-- dump date 20111121_013243 -- class Genbank::CDS -- table cds_note -- id note YP_002956130.1 PFAM: Bacterial dnaA protein; Bacterial dnaA protein helix-turn-helix domain; TIGRFAM: chromosomal replication initiator protein DnaA YP_002956131.1 PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, central domain; DNA polymerase III beta subunit, N-terminal domain; TIGRFAM: DNA polymerase III, beta subunit YP_002956132.1 PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein YP_002956133.1 PFAM: Protein of unknown function (DUF721) YP_002956134.1 negatively supercoils closed circular double-stranded DNA YP_002956135.1 negatively supercoils closed circular double-stranded DNA YP_002956146.1 PFAM: Methyltransferase domain YP_002956148.1 PFAM: Peptidase family M23 YP_002956150.1 PFAM: ParB-like nuclease domain YP_002956154.1 PFAM: Primase C terminal 1 (PriCT-1); Bifunctional DNA primase/polymerase, N-terminal YP_002956156.1 PFAM: Transposase, Mutator family YP_002956157.1 PFAM: Domain of unknown function (DUF955) YP_002956158.1 PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_002956159.1 PFAM: FAD binding domain YP_002956161.1 PFAM: Bacterial regulatory proteins, tetR family YP_002956163.1 PFAM: TrwC relaxase; TIGRFAM: conjugative relaxase domain, TrwC/TraI family YP_002956167.1 PFAM: Transposase, Mutator family YP_002956168.1 PFAM: Transposase, Mutator family YP_002956171.1 PFAM: Transposase YP_002956175.1 PFAM: Integrase core domain YP_002956177.1 PFAM: Transposase YP_002956178.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002956179.1 PFAM: GrpE YP_002956180.1 PFAM: DnaJ C terminal region; DnaJ domain YP_002956182.1 PFAM: C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_002956183.1 PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_002956185.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cyclic nucleotide-binding domain YP_002956187.1 PFAM: Uncharacterized ACR, YhhQ family COG1738; TIGRFAM: conserved hypothetical integral membrane protein; ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_002956189.1 PFAM: Metallo-beta-lactamase superfamily YP_002956191.1 PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_002956192.1 PFAM: Rhomboid family YP_002956193.1 PFAM: Uncharacterised protein family (UPF0233) YP_002956194.1 PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_002956195.1 PFAM: Protein kinase domain; PASTA domain YP_002956196.1 PFAM: Protein kinase domain YP_002956197.1 PFAM: Penicillin binding protein transpeptidase domain YP_002956198.1 PFAM: Cell cycle protein YP_002956199.1 PFAM: Protein phosphatase 2C YP_002956200.1 PFAM: FHA domain YP_002956201.1 PFAM: FHA domain YP_002956202.1 PFAM: Universal stress protein family YP_002956203.1 PFAM: Bordetella uptake gene (bug) product YP_002956205.1 PFAM: Integral membrane protein DUF112 YP_002956206.1 PFAM: HpcH/HpaI aldolase/citrate lyase family YP_002956207.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase YP_002956208.1 PFAM: YceI-like domain YP_002956209.1 PFAM: Dienelactone hydrolase family YP_002956211.1 PFAM: Aminotransferase class-III YP_002956212.1 PFAM: Permease family; TIGRFAM: uracil-xanthine permease YP_002956213.1 PFAM: pfkB family carbohydrate kinase YP_002956214.1 catalyzes the oxidation of malate to oxaloacetate YP_002956215.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_002956216.1 PFAM: Protein of unknown function DUF88 YP_002956218.1 PFAM: Amino acid permease YP_002956219.1 PFAM: Beta-eliminating lyase YP_002956220.1 PFAM: short chain dehydrogenase YP_002956222.1 PFAM: LexA DNA binding domain; AsnC family YP_002956223.1 PFAM: Glycerophosphoryl diester phosphodiesterase family YP_002956224.1 PFAM: Aldehyde dehydrogenase family YP_002956225.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002956226.1 PFAM: Ferric uptake regulator family YP_002956228.1 PFAM: GlcNAc-PI de-N-acetylase; Methyltransferase domain YP_002956230.1 PFAM: Amidase YP_002956231.1 PFAM: Rhodanese-like domain YP_002956232.1 PFAM: Prephenate dehydratase; ACT domain YP_002956233.1 PFAM: Diacylglycerol kinase catalytic domain YP_002956234.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002956235.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_002956237.1 PFAM: Inorganic pyrophosphatase YP_002956238.1 PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family YP_002956239.1 PFAM: Uncharacterised conserved protein (DUF2342) YP_002956240.1 PFAM: PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, N-terminal domain YP_002956241.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_002956243.1 PFAM: Peptidase family M41; FtsH Extracellular; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_002956244.1 PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_002956245.1 PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_002956246.1 PFAM: Dihydroneopterin aldolase; TIGRFAM: FolB domain; dihydroneopterin aldolase YP_002956247.1 PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_002956249.1 PFAM: Bacterial membrane flanked domain YP_002956250.1 PFAM: Bacterial membrane flanked domain YP_002956251.1 PFAM: Rossmann-like domain; Domain of unknown function (DUF2520) YP_002956252.1 PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_002956254.1 PFAM: Prolyl oligopeptidase family YP_002956255.1 PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_002956256.1 PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase YP_002956257.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase YP_002956258.1 PFAM: Citrate transporter YP_002956259.1 PFAM: Glycerophosphoryl diester phosphodiesterase family YP_002956261.1 PFAM: Protein of unknown function (DUF1469) YP_002956263.1 PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase YP_002956264.1 PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: DNA-3-methyladenine glycosylase (3mg) YP_002956265.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_002956266.1 PFAM: Peptidase family M13; Peptidase family M13 YP_002956267.1 PFAM: MarR family YP_002956268.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_002956269.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_002956270.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002956273.1 PFAM: ATPase family associated with various cellular activities (AAA); C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); Clp amino terminal domain YP_002956275.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis YP_002956276.1 PFAM: Helix-hairpin-helix motif; Iron-sulfur binding domain of endonuclease III; TIGRFAM: A/G-specific adenine glycosylase YP_002956278.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002956280.1 TIGRFAM: phosphate ABC transporter, phosphate-binding protein YP_002956281.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC YP_002956282.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA YP_002956283.1 PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_002956284.1 PFAM: Phosphate transporter family YP_002956287.1 PFAM: Phospholipase/Carboxylesterase YP_002956289.1 PFAM: Protein of unknown function (DUF445) YP_002956290.1 PFAM: Glycerophosphoryl diester phosphodiesterase family YP_002956291.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_002956292.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002956293.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002956294.1 PFAM: Oligopeptide/dipeptide transporter, C-terminal region; ABC transporter; TIGRFAM: phosphonate C-P lyase system protein PhnK YP_002956295.1 PFAM: Acetokinase family; TIGRFAM: acetate kinase YP_002956296.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002956298.1 PFAM: Domain of unknown function DUF77; TIGRFAM: conserved hypothetical protein TIGR00106 YP_002956299.1 PFAM: Acetyltransferase (GNAT) family YP_002956301.1 PFAM: Universal stress protein family YP_002956302.1 PFAM: Domain of unknown function (DUF1025) YP_002956303.1 PFAM: Isochorismatase family YP_002956305.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_002956306.1 PFAM: Amino acid permease YP_002956307.1 PFAM: Alpha amylase, catalytic domain YP_002956308.1 PFAM: Nitroreductase family YP_002956310.1 PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III (xth); exodeoxyribonuclease III YP_002956311.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002956313.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002956314.1 PFAM: Transposase DDE domain YP_002956316.1 PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA) YP_002956318.1 PFAM: SpoU rRNA Methylase family YP_002956319.1 PFAM: SMP-30/Gluconolaconase/LRE-like region YP_002956320.1 PFAM: Secretory lipase YP_002956321.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002956322.1 PFAM: Domain of unknown function (DUF955); Helix-turn-helix YP_002956323.1 PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase YP_002956324.1 PFAM: Malate synthase; TIGRFAM: malate synthase A YP_002956327.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002956329.1 PFAM: MerR family regulatory protein; TIGRFAM: DNA binding domain, excisionase family YP_002956330.1 PFAM: Transposase, Mutator family YP_002956331.1 PFAM: Acetyltransferase (GNAT) family YP_002956333.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_002956335.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002956336.1 PFAM: Catalase-related immune-responsive; Catalase YP_002956337.1 PFAM: Carbon-nitrogen hydrolase YP_002956339.1 PFAM: IclR helix-turn-helix domain YP_002956340.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002956341.1 PFAM: Nucleoside recognition YP_002956342.1 catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002956343.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002956345.1 PFAM: Helix-turn-helix YP_002956346.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_002956347.1 PFAM: CoA binding domain YP_002956348.1 PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_002956350.1 PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family YP_002956351.1 PFAM: Protein of unknown function (DUF1648) YP_002956352.1 PFAM: Integral membrane protein DUF6 YP_002956353.1 PFAM: Siderophore-interacting protein; Siderophore-interacting FAD-binding domain YP_002956355.1 PFAM: Peptidase family M20/M25/M40; TIGRFAM: amidohydrolase YP_002956356.1 PFAM: AMP-binding enzyme; TIGRFAM: acetate--CoA ligase YP_002956357.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain YP_002956358.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002956363.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002956364.1 TIGRFAM: phosphoribosylformylglycinamidine synthase I YP_002956365.1 PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein YP_002956366.1 PFAM: SEC-C motif YP_002956368.1 PFAM: Helix-turn-helix YP_002956370.1 PFAM: Protein of unknown function (DUF952); Acetyltransferase (GNAT) family YP_002956371.1 PFAM: TAP-like protein; alpha/beta hydrolase fold YP_002956373.1 PFAM: Peptidase inhibitor I9; Subtilase family YP_002956374.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_002956375.1 PFAM: ABC transporter YP_002956377.1 PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_002956378.1 PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, subunits gamma and tau YP_002956379.1 PFAM: Nitroreductase family YP_002956380.1 PFAM: tRNA synthetases class I (E and Q), catalytic domain YP_002956381.1 PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_002956382.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, central domain YP_002956385.1 PFAM: Staphylococcal nuclease homologue YP_002956386.1 PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_002956387.1 PFAM: Serine dehydratase beta chain; Serine dehydratase alpha chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form YP_002956388.1 PFAM: NUDIX domain YP_002956389.1 PFAM: Electron transfer flavoprotein domain YP_002956390.1 PFAM: Electron transfer flavoprotein FAD-binding domain; Electron transfer flavoprotein domain YP_002956393.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_002956394.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_002956395.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_002956396.1 PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase YP_002956397.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase YP_002956398.1 PFAM: short chain dehydrogenase YP_002956399.1 PFAM: MarR family YP_002956400.1 PFAM: AMP-binding enzyme YP_002956401.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_002956402.1 PFAM: Protein of unknown function (DUF1275) YP_002956403.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid YP_002956404.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002956405.1 PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: glycine cleavage system T protein YP_002956406.1 PFAM: Staphylococcal nuclease homologue YP_002956407.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_002956409.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002956412.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002956414.1 PFAM: Antibiotic biosynthesis monooxygenase YP_002956415.1 PFAM: Acetyltransferase (GNAT) family YP_002956416.1 PFAM: Bacterial regulatory proteins, tetR family YP_002956417.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_002956419.1 PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming YP_002956421.1 PFAM: Transposase, Mutator family YP_002956423.1 PFAM: Transposase YP_002956424.1 PFAM: Ornithine cyclodeaminase/mu-crystallin family YP_002956425.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002956426.1 PFAM: Integrase core domain YP_002956430.1 PFAM: NADH:flavin oxidoreductase / NADH oxidase family YP_002956434.1 PFAM: RNA pseudouridylate synthase YP_002956435.1 PFAM: Nucleotidyl transferase YP_002956436.1 PFAM: Formamidopyrimidine-DNA glycosylase N-terminal domain; Formamidopyrimidine-DNA glycosylase H2TH domain YP_002956437.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase YP_002956438.1 PFAM: SPOUT methyltransferase; TIGRFAM: conserved hypothetical protein TIGR00246 YP_002956440.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_002956441.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002956442.1 PFAM: Transcriptional regulatory protein, C terminal YP_002956443.1 PFAM: Phosphoglycerate mutase family YP_002956444.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_002956445.1 PFAM: Transposase, Mutator family YP_002956446.1 PFAM: Integrase core domain YP_002956447.1 PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit YP_002956448.1 PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit YP_002956449.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_002956450.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_002956451.1 PFAM: UreF YP_002956452.1 PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: urease accessory protein UreG YP_002956453.1 PFAM: UreD urease accessory protein YP_002956454.1 PFAM: High-affinity nickel-transport protein; TIGRFAM: high-affinity nickel-transporter, HoxN/HupN/NixA family YP_002956455.1 PFAM: Urea transporter YP_002956456.1 PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; Globin YP_002956457.1 PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein ( transcriptional regulator) YP_002956458.1 PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family YP_002956459.1 PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II YP_002956460.1 PFAM: Major Facilitator Superfamily YP_002956463.1 PFAM: PRC-barrel domain; Domain of unknown function (DUF2382); TIGRFAM: conserved domain YP_002956465.1 PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_002956466.1 PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain YP_002956467.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain; TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family YP_002956469.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphonatase-like hydrolase YP_002956470.1 TIGRFAM: DNA polymerase III, delta' subunit YP_002956471.1 PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_002956472.1 PFAM: Protein of unknown function (DUF2516) YP_002956474.1 PFAM: Phosphoglycerate mutase family; TIGRFAM: phosphoglycerate mutase, BPG-dependent, family 1 YP_002956475.1 PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU YP_002956476.1 PFAM: His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002956477.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_002956479.1 PFAM: CarD-like/TRCF domain YP_002956480.1 PFAM: Uncharacterized protein family UPF0007; YgbB family; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002956481.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002956482.1 PFAM: RNA 2'-O ribose methyltransferase substrate binding; SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, , group 3 YP_002956483.1 PFAM: ABC transporter substrate binding protein YP_002956484.1 PFAM: Branched-chain amino acid transport system / permease component YP_002956485.1 PFAM: ABC transporter YP_002956487.1 PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, C-terminal all-beta domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase YP_002956490.1 PFAM: Carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain YP_002956492.1 PFAM: NADP oxidoreductase coenzyme F420-dependent YP_002956493.1 PFAM: Fumarylacetoacetate (FAA) hydrolase family YP_002956494.1 PFAM: Aldo/keto reductase family YP_002956496.1 PFAM: Alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose synthase YP_002956497.1 PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose trehalohydrolase YP_002956499.1 PFAM: DSBA-like thioredoxin domain YP_002956500.1 PFAM: Subtilase family YP_002956501.1 PFAM: Protein of unknown function (DUF1212) YP_002956502.1 PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase YP_002956505.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002956507.1 PFAM: Proteins of 100 residues with WXG YP_002956508.1 PFAM: HAMP domain; His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002956509.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_002956512.1 PFAM: 'Cold-shock' DNA-binding domain YP_002956514.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_002956515.1 PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_002956516.1 PFAM: HNH endonuclease YP_002956517.1 PFAM: ABC transporter transmembrane region; ABC transporter YP_002956519.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2176) YP_002956521.1 PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA YP_002956522.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002956523.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002956524.1 PFAM: Integral membrane protein DUF125 YP_002956525.1 PFAM: Domain of unknown function DUF YP_002956527.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent YP_002956528.1 PFAM: Sodium:solute symporter family YP_002956529.1 PFAM: Helix-turn-helix; Cupin domain YP_002956530.1 PFAM: Arginase family; TIGRFAM: agmatinase YP_002956531.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, central domain YP_002956532.1 PFAM: Dioxygenase YP_002956533.1 PFAM: Pyridoxamine 5'-phosphate oxidase YP_002956534.1 PFAM: Inositol monophosphatase family YP_002956536.1 PFAM: Uncharacterized conserved protein (DUF2183) YP_002956539.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_002956540.1 PFAM: Glycosyl transferases group 1 YP_002956543.1 PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_002956544.1 PFAM: Major Facilitator Superfamily YP_002956545.1 involved in de novo purine biosynthesis YP_002956546.1 PFAM: Divalent cation transporter; CBS domain pair; MgtE intracellular N domain; TIGRFAM: Mg2+ transporter (mgtE) YP_002956548.1 PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type YP_002956549.1 PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_002956550.1 PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777 YP_002956551.1 PFAM: Glutaminase; Cyclic nucleotide-binding domain YP_002956552.1 PFAM: Helicase associated domain (HA2); ATP-dependent helicase C-terminal; Helicase conserved C-terminal domain; TIGRFAM: ATP-dependent helicase HrpB YP_002956553.1 PFAM: Bacterial extracellular solute-binding protein YP_002956554.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002956555.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002956556.1 PFAM: ABC transporter YP_002956557.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_002956558.1 PFAM: Bacterial transferase hexapeptide (three repeats) YP_002956559.1 PFAM: Formyl transferase; ACT domain; TIGRFAM: formyltetrahydrofolate deformylase YP_002956561.1 PFAM: Catalase-related immune-responsive; Catalase YP_002956562.1 PFAM: Transposase YP_002956563.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002956564.1 PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_002956565.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever YP_002956566.1 PFAM: ABC transporter; TIGRFAM: ATP-binding ABC transporter family nodulation protein NodI YP_002956567.1 PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family YP_002956568.1 PFAM: Major Facilitator Superfamily YP_002956570.1 PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_002956571.1 PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_002956572.1 PFAM: ABC transporter YP_002956573.1 PFAM: permease YP_002956577.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_002956578.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002956580.1 PFAM: Succinate dehydrogenase cytochrome b subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit YP_002956581.1 PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_002956582.1 PFAM: Peptidase family M20/M25/M40; TIGRFAM: amidohydrolase YP_002956583.1 PFAM: Transposase YP_002956584.1 PFAM: Basic membrane protein YP_002956585.1 PFAM: ABC transporter YP_002956586.1 PFAM: Branched-chain amino acid transport system / permease component YP_002956587.1 PFAM: Branched-chain amino acid transport system / permease component YP_002956588.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_002956589.1 PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase YP_002956590.1 PFAM: SNARE associated Golgi protein YP_002956591.1 catalyzes the formation of inosine from adenosine YP_002956592.1 PFAM: MazG nucleotide pyrophosphohydrolase domain YP_002956593.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002956594.1 PFAM: Septum formation initiator YP_002956595.1 PFAM: Protein of unknown function (DUF501); Ppx/GppA phosphatase family YP_002956596.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_002956597.1 PFAM: Protein of unknown function (DUF1112) YP_002956598.1 PFAM: Aldose 1-epimerase YP_002956599.1 PFAM: Domain of unknown function DUF20 YP_002956600.1 catalyzes the formation of 2-oxobutanoate from L-threonine YP_002956602.1 PFAM: Prokaryotic transcription elongation factor, GreA/GreB, N-terminal domain; Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain; TIGRFAM: transcription elongation factor GreA YP_002956604.1 PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: mycothiol conjugate amidase Mca YP_002956606.1 PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family YP_002956607.1 PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_002956608.1 PFAM: Rhomboid family YP_002956609.1 PFAM: PhoH-like protein YP_002956610.1 PFAM: Type IV leader peptidase family YP_002956611.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002956612.1 PFAM: Carbonic anhydrase YP_002956614.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002956615.1 PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I YP_002956616.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_002956617.1 PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_002956618.1 PFAM: ATP-grasp domain; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurK protein YP_002956619.1 PFAM: GtrA-like protein YP_002956620.1 TIGRFAM: conserved hypothetical protein TIGR03089 YP_002956621.1 PFAM: Transcription factor WhiB YP_002956624.1 PFAM: Integrase core domain YP_002956625.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_002956626.1 TIGRFAM: integral membrane protein TIGR01906 YP_002956627.1 PFAM: AMP-binding enzyme YP_002956628.1 PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase YP_002956629.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: conserved hypothetical protein TIGR00096 YP_002956630.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase YP_002956631.1 PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_002956633.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002956634.1 PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_002956635.1 PFAM: ABC transporter YP_002956636.1 PFAM: Transposase, Mutator family YP_002956637.1 PFAM: Uncharacterized protein family UPF0007; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_002956639.1 PFAM: Domain of unknown function (DUF1814) YP_002956640.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002956641.1 PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_002956643.1 PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form YP_002956644.1 PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_002956646.1 PFAM: Protein of unknown function (DUF2505) YP_002956648.1 PFAM: TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; Helicase conserved C-terminal domain; TIGRFAM: transcription-repair coupling factor (mfd) YP_002956649.1 PFAM: Acyltransferase family YP_002956651.1 PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_002956652.1 PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_002956653.1 PFAM: Phosphorylase superfamily; TIGRFAM: purine nucleotide phosphorylase; inosine guanosine and xanthosine phosphorylase family YP_002956655.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; TIGRFAM: nucleotide sugar dehydrogenase YP_002956656.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity YP_002956657.1 PFAM: Glycosyl transferases group 1 YP_002956658.1 PFAM: Major Facilitator Superfamily; TIGRFAM: metabolite-proton symporter YP_002956659.1 PFAM: Biotin-requiring enzyme; Biotin carboxylase C-terminal domain; ATP-grasp domain; Carbamoyl-phosphate synthase L chain, N-terminal domain YP_002956660.1 PFAM: Maf-like protein; TIGRFAM: MAF protein YP_002956661.1 PFAM: Bacterial protein of unknown function (DUF885) YP_002956663.1 PFAM: Glycosyl transferases group 1 YP_002956664.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase YP_002956665.1 PFAM: Glycosyl transferases group 1 YP_002956666.1 PFAM: Aldo/keto reductase family YP_002956667.1 PFAM: FAD dependent oxidoreductase; GMC oxidoreductase YP_002956668.1 PFAM: Bacterial transferase hexapeptide (three repeats) YP_002956669.1 PFAM: Glycosyl transferases group 1 YP_002956671.1 PFAM: Glycosyl transferases group 1 YP_002956672.1 PFAM: Acyltransferase family YP_002956675.1 PFAM: Polysaccharide biosynthesis protein YP_002956677.1 PFAM: Chain length determinant protein; TIGRFAM: capsular exopolysaccharide family YP_002956680.1 PFAM: Carboxyl transferase domain YP_002956681.1 PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region YP_002956683.1 PFAM: Adenylate and Guanylate cyclase catalytic domain YP_002956684.1 PFAM: Stage II sporulation protein E (SpoIIE) YP_002956685.1 PFAM: BRCA1 C Terminus (BRCT) domain; NAD-dependent DNA ligase C4 zinc finger domain; NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; TIGRFAM: DNA ligase, NAD-dependent YP_002956686.1 PFAM: Inositol monophosphatase family YP_002956688.1 PFAM: Acetyltransferase (GNAT) family YP_002956689.1 PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit YP_002956690.1 PFAM: Amidase; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit YP_002956691.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002956692.1 PFAM: Phosphotransferase enzyme family YP_002956695.1 PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_002956696.1 PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase YP_002956697.1 PFAM: GDSL-like Lipase/Acylhydrolase YP_002956698.1 PFAM: Phospholipase/Carboxylesterase YP_002956700.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002956703.1 PFAM: Major Facilitator Superfamily YP_002956705.1 PFAM: MerR, DNA binding; MerR family regulatory protein YP_002956706.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: mercuric reductase YP_002956711.1 PFAM: Recombinase; Resolvase, N terminal domain YP_002956712.1 PFAM: Luciferase-like monooxygenase YP_002956713.1 PFAM: Ankyrin repeat YP_002956714.1 PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, nifR3 family YP_002956715.1 PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, ; uncharacterized domain HDIG YP_002956716.1 PFAM: TOBE domain; ABC transporter YP_002956717.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002956718.1 PFAM: Bacterial extracellular solute-binding protein YP_002956719.1 PFAM: Sir2 family YP_002956720.1 PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade YP_002956721.1 PFAM: Sodium Bile acid symporter family YP_002956723.1 synthesizes RNA primers at the replication forks YP_002956724.1 PFAM: Peptidase propeptide and YPEB domain YP_002956729.1 PFAM: Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_002956735.1 PFAM: Transposase, Mutator family YP_002956742.1 PFAM: Transposase DDE domain YP_002956744.1 PFAM: Transposase DDE domain YP_002956745.1 PFAM: Integrase core domain YP_002956746.1 PFAM: Transposase YP_002956747.1 PFAM: Phage integrase family YP_002956748.1 PFAM: Phage integrase family YP_002956750.1 PFAM: alpha/beta hydrolase fold YP_002956751.1 PFAM: Protein of unknown function DUF72 YP_002956752.1 PFAM: short chain dehydrogenase YP_002956753.1 PFAM: Inosine-uridine preferring nucleoside hydrolase YP_002956754.1 PFAM: Aldo/keto reductase family YP_002956755.1 PFAM: Protein of unknown function (DUF1469) YP_002956756.1 PFAM: CDP-alcohol phosphatidyltransferase YP_002956757.1 PFAM: Glycosyl transferases group 1 YP_002956758.1 PFAM: LysM domain; NlpC/P60 family YP_002956759.1 PFAM: Glycosyl transferases group 1 YP_002956760.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002956761.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002956762.1 PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase YP_002956763.1 PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_002956764.1 PFAM: Cytidylyltransferase family YP_002956766.1 PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit YP_002956767.1 PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain YP_002956768.1 PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme YP_002956769.1 PFAM: Acetyltransferase (GNAT) family YP_002956770.1 PFAM: Bacterial regulatory proteins, tetR family YP_002956771.1 PFAM: Carboxyl transferase domain YP_002956772.1 PFAM: Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme YP_002956773.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_002956774.1 PFAM: MaoC like domain YP_002956775.1 PFAM: HpcH/HpaI aldolase/citrate lyase family YP_002956776.1 PFAM: Protein of unknown function, DUF485 YP_002956777.1 PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily YP_002956778.1 PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002956779.1 PFAM: Peptidase family M50; TIGRFAM: RIP metalloprotease RseP YP_002956780.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002956781.1 PFAM: Acetyltransferase (GNAT) family YP_002956782.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002956783.1 PFAM: Domain of unknown function DUF81 YP_002956784.1 PFAM: Uncharacterised BCR, YhbC family COG0779 YP_002956785.1 PFAM: NusA N-terminal domain; TIGRFAM: transcription termination factor NusA YP_002956786.1 PFAM: Protein of unknown function (DUF448) YP_002956787.1 PFAM: Elongation factor Tu GTP binding domain; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu domain 2; TIGRFAM: translation initiation factor IF-2; small GTP-binding protein domain YP_002956788.1 PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_002956789.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002956792.1 PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: cytidyltransferase-related domain; riboflavin kinase/FMN adenylyltransferase YP_002956793.1 PFAM: Methyltransferase domain YP_002956794.1 PFAM: CAAX amino terminal protease family YP_002956795.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002956796.1 PFAM: Polyribonucleotide nucleotidyltransferase, RNA binding domain; 3' exoribonuclease family, domain 1; KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 2; TIGRFAM: guanosine pentaphosphate synthetase I/polynucleotide phosphorylase YP_002956797.1 PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_002956798.1 PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_002956801.1 PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase YP_002956802.1 PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_002956803.1 PFAM: FtsK/SpoIIIE family; Ftsk gamma domain YP_002956804.1 PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002956805.1 PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain YP_002956807.1 PFAM: Helix-turn-helix YP_002956809.1 PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_002956810.1 PFAM: RecX family YP_002956811.1 PFAM: Uncharacterized protein family UPF0004; Radical SAM superfamily; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family YP_002956812.1 PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA) YP_002956813.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002956814.1 PFAM: Methyltransferase small domain YP_002956815.1 PFAM: FAD dependent oxidoreductase; Flavin-binding monooxygenase-like YP_002956816.1 PFAM: GTPase of unknown function; TIGRFAM: GTP-binding proten HflX; small GTP-binding protein domain YP_002956817.1 PFAM: DEAD/DEAH box helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_002956818.1 PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_002956819.1 PFAM: LexA DNA binding domain; Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_002956821.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002956822.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_002956823.1 PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_002956825.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis YP_002956829.1 PFAM: MarR family YP_002956830.1 PFAM: NADPH-dependent FMN reductase YP_002956831.1 PFAM: Luciferase-like monooxygenase YP_002956833.1 PFAM: Major Facilitator Superfamily YP_002956835.1 PFAM: FtsK/SpoIIIE family YP_002956836.1 PFAM: Type II/IV secretion system protein YP_002956837.1 PFAM: Bacterial type II secretion system protein F domain YP_002956838.1 PFAM: Bacterial type II secretion system protein F domain YP_002956840.1 PFAM: TadE-like protein YP_002956844.1 PFAM: RF-1 domain; PCRF domain; TIGRFAM: peptide chain release factor 2 YP_002956845.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_002956846.1 PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_002956847.1 PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, A subunit YP_002956848.1 PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit YP_002956849.1 PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_002956850.1 PFAM: CrcB-like protein YP_002956851.1 PFAM: CrcB-like protein YP_002956852.1 PFAM: Inositol monophosphatase family; TIGRFAM: histidinol-phosphate phosphatase HisN, inositol monophosphatase family YP_002956853.1 PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A YP_002956854.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002956855.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma-70 factor, TIGR02947 family; RNA polymerase sigma factor, sigma-70 family YP_002956856.1 TIGRFAM: anti-sigma factor, TIGR02949 family YP_002956858.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth YP_002956859.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002956860.1 PFAM: CBS domain pair; Domain of unknown function DUF21; Transporter associated domain YP_002956861.1 PFAM: Domain of unknown function DUF21; CBS domain pair YP_002956862.1 PFAM: Periplasmic solute binding protein family YP_002956863.1 PFAM: ABC 3 transport family YP_002956864.1 PFAM: ABC transporter YP_002956865.1 PFAM: Ferric uptake regulator family YP_002956866.1 PFAM: Rhodanese-like domain YP_002956867.1 PFAM: HIT domain YP_002956868.1 PFAM: Domain of unknown function (DUF1605); Helicase conserved C-terminal domain; Helicase associated domain (HA2); TIGRFAM: ATP-dependent helicase HrpA YP_002956869.1 PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter YP_002956870.1 PFAM: Aldehyde dehydrogenase family YP_002956871.1 PFAM: Methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase I YP_002956872.1 PFAM: ABC transporter YP_002956875.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002956877.1 PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_002956878.1 PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_002956879.1 PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO YP_002956880.1 PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_002956881.1 PFAM: Thiazole biosynthesis protein ThiG YP_002956882.1 PFAM: ThiF family; MoeZ/MoeB domain YP_002956883.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002956884.1 PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_002956885.1 PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain YP_002956886.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002956887.1 PFAM: GHMP kinases N terminal domain YP_002956888.1 PFAM: GHMP kinases C terminal YP_002956889.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002956890.1 PFAM: RF-1 domain; PCRF domain; TIGRFAM: peptide chain release factor 1 YP_002956891.1 PFAM: Methyltransferase small domain; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; HemK family methylases YP_002956892.1 PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_002956893.1 PFAM: Glycosyl transferase family 4 YP_002956895.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002956896.1 PFAM: ATP synthase subunit C YP_002956897.1 PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_002956898.1 PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 delta subunit YP_002956899.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002956900.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002956901.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002956902.1 PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain YP_002956904.1 PFAM: Protein of unknown function DUF91 YP_002956906.1 PFAM: Domain of unknown function DUF20 YP_002956908.1 PFAM: ABC transporter YP_002956911.1 PFAM: Type III restriction enzyme, res subunit YP_002956912.1 PFAM: Acetyltransferase (GNAT) family YP_002956913.1 PFAM: Isochorismatase family YP_002956914.1 PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: nicotinate phosphoribosyltransferase YP_002956915.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS YP_002956916.1 PFAM: Domain of unknown function (DUF2017) YP_002956917.1 PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_002956919.1 PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; TIGRFAM: ribonuclease PH YP_002956920.1 PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_002956921.1 PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family YP_002956922.1 PFAM: ADP-ribosylglycohydrolase YP_002956923.1 PFAM: Calcineurin-like phosphoesterase; TIGRFAM: exonuclease SbcD YP_002956924.1 TIGRFAM: exonuclease SbcC YP_002956925.1 PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium) YP_002956926.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002956927.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_002956928.1 PFAM: AhpC/TSA family YP_002956930.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002956932.1 PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_002956933.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate YP_002956934.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002956935.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002956936.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002956938.1 PFAM: tRNA synthetases class I (M); TIGRFAM: methionyl-tRNA synthetase YP_002956939.1 PFAM: Isocitrate/isopropylmalate dehydrogenase YP_002956940.1 PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II YP_002956941.1 PFAM: Carbon starvation protein CstA YP_002956942.1 PFAM: Protein of unknown function (DUF466) YP_002956943.1 PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family YP_002956944.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002956945.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_002956947.1 PFAM: GTPase of unknown function YP_002956948.1 PFAM: AIR synthase related protein, N-terminal domain; TIGRFAM: thiamine-monophosphate kinase YP_002956949.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_002956950.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_002956951.1 PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit YP_002956952.1 PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_002956953.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002956954.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_002956955.1 PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NADP oxidoreductase coenzyme F420-dependent YP_002956956.1 PFAM: ATP-grasp domain; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_002956958.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_002956959.1 PFAM: DAK2 domain YP_002956960.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain; TIGRFAM: ATP-dependent DNA helicase RecG YP_002956961.1 PFAM: Methyltransferase small domain; TIGRFAM: methyltransferase YP_002956962.1 PFAM: Aminotransferase class I and II YP_002956963.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002956964.1 PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase YP_002956965.1 PFAM: Uncharacterized ACR, COG1399 YP_002956966.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002956967.1 PFAM: Double-stranded RNA binding motif; RNase3 domain; TIGRFAM: ribonuclease III, bacterial YP_002956968.1 PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg) YP_002956969.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_002956970.1 PFAM: Glycosyl transferases group 1 YP_002956972.1 PFAM: Glycosyl transferases group 1 YP_002956973.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; TIGRFAM: nucleotide sugar dehydrogenase YP_002956974.1 PFAM: Glycosyl transferases group 1 YP_002956975.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; TIGRFAM: nucleotide sugar dehydrogenase YP_002956976.1 PFAM: Bacterial transferase hexapeptide (three repeats) YP_002956977.1 PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold YP_002956978.1 PFAM: Glycosyl transferases group 1 YP_002956980.1 PFAM: Glycosyl transferases group 1 YP_002956982.1 PFAM: ABC transporter YP_002956983.1 PFAM: ABC-2 type transporter YP_002956984.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_002956985.1 PFAM: Major Facilitator Superfamily YP_002956986.1 PFAM: Transposase YP_002956987.1 PFAM: SRP54-type protein, helical bundle domain; SRP54-type protein, GTPase domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_002956988.1 PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter YP_002956989.1 PFAM: SRP54-type protein, helical bundle domain; Signal peptide binding domain; SRP54-type protein, GTPase domain; TIGRFAM: signal recognition particle protein YP_002956990.1 PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_002956992.1 PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_002956993.1 PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_002956994.1 PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_002956995.1 PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_002956996.1 PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_002956997.1 PFAM: Ribonuclease HII YP_002956998.1 PFAM: Protein of unknown function (DUF2469) YP_002956999.1 PFAM: Uncharacterised protein family UPF0102 YP_002957000.1 PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein YP_002957001.1 PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_002957002.1 PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family YP_002957004.1 PFAM: Beta-ketoacyl synthase, C-terminal domain; Beta-ketoacyl synthase, N-terminal domain; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2 YP_002957005.1 carries the fatty acid chain in fatty acid biosynthesis YP_002957006.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002957007.1 PFAM: Acyl transferase domain YP_002957009.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002957011.1 PFAM: AhpC/TSA family YP_002957012.1 PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC YP_002957013.1 PFAM: Branched-chain amino acid transport protein (AzlD) YP_002957016.1 PFAM: Polyphosphate kinase 2 YP_002957017.1 PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating YP_002957018.1 PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase YP_002957019.1 PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteine synthase A YP_002957020.1 PFAM: Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase YP_002957021.1 PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486 YP_002957022.1 PFAM: zinc ribbon domain YP_002957023.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; RNase H YP_002957024.1 PFAM: Protein of unknown function (DUF328) YP_002957026.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_002957027.1 PFAM: Dihydrodipicolinate synthetase family YP_002957028.1 PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_002957029.1 PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_002957030.1 PFAM: Heavy-metal-associated domain YP_002957031.1 PFAM: haloacid dehalogenase-like hydrolase; E1-E2 ATPase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_002957032.1 PFAM: Antibiotic biosynthesis monooxygenase YP_002957035.1 PFAM: Phage protein Gp37/Gp68 YP_002957036.1 PFAM: Domain of unknown function (DUF955) YP_002957039.1 PFAM: Phage integrase family YP_002957040.1 PFAM: Exonuclease YP_002957044.1 PFAM: membrane protein (DUF2079) YP_002957045.1 PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_002957046.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_002957047.1 PFAM: Acyl-CoA thioesterase; TIGRFAM: acyl-CoA thioesterase II YP_002957049.1 PFAM: OsmC-like protein; Bacterial-like globin YP_002957051.1 PFAM: Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type YP_002957052.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_002957053.1 PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain YP_002957054.1 PFAM: Protein of unknown function (DUF1345) YP_002957055.1 PFAM: short chain dehydrogenase YP_002957056.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002957057.1 PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_002957058.1 PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_002957059.1 PFAM: ClpX C4-type zinc finger; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_002957060.1 PFAM: DSBA-like thioredoxin domain YP_002957062.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002957063.1 PFAM: short chain dehydrogenase YP_002957064.1 PFAM: CbiX YP_002957065.1 PFAM: Nitrite/Sulfite reductase ferredoxin-like half domain; Nitrite and sulphite reductase 4Fe-4S domain YP_002957066.1 PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: phosophoadenylyl-sulfate reductase (thioredoxin) YP_002957067.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002957068.1 PFAM: Elongation factor Tu GTP binding domain; TIGRFAM: sulfate adenylyltransferase, large subunit; small GTP-binding protein domain YP_002957069.1 PFAM: ABC transporter YP_002957070.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002957071.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase, N-terminal domain YP_002957072.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_002957073.1 TIGRFAM: conserved hypothetical protein TIGR03085; uncharacterized Actinobacterial protein TIGR03083 YP_002957074.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_002957075.1 PFAM: Mur ligase middle domain; Mur ligase family, glutamate ligase domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_002957077.1 PFAM: Nucleoside diphosphate kinase YP_002957078.1 PFAM: Vitamin K epoxide reductase family YP_002957079.1 PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family YP_002957080.1 PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_002957081.1 PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_002957082.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002957083.1 PFAM: Amino acid kinase family; PUA domain; TIGRFAM: glutamate 5-kinase YP_002957084.1 TIGRFAM: gamma-glutamyl phosphate reductase YP_002957086.1 PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain YP_002957087.1 PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-related protein YP_002957088.1 PFAM: Phosphoglycerate mutase family YP_002957089.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_002957090.1 PFAM: Transposase YP_002957091.1 PFAM: Transposase YP_002957093.1 PFAM: Transposase, Mutator family YP_002957094.1 PFAM: Integrase core domain YP_002957095.1 PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain YP_002957097.1 PFAM: Bacterial regulatory proteins, tetR family; Tetracyclin repressor, C-terminal all-alpha domain YP_002957098.1 PFAM: Flavin containing amine oxidoreductase YP_002957099.1 PFAM: Amino acid permease YP_002957100.1 PFAM: Aldehyde dehydrogenase family YP_002957102.1 PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type YP_002957103.1 PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_002957104.1 PFAM: Sortase family YP_002957109.1 PFAM: Transposase, Mutator family YP_002957110.1 PFAM: Transposase, Mutator family YP_002957111.1 PFAM: Domain of unknown function (DUF1931) YP_002957112.1 PFAM: Transposase, Mutator family YP_002957113.1 PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein NrdH YP_002957114.1 PFAM: NrdI Flavodoxin like; TIGRFAM: ribonucleoside-diphosphate reductase 2, operon protein nrdI YP_002957115.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002957116.1 PFAM: Ribonucleotide reductase, small chain YP_002957117.1 PFAM: NIL domain; ABC transporter YP_002957118.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002957119.1 PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Tat (twin-arginine translocation) pathway signal sequence YP_002957123.1 PFAM: Metallo-beta-lactamase superfamily YP_002957124.1 PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase YP_002957126.1 PFAM: Uncharacterised ACR, COG2135 YP_002957132.1 PFAM: Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; PHP domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_002957133.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_002957134.1 PFAM: HIT domain YP_002957135.1 PFAM: CDP-alcohol phosphatidyltransferase YP_002957136.1 PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein YP_002957137.1 PFAM: Fe-S metabolism associated domain YP_002957138.1 PFAM: Rhodanese-like domain YP_002957139.1 PFAM: AFG1-like ATPase YP_002957141.1 PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_002957142.1 PFAM: Formyl transferase, C-terminal domain; Formyl transferase; TIGRFAM: methionyl-tRNA formyltransferase YP_002957143.1 PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB YP_002957144.1 PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase YP_002957145.1 PFAM: Nicotinamide mononucleotide transporter; TIGRFAM: nicotinamide mononucleotide transporter PnuC YP_002957146.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD YP_002957147.1 PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit YP_002957148.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002957149.1 PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_002957150.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_002957151.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002957152.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002957153.1 PFAM: Phosphoribosyl-AMP cyclohydrolase YP_002957154.1 PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: anthranilate synthase component I, non-proteobacterial lineages YP_002957155.1 PFAM: Tryptophan-associated transmembrane protein (Trp_oprn_chp); TIGRFAM: trp region conserved hypothetical membrane protein YP_002957157.1 PFAM: Indole-3-glycerol phosphate synthase YP_002957158.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002957159.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002957160.1 PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_002957161.1 PFAM: Glutamate synthase central domain; Conserved region in glutamate synthase; Glutamine amidotransferases class-II; GXGXG motif YP_002957162.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit YP_002957163.1 PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase YP_002957164.1 PFAM: ANTAR domain; Response regulator receiver domain YP_002957165.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_002957166.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_002957167.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_002957168.1 PFAM: Na+/H+ ion antiporter subunit YP_002957169.1 PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF) YP_002957170.1 PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit YP_002957171.1 PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_002957172.1 PFAM: 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I YP_002957174.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002957175.1 PFAM: Methyltransferase small domain YP_002957176.1 PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: conserved hypothetical protein TIGR00257 YP_002957177.1 PFAM: Dephospho-CoA kinase; BCCT family transporter; TIGRFAM: dephospho-CoA kinase; choline/carnitine/betaine transport YP_002957178.1 PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase YP_002957179.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002957182.1 PFAM: Integral membrane protein TerC family YP_002957183.1 PFAM: Integral membrane protein TerC family YP_002957184.1 PFAM: alpha/beta hydrolase fold YP_002957185.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain YP_002957186.1 PFAM: Methyltransferase domain YP_002957187.1 PFAM: Metallo-beta-lactamase superfamily YP_002957188.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002957189.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_002957190.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002957191.1 PFAM: P-loop ATPase protein family YP_002957192.1 PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related YP_002957193.1 PFAM: Sporulation Regulator WhiA C terminal domain; Sporulation Regulator WhiA N terminal; TIGRFAM: conserved hypothetical protein YP_002957194.1 PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain YP_002957195.1 PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_002957196.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002957197.1 PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_002957198.1 PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_002957199.1 PFAM: Glucose-6-phosphate dehydrogenase subunit; TIGRFAM: opcA protein YP_002957200.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002957201.1 PFAM: Phosphoglucose isomerase YP_002957202.1 PFAM: Transaldolase; TIGRFAM: transaldolase, mycobacterial type YP_002957203.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002957204.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002957205.1 PFAM: Cytochrome oxidase assembly protein YP_002957206.1 PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_002957207.1 PFAM: ABC transporter YP_002957208.1 PFAM: LexA DNA binding domain YP_002957209.1 PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB YP_002957210.1 PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1 YP_002957211.1 PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_002957212.1 PFAM: Domain of unknown function DUF59 YP_002957213.1 PFAM: neutral zinc metallopeptidase YP_002957214.1 PFAM: ABC transporter YP_002957218.1 PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_002957219.1 PFAM: short chain dehydrogenase YP_002957220.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: phosphoserine phosphatase SerB; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like YP_002957221.1 PFAM: ABC transporter YP_002957222.1 PFAM: Domain of unknown function DUF81 YP_002957223.1 PFAM: SpoU rRNA Methylase family YP_002957224.1 PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_002957225.1 PFAM: Biotin/lipoate A/B protein ligase family YP_002957227.1 PFAM: Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type YP_002957228.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002957229.1 PFAM: Glycosyl transferases group 1; TIGRFAM: glycogen synthase, Corynebacterium family YP_002957230.1 PFAM: Acyl-CoA oxidase; Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_002957231.1 PFAM: Bacterial regulatory proteins, tetR family YP_002957232.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002957233.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002957234.1 PFAM: MaoC like domain YP_002957235.1 PFAM: Glycosyl transferases group 1; 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_002957236.1 PFAM: Peptidase family M20/M25/M40 YP_002957239.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002957240.1 PFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase; cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase YP_002957241.1 PFAM: Protein of unknown function DUF75 YP_002957242.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_002957243.1 PFAM: Peptidase family M50 YP_002957244.1 PFAM: tRNA methyltransferase complex GCD14 subunit YP_002957245.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_002957246.1 PFAM: proteasome component; Actinomycetales protein of unknown function, DUF275 YP_002957247.1 PFAM: Formiminotransferase-cyclodeaminase YP_002957248.1 PFAM: Transposase YP_002957250.1 PFAM: Protein of unknown function (DUF797) YP_002957251.1 PFAM: proteasome component; Actinomycetales protein of unknown function, DUF275 YP_002957252.1 PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_002957253.1 PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_002957255.1 PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_002957256.1 PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_002957257.1 PFAM: DSHCT (NUC185) domain; DEAD/DEAH box helicase; Helicase conserved C-terminal domain YP_002957259.1 PFAM: Glycosyl transferase family 2 YP_002957261.1 PFAM: SPFH domain / Band 7 family YP_002957262.1 PFAM: NfeD-like YP_002957263.1 PFAM: NADH:flavin oxidoreductase / NADH oxidase family; Pyridine nucleotide-disulphide oxidoreductase YP_002957267.1 PFAM: Transposase, Mutator family YP_002957269.1 PFAM: AsnC family YP_002957270.1 PFAM: Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_002957271.1 PFAM: Cytochrome c oxidase subunit III YP_002957272.1 PFAM: Cytochrome c YP_002957273.1 PFAM: Rieske [2Fe-2S] domain YP_002957274.1 PFAM: Cytochrome b(N-terminal)/b6/petB YP_002957275.1 PFAM: Transposase IS116/IS110/IS902 family; Transposase YP_002957276.1 PFAM: Transposase, Mutator family YP_002957277.1 PFAM: Integrase core domain YP_002957278.1 PFAM: IstB-like ATP binding protein YP_002957280.1 PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, subunit I YP_002957281.1 PFAM: Cytochrome C oxidase subunit II, periplasmic domain; TIGRFAM: cytochrome c oxidase, subunit II YP_002957282.1 PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein YP_002957283.1 PFAM: Peptidase family M20/M25/M40 YP_002957285.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_002957286.1 PFAM: alpha/beta hydrolase fold YP_002957287.1 PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_002957288.1 PFAM: Recombination protein O; TIGRFAM: DNA repair protein RecO YP_002957289.1 PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase, yeast type YP_002957290.1 PFAM: GTPase of unknown function; KH domain; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain; GTP-binding conserved hypothetical protein YP_002957291.1 PFAM: Domain of unknown function DUF21; CBS domain pair; Transporter associated domain YP_002957292.1 PFAM: Uncharacterized protein family UPF0054; TIGRFAM: conserved hypothetical protein TIGR00043 YP_002957293.1 PFAM: PhoH-like protein YP_002957294.1 PFAM: RNA methyltransferase; TIGRFAM: conserved hypothetical protein TIGR00046 YP_002957295.1 PFAM: DnaJ central domain (4 repeats); DnaJ domain; DnaJ C terminal region; TIGRFAM: chaperone protein DnaJ YP_002957296.1 PFAM: DeoR-like helix-turn-helix domain; HrcA protein C terminal domain; TIGRFAM: heat shock gene repressor HrcA YP_002957299.1 PFAM: HemN C-terminal region; Radical SAM superfamily; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase YP_002957300.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002957302.1 PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_002957303.1 PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_002957304.1 PFAM: Metallo-beta-lactamase superfamily; Competence protein; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2 YP_002957305.1 PFAM: Helix-hairpin-helix motif; SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein YP_002957306.1 PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: degV family protein YP_002957307.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002957309.1 PFAM: alpha/beta hydrolase fold YP_002957310.1 TIGRFAM: primosomal protein N' YP_002957311.1 PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, N-terminal domain; S-adenosylmethionine synthetase, central domain; TIGRFAM: S-adenosylmethionine synthetase YP_002957312.1 PFAM: Flavoprotein; DNA / pantothenate metabolism flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_002957313.1 PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_002957314.1 PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_002957316.1 PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2 YP_002957317.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002957318.1 PFAM: Glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain, CPSase domain; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_002957320.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002957321.1 PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_002957322.1 PFAM: Phosphoribosyl transferase domain YP_002957323.1 PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_002957324.1 PFAM: Elongation factor P (EF-P) OB domain; Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; TIGRFAM: translation elongation factor P YP_002957325.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002957326.1 PFAM: Shikimate kinase YP_002957327.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002957328.1 PFAM: Shikimate dehydrogenase substrate binding domain YP_002957329.1 PFAM: Aminodeoxychorismate lyase YP_002957330.1 PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: conserved hypothetical protein TIGR00250 YP_002957331.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002957334.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002957335.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_002957336.1 PFAM: Protein of unknown function (DUF1697) YP_002957337.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002957338.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002957339.1 PFAM: Amino acid permease YP_002957340.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002957341.1 PFAM: Domain of Unknown Function (DUF349) YP_002957343.1 PFAM: Region found in RelA / SpoT proteins; HD domain; ACT domain; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_002957344.1 PFAM: Protein export membrane protein; TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family YP_002957345.1 TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family YP_002957346.1 PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit YP_002957347.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002957348.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002957349.1 PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_002957350.1 PFAM: Domain of unknown function DUF28; TIGRFAM: conserved hypothetical protein TIGR01033 YP_002957351.1 PFAM: Peptidase family M3 YP_002957353.1 PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase YP_002957355.1 PFAM: HRDC domain; 3'-5' exonuclease; TIGRFAM: ribonuclease D YP_002957356.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_002957358.1 PFAM: Rieske [2Fe-2S] domain YP_002957360.1 PFAM: Aldo/keto reductase family YP_002957362.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002957363.1 PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1 YP_002957364.1 PFAM: TRAM domain YP_002957366.1 PFAM: TrkA-N domain; TrkA-C domain YP_002957367.1 PFAM: TrkA-N domain; TrkA-C domain YP_002957371.1 PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) YP_002957375.1 PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase YP_002957377.1 PFAM: CoA binding domain; Acetyltransferase (GNAT) family YP_002957378.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002957379.1 PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC YP_002957380.1 PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB) YP_002957381.1 PFAM: Bacterial Cytochrome Ubiquinol Oxidase YP_002957382.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002957383.1 PFAM: alpha/beta hydrolase fold; AMP-binding enzyme YP_002957384.1 PFAM: NAD dependent epimerase/dehydratase family YP_002957385.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002957387.1 PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain YP_002957389.1 PFAM: Protein of unknown function DUF75 YP_002957390.1 PFAM: Cytosol aminopeptidase family, N-terminal domain; Cytosol aminopeptidase family, catalytic domain YP_002957391.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002957392.1 PFAM: e3 binding domain; Biotin-requiring enzyme; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component) YP_002957394.1 PFAM: Protein kinase domain YP_002957395.1 PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B YP_002957396.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002957398.1 PFAM: RDD family YP_002957399.1 PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I YP_002957400.1 PFAM: Luciferase-like monooxygenase YP_002957401.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_002957402.1 PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I YP_002957403.1 PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002957405.1 PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_002957406.1 PFAM: ROK family YP_002957407.1 PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR YP_002957408.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002957409.1 PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_002957410.1 PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_002957411.1 PFAM: DivIVA protein YP_002957412.1 PFAM: YGGT family YP_002957413.1 PFAM: Protein of unknown function (DUF552) YP_002957414.1 PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_002957415.1 PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726 YP_002957416.1 PFAM: Tubulin/FtsZ family, C-terminal domain; Tubulin/FtsZ family, GTPase domain; TIGRFAM: cell division protein FtsZ YP_002957417.1 PFAM: POTRA domain, FtsQ-type YP_002957418.1 PFAM: Mur ligase middle domain; Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase YP_002957419.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002957420.1 PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW YP_002957421.1 PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_002957422.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002957423.1 PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; Mur ligase family, catalytic domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_002957424.1 PFAM: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetases YP_002957425.1 PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain YP_002957427.1 PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW YP_002957428.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002957430.1 PFAM: impB/mucB/samB family YP_002957431.1 PFAM: Polyprenyl synthetase YP_002957433.1 PFAM: LysM domain; Transglycosylase SLT domain YP_002957434.1 PFAM: Protein kinase domain; PASTA domain YP_002957435.1 PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II YP_002957436.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_002957438.1 PFAM: AMP-binding enzyme YP_002957439.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: mycothione reductase YP_002957440.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_002957442.1 PFAM: Uncharacterised ACR, COG1259 YP_002957443.1 PFAM: MerR family regulatory protein YP_002957444.1 PFAM: FHA domain YP_002957445.1 PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein YP_002957446.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase YP_002957447.1 PFAM: Transposase DDE domain YP_002957449.1 PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_002957450.1 PFAM: Bacterial regulatory protein, arsR family YP_002957453.1 PFAM: Transposase YP_002957455.1 PFAM: Transposase, Mutator family YP_002957456.1 PFAM: Integrase core domain YP_002957458.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002957459.1 PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase YP_002957460.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_002957461.1 PFAM: S4 domain; RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase family YP_002957462.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_002957463.1 PFAM: Sodium:dicarboxylate symporter family YP_002957464.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002957465.1 PFAM: Response regulator receiver domain YP_002957466.1 PFAM: AMP-binding enzyme YP_002957467.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_002957468.1 PFAM: MmgE/PrpD family YP_002957469.1 PFAM: Isocitrate lyase family; TIGRFAM: methylisocitrate lyase YP_002957470.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_002957471.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002957472.1 PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: tyrosine recombinase XerD YP_002957473.1 PFAM: NUDIX domain YP_002957474.1 PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_002957475.1 PFAM: ATP-NAD kinase YP_002957476.1 PFAM: Methyltransferase domain; S4 domain; TIGRFAM: hemolysin TlyA family protein YP_002957477.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily Class (subfamily) IIA; HAD-superfamily subfamily IIA hydrolase, TIGR01457 YP_002957478.1 PFAM: Integrase core domain YP_002957479.1 PFAM: Transposase YP_002957480.1 PFAM: S4 domain; tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_002957481.1 PFAM: UvrD/REP helicase YP_002957482.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002957483.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_002957484.1 PFAM: Transposase YP_002957485.1 PFAM: Transglycosylase-like domain; LysM domain YP_002957486.1 PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_002957487.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_002957488.1 PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases YP_002957489.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002957490.1 PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase YP_002957491.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_002957492.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_002957493.1 PFAM: AMP-binding enzyme; TIGRFAM: amino acid adenylation domain; non-ribosomal peptide synthetase terminal domain of unknown function YP_002957494.1 PFAM: Peptidase family M1 YP_002957495.1 PFAM: 4'-phosphopantetheinyl transferase superfamily YP_002957496.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002957497.1 PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_002957498.1 PFAM: CHY zinc finger YP_002957500.1 PFAM: Pyroglutamyl peptidase; TIGRFAM: pyroglutamyl-peptidase I YP_002957501.1 PFAM: Radical SAM superfamily YP_002957502.1 PFAM: NUDIX domain YP_002957503.1 PFAM: Major Facilitator Superfamily YP_002957505.1 PFAM: RNA 2'-O ribose methyltransferase substrate binding; SpoU rRNA Methylase family YP_002957506.1 PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_002957507.1 PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_002957508.1 PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_002957511.1 PFAM: Transcription factor WhiB YP_002957512.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Histidine kinase YP_002957514.1 PFAM: SAF domain YP_002957515.1 TIGRFAM: DNA binding domain, excisionase family YP_002957519.1 PFAM: SecA DEAD-like domain; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit YP_002957520.1 PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_002957521.1 PFAM: Phosphoribosyl transferase domain YP_002957523.1 PFAM: Transposase DDE domain YP_002957524.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; HAMP domain; His Kinase A (phosphoacceptor) domain YP_002957525.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_002957527.1 PFAM: Chorismate mutase type II; TIGRFAM: monofunctional chorismate mutase, alpha proteobacterial type YP_002957528.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002957529.1 PFAM: Aminotransferase class-V YP_002957530.1 PFAM: Transposase DDE domain YP_002957532.1 PFAM: TrkA-N domain; TrkA-C domain YP_002957533.1 PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_002957534.1 PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_002957535.1 PFAM: RibD C-terminal domain YP_002957536.1 PFAM: DnaJ domain YP_002957537.1 PFAM: SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, , group 2 YP_002957538.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2337); TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_002957539.1 PFAM: GlcNAc-PI de-N-acetylase YP_002957540.1 PFAM: Transposase DDE domain YP_002957542.1 PFAM: Domain of unknown function (DUF477) YP_002957543.1 PFAM: PspA/IM30 family YP_002957544.1 PFAM: Sodium/glutamate symporter YP_002957545.1 PFAM: Uncharacterised protein family (UPF0182) YP_002957546.1 PFAM: Transposase DDE domain YP_002957548.1 PFAM: PDZ domain (Also known as DHR or GLGF) YP_002957549.1 PFAM: Uncharacterised conserved protein (DUF2342) YP_002957550.1 PFAM: Protein of unknown function DUF45 YP_002957551.1 PFAM: ThiF family YP_002957552.1 PFAM: UvrD/REP helicase; HRDC domain YP_002957553.1 PFAM: NUDIX domain; NADH pyrophosphatase zinc ribbon domain YP_002957554.1 PFAM: Phosphotransferase enzyme family YP_002957555.1 PFAM: UvrD/REP helicase YP_002957556.1 PFAM: UvrD/REP helicase YP_002957557.1 PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain YP_002957558.1 3'-5' exonuclease of DNA polymerase III YP_002957559.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002957560.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002957561.1 PFAM: Branched-chain amino acid transport protein; TIGRFAM: branched-chain amino acid uptake carrier YP_002957562.1 PFAM: Protein of unknown function DUF88; TIGRFAM: conserved hypothetical protein TIGR00288 YP_002957564.1 PFAM: Uroporphyrinogen-III synthase HemD YP_002957565.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002957566.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002957567.1 PFAM: Chlorite dismutase YP_002957568.1 PFAM: Flavin containing amine oxidoreductase; TIGRFAM: protoporphyrinogen oxidase YP_002957569.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002957570.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002957571.1 PFAM: Bacterial regulatory proteins, tetR family YP_002957573.1 PFAM: RNB domain YP_002957574.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain YP_002957575.1 PFAM: PHP domain YP_002957576.1 PFAM: Aminopeptidase P, N-terminal domain; metallopeptidase family M24 YP_002957577.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002957579.1 PFAM: MgtE intracellular N domain; CBS domain pair YP_002957580.1 PFAM: Protein of unknown function (DUF1003) YP_002957581.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; Domain of unknown function DUF59 YP_002957582.1 TIGRFAM: twin arginine-targeting protein translocase TatB YP_002957584.1 PFAM: O-methyltransferase YP_002957587.1 PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 2; conserved hypothetical protein, DprA/Smf-related, family 1 YP_002957588.1 PFAM: ABC transporter YP_002957589.1 PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_002957590.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_002957591.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_002957592.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate YP_002957593.1 TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_002957595.1 PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type) YP_002957596.1 PFAM: Aminotransferase class I and II YP_002957597.1 PFAM: 4Fe-4S binding domain YP_002957599.1 PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; GTP-binding protein TypA/BipA YP_002957600.1 PFAM: Oligopeptide/dipeptide transporter, C-terminal region; ABC transporter; TIGRFAM: phosphonate C-P lyase system protein PhnK YP_002957601.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002957602.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002957603.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_002957604.1 PFAM: Flavin containing amine oxidoreductase YP_002957605.1 PFAM: ZIP Zinc transporter YP_002957606.1 PFAM: PDZ domain (Also known as DHR or GLGF); Trypsin YP_002957607.1 PFAM: Redoxin YP_002957608.1 PFAM: Patatin-like phospholipase YP_002957609.1 PFAM: Bacterial Transmembrane Pair family YP_002957610.1 PFAM: Ferritin-like domain YP_002957611.1 PFAM: Protein of unknown function (DUF808) YP_002957612.1 PFAM: alpha/beta hydrolase fold YP_002957614.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002957615.1 PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase YP_002957616.1 PFAM: Aminotransferase class-V YP_002957617.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system YP_002957618.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002957619.1 PFAM: ABC transporter YP_002957620.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002957621.1 PFAM: Sodium:dicarboxylate symporter family YP_002957622.1 PFAM: Sugar (and other) transporter; TIGRFAM: MFS transporter, sugar porter (SP) family YP_002957623.1 PFAM: DNA polymerase family A YP_002957624.1 PFAM: Major Facilitator Superfamily YP_002957625.1 PFAM: RF-1 domain YP_002957626.1 PFAM: Beta-lactamase; TIGRFAM: uncharacterized Actinobacterial protein TIGR03083 YP_002957627.1 PFAM: Domain of unknown function (DUF1794) YP_002957629.1 PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_002957630.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UbiD family decarboxylases YP_002957631.1 PFAM: ABC1 family; Phosphotransferase enzyme family YP_002957633.1 PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; TIGRFAM: succinate CoA transferases YP_002957635.1 PFAM: OsmC-like protein YP_002957636.1 PFAM: MarR family YP_002957637.1 PFAM: alpha/beta hydrolase fold YP_002957638.1 PFAM: Zinc-binding dehydrogenase YP_002957639.1 PFAM: DJ-1/PfpI family YP_002957640.1 PFAM: ABC transporter YP_002957641.1 PFAM: Patatin-like phospholipase YP_002957642.1 PFAM: Formate/nitrite transporter YP_002957643.1 PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_002957646.1 PFAM: Phosphoglycerate mutase family YP_002957649.1 PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: mismatch-specific thymine-DNA glycosylate (mug) YP_002957650.1 PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family YP_002957652.1 PFAM: Transposase, Mutator family YP_002957653.1 PFAM: Transposase, Mutator family YP_002957654.1 PFAM: Domain of unknown function (DUF323) YP_002957658.1 PFAM: Transposase YP_002957659.1 PFAM: Transposase, Mutator family YP_002957660.1 PFAM: Helix-turn-helix domain of resolvase; Resolvase, N terminal domain YP_002957662.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002957663.1 PFAM: Hsp20/alpha crystallin family YP_002957664.1 PFAM: ABC transporter YP_002957665.1 PFAM: ABC-2 type transporter YP_002957666.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002957667.1 PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_002957668.1 PFAM: Macro domain YP_002957670.1 PFAM: RmuC family YP_002957671.1 PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_002957672.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002957674.1 PFAM: OB-fold nucleic acid binding domain; Exonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit YP_002957675.1 PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit YP_002957676.1 PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family YP_002957677.1 PFAM: Polyphosphate kinase 2 YP_002957678.1 PFAM: Aminotransferase class I and II YP_002957680.1 PFAM: NUDIX domain YP_002957681.1 PFAM: Tetratricopeptide repeat YP_002957682.1 PFAM: Phosphotransferase enzyme family YP_002957684.1 PFAM: Acetyltransferase (GNAT) family YP_002957685.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_002957686.1 PFAM: regulatory protein (CxxC_CxxC_SSSS); TIGRFAM: regulatory protein, FmdB family YP_002957689.1 PFAM: NAD synthase; GMP synthase C terminal domain; Glutamine amidotransferase class-I; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit YP_002957692.1 PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein YP_002957693.1 PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_002957694.1 PFAM: Sodium:dicarboxylate symporter family YP_002957695.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_002957696.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_002957697.1 PFAM: Chaperonin 10 Kd subunit YP_002957699.1 PFAM: ABC transporter YP_002957700.1 PFAM: FecCD transport family YP_002957701.1 PFAM: FecCD transport family YP_002957702.1 PFAM: Periplasmic binding protein YP_002957704.1 PFAM: Glutamate-cysteine ligase family 2(GCS2); TIGRFAM: uncharacterized enzyme YP_002957705.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_002957706.1 PFAM: NAD dependent epimerase/dehydratase family YP_002957708.1 PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_002957710.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002957711.1 PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase YP_002957712.1 PFAM: Glycoprotease family YP_002957713.1 PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein YP_002957714.1 PFAM: Alanine racemase, N-terminal domain; Alanine racemase, C-terminal domain; TIGRFAM: alanine racemase YP_002957715.1 PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related YP_002957716.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002957718.1 PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glycogen debranching enzyme GlgX YP_002957719.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002957720.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002957721.1 PFAM: D-alanyl-D-alanine carboxypeptidase YP_002957722.1 PFAM: Large-conductance mechanosensitive channel, MscL; TIGRFAM: large conductance mechanosensitive channel protein YP_002957724.1 PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; TIGRFAM: phosphoglucosamine mutase YP_002957725.1 PFAM: N-acetylmuramoyl-L-alanine amidase YP_002957726.1 PFAM: Polyphosphate kinase 2 YP_002957727.1 forms a direct contact with the tRNA during translation YP_002957728.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002957729.1 PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_002957730.1 PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_002957731.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002957732.1 PFAM: Ribosomal protein S11 YP_002957733.1 PFAM: Ribosomal protein S13/S18 YP_002957734.1 PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_002957735.1 PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_002957736.1 PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_002957737.1 PFAM: Adenylate kinase; TIGRFAM: adenylate kinases YP_002957738.1 PFAM: eubacterial secY protein; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); preprotein translocase, SecY subunit YP_002957739.1 PFAM: Ribosomal protein L15; Ribosomal protein L15 amino terminal region; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_002957740.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002957741.1 PFAM: Ribosomal protein S5, N-terminal domain; Ribosomal protein S5, C-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_002957742.1 PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_002957743.1 PFAM: Ribosomal protein L6 YP_002957744.1 PFAM: Ribosomal protein S8 YP_002957745.1 PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5 YP_002957746.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002957747.1 PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_002957748.1 PFAM: Ribosomal protein S17 YP_002957749.1 PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_002957750.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002957751.1 PFAM: Ribosomal protein S3, N-terminal domain; Ribosomal protein S3, C-terminal domain; KH domain; TIGRFAM: ribosomal protein S3, bacterial type YP_002957752.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002957753.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002957754.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002957755.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002957756.1 PFAM: Ribosomal protein L4/L1 family YP_002957757.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002957758.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002957761.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002957762.1 PFAM: Elongation factor G C-terminus; Elongation factor G, domain IV; Elongation factor Tu GTP binding domain; Elongation factor Tu domain 2; TIGRFAM: small GTP-binding protein domain; translation elongation factor EF-G YP_002957763.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002957764.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002957765.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002957766.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002957767.1 PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_002957768.1 PFAM: Ribosomal protein L10 YP_002957769.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002957770.1 binds directly to 23S ribosomal RNA YP_002957771.1 PFAM: Transcription termination factor nusG; TIGRFAM: transcription termination/antitermination factor NusG YP_002957772.1 PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_002957773.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002957774.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_002957775.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PspC domain YP_002957776.1 PFAM: PspC domain YP_002957777.1 PFAM: Phosphofructokinase; TIGRFAM: phosphofructokinase YP_002957779.1 PFAM: Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ YP_002957780.1 PFAM: Domain of unknown function (DUF1794) YP_002957783.1 PFAM: Acetyltransferase (GNAT) family; TIGRFAM: mycothiol biosynthesis acetyltransferase YP_002957784.1 PFAM: Phosphoglycerate mutase family; NUDIX domain YP_002957786.1 PFAM: Thymidylate synthase; TIGRFAM: thymidylate synthase YP_002957787.1 PFAM: Dihydrofolate reductase YP_002957789.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002957790.1 PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_002957791.1 PFAM: MaoC like domain YP_002957794.1 PFAM: DEAD/DEAH box helicase; DbpA RNA binding domain; Helicase conserved C-terminal domain YP_002957796.1 PFAM: Amidohydrolase family YP_002957797.1 PFAM: Cys/Met metabolism PLP-dependent enzyme YP_002957798.1 PFAM: Pyridoxal-phosphate dependent enzyme; CBS domain pair; TIGRFAM: cystathionine beta-synthase YP_002957801.1 PFAM: AMP-binding enzyme YP_002957802.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002957804.1 PFAM: Bacterial protein of unknown function (DUF894) YP_002957805.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_002957806.1 PFAM: Integral membrane protein DUF6; TIGRFAM: rarD protein YP_002957808.1 PFAM: HIT domain YP_002957809.1 PFAM: Polyprenyl synthetase YP_002957810.1 PFAM: FAD binding domain; TIGRFAM: geranylgeranyl reductase family YP_002957811.1 PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; TIGRFAM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase YP_002957812.1 PFAM: Bacterial protein of unknown function (DUF839); TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_002957813.1 PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoic acid (OSB) synthetase YP_002957815.1 PFAM: PAP2 superfamily YP_002957816.1 PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Biotin-requiring enzyme; e3 binding domain YP_002957817.1 PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_002957818.1 PFAM: Dehydrogenase E1 component YP_002957819.1 PFAM: AsnC family YP_002957820.1 PFAM: Major Facilitator Superfamily YP_002957821.1 PFAM: Permease family YP_002957822.1 PFAM: Prolyl oligopeptidase family; Prolyl oligopeptidase, N-terminal beta-propeller domain YP_002957823.1 PFAM: Glycosyl hydrolases family 15 YP_002957824.1 PFAM: Glucose-6-phosphate dehydrogenase, C-terminal domain; Glucose-6-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase YP_002957825.1 PFAM: Enoyl-CoA hydratase/isomerase family; TIGRFAM: naphthoate synthase (dihydroxynaphthoic acid synthetase) YP_002957826.1 PFAM: Permease Membrane Region; TrkA-C domain; TIGRFAM: YidE/YbjL duplication YP_002957827.1 PFAM: AMP-binding enzyme YP_002957828.1 PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002957831.1 PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB YP_002957832.1 PFAM: ResB-like family YP_002957833.1 PFAM: Cytochrome C biogenesis protein transmembrane region YP_002957834.1 PFAM: Redoxin; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_002957835.1 PFAM: Phosphoglycerate mutase family YP_002957837.1 PFAM: Glutaredoxin-like domain (DUF836) YP_002957838.1 PFAM: Mitochondrial domain of unknown function (DUF1713) YP_002957839.1 PFAM: Histone deacetylase domain YP_002957840.1 PFAM: Cation transport protein YP_002957841.1 PFAM: TrkA-N domain; TrkA-C domain YP_002957842.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_002957843.1 PFAM: Xylose isomerase-like TIM barrel YP_002957844.1 PFAM: Ppx/GppA phosphatase family YP_002957845.1 PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_002957847.1 PFAM: Methyltransferase small domain YP_002957848.1 PFAM: Rhodanese-like domain YP_002957849.1 PFAM: Transposase YP_002957850.1 PFAM: Acetyltransferase (GNAT) family YP_002957851.1 PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Domain of unknown function (DUF1998) YP_002957855.1 PFAM: Bacterial type II secretion system protein F domain YP_002957856.1 PFAM: Type II/IV secretion system protein YP_002957857.1 PFAM: NUDIX domain YP_002957858.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_002957859.1 PFAM: Helix-hairpin-helix motif; Iron-sulfur binding domain of endonuclease III; TIGRFAM: endonuclease III YP_002957860.1 PFAM: AMP-binding enzyme; TIGRFAM: acetate--CoA ligase YP_002957861.1 PFAM: Bacterial regulatory proteins, gntR family YP_002957863.1 PFAM: Sodium:neurotransmitter symporter family YP_002957864.1 PFAM: Colicin V production protein; Trypsin YP_002957865.1 PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_002957867.1 PFAM: Endoribonuclease L-PSP YP_002957870.1 PFAM: Integrase core domain YP_002957871.1 PFAM: Multicopper oxidase; Multicopper oxidase; Multicopper oxidase; TIGRFAM: copper-resistance protein, CopA family YP_002957873.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_002957874.1 PFAM: His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002957875.1 PFAM: Heavy-metal-associated domain YP_002957876.1 PFAM: haloacid dehalogenase-like hydrolase; E1-E2 ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase YP_002957877.1 PFAM: Domain of unknown function (DUF305) YP_002957878.1 catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis YP_002957879.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis YP_002957880.1 PFAM: Domain of Unknown Function (DUF326) YP_002957882.1 PFAM: Transposase, Mutator family YP_002957883.1 PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase YP_002957884.1 PFAM: Calcineurin-like phosphoesterase YP_002957885.1 PFAM: ABC transporter; ABC transporter transmembrane region YP_002957886.1 PFAM: ABC transporter; ABC transporter transmembrane region YP_002957887.1 PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002957888.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002957890.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_002957891.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002957892.1 PFAM: permease YP_002957893.1 PFAM: ABC transporter YP_002957894.1 PFAM: L-asparaginase II YP_002957897.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002957898.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002957900.1 PFAM: Sir2 family YP_002957903.1 PFAM: ATPase family associated with various cellular activities (AAA); C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_002957904.1 PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_002957907.1 PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_002957908.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_002957909.1 PFAM: ABC transporter YP_002957911.1 PFAM: SNARE associated Golgi protein YP_002957913.1 PFAM: methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase YP_002957914.1 PFAM: Alpha/beta hydrolase of unknown function (DUF1023) YP_002957915.1 PFAM: MerR family regulatory protein YP_002957916.1 PFAM: DnaJ C terminal region; DnaJ domain YP_002957917.1 PFAM: GrpE YP_002957918.1 PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_002957919.1 PFAM: Ferritin-like domain YP_002957923.1 PFAM: MMPL family YP_002957924.1 PFAM: MarR family YP_002957927.1 PFAM: Aminotransferase class IV YP_002957929.1 PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit YP_002957932.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_002957933.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_002957934.1 PFAM: Domain related to MnhB subunit of Na+/H+ antiporter; NADH-Ubiquinone/plastoquinone (complex I), various chains YP_002957935.1 PFAM: Major Facilitator Superfamily YP_002957936.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002957937.1 PFAM: F420-0:Gamma-glutamyl ligase YP_002957938.1 PFAM: TrkA-C domain YP_002957939.1 PFAM: Sodium/hydrogen exchanger family YP_002957940.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2087) YP_002957941.1 PFAM: Membrane transport protein YP_002957942.1 TIGRFAM: diaminopimelate dehydrogenase YP_002957945.1 PFAM: NHL repeat; AhpC/TSA family YP_002957947.1 PFAM: Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Copper resistance protein D YP_002957948.1 PFAM: Dyp-type peroxidase family; TIGRFAM: Tat-translocated enzyme; Dyp-type peroxidase family YP_002957949.1 PFAM: Protein of unknown function (DUF461) YP_002957950.1 PFAM: Copper resistance protein CopC YP_002957952.1 PFAM: Bacterial DNA-binding protein YP_002957953.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002957954.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002957955.1 required for 70S ribosome assembly YP_002957956.1 PFAM: Integral membrane protein DUF125 YP_002957958.1 PFAM: Protein of unknown function (DUF1445) YP_002957959.1 PFAM: Bacterial regulatory proteins, gntR family YP_002957960.1 PFAM: Biotin-requiring enzyme; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin carboxylase C-terminal domain; ATP-grasp domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase YP_002957961.1 PFAM: Allophanate hydrolase subunit 1; Allophanate hydrolase subunit 2; TIGRFAM: conserved hypothetical protein TIGR00370; biotin-dependent carboxylase uncharacterized domain YP_002957962.1 PFAM: LamB/YcsF family YP_002957964.1 PFAM: Metallo-beta-lactamase superfamily YP_002957965.1 PFAM: Universal stress protein family YP_002957966.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002957967.1 PFAM: S4 domain YP_002957968.1 PFAM: ABC transporter YP_002957973.1 PFAM: Flavin reductase like domain YP_002957974.1 PFAM: 'Cold-shock' DNA-binding domain YP_002957975.1 PFAM: Major Facilitator Superfamily YP_002957976.1 PFAM: Conserved region in glutamate synthase YP_002957977.1 PFAM: Thioesterase superfamily YP_002957978.1 PFAM: Aldehyde dehydrogenase family; Proline dehydrogenase YP_002957979.1 PFAM: Porphyromonas-type peptidyl-arginine deiminase YP_002957980.1 PFAM: Domain of unknown function DUF20 YP_002957981.1 PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily YP_002957982.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002957983.1 PFAM: ABC transporter YP_002957984.1 PFAM: Bacterial regulatory proteins, tetR family YP_002957985.1 PFAM: RNase H YP_002957986.1 PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_002957989.1 PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_002957990.1 PFAM: AMP-binding enzyme YP_002957991.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_002957992.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_002957995.1 PFAM: Protein of unknown function DUF262; Protein of unknown function (DUF1524) YP_002957996.1 PFAM: MazG nucleotide pyrophosphohydrolase domain YP_002957997.1 PFAM: GIY-YIG catalytic domain; Uncharacterized conserved protein (DUF2075) YP_002958000.1 PFAM: Transposase YP_002958001.1 PFAM: PhoD-like phosphatase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_002958004.1 PFAM: Glycosyl transferase family 2 YP_002958007.1 PFAM: Glycosyl transferase family 2 YP_002958009.1 PFAM: Glycosyl transferases group 1 YP_002958012.1 PFAM: Uncharacterised ACR, YkgG family COG1556 YP_002958013.1 PFAM: Uncharacterised ACR, YkgG family COG1556; TIGRFAM: 2[4Fe-4S] protein YP_002958014.1 PFAM: Cysteine-rich domain YP_002958015.1 PFAM: L-lactate permease; TIGRFAM: L-lactate transport YP_002958016.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_002958017.1 PFAM: Protein of unknown function (DUF456) YP_002958018.1 PFAM: AsnC family YP_002958019.1 PFAM: Alanine dehydrogenase/PNT, N-terminal domain; Alanine dehydrogenase/PNT, C-terminal domain; TIGRFAM: alanine dehydrogenase YP_002958020.1 PFAM: SNO glutamine amidotransferase family YP_002958021.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_002958023.1 PFAM: HpcH/HpaI aldolase/citrate lyase family YP_002958025.1 PFAM: Aminotransferase class I and II YP_002958026.1 PFAM: Demethylmenaquinone methyltransferase; Fumarylacetoacetate (FAA) hydrolase family YP_002958027.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_002958028.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_002958029.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_002958030.1 PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_002958031.1 PFAM: HpcH/HpaI aldolase/citrate lyase family YP_002958033.1 PFAM: Uncharacterized ACR, YdiU/UPF0061 family YP_002958034.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_002958035.1 PFAM: Rieske [2Fe-2S] domain YP_002958036.1 PFAM: LysM domain; N-acetylmuramoyl-L-alanine amidase YP_002958037.1 PFAM: HPP family YP_002958038.1 PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_002958039.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_002958040.1 catalyzes the formation of catechol from phenol YP_002958043.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_002958044.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_002958045.1 PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit YP_002958046.1 PFAM: Domain of unknown function DUF59; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit YP_002958047.1 PFAM: Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit YP_002958048.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_002958049.1 PFAM: Sugar (and other) transporter YP_002958050.1 PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: beta-ketoadipyl CoA thiolase; acetyl-CoA acetyltransferases YP_002958051.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_002958052.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain YP_002958053.1 PFAM: Protein of unknown function (DUF419) YP_002958054.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_002958055.1 PFAM: Aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_002958057.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_002958058.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain YP_002958060.1 PFAM: Bacterial regulatory proteins, tetR family YP_002958061.1 PFAM: AMP-binding enzyme; TIGRFAM: phenylacetate-CoA ligase YP_002958062.1 PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD YP_002958064.1 PFAM: Transposase YP_002958065.1 PFAM: AMP-binding enzyme YP_002958066.1 PFAM: Acetyltransferase (GNAT) family YP_002958067.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002958069.1 PFAM: UPF0126 domain YP_002958070.1 PFAM: UPF0126 domain YP_002958071.1 PFAM: Domain of unknown function (DUF1846) YP_002958072.1 PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm) YP_002958074.1 PFAM: Transposase YP_002958075.1 PFAM: CoA-transferase family III YP_002958076.1 PFAM: Protein of unknown function (DUF664) YP_002958077.1 PFAM: haloacid dehalogenase-like hydrolase; E1-E2 ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_002958078.1 PFAM: Transposase, Mutator family YP_002958079.1 PFAM: Thioesterase superfamily YP_002958082.1 PFAM: Cobalt transport protein YP_002958083.1 PFAM: ABC transporter YP_002958084.1 PFAM: BioY family YP_002958085.1 PFAM: Transposase, Mutator family YP_002958086.1 PFAM: Bacterial regulatory protein, arsR family YP_002958087.1 PFAM: Sodium Bile acid symporter family; TIGRFAM: arsenical-resistance protein YP_002958088.1 PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_002958089.1 PFAM: FAD dependent oxidoreductase YP_002958090.1 PFAM: Bacterial regulatory protein, arsR family YP_002958091.1 PFAM: Cadmium resistance transporter YP_002958092.1 PFAM: Manganese containing catalase YP_002958094.1 PFAM: Phage integrase family YP_002958095.1 PFAM: Phage integrase family; Phage integrase, N-terminal SAM-like domain YP_002958097.1 PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein ( transcriptional regulator) YP_002958099.1 PFAM: Acetyltransferase (GNAT) family YP_002958100.1 PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; TIGRFAM: transcriptional regulator, ArgP family YP_002958101.1 PFAM: LysE type translocator; TIGRFAM: L-lysine exporter YP_002958102.1 PFAM: MerR family regulatory protein; TIGRFAM: DNA binding domain, excisionase family YP_002958104.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_002958105.1 PFAM: Domain of unknown function (DUF1852) YP_002958106.1 PFAM: Cys/Met metabolism PLP-dependent enzyme YP_002958107.1 PFAM: Cys/Met metabolism PLP-dependent enzyme YP_002958108.1 PFAM: Methyltransferase domain YP_002958109.1 PFAM: Major Facilitator Superfamily YP_002958110.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_002958111.1 PFAM: Acetyltransferase (GNAT) family YP_002958115.1 PFAM: Protein of unknown function (DUF805) YP_002958116.1 PFAM: Transposase YP_002958117.1 PFAM: Integrase core domain YP_002958118.1 PFAM: Transposase DDE domain YP_002958121.1 PFAM: Acetyltransferase (GNAT) family YP_002958125.1 PFAM: Methyltransferase domain YP_002958126.1 PFAM: NUDIX domain YP_002958127.1 PFAM: membrane protein (DUF2243) YP_002958128.1 PFAM: Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) YP_002958129.1 PFAM: MarR family YP_002958130.1 PFAM: OsmC-like protein YP_002958131.1 PFAM: Protein of unknown function (DUF805) YP_002958132.1 PFAM: GDSL-like Lipase/Acylhydrolase YP_002958136.1 PFAM: Aminotransferase class I and II YP_002958137.1 PFAM: SWIM zinc finger; SNF2 family N-terminal domain; Helicase conserved C-terminal domain YP_002958138.1 PFAM: NAD dependent epimerase/dehydratase family YP_002958139.1 PFAM: Glycosyl transferase family 2 YP_002958141.1 TIGRFAM: lycopene cyclase domain YP_002958142.1 TIGRFAM: lycopene cyclase domain YP_002958143.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_002958144.1 PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase YP_002958145.1 PFAM: Squalene/phytoene synthase YP_002958146.1 PFAM: Polyprenyl synthetase YP_002958148.1 PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1 YP_002958149.1 PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_002958150.1 PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II YP_002958151.1 PFAM: Pyridoxamine 5'-phosphate oxidase YP_002958152.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002958153.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2236) YP_002958155.1 PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases YP_002958156.1 PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_002958157.1 PFAM: Uncharacterised BCR, COG1937 YP_002958158.1 PFAM: Heavy-metal-associated domain YP_002958159.1 PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; Heavy-metal-associated domain; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; copper-(or silver)-translocating P-type ATPase YP_002958161.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_002958162.1 PFAM: Antibiotic biosynthesis monooxygenase YP_002958163.1 PFAM: Thioesterase superfamily; TIGRFAM: phenylacetic acid degradation protein PaaD; uncharacterized domain 1 YP_002958165.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_002958166.1 PFAM: Aldehyde dehydrogenase family YP_002958167.1 PFAM: GAF domain YP_002958168.1 PFAM: Protein of unknown function (DUF779) YP_002958169.1 PFAM: Acetyltransferase (GNAT) family YP_002958170.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, central domain YP_002958171.1 PFAM: Protein of unknown function (DUF1470) YP_002958172.1 PFAM: Integrase core domain YP_002958173.1 PFAM: lactate/malate dehydrogenase, NAD binding domain; lactate/malate dehydrogenase, alpha/beta C-terminal domain; TIGRFAM: L-lactate dehydrogenase YP_002958176.1 PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_002958177.1 PFAM: CAAX amino terminal protease family YP_002958179.1 PFAM: Sulfate transporter family; STAS domain YP_002958181.1 PFAM: permease YP_002958182.1 PFAM: ABC transporter YP_002958185.1 PFAM: ABC transporter; ABC transporter transmembrane region YP_002958186.1 PFAM: ABC transporter; ABC transporter transmembrane region YP_002958187.1 PFAM: Uncharacterised BCR, COG1937 YP_002958188.1 PFAM: Domain of unknown function DUF81 YP_002958189.1 PFAM: Rhodanese-like domain YP_002958190.1 PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain YP_002958191.1 PFAM: Phospholipase D Active site motif YP_002958192.1 PFAM: Thioesterase superfamily YP_002958193.1 PFAM: HEAT repeat YP_002958194.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_002958196.1 PFAM: Glycosyl hydrolase family 65 central catalytic domain; haloacid dehalogenase-like hydrolase; Glycosyl hydrolase family 65, N-terminal domain; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; beta-phosphoglucomutase family hydrolase YP_002958197.1 PFAM: Transposase; Transposase IS116/IS110/IS902 family YP_002958199.1 PFAM: ABC transporter YP_002958202.1 PFAM: Transposase DDE domain YP_002958204.1 PFAM: Bacterial membrane flanked domain YP_002958205.1 PFAM: Bacterial membrane flanked domain YP_002958206.1 PFAM: Histidine kinase YP_002958207.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_002958208.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002958210.1 PFAM: 2-nitropropane dioxygenase YP_002958211.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002958212.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_002958214.1 PFAM: Bacterial regulatory proteins, tetR family YP_002958215.1 PFAM: ABC transporter YP_002958217.1 PFAM: permease YP_002958218.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_002958219.1 PFAM: Sodium Bile acid symporter family; TIGRFAM: bile acid transporter YP_002958221.1 PFAM: ABC transporter; ABC transporter transmembrane region YP_002958222.1 PFAM: NUDIX domain YP_002958223.1 PFAM: LysE type translocator YP_002958224.1 PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: transcriptional regulator, ArgP family YP_002958226.1 PFAM: His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_002958228.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_002958229.1 PFAM: ubiE/COQ5 methyltransferase family; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases YP_002958230.1 PFAM: Periplasmic binding protein YP_002958231.1 PFAM: FecCD transport family YP_002958232.1 PFAM: FecCD transport family YP_002958233.1 PFAM: ABC transporter YP_002958234.1 PFAM: Siderophore-interacting protein; Siderophore-interacting FAD-binding domain YP_002958237.1 PFAM: Glutaminase YP_002958238.1 PFAM: Acetyltransferase (GNAT) family YP_002958240.1 PFAM: FAD linked oxidases, C-terminal domain; FAD binding domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_002958241.1 PFAM: Thioesterase superfamily; TIGRFAM: conserved hypothetical protein TIGR00051 YP_002958242.1 PFAM: Region found in RelA / SpoT proteins YP_002958243.1 PFAM: SNARE associated Golgi protein YP_002958245.1 TIGRFAM: uncharacterized Actinobacterial protein TIGR03083; conserved hypothetical protein TIGR03086 YP_002958246.1 PFAM: Polysaccharide deacetylase YP_002958247.1 PFAM: Transposase YP_002958248.1 TIGRFAM: conserved hypothetical protein YP_002958249.1 PFAM: Acetyltransferase (GNAT) family YP_002958250.1 PFAM: ABC-2 type transporter; TIGRFAM: X-X-X-Leu-X-X-Gly heptad repeats; YhgE/Pip C-terminal domain; YhgE/Pip N-terminal domain YP_002958252.1 PFAM: Bacterial regulatory proteins, tetR family YP_002958253.1 PFAM: Domain of unknown function DUF81 YP_002958254.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_002958255.1 PFAM: Peptidase family M23 YP_002958258.1 PFAM: Acetyltransferase (GNAT) family YP_002958262.1 PFAM: Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain YP_002958263.1 PFAM: Fatty acid desaturase YP_002958264.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002958265.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_002958266.1 PFAM: Bacterial extracellular solute-binding protein YP_002958267.1 PFAM: Bacterial regulatory proteins, lacI family; Periplasmic binding proteins and sugar binding domain of the LacI family YP_002958268.1 PFAM: TOBE domain; ABC transporter YP_002958269.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_002958272.1 PFAM: Acetyltransferase (GNAT) family YP_002958273.1 PFAM: Glutaredoxin YP_002958276.1 PFAM: DSBA-like thioredoxin domain YP_002958277.1 PFAM: Pterin 4 alpha carbinolamine dehydratase YP_002958279.1 PFAM: Major Facilitator Superfamily YP_002958280.1 PFAM: Alcohol dehydrogenase GroES-like domain YP_002958281.1 PFAM: DJ-1/PfpI family YP_002958283.1 PFAM: Rieske [2Fe-2S] domain; FAD dependent oxidoreductase YP_002958285.1 PFAM: short chain dehydrogenase YP_002958286.1 PFAM: Bacterial transcription activator, effector binding domain YP_002958287.1 PFAM: Phenazine biosynthesis-like protein; TIGRFAM: phenazine biosynthesis protein PhzF family YP_002958288.1 PFAM: Amidohydrolase family YP_002958289.1 catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine YP_002958290.1 PFAM: ABC transporter YP_002958293.1 PFAM: alpha/beta hydrolase fold YP_002958295.1 PFAM: Protein of unknown function (DUF664) YP_002958296.1 PFAM: MerR family regulatory protein YP_002958297.1 PFAM: YeeE/YedE family (DUF395) YP_002958298.1 PFAM: SirA-like protein YP_002958299.1 PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_002958300.1 PFAM: AMP-binding enzyme YP_002958302.1 PFAM: Polysaccharide deacetylase YP_002958303.1 PFAM: Asparaginase YP_002958305.1 PFAM: MerR family regulatory protein YP_002958306.1 PFAM: Acetyltransferase (GNAT) family YP_002958310.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2220) YP_002958311.1 PFAM: membrane-bound metal-dependent hydrolase (DUF457) YP_002958312.1 PFAM: LrgB-like family; TIGRFAM: conserved hypothetical protein TIGR00659 YP_002958313.1 PFAM: LrgA family YP_002958314.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_002958316.1 PFAM: Fic/DOC family YP_002958318.1 PFAM: Acetyltransferase (GNAT) family YP_002958321.1 PFAM: FAD dependent oxidoreductase YP_002958322.1 PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_002958323.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_002958329.1 PFAM: Transposase DDE domain YP_002958331.1 PFAM: AIPR protein YP_002958332.1 PFAM: DnaB-like helicase C terminal domain; DnaB-like helicase N terminal domain; TIGRFAM: replicative DNA helicase YP_002958333.1 PFAM: CoA-transferase family III YP_002958334.1 PFAM: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, C-terminal domain YP_002958335.1 PFAM: TrkA-C domain; RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family YP_002958336.1 PFAM: Protein of unknown function (DUF785) YP_002958337.1 PFAM: Succinylglutamate desuccinylase / Aspartoacylase family YP_002958338.1 PFAM: Major Facilitator Superfamily YP_002958340.1 PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_002958341.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002958342.1 PFAM: OB-fold nucleic acid binding domain; TIGRFAM: single stranded DNA-binding protein (ssb) YP_002958343.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002958344.1 catalyzes the removal of amino acids from the N termini of peptides YP_002958347.1 PFAM: Myo-inositol-1-phosphate synthase; TIGRFAM: inositol 1-phosphate synthase, Actinobacterial type YP_002958349.1 PFAM: Acyltransferase family YP_002958351.1 PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: tRNA adenylyltransferase; uncharacterized domain HDIG YP_002958352.1 PFAM: NUDIX domain YP_002958353.1 PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN YP_002958355.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_002958356.1 PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_002958357.1 PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_002958359.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_002958360.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002958361.1 PFAM: R3H domain YP_002958362.1 PFAM: 60Kd inner membrane protein YP_002958363.1 PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein TIGR00278 YP_002958364.1 PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_002958365.1 PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type