1 CDS METDI2190 NC_012988.1 2075913 2076599 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16926146; Product type pe : putative enzyme; putative carbonic anhydrase domain 2075913..2076599 Methylobacterium extorquens DM4 8192251 YP_003067741.1 CDS METDI2191 NC_012988.1 2076818 2077741 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729235; Product type pe : putative enzyme; putative CysQ protein (PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase) complement(2076818..2077741) Methylobacterium extorquens DM4 8192252 YP_003067742.1 CDS METDI2192 NC_012988.1 2077752 2077967 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2077752..2077967) Methylobacterium extorquens DM4 8192253 YP_003067743.1 CDS METDI2193 NC_012988.1 2078096 2078836 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2078096..2078836 Methylobacterium extorquens DM4 8192254 YP_003067744.1 CDS METDI2194 NC_012988.1 2079014 2081764 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; signal transduction histidine kinase with N-terminal phosphotransfer, CheW-like and C-terminal response regulator receiver domains 2079014..2081764 Methylobacterium extorquens DM4 8192255 YP_003067745.1 CDS cheW NC_012988.1 2081797 2082276 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11934495; Product type r : regulator; Chemotaxis signal transduction/oligomerization protein 2081797..2082276 Methylobacterium extorquens DM4 8192256 YP_003067746.1 CDS cheY NC_012988.1 2082297 2082719 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Chemotaxis response regulator receiver 2082297..2082719 Methylobacterium extorquens DM4 8195165 YP_003067747.1 CDS cheB NC_012988.1 2082786 2083934 D Evidence 2b : Function of strongly homologous gene; PubMedId : 3280143, 3510184, 89053899, 90008896, 93209955, 9687492, 99395068; Product type r : regulator; Chemotaxis response regulator protein-glutamate methylesterase 2082786..2083934 Methylobacterium extorquens DM4 8195166 YP_003067748.1 CDS cheR NC_012988.1 2083934 2084791 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11934495; Product type r : regulator; glutamate methyltransferase, chemotactic response regulator 2083934..2084791 Methylobacterium extorquens DM4 8195162 YP_003067749.1 CDS METDI2199 NC_012988.1 2084838 2085563 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidolyase/hydrolase/carboxylase subunit 2084838..2085563 Methylobacterium extorquens DM4 8195164 YP_003067750.1 CDS METDI2200 NC_012988.1 2085560 2086579 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidolyase/hydrolase/carboxylase subunit 2085560..2086579 Methylobacterium extorquens DM4 8192257 YP_003067751.1 CDS METDI2201 NC_012988.1 2086625 2087719 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8614629; Product type pe : putative enzyme; putative UV damage endonuclease 2086625..2087719 Methylobacterium extorquens DM4 8192258 YP_003067752.1 CDS METDI2202 NC_012988.1 2087840 2090557 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2087840..2090557 Methylobacterium extorquens DM4 8192259 YP_003067753.1 CDS METDI2203 NC_012988.1 2090733 2090918 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2090733..2090918 Methylobacterium extorquens DM4 8192260 YP_003067754.1 CDS METDI2204 NC_012988.1 2090949 2091389 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16926146; hypothetical protein complement(2090949..2091389) Methylobacterium extorquens DM4 8192261 YP_003067755.1 CDS METDI2205 NC_012988.1 2091705 2092343 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2091705..2092343 Methylobacterium extorquens DM4 8192262 YP_003067756.1 CDS meaD NC_012988.1 2092464 2093036 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12511515, 14734568; Product type e : enzyme; cobalamin adenosyltransferase, methylmalonyl-CoA mutase cofactor biosynthesis protein 2092464..2093036 Methylobacterium extorquens DM4 8192263 YP_003067757.1 CDS etfB NC_012988.1 2093199 2093948 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Electron transfer flavoprotein subunit beta (Beta-ETF) (Electron transfer flavoprotein small subunit) (ETFSS) 2093199..2093948 Methylobacterium extorquens DM4 8195678 YP_003067758.1 CDS etfA NC_012988.1 2094029 2094982 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15188393, 16926146, 8599534; Product type e : enzyme; electron transfer flavoprotein, NAD/FAD-binding domain and ETFP adenine nucleotide-binding domain-like 2094029..2094982 Methylobacterium extorquens DM4 8195335 YP_003067759.1 CDS hbdA NC_012988.1 2095141 2096022 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2687255, 8655474; Product type e : enzyme; 3-hydroxybutyryl-CoA dehydrogenase 2095141..2096022 Methylobacterium extorquens DM4 8195334 YP_003067760.1 CDS METDI2210 NC_012988.1 2096158 2096436 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2096158..2096436) Methylobacterium extorquens DM4 8195546 YP_003067761.1 CDS METDI2211 NC_012988.1 2096628 2097638 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NADPH quinone oxidoreductase complement(2096628..2097638) Methylobacterium extorquens DM4 8192264 YP_003067762.1 CDS METDI2212 NC_012988.1 2097635 2097889 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16208464; hypothetical protein complement(2097635..2097889) Methylobacterium extorquens DM4 8192265 YP_003067763.1 CDS upp NC_012988.1 2097993 2098643 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12037295; Product type e : enzyme; uracil phosphoribosyltransferase complement(2097993..2098643) Methylobacterium extorquens DM4 8192266 YP_003067764.1 CDS glgX NC_012988.1 2098740 2100833 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2975249, 8980629; Product type e : enzyme; glycosyl hydrolase (Debranching enzyme) complement(2098740..2100833) Methylobacterium extorquens DM4 8196305 YP_003067765.1 CDS otsA NC_012988.1 2100916 2102340 R Evidence 2b : Function of strongly homologous gene; PubMedId : 16052332, 17209814; Product type e : enzyme; alpha,alpha-trehalose-phosphate synthase (UDP-forming); osmoregulatory trehalose synthesis protein A complement(2100916..2102340) Methylobacterium extorquens DM4 8195492 YP_003067766.1 CDS METDI2216 NC_012988.1 2102871 2103350 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11097914; hypothetical protein 2102871..2103350 Methylobacterium extorquens DM4 8195814 YP_003067767.1 CDS METDI2217 NC_012988.1 2103347 2103769 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2103347..2103769 Methylobacterium extorquens DM4 8192267 YP_003067768.1 CDS METDI2218 NC_012988.1 2103766 2104152 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2103766..2104152 Methylobacterium extorquens DM4 8192268 YP_003067769.1 CDS METDI2219 NC_012988.1 2104217 2105053 D Evidence 5 : No homology to any previously reported sequences; PubMedId : 16926146; hypothetical protein 2104217..2105053 Methylobacterium extorquens DM4 8192269 YP_003067770.1 CDS hisS NC_012988.1 2105133 2106644 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2105133..2106644) Methylobacterium extorquens DM4 8192270 YP_003067771.1 CDS csaA NC_012988.1 2106728 2107099 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1435734; Product type f : factor; Secretion chaperone protein complement(2106728..2107099) Methylobacterium extorquens DM4 8195566 YP_003067772.1 CDS METDI2222 NC_012988.1 2107198 2107716 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2107198..2107716) Methylobacterium extorquens DM4 8195221 YP_003067773.1 CDS METDI2223 NC_012988.1 2107783 2109036 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator family complement(2107783..2109036) Methylobacterium extorquens DM4 8192271 YP_003067774.1 CDS secB NC_012988.1 2109325 2109831 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12475171, 14643199, 15128935, 21194699, 90361704, 91004235, 93304177, 9564; Product type f : factor; protein-export protein SecB complement(2109325..2109831) Methylobacterium extorquens DM4 8192272 YP_003067775.1 CDS METDI2225 NC_012988.1 2110293 2111012 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2110293..2111012 Methylobacterium extorquens DM4 8196106 YP_003067776.1 CDS METDI2226 NC_012988.1 2111025 2112296 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-bound lytic murein transglycosylase 2111025..2112296 Methylobacterium extorquens DM4 8192273 YP_003067777.1 CDS METDI2227 NC_012988.1 2112293 2113078 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative Smr protein/MutS2 C-terminal, damaged DNA binding, mismatch repair 2112293..2113078 Methylobacterium extorquens DM4 8192274 YP_003067778.1 CDS rho NC_012988.1 2113331 2114674 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 2113331..2114674 Methylobacterium extorquens DM4 8192275 YP_003067779.1 CDS poxB NC_012988.1 2114948 2116681 D catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 2114948..2116681 Methylobacterium extorquens DM4 8195991 YP_003067780.1 CDS METDI2230 NC_012988.1 2116794 2117714 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2116794..2117714) Methylobacterium extorquens DM4 8195879 YP_003067781.1 CDS METDI2231 NC_012988.1 2118021 2118767 R Evidence 2b : Function of strongly homologous gene; Product type m : membrane component; Membrane protein, TerC family complement(2118021..2118767) Methylobacterium extorquens DM4 8192276 YP_003067782.1 CDS METDI2232 NC_012988.1 2118784 2119713 R similar to YegS from E. coli; putative lipid kinase complement(2118784..2119713) Methylobacterium extorquens DM4 8192277 YP_003067783.1 CDS METDI2233 NC_012988.1 2120278 2121093 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2120278..2121093 Methylobacterium extorquens DM4 8192278 YP_003067784.1 CDS METDI2234 NC_012988.1 2121230 2122540 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2121230..2122540 Methylobacterium extorquens DM4 8192279 YP_003067785.1 CDS METDI2235 NC_012988.1 2122571 2123449 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acid phosphatase complement(2122571..2123449) Methylobacterium extorquens DM4 8192280 YP_003067786.1 CDS METDI2236 NC_012988.1 2123615 2124505 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2123615..2124505) Methylobacterium extorquens DM4 8192281 YP_003067787.1 CDS METDI2237 NC_012988.1 2124502 2124798 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; DNA-binding protein, putative transcriptional regulator complement(2124502..2124798) Methylobacterium extorquens DM4 8192282 YP_003067788.1 CDS METDI2238 NC_012988.1 2124829 2125209 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2124829..2125209) Methylobacterium extorquens DM4 8192283 YP_003067789.1 CDS dapD NC_012988.1 2125266 2126108 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9012664; Product type e : enzyme; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase complement(2125266..2126108) Methylobacterium extorquens DM4 8192284 YP_003067790.1 CDS METDI2240 NC_012988.1 2126271 2126738 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative cyclic nucleotide binding protein complement(2126271..2126738) Methylobacterium extorquens DM4 8195272 YP_003067791.1 CDS METDI2241 NC_012988.1 2126925 2127611 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8655513; Product type pr : putative regulator; putative two-component transcriptional regulator, winged helix family complement(2126925..2127611) Methylobacterium extorquens DM4 8192285 YP_003067792.1 CDS METDI2242 NC_012988.1 2127902 2128495 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2127902..2128495 Methylobacterium extorquens DM4 8192286 YP_003067793.1 CDS METDI2243 NC_012988.1 2128535 2129275 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enzyme with PLP-binding domain, putative alanine racemase complement(2128535..2129275) Methylobacterium extorquens DM4 8192287 YP_003067794.1 CDS leuS NC_012988.1 2129587 2132214 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; leucine tRNA synthetase 2129587..2132214 Methylobacterium extorquens DM4 8192288 YP_003067795.1 CDS trmE NC_012988.1 2132305 2133639 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2132305..2133639 Methylobacterium extorquens DM4 8195632 YP_003067796.1 CDS METDI2246 NC_012988.1 2133653 2134675 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2133653..2134675) Methylobacterium extorquens DM4 8196212 YP_003067797.1 CDS METDI2247 NC_012988.1 2135043 2135309 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2135043..2135309 Methylobacterium extorquens DM4 8192289 YP_003067798.1 CDS gidA NC_012988.1 2135483 2137357 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 2135483..2137357 Methylobacterium extorquens DM4 8192290 YP_003067799.1 CDS gidB NC_012988.1 2137323 2138027 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275; Product type e : enzyme; Methyltransferase gidB (Glucose-inhibited division protein B) 2137323..2138027 Methylobacterium extorquens DM4 8195484 YP_003067800.1 CDS parA NC_012988.1 2138024 2138884 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12603730, 9054507; Product type e : enzyme; chromosome partitioning protein, ATP-binding, nucleotide-binding 2138024..2138884 Methylobacterium extorquens DM4 8195485 YP_003067801.1 CDS parB NC_012988.1 2138918 2139814 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; chromosome-partitioning protein parB 2138918..2139814 Methylobacterium extorquens DM4 8195826 YP_003067802.1 CDS holA NC_012988.1 2139879 2140910 R required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(2139879..2140910) Methylobacterium extorquens DM4 8195827 YP_003067803.1 CDS METDI2253 NC_012988.1 2140921 2141469 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2140921..2141469) Methylobacterium extorquens DM4 8192291 YP_003067804.1 CDS METDI2254 NC_012988.1 2141873 2142217 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2141873..2142217 Methylobacterium extorquens DM4 8192292 YP_003067805.1 CDS METDI2255 NC_012988.1 2142350 2143453 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2142350..2143453 Methylobacterium extorquens DM4 8192293 YP_003067806.1 CDS METDI2256 NC_012988.1 2143460 2144404 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2143460..2144404) Methylobacterium extorquens DM4 8192294 YP_003067807.1 CDS METDI2257 NC_012988.1 2144422 2145360 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7916685; Product type pe : putative enzyme; putative cyclohexadienyl dehydrogenase (tyrC-like) complement(2144422..2145360) Methylobacterium extorquens DM4 8192295 YP_003067808.1 CDS hisC NC_012988.1 2145357 2146475 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(2145357..2146475) Methylobacterium extorquens DM4 8192296 YP_003067809.1 CDS METDI2259 NC_012988.1 2146590 2147087 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2146590..2147087) Methylobacterium extorquens DM4 8195559 YP_003067810.1 CDS METDI2260 NC_012988.1 2147234 2149468 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent siderophore receptor (putative ferrichrome outer membrane transporter) complement(2147234..2149468) Methylobacterium extorquens DM4 8192297 YP_003067811.1 CDS trkD NC_012988.1 2149740 2151746 R Evidence 2b : Function of strongly homologous gene; PubMedId : 89197799, 94042856, 99229748; Product type t : transporter; potassium uptake protein Kup complement(2149740..2151746) Methylobacterium extorquens DM4 8192298 YP_003067812.1 CDS ispG NC_012988.1 2152065 2153384 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2152065..2153384) Methylobacterium extorquens DM4 8196209 YP_003067813.1 CDS METDI2264 NC_012988.1 2153725 2154969 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2153725..2154969 Methylobacterium extorquens DM4 8195474 YP_003067814.1 CDS METDI2265 NC_012988.1 2155061 2156113 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2155061..2156113 Methylobacterium extorquens DM4 8192299 YP_003067815.1 CDS metF NC_012988.1 2156213 2157145 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10201405, 6356036; Product type e : enzyme; 5,10-methylenetetrahydrofolate reductase 2156213..2157145 Methylobacterium extorquens DM4 8192300 YP_003067816.1 CDS metH NC_012988.1 2157345 2161097 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 2157345..2161097 Methylobacterium extorquens DM4 8195682 YP_003067817.1 CDS METDI2268 NC_012988.1 2161241 2161456 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2161241..2161456 Methylobacterium extorquens DM4 8195684 YP_003067818.1 CDS METDI2269 NC_012988.1 2161550 2162752 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2161550..2162752) Methylobacterium extorquens DM4 8192301 YP_003067819.1 CDS METDI2270 NC_012988.1 2162960 2164012 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycoside hydrolase/deacetylase 2162960..2164012 Methylobacterium extorquens DM4 8192302 YP_003067820.1 CDS METDI2271 NC_012988.1 2164025 2164462 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2164025..2164462) Methylobacterium extorquens DM4 8192303 YP_003067821.1 CDS METDI2272 NC_012988.1 2164598 2164804 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2164598..2164804) Methylobacterium extorquens DM4 8192304 YP_003067822.1 CDS METDI2273 NC_012988.1 2165178 2166326 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative cytochrome c oxidase assembly protein 2165178..2166326 Methylobacterium extorquens DM4 8192305 YP_003067823.1 CDS METDI2274 NC_012988.1 2166609 2167289 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7495855; Product type pf : putative factor; putative hemolysin III, HlyIII family 2166609..2167289 Methylobacterium extorquens DM4 8192306 YP_003067824.1 CDS METDI2275 NC_012988.1 2167412 2167675 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2167412..2167675) Methylobacterium extorquens DM4 8192307 YP_003067825.1 CDS thiC NC_012988.1 2168113 2170005 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 2168113..2170005 Methylobacterium extorquens DM4 8195037 YP_003067826.1 CDS METDI2277 NC_012988.1 2170222 2170569 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2170222..2170569 Methylobacterium extorquens DM4 8196185 YP_003067827.1 CDS METDI2279 NC_012988.1 2170746 2171120 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1699845; Product type pr : putative regulator; putative flagellar protein FlaF complement(2170746..2171120) Methylobacterium extorquens DM4 8192309 YP_003067828.1 CDS METDI2280 NC_012988.1 2171298 2171537 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2171298..2171537 Methylobacterium extorquens DM4 8192310 YP_003067829.1 CDS METDI2281 NC_012988.1 2171662 2171802 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2171662..2171802) Methylobacterium extorquens DM4 8192311 YP_003067830.1 CDS METDI2282 NC_012988.1 2171986 2172312 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2171986..2172312) Methylobacterium extorquens DM4 8192312 YP_003067831.1 CDS METDI2283 NC_012988.1 2172548 2173117 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphohydrolase/phosphoesterase complement(2172548..2173117) Methylobacterium extorquens DM4 8192313 YP_003067832.1 CDS METDI2284 NC_012988.1 2173175 2174311 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative TonB family C-terminal domain protein complement(2173175..2174311) Methylobacterium extorquens DM4 8192314 YP_003067833.1 CDS exbD NC_012988.1 2174316 2174777 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1644779, 2670903, 88273230, 93302502; Product type m : membrane component; enterobactin uptake protein complement(2174316..2174777) Methylobacterium extorquens DM4 8192315 YP_003067834.1 CDS METDI2286 NC_012988.1 2174862 2175563 R Evidence 2b : Function of strongly homologous gene; Product type m : membrane component; membrane spanning protein in TonB-ExbB-ExbD complex complement(2174862..2175563) Methylobacterium extorquens DM4 8195339 YP_003067835.1 CDS METDI2287 NC_012988.1 2175635 2176117 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2175635..2176117) Methylobacterium extorquens DM4 8192316 YP_003067836.1 CDS ibpA NC_012988.1 2176685 2177116 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; small heat shock protein 2176685..2177116 Methylobacterium extorquens DM4 8192317 YP_003067837.1 CDS METDI2289 NC_012988.1 2177290 2177571 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2177290..2177571 Methylobacterium extorquens DM4 8195585 YP_003067838.1 CDS METDI2290 NC_012988.1 2177603 2178388 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2177603..2178388) Methylobacterium extorquens DM4 8192318 YP_003067839.1 CDS METDI2291 NC_012988.1 2178514 2179743 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11157937; Product type pe : putative enzyme; putative glycosyl transferase 2178514..2179743 Methylobacterium extorquens DM4 8192319 YP_003067840.1 CDS infC NC_012988.1 2179920 2180441 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2179920..2180441 Methylobacterium extorquens DM4 8192320 YP_003067841.1 CDS METDI2293 NC_012988.1 2180634 2182970 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2180634..2182970) Methylobacterium extorquens DM4 8195599 YP_003067842.1 CDS METDI2294 NC_012988.1 2183129 2184262 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15838019, 16934238; Product type pe : putative enzyme; putative glycosyl transferase complement(2183129..2184262) Methylobacterium extorquens DM4 8192321 YP_003067843.1 CDS rpmI NC_012988.1 2184717 2184920 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10094780, 3298224, 3542048, 6325158, 93085722; Product type s : structure; 50S ribosomal protein L35 2184717..2184920 Methylobacterium extorquens DM4 8192322 YP_003067844.1 CDS rplT NC_012988.1 2184973 2185338 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2184973..2185338 Methylobacterium extorquens DM4 8196042 YP_003067845.1 CDS pheS NC_012988.1 2185523 2186602 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2185523..2186602 Methylobacterium extorquens DM4 8196029 YP_003067846.1 CDS pheT NC_012988.1 2186667 2189090 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; phenylalanine tRNA synthetase, beta-subunit 2186667..2189090 Methylobacterium extorquens DM4 8195858 YP_003067847.1 CDS METDI2299 NC_012988.1 2189116 2189991 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2189116..2189991 Methylobacterium extorquens DM4 8195859 YP_003067848.1 CDS moeB NC_012988.1 2189939 2190766 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11463785, 88314906, 90148107, 8514782, 93368423; Product type e : enzyme; molybdopterin synthase sulfurylase complement(2189939..2190766) Methylobacterium extorquens DM4 8192323 YP_003067849.1 CDS dapE NC_012988.1 2191032 2192198 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2191032..2192198 Methylobacterium extorquens DM4 8195715 YP_003067850.1 CDS truA NC_012988.1 2192359 2193111 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2192359..2193111) Methylobacterium extorquens DM4 8195273 YP_003067851.1 CDS fmt NC_012988.1 2193125 2194054 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase complement(2193125..2194054) Methylobacterium extorquens DM4 8196280 YP_003067852.1 CDS def NC_012988.1 2194065 2194580 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; peptide deformylase complement(2194065..2194580) Methylobacterium extorquens DM4 8195434 YP_003067853.1 CDS METDI2305 NC_012988.1 2194836 2196122 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2194836..2196122) Methylobacterium extorquens DM4 8195284 YP_003067854.1 CDS recR NC_012988.1 2196237 2196842 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(2196237..2196842) Methylobacterium extorquens DM4 8192324 YP_003067855.1 CDS pck NC_012988.1 2197170 2198789 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 2197170..2198789 Methylobacterium extorquens DM4 8195975 YP_003067856.1 CDS METDI2308 NC_012988.1 2198836 2200113 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Fe-S containing enzyme (yfgB) complement(2198836..2200113) Methylobacterium extorquens DM4 8195834 YP_003067857.1 CDS METDI2309 NC_012988.1 2200230 2201969 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; bifunctional shikimate kinase (N-terminal) / dehydroquinate synthase (C-terminal) enzyme complement(2200230..2201969) Methylobacterium extorquens DM4 8192325 YP_003067858.1 CDS METDI2310 NC_012988.1 2202218 2202952 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator (helix-turn-helix structure) 2202218..2202952 Methylobacterium extorquens DM4 8192326 YP_003067859.1 CDS mdh NC_012988.1 2203303 2204265 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15188393, 16926146, 8550482; Product type e : enzyme; malate dehydrogenase 2203303..2204265 Methylobacterium extorquens DM4 8192327 YP_003067860.1 CDS sucC NC_012988.1 2204343 2205539 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10625475, 10671455, 9917402; Product type e : enzyme; succinyl-CoA synthetase, beta subunit 2204343..2205539 Methylobacterium extorquens DM4 8195675 YP_003067861.1 CDS sucD NC_012988.1 2205548 2206435 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; succinyl-CoA synthetase, alpha subunit 2205548..2206435 Methylobacterium extorquens DM4 8196167 YP_003067862.1 CDS sucA NC_012988.1 2206660 2209650 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 2206660..2209650 Methylobacterium extorquens DM4 8196169 YP_003067863.1 CDS sucB NC_012988.1 2209734 2211074 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2209734..2211074 Methylobacterium extorquens DM4 8196164 YP_003067864.1 CDS lpd NC_012988.1 2211363 2212766 D Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 2211363..2212766 Methylobacterium extorquens DM4 8196165 YP_003067865.1 CDS METDI2317 NC_012988.1 2212966 2214591 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; histidine kinase 2212966..2214591 Methylobacterium extorquens DM4 8195644 YP_003067866.1 CDS METDI2318 NC_012988.1 2214650 2215282 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2214650..2215282 Methylobacterium extorquens DM4 8192328 YP_003067867.1 CDS soxG NC_012988.1 2215264 2215893 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sarcosine oxidase, gamma subunit complement(2215264..2215893) Methylobacterium extorquens DM4 8192329 YP_003067868.1 CDS soxA NC_012988.1 2215886 2218915 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7543100; Product type pe : putative enzyme; sarcosine oxidase, alpha subunit complement(2215886..2218915) Methylobacterium extorquens DM4 8196132 YP_003067869.1 CDS soxD NC_012988.1 2218912 2219199 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7543100; Product type e : enzyme; sarcosine oxidase, delta subunit complement(2218912..2219199) Methylobacterium extorquens DM4 8196124 YP_003067870.1 CDS soxB NC_012988.1 2219317 2220567 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7692961, 8611516, 9485355; Product type e : enzyme; sarcosine oxidase beta subunit complement(2219317..2220567) Methylobacterium extorquens DM4 8196130 YP_003067871.1 CDS METDI2323 NC_012988.1 2220768 2221766 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9286980; Product type pr : putative regulator; transcriptional regulator, AraC family 2220768..2221766 Methylobacterium extorquens DM4 8196127 YP_003067872.1 CDS METDI2324 NC_012988.1 2221941 2222876 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidotransferase; glutamine amidotransferase class-II domain 2221941..2222876 Methylobacterium extorquens DM4 8192330 YP_003067873.1 CDS METDI2325 NC_012988.1 2222876 2223565 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative GXGXG-motif protein, glutamate synthase and formylmethanofuran dehydrogenase-like domain 2222876..2223565 Methylobacterium extorquens DM4 8192331 YP_003067874.1 CDS METDI2326 NC_012988.1 2223565 2224908 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; FMN-dependent dehydrogenase with conserved glutamate synthase region 2223565..2224908 Methylobacterium extorquens DM4 8192332 YP_003067875.1 CDS METDI2327 NC_012988.1 2224998 2226296 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356885, 18175924; Product type pe : putative enzyme; putative gamma-glutamylmethylamide synthetase; glutamine synthetase type III family 2224998..2226296 Methylobacterium extorquens DM4 8192333 YP_003067876.1 CDS METDI2328 NC_012988.1 2226486 2226995 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2226486..2226995 Methylobacterium extorquens DM4 8192334 YP_003067877.1 CDS METDI2330 NC_012988.1 2228008 2238864 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative heme peroxidase with hemolysin-type calcium-binding domain 2228008..2238864 Methylobacterium extorquens DM4 8192336 YP_003067878.1 CDS METDI2331 NC_012988.1 2238925 2240691 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10388672, 11467725, 2184029; Product type t : transporter; type I secretion system ATPase 2238925..2240691 Methylobacterium extorquens DM4 8192337 YP_003067879.1 CDS METDI2332 NC_012988.1 2240688 2242943 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2240688..2242943 Methylobacterium extorquens DM4 8192338 YP_003067880.1 CDS METDI2333 NC_012988.1 2242965 2244311 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; type I secretion membrane fusion protein, HlyD family 2242965..2244311 Methylobacterium extorquens DM4 8192339 YP_003067881.1 CDS METDI2334 NC_012988.1 2244555 2245022 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2244555..2245022 Methylobacterium extorquens DM4 8192340 YP_003067882.1 CDS METDI2335 NC_012988.1 2245072 2246193 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2245072..2246193 Methylobacterium extorquens DM4 8192341 YP_003067883.1 CDS METDI2336 NC_012988.1 2246186 2246854 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; two-component transcriptional regulator, LuxR family 2246186..2246854 Methylobacterium extorquens DM4 8192342 YP_003067884.1 CDS METDI2337 NC_012988.1 2247218 2248093 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Esterase/lipase-like protein complement(2247218..2248093) Methylobacterium extorquens DM4 8192343 YP_003067885.1 CDS METDI2338 NC_012988.1 2248193 2249002 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ubiE/COQ5 methyltransferase family enzyme complement(2248193..2249002) Methylobacterium extorquens DM4 8192344 YP_003067886.1 CDS METDI2339 NC_012988.1 2249658 2255471 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2249658..2255471 Methylobacterium extorquens DM4 8192345 YP_003067887.1 CDS METDI2340 NC_012988.1 2255468 2257555 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sensor hybrid histidine kinase with PAS and two responser regulator receiver domains 2255468..2257555 Methylobacterium extorquens DM4 8192346 YP_003067888.1 CDS METDI2341 NC_012988.1 2257826 2258695 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2257826..2258695) Methylobacterium extorquens DM4 8192347 YP_003067889.1 CDS METDI2342 NC_012988.1 2258799 2259692 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, LysR family 2258799..2259692 Methylobacterium extorquens DM4 8192348 YP_003067890.1 CDS METDI2345 NC_012988.1 2262156 2262554 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2262156..2262554) Methylobacterium extorquens DM4 8192351 YP_003067891.1 CDS METDI2346 NC_012988.1 2262680 2263570 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family 2262680..2263570 Methylobacterium extorquens DM4 8192352 YP_003067892.1 CDS METDI2347 NC_012988.1 2263626 2263808 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2263626..2263808) Methylobacterium extorquens DM4 8192353 YP_003067893.1 CDS ycaC NC_012988.1 2263918 2264580 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11714269, 3062312, 9782055; Product type pe : putative enzyme; putative enzyme with cysteine hydrolase domain complement(2263918..2264580) Methylobacterium extorquens DM4 8192354 YP_003067894.1 CDS METDI2349 NC_012988.1 2264674 2265630 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Zinc-containing alcohol dehydrogenase superfamily complement(2264674..2265630) Methylobacterium extorquens DM4 8196353 YP_003067895.1 CDS METDI2350 NC_012988.1 2265726 2266664 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family 2265726..2266664 Methylobacterium extorquens DM4 8192355 YP_003067896.1 CDS METDI2351 NC_012988.1 2267248 2267622 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2267248..2267622) Methylobacterium extorquens DM4 8192356 YP_003067897.1 CDS METDI2352 NC_012988.1 2268432 2269124 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2268432..2269124 Methylobacterium extorquens DM4 8192357 YP_003067898.1 CDS METDI2353 NC_012988.1 2269187 2270065 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family 2269187..2270065 Methylobacterium extorquens DM4 8192358 YP_003067899.1 CDS METDI2354 NC_012988.1 2270149 2270445 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2270149..2270445 Methylobacterium extorquens DM4 8192359 YP_003067900.1 CDS METDI2355 NC_012988.1 2270518 2270943 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2270518..2270943) Methylobacterium extorquens DM4 8192360 YP_003067901.1 CDS METDI2356 NC_012988.1 2270907 2271257 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2270907..2271257) Methylobacterium extorquens DM4 8192361 YP_003067902.1 CDS METDI2357 NC_012988.1 2271397 2272413 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADPH quinone oxidoreductase, Zinc-containing alcohol dehydrogenase superfamily complement(2271397..2272413) Methylobacterium extorquens DM4 8192362 YP_003067903.1 CDS METDI2358 NC_012988.1 2272441 2273301 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2272441..2273301) Methylobacterium extorquens DM4 8192363 YP_003067904.1 CDS METDI2359 NC_012988.1 2274014 2275738 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor histidine kinase, putative diguanylate cyclase (GGDEF) domain 2274014..2275738 Methylobacterium extorquens DM4 8192364 YP_003067905.1 CDS METDI2361 NC_012988.1 2276398 2276727 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2276398..2276727) Methylobacterium extorquens DM4 8192366 YP_003067906.1 CDS METDI2362 NC_012988.1 2276821 2281986 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidase-related protein complement(2276821..2281986) Methylobacterium extorquens DM4 8192367 YP_003067907.1 CDS ygfU NC_012988.1 2282629 2284029 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; transporter 2282629..2284029 Methylobacterium extorquens DM4 8192369 YP_003067908.1 CDS METDI2365 NC_012988.1 2284156 2284563 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2284156..2284563) Methylobacterium extorquens DM4 8196364 YP_003067909.1 CDS METDI2366 NC_012988.1 2284560 2285975 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(2284560..2285975) Methylobacterium extorquens DM4 8192370 YP_003067910.1 CDS METDI2367 NC_012988.1 2285972 2286175 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2285972..2286175) Methylobacterium extorquens DM4 8192371 YP_003067911.1 CDS METDI2368 NC_012988.1 2286278 2286958 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16540542; Product type pe : putative enzyme; putative isochorismatase family protein RutB (Pyrimidine utilization protein B) complement(2286278..2286958) Methylobacterium extorquens DM4 8192372 YP_003067912.1 CDS METDI2369 NC_012988.1 2287249 2287443 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2287249..2287443) Methylobacterium extorquens DM4 8192373 YP_003067913.1 CDS METDI2370 NC_012988.1 2287466 2288461 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2287466..2288461 Methylobacterium extorquens DM4 8192374 YP_003067914.1 CDS atzB NC_012988.1 2288487 2289851 D catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway.; hydroxydechloroatrazine ethylaminohydrolase 2288487..2289851 Methylobacterium extorquens DM4 8192375 YP_003067915.1 CDS METDI2372 NC_012988.1 2289851 2291455 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative methyl-galactoside transporter, ATP-binding component of sugar ABC transporter (mglA-like) 2289851..2291455 Methylobacterium extorquens DM4 8195122 YP_003067916.1 CDS METDI2373 NC_012988.1 2291514 2292608 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative L-arabinose transporter, membrane component of sugar ABC transporter (araH-like) 2291514..2292608 Methylobacterium extorquens DM4 8192376 YP_003067917.1 CDS METDI2374 NC_012988.1 2292605 2293531 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter protein, permease component 2292605..2293531 Methylobacterium extorquens DM4 8192377 YP_003067918.1 CDS METDI2375 NC_012988.1 2293697 2294836 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative ABC transporter (substrate-binding protein precursor) (tat pathway signal) 2293697..2294836 Methylobacterium extorquens DM4 8192378 YP_003067919.1 CDS METDI2376 NC_012988.1 2295010 2296167 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease component of sugar ABC transporter 2295010..2296167 Methylobacterium extorquens DM4 8192379 YP_003067920.1 CDS METDI2377 NC_012988.1 2296190 2297110 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative membrane component of sugar ABC transporter 2296190..2297110 Methylobacterium extorquens DM4 8192380 YP_003067921.1 CDS amiF NC_012988.1 2297120 2298148 D formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 2297120..2298148 Methylobacterium extorquens DM4 8192381 YP_003067922.1 CDS METDI2379 NC_012988.1 2298145 2298864 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Isochorismatase hydrolase family 2298145..2298864 Methylobacterium extorquens DM4 8195066 YP_003067923.1 CDS METDI2380 NC_012988.1 2298872 2300422 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-binding protein of sugar ABC transporter 2298872..2300422 Methylobacterium extorquens DM4 8192382 YP_003067924.1 CDS METDI2381 NC_012988.1 2300763 2301575 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2300763..2301575) Methylobacterium extorquens DM4 8192383 YP_003067925.1 CDS METDI2382 NC_012988.1 2301912 2302985 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; Basic membrane lipoprotein 2301912..2302985 Methylobacterium extorquens DM4 8192384 YP_003067926.1 CDS METDI2383 NC_012988.1 2303061 2303342 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2303061..2303342) Methylobacterium extorquens DM4 8192385 YP_003067927.1 CDS METDI2384 NC_012988.1 2303414 2303620 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2303414..2303620) Methylobacterium extorquens DM4 8192386 YP_003067928.1 CDS METDI2385 NC_012988.1 2303709 2305355 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Peptidase S15 complement(2303709..2305355) Methylobacterium extorquens DM4 8192387 YP_003067929.1 CDS METDI2386 NC_012988.1 2305345 2306166 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative creatininase (creatine amidohydrolase) complement(2305345..2306166) Methylobacterium extorquens DM4 8192388 YP_003067930.1 CDS METDI2387 NC_012988.1 2306163 2307722 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase) (Acyl-CoA synthetase) (putative fadD) complement(2306163..2307722) Methylobacterium extorquens DM4 8192389 YP_003067931.1 CDS METDI2388 NC_012988.1 2307762 2308349 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)H dehydrogenase (quione) complement(2307762..2308349) Methylobacterium extorquens DM4 8192390 YP_003067932.1 CDS METDI2389 NC_012988.1 2308346 2309734 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2308346..2309734) Methylobacterium extorquens DM4 8192391 YP_003067933.1 CDS METDI2390 NC_012988.1 2309736 2310707 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 2OG-Fe(II) oxygenase superfamily complement(2309736..2310707) Methylobacterium extorquens DM4 8192392 YP_003067934.1 CDS METDI2391 NC_012988.1 2310720 2311688 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter protein, periplasmic substrate-binding component precursor complement(2310720..2311688) Methylobacterium extorquens DM4 8192393 YP_003067935.1 CDS METDI2392 NC_012988.1 2311688 2312761 R Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; rieske 2Fe-2S family protein complement(2311688..2312761) Methylobacterium extorquens DM4 8192394 YP_003067936.1 CDS METDI2393 NC_012988.1 2312828 2313622 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease component of ABC transporter complement(2312828..2313622) Methylobacterium extorquens DM4 8192395 YP_003067937.1 CDS METDI2394 NC_012988.1 2313619 2314557 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ATP-binding component of ABC transporter complement(2313619..2314557) Methylobacterium extorquens DM4 8192396 YP_003067938.1 CDS METDI2395 NC_012988.1 2314566 2315552 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter protein, periplasmic substrate-binding component precursor complement(2314566..2315552) Methylobacterium extorquens DM4 8192397 YP_003067939.1 CDS METDI2396 NC_012988.1 2315879 2316784 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family 2315879..2316784 Methylobacterium extorquens DM4 8192398 YP_003067940.1 CDS METDI2397 NC_012988.1 2316864 2318243 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; cytosine deaminase-like protein 2316864..2318243 Methylobacterium extorquens DM4 8192399 YP_003067941.1 CDS METDI2398 NC_012988.1 2318538 2318786 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2318538..2318786 Methylobacterium extorquens DM4 8192400 YP_003067942.1 CDS METDI2399 NC_012988.1 2319049 2319279 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2319049..2319279 Methylobacterium extorquens DM4 8192401 YP_003067943.1 CDS METDI2400 NC_012988.1 2319461 2320384 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family 2319461..2320384 Methylobacterium extorquens DM4 8192402 YP_003067944.1 CDS guaD NC_012988.1 2320412 2321770 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; guanine deaminase complement(2320412..2321770) Methylobacterium extorquens DM4 8192403 YP_003067945.1 CDS METDI2402 NC_012988.1 2321767 2324547 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, molybdopterin-binding subunit complement(2321767..2324547) Methylobacterium extorquens DM4 8195541 YP_003067946.1 CDS METDI2403 NC_012988.1 2324544 2325359 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, FAD-binding subunit complement(2324544..2325359) Methylobacterium extorquens DM4 8192404 YP_003067947.1 CDS METDI2404 NC_012988.1 2325500 2326489 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2325500..2326489) Methylobacterium extorquens DM4 8192405 YP_003067948.1 CDS METDI2405 NC_012988.1 2326594 2327559 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ATP-binding protein of ABC family transporter complement(2326594..2327559) Methylobacterium extorquens DM4 8192406 YP_003067949.1 CDS METDI2406 NC_012988.1 2327556 2328464 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC family transporter permease protein complement(2327556..2328464) Methylobacterium extorquens DM4 8192407 YP_003067950.1 CDS METDI2407 NC_012988.1 2328454 2329308 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC family transporter substrate-binding protein complement(2328454..2329308) Methylobacterium extorquens DM4 8192408 YP_003067951.1 CDS METDI2408 NC_012988.1 2329509 2330126 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; flavin reductase domain protein, FMN-binding complement(2329509..2330126) Methylobacterium extorquens DM4 8192409 YP_003067952.1 CDS rutD NC_012988.1 2330158 2330940 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enzyme of alternative pyrimidine degradation pathway, putative alpha/beta hydrolase complement(2330158..2330940) Methylobacterium extorquens DM4 8192410 YP_003067953.1 CDS rutC NC_012988.1 2330945 2331337 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16540542; Product type e : enzyme; enzyme of alternative pyrimidine degradation pathway complement(2330945..2331337) Methylobacterium extorquens DM4 8196094 YP_003067954.1 CDS rutB NC_012988.1 2331350 2332096 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16540542; Product type e : enzyme; enzyme of alternative pyrimidine degradation pathway complement(2331350..2332096) Methylobacterium extorquens DM4 8196093 YP_003067955.1 CDS METDI2412 NC_012988.1 2332096 2333190 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative luciferase family protein, putative flavin-dependent oxidoreductase complement(2332096..2333190) Methylobacterium extorquens DM4 8196092 YP_003067956.1 CDS METDI2413 NC_012988.1 2333449 2334231 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, TetR/AcrR family complement(2333449..2334231) Methylobacterium extorquens DM4 8192411 YP_003067957.1 CDS allA NC_012988.1 2334218 2334715 R catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase complement(2334218..2334715) Methylobacterium extorquens DM4 8192412 YP_003067958.1 CDS METDI2415 NC_012988.1 2334712 2335551 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2334712..2335551) Methylobacterium extorquens DM4 8195070 YP_003067959.1 CDS METDI2416 NC_012988.1 2335591 2336826 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2335591..2336826) Methylobacterium extorquens DM4 8192413 YP_003067960.1 CDS METDI2417 NC_012988.1 2336961 2337893 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, LysR family 2336961..2337893 Methylobacterium extorquens DM4 8192414 YP_003067961.1 CDS METDI2418 NC_012988.1 2337924 2339336 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2337924..2339336) Methylobacterium extorquens DM4 8192415 YP_003067962.1 CDS METDI2419 NC_012988.1 2339573 2339965 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2339573..2339965 Methylobacterium extorquens DM4 8192416 YP_003067963.1 CDS METDI2420 NC_012988.1 2340024 2340359 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2340024..2340359 Methylobacterium extorquens DM4 8192417 YP_003067964.1 CDS METDI2422 NC_012988.1 2340757 2341749 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2340757..2341749 Methylobacterium extorquens DM4 8192418 YP_003067965.1 CDS METDI2423 NC_012988.1 2341998 2342981 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2341998..2342981 Methylobacterium extorquens DM4 8192419 YP_003067966.1 CDS METDI2424 NC_012988.1 2343128 2344381 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16926146; Product type pe : putative enzyme; putative diguanylate cyclase with GGDEF motif; putative membrane protein 2343128..2344381 Methylobacterium extorquens DM4 8192420 YP_003067967.1 CDS METDI2425 NC_012988.1 2344608 2345288 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane protein, OmpW family 2344608..2345288 Methylobacterium extorquens DM4 8192421 YP_003067968.1 CDS METDI2426 NC_012988.1 2345568 2345930 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2345568..2345930) Methylobacterium extorquens DM4 8192422 YP_003067969.1 CDS METDI2428 NC_012988.1 2346072 2346263 D Evidence 6 : Doubtful CDS; hypothetical protein 2346072..2346263 Methylobacterium extorquens DM4 8192423 YP_003067970.1 CDS METDI2429 NC_012988.1 2346677 2346973 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2346677..2346973 Methylobacterium extorquens DM4 8192424 YP_003067971.1 CDS METDI2430 NC_012988.1 2347283 2347540 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2347283..2347540) Methylobacterium extorquens DM4 8192425 YP_003067972.1 CDS ggt NC_012988.1 2347651 2349459 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2570061, 88106604; Product type e : enzyme; gamma-glutamyltranspeptidase 2347651..2349459 Methylobacterium extorquens DM4 8192426 YP_003067973.1 CDS METDI2432 NC_012988.1 2349456 2350382 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aminoglycoside phosphotransferase complement(2349456..2350382) Methylobacterium extorquens DM4 8195482 YP_003067974.1 CDS METDI2433 NC_012988.1 2350812 2351603 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16151217; Product type pe : putative enzyme; putative 1-acylglycerol-3-phosphate O-acyltransferase (plsC) 2350812..2351603 Methylobacterium extorquens DM4 8192427 YP_003067975.1 CDS METDI2434 NC_012988.1 2351693 2351977 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2351693..2351977 Methylobacterium extorquens DM4 8192428 YP_003067976.1 CDS METDI2435 NC_012988.1 2351931 2352260 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2351931..2352260 Methylobacterium extorquens DM4 8192429 YP_003067977.1 CDS metW NC_012988.1 2352318 2353007 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11479715, 9721288; Product type e : enzyme; MetW (putative cysthationine synthase) complement(2352318..2353007) Methylobacterium extorquens DM4 8192430 YP_003067978.1 CDS metX NC_012988.1 2353014 2354231 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11479715, 12951250, 9209059; Product type e : enzyme; homoserine O-acetyltransferase complement(2353014..2354231) Methylobacterium extorquens DM4 8195686 YP_003067979.1 CDS msrB NC_012988.1 2354635 2355138 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; methionine sulfoxide reductase (Peptide-methionine (R)-S-oxide reductase) 2354635..2355138 Methylobacterium extorquens DM4 8195687 YP_003067980.1 CDS msrA NC_012988.1 2355166 2355888 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Peptide methionine sulfoxide reductase msrA (Protein-methionine-S-oxide reductase) (Peptide Met(O) reductase) 2355166..2355888 Methylobacterium extorquens DM4 8195730 YP_003067981.1 CDS bfr NC_012988.1 2355934 2356431 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type c : carrier; bacterioferritin, an iron storage homoprotein complement(2355934..2356431) Methylobacterium extorquens DM4 8195727 YP_003067982.1 CDS METDI2441 NC_012988.1 2356472 2356723 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2356472..2356723) Methylobacterium extorquens DM4 8195140 YP_003067983.1 CDS METDI2442 NC_012988.1 2357104 2357967 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2357104..2357967) Methylobacterium extorquens DM4 8192431 YP_003067984.1 CDS METDI2443 NC_012988.1 2358081 2359181 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; Exopolysaccharide biosynthesis protein complement(2358081..2359181) Methylobacterium extorquens DM4 8192432 YP_003067985.1 CDS METDI2444 NC_012988.1 2359352 2360062 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2359352..2360062 Methylobacterium extorquens DM4 8192433 YP_003067986.1 CDS METDI2445 NC_012988.1 2360323 2361459 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2360323..2361459) Methylobacterium extorquens DM4 8192434 YP_003067987.1 CDS METDI2446 NC_012988.1 2361626 2362147 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2361626..2362147 Methylobacterium extorquens DM4 8192435 YP_003067988.1 CDS METDI2447 NC_012988.1 2362208 2362390 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2362208..2362390) Methylobacterium extorquens DM4 8192436 YP_003067989.1 CDS rpmG NC_012988.1 2362632 2362799 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(2362632..2362799) Methylobacterium extorquens DM4 8192437 YP_003067990.1 CDS panB NC_012988.1 2364454 2365278 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(2364454..2365278) Methylobacterium extorquens DM4 8196041 YP_003067991.1 CDS METDI2452 NC_012988.1 2365705 2366100 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; thioredoxin-related complement(2365705..2366100) Methylobacterium extorquens DM4 8195823 YP_003067992.1 CDS METDI2453 NC_012988.1 2366131 2366718 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2366131..2366718) Methylobacterium extorquens DM4 8192438 YP_003067993.1 CDS METDI2454 NC_012988.1 2366736 2367551 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2366736..2367551) Methylobacterium extorquens DM4 8192439 YP_003067994.1 CDS METDI2455 NC_012988.1 2367593 2368525 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallo-hydrolase/oxidoreductase complement(2367593..2368525) Methylobacterium extorquens DM4 8192440 YP_003067995.1 CDS METDI2456 NC_012988.1 2368708 2369286 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, TetR family 2368708..2369286 Methylobacterium extorquens DM4 8192441 YP_003067996.1 CDS METDI2457 NC_012988.1 2369313 2369609 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleotidyltransferase 2369313..2369609 Methylobacterium extorquens DM4 8192442 YP_003067997.1 CDS METDI2458 NC_012988.1 2369609 2369983 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2369609..2369983 Methylobacterium extorquens DM4 8192443 YP_003067998.1 CDS METDI2459 NC_012988.1 2370026 2371012 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14556637; Product type pe : putative enzyme; putative GTPase, putative CobW-like cobalamin biosynthesis protein 2370026..2371012 Methylobacterium extorquens DM4 8192444 YP_003067999.1 CDS METDI2460 NC_012988.1 2371240 2371332 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2371240..2371332) Methylobacterium extorquens DM4 8192445 YP_003068000.1 CDS METDI2461 NC_012988.1 2371466 2371717 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2371466..2371717) Methylobacterium extorquens DM4 8192446 YP_003068001.1 CDS METDI2462 NC_012988.1 2372304 2373731 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2372304..2373731 Methylobacterium extorquens DM4 8192447 YP_003068002.1 CDS METDI2463 NC_012988.1 2373728 2377105 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2373728..2377105 Methylobacterium extorquens DM4 8192448 YP_003068003.1 CDS METDI2464 NC_012988.1 2377206 2378654 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2377206..2378654 Methylobacterium extorquens DM4 8192449 YP_003068004.1 CDS METDI2465 NC_012988.1 2378651 2379673 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2378651..2379673 Methylobacterium extorquens DM4 8192450 YP_003068005.1 CDS METDI2466 NC_012988.1 2379798 2380268 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2379798..2380268 Methylobacterium extorquens DM4 8192451 YP_003068006.1 CDS METDI2467 NC_012988.1 2379807 2380193 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2379807..2380193) Methylobacterium extorquens DM4 8192452 YP_003068007.1 CDS METDI2468 NC_012988.1 2380402 2380953 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2380402..2380953) Methylobacterium extorquens DM4 8192453 YP_003068008.1 CDS lysA NC_012988.1 2381024 2382292 R Evidence 2b : Function of strongly homologous gene; PubMedId : 14343156, 6272062; Product type e : enzyme; diaminopimelate decarboxylase complement(2381024..2382292) Methylobacterium extorquens DM4 8192454 YP_003068009.1 CDS METDI2470 NC_012988.1 2382493 2382843 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2382493..2382843) Methylobacterium extorquens DM4 8195656 YP_003068010.1 CDS METDI2471 NC_012988.1 2382996 2383274 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2382996..2383274) Methylobacterium extorquens DM4 8192455 YP_003068011.1 CDS METDI2472 NC_012988.1 2383465 2384187 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2383465..2384187) Methylobacterium extorquens DM4 8192456 YP_003068012.1 CDS METDI2473 NC_012988.1 2384412 2385029 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2384412..2385029) Methylobacterium extorquens DM4 8192457 YP_003068013.1 CDS rnhB NC_012988.1 2385384 2386034 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; RNAse HII complement(2385384..2386034) Methylobacterium extorquens DM4 8192458 YP_003068014.1 CDS METDI2476 NC_012988.1 2386162 2387238 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase, group 1 complement(2386162..2387238) Methylobacterium extorquens DM4 8196004 YP_003068015.1 CDS METDI2477 NC_012988.1 2387359 2388171 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2387359..2388171) Methylobacterium extorquens DM4 8192459 YP_003068016.1 CDS sga NC_012988.1 2388834 2390042 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; serine-glyoxylate aminotransferase (SGAT) 2388834..2390042 Methylobacterium extorquens DM4 8192460 YP_003068017.1 CDS hprA NC_012988.1 2390323 2391267 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12055310, 1657886; Product type e : enzyme; Hydroxypyruvate reductase, NAD(P)H-dependent 2390323..2391267 Methylobacterium extorquens DM4 8196115 YP_003068018.1 CDS mtdA NC_012988.1 2391411 2392277 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; NADP-dependent methylene-tetrahydromethanopterin/methylene- tetrahydrofolate dehydrogenase 2391411..2392277 Methylobacterium extorquens DM4 8195574 YP_003068019.1 CDS fch NC_012988.1 2392371 2392997 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; methenyl tetrahydrofolate cyclohydrolase 2392371..2392997 Methylobacterium extorquens DM4 8195731 YP_003068020.1 CDS mtkA NC_012988.1 2393446 2394618 D catalyzes the formation of malyl-CoA from malate and CoA; malate--CoA ligase subunit beta 2393446..2394618 Methylobacterium extorquens DM4 8195358 YP_003068021.1 CDS mtkB NC_012988.1 2394641 2395531 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 2394641..2395531 Methylobacterium extorquens DM4 8195733 YP_003068022.1 CDS ppc NC_012988.1 2395731 2398499 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; phosphoenolpyruvate carboxylase 2395731..2398499 Methylobacterium extorquens DM4 8195734 YP_003068023.1 CDS mcl NC_012988.1 2398687 2399661 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15188393, 16856937, 16926146, 17548827; Product type e : enzyme; malyl-CoA lyase/beta-methylmalyl-CoA lyase 2398687..2399661 Methylobacterium extorquens DM4 8195881 YP_003068024.1 CDS METDI2486 NC_012988.1 2399731 2400297 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2399731..2400297) Methylobacterium extorquens DM4 8195667 YP_003068025.1 CDS METDI2487 NC_012988.1 2400593 2401468 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carboxymethylenebutenolidase precursor (dienelactone hydrolase) (tat pathway signal) 2400593..2401468 Methylobacterium extorquens DM4 8192461 YP_003068026.1 CDS METDI2488 NC_012988.1 2401476 2401853 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transcriptional coactivator/pterin dehydratase complement(2401476..2401853) Methylobacterium extorquens DM4 8192462 YP_003068027.1 CDS METDI2489 NC_012988.1 2402080 2403075 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter substrate binding protein (subunit A) 2402080..2403075 Methylobacterium extorquens DM4 8192463 YP_003068028.1 CDS METDI2490 NC_012988.1 2403115 2403849 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter permease component (subunit B) 2403115..2403849 Methylobacterium extorquens DM4 8192464 YP_003068029.1 CDS METDI2491 NC_012988.1 2403830 2404603 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ABC transporter ATP-binding protein (subunit C) 2403830..2404603 Methylobacterium extorquens DM4 8192465 YP_003068030.1 CDS METDI2492 NC_012988.1 2405310 2407115 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative PQQ-linked dehydrogenase precursor 2405310..2407115 Methylobacterium extorquens DM4 8192466 YP_003068031.1 CDS METDI2493 NC_012988.1 2407270 2407860 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1657873; Product type c : carrier; cytochrome c 2407270..2407860 Methylobacterium extorquens DM4 8192467 YP_003068032.1 CDS METDI2494 NC_012988.1 2407860 2408714 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative XoxJ-and MxaJ-like protein precursor 2407860..2408714 Methylobacterium extorquens DM4 8192468 YP_003068033.1 CDS folK NC_012988.1 2408820 2409296 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156, 9168622; Product type e : enzyme; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK) complement(2408820..2409296) Methylobacterium extorquens DM4 8192469 YP_003068034.1 CDS folB NC_012988.1 2409293 2409685 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156, 9168622; Product type e : enzyme; dihydroneopterin aldolase complement(2409293..2409685) Methylobacterium extorquens DM4 8195438 YP_003068035.1 CDS folP NC_012988.1 2409678 2410547 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156, 9168622; Product type e : enzyme; 7,8-dihydropteroate synthase (dihydropteroate synthase (DHPS), dihydropteroate pyrophosphorylase) complement(2409678..2410547) Methylobacterium extorquens DM4 8195435 YP_003068036.1 CDS METDI2498 NC_012988.1 2410642 2411007 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 9168622; Product type f : factor; Orf3, putative exported protein complement(2410642..2411007) Methylobacterium extorquens DM4 8195439 YP_003068037.1 CDS METDI2499 NC_012988.1 2410988 2411722 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 9168622; Product type f : factor; Orf4 complement(2410988..2411722) Methylobacterium extorquens DM4 8192470 YP_003068038.1 CDS pqqE NC_012988.1 2411719 2412873 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; pyrroloquinoline quinone biosynthesis protein PqqE complement(2411719..2412873) Methylobacterium extorquens DM4 8192471 YP_003068039.1 CDS pqqCD NC_012988.1 2412870 2413970 R Required in the synthesis of PPQ, but its exact function is unknown; pyrroloquinoline quinone biosynthesis protein PqqC complement(2412870..2413970) Methylobacterium extorquens DM4 8195891 YP_003068040.1 CDS pqqB NC_012988.1 2414137 2415036 R possibly involved in transport of pyrroloquinoline quinone transport; pyrroloquinoline quinone biosynthesis protein PqqB complement(2414137..2415036) Methylobacterium extorquens DM4 8195890 YP_003068041.1 CDS pqqA NC_012988.1 2415084 2415173 R Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis; probably provides the glutamate and tyrosine residues that are cross-linked and modified to form the coenzyme; coenzyme PQQ synthesis protein PqqA complement(2415084..2415173) Methylobacterium extorquens DM4 8195889 YP_003068042.1 CDS mxbM NC_012988.1 2415508 2416215 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type r : regulator; two-component transcriptional regulator, response regulator complement(2415508..2416215) Methylobacterium extorquens DM4 8195887 YP_003068043.1 CDS mxbD NC_012988.1 2416212 2417849 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type r : regulator; two-component transcriptional regulator, sensor kinase complement(2416212..2417849) Methylobacterium extorquens DM4 8195764 YP_003068044.1 CDS METDI2506 NC_012988.1 2417958 2418164 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2417958..2418164) Methylobacterium extorquens DM4 8195763 YP_003068045.1 CDS fhcC NC_012988.1 2418312 2419109 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formyltransferase/hydrolase complex Fhc subunit C complement(2418312..2419109) Methylobacterium extorquens DM4 8192472 YP_003068046.1 CDS fhcD NC_012988.1 2419106 2420041 R catalyzes the transfer of a formyl group from formylmethanofuran to tetrahydromethanopterin tetrahydromethanopterin; formylmethanofuran--tetrahydromethanopterin formyltransferase complement(2419106..2420041) Methylobacterium extorquens DM4 8195375 YP_003068047.1 CDS fhcA NC_012988.1 2420067 2421713 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formyltransferase/hydrolase complex Fhc subunit A complement(2420067..2421713) Methylobacterium extorquens DM4 8195376 YP_003068048.1 CDS fhcB NC_012988.1 2421707 2422795 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; Formyltransferase/hydrolase complex Fhc subunit B complement(2421707..2422795) Methylobacterium extorquens DM4 8195373 YP_003068049.1 CDS mptG NC_012988.1 2423224 2424222 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; ribofuranosylaminobenzene 5'-phosphate (RFAP) synthase 2423224..2424222 Methylobacterium extorquens DM4 8195374 YP_003068050.1 CDS mtdB NC_012988.1 2424333 2425226 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; NAD(P)-dependent methylene tetrahydromethanopterin dehydrogenase 2424333..2425226 Methylobacterium extorquens DM4 8195720 YP_003068051.1 CDS METDI2514 NC_012988.1 2425337 2426461 D Evidence 1c : Function experimentally demonstrated in the studied genus; hypothetical protein 2425337..2426461 Methylobacterium extorquens DM4 8195732 YP_003068052.1 CDS mch NC_012988.1 2426391 2427362 D catalyzes the reversible formation of methenyl-H(4)methanopterin from N(5)-formyl-H(4)methanopterin; N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase 2426391..2427362 Methylobacterium extorquens DM4 8192473 YP_003068053.1 CDS METDI2516 NC_012988.1 2427637 2428551 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; hypothetical protein 2427637..2428551 Methylobacterium extorquens DM4 8195666 YP_003068054.1 CDS METDI2517 NC_012988.1 2428548 2429417 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; hypothetical protein 2428548..2429417 Methylobacterium extorquens DM4 8192474 YP_003068055.1 CDS fae NC_012988.1 2429675 2430187 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 15632161; Product type e : enzyme; formaldehyde-activating enzyme 2429675..2430187 Methylobacterium extorquens DM4 8192475 YP_003068056.1 CDS METDI2519 NC_012988.1 2430327 2431022 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12055310; Product type e : enzyme; conserved HisA-related protein (Orf17) involved in tetrahydromethanopterin-dependent formaldehyde oxidation complement(2430327..2431022) Methylobacterium extorquens DM4 8195354 YP_003068057.1 CDS METDI2520 NC_012988.1 2431026 2432060 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; hypothetical protein 2431026..2432060 Methylobacterium extorquens DM4 8192476 YP_003068058.1 CDS METDI2522 NC_012988.1 2432315 2433415 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; Conserved MxaE-like protein of unknown function complement(2432315..2433415) Methylobacterium extorquens DM4 8192477 YP_003068059.1 CDS METDI2523 NC_012988.1 2433441 2433971 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; Conserved MxaD-like protein precursor of unknown function complement(2433441..2433971) Methylobacterium extorquens DM4 8192478 YP_003068060.1 CDS METDI2524 NC_012988.1 2434037 2434591 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; Conserved MxaD-like protein precursor of unknown function complement(2434037..2434591) Methylobacterium extorquens DM4 8192479 YP_003068061.1 CDS METDI2525 NC_012988.1 2434612 2435208 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; hypothetical protein complement(2434612..2435208) Methylobacterium extorquens DM4 8192480 YP_003068062.1 CDS METDI2526 NC_012988.1 2435266 2436840 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; hypothetical protein complement(2435266..2436840) Methylobacterium extorquens DM4 8192481 YP_003068063.1 CDS METDI2527 NC_012988.1 2436837 2437460 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; hypothetical protein complement(2436837..2437460) Methylobacterium extorquens DM4 8192482 YP_003068064.1 CDS METDI2528 NC_012988.1 2437457 2438167 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; hypothetical protein complement(2437457..2438167) Methylobacterium extorquens DM4 8192483 YP_003068065.1 CDS METDI2529 NC_012988.1 2438213 2438734 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2438213..2438734) Methylobacterium extorquens DM4 8192484 YP_003068066.1 CDS METDI2530 NC_012988.1 2438967 2440235 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2438967..2440235 Methylobacterium extorquens DM4 8192485 YP_003068067.1 CDS METDI2531 NC_012988.1 2440402 2441388 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2440402..2441388 Methylobacterium extorquens DM4 8192486 YP_003068068.1 CDS METDI2532 NC_012988.1 2441480 2441914 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2441480..2441914 Methylobacterium extorquens DM4 8192487 YP_003068069.1 CDS METDI2533 NC_012988.1 2441928 2442206 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2441928..2442206 Methylobacterium extorquens DM4 8192488 YP_003068070.1 CDS METDI2534 NC_012988.1 2442203 2442952 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATPase 2442203..2442952 Methylobacterium extorquens DM4 8192489 YP_003068071.1 CDS METDI2535 NC_012988.1 2442949 2443842 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 2442949..2443842 Methylobacterium extorquens DM4 8192490 YP_003068072.1 CDS METDI2536 NC_012988.1 2443853 2444482 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2443853..2444482 Methylobacterium extorquens DM4 8192491 YP_003068073.1 CDS METDI2538 NC_012988.1 2445024 2447543 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent receptor:IMP dehydrogenase/GMP reductase precursor 2445024..2447543 Methylobacterium extorquens DM4 8192492 YP_003068074.1 CDS METDI2539 NC_012988.1 2447861 2448262 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2447861..2448262 Methylobacterium extorquens DM4 8192493 YP_003068075.1 CDS METDI2540 NC_012988.1 2448465 2448824 D Evidence 6 : Doubtful CDS; hypothetical protein 2448465..2448824 Methylobacterium extorquens DM4 8192494 YP_003068076.1 CDS METDI2541 NC_012988.1 2448928 2450475 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative glycosyl transferase complement(2448928..2450475) Methylobacterium extorquens DM4 8192495 YP_003068077.1 CDS METDI2542 NC_012988.1 2450607 2451866 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; glycosyl transferase complement(2450607..2451866) Methylobacterium extorquens DM4 8192496 YP_003068078.1 CDS METDI2543 NC_012988.1 2452039 2452617 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative polysaccharide export protein complement(2452039..2452617) Methylobacterium extorquens DM4 8192497 YP_003068079.1 CDS METDI2544 NC_012988.1 2452838 2455252 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative succinoglycan biosynthesis transport protein exoP 2452838..2455252 Methylobacterium extorquens DM4 8192498 YP_003068080.1 CDS METDI2545 NC_012988.1 2455289 2455423 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2455289..2455423) Methylobacterium extorquens DM4 8192499 YP_003068081.1 CDS METDI2546 NC_012988.1 2455807 2456130 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15322138, 1698765, 2674903; hypothetical protein complement(2455807..2456130) Methylobacterium extorquens DM4 8192500 YP_003068082.1 CDS dnaX NC_012988.1 2456221 2458101 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; DNA polymerase III, tau and gamma subunits complement(2456221..2458101) Methylobacterium extorquens DM4 8192501 YP_003068083.1 CDS METDI2548 NC_012988.1 2458358 2458846 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2458358..2458846 Methylobacterium extorquens DM4 8195311 YP_003068084.1 CDS METDI2549 NC_012988.1 2458881 2459141 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2458881..2459141) Methylobacterium extorquens DM4 8192502 YP_003068085.1 CDS METDI2551 NC_012988.1 2460335 2462083 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative recombinase 2460335..2462083 Methylobacterium extorquens DM4 8192504 YP_003068086.1 CDS METDI2553 NC_012988.1 2462304 2463188 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2462304..2463188 Methylobacterium extorquens DM4 8192505 YP_003068087.1 CDS METDI2554 NC_012988.1 2463469 2464428 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2463469..2464428 Methylobacterium extorquens DM4 8192506 YP_003068088.1 CDS METDI2555 NC_012988.1 2464428 2464595 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2464428..2464595 Methylobacterium extorquens DM4 8192507 YP_003068089.1 CDS METDI2556 NC_012988.1 2464592 2465125 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2464592..2465125 Methylobacterium extorquens DM4 8192508 YP_003068090.1 CDS METDI2557 NC_012988.1 2465177 2465455 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2465177..2465455 Methylobacterium extorquens DM4 8192509 YP_003068091.1 CDS MEDTI5948 NC_012988.1 2466281 2467339 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2466281..2467339) Methylobacterium extorquens DM4 8192510 YP_003068092.1 CDS METDI2559 NC_012988.1 2467490 2468038 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase complement(2467490..2468038) Methylobacterium extorquens DM4 8190530 YP_003068093.1 CDS MEDTI5949 NC_012988.1 2468245 2470005 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2468245..2470005) Methylobacterium extorquens DM4 8192511 YP_003068094.1 CDS METDI2560 NC_012988.1 2470109 2471824 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative site-specific DNA methyltransferase complement(2470109..2471824) Methylobacterium extorquens DM4 8190531 YP_003068095.1 CDS METDI2561 NC_012988.1 2472351 2472590 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2472351..2472590 Methylobacterium extorquens DM4 8192512 YP_003068096.1 CDS METDI2562 NC_012988.1 2472987 2473517 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2472987..2473517) Methylobacterium extorquens DM4 8192513 YP_003068097.1 CDS METDI2563 NC_012988.1 2473739 2473981 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2473739..2473981 Methylobacterium extorquens DM4 8192514 YP_003068098.1 CDS METDI2564 NC_012988.1 2474041 2474328 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2474041..2474328 Methylobacterium extorquens DM4 8192515 YP_003068099.1 CDS METDI2565 NC_012988.1 2474416 2475039 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2474416..2475039 Methylobacterium extorquens DM4 8192516 YP_003068100.1 CDS METDI2566 NC_012988.1 2475169 2475498 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2475169..2475498 Methylobacterium extorquens DM4 8192517 YP_003068101.1 CDS METDI2567 NC_012988.1 2475613 2476194 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2475613..2476194 Methylobacterium extorquens DM4 8192518 YP_003068102.1 CDS MEDTI5950 NC_012988.1 2477164 2478210 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2477164..2478210 Methylobacterium extorquens DM4 8196236 YP_003068103.1 CDS METDI2569 NC_012988.1 2478314 2479420 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AFG1-family ATPase complement(2478314..2479420) Methylobacterium extorquens DM4 8190532 YP_003068104.1 CDS MEDTI5951 NC_012988.1 2479684 2479878 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2479684..2479878 Methylobacterium extorquens DM4 8192520 YP_003068105.1 CDS METDI2570 NC_012988.1 2480364 2482007 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator superfamily; putative oxalate/formate antiporter 2480364..2482007 Methylobacterium extorquens DM4 8190533 YP_003068106.1 CDS METDI2572 NC_012988.1 2482333 2483085 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2482333..2483085 Methylobacterium extorquens DM4 8192521 YP_003068107.1 CDS METDI2574 NC_012988.1 2483348 2483614 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2483348..2483614 Methylobacterium extorquens DM4 8192522 YP_003068108.1 CDS METDI2575 NC_012988.1 2483731 2484207 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2483731..2484207 Methylobacterium extorquens DM4 8192523 YP_003068109.1 CDS METDI2576 NC_012988.1 2484648 2486183 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA mismatch repair protein 2484648..2486183 Methylobacterium extorquens DM4 8192524 YP_003068110.1 CDS METDI2577 NC_012988.1 2486180 2487718 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA mismatch repair protein 2486180..2487718 Methylobacterium extorquens DM4 8192525 YP_003068111.1 CDS METDI2579 NC_012988.1 2488481 2488687 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2488481..2488687 Methylobacterium extorquens DM4 8192526 YP_003068112.1 CDS METDI2580 NC_012988.1 2488928 2491264 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2488928..2491264) Methylobacterium extorquens DM4 8192527 YP_003068113.1 CDS METDI2581 NC_012988.1 2491261 2491638 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2491261..2491638) Methylobacterium extorquens DM4 8192528 YP_003068114.1 CDS METDI2582 NC_012988.1 2492290 2492991 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative partitioning protein, putative ATPase 2492290..2492991 Methylobacterium extorquens DM4 8192529 YP_003068115.1 CDS METDI2583 NC_012988.1 2492988 2493398 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2492988..2493398 Methylobacterium extorquens DM4 8192530 YP_003068116.1 CDS METDI2584 NC_012988.1 2493475 2494719 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10613878, 18433868; Product type f : factor; replication initiation protein RepC complement(2493475..2494719) Methylobacterium extorquens DM4 8192531 YP_003068117.1 CDS METDI2585 NC_012988.1 2495104 2495337 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 2495104..2495337 Methylobacterium extorquens DM4 8192532 YP_003068118.1 CDS METDI2586 NC_012988.1 2495447 2495818 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 2495447..2495818 Methylobacterium extorquens DM4 8192533 YP_003068119.1 CDS MEDTI5952 NC_012988.1 2495841 2496047 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; hypothetical protein complement(2495841..2496047) Methylobacterium extorquens DM4 8192534 YP_003068120.1 CDS METDI2587 NC_012988.1 2496182 2496514 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative single-strand binding protein/primosomal replication protein complement(2496182..2496514) Methylobacterium extorquens DM4 8190534 YP_003068121.1 CDS repC NC_012988.1 2497115 2498278 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10613878, 18433868; Product type f : factor; replication initiation protein RepC complement(2497115..2498278) Methylobacterium extorquens DM4 8192535 YP_003068122.1 CDS repB NC_012988.1 2498541 2499539 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10613878, 18433868; Product type f : factor; replication protein B complement(2498541..2499539) Methylobacterium extorquens DM4 8195036 YP_003068123.1 CDS repA NC_012988.1 2499521 2500675 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12383728, 18433868; Product type f : factor; replication protein A complement(2499521..2500675) Methylobacterium extorquens DM4 8195980 YP_003068124.1 CDS METDI2591 NC_012988.1 2500951 2502123 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; integrase/recombinase protein complement(2500951..2502123) Methylobacterium extorquens DM4 8195979 YP_003068125.1 CDS METDI2592 NC_012988.1 2502137 2503225 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2502137..2503225) Methylobacterium extorquens DM4 8192536 YP_003068126.1 CDS METDI2593 NC_012988.1 2503222 2503659 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; plasmid stability protein complement(2503222..2503659) Methylobacterium extorquens DM4 8192537 YP_003068127.1 CDS METDI2594 NC_012988.1 2503656 2503934 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative prevent-host-death family protein, putative antitoxin of toxin-antitoxin system complement(2503656..2503934) Methylobacterium extorquens DM4 8192538 YP_003068128.1 CDS METDI2595 NC_012988.1 2504056 2504355 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative prevent-host-death family protein 2504056..2504355 Methylobacterium extorquens DM4 8192539 YP_003068129.1 CDS METDI2596 NC_012988.1 2504902 2506023 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2504902..2506023 Methylobacterium extorquens DM4 8192540 YP_003068130.1 CDS METDI2597 NC_012988.1 2505901 2507145 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2505901..2507145) Methylobacterium extorquens DM4 8192541 YP_003068131.1 CDS tniB NC_012988.1 2507142 2508020 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; ATP-binding protein TniB complement(2507142..2508020) Methylobacterium extorquens DM4 8192542 YP_003068132.1 CDS METDI2599 NC_012988.1 2508022 2509680 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi29, ISNCY family complement(2508022..2509680) Methylobacterium extorquens DM4 8196202 YP_003068133.1 CDS METDI2601 NC_012988.1 2509956 2510882 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2509956..2510882 Methylobacterium extorquens DM4 8192543 YP_003068134.1 CDS METDI2602 NC_012988.1 2510882 2512393 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2510882..2512393 Methylobacterium extorquens DM4 8192544 YP_003068135.1 CDS METDI2603 NC_012988.1 2512606 2513814 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AAA ATPase 2512606..2513814 Methylobacterium extorquens DM4 8192545 YP_003068136.1 CDS METDI2604 NC_012988.1 2513804 2516332 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2513804..2516332 Methylobacterium extorquens DM4 8192546 YP_003068137.1 CDS METDI2605 NC_012988.1 2516450 2517640 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2516450..2517640 Methylobacterium extorquens DM4 8192547 YP_003068138.1 CDS METDI2606 NC_012988.1 2517708 2518358 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2517708..2518358 Methylobacterium extorquens DM4 8192548 YP_003068139.1 CDS METDI2607 NC_012988.1 2518364 2519320 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2518364..2519320 Methylobacterium extorquens DM4 8192549 YP_003068140.1 CDS METDI2608 NC_012988.1 2520413 2520814 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative caspase-like protease 2520413..2520814 Methylobacterium extorquens DM4 8192550 YP_003068141.1 CDS METDI2609 NC_012988.1 2520875 2521213 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2520875..2521213) Methylobacterium extorquens DM4 8192551 YP_003068142.1 CDS METDI2610 NC_012988.1 2521291 2522187 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2521291..2522187) Methylobacterium extorquens DM4 8192552 YP_003068143.1 CDS METDI2611 NC_012988.1 2522287 2522628 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 2522287..2522628 Methylobacterium extorquens DM4 8192553 YP_003068144.1 CDS METDI2612 NC_012988.1 2522625 2523128 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2522625..2523128 Methylobacterium extorquens DM4 8192554 YP_003068145.1 CDS METDI2613 NC_012988.1 2523189 2523386 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2523189..2523386 Methylobacterium extorquens DM4 8192555 YP_003068146.1 CDS METDI2614 NC_012988.1 2523456 2524157 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2523456..2524157 Methylobacterium extorquens DM4 8192556 YP_003068147.1 CDS METDI2615 NC_012988.1 2524546 2524857 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2524546..2524857) Methylobacterium extorquens DM4 8192557 YP_003068148.1 CDS MEDTI5953 NC_012988.1 2525518 2525736 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2525518..2525736) Methylobacterium extorquens DM4 8192558 YP_003068149.1 CDS glnA NC_012988.1 2525900 2527309 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2882477; Product type e : enzyme; glutamine synthetase, type I 2525900..2527309 Methylobacterium extorquens DM4 8190535 YP_003068150.1 CDS METDI2617 NC_012988.1 2527333 2528214 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2527333..2528214) Methylobacterium extorquens DM4 8195496 YP_003068151.1 CDS METDI2618 NC_012988.1 2528211 2529137 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative conjugal transfer antirestriction protein complement(2528211..2529137) Methylobacterium extorquens DM4 8192559 YP_003068152.1 CDS METDI2619 NC_012988.1 2529487 2530074 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2529487..2530074) Methylobacterium extorquens DM4 8192560 YP_003068153.1 CDS METDI2621 NC_012988.1 2530468 2530794 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2530468..2530794) Methylobacterium extorquens DM4 8192561 YP_003068154.1 CDS METDI2622 NC_012988.1 2530791 2531009 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2530791..2531009) Methylobacterium extorquens DM4 8192562 YP_003068155.1 CDS METDI2623 NC_012988.1 2531039 2531242 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2531039..2531242) Methylobacterium extorquens DM4 8192563 YP_003068156.1 CDS METDI2624 NC_012988.1 2531246 2532118 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2531246..2532118) Methylobacterium extorquens DM4 8192564 YP_003068157.1 CDS METDI2625 NC_012988.1 2532115 2532588 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2532115..2532588) Methylobacterium extorquens DM4 8192565 YP_003068158.1 CDS METDI2626 NC_012988.1 2532675 2534357 R ParB family; plasmid partitioning protein complement(2532675..2534357) Methylobacterium extorquens DM4 8192566 YP_003068159.1 CDS METDI2627 NC_012988.1 2534608 2539704 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA adenine methyltransferase; putative methylase and helicase domains complement(2534608..2539704) Methylobacterium extorquens DM4 8192567 YP_003068160.1 CDS METDI2628 NC_012988.1 2539809 2540003 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2539809..2540003) Methylobacterium extorquens DM4 8192568 YP_003068161.1 CDS METDI2629 NC_012988.1 2540020 2540622 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2540020..2540622) Methylobacterium extorquens DM4 8192569 YP_003068162.1 CDS METDI2630 NC_012988.1 2540914 2541207 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2540914..2541207) Methylobacterium extorquens DM4 8192570 YP_003068163.1 CDS METDI2631 NC_012988.1 2541239 2541901 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2541239..2541901) Methylobacterium extorquens DM4 8192571 YP_003068164.1 CDS METDI2632 NC_012988.1 2541941 2543734 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2541941..2543734) Methylobacterium extorquens DM4 8192572 YP_003068165.1 CDS METDI2633 NC_012988.1 2543731 2544162 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2543731..2544162) Methylobacterium extorquens DM4 8192573 YP_003068166.1 CDS METDI2634 NC_012988.1 2544316 2544618 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2544316..2544618) Methylobacterium extorquens DM4 8192574 YP_003068167.1 CDS METDI2635 NC_012988.1 2544849 2545142 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2544849..2545142) Methylobacterium extorquens DM4 8192575 YP_003068168.1 CDS METDI2636 NC_012988.1 2545139 2545552 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2545139..2545552) Methylobacterium extorquens DM4 8192576 YP_003068169.1 CDS METDI2637 NC_012988.1 2545685 2546611 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2545685..2546611) Methylobacterium extorquens DM4 8192577 YP_003068170.1 CDS METDI2638 NC_012988.1 2546816 2546992 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2546816..2546992) Methylobacterium extorquens DM4 8192578 YP_003068171.1 CDS METDI2640 NC_012988.1 2547541 2548344 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2547541..2548344) Methylobacterium extorquens DM4 8192579 YP_003068172.1 CDS METDI2641 NC_012988.1 2548347 2549081 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2548347..2549081) Methylobacterium extorquens DM4 8192580 YP_003068173.1 CDS modC NC_012988.1 2549173 2549865 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7665460, 8564363, 87194564, 89155423, 93368423; Product type t : transporter; ABC transporter, ATPase; molybdate transporter complement(2549173..2549865) Methylobacterium extorquens DM4 8192581 YP_003068174.1 CDS modB NC_012988.1 2549906 2550574 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3553151, 7665460, 8564363, 89155423, 90148107, 93368423; Product type t : transporter; ABC transporter, permease; molybdate transporter complement(2549906..2550574) Methylobacterium extorquens DM4 8195713 YP_003068175.1 CDS METDI2644 NC_012988.1 2550590 2551414 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, periplasmic protein; molybdate transporter complement(2550590..2551414) Methylobacterium extorquens DM4 8195710 YP_003068176.1 CDS METDI2645 NC_012988.1 2551651 2552604 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10564479; Product type pr : putative regulator; putative regulator; putative molybdate and DNA-binding domains, excisionase family protein 2551651..2552604 Methylobacterium extorquens DM4 8192582 YP_003068177.1 CDS METDI2646 NC_012988.1 2552812 2553660 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative universal stress protein UspA complement(2552812..2553660) Methylobacterium extorquens DM4 8192583 YP_003068178.1 CDS METDI2647 NC_012988.1 2553672 2554958 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sulfate transporter/antisigma-factor antagonist, major facilitator superfamily complement(2553672..2554958) Methylobacterium extorquens DM4 8192584 YP_003068179.1 CDS METDI2651 NC_012988.1 2557645 2558910 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 1938878, 9274009; Product type e : enzyme; transposase of IS1354, IS256 family complement(2557645..2558910) Methylobacterium extorquens DM4 8192587 YP_003068180.1 CDS METDI2654 NC_012988.1 2560108 2561211 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9274009; Product type e : enzyme; transposase of IS1357, IS701 family 2560108..2561211 Methylobacterium extorquens DM4 8192590 YP_003068181.1 CDS dcmR NC_012988.1 2561469 2562266 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 1938878; Product type r : regulator; transcriptional repressor of DCM dehalogenase complement(2561469..2562266) Methylobacterium extorquens DM4 8192591 YP_003068182.1 CDS dcmA NC_012988.1 2563050 2563823 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 11238968, 2104602, 8206823; Product type e : enzyme; dichloromethane dehalogenase (DCM dehalogenase) 2563050..2563823 Methylobacterium extorquens DM4 8195277 YP_003068183.1 CDS METDI2657 NC_012988.1 2563926 2564987 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2563926..2564987 Methylobacterium extorquens DM4 8195276 YP_003068184.1 CDS METDI2658 NC_012988.1 2565022 2565600 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2565022..2565600 Methylobacterium extorquens DM4 8192592 YP_003068185.1 CDS METDI2659 NC_012988.1 2565711 2566976 R Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 9274009; Product type e : enzyme; transposase of IS1354, IS256 family complement(2565711..2566976) Methylobacterium extorquens DM4 8192593 YP_003068186.1 CDS METDI2661 NC_012988.1 2567488 2568453 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1310791, 3174633; Product type e : enzyme; transposase of ISMdi13, IS256 family (ORF2) complement(2567488..2568453) Methylobacterium extorquens DM4 8192595 YP_003068187.1 CDS METDI2662 NC_012988.1 2568405 2568770 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi13, IS256 family (ORF1) complement(2568405..2568770) Methylobacterium extorquens DM4 8192596 YP_003068188.1 CDS METDI2664 NC_012988.1 2569301 2570218 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nitrilase/amidohydrolase complement(2569301..2570218) Methylobacterium extorquens DM4 8192598 YP_003068189.1 CDS METDI2665 NC_012988.1 2570346 2571059 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(2570346..2571059) Methylobacterium extorquens DM4 8192599 YP_003068190.1 CDS METDI2666 NC_012988.1 2571056 2572207 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative coenzyme A transferase; putative formyl-CoA transferase complement(2571056..2572207) Methylobacterium extorquens DM4 8192600 YP_003068191.1 CDS METDI2667 NC_012988.1 2572757 2573125 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2572757..2573125) Methylobacterium extorquens DM4 8192601 YP_003068192.1 CDS METDI2668 NC_012988.1 2573315 2574484 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2573315..2574484 Methylobacterium extorquens DM4 8192602 YP_003068193.1 CDS METDI2670 NC_012988.1 2575436 2576701 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(2575436..2576701) Methylobacterium extorquens DM4 8192603 YP_003068194.1 CDS bioD NC_012988.1 2576698 2577330 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(2576698..2577330) Methylobacterium extorquens DM4 8192604 YP_003068195.1 CDS METDI2672 NC_012988.1 2577327 2578331 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative bifunctional enzyme, phosphoglycerate mutase and PLP-dependent aminotransferase domains complement(2577327..2578331) Methylobacterium extorquens DM4 8195143 YP_003068196.1 CDS METDI2673 NC_012988.1 2578741 2578917 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2578741..2578917) Methylobacterium extorquens DM4 8192605 YP_003068197.1 CDS METDI2674 NC_012988.1 2579887 2580144 D Evidence 6 : Doubtful CDS; hypothetical protein 2579887..2580144 Methylobacterium extorquens DM4 8192606 YP_003068198.1 CDS METDI2675 NC_012988.1 2580380 2580688 D Evidence 6 : Doubtful CDS; hypothetical protein 2580380..2580688 Methylobacterium extorquens DM4 8192607 YP_003068199.1 CDS METDI2676 NC_012988.1 2581383 2581637 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2581383..2581637 Methylobacterium extorquens DM4 8192608 YP_003068200.1 CDS METDI2677 NC_012988.1 2581654 2581887 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2581654..2581887) Methylobacterium extorquens DM4 8192609 YP_003068201.1 CDS METDI2679 NC_012988.1 2582625 2582858 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2582625..2582858) Methylobacterium extorquens DM4 8192610 YP_003068202.1 CDS METDI2680 NC_012988.1 2582910 2583575 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2582910..2583575) Methylobacterium extorquens DM4 8192611 YP_003068203.1 CDS METDI2682 NC_012988.1 2584162 2585910 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2584162..2585910) Methylobacterium extorquens DM4 8192612 YP_003068204.1 CDS METDI2685 NC_012988.1 2587552 2588160 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase 2587552..2588160 Methylobacterium extorquens DM4 8192614 YP_003068205.1 CDS METDI2686 NC_012988.1 2588338 2589534 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2588338..2589534 Methylobacterium extorquens DM4 8192615 YP_003068206.1 CDS METDI2687 NC_012988.1 2589545 2590909 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor and regulator, histidine kinase and CheY-like receiver domains 2589545..2590909 Methylobacterium extorquens DM4 8192616 YP_003068207.1 CDS METDI2688 NC_012988.1 2590932 2591255 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2590932..2591255) Methylobacterium extorquens DM4 8192617 YP_003068208.1 CDS METDI2689 NC_012988.1 2591568 2592236 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transglutaminase family protein cysteine peptidase precursor complement(2591568..2592236) Methylobacterium extorquens DM4 8192618 YP_003068209.1 CDS METDI2690 NC_012988.1 2592480 2592899 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15808744, 2985285; Product type e : enzyme; thioesterase/thiol ester dehydrase-isomerase domain protein 2592480..2592899 Methylobacterium extorquens DM4 8192619 YP_003068210.1 CDS METDI2691 NC_012988.1 2592935 2593840 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; alpha/beta hydrolase protein precursor complement(2592935..2593840) Methylobacterium extorquens DM4 8192620 YP_003068211.1 CDS METDI2692 NC_012988.1 2593904 2594833 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2593904..2594833) Methylobacterium extorquens DM4 8192621 YP_003068212.1 CDS METDI2693 NC_012988.1 2595057 2597237 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative molybdopterin oxidoreductase 2595057..2597237 Methylobacterium extorquens DM4 8192622 YP_003068213.1 CDS yejF NC_012988.1 2597344 2598972 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; oligopeptide transport protein (ABC superfamily, atp_bind) 2597344..2598972 Methylobacterium extorquens DM4 8192623 YP_003068214.1 CDS deoB NC_012988.1 2598976 2600196 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9692190; Product type e : enzyme; phosphopentomutase 2598976..2600196 Methylobacterium extorquens DM4 8196362 YP_003068215.1 CDS METDI2696 NC_012988.1 2600485 2602137 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(2600485..2602137) Methylobacterium extorquens DM4 8195287 YP_003068216.1 CDS METDI2697 NC_012988.1 2602362 2602640 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2602362..2602640) Methylobacterium extorquens DM4 8192624 YP_003068217.1 CDS METDI2698 NC_012988.1 2602651 2603526 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11406279, 9746353; Product type pe : putative enzyme; putative DNA/RNA non-specific endonuclease complement(2602651..2603526) Methylobacterium extorquens DM4 8192625 YP_003068218.1 CDS METDI2699 NC_012988.1 2603534 2603788 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2603534..2603788) Methylobacterium extorquens DM4 8192626 YP_003068219.1 CDS dxs NC_012988.1 2604112 2606094 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2604112..2606094 Methylobacterium extorquens DM4 8192627 YP_003068220.1 CDS METDI2701 NC_012988.1 2606285 2607328 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dihydroflavonol-4-reductase (Dihydrokaempferol 4-reductase) 2606285..2607328 Methylobacterium extorquens DM4 8195321 YP_003068221.1 CDS METDI2702 NC_012988.1 2607325 2608224 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phytoene synthase 2607325..2608224 Methylobacterium extorquens DM4 8192628 YP_003068222.1 CDS METDI2703 NC_012988.1 2608221 2609072 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phytoene synthase 2608221..2609072 Methylobacterium extorquens DM4 8192629 YP_003068223.1 CDS METDI2704 NC_012988.1 2609072 2610373 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, putative amine oxidase 2609072..2610373 Methylobacterium extorquens DM4 8192630 YP_003068224.1 CDS shc NC_012988.1 2610418 2612421 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9555026; Product type e : enzyme; squalene-hopene-cyclase 2610418..2612421 Methylobacterium extorquens DM4 8192631 YP_003068225.1 CDS METDI2706 NC_012988.1 2612555 2613223 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme; hypothetical protein 2612555..2613223 Methylobacterium extorquens DM4 8196117 YP_003068226.1 CDS rkpG NC_012988.1 2613383 2614756 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9079896; Product type e : enzyme; acyltransferase (wcbT-like, rkpG-like) complement(2613383..2614756) Methylobacterium extorquens DM4 8192632 YP_003068227.1 CDS METDI2708 NC_012988.1 2614753 2622159 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16404952; Product type pe : putative enzyme; putative fatty acid synthase multidomain protein (rkpA-like; wcbR-like) complement(2614753..2622159) Methylobacterium extorquens DM4 8195998 YP_003068228.1 CDS METDI2709 NC_012988.1 2622357 2622686 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2622357..2622686) Methylobacterium extorquens DM4 8192633 YP_003068229.1 CDS ugdH NC_012988.1 2622679 2623983 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9765575; Product type e : enzyme; UDP-glucose-6-dehydrogenase complement(2622679..2623983) Methylobacterium extorquens DM4 8192634 YP_003068230.1 CDS METDI2711 NC_012988.1 2624083 2626236 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase complement(2624083..2626236) Methylobacterium extorquens DM4 8196297 YP_003068231.1 CDS METDI2712 NC_012988.1 2626243 2627289 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2626243..2627289) Methylobacterium extorquens DM4 8192635 YP_003068232.1 CDS oxlT NC_012988.1 2627858 2629075 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11113128, 11274108, 11500368, 11919184, 8636101, 9651403; Product type pt : putative transporter; putative oxalate/formate antiporter complement(2627858..2629075) Methylobacterium extorquens DM4 8196269 YP_003068233.1 CDS eutB NC_012988.1 2629775 2631157 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3905806; Product type e : enzyme; ethanolamine ammonia-lyase, heavy chain 2629775..2631157 Methylobacterium extorquens DM4 8195819 YP_003068234.1 CDS METDI2715 NC_012988.1 2631154 2631936 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2197274; Product type pe : putative enzyme; putative ethanolamine ammonia-lyase light chain (eutC-like) 2631154..2631936 Methylobacterium extorquens DM4 8195337 YP_003068235.1 CDS METDI2716 NC_012988.1 2632382 2634112 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 2632382..2634112 Methylobacterium extorquens DM4 8192637 YP_003068236.1 CDS METDI2717 NC_012988.1 2634132 2634986 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2634132..2634986 Methylobacterium extorquens DM4 8192638 YP_003068237.1 CDS xthA NC_012988.1 2635018 2635812 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3049539; Product type e : enzyme; Exodeoxyribonuclease III (Exonuclease III) (EXO III) (AP endonuclease VI) complement(2635018..2635812) Methylobacterium extorquens DM4 8192639 YP_003068238.1 CDS METDI2719 NC_012988.1 2635974 2636633 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2635974..2636633 Methylobacterium extorquens DM4 8196345 YP_003068239.1 CDS METDI2720 NC_012988.1 2636726 2638657 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411265; Product type pe : putative enzyme; putative Propionate-CoA ligase (Propionyl-CoA synthetase) (prpE-like) complement(2636726..2638657) Methylobacterium extorquens DM4 8192640 YP_003068240.1 CDS METDI2722 NC_012988.1 2638874 2639050 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2638874..2639050) Methylobacterium extorquens DM4 8192641 YP_003068241.1 CDS METDI2723 NC_012988.1 2639302 2639523 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2639302..2639523 Methylobacterium extorquens DM4 8192642 YP_003068242.1 CDS METDI2724 NC_012988.1 2639751 2639927 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2639751..2639927) Methylobacterium extorquens DM4 8192643 YP_003068243.1 CDS purE NC_012988.1 2640229 2640726 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10574791, 8117684; Product type e : enzyme; phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit 2640229..2640726 Methylobacterium extorquens DM4 8192644 YP_003068244.1 CDS purK NC_012988.1 2640744 2641856 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10074353, 10569930, 8117684, 9797284; Product type e : enzyme; phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit 2640744..2641856 Methylobacterium extorquens DM4 8195933 YP_003068245.1 CDS METDI2727 NC_012988.1 2642244 2643104 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2642244..2643104 Methylobacterium extorquens DM4 8195936 YP_003068246.1 CDS METDI2728 NC_012988.1 2643510 2643890 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; response regulator receiver 2643510..2643890 Methylobacterium extorquens DM4 8192645 YP_003068247.1 CDS glpX NC_012988.1 2643961 2644956 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(2643961..2644956) Methylobacterium extorquens DM4 8192646 YP_003068248.1 CDS hom NC_012988.1 2645192 2646514 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(2645192..2646514) Methylobacterium extorquens DM4 8195509 YP_003068249.1 CDS METDI2731 NC_012988.1 2646881 2647180 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2646881..2647180 Methylobacterium extorquens DM4 8195571 YP_003068250.1 CDS METDI2732 NC_012988.1 2647220 2648206 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2647220..2648206) Methylobacterium extorquens DM4 8192647 YP_003068251.1 CDS METDI2733 NC_012988.1 2648311 2648649 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2648311..2648649) Methylobacterium extorquens DM4 8192648 YP_003068252.1 CDS yeiM NC_012988.1 2648725 2649975 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium/proton nucleoside transporter complement(2648725..2649975) Methylobacterium extorquens DM4 8192649 YP_003068253.1 CDS METDI2735 NC_012988.1 2650065 2650727 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2650065..2650727) Methylobacterium extorquens DM4 8196360 YP_003068254.1 CDS METDI2736 NC_012988.1 2651076 2651375 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2651076..2651375 Methylobacterium extorquens DM4 8192650 YP_003068255.1 CDS METDI2737 NC_012988.1 2651429 2652577 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11157937, 9387226; Product type pe : putative enzyme; putative glycosyl transferase complement(2651429..2652577) Methylobacterium extorquens DM4 8192651 YP_003068256.1 CDS METDI2738 NC_012988.1 2652661 2653863 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA topoisomerase I 2652661..2653863 Methylobacterium extorquens DM4 8192652 YP_003068257.1 CDS METDI2739 NC_012988.1 2653883 2654977 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2653883..2654977) Methylobacterium extorquens DM4 8192653 YP_003068258.1 CDS METDI2740 NC_012988.1 2655124 2655306 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2655124..2655306 Methylobacterium extorquens DM4 8192654 YP_003068259.1 CDS METDI2741 NC_012988.1 2655288 2656703 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cytochrome bd-quinol oxidase subunit I 2655288..2656703 Methylobacterium extorquens DM4 8192655 YP_003068260.1 CDS METDI2742 NC_012988.1 2656795 2657502 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Response regulator, CheY-like and LuxR domain complement(2656795..2657502) Methylobacterium extorquens DM4 8192656 YP_003068261.1 CDS METDI2743 NC_012988.1 2657684 2658580 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2657684..2658580) Methylobacterium extorquens DM4 8192657 YP_003068262.1 CDS METDI2744 NC_012988.1 2658688 2659134 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2658688..2659134) Methylobacterium extorquens DM4 8192658 YP_003068263.1 CDS METDI2745 NC_012988.1 2659307 2659555 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2659307..2659555) Methylobacterium extorquens DM4 8192659 YP_003068264.1 CDS ftr1 NC_012988.1 2660009 2660839 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8599111; Product type e : enzyme; Iron permease FTR1 2660009..2660839 Methylobacterium extorquens DM4 8192660 YP_003068265.1 CDS METDI2747 NC_012988.1 2660952 2661425 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotyrosine protein phosphatase complement(2660952..2661425) Methylobacterium extorquens DM4 8195447 YP_003068266.1 CDS METDI2748 NC_012988.1 2661733 2662257 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2661733..2662257) Methylobacterium extorquens DM4 8192661 YP_003068267.1 CDS hisD NC_012988.1 2662387 2663682 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; bifunctional HisD: L-histidinal:NAD+ dehydrogenase ; L-histidinol:NAD+ dehydrogenase complement(2662387..2663682) Methylobacterium extorquens DM4 8192662 YP_003068268.1 CDS METDI2750 NC_012988.1 2663714 2664169 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2663714..2664169) Methylobacterium extorquens DM4 8195560 YP_003068269.1 CDS METDI2751 NC_012988.1 2664463 2664843 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2664463..2664843 Methylobacterium extorquens DM4 8192663 YP_003068270.1 CDS murA NC_012988.1 2664939 2666228 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(2664939..2666228) Methylobacterium extorquens DM4 8192664 YP_003068271.1 CDS METDI2753 NC_012988.1 2666420 2666569 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2666420..2666569) Methylobacterium extorquens DM4 8195736 YP_003068272.1 CDS METDI2754 NC_012988.1 2666819 2666992 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2666819..2666992 Methylobacterium extorquens DM4 8192665 YP_003068273.1 CDS hemA NC_012988.1 2667158 2668546 D catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 2667158..2668546 Methylobacterium extorquens DM4 8192666 YP_003068274.1 CDS METDI2756 NC_012988.1 2668586 2668792 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2668586..2668792 Methylobacterium extorquens DM4 8195547 YP_003068275.1 CDS METDI2757 NC_012988.1 2668789 2669256 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2668789..2669256 Methylobacterium extorquens DM4 8192667 YP_003068276.1 CDS METDI2758 NC_012988.1 2669263 2669817 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2669263..2669817) Methylobacterium extorquens DM4 8192668 YP_003068277.1 CDS yjdM NC_012988.1 2670039 2670344 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Alkylphosphonate uptake protein 2670039..2670344 Methylobacterium extorquens DM4 8192669 YP_003068278.1 CDS METDI2760 NC_012988.1 2670367 2671098 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Beta-lactamase-like complement(2670367..2671098) Methylobacterium extorquens DM4 8196370 YP_003068279.1 CDS METDI2761 NC_012988.1 2671483 2672649 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2671483..2672649 Methylobacterium extorquens DM4 8192670 YP_003068280.1 CDS aroG2 NC_012988.1 2672787 2674169 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8760910; Product type e : enzyme; 2-dehydro-3-deoxyphosphoheptonate aldolase 2672787..2674169 Methylobacterium extorquens DM4 8192671 YP_003068281.1 CDS METDI2763 NC_012988.1 2674390 2674605 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2674390..2674605 Methylobacterium extorquens DM4 8195094 YP_003068282.1 CDS METDI2764 NC_012988.1 2674683 2675228 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2674683..2675228) Methylobacterium extorquens DM4 8192672 YP_003068283.1 CDS METDI2765 NC_012988.1 2675560 2676474 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2675560..2676474 Methylobacterium extorquens DM4 8192673 YP_003068284.1 CDS gmk NC_012988.1 2676509 2677180 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2676509..2677180 Methylobacterium extorquens DM4 8192674 YP_003068285.1 CDS METDI2767 NC_012988.1 2677227 2678975 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused ATPase and transmembrane permease domains complement(2677227..2678975) Methylobacterium extorquens DM4 8195523 YP_003068286.1 CDS METDI2768 NC_012988.1 2679148 2679663 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2679148..2679663) Methylobacterium extorquens DM4 8192675 YP_003068287.1 CDS METDI2769 NC_012988.1 2679852 2680517 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cob(II)yrinic acid a,c-diamide reductase complement(2679852..2680517) Methylobacterium extorquens DM4 8192676 YP_003068288.1 CDS METDI2770 NC_012988.1 2680774 2680881 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2680774..2680881) Methylobacterium extorquens DM4 8192677 YP_003068289.1 CDS METDI2771 NC_012988.1 2681031 2681426 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2681031..2681426 Methylobacterium extorquens DM4 8192678 YP_003068290.1 CDS METDI2772 NC_012988.1 2681464 2683644 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative Catecholate siderophore receptor fiu precursor (TonB-dependent receptor fiu) complement(2681464..2683644) Methylobacterium extorquens DM4 8192679 YP_003068291.1 CDS eda NC_012988.1 2684144 2684764 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 4560498, 7016177; Product type e : enzyme; multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase; 2-keto-4-hydroxyglutarate aldolase; oxaloacetate decarboxylase complement(2684144..2684764) Methylobacterium extorquens DM4 8192680 YP_003068292.1 CDS edd NC_012988.1 2684984 2686813 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2684984..2686813) Methylobacterium extorquens DM4 8195325 YP_003068293.1 CDS hslO NC_012988.1 2687163 2688170 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin complement(2687163..2688170) Methylobacterium extorquens DM4 8195326 YP_003068294.1 CDS METDI2776 NC_012988.1 2688430 2690541 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative outer membrane porin (OMPA-like) complement(2688430..2690541) Methylobacterium extorquens DM4 8192681 YP_003068295.1 CDS METDI2777 NC_012988.1 2690898 2691410 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2690898..2691410) Methylobacterium extorquens DM4 8192682 YP_003068296.1 CDS ndk NC_012988.1 2691788 2692210 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2691788..2692210 Methylobacterium extorquens DM4 8192683 YP_003068297.1 CDS METDI2779 NC_012988.1 2692495 2692875 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2692495..2692875 Methylobacterium extorquens DM4 8195774 YP_003068298.1 CDS METDI2780 NC_012988.1 2692972 2694108 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallopeptidase complement(2692972..2694108) Methylobacterium extorquens DM4 8192684 YP_003068299.1 CDS METDI2781 NC_012988.1 2694116 2695405 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2694116..2695405) Methylobacterium extorquens DM4 8192685 YP_003068300.1 CDS METDI2782 NC_012988.1 2695794 2696006 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2695794..2696006) Methylobacterium extorquens DM4 8192686 YP_003068301.1 CDS cstA NC_012988.1 2696035 2698092 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1848300; Product type m : membrane component; carbon starvation protein A precursor complement(2696035..2698092) Methylobacterium extorquens DM4 8192687 YP_003068302.1 CDS METDI2784 NC_012988.1 2698393 2699076 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2698393..2699076) Methylobacterium extorquens DM4 8195226 YP_003068303.1 CDS METDI2785 NC_012988.1 2699009 2699794 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2699009..2699794) Methylobacterium extorquens DM4 8192688 YP_003068304.1 CDS METDI2786 NC_012988.1 2699814 2700449 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2699814..2700449) Methylobacterium extorquens DM4 8192689 YP_003068305.1 CDS METDI2788 NC_012988.1 2700695 2701009 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2700695..2701009 Methylobacterium extorquens DM4 8192690 YP_003068306.1 CDS METDI2789 NC_012988.1 2701109 2703250 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Histidine protein kinase of the HWE family 2701109..2703250 Methylobacterium extorquens DM4 8192691 YP_003068307.1 CDS dkgA NC_012988.1 2703273 2704109 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10427017, 11934293, 99357626; Product type e : enzyme; 2,5-diketo-D-gluconate reductase A complement(2703273..2704109) Methylobacterium extorquens DM4 8192692 YP_003068308.1 CDS METDI2791 NC_012988.1 2704224 2705003 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1522059, 1551834; Product type pr : putative regulator; putative Regulatory protein, Crp family complement(2704224..2705003) Methylobacterium extorquens DM4 8195297 YP_003068309.1 CDS glgA NC_012988.1 2705304 2706836 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(2705304..2706836) Methylobacterium extorquens DM4 8192693 YP_003068310.1 CDS METDI2793 NC_012988.1 2707096 2708721 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl hydrolase complement(2707096..2708721) Methylobacterium extorquens DM4 8195488 YP_003068311.1 CDS glgP NC_012988.1 2709050 2711584 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glycogen phosphorylase 2709050..2711584 Methylobacterium extorquens DM4 8192694 YP_003068312.1 CDS METDI2795 NC_012988.1 2711762 2712703 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2711762..2712703) Methylobacterium extorquens DM4 8195490 YP_003068313.1 CDS METDI2796 NC_012988.1 2712747 2713175 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2712747..2713175) Methylobacterium extorquens DM4 8192695 YP_003068314.1 CDS METDI2797 NC_012988.1 2713296 2716226 R Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; diguanylate cyclase (GGDEF domain) /phosphodiesterase (EAL domain) with PAS/PAC and GAF sensor domains complement(2713296..2716226) Methylobacterium extorquens DM4 8192696 YP_003068315.1 CDS METDI2798 NC_012988.1 2716656 2717675 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11024259, 7537247, 8051012; Product type pe : putative enzyme; putative glycosyl transferase 2716656..2717675 Methylobacterium extorquens DM4 8192697 YP_003068316.1 CDS METDI2799 NC_012988.1 2717687 2718610 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative UDP-glucose 4-epimerase 2717687..2718610 Methylobacterium extorquens DM4 8192698 YP_003068317.1 CDS azoR NC_012988.1 2718615 2719226 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11583992, 16511052; Product type e : enzyme; FMN-dependent NADH-azoreductase (FMN-dependent NADH-azo compound oxidoreductase) (Azo-dye reductase) complement(2718615..2719226) Methylobacterium extorquens DM4 8192699 YP_003068318.1 CDS METDI2801 NC_012988.1 2719303 2719707 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11443074, 9573147; Product type pr : putative regulator; putative transcriptional regulator, HxlR family 2719303..2719707 Methylobacterium extorquens DM4 8195123 YP_003068319.1 CDS METDI2802 NC_012988.1 2719727 2721700 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleotide sugar epimerase/dehydratase complement(2719727..2721700) Methylobacterium extorquens DM4 8192700 YP_003068320.1 CDS METDI2803 NC_012988.1 2721804 2722655 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2721804..2722655) Methylobacterium extorquens DM4 8192701 YP_003068321.1 CDS METDI2804 NC_012988.1 2722662 2723003 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2722662..2723003) Methylobacterium extorquens DM4 8192702 YP_003068322.1 CDS METDI2805 NC_012988.1 2723029 2723595 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2723029..2723595) Methylobacterium extorquens DM4 8192703 YP_003068323.1 CDS METDI2806 NC_012988.1 2723667 2724227 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2723667..2724227) Methylobacterium extorquens DM4 8192704 YP_003068324.1 CDS hss NC_012988.1 2724315 2725763 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8841401; Product type e : enzyme; homospermidine synthase complement(2724315..2725763) Methylobacterium extorquens DM4 8192705 YP_003068325.1 CDS METDI2808 NC_012988.1 2726037 2726225 D Evidence 6 : Doubtful CDS; hypothetical protein 2726037..2726225 Methylobacterium extorquens DM4 8195580 YP_003068326.1 CDS METDI2809 NC_012988.1 2726385 2726942 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase with acyl-CoA N-acyltransferase domain complement(2726385..2726942) Methylobacterium extorquens DM4 8192706 YP_003068327.1 CDS METDI2810 NC_012988.1 2727121 2728287 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11073919; Product type pe : putative enzyme; putative ornithine/diaminopimelate PLP-dependent decarboxylase complement(2727121..2728287) Methylobacterium extorquens DM4 8192707 YP_003068328.1 CDS mdoG NC_012988.1 2728972 2730591 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 2728972..2730591 Methylobacterium extorquens DM4 8192708 YP_003068329.1 CDS METDI2812 NC_012988.1 2730564 2731100 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2730564..2731100 Methylobacterium extorquens DM4 8195676 YP_003068330.1 CDS METDI2813 NC_012988.1 2731244 2732332 D Evidence 2b : Function of strongly homologous gene; PubMedId : 97165929; Product type e : enzyme; NADH:flavin oxidoreductase/NADH oxidase; putative FMN-linked N-ethylmaleimide reductase 2731244..2732332 Methylobacterium extorquens DM4 8192709 YP_003068331.1 CDS METDI2814 NC_012988.1 2732414 2733127 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase family hydrolase 2732414..2733127 Methylobacterium extorquens DM4 8192710 YP_003068332.1 CDS METDI2815 NC_012988.1 2733121 2733618 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2733121..2733618) Methylobacterium extorquens DM4 8192711 YP_003068333.1 CDS METDI2816 NC_012988.1 2733776 2734342 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2733776..2734342 Methylobacterium extorquens DM4 8192712 YP_003068334.1 CDS METDI2817 NC_012988.1 2734339 2734857 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2734339..2734857 Methylobacterium extorquens DM4 8192713 YP_003068335.1 CDS plsX NC_012988.1 2735022 2736080 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Fatty acid/phospholipid synthesis protein 2735022..2736080 Methylobacterium extorquens DM4 8192714 YP_003068336.1 CDS fabH NC_012988.1 2736114 2737094 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10593943, 11078736, 11243824, 8631920; Product type e : enzyme; 3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase 2736114..2737094 Methylobacterium extorquens DM4 8195867 YP_003068337.1 CDS ihfA NC_012988.1 2737303 2737629 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2991205, 3528129, 6397321, 8980235, 91348524, 92021785, 92155171; Product type f : factor; integration host factor (IHF), DNA-binding protein, alpha subunit 2737303..2737629 Methylobacterium extorquens DM4 8195346 YP_003068338.1 CDS METDI2821 NC_012988.1 2737683 2738180 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, MerR family 2737683..2738180 Methylobacterium extorquens DM4 8195589 YP_003068339.1 CDS METDI2823 NC_012988.1 2738344 2738742 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2738344..2738742 Methylobacterium extorquens DM4 8192715 YP_003068340.1 CDS METDI2824 NC_012988.1 2738884 2739357 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2738884..2739357 Methylobacterium extorquens DM4 8192716 YP_003068341.1 CDS METDI2825 NC_012988.1 2739617 2741569 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2739617..2741569 Methylobacterium extorquens DM4 8192717 YP_003068342.1 CDS METDI2826 NC_012988.1 2741673 2742977 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2741673..2742977 Methylobacterium extorquens DM4 8192718 YP_003068343.1 CDS METDI2827 NC_012988.1 2743025 2744596 D Evidence 4 : Homologs of previously reported genes of unknown function; SpoVR family protein 2743025..2744596 Methylobacterium extorquens DM4 8192719 YP_003068344.1 CDS purN NC_012988.1 2744774 2745433 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10606510, 3301838; Product type e : enzyme; phosphoribosylglycinamide formyltransferase 1 complement(2744774..2745433) Methylobacterium extorquens DM4 8192720 YP_003068345.1 CDS purM NC_012988.1 2745430 2746497 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(2745430..2746497) Methylobacterium extorquens DM4 8195939 YP_003068346.1 CDS METDI2830 NC_012988.1 2746494 2746655 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2746494..2746655) Methylobacterium extorquens DM4 8195938 YP_003068347.1 CDS METDI2831 NC_012988.1 2746801 2747913 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease (PerM family) 2746801..2747913 Methylobacterium extorquens DM4 8192721 YP_003068348.1 CDS METDI2832 NC_012988.1 2748035 2748793 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2748035..2748793 Methylobacterium extorquens DM4 8192722 YP_003068349.1 CDS ppk NC_012988.1 2748933 2751299 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2748933..2751299 Methylobacterium extorquens DM4 8192723 YP_003068350.1 CDS METDI2834 NC_012988.1 2751488 2753041 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; exopolyphosphatase 2751488..2753041 Methylobacterium extorquens DM4 8195884 YP_003068351.1 CDS METDI2835 NC_012988.1 2753120 2753419 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2753120..2753419) Methylobacterium extorquens DM4 8192724 YP_003068352.1 CDS aatA NC_012988.1 2753949 2755151 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8096210; Product type e : enzyme; aspartate aminotransferase A complement(2753949..2755151) Methylobacterium extorquens DM4 8192725 YP_003068353.1 CDS METDI2837 NC_012988.1 2755592 2757574 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Acyl CoA:acetate/3-ketoacid CoA transferase; fused alpha subunit and beta subunit 2755592..2757574 Methylobacterium extorquens DM4 8195043 YP_003068354.1 CDS METDI2838 NC_012988.1 2757951 2759621 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative methyl-accepting chemotaxis sensory transducer precursor 2757951..2759621 Methylobacterium extorquens DM4 8192726 YP_003068355.1 CDS rpsB NC_012988.1 2759877 2760926 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2759877..2760926 Methylobacterium extorquens DM4 8192727 YP_003068356.1 CDS tsf NC_012988.1 2761071 2761991 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2761071..2761991 Methylobacterium extorquens DM4 8196053 YP_003068357.1 CDS pyrH NC_012988.1 2762158 2762880 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15857829; Product type e : enzyme; uridylate kinase 2762158..2762880 Methylobacterium extorquens DM4 8196286 YP_003068358.1 CDS ppa NC_012988.1 2762992 2763531 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(2762992..2763531) Methylobacterium extorquens DM4 8195953 YP_003068359.1 CDS METDI2843 NC_012988.1 2763806 2764312 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative GCN5-related N-acetyltransferase complement(2763806..2764312) Methylobacterium extorquens DM4 8195880 YP_003068360.1 CDS METDI2844 NC_012988.1 2764450 2765175 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2764450..2765175 Methylobacterium extorquens DM4 8192728 YP_003068361.1 CDS METDI2845 NC_012988.1 2765184 2766179 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2765184..2766179 Methylobacterium extorquens DM4 8192729 YP_003068362.1 CDS lpxD NC_012988.1 2766241 2767296 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(2766241..2767296) Methylobacterium extorquens DM4 8192730 YP_003068363.1 CDS METDI2847 NC_012988.1 2767459 2770023 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative outer membrane protein assembly factor complement(2767459..2770023) Methylobacterium extorquens DM4 8195649 YP_003068364.1 CDS METDI2848 NC_012988.1 2770384 2771544 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15686556; Product type e : enzyme; membrane-associated zinc metalloprotease complement(2770384..2771544) Methylobacterium extorquens DM4 8192731 YP_003068365.1 CDS dxr NC_012988.1 2771761 2772939 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(2771761..2772939) Methylobacterium extorquens DM4 8192732 YP_003068366.1 CDS cdsA NC_012988.1 2772954 2773814 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2995359, 30751; Product type e : enzyme; CDP-diglyceride synthase complement(2772954..2773814) Methylobacterium extorquens DM4 8195320 YP_003068367.1 CDS uppS NC_012988.1 2773814 2774593 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11287651, 9882662; Product type e : enzyme; undecaprenyl pyrophosphate synthetase (di-trans, poly-cis-decaprenylcistransferase) complement(2773814..2774593) Methylobacterium extorquens DM4 8195160 YP_003068368.1 CDS frr NC_012988.1 2774664 2775227 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(2774664..2775227) Methylobacterium extorquens DM4 8196306 YP_003068369.1 CDS METDI2853 NC_012988.1 2775560 2776699 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2775560..2776699 Methylobacterium extorquens DM4 8195444 YP_003068370.1 CDS METDI2854 NC_012988.1 2777022 2778302 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ubiquinone biosynthesis hydroxylase/monooxygenase complement(2777022..2778302) Methylobacterium extorquens DM4 8192733 YP_003068371.1 CDS METDI2855 NC_012988.1 2778435 2778608 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2778435..2778608 Methylobacterium extorquens DM4 8192734 YP_003068372.1 CDS METDI2856 NC_012988.1 2778695 2779639 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1200544, 12878731, 13129938, 8113168, 9689094; Product type r : regulator; transcriptional regulator, LysR family 2778695..2779639 Methylobacterium extorquens DM4 8192735 YP_003068373.1 CDS METDI2857 NC_012988.1 2779884 2780633 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 3-oxoacyl-[acyl-carrier-protein] reductase (fabG-like) 2779884..2780633 Methylobacterium extorquens DM4 8192736 YP_003068374.1 CDS METDI2858 NC_012988.1 2780651 2781511 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transketolase, alpha subunit 2780651..2781511 Methylobacterium extorquens DM4 8192737 YP_003068375.1 CDS METDI2859 NC_012988.1 2781508 2782527 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transketolase (C-terminal domain) 2781508..2782527 Methylobacterium extorquens DM4 8192738 YP_003068376.1 CDS METDI2860 NC_012988.1 2782690 2783706 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1809844; Product type prc : putative receptor; putative ABC transporter substrate-binding protein, putative C4-dicarboxylate-binding periplasmic protein DctP precursor 2782690..2783706 Methylobacterium extorquens DM4 8192739 YP_003068377.1 CDS METDI2861 NC_012988.1 2783718 2785604 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease protein 2783718..2785604 Methylobacterium extorquens DM4 8192740 YP_003068378.1 CDS METDI2862 NC_012988.1 2785686 2785862 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2785686..2785862) Methylobacterium extorquens DM4 8192741 YP_003068379.1 CDS METDI2863 NC_012988.1 2785994 2786248 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2785994..2786248) Methylobacterium extorquens DM4 8192742 YP_003068380.1 CDS METDI2864 NC_012988.1 2786474 2787199 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10433972; Product type pe : putative enzyme; putative CoxB-related 2786474..2787199 Methylobacterium extorquens DM4 8192743 YP_003068381.1 CDS METDI2865 NC_012988.1 2787429 2795819 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16113259; hypothetical protein complement(2787429..2795819) Methylobacterium extorquens DM4 8192744 YP_003068382.1 CDS tesB NC_012988.1 2796215 2797078 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10876240; Product type e : enzyme; acyl-CoA thioesterase II 2796215..2797078 Methylobacterium extorquens DM4 8192745 YP_003068383.1 CDS glnK NC_012988.1 2797341 2797679 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11847102, 7590157, 7904973, 8843440, 9720863, 9733647, 99248410; Product type r : regulator; nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB 2797341..2797679 Methylobacterium extorquens DM4 8196183 YP_003068384.1 CDS amtB NC_012988.1 2797812 2799308 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ammonium transport protein (Amt family) 2797812..2799308 Methylobacterium extorquens DM4 8195504 YP_003068385.1 CDS METDI2869 NC_012988.1 2799650 2800912 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2799650..2800912 Methylobacterium extorquens DM4 8195075 YP_003068386.1 CDS ftsK NC_012988.1 2801094 2803709 D Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; DNA-binding membrane protein required for chromosome resolution and partitioning 2801094..2803709 Methylobacterium extorquens DM4 8192746 YP_003068387.1 CDS METDI2871 NC_012988.1 2803861 2806020 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent receptor/siderophore receptor protein 2803861..2806020 Methylobacterium extorquens DM4 8195453 YP_003068388.1 CDS METDI2872 NC_012988.1 2806376 2808343 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase of the HWE family 2806376..2808343 Methylobacterium extorquens DM4 8192747 YP_003068389.1 CDS fdh4B NC_012988.1 2808366 2808668 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 17921299; Product type e : enzyme; Formate dehydrogenase subunit B complement(2808366..2808668) Methylobacterium extorquens DM4 8192748 YP_003068390.1 CDS fdh4A NC_012988.1 2808665 2810980 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 17921299; Product type e : enzyme; Formate dehydrogenase subunit A complement(2808665..2810980) Methylobacterium extorquens DM4 8195370 YP_003068391.1 CDS pyrD NC_012988.1 2811502 2812578 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(2811502..2812578) Methylobacterium extorquens DM4 8195369 YP_003068392.1 CDS METDI2876 NC_012988.1 2812575 2812925 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2812575..2812925) Methylobacterium extorquens DM4 8195949 YP_003068393.1 CDS METDI2877 NC_012988.1 2813148 2813780 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LexA/Signal peptidase 2813148..2813780 Methylobacterium extorquens DM4 8192749 YP_003068394.1 CDS METDI2878 NC_012988.1 2813791 2814120 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(2813791..2814120) Methylobacterium extorquens DM4 8192750 YP_003068395.1 CDS METDI2879 NC_012988.1 2814291 2814599 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2814291..2814599) Methylobacterium extorquens DM4 8192751 YP_003068396.1 CDS cysE-1 NC_012988.1 2814642 2815502 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10617639, 3309158, 9622597; Product type e : enzyme; serine acetyltransferase complement(2814642..2815502) Methylobacterium extorquens DM4 8192752 YP_003068397.1 CDS METDI2881 NC_012988.1 2815783 2816682 R consists of N-terminal helix-turn-helix domain and C-terminal shikimate kinase-like domain which may bind benzoyl-CoA; controls inducible expression of the bzd catabolic operon that is involved in the anaerobic catabolism of benzoate; anaerobic benzoate catabolism transcriptional regulator complement(2815783..2816682) Methylobacterium extorquens DM4 8195251 YP_003068398.1 CDS METDI2882 NC_012988.1 2817145 2817297 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2817145..2817297) Methylobacterium extorquens DM4 8192753 YP_003068399.1 CDS METDI2883 NC_012988.1 2817346 2819619 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; integral membrane sensor signal transduction histidine kinase complement(2817346..2819619) Methylobacterium extorquens DM4 8192754 YP_003068400.1 CDS METDI2884 NC_012988.1 2819741 2819944 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2819741..2819944) Methylobacterium extorquens DM4 8192755 YP_003068401.1 CDS METDI2885 NC_012988.1 2819956 2820222 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2819956..2820222) Methylobacterium extorquens DM4 8192756 YP_003068402.1 CDS ompR NC_012988.1 2820396 2821130 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; response regulator in two-component regulatory system (OmpR family) complement(2820396..2821130) Methylobacterium extorquens DM4 8192757 YP_003068403.1 CDS METDI2887 NC_012988.1 2821476 2823326 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative two-component system regulator: response regulator receiver (N-terminal) and histidine kinase (C-terminal) 2821476..2823326 Methylobacterium extorquens DM4 8195806 YP_003068404.1 CDS METDI2888 NC_012988.1 2823412 2823810 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glyoxalase/Bleomycin resistance protein/dioxygenase complement(2823412..2823810) Methylobacterium extorquens DM4 8192758 YP_003068405.1 CDS METDI2889 NC_012988.1 2823949 2824221 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2823949..2824221) Methylobacterium extorquens DM4 8192759 YP_003068406.1 CDS METDI2890 NC_012988.1 2824319 2825011 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator with N-terminal cNMP-binding domain complement(2824319..2825011) Methylobacterium extorquens DM4 8192760 YP_003068407.1 CDS METDI2891 NC_012988.1 2825234 2826415 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2825234..2826415) Methylobacterium extorquens DM4 8192761 YP_003068408.1 CDS METDI2894 NC_012988.1 2828993 2829493 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2828993..2829493 Methylobacterium extorquens DM4 8192764 YP_003068409.1 CDS METDI2895 NC_012988.1 2829737 2830342 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Oxidoreductase, molybdopterin binding 2829737..2830342 Methylobacterium extorquens DM4 8192765 YP_003068410.1 CDS METDI2896 NC_012988.1 2830347 2831087 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, FAD-binding domain 2830347..2831087 Methylobacterium extorquens DM4 8192766 YP_003068411.1 CDS METDI2897 NC_012988.1 2831256 2831597 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2831256..2831597) Methylobacterium extorquens DM4 8192767 YP_003068412.1 CDS METDI2899 NC_012988.1 2831814 2832080 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2831814..2832080) Methylobacterium extorquens DM4 8192768 YP_003068413.1 CDS aroA NC_012988.1 2832512 2833822 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 2832512..2833822 Methylobacterium extorquens DM4 8192769 YP_003068414.1 CDS cmk NC_012988.1 2833819 2834487 D Evidence 2b : Function of strongly homologous gene; PubMedId : 6281725, 95138007; Product type e : enzyme; cytidine monophosphate (CMP) kinase 2833819..2834487 Methylobacterium extorquens DM4 8195092 YP_003068415.1 CDS METDI2902 NC_012988.1 2834499 2834816 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2834499..2834816) Methylobacterium extorquens DM4 8195176 YP_003068416.1 CDS METDI2903 NC_012988.1 2835554 2836912 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2835554..2836912 Methylobacterium extorquens DM4 8196264 YP_003068417.1 CDS METDI2904 NC_012988.1 2836949 2838211 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14523113, 1761231, 9651492, 9791104; Product type pe : putative enzyme; putative glycosyl transferase 2836949..2838211 Methylobacterium extorquens DM4 8192771 YP_003068418.1 CDS METDI2905 NC_012988.1 2838218 2838994 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; creatininase (creatine amidohydrolase) complement(2838218..2838994) Methylobacterium extorquens DM4 8192772 YP_003068419.1 CDS METDI2906 NC_012988.1 2839176 2840084 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2839176..2840084 Methylobacterium extorquens DM4 8192773 YP_003068420.1 CDS METDI2907 NC_012988.1 2840068 2840484 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2840068..2840484) Methylobacterium extorquens DM4 8192774 YP_003068421.1 CDS METDI2908 NC_012988.1 2840615 2840818 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10376822, 11988534; hypothetical protein complement(2840615..2840818) Methylobacterium extorquens DM4 8192775 YP_003068422.1 CDS oxlT NC_012988.1 2841123 2842433 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type pt : putative transporter; putative oxalate/formate antiporter 2841123..2842433 Methylobacterium extorquens DM4 8192776 YP_003068423.1 CDS METDI2910 NC_012988.1 2842430 2843209 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; Fumarylacetoacetate (FAA) hydrolase family 2842430..2843209 Methylobacterium extorquens DM4 8195820 YP_003068424.1 CDS panE NC_012988.1 2843315 2844322 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2-dehydropantoate 2-reductase (ketopantoate reductase) 2843315..2844322 Methylobacterium extorquens DM4 8192777 YP_003068425.1 CDS METDI2912 NC_012988.1 2844319 2845905 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; putative acyl-coenzyme A synthetase 2844319..2845905 Methylobacterium extorquens DM4 8195825 YP_003068426.1 CDS METDI2913 NC_012988.1 2846469 2846750 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2846469..2846750) Methylobacterium extorquens DM4 8192778 YP_003068427.1 CDS METDI2914 NC_012988.1 2846751 2847005 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2846751..2847005) Methylobacterium extorquens DM4 8192779 YP_003068428.1 CDS METDI2915 NC_012988.1 2847121 2847486 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2847121..2847486) Methylobacterium extorquens DM4 8192780 YP_003068429.1 CDS METDI2916 NC_012988.1 2847617 2848819 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2847617..2848819) Methylobacterium extorquens DM4 8192781 YP_003068430.1 CDS phnR NC_012988.1 2848937 2849839 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional activator, LysR family 2848937..2849839 Methylobacterium extorquens DM4 8192782 YP_003068431.1 CDS METDI2918 NC_012988.1 2849823 2850212 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 4-oxalocrotonate tautomerase complement(2849823..2850212) Methylobacterium extorquens DM4 8195861 YP_003068432.1 CDS METDI2919 NC_012988.1 2850473 2851363 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family 2850473..2851363 Methylobacterium extorquens DM4 8192783 YP_003068433.1 CDS METDI2920 NC_012988.1 2851433 2851822 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2851433..2851822) Methylobacterium extorquens DM4 8192784 YP_003068434.1 CDS METDI2921 NC_012988.1 2852048 2852737 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase family hydrolase complement(2852048..2852737) Methylobacterium extorquens DM4 8192785 YP_003068435.1 CDS METDI2922 NC_012988.1 2852875 2854287 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2852875..2854287 Methylobacterium extorquens DM4 8192786 YP_003068436.1 CDS METDI2923 NC_012988.1 2854300 2854935 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2854300..2854935 Methylobacterium extorquens DM4 8192787 YP_003068437.1 CDS METDI2924 NC_012988.1 2854890 2855852 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family complement(2854890..2855852) Methylobacterium extorquens DM4 8192788 YP_003068438.1 CDS METDI2925 NC_012988.1 2855988 2856917 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dioxygenase/glyoxalase family protein 2855988..2856917 Methylobacterium extorquens DM4 8192789 YP_003068439.1 CDS METDI2926 NC_012988.1 2856994 2857623 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2856994..2857623 Methylobacterium extorquens DM4 8192790 YP_003068440.1 CDS METDI2927 NC_012988.1 2857705 2857941 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2857705..2857941) Methylobacterium extorquens DM4 8192791 YP_003068441.1 CDS METDI2928 NC_012988.1 2858219 2858446 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2858219..2858446 Methylobacterium extorquens DM4 8192792 YP_003068442.1 CDS METDI2929 NC_012988.1 2858995 2862474 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2858995..2862474 Methylobacterium extorquens DM4 8192793 YP_003068443.1 CDS rpsL NC_012988.1 2862863 2863234 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 2862863..2863234 Methylobacterium extorquens DM4 8192794 YP_003068444.1 CDS rpsG NC_012988.1 2863341 2863811 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 2863341..2863811 Methylobacterium extorquens DM4 8196063 YP_003068445.1 CDS fusA NC_012988.1 2863875 2865950 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2863875..2865950 Methylobacterium extorquens DM4 8196058 YP_003068446.1 CDS tufB NC_012988.1 2866004 2867194 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 2866004..2867194 Methylobacterium extorquens DM4 8195461 YP_003068447.1 CDS rpsJ NC_012988.1 2867274 2867582 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2867274..2867582 Methylobacterium extorquens DM4 8196290 YP_003068448.1 CDS rplC NC_012988.1 2867633 2868373 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2867633..2868373 Methylobacterium extorquens DM4 8196061 YP_003068449.1 CDS rplD NC_012988.1 2868373 2868993 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2868373..2868993 Methylobacterium extorquens DM4 8196014 YP_003068450.1 CDS rplW NC_012988.1 2868990 2869286 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2868990..2869286 Methylobacterium extorquens DM4 8196015 YP_003068451.1 CDS rplB NC_012988.1 2869312 2870148 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2869312..2870148 Methylobacterium extorquens DM4 8196032 YP_003068452.1 CDS rpsS NC_012988.1 2870154 2870432 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2870154..2870432 Methylobacterium extorquens DM4 8196013 YP_003068453.1 CDS rplV NC_012988.1 2870434 2870817 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2870434..2870817 Methylobacterium extorquens DM4 8196070 YP_003068454.1 CDS rpsC NC_012988.1 2870829 2871575 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10094780, 12244297, 12809609, 387449, 389248, 89263724, 92345329, 93011980; Product type s : structure; 30S ribosomal subunit protein S3 2870829..2871575 Methylobacterium extorquens DM4 8196031 YP_003068455.1 CDS rplP NC_012988.1 2871609 2872022 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2871609..2872022 Methylobacterium extorquens DM4 8196054 YP_003068456.1 CDS rpmC NC_012988.1 2872035 2872250 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10094780, 1092361, 12809609, 3892488, 89287320, 91088242; Product type s : structure; 50S ribosomal subunit protein L29 2872035..2872250 Methylobacterium extorquens DM4 8196025 YP_003068457.1 CDS rpsQ NC_012988.1 2872262 2872528 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2872262..2872528 Methylobacterium extorquens DM4 8196037 YP_003068458.1 CDS METDI2945 NC_012988.1 2872901 2874289 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2872901..2874289 Methylobacterium extorquens DM4 8196068 YP_003068459.1 CDS METDI2946 NC_012988.1 2874503 2874961 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2874503..2874961) Methylobacterium extorquens DM4 8192795 YP_003068460.1 CDS METDI2947 NC_012988.1 2875207 2875671 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, MarR family complement(2875207..2875671) Methylobacterium extorquens DM4 8192796 YP_003068461.1 CDS rplQ NC_012988.1 2875961 2876377 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(2875961..2876377) Methylobacterium extorquens DM4 8192797 YP_003068462.1 CDS rpoA NC_012988.1 2876608 2877627 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(2876608..2877627) Methylobacterium extorquens DM4 8196026 YP_003068463.1 CDS METDI2950 NC_012988.1 2877726 2878607 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallo-beta-lactamase family protein complement(2877726..2878607) Methylobacterium extorquens DM4 8196044 YP_003068464.1 CDS rpsK NC_012988.1 2878645 2879034 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(2878645..2879034) Methylobacterium extorquens DM4 8192798 YP_003068465.1 CDS rpsM NC_012988.1 2879205 2879573 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(2879205..2879573) Methylobacterium extorquens DM4 8196062 YP_003068466.1 CDS adk NC_012988.1 2879877 2880479 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(2879877..2880479) Methylobacterium extorquens DM4 8196064 YP_003068467.1 CDS secY NC_012988.1 2880650 2881993 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10348856, 1633829, 200755, 92156163, 92202287, 92339472, 9564033, 99298179; Product type t : transporter; preprotein translocase, membrane component, transport across inner membrane (General Secretory Pathway) complement(2880650..2881993) Methylobacterium extorquens DM4 8195064 YP_003068468.1 CDS rplO NC_012988.1 2882108 2882617 R late assembly protein; 50S ribosomal protein L15 complement(2882108..2882617) Methylobacterium extorquens DM4 8196108 YP_003068469.1 CDS rpmD NC_012988.1 2882631 2882825 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(2882631..2882825) Methylobacterium extorquens DM4 8196024 YP_003068470.1 CDS rpsE NC_012988.1 2882837 2883415 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(2882837..2883415) Methylobacterium extorquens DM4 8196038 YP_003068471.1 CDS rplR NC_012988.1 2883506 2883868 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(2883506..2883868) Methylobacterium extorquens DM4 8196056 YP_003068472.1 CDS rplF NC_012988.1 2883880 2884413 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(2883880..2884413) Methylobacterium extorquens DM4 8196027 YP_003068473.1 CDS rpsH NC_012988.1 2884430 2884825 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10094780, 12244297, 12809609, 1735715, 36569, 89098950, 90096156, 93257440; Product type s : structure; 30S ribosomal subunit protein S8, and regulator complement(2884430..2884825) Methylobacterium extorquens DM4 8196017 YP_003068474.1 CDS rpsN NC_012988.1 2884838 2885143 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(2884838..2885143) Methylobacterium extorquens DM4 8196059 YP_003068475.1 CDS rplE NC_012988.1 2885185 2885751 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 89313662; Product type s : structure; 50S ribosomal subunit protein L5 complement(2885185..2885751) Methylobacterium extorquens DM4 8196065 YP_003068476.1 CDS rplX NC_012988.1 2885744 2886058 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(2885744..2886058) Methylobacterium extorquens DM4 8196016 YP_003068477.1 CDS rplN NC_012988.1 2886058 2886426 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(2886058..2886426) Methylobacterium extorquens DM4 8196033 YP_003068478.1 CDS METDI2966 NC_012988.1 2886780 2887061 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2886780..2887061) Methylobacterium extorquens DM4 8196023 YP_003068479.1 CDS METDI2967 NC_012988.1 2887370 2887903 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2887370..2887903) Methylobacterium extorquens DM4 8192799 YP_003068480.1 CDS METDI2968 NC_012988.1 2888506 2888886 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2888506..2888886 Methylobacterium extorquens DM4 8192800 YP_003068481.1 CDS METDI2969 NC_012988.1 2889000 2890247 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF domain) 2889000..2890247 Methylobacterium extorquens DM4 8192801 YP_003068482.1 CDS METDI2970 NC_012988.1 2890338 2891408 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2890338..2891408 Methylobacterium extorquens DM4 8192802 YP_003068483.1 CDS METDI2971 NC_012988.1 2891473 2891913 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2891473..2891913) Methylobacterium extorquens DM4 8192803 YP_003068484.1 CDS METDI2972 NC_012988.1 2892112 2892324 D Evidence 6 : Doubtful CDS; hypothetical protein 2892112..2892324 Methylobacterium extorquens DM4 8192804 YP_003068485.1 CDS METDI2973 NC_012988.1 2892321 2892617 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2892321..2892617) Methylobacterium extorquens DM4 8192805 YP_003068486.1 CDS METDI2974 NC_012988.1 2892901 2893158 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2892901..2893158 Methylobacterium extorquens DM4 8192806 YP_003068487.1 CDS METDI2975 NC_012988.1 2893415 2893684 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2893415..2893684 Methylobacterium extorquens DM4 8192807 YP_003068488.1 CDS METDI2976 NC_012988.1 2894008 2895195 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8561793, 8695632; Product type pe : putative enzyme; putative salicylate hydroxylase, Salicylate 1-monooxygenase, nahG complement(2894008..2895195) Methylobacterium extorquens DM4 8196242 YP_003068489.1 CDS METDI2977 NC_012988.1 2895211 2895477 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2895211..2895477) Methylobacterium extorquens DM4 8192809 YP_003068490.1 CDS METDI2978 NC_012988.1 2895864 2896349 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2895864..2896349 Methylobacterium extorquens DM4 8192810 YP_003068491.1 CDS METDI2979 NC_012988.1 2896376 2896582 D Evidence 2b : Function of strongly homologous gene; Product type pr : putative regulator; transcriptional regulator, XRE family 2896376..2896582 Methylobacterium extorquens DM4 8192811 YP_003068492.1 CDS METDI2980 NC_012988.1 2896640 2897911 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2896640..2897911 Methylobacterium extorquens DM4 8192812 YP_003068493.1 CDS map NC_012988.1 2898013 2898867 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10387007, 3027045, 8471602; Product type e : enzyme; methionine aminopeptidase 2898013..2898867 Methylobacterium extorquens DM4 8192813 YP_003068494.1 CDS radC NC_012988.1 2898882 2899628 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10652786, 11743193, 11743194; Product type cp : cell process; DNA repair protein RadC 2898882..2899628 Methylobacterium extorquens DM4 8195661 YP_003068495.1 CDS METDI2983 NC_012988.1 2899944 2901383 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2899944..2901383 Methylobacterium extorquens DM4 8195960 YP_003068496.1 CDS METDI2984 NC_012988.1 2901491 2902435 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2901491..2902435 Methylobacterium extorquens DM4 8192814 YP_003068497.1 CDS METDI2985 NC_012988.1 2902536 2902790 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2902536..2902790) Methylobacterium extorquens DM4 8192815 YP_003068498.1 CDS METDI2986 NC_012988.1 2902831 2903280 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2902831..2903280) Methylobacterium extorquens DM4 8192816 YP_003068499.1 CDS METDI2987 NC_012988.1 2903288 2903665 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2903288..2903665) Methylobacterium extorquens DM4 8192817 YP_003068500.1 CDS METDI2988 NC_012988.1 2903307 2903603 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2903307..2903603 Methylobacterium extorquens DM4 8192818 YP_003068501.1 CDS METDI2989 NC_012988.1 2903894 2904382 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2903894..2904382 Methylobacterium extorquens DM4 8192819 YP_003068502.1 CDS METDI2990 NC_012988.1 2904749 2905639 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Transglutaminase-like domain 2904749..2905639 Methylobacterium extorquens DM4 8192820 YP_003068503.1 CDS METDI2991 NC_012988.1 2905706 2906509 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2905706..2906509 Methylobacterium extorquens DM4 8192821 YP_003068504.1 CDS cobB NC_012988.1 2906624 2907343 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10381378, 10811920, 15019790, 22586414, 8955330, 9822644; Product type e : enzyme; NAD-dependent protein deacetylase, regulatory protein SIR2 family complement(2906624..2907343) Methylobacterium extorquens DM4 8192822 YP_003068505.1 CDS METDI2993 NC_012988.1 2907340 2908554 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative inner membrane protein (UPF0053 family) with 2 CBS domains complement(2907340..2908554) Methylobacterium extorquens DM4 8195183 YP_003068506.1 CDS METDI2994 NC_012988.1 2909033 2912101 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2909033..2912101 Methylobacterium extorquens DM4 8192823 YP_003068507.1 CDS METDI2995 NC_012988.1 2912193 2912423 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2912193..2912423 Methylobacterium extorquens DM4 8192824 YP_003068509.1 CDS METDI2997 NC_012988.1 2912546 2912797 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2912546..2912797) Methylobacterium extorquens DM4 8192826 YP_003068510.1 CDS METDI2998 NC_012988.1 2913082 2914548 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; serine protease precursor complement(2913082..2914548) Methylobacterium extorquens DM4 8192827 YP_003068511.1 CDS METDI2999 NC_012988.1 2914881 2915633 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2914881..2915633) Methylobacterium extorquens DM4 8192828 YP_003068512.1 CDS gap11 NC_012988.1 2915798 2916154 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type f : factor; Granule-associated 11 kDa protein complement(2915798..2916154) Methylobacterium extorquens DM4 8192829 YP_003068513.1 CDS METDI3001 NC_012988.1 2916383 2917687 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase complement(2916383..2917687) Methylobacterium extorquens DM4 8195465 YP_003068514.1 CDS METDI3002 NC_012988.1 2917902 2919173 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase 2917902..2919173 Methylobacterium extorquens DM4 8192830 YP_003068515.1 CDS METDI3003 NC_012988.1 2919261 2919440 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2919261..2919440 Methylobacterium extorquens DM4 8192831 YP_003068516.1 CDS METDI3004 NC_012988.1 2919475 2921808 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL) with PAS sensor complement(2919475..2921808) Methylobacterium extorquens DM4 8192832 YP_003068517.1 CDS msd NC_012988.1 2922033 2923721 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 16856937, 17548827; Product type e : enzyme; methylsuccinyl-CoA dehydrogenase complement(2922033..2923721) Methylobacterium extorquens DM4 8192833 YP_003068518.1 CDS METDI3006 NC_012988.1 2923884 2924774 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2923884..2924774) Methylobacterium extorquens DM4 8195726 YP_003068519.1 CDS METDI3007 NC_012988.1 2924927 2925829 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ribonuclease RNAse BN 2924927..2925829 Methylobacterium extorquens DM4 8192834 YP_003068520.1 CDS METDI3008 NC_012988.1 2925741 2926781 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2925741..2926781) Methylobacterium extorquens DM4 8192835 YP_003068521.1 CDS cysN NC_012988.1 2926967 2928376 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1316900, 2828368, 88115389, 92112707, 92268080; Product type e : enzyme; ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase) complement(2926967..2928376) Methylobacterium extorquens DM4 8192836 YP_003068522.1 CDS cysD NC_012988.1 2928376 2929305 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(2928376..2929305) Methylobacterium extorquens DM4 8195259 YP_003068523.1 CDS cysH NC_012988.1 2929305 2930114 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10464198, 11481430; Product type e : enzyme; Phosphoadenosine phosphosulfate reductase (PAPS reductase, thioredoxin dependent) (PAdoPS reductase) (3'-phosphoadenylyl-sulfate reductase) (PAPS sulfotransferase) complement(2929305..2930114) Methylobacterium extorquens DM4 8195250 YP_003068524.1 CDS METDI3012 NC_012988.1 2930379 2930882 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, AsnC/Lrp family 2930379..2930882 Methylobacterium extorquens DM4 8195254 YP_003068525.1 CDS cysJ NC_012988.1 2930995 2932770 D Evidence 2b : Function of strongly homologous gene; PubMedId : 16738553, 2550423, 2670946, 7589518, 7657631, 9153434, 9278503, 9618257; Product type e : enzyme; sulfite reductase, alpha subunit (flavoprotein) 2930995..2932770 Methylobacterium extorquens DM4 8192837 YP_003068526.1 CDS cysI NC_012988.1 2932957 2934795 D hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 2932957..2934795 Methylobacterium extorquens DM4 8195256 YP_003068527.1 CDS METDI3015 NC_012988.1 2934859 2937039 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent receptor complement(2934859..2937039) Methylobacterium extorquens DM4 8195255 YP_003068528.1 CDS panC NC_012988.1 2937374 2938231 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(2937374..2938231) Methylobacterium extorquens DM4 8192838 YP_003068529.1 CDS METDI3017 NC_012988.1 2938307 2938666 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2938307..2938666) Methylobacterium extorquens DM4 8195824 YP_003068530.1 CDS METDI3018 NC_012988.1 2938739 2939344 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, XRE family complement(2938739..2939344) Methylobacterium extorquens DM4 8192839 YP_003068531.1 CDS ssb NC_012988.1 2939721 2940287 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type cp : cell process; Single-stranded DNA-binding protein complement(2939721..2940287) Methylobacterium extorquens DM4 8192840 YP_003068532.1 CDS yncB NC_012988.1 2940592 2941608 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative conserved oxidoreductase, Zn-dependent and NAD(P)-binding complement(2940592..2941608) Methylobacterium extorquens DM4 8196147 YP_003068533.1 CDS METDI3022 NC_012988.1 2941701 2942108 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2941701..2942108 Methylobacterium extorquens DM4 8196375 YP_003068534.1 CDS METDI3023 NC_012988.1 2942161 2942700 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2942161..2942700) Methylobacterium extorquens DM4 8192841 YP_003068535.1 CDS METDI3024 NC_012988.1 2942927 2943703 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2942927..2943703 Methylobacterium extorquens DM4 8192842 YP_003068536.1 CDS METDI3025 NC_012988.1 2943862 2944980 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16109935; Product type pe : putative enzyme; putative NADH:flavin oxidoreductase/NADH oxidase complement(2943862..2944980) Methylobacterium extorquens DM4 8192843 YP_003068537.1 CDS METDI3028 NC_012988.1 2946211 2946726 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2946211..2946726 Methylobacterium extorquens DM4 8192846 YP_003068538.1 CDS trx NC_012988.1 2946963 2947871 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; thioredoxin 2946963..2947871 Methylobacterium extorquens DM4 8192847 YP_003068539.1 CDS METDI3030 NC_012988.1 2947957 2948625 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10583374, 10877760, 12123452; Product type pe : putative enzyme; putative Lon family ATP-dependent protease 2947957..2948625 Methylobacterium extorquens DM4 8196283 YP_003068540.1 CDS METDI3031 NC_012988.1 2948683 2948889 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2948683..2948889 Methylobacterium extorquens DM4 8192848 YP_003068541.1 CDS METDI3032 NC_012988.1 2949044 2950003 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2949044..2950003) Methylobacterium extorquens DM4 8192849 YP_003068542.1 CDS METDI3033 NC_012988.1 2949783 2950079 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2949783..2950079 Methylobacterium extorquens DM4 8192850 YP_003068543.1 CDS METDI3034 NC_012988.1 2950204 2951319 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2950204..2951319) Methylobacterium extorquens DM4 8192851 YP_003068544.1 CDS METDI3035 NC_012988.1 2951441 2952145 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2951441..2952145) Methylobacterium extorquens DM4 8192852 YP_003068545.1 CDS METDI3036 NC_012988.1 2952352 2953011 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transglutaminase-like cysteine peptidase precursor complement(2952352..2953011) Methylobacterium extorquens DM4 8192853 YP_003068546.1 CDS METDI3037 NC_012988.1 2953455 2954054 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2953455..2954054) Methylobacterium extorquens DM4 8192854 YP_003068547.1 CDS METDI3038 NC_012988.1 2954287 2954919 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2954287..2954919) Methylobacterium extorquens DM4 8192855 YP_003068548.1 CDS METDI3039 NC_012988.1 2955148 2955972 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative rhomboid-like protein 2955148..2955972 Methylobacterium extorquens DM4 8192856 YP_003068549.1 CDS METDI3040 NC_012988.1 2956214 2956654 D Evidence 6 : Doubtful CDS; hypothetical protein 2956214..2956654 Methylobacterium extorquens DM4 8192857 YP_003068550.1 CDS METDI3041 NC_012988.1 2956270 2957100 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10433972; Product type pf : putative factor; putative CoxB-related 2956270..2957100 Methylobacterium extorquens DM4 8192858 YP_003068551.1 CDS METDI3042 NC_012988.1 2957072 2957368 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2957072..2957368) Methylobacterium extorquens DM4 8192859 YP_003068552.1 CDS METDI3043 NC_012988.1 2957459 2957890 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2957459..2957890 Methylobacterium extorquens DM4 8192860 YP_003068553.1 CDS METDI3044 NC_012988.1 2957943 2959001 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative patatin-like esterase complement(2957943..2959001) Methylobacterium extorquens DM4 8192861 YP_003068554.1 CDS hisI NC_012988.1 2958998 2959420 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; phosphoribosyl c-AMP cyclohydrolase complement(2958998..2959420) Methylobacterium extorquens DM4 8192862 YP_003068555.1 CDS folE NC_012988.1 2959440 2960249 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12730156; Product type e : enzyme; GTP cyclohydrolase I complement(2959440..2960249) Methylobacterium extorquens DM4 8195565 YP_003068556.1 CDS METDI3048 NC_012988.1 2960473 2960946 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2960473..2960946 Methylobacterium extorquens DM4 8195437 YP_003068557.1 CDS METDI3049 NC_012988.1 2961018 2961338 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2961018..2961338 Methylobacterium extorquens DM4 8192863 YP_003068558.1 CDS ybhL NC_012988.1 2961496 2962263 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pt : putative transporter; hypothetical protein complement(2961496..2962263) Methylobacterium extorquens DM4 8192864 YP_003068559.1 CDS METDI3051 NC_012988.1 2962481 2965063 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2962481..2965063) Methylobacterium extorquens DM4 8196352 YP_003068560.1 CDS METDI3052 NC_012988.1 2965176 2966591 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase precursor complement(2965176..2966591) Methylobacterium extorquens DM4 8192865 YP_003068561.1 CDS pdxJ NC_012988.1 2966733 2967482 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2966733..2967482 Methylobacterium extorquens DM4 8192866 YP_003068562.1 CDS acpS NC_012988.1 2967479 2967889 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2967479..2967889 Methylobacterium extorquens DM4 8195842 YP_003068563.1 CDS METDI3055 NC_012988.1 2968019 2968825 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9870699; Product type e : enzyme; signal peptidase I (SPase I) (leader peptidase I) 2968019..2968825 Methylobacterium extorquens DM4 8195051 YP_003068564.1 CDS rnc NC_012988.1 2968886 2969656 D Evidence 2b : Function of strongly homologous gene; PubMedId : 14704707; Product type e : enzyme; ribonuclease III 2968886..2969656 Methylobacterium extorquens DM4 8192867 YP_003068565.1 CDS era NC_012988.1 2969677 2970657 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275, 9870699; Product type e : enzyme; GTP-binding protein 2969677..2970657 Methylobacterium extorquens DM4 8196001 YP_003068566.1 CDS METDI3058 NC_012988.1 2970853 2971779 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase 2970853..2971779 Methylobacterium extorquens DM4 8195332 YP_003068567.1 CDS rsuA NC_012988.1 2971776 2972504 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10376875, 11953756, 7612632; Product type e : enzyme; 16S rRNA pseudouridylate 516 synthase 2971776..2972504 Methylobacterium extorquens DM4 8192868 YP_003068568.1 CDS METDI3060 NC_012988.1 2972509 2973150 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2972509..2973150) Methylobacterium extorquens DM4 8196090 YP_003068569.1 CDS METDI3061 NC_012988.1 2973374 2974768 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2973374..2974768 Methylobacterium extorquens DM4 8192869 YP_003068570.1 CDS METDI3062 NC_012988.1 2974969 2975760 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2974969..2975760 Methylobacterium extorquens DM4 8192870 YP_003068571.1 CDS METDI3063 NC_012988.1 2975971 2976276 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2975971..2976276 Methylobacterium extorquens DM4 8192871 YP_003068572.1 CDS kup1 NC_012988.1 2976284 2978212 R Evidence 2b : Function of strongly homologous gene; PubMedId : 89197799, 94042856, 99229748; Product type t : transporter; potassium uptake protein Kup complement(2976284..2978212) Methylobacterium extorquens DM4 8192872 YP_003068573.1 CDS METDI3065 NC_012988.1 2978412 2979068 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2978412..2979068) Methylobacterium extorquens DM4 8195625 YP_003068574.1 CDS METDI3066 NC_012988.1 2979096 2979683 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10760174, 11479323, 14594825, 21474313; Product type pe : putative enzyme; (di)nucleoside polyphosphate hydrolase (Nudix family) complement(2979096..2979683) Methylobacterium extorquens DM4 8192873 YP_003068575.1 CDS METDI3067 NC_012988.1 2979828 2981516 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative methyl-accepting chemotaxis sensory transducer complement(2979828..2981516) Methylobacterium extorquens DM4 8192874 YP_003068576.1 CDS METDI3068 NC_012988.1 2981877 2983106 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2981877..2983106) Methylobacterium extorquens DM4 8192875 YP_003068577.1 CDS METDI3069 NC_012988.1 2983234 2984595 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative periplasmic carboxyl-terminal processing protease complement(2983234..2984595) Methylobacterium extorquens DM4 8192876 YP_003068578.1 CDS METDI3070 NC_012988.1 2984556 2985956 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-bound metallopeptidase complement(2984556..2985956) Methylobacterium extorquens DM4 8192877 YP_003068579.1 CDS METDI3071 NC_012988.1 2985953 2986450 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2985953..2986450) Methylobacterium extorquens DM4 8192878 YP_003068580.1 CDS METDI3072 NC_012988.1 2986698 2988008 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; MFS transporter membrane protein 2986698..2988008 Methylobacterium extorquens DM4 8192879 YP_003068581.1 CDS METDI3073 NC_012988.1 2988289 2990238 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase/phosphodiesterase (GGDEF and EAL motifs) 2988289..2990238 Methylobacterium extorquens DM4 8192880 YP_003068582.1 CDS METDI3074 NC_012988.1 2990243 2990869 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; periplasmic oxidoreductase, DsbA family complement(2990243..2990869) Methylobacterium extorquens DM4 8192881 YP_003068583.1 CDS argG NC_012988.1 2991044 2992285 D catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 2991044..2992285 Methylobacterium extorquens DM4 8192882 YP_003068584.1 CDS METDI3076 NC_012988.1 2992488 2992772 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2992488..2992772) Methylobacterium extorquens DM4 8195088 YP_003068585.1 CDS METDI3077 NC_012988.1 2992859 2993524 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2992859..2993524) Methylobacterium extorquens DM4 8192883 YP_003068586.1 CDS METDI3078 NC_012988.1 2993720 2994421 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226680, 9006018; Product type pe : putative enzyme; putative haloacid dehalogenase family hydrolase complement(2993720..2994421) Methylobacterium extorquens DM4 8192884 YP_003068587.1 CDS METDI3079 NC_012988.1 2994617 2995114 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2994617..2995114 Methylobacterium extorquens DM4 8192885 YP_003068588.1 CDS rpiA NC_012988.1 2995295 2996005 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12517338, 8366047; Product type e : enzyme; Ribose-5-phosphate isomerase A 2995295..2996005 Methylobacterium extorquens DM4 8192886 YP_003068589.1 CDS METDI3081 NC_012988.1 2996047 2996643 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2996047..2996643 Methylobacterium extorquens DM4 8196011 YP_003068590.1 CDS METDI3082 NC_012988.1 2996815 2997984 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2996815..2997984 Methylobacterium extorquens DM4 8192887 YP_003068591.1 CDS gor NC_012988.1 2997981 2999381 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1849605; Product type e : enzyme; glutathione reductase 2997981..2999381 Methylobacterium extorquens DM4 8192888 YP_003068592.1 CDS METDI3084 NC_012988.1 2999383 3000807 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2999383..3000807) Methylobacterium extorquens DM4 8195527 YP_003068593.1 CDS METDI3085 NC_012988.1 3001041 3001523 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3001041..3001523 Methylobacterium extorquens DM4 8192889 YP_003068594.1 CDS osmC NC_012988.1 3001609 3002040 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15188393, 16926146, 1715407; Product type m : membrane component; osmotically inducible protein OsmC 3001609..3002040 Methylobacterium extorquens DM4 8192890 YP_003068595.1 CDS METDI3087 NC_012988.1 3002147 3003358 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3002147..3003358 Methylobacterium extorquens DM4 8195813 YP_003068596.1 CDS ung NC_012988.1 3003358 3004815 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Uracil-DNA glycosylase superfamily protein (DNA replication, recombination and repair) 3003358..3004815 Methylobacterium extorquens DM4 8192891 YP_003068597.1 CDS METDI3089 NC_012988.1 3005099 3006271 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative zinc-containing alcohol dehydrogenase 3005099..3006271 Methylobacterium extorquens DM4 8196304 YP_003068598.1 CDS METDI3090 NC_012988.1 3006414 3006998 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3006414..3006998 Methylobacterium extorquens DM4 8192892 YP_003068599.1 CDS METDI3091 NC_012988.1 3007056 3008753 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3007056..3008753) Methylobacterium extorquens DM4 8192893 YP_003068600.1 CDS METDI3092 NC_012988.1 3008750 3009868 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3008750..3009868) Methylobacterium extorquens DM4 8192894 YP_003068601.1 CDS METDI3093 NC_012988.1 3010048 3010710 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3010048..3010710 Methylobacterium extorquens DM4 8192895 YP_003068602.1 CDS METDI3094 NC_012988.1 3010749 3011336 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase 3010749..3011336 Methylobacterium extorquens DM4 8192896 YP_003068603.1 CDS METDI3095 NC_012988.1 3011495 3011749 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3011495..3011749 Methylobacterium extorquens DM4 8192897 YP_003068604.1 CDS METDI3096 NC_012988.1 3011923 3012915 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative catalase precursor 3011923..3012915 Methylobacterium extorquens DM4 8192898 YP_003068605.1 CDS METDI3097 NC_012988.1 3013348 3013953 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3013348..3013953) Methylobacterium extorquens DM4 8192899 YP_003068606.1 CDS METDI3098 NC_012988.1 3013964 3014551 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Nitroreductase family protein complement(3013964..3014551) Methylobacterium extorquens DM4 8192900 YP_003068607.1 CDS METDI3099 NC_012988.1 3014708 3015640 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3014708..3015640 Methylobacterium extorquens DM4 8192901 YP_003068608.1 CDS METDI3100 NC_012988.1 3015646 3016038 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3015646..3016038 Methylobacterium extorquens DM4 8192902 YP_003068609.1 CDS METDI3101 NC_012988.1 3016245 3016376 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3016245..3016376) Methylobacterium extorquens DM4 8192903 YP_003068610.1 CDS METDI3102 NC_012988.1 3016503 3017897 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator (GntR family) 3016503..3017897 Methylobacterium extorquens DM4 8192904 YP_003068611.1 CDS thrS NC_012988.1 3017928 3019955 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(3017928..3019955) Methylobacterium extorquens DM4 8192905 YP_003068612.1 CDS METDI3104 NC_012988.1 3020121 3020873 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3020121..3020873) Methylobacterium extorquens DM4 8196195 YP_003068613.1 CDS METDI3105 NC_012988.1 3020870 3021772 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11742072; Product type pe : putative enzyme; putative kinase (mak-like) /transcriptional regulator, actin-like ATPase domain (NagC/XylR (ROK) familiy) complement(3020870..3021772) Methylobacterium extorquens DM4 8192906 YP_003068614.1 CDS dctA NC_012988.1 3021795 3023123 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10482502, 4568614; Product type t : transporter; sodium:dicarboxylate symporter (DAACS family) complement(3021795..3023123) Methylobacterium extorquens DM4 8192907 YP_003068615.1 CDS ileS NC_012988.1 3023675 3026650 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 3023675..3026650 Methylobacterium extorquens DM4 8195279 YP_003068616.1 CDS lspA NC_012988.1 3026647 3027162 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 3026647..3027162 Methylobacterium extorquens DM4 8195591 YP_003068617.1 CDS METDI3109 NC_012988.1 3027325 3028029 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3027325..3028029 Methylobacterium extorquens DM4 8195653 YP_003068618.1 CDS pqqF NC_012988.1 3028223 3029605 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; putative protease 3028223..3029605 Methylobacterium extorquens DM4 8192908 YP_003068619.1 CDS pqqG NC_012988.1 3029677 3030960 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; putative protease 3029677..3030960 Methylobacterium extorquens DM4 8195892 YP_003068620.1 CDS METDI3112 NC_012988.1 3031147 3032079 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10542173; Product type pe : putative enzyme; putative linE 3031147..3032079 Methylobacterium extorquens DM4 8195893 YP_003068621.1 CDS fpr NC_012988.1 3032249 3033022 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8034707, 9865948; Product type e : enzyme; ferredoxin--NADP+ reductase 3032249..3033022 Methylobacterium extorquens DM4 8192909 YP_003068622.1 CDS bioD NC_012988.1 3033316 3033993 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11259647; Product type e : enzyme; Dethiobiotin synthetase (Dethiobiotin synthase) (DTB synthetase) (DTBS) 3033316..3033993 Methylobacterium extorquens DM4 8195441 YP_003068623.1 CDS METDI3115 NC_012988.1 3034000 3034359 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3034000..3034359) Methylobacterium extorquens DM4 8195144 YP_003068624.1 CDS METDI3116 NC_012988.1 3034393 3034812 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Response regulator receiver domain (cheY-like protein) complement(3034393..3034812) Methylobacterium extorquens DM4 8192910 YP_003068625.1 CDS METDI3117 NC_012988.1 3035080 3035754 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3035080..3035754 Methylobacterium extorquens DM4 8192911 YP_003068626.1 CDS METDI3118 NC_012988.1 3035772 3036779 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; WD-40 repeat family protein 3035772..3036779 Methylobacterium extorquens DM4 8192912 YP_003068627.1 CDS METDI3119 NC_012988.1 3036790 3037050 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3036790..3037050 Methylobacterium extorquens DM4 8192913 YP_003068628.1 CDS METDI3120 NC_012988.1 3037117 3037647 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3037117..3037647 Methylobacterium extorquens DM4 8192914 YP_003068629.1 CDS METDI3121 NC_012988.1 3037777 3039009 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3037777..3039009 Methylobacterium extorquens DM4 8192915 YP_003068630.1 CDS METDI3122 NC_012988.1 3039014 3039454 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3039014..3039454) Methylobacterium extorquens DM4 8192916 YP_003068631.1 CDS METDI3123 NC_012988.1 3039451 3040197 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Pyrimidine 5-nucleotidase (HAD-superfamily hydrolase) complement(3039451..3040197) Methylobacterium extorquens DM4 8192917 YP_003068632.1 CDS argB NC_012988.1 3040285 3041181 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; acetylglutamate kinase complement(3040285..3041181) Methylobacterium extorquens DM4 8192918 YP_003068633.1 CDS METDI3125 NC_012988.1 3041581 3041805 D Evidence 6 : Doubtful CDS; hypothetical protein 3041581..3041805 Methylobacterium extorquens DM4 8195083 YP_003068634.1 CDS METDI3126 NC_012988.1 3041827 3042603 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; MOSC (sulfur-carrier) domain protein complement(3041827..3042603) Methylobacterium extorquens DM4 8192919 YP_003068635.1 CDS METDI3127 NC_012988.1 3042740 3043534 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; MOSC (sulfur-carrier) domain protein 3042740..3043534 Methylobacterium extorquens DM4 8192920 YP_003068636.1 CDS clpB NC_012988.1 3043763 3046387 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; protein disaggregation chaperone 3043763..3046387 Methylobacterium extorquens DM4 8192921 YP_003068637.1 CDS METDI3129 NC_012988.1 3046565 3047239 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Metallophosphoesterase 3046565..3047239 Methylobacterium extorquens DM4 8195171 YP_003068638.1 CDS atoE NC_012988.1 3047367 3048806 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; short-chain fatty acid transporter (scFAT family) 3047367..3048806 Methylobacterium extorquens DM4 8192922 YP_003068639.1 CDS METDI3131 NC_012988.1 3048814 3049032 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3048814..3049032) Methylobacterium extorquens DM4 8195115 YP_003068640.1 CDS METDI3132 NC_012988.1 3049067 3049438 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3049067..3049438) Methylobacterium extorquens DM4 8192923 YP_003068641.1 CDS engB NC_012988.1 3049435 3050094 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(3049435..3050094) Methylobacterium extorquens DM4 8192924 YP_003068642.1 CDS oxaA NC_012988.1 3050342 3052255 R Evidence 2b : Function of strongly homologous gene; PubMedId : 17922846; Product type m : membrane component; transmembrane protein, OxaA-like, preprotein translocase component complement(3050342..3052255) Methylobacterium extorquens DM4 8192925 YP_003068643.1 CDS rnpA NC_012988.1 3052185 3052682 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ribonuclease P protein component (RNaseP protein, RNase P protein, protein C5) complement(3052185..3052682) Methylobacterium extorquens DM4 8195815 YP_003068644.1 CDS METDI3136 NC_012988.1 3053017 3053241 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3053017..3053241 Methylobacterium extorquens DM4 8196006 YP_003068645.1 CDS METDI3137 NC_012988.1 3053562 3054095 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, AraC family 3053562..3054095 Methylobacterium extorquens DM4 8192926 YP_003068646.1 CDS rpmE NC_012988.1 3054429 3054683 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; 50S ribosomal protein L31 complement(3054429..3054683) Methylobacterium extorquens DM4 8192927 YP_003068647.1 CDS METDI3139 NC_012988.1 3054976 3056835 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter related, fused ATPase and transmembrane permease domains 3054976..3056835 Methylobacterium extorquens DM4 8196039 YP_003068648.1 CDS dcyD NC_012988.1 3056969 3057976 D catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 3056969..3057976 Methylobacterium extorquens DM4 8192928 YP_003068649.1 CDS motB NC_012988.1 3058016 3059029 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; flagellar motor protein MotB complement(3058016..3059029) Methylobacterium extorquens DM4 8195282 YP_003068650.1 CDS METDI3142 NC_012988.1 3059030 3060025 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3059030..3060025) Methylobacterium extorquens DM4 8195718 YP_003068651.1 CDS METDI3143 NC_012988.1 3060187 3061008 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3060187..3061008) Methylobacterium extorquens DM4 8192929 YP_003068652.1 CDS METDI3144 NC_012988.1 3061074 3061664 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ligase (ygfA) complement(3061074..3061664) Methylobacterium extorquens DM4 8192930 YP_003068653.1 CDS METDI3145 NC_012988.1 3061912 3062283 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3061912..3062283) Methylobacterium extorquens DM4 8192931 YP_003068654.1 CDS METDI3146 NC_012988.1 3062307 3062627 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3062307..3062627) Methylobacterium extorquens DM4 8192932 YP_003068655.1 CDS gapA NC_012988.1 3063090 3064097 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10799476, 7751290; Product type e : enzyme; Glyceraldehyde-3-phosphate dehydrogenase 3063090..3064097 Methylobacterium extorquens DM4 8192933 YP_003068656.1 CDS METDI3148 NC_012988.1 3064292 3064798 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3064292..3064798 Methylobacterium extorquens DM4 8195467 YP_003068657.1 CDS pgk NC_012988.1 3064814 3066016 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1433299; Product type e : enzyme; phosphoglycerate kinase 3064814..3066016 Methylobacterium extorquens DM4 8192934 YP_003068658.1 CDS cbbA NC_012988.1 3066169 3067236 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 3066169..3067236 Methylobacterium extorquens DM4 8195849 YP_003068659.1 CDS METDI3151 NC_012988.1 3067243 3067911 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thiamine-phosphate pyrophosphorylase (TMP pyrophosphorylase) (TMP-PPase) (thiamine-phosphate synthase) 3067243..3067911 Methylobacterium extorquens DM4 8195149 YP_003068660.1 CDS METDI3152 NC_012988.1 3067908 3069056 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Sel1-like repeats containing protein 3067908..3069056 Methylobacterium extorquens DM4 8192935 YP_003068661.1 CDS METDI3153 NC_012988.1 3069286 3070695 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino acid permease 3069286..3070695 Methylobacterium extorquens DM4 8192936 YP_003068662.1 CDS METDI3154 NC_012988.1 3070705 3072228 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carbohydrate kinase complement(3070705..3072228) Methylobacterium extorquens DM4 8192937 YP_003068663.1 CDS glnB NC_012988.1 3072413 3072751 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; regulatory protein (P-II) for nitrogen assimilation by glutamine synthetase (ATase) 3072413..3072751 Methylobacterium extorquens DM4 8192938 YP_003068664.1 CDS glsA NC_012988.1 3072838 3073767 D catalyzes the formation of glutamate from glutamine; glutaminase 3072838..3073767 Methylobacterium extorquens DM4 8195498 YP_003068665.1 CDS glnII NC_012988.1 3074008 3075054 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1355107; Product type e : enzyme; glutamine synthetase II complement(3074008..3075054) Methylobacterium extorquens DM4 8195510 YP_003068666.1 CDS glnA NC_012988.1 3075630 3077039 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2882477; Product type e : enzyme; glutamine synthetase, type I 3075630..3077039 Methylobacterium extorquens DM4 8195503 YP_003068667.1 CDS METDI3159 NC_012988.1 3077172 3077750 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADPH-dependent FMN reductase 3077172..3077750 Methylobacterium extorquens DM4 8195497 YP_003068668.1 CDS METDI3160 NC_012988.1 3077895 3078233 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3077895..3078233 Methylobacterium extorquens DM4 8192939 YP_003068669.1 CDS METDI3161 NC_012988.1 3078167 3078280 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3078167..3078280 Methylobacterium extorquens DM4 8192940 YP_003068670.1 CDS RNR NC_012988.1 3078392 3080758 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ribonuclease R 3078392..3080758 Methylobacterium extorquens DM4 8192941 YP_003068671.1 CDS METDI3163 NC_012988.1 3080782 3081279 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3080782..3081279 Methylobacterium extorquens DM4 8196007 YP_003068672.1 CDS METDI3164 NC_012988.1 3081320 3082003 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NUDIX hydrolase 3081320..3082003 Methylobacterium extorquens DM4 8192942 YP_003068673.1 CDS METDI3165 NC_012988.1 3082125 3084089 D Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; methyl-accepting chemotaxis receptor/sensory transducer with PAS domain 3082125..3084089 Methylobacterium extorquens DM4 8192943 YP_003068674.1 CDS METDI3166 NC_012988.1 3084149 3085018 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative epimerase with NAD(P)-binding Rossmann-fold domain (yeeZ-like) complement(3084149..3085018) Methylobacterium extorquens DM4 8192944 YP_003068675.1 CDS METDI3167 NC_012988.1 3085025 3086329 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative iron-sulfur cluster binding protein complement(3085025..3086329) Methylobacterium extorquens DM4 8192945 YP_003068676.1 CDS METDI3168 NC_012988.1 3086200 3086892 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(3086200..3086892) Methylobacterium extorquens DM4 8192946 YP_003068677.1 CDS bacA NC_012988.1 3087120 3087971 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11743193, 11743194; Product type e : enzyme; Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) (Bacitracin resistance protein) 3087120..3087971 Methylobacterium extorquens DM4 8192947 YP_003068678.1 CDS mcmB NC_012988.1 3088120 3089937 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14734568; Product type e : enzyme; methylmalonyl-CoA beta subunit 3088120..3089937 Methylobacterium extorquens DM4 8195124 YP_003068679.1 CDS METDI3171 NC_012988.1 3090045 3090437 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3090045..3090437 Methylobacterium extorquens DM4 8195669 YP_003068680.1 CDS METDI3172 NC_012988.1 3090624 3091079 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3090624..3091079 Methylobacterium extorquens DM4 8192948 YP_003068681.1 CDS METDI3173 NC_012988.1 3091102 3091545 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3091102..3091545) Methylobacterium extorquens DM4 8192949 YP_003068682.1 CDS rfbC NC_012988.1 3091731 3092282 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1710759; Product type e : enzyme; dTDP-4-dehydrorhamnose 3,5-epimerase 3091731..3092282 Methylobacterium extorquens DM4 8192950 YP_003068683.1 CDS rffG NC_012988.1 3092416 3093474 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7559340; Product type e : enzyme; dTDP-glucose 4,6-dehydratase 3092416..3093474 Methylobacterium extorquens DM4 8195983 YP_003068684.1 CDS rfbD NC_012988.1 3093477 3094367 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; dTDP-4-dehydrorhamnose reductase 3093477..3094367 Methylobacterium extorquens DM4 8195987 YP_003068685.1 CDS rffH NC_012988.1 3094384 3095274 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7559340; Product type e : enzyme; Glucose-1-phosphate thymidylyltransferase 3094384..3095274 Methylobacterium extorquens DM4 8195984 YP_003068686.1 CDS METDI3178 NC_012988.1 3095407 3096066 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3095407..3096066) Methylobacterium extorquens DM4 8195988 YP_003068687.1 CDS METDI3179 NC_012988.1 3096136 3097017 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3096136..3097017) Methylobacterium extorquens DM4 8192951 YP_003068688.1 CDS secA NC_012988.1 3097031 3099067 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA complement(3097031..3099067) Methylobacterium extorquens DM4 8192952 YP_003068689.1 CDS METDI3181 NC_012988.1 3099060 3100154 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3099060..3100154) Methylobacterium extorquens DM4 8192953 YP_003068690.1 CDS METDI3182 NC_012988.1 3100250 3100999 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3100250..3100999 Methylobacterium extorquens DM4 8192954 YP_003068691.1 CDS METDI3183 NC_012988.1 3101107 3102546 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative multicopper oxidase complement(3101107..3102546) Methylobacterium extorquens DM4 8192955 YP_003068692.1 CDS tig NC_012988.1 3102927 3104363 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 3102927..3104363 Methylobacterium extorquens DM4 8196239 YP_003068693.1 CDS clpP NC_012988.1 3104495 3105121 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 3104495..3105121 Methylobacterium extorquens DM4 8196197 YP_003068694.1 CDS clpX NC_012988.1 3105373 3106644 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 3105373..3106644 Methylobacterium extorquens DM4 8195172 YP_003068695.1 CDS lon NC_012988.1 3106912 3109332 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10877760, 12123452, 14764100; Product type e : enzyme; ATP-dependent protease La (Lon) 3106912..3109332 Methylobacterium extorquens DM4 8195174 YP_003068696.1 CDS METDI3188 NC_012988.1 3109923 3110159 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3109923..3110159) Methylobacterium extorquens DM4 8196267 YP_003068697.1 CDS METDI3189 NC_012988.1 3110487 3111725 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glycosyl transferase, group 1 3110487..3111725 Methylobacterium extorquens DM4 8192957 YP_003068698.1 CDS METDI3190 NC_012988.1 3111737 3112684 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3111737..3112684) Methylobacterium extorquens DM4 8192958 YP_003068699.1 CDS METDI3191 NC_012988.1 3112681 3113706 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3112681..3113706) Methylobacterium extorquens DM4 8192959 YP_003068700.1 CDS METDI3192 NC_012988.1 3113709 3114464 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3113709..3114464) Methylobacterium extorquens DM4 8192960 YP_003068701.1 CDS METDI3193 NC_012988.1 3114741 3115337 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3114741..3115337) Methylobacterium extorquens DM4 8192961 YP_003068702.1 CDS METDI3194 NC_012988.1 3115510 3117525 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide transporter, OPT superfamily 3115510..3117525 Methylobacterium extorquens DM4 8192962 YP_003068703.1 CDS METDI3195 NC_012988.1 3117594 3118388 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC-2 transporter, permease 3117594..3118388 Methylobacterium extorquens DM4 8192963 YP_003068704.1 CDS METDI3196 NC_012988.1 3118978 3119679 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3118978..3119679) Methylobacterium extorquens DM4 8196214 YP_003068705.1 CDS METDI3197 NC_012988.1 3119915 3121108 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Ribonuclease BN family protein 3119915..3121108 Methylobacterium extorquens DM4 8192965 YP_003068706.1 CDS METDI3198 NC_012988.1 3121456 3121848 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3121456..3121848) Methylobacterium extorquens DM4 8192966 YP_003068707.1 CDS polA NC_012988.1 3122353 3125496 D Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 10986246; Product type e : enzyme; DNA polymerase I 3122353..3125496 Methylobacterium extorquens DM4 8192967 YP_003068708.1 CDS nfi NC_012988.1 3126542 3127204 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20075121, 6246346, 8206931, 8990280, 9388217, 97144513; Product type e : enzyme; Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V) (DNase V) complement(3126542..3127204) Methylobacterium extorquens DM4 8195874 YP_003068709.1 CDS ychF NC_012988.1 3127218 3128315 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(3127218..3128315) Methylobacterium extorquens DM4 8195776 YP_003068710.1 CDS pth NC_012988.1 3128395 3129027 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(3128395..3129027) Methylobacterium extorquens DM4 8196356 YP_003068711.1 CDS rplY NC_012988.1 3129129 3129815 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc complement(3129129..3129815) Methylobacterium extorquens DM4 8195915 YP_003068712.1 CDS METDI3204 NC_012988.1 3130096 3130578 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3130096..3130578) Methylobacterium extorquens DM4 8196034 YP_003068713.1 CDS METDI3205 NC_012988.1 3130931 3131137 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10880436; Product type f : factor; Flp/Fap pilin component 3130931..3131137 Methylobacterium extorquens DM4 8192968 YP_003068714.1 CDS cpaA NC_012988.1 3131336 3131854 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; type IV prepilin peptidase, cpaA 3131336..3131854 Methylobacterium extorquens DM4 8192969 YP_003068715.1 CDS cpaB NC_012988.1 3132047 3132832 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; pilus assembly protein cpaB 3132047..3132832 Methylobacterium extorquens DM4 8195209 YP_003068716.1 CDS METDI3208 NC_012988.1 3132844 3134352 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative pilus assembly protein; putative precursor 3132844..3134352 Methylobacterium extorquens DM4 8195210 YP_003068717.1 CDS cpaD NC_012988.1 3134378 3135124 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; pilus assembly protein cpaD 3134378..3135124 Methylobacterium extorquens DM4 8192970 YP_003068718.1 CDS cpaE NC_012988.1 3135210 3136454 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; pilus assembly protein cpaE 3135210..3136454 Methylobacterium extorquens DM4 8195211 YP_003068719.1 CDS cpaF NC_012988.1 3136502 3137950 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; secretory protein kinase, cpaF 3136502..3137950 Methylobacterium extorquens DM4 8195212 YP_003068720.1 CDS METDI3212 NC_012988.1 3137947 3138918 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Pilus assembly protein, type II secretion protein 3137947..3138918 Methylobacterium extorquens DM4 8195213 YP_003068721.1 CDS METDI3213 NC_012988.1 3138967 3139938 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3138967..3139938 Methylobacterium extorquens DM4 8192971 YP_003068722.1 CDS METDI3214 NC_012988.1 3140039 3141037 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3140039..3141037 Methylobacterium extorquens DM4 8192972 YP_003068723.1 CDS METDI3215 NC_012988.1 3141034 3142296 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS transporter membrane protein 3141034..3142296 Methylobacterium extorquens DM4 8192973 YP_003068724.1 CDS ohr NC_012988.1 3142438 3142863 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; organic hydroperoxide resistance protein 3142438..3142863 Methylobacterium extorquens DM4 8192974 YP_003068725.1 CDS METDI3217 NC_012988.1 3143013 3143594 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; CoA Binding Domain protein complement(3143013..3143594) Methylobacterium extorquens DM4 8195804 YP_003068726.1 CDS METDI3218 NC_012988.1 3143621 3144052 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3143621..3144052 Methylobacterium extorquens DM4 8192975 YP_003068727.1 CDS METDI3219 NC_012988.1 3144108 3145427 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Major Facilitator Superfamily (MFS) transporter complement(3144108..3145427) Methylobacterium extorquens DM4 8192976 YP_003068728.1 CDS METDI3220 NC_012988.1 3145827 3147323 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase with GGDEF motif; putative membrane protein 3145827..3147323 Methylobacterium extorquens DM4 8192977 YP_003068729.1 CDS METDI3221 NC_012988.1 3147396 3147815 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3147396..3147815) Methylobacterium extorquens DM4 8192978 YP_003068730.1 CDS METDI3222 NC_012988.1 3147945 3148856 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3147945..3148856) Methylobacterium extorquens DM4 8192979 YP_003068731.1 CDS METDI3223 NC_012988.1 3148904 3149236 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3148904..3149236) Methylobacterium extorquens DM4 8192980 YP_003068732.1 CDS METDI3224 NC_012988.1 3149554 3149919 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3149554..3149919 Methylobacterium extorquens DM4 8192981 YP_003068733.1 CDS METDI3225 NC_012988.1 3150029 3150658 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 3'-5' exonuclease 3150029..3150658 Methylobacterium extorquens DM4 8192982 YP_003068734.1 CDS METDI3226 NC_012988.1 3150929 3151687 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3150929..3151687 Methylobacterium extorquens DM4 8192983 YP_003068735.1 CDS METDI3227 NC_012988.1 3151684 3152424 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3151684..3152424 Methylobacterium extorquens DM4 8192984 YP_003068736.1 CDS METDI3228 NC_012988.1 3152442 3153311 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17056748, 7876255, 9298646; Product type pt : putative transporter; putative ABC transporter, ATPase 3152442..3153311 Methylobacterium extorquens DM4 8192985 YP_003068737.1 CDS rpoN NC_012988.1 3153875 3155422 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12597275, 1991712; Product type f : factor; sigma N (sigma 54) factor of RNA polymerase 3153875..3155422 Methylobacterium extorquens DM4 8192986 YP_003068738.1 CDS METDI3230 NC_012988.1 3155536 3156144 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1991712, 7876255, 8025669; Product type f : factor; ribosomal subunit interface protein, sigma 54 (RpoN) modulation protein 3155536..3156144 Methylobacterium extorquens DM4 8196050 YP_003068739.1 CDS ptsN NC_012988.1 3156344 3156811 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; sugar-specific enzyme IIA component of PTS 3156344..3156811 Methylobacterium extorquens DM4 8192987 YP_003068740.1 CDS METDI3232 NC_012988.1 3156813 3157142 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3156813..3157142 Methylobacterium extorquens DM4 8195917 YP_003068741.1 CDS bchI NC_012988.1 3157278 3158291 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7892204; Product type pe : putative enzyme; Mg chelatase subunit Bchl, participate to introduce Mg in bacteriochlorophyl with BchH and BchD 3157278..3158291 Methylobacterium extorquens DM4 8192988 YP_003068742.1 CDS gpmA NC_012988.1 3158315 3158953 R catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(3158315..3158953) Methylobacterium extorquens DM4 8195132 YP_003068743.1 CDS dapB NC_012988.1 3159090 3159893 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(3159090..3159893) Methylobacterium extorquens DM4 8195529 YP_003068744.1 CDS METDI3236 NC_012988.1 3159968 3160663 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative multiple antibiotic resistance protein, MarC family transport protein complement(3159968..3160663) Methylobacterium extorquens DM4 8195271 YP_003068745.1 CDS METDI3237 NC_012988.1 3160700 3161452 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3160700..3161452) Methylobacterium extorquens DM4 8192989 YP_003068746.1 CDS METDI3238 NC_012988.1 3161666 3162445 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydroxyacylglutathione hydrolase (gloB-like) with metallo-hydrolase/oxidoreductase domain 3161666..3162445 Methylobacterium extorquens DM4 8192990 YP_003068747.1 CDS METDI3239 NC_012988.1 3162706 3162858 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3162706..3162858 Methylobacterium extorquens DM4 8192991 YP_003068748.1 CDS xerD NC_012988.1 3162855 3163841 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10361305, 10635320, 11832, 20209354, 94006566, 94100681, 94222031, 9632255; Product type e : enzyme; Tyrosine recombinase xerD 3162855..3163841 Methylobacterium extorquens DM4 8192992 YP_003068749.1 CDS METDI3241 NC_012988.1 3164012 3165229 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; diguanylate cyclase precursor with GGDEF motif; putative membrane protein 3164012..3165229 Methylobacterium extorquens DM4 8196338 YP_003068750.1 CDS METDI3242 NC_012988.1 3165363 3167594 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glycoside hydrolase, family 3, N-terminal and C-terminal domain (bglX-like) 3165363..3167594 Methylobacterium extorquens DM4 8192993 YP_003068751.1 CDS yejE NC_012988.1 3167601 3168803 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide transporter subunit ; permease component of ABC superfamily transporter complement(3167601..3168803) Methylobacterium extorquens DM4 8192994 YP_003068752.1 CDS METDI3244 NC_012988.1 3168841 3169365 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3168841..3169365) Methylobacterium extorquens DM4 8196361 YP_003068753.1 CDS METDI3245 NC_012988.1 3169362 3170546 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(3169362..3170546) Methylobacterium extorquens DM4 8192995 YP_003068754.1 CDS METDI3246 NC_012988.1 3170543 3170893 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3170543..3170893) Methylobacterium extorquens DM4 8192996 YP_003068755.1 CDS METDI3247 NC_012988.1 3170984 3171157 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3170984..3171157 Methylobacterium extorquens DM4 8192997 YP_003068756.1 CDS METDI3248 NC_012988.1 3171315 3172703 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12107133, 12107134, 15793131; Product type t : transporter; multidrug efflux protein, subunit A; RND efflux transporter, membrane fusion protein subunit 3171315..3172703 Methylobacterium extorquens DM4 8192998 YP_003068757.1 CDS METDI3249 NC_012988.1 3172716 3175853 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12107133, 12107134; Product type t : transporter; multidrug efflux protein, subunit B; RND efflux transporter 3172716..3175853 Methylobacterium extorquens DM4 8192999 YP_003068758.1 CDS METDI3251 NC_012988.1 3176380 3179694 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12107133, 12107134; Product type t : transporter; multidrug efflux system, subunit C; RND efflux exporter 3176380..3179694 Methylobacterium extorquens DM4 8193000 YP_003068759.1 CDS METDI3252 NC_012988.1 3179768 3181255 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative outer membrane lipoprotein precursor 3179768..3181255 Methylobacterium extorquens DM4 8193001 YP_003068760.1 CDS zwf NC_012988.1 3181356 3182864 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 3181356..3182864 Methylobacterium extorquens DM4 8193002 YP_003068761.1 CDS leuB NC_012988.1 3182975 3184084 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9003442; Product type e : enzyme; 3-isopropylmalate dehydrogenase complement(3182975..3184084) Methylobacterium extorquens DM4 8196383 YP_003068762.1 CDS METDI3255 NC_012988.1 3184192 3184509 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3184192..3184509) Methylobacterium extorquens DM4 8195629 YP_003068763.1 CDS METDI3256 NC_012988.1 3184675 3186291 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3184675..3186291 Methylobacterium extorquens DM4 8193003 YP_003068764.1 CDS METDI3257 NC_012988.1 3186451 3188139 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative decarboxylase, Thiamine pyrophosphate-requiring 3186451..3188139 Methylobacterium extorquens DM4 8193004 YP_003068765.1 CDS METDI3258 NC_012988.1 3188160 3188591 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3188160..3188591 Methylobacterium extorquens DM4 8193005 YP_003068766.1 CDS ispA NC_012988.1 3188769 3189731 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; geranyltranstransferase (farnesyl-diphosphate synthase) complement(3188769..3189731) Methylobacterium extorquens DM4 8193006 YP_003068767.1 CDS mgtA NC_012988.1 3189768 3190553 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8830253; Product type e : enzyme; monofunctional biosynthetic peptidoglycan transglycosylase 3189768..3190553 Methylobacterium extorquens DM4 8195606 YP_003068768.1 CDS phr NC_012988.1 3190558 3191961 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7813451; Product type e : enzyme; deoxyribodipyrimidine photolyase (DNA photolyase) complement(3190558..3191961) Methylobacterium extorquens DM4 8195693 YP_003068769.1 CDS METDI3262 NC_012988.1 3192581 3193702 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative extracellular solute-binding protein family 7, twin-arginine translocation pathway signal complement(3192581..3193702) Methylobacterium extorquens DM4 8195864 YP_003068770.1 CDS METDI3263 NC_012988.1 3193837 3194412 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16926146; hypothetical protein 3193837..3194412 Methylobacterium extorquens DM4 8193007 YP_003068771.1 CDS METDI3264 NC_012988.1 3194422 3195546 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative extracellular ligand-binding receptor precursor complement(3194422..3195546) Methylobacterium extorquens DM4 8193008 YP_003068772.1 CDS METDI3265 NC_012988.1 3195866 3197038 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative capsule polysaccharide export outer membrane protein complement(3195866..3197038) Methylobacterium extorquens DM4 8193009 YP_003068773.1 CDS METDI3266 NC_012988.1 3197236 3198705 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Capsular polysaccharide biosynthesis protein complement(3197236..3198705) Methylobacterium extorquens DM4 8193010 YP_003068774.1 CDS METDI3267 NC_012988.1 3198712 3200661 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3198712..3200661) Methylobacterium extorquens DM4 8193011 YP_003068775.1 CDS METDI3268 NC_012988.1 3201024 3202331 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10094710, 8397187; Product type pm : putative membrane component; putative capsular polysaccharide biosynthesis/export protein, (kpsS, Synonyms : wcbO) 3201024..3202331 Methylobacterium extorquens DM4 8193012 YP_003068776.1 CDS METDI3269 NC_012988.1 3202388 3203155 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, short-chain dehydrogenase/reductase family 3202388..3203155 Methylobacterium extorquens DM4 8193013 YP_003068777.1 CDS METDI3270 NC_012988.1 3203155 3204012 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Methionyl-tRNA formyltransferase (partial) 3203155..3204012 Methylobacterium extorquens DM4 8193014 YP_003068778.1 CDS metY-2 NC_012988.1 3204016 3205296 R catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase complement(3204016..3205296) Methylobacterium extorquens DM4 8193015 YP_003068779.1 CDS petA NC_012988.1 3205856 3206404 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12597275, 2541921; Product type e : enzyme; Ubiquinol-cytochrome c reductase complex, iron-sulfur subunit (Rieske iron-sulfur protein) 3205856..3206404 Methylobacterium extorquens DM4 8195689 YP_003068780.1 CDS petB NC_012988.1 3206439 3207731 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2176897, 2556259; Product type e : enzyme; Ubiquinol-cytochrome c reductase complex, cytochrome b subunit 3206439..3207731 Methylobacterium extorquens DM4 8195845 YP_003068781.1 CDS petC NC_012988.1 3207753 3208646 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10873857, 11880631; Product type e : enzyme; Ubiquinol-cytochrome c reductase complex, cytochrome c1 subunit 3207753..3208646 Methylobacterium extorquens DM4 8195846 YP_003068782.1 CDS METDI3275 NC_012988.1 3208858 3209733 D Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate; 5'-methylthioadenosine phosphorylase 3208858..3209733 Methylobacterium extorquens DM4 8195847 YP_003068783.1 CDS METDI3276 NC_012988.1 3209838 3210098 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3209838..3210098) Methylobacterium extorquens DM4 8193016 YP_003068784.1 CDS METDI3277 NC_012988.1 3210133 3211038 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3210133..3211038) Methylobacterium extorquens DM4 8193017 YP_003068785.1 CDS hisB NC_012988.1 3211249 3211836 D catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 3211249..3211836 Methylobacterium extorquens DM4 8193018 YP_003068786.1 CDS METDI3279 NC_012988.1 3211859 3212362 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3211859..3212362 Methylobacterium extorquens DM4 8195558 YP_003068787.1 CDS hisH NC_012988.1 3212359 3213021 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 3212359..3213021 Methylobacterium extorquens DM4 8193019 YP_003068788.1 CDS hisA NC_012988.1 3213063 3213830 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase 3213063..3213830 Methylobacterium extorquens DM4 8195564 YP_003068789.1 CDS hisF NC_012988.1 3213878 3214654 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 3213878..3214654 Methylobacterium extorquens DM4 8195557 YP_003068790.1 CDS hisE NC_012988.1 3214775 3215098 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2664449; Product type e : enzyme; phosphoribosyl-ATP pyrophosphatase 3214775..3215098 Methylobacterium extorquens DM4 8195562 YP_003068791.1 CDS coaA NC_012988.1 3215095 3216108 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3215095..3216108 Methylobacterium extorquens DM4 8195561 YP_003068792.1 CDS METDI3285 NC_012988.1 3216276 3217610 R Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; methyl-accepting chemotaxis sensory transducer complement(3216276..3217610) Methylobacterium extorquens DM4 8195177 YP_003068793.1 CDS METDI3287 NC_012988.1 3218528 3219673 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3218528..3219673 Methylobacterium extorquens DM4 8193020 YP_003068794.1 CDS METDI3288 NC_012988.1 3219865 3220386 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) 3219865..3220386 Methylobacterium extorquens DM4 8193021 YP_003068795.1 CDS METDI3289 NC_012988.1 3220777 3221004 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3220777..3221004 Methylobacterium extorquens DM4 8193022 YP_003068796.1 CDS METDI3291 NC_012988.1 3221137 3221808 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3221137..3221808 Methylobacterium extorquens DM4 8193023 YP_003068797.1 CDS METDI3292 NC_012988.1 3221929 3222255 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3221929..3222255) Methylobacterium extorquens DM4 8193024 YP_003068798.1 CDS gap20 NC_012988.1 3222463 3222903 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12399487, 16926146; Product type f : factor; Granule-associated 20 kDa protein (phasin) complement(3222463..3222903) Methylobacterium extorquens DM4 8193025 YP_003068799.1 CDS METDI3294 NC_012988.1 3223181 3225709 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase with HK Homodimeric domain, ATPase domain and a sensory PAS domain 3223181..3225709 Methylobacterium extorquens DM4 8195466 YP_003068800.1 CDS acs NC_012988.1 3225969 3227918 D Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 3225969..3227918 Methylobacterium extorquens DM4 8193026 YP_003068801.1 CDS METDI3296 NC_012988.1 3228131 3228517 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14563880; Product type pm : putative membrane component; hypothetical protein 3228131..3228517 Methylobacterium extorquens DM4 8195057 YP_003068802.1 CDS actP NC_012988.1 3228514 3230199 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14563880; Product type t : transporter; Cation/acetate symporter actP; acetate and glycolate permease 3228514..3230199 Methylobacterium extorquens DM4 8193027 YP_003068803.1 CDS METDI3298 NC_012988.1 3230506 3232194 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS transporter membrane protein 3230506..3232194 Methylobacterium extorquens DM4 8195060 YP_003068804.1 CDS purH NC_012988.1 3232408 3234006 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2192230, 2687276; Product type e : enzyme; bifunctional: IMP cyclohydrolase (N-terminal); phosphoribosylaminoimidazolecarboxamide formyltransferase (C-terminal) complement(3232408..3234006) Methylobacterium extorquens DM4 8193028 YP_003068805.1 CDS METDI3300 NC_012988.1 3234230 3235921 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3234230..3235921) Methylobacterium extorquens DM4 8195935 YP_003068806.1 CDS sseA NC_012988.1 3236130 3236978 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11445076; Product type e : enzyme; 3-mercaptopyruvate sulfurtransferase complement(3236130..3236978) Methylobacterium extorquens DM4 8193029 YP_003068807.1 CDS METDI3302 NC_012988.1 3237251 3237487 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3237251..3237487 Methylobacterium extorquens DM4 8196148 YP_003068808.1 CDS METDI3303 NC_012988.1 3237598 3238683 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3237598..3238683) Methylobacterium extorquens DM4 8193030 YP_003068809.1 CDS rhlE NC_012988.1 3239358 3240890 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10361280, 14731278, 15196029, 15554979, 1931833, 94312114; Product type e : enzyme; RNA helicase 3239358..3240890 Methylobacterium extorquens DM4 8193031 YP_003068810.1 CDS METDI3305 NC_012988.1 3241065 3241250 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3241065..3241250 Methylobacterium extorquens DM4 8195989 YP_003068811.1 CDS METDI3306 NC_012988.1 3241377 3241661 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3241377..3241661 Methylobacterium extorquens DM4 8193032 YP_003068812.1 CDS METDI3307 NC_012988.1 3241871 3242014 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3241871..3242014 Methylobacterium extorquens DM4 8193033 YP_003068813.1 CDS yciA NC_012988.1 3242102 3242521 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15808744, 2985285; Product type pe : putative enzyme; acyl-CoA thioester hydrolase 3242102..3242521 Methylobacterium extorquens DM4 8193034 YP_003068814.1 CDS ycbL NC_012988.1 3242687 3243331 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal-binding hydrolase 3242687..3243331 Methylobacterium extorquens DM4 8196357 YP_003068815.1 CDS gyrB NC_012988.1 3243570 3246017 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1656869, 8226640; Product type e : enzyme; DNA gyrase, subunit B (type II topoisomerase) 3243570..3246017 Methylobacterium extorquens DM4 8196354 YP_003068816.1 CDS METDI3311 NC_012988.1 3246081 3246788 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor complement(3246081..3246788) Methylobacterium extorquens DM4 8195544 YP_003068817.1 CDS mscL NC_012988.1 3247215 3247640 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9632260; Product type t : transporter; mechanosensitive channel 3247215..3247640 Methylobacterium extorquens DM4 8193035 YP_003068818.1 CDS METDI3313 NC_012988.1 3247647 3247937 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3247647..3247937) Methylobacterium extorquens DM4 8195725 YP_003068819.1 CDS METDI3314 NC_012988.1 3248229 3248642 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16926146; hypothetical protein complement(3248229..3248642) Methylobacterium extorquens DM4 8193036 YP_003068820.1 CDS METDI3315 NC_012988.1 3248825 3250006 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aspartate transaminase complement(3248825..3250006) Methylobacterium extorquens DM4 8193037 YP_003068821.1 CDS METDI3316 NC_012988.1 3250128 3250319 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3250128..3250319) Methylobacterium extorquens DM4 8193038 YP_003068822.1 CDS METDI3317 NC_012988.1 3250470 3251876 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase complement(3250470..3251876) Methylobacterium extorquens DM4 8193039 YP_003068823.1 CDS ompR NC_012988.1 3251884 3252612 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10464234, 2845093, 2997120, 3010044, 6292199, 91175693, 92165726, 93287101; Product type r : regulator; DNA-binding response regulator in two-component regulatory system with EnvZ complement(3251884..3252612) Methylobacterium extorquens DM4 8193040 YP_003068824.1 CDS METDI3319 NC_012988.1 3252612 3253157 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, MarR family complement(3252612..3253157) Methylobacterium extorquens DM4 8195807 YP_003068825.1 CDS METDI3320 NC_012988.1 3253396 3254283 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 3253396..3254283 Methylobacterium extorquens DM4 8193041 YP_003068826.1 CDS METDI3321 NC_012988.1 3254386 3254649 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3254386..3254649 Methylobacterium extorquens DM4 8193042 YP_003068827.1 CDS METDI3322 NC_012988.1 3255033 3255140 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11359562, 9623911; Product type pf : putative factor; putative PilA2 pilus assembly protein, Flp/Fap pilin component 3255033..3255140 Methylobacterium extorquens DM4 8193043 YP_003068828.1 CDS METDI3323 NC_012988.1 3255290 3256060 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3255290..3256060) Methylobacterium extorquens DM4 8193044 YP_003068829.1 CDS METDI3324 NC_012988.1 3256298 3257779 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3256298..3257779) Methylobacterium extorquens DM4 8193045 YP_003068830.1 CDS kefB NC_012988.1 3257772 3259670 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; potassium:proton antiporter complement(3257772..3259670) Methylobacterium extorquens DM4 8193046 YP_003068831.1 CDS ispH NC_012988.1 3260023 3261045 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3260023..3261045 Methylobacterium extorquens DM4 8195623 YP_003068832.1 CDS thrB NC_012988.1 3261144 3262109 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10589737; Product type e : enzyme; homoserine kinase 3261144..3262109 Methylobacterium extorquens DM4 8195611 YP_003068833.1 CDS METDI3328 NC_012988.1 3262158 3262640 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15188393, 16926146; Product type pe : putative enzyme; putative peroxiredoxin protein, antioxidant protein, AhpC/TSA family protein complement(3262158..3262640) Methylobacterium extorquens DM4 8196193 YP_003068834.1 CDS METDI3329 NC_012988.1 3262764 3263372 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3262764..3263372 Methylobacterium extorquens DM4 8193047 YP_003068835.1 CDS METDI3330 NC_012988.1 3263410 3264471 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3263410..3264471) Methylobacterium extorquens DM4 8193048 YP_003068836.1 CDS alaS NC_012988.1 3264655 3267330 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(3264655..3267330) Methylobacterium extorquens DM4 8193049 YP_003068837.1 CDS METDI3332 NC_012988.1 3267425 3268132 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3267425..3268132) Methylobacterium extorquens DM4 8195067 YP_003068838.1 CDS METDI3333 NC_012988.1 3268207 3268809 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase 3268207..3268809 Methylobacterium extorquens DM4 8193050 YP_003068839.1 CDS recA NC_012988.1 3268891 3269991 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; DNA strand exchange and recombination protein with protease and nuclease activity complement(3268891..3269991) Methylobacterium extorquens DM4 8193051 YP_003068840.1 CDS cckA NC_012988.1 3270246 3272957 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10199407; Product type r : regulator; sensor hybrid histidine kinase with multiple PAS and response regulator receiver domains complement(3270246..3272957) Methylobacterium extorquens DM4 8195967 YP_003068841.1 CDS flhB NC_012988.1 3273116 3274180 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; flagellar biosynthetic protein flhB complement(3273116..3274180) Methylobacterium extorquens DM4 8195151 YP_003068842.1 CDS fliR NC_012988.1 3274283 3275059 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; flagellar biosynthetic protein FliR complement(3274283..3275059) Methylobacterium extorquens DM4 8195412 YP_003068843.1 CDS fliQ NC_012988.1 3275105 3275371 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; flagellar biosynthesis complement(3275105..3275371) Methylobacterium extorquens DM4 8195430 YP_003068844.1 CDS fliE NC_012988.1 3275453 3275776 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; Flagellar hook-basal body complex protein FliE complement(3275453..3275776) Methylobacterium extorquens DM4 8195428 YP_003068845.1 CDS flgC NC_012988.1 3275782 3276192 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(3275782..3276192) Methylobacterium extorquens DM4 8195414 YP_003068846.1 CDS flgB NC_012988.1 3276227 3276643 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar basal body rod protein FlgB complement(3276227..3276643) Methylobacterium extorquens DM4 8195394 YP_003068847.1 CDS METDI3342 NC_012988.1 3276975 3278186 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3276975..3278186 Methylobacterium extorquens DM4 8195392 YP_003068848.1 CDS METDI3343 NC_012988.1 3278294 3279388 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Oxidoreductase, FAD-binding family protein 3278294..3279388 Methylobacterium extorquens DM4 8193052 YP_003068849.1 CDS METDI3344 NC_012988.1 3279391 3280230 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3279391..3280230) Methylobacterium extorquens DM4 8193053 YP_003068850.1 CDS ccmC NC_012988.1 3280428 3281234 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10339610, 12196152, 14532274, 1850420, 7635817; Product type t : transporter; heme exporter protein, cytochrome c-type biogenesis protein; ABC transporter, permease 3280428..3281234 Methylobacterium extorquens DM4 8193054 YP_003068851.1 CDS ccmD NC_012988.1 3281372 3281524 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1850420, 8021193; Product type pm : putative membrane component; heme exporter protein D (cytochrome c-type biogenesis protein cycX) 3281372..3281524 Methylobacterium extorquens DM4 8195154 YP_003068852.1 CDS ccmG NC_012988.1 3281521 3282141 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11256948, 12196152, 9716493; Product type e : enzyme; Periplasmic protein thiol:disulfide oxidoreductase, cytochrome c-type biogenesis 3281521..3282141 Methylobacterium extorquens DM4 8195155 YP_003068853.1 CDS METDI3348 NC_012988.1 3282264 3283007 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Fe-S oxidoreductase 3282264..3283007 Methylobacterium extorquens DM4 8195156 YP_003068854.1 CDS METDI3349 NC_012988.1 3283004 3284578 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, putative 4Fe-4S ferredoxin domain 3283004..3284578 Methylobacterium extorquens DM4 8193055 YP_003068855.1 CDS METDI3350 NC_012988.1 3284536 3285180 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3284536..3285180 Methylobacterium extorquens DM4 8193056 YP_003068856.1 CDS METDI3351 NC_012988.1 3285268 3286128 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3285268..3286128 Methylobacterium extorquens DM4 8193057 YP_003068857.1 CDS rplM NC_012988.1 3286543 3287004 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3286543..3287004 Methylobacterium extorquens DM4 8193058 YP_003068858.1 CDS rpsI NC_012988.1 3287001 3287492 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3287001..3287492 Methylobacterium extorquens DM4 8196022 YP_003068859.1 CDS METDI3354 NC_012988.1 3287575 3287949 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3287575..3287949 Methylobacterium extorquens DM4 8196060 YP_003068860.1 CDS METDI3355 NC_012988.1 3288031 3288240 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; molybdenum-pterin binding protein 3288031..3288240 Methylobacterium extorquens DM4 8193059 YP_003068861.1 CDS METDI3356 NC_012988.1 3288253 3289131 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3288253..3289131) Methylobacterium extorquens DM4 8193060 YP_003068862.1 CDS METDI3357 NC_012988.1 3289194 3290984 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused ATPase and transmembrane permease domains complement(3289194..3290984) Methylobacterium extorquens DM4 8193061 YP_003068863.1 CDS METDI3358 NC_012988.1 3291145 3291315 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3291145..3291315 Methylobacterium extorquens DM4 8193062 YP_003068864.1 CDS METDI3359 NC_012988.1 3291364 3291837 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3291364..3291837 Methylobacterium extorquens DM4 8193063 YP_003068865.1 CDS METDI3360 NC_012988.1 3292752 3293108 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3292752..3293108 Methylobacterium extorquens DM4 8193064 YP_003068866.1 CDS METDI3362 NC_012988.1 3293683 3293901 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3293683..3293901) Methylobacterium extorquens DM4 8196225 YP_003068867.1 CDS METDI3363 NC_012988.1 3293898 3294569 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative septum formation protein, Maf-like protein complement(3293898..3294569) Methylobacterium extorquens DM4 8193066 YP_003068868.1 CDS METDI3364 NC_012988.1 3294853 3295224 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3294853..3295224) Methylobacterium extorquens DM4 8196265 YP_003068869.1 CDS METDI3365 NC_012988.1 3295125 3295430 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3295125..3295430) Methylobacterium extorquens DM4 8193068 YP_003068870.1 CDS METDI3366 NC_012988.1 3295484 3295834 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3295484..3295834) Methylobacterium extorquens DM4 8193069 YP_003068871.1 CDS METDI3367 NC_012988.1 3296078 3297106 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3296078..3297106 Methylobacterium extorquens DM4 8193070 YP_003068872.1 CDS METDI3368 NC_012988.1 3297117 3297479 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3297117..3297479 Methylobacterium extorquens DM4 8193071 YP_003068873.1 CDS METDI3369 NC_012988.1 3298399 3299307 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3298399..3299307 Methylobacterium extorquens DM4 8193072 YP_003068874.1 CDS METDI3371 NC_012988.1 3299550 3299771 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3299550..3299771) Methylobacterium extorquens DM4 8193073 YP_003068875.1 CDS METDI3372 NC_012988.1 3300067 3300687 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3300067..3300687) Methylobacterium extorquens DM4 8193074 YP_003068876.1 CDS METDI3373 NC_012988.1 3300684 3300884 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3300684..3300884) Methylobacterium extorquens DM4 8193075 YP_003068877.1 CDS METDI3374 NC_012988.1 3300892 3301413 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3300892..3301413) Methylobacterium extorquens DM4 8193076 YP_003068878.1 CDS METDI3376 NC_012988.1 3301604 3301885 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3301604..3301885) Methylobacterium extorquens DM4 8193078 YP_003068879.1 CDS METDI3377 NC_012988.1 3301882 3302784 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3301882..3302784) Methylobacterium extorquens DM4 8193079 YP_003068880.1 CDS METDI3378 NC_012988.1 3302909 3303178 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3302909..3303178 Methylobacterium extorquens DM4 8193080 YP_003068881.1 CDS METDI3379 NC_012988.1 3303390 3304355 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative integrase 3303390..3304355 Methylobacterium extorquens DM4 8193081 YP_003068882.1 CDS METDI3380 NC_012988.1 3304496 3304675 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3304496..3304675) Methylobacterium extorquens DM4 8193082 YP_003068883.1 CDS METDI3382 NC_012988.1 3306692 3307996 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative integrase complement(3306692..3307996) Methylobacterium extorquens DM4 8193084 YP_003068884.1 CDS METDI3383 NC_012988.1 3307927 3308142 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3307927..3308142) Methylobacterium extorquens DM4 8193085 YP_003068885.1 CDS METDI3384 NC_012988.1 3308355 3308585 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3308355..3308585) Methylobacterium extorquens DM4 8193086 YP_003068886.1 CDS METDI3385 NC_012988.1 3308863 3309153 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3308863..3309153) Methylobacterium extorquens DM4 8193087 YP_003068887.1 CDS METDI3386 NC_012988.1 3309318 3311561 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent siderophore receptor complement(3309318..3311561) Methylobacterium extorquens DM4 8193088 YP_003068888.1 CDS METDI3387 NC_012988.1 3312246 3312377 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3312246..3312377 Methylobacterium extorquens DM4 8195030 YP_003068889.1 CDS METDI3388 NC_012988.1 3312495 3312890 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3312495..3312890 Methylobacterium extorquens DM4 8193090 YP_003068890.1 CDS METDI3389 NC_012988.1 3313021 3313284 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3313021..3313284 Methylobacterium extorquens DM4 8193091 YP_003068891.1 CDS ccmB NC_012988.1 3313328 3313993 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; heme exporter subunit ; membrane component of ABC superfamily complement(3313328..3313993) Methylobacterium extorquens DM4 8193092 YP_003068892.1 CDS ccmA NC_012988.1 3313993 3314814 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10339610, 12196152, 1850420, 7635817; Product type t : transporter; heme export protein, cytochrome C-type biogenesis ccmA complement(3313993..3314814) Methylobacterium extorquens DM4 8195153 YP_003068893.1 CDS METDI3392 NC_012988.1 3314858 3315055 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3314858..3315055 Methylobacterium extorquens DM4 8195152 YP_003068894.1 CDS acnA NC_012988.1 3315362 3318061 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10585860; Product type e : enzyme; aconitate hydratase 3315362..3318061 Methylobacterium extorquens DM4 8193093 YP_003068895.1 CDS METDI3394 NC_012988.1 3318114 3318548 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3318114..3318548 Methylobacterium extorquens DM4 8195049 YP_003068896.1 CDS METDI3395 NC_012988.1 3318657 3318956 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Antibiotic biosynthesis monooxygenase 3318657..3318956 Methylobacterium extorquens DM4 8193094 YP_003068897.1 CDS maiA NC_012988.1 3319082 3319729 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11327815, 9396740, 9417084, 9925947; Product type e : enzyme; maleylacetoacetate isomerase (glutathione S-transferase) 3319082..3319729 Methylobacterium extorquens DM4 8193095 YP_003068898.1 CDS ndh NC_012988.1 3319886 3321217 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; respiratory NADH dehydrogenase 2; cupric reductase 3319886..3321217 Methylobacterium extorquens DM4 8195659 YP_003068899.1 CDS METDI3398 NC_012988.1 3321303 3321629 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21528828; Product type pe : putative enzyme; putative Ethyl tert-butyl ether degradation EthD 3321303..3321629 Methylobacterium extorquens DM4 8195773 YP_003068900.1 CDS METDI3399 NC_012988.1 3321629 3321940 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3321629..3321940 Methylobacterium extorquens DM4 8193096 YP_003068901.1 CDS METDI3400 NC_012988.1 3322021 3323394 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3322021..3323394) Methylobacterium extorquens DM4 8193097 YP_003068902.1 CDS METDI3401 NC_012988.1 3323803 3324846 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative quinolinate synthetase A (nadA-like) 3323803..3324846 Methylobacterium extorquens DM4 8193098 YP_003068903.1 CDS METDI3402 NC_012988.1 3324846 3326375 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative L-aspartate oxidase (nadB-like) 3324846..3326375 Methylobacterium extorquens DM4 8193099 YP_003068904.1 CDS nadC NC_012988.1 3326368 3327228 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9862811; Product type e : enzyme; nicotinate-mononucleotide pyrophosphorylase 3326368..3327228 Methylobacterium extorquens DM4 8193100 YP_003068905.1 CDS METDI3404 NC_012988.1 3327544 3328212 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3327544..3328212 Methylobacterium extorquens DM4 8195767 YP_003068906.1 CDS METDI3406 NC_012988.1 3328603 3328845 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3328603..3328845 Methylobacterium extorquens DM4 8193101 YP_003068907.1 CDS METDI3407 NC_012988.1 3328992 3329162 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3328992..3329162) Methylobacterium extorquens DM4 8193102 YP_003068908.1 CDS METDI3408 NC_012988.1 3329185 3329613 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3329185..3329613) Methylobacterium extorquens DM4 8193103 YP_003068909.1 CDS moaA NC_012988.1 3329756 3330790 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; molybdenum biosynthetic protein A 3329756..3330790 Methylobacterium extorquens DM4 8193104 YP_003068910.1 CDS METDI3410 NC_012988.1 3330797 3331717 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3330797..3331717) Methylobacterium extorquens DM4 8195702 YP_003068911.1 CDS METDI3411 NC_012988.1 3331618 3332814 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3331618..3332814) Methylobacterium extorquens DM4 8193105 YP_003068912.1 CDS METDI3412 NC_012988.1 3333010 3333876 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 2-hydroxy-3-oxopropionate reductase 3333010..3333876 Methylobacterium extorquens DM4 8193106 YP_003068913.1 CDS miaA NC_012988.1 3333854 3334807 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(3333854..3334807) Methylobacterium extorquens DM4 8193107 YP_003068914.1 CDS METDI3414 NC_012988.1 3334819 3335715 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphoserine phosphatase (serB-like) 3334819..3335715 Methylobacterium extorquens DM4 8195694 YP_003068915.1 CDS METDI3415 NC_012988.1 3335824 3337359 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative serine protease precursor complement(3335824..3337359) Methylobacterium extorquens DM4 8193108 YP_003068916.1 CDS hflC NC_012988.1 3337471 3338412 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor complement(3337471..3338412) Methylobacterium extorquens DM4 8193109 YP_003068917.1 CDS hflK NC_012988.1 3338409 3339557 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; protease subunit hflK complement(3338409..3339557) Methylobacterium extorquens DM4 8195554 YP_003068918.1 CDS dfrA NC_012988.1 3339849 3340349 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; dihydrofolate reductase complement(3339849..3340349) Methylobacterium extorquens DM4 8195555 YP_003068919.1 CDS thyA NC_012988.1 3340349 3341143 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; thymidylate synthetase complement(3340349..3341143) Methylobacterium extorquens DM4 8195292 YP_003068920.1 CDS METDI3420 NC_012988.1 3341231 3342100 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3341231..3342100) Methylobacterium extorquens DM4 8196196 YP_003068921.1 CDS METDI3421 NC_012988.1 3342527 3343180 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3342527..3343180 Methylobacterium extorquens DM4 8193110 YP_003068922.1 CDS METDI3422 NC_012988.1 3343231 3344631 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cytochrome P450 hydroxylase superfamily proteins complement(3343231..3344631) Methylobacterium extorquens DM4 8193111 YP_003068923.1 CDS fumC NC_012988.1 3344757 3346175 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; fumarase C 3344757..3346175 Methylobacterium extorquens DM4 8193112 YP_003068924.1 CDS METDI3424 NC_012988.1 3346236 3346424 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3346236..3346424 Methylobacterium extorquens DM4 8195460 YP_003068925.1 CDS METDI3425 NC_012988.1 3346421 3346732 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3346421..3346732 Methylobacterium extorquens DM4 8193113 YP_003068926.1 CDS METDI3426 NC_012988.1 3346655 3347140 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3346655..3347140) Methylobacterium extorquens DM4 8193114 YP_003068927.1 CDS METDI3427 NC_012988.1 3347210 3348004 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3347210..3348004) Methylobacterium extorquens DM4 8193115 YP_003068928.1 CDS METDI3428 NC_012988.1 3348011 3348532 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative DedA family protein complement(3348011..3348532) Methylobacterium extorquens DM4 8193116 YP_003068929.1 CDS pdxY NC_012988.1 3348751 3349602 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 3348751..3349602 Methylobacterium extorquens DM4 8193117 YP_003068930.1 CDS METDI3430 NC_012988.1 3349619 3350551 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15449932, 15545603; Product type e : enzyme; Phenazine biosynthesis PhzC/PhzF-like protein 3349619..3350551 Methylobacterium extorquens DM4 8195843 YP_003068931.1 CDS METDI3431 NC_012988.1 3350541 3351272 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3350541..3351272 Methylobacterium extorquens DM4 8193118 YP_003068932.1 CDS METDI3432 NC_012988.1 3351284 3351610 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3351284..3351610) Methylobacterium extorquens DM4 8193119 YP_003068933.1 CDS leuA NC_012988.1 3352034 3353596 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 3352034..3353596 Methylobacterium extorquens DM4 8193120 YP_003068934.1 CDS ilvD NC_012988.1 3353789 3355624 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; dihydroxyacid dehydratase 3353789..3355624 Methylobacterium extorquens DM4 8195628 YP_003068935.1 CDS METDI3435 NC_012988.1 3355913 3356923 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3355913..3356923 Methylobacterium extorquens DM4 8195594 YP_003068936.1 CDS ycjG NC_012988.1 3356937 3357917 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11747448; Product type e : enzyme; L-Ala-D/L-Glu epimerase 3356937..3357917 Methylobacterium extorquens DM4 8193121 YP_003068937.1 CDS METDI3437 NC_012988.1 3357927 3359045 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3357927..3359045) Methylobacterium extorquens DM4 8196358 YP_003068938.1 CDS METDI3438 NC_012988.1 3359361 3360554 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; inositol-3-phosphate synthase 3359361..3360554 Methylobacterium extorquens DM4 8193122 YP_003068939.1 CDS METDI3439 NC_012988.1 3360609 3361487 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3360609..3361487 Methylobacterium extorquens DM4 8193123 YP_003068940.1 CDS METDI3440 NC_012988.1 3361519 3362700 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3361519..3362700 Methylobacterium extorquens DM4 8193124 YP_003068941.1 CDS METDI3441 NC_012988.1 3362700 3363728 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 3362700..3363728 Methylobacterium extorquens DM4 8193125 YP_003068942.1 CDS METDI3442 NC_012988.1 3363921 3365540 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3363921..3365540 Methylobacterium extorquens DM4 8193126 YP_003068943.1 CDS METDI3443 NC_012988.1 3365537 3366430 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10913097, 14996803; Product type pe : putative enzyme; putative glycosyl isomerase/epimerase 3365537..3366430 Methylobacterium extorquens DM4 8193127 YP_003068944.1 CDS METDI3444 NC_012988.1 3366427 3367665 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10048024, 8631780; Product type pe : putative enzyme; putative glycosyl transferase 3366427..3367665 Methylobacterium extorquens DM4 8193128 YP_003068945.1 CDS METDI3445 NC_012988.1 3367662 3368423 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10094699, 10099135; hypothetical protein 3367662..3368423 Methylobacterium extorquens DM4 8193129 YP_003068946.1 CDS METDI3446 NC_012988.1 3368407 3369033 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3368407..3369033 Methylobacterium extorquens DM4 8193130 YP_003068947.1 CDS METDI3447 NC_012988.1 3369245 3370276 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3369245..3370276 Methylobacterium extorquens DM4 8193131 YP_003068948.1 CDS METDI3448 NC_012988.1 3370300 3371589 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; PhoR-like sensor histidine kinase 3370300..3371589 Methylobacterium extorquens DM4 8193132 YP_003068949.1 CDS METDI3449 NC_012988.1 3371790 3374288 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; copper-transporting P-type ATPase 3371790..3374288 Methylobacterium extorquens DM4 8193133 YP_003068950.1 CDS METDI3450 NC_012988.1 3374285 3374749 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11936079, 12213931; Product type r : regulator; heavy metal-dependent transcription regulator HmrR, putative copper efflux regulator CueR, MerR family 3374285..3374749 Methylobacterium extorquens DM4 8193134 YP_003068951.1 CDS METDI3451 NC_012988.1 3374837 3376003 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; amidohydrolase 3374837..3376003 Methylobacterium extorquens DM4 8193135 YP_003068952.1 CDS METDI3453 NC_012988.1 3376454 3377443 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase; membrane protein complement(3376454..3377443) Methylobacterium extorquens DM4 8193136 YP_003068953.1 CDS truB NC_012988.1 3378471 3379496 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12427942, 96079944; Product type e : enzyme; tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase) complement(3378471..3379496) Methylobacterium extorquens DM4 8193138 YP_003068954.1 CDS rbfA NC_012988.1 3379705 3380142 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7535280, 9422595; Product type s : structure; ribosome-binding factor A complement(3379705..3380142) Methylobacterium extorquens DM4 8196281 YP_003068955.1 CDS infB NC_012988.1 3380245 3383214 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14532131, 14691238, 1764105, 18059, 92075771, 1805969, 92260539, 99355440; Product type f : factor; Translation initiation factor IF-2 complement(3380245..3383214) Methylobacterium extorquens DM4 8195965 YP_003068956.1 CDS METDI3460 NC_012988.1 3383279 3384031 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3383279..3384031) Methylobacterium extorquens DM4 8195598 YP_003068957.1 CDS nusA NC_012988.1 3384064 3385701 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; transcription termination/antitermination L factor complement(3384064..3385701) Methylobacterium extorquens DM4 8193139 YP_003068958.1 CDS METDI3462 NC_012988.1 3385815 3386570 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3385815..3386570) Methylobacterium extorquens DM4 8195801 YP_003068959.1 CDS vatD NC_012988.1 3386855 3387508 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Streptogramin A acetyltransferase (Virginiamycin acetyltransferase D) 3386855..3387508 Methylobacterium extorquens DM4 8193140 YP_003068960.1 CDS METDI3464 NC_012988.1 3387445 3387621 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3387445..3387621) Methylobacterium extorquens DM4 8196334 YP_003068961.1 CDS asdB NC_012988.1 3387836 3388870 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9163523; Product type e : enzyme; aspartate-semialdehyde dehydrogenase complement(3387836..3388870) Methylobacterium extorquens DM4 8193141 YP_003068962.1 CDS METDI3466 NC_012988.1 3389204 3390085 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3389204..3390085 Methylobacterium extorquens DM4 8195108 YP_003068963.1 CDS METDI3467 NC_012988.1 3390199 3390612 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3390199..3390612 Methylobacterium extorquens DM4 8193142 YP_003068964.1 CDS speG NC_012988.1 3390676 3391224 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077207; Product type e : enzyme; spermidine N1-acetyltransferase complement(3390676..3391224) Methylobacterium extorquens DM4 8193143 YP_003068965.1 CDS METDI3469 NC_012988.1 3391308 3391601 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3391308..3391601) Methylobacterium extorquens DM4 8196142 YP_003068966.1 CDS METDI3470 NC_012988.1 3391720 3392940 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14556637, 2013568, 7765511; Product type pr : putative regulator; putative regulatory protein (nitrile hydratase activator like), putative GTPase, putative cobalamin biosynthesis protein (CobW homolog) complement(3391720..3392940) Methylobacterium extorquens DM4 8193144 YP_003068967.1 CDS METDI3471 NC_012988.1 3393166 3393792 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type r : regulator; putative transcriptional regulator, TetR family 3393166..3393792 Methylobacterium extorquens DM4 8193145 YP_003068968.1 CDS METDI3472 NC_012988.1 3393958 3394437 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3393958..3394437 Methylobacterium extorquens DM4 8193146 YP_003068969.1 CDS METDI3473 NC_012988.1 3394691 3396496 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11055902; Product type pe : putative enzyme; putative malto-oligosyltrehalose trehalohydrolase 3394691..3396496 Methylobacterium extorquens DM4 8193147 YP_003068970.1 CDS METDI3474 NC_012988.1 3396508 3401433 D amylomaltase; acts to release glucose from maltodextrins; putative bifunctional 4-alpha-glucanotransferase/malto-oligosyltrehalose synthase 3396508..3401433 Methylobacterium extorquens DM4 8193148 YP_003068971.1 CDS METDI3475 NC_012988.1 3401572 3404946 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10542168; Product type pe : putative enzyme; putative glycosyl hydrolase, catalytic domain 3401572..3404946 Methylobacterium extorquens DM4 8193149 YP_003068972.1 CDS METDI3478 NC_012988.1 3406398 3407630 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10572129, 15727835; Product type e : enzyme; MiaB-like tRNA modifying enzyme, putative 2-methylthioadenine synthetase complement(3406398..3407630) Methylobacterium extorquens DM4 8193152 YP_003068973.1 CDS dapF NC_012988.1 3407627 3408484 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3031013; Product type e : enzyme; diaminopimelate epimerase complement(3407627..3408484) Methylobacterium extorquens DM4 8193153 YP_003068974.1 CDS METDI3480 NC_012988.1 3408714 3409475 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3408714..3409475 Methylobacterium extorquens DM4 8195274 YP_003068975.1 CDS METDI3481 NC_012988.1 3409525 3410289 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3409525..3410289 Methylobacterium extorquens DM4 8193154 YP_003068976.1 CDS METDI3482 NC_012988.1 3410145 3410333 D Evidence 6 : Doubtful CDS; hypothetical protein 3410145..3410333 Methylobacterium extorquens DM4 8193155 YP_003068977.1 CDS METDI3483 NC_012988.1 3410321 3411436 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative photolyase complement(3410321..3411436) Methylobacterium extorquens DM4 8193156 YP_003068978.1 CDS METDI3484 NC_012988.1 3411541 3411813 D Evidence 6 : Doubtful CDS; hypothetical protein 3411541..3411813 Methylobacterium extorquens DM4 8193157 YP_003068979.1 CDS METDI3485 NC_012988.1 3411908 3412237 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3411908..3412237 Methylobacterium extorquens DM4 8193158 YP_003068980.1 CDS glgB NC_012988.1 3412259 3414613 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 1,4-alpha-glucan branching enzyme complement(3412259..3414613) Methylobacterium extorquens DM4 8193159 YP_003068981.1 CDS METDI3487 NC_012988.1 3414676 3417108 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16052332; Product type pe : putative enzyme; putative trehalose synthase complement(3414676..3417108) Methylobacterium extorquens DM4 8195489 YP_003068982.1 CDS METDI3488 NC_012988.1 3416997 3417404 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3416997..3417404) Methylobacterium extorquens DM4 8193160 YP_003068983.1 CDS ftsY NC_012988.1 3417496 3418962 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15060054, 20026843, 20141178, 88121727, 90279500, 92357006, 99326417; Product type f : factor; fused Signal Recognition Particle (SRP) receptor: membrane binding protein 3417496..3418962 Methylobacterium extorquens DM4 8193161 YP_003068984.1 CDS METDI3490 NC_012988.1 3419002 3419622 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15919996; Product type pm : putative membrane component; putative intracellular septation protein (IspA/IspZ family) 3419002..3419622 Methylobacterium extorquens DM4 8195456 YP_003068985.1 CDS crtC NC_012988.1 3419629 3420528 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; hydroxyneurosporene synthase CrtC complement(3419629..3420528) Methylobacterium extorquens DM4 8193162 YP_003068986.1 CDS METDI3492 NC_012988.1 3420525 3422024 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1612412, 2144293, 2747617, 7721699; Product type e : enzyme; FAD-dependent oxidoreductase precursor, putative phytoene dehydrogenase precursor complement(3420525..3422024) Methylobacterium extorquens DM4 8195217 YP_003068987.1 CDS crtE NC_012988.1 3422130 3422996 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; geranylgeranyl pyrophosphate synthase 3422130..3422996 Methylobacterium extorquens DM4 8193163 YP_003068988.1 CDS crtF NC_012988.1 3423018 3424163 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; hydroxyneurosporene methyltransferase CrtF 3423018..3424163 Methylobacterium extorquens DM4 8195218 YP_003068989.1 CDS bchC NC_012988.1 3424265 3425203 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase 3424265..3425203 Methylobacterium extorquens DM4 8195219 YP_003068990.1 CDS bchX NC_012988.1 3425200 3426204 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; bacteriochlorophyllide reductase iron protein subunit BchX 3425200..3426204 Methylobacterium extorquens DM4 8195126 YP_003068991.1 CDS bchY NC_012988.1 3426208 3427734 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; bacteriochlorophyllide reductase subunit BchY 3426208..3427734 Methylobacterium extorquens DM4 8195137 YP_003068992.1 CDS bchZ NC_012988.1 3427734 3429200 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; bacteriochlorophyllide reductase subunit 3427734..3429200 Methylobacterium extorquens DM4 8195138 YP_003068993.1 CDS METDI3499 NC_012988.1 3429296 3429505 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3429296..3429505 Methylobacterium extorquens DM4 8195139 YP_003068994.1 CDS pufB NC_012988.1 3429674 3429904 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; light-harvesting complex 1 beta chain 3429674..3429904 Methylobacterium extorquens DM4 8193164 YP_003068995.1 CDS pufA NC_012988.1 3429916 3430104 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; light-harvesting complex 1 alpha chain 3429916..3430104 Methylobacterium extorquens DM4 8195924 YP_003068996.1 CDS pufL NC_012988.1 3430180 3431004 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; photosynthetic reaction center subunit L 3430180..3431004 Methylobacterium extorquens DM4 8195923 YP_003068997.1 CDS pufM NC_012988.1 3431127 3432104 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; photosynthetic reaction center subunit M 3431127..3432104 Methylobacterium extorquens DM4 8195926 YP_003068998.1 CDS pufC NC_012988.1 3432101 3433210 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; photosynthetic reaction center cytochrome c subunit-related 3432101..3433210 Methylobacterium extorquens DM4 8195927 YP_003068999.1 CDS METDI3505 NC_012988.1 3433608 3435356 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative type I secretion system ATPase 3433608..3435356 Methylobacterium extorquens DM4 8195925 YP_003069000.1 CDS METDI3506 NC_012988.1 3435356 3436702 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative type I secretion membrane fusion protein, HlyD family 3435356..3436702 Methylobacterium extorquens DM4 8193165 YP_003069001.1 CDS rpmJ NC_012988.1 3436855 3436980 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 3436855..3436980 Methylobacterium extorquens DM4 8193166 YP_003069002.1 CDS METDI3508 NC_012988.1 3437058 3437666 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative tetratrico peptide repeat (TPR) protein precursor 3437058..3437666 Methylobacterium extorquens DM4 8196043 YP_003069003.1 CDS METDI3509 NC_012988.1 3437677 3438672 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9244287; Product type pe : putative enzyme; putative alpha/beta hydrolase, putative haloalkane dehalogenase 3437677..3438672 Methylobacterium extorquens DM4 8193167 YP_003069004.1 CDS pyk NC_012988.1 3438724 3440160 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Pyruvate kinase complement(3438724..3440160) Methylobacterium extorquens DM4 8193168 YP_003069005.1 CDS METDI3511 NC_012988.1 3440528 3441385 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane protein 3440528..3441385 Methylobacterium extorquens DM4 8195945 YP_003069006.1 CDS METDI3512 NC_012988.1 3441713 3442168 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3441713..3442168) Methylobacterium extorquens DM4 8193169 YP_003069007.1 CDS gck NC_012988.1 3442221 3443534 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 9244287; Product type e : enzyme; glycerate kinase complement(3442221..3443534) Methylobacterium extorquens DM4 8193170 YP_003069008.1 CDS METDI3514 NC_012988.1 3443762 3444535 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3443762..3444535 Methylobacterium extorquens DM4 8195473 YP_003069009.1 CDS METDI3515 NC_012988.1 3444594 3444914 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3444594..3444914 Methylobacterium extorquens DM4 8193171 YP_003069010.1 CDS METDI3516 NC_012988.1 3445019 3445285 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3445019..3445285 Methylobacterium extorquens DM4 8193172 YP_003069011.1 CDS METDI3517 NC_012988.1 3445510 3447000 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3445510..3447000) Methylobacterium extorquens DM4 8193173 YP_003069012.1 CDS METDI3518 NC_012988.1 3447236 3449176 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3447236..3449176) Methylobacterium extorquens DM4 8193174 YP_003069013.1 CDS METDI3519 NC_012988.1 3449423 3450913 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11064198, 11158352, 2520824, 9287006; Product type r : regulator; two-component sigma-54 specific transcriptional regulator, Fis subfamily; with N-terminal response receiver, GAF and putative ATPase domains complement(3449423..3450913) Methylobacterium extorquens DM4 8193175 YP_003069014.1 CDS METDI3520 NC_012988.1 3451242 3453119 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9209029; Product type pe : putative enzyme; putative oligoendopeptidase F 3451242..3453119 Methylobacterium extorquens DM4 8193176 YP_003069015.1 CDS METDI3521 NC_012988.1 3453195 3453419 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3453195..3453419 Methylobacterium extorquens DM4 8193177 YP_003069016.1 CDS doc NC_012988.1 3453416 3453802 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12749835, 8411153, 9157244; Product type h : extrachromosomal origin; Death-on-curing family protein 3453416..3453802 Methylobacterium extorquens DM4 8193178 YP_003069017.1 CDS METDI3523 NC_012988.1 3453895 3455265 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3453895..3455265 Methylobacterium extorquens DM4 8195313 YP_003069018.1 CDS METDI3524 NC_012988.1 3455378 3455671 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3455378..3455671 Methylobacterium extorquens DM4 8193179 YP_003069019.1 CDS pntAA NC_012988.1 3455783 3456922 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15188393, 16926146, 8075801; Product type e : enzyme; NAD(P)+ transhydrogenase, subunit alpha part 1 3455783..3456922 Methylobacterium extorquens DM4 8193180 YP_003069020.1 CDS pntAB NC_012988.1 3456944 3457396 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NAD(P) transhydrogenase, subunit alpha part 2 3456944..3457396 Methylobacterium extorquens DM4 8195871 YP_003069021.1 CDS pntB NC_012988.1 3457401 3458801 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11004437, 11250201; Product type e : enzyme; NAD(P) transhydrogenase, subunit beta 3457401..3458801 Methylobacterium extorquens DM4 8195872 YP_003069022.1 CDS recJ NC_012988.1 3458896 3460731 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498723, 10784047, 11085266, 12923078, 1987126, 264988; Product type pe : putative enzyme; putative single-strand DNA-specific exonuclease RecJ 3458896..3460731 Methylobacterium extorquens DM4 8195873 YP_003069023.1 CDS METDI3529 NC_012988.1 3461189 3461923 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family 3461189..3461923 Methylobacterium extorquens DM4 8196271 YP_003069024.1 CDS METDI3530 NC_012988.1 3461975 3462679 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative signal transduction histidine kinase of the HWE family 3461975..3462679 Methylobacterium extorquens DM4 8193181 YP_003069025.1 CDS METDI3531 NC_012988.1 3462883 3464868 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3462883..3464868 Methylobacterium extorquens DM4 8193182 YP_003069026.1 CDS METDI3532 NC_012988.1 3464953 3469260 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3464953..3469260 Methylobacterium extorquens DM4 8193183 YP_003069027.1 CDS METDI3533 NC_012988.1 3469730 3469990 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3469730..3469990 Methylobacterium extorquens DM4 8193184 YP_003069028.1 CDS METDI3534 NC_012988.1 3470183 3470452 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3470183..3470452 Methylobacterium extorquens DM4 8193185 YP_003069029.1 CDS cynS NC_012988.1 3470554 3471042 R catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase complement(3470554..3471042) Methylobacterium extorquens DM4 8193186 YP_003069030.1 CDS METDI3537 NC_012988.1 3471331 3473220 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2792368, 3313281, 3357773; Product type pr : putative regulator; putative sigma-54 specific transcriptional regulator, Fis subfamily; ATPase and PAS domains 3471331..3473220 Methylobacterium extorquens DM4 8195241 YP_003069031.1 CDS METDI3538 NC_012988.1 3473383 3474909 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3473383..3474909 Methylobacterium extorquens DM4 8193187 YP_003069032.1 CDS METDI3539 NC_012988.1 3474934 3475992 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8021187; Product type pe : putative enzyme; putative di-haem cytochrome c peroxidase complement(3474934..3475992) Methylobacterium extorquens DM4 8193188 YP_003069033.1 CDS METDI3540 NC_012988.1 3476162 3476473 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3476162..3476473) Methylobacterium extorquens DM4 8193189 YP_003069034.1 CDS METDI3541 NC_012988.1 3476717 3479581 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL), with PAS sensor, signal transduction histidine kinase and methyl-accepting chemotaxis domains; putative membrane-associated protein 3476717..3479581 Methylobacterium extorquens DM4 8193190 YP_003069035.1 CDS METDI3542 NC_012988.1 3479816 3480673 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative manganese catalase 3479816..3480673 Methylobacterium extorquens DM4 8193191 YP_003069036.1 CDS METDI3543 NC_012988.1 3480752 3481261 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3480752..3481261 Methylobacterium extorquens DM4 8193192 YP_003069037.1 CDS METDI3544 NC_012988.1 3481451 3482122 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative spermidine synthase complement(3481451..3482122) Methylobacterium extorquens DM4 8193193 YP_003069038.1 CDS METDI3545 NC_012988.1 3482211 3482462 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3482211..3482462 Methylobacterium extorquens DM4 8193194 YP_003069039.1 CDS METDI3546 NC_012988.1 3482753 3484696 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; putative chloride channel protein 3482753..3484696 Methylobacterium extorquens DM4 8196229 YP_003069040.1 CDS METDI3547 NC_012988.1 3484725 3485213 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3484725..3485213 Methylobacterium extorquens DM4 8193196 YP_003069041.1 CDS kdsA NC_012988.1 3485224 3486072 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 3485224..3486072 Methylobacterium extorquens DM4 8193197 YP_003069042.1 CDS METDI3549 NC_012988.1 3486249 3486560 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3486249..3486560 Methylobacterium extorquens DM4 8195619 YP_003069043.1 CDS METDI3550 NC_012988.1 3486890 3487351 R NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(3486890..3487351) Methylobacterium extorquens DM4 8193198 YP_003069044.1 CDS eno NC_012988.1 3487643 3488932 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3487643..3488932 Methylobacterium extorquens DM4 8193199 YP_003069045.1 CDS METDI3552 NC_012988.1 3489068 3489379 D Evidence 2b : Function of strongly homologous gene; Product type s : structure; Septum formation initiator 3489068..3489379 Methylobacterium extorquens DM4 8195330 YP_003069046.1 CDS pdhA NC_012988.1 3489555 3490604 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; pyruvate dehydrogenase E1 alpha subunit 3489555..3490604 Methylobacterium extorquens DM4 8193200 YP_003069047.1 CDS pdhB NC_012988.1 3490711 3492159 D catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 3490711..3492159 Methylobacterium extorquens DM4 8195837 YP_003069048.1 CDS METDI3555 NC_012988.1 3492170 3492448 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; hypothetical protein 3492170..3492448 Methylobacterium extorquens DM4 8195838 YP_003069049.1 CDS pdhC NC_012988.1 3492482 3493894 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12634329; Product type e : enzyme; dihydrolipoamide acetyltransferase 3492482..3493894 Methylobacterium extorquens DM4 8193201 YP_003069050.1 CDS lpd NC_012988.1 3494057 3495496 D E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 3494057..3495496 Methylobacterium extorquens DM4 8195839 YP_003069051.1 CDS METDI3558 NC_012988.1 3495757 3495909 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3495757..3495909 Methylobacterium extorquens DM4 8195645 YP_003069052.1 CDS METDI3559 NC_012988.1 3496005 3496517 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3496005..3496517) Methylobacterium extorquens DM4 8193202 YP_003069053.1 CDS METDI3560 NC_012988.1 3496495 3497229 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3496495..3497229) Methylobacterium extorquens DM4 8193203 YP_003069054.1 CDS METDI3561 NC_012988.1 3497510 3497683 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3497510..3497683 Methylobacterium extorquens DM4 8193204 YP_003069055.1 CDS METDI3562 NC_012988.1 3497771 3498406 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3497771..3498406 Methylobacterium extorquens DM4 8193205 YP_003069056.1 CDS METDI3563 NC_012988.1 3498575 3499921 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7574579; Product type e : enzyme; sorbosone dehydrogenase precursor (SNDH) complement(3498575..3499921) Methylobacterium extorquens DM4 8193206 YP_003069057.1 CDS METDI3564 NC_012988.1 3499943 3500149 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3499943..3500149) Methylobacterium extorquens DM4 8193207 YP_003069058.1 CDS METDI3565 NC_012988.1 3500360 3501097 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3500360..3501097 Methylobacterium extorquens DM4 8193208 YP_003069059.1 CDS lipA NC_012988.1 3501231 3502250 D catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 3501231..3502250 Methylobacterium extorquens DM4 8193209 YP_003069060.1 CDS METDI3567 NC_012988.1 3502305 3502715 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; cyclase/dehydrase 3502305..3502715 Methylobacterium extorquens DM4 8195636 YP_003069061.1 CDS METDI3568 NC_012988.1 3502800 3503225 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, AsnC/Lrp family complement(3502800..3503225) Methylobacterium extorquens DM4 8193210 YP_003069062.1 CDS arcB NC_012988.1 3503383 3504387 D catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 3503383..3504387 Methylobacterium extorquens DM4 8193211 YP_003069063.1 CDS METDI3570 NC_012988.1 3504700 3505740 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 3-oxoacyl-(Acyl-carrier-protein) synthase III 3504700..3505740 Methylobacterium extorquens DM4 8195081 YP_003069064.1 CDS METDI3571 NC_012988.1 3505760 3505993 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative acyl carrier protein 3505760..3505993 Methylobacterium extorquens DM4 8193212 YP_003069065.1 CDS METDI3572 NC_012988.1 3505994 3507040 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative keto/oxo acyl-ACP synthase 3505994..3507040 Methylobacterium extorquens DM4 8193213 YP_003069066.1 CDS METDI3573 NC_012988.1 3507037 3507798 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 3507037..3507798 Methylobacterium extorquens DM4 8193214 YP_003069067.1 CDS METDI3574 NC_012988.1 3507727 3508875 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Naphthalene 1,2-dioxygenase subunit alpha (Naphthalene 1,2-dioxygenase ISP alpha) complement(3507727..3508875) Methylobacterium extorquens DM4 8193215 YP_003069068.1 CDS METDI3575 NC_012988.1 3509282 3509932 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase 3509282..3509932 Methylobacterium extorquens DM4 8193216 YP_003069069.1 CDS METDI3576 NC_012988.1 3510123 3512276 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3510123..3512276) Methylobacterium extorquens DM4 8193217 YP_003069070.1 CDS METDI3577 NC_012988.1 3512443 3512781 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3512443..3512781) Methylobacterium extorquens DM4 8193218 YP_003069071.1 CDS METDI3578 NC_012988.1 3512778 3514565 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused ATPase and permease domains complement(3512778..3514565) Methylobacterium extorquens DM4 8193219 YP_003069072.1 CDS METDI3581 NC_012988.1 3515455 3515952 D Evidence 2b : Function of strongly homologous gene; PubMedId : 16377905; Product type e : enzyme; oxidoreductase, 2Fe-2S subunit 3515455..3515952 Methylobacterium extorquens DM4 8193220 YP_003069073.1 CDS METDI3582 NC_012988.1 3515949 3516998 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, FAD-binding subunit; putative molybdopterin oxidoreductase, xanthine dehydrogenase family 3515949..3516998 Methylobacterium extorquens DM4 8193221 YP_003069074.1 CDS METDI3583 NC_012988.1 3516991 3519234 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, molybdopterin-binding subunit 3516991..3519234 Methylobacterium extorquens DM4 8193222 YP_003069075.1 CDS METDI3584 NC_012988.1 3519383 3519910 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; CinA (competence-damaged protein) family protein complement(3519383..3519910) Methylobacterium extorquens DM4 8193223 YP_003069076.1 CDS ispDF NC_012988.1 3519907 3521190 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10518523, 11427897, 10694574; Product type e : enzyme; IspD/IspF bifunctional enzyme (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (MEP cytidylyltransferase, MCT); 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate synthase (MECPS, MECDP synthase)) complement(3519907..3521190) Methylobacterium extorquens DM4 8193224 YP_003069077.1 CDS dusB NC_012988.1 3521369 3522397 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1459953, 1547773, 22095566, 2835774, 2837762, 8226664; Product type e : enzyme; tRNA-dihydrouridine synthase B 3521369..3522397 Methylobacterium extorquens DM4 8195608 YP_003069078.1 CDS glnL NC_012988.1 3522397 3523530 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sensory histdine kinase (soluble) in two-component regulatory system with GlnG, nitrogen regulation (nitrogen regulator II, NRII); Domains: HK homodimeric, ATPase and PAS 3522397..3523530 Methylobacterium extorquens DM4 8195318 YP_003069079.1 CDS glnG NC_012988.1 3523541 3525013 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; N-terminal response receiver 3523541..3525013 Methylobacterium extorquens DM4 8195505 YP_003069080.1 CDS METDI3589 NC_012988.1 3525141 3526778 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative helicase domain protein, DEAD/DEAH motif 3525141..3526778 Methylobacterium extorquens DM4 8195501 YP_003069081.1 CDS ntrY NC_012988.1 3526872 3529241 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; nitrogen regulatory signal transduction histidine kinase NtrY 3526872..3529241 Methylobacterium extorquens DM4 8193225 YP_003069082.1 CDS glnG NC_012988.1 3529238 3530608 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; N-terminal response receiver 3529238..3530608 Methylobacterium extorquens DM4 8195786 YP_003069083.1 CDS hfq NC_012988.1 3530916 3531170 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; Protein hfq, RNA-binding host factor 3530916..3531170 Methylobacterium extorquens DM4 8195502 YP_003069084.1 CDS METDI3593 NC_012988.1 3531267 3532682 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3040675, 8248183; Product type pe : putative enzyme; putative GTPase (HflX) 3531267..3532682 Methylobacterium extorquens DM4 8195556 YP_003069085.1 CDS METDI3594 NC_012988.1 3532829 3534397 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Sulphate transporter complement(3532829..3534397) Methylobacterium extorquens DM4 8193226 YP_003069086.1 CDS cynT NC_012988.1 3534407 3535162 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3049588, 91242169, 1740425, 94075239; Product type e : enzyme; carbonic anhydrase complement(3534407..3535162) Methylobacterium extorquens DM4 8193227 YP_003069087.1 CDS METDI3596 NC_012988.1 3535459 3535770 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3535459..3535770) Methylobacterium extorquens DM4 8195242 YP_003069088.1 CDS METDI3597 NC_012988.1 3535898 3536188 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3535898..3536188) Methylobacterium extorquens DM4 8193228 YP_003069089.1 CDS METDI3598 NC_012988.1 3536612 3536998 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3536612..3536998) Methylobacterium extorquens DM4 8193229 YP_003069090.1 CDS METDI3599 NC_012988.1 3537028 3537405 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3537028..3537405) Methylobacterium extorquens DM4 8193230 YP_003069091.1 CDS METDI3600 NC_012988.1 3537432 3540608 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Heavy metal efflux pump CzcA (precursor) complement(3537432..3540608) Methylobacterium extorquens DM4 8193231 YP_003069092.1 CDS METDI3601 NC_012988.1 3540622 3542352 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3540622..3542352) Methylobacterium extorquens DM4 8193232 YP_003069093.1 CDS METDI3602 NC_012988.1 3542424 3542858 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3542424..3542858) Methylobacterium extorquens DM4 8193233 YP_003069094.1 CDS METDI3603 NC_012988.1 3543439 3543927 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, MucR family 3543439..3543927 Methylobacterium extorquens DM4 8193234 YP_003069095.1 CDS METDI3604 NC_012988.1 3544003 3544563 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3544003..3544563 Methylobacterium extorquens DM4 8193235 YP_003069096.1 CDS METDI3605 NC_012988.1 3544575 3546032 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative MCP methyltransferase, CheR-type 3544575..3546032 Methylobacterium extorquens DM4 8193236 YP_003069097.1 CDS METDI3606 NC_012988.1 3546029 3546586 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; cheW-like protein 3546029..3546586 Methylobacterium extorquens DM4 8193237 YP_003069098.1 CDS METDI3607 NC_012988.1 3546667 3548415 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; methyl-accepting chemotaxis sensory transducer 3546667..3548415 Methylobacterium extorquens DM4 8193238 YP_003069099.1 CDS METDI3608 NC_012988.1 3548440 3550686 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; signal transduction histidine kinase with N-terminal phosphotransfer and C-terminal response regulator receiver domains 3548440..3550686 Methylobacterium extorquens DM4 8193239 YP_003069100.1 CDS cheB NC_012988.1 3550710 3551768 D Evidence 2b : Function of strongly homologous gene; PubMedId : 3280143, 3510184, 89053899, 90008896, 93209955, 9687492, 99395068; Product type r : regulator; Chemotaxis response regulator protein-glutamate methylesterase 3550710..3551768 Methylobacterium extorquens DM4 8193240 YP_003069101.1 CDS METDI3610 NC_012988.1 3551765 3553498 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative Sensor protein, CheY-like domain 3551765..3553498 Methylobacterium extorquens DM4 8195163 YP_003069102.1 CDS METDI3611 NC_012988.1 3553495 3555363 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor hybrid histidine kinase with two PAS and two response regulator receiver domains 3553495..3555363 Methylobacterium extorquens DM4 8193241 YP_003069103.1 CDS METDI3612 NC_012988.1 3555719 3557029 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Cytochrome c, class I complement(3555719..3557029) Methylobacterium extorquens DM4 8193242 YP_003069104.1 CDS METDI3613 NC_012988.1 3557254 3558339 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative molybdopterin biosynthesis-related protein 3557254..3558339 Methylobacterium extorquens DM4 8193243 YP_003069105.1 CDS METDI3614 NC_012988.1 3558336 3560312 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein 3558336..3560312 Methylobacterium extorquens DM4 8193244 YP_003069106.1 CDS mobB NC_012988.1 3560309 3560845 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; molybdopterin-guanine dinucleotide biosynthesis protein B, GTP-binding 3560309..3560845 Methylobacterium extorquens DM4 8193245 YP_003069107.1 CDS METDI3616 NC_012988.1 3560849 3562099 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative molybdopterin biosynthesis-related protein 3560849..3562099 Methylobacterium extorquens DM4 8195708 YP_003069108.1 CDS METDI3617 NC_012988.1 3562154 3563194 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Regulatory protein, LysR complement(3562154..3563194) Methylobacterium extorquens DM4 8193246 YP_003069109.1 CDS METDI3618 NC_012988.1 3563275 3564015 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Sulfate/tungstate uptake transporter, membrane component of ABC transporter 3563275..3564015 Methylobacterium extorquens DM4 8193247 YP_003069110.1 CDS METDI3619 NC_012988.1 3564012 3564728 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Phosphate-transporting ATPase, ATP-binding component of ABC transporter 3564012..3564728 Methylobacterium extorquens DM4 8193248 YP_003069111.1 CDS modB1 NC_012988.1 3564701 3565528 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Molybdate or tungstate transport precursor 3564701..3565528 Methylobacterium extorquens DM4 8193249 YP_003069112.1 CDS METDI3621 NC_012988.1 3565697 3565933 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3565697..3565933) Methylobacterium extorquens DM4 8195712 YP_003069113.1 CDS METDI3622 NC_012988.1 3565977 3566621 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3565977..3566621) Methylobacterium extorquens DM4 8193250 YP_003069114.1 CDS mdoD NC_012988.1 3566690 3568147 R involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D complement(3566690..3568147) Methylobacterium extorquens DM4 8193251 YP_003069115.1 CDS METDI3624 NC_012988.1 3568416 3570332 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 3568416..3570332 Methylobacterium extorquens DM4 8193252 YP_003069116.1 CDS METDI3625 NC_012988.1 3570422 3570889 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3570422..3570889) Methylobacterium extorquens DM4 8193253 YP_003069117.1 CDS METDI3626 NC_012988.1 3570979 3572196 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15581575, 9843488; Product type e : enzyme; putative cystathionine gamma-synthase, PLP-dependent (metB) complement(3570979..3572196) Methylobacterium extorquens DM4 8193254 YP_003069118.1 CDS METDI3627 NC_012988.1 3572294 3572809 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11097914, 7673149; Product type prc : putative receptor; putative tryptophan-rich sensory protein; putative membrane protein; putative regulatory receptor protein 3572294..3572809 Methylobacterium extorquens DM4 8193255 YP_003069119.1 CDS METDI3628 NC_012988.1 3572970 3573335 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator (CheY-like protein) complement(3572970..3573335) Methylobacterium extorquens DM4 8193256 YP_003069120.1 CDS hpt NC_012988.1 3573499 3574068 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12070315; Product type e : enzyme; Hypoxanthine phosphoribosyl transferase complement(3573499..3574068) Methylobacterium extorquens DM4 8193257 YP_003069121.1 CDS METDI3630 NC_012988.1 3574257 3575012 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3574257..3575012) Methylobacterium extorquens DM4 8195575 YP_003069122.1 CDS ftsE NC_012988.1 3575170 3575883 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; transporter subunit: ATP-binding component of ABC superfamily 3575170..3575883 Methylobacterium extorquens DM4 8193258 YP_003069123.1 CDS METDI3632 NC_012988.1 3575880 3576860 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3575880..3576860 Methylobacterium extorquens DM4 8195449 YP_003069124.1 CDS METDI3633 NC_012988.1 3577102 3577806 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3577102..3577806 Methylobacterium extorquens DM4 8193259 YP_003069125.1 CDS METDI3634 NC_012988.1 3577893 3578267 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver complement(3577893..3578267) Methylobacterium extorquens DM4 8193260 YP_003069126.1 CDS proB NC_012988.1 3578540 3579673 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 3578540..3579673 Methylobacterium extorquens DM4 8193261 YP_003069127.1 CDS proA NC_012988.1 3579813 3581120 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 3579813..3581120 Methylobacterium extorquens DM4 8195902 YP_003069128.1 CDS nadD NC_012988.1 3581108 3581725 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15805518; Product type e : enzyme; nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase) (Deamido-NAD(+) diphosphorylase) (Nicotinate mononucleotide adenylyltransferase) (NaMN adenylyltransferase) 3581108..3581725 Methylobacterium extorquens DM4 8195901 YP_003069129.1 CDS METDI3639 NC_012988.1 3582168 3582470 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3582168..3582470 Methylobacterium extorquens DM4 8195768 YP_003069130.1 CDS METDI3640 NC_012988.1 3582479 3583174 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3582479..3583174) Methylobacterium extorquens DM4 8193262 YP_003069131.1 CDS METDI3641 NC_012988.1 3583228 3583746 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(3583228..3583746) Methylobacterium extorquens DM4 8193263 YP_003069132.1 CDS galM NC_012988.1 3583876 3584916 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12753898; Product type e : enzyme; Aldose-1-epimerase (Galactose mutarotase) complement(3583876..3584916) Methylobacterium extorquens DM4 8193264 YP_003069133.1 CDS METDI3643 NC_012988.1 3585013 3586806 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused ATPase and transmembrane permease domains complement(3585013..3586806) Methylobacterium extorquens DM4 8195463 YP_003069134.1 CDS METDI3644 NC_012988.1 3587078 3588007 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein 3587078..3588007 Methylobacterium extorquens DM4 8193265 YP_003069135.1 CDS moaD NC_012988.1 3588126 3588377 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; molybdopterin converting factor, subunit 1 complement(3588126..3588377) Methylobacterium extorquens DM4 8193266 YP_003069136.1 CDS pgsA NC_012988.1 3588432 3589130 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3003065; Product type e : enzyme; phosphatidylglycerophosphate synthetase complement(3588432..3589130) Methylobacterium extorquens DM4 8195705 YP_003069137.1 CDS uvrC NC_012988.1 3589117 3591165 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; DNA exisiton repair enzyme together with UvrAB complement(3589117..3591165) Methylobacterium extorquens DM4 8195853 YP_003069138.1 CDS METDI3648 NC_012988.1 3591261 3591986 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3591261..3591986) Methylobacterium extorquens DM4 8196331 YP_003069139.1 CDS METDI3649 NC_012988.1 3592216 3592938 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3592216..3592938 Methylobacterium extorquens DM4 8193267 YP_003069140.1 CDS METDI3650 NC_012988.1 3593018 3593749 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3593018..3593749) Methylobacterium extorquens DM4 8193268 YP_003069141.1 CDS METDI3651 NC_012988.1 3594078 3594950 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative 31 kDa outer-membrane immunogenic protein precursor (omp31) complement(3594078..3594950) Methylobacterium extorquens DM4 8193269 YP_003069142.1 CDS METDI3652 NC_012988.1 3595347 3596114 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3595347..3596114) Methylobacterium extorquens DM4 8193270 YP_003069143.1 CDS METDI3653 NC_012988.1 3596154 3597239 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3596154..3597239) Methylobacterium extorquens DM4 8193271 YP_003069144.1 CDS lgt NC_012988.1 3597242 3598132 R Evidence 2b : Function of strongly homologous gene; PubMedId : 94327509; Product type e : enzyme; Prolipoprotein diacylglyceryl transferase complement(3597242..3598132) Methylobacterium extorquens DM4 8193272 YP_003069145.1 CDS METDI3655 NC_012988.1 3598274 3598954 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MgtC family protein 3598274..3598954 Methylobacterium extorquens DM4 8195634 YP_003069146.1 CDS pgm NC_012988.1 3599058 3600689 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 3599058..3600689 Methylobacterium extorquens DM4 8193273 YP_003069147.1 CDS METDI3657 NC_012988.1 3600686 3601123 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3600686..3601123 Methylobacterium extorquens DM4 8195851 YP_003069148.1 CDS METDI3658 NC_012988.1 3601087 3601956 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3601087..3601956 Methylobacterium extorquens DM4 8193274 YP_003069149.1 CDS METDI3659 NC_012988.1 3602130 3603035 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cell wall hydrolase complement(3602130..3603035) Methylobacterium extorquens DM4 8193275 YP_003069150.1 CDS METDI3660 NC_012988.1 3603142 3603333 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3603142..3603333) Methylobacterium extorquens DM4 8193276 YP_003069151.1 CDS ppdK NC_012988.1 3603586 3606252 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(3603586..3606252) Methylobacterium extorquens DM4 8193277 YP_003069152.1 CDS METDI3662 NC_012988.1 3606470 3606622 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3606470..3606622) Methylobacterium extorquens DM4 8195882 YP_003069153.1 CDS METDI3663 NC_012988.1 3606858 3607532 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3606858..3607532) Methylobacterium extorquens DM4 8193278 YP_003069154.1 CDS METDI3664 NC_012988.1 3607719 3608162 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; lactoylglutathione lyase family protein 3607719..3608162 Methylobacterium extorquens DM4 8193279 YP_003069155.1 CDS METDI3665 NC_012988.1 3608245 3608505 D Evidence 6 : Doubtful CDS; hypothetical protein 3608245..3608505 Methylobacterium extorquens DM4 8193280 YP_003069156.1 CDS METDI3666 NC_012988.1 3608551 3609000 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3608551..3609000) Methylobacterium extorquens DM4 8193281 YP_003069157.1 CDS METDI3667 NC_012988.1 3609907 3610380 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8022282, 9194707; Product type pr : putative regulator; putative transcriptional regulator, MarR family complement(3609907..3610380) Methylobacterium extorquens DM4 8193282 YP_003069158.1 CDS METDI3668 NC_012988.1 3610505 3611284 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3610505..3611284 Methylobacterium extorquens DM4 8193283 YP_003069159.1 CDS METDI3669 NC_012988.1 3611304 3612236 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3611304..3612236) Methylobacterium extorquens DM4 8193284 YP_003069160.1 CDS METDI3670 NC_012988.1 3612316 3613314 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3612316..3613314) Methylobacterium extorquens DM4 8193285 YP_003069161.1 CDS METDI3671 NC_012988.1 3614047 3614223 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3614047..3614223 Methylobacterium extorquens DM4 8193286 YP_003069162.1 CDS nepR NC_012988.1 3614302 3614550 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type f : factor; anti-sigma factor complement(3614302..3614550) Methylobacterium extorquens DM4 8193287 YP_003069163.1 CDS phyR NC_012988.1 3614724 3615506 D in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator 3614724..3615506 Methylobacterium extorquens DM4 8195775 YP_003069164.1 CDS METDI3674 NC_012988.1 3615967 3616329 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3615967..3616329 Methylobacterium extorquens DM4 8195865 YP_003069165.1 CDS METDI3675 NC_012988.1 3616427 3616966 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3616427..3616966) Methylobacterium extorquens DM4 8193288 YP_003069166.1 CDS METDI3676 NC_012988.1 3617089 3618480 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative aminotransferase 3617089..3618480 Methylobacterium extorquens DM4 8193289 YP_003069167.1 CDS METDI3677 NC_012988.1 3618827 3619042 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3618827..3619042 Methylobacterium extorquens DM4 8193290 YP_003069168.1 CDS METDI3678 NC_012988.1 3619080 3619994 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3619080..3619994 Methylobacterium extorquens DM4 8193291 YP_003069169.1 CDS METDI3679 NC_012988.1 3620010 3620228 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3620010..3620228) Methylobacterium extorquens DM4 8193292 YP_003069170.1 CDS METDI3680 NC_012988.1 3620285 3620722 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase complement(3620285..3620722) Methylobacterium extorquens DM4 8193293 YP_003069171.1 CDS METDI3681 NC_012988.1 3620719 3621642 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(3620719..3621642) Methylobacterium extorquens DM4 8193294 YP_003069172.1 CDS METDI3682 NC_012988.1 3621692 3621979 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3621692..3621979) Methylobacterium extorquens DM4 8193295 YP_003069173.1 CDS rnd NC_012988.1 3622140 3623294 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Ribonuclease D (RNase D) complement(3622140..3623294) Methylobacterium extorquens DM4 8193296 YP_003069174.1 CDS METDI3684 NC_012988.1 3623390 3623698 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3623390..3623698) Methylobacterium extorquens DM4 8196002 YP_003069175.1 CDS METDI3685 NC_012988.1 3623994 3625205 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative penicillin binding protein, beta-lactamase/transpeptidase-like superfamily 3623994..3625205 Methylobacterium extorquens DM4 8193297 YP_003069176.1 CDS METDI3686 NC_012988.1 3625245 3627143 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3625245..3627143) Methylobacterium extorquens DM4 8193298 YP_003069177.1 CDS atoD NC_012988.1 3627529 3628266 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit 3627529..3628266 Methylobacterium extorquens DM4 8193299 YP_003069178.1 CDS atoA NC_012988.1 3628375 3629034 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; acetyl-CoA:acetoacetyl-CoA transferase, beta subunit 3628375..3629034 Methylobacterium extorquens DM4 8195114 YP_003069179.1 CDS METDI3689 NC_012988.1 3629206 3629613 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3629206..3629613 Methylobacterium extorquens DM4 8195113 YP_003069180.1 CDS METDI3690 NC_012988.1 3629793 3630161 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3629793..3630161 Methylobacterium extorquens DM4 8193300 YP_003069181.1 CDS METDI3691 NC_012988.1 3630201 3631583 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8760927; Product type m : membrane component; hypothetical protein 3630201..3631583 Methylobacterium extorquens DM4 8193301 YP_003069182.1 CDS METDI3692 NC_012988.1 3631644 3633974 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent receptor protein precursor 3631644..3633974 Methylobacterium extorquens DM4 8193302 YP_003069183.1 CDS METDI3693 NC_012988.1 3634055 3635005 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3634055..3635005) Methylobacterium extorquens DM4 8193303 YP_003069184.1 CDS METDI3694 NC_012988.1 3634980 3635795 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12228263; Product type pt : putative transporter; putative ABC transporter, ATPase; putative iron transporter complement(3634980..3635795) Methylobacterium extorquens DM4 8193304 YP_003069185.1 CDS METDI3695 NC_012988.1 3635792 3636832 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, permease precursor, putative iron transporter complement(3635792..3636832) Methylobacterium extorquens DM4 8193305 YP_003069186.1 CDS METDI3696 NC_012988.1 3636829 3637662 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein; putative iron transporter complement(3636829..3637662) Methylobacterium extorquens DM4 8193306 YP_003069187.1 CDS METDI3697 NC_012988.1 3637827 3638177 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3637827..3638177 Methylobacterium extorquens DM4 8193307 YP_003069188.1 CDS METDI3698 NC_012988.1 3638177 3638602 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3638177..3638602 Methylobacterium extorquens DM4 8193308 YP_003069189.1 CDS guaA NC_012988.1 3638652 3640217 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(3638652..3640217) Methylobacterium extorquens DM4 8193309 YP_003069190.1 CDS METDI3700 NC_012988.1 3640387 3640614 D Evidence 6 : Doubtful CDS; hypothetical protein 3640387..3640614 Methylobacterium extorquens DM4 8195539 YP_003069191.1 CDS METDI3701 NC_012988.1 3640800 3641357 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3640800..3641357) Methylobacterium extorquens DM4 8193310 YP_003069192.1 CDS METDI3702 NC_012988.1 3641520 3642548 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12730169; Product type pe : putative enzyme; putative pectin acetylesterase precursor; putative alpha-beta hydrolase precursor complement(3641520..3642548) Methylobacterium extorquens DM4 8193311 YP_003069193.1 CDS METDI3703 NC_012988.1 3642684 3644033 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative SUN-family protein, RNA methyltransferase complement(3642684..3644033) Methylobacterium extorquens DM4 8193312 YP_003069194.1 CDS METDI3704 NC_012988.1 3644129 3644317 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3644129..3644317 Methylobacterium extorquens DM4 8193313 YP_003069195.1 CDS METDI3705 NC_012988.1 3644421 3645359 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3644421..3645359) Methylobacterium extorquens DM4 8193314 YP_003069196.1 CDS METDI3706 NC_012988.1 3645566 3646450 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3645566..3646450 Methylobacterium extorquens DM4 8193315 YP_003069197.1 CDS METDI3707 NC_012988.1 3646774 3647619 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3646774..3647619 Methylobacterium extorquens DM4 8193316 YP_003069198.1 CDS guaB NC_012988.1 3648148 3649638 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2860637; Product type e : enzyme; IMP dehydrogeanse complement(3648148..3649638) Methylobacterium extorquens DM4 8193317 YP_003069199.1 CDS METDI3709 NC_012988.1 3649619 3649822 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3649619..3649822) Methylobacterium extorquens DM4 8195540 YP_003069200.1 CDS ftsW NC_012988.1 3649902 3651068 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7830569, 9218774; Product type cp : cell process; Cell division protein 3649902..3651068 Methylobacterium extorquens DM4 8193318 YP_003069201.1 CDS murG NC_012988.1 3651065 3652174 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10892798, 1387377; Product type e : enzyme; Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3651065..3652174 Methylobacterium extorquens DM4 8195455 YP_003069202.1 CDS murC NC_012988.1 3652316 3653722 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 3652316..3653722 Methylobacterium extorquens DM4 8195742 YP_003069203.1 CDS METDI3713 NC_012988.1 3653739 3654128 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative phage-related transcriptional regulator complement(3653739..3654128) Methylobacterium extorquens DM4 8195738 YP_003069204.1 CDS METDI3714 NC_012988.1 3654139 3654345 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3654139..3654345) Methylobacterium extorquens DM4 8193319 YP_003069205.1 CDS murB NC_012988.1 3654441 3655370 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12757953, 14551189, 8448160; Product type e : enzyme; UDP-N-acetylenolpyruvoylglucosamine reductase 3654441..3655370 Methylobacterium extorquens DM4 8193320 YP_003069206.1 CDS ddl NC_012988.1 3655414 3656337 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 3655414..3656337 Methylobacterium extorquens DM4 8195737 YP_003069207.1 CDS METDI3717 NC_012988.1 3656304 3657242 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9352931; Product type cp : cell process; putative cell division protein (FtsQ-like) 3656304..3657242 Methylobacterium extorquens DM4 8195283 YP_003069208.1 CDS ftsA NC_012988.1 3657368 3658627 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11847116, 2846985, 2995680, 9352931; Product type cp : cell process; cell division protein FtsA 3657368..3658627 Methylobacterium extorquens DM4 8193321 YP_003069209.1 CDS ftsZ NC_012988.1 3658833 3660590 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1653222, 9352931; Product type cp : cell process; Cell division GTPase 3658833..3660590 Methylobacterium extorquens DM4 8195448 YP_003069210.1 CDS lpxC NC_012988.1 3660941 3661888 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3660941..3661888 Methylobacterium extorquens DM4 8195457 YP_003069211.1 CDS METDI3721 NC_012988.1 3662054 3662929 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8830266; Product type lp : lipoprotein; putative lipoprotein UPF0169; putative exported protein 3662054..3662929 Methylobacterium extorquens DM4 8195648 YP_003069212.1 CDS METDI3722 NC_012988.1 3663198 3664184 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3663198..3664184) Methylobacterium extorquens DM4 8193322 YP_003069213.1 CDS recN NC_012988.1 3664340 3666040 D Evidence 2b : Function of strongly homologous gene; PubMedId : 3037486; Product type cp : cell process; DNA repair protein RecN 3664340..3666040 Methylobacterium extorquens DM4 8193323 YP_003069214.1 CDS METDI3724 NC_012988.1 3666037 3666330 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3666037..3666330) Methylobacterium extorquens DM4 8195972 YP_003069215.1 CDS METDI3725 NC_012988.1 3666414 3666686 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3666414..3666686) Methylobacterium extorquens DM4 8193324 YP_003069216.1 CDS METDI3726 NC_012988.1 3666718 3667410 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3666718..3667410) Methylobacterium extorquens DM4 8193325 YP_003069217.1 CDS METDI3727 NC_012988.1 3667552 3669867 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative molybdopterin oxidoreductase complement(3667552..3669867) Methylobacterium extorquens DM4 8193326 YP_003069218.1 CDS METDI3728 NC_012988.1 3669970 3671046 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3669970..3671046) Methylobacterium extorquens DM4 8193327 YP_003069219.1 CDS dnaK NC_012988.1 3671392 3673311 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9061015; Product type f : factor; Chaperone protein DnaK 3671392..3673311 Methylobacterium extorquens DM4 8193328 YP_003069220.1 CDS dnaJ NC_012988.1 3673509 3674720 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; heat shock protein (Hsp40), co-chaperone with DnaK 3673509..3674720 Methylobacterium extorquens DM4 8195308 YP_003069221.1 CDS pmtA NC_012988.1 3674879 3675535 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phospholipid N-methyltransferase 3674879..3675535 Methylobacterium extorquens DM4 8195307 YP_003069222.1 CDS METDI3732 NC_012988.1 3675783 3676127 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3675783..3676127 Methylobacterium extorquens DM4 8195868 YP_003069223.1 CDS deoA NC_012988.1 3676155 3677465 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6286410, 6323164; Product type e : enzyme; thymidine phosphorylase complement(3676155..3677465) Methylobacterium extorquens DM4 8193329 YP_003069224.1 CDS deoC NC_012988.1 3677462 3678235 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11598300; Product type e : enzyme; 2-deoxyribose-5-phosphate aldolase, NAD(P)-linked complement(3677462..3678235) Methylobacterium extorquens DM4 8195286 YP_003069225.1 CDS xapA NC_012988.1 3678245 3679057 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(3678245..3679057) Methylobacterium extorquens DM4 8195288 YP_003069226.1 CDS cdd NC_012988.1 3679047 3679460 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15689149; Product type e : enzyme; cytidine deaminase (cytidine aminohydrolase) complement(3679047..3679460) Methylobacterium extorquens DM4 8196336 YP_003069227.1 CDS METDI3737 NC_012988.1 3679606 3679830 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3679606..3679830 Methylobacterium extorquens DM4 8195159 YP_003069228.1 CDS lpxK NC_012988.1 3679913 3680896 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9268317; Product type e : enzyme; Tetraacyldisaccharide 4'-kinase complement(3679913..3680896) Methylobacterium extorquens DM4 8193330 YP_003069229.1 CDS METDI3739 NC_012988.1 3680904 3682208 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2033061; Product type e : enzyme; putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase encoded by kdtA) complement(3680904..3682208) Methylobacterium extorquens DM4 8195650 YP_003069230.1 CDS METDI3740 NC_012988.1 3682205 3682954 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3682205..3682954) Methylobacterium extorquens DM4 8193331 YP_003069231.1 CDS METDI3741 NC_012988.1 3683191 3684138 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallophosphatase/metallophosphoesterase 3683191..3684138 Methylobacterium extorquens DM4 8193332 YP_003069232.1 CDS METDI3742 NC_012988.1 3684154 3684630 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; response regulator receiver complement(3684154..3684630) Methylobacterium extorquens DM4 8193333 YP_003069233.1 CDS METDI3744 NC_012988.1 3685012 3685848 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, cold shock protein 3685012..3685848 Methylobacterium extorquens DM4 8193334 YP_003069234.1 CDS METDI3745 NC_012988.1 3685977 3686222 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3685977..3686222 Methylobacterium extorquens DM4 8193335 YP_003069235.1 CDS METDI3746 NC_012988.1 3686251 3687660 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; leucine aminopeptidase complement(3686251..3687660) Methylobacterium extorquens DM4 8193336 YP_003069236.1 CDS METDI3747 NC_012988.1 3687758 3688606 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3687758..3688606 Methylobacterium extorquens DM4 8193337 YP_003069237.1 CDS rpmB NC_012988.1 3688792 3689097 D required for 70S ribosome assembly; 50S ribosomal protein L28 3688792..3689097 Methylobacterium extorquens DM4 8193338 YP_003069238.1 CDS METDI3749 NC_012988.1 3689210 3690139 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease 3689210..3690139 Methylobacterium extorquens DM4 8196036 YP_003069239.1 CDS lysK NC_012988.1 3690248 3691996 D class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 3690248..3691996 Methylobacterium extorquens DM4 8193339 YP_003069240.1 CDS METDI3751 NC_012988.1 3692143 3692637 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3692143..3692637) Methylobacterium extorquens DM4 8195657 YP_003069241.1 CDS prfB NC_012988.1 3692877 3693842 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; peptide chain release factor RF-2 3692877..3693842 Methylobacterium extorquens DM4 8193340 YP_003069242.1 CDS METDI3753 NC_012988.1 3693987 3695165 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase precursor complement(3693987..3695165) Methylobacterium extorquens DM4 8195895 YP_003069243.1 CDS METDI3754 NC_012988.1 3695340 3695807 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thiol peroxidase, putative peroxiredoxin complement(3695340..3695807) Methylobacterium extorquens DM4 8193341 YP_003069244.1 CDS METDI3755 NC_012988.1 3695958 3699413 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3695958..3699413 Methylobacterium extorquens DM4 8193342 YP_003069245.1 CDS METDI3756 NC_012988.1 3700011 3701087 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9555904; Product type pe : putative enzyme; putative fatty acid desaturase ; putative membrane protein 3700011..3701087 Methylobacterium extorquens DM4 8193343 YP_003069246.1 CDS tyrS NC_012988.1 3701150 3702421 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; tyrosine tRNA synthetase complement(3701150..3702421) Methylobacterium extorquens DM4 8193344 YP_003069247.1 CDS anmK NC_012988.1 3702562 3703695 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 3702562..3703695 Methylobacterium extorquens DM4 8196292 YP_003069248.1 CDS METDI3759 NC_012988.1 3703692 3704309 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3703692..3704309 Methylobacterium extorquens DM4 8193345 YP_003069249.1 CDS METDI3760 NC_012988.1 3704303 3704617 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(3704303..3704617) Methylobacterium extorquens DM4 8193346 YP_003069250.1 CDS aroC NC_012988.1 3704694 3705794 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3704694..3705794 Methylobacterium extorquens DM4 8193347 YP_003069251.1 CDS ribAB NC_012988.1 3705923 3707002 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II 3705923..3707002 Methylobacterium extorquens DM4 8195093 YP_003069252.1 CDS METDI3763 NC_012988.1 3707214 3707342 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3707214..3707342 Methylobacterium extorquens DM4 8195992 YP_003069253.1 CDS METDI3764 NC_012988.1 3707367 3708218 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Histone deacetylase family protein complement(3707367..3708218) Methylobacterium extorquens DM4 8193348 YP_003069254.1 CDS METDI3765 NC_012988.1 3708597 3709235 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3708597..3709235 Methylobacterium extorquens DM4 8193349 YP_003069255.1 CDS METDI3766 NC_012988.1 3709408 3709866 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3709408..3709866 Methylobacterium extorquens DM4 8193350 YP_003069256.1 CDS pccA NC_012988.1 3710094 3712097 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156, 15188393, 16926146; Product type e : enzyme; propionyl-CoA carboxylase alpha subunit 3710094..3712097 Methylobacterium extorquens DM4 8193351 YP_003069257.1 CDS METDI3768 NC_012988.1 3712286 3712717 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3712286..3712717 Methylobacterium extorquens DM4 8195832 YP_003069258.1 CDS METDI3769 NC_012988.1 3712756 3712938 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3712756..3712938 Methylobacterium extorquens DM4 8193352 YP_003069259.1 CDS acyP NC_012988.1 3712991 3713275 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15159579, 15213401; Product type e : enzyme; Acylphosphatase (Acylphosphate phosphohydrolase) 3712991..3713275 Methylobacterium extorquens DM4 8193353 YP_003069260.1 CDS METDI3771 NC_012988.1 3713377 3714090 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3713377..3714090 Methylobacterium extorquens DM4 8195061 YP_003069261.1 CDS METDI3772 NC_012988.1 3714080 3714343 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3714080..3714343 Methylobacterium extorquens DM4 8193354 YP_003069262.1 CDS METDI3773 NC_012988.1 3714351 3715148 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3714351..3715148) Methylobacterium extorquens DM4 8193355 YP_003069263.1 CDS METDI3774 NC_012988.1 3715210 3715833 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(3715210..3715833) Methylobacterium extorquens DM4 8193356 YP_003069264.1 CDS METDI3775 NC_012988.1 3715830 3716891 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10629195, 16166264, 2019591; Product type pe : putative enzyme; putative aminomutase, putative homologue kamA and yjeK complement(3715830..3716891) Methylobacterium extorquens DM4 8193357 YP_003069265.1 CDS METDI3776 NC_012988.1 3716888 3717946 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative lysyl-tRNA synthetase (poxA-like) complement(3716888..3717946) Methylobacterium extorquens DM4 8193358 YP_003069266.1 CDS efp NC_012988.1 3718076 3718636 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 3718076..3718636 Methylobacterium extorquens DM4 8193359 YP_003069267.1 CDS METDI3778 NC_012988.1 3718812 3719798 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3718812..3719798) Methylobacterium extorquens DM4 8195327 YP_003069268.1 CDS METDI3779 NC_012988.1 3720221 3720766 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative tandem cold-shock DNA-binding domain protein 3720221..3720766 Methylobacterium extorquens DM4 8193360 YP_003069269.1 CDS METDI3780 NC_012988.1 3720763 3721293 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3720763..3721293 Methylobacterium extorquens DM4 8193361 YP_003069270.1 CDS bchD NC_012988.1 3721299 3723047 D involved in chelation of magnesium into protoporphyrin IX; involved in bacteriochlorophyll biosynthesis; part of a complex with BchI, BchD, and BchH; magnesium chelatase subunit D 3721299..3723047 Methylobacterium extorquens DM4 8193362 YP_003069271.1 CDS METDI3782 NC_012988.1 3723062 3723961 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative alpha/beta hydrolase, putative magnesium chelatase accessory protein 3723062..3723961 Methylobacterium extorquens DM4 8195127 YP_003069272.1 CDS crtI NC_012988.1 3724006 3725532 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10648776, 7721699, 8021167; Product type e : enzyme; phytoene dehydrogenase (phytoene desaturase) 3724006..3725532 Methylobacterium extorquens DM4 8193363 YP_003069273.1 CDS crtB NC_012988.1 3725513 3726574 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10648776, 7721699, 8021167; Product type e : enzyme; phytoene synthase 3725513..3726574 Methylobacterium extorquens DM4 8195220 YP_003069274.1 CDS ureG NC_012988.1 3726651 3727265 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2211515; Product type f : factor; urease accessory protein UreG complement(3726651..3727265) Methylobacterium extorquens DM4 8195216 YP_003069275.1 CDS ureF NC_012988.1 3727281 3728027 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2211515; Product type f : factor; urease accessory protein UreF complement(3727281..3728027) Methylobacterium extorquens DM4 8196327 YP_003069276.1 CDS ureE NC_012988.1 3727960 3728451 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11591723, 2211515, 8318889; Product type f : factor; urease accessory protein UreE complement(3727960..3728451) Methylobacterium extorquens DM4 8196323 YP_003069277.1 CDS METDI3788 NC_012988.1 3728456 3728941 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3728456..3728941) Methylobacterium extorquens DM4 8196320 YP_003069278.1 CDS ureC NC_012988.1 3728974 3730701 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(3728974..3730701) Methylobacterium extorquens DM4 8193364 YP_003069279.1 CDS METDI3790 NC_012988.1 3730704 3731264 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3730704..3731264) Methylobacterium extorquens DM4 8196315 YP_003069280.1 CDS ureAB NC_012988.1 3731261 3731881 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10844692, 1452359, 2001995, 2188975, 2318539, 2326167, 9252185; Product type e : enzyme; urease gamma (N-terminal) and beta (C-terminal) subunits (urea amidohydrolase gamma/beta subunits) complement(3731261..3731881) Methylobacterium extorquens DM4 8193365 YP_003069281.1 CDS ureD NC_012988.1 3731962 3732891 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7813887; Product type f : factor; urease accessory protein D complement(3731962..3732891) Methylobacterium extorquens DM4 8196310 YP_003069282.1 CDS METDI3793 NC_012988.1 3733101 3733619 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; flavin:NADH oxidoreductase, putative alternative pyrimidine degradation enzyme 3733101..3733619 Methylobacterium extorquens DM4 8196318 YP_003069283.1 CDS METDI3794 NC_012988.1 3733778 3734026 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3733778..3734026) Methylobacterium extorquens DM4 8193366 YP_003069284.1 CDS METDI3795 NC_012988.1 3734285 3734641 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3734285..3734641 Methylobacterium extorquens DM4 8193367 YP_003069285.1 CDS METDI3796 NC_012988.1 3734644 3736002 R catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway.; hydroxydechloroatrazine ethylaminohydrolase complement(3734644..3736002) Methylobacterium extorquens DM4 8193368 YP_003069286.1 CDS METDI3797 NC_012988.1 3736382 3737002 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3736382..3737002 Methylobacterium extorquens DM4 8193369 YP_003069287.1 CDS METDI3798 NC_012988.1 3737079 3737312 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3737079..3737312) Methylobacterium extorquens DM4 8193370 YP_003069288.1 CDS lspL NC_012988.1 3737856 3738869 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9765575; Product type e : enzyme; UDP-glucuronate 5'-epimerase (UDP-glucuronic acid epimerase) 3737856..3738869 Methylobacterium extorquens DM4 8193371 YP_003069289.1 CDS ugdH NC_012988.1 3739102 3740418 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9765575; Product type e : enzyme; UDP-glucose-6-dehydrogenase 3739102..3740418 Methylobacterium extorquens DM4 8195654 YP_003069290.1 CDS METDI3801 NC_012988.1 3740473 3740895 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3740473..3740895) Methylobacterium extorquens DM4 8196298 YP_003069292.1 CDS METDI3803 NC_012988.1 3741374 3741601 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3741374..3741601 Methylobacterium extorquens DM4 8193373 YP_003069293.1 CDS METDI3805 NC_012988.1 3741912 3742184 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3741912..3742184 Methylobacterium extorquens DM4 8193374 YP_003069294.1 CDS ilvA NC_012988.1 3742255 3743787 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; threonine deaminase complement(3742255..3743787) Methylobacterium extorquens DM4 8193375 YP_003069295.1 CDS METDI3807 NC_012988.1 3743888 3744463 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3743888..3744463) Methylobacterium extorquens DM4 8195592 YP_003069296.1 CDS METDI3808 NC_012988.1 3744472 3744675 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3744472..3744675 Methylobacterium extorquens DM4 8193376 YP_003069297.1 CDS METDI3809 NC_012988.1 3744902 3745120 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3744902..3745120 Methylobacterium extorquens DM4 8193377 YP_003069298.1 CDS METDI3810 NC_012988.1 3745174 3745470 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3745174..3745470 Methylobacterium extorquens DM4 8193378 YP_003069299.1 CDS dksA NC_012988.1 3745492 3745911 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; DnaK suppressor protein complement(3745492..3745911) Methylobacterium extorquens DM4 8193379 YP_003069300.1 CDS METDI3812 NC_012988.1 3745938 3746150 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3745938..3746150) Methylobacterium extorquens DM4 8195298 YP_003069301.1 CDS METDI3813 NC_012988.1 3746165 3747184 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3746165..3747184) Methylobacterium extorquens DM4 8193380 YP_003069302.1 CDS METDI3814 NC_012988.1 3747186 3748559 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative alginate o-acetyltransferase AlgI complement(3747186..3748559) Methylobacterium extorquens DM4 8193381 YP_003069303.1 CDS METDI3815 NC_012988.1 3748930 3749226 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3748930..3749226 Methylobacterium extorquens DM4 8193382 YP_003069304.1 CDS METDI3816 NC_012988.1 3749271 3749711 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9555902; Product type f : factor; putative Flagellar assembly protein fliX complement(3749271..3749711) Methylobacterium extorquens DM4 8193383 YP_003069305.1 CDS flgI NC_012988.1 3749965 3751107 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 3749965..3751107 Methylobacterium extorquens DM4 8193384 YP_003069306.1 CDS METDI3818 NC_012988.1 3751134 3751493 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3751134..3751493 Methylobacterium extorquens DM4 8195405 YP_003069307.1 CDS METDI3819 NC_012988.1 3751483 3751962 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3751483..3751962 Methylobacterium extorquens DM4 8193385 YP_003069308.1 CDS METDI3820 NC_012988.1 3752301 3752477 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3752301..3752477 Methylobacterium extorquens DM4 8193386 YP_003069309.1 CDS flgH NC_012988.1 3752703 3753455 R part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein complement(3752703..3753455) Methylobacterium extorquens DM4 8193387 YP_003069310.1 CDS flgA NC_012988.1 3753512 3754558 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; Flageller protein FlgA complement(3753512..3754558) Methylobacterium extorquens DM4 8195403 YP_003069311.1 CDS flgG NC_012988.1 3754573 3755364 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; flagellar biosynthesis; cell-distal portion of basal-body rod complement(3754573..3755364) Methylobacterium extorquens DM4 8195390 YP_003069312.1 CDS flgF NC_012988.1 3755391 3756131 R FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagellum; flagellar basal body rod protein FlgF complement(3755391..3756131) Methylobacterium extorquens DM4 8195401 YP_003069313.1 CDS fliL NC_012988.1 3756405 3756923 D interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 3756405..3756923 Methylobacterium extorquens DM4 8195399 YP_003069314.1 CDS fliM NC_012988.1 3757003 3758223 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar motor switch protein FliM 3757003..3758223 Methylobacterium extorquens DM4 8195422 YP_003069315.1 CDS METDI3827 NC_012988.1 3758237 3758725 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3758237..3758725 Methylobacterium extorquens DM4 8195424 YP_003069316.1 CDS METDI3828 NC_012988.1 3758722 3759519 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3758722..3759519 Methylobacterium extorquens DM4 8193388 YP_003069317.1 CDS METDI3829 NC_012988.1 3759523 3760017 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2671656, 3528129, 89364713; Product type pe : putative enzyme; putative Glutathione peroxidase complement(3759523..3760017) Methylobacterium extorquens DM4 8193389 YP_003069318.1 CDS METDI3830 NC_012988.1 3760348 3761037 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3760348..3761037 Methylobacterium extorquens DM4 8193390 YP_003069319.1 CDS METDI3831 NC_012988.1 3761084 3762325 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane bound lytic murein transglycosylase B, mltB 3761084..3762325 Methylobacterium extorquens DM4 8193391 YP_003069320.1 CDS METDI3832 NC_012988.1 3762332 3762913 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)H quinone oxidoreductasease 3762332..3762913 Methylobacterium extorquens DM4 8193392 YP_003069321.1 CDS METDI3833 NC_012988.1 3762953 3763837 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; hypothetical protein complement(3762953..3763837) Methylobacterium extorquens DM4 8193393 YP_003069322.1 CDS METDI3834 NC_012988.1 3764066 3764461 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3764066..3764461) Methylobacterium extorquens DM4 8193394 YP_003069323.1 CDS dctA NC_012988.1 3764666 3766009 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10482502, 4568614; Product type t : transporter; citrate and C4-dicarboxylic acids transport protein (DAACS family) complement(3764666..3766009) Methylobacterium extorquens DM4 8193395 YP_003069324.1 CDS METDI3836 NC_012988.1 3766321 3768198 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative sensor histidine kinase, putative transcriptional regulator of C4 dicarboxylate transporter 3766321..3768198 Methylobacterium extorquens DM4 8195280 YP_003069325.1 CDS METDI3837 NC_012988.1 3768195 3769547 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2134335, 2793824; Product type r : regulator; two-component DctB-like sigma-54 specific transcriptional regulator, Fis subfamily; with N-terminal response regulator receiver and ATPase domains 3768195..3769547 Methylobacterium extorquens DM4 8193396 YP_003069326.1 CDS METDI3838 NC_012988.1 3769561 3770619 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF motif) complement(3769561..3770619) Methylobacterium extorquens DM4 8193397 YP_003069327.1 CDS METDI3839 NC_012988.1 3770874 3773885 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL), with GAF and two PAS/PAC sensor domains complement(3770874..3773885) Methylobacterium extorquens DM4 8193398 YP_003069328.1 CDS gatB NC_012988.1 3774304 3775776 R Evidence 2b : Function of strongly homologous gene; PubMedId : 14704707; Product type e : enzyme; Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B) complement(3774304..3775776) Methylobacterium extorquens DM4 8193399 YP_003069329.1 CDS METDI3841 NC_012988.1 3775891 3776061 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3775891..3776061) Methylobacterium extorquens DM4 8195470 YP_003069330.1 CDS METDI3842 NC_012988.1 3776093 3776980 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative cation efflux pump fieF complement(3776093..3776980) Methylobacterium extorquens DM4 8193400 YP_003069331.1 CDS METDI3843 NC_012988.1 3777054 3777317 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3777054..3777317) Methylobacterium extorquens DM4 8193401 YP_003069332.1 CDS METDI3844 NC_012988.1 3777350 3777598 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3777350..3777598) Methylobacterium extorquens DM4 8193402 YP_003069333.1 CDS METDI3845 NC_012988.1 3777682 3779142 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Monooxygenase, FAD-binding complement(3777682..3779142) Methylobacterium extorquens DM4 8193403 YP_003069334.1 CDS queA NC_012988.1 3779235 3780341 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3779235..3780341 Methylobacterium extorquens DM4 8193404 YP_003069335.1 CDS METDI3847 NC_012988.1 3780338 3781180 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3780338..3781180 Methylobacterium extorquens DM4 8195956 YP_003069336.1 CDS tgt NC_012988.1 3781177 3782328 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11751936, 1706703, 2170107, 7507921, 7893665, 89155457, 92165719, 9714557; Product type e : enzyme; Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme) 3781177..3782328 Methylobacterium extorquens DM4 8193405 YP_003069337.1 CDS METDI3849 NC_012988.1 3782352 3782609 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3782352..3782609) Methylobacterium extorquens DM4 8196184 YP_003069338.1 CDS METDI3850 NC_012988.1 3782811 3783878 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3782811..3783878) Methylobacterium extorquens DM4 8193406 YP_003069339.1 CDS METDI3851 NC_012988.1 3786035 3787369 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3786035..3787369 Methylobacterium extorquens DM4 8196237 YP_003069340.1 CDS METDI3852 NC_012988.1 3787469 3789007 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3787469..3789007 Methylobacterium extorquens DM4 8193408 YP_003069341.1 CDS METDI3853 NC_012988.1 3789130 3789636 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3789130..3789636 Methylobacterium extorquens DM4 8193409 YP_003069342.1 CDS METDI3854 NC_012988.1 3789646 3790527 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor complement(3789646..3790527) Methylobacterium extorquens DM4 8193410 YP_003069343.1 CDS METDI3855 NC_012988.1 3790517 3790981 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3790517..3790981) Methylobacterium extorquens DM4 8193411 YP_003069344.1 CDS METDI3856 NC_012988.1 3791015 3791449 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3791015..3791449) Methylobacterium extorquens DM4 8193412 YP_003069345.1 CDS cyaA NC_012988.1 3791644 3793371 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Adenylate/guanylate cyclase 3791644..3793371 Methylobacterium extorquens DM4 8193413 YP_003069346.1 CDS METDI3858 NC_012988.1 3793380 3794201 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1368608, 15213385, 7704276; Product type e : enzyme; arylesterase (alpha/beta hydrolase fold), putative haloperoxidase complement(3793380..3794201) Methylobacterium extorquens DM4 8195233 YP_003069347.1 CDS METDI3859 NC_012988.1 3794270 3795457 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15188393, 16926146; hypothetical protein complement(3794270..3795457) Methylobacterium extorquens DM4 8193414 YP_003069348.1 CDS METDI3860 NC_012988.1 3795548 3796390 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3795548..3796390) Methylobacterium extorquens DM4 8193415 YP_003069349.1 CDS METDI3861 NC_012988.1 3796397 3796642 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3796397..3796642) Methylobacterium extorquens DM4 8193416 YP_003069350.1 CDS METDI3862 NC_012988.1 3796844 3797086 D Evidence 6 : Doubtful CDS; hypothetical protein 3796844..3797086 Methylobacterium extorquens DM4 8193417 YP_003069351.1 CDS hppA NC_012988.1 3797166 3799298 R pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase complement(3797166..3799298) Methylobacterium extorquens DM4 8193418 YP_003069352.1 CDS METDI3864 NC_012988.1 3799586 3799834 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3799586..3799834 Methylobacterium extorquens DM4 8195573 YP_003069353.1 CDS METDI3865 NC_012988.1 3800125 3800472 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3800125..3800472) Methylobacterium extorquens DM4 8193419 YP_003069354.1 CDS METDI3866 NC_012988.1 3800685 3800900 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3800685..3800900) Methylobacterium extorquens DM4 8193420 YP_003069355.1 CDS METDI3867 NC_012988.1 3801108 3802328 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; aminotransferase complement(3801108..3802328) Methylobacterium extorquens DM4 8193421 YP_003069356.1 CDS METDI3868 NC_012988.1 3802474 3802839 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3802474..3802839) Methylobacterium extorquens DM4 8193422 YP_003069357.1 CDS phaC NC_012988.1 3802967 3804784 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 7763712; Product type e : enzyme; Poly(3-hydroxyalkanoate) polymerase (PHA polymerase) (PHA synthase) (Polyhydroxyalkanoic acid synthase) 3802967..3804784 Methylobacterium extorquens DM4 8193423 YP_003069358.1 CDS METDI3870 NC_012988.1 3804910 3806727 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative monovalent cation:proton antiporter (CPA2 family) ybaL 3804910..3806727 Methylobacterium extorquens DM4 8195856 YP_003069359.1 CDS METDI3871 NC_012988.1 3806740 3807867 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Regulatory protein, LuxR complement(3806740..3807867) Methylobacterium extorquens DM4 8193424 YP_003069360.1 CDS glyS NC_012988.1 3808182 3810272 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glycine tRNA synthetase, beta subunit complement(3808182..3810272) Methylobacterium extorquens DM4 8193425 YP_003069361.1 CDS METDI3873 NC_012988.1 3810428 3812314 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3810428..3812314) Methylobacterium extorquens DM4 8195521 YP_003069362.1 CDS METDI3874 NC_012988.1 3812509 3812952 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3812509..3812952) Methylobacterium extorquens DM4 8193426 YP_003069363.1 CDS glyQ NC_012988.1 3812954 3813892 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(3812954..3813892) Methylobacterium extorquens DM4 8193427 YP_003069364.1 CDS METDI3876 NC_012988.1 3813988 3814170 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3813988..3814170) Methylobacterium extorquens DM4 8195520 YP_003069365.1 CDS METDI3877 NC_012988.1 3814397 3814639 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3814397..3814639 Methylobacterium extorquens DM4 8193428 YP_003069366.1 CDS METDI3878 NC_012988.1 3814652 3815215 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, TetR family complement(3814652..3815215) Methylobacterium extorquens DM4 8193429 YP_003069367.1 CDS METDI3879 NC_012988.1 3815219 3815683 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3815219..3815683) Methylobacterium extorquens DM4 8193430 YP_003069368.1 CDS METDI3880 NC_012988.1 3815968 3816978 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3815968..3816978 Methylobacterium extorquens DM4 8193431 YP_003069369.1 CDS sohB NC_012988.1 3817094 3817954 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; protease SohB, belong to MEROPS peptidase family S49 (protease IV family, clan S-) complement(3817094..3817954) Methylobacterium extorquens DM4 8193432 YP_003069370.1 CDS METDI3882 NC_012988.1 3818179 3818931 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase small complement(3818179..3818931) Methylobacterium extorquens DM4 8196121 YP_003069371.1 CDS METDI3883 NC_012988.1 3818932 3819159 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3818932..3819159) Methylobacterium extorquens DM4 8193433 YP_003069372.1 CDS ispB NC_012988.1 3819354 3820376 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2670911, 8037730, 8312607, 94311902, 97284515; Product type e : enzyme; octaprenyl diphosphate synthase 3819354..3820376 Methylobacterium extorquens DM4 8193434 YP_003069373.1 CDS ispE NC_012988.1 3820398 3821273 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(3820398..3821273) Methylobacterium extorquens DM4 8195607 YP_003069374.1 CDS METDI3887 NC_012988.1 3822284 3822709 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) 3822284..3822709 Methylobacterium extorquens DM4 8193435 YP_003069375.1 CDS METDI3888 NC_012988.1 3822484 3823038 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) 3822484..3823038 Methylobacterium extorquens DM4 8193436 YP_003069376.1 CDS METDI3890 NC_012988.1 3824383 3824565 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3824383..3824565) Methylobacterium extorquens DM4 8193438 YP_003069377.1 CDS METDI3891 NC_012988.1 3824825 3826720 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3824825..3826720) Methylobacterium extorquens DM4 8193439 YP_003069378.1 CDS METDI3892 NC_012988.1 3826853 3827149 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3826853..3827149) Methylobacterium extorquens DM4 8193440 YP_003069379.1 CDS METDI3893 NC_012988.1 3827221 3827433 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3827221..3827433) Methylobacterium extorquens DM4 8193441 YP_003069380.1 CDS METDI3894 NC_012988.1 3827840 3828079 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3827840..3828079 Methylobacterium extorquens DM4 8193442 YP_003069381.1 CDS METDI3895 NC_012988.1 3828226 3828549 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3828226..3828549 Methylobacterium extorquens DM4 8193443 YP_003069382.1 CDS METDI3899 NC_012988.1 3830100 3831068 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative integral membrane protein, putative Band 7 protein 3830100..3831068 Methylobacterium extorquens DM4 8193446 YP_003069383.1 CDS METDI3900 NC_012988.1 3831281 3832951 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused permease and ATPase subunits 3831281..3832951 Methylobacterium extorquens DM4 8193447 YP_003069384.1 CDS METDI3901 NC_012988.1 3833057 3833332 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3833057..3833332 Methylobacterium extorquens DM4 8193448 YP_003069385.1 CDS METDI3902 NC_012988.1 3833329 3833730 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3833329..3833730 Methylobacterium extorquens DM4 8193449 YP_003069386.1 CDS parE NC_012988.1 3833798 3835855 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3833798..3835855) Methylobacterium extorquens DM4 8193450 YP_003069387.1 CDS METDI3904 NC_012988.1 3836209 3836400 D Evidence 6 : Doubtful CDS; hypothetical protein 3836209..3836400 Methylobacterium extorquens DM4 8195829 YP_003069388.1 CDS ltaE NC_012988.1 3836424 3837464 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9464392; Product type e : enzyme; Low-specificity L-threonine aldolase (Low-specificity L-TA) complement(3836424..3837464) Methylobacterium extorquens DM4 8193451 YP_003069389.1 CDS METDI3906 NC_012988.1 3837606 3839372 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused ATPase and permease domains complement(3837606..3839372) Methylobacterium extorquens DM4 8195655 YP_003069390.1 CDS METDI3907 NC_012988.1 3839578 3840933 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Major facilitator superfamily MFS_1 complement(3839578..3840933) Methylobacterium extorquens DM4 8193452 YP_003069391.1 CDS METDI3908 NC_012988.1 3840930 3841712 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3840930..3841712) Methylobacterium extorquens DM4 8193453 YP_003069392.1 CDS METDI3909 NC_012988.1 3841917 3842291 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3841917..3842291 Methylobacterium extorquens DM4 8193454 YP_003069393.1 CDS METDI3910 NC_012988.1 3842327 3842767 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3842327..3842767) Methylobacterium extorquens DM4 8193455 YP_003069394.1 CDS METDI3911 NC_012988.1 3843088 3843420 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3843088..3843420 Methylobacterium extorquens DM4 8193456 YP_003069395.1 CDS METDI3912 NC_012988.1 3843510 3844301 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Short-chain dehydrogenase/reductase SDR complement(3843510..3844301) Methylobacterium extorquens DM4 8193457 YP_003069396.1 CDS METDI3913 NC_012988.1 3844384 3845763 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator superfamily complement(3844384..3845763) Methylobacterium extorquens DM4 8193458 YP_003069397.1 CDS METDI3914 NC_012988.1 3845992 3847011 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8344527; Product type pe : putative enzyme; putative alpha/beta hydrolase precursor 3845992..3847011 Methylobacterium extorquens DM4 8193459 YP_003069398.1 CDS METDI3915 NC_012988.1 3847094 3847960 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15188393, 16926146, 9772162; Product type pe : putative enzyme; putative NAD-binding dehydrogenase, putative 2-hydroxy-3-oxopropionate reductase 3847094..3847960 Methylobacterium extorquens DM4 8193460 YP_003069399.1 CDS METDI3916 NC_012988.1 3847964 3848671 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(3847964..3848671) Methylobacterium extorquens DM4 8193461 YP_003069400.1 CDS METDI3917 NC_012988.1 3848945 3849160 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3848945..3849160 Methylobacterium extorquens DM4 8193462 YP_003069401.1 CDS METDI3918 NC_012988.1 3849317 3849628 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NADH dehydrogenase (ubiquinone) Fe-S protein 4 (18kD) (NADH-coenzyme Q reductase) (nduFs4) (partial) 3849317..3849628 Methylobacterium extorquens DM4 8196252 YP_003069402.1 CDS guaD NC_012988.1 3849694 3850155 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11101664, 15180998; Product type e : enzyme; Guanine deaminase (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH) (GDEase) complement(3849694..3850155) Methylobacterium extorquens DM4 8193464 YP_003069403.1 CDS METDI3920 NC_012988.1 3850170 3851234 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3850170..3851234) Methylobacterium extorquens DM4 8195542 YP_003069404.1 CDS METDI3921 NC_012988.1 3851294 3852085 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3851294..3852085) Methylobacterium extorquens DM4 8193465 YP_003069405.1 CDS glgX NC_012988.1 3852312 3854588 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2975249; Product type e : enzyme; glycogen debranching enzyme 3852312..3854588 Methylobacterium extorquens DM4 8193466 YP_003069406.1 CDS METDI3923 NC_012988.1 3854761 3856362 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; histidine kinase 3854761..3856362 Methylobacterium extorquens DM4 8195493 YP_003069407.1 CDS icd NC_012988.1 3856759 3857973 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(3856759..3857973) Methylobacterium extorquens DM4 8193467 YP_003069408.1 CDS METDI3926 NC_012988.1 3858118 3858630 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3858118..3858630) Methylobacterium extorquens DM4 8195588 YP_003069409.1 CDS fae NC_012988.1 3858813 3859361 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; formaldehyde activating enzyme homolog 3858813..3859361 Methylobacterium extorquens DM4 8193468 YP_003069410.1 CDS METDI3928 NC_012988.1 3859468 3859728 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pcp : putative cell process; putative addiction module antidote protein, CopG/Arc/MetJ family 3859468..3859728 Methylobacterium extorquens DM4 8195355 YP_003069411.1 CDS METDI3930 NC_012988.1 3859855 3860409 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) complement(3859855..3860409) Methylobacterium extorquens DM4 8193470 YP_003069412.1 CDS METDI3931 NC_012988.1 3860184 3860609 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) complement(3860184..3860609) Methylobacterium extorquens DM4 8193471 YP_003069413.1 CDS METDI3932 NC_012988.1 3860887 3861624 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; tRNA/rRNA methyltransferase 3860887..3861624 Methylobacterium extorquens DM4 8193472 YP_003069414.1 CDS METDI3933 NC_012988.1 3861628 3861969 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3861628..3861969) Methylobacterium extorquens DM4 8193473 YP_003069415.1 CDS METDI3934 NC_012988.1 3861999 3863012 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1735726; Product type pe : putative enzyme; putative alcohol dehydrogenase complement(3861999..3863012) Methylobacterium extorquens DM4 8193474 YP_003069416.1 CDS METDI3935 NC_012988.1 3863145 3864830 R Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; methyl-accepting chemotaxis receptor transducer precursor complement(3863145..3864830) Methylobacterium extorquens DM4 8193475 YP_003069417.1 CDS METDI3936 NC_012988.1 3865328 3865876 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3865328..3865876) Methylobacterium extorquens DM4 8193476 YP_003069418.1 CDS metY-4 NC_012988.1 3865884 3867191 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11566369, 12951250; Product type e : enzyme; trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase) complement(3865884..3867191) Methylobacterium extorquens DM4 8193477 YP_003069419.1 CDS METDI3938 NC_012988.1 3867335 3867721 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) complement(3867335..3867721) Methylobacterium extorquens DM4 8195691 YP_003069420.1 CDS glcF NC_012988.1 3867835 3869232 R Evidence 2b : Function of strongly homologous gene; Product type c : carrier; glycolate oxidase iron-sulfur subunit complement(3867835..3869232) Methylobacterium extorquens DM4 8193478 YP_003069421.1 CDS METDI3940 NC_012988.1 3869388 3869756 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3869388..3869756) Methylobacterium extorquens DM4 8195487 YP_003069422.1 CDS METDI3941 NC_012988.1 3869964 3870914 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative lipase/esterase 3869964..3870914 Methylobacterium extorquens DM4 8193479 YP_003069423.1 CDS METDI3942 NC_012988.1 3870954 3873464 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ATP-dependent DNA helicase 3870954..3873464 Methylobacterium extorquens DM4 8193480 YP_003069424.1 CDS METDI3943 NC_012988.1 3873506 3874219 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3873506..3874219 Methylobacterium extorquens DM4 8193481 YP_003069425.1 CDS METDI3944 NC_012988.1 3874333 3874770 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3874333..3874770) Methylobacterium extorquens DM4 8193482 YP_003069426.1 CDS METDI3945 NC_012988.1 3875072 3876397 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative chloride channel protein 3875072..3876397 Methylobacterium extorquens DM4 8193483 YP_003069427.1 CDS METDI3946 NC_012988.1 3876471 3876650 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3876471..3876650 Methylobacterium extorquens DM4 8193484 YP_003069428.1 CDS METDI3947 NC_012988.1 3876666 3877511 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 3876666..3877511 Methylobacterium extorquens DM4 8193485 YP_003069429.1 CDS thiL NC_012988.1 3877626 3878603 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; thiamin-monophosphate kinase complement(3877626..3878603) Methylobacterium extorquens DM4 8193486 YP_003069430.1 CDS nusB NC_012988.1 3878609 3879124 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275; Product type f : factor; transcription antitermination factor complement(3878609..3879124) Methylobacterium extorquens DM4 8196190 YP_003069431.1 CDS ribE NC_012988.1 3879121 3879642 R Evidence 2b : Function of strongly homologous gene; PubMedId : 14704707; Product type e : enzyme; 6,7-dimethyl-8-ribityllumazine synthase (DMRL synthase) (Lumazine synthase) (Riboflavin synthase beta chain) complement(3879121..3879642) Methylobacterium extorquens DM4 8195802 YP_003069432.1 CDS METDI3951 NC_012988.1 3879954 3881480 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3879954..3881480 Methylobacterium extorquens DM4 8195994 YP_003069433.1 CDS METDI3952 NC_012988.1 3881480 3881905 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative GtrA-like protein 3881480..3881905 Methylobacterium extorquens DM4 8193487 YP_003069434.1 CDS METDI3953 NC_012988.1 3881893 3883113 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3881893..3883113) Methylobacterium extorquens DM4 8193488 YP_003069435.1 CDS METDI3954 NC_012988.1 3883407 3883928 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3883407..3883928 Methylobacterium extorquens DM4 8193489 YP_003069436.1 CDS ribE NC_012988.1 3883942 3884580 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; riboflavin synthase, alpha subunit complement(3883942..3884580) Methylobacterium extorquens DM4 8193490 YP_003069437.1 CDS ribD NC_012988.1 3884582 3885712 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino) uracil reductase complement(3884582..3885712) Methylobacterium extorquens DM4 8195995 YP_003069438.1 CDS nrdR NC_012988.1 3885709 3886266 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator NrdR complement(3885709..3886266) Methylobacterium extorquens DM4 8195993 YP_003069439.1 CDS METDI3958 NC_012988.1 3886348 3886800 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Rrf2 family complement(3886348..3886800) Methylobacterium extorquens DM4 8193491 YP_003069440.1 CDS glyA NC_012988.1 3887054 3888358 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(3887054..3888358) Methylobacterium extorquens DM4 8193492 YP_003069441.1 CDS METDI3960 NC_012988.1 3888725 3889213 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative F0F1 ATP synthase, subunit b (atpF) complement(3888725..3889213) Methylobacterium extorquens DM4 8195519 YP_003069442.1 CDS METDI3961 NC_012988.1 3889301 3889906 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative F0F1 ATP synthase, subunit b (atpF) complement(3889301..3889906) Methylobacterium extorquens DM4 8193493 YP_003069443.1 CDS atpE NC_012988.1 3890104 3890331 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ATP synthase F0 sector subunit c complement(3890104..3890331) Methylobacterium extorquens DM4 8193494 YP_003069444.1 CDS atpB NC_012988.1 3890392 3891147 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(3890392..3891147) Methylobacterium extorquens DM4 8195120 YP_003069445.1 CDS METDI3964 NC_012988.1 3891268 3891636 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative FoF1 ATP synthase, subunit I (atpI) complement(3891268..3891636) Methylobacterium extorquens DM4 8195117 YP_003069446.1 CDS METDI3965 NC_012988.1 3891800 3892453 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(3891800..3892453) Methylobacterium extorquens DM4 8193495 YP_003069447.1 CDS METDI3966 NC_012988.1 3892728 3893204 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3892728..3893204) Methylobacterium extorquens DM4 8193496 YP_003069448.1 CDS mutY NC_012988.1 3893374 3894588 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14961129; Product type e : enzyme; A/G-specific adenine glycosylase 3893374..3894588 Methylobacterium extorquens DM4 8193497 YP_003069449.1 CDS ccrfM NC_012988.1 3894652 3895848 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11325934; Product type e : enzyme; site-specific DNA-methyltransferase (adenine-specific) complement(3894652..3895848) Methylobacterium extorquens DM4 8195747 YP_003069450.1 CDS METDI3969 NC_012988.1 3896278 3896625 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative rare lipoprotein A precursor 3896278..3896625 Methylobacterium extorquens DM4 8195158 YP_003069451.1 CDS METDI3970 NC_012988.1 3896753 3897070 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3896753..3897070 Methylobacterium extorquens DM4 8193498 YP_003069452.1 CDS METDI3972 NC_012988.1 3897573 3899396 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-binding protein with two ATPase domains, ABC transporter related 3897573..3899396 Methylobacterium extorquens DM4 8193500 YP_003069453.1 CDS METDI3973 NC_012988.1 3899723 3901384 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1370281; Product type pt : putative transporter; putative porin precursor ; putative exported protein 3899723..3901384 Methylobacterium extorquens DM4 8193501 YP_003069454.1 CDS METDI3974 NC_012988.1 3901599 3903605 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3901599..3903605 Methylobacterium extorquens DM4 8193502 YP_003069455.1 CDS METDI3975 NC_012988.1 3903589 3904845 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative adenylate cyclase protein complement(3903589..3904845) Methylobacterium extorquens DM4 8193503 YP_003069456.1 CDS METDI3976 NC_012988.1 3904986 3905591 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3904986..3905591 Methylobacterium extorquens DM4 8193504 YP_003069457.1 CDS METDI3977 NC_012988.1 3905615 3907939 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative soluble lytic murein transglycosylase precursor complement(3905615..3907939) Methylobacterium extorquens DM4 8193505 YP_003069458.1 CDS dapA NC_012988.1 3908139 3909029 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3908139..3909029 Methylobacterium extorquens DM4 8193506 YP_003069459.1 CDS smpB NC_012988.1 3909132 3909605 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3909132..3909605 Methylobacterium extorquens DM4 8195270 YP_003069460.1 CDS METDI3980 NC_012988.1 3909827 3910483 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3909827..3910483) Methylobacterium extorquens DM4 8196118 YP_003069461.1 CDS METDI3981 NC_012988.1 3910521 3910748 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3910521..3910748) Methylobacterium extorquens DM4 8193507 YP_003069462.1 CDS pyrE NC_012988.1 3910984 3911574 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8787418; Product type e : enzyme; orotate phosphoribosyltransferase (OPRT) (OPRTase) complement(3910984..3911574) Methylobacterium extorquens DM4 8193508 YP_003069463.1 CDS METDI3983 NC_012988.1 3911790 3912137 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3911790..3912137) Methylobacterium extorquens DM4 8195950 YP_003069464.1 CDS METDI3984 NC_012988.1 3911916 3912182 D Evidence 6 : Doubtful CDS; hypothetical protein 3911916..3912182 Methylobacterium extorquens DM4 8193509 YP_003069465.1 CDS relA NC_012988.1 3912252 3914483 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; GTP pyrophosphokinase complement(3912252..3914483) Methylobacterium extorquens DM4 8193510 YP_003069466.1 CDS rpoZ NC_012988.1 3914855 3915265 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(3914855..3915265) Methylobacterium extorquens DM4 8195978 YP_003069467.1 CDS METDI3987 NC_012988.1 3915469 3916035 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12886008, 16926146; Product type cp : cell process; NifU-like 3915469..3916035 Methylobacterium extorquens DM4 8196051 YP_003069468.1 CDS METDI3988 NC_012988.1 3916193 3916873 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Peptidase M22, glycoprotease 3916193..3916873 Methylobacterium extorquens DM4 8193511 YP_003069469.1 CDS rimI NC_012988.1 3916870 3917391 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2828880; Product type e : enzyme; Ribosomal-protein-alanine N-acetyltransferase 3916870..3917391 Methylobacterium extorquens DM4 8193512 YP_003069470.1 CDS METDI3990 NC_012988.1 3917417 3918295 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16151217; Product type pe : putative enzyme; putative 1-acylglycerol-3-phosphate O-acyltransferase (plsC) 3917417..3918295 Methylobacterium extorquens DM4 8195997 YP_003069471.1 CDS METDI3991 NC_012988.1 3918300 3918740 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3918300..3918740) Methylobacterium extorquens DM4 8193513 YP_003069472.1 CDS miaB NC_012988.1 3918873 3920213 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 3918873..3920213 Methylobacterium extorquens DM4 8193514 YP_003069473.1 CDS ybeZ NC_012988.1 3920250 3921356 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enzyme with nucleoside triphosphate hydrolase domain 3920250..3921356 Methylobacterium extorquens DM4 8195695 YP_003069474.1 CDS METDI3994 NC_012988.1 3921427 3921912 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9623911; Product type pe : putative enzyme; putative metalloprotease 3921427..3921912 Methylobacterium extorquens DM4 8196349 YP_003069475.1 CDS METDI3995 NC_012988.1 3921949 3923097 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative HlyC/CorC family of transporters with CBS domains 3921949..3923097 Methylobacterium extorquens DM4 8193515 YP_003069476.1 CDS lnt NC_012988.1 3923126 3924829 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 3923126..3924829 Methylobacterium extorquens DM4 8193516 YP_003069477.1 CDS METDI3997 NC_012988.1 3925012 3925785 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3925012..3925785 Methylobacterium extorquens DM4 8195640 YP_003069478.1 CDS katA NC_012988.1 3925896 3927488 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1860824; Product type e : enzyme; catalase (hydroperoxidase II) complement(3925896..3927488) Methylobacterium extorquens DM4 8193517 YP_003069479.1 CDS oxyR NC_012988.1 3927636 3928607 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9190810, 9809430; Product type r : regulator; oxidative stress transcriptional regulator, LysR family 3927636..3928607 Methylobacterium extorquens DM4 8195613 YP_003069480.1 CDS METDI4000 NC_012988.1 3928761 3929816 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transport protein (abrB-like) 3928761..3929816 Methylobacterium extorquens DM4 8195821 YP_003069481.1 CDS METDI4001 NC_012988.1 3929780 3930157 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diacylglycerol kinase (dgkA-like) 3929780..3930157 Methylobacterium extorquens DM4 8193518 YP_003069482.1 CDS METDI4002 NC_012988.1 3930180 3930377 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3930180..3930377) Methylobacterium extorquens DM4 8193519 YP_003069483.1 CDS METDI4003 NC_012988.1 3930374 3930574 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3930374..3930574) Methylobacterium extorquens DM4 8193520 YP_003069484.1 CDS METDI4004 NC_012988.1 3930849 3931406 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3930849..3931406 Methylobacterium extorquens DM4 8193521 YP_003069485.1 CDS murI NC_012988.1 3931416 3932291 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1355768, 8098327; Product type e : enzyme; glutamate racemase complement(3931416..3932291) Methylobacterium extorquens DM4 8193522 YP_003069486.1 CDS METDI4006 NC_012988.1 3932502 3933764 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3932502..3933764 Methylobacterium extorquens DM4 8195743 YP_003069487.1 CDS METDI4007 NC_012988.1 3933822 3934799 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3933822..3934799 Methylobacterium extorquens DM4 8193523 YP_003069488.1 CDS METDI4008 NC_012988.1 3935076 3937217 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15033235; Product type pe : putative enzyme; hypothetical protein 3935076..3937217 Methylobacterium extorquens DM4 8193524 YP_003069489.1 CDS METDI4009 NC_012988.1 3937267 3937707 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3937267..3937707) Methylobacterium extorquens DM4 8193525 YP_003069490.1 CDS nasA NC_012988.1 3937930 3940617 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8468296; Product type e : enzyme; nitrate reductase, large subunit 3937930..3940617 Methylobacterium extorquens DM4 8193526 YP_003069491.1 CDS cysG NC_012988.1 3940805 3942262 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Siroheme synthase 3940805..3942262 Methylobacterium extorquens DM4 8195772 YP_003069492.1 CDS METDI4012 NC_012988.1 3942548 3943150 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; Electron transport protein SenC-related 3942548..3943150 Methylobacterium extorquens DM4 8195253 YP_003069493.1 CDS METDI4013 NC_012988.1 3943101 3944945 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyltransferase, putative membrane protein complement(3943101..3944945) Methylobacterium extorquens DM4 8193527 YP_003069494.1 CDS METDI4014 NC_012988.1 3945306 3945989 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic amino acid-binding protein 3945306..3945989 Methylobacterium extorquens DM4 8193528 YP_003069495.1 CDS METDI4015 NC_012988.1 3946085 3946291 D Evidence 6 : Doubtful CDS; hypothetical protein 3946085..3946291 Methylobacterium extorquens DM4 8193529 YP_003069496.1 CDS METDI4016 NC_012988.1 3946315 3946725 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3946315..3946725) Methylobacterium extorquens DM4 8193530 YP_003069497.1 CDS cobT NC_012988.1 3946819 3948726 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1429466, 1917840; Product type e : enzyme; Cobaltochelatase (cobT protein) complement(3946819..3948726) Methylobacterium extorquens DM4 8193531 YP_003069498.1 CDS cobS NC_012988.1 3948847 3949830 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1429466, 1917840; Product type e : enzyme; Cobaltochelatase (cobS protein) complement(3948847..3949830) Methylobacterium extorquens DM4 8195199 YP_003069499.1 CDS METDI4019 NC_012988.1 3950006 3950176 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3950006..3950176) Methylobacterium extorquens DM4 8195197 YP_003069500.1 CDS METDI4020 NC_012988.1 3950170 3950877 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative chaperone protein, DnaJ domain complement(3950170..3950877) Methylobacterium extorquens DM4 8193532 YP_003069501.1 CDS METDI4021 NC_012988.1 3951045 3951323 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; BolA-like protein 3951045..3951323 Methylobacterium extorquens DM4 8193533 YP_003069502.1 CDS METDI4022 NC_012988.1 3951355 3951777 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Class I peptide chain release factor domain 3951355..3951777 Methylobacterium extorquens DM4 8193534 YP_003069503.1 CDS METDI4023 NC_012988.1 3951791 3952486 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3951791..3952486) Methylobacterium extorquens DM4 8193535 YP_003069504.1 CDS METDI4024 NC_012988.1 3952585 3953580 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3952585..3953580) Methylobacterium extorquens DM4 8193536 YP_003069505.1 CDS METDI4025 NC_012988.1 3953626 3954684 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3953626..3954684 Methylobacterium extorquens DM4 8193537 YP_003069506.1 CDS METDI4026 NC_012988.1 3954681 3956525 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-dependent DNA ligase 3954681..3956525 Methylobacterium extorquens DM4 8193538 YP_003069507.1 CDS METDI4027 NC_012988.1 3956585 3957052 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3956585..3957052 Methylobacterium extorquens DM4 8193539 YP_003069508.1 CDS METDI4028 NC_012988.1 3958002 3958160 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3958002..3958160 Methylobacterium extorquens DM4 8193540 YP_003069509.1 CDS METDI4029 NC_012988.1 3958169 3958615 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3958169..3958615) Methylobacterium extorquens DM4 8193541 YP_003069510.1 CDS METDI4030 NC_012988.1 3958738 3958902 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3958738..3958902) Methylobacterium extorquens DM4 8193542 YP_003069511.1 CDS METDI4031 NC_012988.1 3959005 3961206 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12535077; Product type pe : putative enzyme; putative fatty acid oxidation complex subunit alpha (enoyl-CoA hydratase and epimerase and isomerase ; 3-hydroxyacyl-CoA dehydrogenase) (fadJ-like; synonym yfcX) complement(3959005..3961206) Methylobacterium extorquens DM4 8193543 YP_003069512.1 CDS METDI4032 NC_012988.1 3961328 3962125 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3961328..3962125 Methylobacterium extorquens DM4 8193544 YP_003069513.1 CDS METDI4033 NC_012988.1 3962201 3962698 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3962201..3962698) Methylobacterium extorquens DM4 8193545 YP_003069514.1 CDS METDI4034 NC_012988.1 3962826 3964034 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(3962826..3964034) Methylobacterium extorquens DM4 8193546 YP_003069515.1 CDS fadE NC_012988.1 3964221 3966011 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12039753; Product type e : enzyme; acyl-CoA dehydrogenase complement(3964221..3966011) Methylobacterium extorquens DM4 8193547 YP_003069516.1 CDS METDI4036 NC_012988.1 3966322 3969645 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3966322..3969645 Methylobacterium extorquens DM4 8195352 YP_003069517.1 CDS METDI4037 NC_012988.1 3970096 3970422 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3970096..3970422 Methylobacterium extorquens DM4 8193548 YP_003069518.1 CDS METDI4038 NC_012988.1 3970480 3971424 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3970480..3971424) Methylobacterium extorquens DM4 8193549 YP_003069519.1 CDS METDI4039 NC_012988.1 3971562 3972080 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3971562..3972080 Methylobacterium extorquens DM4 8193550 YP_003069520.1 CDS METDI4040 NC_012988.1 3972077 3972880 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3972077..3972880 Methylobacterium extorquens DM4 8193551 YP_003069521.1 CDS METDI4042 NC_012988.1 3972936 3974243 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8472911; Product type pe : putative enzyme; putative oxidoreductase precursor (tat pathway signal) 3972936..3974243 Methylobacterium extorquens DM4 8193552 YP_003069522.1 CDS METDI4043 NC_012988.1 3974355 3974501 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3974355..3974501) Methylobacterium extorquens DM4 8193553 YP_003069523.1 CDS METDI4044 NC_012988.1 3974582 3975877 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative protease complement(3974582..3975877) Methylobacterium extorquens DM4 8193554 YP_003069524.1 CDS thrC NC_012988.1 3976099 3977511 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1333566; Product type e : enzyme; threonine synthase complement(3976099..3977511) Methylobacterium extorquens DM4 8193555 YP_003069525.1 CDS METDI4046 NC_012988.1 3977597 3978010 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3977597..3978010) Methylobacterium extorquens DM4 8196194 YP_003069526.1 CDS METDI4047 NC_012988.1 3978108 3978869 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10622737; Product type pm : putative membrane component; putative surfeit locus 1 family protein (surf1-like) complement(3978108..3978869) Methylobacterium extorquens DM4 8193556 YP_003069527.1 CDS METDI4048 NC_012988.1 3978878 3979252 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3978878..3979252) Methylobacterium extorquens DM4 8193557 YP_003069528.1 CDS coxC NC_012988.1 3979379 3980236 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7651515; Product type e : enzyme; cytochrome c oxidase subunit III complement(3979379..3980236) Methylobacterium extorquens DM4 8193558 YP_003069529.1 CDS METDI4050 NC_012988.1 3980383 3980991 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative cytochrome-c oxidase assembly protein (coxG) complement(3980383..3980991) Methylobacterium extorquens DM4 8195207 YP_003069530.1 CDS METDI4051 NC_012988.1 3981004 3981180 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative CoxF complement(3981004..3981180) Methylobacterium extorquens DM4 8193559 YP_003069531.1 CDS coxE NC_012988.1 3981177 3982130 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(3981177..3982130) Methylobacterium extorquens DM4 8193560 YP_003069532.1 CDS coxA NC_012988.1 3982296 3983924 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9380672; Product type e : enzyme; cytochrome c oxidase subunit I complement(3982296..3983924) Methylobacterium extorquens DM4 8195208 YP_003069533.1 CDS coxB NC_012988.1 3984002 3984841 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; cytochrome c oxidase subunit II complement(3984002..3984841) Methylobacterium extorquens DM4 8195205 YP_003069534.1 CDS METDI4055 NC_012988.1 3985097 3985972 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative formate dehydrogenase accesory protein 3985097..3985972 Methylobacterium extorquens DM4 8195206 YP_003069535.1 CDS METDI4056 NC_012988.1 3986000 3987025 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3986000..3987025) Methylobacterium extorquens DM4 8193561 YP_003069536.1 CDS gltB NC_012988.1 3987662 3992380 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7727752; Product type e : enzyme; glutamate synthase, large subunit 3987662..3992380 Methylobacterium extorquens DM4 8193562 YP_003069537.1 CDS gltD NC_012988.1 3992504 3993937 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3992504..3993937 Methylobacterium extorquens DM4 8195512 YP_003069538.1 CDS METDI4059 NC_012988.1 3994211 3994801 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3994211..3994801 Methylobacterium extorquens DM4 8195513 YP_003069539.1 CDS METDI4060 NC_012988.1 3994774 3995697 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase, beta-lactamase family protein complement(3994774..3995697) Methylobacterium extorquens DM4 8193563 YP_003069540.1 CDS METDI4061 NC_012988.1 3995876 3997216 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transmembrane histidine kinase; putative domains: HK dimerisation, ATPase 3995876..3997216 Methylobacterium extorquens DM4 8193564 YP_003069541.1 CDS METDI4062 NC_012988.1 3997222 3997884 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator; Input and output domains: CheY and HTH LuxR family 3997222..3997884 Methylobacterium extorquens DM4 8193565 YP_003069542.1 CDS METDI4063 NC_012988.1 3997912 3999363 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3997912..3999363) Methylobacterium extorquens DM4 8193566 YP_003069543.1 CDS METDI4064 NC_012988.1 3999634 4000815 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane bound lytic murein transglycosylase B, mltB complement(3999634..4000815) Methylobacterium extorquens DM4 8193567 YP_003069544.1 CDS galE NC_012988.1 4000812 4001804 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; UDP-galactose 4-epimerase complement(4000812..4001804) Methylobacterium extorquens DM4 8193568 YP_003069545.1 CDS galU NC_012988.1 4001977 4002843 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glucose-1-phosphate uridylyltransferase 4001977..4002843 Methylobacterium extorquens DM4 8195462 YP_003069546.1 CDS METDI4067 NC_012988.1 4003085 4003930 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; N-formylglutamate amidohydrolase (Beta-citryl-L-glutamate hydrolase) complement(4003085..4003930) Methylobacterium extorquens DM4 8195464 YP_003069547.1 CDS METDI4068 NC_012988.1 4004288 4004644 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver; CheY-like protein 4004288..4004644 Methylobacterium extorquens DM4 8193569 YP_003069548.1 CDS grxC NC_012988.1 4004871 4005128 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11031118, 7937896, 8636094, 94316500, 95024051, 99175138, 9973569; Product type c : carrier; glutaredoxin 3 4004871..4005128 Methylobacterium extorquens DM4 8193570 YP_003069549.1 CDS METDI4070 NC_012988.1 4005125 4005970 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 4005125..4005970 Methylobacterium extorquens DM4 8195536 YP_003069550.1 CDS METDI4071 NC_012988.1 4006091 4006567 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4006091..4006567 Methylobacterium extorquens DM4 8193571 YP_003069551.1 CDS METDI4072 NC_012988.1 4006587 4007651 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase; putative HK, ATPase and sensory PAS domain complement(4006587..4007651) Methylobacterium extorquens DM4 8193572 YP_003069552.1 CDS msrA NC_012988.1 4007827 4008486 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10964927, 11080639, 11677230, 1386361, 94156870, 7836279; Product type e : enzyme; Peptide methionine sulfoxide reductase msrA (Protein-methionine-S-oxide reductase) (Peptide Met(O) reductase) 4007827..4008486 Methylobacterium extorquens DM4 8193573 YP_003069553.1 CDS yqhA NC_012988.1 4008591 4009094 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 4008591..4009094 Methylobacterium extorquens DM4 8195728 YP_003069554.1 CDS mepA NC_012988.1 4009102 4010031 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(4009102..4010031) Methylobacterium extorquens DM4 8196377 YP_003069555.1 CDS METDI4076 NC_012988.1 4010158 4010553 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4010158..4010553 Methylobacterium extorquens DM4 8195679 YP_003069556.1 CDS METDI4077 NC_012988.1 4010584 4010931 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4010584..4010931) Methylobacterium extorquens DM4 8193574 YP_003069557.1 CDS nhaA NC_012988.1 4011017 4012258 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 91250446, 92283803, 93131914; Product type t : transporter; sodium:proton antiporter (NhaA family) complement(4011017..4012258) Methylobacterium extorquens DM4 8193575 YP_003069558.1 CDS METDI4079 NC_012988.1 4012330 4012971 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Redoxin domain protein complement(4012330..4012971) Methylobacterium extorquens DM4 8195777 YP_003069559.1 CDS argH NC_012988.1 4013011 4014402 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16201833; Product type e : enzyme; argininosuccinate lyase 4013011..4014402 Methylobacterium extorquens DM4 8193576 YP_003069560.1 CDS METDI4081 NC_012988.1 4014499 4014810 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4014499..4014810 Methylobacterium extorquens DM4 8195089 YP_003069561.1 CDS METDI4082 NC_012988.1 4014966 4015649 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4014966..4015649 Methylobacterium extorquens DM4 8193577 YP_003069562.1 CDS METDI4083 NC_012988.1 4015828 4016082 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4015828..4016082) Methylobacterium extorquens DM4 8193578 YP_003069563.1 CDS METDI4084 NC_012988.1 4016524 4017210 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase family hydrolase complement(4016524..4017210) Methylobacterium extorquens DM4 8193579 YP_003069564.1 CDS METDI4085 NC_012988.1 4017483 4019252 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carbamoyl transferase 4017483..4019252 Methylobacterium extorquens DM4 8193580 YP_003069565.1 CDS METDI4086 NC_012988.1 4019316 4019660 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4019316..4019660) Methylobacterium extorquens DM4 8193581 YP_003069566.1 CDS METDI4087 NC_012988.1 4019757 4020431 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1376111; Product type e : enzyme; haloacid dehalogenase, type II complement(4019757..4020431) Methylobacterium extorquens DM4 8193582 YP_003069567.1 CDS METDI4088 NC_012988.1 4020469 4022052 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 18832143; Product type m : membrane component; putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein complement(4020469..4022052) Methylobacterium extorquens DM4 8193583 YP_003069568.1 CDS sodB NC_012988.1 4022299 4022898 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10419947, 16926146; Product type e : enzyme; superoxide dismutase complement(4022299..4022898) Methylobacterium extorquens DM4 8193584 YP_003069569.1 CDS METDI4091 NC_012988.1 4023268 4024260 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4023268..4024260 Methylobacterium extorquens DM4 8196120 YP_003069570.1 CDS METDI4092 NC_012988.1 4024330 4026081 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase of the HWE family complement(4024330..4026081) Methylobacterium extorquens DM4 8193585 YP_003069571.1 CDS METDI4093 NC_012988.1 4026189 4027148 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15297914, 7517390; Product type pe : putative enzyme; putative glycosyl transferase complement(4026189..4027148) Methylobacterium extorquens DM4 8193586 YP_003069572.1 CDS METDI4094 NC_012988.1 4027145 4028050 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glycosyl transferase, family 2 complement(4027145..4028050) Methylobacterium extorquens DM4 8193587 YP_003069573.1 CDS METDI4095 NC_012988.1 4028123 4029625 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Peptidase complement(4028123..4029625) Methylobacterium extorquens DM4 8193588 YP_003069574.1 CDS METDI4096 NC_012988.1 4029632 4030483 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4029632..4030483) Methylobacterium extorquens DM4 8193589 YP_003069575.1 CDS METDI4097 NC_012988.1 4031202 4031624 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4031202..4031624 Methylobacterium extorquens DM4 8195035 YP_003069576.1 CDS metK NC_012988.1 4031832 4033007 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methionine adenosyltransferase 1 (AdoMet synthetase) 4031832..4033007 Methylobacterium extorquens DM4 8193591 YP_003069577.1 CDS trmB NC_012988.1 4033017 4033754 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; tRNA (guanine-N(7)-)-methyltransferase (tRNA(m7G46)-methyltransferase) 4033017..4033754 Methylobacterium extorquens DM4 8195685 YP_003069578.1 CDS TopA NC_012988.1 4034008 4036740 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(4034008..4036740) Methylobacterium extorquens DM4 8196210 YP_003069579.1 CDS METDI4101 NC_012988.1 4036889 4037848 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Sulfite oxidase, oxidoreductase molybdopterin binding complement(4036889..4037848) Methylobacterium extorquens DM4 8196206 YP_003069580.1 CDS METDI4102 NC_012988.1 4037845 4038717 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4037845..4038717) Methylobacterium extorquens DM4 8193592 YP_003069581.1 CDS METDI4103 NC_012988.1 4038882 4039193 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4038882..4039193) Methylobacterium extorquens DM4 8193593 YP_003069582.1 CDS pyrB NC_012988.1 4039468 4040415 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4039468..4040415 Methylobacterium extorquens DM4 8193594 YP_003069583.1 CDS pyrC NC_012988.1 4040421 4041725 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7516791, 7896697; Product type pe : putative enzyme; putative dihydroorotase-like protein 4040421..4041725 Methylobacterium extorquens DM4 8195946 YP_003069584.1 CDS METDI4106 NC_012988.1 4041722 4042330 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16949372; Product type pe : putative enzyme; putative 1-acyl glycerol-3-phosphate synthetase (PlsY) 4041722..4042330 Methylobacterium extorquens DM4 8195947 YP_003069585.1 CDS DprA NC_012988.1 4042362 4043555 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; DNA protecting protein DprA 4042362..4043555 Methylobacterium extorquens DM4 8193595 YP_003069586.1 CDS METDI4108 NC_012988.1 4043879 4044706 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4043879..4044706 Methylobacterium extorquens DM4 8195316 YP_003069587.1 CDS METDI4109 NC_012988.1 4044703 4045854 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4044703..4045854 Methylobacterium extorquens DM4 8193596 YP_003069588.1 CDS inh NC_012988.1 4045945 4046619 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12244065, 8626329, 8885414; Product type e : enzyme; isonitrile hydratase, ThiJ/PfpI family protein 4045945..4046619 Methylobacterium extorquens DM4 8193597 YP_003069589.1 CDS METDI4111 NC_012988.1 4046616 4047098 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10982859, 14512736; Product type pe : putative enzyme; putative Holliday junction resolvase complement(4046616..4047098) Methylobacterium extorquens DM4 8195601 YP_003069590.1 CDS METDI4112 NC_012988.1 4047110 4047688 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4047110..4047688) Methylobacterium extorquens DM4 8193598 YP_003069591.1 CDS METDI4113 NC_012988.1 4047849 4048034 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4047849..4048034 Methylobacterium extorquens DM4 8193599 YP_003069592.1 CDS gatC NC_012988.1 4048193 4048480 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C (Asp/Glu-ADT subunit C) 4048193..4048480 Methylobacterium extorquens DM4 8193600 YP_003069593.1 CDS gatA NC_012988.1 4048577 4050058 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 4048577..4050058 Methylobacterium extorquens DM4 8195471 YP_003069594.1 CDS METDI4116 NC_012988.1 4050055 4050360 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4050055..4050360 Methylobacterium extorquens DM4 8195468 YP_003069595.1 CDS METDI4118 NC_012988.1 4050881 4054045 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; multidrug efflux system protein (acrB ou acrF) complement(4050881..4054045) Methylobacterium extorquens DM4 8193602 YP_003069596.1 CDS METDI4119 NC_012988.1 4054124 4055449 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; putative RND efflux transporter, membrane fusion protein subunit complement(4054124..4055449) Methylobacterium extorquens DM4 8193603 YP_003069597.1 CDS METDI4120 NC_012988.1 4055830 4056258 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4055830..4056258) Methylobacterium extorquens DM4 8193604 YP_003069598.1 CDS METDI4121 NC_012988.1 4056492 4057091 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4056492..4057091 Methylobacterium extorquens DM4 8193605 YP_003069599.1 CDS METDI4122 NC_012988.1 4057319 4057639 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4057319..4057639 Methylobacterium extorquens DM4 8193606 YP_003069600.1 CDS metY-1 NC_012988.1 4057671 4058993 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11566369, 12951250; Product type e : enzyme; Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase) 4057671..4058993 Methylobacterium extorquens DM4 8193607 YP_003069601.1 CDS METDI4124 NC_012988.1 4058995 4060017 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2OG-Fe(II) oxygenase superfamily protein 4058995..4060017 Methylobacterium extorquens DM4 8195688 YP_003069602.1 CDS METDI4125 NC_012988.1 4060014 4060199 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4060014..4060199 Methylobacterium extorquens DM4 8193608 YP_003069603.1 CDS METDI4126 NC_012988.1 4060130 4060300 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4060130..4060300 Methylobacterium extorquens DM4 8193609 YP_003069604.1 CDS METDI4127 NC_012988.1 4060431 4060667 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4060431..4060667 Methylobacterium extorquens DM4 8193610 YP_003069605.1 CDS METDI4128 NC_012988.1 4060759 4061031 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Usg family protein complement(4060759..4061031) Methylobacterium extorquens DM4 8193611 YP_003069606.1 CDS groL NC_012988.1 4061414 4063036 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10619429, 12475168, 12653476, 1349729, 25784, 91129229, 91338746, 94171713; Product type f : factor; 60 kDa chaperonin (protein Cpn60, groEL protein) complement(4061414..4063036) Methylobacterium extorquens DM4 8193612 YP_003069607.1 CDS groS NC_012988.1 4063072 4063362 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11259647, 8821938; Product type f : factor; 10 kDa chaperonin (Protein Cpn10) (groES protein) complement(4063072..4063362) Methylobacterium extorquens DM4 8195532 YP_003069608.1 CDS METDI4131 NC_012988.1 4063626 4064849 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15661012; Product type pe : putative enzyme; putative acyl-CoA dehydrogenase complement(4063626..4064849) Methylobacterium extorquens DM4 8195534 YP_003069609.1 CDS METDI4132 NC_012988.1 4065169 4067577 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4065169..4067577) Methylobacterium extorquens DM4 8193613 YP_003069610.1 CDS METDI4133 NC_012988.1 4067723 4068763 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8011666, 9384377, 9782504; Product type pt : putative transporter; putative extracellular solute-binding protein precursor, putative sulfonate-binding protein precursor 4067723..4068763 Methylobacterium extorquens DM4 8193614 YP_003069611.1 CDS METDI4134 NC_012988.1 4068765 4069985 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfite oxidase precursor (tat pathway signal) 4068765..4069985 Methylobacterium extorquens DM4 8193615 YP_003069612.1 CDS METDI4135 NC_012988.1 4069975 4070559 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; Cytochrome c, class I precursor 4069975..4070559 Methylobacterium extorquens DM4 8193616 YP_003069613.1 CDS ssuA NC_012988.1 4070556 4071524 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10361295, 10506196; Product type t : transporter; alkanesulfonate transport protein, periplasmic-binding subunit, ABC superfamily (tat pathway signal) 4070556..4071524 Methylobacterium extorquens DM4 8193617 YP_003069614.1 CDS ssuD NC_012988.1 4071521 4072576 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9782504; Product type e : enzyme; Alkanesulfonate monooxygenase 4071521..4072576 Methylobacterium extorquens DM4 8196150 YP_003069615.1 CDS ygfU NC_012988.1 4072573 4073982 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; transporter 4072573..4073982 Methylobacterium extorquens DM4 8196161 YP_003069616.1 CDS nahD NC_012988.1 4073898 4074554 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2-hydroxychromene-2-carboxylate isomerase (HCCA isomerase) complement(4073898..4074554) Methylobacterium extorquens DM4 8196365 YP_003069617.1 CDS ssuB NC_012988.1 4074551 4075432 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ATP-binding component of ABC superfamily; putative alkanesulfonate transporter subunit complement(4074551..4075432) Methylobacterium extorquens DM4 8195770 YP_003069618.1 CDS METDI4141 NC_012988.1 4075429 4076304 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC superfamily transporter membrane protein complement(4075429..4076304) Methylobacterium extorquens DM4 8196155 YP_003069619.1 CDS METDI4142 NC_012988.1 4076301 4077743 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC family transporter, periplasmic protein complement(4076301..4077743) Methylobacterium extorquens DM4 8193618 YP_003069620.1 CDS METDI4143 NC_012988.1 4078080 4078844 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family 4078080..4078844 Methylobacterium extorquens DM4 8193619 YP_003069621.1 CDS METDI4144 NC_012988.1 4078882 4079862 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4078882..4079862) Methylobacterium extorquens DM4 8193620 YP_003069622.1 CDS METDI4145 NC_012988.1 4079859 4080092 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ferredoxin complement(4079859..4080092) Methylobacterium extorquens DM4 8193621 YP_003069623.1 CDS METDI4146 NC_012988.1 4080107 4081870 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase complement(4080107..4081870) Methylobacterium extorquens DM4 8193622 YP_003069624.1 CDS METDI4147 NC_012988.1 4081867 4082190 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4081867..4082190) Methylobacterium extorquens DM4 8193623 YP_003069625.1 CDS METDI4148 NC_012988.1 4082727 4082906 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4082727..4082906) Methylobacterium extorquens DM4 8193624 YP_003069626.1 CDS METDI4149 NC_012988.1 4083312 4085339 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane protein, diguanylate cyclase (GGDEF) domain complement(4083312..4085339) Methylobacterium extorquens DM4 8193625 YP_003069627.1 CDS METDI4150 NC_012988.1 4085408 4085578 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4085408..4085578) Methylobacterium extorquens DM4 8193626 YP_003069628.1 CDS METDI4151 NC_012988.1 4085750 4086775 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4085750..4086775 Methylobacterium extorquens DM4 8193627 YP_003069629.1 CDS METDI4154 NC_012988.1 4087416 4087739 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative elongation factor, GreA/GreB family complement(4087416..4087739) Methylobacterium extorquens DM4 8193630 YP_003069630.1 CDS METDI4156 NC_012988.1 4088724 4089209 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4088724..4089209 Methylobacterium extorquens DM4 8193631 YP_003069631.1 CDS METDI4157 NC_012988.1 4089504 4089734 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4089504..4089734) Methylobacterium extorquens DM4 8193632 YP_003069632.1 CDS METDI4158 NC_012988.1 4090035 4090238 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4090035..4090238) Methylobacterium extorquens DM4 8193633 YP_003069633.1 CDS METDI4159 NC_012988.1 4090277 4090621 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4090277..4090621) Methylobacterium extorquens DM4 8193634 YP_003069634.1 CDS METDI4160 NC_012988.1 4090667 4090969 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4090667..4090969) Methylobacterium extorquens DM4 8193635 YP_003069635.1 CDS METDI4161 NC_012988.1 4091085 4091312 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4091085..4091312 Methylobacterium extorquens DM4 8193636 YP_003069636.1 CDS METDI4162 NC_012988.1 4091338 4093335 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor hybrid histidine kinase with multiple PAS and response regulator receiver domains 4091338..4093335 Methylobacterium extorquens DM4 8193637 YP_003069637.1 CDS METDI4164 NC_012988.1 4093878 4094081 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4093878..4094081) Methylobacterium extorquens DM4 8193639 YP_003069638.1 CDS METDI4165 NC_012988.1 4094417 4095379 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(4094417..4095379) Methylobacterium extorquens DM4 8193640 YP_003069639.1 CDS METDI4168 NC_012988.1 4097001 4097876 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, permease precursor; putative branched-chain amino acid transporter 4097001..4097876 Methylobacterium extorquens DM4 8193643 YP_003069640.1 CDS METDI4169 NC_012988.1 4097873 4099654 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATPase and permease; putative branched-chain amino acid transporter 4097873..4099654 Methylobacterium extorquens DM4 8193644 YP_003069641.1 CDS METDI4170 NC_012988.1 4099654 4100391 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATPase; putative branched-chain amino acid transporter 4099654..4100391 Methylobacterium extorquens DM4 8193645 YP_003069642.1 CDS METDI4171 NC_012988.1 4100473 4101174 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cyclase 4100473..4101174 Methylobacterium extorquens DM4 8193646 YP_003069643.1 CDS METDI4172 NC_012988.1 4101180 4102637 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; amidase-related enzyme 4101180..4102637 Methylobacterium extorquens DM4 8193647 YP_003069644.1 CDS METDI4173 NC_012988.1 4102691 4102903 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4102691..4102903) Methylobacterium extorquens DM4 8193648 YP_003069645.1 CDS amiE NC_012988.1 4103175 4104227 R aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase complement(4103175..4104227) Methylobacterium extorquens DM4 8193649 YP_003069646.1 CDS METDI4175 NC_012988.1 4104303 4105718 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative carbohydrate-selective porin complement(4104303..4105718) Methylobacterium extorquens DM4 8195071 YP_003069647.1 CDS METDI4176 NC_012988.1 4105930 4106247 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative formamidase regulatory protein, FmdB family complement(4105930..4106247) Methylobacterium extorquens DM4 8193650 YP_003069648.1 CDS fmdA NC_012988.1 4106312 4107541 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8841393; Product type e : enzyme; formamidase complement(4106312..4107541) Methylobacterium extorquens DM4 8193651 YP_003069649.1 CDS METDI4178 NC_012988.1 4107705 4108721 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(4107705..4108721) Methylobacterium extorquens DM4 8195432 YP_003069650.1 CDS METDI4179 NC_012988.1 4108733 4109479 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATP-binding component complement(4108733..4109479) Methylobacterium extorquens DM4 8193652 YP_003069651.1 CDS METDI4180 NC_012988.1 4109493 4110281 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative leucine/isoleucine/valine transporter subunit (ATP-binding component of ABC superfamily) (livG) complement(4109493..4110281) Methylobacterium extorquens DM4 8193653 YP_003069652.1 CDS METDI4181 NC_012988.1 4110293 4111450 R Evidence 2b : Function of strongly homologous gene; Product type pt : putative transporter; putative branched-chain amino acid ABC transporter, permease protein complement(4110293..4111450) Methylobacterium extorquens DM4 8193654 YP_003069653.1 CDS METDI4182 NC_012988.1 4111488 4112414 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative branched-chain amino acid ABC transporter, permease protein complement(4111488..4112414) Methylobacterium extorquens DM4 8193655 YP_003069654.1 CDS METDI4183 NC_012988.1 4112524 4113777 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; putative branched-chain amino acid ABC transporter, substrate-binding protein complement(4112524..4113777) Methylobacterium extorquens DM4 8193656 YP_003069655.1 CDS METDI4184 NC_012988.1 4114271 4117450 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor hybrid histidine kinase 4114271..4117450 Methylobacterium extorquens DM4 8193657 YP_003069656.1 CDS METDI4185 NC_012988.1 4117443 4118351 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator; input and output domains: CheY and LuxR family 4117443..4118351 Methylobacterium extorquens DM4 8193658 YP_003069657.1 CDS METDI4186 NC_012988.1 4118870 4119673 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4118870..4119673 Methylobacterium extorquens DM4 8193659 YP_003069659.1 CDS cobF NC_012988.1 4120224 4120982 D [deacetylating]; catalyzes the formation of precorrin 6x from precorrin 5; precorrin 6A synthase 4120224..4120982 Methylobacterium extorquens DM4 8193661 YP_003069660.1 CDS METDI4189 NC_012988.1 4121204 4122544 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4121204..4122544 Methylobacterium extorquens DM4 8195186 YP_003069661.1 CDS METDI4190 NC_012988.1 4122564 4123130 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4122564..4123130) Methylobacterium extorquens DM4 8193662 YP_003069662.1 CDS METDI4191 NC_012988.1 4123491 4124180 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATPase, putative partition protein (ParA) 4123491..4124180 Methylobacterium extorquens DM4 8193663 YP_003069663.1 CDS METDI4192 NC_012988.1 4124164 4124517 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4124164..4124517 Methylobacterium extorquens DM4 8193664 YP_003069664.1 CDS METDI4193 NC_012988.1 4124785 4126209 D Evidence 2b : Function of strongly homologous gene; Product type lp : lipoprotein; rare lipoprotein A family protein 4124785..4126209 Methylobacterium extorquens DM4 8193665 YP_003069665.1 CDS METDI4194 NC_012988.1 4126388 4128286 R Evidence 5 : No homology to any previously reported sequences; PubMedId : 15188393, 16926146; hypothetical protein complement(4126388..4128286) Methylobacterium extorquens DM4 8193666 YP_003069666.1 CDS METDI4195 NC_012988.1 4128494 4128820 R Evidence 2b : Function of strongly homologous gene; PubMedId : 17698959; Product type f : factor; iron-sulfur cluster assembly accessory protein complement(4128494..4128820) Methylobacterium extorquens DM4 8193667 YP_003069667.1 CDS dgt NC_012988.1 4128947 4130200 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11756688; Product type e : enzyme; Deoxyguanosinetriphosphate triphosphohydrolase-like protein 4128947..4130200 Methylobacterium extorquens DM4 8193668 YP_003069668.1 CDS METDI4197 NC_012988.1 4130228 4130761 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4130228..4130761) Methylobacterium extorquens DM4 8195293 YP_003069669.1 CDS METDI4198 NC_012988.1 4130891 4131352 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; thioesterase superfamily protein 4130891..4131352 Methylobacterium extorquens DM4 8193669 YP_003069670.1 CDS argS NC_012988.1 4131447 4133204 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; arginyl-tRNA synthetase 4131447..4133204 Methylobacterium extorquens DM4 8193670 YP_003069671.1 CDS METDI4200 NC_012988.1 4133234 4134640 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4133234..4134640 Methylobacterium extorquens DM4 8195091 YP_003069672.1 CDS METDI4201 NC_012988.1 4134850 4135881 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative beta N-acetyl-glucosaminidase (nagZ-like) 4134850..4135881 Methylobacterium extorquens DM4 8193671 YP_003069673.1 CDS tatA NC_012988.1 4136147 4136434 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4136147..4136434 Methylobacterium extorquens DM4 8193672 YP_003069674.1 CDS tatB NC_012988.1 4136578 4137039 D Evidence 2b : Function of strongly homologous gene; Product type pt : putative transporter; Sec-independent protein translocase protein 4136578..4137039 Methylobacterium extorquens DM4 8196179 YP_003069675.1 CDS tatC NC_012988.1 4137036 4137836 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Sec-independent protein translocase protein 4137036..4137836 Methylobacterium extorquens DM4 8196180 YP_003069676.1 CDS METDI4206 NC_012988.1 4137997 4138695 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4137997..4138695 Methylobacterium extorquens DM4 8196181 YP_003069677.1 CDS METDI4207 NC_012988.1 4138702 4139877 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transmembrane efflux protein; MFS family (ydhP-like) complement(4138702..4139877) Methylobacterium extorquens DM4 8193673 YP_003069678.1 CDS ssuE NC_012988.1 4140287 4140856 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10049377, 10506196; Product type e : enzyme; NAD(P)H-dependent FMN reductase 4140287..4140856 Methylobacterium extorquens DM4 8193674 YP_003069679.1 CDS ssuA NC_012988.1 4140858 4141841 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10361295, 10506196; Product type t : transporter; alkanesulfonate transport protein, periplasmic-binding subunit, ABC superfamily 4140858..4141841 Methylobacterium extorquens DM4 8196163 YP_003069680.1 CDS ssuC NC_012988.1 4141838 4142698 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10361295, 10506196; Product type t : transporter; alkanesulfonate transport protein, membrane component of ABC superfamily 4141838..4142698 Methylobacterium extorquens DM4 8196151 YP_003069681.1 CDS ssuB NC_012988.1 4142738 4143529 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10361295, 10506196; Product type t : transporter; alkanesulfonate transport protein, ATP-binding protein 4142738..4143529 Methylobacterium extorquens DM4 8196160 YP_003069682.1 CDS ssuD NC_012988.1 4143558 4144733 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10506196; Product type e : enzyme; alkanesulfonate monooxygenase 4143558..4144733 Methylobacterium extorquens DM4 8196156 YP_003069683.1 CDS ssuA NC_012988.1 4144752 4145726 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10361295, 10506196; Product type t : transporter; alkanesulfonate transport protein, periplasmic-binding subunit, ABC superfamily 4144752..4145726 Methylobacterium extorquens DM4 8196162 YP_003069684.1 CDS ssuA NC_012988.1 4145829 4146791 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10361295, 10506196; Product type t : transporter; alkanesulfonate transport protein, periplasmic-binding subunit, ABC superfamily 4145829..4146791 Methylobacterium extorquens DM4 8196152 YP_003069685.1 CDS METDI4215 NC_012988.1 4146826 4148208 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydroxyacylglutathion hydrolase 4146826..4148208 Methylobacterium extorquens DM4 8196153 YP_003069686.1 CDS METDI4216 NC_012988.1 4148543 4148752 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4148543..4148752 Methylobacterium extorquens DM4 8193675 YP_003069687.1 CDS METDI4217 NC_012988.1 4148992 4149669 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4148992..4149669 Methylobacterium extorquens DM4 8193676 YP_003069688.1 CDS METDI4218 NC_012988.1 4149785 4150945 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4149785..4150945) Methylobacterium extorquens DM4 8193677 YP_003069689.1 CDS METDI4219 NC_012988.1 4151126 4154476 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4151126..4154476 Methylobacterium extorquens DM4 8193678 YP_003069690.1 CDS METDI4220 NC_012988.1 4154473 4157013 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4154473..4157013 Methylobacterium extorquens DM4 8193679 YP_003069691.1 CDS METDI4221 NC_012988.1 4157010 4157912 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Transglutaminase-like domain 4157010..4157912 Methylobacterium extorquens DM4 8193680 YP_003069692.1 CDS METDI4222 NC_012988.1 4157926 4158582 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, TetR family complement(4157926..4158582) Methylobacterium extorquens DM4 8193681 YP_003069693.1 CDS METDI4223 NC_012988.1 4158664 4159404 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 4158664..4159404 Methylobacterium extorquens DM4 8193682 YP_003069694.1 CDS METDI4224 NC_012988.1 4159444 4160610 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Drug resistance transporter, Bcr/CflA family complement(4159444..4160610) Methylobacterium extorquens DM4 8193683 YP_003069695.1 CDS METDI4225 NC_012988.1 4160942 4161517 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4160942..4161517) Methylobacterium extorquens DM4 8193684 YP_003069696.1 CDS METDI4226 NC_012988.1 4161762 4163588 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative serine-type D-Ala-D-Ala carboxypeptidase 4161762..4163588 Methylobacterium extorquens DM4 8193685 YP_003069697.1 CDS aldA NC_012988.1 4163777 4165300 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15188393, 16926146, 9511738; Product type e : enzyme; aldehyde dehydrogenase, chloroacetaldehyde dehydrogenase 4163777..4165300 Methylobacterium extorquens DM4 8193686 YP_003069698.1 CDS METDI4228 NC_012988.1 4165823 4167466 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative methyl-accepting chemotaxis sensory transducer precursor 4165823..4167466 Methylobacterium extorquens DM4 8195068 YP_003069699.1 CDS METDI4229 NC_012988.1 4167577 4168866 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6350601; Product type pe : putative enzyme; putative ornithine/diaminopimelate PLP-dependent decarboxylase complement(4167577..4168866) Methylobacterium extorquens DM4 8193687 YP_003069700.1 CDS METDI4230 NC_012988.1 4168872 4170389 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AMP-dependent synthetase and ligase complement(4168872..4170389) Methylobacterium extorquens DM4 8193688 YP_003069701.1 CDS METDI4231 NC_012988.1 4170409 4170660 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative Acyl carrier protein (ACP) complement(4170409..4170660) Methylobacterium extorquens DM4 8193689 YP_003069702.1 CDS METDI4232 NC_012988.1 4170882 4171409 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4170882..4171409 Methylobacterium extorquens DM4 8193690 YP_003069703.1 CDS METDI4233 NC_012988.1 4171366 4172886 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative multidrug efflux protein complement(4171366..4172886) Methylobacterium extorquens DM4 8193691 YP_003069704.1 CDS METDI4234 NC_012988.1 4173144 4174031 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4173144..4174031 Methylobacterium extorquens DM4 8193692 YP_003069705.1 CDS ade NC_012988.1 4174115 4175920 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275; Product type e : enzyme; Adenine deaminase (Adenase) (Adenine aminase) complement(4174115..4175920) Methylobacterium extorquens DM4 8193693 YP_003069706.1 CDS rrmJ NC_012988.1 4176005 4176724 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10748051, 10814528, 10983982, 20287497, 8444796, 92021790, 93186701; Product type e : enzyme; Ribosomal RNA large subunit methyltransferase J (rRNA (uridine-2'-O-)-methyltransferase) (23S rRNA m2U2552 methyltransferase) complement(4176005..4176724) Methylobacterium extorquens DM4 8195063 YP_003069707.1 CDS METDI4237 NC_012988.1 4176908 4178035 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; exopolyphosphatase complement(4176908..4178035) Methylobacterium extorquens DM4 8196083 YP_003069708.1 CDS METDI4238 NC_012988.1 4178182 4179336 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16020541; Product type pe : putative enzyme; putative glycosyl transferase precursor, putative membrane protein complement(4178182..4179336) Methylobacterium extorquens DM4 8193694 YP_003069709.1 CDS METDI4239 NC_012988.1 4179333 4180148 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4179333..4180148) Methylobacterium extorquens DM4 8193695 YP_003069710.1 CDS ctrI NC_012988.1 4180160 4181698 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 14660416; Product type e : enzyme; phytoene desaturase (phytoene dehydrogenase) complement(4180160..4181698) Methylobacterium extorquens DM4 8193696 YP_003069711.1 CDS METDI4241 NC_012988.1 4181797 4182657 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glutamine amidotransferase-like complement(4181797..4182657) Methylobacterium extorquens DM4 8195228 YP_003069712.1 CDS METDI4242 NC_012988.1 4182805 4184031 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative membrane component of an ABC transporter complement(4182805..4184031) Methylobacterium extorquens DM4 8193697 YP_003069713.1 CDS METDI4243 NC_012988.1 4184028 4184996 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Copper ABC transporter (nosF-like) complement(4184028..4184996) Methylobacterium extorquens DM4 8193698 YP_003069714.1 CDS METDI4244 NC_012988.1 4185004 4185432 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4185004..4185432) Methylobacterium extorquens DM4 8193699 YP_003069715.1 CDS METDI4245 NC_012988.1 4185432 4187003 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phytoene dehydrogenase complement(4185432..4187003) Methylobacterium extorquens DM4 8193700 YP_003069716.1 CDS METDI4246 NC_012988.1 4187137 4188636 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4187137..4188636) Methylobacterium extorquens DM4 8193701 YP_003069717.1 CDS spoU NC_012988.1 4188751 4189560 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; TRNA/rRNA methyltransferase (SpoU) complement(4188751..4189560) Methylobacterium extorquens DM4 8193702 YP_003069718.1 CDS croR NC_012988.1 4189630 4190103 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11872727; Product type e : enzyme; crotonase complement(4189630..4190103) Methylobacterium extorquens DM4 8196143 YP_003069719.1 CDS METDI4249 NC_012988.1 4190303 4190920 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4190303..4190920 Methylobacterium extorquens DM4 8195215 YP_003069720.1 CDS METDI4250 NC_012988.1 4190957 4191805 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallophosphoesterase 4190957..4191805 Methylobacterium extorquens DM4 8193703 YP_003069721.1 CDS METDI4251 NC_012988.1 4191898 4192119 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4191898..4192119 Methylobacterium extorquens DM4 8193704 YP_003069722.1 CDS METDI4252 NC_012988.1 4192244 4193386 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4192244..4193386 Methylobacterium extorquens DM4 8193705 YP_003069723.1 CDS METDI4253 NC_012988.1 4193437 4194048 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase 4193437..4194048 Methylobacterium extorquens DM4 8193706 YP_003069724.1 CDS METDI4254 NC_012988.1 4194219 4194431 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4194219..4194431 Methylobacterium extorquens DM4 8193707 YP_003069725.1 CDS gatm NC_012988.1 4194623 4195816 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9148748, 9165070, 9218780, 9915841; Product type e : enzyme; Glycine amidinotransferase (L-arginine:glycine amidinotransferase) complement(4194623..4195816) Methylobacterium extorquens DM4 8193708 YP_003069726.1 CDS METDI4256 NC_012988.1 4196064 4197161 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4196064..4197161 Methylobacterium extorquens DM4 8195472 YP_003069727.1 CDS METDI4257 NC_012988.1 4197152 4197775 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4197152..4197775 Methylobacterium extorquens DM4 8193709 YP_003069728.1 CDS METDI4258 NC_012988.1 4197959 4199155 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase, putative membrane-associated protein 4197959..4199155 Methylobacterium extorquens DM4 8193710 YP_003069729.1 CDS METDI4259 NC_012988.1 4199213 4200637 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Radical SAM superfamily protein 4199213..4200637 Methylobacterium extorquens DM4 8193711 YP_003069730.1 CDS METDI4260 NC_012988.1 4200767 4201609 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4200767..4201609 Methylobacterium extorquens DM4 8193712 YP_003069731.1 CDS METDI4261 NC_012988.1 4201852 4202355 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4201852..4202355 Methylobacterium extorquens DM4 8193713 YP_003069732.1 CDS METDI4262 NC_012988.1 4202490 4205138 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane protein with sterol sensing domain; putative exporter, RND family complement(4202490..4205138) Methylobacterium extorquens DM4 8193714 YP_003069733.1 CDS METDI4263 NC_012988.1 4205886 4207049 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Radical SAM superfamily protein 4205886..4207049 Methylobacterium extorquens DM4 8193715 YP_003069734.1 CDS METDI4264 NC_012988.1 4207248 4207955 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleoside phosphorylase complement(4207248..4207955) Methylobacterium extorquens DM4 8193716 YP_003069735.1 CDS METDI4265 NC_012988.1 4207952 4209118 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11373120; Product type pt : putative transporter; putative capsule polysaccharide export outer membrane protein complement(4207952..4209118) Methylobacterium extorquens DM4 8193717 YP_003069736.1 CDS gntK NC_012988.1 4209424 4209966 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11468405, 8655507; Product type e : enzyme; gluconokinase; gluconate transport, GNT I system 4209424..4209966 Methylobacterium extorquens DM4 8193718 YP_003069737.1 CDS METDI4267 NC_012988.1 4209975 4210778 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase, Cof-subfamily 4209975..4210778 Methylobacterium extorquens DM4 8195526 YP_003069738.1 CDS METDI4268 NC_012988.1 4211025 4211918 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4211025..4211918 Methylobacterium extorquens DM4 8193719 YP_003069739.1 CDS rpmF NC_012988.1 4212076 4212264 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 4212076..4212264 Methylobacterium extorquens DM4 8193720 YP_003069740.1 CDS METDI4270 NC_012988.1 4212332 4212652 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4212332..4212652 Methylobacterium extorquens DM4 8196040 YP_003069741.1 CDS phaR NC_012988.1 4212816 4213418 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type pr : putative regulator; putative regulator for granule-associated proteins, PHB biosynthesis and acetyl-CoA flux complement(4212816..4213418) Methylobacterium extorquens DM4 8193721 YP_003069742.1 CDS phaA NC_012988.1 4213744 4214928 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11208803; Product type e : enzyme; beta-ketothiolase 4213744..4214928 Methylobacterium extorquens DM4 8195857 YP_003069743.1 CDS phaB NC_012988.1 4215201 4215929 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11208803; Product type e : enzyme; acetoacetyl-CoA reductase 4215201..4215929 Methylobacterium extorquens DM4 8195854 YP_003069744.1 CDS lpxM NC_012988.1 4216085 4217059 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 4216085..4217059 Methylobacterium extorquens DM4 8195855 YP_003069745.1 CDS METDI4275 NC_012988.1 4217088 4218347 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aminopeptidase complement(4217088..4218347) Methylobacterium extorquens DM4 8195651 YP_003069746.1 CDS METDI4276 NC_012988.1 4218425 4218718 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4218425..4218718) Methylobacterium extorquens DM4 8193722 YP_003069747.1 CDS METDI4277 NC_012988.1 4219096 4220547 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative D-lactate dehydrogenase (cytochrome) complement(4219096..4220547) Methylobacterium extorquens DM4 8193723 YP_003069748.1 CDS METDI4278 NC_012988.1 4220755 4221450 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Fumarylacetoacetate (FAA) hydrolase 4220755..4221450 Methylobacterium extorquens DM4 8193724 YP_003069749.1 CDS METDI4279 NC_012988.1 4221447 4221974 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NUDIX superfamily hydrolase 4221447..4221974 Methylobacterium extorquens DM4 8193725 YP_003069750.1 CDS METDI4280 NC_012988.1 4222420 4223697 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; DegT/DnrJ/EryC1/StrS aminotransferase 4222420..4223697 Methylobacterium extorquens DM4 8196226 YP_003069751.1 CDS METDI4281 NC_012988.1 4223853 4224539 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4223853..4224539) Methylobacterium extorquens DM4 8193727 YP_003069752.1 CDS METDI4282 NC_012988.1 4224723 4225772 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Regulatory protein, LysR family 4224723..4225772 Methylobacterium extorquens DM4 8193728 YP_003069753.1 CDS METDI4283 NC_012988.1 4226166 4226915 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family 4226166..4226915 Methylobacterium extorquens DM4 8193729 YP_003069754.1 CDS METDI4284 NC_012988.1 4227098 4227376 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4227098..4227376) Methylobacterium extorquens DM4 8193730 YP_003069755.1 CDS METDI4285 NC_012988.1 4227469 4227678 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4227469..4227678) Methylobacterium extorquens DM4 8193731 YP_003069756.1 CDS METDI4286 NC_012988.1 4227696 4227959 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4227696..4227959 Methylobacterium extorquens DM4 8193732 YP_003069757.1 CDS METDI4287 NC_012988.1 4228090 4228512 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4228090..4228512 Methylobacterium extorquens DM4 8193733 YP_003069758.1 CDS METDI4288 NC_012988.1 4228613 4229689 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyl-CoA dehydrogenase complement(4228613..4229689) Methylobacterium extorquens DM4 8193734 YP_003069759.1 CDS METDI4289 NC_012988.1 4229695 4230252 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4229695..4230252) Methylobacterium extorquens DM4 8193735 YP_003069760.1 CDS METDI4290 NC_012988.1 4230263 4231120 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, permease complement(4230263..4231120) Methylobacterium extorquens DM4 8193736 YP_003069761.1 CDS METDI4291 NC_012988.1 4231117 4232343 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein complement(4231117..4232343) Methylobacterium extorquens DM4 8193737 YP_003069762.1 CDS METDI4292 NC_012988.1 4232330 4233121 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATPase complement(4232330..4233121) Methylobacterium extorquens DM4 8193738 YP_003069763.1 CDS METDI4293 NC_012988.1 4233793 4235247 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative carbohydrate-selective porin 4233793..4235247 Methylobacterium extorquens DM4 8193739 YP_003069764.1 CDS METDI4294 NC_012988.1 4235303 4236706 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Monooxygenase, NtaA/SnaA/SoxA family 4235303..4236706 Methylobacterium extorquens DM4 8193740 YP_003069765.1 CDS livG NC_012988.1 4236712 4237482 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Branched-chain amino acid ABC transporter, ATP-binding protein 4236712..4237482 Methylobacterium extorquens DM4 8193741 YP_003069766.1 CDS METDI4296 NC_012988.1 4237493 4238374 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Branched-chain amino acid ABC transporter, permease protein 4237493..4238374 Methylobacterium extorquens DM4 8195639 YP_003069767.1 CDS METDI4297 NC_012988.1 4238379 4239422 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative branched-chain amino acid transport system permease protein 4238379..4239422 Methylobacterium extorquens DM4 8193742 YP_003069768.1 CDS METDI4298 NC_012988.1 4239458 4240831 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4239458..4240831 Methylobacterium extorquens DM4 8193743 YP_003069769.1 CDS livF NC_012988.1 4240828 4241589 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14702302, 2195019, 90307651; Product type t : transporter; leucine/isoleucine/valine transporter subunit ; ATP-binding component of ABC superfamily 4240828..4241589 Methylobacterium extorquens DM4 8193744 YP_003069770.1 CDS METDI4300 NC_012988.1 4241621 4242883 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15661012; Product type pe : putative enzyme; acyl-CoA dehydrogenase 4241621..4242883 Methylobacterium extorquens DM4 8195638 YP_003069771.1 CDS METDI4301 NC_012988.1 4243056 4243343 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4243056..4243343 Methylobacterium extorquens DM4 8193745 YP_003069772.1 CDS METDI4302 NC_012988.1 4243422 4243898 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative molecular chaperone, heat shock Hsp20 family 4243422..4243898 Methylobacterium extorquens DM4 8193746 YP_003069773.1 CDS METDI4303 NC_012988.1 4243895 4244770 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family 4243895..4244770 Methylobacterium extorquens DM4 8193747 YP_003069774.1 CDS METDI4304 NC_012988.1 4244859 4245671 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; UspA (universal stress protein) domain protein 4244859..4245671 Methylobacterium extorquens DM4 8193748 YP_003069775.1 CDS METDI4305 NC_012988.1 4245816 4246265 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4245816..4246265 Methylobacterium extorquens DM4 8193749 YP_003069776.1 CDS METDI4306 NC_012988.1 4246296 4246622 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4246296..4246622) Methylobacterium extorquens DM4 8193750 YP_003069777.1 CDS METDI4307 NC_012988.1 4246655 4246876 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4246655..4246876) Methylobacterium extorquens DM4 8193751 YP_003069778.1 CDS METDI4308 NC_012988.1 4246854 4247198 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4246854..4247198 Methylobacterium extorquens DM4 8193752 YP_003069779.1 CDS METDI4309 NC_012988.1 4247141 4248001 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4247141..4248001 Methylobacterium extorquens DM4 8193753 YP_003069780.1 CDS METDI4310 NC_012988.1 4247998 4248111 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4247998..4248111 Methylobacterium extorquens DM4 8193754 YP_003069781.1 CDS METDI4311 NC_012988.1 4248119 4248808 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family complement(4248119..4248808) Methylobacterium extorquens DM4 8193755 YP_003069782.1 CDS fixJ NC_012988.1 4249347 4249955 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; two component transcriptional regulator, LuxR family; putative nitrogen fixation transcriptional regulator FixJ complement(4249347..4249955) Methylobacterium extorquens DM4 8193756 YP_003069783.1 CDS fixL NC_012988.1 4249959 4251506 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; two component low oxygen sensor histidine kinase with PAS domains, FixL complement(4249959..4251506) Methylobacterium extorquens DM4 8195378 YP_003069784.1 CDS METDI4314 NC_012988.1 4251853 4252713 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4251853..4252713 Methylobacterium extorquens DM4 8195383 YP_003069785.1 CDS METDI4315 NC_012988.1 4252931 4253986 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal dependent phosphohydrolase with a response regulator receiver domain; HD-GYP domain protein 4252931..4253986 Methylobacterium extorquens DM4 8193757 YP_003069786.1 CDS METDI4316 NC_012988.1 4254102 4256846 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1314807; Product type pe : putative enzyme; putative sensor protein gacS (Synonyms : lemA) complement(4254102..4256846) Methylobacterium extorquens DM4 8193758 YP_003069787.1 CDS METDI4317 NC_012988.1 4257014 4258435 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4257014..4258435) Methylobacterium extorquens DM4 8193759 YP_003069788.1 CDS METDI4318 NC_012988.1 4258634 4259242 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4258634..4259242) Methylobacterium extorquens DM4 8193760 YP_003069789.1 CDS METDI4319 NC_012988.1 4259239 4259754 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4259239..4259754) Methylobacterium extorquens DM4 8193761 YP_003069790.1 CDS METDI4322 NC_012988.1 4261602 4261949 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4261602..4261949 Methylobacterium extorquens DM4 8193764 YP_003069791.1 CDS METDI4323 NC_012988.1 4262038 4262274 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4262038..4262274 Methylobacterium extorquens DM4 8193765 YP_003069792.1 CDS METDI4324 NC_012988.1 4262631 4263314 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nuclease 4262631..4263314 Methylobacterium extorquens DM4 8193766 YP_003069793.1 CDS METDI4325 NC_012988.1 4263369 4263635 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4263369..4263635 Methylobacterium extorquens DM4 8193767 YP_003069794.1 CDS METDI4326 NC_012988.1 4263714 4263908 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4263714..4263908 Methylobacterium extorquens DM4 8193768 YP_003069795.1 CDS METDI4327 NC_012988.1 4264257 4265297 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4264257..4265297 Methylobacterium extorquens DM4 8193769 YP_003069796.1 CDS umuC NC_012988.1 4265341 4266672 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2989816, 2989817; Product type e : enzyme; component of DNA polymerase V, subunit C complement(4265341..4266672) Methylobacterium extorquens DM4 8193770 YP_003069797.1 CDS umuD NC_012988.1 4266669 4267061 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2989816; Product type e : enzyme; component of DNA polymerase V, subunit D complement(4266669..4267061) Methylobacterium extorquens DM4 8196300 YP_003069798.1 CDS METDI4330 NC_012988.1 4267225 4267515 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4267225..4267515 Methylobacterium extorquens DM4 8196302 YP_003069799.1 CDS METDI4331 NC_012988.1 4267782 4267994 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4267782..4267994 Methylobacterium extorquens DM4 8193771 YP_003069800.1 CDS METDI4332 NC_012988.1 4268097 4268387 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4268097..4268387) Methylobacterium extorquens DM4 8193772 YP_003069801.1 CDS METDI4333 NC_012988.1 4268387 4268575 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4268387..4268575 Methylobacterium extorquens DM4 8193773 YP_003069802.1 CDS METDI4334 NC_012988.1 4268800 4269084 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, XRE family 4268800..4269084 Methylobacterium extorquens DM4 8193774 YP_003069803.1 CDS METDI4336 NC_012988.1 4269339 4270580 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4269339..4270580) Methylobacterium extorquens DM4 8193775 YP_003069804.1 CDS METDI4339 NC_012988.1 4272968 4273222 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4272968..4273222) Methylobacterium extorquens DM4 8193778 YP_003069805.1 CDS METDI4340 NC_012988.1 4273950 4274873 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(4273950..4274873) Methylobacterium extorquens DM4 8193779 YP_003069806.1 CDS METDI4345 NC_012988.1 4277440 4277628 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4277440..4277628 Methylobacterium extorquens DM4 8193784 YP_003069807.1 CDS METDI4346 NC_012988.1 4277582 4278133 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4277582..4278133) Methylobacterium extorquens DM4 8193785 YP_003069808.1 CDS METDI4347 NC_012988.1 4278287 4278463 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4278287..4278463) Methylobacterium extorquens DM4 8193786 YP_003069809.1 CDS METDI4348 NC_012988.1 4278430 4278801 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4278430..4278801) Methylobacterium extorquens DM4 8193787 YP_003069810.1 CDS METDI4349 NC_012988.1 4278820 4279302 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4278820..4279302) Methylobacterium extorquens DM4 8193788 YP_003069811.1 CDS METDI4350 NC_012988.1 4279299 4279658 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4279299..4279658) Methylobacterium extorquens DM4 8193789 YP_003069812.1 CDS METDI4351 NC_012988.1 4279702 4280265 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4279702..4280265) Methylobacterium extorquens DM4 8193790 YP_003069813.1 CDS METDI4352 NC_012988.1 4280452 4281150 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4280452..4281150) Methylobacterium extorquens DM4 8193791 YP_003069814.1 CDS METDI4353 NC_012988.1 4281215 4281643 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4281215..4281643) Methylobacterium extorquens DM4 8193792 YP_003069815.1 CDS METDI4354 NC_012988.1 4281682 4282590 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4281682..4282590) Methylobacterium extorquens DM4 8193793 YP_003069816.1 CDS METDI4355 NC_012988.1 4282550 4282960 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10400574; Product type e : enzyme; Excisionase 4282550..4282960 Methylobacterium extorquens DM4 8193794 YP_003069817.1 CDS METDI4356 NC_012988.1 4282759 4283718 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phage integrase 4282759..4283718 Methylobacterium extorquens DM4 8193795 YP_003069818.1 CDS METDI4357 NC_012988.1 4283693 4285018 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phage integrase complement(4283693..4285018) Methylobacterium extorquens DM4 8193796 YP_003069819.1 CDS METDI4358 NC_012988.1 4284829 4285281 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10400574; Product type pe : putative enzyme; hypothetical protein complement(4284829..4285281) Methylobacterium extorquens DM4 8193797 YP_003069820.1 CDS METDI4359 NC_012988.1 4285372 4286250 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4285372..4286250) Methylobacterium extorquens DM4 8193798 YP_003069821.1 CDS METDI4360 NC_012988.1 4286250 4287056 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4286250..4287056) Methylobacterium extorquens DM4 8193799 YP_003069822.1 CDS METDI4361 NC_012988.1 4287067 4287279 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4287067..4287279) Methylobacterium extorquens DM4 8193800 YP_003069823.1 CDS METDI4362 NC_012988.1 4287231 4288061 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4287231..4288061) Methylobacterium extorquens DM4 8193801 YP_003069824.1 CDS METDI4363 NC_012988.1 4288061 4288273 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4288061..4288273) Methylobacterium extorquens DM4 8193802 YP_003069825.1 CDS METDI4364 NC_012988.1 4288270 4288749 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4288270..4288749) Methylobacterium extorquens DM4 8193803 YP_003069826.1 CDS METDI4365 NC_012988.1 4289035 4289754 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4289035..4289754 Methylobacterium extorquens DM4 8193804 YP_003069827.1 CDS METDI4366 NC_012988.1 4289751 4290680 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; adenine-specific DNA methyltransferase 4289751..4290680 Methylobacterium extorquens DM4 8193805 YP_003069828.1 CDS METDI4367 NC_012988.1 4291118 4292527 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4291118..4292527) Methylobacterium extorquens DM4 8193806 YP_003069829.1 CDS METDI4368 NC_012988.1 4292815 4295544 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4292815..4295544 Methylobacterium extorquens DM4 8193807 YP_003069830.1 CDS METDI4369 NC_012988.1 4295541 4296212 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4295541..4296212 Methylobacterium extorquens DM4 8193808 YP_003069831.1 CDS METDI4370 NC_012988.1 4296851 4297093 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4296851..4297093) Methylobacterium extorquens DM4 8193809 YP_003069832.1 CDS METDI4371 NC_012988.1 4297253 4298182 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi4, IS481 family 4297253..4298182 Methylobacterium extorquens DM4 8193810 YP_003069833.1 CDS METDI4372 NC_012988.1 4298187 4298393 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4298187..4298393) Methylobacterium extorquens DM4 8193811 YP_003069834.1 CDS METDI4373 NC_012988.1 4298850 4299455 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4298850..4299455) Methylobacterium extorquens DM4 8193812 YP_003069835.1 CDS METDI4374 NC_012988.1 4299440 4299727 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4299440..4299727 Methylobacterium extorquens DM4 8193813 YP_003069836.1 CDS METDI4375 NC_012988.1 4300210 4300521 D Evidence 6 : Doubtful CDS; Product type e : enzyme; hypothetical protein 4300210..4300521 Methylobacterium extorquens DM4 8193814 YP_003069837.1 CDS METDI4376 NC_012988.1 4300607 4300897 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4300607..4300897 Methylobacterium extorquens DM4 8193815 YP_003069838.1 CDS METDI4377 NC_012988.1 4300703 4300801 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4300703..4300801) Methylobacterium extorquens DM4 8193816 YP_003069839.1 CDS METDI4378 NC_012988.1 4301094 4301471 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4301094..4301471) Methylobacterium extorquens DM4 8193817 YP_003069840.1 CDS METDI4379 NC_012988.1 4301671 4301949 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4301671..4301949 Methylobacterium extorquens DM4 8193818 YP_003069841.1 CDS METDI4380 NC_012988.1 4302097 4302396 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4302097..4302396) Methylobacterium extorquens DM4 8193819 YP_003069842.1 CDS METDI4381 NC_012988.1 4302801 4303109 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4302801..4303109) Methylobacterium extorquens DM4 8193820 YP_003069843.1 CDS METDI4382 NC_012988.1 4304681 4305517 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex11, IS3 family (ORF 2) complement(4304681..4305517) Methylobacterium extorquens DM4 8193821 YP_003069844.1 CDS METDI4383 NC_012988.1 4305514 4305780 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex11, IS3 family (ORF 1) complement(4305514..4305780) Methylobacterium extorquens DM4 8193822 YP_003069845.1 CDS METDI4384 NC_012988.1 4305761 4305991 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4305761..4305991 Methylobacterium extorquens DM4 8193823 YP_003069846.1 CDS METDI4385 NC_012988.1 4306359 4306526 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4306359..4306526) Methylobacterium extorquens DM4 8193824 YP_003069847.1 CDS METDI4387 NC_012988.1 4307089 4307232 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4307089..4307232) Methylobacterium extorquens DM4 8193825 YP_003069848.1 CDS METDI4388 NC_012988.1 4307531 4308130 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4307531..4308130 Methylobacterium extorquens DM4 8193826 YP_003069849.1 CDS METDI4389 NC_012988.1 4308232 4308480 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4308232..4308480 Methylobacterium extorquens DM4 8193827 YP_003069850.1 CDS METDI4390 NC_012988.1 4308682 4308948 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4308682..4308948) Methylobacterium extorquens DM4 8193828 YP_003069851.1 CDS METDI4391 NC_012988.1 4309111 4309356 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4309111..4309356) Methylobacterium extorquens DM4 8193829 YP_003069852.1 CDS METDI4392 NC_012988.1 4309611 4309691 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4309611..4309691) Methylobacterium extorquens DM4 8193830 YP_003069853.1 CDS METDI4393 NC_012988.1 4309981 4310325 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4309981..4310325) Methylobacterium extorquens DM4 8193831 YP_003069854.1 CDS METDI4394 NC_012988.1 4310445 4311263 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4310445..4311263 Methylobacterium extorquens DM4 8193832 YP_003069855.1 CDS METDI4395 NC_012988.1 4311280 4312209 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex17, IS110 family complement(4311280..4312209) Methylobacterium extorquens DM4 8193833 YP_003069856.1 CDS METDI4396 NC_012988.1 4313006 4313908 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Zinc-containing alcohol dehydrogenase superfamily complement(4313006..4313908) Methylobacterium extorquens DM4 8193834 YP_003069857.1 CDS METDI4397 NC_012988.1 4314034 4314873 R Evidence 2b : Function of strongly homologous gene; Product type c : carrier; NADP oxidoreductase, coenzyme F420-dependent complement(4314034..4314873) Methylobacterium extorquens DM4 8193835 YP_003069858.1 CDS METDI4398 NC_012988.1 4314874 4315272 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4314874..4315272 Methylobacterium extorquens DM4 8193836 YP_003069859.1 CDS METDI4399 NC_012988.1 4316014 4316916 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative N-carbamyl-D-amino acid amidohydrolase 4316014..4316916 Methylobacterium extorquens DM4 8193837 YP_003069860.1 CDS METDI4400 NC_012988.1 4316974 4318131 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative extracellular ligand-binding receptor precursor 4316974..4318131 Methylobacterium extorquens DM4 8193838 YP_003069861.1 CDS METDI4401 NC_012988.1 4318162 4319046 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Branched-chain amino acid ABC transporter, permease protein 4318162..4319046 Methylobacterium extorquens DM4 8193839 YP_003069862.1 CDS METDI4402 NC_012988.1 4319039 4320892 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative branched-chain amino acid ABC transporter, permease/ATP-binding protein 4319039..4320892 Methylobacterium extorquens DM4 8193840 YP_003069863.1 CDS METDI4403 NC_012988.1 4320889 4321602 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative leucine/isoleucine/valine transporter subunit (ATP-binding component of ABC superfamily) (livF) 4320889..4321602 Methylobacterium extorquens DM4 8193841 YP_003069864.1 CDS ureAB NC_012988.1 4321599 4322306 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10567266; Product type e : enzyme; urease gamma (N-terminal) and beta (C-terminal) subunits (urea amidohydrolase gamma/beta subunits) 4321599..4322306 Methylobacterium extorquens DM4 8193842 YP_003069865.1 CDS ureC NC_012988.1 4322308 4324023 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 4322308..4324023 Methylobacterium extorquens DM4 8196311 YP_003069866.1 CDS ureG NC_012988.1 4324020 4324643 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15358858, 9125594; Product type e : enzyme; urease accessory protein UreG 4324020..4324643 Methylobacterium extorquens DM4 8196316 YP_003069867.1 CDS METDI4407 NC_012988.1 4324643 4325485 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7813887; Product type pf : putative factor; putative urease accessory protein UreD 4324643..4325485 Methylobacterium extorquens DM4 8196328 YP_003069868.1 CDS ureE NC_012988.1 4325564 4325980 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; urease accessory protein UreE 4325564..4325980 Methylobacterium extorquens DM4 8193843 YP_003069869.1 CDS ureF NC_012988.1 4325970 4326677 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; urease accessory protein UreF 4325970..4326677 Methylobacterium extorquens DM4 8196321 YP_003069870.1 CDS METDI4410 NC_012988.1 4326683 4327192 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10508151, 2495988; Product type pr : putative regulator; putative aliphatic amidase regulator, AmiR complement(4326683..4327192) Methylobacterium extorquens DM4 8196324 YP_003069871.1 CDS METDI4411 NC_012988.1 4327289 4328368 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10508151, 10708652, 1762155, 1907262, 7813419; Product type pr : putative regulator; putative aliphatic amidase expression-regulating protein, AmiC complement(4327289..4328368) Methylobacterium extorquens DM4 8193844 YP_003069872.1 CDS METDI4412 NC_012988.1 4328512 4330068 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein 4328512..4330068 Methylobacterium extorquens DM4 8193845 YP_003069873.1 CDS METDI4413 NC_012988.1 4330065 4330340 D Evidence 6 : Doubtful CDS; hypothetical protein 4330065..4330340 Methylobacterium extorquens DM4 8193846 YP_003069874.1 CDS METDI4414 NC_012988.1 4330840 4332339 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi7, IS21 family (ORF 1) 4330840..4332339 Methylobacterium extorquens DM4 8193847 YP_003069875.1 CDS METDI4415 NC_012988.1 4332336 4333178 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMdi7, IS21 family (ORF 2) 4332336..4333178 Methylobacterium extorquens DM4 8193848 YP_003069876.1 CDS METDI4416 NC_012988.1 4333231 4333512 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4333231..4333512) Methylobacterium extorquens DM4 8193849 YP_003069877.1 CDS METDI4417 NC_012988.1 4335445 4335708 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4335445..4335708) Methylobacterium extorquens DM4 8193850 YP_003069878.1 CDS METDI4419 NC_012988.1 4335839 4336102 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4335839..4336102) Methylobacterium extorquens DM4 8193851 YP_003069879.1 CDS METDI4418 NC_012988.1 4336121 4336261 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4336121..4336261 Methylobacterium extorquens DM4 8193853 YP_003069880.1 CDS METDI4420 NC_012988.1 4336379 4336588 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4336379..4336588 Methylobacterium extorquens DM4 8193852 YP_003069881.1 CDS METDI4421 NC_012988.1 4336653 4338422 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4336653..4338422) Methylobacterium extorquens DM4 8193854 YP_003069882.1 CDS METDI4422 NC_012988.1 4338500 4338937 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4338500..4338937) Methylobacterium extorquens DM4 8193855 YP_003069883.1 CDS METDI4423 NC_012988.1 4339014 4339370 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4339014..4339370) Methylobacterium extorquens DM4 8193856 YP_003069884.1 CDS METDI4424 NC_012988.1 4339620 4340816 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA-directed DNA polymerase complement(4339620..4340816) Methylobacterium extorquens DM4 8193857 YP_003069885.1 CDS METDI4425 NC_012988.1 4340873 4341031 D Evidence 6 : Doubtful CDS; hypothetical protein 4340873..4341031 Methylobacterium extorquens DM4 8193858 YP_003069886.1 CDS METDI4426 NC_012988.1 4341062 4341859 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4341062..4341859 Methylobacterium extorquens DM4 8193859 YP_003069887.1 CDS METDI4427 NC_012988.1 4341861 4342121 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4341861..4342121 Methylobacterium extorquens DM4 8193860 YP_003069888.1 CDS METDI4428 NC_012988.1 4342118 4342360 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4342118..4342360 Methylobacterium extorquens DM4 8193861 YP_003069889.1 CDS METDI4429 NC_012988.1 4342357 4342668 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4342357..4342668 Methylobacterium extorquens DM4 8193862 YP_003069890.1 CDS METDI4430 NC_012988.1 4342904 4343815 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative antirepressor protein 4342904..4343815 Methylobacterium extorquens DM4 8193863 YP_003069891.1 CDS METDI4431 NC_012988.1 4343867 4344379 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4343867..4344379) Methylobacterium extorquens DM4 8193864 YP_003069892.1 CDS METDI4432 NC_012988.1 4344573 4344767 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4344573..4344767 Methylobacterium extorquens DM4 8193865 YP_003069893.1 CDS METDI4433 NC_012988.1 4344828 4345115 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4344828..4345115 Methylobacterium extorquens DM4 8193866 YP_003069894.1 CDS METDI4434 NC_012988.1 4345144 4345611 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4345144..4345611 Methylobacterium extorquens DM4 8193867 YP_003069895.1 CDS METDI4435 NC_012988.1 4345604 4346041 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4345604..4346041 Methylobacterium extorquens DM4 8193868 YP_003069896.1 CDS METDI4437 NC_012988.1 4346474 4347688 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4346474..4347688) Methylobacterium extorquens DM4 8193870 YP_003069897.1 CDS METDI4438 NC_012988.1 4347915 4348115 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4347915..4348115) Methylobacterium extorquens DM4 8193871 YP_003069898.1 CDS METDI4439 NC_012988.1 4348112 4348459 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative repressor with a ribbon-helix-helix domain complement(4348112..4348459) Methylobacterium extorquens DM4 8193872 YP_003069899.1 CDS METDI4440 NC_012988.1 4348633 4349367 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4348633..4349367) Methylobacterium extorquens DM4 8193873 YP_003069900.1 CDS METDI4441 NC_012988.1 4349488 4349859 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4349488..4349859) Methylobacterium extorquens DM4 8193874 YP_003069901.1 CDS METDI4442 NC_012988.1 4350093 4351157 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7750735; Product type pe : putative enzyme; putative transmembrane adenylate/guanylate cyclase complement(4350093..4351157) Methylobacterium extorquens DM4 8193875 YP_003069902.1 CDS cyp NC_012988.1 4351210 4351692 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9851984; Product type f : factor; cytochrome P460 complement(4351210..4351692) Methylobacterium extorquens DM4 8193876 YP_003069903.1 CDS METDI4445 NC_012988.1 4351715 4352839 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative alpha/beta hydrolase, putative epoxide hydrolase, tat pathway signal complement(4351715..4352839) Methylobacterium extorquens DM4 8195247 YP_003069904.1 CDS METDI4446 NC_012988.1 4353093 4354718 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-binding protein with two ATPase domains, ABC transporter related 4353093..4354718 Methylobacterium extorquens DM4 8193877 YP_003069905.1 CDS METDI4447 NC_012988.1 4354748 4356049 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase precursor complement(4354748..4356049) Methylobacterium extorquens DM4 8193878 YP_003069906.1 CDS ompR NC_012988.1 4356046 4356858 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10464234, 2845093, 2997120, 3010044, 6292199, 91175693, 92165726, 93287101; Product type r : regulator; DNA-binding response regulator in two-component regulatory system with EnvZ complement(4356046..4356858) Methylobacterium extorquens DM4 8193879 YP_003069907.1 CDS METDI4449 NC_012988.1 4357148 4357978 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8157602, 9642069; Product type e : enzyme; Non-heme haloperoxidase 4357148..4357978 Methylobacterium extorquens DM4 8195808 YP_003069908.1 CDS METDI4450 NC_012988.1 4358047 4358952 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, lysR family protein complement(4358047..4358952) Methylobacterium extorquens DM4 8193880 YP_003069909.1 CDS METDI4451 NC_012988.1 4359026 4359799 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR 4359026..4359799 Methylobacterium extorquens DM4 8193881 YP_003069910.1 CDS METDI4452 NC_012988.1 4359993 4360955 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor complement(4359993..4360955) Methylobacterium extorquens DM4 8193882 YP_003069911.1 CDS METDI4453 NC_012988.1 4360942 4361367 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4360942..4361367) Methylobacterium extorquens DM4 8193883 YP_003069912.1 CDS METDI4454 NC_012988.1 4361367 4362152 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4361367..4362152) Methylobacterium extorquens DM4 8193884 YP_003069913.1 CDS METDI4455 NC_012988.1 4362087 4363811 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Adenylate cyclase 4362087..4363811 Methylobacterium extorquens DM4 8193885 YP_003069914.1 CDS METDI4456 NC_012988.1 4364191 4365138 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Beta-lactamase-like 4364191..4365138 Methylobacterium extorquens DM4 8193886 YP_003069915.1 CDS METDI4457 NC_012988.1 4365436 4366206 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NAD-dependent epimerase/dehydratase:dTDP-4-dehydrorhamnose reductase:NmrA-like 4365436..4366206 Methylobacterium extorquens DM4 8193887 YP_003069916.1 CDS METDI4458 NC_012988.1 4366219 4366659 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4366219..4366659 Methylobacterium extorquens DM4 8193888 YP_003069917.1 CDS METDI4462 NC_012988.1 4367550 4367945 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4367550..4367945) Methylobacterium extorquens DM4 8193892 YP_003069918.1 CDS METDI4463 NC_012988.1 4368488 4368985 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator (MarR family) 4368488..4368985 Methylobacterium extorquens DM4 8193893 YP_003069919.1 CDS METDI4464 NC_012988.1 4368982 4371012 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative efflux transporter permease, aromatic acid exporter family 4368982..4371012 Methylobacterium extorquens DM4 8193894 YP_003069920.1 CDS METDI4465 NC_012988.1 4371009 4371218 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4371009..4371218 Methylobacterium extorquens DM4 8193895 YP_003069921.1 CDS METDI4466 NC_012988.1 4371264 4372211 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative efflux pump component, secretion protein HlyD family 4371264..4372211 Methylobacterium extorquens DM4 8193896 YP_003069922.1 CDS METDI4467 NC_012988.1 4372272 4373159 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glyoxalase/bleomycin resistance protein/dihydroxybiphenyl dioxygenase 4372272..4373159 Methylobacterium extorquens DM4 8193897 YP_003069923.1 CDS METDI4468 NC_012988.1 4373184 4374446 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; peptidase, putative amidohydrolase complement(4373184..4374446) Methylobacterium extorquens DM4 8193898 YP_003069924.1 CDS METDI4469 NC_012988.1 4374647 4375276 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein complement(4374647..4375276) Methylobacterium extorquens DM4 8193899 YP_003069925.1 CDS METDI4470 NC_012988.1 4375348 4376079 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4375348..4376079) Methylobacterium extorquens DM4 8193900 YP_003069926.1 CDS METDI4471 NC_012988.1 4376832 4377338 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4376832..4377338 Methylobacterium extorquens DM4 8195479 YP_003069927.1 CDS METDI4472 NC_012988.1 4377495 4377944 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7565093; Product type pr : putative regulator; putative regulator 4377495..4377944 Methylobacterium extorquens DM4 8193902 YP_003069928.1 CDS METDI4473 NC_012988.1 4378192 4379121 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp : cell process; putative universal stress protein (Usp) 4378192..4379121 Methylobacterium extorquens DM4 8193903 YP_003069929.1 CDS METDI4474 NC_012988.1 4379196 4379390 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4379196..4379390 Methylobacterium extorquens DM4 8193904 YP_003069930.1 CDS METDI4475 NC_012988.1 4379652 4382420 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL), with PAS sensor, signal transduction histidine kinase and methyl-accepting chemotaxis domains; putative membrane-associated protein precursor complement(4379652..4382420) Methylobacterium extorquens DM4 8195478 YP_003069931.1 CDS METDI4476 NC_012988.1 4382575 4382763 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4382575..4382763 Methylobacterium extorquens DM4 8193906 YP_003069932.1 CDS METDI4477 NC_012988.1 4382847 4383056 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4382847..4383056) Methylobacterium extorquens DM4 8193907 YP_003069933.1 CDS METDI4478 NC_012988.1 4383179 4383406 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcription elongation factor GreA-related complement(4383179..4383406) Methylobacterium extorquens DM4 8193908 YP_003069934.1 CDS METDI4479 NC_012988.1 4384670 4384981 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4384670..4384981) Methylobacterium extorquens DM4 8193909 YP_003069935.1 CDS hss NC_012988.1 4385032 4386468 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8841401; Product type e : enzyme; homospermidine synthase 4385032..4386468 Methylobacterium extorquens DM4 8193910 YP_003069936.1 CDS METDI4481 NC_012988.1 4386557 4387735 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, putative amine oxidase 4386557..4387735 Methylobacterium extorquens DM4 8195581 YP_003069937.1 CDS serC2 NC_012988.1 4387735 4388976 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 4387735..4388976 Methylobacterium extorquens DM4 8193911 YP_003069938.1 CDS gdhA NC_012988.1 4389103 4390365 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10366510, 12013436, 9135121, 9654452; Product type e : enzyme; glutamate dehydrogenase (NAD(P)+) oxidoreductase protein 4389103..4390365 Methylobacterium extorquens DM4 8196112 YP_003069939.1 CDS METDI4484 NC_012988.1 4390568 4391338 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15601702; Product type pe : putative enzyme; putative pseudouridine synthase, putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4390568..4391338 Methylobacterium extorquens DM4 8195481 YP_003069940.1 CDS ispF NC_012988.1 4391137 4391871 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10419959, 10694574, 12211023; Product type e : enzyme; 2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase (MECPS, MECDP-synthase) 4391137..4391871 Methylobacterium extorquens DM4 8193912 YP_003069941.1 CDS METDI4486 NC_012988.1 4392347 4392718 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4392347..4392718) Methylobacterium extorquens DM4 8195610 YP_003069942.1 CDS METDI4487 NC_012988.1 4392854 4393993 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4392854..4393993 Methylobacterium extorquens DM4 8193913 YP_003069943.1 CDS metB NC_012988.1 4394623 4395567 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15581575, 9843488; Product type e : enzyme; cystathionine gamma-synthase, PLP-dependent complement(4394623..4395567) Methylobacterium extorquens DM4 8193914 YP_003069944.1 CDS METDI4489 NC_012988.1 4396017 4396493 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16885456; Product type r : regulator; transcriptional regulator, rrf2 family complement(4396017..4396493) Methylobacterium extorquens DM4 8195680 YP_003069945.1 CDS hmp NC_012988.1 4396589 4397830 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 4396589..4397830 Methylobacterium extorquens DM4 8193915 YP_003069946.1 CDS METDI4491 NC_012988.1 4397885 4398328 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative PAS/PAC sensor protein 4397885..4398328 Methylobacterium extorquens DM4 8195568 YP_003069947.1 CDS METDI4492 NC_012988.1 4398346 4399140 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 5-formyltetrahydrofolate cyclo-ligase 4398346..4399140 Methylobacterium extorquens DM4 8193916 YP_003069948.1 CDS METDI4493 NC_012988.1 4399353 4400045 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, GntR family 4399353..4400045 Methylobacterium extorquens DM4 8193917 YP_003069949.1 CDS METDI4496 NC_012988.1 4400950 4402599 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex10, ISL3 family 4400950..4402599 Methylobacterium extorquens DM4 8193920 YP_003069950.1 CDS METDI4497 NC_012988.1 4402643 4402849 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4402643..4402849 Methylobacterium extorquens DM4 8193921 YP_003069951.1 CDS METDI4498 NC_012988.1 4402932 4403456 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10656595, 11481430, 2013576, 7756693; Product type r : regulator; transcriptional regulator, Ros/MucR family complement(4402932..4403456) Methylobacterium extorquens DM4 8193922 YP_003069952.1 CDS METDI4499 NC_012988.1 4403576 4403851 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4403576..4403851) Methylobacterium extorquens DM4 8193923 YP_003069953.1 CDS METDI4500 NC_012988.1 4404036 4404230 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4404036..4404230 Methylobacterium extorquens DM4 8193924 YP_003069954.1 CDS METDI4501 NC_012988.1 4404593 4405054 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15716451; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF motif) 4404593..4405054 Methylobacterium extorquens DM4 8193925 YP_003069955.1 CDS METDI4502 NC_012988.1 4405190 4406002 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7619830; Product type pc : putative carrier; putative cytochrome c complement(4405190..4406002) Methylobacterium extorquens DM4 8193926 YP_003069956.1 CDS METDI4503 NC_012988.1 4405999 4407621 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10775261; Product type pe : putative enzyme; putative Cytochrome c oxidase, subunit I complement(4405999..4407621) Methylobacterium extorquens DM4 8193927 YP_003069957.1 CDS METDI4504 NC_012988.1 4407611 4408174 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10775261; Product type pe : putative enzyme; putative Cytochrome c oxidase, subunit II complement(4407611..4408174) Methylobacterium extorquens DM4 8193928 YP_003069958.1 CDS METDI4505 NC_012988.1 4408187 4408363 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4408187..4408363) Methylobacterium extorquens DM4 8193929 YP_003069959.1 CDS METDI4506 NC_012988.1 4408368 4409639 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9352901; Product type pc : putative carrier; putative cytochrome c, putative exported protein complement(4408368..4409639) Methylobacterium extorquens DM4 8193930 YP_003069960.1 CDS METDI4507 NC_012988.1 4409636 4410235 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome c complement(4409636..4410235) Methylobacterium extorquens DM4 8193931 YP_003069961.1 CDS METDI4508 NC_012988.1 4410803 4411414 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8759861; Product type pr : putative regulator; putative nitric oxide responsive transcriptional regulator NnrR, Crp/Fnr family 4410803..4411414 Methylobacterium extorquens DM4 8193932 YP_003069962.1 CDS METDI4509 NC_012988.1 4411616 4411852 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4411616..4411852 Methylobacterium extorquens DM4 8193933 YP_003069963.1 CDS METDI4510 NC_012988.1 4411838 4412053 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4411838..4412053) Methylobacterium extorquens DM4 8193934 YP_003069964.1 CDS METDI4511 NC_012988.1 4412135 4412407 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4412135..4412407) Methylobacterium extorquens DM4 8193935 YP_003069965.1 CDS METDI4512 NC_012988.1 4412388 4412654 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex11, IS3 family (ORF 1) 4412388..4412654 Methylobacterium extorquens DM4 8193936 YP_003069966.1 CDS METDI4513 NC_012988.1 4412651 4413487 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex11, IS3 family (ORF 2) 4412651..4413487 Methylobacterium extorquens DM4 8193937 YP_003069967.1 CDS METDI4514 NC_012988.1 4413995 4415275 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, SulP family complement(4413995..4415275) Methylobacterium extorquens DM4 8193938 YP_003069968.1 CDS METDI4515 NC_012988.1 4416003 4417028 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Histone deacetylase family protein 4416003..4417028 Methylobacterium extorquens DM4 8193939 YP_003069969.1 CDS METDI4517 NC_012988.1 4417331 4417780 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4417331..4417780) Methylobacterium extorquens DM4 8193940 YP_003069970.1 CDS METDI4519 NC_012988.1 4418162 4418641 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative molecular chaperone, heat shock Hsp20 family 4418162..4418641 Methylobacterium extorquens DM4 8193941 YP_003069971.1 CDS METDI4520 NC_012988.1 4418641 4419498 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family 4418641..4419498 Methylobacterium extorquens DM4 8193942 YP_003069972.1 CDS METDI4521 NC_012988.1 4419524 4420342 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; UspA domain protein, putative universal stress response protein complement(4419524..4420342) Methylobacterium extorquens DM4 8193943 YP_003069973.1 CDS METDI4525 NC_012988.1 4421403 4421780 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4421403..4421780) Methylobacterium extorquens DM4 8193946 YP_003069974.1 CDS METDI4526 NC_012988.1 4421777 4422154 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4421777..4422154) Methylobacterium extorquens DM4 8193947 YP_003069975.1 CDS METDI4527 NC_012988.1 4422222 4422461 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative biotin/lipoyl attachment domain complement(4422222..4422461) Methylobacterium extorquens DM4 8193948 YP_003069976.1 CDS METDI4528 NC_012988.1 4422656 4423174 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4422656..4423174 Methylobacterium extorquens DM4 8193949 YP_003069977.1 CDS METDI4530 NC_012988.1 4423258 4423473 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4423258..4423473 Methylobacterium extorquens DM4 8193950 YP_003069978.1 CDS METDI4529 NC_012988.1 4423484 4423741 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4423484..4423741 Methylobacterium extorquens DM4 8193952 YP_003069979.1 CDS METDI4531 NC_012988.1 4423738 4425069 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Manganese transport protein mntH 4423738..4425069 Methylobacterium extorquens DM4 8193951 YP_003069980.1 CDS METDI4532 NC_012988.1 4425135 4425587 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4425135..4425587 Methylobacterium extorquens DM4 8193953 YP_003069981.1 CDS METDI4534 NC_012988.1 4425637 4426284 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 4425637..4426284 Methylobacterium extorquens DM4 8193954 YP_003069982.1 CDS METDI4535 NC_012988.1 4426370 4427179 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Universal stress protein, UspA 4426370..4427179 Methylobacterium extorquens DM4 8193955 YP_003069983.1 CDS METDI4536 NC_012988.1 4427222 4427455 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4427222..4427455 Methylobacterium extorquens DM4 8193956 YP_003069984.1 CDS METDI4537 NC_012988.1 4427521 4428180 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4427521..4428180) Methylobacterium extorquens DM4 8193957 YP_003069985.1 CDS METDI4538 NC_012988.1 4428398 4428730 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cytochrome c, class I complement(4428398..4428730) Methylobacterium extorquens DM4 8193958 YP_003069986.1 CDS METDI4539 NC_012988.1 4428730 4429545 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative universal stress protein, UspA-like complement(4428730..4429545) Methylobacterium extorquens DM4 8193959 YP_003069987.1 CDS METDI4540 NC_012988.1 4429667 4430650 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Zn-containing alcohol dehydrogenase (adh) complement(4429667..4430650) Methylobacterium extorquens DM4 8193960 YP_003069988.1 CDS METDI4541 NC_012988.1 4430660 4431307 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4430660..4431307) Methylobacterium extorquens DM4 8193961 YP_003069989.1 CDS METDI4542 NC_012988.1 4431337 4431537 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4431337..4431537) Methylobacterium extorquens DM4 8193962 YP_003069990.1 CDS xfp NC_012988.1 4431665 4434211 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11292814, 11823225; Product type e : enzyme; putative phosphoketolase 4431665..4434211 Methylobacterium extorquens DM4 8193963 YP_003069991.1 CDS METDI4544 NC_012988.1 4434359 4435222 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetate kinase (partial) 4434359..4435222 Methylobacterium extorquens DM4 8196341 YP_003069992.1 CDS METDI4545 NC_012988.1 4435427 4435915 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4435427..4435915 Methylobacterium extorquens DM4 8193964 YP_003069993.1 CDS aqpZ NC_012988.1 4435958 4436704 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; aquaporin 4435958..4436704 Methylobacterium extorquens DM4 8193965 YP_003069994.1 CDS METDI4547 NC_012988.1 4436754 4436930 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4436754..4436930) Methylobacterium extorquens DM4 8195080 YP_003069995.1 CDS METDI4548 NC_012988.1 4436927 4437415 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4436927..4437415) Methylobacterium extorquens DM4 8193966 YP_003069996.1 CDS METDI4549 NC_012988.1 4437427 4438077 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4437427..4438077) Methylobacterium extorquens DM4 8193967 YP_003069997.1 CDS METDI4550 NC_012988.1 4438130 4438474 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4438130..4438474) Methylobacterium extorquens DM4 8193968 YP_003069998.1 CDS METDI4551 NC_012988.1 4438632 4439018 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4438632..4439018 Methylobacterium extorquens DM4 8193969 YP_003069999.1 CDS METDI4552 NC_012988.1 4439265 4439660 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4439265..4439660 Methylobacterium extorquens DM4 8193970 YP_003070000.1 CDS METDI4553 NC_012988.1 4439657 4439884 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4439657..4439884 Methylobacterium extorquens DM4 8193971 YP_003070001.1 CDS METDI4554 NC_012988.1 4440013 4442757 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative cation-transporting ATPase 4440013..4442757 Methylobacterium extorquens DM4 8193972 YP_003070002.1 CDS METDI4555 NC_012988.1 4442865 4443725 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4442865..4443725 Methylobacterium extorquens DM4 8193973 YP_003070003.1 CDS fixK2 NC_012988.1 4444067 4444753 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family [ complement(4444067..4444753) Methylobacterium extorquens DM4 8193974 YP_003070004.1 CDS METDI4557 NC_012988.1 4444877 4445101 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4444877..4445101) Methylobacterium extorquens DM4 8195381 YP_003070005.1 CDS METDI4558 NC_012988.1 4445285 4445602 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4445285..4445602 Methylobacterium extorquens DM4 8193975 YP_003070006.1 CDS METDI4559 NC_012988.1 4445662 4446054 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4445662..4446054 Methylobacterium extorquens DM4 8193976 YP_003070007.1 CDS METDI4560 NC_012988.1 4446195 4446584 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12597275, 2000090, 7968919, 9748464; Product type pr : putative regulator; putative two component response regulator (FixJ domain-like) complement(4446195..4446584) Methylobacterium extorquens DM4 8193977 YP_003070008.1 CDS fixJ NC_012988.1 4446674 4447282 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12597275, 2000090; Product type r : regulator; two component transcriptional regulator, LuxR family; putative nitrogen fixation transcriptional regulator FixJ complement(4446674..4447282) Methylobacterium extorquens DM4 8193978 YP_003070009.1 CDS fixL NC_012988.1 4447272 4448822 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; two component low oxygen sensor histidine kinase with PAS domains; FixL complement(4447272..4448822) Methylobacterium extorquens DM4 8195379 YP_003070010.1 CDS METDI4563 NC_012988.1 4449145 4450005 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4449145..4450005 Methylobacterium extorquens DM4 8195384 YP_003070011.1 CDS METDI4564 NC_012988.1 4450321 4450650 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cytochrome c, class I complement(4450321..4450650) Methylobacterium extorquens DM4 8193979 YP_003070012.1 CDS METDI4565 NC_012988.1 4450650 4451462 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Universal stress protein, UspA complement(4450650..4451462) Methylobacterium extorquens DM4 8193980 YP_003070013.1 CDS METDI4566 NC_012988.1 4451557 4453479 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Cation-transporting ATPase complement(4451557..4453479) Methylobacterium extorquens DM4 8193981 YP_003070014.1 CDS METDI4567 NC_012988.1 4453999 4454364 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4453999..4454364) Methylobacterium extorquens DM4 8193982 YP_003070015.1 CDS METDI4569 NC_012988.1 4454661 4454996 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4454661..4454996 Methylobacterium extorquens DM4 8193983 YP_003070016.1 CDS METDI4570 NC_012988.1 4455951 4456880 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex17, IS110 family complement(4455951..4456880) Methylobacterium extorquens DM4 8196244 YP_003070017.1 CDS METDI4571 NC_012988.1 4457245 4457457 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4457245..4457457) Methylobacterium extorquens DM4 8193985 YP_003070018.1 CDS METDI4572 NC_012988.1 4457695 4457946 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4457695..4457946) Methylobacterium extorquens DM4 8193986 YP_003070019.1 CDS METDI4573 NC_012988.1 4457945 4458163 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4457945..4458163 Methylobacterium extorquens DM4 8193987 YP_003070020.1 CDS METDI4574 NC_012988.1 4458160 4458483 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4458160..4458483 Methylobacterium extorquens DM4 8193988 YP_003070021.1 CDS METDI4575 NC_012988.1 4458579 4459625 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4458579..4459625) Methylobacterium extorquens DM4 8193989 YP_003070022.1 CDS METDI4576 NC_012988.1 4459770 4460477 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4459770..4460477) Methylobacterium extorquens DM4 8193990 YP_003070023.1 CDS METDI4577 NC_012988.1 4460570 4461274 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4460570..4461274) Methylobacterium extorquens DM4 8193991 YP_003070024.1 CDS METDI4578 NC_012988.1 4461664 4462026 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4461664..4462026 Methylobacterium extorquens DM4 8193992 YP_003070025.1 CDS METDI4579 NC_012988.1 4462178 4462423 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4462178..4462423 Methylobacterium extorquens DM4 8193993 YP_003070026.1 CDS METDI4580 NC_012988.1 4462750 4462989 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4462750..4462989 Methylobacterium extorquens DM4 8193994 YP_003070027.1 CDS METDI4581 NC_012988.1 4463289 4463744 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4463289..4463744 Methylobacterium extorquens DM4 8193995 YP_003070028.1 CDS METDI4582 NC_012988.1 4464196 4464495 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4464196..4464495 Methylobacterium extorquens DM4 8193996 YP_003070029.1 CDS METDI4583 NC_012988.1 4464663 4464854 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4464663..4464854) Methylobacterium extorquens DM4 8193997 YP_003070030.1 CDS METDI4584 NC_012988.1 4465028 4465234 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4465028..4465234 Methylobacterium extorquens DM4 8193998 YP_003070031.1 CDS METDI4585 NC_012988.1 4465285 4465488 R Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein complement(4465285..4465488) Methylobacterium extorquens DM4 8193999 YP_003070032.1 CDS METDI4586 NC_012988.1 4465590 4465898 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4465590..4465898) Methylobacterium extorquens DM4 8194000 YP_003070033.1 CDS mntR NC_012988.1 4465967 4466434 R Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR complement(4465967..4466434) Methylobacterium extorquens DM4 8194001 YP_003070034.1 CDS mntH NC_012988.1 4466852 4468186 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10712688, 10844693, 20177822, 20305051; Product type t : transporter; manganese transport protein mntH 4466852..4468186 Methylobacterium extorquens DM4 8195701 YP_003070035.1 CDS METDI4589 NC_012988.1 4468199 4469089 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family complement(4468199..4469089) Methylobacterium extorquens DM4 8195700 YP_003070036.1 CDS METDI4590 NC_012988.1 4469266 4470591 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Sodium/sulphate symporter 4469266..4470591 Methylobacterium extorquens DM4 8194002 YP_003070037.1 CDS sdhC NC_012988.1 4470719 4471120 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12730156; Product type e : enzyme; succinate dehydrogenase, cytochrome b556 subunit 4470719..4471120 Methylobacterium extorquens DM4 8194003 YP_003070038.1 CDS sdhD NC_012988.1 4471129 4471548 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12730156; Product type e : enzyme; succinate dehydrogenase, membrane anchor subunit 4471129..4471548 Methylobacterium extorquens DM4 8196103 YP_003070039.1 CDS sdhA NC_012988.1 4471578 4473395 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 4471578..4473395 Methylobacterium extorquens DM4 8196104 YP_003070040.1 CDS sdhB NC_012988.1 4474057 4474881 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12730156; Product type e : enzyme; succinate dehydrogenase, iron-sulfur subunit 4474057..4474881 Methylobacterium extorquens DM4 8196101 YP_003070041.1 CDS METDI4596 NC_012988.1 4475125 4475685 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4475125..4475685 Methylobacterium extorquens DM4 8196102 YP_003070042.1 CDS METDI4597 NC_012988.1 4475690 4477462 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4475690..4477462) Methylobacterium extorquens DM4 8194004 YP_003070043.1 CDS kdsD NC_012988.1 4477722 4478744 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12805358; Product type e : enzyme; Arabinose-5-phosphate isomerase 4477722..4478744 Methylobacterium extorquens DM4 8194005 YP_003070044.1 CDS METDI4599 NC_012988.1 4482625 4483068 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4482625..4483068) Methylobacterium extorquens DM4 8195621 YP_003070045.1 CDS METDI4600 NC_012988.1 4483500 4484264 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1743516; Product type e : enzyme; Enoyl-CoA hydratase/isomerase family protein 4483500..4484264 Methylobacterium extorquens DM4 8194006 YP_003070046.1 CDS METDI4601 NC_012988.1 4484306 4485124 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR 4484306..4485124 Methylobacterium extorquens DM4 8194007 YP_003070047.1 CDS METDI4602 NC_012988.1 4485121 4485975 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR 4485121..4485975 Methylobacterium extorquens DM4 8194008 YP_003070048.1 CDS METDI4603 NC_012988.1 4486001 4487005 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative magnesium/cobalt transport protein 4486001..4487005 Methylobacterium extorquens DM4 8194009 YP_003070049.1 CDS METDI4604 NC_012988.1 4487216 4487758 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4487216..4487758 Methylobacterium extorquens DM4 8194010 YP_003070050.1 CDS METDI4605 NC_012988.1 4487915 4488088 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4487915..4488088) Methylobacterium extorquens DM4 8194011 YP_003070051.1 CDS METDI4606 NC_012988.1 4488264 4489961 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; methyl-accepting chemotaxis sensory transducer 4488264..4489961 Methylobacterium extorquens DM4 8194012 YP_003070052.1 CDS METDI4607 NC_012988.1 4490063 4490344 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4490063..4490344) Methylobacterium extorquens DM4 8194013 YP_003070053.1 CDS METDI4608 NC_012988.1 4490941 4491279 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4490941..4491279 Methylobacterium extorquens DM4 8194014 YP_003070054.1 CDS METDI4609 NC_012988.1 4491470 4491721 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4491470..4491721) Methylobacterium extorquens DM4 8194015 YP_003070055.1 CDS METDI4610 NC_012988.1 4492027 4492425 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4492027..4492425) Methylobacterium extorquens DM4 8194016 YP_003070056.1 CDS METDI4611 NC_012988.1 4492530 4493378 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family 4492530..4493378 Methylobacterium extorquens DM4 8194017 YP_003070057.1 CDS METDI4612 NC_012988.1 4493576 4493770 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4493576..4493770 Methylobacterium extorquens DM4 8194018 YP_003070058.1 CDS METDI4613 NC_012988.1 4493755 4495830 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hybrid histidine kinase: Domains: GAF, Histidine Kinase, ATPase and CheY-like 4493755..4495830 Methylobacterium extorquens DM4 8194019 YP_003070059.1 CDS METDI4614 NC_012988.1 4496047 4496565 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4496047..4496565 Methylobacterium extorquens DM4 8194020 YP_003070060.1 CDS METDI4615 NC_012988.1 4496677 4497183 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4496677..4497183 Methylobacterium extorquens DM4 8194021 YP_003070061.1 CDS METDI4616 NC_012988.1 4497249 4497965 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11557893; Product type pe : putative enzyme; putative Endonuclease III (DNA-(apurinic or apyrimidinic site) lyase) 4497249..4497965 Methylobacterium extorquens DM4 8194022 YP_003070062.1 CDS METDI4617 NC_012988.1 4498074 4498994 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(4498074..4498994) Methylobacterium extorquens DM4 8194023 YP_003070063.1 CDS METDI4618 NC_012988.1 4499118 4499690 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4499118..4499690 Methylobacterium extorquens DM4 8194024 YP_003070064.1 CDS METDI4619 NC_012988.1 4499937 4500773 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7632719, 8344520; Product type e : enzyme; non-heme haloperoxidase 4499937..4500773 Methylobacterium extorquens DM4 8194025 YP_003070065.1 CDS METDI4620 NC_012988.1 4500794 4501285 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4500794..4501285) Methylobacterium extorquens DM4 8194026 YP_003070066.1 CDS METDI4621 NC_012988.1 4501478 4501675 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4501478..4501675) Methylobacterium extorquens DM4 8194027 YP_003070067.1 CDS METDI4622 NC_012988.1 4501688 4502206 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4501688..4502206 Methylobacterium extorquens DM4 8194028 YP_003070068.1 CDS METDI4623 NC_012988.1 4502267 4502485 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8392137; hypothetical protein 4502267..4502485 Methylobacterium extorquens DM4 8194029 YP_003070069.1 CDS METDI4624 NC_012988.1 4502727 4502960 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4502727..4502960 Methylobacterium extorquens DM4 8194030 YP_003070070.1 CDS METDI4625 NC_012988.1 4502966 4503214 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4502966..4503214 Methylobacterium extorquens DM4 8194031 YP_003070071.1 CDS modB NC_012988.1 4503300 4504025 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7665460, 8564363; Product type t : transporter; molybdate transporter, membrane component of ABC transporter 4503300..4504025 Methylobacterium extorquens DM4 8194032 YP_003070072.1 CDS METDI4627 NC_012988.1 4504248 4504628 D Evidence 5 : No homology to any previously reported sequences; Product type pt : putative transporter; hypothetical protein 4504248..4504628 Methylobacterium extorquens DM4 8195711 YP_003070073.1 CDS METDI4628 NC_012988.1 4504701 4505357 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(4504701..4505357) Methylobacterium extorquens DM4 8194033 YP_003070074.1 CDS modC NC_012988.1 4505620 4506714 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7665518, 8384683; Product type t : transporter; molybdate transporter, ATP-binding component of ABC transporter 4505620..4506714 Methylobacterium extorquens DM4 8194034 YP_003070075.1 CDS METDI4630 NC_012988.1 4507349 4507978 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4507349..4507978 Methylobacterium extorquens DM4 8195714 YP_003070076.1 CDS pdxA NC_012988.1 4508002 4509051 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 4-hydroxythreonine-4-phosphate dehydrogenase (4-(phosphohydroxy)-L-threonine dehydrogenase) 4508002..4509051 Methylobacterium extorquens DM4 8194035 YP_003070077.1 CDS ksgA NC_012988.1 4509060 4509950 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 4509060..4509950 Methylobacterium extorquens DM4 8195840 YP_003070078.1 CDS METDI4633 NC_012988.1 4510603 4511649 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4510603..4511649) Methylobacterium extorquens DM4 8194036 YP_003070079.1 CDS METDI4636 NC_012988.1 4513161 4513376 D Evidence 6 : Doubtful CDS; hypothetical protein 4513161..4513376 Methylobacterium extorquens DM4 8194039 YP_003070080.1 CDS METDI4637 NC_012988.1 4513434 4514477 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase complement(4513434..4514477) Methylobacterium extorquens DM4 8194040 YP_003070081.1 CDS METDI4638 NC_012988.1 4514715 4516220 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sulfate transporter complement(4514715..4516220) Methylobacterium extorquens DM4 8194041 YP_003070082.1 CDS METDI4639 NC_012988.1 4516399 4517115 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative Inner membrane protein yohK complement(4516399..4517115) Methylobacterium extorquens DM4 8194042 YP_003070083.1 CDS METDI4640 NC_012988.1 4517112 4517498 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative Holin-like protein cidA 1 complement(4517112..4517498) Methylobacterium extorquens DM4 8194043 YP_003070084.1 CDS METDI4641 NC_012988.1 4517625 4518101 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4517625..4518101) Methylobacterium extorquens DM4 8194044 YP_003070085.1 CDS METDI4642 NC_012988.1 4518346 4519080 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4518346..4519080) Methylobacterium extorquens DM4 8194045 YP_003070086.1 CDS METDI4643 NC_012988.1 4519108 4521738 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative organic solvent tolerance protein complement(4519108..4521738) Methylobacterium extorquens DM4 8194046 YP_003070087.1 CDS METDI4644 NC_012988.1 4521787 4522875 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative permease complement(4521787..4522875) Methylobacterium extorquens DM4 8194047 YP_003070088.1 CDS METDI4645 NC_012988.1 4522886 4524055 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative permease complement(4522886..4524055) Methylobacterium extorquens DM4 8194048 YP_003070089.1 CDS METDI4646 NC_012988.1 4524347 4525840 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; cytosol aminopeptidase (putative leucine aminopeptidase) 4524347..4525840 Methylobacterium extorquens DM4 8194049 YP_003070090.1 CDS METDI4647 NC_012988.1 4525837 4526637 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4525837..4526637 Methylobacterium extorquens DM4 8194050 YP_003070091.1 CDS fadD NC_012988.1 4526737 4528473 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12034706, 8107670; Product type e : enzyme; acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase) 4526737..4528473 Methylobacterium extorquens DM4 8194051 YP_003070092.1 CDS METDI4649 NC_012988.1 4528478 4528627 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4528478..4528627) Methylobacterium extorquens DM4 8195351 YP_003070093.1 CDS METDI4650 NC_012988.1 4528697 4528966 D Evidence 6 : Doubtful CDS; hypothetical protein 4528697..4528966 Methylobacterium extorquens DM4 8194052 YP_003070094.1 CDS METDI4651 NC_012988.1 4528933 4530114 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; putative MscS mechanosensitive ion channel 4528933..4530114 Methylobacterium extorquens DM4 8194053 YP_003070095.1 CDS METDI4652 NC_012988.1 4530180 4530977 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thioredoxin domain protein precursor complement(4530180..4530977) Methylobacterium extorquens DM4 8194054 YP_003070096.1 CDS METDI4653 NC_012988.1 4531257 4532300 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal-dependent phosphohydrolase (HD domain) 4531257..4532300 Methylobacterium extorquens DM4 8194055 YP_003070097.1 CDS METDI4654 NC_012988.1 4532426 4533739 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1406271, 2451538, 2456446, 3017428; Product type pt : putative transporter; putative phosphate-selective porin O and P precursor 4532426..4533739 Methylobacterium extorquens DM4 8194056 YP_003070098.1 CDS METDI4655 NC_012988.1 4533818 4534981 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aspartate aminotransferase 4533818..4534981 Methylobacterium extorquens DM4 8194057 YP_003070099.1 CDS METDI4656 NC_012988.1 4535015 4535908 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4535015..4535908) Methylobacterium extorquens DM4 8194058 YP_003070100.1 CDS METDI4657 NC_012988.1 4536043 4536330 D Evidence 6 : Doubtful CDS; hypothetical protein 4536043..4536330 Methylobacterium extorquens DM4 8194059 YP_003070101.1 CDS METDI4658 NC_012988.1 4536403 4539564 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10362534, 11328869, 8415644; Product type pe : putative enzyme; putative ribonuclease E or G complement(4536403..4539564) Methylobacterium extorquens DM4 8194060 YP_003070102.1 CDS METDI4659 NC_012988.1 4540251 4540436 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4540251..4540436 Methylobacterium extorquens DM4 8194061 YP_003070103.1 CDS METDI4660 NC_012988.1 4540627 4541958 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative N-acetylmuramoyl-L-alanine amidase amiC precursor 4540627..4541958 Methylobacterium extorquens DM4 8194062 YP_003070104.1 CDS METDI4661 NC_012988.1 4542283 4544700 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative bifunctional N-terminal transglycosylase/C-terminal transpeptidase precursor; 1A family penicillin-binding protein 4542283..4544700 Methylobacterium extorquens DM4 8194063 YP_003070105.1 CDS METDI4662 NC_012988.1 4544992 4546104 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Alkanesulfonate monooxygenase 4544992..4546104 Methylobacterium extorquens DM4 8194064 YP_003070106.1 CDS METDI4663 NC_012988.1 4546289 4547548 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15661012; Product type pe : putative enzyme; acyl-CoA dehydrogenase 4546289..4547548 Methylobacterium extorquens DM4 8194065 YP_003070107.1 CDS METDI4664 NC_012988.1 4547686 4548357 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, 2Fe-2S subunit 4547686..4548357 Methylobacterium extorquens DM4 8194066 YP_003070108.1 CDS METDI4665 NC_012988.1 4548371 4549345 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, FAD-binding subunit 4548371..4549345 Methylobacterium extorquens DM4 8194067 YP_003070109.1 CDS METDI4666 NC_012988.1 4549357 4551594 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; oxidoreductase, molybdopterin-binding subunit 4549357..4551594 Methylobacterium extorquens DM4 8194068 YP_003070110.1 CDS METDI4667 NC_012988.1 4551722 4551976 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4551722..4551976 Methylobacterium extorquens DM4 8194069 YP_003070111.1 CDS yieG NC_012988.1 4552086 4553426 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Xanthine/uracil/vitamin C permease:Sulphate transporter 4552086..4553426 Methylobacterium extorquens DM4 8194070 YP_003070112.1 CDS METDI4669 NC_012988.1 4553570 4553764 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4553570..4553764 Methylobacterium extorquens DM4 8196369 YP_003070113.1 CDS METDI4670 NC_012988.1 4553753 4554784 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative monooxygenase with ATPase activity, luciferase family protein complement(4553753..4554784) Methylobacterium extorquens DM4 8194071 YP_003070114.1 CDS METDI4671 NC_012988.1 4555367 4555591 D Evidence 6 : Doubtful CDS; hypothetical protein 4555367..4555591 Methylobacterium extorquens DM4 8194072 YP_003070115.1 CDS METDI4672 NC_012988.1 4556059 4556265 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4556059..4556265) Methylobacterium extorquens DM4 8194073 YP_003070116.1 CDS METDI4673 NC_012988.1 4556489 4556998 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NADPH-dependent FMN reductase, putative ArsH protein complement(4556489..4556998) Methylobacterium extorquens DM4 8194074 YP_003070117.1 CDS METDI4674 NC_012988.1 4557169 4558350 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4557169..4558350) Methylobacterium extorquens DM4 8194075 YP_003070118.1 CDS METDI4675 NC_012988.1 4558319 4558567 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4558319..4558567 Methylobacterium extorquens DM4 8194076 YP_003070119.1 CDS mdoD NC_012988.1 4558752 4560398 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 4558752..4560398 Methylobacterium extorquens DM4 8194077 YP_003070120.1 CDS METDI4677 NC_012988.1 4560450 4562636 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 4560450..4562636 Methylobacterium extorquens DM4 8194078 YP_003070121.1 CDS METDI4678 NC_012988.1 4563127 4563309 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4563127..4563309 Methylobacterium extorquens DM4 8196260 YP_003070122.1 CDS METDI4679 NC_012988.1 4563553 4563768 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4563553..4563768 Methylobacterium extorquens DM4 8194080 YP_003070123.1 CDS METDI4680 NC_012988.1 4563844 4564635 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4563844..4564635) Methylobacterium extorquens DM4 8194081 YP_003070124.1 CDS METDI4681 NC_012988.1 4564666 4564887 R Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein complement(4564666..4564887) Methylobacterium extorquens DM4 8194082 YP_003070125.1 CDS METDI4682 NC_012988.1 4564959 4565126 D Evidence 6 : Doubtful CDS; hypothetical protein 4564959..4565126 Methylobacterium extorquens DM4 8194083 YP_003070126.1 CDS METDI4683 NC_012988.1 4565111 4565326 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4565111..4565326) Methylobacterium extorquens DM4 8194084 YP_003070127.1 CDS METDI4684 NC_012988.1 4565450 4567285 R catalyzes the hydrolysis of allophanate; allophanate hydrolase complement(4565450..4567285) Methylobacterium extorquens DM4 8194085 YP_003070128.1 CDS METDI4685 NC_012988.1 4567393 4567512 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4567393..4567512) Methylobacterium extorquens DM4 8194086 YP_003070129.1 CDS METDI4686 NC_012988.1 4567597 4571127 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15090492; Product type e : enzyme; ATP-dependent urea carboxylase complement(4567597..4571127) Methylobacterium extorquens DM4 8194087 YP_003070130.1 CDS METDI4687 NC_012988.1 4571132 4571752 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4571132..4571752) Methylobacterium extorquens DM4 8194088 YP_003070131.1 CDS METDI4688 NC_012988.1 4571767 4572573 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4571767..4572573) Methylobacterium extorquens DM4 8194089 YP_003070132.1 CDS METDI4689 NC_012988.1 4572736 4573107 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4572736..4573107) Methylobacterium extorquens DM4 8194090 YP_003070133.1 CDS METDI4690 NC_012988.1 4573120 4574493 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356885; Product type pe : putative enzyme; putative glutamine synthetase III (glnT) complement(4573120..4574493) Methylobacterium extorquens DM4 8194091 YP_003070134.1 CDS METDI4691 NC_012988.1 4574495 4575295 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9563845; Product type e : enzyme; Creatininase complement(4574495..4575295) Methylobacterium extorquens DM4 8194092 YP_003070135.1 CDS METDI4692 NC_012988.1 4575292 4576242 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, ATPase complement(4575292..4576242) Methylobacterium extorquens DM4 8194093 YP_003070136.1 CDS METDI4693 NC_012988.1 4576239 4577300 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, permease complement(4576239..4577300) Methylobacterium extorquens DM4 8194094 YP_003070137.1 CDS METDI4694 NC_012988.1 4577311 4578321 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter, periplasmic protein complement(4577311..4578321) Methylobacterium extorquens DM4 8194095 YP_003070138.1 CDS proV NC_012988.1 4579325 4580653 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; glycine/betaine/proline transporter, ATP-binding component of ABC transporter 4579325..4580653 Methylobacterium extorquens DM4 8195034 YP_003070139.1 CDS opuAB NC_012988.1 4580569 4581420 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; glycine/betaine/proline transporter, membrane component of ABC transporter 4580569..4581420 Methylobacterium extorquens DM4 8195905 YP_003070140.1 CDS proX NC_012988.1 4581606 4582442 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; glycine/betaine/proline transporter, Substrate-binding periplasmic component of ABC transporter 4581606..4582442 Methylobacterium extorquens DM4 8195812 YP_003070141.1 CDS METDI4698 NC_012988.1 4582523 4583872 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4582523..4583872 Methylobacterium extorquens DM4 8195906 YP_003070142.1 CDS METDI4699 NC_012988.1 4584066 4585010 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, AraC family complement(4584066..4585010) Methylobacterium extorquens DM4 8194097 YP_003070143.1 CDS soxB NC_012988.1 4585534 4586787 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7692961, 8611516, 9485355; Product type e : enzyme; sarcosine oxidase, beta subunit 4585534..4586787 Methylobacterium extorquens DM4 8194098 YP_003070144.1 CDS soxD NC_012988.1 4586807 4587103 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15914915, 7543100; Product type e : enzyme; sarcosine oxidase, delta subunit 4586807..4587103 Methylobacterium extorquens DM4 8196128 YP_003070145.1 CDS soxA NC_012988.1 4587105 4590092 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sarcosine oxidase, alpha subunit 4587105..4590092 Methylobacterium extorquens DM4 8196131 YP_003070146.1 CDS soxG NC_012988.1 4590085 4590675 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; sarcosine oxidase, gamma subunit 4590085..4590675 Methylobacterium extorquens DM4 8196125 YP_003070147.1 CDS sdaB NC_012988.1 4590818 4592179 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; L-serine deaminase 4590818..4592179 Methylobacterium extorquens DM4 8196133 YP_003070148.1 CDS METDI4705 NC_012988.1 4592576 4592830 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4592576..4592830 Methylobacterium extorquens DM4 8196100 YP_003070149.1 CDS METDI4706 NC_012988.1 4592837 4593346 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4592837..4593346) Methylobacterium extorquens DM4 8194099 YP_003070150.1 CDS METDI4707 NC_012988.1 4593360 4594154 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative electron transfer flavoprotein, beta subunit complement(4593360..4594154) Methylobacterium extorquens DM4 8194100 YP_003070151.1 CDS METDI4708 NC_012988.1 4594151 4595371 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative electron transfer flavoprotein alpha subunit complement(4594151..4595371) Methylobacterium extorquens DM4 8194101 YP_003070152.1 CDS METDI4709 NC_012988.1 4595368 4597269 R Evidence 2b : Function of strongly homologous gene; Product type c : carrier; Iron-sulfur cluster-binding protein complement(4595368..4597269) Methylobacterium extorquens DM4 8194102 YP_003070153.1 CDS METDI4710 NC_012988.1 4597557 4599599 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9758825; Product type e : enzyme; NADH:flavin oxidoreductase/NADH oxidase complement(4597557..4599599) Methylobacterium extorquens DM4 8194103 YP_003070154.1 CDS METDI4711 NC_012988.1 4599662 4600789 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Iron-sulfur cluster-binding protein, putative ferredoxin oxidoreductase protein complement(4599662..4600789) Methylobacterium extorquens DM4 8194104 YP_003070155.1 CDS METDI4712 NC_012988.1 4600793 4602052 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Iron-sulphur Rieske protein complement(4600793..4602052) Methylobacterium extorquens DM4 8194105 YP_003070156.1 CDS METDI4713 NC_012988.1 4602177 4602983 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16901339; Product type pe : putative enzyme; putative L-histidinol-phosphate phosphatase (hisN) complement(4602177..4602983) Methylobacterium extorquens DM4 8194106 YP_003070157.1 CDS METDI4714 NC_012988.1 4602987 4603922 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative choline/ethanolamine kinase complement(4602987..4603922) Methylobacterium extorquens DM4 8194107 YP_003070158.1 CDS METDI4715 NC_012988.1 4604134 4605114 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4604134..4605114) Methylobacterium extorquens DM4 8194108 YP_003070159.1 CDS METDI4716 NC_012988.1 4605111 4606403 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(4605111..4606403) Methylobacterium extorquens DM4 8194109 YP_003070160.1 CDS METDI4717 NC_012988.1 4606436 4608274 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATP-binding protein; putative peptide transporter complement(4606436..4608274) Methylobacterium extorquens DM4 8194110 YP_003070161.1 CDS METDI4718 NC_012988.1 4608274 4609197 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Oligopeptide/dipeptide ABC transporter, membrane component (ddpC-like) complement(4608274..4609197) Methylobacterium extorquens DM4 8194111 YP_003070162.1 CDS METDI4719 NC_012988.1 4609197 4610177 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Oligopeptide/dipeptide ABC transporter, membrane component complement(4609197..4610177) Methylobacterium extorquens DM4 8194112 YP_003070163.1 CDS METDI4720 NC_012988.1 4610288 4611859 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, substrate-binding protein (tat pathway signal) complement(4610288..4611859) Methylobacterium extorquens DM4 8194113 YP_003070164.1 CDS METDI4721 NC_012988.1 4612192 4614711 R Evidence 2b : Function of strongly homologous gene; Product type prc : putative receptor; tonB-dependent siderophore receptor protein complement(4612192..4614711) Methylobacterium extorquens DM4 8194114 YP_003070165.1 CDS METDI4722 NC_012988.1 4614882 4615847 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2254251, 8026465; Product type pr : putative regulator; putative FecR, iron siderophore sensor protein complement(4614882..4615847) Methylobacterium extorquens DM4 8194115 YP_003070166.1 CDS METDI4723 NC_012988.1 4615946 4616467 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor complement(4615946..4616467) Methylobacterium extorquens DM4 8194116 YP_003070167.1 CDS METDI4724 NC_012988.1 4617348 4619132 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; Siderophore synthetase component 4617348..4619132 Methylobacterium extorquens DM4 8194117 YP_003070168.1 CDS METDI4725 NC_012988.1 4619137 4622097 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative non-ribosomal peptide synthetase, putative acyl-CoA ligase for activation during siderophore synthesis 4619137..4622097 Methylobacterium extorquens DM4 8194118 YP_003070169.1 CDS METDI4726 NC_012988.1 4622094 4623401 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4622094..4623401 Methylobacterium extorquens DM4 8194119 YP_003070170.1 CDS METDI4727 NC_012988.1 4623398 4624234 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4623398..4624234 Methylobacterium extorquens DM4 8194120 YP_003070171.1 CDS METDI4728 NC_012988.1 4624263 4624541 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4624263..4624541 Methylobacterium extorquens DM4 8194121 YP_003070172.1 CDS METDI4729 NC_012988.1 4624830 4625330 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; GCN5-related N-acetyltransferase 4624830..4625330 Methylobacterium extorquens DM4 8194122 YP_003070173.1 CDS METDI4730 NC_012988.1 4625498 4626175 D Evidence 5 : No homology to any previously reported sequences; PubMedId : 11259647; hypothetical protein 4625498..4626175 Methylobacterium extorquens DM4 8194123 YP_003070174.1 CDS METDI4731 NC_012988.1 4626980 4627753 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, TetR family complement(4626980..4627753) Methylobacterium extorquens DM4 8194124 YP_003070175.1 CDS proC NC_012988.1 4627824 4628657 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2107123, 2199815; Product type e : enzyme; pyrroline-5-carboxylate reductase complement(4627824..4628657) Methylobacterium extorquens DM4 8194125 YP_003070176.1 CDS METDI4733 NC_012988.1 4628739 4629245 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4628739..4629245) Methylobacterium extorquens DM4 8195903 YP_003070177.1 CDS METDI4734 NC_012988.1 4629704 4629985 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4629704..4629985) Methylobacterium extorquens DM4 8194126 YP_003070178.1 CDS ompR NC_012988.1 4630228 4630953 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10464234, 2845093, 2997120, 3010044, 6292199, 91175693, 92165726, 93287101; Product type r : regulator; response regulator in two-component regulatory system with EnvZ, regulates ompF and ompC expression (OmpR family) 4630228..4630953 Methylobacterium extorquens DM4 8194127 YP_003070179.1 CDS METDI4736 NC_012988.1 4630950 4632428 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative signal transduction histidine kinase precursor 4630950..4632428 Methylobacterium extorquens DM4 8195809 YP_003070180.1 CDS METDI4737 NC_012988.1 4632629 4633801 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF) 4632629..4633801 Methylobacterium extorquens DM4 8194128 YP_003070181.1 CDS METDI4738 NC_012988.1 4633930 4634586 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(4633930..4634586) Methylobacterium extorquens DM4 8194129 YP_003070182.1 CDS METDI4739 NC_012988.1 4634937 4636151 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10217786, 11114905, 11267773, 11410342, 12081972, 12813072, 15256572, 8550; Product type e : enzyme; intracellular PHB depolymerase, polyhydroxyalkanoate depolymerase 4634937..4636151 Methylobacterium extorquens DM4 8194130 YP_003070183.1 CDS rpsU NC_012988.1 4636586 4636903 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 4636586..4636903 Methylobacterium extorquens DM4 8194131 YP_003070184.1 CDS METDI4741 NC_012988.1 4637002 4637391 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator; (CheY-like protein) complement(4637002..4637391) Methylobacterium extorquens DM4 8196071 YP_003070185.1 CDS METDI4742 NC_012988.1 4637671 4638456 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aminohydrolase/amidotransferase 4637671..4638456 Methylobacterium extorquens DM4 8194132 YP_003070186.1 CDS METDI4743 NC_012988.1 4638607 4639398 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4638607..4639398 Methylobacterium extorquens DM4 8194133 YP_003070187.1 CDS mcd NC_012988.1 4639427 4640473 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16856937, 17548827, 18065535; Product type e : enzyme; mesaconyl-CoA hydratase complement(4639427..4640473) Methylobacterium extorquens DM4 8194134 YP_003070188.1 CDS METDI4745 NC_012988.1 4640667 4640957 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4640667..4640957) Methylobacterium extorquens DM4 8195665 YP_003070189.1 CDS METDI4746 NC_012988.1 4641261 4642274 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative integrase 4641261..4642274 Methylobacterium extorquens DM4 8196215 YP_003070190.1 CDS METDI4747 NC_012988.1 4643046 4644587 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enzyme with a serine protease-like domain complement(4643046..4644587) Methylobacterium extorquens DM4 8194136 YP_003070191.1 CDS METDI4749 NC_012988.1 4645655 4646959 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4645655..4646959 Methylobacterium extorquens DM4 8194137 YP_003070192.1 CDS METDI4750 NC_012988.1 4647081 4647392 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4647081..4647392 Methylobacterium extorquens DM4 8194138 YP_003070193.1 CDS METDI4752 NC_012988.1 4647865 4648038 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4647865..4648038) Methylobacterium extorquens DM4 8194139 YP_003070194.1 CDS METDI4753 NC_012988.1 4648221 4648643 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator (Ros/MucR family) 4648221..4648643 Methylobacterium extorquens DM4 8194140 YP_003070195.1 CDS METDI4754 NC_012988.1 4648801 4648998 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4648801..4648998) Methylobacterium extorquens DM4 8194141 YP_003070196.1 CDS METDI4755 NC_012988.1 4649178 4649987 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase, N-terminal 4649178..4649987 Methylobacterium extorquens DM4 8194142 YP_003070197.1 CDS METDI4756 NC_012988.1 4650047 4650292 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4650047..4650292 Methylobacterium extorquens DM4 8194143 YP_003070198.1 CDS METDI4757 NC_012988.1 4651415 4652344 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4651415..4652344 Methylobacterium extorquens DM4 8194144 YP_003070199.1 CDS METDI4758 NC_012988.1 4652878 4653117 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4652878..4653117 Methylobacterium extorquens DM4 8194145 YP_003070200.1 CDS METDI4759 NC_012988.1 4653260 4653868 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4653260..4653868 Methylobacterium extorquens DM4 8194146 YP_003070201.1 CDS METDI4760 NC_012988.1 4654119 4654697 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4654119..4654697 Methylobacterium extorquens DM4 8194147 YP_003070202.1 CDS METDI4761 NC_012988.1 4654738 4654989 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4654738..4654989) Methylobacterium extorquens DM4 8194148 YP_003070203.1 CDS METDI4762 NC_012988.1 4656176 4656997 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(4656176..4656997) Methylobacterium extorquens DM4 8196216 YP_003070204.1 CDS METDI4763 NC_012988.1 4657190 4657489 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4657190..4657489) Methylobacterium extorquens DM4 8194150 YP_003070205.1 CDS METDI4764 NC_012988.1 4657660 4658166 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, MarR family 4657660..4658166 Methylobacterium extorquens DM4 8194151 YP_003070206.1 CDS METDI4765 NC_012988.1 4658229 4658456 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4658229..4658456) Methylobacterium extorquens DM4 8194152 YP_003070207.1 CDS METDI4769 NC_012988.1 4660208 4660750 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, TetR family complement(4660208..4660750) Methylobacterium extorquens DM4 8194155 YP_003070208.1 CDS METDI4771 NC_012988.1 4660990 4664097 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative AcrB/AcrD/AcrF family protein, putative RND efflux transporter complement(4660990..4664097) Methylobacterium extorquens DM4 8194156 YP_003070209.1 CDS METDI4772 NC_012988.1 4664094 4665146 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; component of multidrug efflux system complement(4664094..4665146) Methylobacterium extorquens DM4 8194157 YP_003070210.1 CDS METDI4773 NC_012988.1 4665250 4665795 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4665250..4665795) Methylobacterium extorquens DM4 8194158 YP_003070211.1 CDS METDI4774 NC_012988.1 4666233 4667141 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(4666233..4667141) Methylobacterium extorquens DM4 8194159 YP_003070212.1 CDS METDI4775 NC_012988.1 4667191 4668117 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, aldo/keto reductase family 4667191..4668117 Methylobacterium extorquens DM4 8194160 YP_003070213.1 CDS METDI4778 NC_012988.1 4668567 4670018 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11872709; Product type pr : putative regulator; putative sensory box/GGDEF family protein 4668567..4670018 Methylobacterium extorquens DM4 8194161 YP_003070214.1 CDS METDI4779 NC_012988.1 4670373 4672169 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphodiesterase complement(4670373..4672169) Methylobacterium extorquens DM4 8194162 YP_003070215.1 CDS METDI4780 NC_012988.1 4672542 4672850 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4672542..4672850) Methylobacterium extorquens DM4 8194163 YP_003070216.1 CDS METDI4781 NC_012988.1 4673118 4674110 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative regulatory protein, LysR family 4673118..4674110 Methylobacterium extorquens DM4 8194164 YP_003070217.1 CDS METDI4782 NC_012988.1 4674642 4675706 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4674642..4675706 Methylobacterium extorquens DM4 8194165 YP_003070218.1 CDS METDI4783 NC_012988.1 4675752 4676855 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4675752..4676855 Methylobacterium extorquens DM4 8194166 YP_003070219.1 CDS METDI4784 NC_012988.1 4676968 4677591 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4676968..4677591) Methylobacterium extorquens DM4 8194167 YP_003070220.1 CDS METDI4785 NC_012988.1 4677800 4678258 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4677800..4678258) Methylobacterium extorquens DM4 8194168 YP_003070221.1 CDS METDI4786 NC_012988.1 4678335 4678595 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4678335..4678595) Methylobacterium extorquens DM4 8194169 YP_003070222.1 CDS METDI4787 NC_012988.1 4678717 4679010 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4678717..4679010) Methylobacterium extorquens DM4 8194170 YP_003070223.1 CDS METDI4790 NC_012988.1 4680047 4680226 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4680047..4680226) Methylobacterium extorquens DM4 8194173 YP_003070224.1 CDS METDI4791 NC_012988.1 4680306 4682261 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4680306..4682261) Methylobacterium extorquens DM4 8194174 YP_003070225.1 CDS METDI4792 NC_012988.1 4682441 4683943 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, PAS domain S-box 4682441..4683943 Methylobacterium extorquens DM4 8194175 YP_003070226.1 CDS METDI4793 NC_012988.1 4684083 4684265 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4684083..4684265 Methylobacterium extorquens DM4 8194176 YP_003070227.1 CDS METDI4794 NC_012988.1 4684367 4684627 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4684367..4684627 Methylobacterium extorquens DM4 8194177 YP_003070228.1 CDS METDI4795 NC_012988.1 4684676 4685650 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4684676..4685650 Methylobacterium extorquens DM4 8194178 YP_003070229.1 CDS METDI4796 NC_012988.1 4685647 4686162 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4685647..4686162 Methylobacterium extorquens DM4 8194179 YP_003070230.1 CDS METDI4797 NC_012988.1 4686134 4687018 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15188393, 16926146; hypothetical protein 4686134..4687018 Methylobacterium extorquens DM4 8194180 YP_003070231.1 CDS METDI4798 NC_012988.1 4687537 4687710 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4687537..4687710) Methylobacterium extorquens DM4 8194181 YP_003070232.1 CDS METDI4799 NC_012988.1 4687858 4688277 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4687858..4688277 Methylobacterium extorquens DM4 8194182 YP_003070233.1 CDS METDI4800 NC_012988.1 4688352 4689611 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Poly(3-hydroxybutyrate) depolymerase 4688352..4689611 Methylobacterium extorquens DM4 8194183 YP_003070234.1 CDS METDI4801 NC_012988.1 4689786 4690721 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aminohydrolase/amidase precursor complement(4689786..4690721) Methylobacterium extorquens DM4 8194184 YP_003070235.1 CDS METDI4802 NC_012988.1 4691308 4692234 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative alpha/beta hydrolase 4691308..4692234 Methylobacterium extorquens DM4 8194185 YP_003070236.1 CDS METDI4803 NC_012988.1 4692213 4693082 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-family transcriptional regulator complement(4692213..4693082) Methylobacterium extorquens DM4 8194186 YP_003070237.1 CDS METDI4804 NC_012988.1 4693179 4693397 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4693179..4693397 Methylobacterium extorquens DM4 8194187 YP_003070238.1 CDS METDI4805 NC_012988.1 4693545 4694252 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4693545..4694252 Methylobacterium extorquens DM4 8194188 YP_003070239.1 CDS METDI4806 NC_012988.1 4694699 4695502 D Evidence 5 : No homology to any previously reported sequences; PubMedId : 9782511; hypothetical protein 4694699..4695502 Methylobacterium extorquens DM4 8194189 YP_003070240.1 CDS METDI4807 NC_012988.1 4695633 4697330 D Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; methyl-accepting chemotaxis receptor/sensory transducer with PAS domain 4695633..4697330 Methylobacterium extorquens DM4 8194190 YP_003070241.1 CDS METDI4808 NC_012988.1 4697665 4699155 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Serine protease DO-like 4697665..4699155 Methylobacterium extorquens DM4 8194191 YP_003070242.1 CDS METDI4809 NC_012988.1 4699819 4700178 D inactive form; acid-resistance protein 4699819..4700178 Methylobacterium extorquens DM4 8194192 YP_003070243.1 CDS METDI4810 NC_012988.1 4700513 4700710 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2497298; hypothetical protein complement(4700513..4700710) Methylobacterium extorquens DM4 8194193 YP_003070244.1 CDS METDI4811 NC_012988.1 4700768 4702135 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative chloride channel protein complement(4700768..4702135) Methylobacterium extorquens DM4 8194194 YP_003070245.1 CDS METDI4812 NC_012988.1 4702264 4705395 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; transporter, hydrophobe/amphiphile efflux-1 (HAE1) family complement(4702264..4705395) Methylobacterium extorquens DM4 8194195 YP_003070246.1 CDS METDI4813 NC_012988.1 4705515 4706825 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative RND efflux transporter, membrane fusion protein subunit complement(4705515..4706825) Methylobacterium extorquens DM4 8194196 YP_003070247.1 CDS METDI4814 NC_012988.1 4706892 4707125 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4706892..4707125) Methylobacterium extorquens DM4 8194197 YP_003070248.1 CDS METDI4815 NC_012988.1 4707486 4707665 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4707486..4707665) Methylobacterium extorquens DM4 8194198 YP_003070249.1 CDS qxtB NC_012988.1 4707665 4708675 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11064196; Product type e : enzyme; cytochrome bd-quinol oxidase subunit II complement(4707665..4708675) Methylobacterium extorquens DM4 8194199 YP_003070250.1 CDS METDI4817 NC_012988.1 4708690 4710114 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cytochrome bd-quinol oxidase subunit I (QxtA-like) complement(4708690..4710114) Methylobacterium extorquens DM4 8195958 YP_003070251.1 CDS METDI4819 NC_012988.1 4710361 4711143 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4710361..4711143) Methylobacterium extorquens DM4 8194200 YP_003070252.1 CDS METDI4820 NC_012988.1 4711140 4711568 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, ArsR family complement(4711140..4711568) Methylobacterium extorquens DM4 8194201 YP_003070253.1 CDS METDI4821 NC_012988.1 4711565 4712464 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; beta-lactamase domain protein complement(4711565..4712464) Methylobacterium extorquens DM4 8194202 YP_003070254.1 CDS METDI4822 NC_012988.1 4712461 4713066 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peroxidase, putative peroxiredoxin complement(4712461..4713066) Methylobacterium extorquens DM4 8194203 YP_003070255.1 CDS METDI4823 NC_012988.1 4713253 4714926 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4713253..4714926 Methylobacterium extorquens DM4 8194204 YP_003070256.1 CDS METDI4824 NC_012988.1 4715175 4716302 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4715175..4716302 Methylobacterium extorquens DM4 8194205 YP_003070257.1 CDS METDI4825 NC_012988.1 4716376 4717242 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative alpha/beta hydrolase, putative epoxide hydrolase complement(4716376..4717242) Methylobacterium extorquens DM4 8194206 YP_003070258.1 CDS METDI4826 NC_012988.1 4717407 4718456 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12169610; Product type pt : putative transporter; putative ABC transporter, periplasmic protein; putative iron transporter 4717407..4718456 Methylobacterium extorquens DM4 8194207 YP_003070259.1 CDS METDI4827 NC_012988.1 4718453 4719502 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; putative ABC transporter, permease; putative iron transporter 4718453..4719502 Methylobacterium extorquens DM4 8194208 YP_003070260.1 CDS METDI4828 NC_012988.1 4719499 4720272 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATPase; putative iron transporter 4719499..4720272 Methylobacterium extorquens DM4 8194209 YP_003070261.1 CDS METDI4829 NC_012988.1 4720282 4721025 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Sulfite oxidase, oxidoreductase molybdopterin binding complement(4720282..4721025) Methylobacterium extorquens DM4 8194210 YP_003070262.1 CDS METDI4830 NC_012988.1 4721022 4721750 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4721022..4721750) Methylobacterium extorquens DM4 8194211 YP_003070263.1 CDS METDI4831 NC_012988.1 4721764 4722360 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase complement(4721764..4722360) Methylobacterium extorquens DM4 8194212 YP_003070264.1 CDS METDI4832 NC_012988.1 4722357 4723499 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyl-CoA dehydrogenase, putative exported protein complement(4722357..4723499) Methylobacterium extorquens DM4 8194213 YP_003070265.1 CDS METDI4833 NC_012988.1 4723774 4724061 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4723774..4724061 Methylobacterium extorquens DM4 8194214 YP_003070266.1 CDS METDI4834 NC_012988.1 4724067 4724312 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4724067..4724312 Methylobacterium extorquens DM4 8194215 YP_003070267.1 CDS METDI4835 NC_012988.1 4724315 4724533 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4724315..4724533 Methylobacterium extorquens DM4 8194216 YP_003070268.1 CDS METDI4836 NC_012988.1 4724621 4725655 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, aldo/keto reductase family complement(4724621..4725655) Methylobacterium extorquens DM4 8194217 YP_003070269.1 CDS METDI4837 NC_012988.1 4725971 4726198 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4725971..4726198 Methylobacterium extorquens DM4 8194218 YP_003070270.1 CDS METDI4838 NC_012988.1 4726204 4726803 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Isochorismatase hydrolase complement(4726204..4726803) Methylobacterium extorquens DM4 8194219 YP_003070271.1 CDS ragD NC_012988.1 4727077 4728351 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9140968; Product type t : transporter; Efflux transporter, RND family, membrane fusion protein subunit complement(4727077..4728351) Methylobacterium extorquens DM4 8194220 YP_003070272.1 CDS ragC NC_012988.1 4728386 4731616 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10675036; Product type t : transporter; multidrug efflux pump complement(4728386..4731616) Methylobacterium extorquens DM4 8195963 YP_003070273.1 CDS METDI4841 NC_012988.1 4731930 4733306 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4731930..4733306) Methylobacterium extorquens DM4 8195962 YP_003070274.1 CDS METDI4842 NC_012988.1 4733303 4733998 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4733303..4733998) Methylobacterium extorquens DM4 8194221 YP_003070275.1 CDS METDI4843 NC_012988.1 4734030 4734959 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase precursor, putative aldo/keto reductase precursor (tat pathway signal) complement(4734030..4734959) Methylobacterium extorquens DM4 8194222 YP_003070276.1 CDS yhhF NC_012988.1 4735032 4735586 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase with SAM-dependent methyltransferase domain complement(4735032..4735586) Methylobacterium extorquens DM4 8194223 YP_003070277.1 CDS METDI4845 NC_012988.1 4735599 4737608 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4735599..4737608) Methylobacterium extorquens DM4 8196368 YP_003070278.1 CDS METDI4846 NC_012988.1 4737699 4737875 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4737699..4737875) Methylobacterium extorquens DM4 8194224 YP_003070279.1 CDS arsH NC_012988.1 4738043 4738810 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346; Product type e : enzyme; NADPH-dependent FMN reductase complement(4738043..4738810) Methylobacterium extorquens DM4 8194225 YP_003070280.1 CDS arsR NC_012988.1 4738861 4739220 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346, 12829264, 9537360; Product type r : regulator; transcriptional regulator, ArsR family 4738861..4739220 Methylobacterium extorquens DM4 8195103 YP_003070281.1 CDS arsC NC_012988.1 4739213 4739650 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16905151, 17432936; Product type e : enzyme; arsenate reductase (glutaredoxin family) 4739213..4739650 Methylobacterium extorquens DM4 8195106 YP_003070282.1 CDS METDI4850 NC_012988.1 4739660 4740736 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative arsenite efflux pump ACR3 precursor 4739660..4740736 Methylobacterium extorquens DM4 8195100 YP_003070283.1 CDS METDI4851 NC_012988.1 4740937 4743039 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL) with PAS/PAC sensor complement(4740937..4743039) Methylobacterium extorquens DM4 8194226 YP_003070284.1 CDS METDI4852 NC_012988.1 4743343 4744260 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1512562; Product type pe : putative enzyme; putative alpha/beta hydrolase, putative haloacetate dehalogenase 4743343..4744260 Methylobacterium extorquens DM4 8194227 YP_003070285.1 CDS METDI4853 NC_012988.1 4744265 4744966 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative short-chain dehydrogenase/reductase SDR complement(4744265..4744966) Methylobacterium extorquens DM4 8194228 YP_003070286.1 CDS tadA NC_012988.1 4745058 4745501 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12110595; Product type e : enzyme; tRNA-specific adenosine deaminase complement(4745058..4745501) Methylobacterium extorquens DM4 8194229 YP_003070287.1 CDS purD NC_012988.1 4745515 4746822 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2687276, 9843369; Product type e : enzyme; phosphoribosylglycinamide synthetase (GAR synthetase) complement(4745515..4746822) Methylobacterium extorquens DM4 8196177 YP_003070288.1 CDS METDI4856 NC_012988.1 4746906 4747643 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4746906..4747643 Methylobacterium extorquens DM4 8195932 YP_003070289.1 CDS METDI4857 NC_012988.1 4747730 4747945 D Evidence 6 : Doubtful CDS; hypothetical protein 4747730..4747945 Methylobacterium extorquens DM4 8194230 YP_003070290.1 CDS xseA NC_012988.1 4748169 4749737 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3021756, 6284744; Product type pe : putative enzyme; putative exonuclease VII, large subunit OB-fold nucleic acid binding domain 4748169..4749737 Methylobacterium extorquens DM4 8194231 YP_003070291.1 CDS METDI4859 NC_012988.1 4749794 4750171 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4749794..4750171) Methylobacterium extorquens DM4 8196343 YP_003070292.1 CDS METDI4860 NC_012988.1 4750386 4750613 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4750386..4750613 Methylobacterium extorquens DM4 8194232 YP_003070293.1 CDS prs NC_012988.1 4750781 4751725 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3009477; Product type e : enzyme; phosphoribosylpyrophosphate synthetase 4750781..4751725 Methylobacterium extorquens DM4 8194233 YP_003070294.1 CDS METDI4862 NC_012988.1 4751847 4752311 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8431948; Product type pe : putative enzyme; putative GreA/GreB family transcription elongation factor complement(4751847..4752311) Methylobacterium extorquens DM4 8195907 YP_003070295.1 CDS METDI4863 NC_012988.1 4752332 4753330 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15388933, 8020473, 8049268; Product type pe : putative enzyme; putative Zn-dependent oxidoreductase, NAD(P)-binding and GroES-like domains complement(4752332..4753330) Methylobacterium extorquens DM4 8194234 YP_003070296.1 CDS METDI4864 NC_012988.1 4753436 4754035 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4753436..4754035) Methylobacterium extorquens DM4 8194235 YP_003070297.1 CDS fdxA NC_012988.1 4754514 4754852 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2388848; Product type e : enzyme; ferredoxin II 4754514..4754852 Methylobacterium extorquens DM4 8194236 YP_003070298.1 CDS METDI4866 NC_012988.1 4755288 4755962 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11535780; Product type r : regulator; transcriptional regulator, CarD family 4755288..4755962 Methylobacterium extorquens DM4 8195371 YP_003070299.1 CDS rpoH2 NC_012988.1 4756245 4757117 D binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 4756245..4757117 Methylobacterium extorquens DM4 8194237 YP_003070300.1 CDS gid NC_012988.1 4759456 4760928 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(4759456..4760928) Methylobacterium extorquens DM4 8194240 YP_003070301.1 CDS METDI4872 NC_012988.1 4761174 4762796 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4761174..4762796 Methylobacterium extorquens DM4 8195483 YP_003070302.1 CDS METDI4873 NC_012988.1 4762835 4763809 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative serine protease, htrA-like complement(4762835..4763809) Methylobacterium extorquens DM4 8194241 YP_003070303.1 CDS METDI4874 NC_012988.1 4764250 4764804 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor 4764250..4764804 Methylobacterium extorquens DM4 8194242 YP_003070304.1 CDS METDI4875 NC_012988.1 4764801 4765580 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4764801..4765580 Methylobacterium extorquens DM4 8194243 YP_003070305.1 CDS METDI4876 NC_012988.1 4765745 4766683 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10433972; Product type pf : putative factor; putative CoxB-related complement(4765745..4766683) Methylobacterium extorquens DM4 8194244 YP_003070306.1 CDS uvrA NC_012988.1 4767239 4770304 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1826851; Product type e : enzyme; DNA excision repair enzyme subunit, with UvrBC complement(4767239..4770304) Methylobacterium extorquens DM4 8194245 YP_003070307.1 CDS METDI4878 NC_012988.1 4770725 4771783 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4770725..4771783 Methylobacterium extorquens DM4 8196329 YP_003070308.1 CDS METDI4879 NC_012988.1 4771946 4773985 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4771946..4773985 Methylobacterium extorquens DM4 8194246 YP_003070309.1 CDS METDI4880 NC_012988.1 4774104 4775309 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative RND efflux transporter, membrane fusion protein subunit complement(4774104..4775309) Methylobacterium extorquens DM4 8194247 YP_003070310.1 CDS METDI4881 NC_012988.1 4775464 4778628 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Multidrug resistance protein mexB (Multidrug-efflux transporter mexB) 4775464..4778628 Methylobacterium extorquens DM4 8194248 YP_003070311.1 CDS METDI4882 NC_012988.1 4778639 4779040 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Response regulator receiver complement(4778639..4779040) Methylobacterium extorquens DM4 8194249 YP_003070312.1 CDS METDI4883 NC_012988.1 4779145 4781925 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase of the HWE family complement(4779145..4781925) Methylobacterium extorquens DM4 8194250 YP_003070313.1 CDS METDI4885 NC_012988.1 4782151 4782912 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, Crp/Fnr family complement(4782151..4782912) Methylobacterium extorquens DM4 8194251 YP_003070314.1 CDS METDI4886 NC_012988.1 4783167 4784018 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Glycoside hydrolase, family 25 complement(4783167..4784018) Methylobacterium extorquens DM4 8194252 YP_003070315.1 CDS METDI4887 NC_012988.1 4784216 4784668 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4784216..4784668 Methylobacterium extorquens DM4 8194253 YP_003070316.1 CDS ubiH NC_012988.1 4784723 4785958 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10858449; Product type e : enzyme; 2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase) complement(4784723..4785958) Methylobacterium extorquens DM4 8194254 YP_003070317.1 CDS METDI4889 NC_012988.1 4786371 4786574 D Evidence 6 : Doubtful CDS; hypothetical protein 4786371..4786574 Methylobacterium extorquens DM4 8196296 YP_003070318.1 CDS METDI4890 NC_012988.1 4786571 4786798 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4786571..4786798 Methylobacterium extorquens DM4 8194255 YP_003070319.1 CDS qor NC_012988.1 4786987 4787958 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7602590, 94089392; Product type e : enzyme; quinone oxidoreductase, NADPH-dependent 4786987..4787958 Methylobacterium extorquens DM4 8194256 YP_003070320.1 CDS pncA NC_012988.1 4788143 4788769 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2670682, 72060410, 8726014; Product type e : enzyme; nicotinamidase 4788143..4788769 Methylobacterium extorquens DM4 8195954 YP_003070321.1 CDS METDI4893 NC_012988.1 4788939 4789796 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12670965; Product type pe : putative enzyme; putative branched-chain amino acid aminotransferase complement(4788939..4789796) Methylobacterium extorquens DM4 8195869 YP_003070322.1 CDS pabA NC_012988.1 4789783 4790412 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2071583, 7592344, 8096767; Product type e : enzyme; aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex complement(4789783..4790412) Methylobacterium extorquens DM4 8194257 YP_003070323.1 CDS METDI4895 NC_012988.1 4790409 4791809 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2251281, 3057324; Product type e : enzyme; putative para-aminobenzoate synthase component complement(4790409..4791809) Methylobacterium extorquens DM4 8195822 YP_003070324.1 CDS dinJ NC_012988.1 4792102 4792365 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; RelB/dinJ family addiction module antitoxin 4792102..4792365 Methylobacterium extorquens DM4 8194258 YP_003070325.1 CDS METDI4897 NC_012988.1 4792403 4792633 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; RelE/StbE family addiction module toxin 4792403..4792633 Methylobacterium extorquens DM4 8195296 YP_003070326.1 CDS rimO NC_012988.1 4792750 4794096 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 4792750..4794096 Methylobacterium extorquens DM4 8194259 YP_003070327.1 CDS METDI4899 NC_012988.1 4794193 4794378 D Evidence 6 : Doubtful CDS; hypothetical protein 4794193..4794378 Methylobacterium extorquens DM4 8196372 YP_003070328.1 CDS METDI4900 NC_012988.1 4794385 4794807 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4794385..4794807 Methylobacterium extorquens DM4 8194260 YP_003070329.1 CDS METDI4901 NC_012988.1 4794896 4795087 D Evidence 6 : Doubtful CDS; hypothetical protein 4794896..4795087 Methylobacterium extorquens DM4 8194261 YP_003070330.1 CDS mazG NC_012988.1 4795172 4796002 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12218018; Product type e : enzyme; nucleoside triphosphate pyrophosphohydrolase MazG complement(4795172..4796002) Methylobacterium extorquens DM4 8194262 YP_003070331.1 CDS METDI4903 NC_012988.1 4796757 4797854 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Plasmid replication protein RepA 4796757..4797854 Methylobacterium extorquens DM4 8195664 YP_003070332.1 CDS METDI4904 NC_012988.1 4798332 4798886 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4798332..4798886 Methylobacterium extorquens DM4 8194263 YP_003070333.1 CDS METDI4905 NC_012988.1 4799017 4800324 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative patatin-like phospholipase complement(4799017..4800324) Methylobacterium extorquens DM4 8194264 YP_003070334.1 CDS METDI4906 NC_012988.1 4800843 4801892 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16926146; Product type pe : putative enzyme; putative carbon-carbon lyase, HpcH/HpaI aldolase/citrate lyase family 4800843..4801892 Methylobacterium extorquens DM4 8194265 YP_003070335.1 CDS METDI4907 NC_012988.1 4801916 4802290 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12700277; Product type f : factor; putative DNA-binding protein, hemimethylated (yccV-like) 4801916..4802290 Methylobacterium extorquens DM4 8194266 YP_003070336.1 CDS METDI4908 NC_012988.1 4802471 4803697 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase precursor (GGDEF motif); putative membrane protein 4802471..4803697 Methylobacterium extorquens DM4 8194267 YP_003070337.1 CDS METDI4909 NC_012988.1 4803849 4804031 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4803849..4804031) Methylobacterium extorquens DM4 8194268 YP_003070338.1 CDS METDI4910 NC_012988.1 4804314 4805522 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative efflux transporter, membrane fusion protein subunit precursor; putative HlyD family secretion protein precursor 4804314..4805522 Methylobacterium extorquens DM4 8194269 YP_003070339.1 CDS METDI4911 NC_012988.1 4805533 4808673 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; efflux transporter, AcrB/AcrD/AcrF family protein 4805533..4808673 Methylobacterium extorquens DM4 8194270 YP_003070340.1 CDS METDI4912 NC_012988.1 4808703 4808969 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4808703..4808969) Methylobacterium extorquens DM4 8194271 YP_003070341.1 CDS METDI4913 NC_012988.1 4809089 4810246 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal-dependent phosphohydrolase (HD domain) 4809089..4810246 Methylobacterium extorquens DM4 8194272 YP_003070342.1 CDS METDI4914 NC_012988.1 4810300 4811337 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; agmatinase (ureohydrolase) complement(4810300..4811337) Methylobacterium extorquens DM4 8194273 YP_003070343.1 CDS METDI4915 NC_012988.1 4811690 4812694 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4811690..4812694 Methylobacterium extorquens DM4 8194274 YP_003070344.1 CDS METDI4916 NC_012988.1 4812866 4813180 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4812866..4813180) Methylobacterium extorquens DM4 8194275 YP_003070345.1 CDS coaBC NC_012988.1 4813380 4814669 R (DNA/pantothenate metabolism flavoprotein) [Phosphopantothenoylcysteine decarboxylase (PPCDC) (CoaC); Phosphopantothenate-cysteine ligase (Phosphopantothenoylcysteine synthase) (PPC synthetase) (PPCS) (CoaB)]; Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Coenzyme A biosynthesis bifunctional protein coaBC complement(4813380..4814669) Methylobacterium extorquens DM4 8194276 YP_003070346.1 CDS METDI4918 NC_012988.1 4814910 4816010 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative restriction endonuclease or methylase 4814910..4816010 Methylobacterium extorquens DM4 8195178 YP_003070347.1 CDS METDI4919 NC_012988.1 4816021 4816248 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4816021..4816248) Methylobacterium extorquens DM4 8194277 YP_003070348.1 CDS ubiB NC_012988.1 4816291 4817856 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10960098, 11583838; Product type e : enzyme; ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase complement(4816291..4817856) Methylobacterium extorquens DM4 8194278 YP_003070349.1 CDS ubiE NC_012988.1 4818080 4818859 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10960098, 1444716, 195601, 365223, 4323297, 9045837; Product type e : enzyme; Ubiquinone/menaquinone biosynthesis methyltransferase ubiE complement(4818080..4818859) Methylobacterium extorquens DM4 8196294 YP_003070350.1 CDS dmrA NC_012988.1 4818990 4819397 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; Dihydromethanopterin reductase complement(4818990..4819397) Methylobacterium extorquens DM4 8196295 YP_003070351.1 CDS METDI4923 NC_012988.1 4819470 4820213 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(4819470..4820213) Methylobacterium extorquens DM4 8195300 YP_003070352.1 CDS purF NC_012988.1 4820219 4821694 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(4820219..4821694) Methylobacterium extorquens DM4 8194279 YP_003070353.1 CDS METDI4925 NC_012988.1 4822093 4822686 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2542219, 2991286; Product type m : membrane component; Colicin V-related production protein (membrane protein dedE-related) (putative Pur regulon protein) complement(4822093..4822686) Methylobacterium extorquens DM4 8195934 YP_003070354.1 CDS METDI4926 NC_012988.1 4823074 4824192 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallo-hydrolase/oxidoreductase precursor, putative exonuclease precursor (tat pathway signal) 4823074..4824192 Methylobacterium extorquens DM4 8194280 YP_003070355.1 CDS METDI4927 NC_012988.1 4824185 4824802 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4824185..4824802 Methylobacterium extorquens DM4 8194281 YP_003070356.1 CDS radA NC_012988.1 4824830 4826260 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(4824830..4826260) Methylobacterium extorquens DM4 8194282 YP_003070357.1 CDS METDI4929 NC_012988.1 4826440 4827468 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative alanine racemase (alr-like) complement(4826440..4827468) Methylobacterium extorquens DM4 8195959 YP_003070358.1 CDS dnaB NC_012988.1 4827626 4829113 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; replicative DNA helicase (dnaB) complement(4827626..4829113) Methylobacterium extorquens DM4 8194283 YP_003070359.1 CDS rplI NC_012988.1 4829434 4830006 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(4829434..4830006) Methylobacterium extorquens DM4 8195303 YP_003070360.1 CDS METDI4932 NC_012988.1 4830044 4831102 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4830044..4831102) Methylobacterium extorquens DM4 8196020 YP_003070361.1 CDS rpsR NC_012988.1 4831238 4831492 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(4831238..4831492) Methylobacterium extorquens DM4 8194284 YP_003070362.1 CDS rpsF NC_012988.1 4831495 4831950 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(4831495..4831950) Methylobacterium extorquens DM4 8196069 YP_003070363.1 CDS METDI4935 NC_012988.1 4832151 4832699 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2549372; Product type e : enzyme; Gentamicin 3'-N-acetyltransferase complement(4832151..4832699) Methylobacterium extorquens DM4 8196057 YP_003070364.1 CDS METDI4936 NC_012988.1 4832709 4833083 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4832709..4833083) Methylobacterium extorquens DM4 8194285 YP_003070365.1 CDS METDI4937 NC_012988.1 4833155 4833484 R Evidence 5 : No homology to any previously reported sequences; PubMedId : 12957906; hypothetical protein complement(4833155..4833484) Methylobacterium extorquens DM4 8194286 YP_003070366.1 CDS METDI4938 NC_012988.1 4833894 4834274 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4833894..4834274) Methylobacterium extorquens DM4 8194287 YP_003070367.1 CDS cspA NC_012988.1 4834520 4834729 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10515936, 10618253, 10696873; Product type f : factor; cold shock protein A complement(4834520..4834729) Methylobacterium extorquens DM4 8194288 YP_003070368.1 CDS METDI4940 NC_012988.1 4835322 4835582 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4835322..4835582) Methylobacterium extorquens DM4 8195224 YP_003070369.1 CDS def NC_012988.1 4836034 4836564 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 4836034..4836564 Methylobacterium extorquens DM4 8194289 YP_003070370.1 CDS METDI4942 NC_012988.1 4836690 4837133 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4836690..4837133 Methylobacterium extorquens DM4 8195285 YP_003070371.1 CDS METDI4943 NC_012988.1 4837155 4839326 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; TonB-dependent receptor/siderophore receptor protein complement(4837155..4839326) Methylobacterium extorquens DM4 8194290 YP_003070372.1 CDS METDI4944 NC_012988.1 4839615 4840460 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4839615..4840460 Methylobacterium extorquens DM4 8194291 YP_003070373.1 CDS METDI4945 NC_012988.1 4840477 4840986 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4840477..4840986) Methylobacterium extorquens DM4 8194292 YP_003070374.1 CDS METDI4946 NC_012988.1 4841324 4841815 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; GCN5-related N-acetyltransferase 4841324..4841815 Methylobacterium extorquens DM4 8194293 YP_003070375.1 CDS METDI4947 NC_012988.1 4841896 4843287 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; H+/gluconate symporter family protein 4841896..4843287 Methylobacterium extorquens DM4 8194294 YP_003070376.1 CDS dctA NC_012988.1 4843436 4844752 D involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4843436..4844752 Methylobacterium extorquens DM4 8194295 YP_003070377.1 CDS METDI4949 NC_012988.1 4844857 4845918 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 4844857..4845918 Methylobacterium extorquens DM4 8195281 YP_003070378.1 CDS aspA NC_012988.1 4845945 4847660 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Aspartate ammonia-lyase (Aspartase) complement(4845945..4847660) Methylobacterium extorquens DM4 8194296 YP_003070379.1 CDS METDI4951 NC_012988.1 4847840 4849381 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4847840..4849381) Methylobacterium extorquens DM4 8195110 YP_003070380.1 CDS METDI4952 NC_012988.1 4850072 4851754 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1370281; Product type pt : putative transporter; putative porin 4850072..4851754 Methylobacterium extorquens DM4 8194297 YP_003070381.1 CDS gltI NC_012988.1 4851956 4852867 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10493123, 1091635, 1091636, 10972807, 8740179; Product type t : transporter; glutamate and aspartate transporter subunit ; periplasmic-binding component of ABC superfamily 4851956..4852867 Methylobacterium extorquens DM4 8194298 YP_003070382.1 CDS gltJ NC_012988.1 4852902 4853624 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate transporter subunit ; membrane component of ABC superfamily 4852902..4853624 Methylobacterium extorquens DM4 8195514 YP_003070383.1 CDS glnP NC_012988.1 4853624 4854316 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; glutamate/aspartate transport protein, ABC superfamily, permease component 4853624..4854316 Methylobacterium extorquens DM4 8195515 YP_003070384.1 CDS gltL NC_012988.1 4854343 4855119 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate transporter subunit ; ATP-binding component of ABC superfamily 4854343..4855119 Methylobacterium extorquens DM4 8195506 YP_003070385.1 CDS METDI4957 NC_012988.1 4855209 4856162 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4855209..4856162) Methylobacterium extorquens DM4 8195516 YP_003070386.1 CDS arsB NC_012988.1 4856198 4857466 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; arsenite/antimonite transporter complement(4856198..4857466) Methylobacterium extorquens DM4 8194299 YP_003070387.1 CDS METDI4959 NC_012988.1 4857843 4858118 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4857843..4858118 Methylobacterium extorquens DM4 8195096 YP_003070388.1 CDS METDI4960 NC_012988.1 4858450 4859067 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15188393, 16926146; hypothetical protein complement(4858450..4859067) Methylobacterium extorquens DM4 8194300 YP_003070389.1 CDS METDI4961 NC_012988.1 4859328 4860107 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4859328..4860107 Methylobacterium extorquens DM4 8194301 YP_003070390.1 CDS METDI4962 NC_012988.1 4860109 4861089 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4860109..4861089 Methylobacterium extorquens DM4 8194302 YP_003070391.1 CDS METDI4963 NC_012988.1 4861101 4861994 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4861101..4861994 Methylobacterium extorquens DM4 8194303 YP_003070392.1 CDS METDI4964 NC_012988.1 4862241 4866323 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative non-ribosomal peptide synthetase 4862241..4866323 Methylobacterium extorquens DM4 8194304 YP_003070393.1 CDS METDI4965 NC_012988.1 4866402 4866614 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4866402..4866614 Methylobacterium extorquens DM4 8194305 YP_003070394.1 CDS METDI4966 NC_012988.1 4866614 4866892 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1748867; hypothetical protein 4866614..4866892 Methylobacterium extorquens DM4 8194306 YP_003070395.1 CDS METDI4967 NC_012988.1 4866914 4867570 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4866914..4867570) Methylobacterium extorquens DM4 8194307 YP_003070396.1 CDS iscS NC_012988.1 4867831 4869003 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent 4867831..4869003 Methylobacterium extorquens DM4 8194308 YP_003070397.1 CDS sufB NC_012988.1 4869097 4870566 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; FeS assembly protein SufB 4869097..4870566 Methylobacterium extorquens DM4 8195605 YP_003070398.1 CDS sufC NC_012988.1 4870855 4871607 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10322040, 12089140; Product type t : transporter; FeS assembly ATPase SufC 4870855..4871607 Methylobacterium extorquens DM4 8196170 YP_003070399.1 CDS sufD NC_012988.1 4871607 4872929 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; FeS assembly protein SufD 4871607..4872929 Methylobacterium extorquens DM4 8196171 YP_003070400.1 CDS sufS NC_012988.1 4873184 4874440 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10684605, 12876288; Product type e : enzyme; cysteine desulfurase 4873184..4874440 Methylobacterium extorquens DM4 8196172 YP_003070401.1 CDS METDI4973 NC_012988.1 4874491 4874874 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4874491..4874874 Methylobacterium extorquens DM4 8196173 YP_003070402.1 CDS METDI4974 NC_012988.1 4874924 4875505 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4874924..4875505) Methylobacterium extorquens DM4 8194309 YP_003070403.1 CDS METDI4975 NC_012988.1 4875687 4876067 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; iron-sulfur cluster assembly accessory protein 4875687..4876067 Methylobacterium extorquens DM4 8194310 YP_003070404.1 CDS METDI4976 NC_012988.1 4876164 4877231 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (2 GGDEF motifs) complement(4876164..4877231) Methylobacterium extorquens DM4 8194311 YP_003070405.1 CDS rhlE NC_012988.1 4877468 4879021 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; RNA helicase complement(4877468..4879021) Methylobacterium extorquens DM4 8194312 YP_003070406.1 CDS METDI4978 NC_012988.1 4879312 4879551 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4879312..4879551) Methylobacterium extorquens DM4 8195990 YP_003070407.1 CDS METDI4979 NC_012988.1 4879906 4880772 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8589412, 8751924; Product type pm : putative membrane component; putative outer-membrane immunogenic protein precursor 4879906..4880772 Methylobacterium extorquens DM4 8194313 YP_003070408.1 CDS METDI4980 NC_012988.1 4881090 4881440 D Evidence 6 : Doubtful CDS; hypothetical protein 4881090..4881440 Methylobacterium extorquens DM4 8194314 YP_003070409.1 CDS METDI4981 NC_012988.1 4881437 4881841 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4881437..4881841 Methylobacterium extorquens DM4 8194315 YP_003070410.1 CDS METDI4982 NC_012988.1 4882001 4882273 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4882001..4882273 Methylobacterium extorquens DM4 8194316 YP_003070411.1 CDS METDI4983 NC_012988.1 4882336 4882737 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4882336..4882737 Methylobacterium extorquens DM4 8194317 YP_003070412.1 CDS METDI4984 NC_012988.1 4882936 4883226 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4882936..4883226 Methylobacterium extorquens DM4 8194318 YP_003070413.1 CDS METDI4985 NC_012988.1 4883241 4883912 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative haloacid dehalogenase family hydrolase 4883241..4883912 Methylobacterium extorquens DM4 8194319 YP_003070414.1 CDS METDI4986 NC_012988.1 4884060 4884257 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4884060..4884257 Methylobacterium extorquens DM4 8194320 YP_003070415.1 CDS METDI4987 NC_012988.1 4884380 4885072 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, ATPase complement(4884380..4885072) Methylobacterium extorquens DM4 8194321 YP_003070416.1 CDS METDI4988 NC_012988.1 4885167 4885949 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyl-CoA thioesterase precursor (tesA-like) 4885167..4885949 Methylobacterium extorquens DM4 8194322 YP_003070417.1 CDS METDI4989 NC_012988.1 4885956 4886522 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8940112; Product type pe : putative enzyme; putative 2'-5' RNA ligase 4885956..4886522 Methylobacterium extorquens DM4 8194323 YP_003070418.1 CDS METDI4990 NC_012988.1 4886877 4887179 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative SecE subunit of protein translocation complex preprotein, (across inner membrane), (General Secretory Pathway) 4886877..4887179 Methylobacterium extorquens DM4 8196270 YP_003070419.1 CDS nusG NC_012988.1 4887223 4887756 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1532577, 2137819, 7505669, 8422985, 92112854, 92191277, 9571053, 10383769; Product type f : factor; transcription termination factor 4887223..4887756 Methylobacterium extorquens DM4 8194325 YP_003070420.1 CDS rplK NC_012988.1 4887985 4888434 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4887985..4888434 Methylobacterium extorquens DM4 8195803 YP_003070421.1 CDS rplA NC_012988.1 4888446 4889144 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4888446..4889144 Methylobacterium extorquens DM4 8196019 YP_003070422.1 CDS METDI4994 NC_012988.1 4889281 4890519 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1732208; Product type pc : putative carrier; putative cytochrome P450 reductase complement(4889281..4890519) Methylobacterium extorquens DM4 8196012 YP_003070423.1 CDS METDI4995 NC_012988.1 4890524 4891786 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1569021, 7836301, 8344526; Product type pe : putative enzyme; putative NAD(FAD)-dependent oxidoreductase complement(4890524..4891786) Methylobacterium extorquens DM4 8194326 YP_003070424.1 CDS METDI4996 NC_012988.1 4891783 4892004 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7126685, 7803404, 9533888; Product type pf : putative factor; putative Ferredoxin; putative 4Fe-4S ferredoxins domain complement(4891783..4892004) Methylobacterium extorquens DM4 8194327 YP_003070425.1 CDS METDI4997 NC_012988.1 4892159 4893241 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4892159..4893241) Methylobacterium extorquens DM4 8194328 YP_003070426.1 CDS METDI4998 NC_012988.1 4893238 4894122 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15294902, 7512872, 7517390; Product type pe : putative enzyme; putative glycosyl transferase complement(4893238..4894122) Methylobacterium extorquens DM4 8194329 YP_003070427.1 CDS aspS NC_012988.1 4894271 4896085 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aspartate tRNA synthetase complement(4894271..4896085) Methylobacterium extorquens DM4 8194330 YP_003070428.1 CDS bioB NC_012988.1 4896187 4897194 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11834738, 12475249, 14704425, 14967041; Product type e : enzyme; biotin synthetase complement(4896187..4897194) Methylobacterium extorquens DM4 8195111 YP_003070429.1 CDS METDI5001 NC_012988.1 4897388 4897774 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4897388..4897774 Methylobacterium extorquens DM4 8195142 YP_003070430.1 CDS hpaG NC_012988.1 4897860 4898744 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2-hydroxyhepta-2,4-diene-1, 7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase complement(4897860..4898744) Methylobacterium extorquens DM4 8194331 YP_003070431.1 CDS METDI5003 NC_012988.1 4898998 4900323 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative long-chain fatty acid outer membrane transporter (fadL) 4898998..4900323 Methylobacterium extorquens DM4 8195572 YP_003070432.1 CDS METDI5004 NC_012988.1 4900481 4901281 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4900481..4901281) Methylobacterium extorquens DM4 8194332 YP_003070433.1 CDS METDI5005 NC_012988.1 4901682 4904135 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL) with PAS sensor 4901682..4904135 Methylobacterium extorquens DM4 8194333 YP_003070434.1 CDS METDI5006 NC_012988.1 4904236 4905879 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4904236..4905879) Methylobacterium extorquens DM4 8194334 YP_003070435.1 CDS METDI5007 NC_012988.1 4906653 4908161 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4906653..4908161 Methylobacterium extorquens DM4 8194335 YP_003070436.1 CDS METDI5008 NC_012988.1 4908205 4908354 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4908205..4908354) Methylobacterium extorquens DM4 8194336 YP_003070437.1 CDS rplJ NC_012988.1 4909029 4909547 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4909029..4909547 Methylobacterium extorquens DM4 8194337 YP_003070438.1 CDS rplL NC_012988.1 4909605 4909982 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4909605..4909982 Methylobacterium extorquens DM4 8196018 YP_003070439.1 CDS rpoB NC_012988.1 4910244 4914374 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4910244..4914374 Methylobacterium extorquens DM4 8196021 YP_003070440.1 CDS rpoC NC_012988.1 4914553 4918770 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4914553..4918770 Methylobacterium extorquens DM4 8196045 YP_003070441.1 CDS potF NC_012988.1 4919004 4920104 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8416922, 9298646, 93106992, 9651355; Product type t : transporter; putrescine transporter subunit: periplasmic-binding component of ABC superfamily complement(4919004..4920104) Methylobacterium extorquens DM4 8196046 YP_003070442.1 CDS METDI5014 NC_012988.1 4920101 4920460 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4920101..4920460) Methylobacterium extorquens DM4 8195875 YP_003070443.1 CDS METDI5015 NC_012988.1 4920711 4920977 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4920711..4920977 Methylobacterium extorquens DM4 8190536 YP_003070444.1 CDS METDI5016 NC_012988.1 4921643 4922125 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, HxlR family 4921643..4922125 Methylobacterium extorquens DM4 8194339 YP_003070445.1 CDS METDI5017 NC_012988.1 4922191 4922424 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4922191..4922424) Methylobacterium extorquens DM4 8194340 YP_003070446.1 CDS METDI5018 NC_012988.1 4922506 4923147 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(4922506..4923147) Methylobacterium extorquens DM4 8194341 YP_003070447.1 CDS METDI5019 NC_012988.1 4923240 4925480 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent iron outer membrane transporter (fiu) complement(4923240..4925480) Methylobacterium extorquens DM4 8194342 YP_003070448.1 CDS pnp NC_012988.1 4925728 4927974 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; polynucleotide phosphorylase/polyadenylase complement(4925728..4927974) Methylobacterium extorquens DM4 8194343 YP_003070449.1 CDS rpsO NC_012988.1 4928244 4928513 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(4928244..4928513) Methylobacterium extorquens DM4 8195870 YP_003070450.1 CDS METDI5022 NC_012988.1 4928813 4930279 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Amino acid transporter 4928813..4930279 Methylobacterium extorquens DM4 8196066 YP_003070451.1 CDS METDI5023 NC_012988.1 4930342 4930455 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4930342..4930455) Methylobacterium extorquens DM4 8194344 YP_003070452.1 CDS xthA NC_012988.1 4930525 4931334 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3049539; Product type e : enzyme; Exodeoxyribonuclease III (Exonuclease III) (EXO III) (AP endonuclease VI) complement(4930525..4931334) Methylobacterium extorquens DM4 8194345 YP_003070453.1 CDS METDI5025 NC_012988.1 4931403 4931849 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative activator of photopigment and puc with BLUF domain complement(4931403..4931849) Methylobacterium extorquens DM4 8196346 YP_003070454.1 CDS METDI5026 NC_012988.1 4931866 4933569 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11843302; Product type pe : putative enzyme; putative diguanylate cyclase (GGDEF) /phosphodiesterase (EAL) precursor with PAS sensor complement(4931866..4933569) Methylobacterium extorquens DM4 8194346 YP_003070455.1 CDS METDI5027 NC_012988.1 4933788 4934735 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4933788..4934735) Methylobacterium extorquens DM4 8194347 YP_003070456.1 CDS ftsK NC_012988.1 4934915 4938208 R Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; Cell division protein complement(4934915..4938208) Methylobacterium extorquens DM4 8194348 YP_003070457.1 CDS nadE NC_012988.1 4938646 4940718 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 4938646..4940718 Methylobacterium extorquens DM4 8195454 YP_003070458.1 CDS METDI5030 NC_012988.1 4940742 4941206 R LovR from Caulobacter crescentus is a response regulator part of a two-component signaling system that regulates photosensitive bacterial cell-surface and cell-cell attachment; response regulator complement(4940742..4941206) Methylobacterium extorquens DM4 8195769 YP_003070459.1 CDS METDI5031 NC_012988.1 4941340 4942395 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase, domains HK, ATPase and sensory PAS complement(4941340..4942395) Methylobacterium extorquens DM4 8194349 YP_003070460.1 CDS METDI5032 NC_012988.1 4942832 4944280 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transport transmembrane protein, AmpG 4942832..4944280 Methylobacterium extorquens DM4 8194350 YP_003070461.1 CDS METDI5033 NC_012988.1 4944277 4945203 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4944277..4945203 Methylobacterium extorquens DM4 8194351 YP_003070462.1 CDS METDI5034 NC_012988.1 4945389 4946573 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4945389..4946573) Methylobacterium extorquens DM4 8194352 YP_003070463.1 CDS METDI5035 NC_012988.1 4946654 4947259 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4946654..4947259 Methylobacterium extorquens DM4 8194353 YP_003070464.1 CDS METDI5036 NC_012988.1 4947650 4948360 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4947650..4948360 Methylobacterium extorquens DM4 8194354 YP_003070465.1 CDS engA NC_012988.1 4948447 4949787 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 4948447..4949787 Methylobacterium extorquens DM4 8194355 YP_003070466.1 CDS METDI5038 NC_012988.1 4949956 4950858 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4949956..4950858 Methylobacterium extorquens DM4 8195329 YP_003070467.1 CDS METDI5039 NC_012988.1 4950862 4951986 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4950862..4951986) Methylobacterium extorquens DM4 8194356 YP_003070468.1 CDS mutM NC_012988.1 4952226 4953125 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4952226..4953125 Methylobacterium extorquens DM4 8194357 YP_003070469.1 CDS METDI5041 NC_012988.1 4953346 4953549 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4953346..4953549 Methylobacterium extorquens DM4 8195745 YP_003070470.1 CDS METDI5042 NC_012988.1 4953712 4954176 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, BadM/Rrf2 family 4953712..4954176 Methylobacterium extorquens DM4 8194358 YP_003070471.1 CDS METDI5043 NC_012988.1 4954166 4955074 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase 4954166..4955074 Methylobacterium extorquens DM4 8194359 YP_003070472.1 CDS METDI5044 NC_012988.1 4955370 4956929 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Penicillin-binding protein 4955370..4956929 Methylobacterium extorquens DM4 8194360 YP_003070473.1 CDS METDI5045 NC_012988.1 4957021 4959348 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hybrid histidine kinase with multiple PAS and a response regulator receiver domain complement(4957021..4959348) Methylobacterium extorquens DM4 8194361 YP_003070474.1 CDS METDI5046 NC_012988.1 4959478 4960206 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(4959478..4960206) Methylobacterium extorquens DM4 8194362 YP_003070475.1 CDS METDI5047 NC_012988.1 4960226 4960903 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4960226..4960903) Methylobacterium extorquens DM4 8194363 YP_003070476.1 CDS METDI5048 NC_012988.1 4960993 4961304 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4960993..4961304) Methylobacterium extorquens DM4 8194364 YP_003070477.1 CDS uvrB NC_012988.1 4961422 4964148 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(4961422..4964148) Methylobacterium extorquens DM4 8194365 YP_003070478.1 CDS METDI5050 NC_012988.1 4964295 4964543 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7961423; Product type f : factor; prevent-host-death protein 4964295..4964543 Methylobacterium extorquens DM4 8196330 YP_003070479.1 CDS METDI5051 NC_012988.1 4964540 4964926 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4964540..4964926 Methylobacterium extorquens DM4 8194366 YP_003070480.1 CDS METDI5052 NC_012988.1 4964933 4965844 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family complement(4964933..4965844) Methylobacterium extorquens DM4 8194367 YP_003070481.1 CDS METDI5053 NC_012988.1 4965966 4966361 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4965966..4966361 Methylobacterium extorquens DM4 8194368 YP_003070482.1 CDS METDI5054 NC_012988.1 4966402 4966884 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Biphenyl-2,3-diol 1,2-dioxygenase III 4966402..4966884 Methylobacterium extorquens DM4 8194369 YP_003070483.1 CDS METDI5055 NC_012988.1 4966963 4967640 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4966963..4967640 Methylobacterium extorquens DM4 8194370 YP_003070484.1 CDS METDI5056 NC_012988.1 4967576 4968070 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4967576..4968070 Methylobacterium extorquens DM4 8194371 YP_003070485.1 CDS uppS NC_012988.1 4968190 4968852 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 4968190..4968852 Methylobacterium extorquens DM4 8194372 YP_003070486.1 CDS bchE NC_012988.1 4968942 4970468 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase (Mg-protoporphyrin IX monomethyl ester oxidative cyclase) 4968942..4970468 Methylobacterium extorquens DM4 8196307 YP_003070487.1 CDS METDI5059 NC_012988.1 4970540 4971082 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4970540..4971082 Methylobacterium extorquens DM4 8195128 YP_003070488.1 CDS glpK NC_012988.1 4971170 4972675 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10090737, 8170944, 9817843, 9843423; Product type e : enzyme; glycerol kinase 4971170..4972675 Methylobacterium extorquens DM4 8194373 YP_003070489.1 CDS METDI5061 NC_012988.1 4972723 4973838 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 4972723..4973838 Methylobacterium extorquens DM4 8195508 YP_003070490.1 CDS METDI5062 NC_012988.1 4974044 4975729 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative methyl-accepting chemotaxis sensory transducer 4974044..4975729 Methylobacterium extorquens DM4 8194374 YP_003070491.1 CDS METDI5063 NC_012988.1 4975795 4976556 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycerophosphoryl diester phosphodiesterase complement(4975795..4976556) Methylobacterium extorquens DM4 8194375 YP_003070492.1 CDS METDI5064 NC_012988.1 4976553 4977026 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Endoribonuclease L-PSP complement(4976553..4977026) Methylobacterium extorquens DM4 8194376 YP_003070493.1 CDS METDI5065 NC_012988.1 4977299 4979470 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11679081, 2249654, 9743528, 9864332; Product type pt : putative transporter; putative bacteriocin/pheromone secretion/processing ATP-binding protein complement(4977299..4979470) Methylobacterium extorquens DM4 8194377 YP_003070494.1 CDS METDI5066 NC_012988.1 4979467 4980756 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative secretion protein complement(4979467..4980756) Methylobacterium extorquens DM4 8194378 YP_003070495.1 CDS METDI5067 NC_012988.1 4981233 4981445 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4981233..4981445 Methylobacterium extorquens DM4 8194379 YP_003070496.1 CDS METDI5068 NC_012988.1 4981780 4982682 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4981780..4982682 Methylobacterium extorquens DM4 8194380 YP_003070497.1 CDS argD NC_012988.1 4982896 4984086 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent 4982896..4984086 Methylobacterium extorquens DM4 8194381 YP_003070498.1 CDS argF NC_012988.1 4984073 4985065 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; ornithine carbamoyltransferase 4984073..4985065 Methylobacterium extorquens DM4 8195085 YP_003070499.1 CDS METDI5071 NC_012988.1 4985124 4985363 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4985124..4985363) Methylobacterium extorquens DM4 8195087 YP_003070500.1 CDS METDI5072 NC_012988.1 4985508 4985975 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4985508..4985975) Methylobacterium extorquens DM4 8194382 YP_003070501.1 CDS METDI5073 NC_012988.1 4985995 4986417 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4985995..4986417) Methylobacterium extorquens DM4 8194383 YP_003070502.1 CDS METDI5074 NC_012988.1 4986703 4987509 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1556094, 9100384; Product type pe : putative enzyme; putative 3-ketoacyl-acyl carrier protein reductase (fabG-like) 4986703..4987509 Methylobacterium extorquens DM4 8194384 YP_003070503.1 CDS METDI5075 NC_012988.1 4987513 4988895 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1339281, 1581034; Product type pe : putative enzyme; putative dihydrolipoamide dehydrogenase 4987513..4988895 Methylobacterium extorquens DM4 8194385 YP_003070504.1 CDS METDI5076 NC_012988.1 4989119 4991746 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Bacteriophytochrome (light-regulated signal transduction histidine kinase), PhyB2 4989119..4991746 Methylobacterium extorquens DM4 8194386 YP_003070505.1 CDS METDI5077 NC_012988.1 4991754 4992311 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Heme oxygenase (BphO-like) 4991754..4992311 Methylobacterium extorquens DM4 8194387 YP_003070506.1 CDS METDI5078 NC_012988.1 4992377 4993537 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4992377..4993537) Methylobacterium extorquens DM4 8194388 YP_003070507.1 CDS METDI5079 NC_012988.1 4993530 4994012 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4993530..4994012) Methylobacterium extorquens DM4 8194389 YP_003070508.1 CDS METDI5080 NC_012988.1 4994268 4995614 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative capsule polysaccharide export inner-membrane protein (kpsE-like) 4994268..4995614 Methylobacterium extorquens DM4 8194390 YP_003070509.1 CDS METDI5081 NC_012988.1 4995769 4996053 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4995769..4996053 Methylobacterium extorquens DM4 8194391 YP_003070510.1 CDS METDI5082 NC_012988.1 4996245 4997225 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4996245..4997225 Methylobacterium extorquens DM4 8194392 YP_003070511.1 CDS flbD NC_012988.1 4997258 4998631 R Evidence 2b : Function of strongly homologous gene; PubMedId : 17572072, 2315326; Product type r : regulator; two-component flagellar sigma-54 dependent transcriptional regulator, Fis family complement(4997258..4998631) Methylobacterium extorquens DM4 8194393 YP_003070512.1 CDS fliY NC_012988.1 4998785 4999132 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1732219, 2315326, 8002583; Product type s : structure; flagellar motor switch protein complement(4998785..4999132) Methylobacterium extorquens DM4 8195387 YP_003070513.1 CDS fliH NC_012988.1 4999138 4999764 R binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H complement(4999138..4999764) Methylobacterium extorquens DM4 8195431 YP_003070514.1 CDS fliG NC_012988.1 4999761 5000816 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G complement(4999761..5000816) Methylobacterium extorquens DM4 8194394 YP_003070515.1 CDS fliF NC_012988.1 5000860 5002482 R the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein complement(5000860..5002482) Methylobacterium extorquens DM4 8195418 YP_003070516.1 CDS METDI5088 NC_012988.1 5002743 5003018 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5002743..5003018) Methylobacterium extorquens DM4 8195416 YP_003070517.1 CDS METDI5089 NC_012988.1 5003160 5003840 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative flagellar basal-body rod modification protein (Synonyms : FlgD flaV, fla FIV, fla FVI) complement(5003160..5003840) Methylobacterium extorquens DM4 8194395 YP_003070518.1 CDS METDI5090 NC_012988.1 5003850 5005310 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative flagellar hook length determination protein complement(5003850..5005310) Methylobacterium extorquens DM4 8194396 YP_003070519.1 CDS mnmA NC_012988.1 5005509 5006741 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 5005509..5006741 Methylobacterium extorquens DM4 8194397 YP_003070520.1 CDS METDI5092 NC_012988.1 5006997 5007653 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphatidylethanolamine-N-methyltransferase (pmtA) 5006997..5007653 Methylobacterium extorquens DM4 8196213 YP_003070521.1 CDS METDI5093 NC_012988.1 5007692 5008540 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5007692..5008540 Methylobacterium extorquens DM4 8194398 YP_003070522.1 CDS METDI5094 NC_012988.1 5008714 5010198 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase 5008714..5010198 Methylobacterium extorquens DM4 8194399 YP_003070523.1 CDS emrB NC_012988.1 5011312 5012889 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; multidrug efflux system protein complement(5011312..5012889) Methylobacterium extorquens DM4 8194401 YP_003070524.1 CDS METDI5097 NC_012988.1 5013086 5014291 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1409590; Product type pt : putative transporter; putative multidrug resistance secretion protein (emrA-like) complement(5013086..5014291) Methylobacterium extorquens DM4 8195328 YP_003070525.1 CDS METDI5098 NC_012988.1 5014432 5015094 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, TetR family 5014432..5015094 Methylobacterium extorquens DM4 8194402 YP_003070526.1 CDS METDI5099 NC_012988.1 5015101 5016864 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12039753; Product type e : enzyme; acyl-CoA dehydrogenase complement(5015101..5016864) Methylobacterium extorquens DM4 8194403 YP_003070527.1 CDS METDI5100 NC_012988.1 5016975 5017964 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5016975..5017964 Methylobacterium extorquens DM4 8194404 YP_003070528.1 CDS METDI5101 NC_012988.1 5018134 5019948 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hybrid histidine kinase; HK, ATPase, PAS and a response regulator receiver domain complement(5018134..5019948) Methylobacterium extorquens DM4 8194405 YP_003070529.1 CDS METDI5102 NC_012988.1 5019887 5020222 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12622725, 12727878, 12727879, 14709675, 15071498, 15170179; Product type e : enzyme; thiol disulfide isomerase complement(5019887..5020222) Methylobacterium extorquens DM4 8194406 YP_003070530.1 CDS METDI5103 NC_012988.1 5020219 5020626 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12622725, 12727878, 12727879, 14709675, 15071498, 15170179; Product type e : enzyme; thiol disulfide isomerase complement(5020219..5020626) Methylobacterium extorquens DM4 8194407 YP_003070531.1 CDS METDI5104 NC_012988.1 5020623 5022350 R acts as a promotor non-specific transcription repressor; circadian clock protein KaiC complement(5020623..5022350) Methylobacterium extorquens DM4 8194408 YP_003070532.1 CDS METDI5105 NC_012988.1 5022767 5023153 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) 5022767..5023153 Methylobacterium extorquens DM4 8194409 YP_003070533.1 CDS METDI5106 NC_012988.1 5023176 5024522 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative integral membrane sensor signal transduction histidine kinase precursor complement(5023176..5024522) Methylobacterium extorquens DM4 8194410 YP_003070534.1 CDS METDI5107 NC_012988.1 5024519 5025184 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative phoP: DNA-binding response regulator in two-component regulatory system with PhoQ complement(5024519..5025184) Methylobacterium extorquens DM4 8194411 YP_003070535.1 CDS METDI5108 NC_012988.1 5025209 5025541 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5025209..5025541) Methylobacterium extorquens DM4 8194412 YP_003070536.1 CDS METDI5109 NC_012988.1 5025708 5026343 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5025708..5026343 Methylobacterium extorquens DM4 8194413 YP_003070537.1 CDS METDI5110 NC_012988.1 5026359 5026652 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5026359..5026652) Methylobacterium extorquens DM4 8194414 YP_003070538.1 CDS METDI5111 NC_012988.1 5026652 5027002 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5026652..5027002) Methylobacterium extorquens DM4 8194415 YP_003070539.1 CDS METDI5112 NC_012988.1 5026999 5028591 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5026999..5028591) Methylobacterium extorquens DM4 8194416 YP_003070540.1 CDS METDI5113 NC_012988.1 5028588 5028902 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5028588..5028902) Methylobacterium extorquens DM4 8194417 YP_003070541.1 CDS METDI5114 NC_012988.1 5028912 5031269 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative TonB-dependent siderophore receptor complement(5028912..5031269) Methylobacterium extorquens DM4 8194418 YP_003070542.1 CDS METDI5115 NC_012988.1 5031511 5031789 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5031511..5031789) Methylobacterium extorquens DM4 8194419 YP_003070543.1 CDS METDI5116 NC_012988.1 5032207 5032377 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5032207..5032377) Methylobacterium extorquens DM4 8194420 YP_003070544.1 CDS METDI5117 NC_012988.1 5032437 5032628 D Evidence 5 : No homology to any previously reported sequences; PubMedId : 9163424; hypothetical protein 5032437..5032628 Methylobacterium extorquens DM4 8194421 YP_003070545.1 CDS METDI5118 NC_012988.1 5033142 5038703 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5033142..5038703 Methylobacterium extorquens DM4 8194422 YP_003070546.1 CDS METDI5119 NC_012988.1 5038781 5040304 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Phosphomannomutase/phosphoglucomutase (AlgC) 5038781..5040304 Methylobacterium extorquens DM4 8194423 YP_003070547.1 CDS METDI5120 NC_012988.1 5040714 5042207 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5040714..5042207 Methylobacterium extorquens DM4 8194424 YP_003070548.1 CDS METDI5121 NC_012988.1 5042583 5044010 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5042583..5044010 Methylobacterium extorquens DM4 8194425 YP_003070549.1 CDS METDI5122 NC_012988.1 5044164 5044424 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5044164..5044424) Methylobacterium extorquens DM4 8194426 YP_003070550.1 CDS METDI5123 NC_012988.1 5044424 5046628 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Tyrosine-protein kinase etk complement(5044424..5046628) Methylobacterium extorquens DM4 8194427 YP_003070551.1 CDS METDI5124 NC_012988.1 5046699 5048222 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Undecaprenyl-phosphate galactosephosphotransferase complement(5046699..5048222) Methylobacterium extorquens DM4 8194428 YP_003070552.1 CDS gme NC_012988.1 5048283 5049230 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11752432, 12954627, 16366586; Product type e : enzyme; GDP-mannose 3,5-epimerase complement(5048283..5049230) Methylobacterium extorquens DM4 8194429 YP_003070553.1 CDS METDI5126 NC_012988.1 5049663 5050442 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative N-acetylmannosaminyltransferase tagA complement(5049663..5050442) Methylobacterium extorquens DM4 8195522 YP_003070554.1 CDS METDI5127 NC_012988.1 5050439 5051440 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar nucleotide dehydratase complement(5050439..5051440) Methylobacterium extorquens DM4 8194430 YP_003070555.1 CDS METDI5128 NC_012988.1 5051896 5053263 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative OMA family outer membrane saccharide export protein 5051896..5053263 Methylobacterium extorquens DM4 8194431 YP_003070556.1 CDS METDI5129 NC_012988.1 5053316 5054725 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 5053316..5054725 Methylobacterium extorquens DM4 8194432 YP_003070557.1 CDS METDI5130 NC_012988.1 5054735 5055124 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5054735..5055124 Methylobacterium extorquens DM4 8194433 YP_003070558.1 CDS mxaB NC_012988.1 5055314 5055991 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type r : regulator; MxaB complement(5055314..5055991) Methylobacterium extorquens DM4 8194434 YP_003070559.1 CDS mxaH NC_012988.1 5055988 5056587 R Evidence 4 : Homologs of previously reported genes of unknown function; MxaH complement(5055988..5056587) Methylobacterium extorquens DM4 8195749 YP_003070560.1 CDS mxaE NC_012988.1 5056584 5057528 R Evidence 4 : Homologs of previously reported genes of unknown function; MxaE complement(5056584..5057528) Methylobacterium extorquens DM4 8195755 YP_003070561.1 CDS mxaD NC_012988.1 5057553 5058083 R Evidence 4 : Homologs of previously reported genes of unknown function; MxaD protein precursor complement(5057553..5058083) Methylobacterium extorquens DM4 8195752 YP_003070562.1 CDS mxaL NC_012988.1 5058083 5059093 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; MxaL protein precursor complement(5058083..5059093) Methylobacterium extorquens DM4 8195751 YP_003070563.1 CDS mxaK NC_012988.1 5059090 5059716 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; MxaK protein complement(5059090..5059716) Methylobacterium extorquens DM4 8195759 YP_003070564.1 CDS mxaC NC_012988.1 5059716 5060783 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; MxaC protein complement(5059716..5060783) Methylobacterium extorquens DM4 8195758 YP_003070565.1 CDS mxaA NC_012988.1 5060788 5061711 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; MxaA protein complement(5060788..5061711) Methylobacterium extorquens DM4 8195750 YP_003070566.1 CDS mxaS NC_012988.1 5061717 5062586 R Evidence 1c : Function experimentally demonstrated in the studied genus; hypothetical protein complement(5061717..5062586) Methylobacterium extorquens DM4 8195748 YP_003070567.1 CDS mxaR NC_012988.1 5062583 5063614 R Evidence 1c : Function experimentally demonstrated in the studied genus; Protein MxaR (Protein MoxR) complement(5062583..5063614) Methylobacterium extorquens DM4 8195761 YP_003070568.1 CDS mxaI NC_012988.1 5063763 5064053 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 11502173, 2504152, 2842733, 7656012, 7735834; Product type e : enzyme; Methanol dehydrogenase subunit 2 precursor (MDH small beta subunit) complement(5063763..5064053) Methylobacterium extorquens DM4 8195760 YP_003070569.1 CDS mxaG NC_012988.1 5064159 5064752 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; Cytochrome c-L precursor complement(5064159..5064752) Methylobacterium extorquens DM4 8195756 YP_003070570.1 CDS mxaJ NC_012988.1 5064895 5065797 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 2116368; MxaJ complement(5064895..5065797) Methylobacterium extorquens DM4 8195754 YP_003070571.1 CDS mxaF NC_012988.1 5066061 5067905 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 2504152; Product type e : enzyme; Methanol dehydrogenase subunit 1 precursor (MDH large alpha subunit) (MEDH) complement(5066061..5067905) Methylobacterium extorquens DM4 8195757 YP_003070572.1 CDS mxaW NC_012988.1 5068312 5069217 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5068312..5069217 Methylobacterium extorquens DM4 8195753 YP_003070573.1 CDS METDI5147 NC_012988.1 5069367 5069564 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5069367..5069564 Methylobacterium extorquens DM4 8195762 YP_003070574.1 CDS METDI5148 NC_012988.1 5069596 5070330 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5069596..5070330) Methylobacterium extorquens DM4 8194435 YP_003070575.1 CDS METDI5149 NC_012988.1 5070676 5071575 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9495022; Product type pe : putative enzyme; putative metallo-hydrolase/oxidoreductase, beta-lactamase domain protein 5070676..5071575 Methylobacterium extorquens DM4 8194436 YP_003070576.1 CDS METDI5150 NC_012988.1 5071587 5072114 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5071587..5072114 Methylobacterium extorquens DM4 8194437 YP_003070577.1 CDS METDI5151 NC_012988.1 5072111 5072290 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5072111..5072290 Methylobacterium extorquens DM4 8194438 YP_003070578.1 CDS METDI5152 NC_012988.1 5072508 5073893 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9495022; Product type pe : putative enzyme; putative glmU-like gene; bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); glucosamine-1-phosphate acetyl transferase (C-terminal) 5072508..5073893 Methylobacterium extorquens DM4 8194439 YP_003070579.1 CDS glmS NC_012988.1 5074078 5075904 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091662, 3134953, 8805567, 9739095; Product type e : enzyme; L-glutamine:D-fructose-6-phosphate aminotransferase 5074078..5075904 Methylobacterium extorquens DM4 8194440 YP_003070580.1 CDS METDI5154 NC_012988.1 5075966 5076400 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16926146; hypothetical protein complement(5075966..5076400) Methylobacterium extorquens DM4 8195495 YP_003070581.1 CDS METDI5155 NC_012988.1 5076582 5077427 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6129240; hypothetical protein 5076582..5077427 Methylobacterium extorquens DM4 8194441 YP_003070582.1 CDS METDI5156 NC_012988.1 5077450 5077776 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5077450..5077776) Methylobacterium extorquens DM4 8194442 YP_003070583.1 CDS recG NC_012988.1 5078132 5080321 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(5078132..5080321) Methylobacterium extorquens DM4 8194443 YP_003070584.1 CDS METDI5158 NC_012988.1 5080513 5080809 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15593094; hypothetical protein 5080513..5080809 Methylobacterium extorquens DM4 8195970 YP_003070585.1 CDS mfd NC_012988.1 5081023 5084613 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8465200; Product type pe : putative enzyme; transcription repair coupling protein, ATP-dependent helicase 5081023..5084613 Methylobacterium extorquens DM4 8194444 YP_003070586.1 CDS cspE NC_012988.1 5084990 5085199 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; DNA-binding transcriptional repressor 5084990..5085199 Methylobacterium extorquens DM4 8195692 YP_003070587.1 CDS METDI5161 NC_012988.1 5085302 5085670 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5085302..5085670 Methylobacterium extorquens DM4 8195225 YP_003070588.1 CDS METDI5162 NC_012988.1 5085849 5086046 D Evidence 6 : Doubtful CDS; hypothetical protein 5085849..5086046 Methylobacterium extorquens DM4 8194445 YP_003070589.1 CDS METDI5164 NC_012988.1 5086113 5086454 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5086113..5086454) Methylobacterium extorquens DM4 8194446 YP_003070590.1 CDS METDI5165 NC_012988.1 5086712 5088016 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5086712..5088016) Methylobacterium extorquens DM4 8194447 YP_003070591.1 CDS METDI5166 NC_012988.1 5088356 5089663 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; integral membrane sensor signal transduction histidine kinase 5088356..5089663 Methylobacterium extorquens DM4 8194448 YP_003070592.1 CDS METDI5167 NC_012988.1 5089865 5090227 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator; CheY-like protein 5089865..5090227 Methylobacterium extorquens DM4 8194449 YP_003070593.1 CDS METDI5168 NC_012988.1 5090241 5090537 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp : cell process; putative Plasmid stabilisation system protein complement(5090241..5090537) Methylobacterium extorquens DM4 8194450 YP_003070594.1 CDS METDI5169 NC_012988.1 5090516 5090752 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5090516..5090752) Methylobacterium extorquens DM4 8194451 YP_003070595.1 CDS METDI5170 NC_012988.1 5090787 5092424 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AMP-dependent synthetase/acyl-CoA ligase complement(5090787..5092424) Methylobacterium extorquens DM4 8194452 YP_003070596.1 CDS METDI5171 NC_012988.1 5092563 5092757 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5092563..5092757) Methylobacterium extorquens DM4 8194453 YP_003070597.1 CDS METDI5172 NC_012988.1 5093007 5094815 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase, putative membrane protein 5093007..5094815 Methylobacterium extorquens DM4 8194454 YP_003070598.1 CDS METDI5173 NC_012988.1 5094812 5095585 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12459482; Product type e : enzyme; glycosyl transferase 5094812..5095585 Methylobacterium extorquens DM4 8194455 YP_003070599.1 CDS METDI5174 NC_012988.1 5095590 5095919 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5095590..5095919 Methylobacterium extorquens DM4 8194456 YP_003070600.1 CDS METDI5175 NC_012988.1 5095935 5096402 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5095935..5096402 Methylobacterium extorquens DM4 8194457 YP_003070601.1 CDS METDI5176 NC_012988.1 5096403 5097914 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative flavin-binding monooxygenase complement(5096403..5097914) Methylobacterium extorquens DM4 8194458 YP_003070602.1 CDS METDI5177 NC_012988.1 5097911 5098831 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Acetyl-hydrolase complement(5097911..5098831) Methylobacterium extorquens DM4 8194459 YP_003070603.1 CDS METDI5178 NC_012988.1 5098828 5099652 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR ; putative exported protein complement(5098828..5099652) Methylobacterium extorquens DM4 8194460 YP_003070604.1 CDS METDI5179 NC_012988.1 5099660 5101156 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5099660..5101156) Methylobacterium extorquens DM4 8194461 YP_003070605.1 CDS METDI5180 NC_012988.1 5101324 5101503 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5101324..5101503 Methylobacterium extorquens DM4 8194462 YP_003070606.1 CDS METDI5181 NC_012988.1 5101510 5101911 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5101510..5101911 Methylobacterium extorquens DM4 8194463 YP_003070607.1 CDS METDI5182 NC_012988.1 5101928 5102860 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8867604; Product type pm : putative membrane component; hypothetical protein 5101928..5102860 Methylobacterium extorquens DM4 8194464 YP_003070608.1 CDS METDI5183 NC_012988.1 5103181 5104197 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transmembrane histidine kinase, putaive HK and ATPase domain but no sensory domain detected 5103181..5104197 Methylobacterium extorquens DM4 8194465 YP_003070609.1 CDS METDI5184 NC_012988.1 5104571 5105374 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8141782; Product type pe : putative enzyme; putative lipolytic enzyme, putative esterase, G-D-S-L family 5104571..5105374 Methylobacterium extorquens DM4 8194466 YP_003070610.1 CDS METDI5185 NC_012988.1 5105442 5105834 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5105442..5105834 Methylobacterium extorquens DM4 8194467 YP_003070611.1 CDS METDI5186 NC_012988.1 5105943 5106773 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal-dependent hydrolase complement(5105943..5106773) Methylobacterium extorquens DM4 8194468 YP_003070612.1 CDS METDI5187 NC_012988.1 5106790 5107587 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9546395; Product type pe : putative enzyme; putative metallo-dependent hydrolase, putative deoxyribonuclease, TatD family complement(5106790..5107587) Methylobacterium extorquens DM4 8194469 YP_003070613.1 CDS metG NC_012988.1 5107637 5109205 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9607323; Product type e : enzyme; methionyl-tRNA synthetase complement(5107637..5109205) Methylobacterium extorquens DM4 8194470 YP_003070614.1 CDS METDI5189 NC_012988.1 5109431 5109646 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5109431..5109646) Methylobacterium extorquens DM4 8195683 YP_003070615.1 CDS METDI5190 NC_012988.1 5109944 5110144 D Evidence 6 : Doubtful CDS; hypothetical protein 5109944..5110144 Methylobacterium extorquens DM4 8194471 YP_003070616.1 CDS holB NC_012988.1 5110192 5111274 R Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; DNA polymerase III, delta prime subunit complement(5110192..5111274) Methylobacterium extorquens DM4 8194472 YP_003070617.1 CDS tmk NC_012988.1 5111264 5111998 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; thymidylate kinase complement(5111264..5111998) Methylobacterium extorquens DM4 8195570 YP_003070618.1 CDS potI NC_012988.1 5112053 5112832 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; putrescine transporter, membrane component of ABC transporter complement(5112053..5112832) Methylobacterium extorquens DM4 8196201 YP_003070619.1 CDS potH NC_012988.1 5112829 5113836 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; putrescine transporter, membrane component of ABC transporter complement(5112829..5113836) Methylobacterium extorquens DM4 8195878 YP_003070620.1 CDS potG NC_012988.1 5113833 5114918 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; putrescine transporter, ATP-binding component of ABC transporter complement(5113833..5114918) Methylobacterium extorquens DM4 8195877 YP_003070621.1 CDS METDI5196 NC_012988.1 5115007 5115711 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10403406, 15066032, 20020724, 4367415, 92232655, 93126385, 93345806; Product type pr : putative regulator; putative DNA-binding transcriptional dual regulator complement(5115007..5115711) Methylobacterium extorquens DM4 8195876 YP_003070622.1 CDS METDI5197 NC_012988.1 5116145 5116393 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5116145..5116393) Methylobacterium extorquens DM4 8194473 YP_003070623.1 CDS METDI5198 NC_012988.1 5116510 5119236 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5116510..5119236 Methylobacterium extorquens DM4 8194474 YP_003070624.1 CDS METDI5199 NC_012988.1 5119319 5119552 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5119319..5119552 Methylobacterium extorquens DM4 8194475 YP_003070625.1 CDS METDI5200 NC_012988.1 5119637 5120026 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5119637..5120026 Methylobacterium extorquens DM4 8194476 YP_003070626.1 CDS METDI5201 NC_012988.1 5120064 5121365 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator superfamily complement(5120064..5121365) Methylobacterium extorquens DM4 8194477 YP_003070627.1 CDS sga NC_012988.1 5121455 5122630 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11309139, 8898880; Product type e : enzyme; serine-glyoxylate aminotransferase complement(5121455..5122630) Methylobacterium extorquens DM4 8194478 YP_003070628.1 CDS METDI5203 NC_012988.1 5122794 5123573 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10068799, 10930734; Product type pr : putative regulator; putative transcriptional regulator, GntR family 5122794..5123573 Methylobacterium extorquens DM4 8196116 YP_003070629.1 CDS hyi NC_012988.1 5123629 5124405 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10561547; Product type e : enzyme; hydroxypyruvate isomerase 5123629..5124405 Methylobacterium extorquens DM4 8194479 YP_003070630.1 CDS METDI5205 NC_012988.1 5124521 5125393 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3082854; Product type pe : putative enzyme; putative glucose dehydrogenase, NAD(P)-binding domain complement(5124521..5125393) Methylobacterium extorquens DM4 8195583 YP_003070631.1 CDS METDI5206 NC_012988.1 5125470 5128442 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative D-lactate dehydrogenase (cytochrome) complement(5125470..5128442) Methylobacterium extorquens DM4 8194480 YP_003070632.1 CDS depB NC_012988.1 5128625 5129989 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; PHB depolymerase complement(5128625..5129989) Methylobacterium extorquens DM4 8194481 YP_003070633.1 CDS METDI5208 NC_012988.1 5130290 5131723 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10543838, 13680097; Product type e : enzyme; succinate-semialdehyde dehydrogenase I, NADP-dependent (gabD-like) complement(5130290..5131723) Methylobacterium extorquens DM4 8195290 YP_003070634.1 CDS METDI5209 NC_012988.1 5131887 5132927 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5131887..5132927) Methylobacterium extorquens DM4 8194482 YP_003070635.1 CDS METDI5210 NC_012988.1 5133263 5133442 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5133263..5133442) Methylobacterium extorquens DM4 8194483 YP_003070636.1 CDS METDI5211 NC_012988.1 5133763 5135334 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5133763..5135334 Methylobacterium extorquens DM4 8194484 YP_003070637.1 CDS METDI5212 NC_012988.1 5135331 5136662 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5135331..5136662 Methylobacterium extorquens DM4 8194485 YP_003070638.1 CDS METDI5213 NC_012988.1 5137257 5137562 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative flagellar motor switch protein FliN complement(5137257..5137562) Methylobacterium extorquens DM4 8196241 YP_003070639.1 CDS lipB NC_012988.1 5137705 5138355 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Lipoyltransferase (Lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferase) (Lipoate-protein ligase B) 5137705..5138355 Methylobacterium extorquens DM4 8194487 YP_003070640.1 CDS METDI5215 NC_012988.1 5138481 5139641 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase complement(5138481..5139641) Methylobacterium extorquens DM4 8195637 YP_003070641.1 CDS METDI5216 NC_012988.1 5139887 5140333 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5139887..5140333 Methylobacterium extorquens DM4 8194488 YP_003070642.1 CDS METDI5217 NC_012988.1 5140352 5142310 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative membrane transport protein complement(5140352..5142310) Methylobacterium extorquens DM4 8194489 YP_003070643.1 CDS METDI5218 NC_012988.1 5142539 5142913 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver complement(5142539..5142913) Methylobacterium extorquens DM4 8194490 YP_003070644.1 CDS METDI5219 NC_012988.1 5143086 5144447 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5143086..5144447 Methylobacterium extorquens DM4 8194491 YP_003070645.1 CDS METDI5220 NC_012988.1 5144531 5146942 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hybrid histidine kinase; Domains: two PAS, two PAC, His KinaseA, ATPase and two REC (CheY-like) 5144531..5146942 Methylobacterium extorquens DM4 8194492 YP_003070646.1 CDS METDI5221 NC_012988.1 5147058 5148437 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Regulatory protein, GntR:Aminotransferase, class I and II complement(5147058..5148437) Methylobacterium extorquens DM4 8194493 YP_003070647.1 CDS METDI5222 NC_012988.1 5148595 5149482 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5148595..5149482 Methylobacterium extorquens DM4 8194494 YP_003070648.1 CDS METDI5223 NC_012988.1 5149495 5150229 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; two-component response regulator complement(5149495..5150229) Methylobacterium extorquens DM4 8194495 YP_003070649.1 CDS METDI5224 NC_012988.1 5150355 5150885 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative GCN5-related N-acetyltransferase complement(5150355..5150885) Methylobacterium extorquens DM4 8194496 YP_003070650.1 CDS METDI5225 NC_012988.1 5151073 5151516 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5151073..5151516 Methylobacterium extorquens DM4 8194497 YP_003070651.1 CDS glcA NC_012988.1 5151588 5153327 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11283302, 11785976, 15919996; Product type t : transporter; glycolate permease (LctP family) complement(5151588..5153327) Methylobacterium extorquens DM4 8194498 YP_003070652.1 CDS cat NC_012988.1 5153700 5154623 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9989945; Product type e : enzyme; Manganese catalase 5153700..5154623 Methylobacterium extorquens DM4 8195486 YP_003070653.1 CDS METDI5228 NC_012988.1 5154687 5155583 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8917308; Product type e : enzyme; terpenoid synthase, putative phytoene synthase complement(5154687..5155583) Methylobacterium extorquens DM4 8195148 YP_003070654.1 CDS METDI5229 NC_012988.1 5155717 5156112 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5155717..5156112) Methylobacterium extorquens DM4 8194499 YP_003070655.1 CDS METDI5230 NC_012988.1 5156237 5157181 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; hypothetical protein complement(5156237..5157181) Methylobacterium extorquens DM4 8194500 YP_003070656.1 CDS METDI5231 NC_012988.1 5157281 5158879 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; hypothetical protein complement(5157281..5158879) Methylobacterium extorquens DM4 8194501 YP_003070657.1 CDS yajC NC_012988.1 5158947 5159279 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12941162, 9826342; Product type t : transporter; preprotein translocase, auxillary membrane component (General Secretory Pathway), YajC subunit complement(5158947..5159279) Methylobacterium extorquens DM4 8194502 YP_003070658.1 CDS METDI5233 NC_012988.1 5159765 5160655 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5159765..5160655 Methylobacterium extorquens DM4 8196348 YP_003070659.1 CDS METDI5234 NC_012988.1 5160801 5162168 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(5160801..5162168) Methylobacterium extorquens DM4 8194503 YP_003070660.1 CDS pcm NC_012988.1 5162370 5163068 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; L-isoaspartate protein carboxylmethyltransferase type II complement(5162370..5163068) Methylobacterium extorquens DM4 8194504 YP_003070661.1 CDS surE NC_012988.1 5163093 5163857 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(5163093..5163857) Methylobacterium extorquens DM4 8195835 YP_003070662.1 CDS serS NC_012988.1 5163857 5165143 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(5163857..5165143) Methylobacterium extorquens DM4 8196176 YP_003070663.1 CDS pqqA NC_012988.1 5165625 5165714 D Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis; probably provides the glutamate and tyrosine residues that are cross-linked and modified to form the coenzyme; coenzyme PQQ synthesis protein PqqA 5165625..5165714 Methylobacterium extorquens DM4 8196113 YP_003070664.1 CDS METDI5239 NC_012988.1 5166023 5166541 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8672816, 9023225, 9501442; Product type pr : putative regulator; putative transcriptional regulator, MarR family complement(5166023..5166541) Methylobacterium extorquens DM4 8195888 YP_003070665.1 CDS METDI5240 NC_012988.1 5166703 5167170 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5166703..5167170) Methylobacterium extorquens DM4 8194505 YP_003070666.1 CDS METDI5241 NC_012988.1 5167167 5168327 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enoyl-CoA hydratase/isomerase family protein complement(5167167..5168327) Methylobacterium extorquens DM4 8194506 YP_003070667.1 CDS hemB NC_012988.1 5168985 5170040 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 5168985..5170040 Methylobacterium extorquens DM4 8194507 YP_003070668.1 CDS METDI5243 NC_012988.1 5170081 5170482 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5170081..5170482 Methylobacterium extorquens DM4 8195549 YP_003070669.1 CDS METDI5244 NC_012988.1 5170595 5171089 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5170595..5171089 Methylobacterium extorquens DM4 8194508 YP_003070670.1 CDS ate NC_012988.1 5171228 5171974 D Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 5171228..5171974 Methylobacterium extorquens DM4 8194509 YP_003070671.1 CDS METDI5246 NC_012988.1 5172061 5172387 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5172061..5172387 Methylobacterium extorquens DM4 8195112 YP_003070672.1 CDS METDI5247 NC_012988.1 5172387 5172704 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5172387..5172704 Methylobacterium extorquens DM4 8194510 YP_003070673.1 CDS maa NC_012988.1 5172739 5173302 R Evidence 2b : Function of strongly homologous gene; PubMedId : 82180540, 91310703, 9600841; Product type e : enzyme; maltose o-acetyltransferase complement(5172739..5173302) Methylobacterium extorquens DM4 8194511 YP_003070674.1 CDS METDI5249 NC_012988.1 5173330 5174235 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5173330..5174235) Methylobacterium extorquens DM4 8195658 YP_003070675.1 CDS METDI5250 NC_012988.1 5174341 5175375 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phage DNA polymerase complement(5174341..5175375) Methylobacterium extorquens DM4 8194512 YP_003070676.1 CDS etfD NC_012988.1 5175587 5177260 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12815589, 8306995, 9294455; Product type e : enzyme; electron transfer flavoprotein ubiquinone oxidoreductase 5175587..5177260 Methylobacterium extorquens DM4 8194513 YP_003070677.1 CDS METDI5252 NC_012988.1 5177353 5178342 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5177353..5178342) Methylobacterium extorquens DM4 8195336 YP_003070678.1 CDS METDI5253 NC_012988.1 5178339 5179223 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative RarD-like membrane protein, putative chloramphenicol resistance permease complement(5178339..5179223) Methylobacterium extorquens DM4 8194514 YP_003070679.1 CDS METDI5254 NC_012988.1 5179281 5179568 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5179281..5179568) Methylobacterium extorquens DM4 8194515 YP_003070680.1 CDS METDI5255 NC_012988.1 5179711 5179875 D Evidence 6 : Doubtful CDS; hypothetical protein 5179711..5179875 Methylobacterium extorquens DM4 8194516 YP_003070681.1 CDS metC NC_012988.1 5179972 5181159 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8831789; Product type e : enzyme; cystathionine beta-lyase, PLP-dependent (beta-cystathionase) 5179972..5181159 Methylobacterium extorquens DM4 8194517 YP_003070682.1 CDS METDI5257 NC_012988.1 5181537 5182709 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative zinc-containing alcohol dehydrogenase 5181537..5182709 Methylobacterium extorquens DM4 8195681 YP_003070683.1 CDS METDI5258 NC_012988.1 5182781 5183386 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5182781..5183386 Methylobacterium extorquens DM4 8194518 YP_003070684.1 CDS METDI5259 NC_012988.1 5183408 5184502 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5183408..5184502 Methylobacterium extorquens DM4 8194519 YP_003070685.1 CDS METDI5260 NC_012988.1 5184741 5185337 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative pyridoxamine 5'-phosphate oxidase-related, FMN-binding complement(5184741..5185337) Methylobacterium extorquens DM4 8194520 YP_003070686.1 CDS METDI5261 NC_012988.1 5185745 5189023 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensor hybrid histidine kinase with multiple PAS/PAC and response regulator receiver domains 5185745..5189023 Methylobacterium extorquens DM4 8194521 YP_003070687.1 CDS METDI5262 NC_012988.1 5189057 5191285 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glycosyl transferase, family 2 complement(5189057..5191285) Methylobacterium extorquens DM4 8194522 YP_003070688.1 CDS pcm NC_012988.1 5192039 5192659 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; L-isoaspartate O-methyltransferase (protein beta-aspartate methyltransferase, protein L-isoaspartyl methyltransferase, L-isoaspartyl protein carboxyl methyltransferase) 5192039..5192659 Methylobacterium extorquens DM4 8194523 YP_003070689.1 CDS ibpA NC_012988.1 5192890 5193393 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8808920; Product type f : factor; small heat shock protein 5192890..5193393 Methylobacterium extorquens DM4 8195836 YP_003070690.1 CDS METDI5265 NC_012988.1 5193498 5194007 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5193498..5194007 Methylobacterium extorquens DM4 8195586 YP_003070691.1 CDS mutL NC_012988.1 5194070 5196058 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12271122; Product type e : enzyme; DNA mismatch repair protein mutL complement(5194070..5196058) Methylobacterium extorquens DM4 8194524 YP_003070692.1 CDS METDI5267 NC_012988.1 5196275 5197501 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11812788, 2777793, 8759838; Product type pe : putative enzyme; putative Short-chain specific acyl-CoA dehydrogenase complement(5196275..5197501) Methylobacterium extorquens DM4 8195744 YP_003070693.1 CDS METDI5268 NC_012988.1 5197641 5199506 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-binding protein with two ATPase domains, ABC transporter related 5197641..5199506 Methylobacterium extorquens DM4 8194525 YP_003070694.1 CDS METDI5269 NC_012988.1 5199903 5200934 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Alpha/beta hydrolase related 5199903..5200934 Methylobacterium extorquens DM4 8194526 YP_003070695.1 CDS METDI5270 NC_012988.1 5200910 5201626 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative deaminase reductase domain-containing protein complement(5200910..5201626) Methylobacterium extorquens DM4 8194527 YP_003070696.1 CDS METDI5271 NC_012988.1 5201775 5202227 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5201775..5202227 Methylobacterium extorquens DM4 8194528 YP_003070697.1 CDS METDI5272 NC_012988.1 5202297 5202734 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5202297..5202734 Methylobacterium extorquens DM4 8194529 YP_003070698.1 CDS METDI5273 NC_012988.1 5203164 5204762 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter protein, periplasmic substrate-binding component (tat pathway signal) 5203164..5204762 Methylobacterium extorquens DM4 8194530 YP_003070699.1 CDS oppB NC_012988.1 5204759 5205682 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2187863, 86111606, 93106975; Product type t : transporter; oligopeptide transporter subunit ; membrane component of ABC superfamily 5204759..5205682 Methylobacterium extorquens DM4 8194531 YP_003070700.1 CDS METDI5275 NC_012988.1 5205679 5206770 D Evidence 2b : Function of strongly homologous gene; Product type c : carrier; ABC transporter, permease protein, putative oligopeptide transport system permease protein, oppC-related 5205679..5206770 Methylobacterium extorquens DM4 8195811 YP_003070701.1 CDS METDI5276 NC_012988.1 5206778 5207068 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5206778..5207068) Methylobacterium extorquens DM4 8194532 YP_003070702.1 CDS METDI5277 NC_012988.1 5207200 5208678 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Major facilitator superfamily MFS-1, putative sugar transport protein 5207200..5208678 Methylobacterium extorquens DM4 8194533 YP_003070703.1 CDS METDI5278 NC_012988.1 5208941 5209531 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5208941..5209531) Methylobacterium extorquens DM4 8194534 YP_003070704.1 CDS METDI5279 NC_012988.1 5209671 5210369 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5209671..5210369) Methylobacterium extorquens DM4 8194535 YP_003070705.1 CDS METDI5280 NC_012988.1 5210601 5211539 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, LysR family complement(5210601..5211539) Methylobacterium extorquens DM4 8194536 YP_003070706.1 CDS wrbA NC_012988.1 5211740 5212339 D stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 5211740..5212339 Methylobacterium extorquens DM4 8194537 YP_003070707.1 CDS METDI5282 NC_012988.1 5212401 5214545 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative thiol:disulfide interchange protein precursor complement(5212401..5214545) Methylobacterium extorquens DM4 8196335 YP_003070708.1 CDS mutS NC_012988.1 5214738 5217524 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12887908, 1938937, 88032849, 89112166, 92291095, 99410452; Product type e : enzyme; DNA mismatch repair protein mutS complement(5214738..5217524) Methylobacterium extorquens DM4 8194538 YP_003070709.1 CDS METDI5284 NC_012988.1 5217691 5218008 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5217691..5218008) Methylobacterium extorquens DM4 8195746 YP_003070710.1 CDS hrpB NC_012988.1 5218191 5220680 D Evidence 2b : Function of strongly homologous gene; PubMedId : 95206938; Product type e : enzyme; helicase, ATP-dependent 5218191..5220680 Methylobacterium extorquens DM4 8194539 YP_003070711.1 CDS METDI5286 NC_012988.1 5220637 5221350 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5220637..5221350) Methylobacterium extorquens DM4 8195577 YP_003070712.1 CDS METDI5287 NC_012988.1 5221551 5221922 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5221551..5221922 Methylobacterium extorquens DM4 8194540 YP_003070713.1 CDS METDI5288 NC_012988.1 5221935 5222330 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10882093, 16926146; Product type pe : putative enzyme; putative lactoylglutathione lyase complement(5221935..5222330) Methylobacterium extorquens DM4 8194541 YP_003070714.1 CDS xerC NC_012988.1 5222452 5223549 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10744667, 7715441; Product type e : enzyme; ptyrosine recombinase xerC, integrase/recombinase Ripx (xerC) 5222452..5223549 Methylobacterium extorquens DM4 8194542 YP_003070715.1 CDS METDI5290 NC_012988.1 5223649 5223783 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5223649..5223783 Methylobacterium extorquens DM4 8196337 YP_003070716.1 CDS METDI5291 NC_012988.1 5223866 5224462 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphoglycerate mutase complement(5223866..5224462) Methylobacterium extorquens DM4 8194543 YP_003070717.1 CDS METDI5292 NC_012988.1 5224638 5225642 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5224638..5225642 Methylobacterium extorquens DM4 8194544 YP_003070718.1 CDS METDI5293 NC_012988.1 5225731 5226888 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5225731..5226888 Methylobacterium extorquens DM4 8194545 YP_003070719.1 CDS METDI5294 NC_012988.1 5226890 5227579 D Evidence 4 : Homologs of previously reported genes of unknown function; MOSC domain protein, YiiM-like protein 5226890..5227579 Methylobacterium extorquens DM4 8194546 YP_003070720.1 CDS fabI NC_012988.1 5227583 5228410 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10398587, 2687243; Product type e : enzyme; Enoyl-[acyl-carrier-protein] reductase (NADH) complement(5227583..5228410) Methylobacterium extorquens DM4 8194547 YP_003070721.1 CDS METDI5296 NC_012988.1 5228648 5229580 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10092456, 9276481, 9349721; Product type f : factor; Chaperone DnaJ domain protein, putative heat shock protein complement(5228648..5229580) Methylobacterium extorquens DM4 8195349 YP_003070722.1 CDS METDI5297 NC_012988.1 5229732 5230274 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5229732..5230274) Methylobacterium extorquens DM4 8194548 YP_003070723.1 CDS pdxH NC_012988.1 5230427 5231005 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12878029, 14515321; Product type e : enzyme; pyridoxine 5'-phosphate oxidase 5230427..5231005 Methylobacterium extorquens DM4 8194549 YP_003070724.1 CDS METDI5299 NC_012988.1 5231040 5231423 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) complement(5231040..5231423) Methylobacterium extorquens DM4 8195841 YP_003070725.1 CDS fixR1 NC_012988.1 5231734 5232459 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3313281; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR 5231734..5232459 Methylobacterium extorquens DM4 8194550 YP_003070726.1 CDS METDI5301 NC_012988.1 5232452 5233603 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15602564, 9352903; hypothetical protein 5232452..5233603 Methylobacterium extorquens DM4 8195385 YP_003070727.1 CDS METDI5302 NC_012988.1 5233600 5234085 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative GDP-mannose mannosyl hydrolase (nudD) 5233600..5234085 Methylobacterium extorquens DM4 8194551 YP_003070728.1 CDS METDI5303 NC_012988.1 5234082 5234537 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5234082..5234537 Methylobacterium extorquens DM4 8194552 YP_003070729.1 CDS METDI5304 NC_012988.1 5234877 5235131 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5234877..5235131 Methylobacterium extorquens DM4 8194553 YP_003070730.1 CDS METDI5305 NC_012988.1 5235330 5236901 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5235330..5236901) Methylobacterium extorquens DM4 8194554 YP_003070731.1 CDS pyrC NC_012988.1 5237203 5238540 R Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase complement(5237203..5238540) Methylobacterium extorquens DM4 8194555 YP_003070732.1 CDS METDI5307 NC_012988.1 5238642 5239496 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Glycine cleavage T protein (aminomethyl transferase) 5238642..5239496 Methylobacterium extorquens DM4 8195948 YP_003070733.1 CDS tag NC_012988.1 5239493 5240122 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3536912; Product type e : enzyme; 3-methyl-adenine DNA glycosylase I 5239493..5240122 Methylobacterium extorquens DM4 8194556 YP_003070734.1 CDS METDI5309 NC_012988.1 5240119 5240745 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8282711, 8759915, 9210332; Product type e : enzyme; Metal-dependent phosphohydrolase 5240119..5240745 Methylobacterium extorquens DM4 8196178 YP_003070735.1 CDS METDI5310 NC_012988.1 5240760 5241272 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5240760..5241272 Methylobacterium extorquens DM4 8194557 YP_003070736.1 CDS xseB NC_012988.1 5241372 5241638 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; exodeoxyribonuclease VII small subunit (exonuclease VII small subunit) 5241372..5241638 Methylobacterium extorquens DM4 8194558 YP_003070737.1 CDS dxs NC_012988.1 5241728 5243704 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 5241728..5243704 Methylobacterium extorquens DM4 8196344 YP_003070738.1 CDS sod NC_012988.1 5243750 5244370 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11136448, 2345128, 7589534, 7786035, 7929223, 8626323, 9003353, 9405149; Product type e : enzyme; Superoxide dismutase [Cu-Zn] precursor complement(5243750..5244370) Methylobacterium extorquens DM4 8195322 YP_003070739.1 CDS tly NC_012988.1 5244715 5245467 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9611795; Product type e : enzyme; hemolysin 5244715..5245467 Methylobacterium extorquens DM4 8196119 YP_003070740.1 CDS rumA NC_012988.1 5245479 5246762 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 23S rRNA (Uracil-5-)-methyltransferase 5245479..5246762 Methylobacterium extorquens DM4 8196200 YP_003070741.1 CDS METDI5316 NC_012988.1 5246836 5248080 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5246836..5248080) Methylobacterium extorquens DM4 8196091 YP_003070742.1 CDS METDI5317 NC_012988.1 5248396 5249391 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12003941, 8636017; hypothetical protein 5248396..5249391 Methylobacterium extorquens DM4 8194559 YP_003070743.1 CDS METDI5318 NC_012988.1 5249404 5250135 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5249404..5250135) Methylobacterium extorquens DM4 8194560 YP_003070744.1 CDS METDI5319 NC_012988.1 5250417 5251637 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5250417..5251637 Methylobacterium extorquens DM4 8194561 YP_003070745.1 CDS METDI5320 NC_012988.1 5251634 5252791 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7730270; Product type e : enzyme; amidohydrolase 5251634..5252791 Methylobacterium extorquens DM4 8194562 YP_003070746.1 CDS ada NC_012988.1 5253042 5254127 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; fused DNA-binding transcriptional dual regulator ; O6-methylguanine-DNA methyltransferase 5253042..5254127 Methylobacterium extorquens DM4 8194563 YP_003070747.1 CDS METDI5322 NC_012988.1 5254132 5255154 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12215815, 2678100, 8829543; Product type pt : putative transporter; putative cation transport protein complement(5254132..5255154) Methylobacterium extorquens DM4 8195062 YP_003070748.1 CDS METDI5323 NC_012988.1 5255276 5255704 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine triad family protein, putative nucleoside phosphate hydrolase 5255276..5255704 Methylobacterium extorquens DM4 8194564 YP_003070749.1 CDS METDI5324 NC_012988.1 5255760 5256206 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5255760..5256206) Methylobacterium extorquens DM4 8194565 YP_003070750.1 CDS METDI5325 NC_012988.1 5256288 5256536 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5256288..5256536) Methylobacterium extorquens DM4 8194566 YP_003070751.1 CDS METDI5326 NC_012988.1 5256650 5256835 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5256650..5256835) Methylobacterium extorquens DM4 8194567 YP_003070752.1 CDS METDI5327 NC_012988.1 5256802 5258685 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glucoamylase or glycosyl hydrolase protein complement(5256802..5258685) Methylobacterium extorquens DM4 8194568 YP_003070753.1 CDS METDI5328 NC_012988.1 5258777 5259055 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5258777..5259055) Methylobacterium extorquens DM4 8194569 YP_003070754.1 CDS METDI5329 NC_012988.1 5259118 5260275 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative N-acetylglucosamine-6-phosphate deacetylase (nagA-like) complement(5259118..5260275) Methylobacterium extorquens DM4 8194570 YP_003070755.1 CDS METDI5330 NC_012988.1 5260382 5261392 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glucosamine-fructose-6-phosphate aminotransferase (gmlS-like) complement(5260382..5261392) Methylobacterium extorquens DM4 8194571 YP_003070756.1 CDS murQ NC_012988.1 5261389 5262276 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase complement(5261389..5262276) Methylobacterium extorquens DM4 8194572 YP_003070757.1 CDS METDI5332 NC_012988.1 5262530 5263357 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative endonuclease/exonuclease/phosphatase 5262530..5263357 Methylobacterium extorquens DM4 8194573 YP_003070758.1 CDS METDI5333 NC_012988.1 5263436 5264503 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative periplasmic L-asparaginase (ansB) 5263436..5264503 Methylobacterium extorquens DM4 8194574 YP_003070759.1 CDS METDI5334 NC_012988.1 5264620 5266167 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phospholipase D/transphosphatidylase complement(5264620..5266167) Methylobacterium extorquens DM4 8194575 YP_003070760.1 CDS METDI5335 NC_012988.1 5266226 5266924 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5266226..5266924) Methylobacterium extorquens DM4 8194576 YP_003070761.1 CDS METDI5336 NC_012988.1 5267072 5267482 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5267072..5267482) Methylobacterium extorquens DM4 8194577 YP_003070762.1 CDS METDI5337 NC_012988.1 5267698 5268423 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10622737; Product type pm : putative membrane component; putative surfeit locus 1 family protein (surf1-like) complement(5267698..5268423) Methylobacterium extorquens DM4 8194578 YP_003070763.1 CDS cyoD NC_012988.1 5268485 5268865 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11017202; Product type e : enzyme; cytochrome o ubiquinol oxidase, subunit IV complement(5268485..5268865) Methylobacterium extorquens DM4 8194579 YP_003070764.1 CDS cyoC NC_012988.1 5268862 5269509 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11017202; Product type e : enzyme; cytochrome o ubiquinol oxidase, subunit III complement(5268862..5269509) Methylobacterium extorquens DM4 8195246 YP_003070765.1 CDS cyoB NC_012988.1 5269518 5271521 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11017202; Product type e : enzyme; cytochrome o ubiquinol oxidase, subunit I complement(5269518..5271521) Methylobacterium extorquens DM4 8195245 YP_003070766.1 CDS cyoA NC_012988.1 5271561 5272685 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11017202; Product type e : enzyme; cytochrome o ubiquinol oxidase subunit II complement(5271561..5272685) Methylobacterium extorquens DM4 8195244 YP_003070767.1 CDS METDI5342 NC_012988.1 5272919 5274253 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; MFS transporter membrane protein complement(5272919..5274253) Methylobacterium extorquens DM4 8195243 YP_003070768.1 CDS METDI5343 NC_012988.1 5274545 5277607 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; RND efflux transporter, AcrB/AcrD/AcrF family complement(5274545..5277607) Methylobacterium extorquens DM4 8194580 YP_003070769.1 CDS METDI5344 NC_012988.1 5277664 5278827 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; RND efflux transporter, membrane fusion protein subunit complement(5277664..5278827) Methylobacterium extorquens DM4 8194581 YP_003070770.1 CDS METDI5345 NC_012988.1 5278824 5279987 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; RND efflux transporter, membrane fusion protein subunit precursor complement(5278824..5279987) Methylobacterium extorquens DM4 8194582 YP_003070771.1 CDS METDI5346 NC_012988.1 5280207 5280767 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, TetR family 5280207..5280767 Methylobacterium extorquens DM4 8194583 YP_003070772.1 CDS METDI5347 NC_012988.1 5281087 5281791 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11158353; Product type pr : putative regulator; putative two-component transcriptional regulator, LuxR family complement(5281087..5281791) Methylobacterium extorquens DM4 8194584 YP_003070773.1 CDS METDI5348 NC_012988.1 5281799 5283013 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5281799..5283013) Methylobacterium extorquens DM4 8194585 YP_003070774.1 CDS METDI5349 NC_012988.1 5283316 5283741 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 1) 5283316..5283741 Methylobacterium extorquens DM4 8194586 YP_003070775.1 CDS METDI5350 NC_012988.1 5283753 5284070 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex15, IS5 family (ORF 2) 5283753..5284070 Methylobacterium extorquens DM4 8194587 YP_003070776.1 CDS METDI5351 NC_012988.1 5284541 5285191 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative two-component transcriptional regulator, LuxR family 5284541..5285191 Methylobacterium extorquens DM4 8194588 YP_003070777.1 CDS METDI5352 NC_012988.1 5285385 5286146 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative two-component transcriptional regulator, LuxR family 5285385..5286146 Methylobacterium extorquens DM4 8194589 YP_003070778.1 CDS METDI5353 NC_012988.1 5286241 5287059 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10482500; Product type pe : putative enzyme; putative glycosyl transferase 5286241..5287059 Methylobacterium extorquens DM4 8194590 YP_003070779.1 CDS METDI5354 NC_012988.1 5287229 5288413 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5287229..5288413 Methylobacterium extorquens DM4 8194591 YP_003070780.1 CDS METDI5356 NC_012988.1 5288827 5290635 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phage integrase 5288827..5290635 Methylobacterium extorquens DM4 8196255 YP_003070781.1 CDS METDI5357 NC_012988.1 5290662 5290877 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator complement(5290662..5290877) Methylobacterium extorquens DM4 8194593 YP_003070782.1 CDS METDI5358 NC_012988.1 5291030 5292280 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallo-beta-lactamase family protein 5291030..5292280 Methylobacterium extorquens DM4 8194594 YP_003070783.1 CDS METDI5359 NC_012988.1 5292277 5293356 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5292277..5293356 Methylobacterium extorquens DM4 8194595 YP_003070784.1 CDS METDI5360 NC_012988.1 5293665 5294495 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5293665..5294495 Methylobacterium extorquens DM4 8194596 YP_003070785.1 CDS METDI5361 NC_012988.1 5294518 5294952 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5294518..5294952 Methylobacterium extorquens DM4 8194597 YP_003070786.1 CDS METDI5362 NC_012988.1 5294883 5295674 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5294883..5295674 Methylobacterium extorquens DM4 8194598 YP_003070787.1 CDS METDI5363 NC_012988.1 5295872 5296150 D Evidence 6 : Doubtful CDS; hypothetical protein 5295872..5296150 Methylobacterium extorquens DM4 8194599 YP_003070788.1 CDS METDI5364 NC_012988.1 5296258 5300343 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5296258..5300343) Methylobacterium extorquens DM4 8194600 YP_003070789.1 CDS METDI5367 NC_012988.1 5301299 5302534 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5301299..5302534 Methylobacterium extorquens DM4 8194602 YP_003070790.1 CDS METDI5368 NC_012988.1 5302432 5302635 D Evidence 6 : Doubtful CDS; hypothetical protein 5302432..5302635 Methylobacterium extorquens DM4 8194603 YP_003070791.1 CDS METDI5369 NC_012988.1 5302712 5304574 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5302712..5304574 Methylobacterium extorquens DM4 8194604 YP_003070792.1 CDS METDI5370 NC_012988.1 5304697 5304930 D Evidence 6 : Doubtful CDS; hypothetical protein 5304697..5304930 Methylobacterium extorquens DM4 8194605 YP_003070793.1 CDS METDI5371 NC_012988.1 5305232 5305738 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5305232..5305738 Methylobacterium extorquens DM4 8194606 YP_003070794.1 CDS METDI5372 NC_012988.1 5305822 5311638 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA helicase related protein 5305822..5311638 Methylobacterium extorquens DM4 8194607 YP_003070795.1 CDS METDI5373 NC_012988.1 5311813 5312088 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5311813..5312088) Methylobacterium extorquens DM4 8194608 YP_003070796.1 CDS METDI5374 NC_012988.1 5312388 5313146 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5312388..5313146) Methylobacterium extorquens DM4 8194609 YP_003070797.1 CDS METDI5375 NC_012988.1 5314116 5315195 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative ardC antirestriction protein 5314116..5315195 Methylobacterium extorquens DM4 8194610 YP_003070798.1 CDS METDI5376 NC_012988.1 5314817 5315770 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5314817..5315770 Methylobacterium extorquens DM4 8194611 YP_003070799.1 CDS METDI5377 NC_012988.1 5315866 5318295 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5315866..5318295) Methylobacterium extorquens DM4 8194612 YP_003070800.1 CDS METDI5378 NC_012988.1 5318292 5320712 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5318292..5320712) Methylobacterium extorquens DM4 8194613 YP_003070801.1 CDS METDI5379 NC_012988.1 5320612 5321904 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5320612..5321904) Methylobacterium extorquens DM4 8194614 YP_003070802.1 CDS METDI5380 NC_012988.1 5322230 5322481 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5322230..5322481) Methylobacterium extorquens DM4 8194615 YP_003070803.1 CDS METDI5381 NC_012988.1 5322539 5322742 D Evidence 6 : Doubtful CDS; hypothetical protein 5322539..5322742 Methylobacterium extorquens DM4 8194616 YP_003070804.1 CDS METDI5382 NC_012988.1 5322960 5323463 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5322960..5323463 Methylobacterium extorquens DM4 8194617 YP_003070805.1 CDS METDI5383 NC_012988.1 5323497 5325260 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative protease/peptidase 5323497..5325260 Methylobacterium extorquens DM4 8194618 YP_003070806.1 CDS METDI5384 NC_012988.1 5325273 5326628 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5325273..5326628 Methylobacterium extorquens DM4 8194619 YP_003070807.1 CDS srfB NC_012988.1 5326679 5329789 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; virulence factor SrfB 5326679..5329789 Methylobacterium extorquens DM4 8194620 YP_003070808.1 CDS srfC NC_012988.1 5329786 5332443 D Evidence 2b : Function of strongly homologous gene; Product type f : factor; virulence factor SrfC 5329786..5332443 Methylobacterium extorquens DM4 8196145 YP_003070809.1 CDS METDI5387 NC_012988.1 5332406 5333551 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5332406..5333551 Methylobacterium extorquens DM4 8196146 YP_003070810.1 CDS METDI5388 NC_012988.1 5333620 5335422 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5333620..5335422 Methylobacterium extorquens DM4 8194621 YP_003070811.1 CDS METDI5389 NC_012988.1 5335460 5336044 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5335460..5336044 Methylobacterium extorquens DM4 8194622 YP_003070812.1 CDS METDI5390 NC_012988.1 5336259 5336993 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5336259..5336993 Methylobacterium extorquens DM4 8194623 YP_003070813.1 CDS ldhA NC_012988.1 5337583 5338593 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9025293; Product type e : enzyme; fermentative D-lactate dehydrogenase, NAD-dependent 5337583..5338593 Methylobacterium extorquens DM4 8194624 YP_003070814.1 CDS METDI5392 NC_012988.1 5338622 5339575 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, LysR family complement(5338622..5339575) Methylobacterium extorquens DM4 8195626 YP_003070815.1 CDS METDI5393 NC_012988.1 5339750 5339998 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5339750..5339998 Methylobacterium extorquens DM4 8194625 YP_003070816.1 CDS METDI5394 NC_012988.1 5340065 5340805 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5340065..5340805 Methylobacterium extorquens DM4 8194626 YP_003070817.1 CDS METDI5395 NC_012988.1 5340875 5341774 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5340875..5341774) Methylobacterium extorquens DM4 8194627 YP_003070818.1 CDS METDI5396 NC_012988.1 5341771 5342745 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11532010; Product type pe : putative enzyme; putative glycerate dehydrogenase (gyaR-like) complement(5341771..5342745) Methylobacterium extorquens DM4 8194628 YP_003070819.1 CDS METDI5397 NC_012988.1 5342712 5342999 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5342712..5342999) Methylobacterium extorquens DM4 8194629 YP_003070820.1 CDS leuC NC_012988.1 5343020 5344429 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 5343020..5344429 Methylobacterium extorquens DM4 8194630 YP_003070821.1 CDS METDI5399 NC_012988.1 5344836 5345024 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5344836..5345024 Methylobacterium extorquens DM4 8196240 YP_003070822.1 CDS METDI5400 NC_012988.1 5345178 5345456 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5345178..5345456 Methylobacterium extorquens DM4 8194631 YP_003070823.1 CDS METDI5401 NC_012988.1 5345523 5346122 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, TetR family complement(5345523..5346122) Methylobacterium extorquens DM4 8194632 YP_003070824.1 CDS METDI5402 NC_012988.1 5346217 5347482 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9044268; Product type t : transporter; RND efflux transporter, membrane fusion protein subunit 5346217..5347482 Methylobacterium extorquens DM4 8194633 YP_003070825.1 CDS METDI5403 NC_012988.1 5347582 5350776 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9044268; Product type t : transporter; RND efflux transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 5347582..5350776 Methylobacterium extorquens DM4 8194634 YP_003070826.1 CDS METDI5404 NC_012988.1 5351235 5351837 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, TetR family 5351235..5351837 Methylobacterium extorquens DM4 8194635 YP_003070827.1 CDS METDI5405 NC_012988.1 5352014 5352697 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5352014..5352697 Methylobacterium extorquens DM4 8194636 YP_003070828.1 CDS METDI5406 NC_012988.1 5352627 5352872 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5352627..5352872) Methylobacterium extorquens DM4 8194637 YP_003070829.1 CDS METDI5408 NC_012988.1 5353375 5354061 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Zn-dependent protease complement(5353375..5354061) Methylobacterium extorquens DM4 8194639 YP_003070830.1 CDS METDI5409 NC_012988.1 5354046 5354159 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5354046..5354159) Methylobacterium extorquens DM4 8194640 YP_003070831.1 CDS METDI5410 NC_012988.1 5354284 5355900 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase complement(5354284..5355900) Methylobacterium extorquens DM4 8194641 YP_003070832.1 CDS METDI5411 NC_012988.1 5356196 5357092 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5356196..5357092) Methylobacterium extorquens DM4 8194642 YP_003070833.1 CDS METDI5412 NC_012988.1 5357256 5357834 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5357256..5357834 Methylobacterium extorquens DM4 8194643 YP_003070834.1 CDS METDI5413 NC_012988.1 5358253 5359515 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD binding site:Amine oxidase complement(5358253..5359515) Methylobacterium extorquens DM4 8194644 YP_003070835.1 CDS inh NC_012988.1 5359719 5360549 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12244065; Product type e : enzyme; isonitrile hydratase precursor, ThiJ/PfpI family protein 5359719..5360549 Methylobacterium extorquens DM4 8194645 YP_003070836.1 CDS METDI5415 NC_012988.1 5360996 5361424 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16926146; hypothetical protein complement(5360996..5361424) Methylobacterium extorquens DM4 8195602 YP_003070837.1 CDS METDI5417 NC_012988.1 5361636 5362661 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein; putative sulfonate-binding protein precursor 5361636..5362661 Methylobacterium extorquens DM4 8194646 YP_003070838.1 CDS METDI5418 NC_012988.1 5362681 5363433 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative aliphatic sulfonates transport permease protein ssuC 5362681..5363433 Methylobacterium extorquens DM4 8194647 YP_003070839.1 CDS ssuB NC_012988.1 5363430 5364191 D Evidence 2b : Function of strongly homologous gene; PubMedId : 20245523, 3549459, 7984428, 99410391, 99436146; Product type t : transporter; alkanesulfonate transporter subunit ; ATP-binding component of ABC superfamily 5363430..5364191 Methylobacterium extorquens DM4 8194648 YP_003070840.1 CDS METDI5420 NC_012988.1 5364304 5364738 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5364304..5364738 Methylobacterium extorquens DM4 8196157 YP_003070841.1 CDS METDI5421 NC_012988.1 5364878 5365069 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5364878..5365069 Methylobacterium extorquens DM4 8194649 YP_003070842.1 CDS prfC NC_012988.1 5365372 5366991 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7737996, 8016068, 8016077, 8575429, 94286525, 94286535; Product type f : factor; peptide chain release factor RF-3; GTP-binding factor complement(5365372..5366991) Methylobacterium extorquens DM4 8194650 YP_003070843.1 CDS METDI5423 NC_012988.1 5367098 5367841 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(5367098..5367841) Methylobacterium extorquens DM4 8195896 YP_003070844.1 CDS METDI5424 NC_012988.1 5368468 5368956 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5368468..5368956) Methylobacterium extorquens DM4 8196256 YP_003070845.1 CDS METDI5425 NC_012988.1 5369324 5369800 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5369324..5369800 Methylobacterium extorquens DM4 8194652 YP_003070846.1 CDS tuf NC_012988.1 5370320 5371510 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(5370320..5371510) Methylobacterium extorquens DM4 8194653 YP_003070847.1 CDS METDI5428 NC_012988.1 5371633 5371908 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative ribosome-associated RNA-binding protein S4 paralog, putative heat-shock protein complement(5371633..5371908) Methylobacterium extorquens DM4 8196289 YP_003070848.1 CDS METDI5429 NC_012988.1 5371985 5375392 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8550440; hypothetical protein complement(5371985..5375392) Methylobacterium extorquens DM4 8194654 YP_003070849.1 CDS METDI5430 NC_012988.1 5375582 5375926 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5375582..5375926) Methylobacterium extorquens DM4 8194655 YP_003070850.1 CDS METDI5431 NC_012988.1 5376143 5377039 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5376143..5377039) Methylobacterium extorquens DM4 8194656 YP_003070851.1 CDS METDI5432 NC_012988.1 5377223 5378224 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7592399; Product type pe : putative enzyme; putative Glucokinase (Glucose kinase) complement(5377223..5378224) Methylobacterium extorquens DM4 8194657 YP_003070852.1 CDS METDI5433 NC_012988.1 5378315 5379070 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative trehalose-6-phosphate phosphatase (otsB) complement(5378315..5379070) Methylobacterium extorquens DM4 8194658 YP_003070853.1 CDS METDI5434 NC_012988.1 5379157 5379651 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5379157..5379651 Methylobacterium extorquens DM4 8194659 YP_003070854.1 CDS METDI5435 NC_012988.1 5379724 5380941 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Beta-lactamase 5379724..5380941 Methylobacterium extorquens DM4 8194660 YP_003070855.1 CDS METDI5436 NC_012988.1 5381158 5383089 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; transporter, betaine/carnitine/choline transporter (BCCT) family 5381158..5383089 Methylobacterium extorquens DM4 8194661 YP_003070856.1 CDS fdh2C NC_012988.1 5383581 5384054 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156; Product type e : enzyme; NAD-dependent formate dehydrogenase, Molybdenum containing, gamma subunit 5383581..5384054 Methylobacterium extorquens DM4 8194662 YP_003070857.1 CDS fdh2B NC_012988.1 5384051 5385610 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156; Product type e : enzyme; NAD-dependent formate dehydrogenase, Molybdenum containing, beta subunit 5384051..5385610 Methylobacterium extorquens DM4 8195364 YP_003070858.1 CDS fdh2A NC_012988.1 5385623 5388475 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156; Product type e : enzyme; NAD-dependent formate dehydrogenase, molybdenum containing, alpha subunit 5385623..5388475 Methylobacterium extorquens DM4 8195363 YP_003070859.1 CDS fdh2D NC_012988.1 5388682 5388972 D Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12730156; Product type e : enzyme; NAD-linked formate dehydrogenase, Molybdenum containing, delta subunit 5388682..5388972 Methylobacterium extorquens DM4 8195362 YP_003070860.1 CDS METDI5441 NC_012988.1 5389064 5389999 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator, LysR family 5389064..5389999 Methylobacterium extorquens DM4 8195365 YP_003070861.1 CDS METDI5442 NC_012988.1 5390071 5390517 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5390071..5390517) Methylobacterium extorquens DM4 8194663 YP_003070862.1 CDS METDI5443 NC_012988.1 5390585 5391619 R Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; small GTP-binding protein, putative GTPase complement(5390585..5391619) Methylobacterium extorquens DM4 8194664 YP_003070863.1 CDS METDI5444 NC_012988.1 5391656 5392135 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5391656..5392135) Methylobacterium extorquens DM4 8194665 YP_003070864.1 CDS METDI5445 NC_012988.1 5392132 5392731 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase, putative N-acetylase of ribosomal proteins complement(5392132..5392731) Methylobacterium extorquens DM4 8194666 YP_003070865.1 CDS rpmA NC_012988.1 5392920 5393186 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(5392920..5393186) Methylobacterium extorquens DM4 8194667 YP_003070866.1 CDS rplU NC_012988.1 5393235 5393627 R Evidence 2b : Function of strongly homologous gene; Product type s : structure; 50S ribosomal protein L21 complement(5393235..5393627) Methylobacterium extorquens DM4 8196035 YP_003070867.1 CDS yjgR NC_012988.1 5393823 5395385 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enzyme with nucleoside triphosphate hydrolase domain complement(5393823..5395385) Methylobacterium extorquens DM4 8196030 YP_003070868.1 CDS METDI5450 NC_012988.1 5395540 5395926 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5395540..5395926 Methylobacterium extorquens DM4 8196371 YP_003070869.1 CDS METDI5451 NC_012988.1 5396079 5397137 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5396079..5397137 Methylobacterium extorquens DM4 8194668 YP_003070870.1 CDS METDI5452 NC_012988.1 5397115 5398383 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; permease of major facilitator transporter (tat pathway signal) 5397115..5398383 Methylobacterium extorquens DM4 8194669 YP_003070871.1 CDS METDI5453 NC_012988.1 5398485 5398613 D Evidence 6 : Doubtful CDS; hypothetical protein 5398485..5398613 Methylobacterium extorquens DM4 8194670 YP_003070872.1 CDS METDI5454 NC_012988.1 5398967 5399215 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5398967..5399215 Methylobacterium extorquens DM4 8194671 YP_003070873.1 CDS METDI5455 NC_012988.1 5399234 5400352 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative patatin-like phospholipase complement(5399234..5400352) Methylobacterium extorquens DM4 8194672 YP_003070874.1 CDS METDI5456 NC_012988.1 5400885 5401436 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5400885..5401436 Methylobacterium extorquens DM4 8194673 YP_003070875.1 CDS METDI5457 NC_012988.1 5401641 5401856 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5401641..5401856 Methylobacterium extorquens DM4 8194674 YP_003070876.1 CDS METDI5458 NC_012988.1 5401853 5402371 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5401853..5402371 Methylobacterium extorquens DM4 8194675 YP_003070877.1 CDS METDI5459 NC_012988.1 5402448 5403347 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diacylglycerol kinase related protein 5402448..5403347 Methylobacterium extorquens DM4 8194676 YP_003070878.1 CDS METDI5460 NC_012988.1 5403344 5404228 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metallophosphatase/metallophosphoesterase 5403344..5404228 Methylobacterium extorquens DM4 8194677 YP_003070879.1 CDS METDI5461 NC_012988.1 5404254 5405714 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium:solute symporter complement(5404254..5405714) Methylobacterium extorquens DM4 8194678 YP_003070880.1 CDS METDI5462 NC_012988.1 5405711 5405914 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; hypothetical protein complement(5405711..5405914) Methylobacterium extorquens DM4 8194679 YP_003070881.1 CDS METDI5463 NC_012988.1 5406093 5408204 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative PAS sensor hybrid histidine kinase complement(5406093..5408204) Methylobacterium extorquens DM4 8194680 YP_003070882.1 CDS METDI5464 NC_012988.1 5408401 5408850 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5408401..5408850) Methylobacterium extorquens DM4 8194681 YP_003070883.1 CDS METDI5465 NC_012988.1 5408912 5409658 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Nucleotidyl transferase complement(5408912..5409658) Methylobacterium extorquens DM4 8194682 YP_003070884.1 CDS METDI5466 NC_012988.1 5409692 5411320 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5409692..5411320) Methylobacterium extorquens DM4 8194683 YP_003070885.1 CDS METDI5467 NC_012988.1 5411578 5414121 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase, putative HK, ATPase and Sensor Domain complement(5411578..5414121) Methylobacterium extorquens DM4 8194684 YP_003070886.1 CDS ahcY NC_012988.1 5414611 5416017 R catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase complement(5414611..5416017) Methylobacterium extorquens DM4 8194685 YP_003070887.1 CDS METDI5469 NC_012988.1 5416187 5417875 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7934817; Product type e : enzyme; putative acetyl-coenzyme A synthetase (acsA-like) complement(5416187..5417875) Methylobacterium extorquens DM4 8195065 YP_003070888.1 CDS METDI5470 NC_012988.1 5417953 5418564 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme; putative oxidoreductase protein complement(5417953..5418564) Methylobacterium extorquens DM4 8194686 YP_003070889.1 CDS METDI5471 NC_012988.1 5418716 5419621 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10727085; Product type e : enzyme; enoyl-CoA hydratase 5418716..5419621 Methylobacterium extorquens DM4 8194687 YP_003070890.1 CDS METDI5472 NC_012988.1 5419728 5420507 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5419728..5420507 Methylobacterium extorquens DM4 8194688 YP_003070891.1 CDS cls NC_012988.1 5420398 5421834 R Evidence 2b : Function of strongly homologous gene; PubMedId : 12382061, 9370333; Product type e : enzyme; Cardiolipin synthase (cls-like) complement(5420398..5421834) Methylobacterium extorquens DM4 8194689 YP_003070892.1 CDS METDI5474 NC_012988.1 5422059 5425202 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5422059..5425202 Methylobacterium extorquens DM4 8195175 YP_003070893.1 CDS METDI5475 NC_012988.1 5425199 5428642 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative helicase-exonuclease type V protein family 5425199..5428642 Methylobacterium extorquens DM4 8194690 YP_003070894.1 CDS yliI NC_012988.1 5428738 5430024 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16864586; Product type e : enzyme; PQQ-dependent aldose sugar dehydrogenase precursor (asd), signal peptide complement(5428738..5430024) Methylobacterium extorquens DM4 8194691 YP_003070895.1 CDS METDI5477 NC_012988.1 5430077 5430412 D Evidence 6 : Doubtful CDS; hypothetical protein 5430077..5430412 Methylobacterium extorquens DM4 8196374 YP_003070896.1 CDS trx NC_012988.1 5430400 5430720 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16926146, 7021558, 90202710, 99175138; Product type e : enzyme; thioredoxin 5430400..5430720 Methylobacterium extorquens DM4 8194692 YP_003070897.1 CDS METDI5479 NC_012988.1 5430878 5431768 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative 31 kDa outer-membrane immunogenic protein precursor (omp31) complement(5430878..5431768) Methylobacterium extorquens DM4 8196284 YP_003070898.1 CDS folC NC_012988.1 5432157 5433482 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; bifunctional folylpolyglutamate synthase and dihydrofolate synthase complement(5432157..5433482) Methylobacterium extorquens DM4 8194693 YP_003070899.1 CDS accD NC_012988.1 5433515 5434438 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1355086, 16325142; Product type e : enzyme; acetyl-CoA carboxylase, carboxyltransferase subunit beta complement(5433515..5434438) Methylobacterium extorquens DM4 8195436 YP_003070900.1 CDS trpA NC_012988.1 5434549 5435391 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(5434549..5435391) Methylobacterium extorquens DM4 8195047 YP_003070901.1 CDS METDI5483 NC_012988.1 5435563 5436522 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleotide pyrophosphatase complement(5435563..5436522) Methylobacterium extorquens DM4 8196272 YP_003070902.1 CDS METDI5484 NC_012988.1 5436533 5436949 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative histidine triad (HIT) protein complement(5436533..5436949) Methylobacterium extorquens DM4 8194694 YP_003070903.1 CDS METDI5485 NC_012988.1 5437072 5438190 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal dependent phosphohydrolase with a response regulator receiver domain; HD-GYP domain protein 5437072..5438190 Methylobacterium extorquens DM4 8194695 YP_003070904.1 CDS METDI5486 NC_012988.1 5438530 5440236 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-independent RNA helicase, DEAD/DEAH-box family protein 5438530..5440236 Methylobacterium extorquens DM4 8194696 YP_003070905.1 CDS METDI5487 NC_012988.1 5440333 5441199 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5440333..5441199) Methylobacterium extorquens DM4 8194697 YP_003070906.1 CDS mxcQ NC_012988.1 5441666 5443153 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type r : regulator; integral membrane sensor signal transduction histidine kinase 5441666..5443153 Methylobacterium extorquens DM4 8194698 YP_003070907.1 CDS mxcE NC_012988.1 5443164 5443853 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type r : regulator; two component transcriptional regulator 5443164..5443853 Methylobacterium extorquens DM4 8195766 YP_003070908.1 CDS METDI5490 NC_012988.1 5443881 5444564 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional activator (TenA family) 5443881..5444564 Methylobacterium extorquens DM4 8195765 YP_003070909.1 CDS METDI5491 NC_012988.1 5444729 5446219 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino acid transporter 5444729..5446219 Methylobacterium extorquens DM4 8194699 YP_003070910.1 CDS METDI5492 NC_012988.1 5446420 5447325 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase of beta-lactamase superfamily complement(5446420..5447325) Methylobacterium extorquens DM4 8194700 YP_003070911.1 CDS METDI5493 NC_012988.1 5447517 5448662 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5447517..5448662) Methylobacterium extorquens DM4 8194701 YP_003070912.1 CDS METDI5494 NC_012988.1 5448830 5451433 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5448830..5451433) Methylobacterium extorquens DM4 8194702 YP_003070913.1 CDS METDI5495 NC_012988.1 5451819 5453810 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5451819..5453810 Methylobacterium extorquens DM4 8194703 YP_003070914.1 CDS METDI5496 NC_012988.1 5453807 5455036 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5453807..5455036 Methylobacterium extorquens DM4 8194704 YP_003070915.1 CDS METDI5497 NC_012988.1 5455095 5455916 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glutamine amidotransferase class II 5455095..5455916 Methylobacterium extorquens DM4 8194705 YP_003070916.1 CDS ecfG1 NC_012988.1 5456164 5456898 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type f : factor; RNA polymerase sigma factor 5456164..5456898 Methylobacterium extorquens DM4 8194706 YP_003070917.1 CDS METDI5499 NC_012988.1 5457628 5458161 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator (Ros/MucR family) complement(5457628..5458161) Methylobacterium extorquens DM4 8195323 YP_003070918.1 CDS METDI5500 NC_012988.1 5458533 5458931 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5458533..5458931) Methylobacterium extorquens DM4 8194707 YP_003070919.1 CDS METDI5501 NC_012988.1 5459029 5460342 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5459029..5460342 Methylobacterium extorquens DM4 8194708 YP_003070920.1 CDS METDI5502 NC_012988.1 5460563 5460883 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ferredoxin complement(5460563..5460883) Methylobacterium extorquens DM4 8194709 YP_003070921.1 CDS METDI5503 NC_012988.1 5461099 5461443 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5461099..5461443) Methylobacterium extorquens DM4 8194710 YP_003070922.1 CDS METDI5504 NC_012988.1 5461804 5470197 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5461804..5470197 Methylobacterium extorquens DM4 8194711 YP_003070923.1 CDS METDI5505 NC_012988.1 5470353 5470982 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, XRE family complement(5470353..5470982) Methylobacterium extorquens DM4 8194712 YP_003070924.1 CDS thiD NC_012988.1 5471159 5471965 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; bifunctional: hydroxy-methylpyrimidine kinase (HMP kinase); hydroxy-phosphomethylpyrimidine kinase (HMP-P kinase) complement(5471159..5471965) Methylobacterium extorquens DM4 8194713 YP_003070925.1 CDS thiE NC_012988.1 5472013 5472738 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; thiamine-phosphate pyrophosphorylase (TMP pyrophosphorylase) (TMP-PPase) (thiamine-phosphate synthase) complement(5472013..5472738) Methylobacterium extorquens DM4 8196186 YP_003070926.1 CDS METDI5508 NC_012988.1 5472864 5473970 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5472864..5473970 Methylobacterium extorquens DM4 8196188 YP_003070927.1 CDS METDI5509 NC_012988.1 5474036 5474311 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5474036..5474311) Methylobacterium extorquens DM4 8194714 YP_003070928.1 CDS METDI5511 NC_012988.1 5474628 5475158 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator (Ros/MucR family) complement(5474628..5475158) Methylobacterium extorquens DM4 8194715 YP_003070929.1 CDS argC NC_012988.1 5476094 5477038 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase complement(5476094..5477038) Methylobacterium extorquens DM4 8194716 YP_003070930.1 CDS METDI5513 NC_012988.1 5477294 5477833 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5477294..5477833 Methylobacterium extorquens DM4 8195084 YP_003070931.1 CDS modA NC_012988.1 5477886 5478695 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7860583, 8564363, 8576221, 90148107, 92011425, 9302996, 93368423; Product type t : transporter; molybdate ABC transporter, periplasmic molybdate-binding protein complement(5477886..5478695) Methylobacterium extorquens DM4 8194717 YP_003070932.1 CDS METDI5515 NC_012988.1 5478866 5479036 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5478866..5479036) Methylobacterium extorquens DM4 8195709 YP_003070933.1 CDS METDI5516 NC_012988.1 5479129 5479329 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5479129..5479329) Methylobacterium extorquens DM4 8194718 YP_003070934.1 CDS prmA NC_012988.1 5479654 5480571 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15317787; Product type e : enzyme; Ribosomal protein L11 methyltransferase (L11 Mtase) 5479654..5480571 Methylobacterium extorquens DM4 8194719 YP_003070935.1 CDS METDI5518 NC_012988.1 5480743 5482581 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aminopeptidase 5480743..5482581 Methylobacterium extorquens DM4 8195899 YP_003070936.1 CDS METDI5519 NC_012988.1 5482578 5483057 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7961734; Product type e : enzyme; phosphotyrosine protein phosphatase 5482578..5483057 Methylobacterium extorquens DM4 8194720 YP_003070937.1 CDS METDI5520 NC_012988.1 5483054 5483860 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase:kinase 5483054..5483860 Methylobacterium extorquens DM4 8194721 YP_003070938.1 CDS METDI5521 NC_012988.1 5484026 5486140 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused permease and ATPase components, putative membrane protein precursor complement(5484026..5486140) Methylobacterium extorquens DM4 8194722 YP_003070939.1 CDS METDI5523 NC_012988.1 5486414 5486743 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5486414..5486743) Methylobacterium extorquens DM4 8194723 YP_003070940.1 CDS METDI5524 NC_012988.1 5487035 5487691 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5487035..5487691 Methylobacterium extorquens DM4 8194724 YP_003070941.1 CDS METDI5525 NC_012988.1 5487699 5488616 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Pyridoxamine 5'-phosphate oxidase-related complement(5487699..5488616) Methylobacterium extorquens DM4 8194725 YP_003070942.1 CDS METDI5526 NC_012988.1 5488613 5489239 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase complement(5488613..5489239) Methylobacterium extorquens DM4 8194726 YP_003070943.1 CDS METDI5527 NC_012988.1 5489384 5490289 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9084165; Product type r : regulator; transcriptional regulator, LysR family 5489384..5490289 Methylobacterium extorquens DM4 8194727 YP_003070944.1 CDS METDI5528 NC_012988.1 5490318 5491922 R Catalyzes the reduction of sulfite to sulfide, an essential step in the anaerobic sulfate-respiration pathway; sulfite reductase complement(5490318..5491922) Methylobacterium extorquens DM4 8194728 YP_003070945.1 CDS nirA NC_012988.1 5491919 5493724 R ferredoxin-dependent assimilatory nitrite reductase; ferredoxin-nitrite reductase complement(5491919..5493724) Methylobacterium extorquens DM4 8194729 YP_003070946.1 CDS METDI5530 NC_012988.1 5493721 5494941 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase; putative nitrate or nitrite reductase subunit complement(5493721..5494941) Methylobacterium extorquens DM4 8194730 YP_003070947.1 CDS ntrCD NC_012988.1 5494967 5495761 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Nitrate transport ATP-binding subunits C and D complement(5494967..5495761) Methylobacterium extorquens DM4 8194731 YP_003070948.1 CDS nrtB NC_012988.1 5495774 5496634 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Nitrate transport permease protein complement(5495774..5496634) Methylobacterium extorquens DM4 8195785 YP_003070949.1 CDS nrtA NC_012988.1 5496631 5497923 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8437564, 8982006, 8990301; Product type t : transporter; nitrate transporter component complement(5496631..5497923) Methylobacterium extorquens DM4 8195782 YP_003070950.1 CDS METDI5534 NC_012988.1 5498254 5499270 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8437564, 8982006, 8990301; Product type pt : putative transporter; putative nitrate transporter component, nrtA complement(5498254..5499270) Methylobacterium extorquens DM4 8195780 YP_003070951.1 CDS METDI5535 NC_012988.1 5499267 5499854 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator: Input and output domains: CheY-like and ANTAR; a phospho receiver domain and an antitermination factor complement(5499267..5499854) Methylobacterium extorquens DM4 8194732 YP_003070952.1 CDS METDI5536 NC_012988.1 5500107 5500727 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5500107..5500727 Methylobacterium extorquens DM4 8194733 YP_003070953.1 CDS METDI5537 NC_012988.1 5500940 5502799 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11549021; Product type pe : putative enzyme; putative glycoside hydrolase 5500940..5502799 Methylobacterium extorquens DM4 8194734 YP_003070954.1 CDS tkt NC_012988.1 5502850 5504925 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15752350, 8396116; Product type e : enzyme; transketolase 5502850..5504925 Methylobacterium extorquens DM4 8194735 YP_003070955.1 CDS METDI5539 NC_012988.1 5505146 5507968 D catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; catalyzes isomerization of glucose 6-phosphate and fructose 6-phosphate; bifunctional transaldolase/phosoglucose isomerase 5505146..5507968 Methylobacterium extorquens DM4 8196199 YP_003070956.1 CDS METDI5540 NC_012988.1 5508283 5508927 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5508283..5508927) Methylobacterium extorquens DM4 8194736 YP_003070957.1 CDS METDI5541 NC_012988.1 5509011 5509217 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5509011..5509217) Methylobacterium extorquens DM4 8194737 YP_003070958.1 CDS METDI5542 NC_012988.1 5509349 5510809 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative methyl-accepting chemotaxis receptor/sensory transducer with PAS domain complement(5509349..5510809) Methylobacterium extorquens DM4 8194738 YP_003070959.1 CDS METDI5543 NC_012988.1 5511242 5512114 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5511242..5512114) Methylobacterium extorquens DM4 8194739 YP_003070960.1 CDS METDI5544 NC_012988.1 5512299 5513333 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Short-chain dehydrogenase/reductase SDR complement(5512299..5513333) Methylobacterium extorquens DM4 8194740 YP_003070961.1 CDS acrF NC_012988.1 5513500 5516709 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; multidrug transport protein, acriflavin resistance protein F (RND family) complement(5513500..5516709) Methylobacterium extorquens DM4 8194741 YP_003070962.1 CDS METDI5546 NC_012988.1 5516872 5518014 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; RND efflux transporter, membrane fusion protein subunit complement(5516872..5518014) Methylobacterium extorquens DM4 8195056 YP_003070963.1 CDS METDI5547 NC_012988.1 5518137 5518460 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme; rhodanese domain protein, putative sulfur transferase complement(5518137..5518460) Methylobacterium extorquens DM4 8194742 YP_003070964.1 CDS METDI5548 NC_012988.1 5518509 5519879 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glycosyl transferase, group 1 complement(5518509..5519879) Methylobacterium extorquens DM4 8194743 YP_003070965.1 CDS METDI5549 NC_012988.1 5519972 5520520 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5519972..5520520) Methylobacterium extorquens DM4 8194744 YP_003070966.1 CDS METDI5550 NC_012988.1 5520693 5521328 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11526037, 11814664, 12620866, 9922236; Product type e : enzyme; autoinducer (N-acylhomoserine lactone) synthase complement(5520693..5521328) Methylobacterium extorquens DM4 8194745 YP_003070967.1 CDS METDI5551 NC_012988.1 5521809 5522306 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; N-acylhomoserine lactone transcriptional regulator, LuxR family complement(5521809..5522306) Methylobacterium extorquens DM4 8194746 YP_003070968.1 CDS METDI5553 NC_012988.1 5523418 5523624 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5523418..5523624 Methylobacterium extorquens DM4 8194748 YP_003070969.1 CDS METDI5554 NC_012988.1 5523629 5523739 D Evidence 6 : Doubtful CDS; hypothetical protein 5523629..5523739 Methylobacterium extorquens DM4 8194749 YP_003070970.1 CDS METDI5555 NC_012988.1 5524184 5524333 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5524184..5524333 Methylobacterium extorquens DM4 8194750 YP_003070971.1 CDS METDI5556 NC_012988.1 5524351 5525727 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5524351..5525727) Methylobacterium extorquens DM4 8194751 YP_003070972.1 CDS METDI5557 NC_012988.1 5526250 5526594 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5526250..5526594 Methylobacterium extorquens DM4 8194752 YP_003070973.1 CDS METDI5558 NC_012988.1 5526673 5526855 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5526673..5526855 Methylobacterium extorquens DM4 8194753 YP_003070974.1 CDS METDI5559 NC_012988.1 5526913 5528229 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5526913..5528229 Methylobacterium extorquens DM4 8194754 YP_003070975.1 CDS METDI5562 NC_012988.1 5528946 5529239 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5528946..5529239 Methylobacterium extorquens DM4 8194757 YP_003070976.1 CDS METDI5563 NC_012988.1 5529398 5531077 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5529398..5531077) Methylobacterium extorquens DM4 8194758 YP_003070977.1 CDS METDI5564 NC_012988.1 5531267 5531377 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5531267..5531377) Methylobacterium extorquens DM4 8194759 YP_003070978.1 CDS METDI5565 NC_012988.1 5531384 5531878 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5531384..5531878 Methylobacterium extorquens DM4 8194760 YP_003070979.1 CDS METDI5568 NC_012988.1 5532807 5533766 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, LysR family complement(5532807..5533766) Methylobacterium extorquens DM4 8194762 YP_003070980.1 CDS METDI5569 NC_012988.1 5533863 5534114 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5533863..5534114 Methylobacterium extorquens DM4 8194763 YP_003070981.1 CDS METDI5570 NC_012988.1 5534257 5537451 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; AcrB/AcrD/AcrF family protein complement(5534257..5537451) Methylobacterium extorquens DM4 8194764 YP_003070982.1 CDS METDI5571 NC_012988.1 5537454 5538560 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5537454..5538560) Methylobacterium extorquens DM4 8194765 YP_003070983.1 CDS METDI5572 NC_012988.1 5538799 5539221 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5538799..5539221 Methylobacterium extorquens DM4 8194766 YP_003070984.1 CDS METDI5573 NC_012988.1 5539322 5539843 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5539322..5539843 Methylobacterium extorquens DM4 8194767 YP_003070985.1 CDS METDI5574 NC_012988.1 5539856 5541694 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Quinoprotein alcohol dehydrogenase complement(5539856..5541694) Methylobacterium extorquens DM4 8194768 YP_003070986.1 CDS METDI5576 NC_012988.1 5541885 5542157 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5541885..5542157 Methylobacterium extorquens DM4 8194769 YP_003070987.1 CDS METDI5577 NC_012988.1 5542202 5543347 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; signal transduction histidine kinase; GAF domain complement(5542202..5543347) Methylobacterium extorquens DM4 8194770 YP_003070988.1 CDS METDI5578 NC_012988.1 5543648 5544034 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5543648..5544034) Methylobacterium extorquens DM4 8194771 YP_003070989.1 CDS METDI5579 NC_012988.1 5544176 5546527 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldehyde dehydrogenase precursor (tat pathway signal) complement(5544176..5546527) Methylobacterium extorquens DM4 8194772 YP_003070990.1 CDS METDI5580 NC_012988.1 5546524 5547000 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8157655; Product type e : enzyme; oxidoreductase, 2Fe-2S subunit complement(5546524..5547000) Methylobacterium extorquens DM4 8194773 YP_003070991.1 CDS METDI5581 NC_012988.1 5547428 5547805 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5547428..5547805) Methylobacterium extorquens DM4 8194774 YP_003070992.1 CDS METDI5582 NC_012988.1 5548024 5548227 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5548024..5548227) Methylobacterium extorquens DM4 8194775 YP_003070993.1 CDS METDI5583 NC_012988.1 5548574 5548819 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5548574..5548819 Methylobacterium extorquens DM4 8194776 YP_003070994.1 CDS METDI5584 NC_012988.1 5548977 5551925 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphoenolpyruvate carboxylase complement(5548977..5551925) Methylobacterium extorquens DM4 8194777 YP_003070995.1 CDS METDI5585 NC_012988.1 5552052 5552618 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5552052..5552618 Methylobacterium extorquens DM4 8194778 YP_003070996.1 CDS METDI5586 NC_012988.1 5552615 5553487 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5552615..5553487 Methylobacterium extorquens DM4 8194779 YP_003070997.1 CDS METDI5587 NC_012988.1 5553496 5555169 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NAD(P)-binding dehydrogenase, putative saccharopine dehydrogenase 5553496..5555169 Methylobacterium extorquens DM4 8194780 YP_003070998.1 CDS METDI5588 NC_012988.1 5555166 5555606 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5555166..5555606 Methylobacterium extorquens DM4 8194781 YP_003070999.1 CDS METDI5589 NC_012988.1 5555741 5556958 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase precursor (tat pathway signal) 5555741..5556958 Methylobacterium extorquens DM4 8194782 YP_003071000.1 CDS METDI5590 NC_012988.1 5557047 5557490 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5557047..5557490 Methylobacterium extorquens DM4 8194783 YP_003071001.1 CDS METDI5591 NC_012988.1 5557823 5558710 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulatory protein, LysR family 5557823..5558710 Methylobacterium extorquens DM4 8194784 YP_003071002.1 CDS METDI5592 NC_012988.1 5558716 5559738 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; alcohol dehydrogenase complement(5558716..5559738) Methylobacterium extorquens DM4 8194785 YP_003071003.1 CDS METDI5593 NC_012988.1 5560098 5563307 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hybrid histidine kinase; Domains: two PAS, two PAC, two GAF, HWE histidine kinase, ATPase and REC (CheY-like) 5560098..5563307 Methylobacterium extorquens DM4 8194786 YP_003071004.1 CDS METDI5594 NC_012988.1 5563375 5563659 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5563375..5563659) Methylobacterium extorquens DM4 8194787 YP_003071005.1 CDS METDI5595 NC_012988.1 5563671 5564444 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11669613, 1556094; Product type e : enzyme; putative 3-oxoacyl-[acyl-carrier-protein] reductase (fabG-like) complement(5563671..5564444) Methylobacterium extorquens DM4 8194788 YP_003071006.1 CDS METDI5596 NC_012988.1 5564441 5565727 R FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-(acyl carrier protein) synthase II complement(5564441..5565727) Methylobacterium extorquens DM4 8194789 YP_003071007.1 CDS METDI5597 NC_012988.1 5565854 5566999 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(5565854..5566999) Methylobacterium extorquens DM4 8194790 YP_003071008.1 CDS METDI5598 NC_012988.1 5566996 5567460 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8910376; Product type e : enzyme; putative beta-hydroxyacyl-(acyl-carrier-protein) dehydratase (FabZ-like) complement(5566996..5567460) Methylobacterium extorquens DM4 8194791 YP_003071009.1 CDS acpXL NC_012988.1 5567489 5567785 R Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein complement(5567489..5567785) Methylobacterium extorquens DM4 8194792 YP_003071010.1 CDS METDI5600 NC_012988.1 5567991 5568479 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5567991..5568479) Methylobacterium extorquens DM4 8195052 YP_003071011.1 CDS METDI5602 NC_012988.1 5569030 5570109 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5569030..5570109 Methylobacterium extorquens DM4 8194794 YP_003071012.1 CDS METDI5603 NC_012988.1 5570114 5571067 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5570114..5571067) Methylobacterium extorquens DM4 8194795 YP_003071013.1 CDS MEDTI5956 NC_012988.1 5571164 5571652 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5571164..5571652 Methylobacterium extorquens DM4 8194796 YP_003071014.1 CDS METDI5604 NC_012988.1 5571657 5572070 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mannose-6-phosphate isomerase 5571657..5572070 Methylobacterium extorquens DM4 8190537 YP_003071015.1 CDS METDI5605 NC_012988.1 5572116 5572412 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5572116..5572412 Methylobacterium extorquens DM4 8194797 YP_003071016.1 CDS ibpA NC_012988.1 5572487 5572957 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12055295, 1356969, 20179655, 93015757, 93315143; Product type f : factor; heat shock chaperone complement(5572487..5572957) Methylobacterium extorquens DM4 8194798 YP_003071017.1 CDS METDI5607 NC_012988.1 5573140 5574132 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative lysophospholipase L2 (pldB-like) 5573140..5574132 Methylobacterium extorquens DM4 8195587 YP_003071018.1 CDS METDI5608 NC_012988.1 5574838 5577183 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5574838..5577183 Methylobacterium extorquens DM4 8194799 YP_003071019.1 CDS METDI5609 NC_012988.1 5577350 5578141 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10747806, 8002619, 9401044; Product type pe : putative enzyme; putative inositol mono-phosphatase (suhB-like) complement(5577350..5578141) Methylobacterium extorquens DM4 8194800 YP_003071020.1 CDS METDI5610 NC_012988.1 5578197 5580236 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5578197..5580236) Methylobacterium extorquens DM4 8194801 YP_003071021.1 CDS ybgL NC_012988.1 5580477 5581259 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729609; Product type pe : putative enzyme; hypothetical protein complement(5580477..5581259) Methylobacterium extorquens DM4 8194802 YP_003071022.1 CDS METDI5612 NC_012988.1 5581270 5582568 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(5581270..5582568) Methylobacterium extorquens DM4 8196351 YP_003071023.1 CDS METDI5613 NC_012988.1 5582725 5583228 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16926146, 8012595, 9384377; Product type pf : putative factor; putative General stress protein 26; putative FMN-binding split barrel domain, putative Pyridoxamine 5'-phosphate oxidase domain complement(5582725..5583228) Methylobacterium extorquens DM4 8194803 YP_003071024.1 CDS METDI5614 NC_012988.1 5583396 5583668 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5583396..5583668 Methylobacterium extorquens DM4 8194804 YP_003071025.1 CDS mrp NC_012988.1 5583760 5584887 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15601724, 2259334, 91080852; Product type t : transporter; antiporter inner membrane protein 5583760..5584887 Methylobacterium extorquens DM4 8194805 YP_003071026.1 CDS mobA NC_012988.1 5584941 5585540 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10978347, 12719427, 20568278, 7551035, 80205, 91286221, 92268047, 93368423; Product type pe : putative enzyme; molybdopterin-guanine dinucleotide biosynthesis protein A 5584941..5585540 Methylobacterium extorquens DM4 8195724 YP_003071027.1 CDS gyrA NC_012988.1 5585851 5588586 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9278055; Product type e : enzyme; DNA gyrase, subunit A (type II topoisomerase) 5585851..5588586 Methylobacterium extorquens DM4 8195707 YP_003071028.1 CDS METDI5618 NC_012988.1 5588808 5589632 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative 31 kDa outer-membrane immunogenic protein precursor (omp31) 5588808..5589632 Methylobacterium extorquens DM4 8195543 YP_003071029.1 CDS coaD NC_012988.1 5589775 5590278 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 5589775..5590278 Methylobacterium extorquens DM4 8194806 YP_003071030.1 CDS METDI5620 NC_012988.1 5590321 5590863 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase (rotamase) precursor 5590321..5590863 Methylobacterium extorquens DM4 8195179 YP_003071031.1 CDS METDI5621 NC_012988.1 5590923 5591369 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5590923..5591369 Methylobacterium extorquens DM4 8194807 YP_003071032.1 CDS ppiB NC_012988.1 5591373 5591834 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase B (rotamase B)(PPIase B) 5591373..5591834 Methylobacterium extorquens DM4 8194808 YP_003071033.1 CDS METDI5623 NC_012988.1 5591904 5592308 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) complement(5591904..5592308) Methylobacterium extorquens DM4 8195883 YP_003071034.1 CDS METDI5624 NC_012988.1 5592725 5593462 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15886391; Product type pe : putative enzyme; putative damage-inducible mutagenesis protein (ImuA-like) 5592725..5593462 Methylobacterium extorquens DM4 8194809 YP_003071035.1 CDS METDI5625 NC_012988.1 5593476 5594879 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15886391; Product type pe : putative enzyme; putative damage-inducible mutagenesis protein (ImuB-like) 5593476..5594879 Methylobacterium extorquens DM4 8194810 YP_003071036.1 CDS dnaE NC_012988.1 5594986 5598189 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; error-prone DNA polymerase, DNA polymerase III, alpha subunit 5594986..5598189 Methylobacterium extorquens DM4 8194811 YP_003071037.1 CDS METDI5627 NC_012988.1 5598345 5598557 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5598345..5598557 Methylobacterium extorquens DM4 8195305 YP_003071038.1 CDS METDI5628 NC_012988.1 5598783 5599808 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative patatin-like phospholipase 5598783..5599808 Methylobacterium extorquens DM4 8194812 YP_003071039.1 CDS METDI5629 NC_012988.1 5599973 5600743 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ionic voltage-gated channel protein complement(5599973..5600743) Methylobacterium extorquens DM4 8194813 YP_003071040.1 CDS METDI5630 NC_012988.1 5600771 5600947 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5600771..5600947) Methylobacterium extorquens DM4 8194814 YP_003071041.1 CDS METDI5631 NC_012988.1 5601253 5601564 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5601253..5601564 Methylobacterium extorquens DM4 8194815 YP_003071042.1 CDS fdh1B NC_012988.1 5601628 5603346 D Evidence 1a : Function experimentally demonstrated in the studied strain; Product type e : enzyme; Tungsten-containing formate dehydrogenase beta subunit 5601628..5603346 Methylobacterium extorquens DM4 8194816 YP_003071043.1 CDS fdh1A NC_012988.1 5603399 5606368 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; Tungsten-containing formate dehydrogenase alpha subunit 5603399..5606368 Methylobacterium extorquens DM4 8195361 YP_003071044.1 CDS METDI5635 NC_012988.1 5606640 5607992 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5606640..5607992) Methylobacterium extorquens DM4 8195360 YP_003071045.1 CDS METDI5636 NC_012988.1 5608007 5609005 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5608007..5609005) Methylobacterium extorquens DM4 8194817 YP_003071046.1 CDS METDI5637 NC_012988.1 5609210 5610040 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5609210..5610040 Methylobacterium extorquens DM4 8194818 YP_003071047.1 CDS METDI5638 NC_012988.1 5610178 5611308 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5610178..5611308 Methylobacterium extorquens DM4 8194819 YP_003071048.1 CDS METDI5639 NC_012988.1 5611805 5612257 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5611805..5612257 Methylobacterium extorquens DM4 8194820 YP_003071049.1 CDS METDI5640 NC_012988.1 5612379 5614445 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5612379..5614445) Methylobacterium extorquens DM4 8194821 YP_003071050.1 CDS METDI5641 NC_012988.1 5614442 5616565 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226645, 8226646, 8246891; Product type pt : putative transporter; putative succinoglycan biosynthesis transport protein complement(5614442..5616565) Methylobacterium extorquens DM4 8194822 YP_003071051.1 CDS METDI5642 NC_012988.1 5616744 5618114 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5616744..5618114) Methylobacterium extorquens DM4 8194823 YP_003071052.1 CDS METDI5643 NC_012988.1 5618455 5619399 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5618455..5619399) Methylobacterium extorquens DM4 8194824 YP_003071053.1 CDS METDI5644 NC_012988.1 5619675 5620418 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11669613; Product type e : enzyme; putative 3-oxoacyl-acyl carrier protein reductase (fabG-like) complement(5619675..5620418) Methylobacterium extorquens DM4 8194825 YP_003071054.1 CDS METDI5645 NC_012988.1 5620415 5621776 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative o-succinylbenzoate--CoA ligase complement(5620415..5621776) Methylobacterium extorquens DM4 8194826 YP_003071055.1 CDS METDI5646 NC_012988.1 5621782 5622039 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5621782..5622039) Methylobacterium extorquens DM4 8194827 YP_003071056.1 CDS METDI5647 NC_012988.1 5622080 5622997 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9401025; Product type pe : putative enzyme; putative lipase/esterase (aes-like) complement(5622080..5622997) Methylobacterium extorquens DM4 8194828 YP_003071057.1 CDS METDI5648 NC_012988.1 5623014 5623946 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(5623014..5623946) Methylobacterium extorquens DM4 8194829 YP_003071058.1 CDS acd NC_012988.1 5624120 5625322 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acyl-CoA dehydrogenase complement(5624120..5625322) Methylobacterium extorquens DM4 8194830 YP_003071059.1 CDS METDI5650 NC_012988.1 5625416 5625685 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5625416..5625685) Methylobacterium extorquens DM4 8195048 YP_003071060.1 CDS METDI5651 NC_012988.1 5625820 5626407 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1527048, 7665508, 7665509; Product type pe : putative enzyme; putative monooxygenase, small component; putative flavin:NADH reductase complement(5625820..5626407) Methylobacterium extorquens DM4 8194831 YP_003071061.1 CDS METDI5652 NC_012988.1 5626703 5628406 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; thiamine pyrophosphate protein 5626703..5628406 Methylobacterium extorquens DM4 8194832 YP_003071062.1 CDS METDI5653 NC_012988.1 5628536 5628859 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5628536..5628859 Methylobacterium extorquens DM4 8194833 YP_003071063.1 CDS METDI5654 NC_012988.1 5628904 5629785 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; aminotransferase complement(5628904..5629785) Methylobacterium extorquens DM4 8194834 YP_003071064.1 CDS METDI5655 NC_012988.1 5629973 5630407 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5629973..5630407) Methylobacterium extorquens DM4 8194835 YP_003071065.1 CDS metY-3 NC_012988.1 5630901 5632193 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12951250, 9506902; Product type e : enzyme; trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase) 5630901..5632193 Methylobacterium extorquens DM4 8194836 YP_003071066.1 CDS METDI5657 NC_012988.1 5632227 5633222 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 5632227..5633222 Methylobacterium extorquens DM4 8195690 YP_003071067.1 CDS METDI5658 NC_012988.1 5633234 5635063 D activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; long-chain-acyl-CoA synthetase 5633234..5635063 Methylobacterium extorquens DM4 8194837 YP_003071068.1 CDS METDI5659 NC_012988.1 5635106 5636425 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7476194; Product type pm : putative membrane component; putative EPS I polysaccharide export inner membrane protein (epsE-like) complement(5635106..5636425) Methylobacterium extorquens DM4 8194838 YP_003071069.1 CDS METDI5660 NC_012988.1 5636679 5639015 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5636679..5639015 Methylobacterium extorquens DM4 8194839 YP_003071070.1 CDS METDI5661 NC_012988.1 5639012 5639899 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5639012..5639899 Methylobacterium extorquens DM4 8194840 YP_003071071.1 CDS METDI5662 NC_012988.1 5640083 5642038 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5640083..5642038) Methylobacterium extorquens DM4 8194841 YP_003071072.1 CDS METDI5663 NC_012988.1 5642272 5642613 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative pH adaptation potassium efflux system component (phaG) complement(5642272..5642613) Methylobacterium extorquens DM4 8194842 YP_003071073.1 CDS METDI5664 NC_012988.1 5642610 5642894 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative pH adaptation potassium efflux system component (phaF) complement(5642610..5642894) Methylobacterium extorquens DM4 8194843 YP_003071074.1 CDS METDI5665 NC_012988.1 5642891 5643379 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative pH adaptation potassium efflux system component(phaE) complement(5642891..5643379) Methylobacterium extorquens DM4 8194844 YP_003071075.1 CDS METDI5666 NC_012988.1 5643376 5645046 R subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D complement(5643376..5645046) Methylobacterium extorquens DM4 8194845 YP_003071076.1 CDS METDI5667 NC_012988.1 5645043 5645411 R subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C complement(5645043..5645411) Methylobacterium extorquens DM4 8194846 YP_003071077.1 CDS METDI5668 NC_012988.1 5645411 5648350 R subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; putative monovalent cation/H+ antiporter subunit A complement(5645411..5648350) Methylobacterium extorquens DM4 8194847 YP_003071078.1 CDS METDI5669 NC_012988.1 5648783 5649004 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5648783..5649004) Methylobacterium extorquens DM4 8194848 YP_003071079.1 CDS METDI5670 NC_012988.1 5649466 5650803 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase 5649466..5650803 Methylobacterium extorquens DM4 8194849 YP_003071080.1 CDS METDI5671 NC_012988.1 5650800 5651771 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative UDP-glucose 4-epimerase 5650800..5651771 Methylobacterium extorquens DM4 8194850 YP_003071081.1 CDS fcl NC_012988.1 5651782 5652720 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9473059, 9862812; Product type e : enzyme; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase; GDP-4-dehydro-6-L-deoxygalactose reductase 5651782..5652720 Methylobacterium extorquens DM4 8194851 YP_003071082.1 CDS METDI5673 NC_012988.1 5652704 5653588 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9157246; Product type pe : putative enzyme; putative glycosyl transferase, WecB/TagA/CpsF family 5652704..5653588 Methylobacterium extorquens DM4 8195359 YP_003071083.1 CDS METDI5674 NC_012988.1 5653600 5654772 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10531370; Product type pe : putative enzyme; putative glycosyl transferase 5653600..5654772 Methylobacterium extorquens DM4 8194852 YP_003071084.1 CDS METDI5675 NC_012988.1 5654937 5655104 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5654937..5655104) Methylobacterium extorquens DM4 8194853 YP_003071085.1 CDS METDI5676 NC_012988.1 5655220 5657805 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5655220..5657805) Methylobacterium extorquens DM4 8194854 YP_003071086.1 CDS METDI5677 NC_012988.1 5657802 5661263 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative enterobactin synthase multienzyme complex component, ATP-dependent complement(5657802..5661263) Methylobacterium extorquens DM4 8194855 YP_003071087.1 CDS METDI5678 NC_012988.1 5661592 5662812 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12910271; hypothetical protein complement(5661592..5662812) Methylobacterium extorquens DM4 8194856 YP_003071088.1 CDS METDI5679 NC_012988.1 5662952 5663479 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phosphoglycerate/bisphosphoglycerate mutase complement(5662952..5663479) Methylobacterium extorquens DM4 8194857 YP_003071089.1 CDS METDI5680 NC_012988.1 5663479 5664471 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15292217, 16077126; Product type e : enzyme; NAD(P)-dependent aldo/keto reductase complement(5663479..5664471) Methylobacterium extorquens DM4 8194858 YP_003071090.1 CDS METDI5681 NC_012988.1 5664518 5665369 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; AAA ATPase complement(5664518..5665369) Methylobacterium extorquens DM4 8194859 YP_003071091.1 CDS METDI5682 NC_012988.1 5665465 5666118 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5665465..5666118) Methylobacterium extorquens DM4 8194860 YP_003071092.1 CDS METDI5683 NC_012988.1 5666245 5667483 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5666245..5667483) Methylobacterium extorquens DM4 8194861 YP_003071093.1 CDS METDI5684 NC_012988.1 5667786 5669678 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3301813; Product type pt : putative transporter; putative glutathione-regulated potassium-efflux system protein (kefB/C-like) 5667786..5669678 Methylobacterium extorquens DM4 8194862 YP_003071094.1 CDS murD NC_012988.1 5669713 5671080 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(5669713..5671080) Methylobacterium extorquens DM4 8194863 YP_003071095.1 CDS mraY NC_012988.1 5671105 5672187 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(5671105..5672187) Methylobacterium extorquens DM4 8195739 YP_003071096.1 CDS murF NC_012988.1 5672293 5673756 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11090285; Product type e : enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(5672293..5673756) Methylobacterium extorquens DM4 8195723 YP_003071097.1 CDS murE NC_012988.1 5673753 5675231 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2269304, 7486937; Product type e : enzyme; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(5673753..5675231) Methylobacterium extorquens DM4 8195741 YP_003071098.1 CDS ftsI NC_012988.1 5675291 5677168 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3126399; Product type e : enzyme; Peptidoglycan glycosyltransferase (penicillin-binding protein) complement(5675291..5677168) Methylobacterium extorquens DM4 8195740 YP_003071099.1 CDS METDI5690 NC_012988.1 5677176 5677607 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5677176..5677607) Methylobacterium extorquens DM4 8195452 YP_003071100.1 CDS mraW NC_012988.1 5677604 5678659 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; S-adenosyl-methyltransferase MraW complement(5677604..5678659) Methylobacterium extorquens DM4 8194864 YP_003071101.1 CDS dnlJ NC_012988.1 5679568 5682012 R Evidence 2b : Function of strongly homologous gene; PubMedId : 4377758; Product type e : enzyme; DNA ligase, NAD(+)-dependent complement(5679568..5682012) Methylobacterium extorquens DM4 8196005 YP_003071102.1 CDS METDI5693 NC_012988.1 5682128 5682448 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5682128..5682448 Methylobacterium extorquens DM4 8195312 YP_003071103.1 CDS METDI5694 NC_012988.1 5682619 5682978 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5682619..5682978 Methylobacterium extorquens DM4 8194865 YP_003071104.1 CDS METDI5695 NC_012988.1 5683055 5684068 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Carbohydrate kinase, PfkB 5683055..5684068 Methylobacterium extorquens DM4 8194866 YP_003071105.1 CDS fbp NC_012988.1 5684120 5684542 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1371354; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase (Rotamase) complement(5684120..5684542) Methylobacterium extorquens DM4 8194867 YP_003071106.1 CDS METDI5697 NC_012988.1 5684610 5685077 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5684610..5685077) Methylobacterium extorquens DM4 8195356 YP_003071107.1 CDS METDI5698 NC_012988.1 5685400 5686638 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative L-carnitine dehydratase; putative acyl-CoA-transferase, NAD(P)-binding 5685400..5686638 Methylobacterium extorquens DM4 8194868 YP_003071108.1 CDS croA NC_012988.1 5686662 5687486 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 5686662..5687486 Methylobacterium extorquens DM4 8194869 YP_003071109.1 CDS METDI5700 NC_012988.1 5687518 5688144 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, GntR family complement(5687518..5688144) Methylobacterium extorquens DM4 8195214 YP_003071110.1 CDS METDI5701 NC_012988.1 5688474 5689517 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative L-allo-threonine aldolase (ltaE-like) 5688474..5689517 Methylobacterium extorquens DM4 8194870 YP_003071111.1 CDS METDI5702 NC_012988.1 5689648 5690193 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5689648..5690193) Methylobacterium extorquens DM4 8194871 YP_003071112.1 CDS METDI5703 NC_012988.1 5690277 5691404 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5690277..5691404) Methylobacterium extorquens DM4 8194872 YP_003071113.1 CDS METDI5704 NC_012988.1 5691474 5691845 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5691474..5691845) Methylobacterium extorquens DM4 8194873 YP_003071114.1 CDS METDI5705 NC_012988.1 5691842 5693551 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5691842..5693551) Methylobacterium extorquens DM4 8194874 YP_003071115.1 CDS METDI5706 NC_012988.1 5693569 5694021 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5693569..5694021) Methylobacterium extorquens DM4 8194875 YP_003071116.1 CDS METDI5707 NC_012988.1 5694182 5694475 D Evidence 6 : Doubtful CDS; hypothetical protein 5694182..5694475 Methylobacterium extorquens DM4 8194876 YP_003071117.1 CDS METDI5708 NC_012988.1 5694553 5695716 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative synthetase/amidase complement(5694553..5695716) Methylobacterium extorquens DM4 8194877 YP_003071118.1 CDS METDI5709 NC_012988.1 5695716 5696348 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5695716..5696348) Methylobacterium extorquens DM4 8194878 YP_003071119.1 CDS METDI5710 NC_012988.1 5696353 5696751 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative inner membrane protein complement(5696353..5696751) Methylobacterium extorquens DM4 8194879 YP_003071120.1 CDS pyrG NC_012988.1 5696771 5698399 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(5696771..5698399) Methylobacterium extorquens DM4 8194880 YP_003071121.1 CDS secG NC_012988.1 5698592 5699059 R Evidence 2b : Function of strongly homologous gene; Product type pt : putative transporter; putative secG: preprotein translocase complement(5698592..5699059) Methylobacterium extorquens DM4 8195952 YP_003071122.1 CDS METDI5713 NC_012988.1 5699362 5699643 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5699362..5699643 Methylobacterium extorquens DM4 8196107 YP_003071123.1 CDS METDI5714 NC_012988.1 5699664 5700128 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5699664..5700128 Methylobacterium extorquens DM4 8194881 YP_003071124.1 CDS METDI5715 NC_012988.1 5700153 5700422 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5700153..5700422) Methylobacterium extorquens DM4 8194882 YP_003071125.1 CDS tpiA NC_012988.1 5700663 5701427 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6092857, 8021172, 9202469; Product type e : enzyme; triosephosphate isomerase complement(5700663..5701427) Methylobacterium extorquens DM4 8194883 YP_003071126.1 CDS METDI5717 NC_012988.1 5701662 5703566 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9670013; Product type pe : putative enzyme; putative peptidyl-prolyl cis-trans isomerse D 5701662..5703566 Methylobacterium extorquens DM4 8196207 YP_003071127.1 CDS trpE NC_012988.1 5703576 5705096 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12694904; Product type e : enzyme; anthranilate synthase component I 5703576..5705096 Methylobacterium extorquens DM4 8194884 YP_003071128.1 CDS METDI5719 NC_012988.1 5705158 5706849 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative methyl-accepting chemotaxis sensory transducer precursor; histidine kinase HAMP domain complement(5705158..5706849) Methylobacterium extorquens DM4 8196276 YP_003071129.1 CDS METDI5720 NC_012988.1 5706912 5707088 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5706912..5707088) Methylobacterium extorquens DM4 8194885 YP_003071130.1 CDS trpG NC_012988.1 5707128 5707730 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1896020, 2105306; Product type e : enzyme; aminodeoxychorismate synthase component II, Glutamine amido-transferase 5707128..5707730 Methylobacterium extorquens DM4 8194886 YP_003071131.1 CDS trpD NC_012988.1 5707819 5708832 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 5707819..5708832 Methylobacterium extorquens DM4 8196278 YP_003071132.1 CDS trpC NC_012988.1 5708866 5709723 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12597275, 9061023; Product type e : enzyme; indole-3-glycerol phosphate synthase 5708866..5709723 Methylobacterium extorquens DM4 8196275 YP_003071133.1 CDS moaC NC_012988.1 5709720 5710205 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10903949, 9061023, 93368423; Product type e : enzyme; molybdenum cofactor biosynthesis protein C 5709720..5710205 Methylobacterium extorquens DM4 8196274 YP_003071134.1 CDS METDI5725 NC_012988.1 5710202 5711428 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9515915; Product type pf : putative factor; putative molybdopterin biosynthesis-related protein 5710202..5711428 Methylobacterium extorquens DM4 8195704 YP_003071135.1 CDS METDI5726 NC_012988.1 5711519 5711848 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5711519..5711848 Methylobacterium extorquens DM4 8194887 YP_003071136.1 CDS METDI5727 NC_012988.1 5711859 5712152 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator, XRE family 5711859..5712152 Methylobacterium extorquens DM4 8194888 YP_003071137.1 CDS fabZ NC_012988.1 5712324 5712785 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 5712324..5712785 Methylobacterium extorquens DM4 8194889 YP_003071138.1 CDS lpxA NC_012988.1 5712791 5713597 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 5712791..5713597 Methylobacterium extorquens DM4 8195350 YP_003071139.1 CDS METDI5730 NC_012988.1 5713609 5714457 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5713609..5714457 Methylobacterium extorquens DM4 8195646 YP_003071140.1 CDS lpxB NC_012988.1 5714454 5715614 D Evidence 2b : Function of strongly homologous gene; PubMedId : 3277952, 8917090; Product type e : enzyme; Lipid-A-disaccharide synthase 5714454..5715614 Methylobacterium extorquens DM4 8194890 YP_003071141.1 CDS METDI5732 NC_012988.1 5715611 5716090 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5715611..5716090 Methylobacterium extorquens DM4 8195647 YP_003071142.1 CDS gltA NC_012988.1 5716236 5717525 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1939121; Product type e : enzyme; citrate synthase complement(5716236..5717525) Methylobacterium extorquens DM4 8194891 YP_003071143.1 CDS gltX NC_012988.1 5718001 5719425 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glutamate tRNA synthetase, catalytic subunit complement(5718001..5719425) Methylobacterium extorquens DM4 8195511 YP_003071144.1 CDS METDI5735 NC_012988.1 5719593 5721851 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5719593..5721851 Methylobacterium extorquens DM4 8195517 YP_003071145.1 CDS lexA NC_012988.1 5721845 5722621 R Represses a number of genes involved in the response to DNA damage; LexA repressor complement(5721845..5722621) Methylobacterium extorquens DM4 8194892 YP_003071146.1 CDS METDI5737 NC_012988.1 5722949 5723743 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5722949..5723743 Methylobacterium extorquens DM4 8195633 YP_003071147.1 CDS kgtP NC_012988.1 5724047 5725402 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2053984, 8419306; Product type t : transporter; alpha-ketoglutarate permease (MFS transporter membrane protein) 5724047..5725402 Methylobacterium extorquens DM4 8194893 YP_003071148.1 CDS METDI5740 NC_012988.1 5725515 5726339 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5725515..5726339) Methylobacterium extorquens DM4 8195624 YP_003071149.1 CDS ttuC NC_012988.1 5726353 5727432 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12356321, 2184888, 8457548; Product type e : enzyme; Tartrate dehydrogenase/decarboxylase (TDH) (D-malate dehydrogenase [decarboxylating]) complement(5726353..5727432) Methylobacterium extorquens DM4 8194894 YP_003071150.1 CDS METDI5742 NC_012988.1 5727572 5728033 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5727572..5728033) Methylobacterium extorquens DM4 8196288 YP_003071151.1 CDS METDI5743 NC_012988.1 5728143 5729021 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, aldo/keto reductase family complement(5728143..5729021) Methylobacterium extorquens DM4 8194895 YP_003071152.1 CDS METDI5744 NC_012988.1 5729103 5729828 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5729103..5729828) Methylobacterium extorquens DM4 8194896 YP_003071153.1 CDS METDI5745 NC_012988.1 5730024 5731955 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5730024..5731955) Methylobacterium extorquens DM4 8194897 YP_003071154.1 CDS depP NC_012988.1 5732398 5733909 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; periplasmic serine protease (DegP) complement(5732398..5733909) Methylobacterium extorquens DM4 8194898 YP_003071155.1 CDS METDI5747 NC_012988.1 5734023 5734775 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5734023..5734775) Methylobacterium extorquens DM4 8195291 YP_003071156.1 CDS valS NC_012988.1 5734772 5737621 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 182209, 8611551; Product type e : enzyme; valine tRNA synthetase complement(5734772..5737621) Methylobacterium extorquens DM4 8194899 YP_003071157.1 CDS METDI5749 NC_012988.1 5737936 5738484 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5737936..5738484) Methylobacterium extorquens DM4 8196333 YP_003071158.1 CDS METDI5750 NC_012988.1 5738658 5740169 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative type I secretion outer membrane protein, TolC precursor complement(5738658..5740169) Methylobacterium extorquens DM4 8194900 YP_003071159.1 CDS METDI5751 NC_012988.1 5740691 5741341 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein complement(5740691..5741341) Methylobacterium extorquens DM4 8194901 YP_003071160.1 CDS METDI5753 NC_012988.1 5743089 5743391 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5743089..5743391 Methylobacterium extorquens DM4 8196251 YP_003071161.1 CDS METDI5756 NC_012988.1 5744973 5745188 D Evidence 6 : Doubtful CDS; hypothetical protein 5744973..5745188 Methylobacterium extorquens DM4 8194904 YP_003071162.1 CDS METDI5757 NC_012988.1 5745157 5745519 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5745157..5745519) Methylobacterium extorquens DM4 8194905 YP_003071163.1 CDS METDI5758 NC_012988.1 5746347 5746721 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5746347..5746721) Methylobacterium extorquens DM4 8194906 YP_003071164.1 CDS METDI5759 NC_012988.1 5746897 5747172 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5746897..5747172) Methylobacterium extorquens DM4 8194907 YP_003071165.1 CDS METDI5760 NC_012988.1 5747200 5747454 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5747200..5747454) Methylobacterium extorquens DM4 8194908 YP_003071166.1 CDS METDI5761 NC_012988.1 5747884 5748780 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5747884..5748780) Methylobacterium extorquens DM4 8194909 YP_003071167.1 CDS METDI5762 NC_012988.1 5749373 5749735 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5749373..5749735 Methylobacterium extorquens DM4 8194910 YP_003071168.1 CDS METDI5763 NC_012988.1 5749971 5750165 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5749971..5750165 Methylobacterium extorquens DM4 8194911 YP_003071169.1 CDS METDI5764 NC_012988.1 5751037 5751243 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5751037..5751243 Methylobacterium extorquens DM4 8194912 YP_003071170.1 CDS METDI5765 NC_012988.1 5751284 5751559 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5751284..5751559) Methylobacterium extorquens DM4 8194913 YP_003071171.1 CDS pstS NC_012988.1 5751979 5753019 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; phosphate ABC transporter, periplasmic phosphate binding protein 5751979..5753019 Methylobacterium extorquens DM4 8194914 YP_003071172.1 CDS pstC NC_012988.1 5753134 5754108 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; phosphate ABC transporter, permease 5753134..5754108 Methylobacterium extorquens DM4 8195913 YP_003071173.1 CDS pstA NC_012988.1 5754153 5755046 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; phosphate ABC transporter, permease 5754153..5755046 Methylobacterium extorquens DM4 8195912 YP_003071174.1 CDS pstB NC_012988.1 5755088 5755903 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; phosphate ABC transporter, ATPase 5755088..5755903 Methylobacterium extorquens DM4 8195910 YP_003071175.1 CDS phoU NC_012988.1 5756035 5756748 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; phosphate transport system regulatory protein PhoU 5756035..5756748 Methylobacterium extorquens DM4 8195911 YP_003071176.1 CDS phoB NC_012988.1 5756831 5757535 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 90133909, 91100346; Product type r : regulator; phosphate regulon transcriptional regulatory protein PhoB 5756831..5757535 Methylobacterium extorquens DM4 8195863 YP_003071177.1 CDS METDI5772 NC_012988.1 5757741 5758280 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5757741..5758280) Methylobacterium extorquens DM4 8195862 YP_003071178.1 CDS METDI5773 NC_012988.1 5758792 5759658 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5758792..5759658 Methylobacterium extorquens DM4 8194915 YP_003071179.1 CDS dinB NC_012988.1 5759669 5760916 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(5759669..5760916) Methylobacterium extorquens DM4 8194916 YP_003071180.1 CDS cobK NC_012988.1 5761003 5761824 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1732193, 2211521; Product type e : enzyme; Precorrin-6A reductase (Precorrin-6X reductase) 5761003..5761824 Methylobacterium extorquens DM4 8195295 YP_003071181.1 CDS cobQ1 NC_012988.1 5761895 5763352 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11743193, 11743194; Product type e : enzyme; cobyric acid synthase 5761895..5763352 Methylobacterium extorquens DM4 8195191 YP_003071182.1 CDS cobD NC_012988.1 5763461 5764462 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2211520; Product type e : enzyme; Cobalamin biosynthesis protein cobD complement(5763461..5764462) Methylobacterium extorquens DM4 8195195 YP_003071183.1 CDS cobC NC_012988.1 5764489 5765484 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2211520; Product type e : enzyme; Threonine-phosphate decarboxylase (L-threonine-O-3-phosphate decarboxylase) 5764489..5765484 Methylobacterium extorquens DM4 8195185 YP_003071184.1 CDS METDI5779 NC_012988.1 5765477 5766661 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Sugar efflux transporter B complement(5765477..5766661) Methylobacterium extorquens DM4 8195184 YP_003071185.1 CDS METDI5780 NC_012988.1 5767068 5767271 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5767068..5767271 Methylobacterium extorquens DM4 8194917 YP_003071186.1 CDS matA NC_012988.1 5767473 5768882 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9826185; Product type e : enzyme; malonyl-CoA decarboxylase 5767473..5768882 Methylobacterium extorquens DM4 8194918 YP_003071187.1 CDS METDI5782 NC_012988.1 5769019 5769375 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11988534; hypothetical protein 5769019..5769375 Methylobacterium extorquens DM4 8195662 YP_003071188.1 CDS hbd NC_012988.1 5769529 5770314 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 11208803, 16926146; Product type e : enzyme; D-beta-hydroxybutyrate dehydrogenase complement(5769529..5770314) Methylobacterium extorquens DM4 8194919 YP_003071189.1 CDS accA NC_012988.1 5770519 5771481 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 5770519..5771481 Methylobacterium extorquens DM4 8195545 YP_003071190.1 CDS METDI5785 NC_012988.1 5771478 5772191 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5771478..5772191 Methylobacterium extorquens DM4 8195044 YP_003071191.1 CDS METDI5786 NC_012988.1 5772339 5773727 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5772339..5773727 Methylobacterium extorquens DM4 8194920 YP_003071192.1 CDS rplS NC_012988.1 5773926 5774330 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 5773926..5774330 Methylobacterium extorquens DM4 8194921 YP_003071193.1 CDS METDI5788 NC_012988.1 5774573 5774932 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleotidyltransferase domain 5774573..5774932 Methylobacterium extorquens DM4 8196028 YP_003071194.1 CDS METDI5789 NC_012988.1 5774998 5775333 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5774998..5775333 Methylobacterium extorquens DM4 8194922 YP_003071195.1 CDS METDI5790 NC_012988.1 5775364 5776560 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-bound lytic murein transglycosylase complement(5775364..5776560) Methylobacterium extorquens DM4 8194923 YP_003071196.1 CDS rpsD NC_012988.1 5777013 5777630 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 5777013..5777630 Methylobacterium extorquens DM4 8194924 YP_003071197.1 CDS 2-npdl NC_012988.1 5777759 5778811 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7813473; Product type e : enzyme; 2-nitropropane dioxygenase, (nitroalkane oxidase) (2-NPD) complement(5777759..5778811) Methylobacterium extorquens DM4 8196055 YP_003071198.1 CDS pssA NC_012988.1 5778913 5779755 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14996797; Product type e : enzyme; phosphatidylserine synthase (pssA-like) complement(5778913..5779755) Methylobacterium extorquens DM4 8195041 YP_003071199.1 CDS psd NC_012988.1 5779830 5780540 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; phosphatidylserine decarboxylase (psd-like) complement(5779830..5780540) Methylobacterium extorquens DM4 8195909 YP_003071200.1 CDS METDI5795 NC_012988.1 5780616 5782607 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, fused ATPase and permease domains complement(5780616..5782607) Methylobacterium extorquens DM4 8195908 YP_003071201.1 CDS METDI5796 NC_012988.1 5782666 5784201 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative peptidoglycan-binding precursor LysM complement(5782666..5784201) Methylobacterium extorquens DM4 8194925 YP_003071202.1 CDS METDI5797 NC_012988.1 5784418 5785020 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5784418..5785020 Methylobacterium extorquens DM4 8194926 YP_003071203.1 CDS METDI5798 NC_012988.1 5785020 5785811 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5785020..5785811 Methylobacterium extorquens DM4 8194927 YP_003071204.1 CDS cysS NC_012988.1 5785866 5787254 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(5785866..5787254) Methylobacterium extorquens DM4 8194928 YP_003071205.1 CDS METDI5800 NC_012988.1 5787583 5787906 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5787583..5787906 Methylobacterium extorquens DM4 8195261 YP_003071206.1 CDS METDI5801 NC_012988.1 5787920 5788474 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5787920..5788474) Methylobacterium extorquens DM4 8194929 YP_003071207.1 CDS METDI5802 NC_012988.1 5788548 5789648 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5788548..5789648 Methylobacterium extorquens DM4 8194930 YP_003071208.1 CDS METDI5803 NC_012988.1 5789812 5791965 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5789812..5791965 Methylobacterium extorquens DM4 8194931 YP_003071209.1 CDS ynfM NC_012988.1 5792139 5793353 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; Inner membrane transport protein ynfM 5792139..5793353 Methylobacterium extorquens DM4 8194932 YP_003071210.1 CDS METDI5805 NC_012988.1 5793440 5793931 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 3-demethylubiquinone-9 3-methyltransferase 5793440..5793931 Methylobacterium extorquens DM4 8196376 YP_003071211.1 CDS yafE NC_012988.1 5793928 5794707 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase 5793928..5794707 Methylobacterium extorquens DM4 8194933 YP_003071212.1 CDS gltX NC_012988.1 5794704 5796053 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(5794704..5796053) Methylobacterium extorquens DM4 8196347 YP_003071213.1 CDS METDI5808 NC_012988.1 5796110 5797189 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative efflux pump component complement(5796110..5797189) Methylobacterium extorquens DM4 8195518 YP_003071214.1 CDS METDI5809 NC_012988.1 5797186 5797380 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5797186..5797380) Methylobacterium extorquens DM4 8194934 YP_003071215.1 CDS METDI5810 NC_012988.1 5797389 5799425 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative membrane protein; putative efflux transporter protein complement(5797389..5799425) Methylobacterium extorquens DM4 8194935 YP_003071216.1 CDS METDI5811 NC_012988.1 5799422 5799856 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5799422..5799856) Methylobacterium extorquens DM4 8194936 YP_003071217.1 CDS METDI5812 NC_012988.1 5800019 5800300 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5800019..5800300) Methylobacterium extorquens DM4 8194937 YP_003071218.1 CDS METDI5813 NC_012988.1 5800627 5801295 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase 5800627..5801295 Methylobacterium extorquens DM4 8194938 YP_003071219.1 CDS tolB NC_012988.1 5802195 5803535 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10673426, 10735848, 8955385; Product type t : transporter; protein tolB precursor complement(5802195..5803535) Methylobacterium extorquens DM4 8194939 YP_003071220.1 CDS tolA NC_012988.1 5803614 5805029 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10404600, 2068069, 2687247, 8905232, 8978668; Product type m : membrane component; TolA-TolQ-TolR complex membrane anchor protein complement(5803614..5805029) Methylobacterium extorquens DM4 8196204 YP_003071221.1 CDS METDI5817 NC_012988.1 5805044 5805493 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1644779, 2670903, 88273230, 93302502, 8063379; Product type m : membrane component; biopolymer transport protein ExbD/TolR complement(5805044..5805493) Methylobacterium extorquens DM4 8196203 YP_003071222.1 CDS tolQ NC_012988.1 5805543 5806259 R Evidence 2b : Function of strongly homologous gene; Product type m : membrane component; membrane spanning protein in TolA-TolQ-TolR complex complement(5805543..5806259) Methylobacterium extorquens DM4 8194940 YP_003071223.1 CDS METDI5819 NC_012988.1 5806699 5807949 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12029363, 7708770; hypothetical protein 5806699..5807949 Methylobacterium extorquens DM4 8196205 YP_003071224.1 CDS ybgC NC_012988.1 5807936 5808373 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10493123, 11959124, 15808744, 16294310, 3294803; Product type e : enzyme; acyl-CoA thioesterase complement(5807936..5808373) Methylobacterium extorquens DM4 8194941 YP_003071225.1 CDS METDI5821 NC_012988.1 5808538 5809254 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5808538..5809254) Methylobacterium extorquens DM4 8196350 YP_003071226.1 CDS ruvB NC_012988.1 5809693 5810763 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(5809693..5810763) Methylobacterium extorquens DM4 8194942 YP_003071227.1 CDS METDI5824 NC_012988.1 5811219 5812979 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidoglycan-binding protein (N-terminal domain) 5811219..5812979 Methylobacterium extorquens DM4 8196096 YP_003071228.1 CDS METDI5825 NC_012988.1 5813125 5813652 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10966408, 16926146; Product type pf : putative factor; Dps protein family starvation-inducible DNA-binding protein 5813125..5813652 Methylobacterium extorquens DM4 8194943 YP_003071229.1 CDS METDI5826 NC_012988.1 5813738 5816440 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5813738..5816440) Methylobacterium extorquens DM4 8194944 YP_003071230.1 CDS fucA NC_012988.1 5816785 5817435 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10821675, 11054289, 15299567; Product type e : enzyme; L-fuculose-1-phosphate aldolase 5816785..5817435 Methylobacterium extorquens DM4 8194945 YP_003071231.1 CDS METDI5828 NC_012988.1 5817614 5817811 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5817614..5817811) Methylobacterium extorquens DM4 8195458 YP_003071232.1 CDS METDI5829 NC_012988.1 5818030 5818557 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10656595, 11481430, 7756693; Product type r : regulator; transcriptional regulator (RosR/MucR family) 5818030..5818557 Methylobacterium extorquens DM4 8194946 YP_003071233.1 CDS METDI5831 NC_012988.1 5818777 5819559 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5818777..5819559 Methylobacterium extorquens DM4 8194947 YP_003071234.1 CDS METDI5832 NC_012988.1 5819562 5820863 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein complement(5819562..5820863) Methylobacterium extorquens DM4 8194948 YP_003071235.1 CDS pbpC NC_012988.1 5821342 5823525 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8335642; Product type e : enzyme; penicillin-binding protein 5821342..5823525 Methylobacterium extorquens DM4 8194949 YP_003071236.1 CDS METDI5834 NC_012988.1 5823649 5824887 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7750735; Product type pe : putative enzyme; putative transmembrane adenylate/guanylate cyclase 5823649..5824887 Methylobacterium extorquens DM4 8195831 YP_003071237.1 CDS METDI5835 NC_012988.1 5824906 5825304 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Glutathione S-transferase related protein, MAPEG superfamily complement(5824906..5825304) Methylobacterium extorquens DM4 8194950 YP_003071238.1 CDS METDI5836 NC_012988.1 5825601 5826506 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cobyrinic acid a,c-diamide synthase 5825601..5826506 Methylobacterium extorquens DM4 8194951 YP_003071239.1 CDS METDI5837 NC_012988.1 5826496 5827020 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5826496..5827020 Methylobacterium extorquens DM4 8194952 YP_003071240.1 CDS METDI5838 NC_012988.1 5827045 5827389 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5827045..5827389) Methylobacterium extorquens DM4 8194953 YP_003071241.1 CDS groL NC_012988.1 5827525 5829165 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; 60 kDa chaperonin (protein Cpn60, groEL protein) complement(5827525..5829165) Methylobacterium extorquens DM4 8194954 YP_003071242.1 CDS groES NC_012988.1 5829258 5829548 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(5829258..5829548) Methylobacterium extorquens DM4 8195533 YP_003071243.1 CDS METDI5841 NC_012988.1 5829763 5830767 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative magnesium/cobalt transport protein 5829763..5830767 Methylobacterium extorquens DM4 8195535 YP_003071244.1 CDS METDI5842 NC_012988.1 5830810 5831451 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative multiple antibiotic resistance protein, MarC family transport protein complement(5830810..5831451) Methylobacterium extorquens DM4 8194955 YP_003071245.1 CDS METDI5843 NC_012988.1 5831628 5833088 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5831628..5833088 Methylobacterium extorquens DM4 8194956 YP_003071246.1 CDS METDI5844 NC_012988.1 5833220 5834410 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8606183, 96178972; Product type pe : putative enzyme; putative glycolate oxidase subunit GlcE 5833220..5834410 Methylobacterium extorquens DM4 8194957 YP_003071247.1 CDS pitA NC_012988.1 5834424 5836064 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; low-affinity phosphate transport protein (PiT family) complement(5834424..5836064) Methylobacterium extorquens DM4 8194958 YP_003071248.1 CDS METDI5846 NC_012988.1 5836391 5836600 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5836391..5836600 Methylobacterium extorquens DM4 8195866 YP_003071249.1 CDS METDI5847 NC_012988.1 5836700 5836885 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5836700..5836885 Methylobacterium extorquens DM4 8194959 YP_003071250.1 CDS METDI5848 NC_012988.1 5836894 5837196 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5836894..5837196 Methylobacterium extorquens DM4 8194960 YP_003071251.1 CDS glpD NC_012988.1 5837193 5838710 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 5837193..5838710 Methylobacterium extorquens DM4 8194961 YP_003071252.1 CDS algA NC_012988.1 5838698 5840131 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1846611; Product type e : enzyme; Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase complement(5838698..5840131) Methylobacterium extorquens DM4 8195507 YP_003071253.1 CDS mcmA NC_012988.1 5840325 5842490 R MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase complement(5840325..5842490) Methylobacterium extorquens DM4 8195069 YP_003071254.1 CDS METDI5852 NC_012988.1 5842596 5843096 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5842596..5843096) Methylobacterium extorquens DM4 8195668 YP_003071255.1 CDS METDI5853 NC_012988.1 5843212 5844141 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5843212..5844141 Methylobacterium extorquens DM4 8194962 YP_003071256.1 CDS METDI5854 NC_012988.1 5844134 5844349 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5844134..5844349) Methylobacterium extorquens DM4 8194963 YP_003071257.1 CDS METDI5855 NC_012988.1 5844867 5846012 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; serine protease 5844867..5846012 Methylobacterium extorquens DM4 8194964 YP_003071258.1 CDS METDI5856 NC_012988.1 5846082 5846777 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5846082..5846777 Methylobacterium extorquens DM4 8194965 YP_003071259.1 CDS METDI5857 NC_012988.1 5847007 5848491 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative D-alanyl-D-alanine carboxypeptidase complement(5847007..5848491) Methylobacterium extorquens DM4 8194966 YP_003071260.1 CDS clpS NC_012988.1 5848982 5849320 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11931773, 12576022; Product type r : regulator; ATP-dependent Clp protease adaptor protein clpS 5848982..5849320 Methylobacterium extorquens DM4 8194967 YP_003071261.1 CDS clpA NC_012988.1 5849343 5851826 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12205096, 122351, 21243159, 21369885, 2185473, 90243657, 9573050, 9575205; Product type e : enzyme; ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity 5849343..5851826 Methylobacterium extorquens DM4 8195173 YP_003071262.1 CDS METDI5860 NC_012988.1 5851962 5852234 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5851962..5852234 Methylobacterium extorquens DM4 8195168 YP_003071263.1 CDS hemA NC_012988.1 5852247 5853464 R catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase complement(5852247..5853464) Methylobacterium extorquens DM4 8194968 YP_003071264.1 CDS METDI5862 NC_012988.1 5853520 5854329 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5853520..5854329) Methylobacterium extorquens DM4 8195548 YP_003071265.1 CDS acsF NC_012988.1 5854331 5855425 R oxidative; catalyzes the formation of divinylprotochlorophyllide from magnesium-protoporphyrin IX 13-monomethyl ester in isocyclic ring formation in chlorophyll biosynthesis; magnesium-protoporphyrin IX monomethyl ester cyclase complement(5854331..5855425) Methylobacterium extorquens DM4 8194969 YP_003071266.1 CDS METDI5864 NC_012988.1 5855422 5855718 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5855422..5855718) Methylobacterium extorquens DM4 8195058 YP_003071267.1 CDS METDI5865 NC_012988.1 5855748 5856218 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5855748..5856218) Methylobacterium extorquens DM4 8194970 YP_003071268.1 CDS METDI5866 NC_012988.1 5856234 5856938 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5856234..5856938) Methylobacterium extorquens DM4 8194971 YP_003071269.1 CDS puhA NC_012988.1 5856950 5857723 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; photosynthetic reaction center subunit H complement(5856950..5857723) Methylobacterium extorquens DM4 8194972 YP_003071270.1 CDS lhaA NC_012988.1 5857738 5859183 R Evidence 2b : Function of strongly homologous gene; Product type t : transporter; photosynthetic complex (LH1) assembly protein LhaA, Major Facilitator Superfamily (MFS) transporter complement(5857738..5859183) Methylobacterium extorquens DM4 8195928 YP_003071271.1 CDS bchM NC_012988.1 5859180 5859911 R catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine; Mg-protoporphyrin IX methyl transferase complement(5859180..5859911) Methylobacterium extorquens DM4 8195635 YP_003071272.1 CDS chlL NC_012988.1 5859911 5860804 R light-independent; with chlN(bchN) and chlB(bchB) reduces ring D of protochlorophyllide to form chlorophyllide a in chlorophyll/bacteriochlorophyll production; protochlorophyllide reductase iron-sulfur ATP-binding protein complement(5859911..5860804) Methylobacterium extorquens DM4 8195134 YP_003071273.1 CDS bchH NC_012988.1 5860801 5864517 R involved in chelation of magnesium into protoporphyrin IX; involved in bacteriochlorophyll biosynthesis; the enzyme from Rhodobacter capsulatus contains an Fe-S cluster; part of a complex with BchI, BchD, and BchH; magnesium chelatase subunit H complement(5860801..5864517) Methylobacterium extorquens DM4 8195133 YP_003071274.1 CDS bchB NC_012988.1 5864492 5866087 R light-independent reduction of protochlorophyllide to form chlorophyllide a; light-independent protochlorophyllide reductase subunit B complement(5864492..5866087) Methylobacterium extorquens DM4 8195131 YP_003071275.1 CDS bchN NC_012988.1 5866093 5867361 R light-independent reduction of protochlorophyllide to form chlorophyllide a; light-independent protochlorophyllide reductase subunit N complement(5866093..5867361) Methylobacterium extorquens DM4 8195125 YP_003071276.1 CDS bchF NC_012988.1 5867358 5867861 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8385667; Product type e : enzyme; 2-vinyl bacteriochlorophyllide hydratase complement(5867358..5867861) Methylobacterium extorquens DM4 8195135 YP_003071277.1 CDS METDI5875 NC_012988.1 5868118 5869005 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5868118..5869005 Methylobacterium extorquens DM4 8195129 YP_003071278.1 CDS ppsR NC_012988.1 5869033 5870493 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator PpsR-CrtJ; Fis family 5869033..5870493 Methylobacterium extorquens DM4 8194973 YP_003071279.1 CDS bchG NC_012988.1 5870616 5871503 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; bacteriochlorophyll/chlorophyll a synthase 5870616..5871503 Methylobacterium extorquens DM4 8195886 YP_003071280.1 CDS pucC NC_012988.1 5871500 5872879 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; light harvesting pigment Major Facilitator Family (MFS) transporter, (Bch2-like) 5871500..5872879 Methylobacterium extorquens DM4 8195130 YP_003071281.1 CDS bchP NC_012988.1 5872884 5874077 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; geranylgeranyl reductase 5872884..5874077 Methylobacterium extorquens DM4 8195922 YP_003071282.1 CDS METDI5880 NC_012988.1 5874074 5874583 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11097914, 7673149; Product type m : membrane component; tryptophan-rich sensory membrane protein precursor (CrtK homolog); putative regulatory receptor protein 5874074..5874583 Methylobacterium extorquens DM4 8195136 YP_003071283.1 CDS METDI5881 NC_012988.1 5874587 5874952 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5874587..5874952 Methylobacterium extorquens DM4 8194974 YP_003071284.1 CDS METDI5882 NC_012988.1 5874996 5876591 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9352901; Product type pc : putative carrier; putative cytochrome c, putative exported protein 5874996..5876591 Methylobacterium extorquens DM4 8194975 YP_003071285.1 CDS gnd NC_012988.1 5876766 5877758 D similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase-like protein 5876766..5877758 Methylobacterium extorquens DM4 8194976 YP_003071286.1 CDS pgl NC_012988.1 5877755 5878486 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10518023; Product type e : enzyme; 6-phosphogluconolactonase 5877755..5878486 Methylobacterium extorquens DM4 8195524 YP_003071287.1 CDS METDI5885 NC_012988.1 5878599 5879165 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5878599..5879165 Methylobacterium extorquens DM4 8195850 YP_003071288.1 CDS METDI5886 NC_012988.1 5879278 5881050 R responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABC transporter complement(5879278..5881050) Methylobacterium extorquens DM4 8194977 YP_003071289.1 CDS METDI5887 NC_012988.1 5881321 5882094 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f : factor; putative chemotaxis protein (flagellar motor component) 5881321..5882094 Methylobacterium extorquens DM4 8194978 YP_003071290.1 CDS METDI5888 NC_012988.1 5882109 5882942 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative chemotaxis protein MotB 5882109..5882942 Methylobacterium extorquens DM4 8194979 YP_003071291.1 CDS METDI5889 NC_012988.1 5882964 5883392 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5882964..5883392) Methylobacterium extorquens DM4 8194980 YP_003071292.1 CDS METDI5890 NC_012988.1 5883595 5886288 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5883595..5886288) Methylobacterium extorquens DM4 8194981 YP_003071293.1 CDS METDI5891 NC_012988.1 5887036 5887584 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative endonuclease 5887036..5887584 Methylobacterium extorquens DM4 8194982 YP_003071294.1 CDS METDI5892 NC_012988.1 5887592 5887849 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5887592..5887849) Methylobacterium extorquens DM4 8194983 YP_003071295.1 CDS METDI5893 NC_012988.1 5887876 5888775 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8751924; Product type pm : putative membrane component; putative outer-membrane immunogenic protein precursor complement(5887876..5888775) Methylobacterium extorquens DM4 8194984 YP_003071296.1 CDS METDI5894 NC_012988.1 5889013 5889870 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5889013..5889870) Methylobacterium extorquens DM4 8194985 YP_003071297.1 CDS METDI5895 NC_012988.1 5890051 5890914 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5890051..5890914) Methylobacterium extorquens DM4 8194986 YP_003071298.1 CDS glmM NC_012988.1 5891192 5892532 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(5891192..5892532) Methylobacterium extorquens DM4 8194987 YP_003071299.1 CDS METDI5897 NC_012988.1 5892718 5893467 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative inner membrane protein complement(5892718..5893467) Methylobacterium extorquens DM4 8195494 YP_003071300.1 CDS ftsH NC_012988.1 5893583 5895511 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; cell division protease; ATP-dependent metalloprotease complement(5893583..5895511) Methylobacterium extorquens DM4 8194988 YP_003071301.1 CDS tilS NC_012988.1 5895649 5896677 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10572147; Product type e : enzyme; tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase, tRNA(Ile)-2-lysyl-cytidine synthase); YaeN protein complement(5895649..5896677) Methylobacterium extorquens DM4 8195451 YP_003071302.1 CDS METDI5900 NC_012988.1 5896674 5897699 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5896674..5897699) Methylobacterium extorquens DM4 8196198 YP_003071303.1 CDS omp16 NC_012988.1 5897873 5898385 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10456959; Product type m : membrane component; Outer membrane lipoprotein omp16 precursor complement(5897873..5898385) Methylobacterium extorquens DM4 8194989 YP_003071304.1 CDS METDI5902 NC_012988.1 5898770 5899123 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5898770..5899123) Methylobacterium extorquens DM4 8195805 YP_003071305.1 CDS METDI5903 NC_012988.1 5899226 5899624 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative reponse regulator (cheY-like protein) 5899226..5899624 Methylobacterium extorquens DM4 8194990 YP_003071306.1 CDS METDI5904 NC_012988.1 5899713 5900735 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5899713..5900735) Methylobacterium extorquens DM4 8194991 YP_003071307.1 CDS METDI5905 NC_012988.1 5900783 5901844 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5900783..5901844 Methylobacterium extorquens DM4 8194992 YP_003071308.1 CDS hemC NC_012988.1 5901991 5902875 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11872720, 7784514; Product type e : enzyme; Porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) complement(5901991..5902875) Methylobacterium extorquens DM4 8194993 YP_003071309.1 CDS METDI5907 NC_012988.1 5903653 5905269 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16169924; Product type pe : putative enzyme; putative gamma-glutamyltranspeptidase complement(5903653..5905269) Methylobacterium extorquens DM4 8196238 YP_003071310.1 CDS METDI5908 NC_012988.1 5905443 5906381 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5905443..5906381) Methylobacterium extorquens DM4 8194994 YP_003071311.1 CDS METDI5909 NC_012988.1 5906378 5908849 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, putative membrane protein precursor with two ATP-binding domains complement(5906378..5908849) Methylobacterium extorquens DM4 8194995 YP_003071312.1 CDS METDI5910 NC_012988.1 5908852 5909721 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, permease precursor complement(5908852..5909721) Methylobacterium extorquens DM4 8194996 YP_003071313.1 CDS METDI5911 NC_012988.1 5909768 5910958 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter, periplasmic protein complement(5909768..5910958) Methylobacterium extorquens DM4 8194997 YP_003071314.1 CDS METDI5912 NC_012988.1 5911169 5911579 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5911169..5911579 Methylobacterium extorquens DM4 8194998 YP_003071315.1 CDS METDI5913 NC_012988.1 5911584 5912183 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Transcriptional regulator, GntR family complement(5911584..5912183) Methylobacterium extorquens DM4 8194999 YP_003071316.1 CDS METDI5914 NC_012988.1 5912718 5913173 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5912718..5913173) Methylobacterium extorquens DM4 8195000 YP_003071317.1 CDS METDI5915 NC_012988.1 5914123 5914503 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5914123..5914503 Methylobacterium extorquens DM4 8195001 YP_003071318.1 CDS METDI5916 NC_012988.1 5914578 5915594 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5914578..5915594) Methylobacterium extorquens DM4 8195002 YP_003071319.1 CDS METDI5917 NC_012988.1 5915719 5916048 R Evidence 5 : No homology to any previously reported sequences; PubMedId : 8102363; hypothetical protein complement(5915719..5916048) Methylobacterium extorquens DM4 8195003 YP_003071320.1 CDS METDI5918 NC_012988.1 5915990 5917324 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative tartrate transporter ttuB complement(5915990..5917324) Methylobacterium extorquens DM4 8195004 YP_003071321.1 CDS METDI5919 NC_012988.1 5917606 5918109 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15188393, 16926146; hypothetical protein 5917606..5918109 Methylobacterium extorquens DM4 8195005 YP_003071322.1 CDS METDI5920 NC_012988.1 5918298 5919791 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5918298..5919791 Methylobacterium extorquens DM4 8195006 YP_003071323.1 CDS METDI5921 NC_012988.1 5919949 5920302 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5919949..5920302 Methylobacterium extorquens DM4 8195007 YP_003071324.1 CDS ilvI NC_012988.1 5920456 5922231 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3891724, 6308579, 89155476, 92380929, 9298646; Product type e : enzyme; acetolactate synthase III, large subunit 5920456..5922231 Methylobacterium extorquens DM4 8195008 YP_003071325.1 CDS METDI5923 NC_012988.1 5922292 5923203 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5922292..5923203) Methylobacterium extorquens DM4 8195596 YP_003071326.1 CDS ilvH NC_012988.1 5923310 5923852 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acetolactate synthase III, small subunit 5923310..5923852 Methylobacterium extorquens DM4 8195009 YP_003071327.1 CDS METDI5925 NC_012988.1 5923915 5924559 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase 5923915..5924559 Methylobacterium extorquens DM4 8195595 YP_003071328.1 CDS METDI5926 NC_012988.1 5924785 5926554 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498721; Product type pe : putative enzyme; putative asparagine synthase, glutamine-hydrolyzing 5924785..5926554 Methylobacterium extorquens DM4 8195010 YP_003071329.1 CDS METDI5927 NC_012988.1 5926710 5927549 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aminohydrolase/amidotransferase 5926710..5927549 Methylobacterium extorquens DM4 8195011 YP_003071330.1 CDS METDI5928 NC_012988.1 5927692 5928438 R Evidence 2b : Function of strongly homologous gene; Product type f : factor; RNA polymerase sigma factor complement(5927692..5928438) Methylobacterium extorquens DM4 8195012 YP_003071331.1 CDS METDI5929 NC_012988.1 5928726 5930687 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5928726..5930687 Methylobacterium extorquens DM4 8195013 YP_003071332.1 CDS METDI5930 NC_012988.1 5930842 5931108 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5930842..5931108 Methylobacterium extorquens DM4 8195014 YP_003071333.1 CDS METDI5931 NC_012988.1 5931329 5932375 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hybrid histidine kinase complement(5931329..5932375) Methylobacterium extorquens DM4 8195015 YP_003071334.1 CDS METDI5932 NC_012988.1 5932372 5932785 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator receiver (CheY-like protein) complement(5932372..5932785) Methylobacterium extorquens DM4 8195016 YP_003071335.1 CDS METDI5933 NC_012988.1 5932821 5934719 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative histidine kinase complement(5932821..5934719) Methylobacterium extorquens DM4 8195017 YP_003071336.1 CDS METDI5934 NC_012988.1 5935073 5935945 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative regulatory protein, Crp (cAMP receptor protein) 5935073..5935945 Methylobacterium extorquens DM4 8195018 YP_003071337.1 CDS METDI5935 NC_012988.1 5935994 5937925 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative response regulator with unusual domain prganisation: Domains: GAF, PAS, PAC, CheY-like and HTHLuxR complement(5935994..5937925) Methylobacterium extorquens DM4 8195019 YP_003071338.1 CDS METDI5936 NC_012988.1 5938680 5938904 R Evidence 6 : Doubtful CDS; hypothetical protein complement(5938680..5938904) Methylobacterium extorquens DM4 8195020 YP_003071339.1 CDS METDI5937 NC_012988.1 5938957 5939280 D Evidence 6 : Doubtful CDS; hypothetical protein 5938957..5939280 Methylobacterium extorquens DM4 8195021 YP_003071340.1 CDS METDI5938 NC_012988.1 5939432 5939863 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5939432..5939863 Methylobacterium extorquens DM4 8195022 YP_003071341.1 CDS METDI5939 NC_012988.1 5939885 5940163 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5939885..5940163) Methylobacterium extorquens DM4 8195023 YP_003071342.1 CDS METDI5940 NC_012988.1 5940447 5941199 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5940447..5941199 Methylobacterium extorquens DM4 8195024 YP_003071343.1 CDS METDI5941 NC_012988.1 5941773 5941976 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5941773..5941976) Methylobacterium extorquens DM4 8195025 YP_003071344.1 CDS METDI5942 NC_012988.1 5941953 5942165 D Evidence 6 : Doubtful CDS; hypothetical protein 5941953..5942165 Methylobacterium extorquens DM4 8195026 YP_003071345.1 CDS METDI5943 NC_012988.1 5942385 5942624 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5942385..5942624 Methylobacterium extorquens DM4 8195027 YP_003071346.1 CDS METDI5944 NC_012988.1 5942774 5942956 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(5942774..5942956) Methylobacterium extorquens DM4 8195028 YP_003071347.1 CDS rpsT NC_012988.1 5943401 5943667 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 5943401..5943667 Methylobacterium extorquens DM4 8196266 YP_003071348.1 CDS pta NC_012989.1 15 1034 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10094701; Product type e : enzyme; Phosphate acetyltransferase (Phosphotransacetylase) 15..1034 Methylobacterium extorquens DM4 8196423 YP_003071349.1 CDS ackA NC_012989.1 1031 2206 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10094701; Product type e : enzyme; acetate kinase 1031..2206 Methylobacterium extorquens DM4 8196422 YP_003071350.1 CDS p2METDI0003 NC_012989.1 3132 4169 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator protein (AraC family) complement(3132..4169) Methylobacterium extorquens DM4 8196415 YP_003071351.1 CDS p2METDI0004 NC_012989.1 4282 4743 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative Regulator of ribonuclease activity A 4282..4743 Methylobacterium extorquens DM4 8196424 YP_003071352.1 CDS p2METDI0005 NC_012989.1 4743 5339 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4743..5339 Methylobacterium extorquens DM4 8196425 YP_003071353.1 CDS p2METDI0006 NC_012989.1 5606 6517 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Homoserine kinase complement(5606..6517) Methylobacterium extorquens DM4 8196426 YP_003071354.1 CDS pinE NC_012989.1 6773 7315 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; e14 prophage; inversion of adjacent DNA 6773..7315 Methylobacterium extorquens DM4 8196386 YP_003071355.1 CDS p2METDI0008 NC_012989.1 7320 7760 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 7320..7760 Methylobacterium extorquens DM4 8196421 YP_003071356.1 CDS p2METDI0009 NC_012989.1 7913 8596 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 7913..8596 Methylobacterium extorquens DM4 8196387 YP_003071357.1 CDS p2METDI0010 NC_012989.1 8640 8837 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 8640..8837 Methylobacterium extorquens DM4 8196388 YP_003071358.1 CDS p2METDI0011 NC_012989.1 8957 9733 D Evidence 2b : Function of strongly homologous gene; hypothetical protein 8957..9733 Methylobacterium extorquens DM4 8196389 YP_003071359.1 CDS p2METDI0012 NC_012989.1 10287 10943 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATPase, putative partition protein (ParA) 10287..10943 Methylobacterium extorquens DM4 8196390 YP_003071360.1 CDS p2METDI0013 NC_012989.1 10999 11214 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 10999..11214 Methylobacterium extorquens DM4 8196391 YP_003071361.1 CDS p2METDI0014 NC_012989.1 11383 12399 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 11383..12399 Methylobacterium extorquens DM4 8196392 YP_003071362.1 CDS p2METDI0015 NC_012989.1 12567 13877 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex3, IS256 family 12567..13877 Methylobacterium extorquens DM4 8196393 YP_003071363.1 CDS p2METDI0016 NC_012989.1 14697 16064 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 14697..16064 Methylobacterium extorquens DM4 8196394 YP_003071364.1 CDS p2METDI0018 NC_012989.1 15726 17114 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(15726..17114) Methylobacterium extorquens DM4 8196396 YP_003071365.1 CDS p2METDI0019 NC_012989.1 17129 18208 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(17129..18208) Methylobacterium extorquens DM4 8196397 YP_003071366.1 CDS p2METDI0020 NC_012989.1 18372 19178 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(18372..19178) Methylobacterium extorquens DM4 8196398 YP_003071367.1 CDS p2METDI0021 NC_012989.1 19196 20026 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(19196..20026) Methylobacterium extorquens DM4 8196399 YP_003071368.1 CDS p2METDI0022 NC_012989.1 20077 20514 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(20077..20514) Methylobacterium extorquens DM4 8196400 YP_003071369.1 CDS p2METDI0023 NC_012989.1 20799 21098 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 20799..21098 Methylobacterium extorquens DM4 8196401 YP_003071370.1 CDS p2METDI0024 NC_012989.1 21119 24472 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 21119..24472 Methylobacterium extorquens DM4 8196402 YP_003071371.1 CDS p2METDI0025 NC_012989.1 25245 26303 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Endonuclease/exonuclease/phosphatase 25245..26303 Methylobacterium extorquens DM4 8196403 YP_003071372.1 CDS p2METDI0026 NC_012989.1 26264 26410 R Evidence 6 : Doubtful CDS; hypothetical protein complement(26264..26410) Methylobacterium extorquens DM4 8196404 YP_003071373.1 CDS arsB NC_012989.1 26456 27751 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15004242, 1535622, 7721697, 95355341; Product type t : transporter; arsenical pump (Ars family) complement(26456..27751) Methylobacterium extorquens DM4 8196405 YP_003071374.1 CDS arsC NC_012989.1 27786 28211 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16905151, 17432936; Product type e : enzyme; arsenate reductase (glutaredoxin family) complement(27786..28211) Methylobacterium extorquens DM4 8196416 YP_003071375.1 CDS arsC NC_012989.1 28211 28738 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11573087, 16905151; Product type e : enzyme; arsenate reductase / phosphotyrosine protein phosphatase complement(28211..28738) Methylobacterium extorquens DM4 8196417 YP_003071376.1 CDS arsR NC_012989.1 28731 29093 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346, 12829264, 9537360; Product type r : regulator; transcriptional regulator, ArsR family complement(28731..29093) Methylobacterium extorquens DM4 8196418 YP_003071377.1 CDS p2METDI0031 NC_012989.1 29141 29887 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; NADPH-dependent FMN reductase 29141..29887 Methylobacterium extorquens DM4 8196419 YP_003071378.1 CDS p2METDI0032 NC_012989.1 30105 30515 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(30105..30515) Methylobacterium extorquens DM4 8196406 YP_003071379.1 CDS p2METDI0033 NC_012989.1 30737 31000 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(30737..31000) Methylobacterium extorquens DM4 8196407 YP_003071380.1 CDS p2METDI0035 NC_012989.1 31958 33079 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase of ISMex18, IS630 family complement(31958..33079) Methylobacterium extorquens DM4 8196409 YP_003071381.1 CDS p2METDI0038 NC_012989.1 33986 34234 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 33986..34234 Methylobacterium extorquens DM4 8196412 YP_003071382.1 CDS p2METDI0039 NC_012989.1 34251 34457 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(34251..34457) Methylobacterium extorquens DM4 8196413 YP_003071383.1 CDS fabI NC_012989.1 34969 35724 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10398587, 2687243; Product type e : enzyme; Enoyl-[acyl-carrier-protein] reductase (NADH) 34969..35724 Methylobacterium extorquens DM4 8196414 YP_003071384.1 CDS p2METDI0041 NC_012989.1 35988 38207 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 35988..38207 Methylobacterium extorquens DM4 8196420 METDMtRNA58 tRNA trnM NC_012988.1 52943 53019 R tRNA-Met complement(52943..53019) Methylobacterium extorquens DM4 8190577 METDMtRNA1 tRNA trnE NC_012988.1 61827 61901 D tRNA-Glu 61827..61901 Methylobacterium extorquens DM4 8196082 METDMtRNA57 tRNA trnS NC_012988.1 146033 146122 R tRNA-Ser complement(146033..146122) Methylobacterium extorquens DM4 8190646 METDMtRNA56 tRNA trnV NC_012988.1 157221 157295 R tRNA-Val complement(157221..157295) Methylobacterium extorquens DM4 8190651 METDMtRNA2 tRNA trnS NC_012988.1 232397 232489 D tRNA-Ser 232397..232489 Methylobacterium extorquens DM4 8190698 METDMtRNA55 tRNA trnG NC_012988.1 510472 510545 R tRNA-Gly complement(510472..510545) Methylobacterium extorquens DM4 8190960 METDMtRNA54 tRNA trnM NC_012988.1 526161 526237 R tRNA-Met complement(526161..526237) Methylobacterium extorquens DM4 8195249 METDMtRNA53 tRNA trnA NC_012988.1 529703 529778 R tRNA-Ala complement(529703..529778) Methylobacterium extorquens DM4 8196077 METDMtRNA52 tRNA trnI NC_012988.1 529785 529861 R tRNA-Ile complement(529785..529861) Methylobacterium extorquens DM4 8196220 METDMtRNA51 tRNA trnL NC_012988.1 759364 759448 R tRNA-Leu complement(759364..759448) Methylobacterium extorquens DM4 8191144 METDMtRNA3 tRNA trnS NC_012988.1 774084 774173 D tRNA-Ser 774084..774173 Methylobacterium extorquens DM4 8191154 METDMtRNA50 tRNA trnM NC_012988.1 857089 857165 R tRNA-Met complement(857089..857165) Methylobacterium extorquens DM4 8191253 METDMtRNA49 tRNA trnA NC_012988.1 860631 860706 R tRNA-Ala complement(860631..860706) Methylobacterium extorquens DM4 8196078 METDMtRNA48 tRNA trnI NC_012988.1 860713 860789 R tRNA-Ile complement(860713..860789) Methylobacterium extorquens DM4 8196219 METDMtRNA4 tRNA trnE NC_012988.1 1065702 1065777 D tRNA-Glu 1065702..1065777 Methylobacterium extorquens DM4 8191412 METDMtRNA47 tRNA trnM NC_012988.1 1335283 1335359 R tRNA-Met complement(1335283..1335359) Methylobacterium extorquens DM4 8191689 METDMtRNA46 tRNA trnA NC_012988.1 1338825 1338900 R tRNA-Ala complement(1338825..1338900) Methylobacterium extorquens DM4 8196079 METDMtRNA45 tRNA trnI NC_012988.1 1338907 1338983 R tRNA-Ile complement(1338907..1338983) Methylobacterium extorquens DM4 8196218 METDMtRNA44 tRNA trnM NC_012988.1 1357540 1357616 R tRNA-Met complement(1357540..1357616) Methylobacterium extorquens DM4 8191704 METDMtRNA43 tRNA trnA NC_012988.1 1361082 1361157 R tRNA-Ala complement(1361082..1361157) Methylobacterium extorquens DM4 8196080 METDMtRNA42 tRNA trnI NC_012988.1 1361164 1361240 R tRNA-Ile complement(1361164..1361240) Methylobacterium extorquens DM4 8196217 METDMtRNA5 tRNA trnD NC_012988.1 1432697 1432773 D tRNA-Asp 1432697..1432773 Methylobacterium extorquens DM4 8195787 METDMtRNA41 tRNA trnR NC_012988.1 1798130 1798206 R tRNA-Arg complement(1798130..1798206) Methylobacterium extorquens DM4 8192025 METDMtRNA40 tRNA trnM NC_012988.1 1899208 1899284 R tRNA-Met complement(1899208..1899284) Methylobacterium extorquens DM4 8192124 METDMtRNA39 tRNA trnI NC_012988.1 1902750 1902825 R tRNA-Ala complement(1902750..1902825) Methylobacterium extorquens DM4 8196081 METDMtRNA38 tRNA trnI NC_012988.1 1902832 1902908 R tRNA-Ile complement(1902832..1902908) Methylobacterium extorquens DM4 8196231 METDMtRNA6 tRNA trnR NC_012988.1 1905935 1906011 D tRNA-Arg 1905935..1906011 Methylobacterium extorquens DM4 8196088 METDMtRNA7 tRNA trnG NC_012988.1 2227106 2227180 D tRNA-Gly 2227106..2227180 Methylobacterium extorquens DM4 8192335 METDMtRNA8 tRNA trnI NC_012988.1 2477003 2477074 D tRNA-Ile 2477003..2477074 Methylobacterium extorquens DM4 8192519 METDMtRNA9 tRNA trnV NC_012988.1 2627598 2627672 D tRNA-Val 2627598..2627672 Methylobacterium extorquens DM4 8192636 METDMtRNA10 tRNA trnT NC_012988.1 2835288 2835363 D tRNA-Thr 2835288..2835363 Methylobacterium extorquens DM4 8192770 METDMtRNA37 tRNA trnL NC_012988.1 2893887 2893973 R tRNA-Leu complement(2893887..2893973) Methylobacterium extorquens DM4 8192808 METDMtRNA11 tRNA trnL NC_012988.1 3102710 3102794 D tRNA-Leu 3102710..3102794 Methylobacterium extorquens DM4 8192956 METDMtRNA12 tRNA trnV NC_012988.1 3109465 3109540 D tRNA-Val 3109465..3109540 Methylobacterium extorquens DM4 8195643 METDMtRNA13 tRNA trnA NC_012988.1 3118642 3118717 D tRNA-Ala 3118642..3118717 Methylobacterium extorquens DM4 8192964 METDMtRNA36 tRNA trnF NC_012988.1 3293492 3293567 R tRNA-Phe complement(3293492..3293567) Methylobacterium extorquens DM4 8193065 METDMtRNA14 tRNA trnT NC_012988.1 3294713 3294788 D tRNA-Thr 3294713..3294788 Methylobacterium extorquens DM4 8193067 METDMtRNA15 tRNA trnY NC_012988.1 3460823 3460904 D tRNA-Tyr 3460823..3460904 Methylobacterium extorquens DM4 8195971 METDMtRNA35 tRNA trnH NC_012988.1 3482627 3482703 R tRNA-His complement(3482627..3482703) Methylobacterium extorquens DM4 8193195 METDMtRNA16 tRNA trnK NC_012988.1 3784013 3784088 D tRNA-Lys 3784013..3784088 Methylobacterium extorquens DM4 8193407 METDMtRNA17 tRNA trnP NC_012988.1 3849212 3849288 D tRNA-Pro 3849212..3849288 Methylobacterium extorquens DM4 8193463 METDMtRNA18 tRNA trnG NC_012988.1 4222079 4222153 D tRNA-Gly 4222079..4222153 Methylobacterium extorquens DM4 8193726 METDMtRNA34 tRNA trnM NC_012988.1 4455231 4455306 R tRNA-Met complement(4455231..4455306) Methylobacterium extorquens DM4 8193984 METDMtRNA19 tRNA trnS NC_012988.1 4562751 4562840 D tRNA-Ser 4562751..4562840 Methylobacterium extorquens DM4 8194079 METDMtRNA20 tRNA trnA NC_012988.1 4641080 4641155 D tRNA-Ala 4641080..4641155 Methylobacterium extorquens DM4 8194135 METDMtRNA21 tRNA trnA NC_012988.1 4655198 4655273 D tRNA-Ala 4655198..4655273 Methylobacterium extorquens DM4 8194149 METDMtRNA22 tRNA trnP NC_012988.1 4758201 4758277 D tRNA-Pro 4758201..4758277 Methylobacterium extorquens DM4 8194238 METDMtRNA23 tRNA trnR NC_012988.1 4758323 4758399 D tRNA-Arg 4758323..4758399 Methylobacterium extorquens DM4 8196253 METDMtRNA24 tRNA trnW NC_012988.1 4886604 4886680 D tRNA-Trp 4886604..4886680 Methylobacterium extorquens DM4 8194324 METDMtRNA33 tRNA trnL NC_012988.1 5137049 5137133 R tRNA-Leu complement(5137049..5137133) Methylobacterium extorquens DM4 8194486 METDMtRNA25 tRNA trnQ NC_012988.1 5288636 5288709 D tRNA-Gln 5288636..5288709 Methylobacterium extorquens DM4 8194592 METDMtRNA26 tRNA trnL NC_012988.1 5344579 5344663 D tRNA-Leu 5344579..5344663 Methylobacterium extorquens DM4 8195630 METDMtRNA27 tRNA trnQ NC_012988.1 5368047 5368121 D tRNA-Gln 5368047..5368121 Methylobacterium extorquens DM4 8194651 METDMtRNA28 tRNA trnP NC_012988.1 5522860 5522936 D tRNA-Pro 5522860..5522936 Methylobacterium extorquens DM4 8194747 METDMtRNA32 tRNA trnC NC_012988.1 5741509 5741582 R tRNA-Cys complement(5741509..5741582) Methylobacterium extorquens DM4 8194902 METDMtRNA29 tRNA trnN NC_012988.1 5741826 5741901 D tRNA-Asn 5741826..5741901 Methylobacterium extorquens DM4 8196221 METDMtRNA30 tRNA trnK NC_012988.1 5903116 5903191 D tRNA-Lys 5903116..5903191 Methylobacterium extorquens DM4 8195550 METDMtRNA31 tRNA trnT NC_012988.1 5943044 5943118 R tRNA-Thr complement(5943044..5943118) Methylobacterium extorquens DM4 8195029 METDI_5S_1 rRNA rrf NC_012988.1 526303 526407 R ribosomal RNA 5S (rRNA operon 1) complement(526303..526407) Methylobacterium extorquens DM4 8196249 METDI_23S_1 rRNA rrl NC_012988.1 526571 529411 R ribosomal RNA 23S (rRNA operon 1) complement(526571..529411) Methylobacterium extorquens DM4 8196072 METDI_16S_1 rRNA rrs NC_012988.1 530014 531491 R ribosomal RNA 16S (rRNA operon 1) complement(530014..531491) Methylobacterium extorquens DM4 8196235 METDI_5S_2 rRNA rrf NC_012988.1 857231 857335 R ribosomal RNA 5S (rRNA operon 2) complement(857231..857335) Methylobacterium extorquens DM4 8196248 METDI_23S_2 rRNA rrl NC_012988.1 857499 860339 R ribosomal RNA 23S (rRNA operon 2) complement(857499..860339) Methylobacterium extorquens DM4 8196073 METDI_16S_2 rRNA rrs NC_012988.1 860942 862419 R ribosomal RNA 16S (rRNA operon 2) complement(860942..862419) Methylobacterium extorquens DM4 8196234 METDI_5S_3 rRNA rrf NC_012988.1 1335425 1335529 R ribosomal RNA 5S (rRNA operon 3) complement(1335425..1335529) Methylobacterium extorquens DM4 8196247 METDI_23S_3 rRNA rrl NC_012988.1 1335693 1338533 R ribosomal RNA 23S (rRNA operon 3) complement(1335693..1338533) Methylobacterium extorquens DM4 8196074 METDI_16S_3 rRNA rrs NC_012988.1 1339136 1340613 R ribosomal RNA 16S (rRNA operon 3) complement(1339136..1340613) Methylobacterium extorquens DM4 8196233 METDI_5S_4 rRNA rrf NC_012988.1 1357682 1357786 R ribosomal RNA 5S (rRNA operon 4) complement(1357682..1357786) Methylobacterium extorquens DM4 8196246 METDI_23S_4 rRNA rrl NC_012988.1 1357950 1360790 R ribosomal RNA 23S (rRNA operon 4) complement(1357950..1360790) Methylobacterium extorquens DM4 8196075 METDI_16S_4 rRNA rrs NC_012988.1 1361393 1362870 R ribosomal RNA 16S (rRNA operon 4) complement(1361393..1362870) Methylobacterium extorquens DM4 8196232 METDI_5S_5 rRNA rrf NC_012988.1 1899351 1899455 R ribosomal RNA 5S (rRNA operon 5) complement(1899351..1899455) Methylobacterium extorquens DM4 8196245 METDI_23S_5 rRNA rrl NC_012988.1 1899618 1902458 R ribosomal RNA 23S (rRNA operon 5) complement(1899618..1902458) Methylobacterium extorquens DM4 8196076 METDI_16S_5 rRNA rrs NC_012988.1 1903061 1904538 R ribosomal RNA 16S (rRNA operon 5) complement(1903061..1904538) Methylobacterium extorquens DM4 8196230