-- dump date 20120504_152752 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_005169477.1 378769744 11811400 1..1524 1 NC_016804.1 Differs from Rv0001 by 1aa, R156N ,and from Mb0001 by 1aa, V353I en BCG Pasteur, BCG Tokyo y BCG Mexico; chromosomal replication initiator protein DnaA 1524 dnaA 11811400 dnaA Mycobacterium bovis BCG str. Mexico chromosomal replication initiator protein DnaA YP_005169477.1 1 D 717522 CDS YP_005169478.1 378769745 11811433 2052..3260 1 NC_016804.1 DNA polymerase III subunit beta 3260 dnaN 11811433 dnaN Mycobacterium bovis BCG str. Mexico DNA polymerase III subunit beta YP_005169478.1 2052 D 717522 CDS YP_005169479.1 378769746 11811525 3280..4437 1 NC_016804.1 Differs from Rv0003 by 2aa, V158L, T245I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur,BCG Tokyo and BCG Mexico; DNA recombination and repair protein RecF 4437 recF 11811525 recF Mycobacterium bovis BCG str. Mexico DNA recombination and repair protein RecF YP_005169479.1 3280 D 717522 CDS YP_005169480.1 378769747 11812016 4434..4997 1 NC_016804.1 Differs from Mb0004 by 1aa, S16L in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4997 11812016 BCGMEX_0004 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169480.1 4434 D 717522 CDS YP_005169481.1 378769748 11812062 5123..7267 1 NC_016804.1 Differs from Rv0005 by 1aa, S442A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; DNA gyrase subunit B 7267 gyrB 11812062 gyrB Mycobacterium bovis BCG str. Mexico DNA gyrase subunit B YP_005169481.1 5123 D 717522 CDS YP_005169482.1 378769749 11812104 7302..9818 1 NC_016804.1 Differs from Mb0006 by 1aa, D639A, and from Rv0006 by 3aa, Q21E, T95S, D668G in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; DNA gyrase subunit A 9818 gyrA 11812104 gyrA Mycobacterium bovis BCG str. Mexico DNA gyrase subunit A YP_005169482.1 7302 D 717522 CDS YP_005169483.1 378769750 11812134 9914..10828 1 NC_016804.1 Differs from Mb0007 by 1aa, I272V in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 10828 11812134 BCGMEX_0007 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169483.1 9914 D 717522 CDS YP_005169484.1 378769751 11808271 complement(11874..12311) 1 NC_016804.1 Differs from Rv0008c by 1aa, P145S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 12311 11808271 BCGMEX_0008c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169484.1 11874 R 717522 CDS YP_005169485.1 378769752 11808272 12468..13016 1 NC_016804.1 peptidyl-prolyl cis-trans isomerase 13016 ppiA 11808272 ppiA Mycobacterium bovis BCG str. Mexico peptidyl-prolyl cis-trans isomerase YP_005169485.1 12468 D 717522 CDS YP_005169486.1 378769753 11808273 complement(13222..13557) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base deletion (g-*) leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (111 aa versus 141 aa); hypothetical protein 13557 11808273 BCGMEX_0010c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169486.1 13222 R 717522 CDS YP_005169487.1 378769754 11808274 complement(13713..13994) 1 NC_016804.1 hypothetical protein 13994 11808274 BCGMEX_0011c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169487.1 13713 R 717522 CDS YP_005169488.1 378769755 11808275 14088..14876 1 NC_016804.1 Differs from Rv0012 by 2aa, E105K, R233C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 14876 11808275 BCGMEX_0012 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169488.1 14088 D 717522 CDS YP_005169489.1 378769756 11808276 14913..15611 1 NC_016804.1 Differs from Rv0013 by 1aa, M68I in BCG Pasteur, BCG Tokyo and BCG Mexico; Para-aminobenzoate synthase, amidotransferase component 15611 trpG 11808276 trpG Mycobacterium bovis BCG str. Mexico Para-aminobenzoate synthase, amidotransferase component YP_005169489.1 14913 D 717522 CDS YP_005169490.1 378769757 11808277 complement(15589..17469) 1 NC_016804.1 Transmembrane serine/threonine-protein kinase B 17469 pknB 11808277 pknB Mycobacterium bovis BCG str. Mexico Transmembrane serine/threonine-protein kinase B YP_005169490.1 15589 R 717522 CDS YP_005169491.1 378769758 11808278 complement(17466..18761) 1 NC_016804.1 Serine/threonine protein kinase 18761 pknA 11808278 pknA Mycobacterium bovis BCG str. Mexico Serine/threonine protein kinase YP_005169491.1 17466 R 717522 CDS YP_005169492.1 378769759 11808279 complement(18758..20233) 1 NC_016804.1 penicillin-binding protein A 20233 pbpA 11808279 pbpA Mycobacterium bovis BCG str. Mexico penicillin-binding protein A YP_005169492.1 18758 R 717522 CDS YP_005169493.1 378769760 11808280 complement(20230..21639) 1 NC_016804.1 cell division protein FtsW 21639 rodA 11808280 rodA Mycobacterium bovis BCG str. Mexico cell division protein FtsW YP_005169493.1 20230 R 717522 CDS YP_005169494.1 378769761 11808281 complement(21636..23180) 1 NC_016804.1 Differs from Rv0018c by 3aa, L3R, A455S, S463P in Mcobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative protein phosphatase 23180 ppp 11808281 ppp Mycobacterium bovis BCG str. Mexico putative protein phosphatase YP_005169494.1 21636 R 717522 CDS YP_005169495.1 378769762 11808282 complement(23269..23736) 1 NC_016804.1 FHA-domain-containing protein 23736 11808282 BCGMEX_0019c Mycobacterium bovis BCG str. Mexico FHA-domain-containing protein YP_005169495.1 23269 R 717522 CDS YP_005169496.1 378769763 11808283 complement(23860..25425) 1 NC_016804.1 Differs from Mb0020c by 2aa, G47R, Y250H, and from Rv0020c by 3aa, G222D, C298Y, Q378R, and deletion of 6aa (EQRGYP) at position 246 in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 25425 11808283 BCGMEX_0020c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169496.1 23860 R 717522 CDS YP_005169497.1 378769764 11808285 complement(25894..26862) 1 NC_016804.1 Differs from Rv0021c by 1aa, P277A in Mcobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 26862 11808285 BCGMEX_0021c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169497.1 25894 R 717522 CDS YP_005169498.1 378769765 11808286 complement(27004..27423) 1 NC_016804.1 putative transcriptional regulatory protein whiB-like protein 27423 whiB5 11808286 whiB5 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein whiB-like protein YP_005169498.1 27004 R 717522 CDS YP_005169499.1 378769766 11808287 27576..28346 1 NC_016804.1 transcriptional regulator 28346 11808287 BCGMEX_0023 Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005169499.1 27576 D 717522 CDS YP_005169500.1 378769767 11808288 28343..29176 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, and other mycobacteria, Rv0024 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base deletion (C-*) splits Rv0024 into 2 parts; putative secreted protein P60-related protein 29176 11808288 BCGMEX_0024 Mycobacterium bovis BCG str. Mexico putative secreted protein P60-related protein YP_005169500.1 28343 D 717522 CDS YP_005169501.1 378769768 11808290 29225..29587 1 NC_016804.1 Differs from Rv0025 by 1aa, L73P in Mcobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 29587 11808290 BCGMEX_0026 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169501.1 29225 D 717522 CDS YP_005169502.1 378769769 11808291 29702..31135 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 4 bp insertion (*-ATCG) leads to a longer protein with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (477 aa versus 448 aa). Differs from Rv0026 by 1aa, P93Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 31135 11808291 BCGMEX_0027 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169502.1 29702 D 717522 CDS YP_005169503.1 378769770 11808292 31173..31490 1 NC_016804.1 hypothetical protein 31490 11808292 BCGMEX_0028 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169503.1 31173 D 717522 CDS YP_005169504.1 378769771 11808293 31498..31803 1 NC_016804.1 hypothetical protein 31803 11808293 BCGMEX_0029 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169504.1 31498 D 717522 CDS YP_005169505.1 378769772 11808294 32041..33138 1 NC_016804.1 Differs from Rv0029 by 1aa, N190H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 33138 11808294 BCGMEX_0030 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169505.1 32041 D 717522 CDS YP_005169506.1 378769773 11808295 33208..33537 1 NC_016804.1 hypothetical protein 33537 11808295 BCGMEX_0031 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169506.1 33208 D 717522 CDS YP_005169507.1 378769774 11808296 33566..33778 1 NC_016804.1 putative remnant of a transposase 33778 11808296 BCGMEX_0032 Mycobacterium bovis BCG str. Mexico putative remnant of a transposase YP_005169507.1 33566 D 717522 CDS YP_005169508.1 378769775 11808297 34279..36594 1 NC_016804.1 8-amino-3-oxonanoate synthase 36594 bioF2 11808297 bioF2 Mycobacterium bovis BCG str. Mexico 8-amino-3-oxonanoate synthase YP_005169508.1 34279 D 717522 CDS YP_005169509.1 378769776 11808298 36591..36854 1 NC_016804.1 acyl carrier protein 36854 acpA 11808298 acpA Mycobacterium bovis BCG str. Mexico acyl carrier protein YP_005169509.1 36591 D 717522 CDS YP_005169510.1 378769777 11808299 36851..37246 1 NC_016804.1 hypothetical protein 37246 11808299 BCGMEX_0035 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169510.1 36851 D 717522 CDS YP_005169511.1 378769778 11808300 37243..38931 1 NC_016804.1 putative fatty-acid-CoA ligase 38931 fadD34 11808300 fadD34 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005169511.1 37243 D 717522 CDS YP_005169512.1 378769779 11808301 complement(39132..39812) 1 NC_016804.1 Differs from Mb0037c and Rv0036c by 1aa in BCG Pasteur, BCG Tokyo and BCG Mexico, L186P in BCG Pasteur, and at C-terminal end due to frameshift resulting from 1 bp deletion at position Equivalent to Mycobacterium tuberculosis H37Rv, after codon 202 in BCG Pasteur, Tokyo and Mexico; hypothetical protein 39812 11808301 BCGMEX_0037c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169512.1 39132 R 717522 CDS YP_005169513.1 378769780 11808302 complement(39860..41185) 1 NC_016804.1 putative integral membrane protein 41185 11808302 BCGMEX_0038c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005169513.1 39860 R 717522 CDS YP_005169514.1 378769781 11808303 41287..41895 1 NC_016804.1 hypothetical protein 41895 11808303 BCGMEX_0039 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169514.1 41287 D 717522 CDS YP_005169515.1 378769782 11808304 complement(41987..42334) 1 NC_016804.1 Differs from Rv0039c by 1aa, F24C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 42334 11808304 BCGMEX_0040c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169515.1 41987 R 717522 CDS YP_005169516.1 378769783 11808305 complement(42416..43348) 1 NC_016804.1 proline-rich 28 kDa antigen 43348 mtc28 11808305 mtc28 Mycobacterium bovis BCG str. Mexico proline-rich 28 kDa antigen YP_005169516.1 42416 R 717522 CDS YP_005169517.1 378769784 11808306 43545..46454 1 NC_016804.1 leucyl-tRNA synthetase 46454 leuS 11808306 leuS Mycobacterium bovis BCG str. Mexico leucyl-tRNA synthetase YP_005169517.1 43545 D 717522 CDS YP_005169518.1 378769785 11808307 complement(46564..47190) 1 NC_016804.1 putative transcriptional regulatory protein, MarR family 47190 11808307 BCGMEX_0043c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, MarR family YP_005169518.1 46564 R 717522 CDS YP_005169519.1 378769786 11808308 complement(47349..48083) 1 NC_016804.1 putative transcriptional regulatory protein, GntR family 48083 11808308 BCGMEX_0044c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, GntR family YP_005169519.1 47349 R 717522 CDS YP_005169520.1 378769787 11808309 complement(48216..49010) 1 NC_016804.1 putative oxidoreductase 49010 11808309 BCGMEX_0045c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169520.1 48216 R 717522 CDS YP_005169521.1 378769788 11808310 complement(49026..49922) 1 NC_016804.1 putative hydrolase 49922 11808310 BCGMEX_0046c Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005169521.1 49026 R 717522 CDS YP_005169522.1 378769789 11808311 complement(50004..51107) 1 NC_016804.1 Differs from Mb0047c by 1aa, T120I, and from Rv0046c by 2aa, T120I, G190R in BCG Pasteur, BCG Tokio and BCG Mexico; inositol-1-phosphate synthase 51107 11808311 BCGMEX_0047c Mycobacterium bovis BCG str. Mexico inositol-1-phosphate synthase YP_005169522.1 50004 R 717522 CDS YP_005169523.1 378769790 11808312 complement(51168..51710) 1 NC_016804.1 hypothetical protein 51710 11808312 BCGMEX_0048c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169523.1 51168 R 717522 CDS YP_005169524.1 378769791 11808313 complement(51811..52680) 1 NC_016804.1 Differs from Rv0048c by 1aa, A250V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 52680 11808313 BCGMEX_0049c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169524.1 51811 R 717522 CDS YP_005169525.1 378769792 11808314 52814..53227 1 NC_016804.1 hypothetical protein 53227 11808314 BCGMEX_0050 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169525.1 52814 D 717522 CDS YP_005169526.1 378769793 11808315 53646..55691 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, insertion of 3 codons after position 632 leads to a slightly longer product compared to its homologs in Mycobacterium tuberculosis strain H37Rv (681 aa versus 678 aa) and Mycobacterium bovis AF2122/97 (681 aa versus 680 aa). In addition, differs from Rv0050 by 1aa, L6P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative bifunctional penicillin-binding protein 1A/1B 55691 ponA1 11808315 ponA1 Mycobacterium bovis BCG str. Mexico putative bifunctional penicillin-binding protein 1A/1B YP_005169526.1 53646 D 717522 CDS YP_005169527.1 378769794 11808316 55688..57370 1 NC_016804.1 transmembrane protein 57370 11808316 BCGMEX_0052 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169527.1 55688 D 717522 CDS YP_005169528.1 378769795 11808317 57402..57965 1 NC_016804.1 hypothetical protein 57965 11808317 BCGMEX_0053 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169528.1 57402 D 717522 CDS YP_005169529.1 378769796 11808318 58184..58474 1 NC_016804.1 30S ribosomal protein S6 58474 rpsF 11808318 rpsF Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S6 YP_005169529.1 58184 D 717522 CDS YP_005169530.1 378769797 11808319 58578..59072 1 NC_016804.1 ssDNA-binding protein 59072 ssb 11808319 ssb Mycobacterium bovis BCG str. Mexico ssDNA-binding protein YP_005169530.1 58578 D 717522 CDS YP_005169531.1 378769798 11808320 59114..59368 1 NC_016804.1 30S ribosomal protein S18 59368 rpsR1 11808320 rpsR1 Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S18 YP_005169531.1 59114 D 717522 CDS YP_005169532.1 378769799 11808321 59401..59859 1 NC_016804.1 50S ribosomal protein L9 59859 rplI 11808321 rplI Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L9 YP_005169532.1 59401 D 717522 CDS YP_005169533.1 378769800 11808322 59888..60409 1 NC_016804.1 hypothetical protein 60409 11808322 BCGMEX_0058 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169533.1 59888 D 717522 CDS YP_005169534.1 378769801 11808323 60388..63012 1 NC_016804.1 Differs from Rv0058 by 1aa, G552R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Replicative DNA helicase 63012 dnaB 11808323 dnaB Mycobacterium bovis BCG str. Mexico Replicative DNA helicase YP_005169534.1 60388 D 717522 CDS YP_005169535.1 378769802 11808324 63192..63884 1 NC_016804.1 hypothetical protein 63884 11808324 BCGMEX_0060 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169535.1 63192 D 717522 CDS YP_005169536.1 378769803 11808325 63901..64959 1 NC_016804.1 hypothetical protein 64959 11808325 BCGMEX_0061 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169536.1 63901 D 717522 CDS YP_005169537.1 378769804 11808326 64983..65408 1 NC_016804.1 hypothetical protein 65408 11808326 BCGMEX_0062 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169537.1 64983 D 717522 CDS YP_005169538.1 378769805 11808327 65544..66686 1 NC_016804.1 Differs from Mb0063 by 1aa, A72D, and from Rv0062 by 2aa, A72D, V106I in BCG Pasteur, BCG Tokyo and BCG Mexico; putative cellulase 66686 celA1 11808327 celA1 Mycobacterium bovis BCG str. Mexico putative cellulase YP_005169538.1 65544 D 717522 CDS YP_005169539.1 378769806 11808328 66915..68354 1 NC_016804.1 putative oxidoreductase 68354 11808328 BCGMEX_0064 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169539.1 66915 D 717522 CDS YP_005169540.1 378769807 11808329 68612..71551 1 NC_016804.1 Differs from Mb0065 by 1aa, T435I, and from Rv0064 by 4aa, T435I, D457G, F550V, P906R in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 71551 11808329 BCGMEX_0065 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169540.1 68612 D 717522 CDS YP_005169541.1 378769808 11808330 71618..71857 1 NC_016804.1 Differs from Rv0064A by 1aa, V48A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 71857 11808330 BCGMEX_0066 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169541.1 71618 D 717522 CDS YP_005169542.1 378769809 11808331 71850..72251 1 NC_016804.1 hypothetical protein 72251 11808331 BCGMEX_0067 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169542.1 71850 D 717522 CDS YP_005169543.1 378769810 11808332 complement(72303..74540) 1 NC_016804.1 Differs from Rv0066c by 1aa, N117K in in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur,BCG Tokyo and BCG Mexico; isocitrate dehydrogenase 74540 icd2 11808332 icd2 Mycobacterium bovis BCG str. Mexico isocitrate dehydrogenase YP_005169543.1 72303 R 717522 CDS YP_005169544.1 378769811 11808333 complement(74658..75227) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 75227 11808333 BCGMEX_0069c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005169544.1 74658 R 717522 CDS YP_005169545.1 378769812 11808334 75330..76241 1 NC_016804.1 Differs from Rv0068 by 1aa, L214V in Mycobacterium bovis, Mycobacterium tuberculosis CDC1551, BCG Pasteur,BCG Tokyo and BCG Mexico; short-chain dehydrogenase 76241 11808334 BCGMEX_0070 Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005169545.1 75330 D 717522 CDS YP_005169546.1 378769813 11808335 complement(76266..77651) 1 NC_016804.1 putative L-serine dehydratase 77651 sdaA 11808335 sdaA Mycobacterium bovis BCG str. Mexico putative L-serine dehydratase YP_005169546.1 76266 R 717522 CDS YP_005169547.1 378769814 11808336 complement(77648..78925) 1 NC_016804.1 Differs from Rv0070c by 1aa, G265E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative serine hydroxymethyltransferase 78925 glyA2 11808336 glyA2 Mycobacterium bovis BCG str. Mexico putative serine hydroxymethyltransferase YP_005169547.1 77648 R 717522 CDS YP_005169548.1 378769815 11808337 79515..80267 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 45 bp insertion (5 copies of VDP repeat) leads to longer products compared to its homologs in Mycobacterium tuberculosis strain H37Rv (250 aa versus 235 aa) and Mycobacterium bovis (250 aa versus 238 aa); Maturase-related protein 80267 11808337 BCGMEX_0073 Mycobacterium bovis BCG str. Mexico Maturase-related protein YP_005169548.1 79515 D 717522 CDS YP_005169549.1 378769816 11808338 80698..81747 1 NC_016804.1 putative glutamine-transport transmembrane protein ABC transporter 81747 11808338 BCGMEX_0074 Mycobacterium bovis BCG str. Mexico putative glutamine-transport transmembrane protein ABC transporter YP_005169549.1 80698 D 717522 CDS YP_005169550.1 378769817 11808339 81750..82742 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0073 exists as a single gene as in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico. In Mycobacterium bovis, a frameshift due to a single base deletion (A-*) splits Rv0073 into 2 parts, Mb0074 and Mb0075; putative glutamine-transport ATP-binding protein ABC transporter 82742 11808339 BCGMEX_0075 Mycobacterium bovis BCG str. Mexico putative glutamine-transport ATP-binding protein ABC transporter YP_005169550.1 81750 D 717522 CDS YP_005169551.1 378769818 11808340 82822..84057 1 NC_016804.1 hypothetical protein 84057 11808340 BCGMEX_0076 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169551.1 82822 D 717522 CDS YP_005169552.1 378769819 11808341 84070..85242 1 NC_016804.1 Differs from Rv0075 and Mb0077 by 1aa, G326D in BCG Pasteur, BCG Tokyo and BCG Mexico; aminotransferase 85242 11808341 BCGMEX_0077 Mycobacterium bovis BCG str. Mexico aminotransferase YP_005169552.1 84070 D 717522 CDS YP_005169553.1 378769820 11808342 complement(85257..85646) 1 NC_016804.1 hypothetical protein 85646 11808342 BCGMEX_0078c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169553.1 85257 R 717522 CDS YP_005169554.1 378769821 11808343 complement(85710..86540) 1 NC_016804.1 putative oxidoreductase 86540 11808343 BCGMEX_0079c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169554.1 85710 R 717522 CDS YP_005169555.1 378769822 11808344 86602..87207 1 NC_016804.1 Differs from Rv0078 by 1aa, V113I in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 87207 11808344 BCGMEX_0080 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005169555.1 86602 D 717522 CDS YP_005169556.1 378769823 11808345 complement(87282..87875) 1 NC_016804.1 hypothetical protein 87875 11808345 BCGMEX_0081c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169556.1 87282 R 717522 CDS YP_005169557.1 378769824 11808346 complement(87872..88084) 1 NC_016804.1 hypothetical protein 88084 11808346 BCGMEX_0082c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169557.1 87872 R 717522 CDS YP_005169558.1 378769825 11808347 88278..89099 1 NC_016804.1 hypothetical protein 89099 11808347 BCGMEX_0083 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169558.1 88278 D 717522 CDS YP_005169559.1 378769826 11808348 89096..89554 1 NC_016804.1 Differs from Mb0083 by 1aa, C35R, and from Rv0080 by 2aa, C35R, V60G in BCG Pasteur and BCG Mexico. Differs from Rv0080 by 1aa, V60G in BCG Tokyo; hypothetical protein 89554 11808348 BCGMEX_0084 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169559.1 89096 D 717522 CDS YP_005169560.1 378769827 11808349 89649..89993 1 NC_016804.1 putative transcriptional regulatory protein, ArsR family 89993 11808349 BCGMEX_0085 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, ArsR family YP_005169560.1 89649 D 717522 CDS YP_005169561.1 378769828 11808350 89998..90477 1 NC_016804.1 Differs from Rv0082 by 1aa, R74Q in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 90477 11808350 BCGMEX_0086 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169561.1 89998 D 717522 CDS YP_005169562.1 378769829 11808351 90474..92402 1 NC_016804.1 In Mycobacterium bovis, a single base transversion (a-t) leads to a slightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (642 aa versus 640 aa).Differs from Mb0086 by 1aa, A177V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 92402 11808351 BCGMEX_0087 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169562.1 90474 D 717522 CDS YP_005169563.1 378769830 11808352 92402..93352 1 NC_016804.1 putative formate hydrogenlyase 93352 hycD 11808352 hycD Mycobacterium bovis BCG str. Mexico putative formate hydrogenlyase YP_005169563.1 92402 D 717522 CDS YP_005169564.1 378769831 11808353 93363..94025 1 NC_016804.1 putative hydrogenase 94025 hycP 11808353 hycP Mycobacterium bovis BCG str. Mexico putative hydrogenase YP_005169564.1 93363 D 717522 CDS YP_005169565.1 378769832 11808354 94025..95491 1 NC_016804.1 Differs from Rv0086 by 1aa, T118M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative hydrogenase 95491 hycQ 11808354 hycQ Mycobacterium bovis BCG str. Mexico putative hydrogenase YP_005169565.1 94025 D 717522 CDS YP_005169566.1 378769833 11808355 95488..96966 1 NC_016804.1 Differs from Rv0087 by 1aa, I230V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur,BCG Tokyo and BCG Mexico; putative formate hydrogenlyase 96966 hycE 11808355 hycE Mycobacterium bovis BCG str. Mexico putative formate hydrogenlyase YP_005169566.1 95488 D 717522 CDS YP_005169567.1 378769834 11808356 97001..97675 1 NC_016804.1 hypothetical protein 97675 11808356 BCGMEX_0092 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169567.1 97001 D 717522 CDS YP_005169568.1 378769835 11808357 97832..98425 1 NC_016804.1 putative methyltransferasa/methylase 98425 11808357 BCGMEX_0093 Mycobacterium bovis BCG str. Mexico putative methyltransferasa/methylase YP_005169568.1 97832 D 717522 CDS YP_005169569.1 378769836 11808358 98554..99324 1 NC_016804.1 hypothetical protein 99324 11808358 BCGMEX_0094 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169569.1 98554 D 717522 CDS YP_005169570.1 378769837 11808359 99758..100525 1 NC_016804.1 MTA/SAH nucleosidase 100525 mtn 11808359 mtn Mycobacterium bovis BCG str. Mexico MTA/SAH nucleosidase YP_005169570.1 99758 D 717522 CDS YP_005169571.1 378769838 11808360 100657..102942 1 NC_016804.1 Differs from Rv0092 by 1aa, A3T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; cation-transporting P-type ATPase A 102942 ctpA 11808360 ctpA Mycobacterium bovis BCG str. Mexico cation-transporting P-type ATPase A YP_005169571.1 100657 D 717522 CDS YP_005169572.1 378769839 11808361 complement(102889..103737) 1 NC_016804.1 Differs from Rv0093c by 1aa, R22C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 103737 11808361 BCGMEX_0097c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169572.1 102889 R 717522 CDS YP_005169573.1 378769840 11808362 complement(103784..104737) 1 NC_016804.1 Differs from Rv0094c by 3aa, D256E, W296R, K315E in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 104737 11808362 BCGMEX_0098c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169573.1 103784 R 717522 CDS YP_005169574.1 378769841 11808363 complement(104508..105290) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0095c and Rv1588 exist as separate genes in their respective positions. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 73 bp substitution leads to a single combined gene. Differs from Rv0095c by 5aa, E57D, T70S, V85A, V91G, A92Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 105290 11808363 BCGMEX_0099c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169574.1 104508 R 717522 CDS YP_005169575.1 378769842 11808364 105399..106790 1 NC_016804.1 Differs from Rv0096 by 1aa, W182R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 106790 PPE1 11808364 PPE1 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169575.1 105399 D 717522 CDS YP_005169576.1 378769843 11808365 106809..107678 1 NC_016804.1 putative oxidoreductase 107678 11808365 BCGMEX_0101 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169576.1 106809 D 717522 CDS YP_005169577.1 378769844 11808366 107675..108226 1 NC_016804.1 hypothetical protein 108226 11808366 BCGMEX_0102 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169577.1 107675 D 717522 CDS YP_005169578.1 378769845 11808367 108231..109853 1 NC_016804.1 putative fatty-acid-CoA ligase 109853 fadD10 11808367 fadD10 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005169578.1 108231 D 717522 CDS YP_005169579.1 378769846 11808368 109858..110094 1 NC_016804.1 hypothetical protein 110094 11808368 BCGMEX_0104 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169579.1 109858 D 717522 CDS YP_005169580.1 378769847 11808369 110076..117614 1 NC_016804.1 putative peptide synthetase 117614 nrp 11808369 nrp Mycobacterium bovis BCG str. Mexico putative peptide synthetase YP_005169580.1 110076 D 717522 CDS YP_005169581.1 378769848 11808370 117789..119774 1 NC_016804.1 putative integral membrane protein 119774 11808370 BCGMEX_0106 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005169581.1 117789 D 717522 CDS YP_005169582.1 378769849 11808371 complement(119990..122248) 1 NC_016804.1 Differs from Rv0103c by 1aa, S22L in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; cation-transporting P-type ATPase B 122248 ctpB 11808371 ctpB Mycobacterium bovis BCG str. Mexico cation-transporting P-type ATPase B YP_005169582.1 119990 R 717522 CDS YP_005169583.1 378769850 11808372 122392..123906 1 NC_016804.1 hypothetical protein 123906 11808372 BCGMEX_0108 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169583.1 122392 D 717522 CDS YP_005169584.1 378769851 11808373 complement(124055..124339) 1 NC_016804.1 50S ribosomal protein L28 124339 rpmB1 11808373 rpmB1 Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L28 YP_005169584.1 124055 R 717522 CDS YP_005169585.1 378769852 11808374 124449..125645 1 NC_016804.1 hypothetical protein 125645 11808374 BCGMEX_0110 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169585.1 124449 D 717522 CDS YP_005169586.1 378769853 11808375 complement(125740..130617) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base insertion (*-T) leads to a product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv differs from Rv0107c by 3aa, V136A, P1247S, S1327A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative cation-transporter ATPase I 130617 ctpI 11808375 ctpI Mycobacterium bovis BCG str. Mexico putative cation-transporter ATPase I YP_005169586.1 125740 R 717522 CDS YP_005169587.1 378769854 11808376 complement(130971..131180) 1 NC_016804.1 hypothetical protein 131180 11808376 BCGMEX_0112c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169587.1 130971 R 717522 CDS YP_005169588.1 378769855 11808377 131459..132949 1 NC_016804.1 Differs from Rv0109 by 1aa, G346R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 132949 PE_PGRS1 11808377 PE_PGRS1 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005169588.1 131459 D 717522 CDS YP_005169589.1 378769856 11808378 133097..133846 1 NC_016804.1 hypothetical protein 133846 11808378 BCGMEX_0114 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169589.1 133097 D 717522 CDS YP_005169590.1 378769857 11808379 134027..136084 1 NC_016804.1 putative transmembrane acyltransferase 136084 11808379 BCGMEX_0115 Mycobacterium bovis BCG str. Mexico putative transmembrane acyltransferase YP_005169590.1 134027 D 717522 CDS YP_005169591.1 378769858 11808380 136366..137322 1 NC_016804.1 putative gdp-mannose 4,6-dehydratase 137322 gca 11808380 gca Mycobacterium bovis BCG str. Mexico putative gdp-mannose 4,6-dehydratase YP_005169591.1 136366 D 717522 CDS YP_005169592.1 378769859 11808381 137396..137986 1 NC_016804.1 phosphoheptose isomerase 137986 gmhA 11808381 gmhA Mycobacterium bovis BCG str. Mexico phosphoheptose isomerase YP_005169592.1 137396 D 717522 CDS YP_005169593.1 378769860 11808382 138018..138590 1 NC_016804.1 Differs from Rv0114 by 1aa, R121G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative dehydratase 138590 11808382 BCGMEX_0118 Mycobacterium bovis BCG str. Mexico putative dehydratase YP_005169593.1 138018 D 717522 CDS YP_005169594.1 378769861 11808383 138590..139657 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base insertion (*-c) leads to shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv. In addition, in Mycobacterium bovis, a single base insertion leads to a different NH2 part; putative sugar kinase 139657 11808383 BCGMEX_0119 Mycobacterium bovis BCG str. Mexico putative sugar kinase YP_005169594.1 138590 D 717522 CDS YP_005169595.1 378769862 11808384 complement(140345..141100) 1 NC_016804.1 membrane protein 141100 11808384 BCGMEX_0120c Mycobacterium bovis BCG str. Mexico membrane protein YP_005169595.1 140345 R 717522 CDS YP_005169596.1 378769863 11808385 141278..142222 1 NC_016804.1 Oxidative stress response regulatory protein 142222 oxyS 11808385 oxyS Mycobacterium bovis BCG str. Mexico Oxidative stress response regulatory protein YP_005169596.1 141278 D 717522 CDS YP_005169597.1 378769864 11808386 complement(142206..143954) 1 NC_016804.1 Differs from Rv0118c by 1aa, G224S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxalyl-CoA decarboxylase 143954 oxcA 11808386 oxcA Mycobacterium bovis BCG str. Mexico putative oxalyl-CoA decarboxylase YP_005169597.1 142206 R 717522 CDS YP_005169598.1 378769865 11808387 144127..145704 1 NC_016804.1 acyl-CoA synthetase 145704 fadD7 11808387 fadD7 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005169598.1 144127 D 717522 CDS YP_005169599.1 378769866 11808388 complement(145705..147849) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium tuberculosis strain H37Rv, fusA2 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 2bp to 1bp substitution (GC-T), splits fusA2 into 2 parts, fusA2a and fusA2b. Differs from Rv0120c by 2aa, W106R, S562N; Elongation factor G-related protein 147849 fusA2b 11808388 fusA2b Mycobacterium bovis BCG str. Mexico Elongation factor G-related protein YP_005169599.1 145705 R 717522 CDS YP_005169600.1 378769867 11808389 complement(147985..148419) 1 NC_016804.1 hypothetical protein 148419 11808389 BCGMEX_0125c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169600.1 147985 R 717522 CDS YP_005169601.1 378769868 11808390 148568..148936 1 NC_016804.1 hypothetical protein 148936 11808390 BCGMEX_0126 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169601.1 148568 D 717522 CDS YP_005169602.1 378769869 11808391 148933..149301 1 NC_016804.1 hypothetical protein 149301 11808391 BCGMEX_0127 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169602.1 148933 D 717522 CDS YP_005169603.1 378769870 11808392 149610..151226 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 180 bp insertion leads to a longer product in the 3' direction compared to its homolog in Mycobacterium tuberculosis strain H37Rv (538 aa versus 487 aa); PE-PGRS family protein 151226 PE_PGRS2 11808392 PE_PGRS2 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005169603.1 149610 D 717522 CDS YP_005169604.1 378769871 11808393 151378..152445 1 NC_016804.1 putative serine protease 152445 pepA 11808393 pepA Mycobacterium bovis BCG str. Mexico putative serine protease YP_005169604.1 151378 D 717522 CDS YP_005169605.1 378769872 11808394 152554..154359 1 NC_016804.1 Trehalose synthase 154359 treS 11808394 treS Mycobacterium bovis BCG str. Mexico Trehalose synthase YP_005169605.1 152554 D 717522 CDS YP_005169606.1 378769873 11808395 154462..155829 1 NC_016804.1 Differs from Rv0127 by 1aa, P18S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 155829 11808395 BCGMEX_0131 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169606.1 154462 D 717522 CDS YP_005169607.1 378769874 11808396 155897..156676 1 NC_016804.1 transmembrane protein 156676 11808396 BCGMEX_0132 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169607.1 155897 D 717522 CDS YP_005169608.1 378769875 11808397 complement(156808..157830) 1 NC_016804.1 antigen 85-C 157830 fbpC 11808397 fbpC Mycobacterium bovis BCG str. Mexico antigen 85-C YP_005169608.1 156808 R 717522 CDS YP_005169609.1 378769876 11808398 158077..158532 1 NC_016804.1 hypothetical protein 158532 11808398 BCGMEX_0134 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169609.1 158077 D 717522 CDS YP_005169610.1 378769877 11808399 complement(158545..159888) 1 NC_016804.1 putative acyl-CoA dehydrogenase 159888 fadE1 11808399 fadE1 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005169610.1 158545 R 717522 CDS YP_005169611.1 378769878 11808400 complement(159930..161012) 1 NC_016804.1 Differs from Mb0137c by 1aa, E147K in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; F420-dependent glucose-6-phosphate dehydrogenase 161012 fgd2 11808400 fgd2 Mycobacterium bovis BCG str. Mexico F420-dependent glucose-6-phosphate dehydrogenase YP_005169611.1 159930 R 717522 CDS YP_005169612.1 378769879 11808401 161099..161581 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, and Mycobacterium bovis AF2122/97, codon 161 is TAC and in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, TAA; putative acetyltransferase 161581 11808401 BCGMEX_0137 Mycobacterium bovis BCG str. Mexico putative acetyltransferase YP_005169612.1 161099 D 717522 CDS YP_005169613.1 378769880 11808405 complement(162874..163479) 1 NC_016804.1 TetR family transcriptional regulator 163479 11808405 BCGMEX_0141c Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005169613.1 162874 R 717522 CDS YP_005169614.1 378769881 11808406 163596..164921 1 NC_016804.1 putative cytochrome P450 138 164921 cyp138 11808406 cyp138 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 138 YP_005169614.1 163596 D 717522 CDS YP_005169615.1 378769882 11808407 complement(164942..165490) 1 NC_016804.1 peptide methionine sulfoxide reductase msrA 165490 msrA 11808407 msrA Mycobacterium bovis BCG str. Mexico peptide methionine sulfoxide reductase msrA YP_005169615.1 164942 R 717522 CDS YP_005169616.1 378769883 11808408 165553..166056 1 NC_016804.1 Differs from Mb0143 by 1aa, D96G in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 166056 11808408 BCGMEX_0144 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169616.1 165553 D 717522 CDS YP_005169617.1 378769884 11808409 166057..167079 1 NC_016804.1 Differs from Mb0144 by 1aa, R227H in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; dihydroflavonol-4-reductase 167079 11808409 BCGMEX_0145 Mycobacterium bovis BCG str. Mexico dihydroflavonol-4-reductase YP_005169617.1 166057 D 717522 CDS YP_005169618.1 378769885 11808410 167140..167520 1 NC_016804.1 hypothetical protein 167520 11808410 BCGMEX_0146 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169618.1 167140 D 717522 CDS YP_005169619.1 378769886 11808411 complement(167501..167911) 1 NC_016804.1 hypothetical protein 167911 11808411 BCGMEX_0147c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169619.1 167501 R 717522 CDS YP_005169620.1 378769887 11808412 167941..168867 1 NC_016804.1 hypothetical protein 168867 11808412 BCGMEX_0148 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169620.1 167941 D 717522 CDS YP_005169621.1 378769888 11808413 complement(168934..170412) 1 NC_016804.1 Differs from Rv0143c by 1aa, L34F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 170412 11808413 BCGMEX_0149c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169621.1 168934 R 717522 CDS YP_005169622.1 378769889 11808414 170514..171356 1 NC_016804.1 TetR family transcriptional regulator 171356 11808414 BCGMEX_0150 Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005169622.1 170514 D 717522 CDS YP_005169623.1 378769890 11808415 171445..172398 1 NC_016804.1 hypothetical protein 172398 11808415 BCGMEX_0151 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169623.1 171445 D 717522 CDS YP_005169624.1 378769891 11808416 172441..173373 1 NC_016804.1 hypothetical protein 173373 11808416 BCGMEX_0152 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169624.1 172441 D 717522 CDS YP_005169625.1 378769892 11808417 173468..174988 1 NC_016804.1 aldehyde dehydrogenase 174988 11808417 BCGMEX_0153 Mycobacterium bovis BCG str. Mexico aldehyde dehydrogenase YP_005169625.1 173468 D 717522 CDS YP_005169626.1 378769893 11808418 175063..175923 1 NC_016804.1 putative short-chain type dehydrogenase/reductase 175923 11808418 BCGMEX_0154 Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005169626.1 175063 D 717522 CDS YP_005169627.1 378769894 11808419 175930..176898 1 NC_016804.1 putative quinone oxidoreductase 176898 11808419 BCGMEX_0155 Mycobacterium bovis BCG str. Mexico putative quinone oxidoreductase YP_005169627.1 175930 D 717522 CDS YP_005169628.1 378769895 11808420 complement(176895..177182) 1 NC_016804.1 hypothetical protein 177182 11808420 BCGMEX_0156c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169628.1 176895 R 717522 CDS YP_005169629.1 378769896 11808421 complement(177773..179539) 1 NC_016804.1 Differs from Rv0151c by 1aa, R26G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 179539 PE1 11808421 PE1 Mycobacterium bovis BCG str. Mexico PE family protein YP_005169629.1 177773 R 717522 CDS YP_005169630.1 378769897 11808422 complement(179549..181126) 1 NC_016804.1 PE family protein 181126 PE2 11808422 PE2 Mycobacterium bovis BCG str. Mexico PE family protein YP_005169630.1 179549 R 717522 CDS YP_005169631.1 378769898 11808423 complement(181385..182215) 1 NC_016804.1 Differs from Rv0153c by 1aa, G105D in BCG Pasteur, BCG Tokyo and BCG Mexico; phosphotyrosine protein phosphatase 182215 ptbB 11808423 ptbB Mycobacterium bovis BCG str. Mexico phosphotyrosine protein phosphatase YP_005169631.1 181385 R 717522 CDS YP_005169632.1 378769899 11808424 complement(182217..183428) 1 NC_016804.1 putative acyl-CoA dehydrogenase 183428 fadE2 11808424 fadE2 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005169632.1 182217 R 717522 CDS YP_005169633.1 378769900 11808425 183852..184952 1 NC_016804.1 putative NAD(P) transhydrogenase subunit alpha 184952 pntAa 11808425 pntAa Mycobacterium bovis BCG str. Mexico putative NAD(P) transhydrogenase subunit alpha YP_005169633.1 183852 D 717522 CDS YP_005169634.1 378769901 11808426 184953..185285 1 NC_016804.1 Differs from Rv0156 by 1aa, C2Y in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative NAD(P) transhydrogenase subunit alpha 185285 pntAb 11808426 pntAb Mycobacterium bovis BCG str. Mexico putative NAD(P) transhydrogenase subunit alpha YP_005169634.1 184953 D 717522 CDS YP_005169635.1 378769902 11808427 185282..186709 1 NC_016804.1 putative NAD(P) transhydrogenase subunit beta 186709 pntB 11808427 pntB Mycobacterium bovis BCG str. Mexico putative NAD(P) transhydrogenase subunit beta YP_005169635.1 185282 D 717522 CDS YP_005169636.1 378769903 11808428 187015..187659 1 NC_016804.1 TetR family transcriptional regulator 187659 11808428 BCGMEX_0164 Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005169636.1 187015 D 717522 CDS YP_005169637.1 378769904 11808429 complement(187663..189069) 1 NC_016804.1 Differs from Rv0159c by 1aa, T255P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 189069 PE3 11808429 PE3 Mycobacterium bovis BCG str. Mexico PE family protein YP_005169637.1 187663 R 717522 CDS YP_005169638.1 378769905 11808430 complement(189161..190669) 1 NC_016804.1 Differs from Rv0160c by 2aa, T116A, T211A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 190669 PE4 11808430 PE4 Mycobacterium bovis BCG str. Mexico PE family protein YP_005169638.1 189161 R 717522 CDS YP_005169639.1 378769906 11808431 190837..192186 1 NC_016804.1 putative oxidoreductase 192186 11808431 BCGMEX_0167 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169639.1 190837 D 717522 CDS YP_005169640.1 378769907 11808432 complement(192214..193365) 1 NC_016804.1 Differs from Rv0162c and Mb0167c by 1aa, R41H in BCG Pasteur, BCG Tokyo and BCG Mexico; putative zinc-type alcohol dehydrogenase e subunit 193365 adhE1 11808432 adhE1 Mycobacterium bovis BCG str. Mexico putative zinc-type alcohol dehydrogenase e subunit YP_005169640.1 192214 R 717522 CDS YP_005169641.1 378769908 11808433 193347..193802 1 NC_016804.1 hypothetical protein 193802 11808433 BCGMEX_0169 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169641.1 193347 D 717522 CDS YP_005169642.1 378769909 11808434 193856..194341 1 NC_016804.1 hypothetical protein 194341 11808434 BCGMEX_0170 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169642.1 193856 D 717522 CDS YP_005169643.1 378769910 11808435 complement(194355..195170) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0165c exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a 2bp insertion (*-CC) leads to a product with a different COOH terminus; GntR family transcriptional regulator 195170 11808435 BCGMEX_0171c Mycobacterium bovis BCG str. Mexico GntR family transcriptional regulator YP_005169643.1 194355 R 717522 CDS YP_005169644.1 378769911 11808436 195225..196889 1 NC_016804.1 Differs from Rv0166 by 2aa, A123V, A192S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA synthetase 196889 fadD5 11808436 fadD5 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005169644.1 195225 D 717522 CDS YP_005169645.1 378769912 11808437 197175..197891 1 NC_016804.1 In Mycobacterium bovis BCG Mexico a single base transition (G-A) leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (238 aa versus 265 aa); putative integral membrane protein 197891 yrbE1A 11808437 yrbE1A Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005169645.1 197175 D 717522 CDS YP_005169646.1 378769913 11808438 197893..198762 1 NC_016804.1 putative integral membrane protein 198762 yrbE1B 11808438 yrbE1B Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005169646.1 197893 D 717522 CDS YP_005169647.1 378769914 11808439 198767..200131 1 NC_016804.1 Differs from Rv0169 by 2aa, A313S, S359P. Differs from Rv0169 by 2aa, A313S, S359P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 200131 mce1A 11808439 mce1A Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005169647.1 198767 D 717522 CDS YP_005169648.1 378769915 11808440 200128..201168 1 NC_016804.1 Differs from Rv0170 by 1aa, T179I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 201168 mce1B 11808440 mce1B Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005169648.1 200128 D 717522 CDS YP_005169649.1 378769916 11808441 201165..202712 1 NC_016804.1 Differs from Rv0171 by 1aa, D212E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 202712 mce1C 11808441 mce1C Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005169649.1 201165 D 717522 CDS YP_005169650.1 378769917 11808442 202709..204301 1 NC_016804.1 MCE-family protein 204301 mce1D 11808442 mce1D Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005169650.1 202709 D 717522 CDS YP_005169651.1 378769918 11808443 204298..205470 1 NC_016804.1 putative MCE-family lipoprotein LPRL 205470 lprK 11808443 lprK Mycobacterium bovis BCG str. Mexico putative MCE-family lipoprotein LPRL YP_005169651.1 204298 D 717522 CDS YP_005169652.1 378769919 11808444 205464..207011 1 NC_016804.1 Differs from Rv0174 by 1aa, P370L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 207011 mce1F 11808444 mce1F Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005169652.1 205464 D 717522 CDS YP_005169653.1 378769920 11808445 207047..207688 1 NC_016804.1 MCE associated membrane 207688 11808445 BCGMEX_0181 Mycobacterium bovis BCG str. Mexico MCE associated membrane YP_005169653.1 207047 D 717522 CDS YP_005169654.1 378769921 11808446 207685..208653 1 NC_016804.1 Differs from Mb0182 by 1aa, S285N, and from Rv0176 by 3aa, S285N, S290Q, A291S in BCG Pasteur, BCG Tokyo and BCG Mexico; MCE associated transmembrane protein 208653 11808446 BCGMEX_0182 Mycobacterium bovis BCG str. Mexico MCE associated transmembrane protein YP_005169654.1 207685 D 717522 CDS YP_005169655.1 378769922 11808447 208650..209204 1 NC_016804.1 MCE associated protein 209204 11808447 BCGMEX_0183 Mycobacterium bovis BCG str. Mexico MCE associated protein YP_005169655.1 208650 D 717522 CDS YP_005169656.1 378769923 11808448 209171..209905 1 NC_016804.1 MCE associated membrane protein 209905 11808448 BCGMEX_0184 Mycobacterium bovis BCG str. Mexico MCE associated membrane protein YP_005169656.1 209171 D 717522 CDS YP_005169657.1 378769924 11808449 complement(209936..211045) 1 NC_016804.1 Differs from Rv0179c by 1aa, H124R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 211045 lprO 11808449 lprO Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005169657.1 209936 R 717522 CDS YP_005169658.1 378769925 11808450 complement(211125..212483) 1 NC_016804.1 putative transmembrane protein 212483 11808450 BCGMEX_0186c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169658.1 211125 R 717522 CDS YP_005169659.1 378769926 11808451 complement(212510..213244) 1 NC_016804.1 Pirin-like protein 213244 11808451 BCGMEX_0187c Mycobacterium bovis BCG str. Mexico Pirin-like protein YP_005169659.1 212510 R 717522 CDS YP_005169660.1 378769927 11808452 complement(213261..214373) 1 NC_016804.1 RNA polymerase sigma factor 214373 sigG 11808452 sigG Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005169660.1 213261 R 717522 CDS YP_005169661.1 378769928 11808453 214321..215160 1 NC_016804.1 putative lysophospholipase 215160 11808453 BCGMEX_0189 Mycobacterium bovis BCG str. Mexico putative lysophospholipase YP_005169661.1 214321 D 717522 CDS YP_005169662.1 378769929 11808454 215202..215951 1 NC_016804.1 hypothetical protein 215951 11808454 BCGMEX_0190 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169662.1 215202 D 717522 CDS YP_005169663.1 378769930 11808455 215948..216457 1 NC_016804.1 hypothetical protein 216457 11808455 BCGMEX_0191 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169663.1 215948 D 717522 CDS YP_005169664.1 378769931 11808456 216502..218577 1 NC_016804.1 Differs from Mb0192 by 1aa, S504I, and from Rv0186 by 2aa, S504I, R532P in BCG Pasteur, BCG Tokyo and BCG Mexico; putative beta-glucosidase 218577 bglS 11808456 bglS Mycobacterium bovis BCG str. Mexico putative beta-glucosidase YP_005169664.1 216502 D 717522 CDS YP_005169665.1 378769932 11808457 218938..219600 1 NC_016804.1 Differs from Rv0187 and Mb0193 by 1aa, V147A in BCG Pasteur, BCG Tokyo and BCG Mexico; O-methyltransferase 219600 11808457 BCGMEX_0193 Mycobacterium bovis BCG str. Mexico O-methyltransferase YP_005169665.1 218938 D 717522 CDS YP_005169666.1 378769933 11808458 219719..220150 1 NC_016804.1 transmembrane protein 220150 11808458 BCGMEX_0194 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169666.1 219719 D 717522 CDS YP_005169667.1 378769934 11808459 complement(220229..221956) 1 NC_016804.1 dihydroxy-acid dehydratase 221956 ilvD 11808459 ilvD Mycobacterium bovis BCG str. Mexico dihydroxy-acid dehydratase YP_005169667.1 220229 R 717522 CDS YP_005169668.1 378769935 11808460 222104..222394 1 NC_016804.1 hypothetical protein 222394 11808460 BCGMEX_0196 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169668.1 222104 D 717522 CDS YP_005169669.1 378769936 11808461 222522..223763 1 NC_016804.1 putative integral membrane protein 223763 11808461 BCGMEX_0197 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005169669.1 222522 D 717522 CDS YP_005169670.1 378769937 11808462 223840..224898 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0192 and Rv0192A exist as 2 genes with an overlap region. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base insertion (*-g) leads to a single product. Differs from Mb0198 by 1aa, A279V and from Rv0192 by 2aa, P113S, A279V in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 224898 11808462 BCGMEX_0198 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169670.1 223840 D 717522 CDS YP_005169671.1 378769938 11808463 complement(224958..226805) 1 NC_016804.1 Differs from Rv0193c and Mb0199c by 1aa, E417K in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 226805 11808463 BCGMEX_0199c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169671.1 224958 R 717522 CDS YP_005169672.1 378769939 11808464 227112..230696 1 NC_016804.1 Differs from Mb0200 by 1aa, I49V, and from Rv0194 by 2aa, T74M, M223T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative drugs-transport transmembrane ATP-binding protein ABC transporter 230696 11808464 BCGMEX_0200 Mycobacterium bovis BCG str. Mexico putative drugs-transport transmembrane ATP-binding protein ABC transporter YP_005169672.1 227112 D 717522 CDS YP_005169673.1 378769940 11808465 231134..231769 1 NC_016804.1 LuxR family transcriptional regulator 231769 11808465 BCGMEX_0201 Mycobacterium bovis BCG str. Mexico LuxR family transcriptional regulator YP_005169673.1 231134 D 717522 CDS YP_005169674.1 378769941 11808466 231882..232466 1 NC_016804.1 TetR family transcriptional regulator 232466 11808466 BCGMEX_0202 Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005169674.1 231882 D 717522 CDS YP_005169675.1 378769942 11808467 232466..234712 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transversion (T-G) introduces a stop codon that leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (748 aa versus 762 aa). Differs from Rv0197 by 1aa, S378R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 234712 11808467 BCGMEX_0203 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169675.1 232466 D 717522 CDS YP_005169676.1 378769943 11808468 complement(234753..236744) 1 NC_016804.1 putative zinc metalloprotease 236744 11808468 BCGMEX_0204c Mycobacterium bovis BCG str. Mexico putative zinc metalloprotease YP_005169676.1 234753 R 717522 CDS YP_005169677.1 378769944 11808469 236787..237446 1 NC_016804.1 hypothetical protein 237446 11808469 BCGMEX_0205 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169677.1 236787 D 717522 CDS YP_005169678.1 378769945 11808470 237443..238132 1 NC_016804.1 putative transmembrane protein 238132 11808470 BCGMEX_0206 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169678.1 237443 D 717522 CDS YP_005169679.1 378769946 11808471 complement(238129..238632) 1 NC_016804.1 hypothetical protein 238632 11808471 BCGMEX_0207c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169679.1 238129 R 717522 CDS YP_005169680.1 378769947 11808472 complement(238629..241529) 1 NC_016804.1 putative transmembrane transport protein 241529 mmpL11 11808472 mmpL11 Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005169680.1 238629 R 717522 CDS YP_005169681.1 378769948 11808473 241751..242161 1 NC_016804.1 Differs from Rv0203 and Mb0209 by 1aa, T88K in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 242161 11808473 BCGMEX_0209 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169681.1 241751 D 717522 CDS YP_005169682.1 378769949 11808474 complement(242213..243496) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, the presence of a more likely start codon leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (427 aa versus 412 aa). Differs from Rv0204c by 1aa, L321V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 243496 11808474 BCGMEX_0210c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169682.1 242213 R 717522 CDS YP_005169683.1 378769950 11808475 243621..244724 1 NC_016804.1 Differs from Rv0205 by 1aa, R72H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, Tokyo and BCG Mexico; transmembrane protein 244724 11808475 BCGMEX_0211 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169683.1 243621 D 717522 CDS YP_005169684.1 378769951 11808476 complement(244721..247555) 1 NC_016804.1 Differs from Rv0206c by 2aa, I384F, E466D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 247555 mmpL3 11808476 mmpL3 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169684.1 244721 R 717522 CDS YP_005169685.1 378769952 11808477 complement(247621..248349) 1 NC_016804.1 hypothetical protein 248349 11808477 BCGMEX_0213c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169685.1 247621 R 717522 CDS YP_005169686.1 378769953 11808478 complement(248352..249143) 1 NC_016804.1 tRNA (guanine46-N7-)-methyltransferase 249143 11808478 BCGMEX_0214c Mycobacterium bovis BCG str. Mexico tRNA (guanine46-N7-)-methyltransferase YP_005169686.1 248352 R 717522 CDS YP_005169687.1 378769954 11808479 249275..250360 1 NC_016804.1 Differs from Rv0209 by 1aa, A162V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 250360 11808479 BCGMEX_0215 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169687.1 249275 D 717522 CDS YP_005169688.1 378769955 11808480 250357..251835 1 NC_016804.1 Differs from Rv0210 by 1aa, T486A in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 251835 11808480 BCGMEX_0216 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169688.1 250357 D 717522 CDS YP_005169689.1 378769956 11808481 252019..253839 1 NC_016804.1 phosphoenolpyruvate carboxykinase 253839 pckA 11808481 pckA Mycobacterium bovis BCG str. Mexico phosphoenolpyruvate carboxykinase YP_005169689.1 252019 D 717522 CDS YP_005169690.1 378769957 11808482 complement(253906..254877) 1 NC_016804.1 putative transcriptional regulatory protein, AsnC-family 254877 nadR 11808482 nadR Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, AsnC-family YP_005169690.1 253906 R 717522 CDS YP_005169691.1 378769958 11808483 complement(254874..256187) 1 NC_016804.1 putative methyltransferase 256187 11808483 BCGMEX_0219c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005169691.1 254874 R 717522 CDS YP_005169692.1 378769959 11808484 256301..257914 1 NC_016804.1 Differs from Rv0214 by 1aa, A40G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, Tokyo and BCG Mexico; putative fatty-acid-CoA ligase fadD4 257914 fadD4 11808484 fadD4 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase fadD4 YP_005169692.1 256301 D 717522 CDS YP_005169693.1 378769960 11808485 complement(257956..259122) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 29 bp insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (388 aa versus 357 aa). Differs from Mb0221c by 1aa, S361A in BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA dehydrogenase 259122 fadE3 11808485 fadE3 Mycobacterium bovis BCG str. Mexico acyl-CoA dehydrogenase YP_005169693.1 257956 R 717522 CDS YP_005169694.1 378769961 11808486 259179..260192 1 NC_016804.1 hypothetical protein 260192 11808486 BCGMEX_0222 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169694.1 259179 D 717522 CDS YP_005169695.1 378769962 11808487 complement(260189..261097) 1 NC_016804.1 Differs from Rv0217c by 1aa T184P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative esterase 261097 lipW 11808487 lipW Mycobacterium bovis BCG str. Mexico putative esterase YP_005169695.1 260189 R 717522 CDS YP_005169696.1 378769963 11808488 261190..262518 1 NC_016804.1 Differs from Rv0218 by 2aa, R316C, N413D in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; transmembrane protein 262518 11808488 BCGMEX_0224 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169696.1 261190 D 717522 CDS YP_005169697.1 378769964 11808489 262520..263068 1 NC_016804.1 transmembrane protein 263068 11808489 BCGMEX_0225 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169697.1 262520 D 717522 CDS YP_005169698.1 378769965 11808490 263078..264319 1 NC_016804.1 putative esterase 264319 lipC 11808490 lipC Mycobacterium bovis BCG str. Mexico putative esterase YP_005169698.1 263078 D 717522 CDS YP_005169699.1 378769966 11808491 264333..265106 1 NC_016804.1 In Mycobacterium bovis and Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, RD10, a 1902 bp deletion leads to a shorter product with a different COOH part, compared to its homolog in Mycobacterium tuberculosis strain H37Rv (257 aa versus 469 aa). It also leads to the deletion of the next protein, echA1 (Rv0222) in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 265106 11808491 BCGMEX_0227 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169699.1 264333 D 717522 CDS YP_005169700.1 378769967 11808492 complement(264972..265781) 1 NC_016804.1 In Mycobacterium bovis strain AF2122/97, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, RD10, a 1902 bp deletion, compared to Mycobacterium tuberculosis H37Rv, truncates Rv0221c and Rv0223c and removes Rv0222c. In Mycobacterium bovis BCG Pasteur and BCG Tokyo, a single base deletion (*-C) splits gene into two parts compared to its homologs in Mycobacterium tuberculosis strain H37Rv and Mycobacterium bovis AF2122/97 (116 aa and 269 aa, versus 487 aa and 385 aa, respectively). Deletion in Mycobacterium bovis, bovis BCG Pasteur, BCG Tokyo and BCG Mexico of region RD10 leads to a different COOH part compared to Mycobacterium tuberculosis strain H37Rv. Maybe pseudogene.; putative aldehyde dehydrogenase 265781 11808492 BCGMEX_0228c Mycobacterium bovis BCG str. Mexico putative aldehyde dehydrogenase YP_005169700.1 264972 R 717522 CDS YP_005169701.1 378769968 11808493 complement(265778..266128) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base deletion(*-C) splits gene into two parts compared to its homologs in Mycobacterium tuberculosis strain H37Rv and Mycobacterium bovis AF2122/97 (116 aa and 269 aa, versus 487 aa and 385 aa, respectively). May be pseudogene; putative aldehyde dehydrogenase 266128 11808493 BCGMEX_0229c Mycobacterium bovis BCG str. Mexico putative aldehyde dehydrogenase YP_005169701.1 265778 R 717522 CDS YP_005169702.1 378769969 11808494 complement(266227..266991) 1 NC_016804.1 Differs from Rv0224c by 1aa, L117F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative methyltransferase 266991 11808494 BCGMEX_0230c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005169702.1 266227 R 717522 CDS YP_005169703.1 378769970 11808495 267027..268181 1 NC_016804.1 glycosyltransferase 268181 11808495 BCGMEX_0231 Mycobacterium bovis BCG str. Mexico glycosyltransferase YP_005169703.1 267027 D 717522 CDS YP_005169704.1 378769971 11808496 complement(268198..269928) 1 NC_016804.1 transmembrane protein 269928 11808496 BCGMEX_0232c Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169704.1 268198 R 717522 CDS YP_005169705.1 378769972 11808497 complement(269938..271203) 1 NC_016804.1 Differs from Rv0227c by 1aa, R29S, and from Mb0232c by 1aa, S392N in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 271203 11808497 BCGMEX_0233c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169705.1 269938 R 717522 CDS YP_005169706.1 378769973 11808498 271419..272642 1 NC_016804.1 acyltransferase 272642 11808498 BCGMEX_0234 Mycobacterium bovis BCG str. Mexico acyltransferase YP_005169706.1 271419 D 717522 CDS YP_005169707.1 378769974 11808499 complement(272670..273350) 1 NC_016804.1 hypothetical protein 273350 11808499 BCGMEX_0235c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169707.1 272670 R 717522 CDS YP_005169708.1 378769975 11808500 complement(273347..274327) 1 NC_016804.1 Differs from Rv0230c by 1aa, E199D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phosphotriesterase-like protein 274327 php 11808500 php Mycobacterium bovis BCG str. Mexico phosphotriesterase-like protein YP_005169708.1 273347 R 717522 CDS YP_005169709.1 378769976 11808501 274422..276128 1 NC_016804.1 acyl-CoA dehydrogenase 276128 fadE4 11808501 fadE4 Mycobacterium bovis BCG str. Mexico acyl-CoA dehydrogenase YP_005169709.1 274422 D 717522 CDS YP_005169710.1 378769977 11808502 276263..276952 1 NC_016804.1 TetR family transcriptional regulator 276952 11808502 BCGMEX_0238 Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005169710.1 276263 D 717522 CDS YP_005169711.1 378769978 11808503 276949..277893 1 NC_016804.1 Differs from Rv0233 by 1aa, D33H in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ribonucleoside-diphosphate reductase subunit beta 277893 nrdB 11808503 nrdB Mycobacterium bovis BCG str. Mexico ribonucleoside-diphosphate reductase subunit beta YP_005169711.1 276949 D 717522 CDS YP_005169712.1 378769979 11808504 complement(277969..279504) 1 NC_016804.1 Succinate-semialdehyde dehydrogenase [NADP+] 1 279504 gabD1 11808504 gabD1 Mycobacterium bovis BCG str. Mexico Succinate-semialdehyde dehydrogenase [NADP+] 1 YP_005169712.1 277969 R 717522 CDS YP_005169713.1 378769980 11808505 complement(279530..280978) 1 NC_016804.1 putative transmembrane protein 280978 11808505 BCGMEX_0241c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169713.1 279530 R 717522 CDS YP_005169714.1 378769981 11808506 complement(281013..285215) 1 NC_016804.1 Differs from Rv0236c by 3aa, V412M, A990T, G1080S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; transmembrane protein 285215 11808506 BCGMEX_0242c Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169714.1 281013 R 717522 CDS YP_005169715.1 378769982 11808507 complement(285262..285435) 1 NC_016804.1 Small secreted protein 285435 11808507 BCGMEX_0243c Mycobacterium bovis BCG str. Mexico Small secreted protein YP_005169715.1 285262 R 717522 CDS YP_005169716.1 378769983 11808508 285550..286716 1 NC_016804.1 Differs from Rv0237 by 1aa, L129V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 286716 lpqI 11808508 lpqI Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005169716.1 285550 D 717522 CDS YP_005169717.1 378769984 11808509 286792..287406 1 NC_016804.1 TetR family transcriptional regulator 287406 11808509 BCGMEX_0245 Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005169717.1 286792 D 717522 CDS YP_005169718.1 378769985 11808510 287468..287701 1 NC_016804.1 hypothetical protein 287701 11808510 BCGMEX_0246 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169718.1 287468 D 717522 CDS YP_005169719.1 378769986 11808511 287709..288146 1 NC_016804.1 Differs from Rv0240 by 1aa, S31A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 288146 11808511 BCGMEX_0247 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169719.1 287709 D 717522 CDS YP_005169720.1 378769987 11808512 complement(288176..289018) 1 NC_016804.1 hypothetical protein 289018 11808512 BCGMEX_0248c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169720.1 288176 R 717522 CDS YP_005169721.1 378769988 11808513 complement(289029..290393) 1 NC_016804.1 3-oxoacyl-ACP reductase 290393 fabG4 11808513 fabG4 Mycobacterium bovis BCG str. Mexico 3-oxoacyl-ACP reductase YP_005169721.1 289029 R 717522 CDS YP_005169722.1 378769989 11808514 290535..291857 1 NC_016804.1 acetyl-CoA acyltransferase 291857 fadA2 11808514 fadA2 Mycobacterium bovis BCG str. Mexico acetyl-CoA acyltransferase YP_005169722.1 290535 D 717522 CDS YP_005169723.1 378769990 11808515 complement(292163..293998) 1 NC_016804.1 Differs from Mb0250c by 1aa, N503D and from Rv0244c by 3aa, R394K, A479E, N503D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyl- CoA dehydrogenase 293998 fadE5 11808515 fadE5 Mycobacterium bovis BCG str. Mexico putative acyl- CoA dehydrogenase YP_005169723.1 292163 R 717522 CDS YP_005169724.1 378769991 11808516 294370..294858 1 NC_016804.1 putative oxidoreductase 294858 11808516 BCGMEX_0252 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169724.1 294370 D 717522 CDS YP_005169725.1 378769992 11808517 295174..296484 1 NC_016804.1 Differs from Mb0252 by 1aa, A129V in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; integral membrane protein 296484 11808517 BCGMEX_0253 Mycobacterium bovis BCG str. Mexico integral membrane protein YP_005169725.1 295174 D 717522 CDS YP_005169726.1 378769993 11808518 complement(296481..297227) 1 NC_016804.1 Fumarate reductase iron-sulfur subunit 297227 11808518 BCGMEX_0254c Mycobacterium bovis BCG str. Mexico Fumarate reductase iron-sulfur subunit YP_005169726.1 296481 R 717522 CDS YP_005169727.1 378769994 11808519 complement(297228..299168) 1 NC_016804.1 Succinate dehydrogenase flavoprotein subunit 299168 sdhA 11808519 sdhA Mycobacterium bovis BCG str. Mexico Succinate dehydrogenase flavoprotein subunit YP_005169727.1 297228 R 717522 CDS YP_005169728.1 378769995 11808520 complement(299199..300020) 1 NC_016804.1 putative succinate dehydrogenase membrane anchor subunit 300020 11808520 BCGMEX_0256c Mycobacterium bovis BCG str. Mexico putative succinate dehydrogenase membrane anchor subunit YP_005169728.1 299199 R 717522 CDS YP_005169729.1 378769996 11808521 complement(300100..300393) 1 NC_016804.1 hypothetical protein 300393 11808521 BCGMEX_0257c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169729.1 300100 R 717522 CDS YP_005169730.1 378769997 11808522 complement(300538..301017) 1 NC_016804.1 heat shock protein 301017 hsp 11808522 hsp Mycobacterium bovis BCG str. Mexico heat shock protein YP_005169730.1 300538 R 717522 CDS YP_005169731.1 378769998 11808523 301231..303792 1 NC_016804.1 nitrite reductase [NAD(P)H] large subunit 303792 nirB 11808523 nirB Mycobacterium bovis BCG str. Mexico nitrite reductase [NAD(P)H] large subunit YP_005169731.1 301231 D 717522 CDS YP_005169732.1 378769999 11808524 303818..304174 1 NC_016804.1 nitrite reductase [NAD(P)H] small subunit 304174 nirD 11808524 nirD Mycobacterium bovis BCG str. Mexico nitrite reductase [NAD(P)H] small subunit YP_005169732.1 303818 D 717522 CDS YP_005169733.1 378770000 11808525 complement(304190..304714) 1 NC_016804.1 putative bifunctional cobalamin biosynthesis protein 304714 cobU 11808525 cobU Mycobacterium bovis BCG str. Mexico putative bifunctional cobalamin biosynthesis protein YP_005169733.1 304190 R 717522 CDS YP_005169734.1 378770001 11808526 complement(304739..306223) 1 NC_016804.1 cobyric acid synthase 306223 cobQ1 11808526 cobQ1 Mycobacterium bovis BCG str. Mexico cobyric acid synthase YP_005169734.1 304739 R 717522 CDS YP_005169735.1 378770002 11808527 complement(306242..307912) 1 NC_016804.1 PPE family protein 307912 PPE2 11808527 PPE2 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169735.1 306242 R 717522 CDS YP_005169736.1 378770003 11808528 complement(308302..308634) 1 NC_016804.1 hypothetical protein 308634 11808528 BCGMEX_0264c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169736.1 308302 R 717522 CDS YP_005169737.1 378770004 11808529 complement(308659..309114) 1 NC_016804.1 hypothetical protein 309114 11808529 BCGMEX_0265c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169737.1 308659 R 717522 CDS YP_005169738.1 378770005 11808530 complement(309139..309882) 1 NC_016804.1 Differs from Rv0259c by 1aa, V182A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 309882 11808530 BCGMEX_0266c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169738.1 309139 R 717522 CDS YP_005169739.1 378770006 11808531 complement(309879..311024) 1 NC_016804.1 Response regulator domain protein; Uroporphyrinogen-III synthetase 311024 11808531 BCGMEX_0267c Mycobacterium bovis BCG str. Mexico Uroporphyrinogen-III synthetase YP_005169739.1 309879 R 717522 CDS YP_005169740.1 378770007 11808532 complement(311124..312533) 1 NC_016804.1 putative integral membrane nitrite extrusion protein 312533 narK3 11808532 narK3 Mycobacterium bovis BCG str. Mexico putative integral membrane nitrite extrusion protein YP_005169740.1 311124 R 717522 CDS YP_005169741.1 378770008 11808533 complement(312674..313219) 1 NC_016804.1 aminoglycoside 2'-N-acetyltransferase 313219 aac 11808533 aac Mycobacterium bovis BCG str. Mexico aminoglycoside 2'-N-acetyltransferase YP_005169741.1 312674 R 717522 CDS YP_005169742.1 378770009 11808534 complement(313229..314131) 1 NC_016804.1 hypothetical protein 314131 11808534 BCGMEX_0270c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169742.1 313229 R 717522 CDS YP_005169743.1 378770010 11808535 complement(314148..314780) 1 NC_016804.1 hypothetical protein 314780 11808535 BCGMEX_0271c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169743.1 314148 R 717522 CDS YP_005169744.1 378770011 11808536 complement(314876..315868) 1 NC_016804.1 Differs from Rv0265c and Mb0271c by 1aa, C313Y in BCG Pasteur, BCG Tokyo and BCG Mexico; putative periplasmic iron-transport lipoprotein 315868 11808536 BCGMEX_0272c Mycobacterium bovis BCG str. Mexico putative periplasmic iron-transport lipoprotein YP_005169744.1 314876 R 717522 CDS YP_005169745.1 378770012 11808537 complement(315890..319519) 1 NC_016804.1 putative 5-oxoprolinase 319519 oplA 11808537 oplA Mycobacterium bovis BCG str. Mexico putative 5-oxoprolinase YP_005169745.1 315890 R 717522 CDS YP_005169746.1 378770013 11808538 319696..321087 1 NC_016804.1 putative integral membrane nitrite extrusion protein 321087 narU 11808538 narU Mycobacterium bovis BCG str. Mexico putative integral membrane nitrite extrusion protein YP_005169746.1 319696 D 717522 CDS YP_005169747.1 378770014 11808539 complement(321129..321638) 1 NC_016804.1 hypothetical protein 321638 11808539 BCGMEX_0275c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169747.1 321129 R 717522 CDS YP_005169748.1 378770015 11808540 complement(321703..322896) 1 NC_016804.1 hypothetical protein 322896 11808540 BCGMEX_0276c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169748.1 321703 R 717522 CDS YP_005169749.1 378770016 11808541 322932..324614 1 NC_016804.1 Differs from Rv0270 and Mb0276 by 1aa, E112D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative fatty-acid-CoA ligase 324614 fadD2 11808541 fadD2 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005169749.1 322932 D 717522 CDS YP_005169750.1 378770017 11808542 complement(324631..326826) 1 NC_016804.1 putative acyl-CoA dehydrogenase 326826 fadE6 11808542 fadE6 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005169750.1 324631 R 717522 CDS YP_005169751.1 378770018 11808543 complement(326940..328073) 1 NC_016804.1 Differs from Mb0278c by 1aa, P164L in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 328073 11808543 BCGMEX_0279c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169751.1 326940 R 717522 CDS YP_005169752.1 378770019 11808544 complement(328070..328690) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 328690 11808544 BCGMEX_0280c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005169752.1 328070 R 717522 CDS YP_005169753.1 378770020 11808545 328787..329368 1 NC_016804.1 hypothetical protein 329368 11808545 BCGMEX_0281 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169753.1 328787 D 717522 CDS YP_005169754.1 378770021 11808546 complement(329298..330023) 1 NC_016804.1 Differs from Rv0275c by 1aa, L24S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, TetR family 330023 11808546 BCGMEX_0282c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005169754.1 329298 R 717522 CDS YP_005169755.1 378770022 11808547 330113..331033 1 NC_016804.1 hypothetical protein 331033 11808547 BCGMEX_0283 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169755.1 330113 D 717522 CDS YP_005169756.1 378770023 11808548 complement(331073..331501) 1 NC_016804.1 hypothetical protein 331501 11808548 BCGMEX_0284c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169756.1 331073 R 717522 CDS YP_005169757.1 378770024 11808549 complement(331525..331782) 1 NC_016804.1 Differs by 1 aa, Q24* from Rv0227A and Mb0351A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 331782 11808549 BCGMEX_0285c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169757.1 331525 R 717522 CDS YP_005169758.1 378770025 11808551 complement(331867..334617) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS3 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a large insertion leads to an extra copy of PE_PGRS3. Also, a frameshift due to single base deletion (T-*), splits this extra copy of PE_PGRS3 into 2 parts, PE_PGRS3a and PE_PGRS3b. Also differs from Mb0285c by an insertion of 144bp.; PE-PGRS family protein 334617 PE_PGRS3a 11808551 PE_PGRS3a Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005169758.1 331867 R 717522 CDS YP_005169759.1 378770026 11808552 complement(334881..337580) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a insertion of 66 bp lead to a longer product than to the homolog Mycobacterium bovis (899 aa versus 877 aa). In Mycobacterium bovis, 2 deletions, one of 18 bp and the other of 66 bp, and part of a 2780 bp insertion , leads to a shorter product with a different 3' end compared to its homolog in Mycobacterium tuberculosis strain H37Rv (877 aa versus 957 aa); PE-PGRS family protein 337580 PE_PGRS3 11808552 PE_PGRS3 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005169759.1 334881 R 717522 CDS YP_005169760.1 378770027 11808553 complement(337830..340334) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, 2 insertion seach of 9 bp and a deletion of 9 bp, lead to a longer product compared to its homolog in Mycobacterium bovis (834 aa versus 831 aa). In Mycobacterium bovis, 2 deletions each of 9 bp , leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (831 aa versus 837 aa); PE-PGRS family protein 340334 PE_PGRS4 11808553 PE_PGRS4 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005169760.1 337830 R 717522 CDS YP_005169761.1 378770028 11808554 340625..342235 1 NC_016804.1 Differs from Rv0280 by 1 aa P337S in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 342235 PPE3 11808554 PPE3 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169761.1 340625 D 717522 CDS YP_005169762.1 378770029 11808555 342259..343167 1 NC_016804.1 putative S-adenosyl-L-methionine-dependent methyltransferase 343167 11808555 BCGMEX_0291 Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005169762.1 342259 D 717522 CDS YP_005169763.1 378770030 11808556 343392..345287 1 NC_016804.1 Differs from Rv0282 by 1aa, A6E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ESX-3 secretion system protein 345287 eccA3 11808556 eccA3 Mycobacterium bovis BCG str. Mexico putative ESX-3 secretion system protein YP_005169763.1 343392 D 717522 CDS YP_005169764.1 378770031 11808557 345284..346900 1 NC_016804.1 putative ESX-3 secretion system protein 346900 eccB3 11808557 eccB3 Mycobacterium bovis BCG str. Mexico putative ESX-3 secretion system protein YP_005169764.1 345284 D 717522 CDS YP_005169765.1 378770032 11808558 346897..350889 1 NC_016804.1 putative ESX-3 secretion system protein 350889 eccC3 11808558 eccC3 Mycobacterium bovis BCG str. Mexico putative ESX-3 secretion system protein YP_005169765.1 346897 D 717522 CDS YP_005169766.1 378770033 11808559 350886..351194 1 NC_016804.1 PE family protein 351194 PE5 11808559 PE5 Mycobacterium bovis BCG str. Mexico PE family protein YP_005169766.1 350886 D 717522 CDS YP_005169767.1 378770034 11808560 351197..352738 1 NC_016804.1 PPE family protein 352738 PPE4 11808560 PPE4 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169767.1 351197 D 717522 CDS YP_005169768.1 378770035 11808561 352787..353080 1 NC_016804.1 hypothetical protein 353080 esxG 11808561 esxG Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169768.1 352787 D 717522 CDS YP_005169769.1 378770036 11808562 353110..353400 1 NC_016804.1 ESAT-6-like protein 353400 esxH 11808562 esxH Mycobacterium bovis BCG str. Mexico ESAT-6-like protein YP_005169769.1 353110 D 717522 CDS YP_005169770.1 378770037 11808563 353411..354298 1 NC_016804.1 putative ESX-3 secretion-associated protein EspG3 354298 espG3 11808563 espG3 Mycobacterium bovis BCG str. Mexico putative ESX-3 secretion-associated protein EspG3 YP_005169770.1 353411 D 717522 CDS YP_005169771.1 378770038 11808564 354345..355763 1 NC_016804.1 Differs from Rv0290 by 1aa, T400A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 355763 11808564 BCGMEX_0300 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169771.1 354345 D 717522 CDS YP_005169772.1 378770039 11808565 355760..357145 1 NC_016804.1 putative protease 357145 11808565 BCGMEX_0301 Mycobacterium bovis BCG str. Mexico putative protease YP_005169772.1 355760 D 717522 CDS YP_005169773.1 378770040 11808566 357142..358137 1 NC_016804.1 Differs from Rv0292 by 1aa, D217N in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 358137 11808566 BCGMEX_0302 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169773.1 357142 D 717522 CDS YP_005169774.1 378770041 11808567 complement(358124..359326) 1 NC_016804.1 Differs from Rv0293c and Mb0301c by 1aa, S263G in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 359326 11808567 BCGMEX_0303c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169774.1 358124 R 717522 CDS YP_005169775.1 378770042 11808568 359433..360218 1 NC_016804.1 Trans-aconitate 2-methyltransferase 360218 tam 11808568 tam Mycobacterium bovis BCG str. Mexico Trans-aconitate 2-methyltransferase YP_005169775.1 359433 D 717522 CDS YP_005169776.1 378770043 11808569 complement(360207..361010) 1 NC_016804.1 hypothetical protein 361010 11808569 BCGMEX_0305c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169776.1 360207 R 717522 CDS YP_005169777.1 378770044 11808570 complement(361020..362417) 1 NC_016804.1 putative sulfatase 362417 11808570 BCGMEX_0306c Mycobacterium bovis BCG str. Mexico putative sulfatase YP_005169777.1 361020 R 717522 CDS YP_005169778.1 378770045 11808571 362596..364416 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 45 bp in-frame insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (606 aa versus 591 aa); PE-PGRS family protein 364416 PE_PGRS5 11808571 PE_PGRS5 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005169778.1 362596 D 717522 CDS YP_005169779.1 378770046 11808572 364559..364786 1 NC_016804.1 hypothetical protein 364786 11808572 BCGMEX_0308 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169779.1 364559 D 717522 CDS YP_005169780.1 378770047 11808573 364783..365085 1 NC_016804.1 Differs from Mb0307 by 1aa, S13N in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 365085 11808573 BCGMEX_0309 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169780.1 364783 D 717522 CDS YP_005169781.1 378770048 11808574 365133..365354 1 NC_016804.1 hypothetical protein 365354 11808574 BCGMEX_0310 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169781.1 365133 D 717522 CDS YP_005169782.1 378770049 11808575 365351..365776 1 NC_016804.1 hypothetical protein 365776 11808575 BCGMEX_0311 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169782.1 365351 D 717522 CDS YP_005169783.1 378770050 11808576 365913..366545 1 NC_016804.1 Differs from Mb0310 by 1aa A124V in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, TetR family 366545 11808576 BCGMEX_0312 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005169783.1 365913 D 717522 CDS YP_005169784.1 378770051 11808577 366542..367450 1 NC_016804.1 putative dehydrogenase/reductase 367450 11808577 BCGMEX_0313 Mycobacterium bovis BCG str. Mexico putative dehydrogenase/reductase YP_005169784.1 366542 D 717522 CDS YP_005169785.1 378770052 11808578 complement(367458..370901) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE5 and PPE6 exist as separate genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion (G-*) leads to a shorter CDS (Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico) Equivalent to the 3' end of Rv0304c/PPE5. Differs from Rv0304c by 3aa, S481G, F708S, A955T, and 5 codon in-frame deletion at position 503 in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 370901 PPE5 11808578 PPE5 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169785.1 367458 R 717522 CDS YP_005169786.1 378770053 11808579 complement(371045..376972) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE5 and PPE6 exist as separate genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base deletion (T-*) resulting in the absence of a stop codon leads to a longer product. The second part of this CDS shares homology with the 5' end of Rv0304c/PPE5. Differs from Mb0313c by in-frame deletion of 10 codons in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 376972 PPE6 11808579 PPE6 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169786.1 371045 R 717522 CDS YP_005169787.1 378770054 11808580 377175..377846 1 NC_016804.1 putative oxidoreductase 377846 11808580 BCGMEX_0316 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169787.1 377175 D 717522 CDS YP_005169788.1 378770055 11808581 complement(377834..378316) 1 NC_016804.1 hypothetical protein 378316 11808581 BCGMEX_0317c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169788.1 377834 R 717522 CDS YP_005169789.1 378770056 11808582 378374..379090 1 NC_016804.1 integral membrane protein 379090 11808582 BCGMEX_0318 Mycobacterium bovis BCG str. Mexico integral membrane protein YP_005169789.1 378374 D 717522 CDS YP_005169790.1 378770057 11808583 379192..379848 1 NC_016804.1 hypothetical protein 379848 11808583 BCGMEX_0319 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169790.1 379192 D 717522 CDS YP_005169791.1 378770058 11808584 complement(379918..380409) 1 NC_016804.1 hypothetical protein 380409 11808584 BCGMEX_0320c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169791.1 379918 R 717522 CDS YP_005169792.1 378770059 11808585 380433..381662 1 NC_016804.1 hypothetical protein 381662 11808585 BCGMEX_0321 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169792.1 380433 D 717522 CDS YP_005169793.1 378770060 11808586 381817..383679 1 NC_016804.1 Differs from Rv0312 by 2aa, G159S, L563P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative proline and threonine rich protein 383679 11808586 BCGMEX_0322 Mycobacterium bovis BCG str. Mexico putative proline and threonine rich protein YP_005169793.1 381817 D 717522 CDS YP_005169794.1 378770061 11808587 383751..384137 1 NC_016804.1 hypothetical protein 384137 11808587 BCGMEX_0323 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169794.1 383751 D 717522 CDS YP_005169795.1 378770062 11808588 complement(384140..384802) 1 NC_016804.1 Differs from Rv0314c by 1aa, A184V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 384802 11808588 BCGMEX_0324c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169795.1 384140 R 717522 CDS YP_005169796.1 378770063 11808589 384863..385747 1 NC_016804.1 Differs from Rv0315 by 1aa, T260K in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative beta-1,3-glucanase 385747 11808589 BCGMEX_0325 Mycobacterium bovis BCG str. Mexico putative beta-1,3-glucanase YP_005169796.1 384863 D 717522 CDS YP_005169797.1 378770064 11808590 385796..386410 1 NC_016804.1 muconolactone isomerase 386410 11808590 BCGMEX_0326 Mycobacterium bovis BCG str. Mexico muconolactone isomerase YP_005169797.1 385796 D 717522 CDS YP_005169798.1 378770065 11808591 complement(386434..387204) 1 NC_016804.1 putative glycerophosphoryl diester phosphodiesterase 387204 glpQ2 11808591 glpQ2 Mycobacterium bovis BCG str. Mexico putative glycerophosphoryl diester phosphodiesterase YP_005169798.1 386434 R 717522 CDS YP_005169799.1 378770066 11808593 complement(387566..388360) 1 NC_016804.1 Differs from Rv0318c by 1aa, A223G in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 388360 11808593 BCGMEX_0328c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005169799.1 387566 R 717522 CDS YP_005169800.1 378770067 11808594 388409..389077 1 NC_016804.1 Pyrrolidone-carboxylate peptidase 389077 pcp 11808594 pcp Mycobacterium bovis BCG str. Mexico Pyrrolidone-carboxylate peptidase YP_005169800.1 388409 D 717522 CDS YP_005169801.1 378770068 11808595 389149..389811 1 NC_016804.1 hypothetical protein 389811 11808595 BCGMEX_0330 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169801.1 389149 D 717522 CDS YP_005169802.1 378770069 11808596 389843..390415 1 NC_016804.1 Differs from Rv0321 by 1aa, C183Y in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Deoxycytidine triphosphate deaminase 390415 dcd 11808596 dcd Mycobacterium bovis BCG str. Mexico Deoxycytidine triphosphate deaminase YP_005169802.1 389843 D 717522 CDS YP_005169803.1 378770070 11808597 390521..391852 1 NC_016804.1 putative UDP-glucose 6-dehydrogenase 391852 udgA 11808597 udgA Mycobacterium bovis BCG str. Mexico putative UDP-glucose 6-dehydrogenase YP_005169803.1 390521 D 717522 CDS YP_005169804.1 378770071 11808598 complement(391841..392512) 1 NC_016804.1 Differs from Rv0323c by 1aa, G142S in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 392512 11808598 BCGMEX_0333c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169804.1 391841 R 717522 CDS YP_005169805.1 378770072 11808599 392613..393293 1 NC_016804.1 Differs from Rv0324 by 1aa, A168T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, ArsR family 393293 11808599 BCGMEX_0334 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, ArsR family YP_005169805.1 392613 D 717522 CDS YP_005169806.1 378770073 11808600 393300..393989 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0325 and Rv0326 exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, the absence of a stop codon between Rv0325 and Rv0326 due to a single base transition (T-C) leads to single product; hypothetical protein 393989 11808600 BCGMEX_0335 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169806.1 393300 D 717522 CDS YP_005169807.1 378770074 11808601 complement(393957..395306) 1 NC_016804.1 Differs from Rv0327c by 1aa, Y100H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytochrome P450 135A1 395306 cyp135A1 11808601 cyp135A1 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 135A1 YP_005169807.1 393957 R 717522 CDS YP_005169808.1 378770075 11808602 395372..395974 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 395974 11808602 BCGMEX_0337 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005169808.1 395372 D 717522 CDS YP_005169809.1 378770076 11808603 complement(395955..396581) 1 NC_016804.1 Differs from Rv0329c by 1aa, S129W in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 396581 11808603 BCGMEX_0338c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169809.1 395955 R 717522 CDS YP_005169810.1 378770077 11808604 complement(396608..397348) 1 NC_016804.1 hypothetical protein 397348 11808604 BCGMEX_0339c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169810.1 396608 R 717522 CDS YP_005169811.1 378770078 11808605 397462..398628 1 NC_016804.1 putative dehydrogenase/reductase 398628 11808605 BCGMEX_0340 Mycobacterium bovis BCG str. Mexico putative dehydrogenase/reductase YP_005169811.1 397462 D 717522 CDS YP_005169812.1 378770079 11808606 398703..399488 1 NC_016804.1 Differs from Rv0332 by 1aa, G198E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 399488 11808606 BCGMEX_0341 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169812.1 398703 D 717522 CDS YP_005169813.1 378770080 11808607 399515..399889 1 NC_016804.1 hypothetical protein 399889 11808607 BCGMEX_0342 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169813.1 399515 D 717522 CDS YP_005169814.1 378770081 11808608 399919..400785 1 NC_016804.1 glucose-1-phosphate thymidylyltransferase 400785 rmlA 11808608 rmlA Mycobacterium bovis BCG str. Mexico glucose-1-phosphate thymidylyltransferase YP_005169814.1 399919 D 717522 CDS YP_005169815.1 378770082 11808609 complement(400796..401311) 1 NC_016804.1 Differs from Rv0335c and Mb0340 by 1aa P131T in BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 401311 PE6 11808609 PE6 Mycobacterium bovis BCG str. Mexico PE family protein YP_005169815.1 400796 R 717522 CDS YP_005169816.1 378770083 11808610 401453..402964 1 NC_016804.1 Differs from Rv0336 by 1aa, H496P in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 402964 11808610 BCGMEX_0345 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169816.1 401453 D 717522 CDS YP_005169817.1 378770084 11808611 complement(403134..404423) 1 NC_016804.1 aspartate aminotransferase 404423 aspC 11808611 aspC Mycobacterium bovis BCG str. Mexico aspartate aminotransferase YP_005169817.1 403134 R 717522 CDS YP_005169818.1 378770085 11808612 complement(404454..407102) 1 NC_016804.1 Differs from Rv0338c by 2aa, G506R, V621A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative iron-sulfur-binding reductase 407102 11808612 BCGMEX_0347c Mycobacterium bovis BCG str. Mexico putative iron-sulfur-binding reductase YP_005169818.1 404454 R 717522 CDS YP_005169819.1 378770086 11808613 complement(407211..409709) 1 NC_016804.1 putative transcriptional regulatory protein 409709 11808613 BCGMEX_0348c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005169819.1 407211 R 717522 CDS YP_005169820.1 378770087 11808614 409895..410434 1 NC_016804.1 hypothetical protein 410434 11808614 BCGMEX_0349 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169820.1 409895 D 717522 CDS YP_005169821.1 378770088 11808615 410623..412062 1 NC_016804.1 isoniazid-inducible protein 412062 iniB 11808615 iniB Mycobacterium bovis BCG str. Mexico isoniazid-inducible protein YP_005169821.1 410623 D 717522 CDS YP_005169822.1 378770089 11808616 412099..414021 1 NC_016804.1 Differs from by 2aa, S88N, Q481H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; isoniazid-inducible protein iniA 414021 iniA 11808616 iniA Mycobacterium bovis BCG str. Mexico isoniazid-inducible protein iniA YP_005169822.1 412099 D 717522 CDS YP_005169823.1 378770090 11808617 414018..415499 1 NC_016804.1 isoniazid-inducible protein iniC 415499 iniC 11808617 iniC Mycobacterium bovis BCG str. Mexico isoniazid-inducible protein iniC YP_005169823.1 414018 D 717522 CDS YP_005169824.1 378770091 11808618 complement(415642..416202) 1 NC_016804.1 Lipoprotein 416202 lpqJ 11808618 lpqJ Mycobacterium bovis BCG str. Mexico Lipoprotein YP_005169824.1 415642 R 717522 CDS YP_005169825.1 378770092 11808619 416311..416721 1 NC_016804.1 In Mycobacterium bovis, a frameshift due to a single base deletion (A-*) leads to a shorter product with a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 416721 11808619 BCGMEX_0354 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169825.1 416311 D 717522 CDS YP_005169826.1 378770093 11808620 complement(416763..418226) 1 NC_016804.1 putative L-asparagine permease 418226 ansP2 11808620 ansP2 Mycobacterium bovis BCG str. Mexico putative L-asparagine permease YP_005169826.1 416763 R 717522 CDS YP_005169827.1 378770094 11808621 418565..419551 1 NC_016804.1 membrane protein 419551 11808621 BCGMEX_0356 Mycobacterium bovis BCG str. Mexico membrane protein YP_005169827.1 418565 D 717522 CDS YP_005169828.1 378770095 11808622 419554..420207 1 NC_016804.1 putative transcriptional regulatory protein 420207 11808622 BCGMEX_0357 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005169828.1 419554 D 717522 CDS YP_005169829.1 378770096 11808623 420210..420869 1 NC_016804.1 hypothetical protein 420869 11808623 BCGMEX_0358 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169829.1 420210 D 717522 CDS YP_005169830.1 378770097 11808624 421096..422973 1 NC_016804.1 putative chaperone protein 422973 dnaK 11808624 dnaK Mycobacterium bovis BCG str. Mexico putative chaperone protein YP_005169830.1 421096 D 717522 CDS YP_005169831.1 378770098 11808625 422970..423677 1 NC_016804.1 Differs from Rv0351 by 1aa, L224S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; protein grpE 423677 grpE 11808625 grpE Mycobacterium bovis BCG str. Mexico protein grpE YP_005169831.1 422970 D 717522 CDS YP_005169832.1 378770099 11808626 423713..424900 1 NC_016804.1 Differs from Rv0352 and Mb0360 by 1aa, A280T in BCG Pasteur, BCG Tokyo and BCG Mexico; chaperone protein DnaJ 424900 dnaJ1 11808626 dnaJ1 Mycobacterium bovis BCG str. Mexico chaperone protein DnaJ YP_005169832.1 423713 D 717522 CDS YP_005169833.1 378770100 11808627 424900..425280 1 NC_016804.1 putative heat shock protein transcriptional regulator 425280 hspR 11808627 hspR Mycobacterium bovis BCG str. Mexico putative heat shock protein transcriptional regulator YP_005169833.1 424900 D 717522 CDS YP_005169834.1 378770101 11808628 complement(425303..435826) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE7 and PPE8 exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 2 bp insertion (*-TA) resulting in the absence of a stop codon between the 2 genes, leads to a single product, and an altered C-terminus; PPE family protein 435826 PPE8 11808628 PPE8 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169834.1 425303 R 717522 CDS YP_005169835.1 378770102 11808629 complement(435977..436621) 1 NC_016804.1 hypothetical protein 436621 11808629 BCGMEX_0364c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169835.1 435977 R 717522 CDS YP_005169836.1 378770103 11808630 complement(436618..437916) 1 NC_016804.1 adenylosuccinate synthetase 437916 purA 11808630 purA Mycobacterium bovis BCG str. Mexico adenylosuccinate synthetase YP_005169836.1 436618 R 717522 CDS YP_005169837.1 378770104 11808631 438007..438654 1 NC_016804.1 hypothetical protein 438654 11808631 BCGMEX_0366 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169837.1 438007 D 717522 CDS YP_005169838.1 378770105 11808632 438665..439444 1 NC_016804.1 Differs from Rv0359 by 1aa, T252A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 439444 11808632 BCGMEX_0367 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005169838.1 438665 D 717522 CDS YP_005169839.1 378770106 11808633 complement(439449..439886) 1 NC_016804.1 hypothetical protein 439886 11808633 BCGMEX_0368c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169839.1 439449 R 717522 CDS YP_005169840.1 378770107 11808634 439969..440796 1 NC_016804.1 hypothetical protein 440796 11808634 BCGMEX_0369 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169840.1 439969 D 717522 CDS YP_005169841.1 378770108 11808635 441018..442400 1 NC_016804.1 Differs from Mb0362 by 1aa, V292A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative Mg2+ transport transmembrane protein 442400 mgtE 11808635 mgtE Mycobacterium bovis BCG str. Mexico putative Mg2+ transport transmembrane protein YP_005169841.1 441018 D 717522 CDS YP_005169842.1 378770109 11808636 complement(442412..443446) 1 NC_016804.1 Fructose-bisphosphate aldolase 443446 fba 11808636 fba Mycobacterium bovis BCG str. Mexico Fructose-bisphosphate aldolase YP_005169842.1 442412 R 717522 CDS YP_005169843.1 378770110 11808637 443542..444225 1 NC_016804.1 Differs from Rv0364 by 1aa, L193I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 444225 11808637 BCGMEX_0372 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169843.1 443542 D 717522 CDS YP_005169844.1 378770111 11808638 complement(444214..445344) 1 NC_016804.1 hypothetical protein 445344 11808638 BCGMEX_0373c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169844.1 444214 R 717522 CDS YP_005169845.1 378770112 11808639 complement(445369..445962) 1 NC_016804.1 hypothetical protein 445962 11808639 BCGMEX_0374c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169845.1 445369 R 717522 CDS YP_005169846.1 378770113 11808640 complement(445991..446380) 1 NC_016804.1 hypothetical protein 446380 11808640 BCGMEX_0375c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169846.1 445991 R 717522 CDS YP_005169847.1 378770114 11808641 complement(446461..447672) 1 NC_016804.1 Differs from Rv0368c by 1aa, H249R, and from Mb0375c by 1aa, G371S in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 447672 11808641 BCGMEX_0376c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169847.1 446461 R 717522 CDS YP_005169848.1 378770115 11808642 complement(447678..448193) 1 NC_016804.1 putative membrane oxidoreductase 448193 11808642 BCGMEX_0377c Mycobacterium bovis BCG str. Mexico putative membrane oxidoreductase YP_005169848.1 447678 R 717522 CDS YP_005169849.1 378770116 11808643 complement(448294..449190) 1 NC_016804.1 Differs from Rv0370c by 1aa, E201G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 449190 11808643 BCGMEX_0378c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005169849.1 448294 R 717522 CDS YP_005169850.1 378770117 11808644 complement(449187..449780) 1 NC_016804.1 hypothetical protein 449780 11808644 BCGMEX_0379c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169850.1 449187 R 717522 CDS YP_005169851.1 378770118 11808645 complement(449777..450532) 1 NC_016804.1 Differs from Mb0379c by 1aa, G161S in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 450532 11808645 BCGMEX_0380c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169851.1 449777 R 717522 CDS YP_005169852.1 378770119 11808646 complement(450551..452950) 1 NC_016804.1 Differs from Rv0373c by 1aa, S122F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative carbon monoxide dehydrogenase large chain 452950 11808646 BCGMEX_0381c Mycobacterium bovis BCG str. Mexico putative carbon monoxide dehydrogenase large chain YP_005169852.1 450551 R 717522 CDS YP_005169853.1 378770120 11808647 complement(452947..453426) 1 NC_016804.1 putative carbon monoxide dehydrogenase small chain 453426 11808647 BCGMEX_0382c Mycobacterium bovis BCG str. Mexico putative carbon monoxide dehydrogenase small chain YP_005169853.1 452947 R 717522 CDS YP_005169854.1 378770121 11808648 complement(453441..454301) 1 NC_016804.1 putative carbon monoxide dehydrogenase medium chain 454301 11808648 BCGMEX_0383c Mycobacterium bovis BCG str. Mexico putative carbon monoxide dehydrogenase medium chain YP_005169854.1 453441 R 717522 CDS YP_005169855.1 378770122 11808649 complement(454377..455519) 1 NC_016804.1 hypothetical protein 455519 11808649 BCGMEX_0384c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169855.1 454377 R 717522 CDS YP_005169856.1 378770123 11808650 455568..456533 1 NC_016804.1 Differs from Rv0377 by 1aa, R302P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 456533 11808650 BCGMEX_0385 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005169856.1 455568 D 717522 CDS YP_005169857.1 378770124 11808651 456784..457005 1 NC_016804.1 putative glycine rich protein 457005 11808651 BCGMEX_0386 Mycobacterium bovis BCG str. Mexico putative glycine rich protein YP_005169857.1 456784 D 717522 CDS YP_005169858.1 378770125 11808652 457124..457339 1 NC_016804.1 putative protein transport protein 457339 secE2 11808652 secE2 Mycobacterium bovis BCG str. Mexico putative protein transport protein YP_005169858.1 457124 D 717522 CDS YP_005169859.1 378770126 11808653 complement(457415..457966) 1 NC_016804.1 putative RNA methyltransferase 457966 11808653 BCGMEX_0388c Mycobacterium bovis BCG str. Mexico putative RNA methyltransferase YP_005169859.1 457415 R 717522 CDS YP_005169860.1 378770127 11808654 complement(458062..458970) 1 NC_016804.1 hypothetical protein 458970 11808654 BCGMEX_0389c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169860.1 458062 R 717522 CDS YP_005169861.1 378770128 11808655 complement(458988..459527) 1 NC_016804.1 orotate phosphoribosyltransferase 459527 pyrE 11808655 pyrE Mycobacterium bovis BCG str. Mexico orotate phosphoribosyltransferase YP_005169861.1 458988 R 717522 CDS YP_005169862.1 378770129 11808656 complement(459608..460462) 1 NC_016804.1 putative secreted protein 460462 11808656 BCGMEX_0391c Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005169862.1 459608 R 717522 CDS YP_005169863.1 378770130 11808657 complement(460603..463149) 1 NC_016804.1 chaperone protein clpB 463149 clpB 11808657 clpB Mycobacterium bovis BCG str. Mexico chaperone protein clpB YP_005169863.1 460603 R 717522 CDS YP_005169864.1 378770131 11808658 463282..464454 1 NC_016804.1 putative monooxygenase 464454 11808658 BCGMEX_0393 Mycobacterium bovis BCG str. Mexico putative monooxygenase YP_005169864.1 463282 D 717522 CDS YP_005169865.1 378770132 11808659 464558..467815 1 NC_016804.1 Differs from Mb0393 by 1aa, D902A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, LuxR family 467815 11808659 BCGMEX_0394 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, LuxR family YP_005169865.1 464558 D 717522 CDS YP_005169866.1 378770133 11808660 complement(467819..469150) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0388c and Rv0387c exist as 2 separate genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, 3 different base substitutions, the first of 14 bases, the second of 8 bases, and lastly of 28 bases, leads to a longer single product. Differs from Mb0394c by 1aa, T361A in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 469150 PPE9 11808660 PPE9 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169866.1 467819 R 717522 CDS YP_005169867.1 378770134 11808661 469484..470743 1 NC_016804.1 Differs from Rv0389 by 2aa, G8E, T332I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phosphoribosylglycinamide formyltransferase 2 470743 purT 11808661 purT Mycobacterium bovis BCG str. Mexico phosphoribosylglycinamide formyltransferase 2 YP_005169867.1 469484 D 717522 CDS YP_005169868.1 378770135 11808662 470740..471162 1 NC_016804.1 hypothetical protein 471162 11808662 BCGMEX_0397 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169868.1 470740 D 717522 CDS YP_005169869.1 378770136 11808663 471159..472379 1 NC_016804.1 O-succinylhomoserine sulfhydrylase 472379 metZ 11808663 metZ Mycobacterium bovis BCG str. Mexico O-succinylhomoserine sulfhydrylase YP_005169869.1 471159 D 717522 CDS YP_005169870.1 378770137 11808664 complement(472376..473788) 1 NC_016804.1 Differs from Rv0392c by 1aa, A241V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative membrane NADH dehydrogenase 473788 ndhA 11808664 ndhA Mycobacterium bovis BCG str. Mexico putative membrane NADH dehydrogenase YP_005169870.1 472376 R 717522 CDS YP_005169871.1 378770138 11808665 473930..475255 1 NC_016804.1 hypothetical protein 475255 11808665 BCGMEX_0400 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169871.1 473930 D 717522 CDS YP_005169872.1 378770139 11808666 complement(475271..475990) 1 NC_016804.1 putative secreted protein 475990 11808666 BCGMEX_0401c Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005169872.1 475271 R 717522 CDS YP_005169873.1 378770140 11808667 476089..476493 1 NC_016804.1 Differs from Rv0395 by 1aa, A80V in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 476493 11808667 BCGMEX_0402 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169873.1 476089 D 717522 CDS YP_005169874.1 378770141 11808668 476499..476891 1 NC_016804.1 hypothetical protein 476891 11808668 BCGMEX_0403 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169874.1 476499 D 717522 CDS YP_005169875.1 378770142 11808669 476965..477333 1 NC_016804.1 hypothetical protein 477333 11808669 BCGMEX_0404 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169875.1 476965 D 717522 CDS YP_005169876.1 378770143 11808670 477543..477791 1 NC_016804.1 hypothetical protein 477791 11808670 BCGMEX_0405 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169876.1 477543 D 717522 CDS YP_005169877.1 378770144 11808671 complement(477828..478469) 1 NC_016804.1 hypothetical protein 478469 11808671 BCGMEX_0406c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169877.1 477828 R 717522 CDS YP_005169878.1 378770145 11808672 complement(478476..479705) 1 NC_016804.1 putative lipoprotein 479705 lpqK 11808672 lpqK Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005169878.1 478476 R 717522 CDS YP_005169879.1 378770146 11808673 complement(479715..480902) 1 NC_016804.1 putative acyl-CoA dehydrogenase 480902 fadE7 11808673 fadE7 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005169879.1 479715 R 717522 CDS YP_005169880.1 378770147 11808674 480938..481309 1 NC_016804.1 transmembrane protein 481309 11808674 BCGMEX_0409 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169880.1 480938 D 717522 CDS YP_005169881.1 378770148 11808675 complement(481504..482607) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, mmpL1 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion splits mmpL1 into 2 parts, mmpL1a and mmpL1b; putative transmembrane transport protein 482607 mmpL1b 11808675 mmpL1b Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005169881.1 481504 R 717522 CDS YP_005169882.1 378770149 11808676 complement(482604..484379) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, mmpL1 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base deletion splits mmpL1 into 2 parts, mmpL1a and mmpL1b. Differs from Rv0402c by 1aa, P451L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane transport protein 484379 mmpL1a 11808676 mmpL1a Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005169882.1 482604 R 717522 CDS YP_005169883.1 378770150 11808677 complement(484376..484804) 1 NC_016804.1 hypothetical protein 484804 mmpS1 11808677 mmpS1 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169883.1 484376 R 717522 CDS YP_005169884.1 378770151 11808678 485125..486882 1 NC_016804.1 Differs from Mb0411 by 1aa, S300S, and from Rv0404 by 2aa, A88T, S300A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative fatty-acid-CoA ligase 486882 fadD30 11808678 fadD30 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005169884.1 485125 D 717522 CDS YP_005169885.1 378770152 11808679 486879..488261 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, pks6 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to single base insertion splits pks6 into 2 parts,pks6a and pks6b; putative membrane bound polyketide synthase 488261 pks6a 11808679 pks6a Mycobacterium bovis BCG str. Mexico putative membrane bound polyketide synthase YP_005169885.1 486879 D 717522 CDS YP_005169886.1 378770153 11808680 488248..491088 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, pks6 exists as a single gene. In Mycobacterium bovis, a frameshift due to single base insertion, splits pks6 into 2 parts, pks6a and pks6b. Differs from Mb0413 by 1aa, M921V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative membrane bound polyketide synthase 491088 pks6b 11808680 pks6b Mycobacterium bovis BCG str. Mexico putative membrane bound polyketide synthase YP_005169886.1 488248 D 717522 CDS YP_005169887.1 378770154 11808681 complement(491036..491854) 1 NC_016804.1 beta lactamase like protein 491854 11808681 BCGMEX_0416c Mycobacterium bovis BCG str. Mexico beta lactamase like protein YP_005169887.1 491036 R 717522 CDS YP_005169888.1 378770155 11808682 491932..492942 1 NC_016804.1 F420-dependent glucose-6-phosphate dehydrogenase 492942 fgd1 11808682 fgd1 Mycobacterium bovis BCG str. Mexico F420-dependent glucose-6-phosphate dehydrogenase YP_005169888.1 491932 D 717522 CDS YP_005169889.1 378770156 11808683 492935..495007 1 NC_016804.1 Differs from Rv0408 by 1aa, A102G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phosphate acetyltransferase 495007 pta 11808683 pta Mycobacterium bovis BCG str. Mexico phosphate acetyltransferase YP_005169889.1 492935 D 717522 CDS YP_005169890.1 378770157 11808684 495000..496157 1 NC_016804.1 acetate kinase 496157 ackA 11808684 ackA Mycobacterium bovis BCG str. Mexico acetate kinase YP_005169890.1 495000 D 717522 CDS YP_005169891.1 378770158 11808685 complement(496211..498463) 1 NC_016804.1 Serine/threonine protein kinase 498463 pknG 11808685 pknG Mycobacterium bovis BCG str. Mexico Serine/threonine protein kinase YP_005169891.1 496211 R 717522 CDS YP_005169892.1 378770159 11808686 complement(498463..499449) 1 NC_016804.1 putative glutamine-binding lipoprotein 499449 glnH 11808686 glnH Mycobacterium bovis BCG str. Mexico putative glutamine-binding lipoprotein YP_005169892.1 498463 R 717522 CDS YP_005169893.1 378770160 11808687 complement(499449..500768) 1 NC_016804.1 Differs from Rv0412c by 1aa, Y355D in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 500768 11808687 BCGMEX_0422c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169893.1 499449 R 717522 CDS YP_005169894.1 378770161 11808688 500862..501515 1 NC_016804.1 putative mutator mutT3 protein 501515 mutT3 11808688 mutT3 Mycobacterium bovis BCG str. Mexico putative mutator mutT3 protein YP_005169894.1 500862 D 717522 CDS YP_005169895.1 378770162 11808689 complement(501499..502167) 1 NC_016804.1 Thiamin-phosphate pyrophosphorylase 502167 thiE 11808689 thiE Mycobacterium bovis BCG str. Mexico Thiamin-phosphate pyrophosphorylase YP_005169895.1 501499 R 717522 CDS YP_005169896.1 378770163 11808690 502297..503319 1 NC_016804.1 Differs from Mb0423 by 1aa, A158V in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Thiamine biosynthesis oxidoreductase 503319 thiO 11808690 thiO Mycobacterium bovis BCG str. Mexico Thiamine biosynthesis oxidoreductase YP_005169896.1 502297 D 717522 CDS YP_005169897.1 378770164 11808691 503316..503522 1 NC_016804.1 Sulfur carrier protein 503522 thiS 11808691 thiS Mycobacterium bovis BCG str. Mexico Sulfur carrier protein YP_005169897.1 503316 D 717522 CDS YP_005169898.1 378770165 11808692 503515..504273 1 NC_016804.1 Differs from Rv0417 by 1aa, C75S in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; thiazole synthase 504273 thiG 11808692 thiG Mycobacterium bovis BCG str. Mexico thiazole synthase YP_005169898.1 503515 D 717522 CDS YP_005169899.1 378770166 11808693 504645..506147 1 NC_016804.1 putative lipoprotein aminopeptidase 506147 lpqL 11808693 lpqL Mycobacterium bovis BCG str. Mexico putative lipoprotein aminopeptidase YP_005169899.1 504645 D 717522 CDS YP_005169900.1 378770167 11808694 506235..507731 1 NC_016804.1 Differs from Rv0419 by 2aa, T73A, T297A, and from Mb0427 by 1aa, T73A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein peptidase 507731 lpqM 11808694 lpqM Mycobacterium bovis BCG str. Mexico putative lipoprotein peptidase YP_005169900.1 506235 D 717522 CDS YP_005169901.1 378770168 11808695 complement(507710..508120) 1 NC_016804.1 Differs from Mb0428c by 1aa, G21E in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 508120 11808695 BCGMEX_0430c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169901.1 507710 R 717522 CDS YP_005169902.1 378770169 11808696 complement(508281..508910) 1 NC_016804.1 hypothetical protein 508910 11808696 BCGMEX_0431c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169902.1 508281 R 717522 CDS YP_005169903.1 378770170 11808697 complement(508907..509704) 1 NC_016804.1 phosphomethylpyrimidine kinase 509704 thiD 11808697 thiD Mycobacterium bovis BCG str. Mexico phosphomethylpyrimidine kinase YP_005169903.1 508907 R 717522 CDS YP_005169904.1 378770171 11808698 complement(509731..511374) 1 NC_016804.1 Thiamin biosynthesis protein 511374 thiC 11808698 thiC Mycobacterium bovis BCG str. Mexico Thiamin biosynthesis protein YP_005169904.1 509731 R 717522 CDS YP_005169905.1 378770172 11808699 complement(511526..511801) 1 NC_016804.1 hypothetical protein 511801 11808699 BCGMEX_0434c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169905.1 511526 R 717522 CDS YP_005169906.1 378770173 11808700 complement(511851..516470) 1 NC_016804.1 Differs from Rv0425c by 1aa, A222E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative metal cation transporting P-type ATPase 516470 ctpH 11808700 ctpH Mycobacterium bovis BCG str. Mexico putative metal cation transporting P-type ATPase YP_005169906.1 511851 R 717522 CDS YP_005169907.1 378770174 11808701 complement(516522..516965) 1 NC_016804.1 putative transmembrane protein 516965 11808701 BCGMEX_0436c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169907.1 516522 R 717522 CDS YP_005169908.1 378770175 11808702 complement(517166..518041) 1 NC_016804.1 Exodeoxyribonuclease III protein 518041 xthA 11808702 xthA Mycobacterium bovis BCG str. Mexico Exodeoxyribonuclease III protein YP_005169908.1 517166 R 717522 CDS YP_005169909.1 378770176 11808703 complement(518044..518952) 1 NC_016804.1 Differs from Rv0428c by 1aa G149D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 518952 11808703 BCGMEX_0438c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169909.1 518044 R 717522 CDS YP_005169910.1 378770177 11808704 complement(518952..519545) 1 NC_016804.1 Differs from Mb0437c by 1aa, A2T in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; peptide deformylase 519545 def 11808704 def Mycobacterium bovis BCG str. Mexico peptide deformylase YP_005169910.1 518952 R 717522 CDS YP_005169911.1 378770178 11808705 519882..520190 1 NC_016804.1 hypothetical protein 520190 11808705 BCGMEX_0440 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169911.1 519882 D 717522 CDS YP_005169912.1 378770179 11808706 520222..520716 1 NC_016804.1 Differs from Rv0431 by 2aa, G38V, A87T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative tuberculin related peptide 520716 11808706 BCGMEX_0441 Mycobacterium bovis BCG str. Mexico putative tuberculin related peptide YP_005169912.1 520222 D 717522 CDS YP_005169913.1 378770180 11808707 520749..521471 1 NC_016804.1 Superoxide dismutase (Cu-Zn) 521471 sodC 11808707 sodC Mycobacterium bovis BCG str. Mexico Superoxide dismutase (Cu-Zn) YP_005169913.1 520749 D 717522 CDS YP_005169914.1 378770181 11808708 521473..522603 1 NC_016804.1 carboxylate-amine ligase 522603 11808708 BCGMEX_0443 Mycobacterium bovis BCG str. Mexico carboxylate-amine ligase YP_005169914.1 521473 D 717522 CDS YP_005169915.1 378770182 11808709 522660..523316 1 NC_016804.1 Differs from Rv0434 by 1aa, A190T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 523316 11808709 BCGMEX_0444 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169915.1 522660 D 717522 CDS YP_005169916.1 378770183 11808710 complement(523496..525682) 1 NC_016804.1 putative ATPase 525682 11808710 BCGMEX_0445c Mycobacterium bovis BCG str. Mexico putative ATPase YP_005169916.1 523496 R 717522 CDS YP_005169917.1 378770184 11808711 complement(525679..526539) 1 NC_016804.1 Differs from Rv0436c by 1aa, V167G in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative CDP-diacylglycerol--serine O-phosphatidyltransferase 526539 pssA 11808711 pssA Mycobacterium bovis BCG str. Mexico putative CDP-diacylglycerol--serine O-phosphatidyltransferase YP_005169917.1 525679 R 717522 CDS YP_005169918.1 378770185 11808712 complement(526536..527231) 1 NC_016804.1 phosphatidylserine decarboxylase 527231 psd 11808712 psd Mycobacterium bovis BCG str. Mexico phosphatidylserine decarboxylase YP_005169918.1 526536 R 717522 CDS YP_005169919.1 378770186 11808713 complement(527292..528509) 1 NC_016804.1 Differs from Rv0438c by 1aa, I15M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative molybdopterin biosynthesis protein 528509 moeA2 11808713 moeA2 Mycobacterium bovis BCG str. Mexico putative molybdopterin biosynthesis protein YP_005169919.1 527292 R 717522 CDS YP_005169920.1 378770187 11808714 complement(528528..529463) 1 NC_016804.1 putative dehydrogenase/reductase 529463 11808714 BCGMEX_0449c Mycobacterium bovis BCG str. Mexico putative dehydrogenase/reductase YP_005169920.1 528528 R 717522 CDS YP_005169921.1 378770188 11808715 529757..531379 1 NC_016804.1 60 kDa chaperonin 1 531379 groEL 11808715 groEL Mycobacterium bovis BCG str. Mexico 60 kDa chaperonin 1 YP_005169921.1 529757 D 717522 CDS YP_005169922.1 378770189 11808716 complement(531445..531873) 1 NC_016804.1 hypothetical protein 531873 11808716 BCGMEX_0451c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169922.1 531445 R 717522 CDS YP_005169923.1 378770190 11808717 complement(531900..533339) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transition creates an in-frame stop at codon 8, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (479 aa versus 487 aa). Differs from Mb0450c by 1aa, T214K, and from Rv0442c by 2aa, E23K, T214K in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 533339 PPE10 11808717 PPE10 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169923.1 531900 R 717522 CDS YP_005169924.1 378770191 11808718 533545..534060 1 NC_016804.1 hypothetical protein 534060 11808718 BCGMEX_0453 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169924.1 533545 D 717522 CDS YP_005169925.1 378770192 11808719 complement(534240..534938) 1 NC_016804.1 Differs from Rv0444c by 2aa, D107G, E184G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; disfunctional anti-sigma-K factor 534938 rskA 11808719 rskA Mycobacterium bovis BCG str. Mexico disfunctional anti-sigma-K factor YP_005169925.1 534240 R 717522 CDS YP_005169926.1 378770193 11808720 complement(534982..535545) 1 NC_016804.1 Differs from Rv0445c and Mb0453c by 1aa, I1M, due to c-t transition at position Equivalent to Mycobacterium tuberculosis strain H37Rv, 534394. Expression may be affected in Mycobacterium bovis BCG Pasteur and BCG Mexico (late strains).; RNA polymerase sigma factor 535545 sigK 11808720 sigK Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005169926.1 534982 R 717522 CDS YP_005169927.1 378770194 11808721 complement(535594..536364) 1 NC_016804.1 transmembrane protein 536364 11808721 BCGMEX_0456c Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169927.1 535594 R 717522 CDS YP_005169928.1 378770195 11808722 complement(536373..537656) 1 NC_016804.1 putative cyclopropane-fatty-acyl-phospholipid synthase 537656 ufaA1 11808722 ufaA1 Mycobacterium bovis BCG str. Mexico putative cyclopropane-fatty-acyl-phospholipid synthase YP_005169928.1 536373 R 717522 CDS YP_005169929.1 378770196 11808723 complement(537653..538318) 1 NC_016804.1 hypothetical protein 538318 11808723 BCGMEX_0458c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169929.1 537653 R 717522 CDS YP_005169930.1 378770197 11808724 complement(538378..539697) 1 NC_016804.1 hypothetical protein 539697 11808724 BCGMEX_0459c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169930.1 538378 R 717522 CDS YP_005169931.1 378770198 11808725 complement(539737..542640) 1 NC_016804.1 Differs from Mb0458c by 1aa, A314T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane transport protein 542640 mmpL4 11808725 mmpL4 Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005169931.1 539737 R 717522 CDS YP_005169932.1 378770199 11808726 complement(542637..543059) 1 NC_016804.1 hypothetical protein 543059 mmpS4 11808726 mmpS4 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169932.1 542637 R 717522 CDS YP_005169933.1 378770200 11808727 543291..544001 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 544001 11808727 BCGMEX_0462 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005169933.1 543291 D 717522 CDS YP_005169934.1 378770201 11808728 544323..545879 1 NC_016804.1 PPE family protein 545879 PPE11 11808728 PPE11 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005169934.1 544323 D 717522 CDS YP_005169935.1 378770202 11808729 545984..546334 1 NC_016804.1 hypothetical protein 546334 11808729 BCGMEX_0464 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169935.1 545984 D 717522 CDS YP_005169936.1 378770203 11808730 complement(546524..546970) 1 NC_016804.1 hypothetical protein 546970 11808730 BCGMEX_0465c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169936.1 546524 R 717522 CDS YP_005169937.1 378770204 11808731 complement(547038..547952) 1 NC_016804.1 Enoyl-CoA hydratase 547952 echA2 11808731 echA2 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005169937.1 547038 R 717522 CDS YP_005169938.1 378770205 11808732 complement(548225..548506) 1 NC_016804.1 hypothetical protein 548506 11808732 BCGMEX_0467c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169938.1 548225 R 717522 CDS YP_005169939.1 378770206 11808733 complement(548735..550765) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a possible RBS upstream leads to an earlier start resulting in a slightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (676 aa versus 673 aa); putative peptidase 550765 11808733 BCGMEX_0468c Mycobacterium bovis BCG str. Mexico putative peptidase YP_005169939.1 548735 R 717522 CDS YP_005169940.1 378770207 11808734 550824..552347 1 NC_016804.1 putative aldehyde dehydrogenase 552347 11808734 BCGMEX_0469 Mycobacterium bovis BCG str. Mexico putative aldehyde dehydrogenase YP_005169940.1 550824 D 717522 CDS YP_005169941.1 378770208 11808735 552347..552838 1 NC_016804.1 hypothetical protein 552838 11808735 BCGMEX_0470 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169941.1 552347 D 717522 CDS YP_005169942.1 378770209 11808736 552898..553137 1 NC_016804.1 hypothetical protein 553137 11808736 BCGMEX_0471 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169942.1 552898 D 717522 CDS YP_005169943.1 378770210 11808737 553175..553699 1 NC_016804.1 putative transmembrane protein 553699 11808737 BCGMEX_0472 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169943.1 553175 D 717522 CDS YP_005169944.1 378770211 11808738 553763..555157 1 NC_016804.1 dihydrolipoamide dehydrogenase 555157 lpd 11808738 lpd Mycobacterium bovis BCG str. Mexico dihydrolipoamide dehydrogenase YP_005169944.1 553763 D 717522 CDS YP_005169945.1 378770212 11808739 555165..555458 1 NC_016804.1 hypothetical protein 555458 11808739 BCGMEX_0474 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169945.1 555165 D 717522 CDS YP_005169946.1 378770213 11808740 complement(555462..556034) 1 NC_016804.1 hypothetical protein 556034 11808740 BCGMEX_0475c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169946.1 555462 R 717522 CDS YP_005169947.1 378770214 11808741 complement(556031..557455) 1 NC_016804.1 Differs from Rv0465c by 2aa, D36N, R106C, and from Mb0474c by 1aa, R326Q in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 557455 11808741 BCGMEX_0476c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005169947.1 556031 R 717522 CDS YP_005169948.1 378770215 11808742 557607..558401 1 NC_016804.1 hypothetical protein 558401 11808742 BCGMEX_0477 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169948.1 557607 D 717522 CDS YP_005169949.1 378770216 11808743 558676..559962 1 NC_016804.1 isocitrate lyase 559962 icl 11808743 icl Mycobacterium bovis BCG str. Mexico isocitrate lyase YP_005169949.1 558676 D 717522 CDS YP_005169950.1 378770217 11808744 560044..560904 1 NC_016804.1 3-hydroxybutyryl-CoA dehydrogenase 560904 fadB2 11808744 fadB2 Mycobacterium bovis BCG str. Mexico 3-hydroxybutyryl-CoA dehydrogenase YP_005169950.1 560044 D 717522 CDS YP_005169951.1 378770218 11808745 561037..561897 1 NC_016804.1 putative mycolic acid synthase 561897 umaA1 11808745 umaA1 Mycobacterium bovis BCG str. Mexico putative mycolic acid synthase YP_005169951.1 561037 D 717522 CDS YP_005169952.1 378770219 11808746 complement(561997..562860) 1 NC_016804.1 Mycolic acid synthase 562860 pcaA 11808746 pcaA Mycobacterium bovis BCG str. Mexico Mycolic acid synthase YP_005169952.1 561997 R 717522 CDS YP_005169953.1 378770220 11808747 complement(563003..563443) 1 NC_016804.1 hypothetical protein 563443 11808747 BCGMEX_0482c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169953.1 563003 R 717522 CDS YP_005169954.1 378770221 11808748 complement(563374..563862) 1 NC_016804.1 hypothetical protein 563862 11808748 BCGMEX_0483c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169954.1 563374 R 717522 CDS YP_005169955.1 378770222 11808749 complement(563872..564576) 1 NC_016804.1 Differs from Rv0472c and Mb0482c by 1aa, D162G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, TetR family 564576 11808749 BCGMEX_0484c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005169955.1 563872 R 717522 CDS YP_005169956.1 378770223 11808750 564716..566083 1 NC_016804.1 Differs from Rv0473 by 1aa, R5K in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; transmembrane protein 566083 11808750 BCGMEX_0485 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005169956.1 564716 D 717522 CDS YP_005169957.1 378770224 11808751 566170..566592 1 NC_016804.1 putative transcriptional regulatory protein 566592 11808751 BCGMEX_0486 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005169957.1 566170 D 717522 CDS YP_005169958.1 378770225 11808752 566946..567545 1 NC_016804.1 heparin-binding hemagglutinin 567545 hbhA 11808752 hbhA Mycobacterium bovis BCG str. Mexico heparin-binding hemagglutinin YP_005169958.1 566946 D 717522 CDS YP_005169959.1 378770226 11808753 567657..567920 1 NC_016804.1 putative transmembrane protein 567920 11808753 BCGMEX_0488 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169959.1 567657 D 717522 CDS YP_005169960.1 378770227 11808754 567925..568371 1 NC_016804.1 putative secreted protein 568371 11808754 BCGMEX_0489 Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005169960.1 567925 D 717522 CDS YP_005169961.1 378770228 11808755 568371..569045 1 NC_016804.1 Deoxyribose-phosphate aldolase 569045 deoC 11808755 deoC Mycobacterium bovis BCG str. Mexico Deoxyribose-phosphate aldolase YP_005169961.1 568371 D 717522 CDS YP_005169962.1 378770229 11808756 complement(569070..570116) 1 NC_016804.1 hypothetical protein 570116 11808756 BCGMEX_0491c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169962.1 569070 R 717522 CDS YP_005169963.1 378770230 11808757 complement(570113..571048) 1 NC_016804.1 In Mycobacterium bovis, a 56 bp deletion results in a different NH2 part and leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (311 aa versus 340 aa); hypothetical protein 571048 11808757 BCGMEX_0492c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169963.1 570113 R 717522 CDS YP_005169964.1 378770231 11808758 complement(571081..571605) 1 NC_016804.1 hypothetical protein 571605 11808758 BCGMEX_0493c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169964.1 571081 R 717522 CDS YP_005169965.1 378770232 11808759 571632..572741 1 NC_016804.1 UDP-N-acetylenolpyruvoylglucosamine reductase 572741 murB 11808759 murB Mycobacterium bovis BCG str. Mexico UDP-N-acetylenolpyruvoylglucosamine reductase YP_005169965.1 571632 D 717522 CDS YP_005169966.1 378770233 11808760 572803..574158 1 NC_016804.1 putative lipoprotein 574158 lprQ 11808760 lprQ Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005169966.1 572803 D 717522 CDS YP_005169967.1 378770234 11808761 complement(574139..574894) 1 NC_016804.1 Differs from Rv0484c by 1aa, L140I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Short chain type oxidoreductase 574894 11808761 BCGMEX_0496c Mycobacterium bovis BCG str. Mexico Short chain type oxidoreductase YP_005169967.1 574139 R 717522 CDS YP_005169968.1 378770235 11808762 575077..576393 1 NC_016804.1 putative transcriptional regulatory protein 576393 11808762 BCGMEX_0497 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005169968.1 575077 D 717522 CDS YP_005169969.1 378770236 11808763 576441..577883 1 NC_016804.1 putative glycosyltransferase 577883 11808763 BCGMEX_0498 Mycobacterium bovis BCG str. Mexico putative glycosyltransferase YP_005169969.1 576441 D 717522 CDS YP_005169970.1 378770237 11808764 577880..578431 1 NC_016804.1 hypothetical protein 578431 11808764 BCGMEX_0499 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169970.1 577880 D 717522 CDS YP_005169971.1 378770238 11808765 578873..579478 1 NC_016804.1 putative amino-acid transporter 579478 11808765 BCGMEX_0500 Mycobacterium bovis BCG str. Mexico putative amino-acid transporter YP_005169971.1 578873 D 717522 CDS YP_005169972.1 378770239 11808766 579635..580384 1 NC_016804.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 580384 gpmA 11808766 gpmA Mycobacterium bovis BCG str. Mexico 2,3-bisphosphoglycerate-independent phosphoglycerate mutase YP_005169972.1 579635 D 717522 CDS YP_005169973.1 378770240 11808767 580558..581790 1 NC_016804.1 Differs from Rv0490 and Mb0500 by 1aa, S109F in BCG Pasteur, BCG Tokio and BCG Mexico; Sensor-like histidine kinase 581790 senX3 11808767 senX3 Mycobacterium bovis BCG str. Mexico Sensor-like histidine kinase YP_005169973.1 580558 D 717522 CDS YP_005169974.1 378770241 11808768 581941..582624 1 NC_016804.1 Differs from Rv0491 and Mb0501 by 1aa, T18A in BCG Pasteur and BCG Mexico, by 2aa, T18A, C219R in BCG Tokyo; Sensory transduction protein 582624 regX3 11808768 regX3 Mycobacterium bovis BCG str. Mexico Sensory transduction protein YP_005169974.1 581941 D 717522 CDS YP_005169975.1 378770242 11808769 complement(582621..584510) 1 NC_016804.1 Differs from Rv0492c by 1aa, F520L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase GMC-type 584510 11808769 BCGMEX_0504c Mycobacterium bovis BCG str. Mexico putative oxidoreductase GMC-type YP_005169975.1 582621 R 717522 CDS YP_005169976.1 378770243 11808770 complement(584507..584836) 1 NC_016804.1 hypothetical protein 584836 11808770 BCGMEX_0505c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169976.1 584507 R 717522 CDS YP_005169977.1 378770244 11808771 complement(584833..585822) 1 NC_016804.1 Differs from Rv0493c by 1aa, G174S in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico. Also differs from Rv0493c by 1aa, S101G in BCG Mexico; hypothetical protein 585822 11808771 BCGMEX_0506c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169977.1 584833 R 717522 CDS YP_005169978.1 378770245 11808772 585827..586555 1 NC_016804.1 putative transcriptional regulatory protein, GntR family 586555 11808772 BCGMEX_0507 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, GntR family YP_005169978.1 585827 D 717522 CDS YP_005169979.1 378770246 11808773 complement(586556..587446) 1 NC_016804.1 hypothetical protein 587446 11808773 BCGMEX_0508c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169979.1 586556 R 717522 CDS YP_005169980.1 378770247 11808774 587478..588512 1 NC_016804.1 hypothetical protein 588512 11808774 BCGMEX_0509 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169980.1 587478 D 717522 CDS YP_005169981.1 378770248 11808775 588509..589441 1 NC_016804.1 putative transmembrane protein 589441 11808775 BCGMEX_0510 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169981.1 588509 D 717522 CDS YP_005169982.1 378770249 11808776 589457..590299 1 NC_016804.1 hypothetical protein 590299 11808776 BCGMEX_0511 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169982.1 589457 D 717522 CDS YP_005169983.1 378770250 11808777 590315..591190 1 NC_016804.1 hypothetical protein 591190 11808777 BCGMEX_0512 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169983.1 590315 D 717522 CDS YP_005169984.1 378770251 11808778 591215..592102 1 NC_016804.1 Differs from Rv0500 by 1aa, D227E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Pyrroline-5-carboxylate reductase 592102 proC 11808778 proC Mycobacterium bovis BCG str. Mexico Pyrroline-5-carboxylate reductase YP_005169984.1 591215 D 717522 CDS YP_005169985.1 378770252 11808779 592243..592479 1 NC_016804.1 hypothetical protein 592479 11808779 BCGMEX_0514 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169985.1 592243 D 717522 CDS YP_005169986.1 378770253 11808780 592786..593916 1 NC_016804.1 putative UDP-glucose 4-epimerase 593916 galE2 11808780 galE2 Mycobacterium bovis BCG str. Mexico putative UDP-glucose 4-epimerase YP_005169986.1 592786 D 717522 CDS YP_005169987.1 378770254 11808781 593923..594999 1 NC_016804.1 hypothetical protein 594999 11808781 BCGMEX_0516 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169987.1 593923 D 717522 CDS YP_005169988.1 378770255 11808782 complement(595003..595911) 1 NC_016804.1 cyclopropane-fatty-acyl-phospholipid synthase 2 595911 cmaA2 11808782 cmaA2 Mycobacterium bovis BCG str. Mexico cyclopropane-fatty-acyl-phospholipid synthase 2 YP_005169988.1 595003 R 717522 CDS YP_005169989.1 378770256 11808783 complement(595934..596434) 1 NC_016804.1 hypothetical protein 596434 11808783 BCGMEX_0518c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169989.1 595934 R 717522 CDS YP_005169990.1 378770257 11808784 complement(596596..597519) 1 NC_016804.1 putative phosphoserine phosphatase 597519 serB1 11808784 serB1 Mycobacterium bovis BCG str. Mexico putative phosphoserine phosphatase YP_005169990.1 596596 R 717522 CDS YP_005169991.1 378770258 11808785 597891..598334 1 NC_016804.1 hypothetical protein 598334 mmpS2 11808785 mmpS2 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169991.1 597891 D 717522 CDS YP_005169992.1 378770259 11808786 598331..601237 1 NC_016804.1 Differs from Mb0519 by 1aa, D119H, and from Rv0507 by 3aa, H426R, Y509D, C722S in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane transport protein 601237 mmpL2 11808786 mmpL2 Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005169992.1 598331 D 717522 CDS YP_005169993.1 378770260 11808787 601230..601523 1 NC_016804.1 hypothetical protein 601523 11808787 BCGMEX_0522 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005169993.1 601230 D 717522 CDS YP_005169994.1 378770261 11808788 601573..602979 1 NC_016804.1 glutamyl-tRNA reductase 602979 hemA 11808788 hemA Mycobacterium bovis BCG str. Mexico glutamyl-tRNA reductase YP_005169994.1 601573 D 717522 CDS YP_005169995.1 378770262 11808789 602989..603918 1 NC_016804.1 porphobilinogen deaminase 603918 hemC 11808789 hemC Mycobacterium bovis BCG str. Mexico porphobilinogen deaminase YP_005169995.1 602989 D 717522 CDS YP_005169996.1 378770263 11808790 603951..605648 1 NC_016804.1 Uroporphyrinogen-III methyltransferase 605648 hemD 11808790 hemD Mycobacterium bovis BCG str. Mexico Uroporphyrinogen-III methyltransferase YP_005169996.1 603951 D 717522 CDS YP_005169997.1 378770264 11808791 605734..606723 1 NC_016804.1 Differs from Rv0512 by 1aa, G246E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Delta-aminolevulinic acid dehydratase 606723 hemB 11808791 hemB Mycobacterium bovis BCG str. Mexico Delta-aminolevulinic acid dehydratase YP_005169997.1 605734 D 717522 CDS YP_005169998.1 378770265 11808792 606736..607284 1 NC_016804.1 putative transmembrane protein 607284 11808792 BCGMEX_0527 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169998.1 606736 D 717522 CDS YP_005169999.1 378770266 11808793 607281..607580 1 NC_016804.1 Differs from Mb0527 and Rv0514 by 1aa, G23A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 607580 11808793 BCGMEX_0528 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005169999.1 607281 D 717522 CDS YP_005170000.1 378770267 11808794 607683..609194 1 NC_016804.1 hypothetical protein 609194 11808794 BCGMEX_0529 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170000.1 607683 D 717522 CDS YP_005170001.1 378770268 11808795 complement(609191..609667) 1 NC_016804.1 hypothetical protein 609667 11808795 BCGMEX_0530c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170001.1 609191 R 717522 CDS YP_005170002.1 378770269 11808796 609878..611188 1 NC_016804.1 Differs from Rv0517 by 1aa, G394D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyltransferase 611188 11808796 BCGMEX_0531 Mycobacterium bovis BCG str. Mexico putative acyltransferase YP_005170002.1 609878 D 717522 CDS YP_005170003.1 378770270 11808797 611320..612015 1 NC_016804.1 hypothetical protein 612015 11808797 BCGMEX_0532 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170003.1 611320 D 717522 CDS YP_005170004.1 378770271 11808798 complement(612304..613206) 1 NC_016804.1 membrane protein 613206 11808798 BCGMEX_0533c Mycobacterium bovis BCG str. Mexico membrane protein YP_005170004.1 612304 R 717522 CDS YP_005170005.1 378770272 11808799 613387..613737 1 NC_016804.1 putative methyltransferase/methylase 613737 11808799 BCGMEX_0534 Mycobacterium bovis BCG str. Mexico putative methyltransferase/methylase YP_005170005.1 613387 D 717522 CDS YP_005170006.1 378770273 11808800 613730..614035 1 NC_016804.1 putative methyltransferase/methylase 614035 11808800 BCGMEX_0535 Mycobacterium bovis BCG str. Mexico putative methyltransferase/methylase YP_005170006.1 613730 D 717522 CDS YP_005170007.1 378770274 11808801 614170..615474 1 NC_016804.1 GabA permease 615474 gabP 11808801 gabP Mycobacterium bovis BCG str. Mexico GabA permease YP_005170007.1 614170 D 717522 CDS YP_005170008.1 378770275 11808802 complement(615458..615853) 1 NC_016804.1 hypothetical protein 615853 11808802 BCGMEX_0537c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170008.1 615458 R 717522 CDS YP_005170009.1 378770276 11808803 615967..617355 1 NC_016804.1 putative glutamate-1-semialdehyde aminotransferase 617355 hemL 11808803 hemL Mycobacterium bovis BCG str. Mexico putative glutamate-1-semialdehyde aminotransferase YP_005170009.1 615967 D 717522 CDS YP_005170010.1 378770277 11808804 617355..617963 1 NC_016804.1 hypothetical protein 617963 11808804 BCGMEX_0539 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170010.1 617355 D 717522 CDS YP_005170011.1 378770278 11808805 617978..618628 1 NC_016804.1 putative thioredoxin protein 618628 11808805 BCGMEX_0540 Mycobacterium bovis BCG str. Mexico putative thioredoxin protein YP_005170011.1 617978 D 717522 CDS YP_005170012.1 378770279 11808806 618625..619404 1 NC_016804.1 cytochrome C biogenesis protein 619404 ccdA 11808806 ccdA Mycobacterium bovis BCG str. Mexico cytochrome C biogenesis protein YP_005170012.1 618625 D 717522 CDS YP_005170013.1 378770280 11808807 619437..621026 1 NC_016804.1 putative transmembrane protein 621026 11808807 BCGMEX_0542 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170013.1 619437 D 717522 CDS YP_005170014.1 378770281 11808808 621023..621997 1 NC_016804.1 cytochrome c-type biogenesis protein 621997 ccsA 11808808 ccsA Mycobacterium bovis BCG str. Mexico cytochrome c-type biogenesis protein YP_005170014.1 621023 D 717522 CDS YP_005170015.1 378770282 11808809 622039..623256 1 NC_016804.1 hypothetical protein 623256 11808809 BCGMEX_0544 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170015.1 622039 D 717522 CDS YP_005170016.1 378770283 11808810 623461..623778 1 NC_016804.1 hypothetical protein 623778 11808810 BCGMEX_0545 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170016.1 623461 D 717522 CDS YP_005170017.1 378770284 11808811 623925..625670 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS6 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion splits PE_PGRS6 into 2 parts, PE_PGRS6a and PE_PGRS6b, resulting in PE_PGRS6a having a different COOH part. There is also a 84 bp and a 9 bp insertion in PE_PGRS6a; PE-PGRS family protein 625670 PE_PGRS6a 11808811 PE_PGRS6a Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170017.1 623925 D 717522 CDS YP_005170018.1 378770285 11808813 complement(625699..626706) 1 NC_016804.1 3-oxoacyl-(acyl-carrier-protein) synthase III 626706 fabH 11808813 fabH Mycobacterium bovis BCG str. Mexico 3-oxoacyl-(acyl-carrier-protein) synthase III YP_005170018.1 625699 R 717522 CDS YP_005170019.1 378770286 11808814 complement(626788..627666) 1 NC_016804.1 1,4-dihydroxy-2-naphthoate octaprenyltransferase 627666 menA 11808814 menA Mycobacterium bovis BCG str. Mexico 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_005170019.1 626788 R 717522 CDS YP_005170020.1 378770287 11808815 627683..628477 1 NC_016804.1 5'-methylthioadenosine phosphorylase 628477 pnp 11808815 pnp Mycobacterium bovis BCG str. Mexico 5'-methylthioadenosine phosphorylase YP_005170020.1 627683 D 717522 CDS YP_005170021.1 378770288 11808816 628474..629514 1 NC_016804.1 UDP-glucose 4-epimerase 629514 galE3 11808816 galE3 Mycobacterium bovis BCG str. Mexico UDP-glucose 4-epimerase YP_005170021.1 628474 D 717522 CDS YP_005170022.1 378770289 11808817 complement(629524..630957) 1 NC_016804.1 putative integral membrane protein 630957 11808817 BCGMEX_0552c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170022.1 629524 R 717522 CDS YP_005170023.1 378770290 11808818 631266..632912 1 NC_016804.1 Differs from Rv0538 by 1aa, P228R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 632912 11808818 BCGMEX_0553 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170023.1 631266 D 717522 CDS YP_005170024.1 378770291 11808819 632969..633601 1 NC_016804.1 putative glycosyltransferase 633601 11808819 BCGMEX_0554 Mycobacterium bovis BCG str. Mexico putative glycosyltransferase YP_005170024.1 632969 D 717522 CDS YP_005170025.1 378770292 11808820 633598..634260 1 NC_016804.1 hypothetical protein 634260 11808820 BCGMEX_0555 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170025.1 633598 D 717522 CDS YP_005170026.1 378770293 11808821 complement(634281..635630) 1 NC_016804.1 Differs from Rv0541c by 1aa, V226I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 635630 11808821 BCGMEX_0556c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170026.1 634281 R 717522 CDS YP_005170027.1 378770294 11808822 complement(635642..636730) 1 NC_016804.1 putative O-succinylbenzoic acid--CoA ligase 636730 menE 11808822 menE Mycobacterium bovis BCG str. Mexico putative O-succinylbenzoic acid--CoA ligase YP_005170027.1 635642 R 717522 CDS YP_005170028.1 378770295 11808823 complement(636799..637101) 1 NC_016804.1 hypothetical protein 637101 11808823 BCGMEX_0558c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170028.1 636799 R 717522 CDS YP_005170029.1 378770296 11808824 complement(637161..637439) 1 NC_016804.1 transmembrane protein 637439 11808824 BCGMEX_0559c Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170029.1 637161 R 717522 CDS YP_005170030.1 378770297 11808825 complement(637436..638689) 1 NC_016804.1 Differs from Rv0545c by 1aa, S49P in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative low-affinity inorganic phosphate transporter 638689 pitA 11808825 pitA Mycobacterium bovis BCG str. Mexico putative low-affinity inorganic phosphate transporter YP_005170030.1 637436 R 717522 CDS YP_005170031.1 378770298 11808826 complement(638809..639195) 1 NC_016804.1 hypothetical protein 639195 11808826 BCGMEX_0561c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170031.1 638809 R 717522 CDS YP_005170032.1 378770299 11808827 complement(639258..640142) 1 NC_016804.1 putative oxidoreductase 640142 11808827 BCGMEX_0562c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170032.1 639258 R 717522 CDS YP_005170033.1 378770300 11808828 complement(640238..641182) 1 NC_016804.1 Naphthoate synthase 641182 menB 11808828 menB Mycobacterium bovis BCG str. Mexico Naphthoate synthase YP_005170033.1 640238 R 717522 CDS YP_005170034.1 378770301 11808830 complement(641558..641866) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0549c exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion, splits Rv0549c into 2 parts; hypothetical protein 641866 11808830 BCGMEX_0565c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170034.1 641558 R 717522 CDS YP_005170035.1 378770302 11808831 complement(641863..642129) 1 NC_016804.1 hypothetical protein 642129 11808831 BCGMEX_0566c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170035.1 641863 R 717522 CDS YP_005170036.1 378770303 11808832 complement(642321..644036) 1 NC_016804.1 putative fatty-acid-CoA ligase 644036 fadD8 11808832 fadD8 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005170036.1 642321 R 717522 CDS YP_005170037.1 378770304 11808833 644114..645718 1 NC_016804.1 Differs from Rv0552 and Mb0567 by 1aa, T144I in Mycobacterium bovis BCG Pasteur and BCG Mexico; hypothetical protein 645718 11808833 BCGMEX_0568 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170037.1 644114 D 717522 CDS YP_005170038.1 378770305 11808834 645715..646695 1 NC_016804.1 O-succinylbenzoate synthase 646695 menC 11808834 menC Mycobacterium bovis BCG str. Mexico O-succinylbenzoate synthase YP_005170038.1 645715 D 717522 CDS YP_005170039.1 378770306 11808835 646692..647480 1 NC_016804.1 putative peroxidase 647480 bpoC 11808835 bpoC Mycobacterium bovis BCG str. Mexico putative peroxidase YP_005170039.1 646692 D 717522 CDS YP_005170040.1 378770307 11808836 647523..649187 1 NC_016804.1 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 649187 menD 11808836 menD Mycobacterium bovis BCG str. Mexico 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_005170040.1 647523 D 717522 CDS YP_005170041.1 378770308 11808837 649184..649699 1 NC_016804.1 Differs from Rv0556 by 1aa, R15L in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 649699 11808837 BCGMEX_0572 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170041.1 649184 D 717522 CDS YP_005170042.1 378770309 11808838 649761..650897 1 NC_016804.1 Mannosyltransferase 650897 pimB 11808838 pimB Mycobacterium bovis BCG str. Mexico Mannosyltransferase YP_005170042.1 649761 D 717522 CDS YP_005170043.1 378770310 11808839 650914..651618 1 NC_016804.1 Ubiquinone/menaquinone biosynthesis methyltransferase 651618 ubiE 11808839 ubiE Mycobacterium bovis BCG str. Mexico Ubiquinone/menaquinone biosynthesis methyltransferase YP_005170043.1 650914 D 717522 CDS YP_005170044.1 378770311 11808840 complement(651632..651970) 1 NC_016804.1 putative secreted protein 651970 11808840 BCGMEX_0575c Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005170044.1 651632 R 717522 CDS YP_005170045.1 378770312 11808841 complement(652004..652729) 1 NC_016804.1 putative benzoquinone methyltransferase 652729 11808841 BCGMEX_0576c Mycobacterium bovis BCG str. Mexico putative benzoquinone methyltransferase YP_005170045.1 652004 R 717522 CDS YP_005170046.1 378770313 11808842 complement(652754..653980) 1 NC_016804.1 putative oxidoreductase 653980 11808842 BCGMEX_0577c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170046.1 652754 R 717522 CDS YP_005170047.1 378770314 11808843 653996..655003 1 NC_016804.1 putative polyprenyl-diphosphate synthase 655003 grcC1 11808843 grcC1 Mycobacterium bovis BCG str. Mexico putative polyprenyl-diphosphate synthase YP_005170047.1 653996 D 717522 CDS YP_005170048.1 378770315 11808844 655104..655964 1 NC_016804.1 putative protease htpX-like protein 655964 htpX 11808844 htpX Mycobacterium bovis BCG str. Mexico putative protease htpX-like protein YP_005170048.1 655104 D 717522 CDS YP_005170049.1 378770316 11808845 complement(656149..657174) 1 NC_016804.1 glycerol-3-phosphate dehydrogenase 2(NAD(P)+) 657174 gpdA1 11808845 gpdA1 Mycobacterium bovis BCG str. Mexico glycerol-3-phosphate dehydrogenase 2(NAD(P)+) YP_005170049.1 656149 R 717522 CDS YP_005170050.1 378770317 11808846 complement(657235..658695) 1 NC_016804.1 putative monooxygenase 658695 11808846 BCGMEX_0581c Mycobacterium bovis BCG str. Mexico putative monooxygenase YP_005170050.1 657235 R 717522 CDS YP_005170051.1 378770318 11808847 complement(658773..659264) 1 NC_016804.1 hypothetical protein 659264 11808847 BCGMEX_0582c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170051.1 658773 R 717522 CDS YP_005170052.1 378770319 11808849 659546..660565 1 NC_016804.1 Differs from Rv0567 by 1aa, L201F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative methyltransferase/methylase 660565 11808849 BCGMEX_0583 Mycobacterium bovis BCG str. Mexico putative methyltransferase/methylase YP_005170052.1 659546 D 717522 CDS YP_005170053.1 378770320 11808850 660675..662093 1 NC_016804.1 Differs from Rv0568 and Mb0583 by 1aa, E120G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytochrome P450 135B1 662093 cyp135B1 11808850 cyp135B1 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 135B1 YP_005170053.1 660675 D 717522 CDS YP_005170054.1 378770321 11808851 662228..662494 1 NC_016804.1 hypothetical protein 662494 11808851 BCGMEX_0585 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170054.1 662228 D 717522 CDS YP_005170055.1 378770322 11808852 662520..664652 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion leads to a product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; ribonucleoside-diphosphate reductase 664652 nrdZ 11808852 nrdZ Mycobacterium bovis BCG str. Mexico ribonucleoside-diphosphate reductase YP_005170055.1 662520 D 717522 CDS YP_005170056.1 378770323 11808853 complement(664711..666042) 1 NC_016804.1 Differs from Rv0571c and Mb0586c by 1aa, L258F in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 666042 11808853 BCGMEX_0587c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170056.1 664711 R 717522 CDS YP_005170057.1 378770324 11808854 complement(666266..666607) 1 NC_016804.1 Differs from Rv0572c by 1aa, L31F in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 666607 11808854 BCGMEX_0588c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170057.1 666266 R 717522 CDS YP_005170058.1 378770325 11808855 complement(667075..668466) 1 NC_016804.1 nicotinate phosphoribosyltransferase 668466 pncB2 11808855 pncB2 Mycobacterium bovis BCG str. Mexico nicotinate phosphoribosyltransferase YP_005170058.1 667075 R 717522 CDS YP_005170059.1 378770326 11808856 complement(668476..669618) 1 NC_016804.1 Differs from Rv0574c by 1aa, K4N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 669618 11808856 BCGMEX_0590c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170059.1 668476 R 717522 CDS YP_005170060.1 378770327 11808857 complement(669834..670970) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base insertion leads to a shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; putative oxidoreductase 670970 11808857 BCGMEX_0591c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170060.1 669834 R 717522 CDS YP_005170061.1 378770328 11808858 671073..672377 1 NC_016804.1 Differs from Rv0576 by 1aa, H233R in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, ArsR family 672377 11808858 BCGMEX_0592 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, ArsR family YP_005170061.1 671073 D 717522 CDS YP_005170062.1 378770329 11808859 672391..673176 1 NC_016804.1 putative 27 kDa antigen 673176 cfp30B 11808859 cfp30B Mycobacterium bovis BCG str. Mexico putative 27 kDa antigen YP_005170062.1 672391 D 717522 CDS YP_005170063.1 378770330 11808860 complement(673221..677132) 1 NC_016804.1 Differs from Rv0578c and from Mb0593c by 3aa, there are deleted in Mycobacterium bovis BCG Pasteur and BCG Mexico; PE-PGRS family protein 677132 PE_PGRS7 11808860 PE_PGRS7 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170063.1 673221 R 717522 CDS YP_005170064.1 378770331 11808861 677454..678212 1 NC_016804.1 hypothetical protein 678212 11808861 BCGMEX_0595 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170064.1 677454 D 717522 CDS YP_005170065.1 378770332 11808862 complement(678341..678832) 1 NC_016804.1 hypothetical protein 678832 11808862 BCGMEX_0596c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170065.1 678341 R 717522 CDS YP_005170066.1 378770333 11808863 678926..679141 1 NC_016804.1 hypothetical protein 679141 11808863 BCGMEX_0597 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170066.1 678926 D 717522 CDS YP_005170067.1 378770334 11808864 679138..679545 1 NC_016804.1 hypothetical protein 679545 11808864 BCGMEX_0598 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170067.1 679138 D 717522 CDS YP_005170068.1 378770335 11808865 complement(679605..680291) 1 NC_016804.1 putative lipoprotein 680291 lpqN 11808865 lpqN Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170068.1 679605 R 717522 CDS YP_005170069.1 378770336 11808866 680445..683078 1 NC_016804.1 Differs from Rv0584 by 1aa G90D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 683078 11808866 BCGMEX_0600 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170069.1 680445 D 717522 CDS YP_005170070.1 378770337 11808867 complement(683101..685488) 1 NC_016804.1 Differs from Rv0585c by 1aa V438I and from Mb0600c by 2aa M150I and V438I in BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 685488 11808867 BCGMEX_0601c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170070.1 683101 R 717522 CDS YP_005170071.1 378770338 11808868 685626..686348 1 NC_016804.1 putative transcriptional regulatory protein, GntR family 686348 11808868 BCGMEX_0602 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, GntR family YP_005170071.1 685626 D 717522 CDS YP_005170072.1 378770339 11808869 686345..687142 1 NC_016804.1 putative integral membrane protein 687142 yrbE2A 11808869 yrbE2A Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170072.1 686345 D 717522 CDS YP_005170073.1 378770340 11808870 687144..688031 1 NC_016804.1 putative integral membrane protein 688031 yrbE2B 11808870 yrbE2B Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170073.1 687144 D 717522 CDS YP_005170074.1 378770341 11808871 688037..689251 1 NC_016804.1 Differs from Rv0589 by 1aa S51F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 689251 mce2A 11808871 mce2A Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005170074.1 688037 D 717522 CDS YP_005170075.1 378770342 11808872 689248..690279 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, mce2B and Rv0590A are 2 genes, most likely to be linked. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, an in-frame insertion of a single base leads to a single product; MCE-family protein 690279 mce2B 11808872 mce2B Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005170075.1 689248 D 717522 CDS YP_005170076.1 378770343 11808873 690276..691721 1 NC_016804.1 Differs from Rv0591 by 2aa M49T and N398T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 691721 mce2C 11808873 mce2C Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005170076.1 690276 D 717522 CDS YP_005170077.1 378770344 11808874 691718..693268 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, mce2D exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift occurs in a strech of C (7 for H37Rv, 8 for Mycobactrium bovis and 9 for Mycobacterium bovis BCG). This leads to mceDa genes with different COOH parts and a remnant mc2Db pseudogene; MCE-family protein 693268 mce2Da 11808874 mce2Da Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005170077.1 691718 D 717522 CDS YP_005170078.1 378770345 11808875 693243..694451 1 NC_016804.1 In Mycobacterium bovis, a single base transition introducing a stop codon, leads to the formation of a truncated product compared to its homolog in Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico (188 aa versus 402 aa); putative MCE-family lipoprotein 694451 lprL 11808875 lprL Mycobacterium bovis BCG str. Mexico putative MCE-family lipoprotein YP_005170078.1 693243 D 717522 CDS YP_005170079.1 378770346 11808876 694456..696006 1 NC_016804.1 MCE-family protein 696006 mce2F 11808876 mce2F Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005170079.1 694456 D 717522 CDS YP_005170080.1 378770347 11808877 complement(696058..696450) 1 NC_016804.1 hypothetical protein 696450 11808877 BCGMEX_0611c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170080.1 696058 R 717522 CDS YP_005170081.1 378770348 11808878 complement(696447..696704) 1 NC_016804.1 hypothetical protein 696704 11808878 BCGMEX_0612c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170081.1 696447 R 717522 CDS YP_005170082.1 378770349 11808879 complement(696887..698122) 1 NC_016804.1 hypothetical protein 698122 11808879 BCGMEX_0613c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170082.1 696887 R 717522 CDS YP_005170083.1 378770350 11808880 complement(698373..698786) 1 NC_016804.1 hypothetical protein 698786 11808880 BCGMEX_0614c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170083.1 698373 R 717522 CDS YP_005170084.1 378770351 11808881 complement(698783..699019) 1 NC_016804.1 hypothetical protein 699019 11808881 BCGMEX_0615c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170084.1 698783 R 717522 CDS YP_005170085.1 378770352 11808882 complement(699123..699629) 1 NC_016804.1 Second part; putative two component sensor kinase 699629 11808882 BCGMEX_0616c Mycobacterium bovis BCG str. Mexico putative two component sensor kinase YP_005170085.1 699123 R 717522 CDS YP_005170086.1 378770353 11808883 complement(699743..700213) 1 NC_016804.1 First part; putative two component sensor kinase 700213 11808883 BCGMEX_0617c Mycobacterium bovis BCG str. Mexico putative two component sensor kinase YP_005170086.1 699743 R 717522 CDS YP_005170087.1 378770354 11808884 complement(700257..701018) 1 NC_016804.1 Differs from Rv0602c by 1aa I28V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative two component DNA binding transcriptional regulatory protein 701018 tcrA 11808884 tcrA Mycobacterium bovis BCG str. Mexico putative two component DNA binding transcriptional regulatory protein YP_005170087.1 700257 R 717522 CDS YP_005170088.1 378770355 11808885 701075..701386 1 NC_016804.1 Differs from Mb0619 by 2aa P77A and E96K in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 701386 11808885 BCGMEX_0619 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170088.1 701075 D 717522 CDS YP_005170089.1 378770356 11808886 701458..702408 1 NC_016804.1 Differs from Rv0604 by 1aa P180S in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 702408 lpqO 11808886 lpqO Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170089.1 701458 D 717522 CDS YP_005170090.1 378770357 11808887 702625..703233 1 NC_016804.1 putative resolvase 703233 11808887 BCGMEX_0621 Mycobacterium bovis BCG str. Mexico putative resolvase YP_005170090.1 702625 D 717522 CDS YP_005170091.1 378770358 11808888 703235..703978 1 NC_016804.1 putative transposase 703978 11808888 BCGMEX_0622 Mycobacterium bovis BCG str. Mexico putative transposase YP_005170091.1 703235 D 717522 CDS YP_005170092.1 378770359 11808889 704032..704418 1 NC_016804.1 hypothetical protein 704418 11808889 BCGMEX_0623 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170092.1 704032 D 717522 CDS YP_005170093.1 378770360 11808890 704463..704708 1 NC_016804.1 hypothetical protein 704708 11808890 BCGMEX_0624 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170093.1 704463 D 717522 CDS YP_005170094.1 378770361 11808891 704705..705106 1 NC_016804.1 hypothetical protein 705106 11808891 BCGMEX_0625 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170094.1 704705 D 717522 CDS YP_005170095.1 378770362 11808892 705204..705431 1 NC_016804.1 hypothetical protein 705431 11808892 BCGMEX_0626 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170095.1 705204 D 717522 CDS YP_005170096.1 378770363 11808893 complement(705971..707128) 1 NC_016804.1 Differs from Rv0610c by 1aa S103N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 707128 11808893 BCGMEX_0627c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170096.1 705971 R 717522 CDS YP_005170097.1 378770364 11808894 complement(707180..707563) 1 NC_016804.1 hypothetical protein 707563 11808894 BCGMEX_0628c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170097.1 707180 R 717522 CDS YP_005170098.1 378770365 11808895 707543..708148 1 NC_016804.1 hypothetical protein 708148 11808895 BCGMEX_0629 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170098.1 707543 D 717522 CDS YP_005170099.1 378770366 11808896 complement(708167..710734) 1 NC_016804.1 hypothetical protein 710734 11808896 BCGMEX_0630c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170099.1 708167 R 717522 CDS YP_005170100.1 378770367 11808897 710575..711567 1 NC_016804.1 hypothetical protein 711567 11808897 BCGMEX_0631 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170100.1 710575 D 717522 CDS YP_005170101.1 378770368 11808898 711564..711806 1 NC_016804.1 putative integral membrane protein 711806 11808898 BCGMEX_0632 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170101.1 711564 D 717522 CDS YP_005170102.1 378770369 11808899 complement(711803..712069) 1 NC_016804.1 hypothetical protein 712069 11808899 BCGMEX_0633c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170102.1 711803 R 717522 CDS YP_005170103.1 378770370 11808900 712001..712228 1 NC_016804.1 hypothetical protein 712228 11808900 BCGMEX_0634 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170103.1 712001 D 717522 CDS YP_005170104.1 378770371 11808901 712225..712626 1 NC_016804.1 hypothetical protein 712626 11808901 BCGMEX_0635 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170104.1 712225 D 717522 CDS YP_005170105.1 378770372 11808902 712755..713939 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, galT is split into 2 parts, galT' and 'galT. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, an in-frame insertion of a single base leads to a single product. Differs from Mb0635 by 1aa R183G and from Rv0619 by 1aa A397T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative galactose-1-phosphate uridylyltransferase 713939 galT 11808902 galT Mycobacterium bovis BCG str. Mexico putative galactose-1-phosphate uridylyltransferase YP_005170105.1 712755 D 717522 CDS YP_005170106.1 378770373 11808903 713936..715027 1 NC_016804.1 Differs from Rv0620 by 1aa R199C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; galactokinase 715027 galK 11808903 galK Mycobacterium bovis BCG str. Mexico galactokinase YP_005170106.1 713936 D 717522 CDS YP_005170107.1 378770374 11808904 715422..716579 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transition leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (385 aa versus 354 aa); hypothetical protein 716579 11808904 BCGMEX_0638 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170107.1 715422 D 717522 CDS YP_005170108.1 378770375 11808905 716590..717537 1 NC_016804.1 hypothetical protein 717537 11808905 BCGMEX_0639 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170108.1 716590 D 717522 CDS YP_005170109.1 378770376 11808906 717630..717884 1 NC_016804.1 hypothetical protein 717884 11808906 BCGMEX_0640 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170109.1 717630 D 717522 CDS YP_005170110.1 378770377 11808907 717884..718279 1 NC_016804.1 hypothetical protein 718279 11808907 BCGMEX_0641 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170110.1 717884 D 717522 CDS YP_005170111.1 378770378 11808908 complement(718373..719113) 1 NC_016804.1 hypothetical protein 719113 11808908 BCGMEX_0642c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170111.1 718373 R 717522 CDS YP_005170112.1 378770379 11808909 719245..719505 1 NC_016804.1 hypothetical protein 719505 11808909 BCGMEX_0643 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170112.1 719245 D 717522 CDS YP_005170113.1 378770380 11808910 719502..719909 1 NC_016804.1 hypothetical protein 719909 11808910 BCGMEX_0644 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170113.1 719502 D 717522 CDS YP_005170114.1 378770381 11808911 complement(719981..721132) 1 NC_016804.1 hypothetical protein 721132 11808911 BCGMEX_0645c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170114.1 719981 R 717522 CDS YP_005170115.1 378770382 11808912 complement(721225..722952) 1 NC_016804.1 Differs from Rv0629c by 1aa A536T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative exodeoxyribonuclease V alpha chain 722952 recD 11808912 recD Mycobacterium bovis BCG str. Mexico putative exodeoxyribonuclease V alpha chain YP_005170115.1 721225 R 717522 CDS YP_005170116.1 378770383 11808914 complement(723539..726232) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, recB exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion (G-*) splits recB into 2 parts, recBa and recBb. Differs from Mb0647c by 1aa H514R and from Rv0630c by 3aa L74V, H514R and F811V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative exodeoxyribonuclease V beta chain 726232 recBa 11808914 recBa Mycobacterium bovis BCG str. Mexico putative exodeoxyribonuclease V beta chain YP_005170116.1 723539 R 717522 CDS YP_005170117.1 378770384 11808915 complement(726232..729525) 1 NC_016804.1 Differs from Rv0631c by 1aa E329G and from Mb0648c by 1aa P858L in BCG Pasteur, BCG Tokyo and BCG Mexico; putative exodeoxyribonuclease V gamma chain 729525 recC 11808915 recC Mycobacterium bovis BCG str. Mexico putative exodeoxyribonuclease V gamma chain YP_005170117.1 726232 R 717522 CDS YP_005170118.1 378770385 11808916 complement(729802..730497) 1 NC_016804.1 Differs from Rv0632c and Mb0649c by 1aa M148V in Mycobacterium bovis BCG Pasteur; Enoyl-CoA hydratase 730497 echA3 11808916 echA3 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170118.1 729802 R 717522 CDS YP_005170119.1 378770386 11808917 complement(730546..731376) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 9 bp deletion (CGGGTGCGC-*) leads to shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (Rv0633c) (276 aa versus 279 aa); hypothetical protein 731376 11808917 BCGMEX_0651c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170119.1 730546 R 717522 CDS YP_005170120.1 378770387 11808918 complement(731530..732243) 1 NC_016804.1 putative glyoxalase II 732243 11808918 BCGMEX_0652c Mycobacterium bovis BCG str. Mexico putative glyoxalase II YP_005170120.1 731530 R 717522 CDS YP_005170121.1 378770388 11808919 732323..732574 1 NC_016804.1 hypothetical protein 732574 11808919 BCGMEX_0653 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170121.1 732323 D 717522 CDS YP_005170122.1 378770389 11808922 732922..733089 1 NC_016804.1 50S ribosomal protein L33 733089 rpmG2 11808922 rpmG2 Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L33 YP_005170122.1 732922 D 717522 CDS YP_005170123.1 378770390 11808923 733140..733616 1 NC_016804.1 hypothetical protein 733616 11808923 BCGMEX_0655 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170123.1 733140 D 717522 CDS YP_005170124.1 378770391 11808924 733603..734031 1 NC_016804.1 Differs from Rv0636 by 1aa A53T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 734031 11808924 BCGMEX_0656 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170124.1 733603 D 717522 CDS YP_005170125.1 378770392 11808925 734035..734535 1 NC_016804.1 hypothetical protein 734535 11808925 BCGMEX_0657 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170125.1 734035 D 717522 CDS YP_005170126.1 378770393 11808927 734947..735432 1 NC_016804.1 preprotein translocase subunit SecE 735432 secE 11808927 secE Mycobacterium bovis BCG str. Mexico preprotein translocase subunit SecE YP_005170126.1 734947 D 717522 CDS YP_005170127.1 378770394 11808928 735464..736180 1 NC_016804.1 Transcription antitermination protein 736180 nusG 11808928 nusG Mycobacterium bovis BCG str. Mexico Transcription antitermination protein YP_005170127.1 735464 D 717522 CDS YP_005170128.1 378770395 11808929 736232..736660 1 NC_016804.1 50S ribosomal protein L11 736660 rplK 11808929 rplK Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L11 YP_005170128.1 736232 D 717522 CDS YP_005170129.1 378770396 11808930 736727..737434 1 NC_016804.1 Differs from Rv0641 by 1aa A117T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 50S ribosomal protein L1 737434 rplA 11808930 rplA Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L1 YP_005170129.1 736727 D 717522 CDS YP_005170130.1 378770397 11808931 complement(737508..738413) 1 NC_016804.1 Differs from Rv0642c by 1aa L95F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; methoxy mycolic acid synthase 4 738413 mmaA4 11808931 mmaA4 Mycobacterium bovis BCG str. Mexico methoxy mycolic acid synthase 4 YP_005170130.1 737508 R 717522 CDS YP_005170131.1 378770398 11808932 complement(738478..739359) 1 NC_016804.1 Differ from Rv0643c by 1aa, D98G in BCG Pasteur and BCG Mexico.; methoxy mycolic acid synthase 3 739359 mmaA3 11808932 mmaA3 Mycobacterium bovis BCG str. Mexico methoxy mycolic acid synthase 3 YP_005170131.1 738478 R 717522 CDS YP_005170132.1 378770399 11808933 complement(739507..740370) 1 NC_016804.1 Differs from Rv0644c by 1aa L114R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; methoxy mycolic acid synthase 2 740370 mmaA2 11808933 mmaA2 Mycobacterium bovis BCG str. Mexico methoxy mycolic acid synthase 2 YP_005170132.1 739507 R 717522 CDS YP_005170133.1 378770400 11808934 complement(740537..741397) 1 NC_016804.1 methoxy mycolic acid synthase 1 741397 mmaA1 11808934 mmaA1 Mycobacterium bovis BCG str. Mexico methoxy mycolic acid synthase 1 YP_005170133.1 740537 R 717522 CDS YP_005170134.1 378770401 11808935 complement(741444..742349) 1 NC_016804.1 putative lipase/esterase 742349 lipG 11808935 lipG Mycobacterium bovis BCG str. Mexico putative lipase/esterase YP_005170134.1 741444 R 717522 CDS YP_005170135.1 378770402 11808936 complement(742361..743827) 1 NC_016804.1 Differs from Rv0647c by 1aa T293A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 743827 11808936 BCGMEX_0667c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170135.1 742361 R 717522 CDS YP_005170136.1 378770403 11808937 743913..748109 1 NC_016804.1 Differs from Rv0648 by 1aa L200S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; alpha-mannosidase 748109 11808937 BCGMEX_0668 Mycobacterium bovis BCG str. Mexico alpha-mannosidase YP_005170136.1 743913 D 717522 CDS YP_005170137.1 378770404 11808938 748106..748780 1 NC_016804.1 putative Malonyl CoA-acyl carrier protein transacylase 748780 fabD2 11808938 fabD2 Mycobacterium bovis BCG str. Mexico putative Malonyl CoA-acyl carrier protein transacylase YP_005170137.1 748106 D 717522 CDS YP_005170138.1 378770405 11808939 748780..749688 1 NC_016804.1 putative sugar kinase 749688 11808939 BCGMEX_0670 Mycobacterium bovis BCG str. Mexico putative sugar kinase YP_005170138.1 748780 D 717522 CDS YP_005170139.1 378770406 11808940 750019..750555 1 NC_016804.1 50S ribosomal protein L10 750555 rplJ 11808940 rplJ Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L10 YP_005170139.1 750019 D 717522 CDS YP_005170140.1 378770407 11808941 750592..750984 1 NC_016804.1 putative 50S ribosomal protein L7/L12 750984 rplL 11808941 rplL Mycobacterium bovis BCG str. Mexico putative 50S ribosomal protein L7/L12 YP_005170140.1 750592 D 717522 CDS YP_005170141.1 378770408 11808942 complement(750977..751672) 1 NC_016804.1 putative transcriptional regulatory protein, probably tetR-family 751672 11808942 BCGMEX_0673c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, probably tetR-family YP_005170141.1 750977 R 717522 CDS YP_005170142.1 378770409 11808943 751743..753248 1 NC_016804.1 putative dioxygenase 753248 11808943 BCGMEX_0674 Mycobacterium bovis BCG str. Mexico putative dioxygenase YP_005170142.1 751743 D 717522 CDS YP_005170143.1 378770410 11808944 753260..754339 1 NC_016804.1 putative ribonucleotide-transport ATP-binding protein ABC transporter 754339 mkl 11808944 mkl Mycobacterium bovis BCG str. Mexico putative ribonucleotide-transport ATP-binding protein ABC transporter YP_005170143.1 753260 D 717522 CDS YP_005170144.1 378770411 11808945 complement(754727..755110) 1 NC_016804.1 hypothetical protein 755110 11808945 BCGMEX_0676c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170144.1 754727 R 717522 CDS YP_005170145.1 378770412 11808946 complement(755205..755360) 1 NC_016804.1 hypothetical protein 755360 11808946 BCGMEX_0677c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170145.1 755205 R 717522 CDS YP_005170146.1 378770413 11808947 complement(755436..756152) 1 NC_016804.1 Differs from Rv0658c by 1aa P75L in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 756152 11808947 BCGMEX_0678c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170146.1 755436 R 717522 CDS YP_005170147.1 378770414 11808948 complement(756428..756736) 1 NC_016804.1 hypothetical protein 756736 11808948 BCGMEX_0679c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170147.1 756428 R 717522 CDS YP_005170148.1 378770415 11808949 complement(756723..756968) 1 NC_016804.1 hypothetical protein 756968 11808949 BCGMEX_0680c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170148.1 756723 R 717522 CDS YP_005170149.1 378770416 11808950 complement(757078..757515) 1 NC_016804.1 hypothetical protein 757515 11808950 BCGMEX_0681c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170149.1 757078 R 717522 CDS YP_005170150.1 378770417 11808951 complement(757512..757880) 1 NC_016804.1 hypothetical protein 757880 11808951 BCGMEX_0682c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170150.1 757512 R 717522 CDS YP_005170151.1 378770418 11808952 757880..760243 1 NC_016804.1 Differs from Rv0663 by 1aa G349D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative arylsulfatase 760243 atsD 11808952 atsD Mycobacterium bovis BCG str. Mexico putative arylsulfatase YP_005170151.1 757880 D 717522 CDS YP_005170152.1 378770419 11808953 760275..760547 1 NC_016804.1 hypothetical protein 760547 11808953 BCGMEX_0684 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170152.1 760275 D 717522 CDS YP_005170153.1 378770420 11808954 760544..760882 1 NC_016804.1 hypothetical protein 760882 11808954 BCGMEX_0685 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170153.1 760544 D 717522 CDS YP_005170154.1 378770421 11808955 760879..761052 1 NC_016804.1 hypothetical protein 761052 11808955 BCGMEX_0686 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170154.1 760879 D 717522 CDS YP_005170155.1 378770422 11808956 761550..765068 1 NC_016804.1 DNA-directed RNA polymerase subunit beta 765068 rpoB 11808956 rpoB Mycobacterium bovis BCG str. Mexico DNA-directed RNA polymerase subunit beta YP_005170155.1 761550 D 717522 CDS YP_005170156.1 378770423 11808957 765113..769063 1 NC_016804.1 Differs from Rv0668 by 2aa A68V, and P69R in BCG Tokyo, by 1aa P69R in BCG Pasteur and BCG Mexico; DNA-directed RNA polymerase beta' 769063 rpoC 11808957 rpoC Mycobacterium bovis BCG str. Mexico DNA-directed RNA polymerase beta' YP_005170156.1 765113 D 717522 CDS YP_005170157.1 378770424 11808958 complement(769427..771340) 1 NC_016804.1 Differs from Rv0669c by 1aa P146S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative hydrolase 771340 11808958 BCGMEX_0689c Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005170157.1 769427 R 717522 CDS YP_005170158.1 378770425 11808959 771535..772293 1 NC_016804.1 Endonuclease IV 772293 end 11808959 end Mycobacterium bovis BCG str. Mexico Endonuclease IV YP_005170158.1 771535 D 717522 CDS YP_005170159.1 378770426 11808960 772325..773167 1 NC_016804.1 putative lipoprotein 773167 lpqP 11808960 lpqP Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170159.1 772325 D 717522 CDS YP_005170160.1 378770427 11808961 773227..774855 1 NC_016804.1 putative Acyl-CoA dehydrogenase 774855 fadE8 11808961 fadE8 Mycobacterium bovis BCG str. Mexico putative Acyl-CoA dehydrogenase YP_005170160.1 773227 D 717522 CDS YP_005170161.1 378770428 11808962 774866..775804 1 NC_016804.1 Enoyl-CoA hydratase 775804 echA4 11808962 echA4 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170161.1 774866 D 717522 CDS YP_005170162.1 378770429 11808963 775807..776529 1 NC_016804.1 hypothetical protein 776529 11808963 BCGMEX_0694 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170162.1 775807 D 717522 CDS YP_005170163.1 378770430 11808964 776526..777317 1 NC_016804.1 enoyl-CoA hydratase 777317 echA5 11808964 echA5 Mycobacterium bovis BCG str. Mexico enoyl-CoA hydratase YP_005170163.1 776526 D 717522 CDS YP_005170164.1 378770431 11808965 complement(777329..780223) 1 NC_016804.1 Differs from Rv0676c by 2aa I794T and V948I in Mycobacterium bovis BCG Pasteur anbd BCG Mexico, by 3aa I794T, I906V, V948I in Mycobacterium bovis BCG Tokyo.; putative transmembrane transport protein 780223 mmpL5 11808965 mmpL5 Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005170164.1 777329 R 717522 CDS YP_005170165.1 378770432 11808966 complement(780220..780648) 1 NC_016804.1 putative membrane protein mmpS5 780648 mmpS5 11808966 mmpS5 Mycobacterium bovis BCG str. Mexico putative membrane protein mmpS5 YP_005170165.1 780220 R 717522 CDS YP_005170166.1 378770433 11808967 780733..781230 1 NC_016804.1 hypothetical protein 781230 11808967 BCGMEX_0698 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170166.1 780733 D 717522 CDS YP_005170167.1 378770434 11808968 complement(781286..781783) 1 NC_016804.1 putative threonine rich protein 781783 11808968 BCGMEX_0699c Mycobacterium bovis BCG str. Mexico putative threonine rich protein YP_005170167.1 781286 R 717522 CDS YP_005170168.1 378770435 11808969 complement(781785..782159) 1 NC_016804.1 putative transmembrane protein 782159 11808969 BCGMEX_0700c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170168.1 781785 R 717522 CDS YP_005170169.1 378770436 11808970 782464..783054 1 NC_016804.1 putative transcriptional regulatory protein, TetR-family 783054 11808970 BCGMEX_0701 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR-family YP_005170169.1 782464 D 717522 CDS YP_005170170.1 378770437 11808971 783303..783677 1 NC_016804.1 30s ribosomal protein S12 783677 rpsL 11808971 rpsL Mycobacterium bovis BCG str. Mexico 30s ribosomal protein S12 YP_005170170.1 783303 D 717522 CDS YP_005170171.1 378770438 11808972 783677..784147 1 NC_016804.1 30s ribosomal protein S7 784147 rpsG 11808972 rpsG Mycobacterium bovis BCG str. Mexico 30s ribosomal protein S7 YP_005170171.1 783677 D 717522 CDS YP_005170172.1 378770439 11808973 784228..786333 1 NC_016804.1 Elongation factor G 786333 fusA1 11808973 fusA1 Mycobacterium bovis BCG str. Mexico Elongation factor G YP_005170172.1 784228 D 717522 CDS YP_005170173.1 378770440 11808974 786564..787754 1 NC_016804.1 Elongation factor Tu 787754 tuf 11808974 tuf Mycobacterium bovis BCG str. Mexico Elongation factor Tu YP_005170173.1 786564 D 717522 CDS YP_005170174.1 378770441 11808975 787892..788689 1 NC_016804.1 Differs from Rv0686 by 1aa S82I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 788689 11808975 BCGMEX_0706 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170174.1 787892 D 717522 CDS YP_005170175.1 378770442 11808976 788842..789669 1 NC_016804.1 3-ketoacyl-ACP reductase 789669 fabG 11808976 fabG Mycobacterium bovis BCG str. Mexico 3-ketoacyl-ACP reductase YP_005170175.1 788842 D 717522 CDS YP_005170176.1 378770443 11808977 789683..790903 1 NC_016804.1 putative ferredoxin reductase 790903 11808977 BCGMEX_0708 Mycobacterium bovis BCG str. Mexico putative ferredoxin reductase YP_005170176.1 789683 D 717522 CDS YP_005170177.1 378770444 11808978 complement(790900..791154) 1 NC_016804.1 hypothetical protein 791154 11808978 BCGMEX_0709c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170177.1 790900 R 717522 CDS YP_005170178.1 378770445 11808979 complement(791767..792816) 1 NC_016804.1 hypothetical protein 792816 11808979 BCGMEX_0710c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170178.1 791767 R 717522 CDS YP_005170179.1 378770446 11808980 complement(792813..793409) 1 NC_016804.1 putative transcriptional regulatory protein 793409 11808980 BCGMEX_0711c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170179.1 792813 R 717522 CDS YP_005170180.1 378770447 11808981 793574..793903 1 NC_016804.1 hypothetical protein 793903 11808981 BCGMEX_0712 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170180.1 793574 D 717522 CDS YP_005170181.1 378770448 11808982 793900..795075 1 NC_016804.1 putative coenzyme pqq synthesis protein E 795075 pqqE 11808982 pqqE Mycobacterium bovis BCG str. Mexico putative coenzyme pqq synthesis protein E YP_005170181.1 793900 D 717522 CDS YP_005170182.1 378770449 11808983 795078..796268 1 NC_016804.1 Cytochrome; putative L-lactate dehydrogenase 796268 lldD1 11808983 lldD1 Mycobacterium bovis BCG str. Mexico putative L-lactate dehydrogenase YP_005170182.1 795078 D 717522 CDS YP_005170183.1 378770450 11808984 796458..797213 1 NC_016804.1 hypothetical protein 797213 11808984 BCGMEX_0715 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170183.1 796458 D 717522 CDS YP_005170184.1 378770451 11808985 797262..798674 1 NC_016804.1 putative membran sugar transferase 798674 11808985 BCGMEX_0716 Mycobacterium bovis BCG str. Mexico putative membran sugar transferase YP_005170184.1 797262 D 717522 CDS YP_005170185.1 378770452 11808986 798676..800115 1 NC_016804.1 putative dehydrogenase 800115 11808986 BCGMEX_0717 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005170185.1 798676 D 717522 CDS YP_005170186.1 378770453 11808987 800576..800905 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0698 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion (C-*) splits Rv0698 into 2 parts, Mb0717 and Mb0718; hypothetical protein 800905 11808987 BCGMEX_0718 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170186.1 800576 D 717522 CDS YP_005170187.1 378770454 11808988 800953..801186 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0698 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion (C-*) splits Rv0698 into 2 parts, Mb0717 and Mb0718; hypothetical protein 801186 11808988 BCGMEX_0719 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170187.1 800953 D 717522 CDS YP_005170188.1 378770455 11808989 801371..801592 1 NC_016804.1 hypothetical protein 801592 11808989 BCGMEX_0720 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170188.1 801371 D 717522 CDS YP_005170189.1 378770456 11808990 802229..802534 1 NC_016804.1 30S ribosomal protein S10 802534 rpsJ 11808990 rpsJ Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S10 YP_005170189.1 802229 D 717522 CDS YP_005170190.1 378770457 11808991 802551..803204 1 NC_016804.1 50S ribosomal protein L3 803204 rplC 11808991 rplC Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L3 YP_005170190.1 802551 D 717522 CDS YP_005170191.1 378770458 11808992 803204..803875 1 NC_016804.1 50S ribosomal protein L4 803875 rplD 11808992 rplD Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L4 YP_005170191.1 803204 D 717522 CDS YP_005170192.1 378770459 11808993 803875..804177 1 NC_016804.1 50S ribosomal protein L23 804177 rplW 11808993 rplW Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L23 YP_005170192.1 803875 D 717522 CDS YP_005170193.1 378770460 11808994 804324..805166 1 NC_016804.1 50S ribosomal protein L2 805166 rplB 11808994 rplB Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L2 YP_005170193.1 804324 D 717522 CDS YP_005170194.1 378770461 11808995 805207..805488 1 NC_016804.1 30S ribosomal protein S19 805488 rpsS 11808995 rpsS Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S19 YP_005170194.1 805207 D 717522 CDS YP_005170195.1 378770462 11808996 805485..806078 1 NC_016804.1 50S ribosomal protein L22 806078 rplV 11808996 rplV Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L22 YP_005170195.1 805485 D 717522 CDS YP_005170196.1 378770463 11808997 806078..806902 1 NC_016804.1 30S ribosomal protein S3 806902 rpsC 11808997 rpsC Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S3 YP_005170196.1 806078 D 717522 CDS YP_005170197.1 378770464 11808998 806906..807322 1 NC_016804.1 50S ribosomal protein L16 807322 rplP 11808998 rplP Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L16 YP_005170197.1 806906 D 717522 CDS YP_005170198.1 378770465 11808999 807322..807555 1 NC_016804.1 50S ribosomal protein L29 807555 rpmC 11808999 rpmC Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L29 YP_005170198.1 807322 D 717522 CDS YP_005170199.1 378770466 11809000 807552..807962 1 NC_016804.1 30S ribosomal protein S17 807962 rpsQ 11809000 rpsQ Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S17 YP_005170199.1 807552 D 717522 CDS YP_005170200.1 378770467 11809001 808131..810494 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, atsA exists as a single gene. In Mycobacterium bovis, a single base transversion (G-T), introducing a stop codon, splits atsA into 2 parts, atsAa and atsA; putative arylsulfatase 810494 atsA 11809001 atsA Mycobacterium bovis BCG str. Mexico putative arylsulfatase YP_005170200.1 808131 D 717522 CDS YP_005170201.1 378770468 11809002 810542..811441 1 NC_016804.1 hypothetical protein 811441 11809002 BCGMEX_0733 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170201.1 810542 D 717522 CDS YP_005170202.1 378770469 11809003 811742..812683 1 NC_016804.1 transmembrane protein 812683 11809003 BCGMEX_0734 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170202.1 811742 D 717522 CDS YP_005170203.1 378770470 11809004 813169..813537 1 NC_016804.1 50S ribosomal protein L14 813537 rplN 11809004 rplN Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L14 YP_005170203.1 813169 D 717522 CDS YP_005170204.1 378770471 11809005 813538..813855 1 NC_016804.1 50S ribosomal protein L24 813855 rplX 11809005 rplX Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L24 YP_005170204.1 813538 D 717522 CDS YP_005170205.1 378770472 11809006 813855..814418 1 NC_016804.1 Differs from Rv0716, Mb0737 by 1aa S134N in Mycobacterium bovis BCG Tokyo; 50S ribosomal protein L5 814418 rplE 11809006 rplE Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L5 YP_005170205.1 813855 D 717522 CDS YP_005170206.1 378770473 11809007 814423..814608 1 NC_016804.1 30S ribosomal protein S14 814608 rpsN1 11809007 rpsN1 Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S14 YP_005170206.1 814423 D 717522 CDS YP_005170207.1 378770474 11809008 814718..815116 1 NC_016804.1 30S ribosomal protein S8 815116 rpsH 11809008 rpsH Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S8 YP_005170207.1 814718 D 717522 CDS YP_005170208.1 378770475 11809009 815140..815679 1 NC_016804.1 50S ribosomal protein L6 815679 rplF 11809009 rplF Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L6 YP_005170208.1 815140 D 717522 CDS YP_005170209.1 378770476 11809010 815682..816050 1 NC_016804.1 50S ribosomal protein L18 816050 rplR 11809010 rplR Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L18 YP_005170209.1 815682 D 717522 CDS YP_005170210.1 378770477 11809011 816070..816732 1 NC_016804.1 30S ribosomal protein S5 816732 rpsE 11809011 rpsE Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S5 YP_005170210.1 816070 D 717522 CDS YP_005170211.1 378770478 11809012 816735..816932 1 NC_016804.1 50S ribosomal protein L30 816932 rpmD 11809012 rpmD Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L30 YP_005170211.1 816735 D 717522 CDS YP_005170212.1 378770479 11809013 816932..817372 1 NC_016804.1 Differs from Rv0723 by 1aa T16I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 50S ribosomal protein L15 817372 rplO 11809013 rplO Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L15 YP_005170212.1 816932 D 717522 CDS YP_005170213.1 378770480 11809014 817405..819276 1 NC_016804.1 Endopeptidase IV; putative protease IV 819276 sppA 11809014 sppA Mycobacterium bovis BCG str. Mexico putative protease IV YP_005170213.1 817405 D 717522 CDS YP_005170214.1 378770481 11809015 complement(819281..820186) 1 NC_016804.1 hypothetical protein 820186 11809015 BCGMEX_0746c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170214.1 819281 R 717522 CDS YP_005170215.1 378770482 11809016 complement(820279..821382) 1 NC_016804.1 hypothetical protein 821382 11809016 BCGMEX_0747c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170215.1 820279 R 717522 CDS YP_005170216.1 378770483 11809017 complement(821585..822241) 1 NC_016804.1 L-fuculose phosphate aldolase 822241 fucA 11809017 fucA Mycobacterium bovis BCG str. Mexico L-fuculose phosphate aldolase YP_005170216.1 821585 R 717522 CDS YP_005170217.1 378770484 11809018 complement(822238..823218) 1 NC_016804.1 Differs from Rv0728c by 1aa H242R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; D-3-phosphoglycerate dehydrogenase 823218 serA2 11809018 serA2 Mycobacterium bovis BCG str. Mexico D-3-phosphoglycerate dehydrogenase YP_005170217.1 822238 R 717522 CDS YP_005170218.1 378770485 11809019 823249..824595 1 NC_016804.1 Differs from Rv0729 by 2aa P134L and S439 in Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; putative D-xylulose kinase 824595 xylB 11809019 xylB Mycobacterium bovis BCG str. Mexico putative D-xylulose kinase YP_005170218.1 823249 D 717522 CDS YP_005170219.1 378770486 11809020 824608..825336 1 NC_016804.1 hypothetical protein 825336 11809020 BCGMEX_0751 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170219.1 824608 D 717522 CDS YP_005170220.1 378770487 11809021 complement(825425..826381) 1 NC_016804.1 hypothetical protein 826381 11809021 BCGMEX_0752c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170220.1 825425 R 717522 CDS YP_005170221.1 378770488 11809022 826542..827867 1 NC_016804.1 preprotein translocase subunit secY 827867 secY 11809022 secY Mycobacterium bovis BCG str. Mexico preprotein translocase subunit secY YP_005170221.1 826542 D 717522 CDS YP_005170222.1 378770489 11809023 827864..828409 1 NC_016804.1 adenylate kinase 828409 adk 11809023 adk Mycobacterium bovis BCG str. Mexico adenylate kinase YP_005170222.1 827864 D 717522 CDS YP_005170223.1 378770490 11809024 828412..829212 1 NC_016804.1 methionine aminopeptidase 829212 mapA 11809024 mapA Mycobacterium bovis BCG str. Mexico methionine aminopeptidase YP_005170223.1 828412 D 717522 CDS YP_005170224.1 378770491 11809025 829285..829818 1 NC_016804.1 RNA polymerase sigma factor SigL 829818 sigL 11809025 sigL Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor SigL YP_005170224.1 829285 D 717522 CDS YP_005170225.1 378770492 11809026 829882..830634 1 NC_016804.1 hypothetical protein 830634 11809026 BCGMEX_0757 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170225.1 829882 D 717522 CDS YP_005170226.1 378770493 11809027 830949..831446 1 NC_016804.1 MarR family transcriptional regulator 831446 11809027 BCGMEX_0758 Mycobacterium bovis BCG str. Mexico MarR family transcriptional regulator YP_005170226.1 830949 D 717522 CDS YP_005170227.1 378770494 11809028 831804..832352 1 NC_016804.1 hypothetical protein 832352 11809028 BCGMEX_0759 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170227.1 831804 D 717522 CDS YP_005170228.1 378770495 11809029 832557..833405 1 NC_016804.1 hypothetical protein 833405 11809029 BCGMEX_0760 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170228.1 832557 D 717522 CDS YP_005170229.1 378770496 11809030 833520..834047 1 NC_016804.1 hypothetical protein 834047 11809030 BCGMEX_0761 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170229.1 833520 D 717522 CDS YP_005170230.1 378770497 11809031 834278..834592 1 NC_016804.1 transposase 834592 11809031 BCGMEX_0762 Mycobacterium bovis BCG str. Mexico transposase YP_005170230.1 834278 D 717522 CDS YP_005170231.1 378770498 11809032 834734..835252 1 NC_016804.1 PE PGRS family protein 835252 PE_PGRS8 11809032 PE_PGRS8 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005170231.1 834734 D 717522 CDS YP_005170232.1 378770499 11809033 complement(835630..836187) 1 NC_016804.1 hypothetical protein 836187 11809033 BCGMEX_0764c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170232.1 835630 R 717522 CDS YP_005170233.1 378770500 11809034 complement(836184..836690) 1 NC_016804.1 transcriptional regulator 836690 11809034 BCGMEX_0765c Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005170233.1 836184 R 717522 CDS YP_005170234.1 378770501 11809035 836898..837425 1 NC_016804.1 hypothetical protein 837425 11809035 BCGMEX_0766 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170234.1 836898 D 717522 CDS YP_005170235.1 378770502 11809036 837445..839838 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, two 48 bp deletions, and a 138 bp insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (797 aa versus 783 aa). Differs from Mb0767 by 1aa S597N in BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 839838 PE_PGRS9 11809036 PE_PGRS9 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170235.1 837445 D 717522 CDS YP_005170236.1 378770503 11809037 840237..842918 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, insertions of 168 bp and 105 bp, a 11 bp for 71 bp substitution, and a 9 bp deletion, leads to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (909 aa and 893 aa versus 801 aa). In addition, in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 48 bp deletion compared to Mycobacterium bovis and Mycobacterium tuberculosis strain H37Rv occurs; PE-PGRS family protein 842918 PE_PGRS10 11809037 PE_PGRS10 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170236.1 840237 D 717522 CDS YP_005170237.1 378770504 11809038 843009..843266 1 NC_016804.1 hypothetical protein 843266 11809038 BCGMEX_0769 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170237.1 843009 D 717522 CDS YP_005170238.1 378770505 11809039 843290..843718 1 NC_016804.1 hypothetical protein 843718 11809039 BCGMEX_0770 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170238.1 843290 D 717522 CDS YP_005170239.1 378770506 11809040 complement(843799..843936) 1 NC_016804.1 hypothetical protein 843936 11809040 BCGMEX_0771c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170239.1 843799 R 717522 CDS YP_005170240.1 378770507 11809041 844095..844340 1 NC_016804.1 hypothetical protein 844340 11809041 BCGMEX_0772 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170240.1 844095 D 717522 CDS YP_005170241.1 378770508 11809042 complement(844409..845293) 1 NC_016804.1 putative 3-hydroxyisobutyrate dehydrogenase 845293 mmsB 11809042 mmsB Mycobacterium bovis BCG str. Mexico putative 3-hydroxyisobutyrate dehydrogenase YP_005170241.1 844409 R 717522 CDS YP_005170242.1 378770509 11809043 complement(845304..846476) 1 NC_016804.1 Differs from Rv0752c by 2aa A69V and V186I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyl-CoA dehydrogenase 846476 fadE9 11809043 fadE9 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005170242.1 845304 R 717522 CDS YP_005170243.1 378770510 11809044 complement(846483..848015) 1 NC_016804.1 Differs from Mb0775c by 1aa V442G in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; methylmalonate-semialdehyde dehydrogenase 848015 mmsA 11809044 mmsA Mycobacterium bovis BCG str. Mexico methylmalonate-semialdehyde dehydrogenase YP_005170243.1 846483 R 717522 CDS YP_005170244.1 378770511 11809045 848230..849975 1 NC_016804.1 PE PGRS family protein 849975 PE_PGRS11 11809045 PE_PGRS11 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005170244.1 848230 D 717522 CDS YP_005170245.1 378770512 11809046 complement(850165..852102) 1 NC_016804.1 Differs from Rv0755c by 1aa K545R in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 852102 PPE12 11809046 PPE12 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170245.1 850165 R 717522 CDS YP_005170246.1 378770513 11809047 complement(852404..852589) 1 NC_016804.1 putative transposase 852589 11809047 BCGMEX_0778c Mycobacterium bovis BCG str. Mexico putative transposase YP_005170246.1 852404 R 717522 CDS YP_005170247.1 378770514 11809049 complement(852803..853528) 1 NC_016804.1 hypothetical protein 853528 11809049 BCGMEX_0779c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170247.1 852803 R 717522 CDS YP_005170248.1 378770515 11809050 853670..854413 1 NC_016804.1 putative two component system response transcriptional positive regulator 854413 phoP 11809050 phoP Mycobacterium bovis BCG str. Mexico putative two component system response transcriptional positive regulator YP_005170248.1 853670 D 717522 CDS YP_005170249.1 378770516 11809051 854458..855915 1 NC_016804.1 Differs from Rv0755c by 2aa I71G, L172P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative two component system response sensor kinase membrane associated 855915 phoR 11809051 phoR Mycobacterium bovis BCG str. Mexico putative two component system response sensor kinase membrane associated YP_005170249.1 854458 D 717522 CDS YP_005170250.1 378770517 11809052 complement(855887..856219) 1 NC_016804.1 hypothetical protein 856219 11809052 BCGMEX_0782c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170250.1 855887 R 717522 CDS YP_005170251.1 378770518 11809053 complement(856328..856747) 1 NC_016804.1 hypothetical protein 856747 11809053 BCGMEX_0783c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170251.1 856328 R 717522 CDS YP_005170252.1 378770519 11809054 complement(856760..857887) 1 NC_016804.1 putative zinc-containing alcohol dehydrogenase NAD dependent 857887 adhB 11809054 adhB Mycobacterium bovis BCG str. Mexico putative zinc-containing alcohol dehydrogenase NAD dependent YP_005170252.1 856760 R 717522 CDS YP_005170253.1 378770520 11809055 complement(857986..858531) 1 NC_016804.1 hypothetical protein 858531 11809055 BCGMEX_0785c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170253.1 857986 R 717522 CDS YP_005170254.1 378770521 11809056 complement(858534..858740) 1 NC_016804.1 putative ferredoxin 858740 11809056 BCGMEX_0786c Mycobacterium bovis BCG str. Mexico putative ferredoxin YP_005170254.1 858534 R 717522 CDS YP_005170255.1 378770522 11809057 complement(858743..860098) 1 NC_016804.1 cytochrome P450 51 860098 cyp51 11809057 cyp51 Mycobacterium bovis BCG str. Mexico cytochrome P450 51 YP_005170255.1 858743 R 717522 CDS YP_005170256.1 378770523 11809058 complement(860098..860925) 1 NC_016804.1 short-chain dehydrogenase 860925 11809058 BCGMEX_0788c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005170256.1 860098 R 717522 CDS YP_005170257.1 378770524 11809059 complement(860507..862132) 1 NC_016804.1 putative cytochrome P450 123 862132 cyp123 11809059 cyp123 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 123 YP_005170257.1 860507 R 717522 CDS YP_005170258.1 378770525 11809060 complement(862129..862770) 1 NC_016804.1 hypothetical protein 862770 11809060 BCGMEX_0790c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170258.1 862129 R 717522 CDS YP_005170259.1 378770526 11809061 862972..864441 1 NC_016804.1 putative aldehyde dehydrogenase NAD dependent 864441 aldA 11809061 aldA Mycobacterium bovis BCG str. Mexico putative aldehyde dehydrogenase NAD dependent YP_005170259.1 862972 D 717522 CDS YP_005170260.1 378770527 11809062 864472..865218 1 NC_016804.1 Differs from Rv0769 by 1aa V55A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; short-chain dehydrogenase 865218 11809062 BCGMEX_0792 Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005170260.1 864472 D 717522 CDS YP_005170261.1 378770528 11809063 865316..866203 1 NC_016804.1 Differs from Mb0793 by 1aa V126G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative dehydrogenase/reductase 866203 11809063 BCGMEX_0793 Mycobacterium bovis BCG str. Mexico putative dehydrogenase/reductase YP_005170261.1 865316 D 717522 CDS YP_005170262.1 378770529 11809064 866200..866634 1 NC_016804.1 4-carboxymuconolactone decarboxylase 866634 11809064 BCGMEX_0794 Mycobacterium bovis BCG str. Mexico 4-carboxymuconolactone decarboxylase YP_005170262.1 866200 D 717522 CDS YP_005170263.1 378770530 11809065 866646..867914 1 NC_016804.1 phosphoribosylamine--glycine ligase 867914 purD 11809065 purD Mycobacterium bovis BCG str. Mexico phosphoribosylamine--glycine ligase YP_005170263.1 866646 D 717522 CDS YP_005170264.1 378770531 11809066 complement(867911..869449) 1 NC_016804.1 Gamma-glutamyltranspeptidase; putative cephalosporin acylase 869449 ggtA 11809066 ggtA Mycobacterium bovis BCG str. Mexico putative cephalosporin acylase YP_005170264.1 867911 R 717522 CDS YP_005170265.1 378770532 11809067 complement(869500..870411) 1 NC_016804.1 Differs from Rv0774c by 1aa A219S and from Mb0797c by 1aa D142A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 870411 11809067 BCGMEX_0797c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170265.1 869500 R 717522 CDS YP_005170266.1 378770533 11809068 870467..871090 1 NC_016804.1 hypothetical protein 871090 11809068 BCGMEX_0798 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170266.1 870467 D 717522 CDS YP_005170267.1 378770534 11809069 complement(871044..871823) 1 NC_016804.1 hypothetical protein 871823 11809069 BCGMEX_0799c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170267.1 871044 R 717522 CDS YP_005170268.1 378770535 11809070 872068..873486 1 NC_016804.1 Differs from Rv0777 by 1aa P422T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative adenylosuccinate lyase 873486 purB 11809070 purB Mycobacterium bovis BCG str. Mexico putative adenylosuccinate lyase YP_005170268.1 872068 D 717522 CDS YP_005170269.1 378770536 11809071 873491..874735 1 NC_016804.1 putative cytochrome P450 126 874735 cyp126 11809071 cyp126 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 126 YP_005170269.1 873491 D 717522 CDS YP_005170270.1 378770537 11809072 complement(874732..875352) 1 NC_016804.1 transmembrane protein 875352 11809072 BCGMEX_0802c Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170270.1 874732 R 717522 CDS YP_005170271.1 378770538 11809073 875403..876296 1 NC_016804.1 phosphoribosylaminoimidazole-succinocarboxamide synthase 876296 purC 11809073 purC Mycobacterium bovis BCG str. Mexico phosphoribosylaminoimidazole-succinocarboxamide synthase YP_005170271.1 875403 D 717522 CDS YP_005170272.1 378770539 11809074 876293..878452 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, ptrB is split into 2 genes, ptrBa and ptrBb, due to a frameshift. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 2 bp insertion leads to a single product; oligopeptidase B; putative protease II 878452 ptrB 11809074 ptrB Mycobacterium bovis BCG str. Mexico putative protease II YP_005170272.1 876293 D 717522 CDS YP_005170273.1 378770540 11809075 complement(878880..880502) 1 NC_016804.1 putative multidrug resistance integral membrane efflux protein 880502 emrB 11809075 emrB Mycobacterium bovis BCG str. Mexico putative multidrug resistance integral membrane efflux protein YP_005170273.1 878880 R 717522 CDS YP_005170274.1 378770541 11809076 880700..881386 1 NC_016804.1 hypothetical protein 881386 11809076 BCGMEX_0806 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170274.1 880700 D 717522 CDS YP_005170275.1 378770542 11809077 881402..881977 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0785 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion, splits Mb0807 into 2 parts, Mb0807 and Mb0808; hypothetical protein 881977 11809077 BCGMEX_0807 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170275.1 881402 D 717522 CDS YP_005170276.1 378770543 11809078 881995..883101 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0785 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion, splits Mb0807 into 2 parts, Mb0807 and Mb0808; hypothetical protein 883101 11809078 BCGMEX_0808 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170276.1 881995 D 717522 CDS YP_005170277.1 378770544 11809079 complement(883136..883525) 1 NC_016804.1 hypothetical protein 883525 11809079 BCGMEX_0809c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170277.1 883136 R 717522 CDS YP_005170278.1 378770545 11809080 883520..884479 1 NC_016804.1 Differs from Rv0787 by 1aa H269Y in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; hypothetical protein 884479 11809080 BCGMEX_0810 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170278.1 883520 D 717522 CDS YP_005170279.1 378770546 11809081 884585..884824 1 NC_016804.1 phosphoribosylformylglycinamidine synthase subunit PurS 884824 11809081 BCGMEX_0811 Mycobacterium bovis BCG str. Mexico phosphoribosylformylglycinamidine synthase subunit PurS YP_005170279.1 884585 D 717522 CDS YP_005170280.1 378770547 11809082 884821..885495 1 NC_016804.1 phosphoribosylformylglycinamidine synthase subunit I 885495 purQ 11809082 purQ Mycobacterium bovis BCG str. Mexico phosphoribosylformylglycinamidine synthase subunit I YP_005170280.1 884821 D 717522 CDS YP_005170281.1 378770548 11809083 complement(885512..886111) 1 NC_016804.1 hypothetical protein 886111 11809083 BCGMEX_0813c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170281.1 885512 R 717522 CDS YP_005170282.1 378770549 11809084 complement(886133..886861) 1 NC_016804.1 hypothetical protein 886861 11809084 BCGMEX_0814c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170282.1 886133 R 717522 CDS YP_005170283.1 378770550 11809085 complement(886858..887901) 1 NC_016804.1 hypothetical protein 887901 11809085 BCGMEX_0815c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170283.1 886858 R 717522 CDS YP_005170284.1 378770551 11809086 complement(887898..888707) 1 NC_016804.1 putative transcriptional regulatory protein, probably GntR-family 888707 11809086 BCGMEX_0816c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, probably GntR-family YP_005170284.1 887898 R 717522 CDS YP_005170285.1 378770552 11809087 888780..889085 1 NC_016804.1 hypothetical protein 889085 11809087 BCGMEX_0817 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170285.1 888780 D 717522 CDS YP_005170286.1 378770553 11809088 complement(889198..889809) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0794c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico, a frameshift due to a single base deletion splits Rv0794c into 2 parts; putative oxidoreductase 889809 11809088 BCGMEX_0818c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170286.1 889198 R 717522 CDS YP_005170287.1 378770554 11809089 complement(889797..890696) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv0794c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico, a frameshift due to a single base deletion splits Rv0794c into 2 parts; putative oxidoreductase 890696 11809089 BCGMEX_0819c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170287.1 889797 R 717522 CDS YP_005170288.1 378770555 11809090 891089..892183 1 NC_016804.1 putative transposase for insertion sequence element IS1547 892183 11809090 BCGMEX_0820 Mycobacterium bovis BCG str. Mexico putative transposase for insertion sequence element IS1547 YP_005170288.1 891089 D 717522 CDS YP_005170289.1 378770556 11809091 complement(892173..892970) 1 NC_016804.1 29 kDa antigen 892970 cfp29 11809091 cfp29 Mycobacterium bovis BCG str. Mexico 29 kDa antigen YP_005170289.1 892173 R 717522 CDS YP_005170290.1 378770557 11809092 complement(892967..893974) 1 NC_016804.1 hypothetical protein 893974 11809092 BCGMEX_0822c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170290.1 892967 R 717522 CDS YP_005170291.1 378770558 11809093 894019..895320 1 NC_016804.1 Differs from Rv0800 by 1aa R139L in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; putative M18 family aminopeptidase 2 895320 pepC 11809093 pepC Mycobacterium bovis BCG str. Mexico putative M18 family aminopeptidase 2 YP_005170291.1 894019 D 717522 CDS YP_005170292.1 378770559 11809094 895332..895679 1 NC_016804.1 hypothetical protein 895679 11809094 BCGMEX_0824 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170292.1 895332 D 717522 CDS YP_005170293.1 378770560 11809095 complement(895673..896329) 1 NC_016804.1 hypothetical protein 896329 11809095 BCGMEX_0825c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170293.1 895673 R 717522 CDS YP_005170294.1 378770561 11809096 896521..898785 1 NC_016804.1 phosphoribosylformylglycinamidine synthase II 898785 purL 11809096 purL Mycobacterium bovis BCG str. Mexico phosphoribosylformylglycinamidine synthase II YP_005170294.1 896521 D 717522 CDS YP_005170295.1 378770562 11809097 898782..899411 1 NC_016804.1 hypothetical protein 899411 11809097 BCGMEX_0827 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170295.1 898782 D 717522 CDS YP_005170296.1 378770563 11809098 899532..900488 1 NC_016804.1 hypothetical protein 900488 11809098 BCGMEX_0828 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170296.1 899532 D 717522 CDS YP_005170297.1 378770564 11809099 complement(900433..902031) 1 NC_016804.1 putative UDP-glucose-4-epimerase 902031 cpsY 11809099 cpsY Mycobacterium bovis BCG str. Mexico putative UDP-glucose-4-epimerase YP_005170297.1 900433 R 717522 CDS YP_005170298.1 378770565 11809100 902336..902725 1 NC_016804.1 hypothetical protein 902725 11809100 BCGMEX_0830 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170298.1 902336 D 717522 CDS YP_005170299.1 378770566 11809101 902812..904395 1 NC_016804.1 amidophosphoribosyltransferase 904395 purF 11809101 purF Mycobacterium bovis BCG str. Mexico amidophosphoribosyltransferase YP_005170299.1 902812 D 717522 CDS YP_005170300.1 378770567 11809102 904426..905520 1 NC_016804.1 phosphoribosylformylglycinamidine cyclo-ligase 905520 purM 11809102 purM Mycobacterium bovis BCG str. Mexico phosphoribosylformylglycinamidine cyclo-ligase YP_005170300.1 904426 D 717522 CDS YP_005170301.1 378770568 11809103 complement(905606..905788) 1 NC_016804.1 hypothetical protein 905788 11809103 BCGMEX_0833c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170301.1 905606 R 717522 CDS YP_005170302.1 378770569 11809104 complement(905935..907041) 1 NC_016804.1 hypothetical protein 907041 11809104 BCGMEX_0834c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170302.1 905935 R 717522 CDS YP_005170303.1 378770570 11809105 907106..907993 1 NC_016804.1 Differs from Rv0812 by 1aa M145I in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative aminotransferasa 907993 11809105 BCGMEX_0835 Mycobacterium bovis BCG str. Mexico putative aminotransferasa YP_005170303.1 907106 D 717522 CDS YP_005170304.1 378770571 11809106 complement(908039..908719) 1 NC_016804.1 similar to BCG_0865c; hypothetical protein 908719 11809106 BCGMEX_0836c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170304.1 908039 R 717522 CDS YP_005170305.1 378770572 11809107 complement(908882..909184) 1 NC_016804.1 hypothetical protein 909184 sseC2 11809107 sseC2 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170305.1 908882 R 717522 CDS YP_005170306.1 378770573 11809108 complement(909186..910019) 1 NC_016804.1 Rhodanese-like protein; thiosulfate sulfurtransferase 910019 cysA2 11809108 cysA2 Mycobacterium bovis BCG str. Mexico thiosulfate sulfurtransferase YP_005170306.1 909186 R 717522 CDS YP_005170307.1 378770574 11809109 complement(910312..910734) 1 NC_016804.1 putative thioredoxin 910734 thiX 11809109 thiX Mycobacterium bovis BCG str. Mexico putative thioredoxin YP_005170307.1 910312 R 717522 CDS YP_005170308.1 378770575 11809110 complement(910731..911543) 1 NC_016804.1 hypothetical protein 911543 11809110 BCGMEX_0840c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170308.1 910731 R 717522 CDS YP_005170309.1 378770576 11809111 911673..912440 1 NC_016804.1 Differs from Rv0818 by 1aa P97L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; transcriptional regulatory protein 912440 11809111 BCGMEX_0841 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein YP_005170309.1 911673 D 717522 CDS YP_005170310.1 378770577 11809112 912437..913384 1 NC_016804.1 hypothetical protein 913384 11809112 BCGMEX_0842 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170310.1 912437 D 717522 CDS YP_005170311.1 378770578 11809113 913427..913939 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv and Mycobacterium bovis phoT exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion , splits phoT into two parts phoTa and phoTb. Differs from Rv0820 by 1aa L35F in BCG Pasteur, BCG Tokyo and BCG Mexico; putative phosphate-transport ATP-binding protein ABC transporter 913939 phoTa 11809113 phoTa Mycobacterium bovis BCG str. Mexico putative phosphate-transport ATP-binding protein ABC transporter YP_005170311.1 913427 D 717522 CDS YP_005170312.1 378770579 11809115 complement(914258..914899) 1 NC_016804.1 putative phosphate-transport system transcriptional regulatory protein 914899 phoY2 11809115 phoY2 Mycobacterium bovis BCG str. Mexico putative phosphate-transport system transcriptional regulatory protein YP_005170312.1 914258 R 717522 CDS YP_005170313.1 378770580 11809116 complement(914957..917011) 1 NC_016804.1 Differs from Rv0822c by 1aa P89H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; hypothetical protein 917011 11809116 BCGMEX_0846c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170313.1 914957 R 717522 CDS YP_005170314.1 378770581 11809117 complement(917177..918346) 1 NC_016804.1 Differs from Rv0823c by 2aa C130G and L330F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; transcriptional regulator 918346 11809117 BCGMEX_0847c Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005170314.1 917177 R 717522 CDS YP_005170315.1 378770582 11809118 complement(918434..919450) 1 NC_016804.1 putative acyl-[acyl-carrier protein] desaturase DESA1 (Acyl-[ACP] desaturase) 919450 desA1 11809118 desA1 Mycobacterium bovis BCG str. Mexico putative acyl-[acyl-carrier protein] desaturase DESA1 (Acyl-[ACP] desaturase) YP_005170315.1 918434 R 717522 CDS YP_005170316.1 378770583 11809119 complement(919612..920253) 1 NC_016804.1 hypothetical protein 920253 11809119 BCGMEX_0849c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170316.1 919612 R 717522 CDS YP_005170317.1 378770584 11809120 920334..921389 1 NC_016804.1 Differs from Rv0826 by 1aa Q294R and Mb0849 by 1aaE97G in BCG Pasteur BCG Tokyo and BCG Mexico; hypothetical protein 921389 11809120 BCGMEX_0850 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170317.1 920334 D 717522 CDS YP_005170318.1 378770585 11809121 complement(921441..921833) 1 NC_016804.1 putative transcriptional regulatory protein 921833 11809121 BCGMEX_0851c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170318.1 921441 R 717522 CDS YP_005170319.1 378770586 11809122 complement(921891..922313) 1 NC_016804.1 putative deaminase 922313 11809122 BCGMEX_0852c Mycobacterium bovis BCG str. Mexico putative deaminase YP_005170319.1 921891 R 717522 CDS YP_005170320.1 378770587 11809123 922275..922565 1 NC_016804.1 Differs from Rv0829 by 1aa G80A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 922565 11809123 BCGMEX_0853 Mycobacterium bovis BCG str. Mexico putative transposase YP_005170320.1 922275 D 717522 CDS YP_005170321.1 378770588 11809124 922670..923575 1 NC_016804.1 putative S-adenosyl-L-methionine-dependent methyltransferase 923575 11809124 BCGMEX_0854 Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005170321.1 922670 D 717522 CDS YP_005170322.1 378770589 11809125 complement(923594..924409) 1 NC_016804.1 hypothetical protein 924409 11809125 BCGMEX_0855c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170322.1 923594 R 717522 CDS YP_005170323.1 378770590 11809130 925651..928383 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, PE-PGRS13 exist as a single gene. In Mycobacterium tuberculosis and Mycobacterium bovis, it is splitted in 2 genes PE-PGRS12 and PE-PGRS13; PE-PGRS family protein 928383 PE_PGRS13 11809130 PE_PGRS13 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170323.1 925651 D 717522 CDS YP_005170324.1 378770591 11809131 complement(928610..931258) 1 NC_016804.1 In Mycobacterium bovis, deletions of 143 bp and 9 bp, leads to a shorter product compared to the homolog in Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico (831 aa versus 882 aa); putative S-adenosyl-L-methionine-dependent methyltransferase 931258 PE_PGRS14 11809131 PE_PGRS14 Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005170324.1 928610 R 717522 CDS YP_005170325.1 378770592 11809132 931726..932370 1 NC_016804.1 Differs from Rv0835 by 1aa G162D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; putative lipoprotein 932370 lpqQ 11809132 lpqQ Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170325.1 931726 D 717522 CDS YP_005170326.1 378770593 11809133 complement(932983..933705) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico, a single base transition leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (240 aa versus 217 aa); hypothetical protein 933705 11809133 BCGMEX_0859c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170326.1 932983 R 717522 CDS YP_005170327.1 378770594 11809134 complement(933776..934804) 1 NC_016804.1 hypothetical protein 934804 11809134 BCGMEX_0860c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170327.1 933776 R 717522 CDS YP_005170328.1 378770595 11809135 935493..936275 1 NC_016804.1 In Mycobacterium bovis, a 6bp insertion leads to a slightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (258 aa versus 256 aa). In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 12bp insertion (compared to its homolog in Mycobacterium tuberculosis strain H37Rv) and a 6bp insertion (compared to its homolog in Mycobacterium bovis) leads to an even longer product (260 aa); putative lipoprotein 936275 lpqR 11809135 lpqR Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170328.1 935493 D 717522 CDS YP_005170329.1 378770596 11809136 936362..937174 1 NC_016804.1 hypothetical protein 937174 11809136 BCGMEX_0862 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170329.1 936362 D 717522 CDS YP_005170330.1 378770597 11809137 complement(937242..938102) 1 NC_016804.1 putative proline iminopeptidase PIP 938102 pip 11809137 pip Mycobacterium bovis BCG str. Mexico putative proline iminopeptidase PIP YP_005170330.1 937242 R 717522 CDS YP_005170331.1 378770598 11809138 938378..938620 1 NC_016804.1 Differs from Rv0841 by 1aa F29V in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 938620 11809138 BCGMEX_0864 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170331.1 938378 D 717522 CDS YP_005170332.1 378770599 11809139 938897..940189 1 NC_016804.1 putative integral membrane protein 940189 11809139 BCGMEX_0865 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170332.1 938897 D 717522 CDS YP_005170333.1 378770600 11809140 940173..941177 1 NC_016804.1 Differs from Rv0843 by 1aa G191D and from Mb0866 by 1aa A309D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative dehydrogenase 941177 11809140 BCGMEX_0866 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005170333.1 940173 D 717522 CDS YP_005170334.1 378770601 11809141 complement(941241..941891) 1 NC_016804.1 Differs from Mb0867c by 1aa A73P in BCG Pasteur, BCG Tokyo and BCG Mexico; putative nitrate/nitrite response transcriptional regulatory protein 941891 narL 11809141 narL Mycobacterium bovis BCG str. Mexico putative nitrate/nitrite response transcriptional regulatory protein YP_005170334.1 941241 R 717522 CDS YP_005170335.1 378770602 11809142 941975..943252 1 NC_016804.1 Differs from Rv0845 by 1aa E219A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; putative two component sensor kinase 943252 11809142 BCGMEX_0868 Mycobacterium bovis BCG str. Mexico putative two component sensor kinase YP_005170335.1 941975 D 717522 CDS YP_005170336.1 378770603 11809143 complement(943465..944979) 1 NC_016804.1 Differs from Mb0869c by 1aa Y411H in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; putative oxidase 944979 11809143 BCGMEX_0869c Mycobacterium bovis BCG str. Mexico putative oxidase YP_005170336.1 943465 R 717522 CDS YP_005170337.1 378770604 11809144 945128..945520 1 NC_016804.1 Differs from Rv0847 by 1aa V128A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico; putative lipoprotein 945520 lpqS 11809144 lpqS Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170337.1 945128 D 717522 CDS YP_005170338.1 378770605 11809145 945723..946841 1 NC_016804.1 Differs from Rv0848 by 1aa S93G, and from Mb0871 by 1aa V137G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative cysteine synthase A 946841 cysK2 11809145 cysK2 Mycobacterium bovis BCG str. Mexico putative cysteine synthase A YP_005170338.1 945723 D 717522 CDS YP_005170339.1 378770606 11809146 946841..948100 1 NC_016804.1 putative integral membrane transport protein 948100 11809146 BCGMEX_0872 Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005170339.1 946841 D 717522 CDS YP_005170340.1 378770607 11809147 948097..948429 1 NC_016804.1 putative transposase 948429 11809147 BCGMEX_0873 Mycobacterium bovis BCG str. Mexico putative transposase YP_005170340.1 948097 D 717522 CDS YP_005170341.1 378770608 11809148 complement(948426..949253) 1 NC_016804.1 Differs from Rv0851c by 1aa G59S and from Mb0874c by 1aa V84F in BCG Pasteur, BCG Tokyo and BCG Mexico; short-chain dehydrogenase 949253 11809148 BCGMEX_0874c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005170341.1 948426 R 717522 CDS YP_005170342.1 378770609 11809149 949344..950180 1 NC_016804.1 putative fatty-acid-CoA ligase 950180 fadD16 11809149 fadD16 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005170342.1 949344 D 717522 CDS YP_005170343.1 378770610 11809150 complement(950221..951903) 1 NC_016804.1 putative pyruvate decarboxylase 951903 pdc 11809150 pdc Mycobacterium bovis BCG str. Mexico putative pyruvate decarboxylase YP_005170343.1 950221 R 717522 CDS YP_005170344.1 378770611 11809151 951968..952411 1 NC_016804.1 hypothetical protein 952411 11809151 BCGMEX_0877 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170344.1 951968 D 717522 CDS YP_005170345.1 378770612 11809152 952417..953496 1 NC_016804.1 putative fatty-acid-CoA racemase 953496 far 11809152 far Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA racemase YP_005170345.1 952417 D 717522 CDS YP_005170346.1 378770613 11809153 953609..954013 1 NC_016804.1 hypothetical protein 954013 11809153 BCGMEX_0879 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170346.1 953609 D 717522 CDS YP_005170347.1 378770614 11809154 954041..954514 1 NC_016804.1 hypothetical protein 954514 11809154 BCGMEX_0880 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170347.1 954041 D 717522 CDS YP_005170348.1 378770615 11809155 complement(954511..955704) 1 NC_016804.1 putative aminotransferase 955704 11809155 BCGMEX_0881c Mycobacterium bovis BCG str. Mexico putative aminotransferase YP_005170348.1 954511 R 717522 CDS YP_005170349.1 378770616 11809156 955861..957072 1 NC_016804.1 Differs from Rv0859 by 1aa G150S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA acetyltransferase 957072 fadA 11809156 fadA Mycobacterium bovis BCG str. Mexico acyl-CoA acetyltransferase YP_005170349.1 955861 D 717522 CDS YP_005170350.1 378770617 11809157 957077..959239 1 NC_016804.1 Differs from Rv0860 by 1aa T701A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative fatty oxidation protein 959239 fadB 11809157 fadB Mycobacterium bovis BCG str. Mexico putative fatty oxidation protein YP_005170350.1 957077 D 717522 CDS YP_005170351.1 378770618 11809158 complement(959307..960935) 1 NC_016804.1 Differs from Rv0861c by 1aa A258V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative DNA helicase 960935 11809158 BCGMEX_0884c Mycobacterium bovis BCG str. Mexico putative DNA helicase YP_005170351.1 959307 R 717522 CDS YP_005170352.1 378770619 11809159 complement(961073..963343) 1 NC_016804.1 Differs from Rv0862c by 2aa F224L and S749L, and from Mb0885c by 1aa F224L in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 963343 11809159 BCGMEX_0885c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170352.1 961073 R 717522 CDS YP_005170353.1 378770620 11809160 963330..963611 1 NC_016804.1 hypothetical protein 963611 11809160 BCGMEX_0886 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170353.1 963330 D 717522 CDS YP_005170354.1 378770621 11809161 963695..964123 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion leads to a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; molybdenum cofactor biosynthesis protein C 964123 moaC2 11809161 moaC2 Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein C YP_005170354.1 963695 D 717522 CDS YP_005170355.1 378770622 11809162 964120..964602 1 NC_016804.1 putative molybdopterin biosynthesis mog protein 964602 mog 11809162 mog Mycobacterium bovis BCG str. Mexico putative molybdopterin biosynthesis mog protein YP_005170355.1 964120 D 717522 CDS YP_005170356.1 378770623 11809163 964599..965024 1 NC_016804.1 Molybdopterin converting factor subunit 2; molybdenum cofactor biosynthesis protein E 965024 moaE2 11809163 moaE2 Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein E YP_005170356.1 964599 D 717522 CDS YP_005170357.1 378770624 11809164 complement(965042..966265) 1 NC_016804.1 In Mycobacterium bovis, a 240 bp deletion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico(327 aa versus 407 aa). Differs from Rv0867c by 1aa E235D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative resuscitation-promoting factor 966265 rpfA 11809164 rpfA Mycobacterium bovis BCG str. Mexico putative resuscitation-promoting factor YP_005170357.1 965042 R 717522 CDS YP_005170358.1 378770625 11809165 complement(966713..966991) 1 NC_016804.1 molybdenum cofactor biosynthesis protein D2 966991 moaD2 11809165 moaD2 Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein D2 YP_005170358.1 966713 R 717522 CDS YP_005170359.1 378770626 11809166 complement(966995..968077) 1 NC_016804.1 molybdenum cofactor biosynthesis protein A 968077 moaA 11809166 moaA Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein A YP_005170359.1 966995 R 717522 CDS YP_005170360.1 378770627 11809167 complement(968074..968463) 1 NC_016804.1 integral membrane protein 968463 11809167 BCGMEX_0893c Mycobacterium bovis BCG str. Mexico integral membrane protein YP_005170360.1 968074 R 717522 CDS YP_005170361.1 378770628 11809168 968628..969035 1 NC_016804.1 putative cold shock-like protein B 969035 cspB 11809168 cspB Mycobacterium bovis BCG str. Mexico putative cold shock-like protein B YP_005170361.1 968628 D 717522 CDS YP_005170362.1 378770629 11809169 complement(969154..970983) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 9 bp in-frame insertion (compared to Mycobacterium tuberculosis strain H37Rv), leads to a lightly longer product (609 aa versus 606 aa). In Mycobacterium bovis, an additional 3 bp in-frame deletion (compared to Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico) leads to a product of 608 aa; PE PGRS family protein 970983 PE_PGRS15 11809169 PE_PGRS15 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005170362.1 969154 R 717522 CDS YP_005170363.1 378770630 11809170 971244..973196 1 NC_016804.1 putative acyl-CoA dehydrogenase 973196 fadE10 11809170 fadE10 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005170363.1 971244 D 717522 CDS YP_005170364.1 378770631 11809171 complement(973285..974445) 1 NC_016804.1 hypothetical protein 974445 11809171 BCGMEX_0897c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170364.1 973285 R 717522 CDS YP_005170365.1 378770632 11809172 complement(974545..975033) 1 NC_016804.1 hypothetical protein 975033 11809172 BCGMEX_0898c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170365.1 974545 R 717522 CDS YP_005170366.1 378770633 11809173 complement(975030..976676) 1 NC_016804.1 Differs from Mb0900c by 1aa D26G in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 976676 11809173 BCGMEX_0899c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170366.1 975030 R 717522 CDS YP_005170367.1 378770634 11809174 976814..977602 1 NC_016804.1 hypothetical protein 977602 11809174 BCGMEX_0900 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170367.1 976814 D 717522 CDS YP_005170368.1 378770635 11809175 complement(977611..978939) 1 NC_016804.1 In Mycobacterium bovis, Mycobaterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base deletion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (438 aa versus 443 aa). Differs from Rv0878c and Mb0902c by 1aa K436Q in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 978939 PPE13 11809175 PPE13 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170368.1 977611 R 717522 CDS YP_005170369.1 378770636 11809176 complement(979217..979492) 1 NC_016804.1 transmembrane protein 979492 11809176 BCGMEX_0902c Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170369.1 979217 R 717522 CDS YP_005170370.1 378770637 11809177 979670..980101 1 NC_016804.1 MarR-family transcriptional regulator 980101 11809177 BCGMEX_0903 Mycobacterium bovis BCG str. Mexico MarR-family transcriptional regulator YP_005170370.1 979670 D 717522 CDS YP_005170371.1 378770638 11809178 980098..980964 1 NC_016804.1 putative rRNA methylase 980964 11809178 BCGMEX_0904 Mycobacterium bovis BCG str. Mexico putative rRNA methylase YP_005170371.1 980098 D 717522 CDS YP_005170372.1 378770639 11809179 980961..981245 1 NC_016804.1 transmembrane protein 981245 11809179 BCGMEX_0905 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170372.1 980961 D 717522 CDS YP_005170373.1 378770640 11809180 complement(981242..982003) 1 NC_016804.1 hypothetical protein 982003 11809180 BCGMEX_0906c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170373.1 981242 R 717522 CDS YP_005170374.1 378770641 11809181 complement(982160..983290) 1 NC_016804.1 phosphoserine aminotransferase 983290 serC 11809181 serC Mycobacterium bovis BCG str. Mexico phosphoserine aminotransferase YP_005170374.1 982160 R 717522 CDS YP_005170375.1 378770642 11809182 983498..984520 1 NC_016804.1 hypothetical protein 984520 11809182 BCGMEX_0908 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170375.1 983498 D 717522 CDS YP_005170376.1 378770643 11809183 984539..986266 1 NC_016804.1 putative NADPH:adrenodoxin oxidoreductase 986266 fprB 11809183 fprB Mycobacterium bovis BCG str. Mexico putative NADPH:adrenodoxin oxidoreductase YP_005170376.1 984539 D 717522 CDS YP_005170377.1 378770644 11809184 complement(986249..986707) 1 NC_016804.1 hypothetical protein 986707 11809184 BCGMEX_0910c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170377.1 986249 R 717522 CDS YP_005170378.1 378770645 11809185 987969..989441 1 NC_016804.1 hypothetical protein 989441 11809185 BCGMEX_0911 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170378.1 987969 D 717522 CDS YP_005170379.1 378770646 11809186 complement(989476..990597) 1 NC_016804.1 Citrate synthase II 990597 citA 11809186 citA Mycobacterium bovis BCG str. Mexico Citrate synthase II YP_005170379.1 989476 R 717522 CDS YP_005170380.1 378770647 11809187 complement(990684..993332) 1 NC_016804.1 Differs from Rv0890c by 1aa A866P in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; probably LuxR-family; putative transcriptional regulatory protein 993332 11809187 BCGMEX_0913c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170380.1 990684 R 717522 CDS YP_005170381.1 378770648 11809188 complement(993334..994191) 1 NC_016804.1 Differs from Rv0891c by 1aa G37V in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 994191 11809188 BCGMEX_0914c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170381.1 993334 R 717522 CDS YP_005170382.1 378770649 11809189 994589..996076 1 NC_016804.1 putative monooxygenase 996076 11809189 BCGMEX_0915 Mycobacterium bovis BCG str. Mexico putative monooxygenase YP_005170382.1 994589 D 717522 CDS YP_005170383.1 378770650 11809190 complement(996054..997031) 1 NC_016804.1 putative S-adenosyl-L-methionine-dependent methyltransferase 997031 11809190 BCGMEX_0916c Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005170383.1 996054 R 717522 CDS YP_005170384.1 378770651 11809191 997260..998441 1 NC_016804.1 putative transcriptional regulatory protein, LuxR-family 998441 11809191 BCGMEX_0917 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, LuxR-family YP_005170384.1 997260 D 717522 CDS YP_005170385.1 378770652 11809192 998518..1000035 1 NC_016804.1 hypothetical protein 1000035 11809192 BCGMEX_0918 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170385.1 998518 D 717522 CDS YP_005170386.1 378770653 11809193 1000225..1001520 1 NC_016804.1 Differs from Rv0896 by 1aa, A421T in Mycobacterium bovis, BCG Pasteur,BCG Tokyo and BCG Mexico; Type II Citrate synthase 1001520 gltA 11809193 gltA Mycobacterium bovis BCG str. Mexico Type II Citrate synthase YP_005170386.1 1000225 D 717522 CDS YP_005170387.1 378770654 11809194 complement(1001561..1003168) 1 NC_016804.1 putative oxidoreductase 1003168 11809194 BCGMEX_0920c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170387.1 1001561 R 717522 CDS YP_005170388.1 378770655 11809195 complement(1003194..1003457) 1 NC_016804.1 hypothetical protein 1003457 11809195 BCGMEX_0921c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170388.1 1003194 R 717522 CDS YP_005170389.1 378770656 11809196 1003565..1004545 1 NC_016804.1 putative outer membrane protein 1004545 ompA 11809196 ompA Mycobacterium bovis BCG str. Mexico putative outer membrane protein YP_005170389.1 1003565 D 717522 CDS YP_005170390.1 378770657 11809197 1004558..1004710 1 NC_016804.1 hypothetical protein 1004710 11809197 BCGMEX_0923 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170390.1 1004558 D 717522 CDS YP_005170391.1 378770658 11809198 1004710..1005237 1 NC_016804.1 exported or membrane protein 1005237 11809198 BCGMEX_0924 Mycobacterium bovis BCG str. Mexico exported or membrane protein YP_005170391.1 1004710 D 717522 CDS YP_005170392.1 378770659 11809199 complement(1005254..1006594) 1 NC_016804.1 Two component sensor histidine kinase prrB 1006594 prrB 11809199 prrB Mycobacterium bovis BCG str. Mexico Two component sensor histidine kinase prrB YP_005170392.1 1005254 R 717522 CDS YP_005170393.1 378770660 11809200 complement(1006605..1007315) 1 NC_016804.1 Two component response transcriptional regulatory protein 1007315 prrA 11809200 prrA Mycobacterium bovis BCG str. Mexico Two component response transcriptional regulatory protein YP_005170393.1 1006605 R 717522 CDS YP_005170394.1 378770661 11809201 complement(1007446..1008933) 1 NC_016804.1 putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 1008933 accD3 11809201 accD3 Mycobacterium bovis BCG str. Mexico putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta YP_005170394.1 1007446 R 717522 CDS YP_005170395.1 378770662 11809202 1008960..1009691 1 NC_016804.1 Enoyl-CoA hydratase 1009691 echA6 11809202 echA6 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170395.1 1008960 D 717522 CDS YP_005170396.1 378770663 11809203 1009697..1010815 1 NC_016804.1 hypothetical protein 1010815 11809203 BCGMEX_0929 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170396.1 1009697 D 717522 CDS YP_005170397.1 378770664 11809204 1010908..1012488 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base insertion leads to a shorter product with a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Differs from Rv0907 by 1aa, L322P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1012488 11809204 BCGMEX_0930 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170397.1 1010908 D 717522 CDS YP_005170398.1 378770665 11809205 1012485..1014878 1 NC_016804.1 putative metal cation transporter ATPase P-type 1014878 ctpE 11809205 ctpE Mycobacterium bovis BCG str. Mexico putative metal cation transporter ATPase P-type YP_005170398.1 1012485 D 717522 CDS YP_005170399.1 378770666 11809206 1015435..1015614 1 NC_016804.1 Differs from Rv0909 by 1aa, Q45H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1015614 11809206 BCGMEX_0932 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170399.1 1015435 D 717522 CDS YP_005170400.1 378770667 11809207 1015620..1016054 1 NC_016804.1 hypothetical protein 1016054 11809207 BCGMEX_0933 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170400.1 1015620 D 717522 CDS YP_005170401.1 378770668 11809208 1016152..1016925 1 NC_016804.1 hypothetical protein 1016925 11809208 BCGMEX_0934 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170401.1 1016152 D 717522 CDS YP_005170402.1 378770669 11809209 1016990..1017439 1 NC_016804.1 transmembrane protein 1017439 11809209 BCGMEX_0935 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170402.1 1016990 D 717522 CDS YP_005170403.1 378770670 11809210 complement(1017971..1019479) 1 NC_016804.1 putative dioxygenase 1019479 11809210 BCGMEX_0936c Mycobacterium bovis BCG str. Mexico putative dioxygenase YP_005170403.1 1017971 R 717522 CDS YP_005170404.1 378770671 11809211 complement(1019481..1020719) 1 NC_016804.1 Lipid carrier protein or keto acyl-CoA thiolase 1020719 11809211 BCGMEX_0937c Mycobacterium bovis BCG str. Mexico Lipid carrier protein or keto acyl-CoA thiolase YP_005170404.1 1019481 R 717522 CDS YP_005170405.1 378770672 11809212 complement(1020812..1022083) 1 NC_016804.1 PPE family protein 1022083 PPE14 11809212 PPE14 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170405.1 1020812 R 717522 CDS YP_005170406.1 378770673 11809213 complement(1022098..1022397) 1 NC_016804.1 PE family protein 1022397 PE7 11809213 PE7 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170406.1 1022098 R 717522 CDS YP_005170407.1 378770674 11809214 1022841..1024622 1 NC_016804.1 putative glycine betaine transport integral membrane protein 1024622 betP 11809214 betP Mycobacterium bovis BCG str. Mexico putative glycine betaine transport integral membrane protein YP_005170407.1 1022841 D 717522 CDS YP_005170408.1 378770675 11809215 1024965..1025441 1 NC_016804.1 Differs from Rv0918 by 1aa, G46S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1025441 11809215 BCGMEX_0941 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170408.1 1024965 D 717522 CDS YP_005170409.1 378770676 11809216 1025438..1025938 1 NC_016804.1 hypothetical protein 1025938 11809216 BCGMEX_0942 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170409.1 1025438 D 717522 CDS YP_005170410.1 378770677 11809218 complement(1026251..1027570) 1 NC_016804.1 Differs from Rv0920c by 1aa, E249D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 1027570 11809218 BCGMEX_0943c Mycobacterium bovis BCG str. Mexico putative transposase YP_005170410.1 1026251 R 717522 CDS YP_005170411.1 378770678 11809219 1027858..1028439 1 NC_016804.1 putative resolvase 1028439 11809219 BCGMEX_0944 Mycobacterium bovis BCG str. Mexico putative resolvase YP_005170411.1 1027858 D 717522 CDS YP_005170412.1 378770679 11809220 1028439..1030091 1 NC_016804.1 putative transposase 1030091 11809220 BCGMEX_0945 Mycobacterium bovis BCG str. Mexico putative transposase YP_005170412.1 1028439 D 717522 CDS YP_005170413.1 378770680 11809221 complement(1030267..1031331) 1 NC_016804.1 hypothetical protein 1031331 11809221 BCGMEX_0946c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170413.1 1030267 R 717522 CDS YP_005170414.1 378770681 11809222 complement(1031332..1032618) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, Rv0924c and Rv0925c exist as 2 genes. In Mycobacterium bovis, a single base deletion leads to a single product, Mb0948c. Differs from Rv0924c by 1aa, A216P in BCG Pasteur, BCG Tokyo and BCG Mexico; Manganese transport protein 1032618 mntH 11809222 mntH Mycobacterium bovis BCG str. Mexico Manganese transport protein YP_005170414.1 1031332 R 717522 CDS YP_005170415.1 378770682 11809223 complement(1032650..1033387) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, Rv0924c and Rv0925c exist as 2 genes. In Mycobacterium bovis, a single base deletion leads to a single product, Mb0948c; Nramp; Mramp; divalent cation-transport integral membrane protein 1033387 11809223 BCGMEX_0948c Mycobacterium bovis BCG str. Mexico divalent cation-transport integral membrane protein YP_005170415.1 1032650 R 717522 CDS YP_005170416.1 378770683 11809224 complement(1033464..1034540) 1 NC_016804.1 hypothetical protein 1034540 11809224 BCGMEX_0949c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170416.1 1033464 R 717522 CDS YP_005170417.1 378770684 11809225 complement(1034594..1035385) 1 NC_016804.1 short-chain dehydrogenase 1035385 11809225 BCGMEX_0950c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005170417.1 1034594 R 717522 CDS YP_005170418.1 378770685 11809226 1035657..1036769 1 NC_016804.1 periplasmic phosphate-binding lipoprotein 1036769 pstS3 11809226 pstS3 Mycobacterium bovis BCG str. Mexico periplasmic phosphate-binding lipoprotein YP_005170418.1 1035657 D 717522 CDS YP_005170419.1 378770686 11809227 1036782..1037756 1 NC_016804.1 phosphate ABC transporter permease 1037756 pstC2 11809227 pstC2 Mycobacterium bovis BCG str. Mexico phosphate ABC transporter permease YP_005170419.1 1036782 D 717522 CDS YP_005170420.1 378770687 11809228 1037753..1038667 1 NC_016804.1 Differs from Rv0930 by 1aa, T5M in Mycobacterium CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phosphate-transport integral membrane ABC transporter 1038667 pstA1 11809228 pstA1 Mycobacterium bovis BCG str. Mexico phosphate-transport integral membrane ABC transporter YP_005170420.1 1037753 D 717522 CDS YP_005170421.1 378770688 11809229 complement(1038674..1039561) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, pknD exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion splits pknD into 2 parts,pknDa and pknDb; Serine/threonine-protein kinase 1039561 pknDb 11809229 pknDb Mycobacterium bovis BCG str. Mexico Serine/threonine-protein kinase YP_005170421.1 1038674 R 717522 CDS YP_005170422.1 378770689 11809230 complement(1039794..1040669) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, pknD exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion splits pknD into 2 parts,pknDa and pknDb; Transmembrane serine/threonine-protein kinase D 1040669 pknDa 11809230 pknDa Mycobacterium bovis BCG str. Mexico Transmembrane serine/threonine-protein kinase D YP_005170422.1 1039794 R 717522 CDS YP_005170423.1 378770690 11809231 complement(1040691..1041803) 1 NC_016804.1 Differs from Rv0932c by 1aa, A115S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; periplasmic phosphate-binding protein 1041803 pstS2 11809231 pstS2 Mycobacterium bovis BCG str. Mexico periplasmic phosphate-binding protein YP_005170423.1 1040691 R 717522 CDS YP_005170424.1 378770691 11809232 1042019..1042234 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, pstB exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base insertion splits pstB into 2 parts, pstBa and pstBb; phosphate-transport protein ABC transporter 1042234 pstBa 11809232 pstBa Mycobacterium bovis BCG str. Mexico phosphate-transport protein ABC transporter YP_005170424.1 1042019 D 717522 CDS YP_005170425.1 378770692 11809233 1042209..1042850 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, pstB exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base insertion splits pstB into 2 parts, pstBa and pstBb; phosphate-transport protein ABC transporter 1042850 pstBb 11809233 pstBb Mycobacterium bovis BCG str. Mexico phosphate-transport protein ABC transporter YP_005170425.1 1042209 D 717522 CDS YP_005170426.1 378770693 11809234 1042871..1043995 1 NC_016804.1 Differs from Rv0934 by 1aa, A352V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; periplasmic phosphate-binding lipoprotein 1043995 pstS1 11809234 pstS1 Mycobacterium bovis BCG str. Mexico periplasmic phosphate-binding lipoprotein YP_005170426.1 1042871 D 717522 CDS YP_005170427.1 378770694 11809235 1044055..1045071 1 NC_016804.1 phosphate-transport integral membrane ABC transporter 1045071 pstC1 11809235 pstC1 Mycobacterium bovis BCG str. Mexico phosphate-transport integral membrane ABC transporter YP_005170427.1 1044055 D 717522 CDS YP_005170428.1 378770695 11809236 1045073..1045978 1 NC_016804.1 phosphate-transport integral membrane ABC transporter 1045978 pstA2 11809236 pstA2 Mycobacterium bovis BCG str. Mexico phosphate-transport integral membrane ABC transporter YP_005170428.1 1045073 D 717522 CDS YP_005170429.1 378770696 11809237 complement(1045955..1046776) 1 NC_016804.1 hypothetical protein 1046776 11809237 BCGMEX_0962c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170429.1 1045955 R 717522 CDS YP_005170430.1 378770697 11809238 1046892..1049171 1 NC_016804.1 putative ATP dependent DNA ligase 1049171 11809238 BCGMEX_0963 Mycobacterium bovis BCG str. Mexico putative ATP dependent DNA ligase YP_005170430.1 1046892 D 717522 CDS YP_005170431.1 378770698 11809239 1049168..1051102 1 NC_016804.1 cyclase/dehydrase; putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 1051102 11809239 BCGMEX_0964 Mycobacterium bovis BCG str. Mexico putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase YP_005170431.1 1049168 D 717522 CDS YP_005170432.1 378770699 11809240 complement(1051349..1052215) 1 NC_016804.1 putative oxidoreductase 1052215 11809240 BCGMEX_0965c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170432.1 1051349 R 717522 CDS YP_005170433.1 378770700 11809241 complement(1052300..1053073) 1 NC_016804.1 hypothetical protein 1053073 11809241 BCGMEX_0966c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170433.1 1052300 R 717522 CDS YP_005170434.1 378770701 11809242 1053116..1053394 1 NC_016804.1 hypothetical protein 1053394 11809242 BCGMEX_0967 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170434.1 1053116 D 717522 CDS YP_005170435.1 378770702 11809243 complement(1053452..1054492) 1 NC_016804.1 putative monooxygenase 1054492 11809243 BCGMEX_0968c Mycobacterium bovis BCG str. Mexico putative monooxygenase YP_005170435.1 1053452 R 717522 CDS YP_005170436.1 378770703 11809244 1054521..1054997 1 NC_016804.1 Formamidopyrimidine-DNA glycosylase 1054997 11809244 BCGMEX_0969 Mycobacterium bovis BCG str. Mexico Formamidopyrimidine-DNA glycosylase YP_005170436.1 1054521 D 717522 CDS YP_005170437.1 378770704 11809245 1055003..1055764 1 NC_016804.1 Differs from Rv0945 by 1aa, G180R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative short-chain type dehydrogenase/reductase 1055764 11809245 BCGMEX_0970 Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005170437.1 1055003 D 717522 CDS YP_005170438.1 378770705 11809246 complement(1055780..1057441) 1 NC_016804.1 putative Glucose-6-phosphate isomerase 1057441 pgi 11809246 pgi Mycobacterium bovis BCG str. Mexico putative Glucose-6-phosphate isomerase YP_005170438.1 1055780 R 717522 CDS YP_005170439.1 378770706 11809247 complement(1058056..1058286) 1 NC_016804.1 putative mycolyl transferase 1058286 11809247 BCGMEX_0972c Mycobacterium bovis BCG str. Mexico putative mycolyl transferase YP_005170439.1 1058056 R 717522 CDS YP_005170440.1 378770707 11809248 complement(1058402..1058719) 1 NC_016804.1 hypothetical protein 1058719 11809248 BCGMEX_0973c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170440.1 1058402 R 717522 CDS YP_005170441.1 378770708 11809249 1059016..1061331 1 NC_016804.1 putative ATP dependent DNA helicase 1061331 uvrD1 11809249 uvrD1 Mycobacterium bovis BCG str. Mexico putative ATP dependent DNA helicase YP_005170441.1 1059016 D 717522 CDS YP_005170442.1 378770709 11809250 complement(1061412..1062410) 1 NC_016804.1 hypothetical protein 1062410 11809250 BCGMEX_0975c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170442.1 1061412 R 717522 CDS YP_005170443.1 378770710 11809251 1062720..1063883 1 NC_016804.1 Differs from Rv0951 by 1aa, A261V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; succinyl-CoA synthetase subunit beta 1063883 sucC 11809251 sucC Mycobacterium bovis BCG str. Mexico succinyl-CoA synthetase subunit beta YP_005170443.1 1062720 D 717522 CDS YP_005170444.1 378770711 11809252 1063896..1064807 1 NC_016804.1 Differs from Rv0952 by 1aa, K209R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; succinyl-CoA synthetase subunit alpha 1064807 sucD 11809252 sucD Mycobacterium bovis BCG str. Mexico succinyl-CoA synthetase subunit alpha YP_005170444.1 1063896 D 717522 CDS YP_005170445.1 378770712 11809253 complement(1064870..1065718) 1 NC_016804.1 Differs from Rv0953c and Mb0978c by 1aa, A50T in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 1065718 11809253 BCGMEX_0978c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170445.1 1064870 R 717522 CDS YP_005170446.1 378770713 11809254 1065883..1066794 1 NC_016804.1 transmembrane protein 1066794 11809254 BCGMEX_0979 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170446.1 1065883 D 717522 CDS YP_005170447.1 378770714 11809255 1066834..1068201 1 NC_016804.1 integral membrane protein 1068201 11809255 BCGMEX_0980 Mycobacterium bovis BCG str. Mexico integral membrane protein YP_005170447.1 1066834 D 717522 CDS YP_005170448.1 378770715 11809256 1068317..1068964 1 NC_016804.1 phosphoribosylglycinamide formyltransferase 1068964 purN 11809256 purN Mycobacterium bovis BCG str. Mexico phosphoribosylglycinamide formyltransferase YP_005170448.1 1068317 D 717522 CDS YP_005170449.1 378770716 11809257 1068961..1070532 1 NC_016804.1 IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase 1070532 purH 11809257 purH Mycobacterium bovis BCG str. Mexico phosphoribosylaminoimidazolecarboxamide formyltransferase YP_005170449.1 1068961 D 717522 CDS YP_005170450.1 378770717 11809258 1070639..1072018 1 NC_016804.1 Differs from Rv0958 by 1aa, P274S in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative magnesium chelatase 1072018 11809258 BCGMEX_0983 Mycobacterium bovis BCG str. Mexico putative magnesium chelatase YP_005170450.1 1070639 D 717522 CDS YP_005170451.1 378770718 11809259 1072011..1074029 1 NC_016804.1 hypothetical protein 1074029 11809259 BCGMEX_0984 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170451.1 1072011 D 717522 CDS YP_005170452.1 378770719 11809260 1074083..1074304 1 NC_016804.1 hypothetical protein 1074304 11809260 BCGMEX_0985 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170452.1 1074083 D 717522 CDS YP_005170453.1 378770720 11809261 1074301..1074684 1 NC_016804.1 hypothetical protein 1074684 11809261 BCGMEX_0986 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170453.1 1074301 D 717522 CDS YP_005170454.1 378770721 11809262 1074830..1075177 1 NC_016804.1 putative integral membrane protein 1075177 11809262 BCGMEX_0987 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170454.1 1074830 D 717522 CDS YP_005170455.1 378770722 11809263 complement(1075196..1075870) 1 NC_016804.1 Differs from Rv0962c by 1aa, L186P in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 1075870 lprP 11809263 lprP Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170455.1 1075196 R 717522 CDS YP_005170456.1 378770723 11809264 complement(1076053..1076853) 1 NC_016804.1 Differs from Rv0963c and Mb0988c by 1aa, S258G in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1076853 11809264 BCGMEX_0989c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170456.1 1076053 R 717522 CDS YP_005170457.1 378770724 11809265 complement(1076952..1077434) 1 NC_016804.1 Differs from Rv0964c by 1aa, T124P in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1077434 11809265 BCGMEX_0990c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170457.1 1076952 R 717522 CDS YP_005170458.1 378770725 11809266 complement(1077534..1077953) 1 NC_016804.1 Differs from Rv0965c by 1aa, H94R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1077953 11809266 BCGMEX_0991c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170458.1 1077534 R 717522 CDS YP_005170459.1 378770726 11809267 complement(1077989..1078591) 1 NC_016804.1 Differs from Rv0966c by 2aa, A175V, G186W in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1078591 11809267 BCGMEX_0992c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170459.1 1077989 R 717522 CDS YP_005170460.1 378770727 11809268 1078730..1079089 1 NC_016804.1 hypothetical protein 1079089 11809268 BCGMEX_0993 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170460.1 1078730 D 717522 CDS YP_005170461.1 378770728 11809269 1079146..1079442 1 NC_016804.1 hypothetical protein 1079442 11809269 BCGMEX_0994 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170461.1 1079146 D 717522 CDS YP_005170462.1 378770729 11809270 1079498..1081810 1 NC_016804.1 Differs from Rv0969 by 1aa, N484D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative metal cation transporter P-type atpase 1081810 11809270 BCGMEX_0995 Mycobacterium bovis BCG str. Mexico putative metal cation transporter P-type atpase YP_005170462.1 1079498 D 717522 CDS YP_005170463.1 378770730 11809271 1081807..1082439 1 NC_016804.1 putative integral membrane protein 1082439 11809271 BCGMEX_0996 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170463.1 1081807 D 717522 CDS YP_005170464.1 378770731 11809272 complement(1082530..1083339) 1 NC_016804.1 Enoyl-CoA hydratase 1083339 echA7 11809272 echA7 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170464.1 1082530 R 717522 CDS YP_005170465.1 378770732 11809273 complement(1083339..1084505) 1 NC_016804.1 Differs from Rv0972c by 1aa, H236Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyl-CoA dehydrogenase 1084505 fadE12 11809273 fadE12 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005170465.1 1083339 R 717522 CDS YP_005170466.1 378770733 11809274 complement(1084502..1086505) 1 NC_016804.1 Differs from Rv0973c by 1aa, F220I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acetyl-/propionyl-coenzyme A carboxylase alpha chain subunit alpha 1086505 accA2 11809274 accA2 Mycobacterium bovis BCG str. Mexico putative acetyl-/propionyl-coenzyme A carboxylase alpha chain subunit alpha YP_005170466.1 1084502 R 717522 CDS YP_005170467.1 378770734 11809275 complement(1086511..1088100) 1 NC_016804.1 Differs from Rv0974c by 1aa, K51N in Mycobacteium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acetyl-/propionyl-coa carboxylase subunit beta 1088100 accD2 11809275 accD2 Mycobacterium bovis BCG str. Mexico putative acetyl-/propionyl-coa carboxylase subunit beta YP_005170467.1 1086511 R 717522 CDS YP_005170468.1 378770735 11809276 complement(1088103..1089251) 1 NC_016804.1 In Mycobacterium bovis, a frameshift due to a single base deletion leads to a shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG pasteur, BCG Tokyo and BCG Mexico; acyl-CoA dehydrogenase FadE13 1089251 fadE13 11809276 fadE13 Mycobacterium bovis BCG str. Mexico acyl-CoA dehydrogenase FadE13 YP_005170468.1 1088103 R 717522 CDS YP_005170469.1 378770736 11809277 complement(1089248..1090930) 1 NC_016804.1 hypothetical protein 1090930 11809277 BCGMEX_1002c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170469.1 1089248 R 717522 CDS YP_005170470.1 378770737 11809278 1091129..1093900 1 NC_016804.1 PE-PGRS family protein 1093900 PE_PGRS16 11809278 PE_PGRS16 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170470.1 1091129 D 717522 CDS YP_005170471.1 378770738 11809279 complement(1094117..1095124) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterim bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 115 bp to 127 bp substitution leads to as lightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (335 aa versus 331aa); PE PGRS family protein 1095124 PE_PGRS17 11809279 PE_PGRS17 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005170471.1 1094117 R 717522 CDS YP_005170472.1 378770739 11809280 complement(1095438..1095632) 1 NC_016804.1 hypothetical protein 1095632 11809280 BCGMEX_1005c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170472.1 1095438 R 717522 CDS YP_005170473.1 378770740 11809281 1095654..1095827 1 NC_016804.1 50S ribosomal protein L32 1095827 rpmF 11809281 rpmF Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L32 YP_005170473.1 1095654 D 717522 CDS YP_005170474.1 378770741 11809282 complement(1095846..1097219) 1 NC_016804.1 Differs from Rv0980c by 1aa, Q43H, and from Mb1006c by 1aa, A270T in Mycobacteium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 1097219 PE_PGRS18 11809282 PE_PGRS18 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170474.1 1095846 R 717522 CDS YP_005170475.1 378770742 11809283 1097584..1098276 1 NC_016804.1 Differs from Rv0981 by 1aa, S70G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Response regulator 1098276 mprA 11809283 mprA Mycobacterium bovis BCG str. Mexico Response regulator YP_005170475.1 1097584 D 717522 CDS YP_005170476.1 378770743 11809284 1098276..1099790 1 NC_016804.1 Differs from Rv0982 by 1aa, H339L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative two component sensor kinase 1099790 mprB 11809284 mprB Mycobacterium bovis BCG str. Mexico putative two component sensor kinase YP_005170476.1 1098276 D 717522 CDS YP_005170477.1 378770744 11809285 1099834..1101228 1 NC_016804.1 Differs from Rv0983 by 1aa, P390L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico; putative serine protease 1101228 11809285 BCGMEX_1010 Mycobacterium bovis BCG str. Mexico putative serine protease YP_005170477.1 1099834 D 717522 CDS YP_005170478.1 378770745 11809286 1101228..1101773 1 NC_016804.1 putative pterin-4-alpha-carbinolamine dehydratase 1101773 moaB2 11809286 moaB2 Mycobacterium bovis BCG str. Mexico putative pterin-4-alpha-carbinolamine dehydratase YP_005170478.1 1101228 D 717522 CDS YP_005170479.1 378770746 11809287 complement(1101793..1102248) 1 NC_016804.1 Differs from Rv0985c and Mb1011c by 1aa, L145R in BCG Pasteur, BCG Tokyo and BCG Mexico; Large-conductance mechanosensitive channel 1102248 mscL 11809287 mscL Mycobacterium bovis BCG str. Mexico Large-conductance mechanosensitive channel YP_005170479.1 1101793 R 717522 CDS YP_005170480.1 378770747 11809288 1102571..1103317 1 NC_016804.1 Differs from Rv0986 by 1aa, L228V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico; putative adhesion component transport ATP-binding protein ABC transporter 1103317 11809288 BCGMEX_1013 Mycobacterium bovis BCG str. Mexico putative adhesion component transport ATP-binding protein ABC transporter YP_005170480.1 1102571 D 717522 CDS YP_005170481.1 378770748 11809289 1103310..1105877 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium tuberculosis strain H37Rv, Rv0987 exists as a single gene. In Mycobacterium bovis, a single base transition introduces a stop codon that splits Rv0987 in two parts, Mb1013 and Mb1014. Differs from Rv0987 by 1aa, V717F in BCG Pasteur, BCG Tokyo and BCG Mexico; putative adhesion component transport transmembrane protein ABC transporter 1105877 11809289 BCGMEX_1014 Mycobacterium bovis BCG str. Mexico putative adhesion component transport transmembrane protein ABC transporter YP_005170481.1 1103310 D 717522 CDS YP_005170482.1 378770749 11809290 1105884..1107044 1 NC_016804.1 Differs from Rv0988 by 2aa, I57V, D135Y in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1107044 11809290 BCGMEX_1015 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170482.1 1105884 D 717522 CDS YP_005170483.1 378770750 11809291 complement(1107173..1108150) 1 NC_016804.1 Differs from Rv0989c by 1aa, V321I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyprenyl-diphosphate synthase 1108150 grcC2 11809291 grcC2 Mycobacterium bovis BCG str. Mexico putative polyprenyl-diphosphate synthase YP_005170483.1 1107173 R 717522 CDS YP_005170484.1 378770751 11809292 complement(1108211..1108867) 1 NC_016804.1 Differs from Rv0990c by 1aa, A54S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1108867 11809292 BCGMEX_1017c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170484.1 1108211 R 717522 CDS YP_005170485.1 378770752 11809293 complement(1108940..1109272) 1 NC_016804.1 hypothetical protein 1109272 11809293 BCGMEX_1018c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170485.1 1108940 R 717522 CDS YP_005170486.1 378770753 11809294 complement(1109346..1109939) 1 NC_016804.1 Differs from Rv0992c by 2aa, I3M, S135G, and from Mb1019c by 1aa, S135G in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1109939 11809294 BCGMEX_1019c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170486.1 1109346 R 717522 CDS YP_005170487.1 378770754 11809295 1110040..1110960 1 NC_016804.1 Differs from Rv0993 by 1aa, R235Q in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative UTP--glucose-1-phosphate uridylyltransferase 1110960 galU 11809295 galU Mycobacterium bovis BCG str. Mexico putative UTP--glucose-1-phosphate uridylyltransferase YP_005170487.1 1110040 D 717522 CDS YP_005170488.1 378770755 11809296 1111037..1112317 1 NC_016804.1 Differs from Rv0994 by 1aa, G230C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative molybdopterin biosynthesis protein 1112317 moeA1 11809296 moeA1 Mycobacterium bovis BCG str. Mexico putative molybdopterin biosynthesis protein YP_005170488.1 1111037 D 717522 CDS YP_005170489.1 378770756 11809297 1112380..1112991 1 NC_016804.1 putative ribosomal-protein-S5p-alanine acetyltransferase 1112991 rimJ 11809297 rimJ Mycobacterium bovis BCG str. Mexico putative ribosomal-protein-S5p-alanine acetyltransferase YP_005170489.1 1112380 D 717522 CDS YP_005170490.1 378770757 11809298 1113152..1114228 1 NC_016804.1 Differs from Rv0996 by 1aa, D92G, and from Mb1023 by 1aa, D92G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 1114228 11809298 BCGMEX_1023 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170490.1 1113152 D 717522 CDS YP_005170491.1 378770758 11809300 1114402..1114632 1 NC_016804.1 hypothetical protein 1114632 11809300 BCGMEX_1024 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170491.1 1114402 D 717522 CDS YP_005170492.1 378770759 11809301 1114629..1114880 1 NC_016804.1 hypothetical protein 1114880 11809301 BCGMEX_1025 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170492.1 1114629 D 717522 CDS YP_005170493.1 378770760 11809302 1115061..1115492 1 NC_016804.1 hypothetical protein 1115492 11809302 BCGMEX_1026 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170493.1 1115061 D 717522 CDS YP_005170494.1 378770761 11809303 1115516..1116517 1 NC_016804.1 hypothetical protein 1116517 11809303 BCGMEX_1027 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170494.1 1115516 D 717522 CDS YP_005170495.1 378770762 11809304 1116535..1117293 1 NC_016804.1 hypothetical protein 1117293 11809304 BCGMEX_1028 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170495.1 1116535 D 717522 CDS YP_005170496.1 378770763 11809305 complement(1117299..1117916) 1 NC_016804.1 hypothetical protein 1117916 11809305 BCGMEX_1029c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170496.1 1117299 R 717522 CDS YP_005170497.1 378770764 11809306 1117953..1119161 1 NC_016804.1 Arginine deiminase 1119161 arcA 11809306 arcA Mycobacterium bovis BCG str. Mexico Arginine deiminase YP_005170497.1 1117953 D 717522 CDS YP_005170498.1 378770765 11809307 complement(1119196..1120707) 1 NC_016804.1 Differs from Rv1002c by 1aa, L115V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; hypothetical protein 1120707 11809307 BCGMEX_1031c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170498.1 1119196 R 717522 CDS YP_005170499.1 378770766 11809308 1120790..1121647 1 NC_016804.1 Tetrapyrrole (Corrin-Porphyrin) methylase family protein UPF0011 1121647 11809308 BCGMEX_1032 Mycobacterium bovis BCG str. Mexico Tetrapyrrole (Corrin-Porphyrin) methylase family protein UPF0011 YP_005170499.1 1120790 D 717522 CDS YP_005170500.1 378770767 11809309 complement(1121657..1122916) 1 NC_016804.1 hypothetical protein 1122916 11809309 BCGMEX_1033c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170500.1 1121657 R 717522 CDS YP_005170501.1 378770768 11809310 complement(1122990..1124426) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, as in Mycobacterium bovis, a single base transition leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (478 aa versus 458 aa); Para-aminobenzoate synthase component I 1124426 11809310 BCGMEX_1034c Mycobacterium bovis BCG str. Mexico Para-aminobenzoate synthase component I YP_005170501.1 1122990 R 717522 CDS YP_005170502.1 378770769 11809311 1124482..1126185 1 NC_016804.1 Differs from Rv1006 by 1aa, S535P, and from Mb1033 by 1aa, N25S in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1126185 11809311 BCGMEX_1035 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170502.1 1124482 D 717522 CDS YP_005170503.1 378770770 11809312 complement(1126212..1127771) 1 NC_016804.1 Differs from Rv1007c by 1aa, G39R in BCG Pasteur, BCG Tokyo and BCG Mexico; methionyl-tRNA synthetase 1127771 metS 11809312 metS Mycobacterium bovis BCG str. Mexico methionyl-tRNA synthetase YP_005170503.1 1126212 R 717522 CDS YP_005170504.1 378770771 11809313 1127857..1128651 1 NC_016804.1 Differs from Rv1008 by 1aa, N186T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; YjjV protein; deoxyribonuclease 1128651 tatD 11809313 tatD Mycobacterium bovis BCG str. Mexico deoxyribonuclease YP_005170504.1 1127857 D 717522 CDS YP_005170505.1 378770772 11809314 1128859..1129947 1 NC_016804.1 Differs from Rv1009 by 2aa, E282G, V357A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative resuscitation-promoting factor 1129947 rpfB 11809314 rpfB Mycobacterium bovis BCG str. Mexico putative resuscitation-promoting factor YP_005170505.1 1128859 D 717522 CDS YP_005170506.1 378770773 11809315 1129920..1130873 1 NC_016804.1 dimethyladenosine transferase 1130873 ksgA 11809315 ksgA Mycobacterium bovis BCG str. Mexico dimethyladenosine transferase YP_005170506.1 1129920 D 717522 CDS YP_005170507.1 378770774 11809316 1130959..1131879 1 NC_016804.1 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1131879 ispE 11809316 ispE Mycobacterium bovis BCG str. Mexico 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_005170507.1 1130959 D 717522 CDS YP_005170508.1 378770775 11809317 1131876..1132190 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1012 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base insertion leads to a different NH2 terminus. Differs from Rv1012 by 1aa, N65S; hypothetical protein 1132190 11809317 BCGMEX_1041 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170508.1 1131876 D 717522 CDS YP_005170509.1 378770776 11809318 1132394..1134028 1 NC_016804.1 putative polyketide synthase pks16 1134028 pks16 11809318 pks16 Mycobacterium bovis BCG str. Mexico putative polyketide synthase pks16 YP_005170509.1 1132394 D 717522 CDS YP_005170510.1 378770777 11809319 complement(1134102..1134677) 1 NC_016804.1 peptidyl-tRNA hydrolase 1134677 pth 11809319 pth Mycobacterium bovis BCG str. Mexico peptidyl-tRNA hydrolase YP_005170510.1 1134102 R 717522 CDS YP_005170511.1 378770778 11809320 complement(1134690..1135337) 1 NC_016804.1 50s ribosomal protein L25p 1135337 rplY 11809320 rplY Mycobacterium bovis BCG str. Mexico 50s ribosomal protein L25p YP_005170511.1 1134690 R 717522 CDS YP_005170512.1 378770779 11809321 complement(1135471..1136229) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a 5 bp deletion leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; putative lipoprotein 1136229 lpqT 11809321 lpqT Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170512.1 1135471 R 717522 CDS YP_005170513.1 378770780 11809322 complement(1136265..1137245) 1 NC_016804.1 Differs from Rv1017c by 1aa, H204R in Mycobacterium bovis BCG Mexico; ribose-phosphate pyrophosphokinase 1137245 prsA 11809322 prsA Mycobacterium bovis BCG str. Mexico ribose-phosphate pyrophosphokinase YP_005170513.1 1136265 R 717522 CDS YP_005170514.1 378770781 11809323 complement(1137337..1138824) 1 NC_016804.1 Differs from Mb1046c by 2aa, E160G, E246Q in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; bifunctional protein: UDP-N-acetylglucosamine pyrophosphorylase/ Glucosamine-1-phosphate N-acetyltransferase 1138824 glmU 11809323 glmU Mycobacterium bovis BCG str. Mexico bifunctional protein: UDP-N-acetylglucosamine pyrophosphorylase/ Glucosamine-1-phosphate N-acetyltransferase YP_005170514.1 1137337 R 717522 CDS YP_005170515.1 378770782 11809325 1139079..1139672 1 NC_016804.1 putative transcriptional regulatory protein, TetR-family 1139672 11809325 BCGMEX_1048 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR-family YP_005170515.1 1139079 D 717522 CDS YP_005170516.1 378770783 11809326 1139731..1143435 1 NC_016804.1 putative transcription-repair coupling factor 1143435 mfd 11809326 mfd Mycobacterium bovis BCG str. Mexico putative transcription-repair coupling factor YP_005170516.1 1139731 D 717522 CDS YP_005170517.1 378770784 11809327 1143435..1144412 1 NC_016804.1 Nucleoside triphosphate pyrophosphohydrolase 1144412 11809327 BCGMEX_1050 Mycobacterium bovis BCG str. Mexico Nucleoside triphosphate pyrophosphohydrolase YP_005170517.1 1143435 D 717522 CDS YP_005170518.1 378770785 11809328 1144500..1145231 1 NC_016804.1 Differs from Rv1022 by 1aa, P33T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 1145231 lpqU 11809328 lpqU Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170518.1 1144500 D 717522 CDS YP_005170519.1 378770786 11809329 1145328..1146617 1 NC_016804.1 enolase 1146617 eno 11809329 eno Mycobacterium bovis BCG str. Mexico enolase YP_005170519.1 1145328 D 717522 CDS YP_005170520.1 378770787 11809330 1146622..1147308 1 NC_016804.1 hypothetical protein 1147308 11809330 BCGMEX_1053 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170520.1 1146622 D 717522 CDS YP_005170521.1 378770788 11809331 1147325..1147792 1 NC_016804.1 hypothetical protein 1147792 11809331 BCGMEX_1054 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170521.1 1147325 D 717522 CDS YP_005170522.1 378770789 11809332 1147783..1148742 1 NC_016804.1 hypothetical protein 1148742 11809332 BCGMEX_1055 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170522.1 1147783 D 717522 CDS YP_005170523.1 378770790 11809333 complement(1149191..1149871) 1 NC_016804.1 putative transcriptional regulatory protein 1149871 kdpE 11809333 kdpE Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170523.1 1149191 R 717522 CDS YP_005170524.1 378770791 11809334 complement(1149868..1152450) 1 NC_016804.1 Differs from Rv1028c by 3aa, S83P, D295G, S368P, and from Mb1056c by 1aa, S83P in BCG Pasteur, BCG Tokyo and BCG Mexico; Sensor protein 1152450 kdpD 11809334 kdpD Mycobacterium bovis BCG str. Mexico Sensor protein YP_005170524.1 1149868 R 717522 CDS YP_005170525.1 378770792 11809335 1152684..1152776 1 NC_016804.1 hypothetical protein 1152776 kdpF 11809335 kdpF Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170525.1 1152684 D 717522 CDS YP_005170526.1 378770793 11809336 1152776..1154491 1 NC_016804.1 potassium-transporting ATPase subunit A 1154491 kdpA 11809336 kdpA Mycobacterium bovis BCG str. Mexico potassium-transporting ATPase subunit A YP_005170526.1 1152776 D 717522 CDS YP_005170527.1 378770794 11809337 1154488..1156617 1 NC_016804.1 potassium-transporting ATPase subunit B 1156617 kdpB 11809337 kdpB Mycobacterium bovis BCG str. Mexico potassium-transporting ATPase subunit B YP_005170527.1 1154488 D 717522 CDS YP_005170528.1 378770795 11809338 1156617..1157186 1 NC_016804.1 potassium-transporting ATPase subunit C 1157186 kdpC 11809338 kdpC Mycobacterium bovis BCG str. Mexico potassium-transporting ATPase subunit C YP_005170528.1 1156617 D 717522 CDS YP_005170529.1 378770796 11809339 complement(1157190..1158719) 1 NC_016804.1 two component sensor histidine kinase 1158719 trcS 11809339 trcS Mycobacterium bovis BCG str. Mexico two component sensor histidine kinase YP_005170529.1 1157190 R 717522 CDS YP_005170530.1 378770797 11809340 complement(1158727..1159500) 1 NC_016804.1 Two component transcriptional regulator 1159500 trcR 11809340 trcR Mycobacterium bovis BCG str. Mexico Two component transcriptional regulator YP_005170530.1 1158727 R 717522 CDS YP_005170531.1 378770798 11809341 complement(1159682..1160071) 1 NC_016804.1 putative transposase 1160071 11809341 BCGMEX_1064c Mycobacterium bovis BCG str. Mexico putative transposase YP_005170531.1 1159682 R 717522 CDS YP_005170532.1 378770799 11809342 complement(1160139..1160825) 1 NC_016804.1 putative transposase 1160825 11809342 BCGMEX_1065c Mycobacterium bovis BCG str. Mexico putative transposase YP_005170532.1 1160139 R 717522 CDS YP_005170533.1 378770800 11809343 complement(1160859..1161197) 1 NC_016804.1 putative IS1560 transposase 1161197 11809343 BCGMEX_1066c Mycobacterium bovis BCG str. Mexico putative IS1560 transposase YP_005170533.1 1160859 R 717522 CDS YP_005170534.1 378770801 11809344 complement(1161308..1161592) 1 NC_016804.1 Differs from Rv1037c by 1aa, L20Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ESAT-6 like protein 1 1161592 esxI 11809344 esxI Mycobacterium bovis BCG str. Mexico putative ESAT-6 like protein 1 YP_005170534.1 1161308 R 717522 CDS YP_005170535.1 378770802 11809345 complement(1161619..1161915) 1 NC_016804.1 putative EsaT-6 like protein 2 1161915 esxJ 11809345 esxJ Mycobacterium bovis BCG str. Mexico putative EsaT-6 like protein 2 YP_005170535.1 1161619 R 717522 CDS YP_005170536.1 378770803 11809346 complement(1162061..1163236) 1 NC_016804.1 Differs from Rv1039c and Mb1068c by 1aa, K175N in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 1163236 11809346 BCGMEX_1069c Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170536.1 1162061 R 717522 CDS YP_005170537.1 378770804 11809347 complement(1163313..1164140) 1 NC_016804.1 PE family protein 1164140 PE8 11809347 PE8 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170537.1 1163313 R 717522 CDS YP_005170538.1 378770805 11809349 complement(1165856..1166263) 1 NC_016804.1 Differs from Rv1042c by 1aa, E129G in Mycobacterium bovis and BCG Pasteur. Differs from Mb1070c by G129E in Mycobacterium tuberculosis and Mycobacterium bovis BCG Tokyo and BCG Mexico; putative IS like-2 transposase 1166263 11809349 BCGMEX_1072c Mycobacterium bovis BCG str. Mexico putative IS like-2 transposase YP_005170538.1 1165856 R 717522 CDS YP_005170539.1 378770806 11809350 complement(1166546..1167571) 1 NC_016804.1 Differs from Rv1043c by 1aa, T99A, and from Mb1072c by 1aa, G263C in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1167571 11809350 BCGMEX_1073c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170539.1 1166546 R 717522 CDS YP_005170540.1 378770807 11809351 1167818..1168441 1 NC_016804.1 hypothetical protein 1168441 11809351 BCGMEX_1074 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170540.1 1167818 D 717522 CDS YP_005170541.1 378770808 11809352 1168438..1169319 1 NC_016804.1 Differs from Mb1074 by 1aa, W104G in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; hypothetical protein 1169319 11809352 BCGMEX_1075 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170541.1 1168438 D 717522 CDS YP_005170542.1 378770809 11809353 complement(1169401..1169994) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 1bp insertion, compared to Mycobacterium tuberculosis strains H37Rv, leads to different C-terminus; hypothetical protein 1169994 11809353 BCGMEX_1076c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170542.1 1169401 R 717522 CDS YP_005170543.1 378770810 11809354 1170189..1171436 1 NC_016804.1 putative IS1081 transposase 1171436 11809354 BCGMEX_1077 Mycobacterium bovis BCG str. Mexico putative IS1081 transposase YP_005170543.1 1170189 D 717522 CDS YP_005170544.1 378770811 11809355 complement(1171804..1172919) 1 NC_016804.1 Differs from Rv1048c and Mb1077c by 2aa, A37D, T173A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1172919 11809355 BCGMEX_1078c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170544.1 1171804 R 717522 CDS YP_005170545.1 378770812 11809356 1173152..1173598 1 NC_016804.1 putative transcriptional repressor protein 1173598 11809356 BCGMEX_1079 Mycobacterium bovis BCG str. Mexico putative transcriptional repressor protein YP_005170545.1 1173152 D 717522 CDS YP_005170546.1 378770813 11809357 1173646..1174551 1 NC_016804.1 putative oxidoreductase 1174551 11809357 BCGMEX_1080 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170546.1 1173646 D 717522 CDS YP_005170547.1 378770814 11809358 complement(1174710..1175465) 1 NC_016804.1 hypothetical protein 1175465 11809358 BCGMEX_1081c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170547.1 1174710 R 717522 CDS YP_005170548.1 378770815 11809359 1176488..1176877 1 NC_016804.1 hypothetical protein 1176877 11809359 BCGMEX_1082 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170548.1 1176488 D 717522 CDS YP_005170549.1 378770816 11809360 complement(1176776..1177051) 1 NC_016804.1 hypothetical protein 1177051 11809360 BCGMEX_1083c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170549.1 1176776 R 717522 CDS YP_005170550.1 378770817 11809361 1177693..1178007 1 NC_016804.1 putative integrase 1178007 11809361 BCGMEX_1084 Mycobacterium bovis BCG str. Mexico putative integrase YP_005170550.1 1177693 D 717522 CDS YP_005170551.1 378770818 11809362 1178004..1178138 1 NC_016804.1 putative integrase 1178138 11809362 BCGMEX_1085 Mycobacterium bovis BCG str. Mexico putative integrase YP_005170551.1 1178004 D 717522 CDS YP_005170552.1 378770819 11809364 1178399..1179157 1 NC_016804.1 hypothetical protein 1179157 11809364 BCGMEX_1086 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170552.1 1178399 D 717522 CDS YP_005170553.1 378770820 11809365 1180161..1181342 1 NC_016804.1 hypothetical protein 1181342 11809365 BCGMEX_1087 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170553.1 1180161 D 717522 CDS YP_005170554.1 378770821 11809366 1181449..1183080 1 NC_016804.1 acyl-CoA synthetase 1183080 fadD14 11809366 fadD14 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005170554.1 1181449 D 717522 CDS YP_005170555.1 378770822 11809367 1183156..1184220 1 NC_016804.1 hypothetical protein 1184220 11809367 BCGMEX_1089 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170555.1 1183156 D 717522 CDS YP_005170556.1 378770823 11809368 1184273..1184746 1 NC_016804.1 hypothetical protein 1184746 11809368 BCGMEX_1090 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170556.1 1184273 D 717522 CDS YP_005170557.1 378770824 11809369 1184780..1185643 1 NC_016804.1 hypothetical protein 1185643 11809369 BCGMEX_1091 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170557.1 1184780 D 717522 CDS YP_005170558.1 378770825 11809370 1185648..1186505 1 NC_016804.1 hypothetical protein 1186505 11809370 BCGMEX_1092 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170558.1 1185648 D 717522 CDS YP_005170559.1 378770826 11809371 complement(1186506..1187588) 1 NC_016804.1 hypothetical protein 1187588 11809371 BCGMEX_1093c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170559.1 1186506 R 717522 CDS YP_005170560.1 378770827 11809372 complement(1187669..1188088) 1 NC_016804.1 putative lipoprotein 1188088 lpqV 11809372 lpqV Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170560.1 1187669 R 717522 CDS YP_005170561.1 378770828 11809373 1188200..1188766 1 NC_016804.1 hypothetical protein 1188766 11809373 BCGMEX_1095 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170561.1 1188200 D 717522 CDS YP_005170562.1 378770829 11809374 1188763..1189158 1 NC_016804.1 hypothetical protein 1189158 11809374 BCGMEX_1096 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170562.1 1188763 D 717522 CDS YP_005170563.1 378770830 11809375 complement(1189186..1191201) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo, and BCG Mexico, 2 deletions each of 3 bp and a 18 bp insertion leads to a longer product compared to their homolog in Mycobacterium tuberculosis strain H37Rv (671 aa versus 667 aa); PE-PGRS family protein 1191201 PE_PGRS19 11809375 PE_PGRS19 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170563.1 1189186 R 717522 CDS YP_005170564.1 378770831 11809376 complement(1191534..1193726) 1 NC_016804.1 In Mycobacterium bovis, insertions of 717 bp and 192 bp, and a 9 bp deletion, leads to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (763 aa versus 463 aa). In Mycobacterium bovis BCG Pasteur a deletion of 99 bp leads to a smaller product compared to the homolog in Mycobacterium bovis (730 aa versus 763 aa); PE-PGRS family protein 1193726 11809376 BCGMEX_1098c Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170564.1 1191534 R 717522 CDS YP_005170565.1 378770832 11809377 complement(1194088..1195851) 1 NC_016804.1 Differs from Rv1069c and from Mb1098c by 1aa L481P in BCG Pasteur, BCG Tokyo and BCG Mexico.; hypothetical protein 1195851 11809377 BCGMEX_1099c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170565.1 1194088 R 717522 CDS YP_005170566.1 378770833 11809378 complement(1195848..1196621) 1 NC_016804.1 Enoyl-CoA hydratase 1196621 echA8 11809378 echA8 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170566.1 1195848 R 717522 CDS YP_005170567.1 378770834 11809379 complement(1196633..1197670) 1 NC_016804.1 Enoyl-CoA hydratase 1197670 echA9 11809379 echA9 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170567.1 1196633 R 717522 CDS YP_005170568.1 378770835 11809380 1197857..1198693 1 NC_016804.1 transmembrane protein 1198693 11809380 BCGMEX_1102 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005170568.1 1197857 D 717522 CDS YP_005170569.1 378770836 11809381 1198809..1199660 1 NC_016804.1 hypothetical protein 1199660 11809381 BCGMEX_1103 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170569.1 1198809 D 717522 CDS YP_005170570.1 378770837 11809382 complement(1199734..1200951) 1 NC_016804.1 acetyl-CoA acetyltransferase 1200951 fadA3 11809382 fadA3 Mycobacterium bovis BCG str. Mexico acetyl-CoA acetyltransferase YP_005170570.1 1199734 R 717522 CDS YP_005170571.1 378770838 11809383 complement(1201004..1201948) 1 NC_016804.1 hypothetical protein 1201948 11809383 BCGMEX_1105c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170571.1 1201004 R 717522 CDS YP_005170572.1 378770839 11809384 1202345..1203238 1 NC_016804.1 putative lipase 1203238 lipU 11809384 lipU Mycobacterium bovis BCG str. Mexico putative lipase YP_005170572.1 1202345 D 717522 CDS YP_005170573.1 378770840 11809385 1203295..1204689 1 NC_016804.1 putative cystathionine beta-synthase 1204689 cbs 11809385 cbs Mycobacterium bovis BCG str. Mexico putative cystathionine beta-synthase YP_005170573.1 1203295 D 717522 CDS YP_005170574.1 378770841 11809386 1204891..1205613 1 NC_016804.1 Differs from Rv1078 by 1aa T171I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1205613 pra 11809386 pra Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170574.1 1204891 D 717522 CDS YP_005170575.1 378770842 11809387 1205645..1206811 1 NC_016804.1 cystathionine gamma-synthase 1206811 metB 11809387 metB Mycobacterium bovis BCG str. Mexico cystathionine gamma-synthase YP_005170575.1 1205645 D 717522 CDS YP_005170576.1 378770843 11809388 complement(1206882..1207376) 1 NC_016804.1 putative transcription elongation factor 1207376 greA 11809388 greA Mycobacterium bovis BCG str. Mexico putative transcription elongation factor YP_005170576.1 1206882 R 717522 CDS YP_005170577.1 378770844 11809389 complement(1207562..1207996) 1 NC_016804.1 hypothetical protein 1207996 11809389 BCGMEX_1111c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170577.1 1207562 R 717522 CDS YP_005170578.1 378770845 11809390 1208098..1208964 1 NC_016804.1 Mycothiol S-conjugate amidase 1208964 mca 11809390 mca Mycobacterium bovis BCG str. Mexico Mycothiol S-conjugate amidase YP_005170578.1 1208098 D 717522 CDS YP_005170579.1 378770846 11809391 1208961..1209227 1 NC_016804.1 hypothetical protein 1209227 11809391 BCGMEX_1113 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170579.1 1208961 D 717522 CDS YP_005170580.1 378770847 11809392 1209214..1211235 1 NC_016804.1 hypothetical protein 1211235 11809392 BCGMEX_1114 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170580.1 1209214 D 717522 CDS YP_005170581.1 378770848 11809393 complement(1211334..1212062) 1 NC_016804.1 putative hemolysin-like protein 1212062 11809393 BCGMEX_1115c Mycobacterium bovis BCG str. Mexico putative hemolysin-like protein YP_005170581.1 1211334 R 717522 CDS YP_005170582.1 378770849 11809394 1212173..1212961 1 NC_016804.1 Short (C15) chain Z-isoprenyl diphosphate synthase 1212961 11809394 BCGMEX_1116 Mycobacterium bovis BCG str. Mexico Short (C15) chain Z-isoprenyl diphosphate synthase YP_005170582.1 1212173 D 717522 CDS YP_005170583.1 378770850 11809395 1213138..1215567 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, insertions of 144 bp and 3 bp, and deletion of 42 bp, lead to a longer product compared to the homolog in Mycobacterium bovis (809 aa versus 774 aa). In Mycobacterium bovis, insertions of 3 bp and 45 bp, and deletions of 18 bp and 9 bp, lead to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (774 aa versus 767 aa); PE-PGRS family protein 1215567 PE_PGRS21 11809395 PE_PGRS21 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170583.1 1213138 D 717522 CDS YP_005170584.1 378770851 11809396 1215744..1216064 1 NC_016804.1 hypothetical protein 1216064 11809396 BCGMEX_1118 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170584.1 1215744 D 717522 CDS YP_005170585.1 378770852 11809397 1216217..1216651 1 NC_016804.1 PE family protein 1216651 PE9 11809397 PE9 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170585.1 1216217 D 717522 CDS YP_005170586.1 378770853 11809398 1216530..1216835 1 NC_016804.1 Differs from Rv1089 and Mb1118 by 1 aa N84T in BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 1216835 PE10 11809398 PE10 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170586.1 1216530 D 717522 CDS YP_005170587.1 378770854 11809399 1217221..1217325 1 NC_016804.1 putative cellulase 1217325 celA2a 11809399 celA2a Mycobacterium bovis BCG str. Mexico putative cellulase YP_005170587.1 1217221 D 717522 CDS YP_005170588.1 378770855 11809400 1217303..1217758 1 NC_016804.1 putative cellulase 1217758 celA2b 11809400 celA2b Mycobacterium bovis BCG str. Mexico putative cellulase YP_005170588.1 1217303 D 717522 CDS YP_005170589.1 378770856 11809401 1218173..1220725 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 9 bp deletion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (850 aa versus 853 aa); PE PGRS family protein 1220725 PE_PGRS22 11809401 PE_PGRS22 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005170589.1 1218173 D 717522 CDS YP_005170590.1 378770857 11809402 complement(1220943..1221881) 1 NC_016804.1 Pantothenate kinase 1221881 coaA 11809402 coaA Mycobacterium bovis BCG str. Mexico Pantothenate kinase YP_005170590.1 1220943 R 717522 CDS YP_005170591.1 378770858 11809403 1222269..1223549 1 NC_016804.1 Differs from Rv1093 by 1aa, A36V in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; Serine hydroxymethyltransferase 1223549 glyA 11809403 glyA Mycobacterium bovis BCG str. Mexico Serine hydroxymethyltransferase YP_005170591.1 1222269 D 717522 CDS YP_005170592.1 378770859 11809404 1223654..1224481 1 NC_016804.1 putative acyl-[acyl-carrier protein] desaturase 1224481 desA2 11809404 desA2 Mycobacterium bovis BCG str. Mexico putative acyl-[acyl-carrier protein] desaturase YP_005170592.1 1223654 D 717522 CDS YP_005170593.1 378770860 11809405 1224692..1225993 1 NC_016804.1 putative phoH-like protein 1225993 phoH2 11809405 phoH2 Mycobacterium bovis BCG str. Mexico putative phoH-like protein YP_005170593.1 1224692 D 717522 CDS YP_005170594.1 378770861 11809406 1226080..1226955 1 NC_016804.1 Differs from Rv1096 by 1aa, S272P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative glycosyl hydrolase 1226955 11809406 BCGMEX_1128 Mycobacterium bovis BCG str. Mexico putative glycosyl hydrolase YP_005170594.1 1226080 D 717522 CDS YP_005170595.1 378770862 11809407 complement(1226958..1227839) 1 NC_016804.1 Differs from Rv1097c by 1aa, L23P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative membrane glycine and proline rich protein 1227839 11809407 BCGMEX_1129c Mycobacterium bovis BCG str. Mexico putative membrane glycine and proline rich protein YP_005170595.1 1226958 R 717522 CDS YP_005170596.1 378770863 11809408 complement(1227836..1229260) 1 NC_016804.1 Fumarate hydratase 1229260 fumC 11809408 fumC Mycobacterium bovis BCG str. Mexico Fumarate hydratase YP_005170596.1 1227836 R 717522 CDS YP_005170597.1 378770864 11809409 complement(1229291..1230277) 1 NC_016804.1 Fructose-1,6-bisphosphatase II 1230277 glpX 11809409 glpX Mycobacterium bovis BCG str. Mexico Fructose-1,6-bisphosphatase II YP_005170597.1 1229291 R 717522 CDS YP_005170598.1 378770865 11809410 1230378..1231079 1 NC_016804.1 Differs from Rv1100 and Mb1130 by 1aa, P21T in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1231079 11809410 BCGMEX_1132 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170598.1 1230378 D 717522 CDS YP_005170599.1 378770866 11809411 complement(1231086..1232114) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base deletion leads to a shorter product with a different amino part compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Differs from Mb1131c by 1 aa, E315D in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1232114 11809411 BCGMEX_1133c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170599.1 1231086 R 717522 CDS YP_005170600.1 378770867 11809412 complement(1232354..1232665) 1 NC_016804.1 Differs from Rv1102c by 1aa, I65T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1232665 11809412 BCGMEX_1134c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170600.1 1232354 R 717522 CDS YP_005170601.1 378770868 11809413 complement(1232665..1232985) 1 NC_016804.1 hypothetical protein 1232985 11809413 BCGMEX_1135c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170601.1 1232665 R 717522 CDS YP_005170602.1 378770869 11809414 1232995..1233684 1 NC_016804.1 putative para-nitrobenzyl esterase 1233684 11809414 BCGMEX_1136 Mycobacterium bovis BCG str. Mexico putative para-nitrobenzyl esterase YP_005170602.1 1232995 D 717522 CDS YP_005170603.1 378770870 11809415 1234005..1234520 1 NC_016804.1 putative para-nitrobenzyl esterase 1234520 11809415 BCGMEX_1137 Mycobacterium bovis BCG str. Mexico putative para-nitrobenzyl esterase YP_005170603.1 1234005 D 717522 CDS YP_005170604.1 378770871 11809416 complement(1234538..1235638) 1 NC_016804.1 putative cholesterol dehydrogenase 1235638 11809416 BCGMEX_1138c Mycobacterium bovis BCG str. Mexico putative cholesterol dehydrogenase YP_005170604.1 1234538 R 717522 CDS YP_005170605.1 378770872 11809417 complement(1235660..1235917) 1 NC_016804.1 Exodeoxyribonuclease VII small subunit 1235917 xseB 11809417 xseB Mycobacterium bovis BCG str. Mexico Exodeoxyribonuclease VII small subunit YP_005170605.1 1235660 R 717522 CDS YP_005170606.1 378770873 11809418 complement(1235907..1237154) 1 NC_016804.1 Exodeoxyribonuclease VII large subunit 1237154 xseA 11809418 xseA Mycobacterium bovis BCG str. Mexico Exodeoxyribonuclease VII large subunit YP_005170606.1 1235907 R 717522 CDS YP_005170607.1 378770874 11809419 complement(1237151..1237789) 1 NC_016804.1 Differs from Rv1109c and Mb1139c by 1aa, T147A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1237789 11809419 BCGMEX_1141c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170607.1 1237151 R 717522 CDS YP_005170608.1 378770875 11809420 1237879..1238886 1 NC_016804.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1238886 lytB 11809420 lytB Mycobacterium bovis BCG str. Mexico 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_005170608.1 1237879 D 717522 CDS YP_005170609.1 378770876 11809421 complement(1238903..1239886) 1 NC_016804.1 hypothetical protein 1239886 11809421 BCGMEX_1143c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170609.1 1238903 R 717522 CDS YP_005170610.1 378770877 11809422 1239949..1241022 1 NC_016804.1 Differs from Rv1112 by 1aa, I77V in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; Translation-associated GTPase 1241022 ychF 11809422 ychF Mycobacterium bovis BCG str. Mexico Translation-associated GTPase YP_005170610.1 1239949 D 717522 CDS YP_005170611.1 378770878 11809423 1241110..1241307 1 NC_016804.1 hypothetical protein 1241307 11809423 BCGMEX_1145 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170611.1 1241110 D 717522 CDS YP_005170612.1 378770879 11809424 1241304..1241678 1 NC_016804.1 hypothetical protein 1241678 11809424 BCGMEX_1146 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170612.1 1241304 D 717522 CDS YP_005170613.1 378770880 11809425 1241881..1242579 1 NC_016804.1 Differs from Rv1115 by 1aa, P19S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1242579 11809425 BCGMEX_1147 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170613.1 1241881 D 717522 CDS YP_005170614.1 378770881 11809426 1242697..1242882 1 NC_016804.1 hypothetical protein 1242882 11809426 BCGMEX_1148 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170614.1 1242697 D 717522 CDS YP_005170615.1 378770882 11809427 complement(1242809..1243084) 1 NC_016804.1 hypothetical protein 1243084 11809427 BCGMEX_1149c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170615.1 1242809 R 717522 CDS YP_005170616.1 378770883 11809428 1243327..1243650 1 NC_016804.1 hypothetical protein 1243650 11809428 BCGMEX_1150 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170616.1 1243327 D 717522 CDS YP_005170617.1 378770884 11809429 complement(1243665..1244525) 1 NC_016804.1 hypothetical protein 1244525 11809429 BCGMEX_1151c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170617.1 1243665 R 717522 CDS YP_005170618.1 378770885 11809430 complement(1244558..1244707) 1 NC_016804.1 hypothetical protein 1244707 11809430 BCGMEX_1152c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170618.1 1244558 R 717522 CDS YP_005170619.1 378770886 11809431 complement(1244704..1245198) 1 NC_016804.1 Differs from Mb1151c by 1aa, G53A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1245198 11809431 BCGMEX_1153c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170619.1 1244704 R 717522 CDS YP_005170620.1 378770887 11809432 1245401..1246801 1 NC_016804.1 glucose-6-phosphate 1-dehydrogenase 1246801 zwf1 11809432 zwf1 Mycobacterium bovis BCG str. Mexico glucose-6-phosphate 1-dehydrogenase YP_005170620.1 1245401 D 717522 CDS YP_005170621.1 378770888 11809433 1246823..1247845 1 NC_016804.1 6-phosphogluconate dehydrogenase like protein 1247845 gnd2 11809433 gnd2 Mycobacterium bovis BCG str. Mexico 6-phosphogluconate dehydrogenase like protein YP_005170621.1 1246823 D 717522 CDS YP_005170622.1 378770889 11809434 complement(1247838..1248746) 1 NC_016804.1 putative peroxidase 1248746 bpoB 11809434 bpoB Mycobacterium bovis BCG str. Mexico putative peroxidase YP_005170622.1 1247838 R 717522 CDS YP_005170623.1 378770890 11809435 1248821..1249771 1 NC_016804.1 putative epoxide hydrolase 1249771 ephC 11809435 ephC Mycobacterium bovis BCG str. Mexico putative epoxide hydrolase YP_005170623.1 1248821 D 717522 CDS YP_005170624.1 378770891 11809436 1249776..1251020 1 NC_016804.1 Differs from Rv1125 by 1aa, G101S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1251020 11809436 BCGMEX_1158 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170624.1 1249776 D 717522 CDS YP_005170625.1 378770892 11809437 complement(1251024..1251629) 1 NC_016804.1 hypothetical protein 1251629 11809437 BCGMEX_1159c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170625.1 1251024 R 717522 CDS YP_005170626.1 378770893 11809438 complement(1251626..1253098) 1 NC_016804.1 Differs from Rv1127c by 2aa, E69G, P350T; putative pyruvate, phosphate dikinase 1253098 ppdK 11809438 ppdK Mycobacterium bovis BCG str. Mexico putative pyruvate, phosphate dikinase YP_005170626.1 1251626 R 717522 CDS YP_005170627.1 378770894 11809439 complement(1253311..1254666) 1 NC_016804.1 Differs from Rv1128c by 1aa, G270E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1254666 11809439 BCGMEX_1161c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170627.1 1253311 R 717522 CDS YP_005170628.1 378770895 11809440 complement(1254768..1256228) 1 NC_016804.1 putative transcriptional regulator protein 1256228 11809440 BCGMEX_1162c Mycobacterium bovis BCG str. Mexico putative transcriptional regulator protein YP_005170628.1 1254768 R 717522 CDS YP_005170629.1 378770896 11809441 1256249..1257829 1 NC_016804.1 Differs from Rv1130 by 2aa, G3D, L10F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1257829 11809441 BCGMEX_1163 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170629.1 1256249 D 717522 CDS YP_005170630.1 378770897 11809442 1257826..1259007 1 NC_016804.1 methylcitrate synthase 1259007 gltA1 11809442 gltA1 Mycobacterium bovis BCG str. Mexico methylcitrate synthase YP_005170630.1 1257826 D 717522 CDS YP_005170631.1 378770898 11809443 1259019..1260749 1 NC_016804.1 Differs from Mb1163 by 1aa, T176M in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1260749 11809443 BCGMEX_1165 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170631.1 1259019 D 717522 CDS YP_005170632.1 378770899 11809444 complement(1260761..1263040) 1 NC_016804.1 putative 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1263040 metE 11809444 metE Mycobacterium bovis BCG str. Mexico putative 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase YP_005170632.1 1260761 R 717522 CDS YP_005170633.1 378770900 11809445 1263616..1263852 1 NC_016804.1 hypothetical protein 1263852 11809445 BCGMEX_1167 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170633.1 1263616 D 717522 CDS YP_005170634.1 378770901 11809446 complement(1263966..1265822) 1 NC_016804.1 PPE family protein 1265822 PPE16 11809446 PPE16 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170634.1 1263966 R 717522 CDS YP_005170635.1 378770902 11809447 1266008..1266250 1 NC_016804.1 putative acetyl-CoA acetyltransferase 1266250 11809447 BCGMEX_1169 Mycobacterium bovis BCG str. Mexico putative acetyl-CoA acetyltransferase YP_005170635.1 1266008 D 717522 CDS YP_005170636.1 378770903 11809448 1266300..1266641 1 NC_016804.1 putative enoyl-CoA hydratase 1266641 11809448 BCGMEX_1170 Mycobacterium bovis BCG str. Mexico putative enoyl-CoA hydratase YP_005170636.1 1266300 D 717522 CDS YP_005170637.1 378770904 11809449 complement(1266781..1267149) 1 NC_016804.1 hypothetical protein 1267149 11809449 BCGMEX_1171c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170637.1 1266781 R 717522 CDS YP_005170638.1 378770905 11809450 complement(1267166..1268182) 1 NC_016804.1 putative oxidoreductase 1268182 11809450 BCGMEX_1172c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170638.1 1267166 R 717522 CDS YP_005170639.1 378770906 11809451 complement(1268179..1268679) 1 NC_016804.1 hypothetical protein 1268679 11809451 BCGMEX_1173c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170639.1 1268179 R 717522 CDS YP_005170640.1 378770907 11809452 1269041..1269889 1 NC_016804.1 putative integral membrane protein 1269889 11809452 BCGMEX_1174 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170640.1 1269041 D 717522 CDS YP_005170641.1 378770908 11809453 complement(1269897..1270703) 1 NC_016804.1 Enoyl-CoA hydratase 1270703 echA11 11809453 echA11 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170641.1 1269897 R 717522 CDS YP_005170642.1 378770909 11809454 complement(1270846..1271652) 1 NC_016804.1 Enoyl-CoA hydratase 1271652 echA10 11809454 echA10 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170642.1 1270846 R 717522 CDS YP_005170643.1 378770910 11809455 1271756..1272838 1 NC_016804.1 putative alpha-methylacyl-CoA racemase 1272838 mcr 11809455 mcr Mycobacterium bovis BCG str. Mexico putative alpha-methylacyl-CoA racemase YP_005170643.1 1271756 D 717522 CDS YP_005170644.1 378770911 11809456 1272850..1273602 1 NC_016804.1 putative short-chain type dehydrogenase/reductase 1273602 11809456 BCGMEX_1178 Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005170644.1 1272850 D 717522 CDS YP_005170645.1 378770912 11809457 1274117..1276462 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1145 and Rv1146 exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG MExico, and Mycobacterium bovis, a single base insertion at H37Rv position 1273250-1273251 leads to a single product; transmembrane transport protein 1276462 mmpL13 11809457 mmpL13 Mycobacterium bovis BCG str. Mexico transmembrane transport protein YP_005170645.1 1274117 D 717522 CDS YP_005170646.1 378770913 11809458 1276595..1277245 1 NC_016804.1 hypothetical protein 1277245 11809458 BCGMEX_1180 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170646.1 1276595 D 717522 CDS YP_005170647.1 378770914 11809459 complement(1277995..1279443) 1 NC_016804.1 Differs from Rv1148c and Mb1179c by 1aa, N354H in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1279443 11809459 BCGMEX_1181c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170647.1 1277995 R 717522 CDS YP_005170648.1 378770915 11809460 1279588..1279995 1 NC_016804.1 putative transposase 1279995 11809460 BCGMEX_1182 Mycobacterium bovis BCG str. Mexico putative transposase YP_005170648.1 1279588 D 717522 CDS YP_005170649.1 378770916 11809462 complement(1280599..1281312) 1 NC_016804.1 NAD-dependent deacetylase 1281312 11809462 BCGMEX_1184c Mycobacterium bovis BCG str. Mexico NAD-dependent deacetylase YP_005170649.1 1280599 R 717522 CDS YP_005170650.1 378770917 11809463 1281350..1281715 1 NC_016804.1 putative transcriptional regulatory protein 1281715 11809463 BCGMEX_1185 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170650.1 1281350 D 717522 CDS YP_005170651.1 378770918 11809464 complement(1281693..1282541) 1 NC_016804.1 Differs from Rv1153c by 2aa, T36A, G53D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; putative O-methyltransferase 1282541 omt 11809464 omt Mycobacterium bovis BCG str. Mexico putative O-methyltransferase YP_005170651.1 1281693 R 717522 CDS YP_005170652.1 378770919 11809465 complement(1282538..1283179) 1 NC_016804.1 Differs from Rv1154c by 1aa, A123T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1283179 11809465 BCGMEX_1187c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170652.1 1282538 R 717522 CDS YP_005170653.1 378770920 11809466 1283124..1283567 1 NC_016804.1 Differs from Rv1155 by 1aa, P115S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1283567 11809466 BCGMEX_1188 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170653.1 1283124 D 717522 CDS YP_005170654.1 378770921 11809467 1284001..1284588 1 NC_016804.1 hypothetical protein 1284588 11809467 BCGMEX_1189 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170654.1 1284001 D 717522 CDS YP_005170655.1 378770922 11809468 complement(1284751..1285794) 1 NC_016804.1 Is 24 codons shorter than Rv1157c and Mb1188c due to 72bp deletion, after codon 214; hypothetical protein 1285794 11809468 BCGMEX_1190c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170655.1 1284751 R 717522 CDS YP_005170656.1 378770923 11809469 complement(1285802..1286485) 1 NC_016804.1 hypothetical protein 1286485 11809469 BCGMEX_1191c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170656.1 1285802 R 717522 CDS YP_005170657.1 378770924 11809470 1286615..1287910 1 NC_016804.1 Mannosyltransferase 1287910 pimE 11809470 pimE Mycobacterium bovis BCG str. Mexico Mannosyltransferase YP_005170657.1 1286615 D 717522 CDS YP_005170658.1 378770925 11809471 complement(1287907..1288191) 1 NC_016804.1 Pterin-4-alpha-carbinolamine dehydratase 1288191 phhB 11809471 phhB Mycobacterium bovis BCG str. Mexico Pterin-4-alpha-carbinolamine dehydratase YP_005170658.1 1287907 R 717522 CDS YP_005170659.1 378770926 11809472 1288218..1288643 1 NC_016804.1 putative mutator protein 1288643 mutT2 11809472 mutT2 Mycobacterium bovis BCG str. Mexico putative mutator protein YP_005170659.1 1288218 D 717522 CDS YP_005170660.1 378770927 11809473 1288951..1292649 1 NC_016804.1 Differs from Rv1161 by 2aa, L458V, G821D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative respiratory nitrate reductase alpha chain 1292649 narG 11809473 narG Mycobacterium bovis BCG str. Mexico putative respiratory nitrate reductase alpha chain YP_005170660.1 1288951 D 717522 CDS YP_005170661.1 378770928 11809474 1292688..1294364 1 NC_016804.1 putative respiratory nitrate reductase beta chain 1294364 narH 11809474 narH Mycobacterium bovis BCG str. Mexico putative respiratory nitrate reductase beta chain YP_005170661.1 1292688 D 717522 CDS YP_005170662.1 378770929 11809475 1294421..1295026 1 NC_016804.1 Differs from Rv1163 and Mb1195 by 1aa, L106P in Mycobacterium bovis BCG Pasteur; putative respiratory nitrate reductase delta chain 1295026 narJ 11809475 narJ Mycobacterium bovis BCG str. Mexico putative respiratory nitrate reductase delta chain YP_005170662.1 1294421 D 717522 CDS YP_005170663.1 378770930 11809476 1295029..1295769 1 NC_016804.1 Differs from Rv1164 by 1aa, V200A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative respiratory nitrate reductase gamma chain 1295769 narI 11809476 narI Mycobacterium bovis BCG str. Mexico putative respiratory nitrate reductase gamma chain YP_005170663.1 1295029 D 717522 CDS YP_005170664.1 378770931 11809477 1295791..1297677 1 NC_016804.1 Differs from Rv1165, Mb1197 by 1aa L98V in Mycobacterium bovis BCG Tokyo.; putative GTP-binding translation elongation factor 1297677 typA 11809477 typA Mycobacterium bovis BCG str. Mexico putative GTP-binding translation elongation factor YP_005170664.1 1295791 D 717522 CDS YP_005170665.1 378770932 11809478 1297775..1299682 1 NC_016804.1 putative lipoprotein 1299682 lpqW 11809478 lpqW Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170665.1 1297775 D 717522 CDS YP_005170666.1 378770933 11809479 complement(1299710..1300315) 1 NC_016804.1 putative transcriptional regulatory protein 1300315 11809479 BCGMEX_1201c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170666.1 1299710 R 717522 CDS YP_005170667.1 378770934 11809481 complement(1300886..1301428) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE17 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base insertion splits PPE17 into 2 parts, PPE17a and PPE17b; PPE family protein 1301428 PPE17a 11809481 PPE17a Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170667.1 1300886 R 717522 CDS YP_005170668.1 378770935 11809482 complement(1301446..1301748) 1 NC_016804.1 PE family protein 1301748 PE11 11809482 PE11 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170668.1 1301446 R 717522 CDS YP_005170669.1 378770936 11809483 1301928..1302839 1 NC_016804.1 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase 1302839 mshB 11809483 mshB Mycobacterium bovis BCG str. Mexico N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase YP_005170669.1 1301928 D 717522 CDS YP_005170670.1 378770937 11809484 1302931..1303371 1 NC_016804.1 hypothetical protein 1303371 11809484 BCGMEX_1206 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170670.1 1302931 D 717522 CDS YP_005170671.1 378770938 11809485 complement(1303379..1304305) 1 NC_016804.1 Differs from Rv1172c by 1aa, H133Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 1304305 PE12 11809485 PE12 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170671.1 1303379 R 717522 CDS YP_005170672.1 378770939 11809486 1304555..1307125 1 NC_016804.1 FO synthase 1307125 fbiC 11809486 fbiC Mycobacterium bovis BCG str. Mexico FO synthase YP_005170672.1 1304555 D 717522 CDS YP_005170673.1 378770940 11809487 complement(1307231..1307563) 1 NC_016804.1 hypothetical protein 1307563 11809487 BCGMEX_1209c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170673.1 1307231 R 717522 CDS YP_005170674.1 378770941 11809488 complement(1307764..1309788) 1 NC_016804.1 Differs from Rv1175c by 3aa, N90T, S210T, S649I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative NADPH dependent 2,4-dienoyl-CoA reductase 1309788 fadH 11809488 fadH Mycobacterium bovis BCG str. Mexico putative NADPH dependent 2,4-dienoyl-CoA reductase YP_005170674.1 1307764 R 717522 CDS YP_005170675.1 378770942 11809489 complement(1309785..1310354) 1 NC_016804.1 hypothetical protein 1310354 11809489 BCGMEX_1211c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170675.1 1309785 R 717522 CDS YP_005170676.1 378770943 11809490 1310567..1310893 1 NC_016804.1 putative ferredoxin 1310893 fdxC 11809490 fdxC Mycobacterium bovis BCG str. Mexico putative ferredoxin YP_005170676.1 1310567 D 717522 CDS YP_005170677.1 378770944 11809491 1310926..1312014 1 NC_016804.1 N-succinyl-L,L-diaminopimelate aminotransferase 1312014 11809491 BCGMEX_1213 Mycobacterium bovis BCG str. Mexico N-succinyl-L,L-diaminopimelate aminotransferase YP_005170677.1 1310926 D 717522 CDS YP_005170678.1 378770945 11809492 complement(1312042..1314861) 1 NC_016804.1 hypothetical protein 1314861 11809492 BCGMEX_1214c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170678.1 1312042 R 717522 CDS YP_005170679.1 378770946 11809493 1315288..1321545 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1180 and Rv1181 exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a single base transversion leads to a single product (similar to other organisms). Differs from Rv1181 by 2aa, A1068D, P1423A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyketide beta-ketoacyl synthase 1321545 pks3 11809493 pks3 Mycobacterium bovis BCG str. Mexico putative polyketide beta-ketoacyl synthase YP_005170679.1 1315288 D 717522 CDS YP_005170680.1 378770947 11809494 1321598..1323016 1 NC_016804.1 putative polyketide synthase associated protein 1323016 papA3 11809494 papA3 Mycobacterium bovis BCG str. Mexico putative polyketide synthase associated protein YP_005170680.1 1321598 D 717522 CDS YP_005170681.1 378770948 11809495 1323083..1326091 1 NC_016804.1 putative transmembrane protein 1326091 mmpL10 11809495 mmpL10 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170681.1 1323083 D 717522 CDS YP_005170682.1 378770949 11809496 complement(1326095..1327174) 1 NC_016804.1 hypothetical protein 1327174 11809496 BCGMEX_1218c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170682.1 1326095 R 717522 CDS YP_005170683.1 378770950 11809497 complement(1327339..1329075) 1 NC_016804.1 acyl-CoA synthetase 1329075 fadD21 11809497 fadD21 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005170683.1 1327339 R 717522 CDS YP_005170684.1 378770951 11809498 complement(1329252..1330868) 1 NC_016804.1 Differs from Rv1186c by 1aa, A207P in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1330868 11809498 BCGMEX_1220c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170684.1 1329252 R 717522 CDS YP_005170685.1 378770952 11809499 1330953..1332584 1 NC_016804.1 putative pyrroline-5-carboxylate dehydrogenase 1332584 rocA 11809499 rocA Mycobacterium bovis BCG str. Mexico putative pyrroline-5-carboxylate dehydrogenase YP_005170685.1 1330953 D 717522 CDS YP_005170686.1 378770953 11809500 1332584..1333573 1 NC_016804.1 putative proline dehydrogenase 1333573 11809500 BCGMEX_1222 Mycobacterium bovis BCG str. Mexico putative proline dehydrogenase YP_005170686.1 1332584 D 717522 CDS YP_005170687.1 378770954 11809501 1333655..1334860 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv and Mycobacterium bovis AF2122/97, sigI (290 aa) and Rv1189/Mb1221 (304 aa) exist as two genes. In Mycobacterium bovis BCG Pasteur and BCG Mexico they have been fused in-frame following a 1548bp deletion (N-RD18) compared to H37Rv; RNA polymerase sigma factor 1334860 sigI 11809501 sigI Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005170687.1 1333655 D 717522 CDS YP_005170688.1 378770955 11809502 1334942..1335769 1 NC_016804.1 hypothetical protein 1335769 11809502 BCGMEX_1224 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170688.1 1334942 D 717522 CDS YP_005170689.1 378770956 11809503 1335809..1337230 1 NC_016804.1 acyl-CoA synthetase 1337230 11809503 BCGMEX_1225 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005170689.1 1335809 D 717522 CDS YP_005170690.1 378770957 11809504 complement(1337263..1338528) 1 NC_016804.1 hypothetical protein 1338528 11809504 BCGMEX_1226c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170690.1 1337263 R 717522 CDS YP_005170691.1 378770958 11809505 1339004..1339303 1 NC_016804.1 PE family protein 1339303 PE13 11809505 PE13 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170691.1 1339004 D 717522 CDS YP_005170692.1 378770959 11809506 1339350..1340522 1 NC_016804.1 In Mycobacterium bovis, a 14 bp to 11 bp substitution leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (390 aa versus 391 aa). Differs extensively from orthologs Mb1228 and Rv1196 due to numerous substitutions and transitions. Region from aa 210 - 260 shows most difference; PPE family protein 1340522 PPE18 11809506 PPE18 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170692.1 1339350 D 717522 CDS YP_005170693.1 378770960 11809507 1340657..1340953 1 NC_016804.1 Differs from Mb1229 by 1aa, A58T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative EsaT-6 like protein 3 1340953 esxK 11809507 esxK Mycobacterium bovis BCG str. Mexico putative EsaT-6 like protein 3 YP_005170693.1 1340657 D 717522 CDS YP_005170694.1 378770961 11809508 1341004..1341288 1 NC_016804.1 Differs from Rv1198 by 1aa, D12A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ESAT-6 like protein 4 1341288 esxL 11809508 esxL Mycobacterium bovis BCG str. Mexico putative ESAT-6 like protein 4 YP_005170694.1 1341004 D 717522 CDS YP_005170695.1 378770962 11809509 complement(1341356..1342603) 1 NC_016804.1 Differs from Rv1199c and Mb1231c by 1aa, G90D in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 1342603 11809509 BCGMEX_1231c Mycobacterium bovis BCG str. Mexico putative transposase YP_005170695.1 1341356 R 717522 CDS YP_005170696.1 378770963 11809510 1342940..1344217 1 NC_016804.1 integral membrane transport protein 1344217 11809510 BCGMEX_1232 Mycobacterium bovis BCG str. Mexico integral membrane transport protein YP_005170696.1 1342940 D 717522 CDS YP_005170697.1 378770964 11809511 complement(1344214..1345167) 1 NC_016804.1 putative transferase 1345167 11809511 BCGMEX_1233c Mycobacterium bovis BCG str. Mexico putative transferase YP_005170697.1 1344214 R 717522 CDS YP_005170698.1 378770965 11809512 1345258..1346322 1 NC_016804.1 dipeptidase 1346322 dapE 11809512 dapE Mycobacterium bovis BCG str. Mexico dipeptidase YP_005170698.1 1345258 D 717522 CDS YP_005170699.1 378770966 11809513 complement(1346319..1346903) 1 NC_016804.1 hypothetical protein 1346903 11809513 BCGMEX_1235c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170699.1 1346319 R 717522 CDS YP_005170700.1 378770967 11809514 complement(1346934..1348622) 1 NC_016804.1 hypothetical protein 1348622 11809514 BCGMEX_1236c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170700.1 1346934 R 717522 CDS YP_005170701.1 378770968 11809515 1348717..1349280 1 NC_016804.1 hypothetical protein 1349280 11809515 BCGMEX_1237 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170701.1 1348717 D 717522 CDS YP_005170702.1 378770969 11809516 1349330..1351123 1 NC_016804.1 acyl-CoA synthetase 1351123 fadD6 11809516 fadD6 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005170702.1 1349330 D 717522 CDS YP_005170703.1 378770970 11809517 1351189..1352145 1 NC_016804.1 putative dihydropteroate synthase 2 1352145 folP2 11809517 folP2 Mycobacterium bovis BCG str. Mexico putative dihydropteroate synthase 2 YP_005170703.1 1351189 D 717522 CDS YP_005170704.1 378770971 11809518 1352142..1353116 1 NC_016804.1 hypothetical protein 1353116 11809518 BCGMEX_1240 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170704.1 1352142 D 717522 CDS YP_005170705.1 378770972 11809519 1353155..1353523 1 NC_016804.1 hypothetical protein 1353523 11809519 BCGMEX_1241 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170705.1 1353155 D 717522 CDS YP_005170706.1 378770973 11809520 1353520..1354134 1 NC_016804.1 putative DNA-3-methyladenine glycosylase I 1354134 tagA 11809520 tagA Mycobacterium bovis BCG str. Mexico putative DNA-3-methyladenine glycosylase I YP_005170706.1 1353520 D 717522 CDS YP_005170707.1 378770974 11809521 1354242..1354469 1 NC_016804.1 hypothetical protein 1354469 11809521 BCGMEX_1243 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170707.1 1354242 D 717522 CDS YP_005170708.1 378770975 11809522 complement(1354497..1355660) 1 NC_016804.1 Differs from Rv1212c by 2aa, I105V, W340L and from Mb1244c by 1aa, W340L in BCG Pasteur, BCG Tokyo and BCG Mexico; putative glycosyl transferase 1355660 11809522 BCGMEX_1244c Mycobacterium bovis BCG str. Mexico putative glycosyl transferase YP_005170708.1 1354497 R 717522 CDS YP_005170709.1 378770976 11809523 1355835..1357049 1 NC_016804.1 glucose-1-phosphate adenylyltransferase 1357049 glgC 11809523 glgC Mycobacterium bovis BCG str. Mexico glucose-1-phosphate adenylyltransferase YP_005170709.1 1355835 D 717522 CDS YP_005170710.1 378770977 11809524 complement(1357292..1357624) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, and Mycobacterium tuberculosis strain H37Rv, PE14 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 5 bp deletion leads to a diffferent COOH terminus; PE family protein 1357624 PE14 11809524 PE14 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170710.1 1357292 R 717522 CDS YP_005170711.1 378770978 11809525 complement(1357758..1359443) 1 NC_016804.1 Differs from Rv1215c by 1aa, S169A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1359443 11809525 BCGMEX_1247c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170711.1 1357758 R 717522 CDS YP_005170712.1 378770979 11809526 complement(1359471..1360145) 1 NC_016804.1 putative integral membrane protein 1360145 11809526 BCGMEX_1248c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170712.1 1359471 R 717522 CDS YP_005170713.1 378770980 11809527 complement(1360154..1361800) 1 NC_016804.1 Differs from Mb1249c by 1aa, A143T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative tetronasin-transport integral membrane protein ABC transporter 1361800 11809527 BCGMEX_1249c Mycobacterium bovis BCG str. Mexico putative tetronasin-transport integral membrane protein ABC transporter YP_005170713.1 1360154 R 717522 CDS YP_005170714.1 378770981 11809528 complement(1361797..1362732) 1 NC_016804.1 Differs from Rv1218c by 1aa, R243Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative tetronasin-transport ATP-binding protein ABC transporter 1362732 11809528 BCGMEX_1250c Mycobacterium bovis BCG str. Mexico putative tetronasin-transport ATP-binding protein ABC transporter YP_005170714.1 1361797 R 717522 CDS YP_005170715.1 378770982 11809529 complement(1362722..1363360) 1 NC_016804.1 Differs from Rv1219c and Mb1251c by 1aa, C113W in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 1363360 11809529 BCGMEX_1251c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170715.1 1362722 R 717522 CDS YP_005170716.1 378770983 11809530 complement(1363502..1364149) 1 NC_016804.1 putative methyltransferase 1364149 11809530 BCGMEX_1252c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005170716.1 1363502 R 717522 CDS YP_005170717.1 378770984 11809531 1364412..1365185 1 NC_016804.1 RNA polymerase sigma factor 1365185 sigE 11809531 sigE Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005170717.1 1364412 D 717522 CDS YP_005170718.1 378770985 11809532 1365343..1365807 1 NC_016804.1 hypothetical protein 1365807 11809532 BCGMEX_1254 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170718.1 1365343 D 717522 CDS YP_005170719.1 378770986 11809533 1365876..1367462 1 NC_016804.1 Differs from Rv1223 by 2aa, L288F, N445S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative serine protease 1367462 htrA 11809533 htrA Mycobacterium bovis BCG str. Mexico putative serine protease YP_005170719.1 1365876 D 717522 CDS YP_005170720.1 378770987 11809534 1367464..1367859 1 NC_016804.1 Differs from Rv1224 by 1aa, G8W in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; sec-independent translocase 1367859 tatB 11809534 tatB Mycobacterium bovis BCG str. Mexico sec-independent translocase YP_005170720.1 1367464 D 717522 CDS YP_005170721.1 378770988 11809535 complement(1367892..1368722) 1 NC_016804.1 hypothetical protein 1368722 11809535 BCGMEX_1257c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170721.1 1367892 R 717522 CDS YP_005170722.1 378770989 11809536 complement(1368833..1370296) 1 NC_016804.1 Differs from Rv1226c by 1aa, A450V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 1370296 11809536 BCGMEX_1258c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170722.1 1368833 R 717522 CDS YP_005170723.1 378770990 11809537 complement(1370293..1370826) 1 NC_016804.1 putative transmembrane protein 1370826 11809537 BCGMEX_1259c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170723.1 1370293 R 717522 CDS YP_005170724.1 378770991 11809538 1370921..1371478 1 NC_016804.1 putative lipoprotein 1371478 lpqX 11809538 lpqX Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170724.1 1370921 D 717522 CDS YP_005170725.1 378770992 11809539 complement(1371778..1372950) 1 NC_016804.1 putative MRP-related protein 1372950 mrp 11809539 mrp Mycobacterium bovis BCG str. Mexico putative MRP-related protein YP_005170725.1 1371778 R 717522 CDS YP_005170726.1 378770993 11809540 complement(1372963..1374198) 1 NC_016804.1 Differs from Rv1230c by 2aa, G45S, P97S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1374198 11809540 BCGMEX_1262c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170726.1 1372963 R 717522 CDS YP_005170727.1 378770994 11809541 complement(1374323..1374865) 1 NC_016804.1 hypothetical protein 1374865 11809541 BCGMEX_1263c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170727.1 1374323 R 717522 CDS YP_005170728.1 378770995 11809542 complement(1374862..1376169) 1 NC_016804.1 Differs from Rv1232c by 1aa, G149C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1376169 11809542 BCGMEX_1264c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170728.1 1374862 R 717522 CDS YP_005170729.1 378770996 11809543 complement(1376231..1376827) 1 NC_016804.1 hypothetical protein 1376827 11809543 BCGMEX_1265c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170729.1 1376231 R 717522 CDS YP_005170730.1 378770997 11809544 1376977..1377504 1 NC_016804.1 putative transmembrane protein 1377504 11809544 BCGMEX_1266 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005170730.1 1376977 D 717522 CDS YP_005170731.1 378770998 11809545 1377525..1378931 1 NC_016804.1 putative sugar-binding lipoprotein 1378931 lpqY 11809545 lpqY Mycobacterium bovis BCG str. Mexico putative sugar-binding lipoprotein YP_005170731.1 1377525 D 717522 CDS YP_005170732.1 378770999 11809546 1378928..1379851 1 NC_016804.1 putative sugar-transport integral membrane protein ABC transporter 1379851 sugA 11809546 sugA Mycobacterium bovis BCG str. Mexico putative sugar-transport integral membrane protein ABC transporter YP_005170732.1 1378928 D 717522 CDS YP_005170733.1 378771000 11809547 1379856..1380680 1 NC_016804.1 putative sugar-transport integral membrane protein ABC transporter 1380680 sugB 11809547 sugB Mycobacterium bovis BCG str. Mexico putative sugar-transport integral membrane protein ABC transporter YP_005170733.1 1379856 D 717522 CDS YP_005170734.1 378771001 11809548 1380685..1381866 1 NC_016804.1 putative sugar-transport ATP-binding protein ABC transporter 1381866 sugC 11809548 sugC Mycobacterium bovis BCG str. Mexico putative sugar-transport ATP-binding protein ABC transporter YP_005170734.1 1380685 D 717522 CDS YP_005170735.1 378771002 11809549 complement(1381943..1383043) 1 NC_016804.1 putative magnesium and cobalt transport transmembrane protein 1383043 corA 11809549 corA Mycobacterium bovis BCG str. Mexico putative magnesium and cobalt transport transmembrane protein YP_005170735.1 1381943 R 717522 CDS YP_005170736.1 378771003 11809550 1383214..1384203 1 NC_016804.1 malate dehydrogenase 1384203 mdh 11809550 mdh Mycobacterium bovis BCG str. Mexico malate dehydrogenase YP_005170736.1 1383214 D 717522 CDS YP_005170737.1 378771004 11809551 1384279..1384539 1 NC_016804.1 hypothetical protein 1384539 11809551 BCGMEX_1273 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170737.1 1384279 D 717522 CDS YP_005170738.1 378771005 11809552 1384536..1384967 1 NC_016804.1 hypothetical protein 1384967 11809552 BCGMEX_1274 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170738.1 1384536 D 717522 CDS YP_005170739.1 378771006 11809553 complement(1384990..1386678) 1 NC_016804.1 PE PGRS family protein 1386678 PE_PGRS23 11809553 PE_PGRS23 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005170739.1 1384990 R 717522 CDS YP_005170740.1 378771007 11809554 1386858..1387718 1 NC_016804.1 Differs from Rv1244 by 1aa, K242Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 1387718 lpqZ 11809554 lpqZ Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170740.1 1386858 D 717522 CDS YP_005170741.1 378771008 11809555 complement(1387799..1388629) 1 NC_016804.1 putative short-chain type dehydrogenase/reductase 1388629 11809555 BCGMEX_1277c Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005170741.1 1387799 R 717522 CDS YP_005170742.1 378771009 11809556 complement(1388686..1388979) 1 NC_016804.1 hypothetical protein 1388979 11809556 BCGMEX_1278c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170742.1 1388686 R 717522 CDS YP_005170743.1 378771010 11809557 complement(1388976..1389245) 1 NC_016804.1 hypothetical protein 1389245 11809557 BCGMEX_1279c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170743.1 1388976 R 717522 CDS YP_005170744.1 378771011 11809558 complement(1389358..1393002) 1 NC_016804.1 Differs from Rv1248c by 1aa, M747V in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; alpha-ketoglutarate decarboxylase 1393002 kgd 11809558 kgd Mycobacterium bovis BCG str. Mexico alpha-ketoglutarate decarboxylase YP_005170744.1 1389358 R 717522 CDS YP_005170745.1 378771012 11809559 complement(1393195..1393983) 1 NC_016804.1 Differs from Rv1249c by 1aa, T95A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1393983 11809559 BCGMEX_1281c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170745.1 1393195 R 717522 CDS YP_005170746.1 378771013 11809560 1394180..1395919 1 NC_016804.1 Differs from Rv1250 by 1aa, G278R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative drug-transport integral membrane protein 1395919 11809560 BCGMEX_1282 Mycobacterium bovis BCG str. Mexico putative drug-transport integral membrane protein YP_005170746.1 1394180 D 717522 CDS YP_005170747.1 378771014 11809561 complement(1395822..1399241) 1 NC_016804.1 hypothetical protein 1399241 11809561 BCGMEX_1283c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170747.1 1395822 R 717522 CDS YP_005170748.1 378771015 11809562 complement(1399297..1399905) 1 NC_016804.1 putative lipoprotein 1399905 lprE 11809562 lprE Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170748.1 1399297 R 717522 CDS YP_005170749.1 378771016 11809563 1399971..1401662 1 NC_016804.1 Differs from Rv1253 by 1aa, V143M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative cold-shock dead-box protein a-like protein 1401662 deaD 11809563 deaD Mycobacterium bovis BCG str. Mexico putative cold-shock dead-box protein a-like protein YP_005170749.1 1399971 D 717522 CDS YP_005170750.1 378771017 11809564 1401659..1402810 1 NC_016804.1 putative acyltransferase 1402810 11809564 BCGMEX_1286 Mycobacterium bovis BCG str. Mexico putative acyltransferase YP_005170750.1 1401659 D 717522 CDS YP_005170751.1 378771018 11809565 complement(1402779..1403078) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 3007 bp deletion (RD13) leads to the fusion of Rv1257c and Rv1255c, and the deletion of Rv1256c, compared to Mycobacterium tuberculosis strain H37Rv; hypothetical protein 1403078 11809565 BCGMEX_1287c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170751.1 1402779 R 717522 CDS YP_005170752.1 378771019 11809566 complement(1403075..1404334) 1 NC_016804.1 putative integral membrane transport protein 1404334 11809566 BCGMEX_1288c Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005170752.1 1403075 R 717522 CDS YP_005170753.1 378771020 11809567 1404333..1405232 1 NC_016804.1 hypothetical protein 1405232 11809567 BCGMEX_1289 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170753.1 1404333 D 717522 CDS YP_005170754.1 378771021 11809568 1405234..1406058 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1260 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base deletion splits Rv1260 into 2 parts; putative oxidoreductase 1406058 11809568 BCGMEX_1290 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170754.1 1405234 D 717522 CDS YP_005170755.1 378771022 11809569 1406043..1406351 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1260 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base deletion splits Rv1260 into 2 parts; putative oxidoreductase 1406351 11809569 BCGMEX_1291 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170755.1 1406043 D 717522 CDS YP_005170756.1 378771023 11809570 complement(1406477..1406926) 1 NC_016804.1 hypothetical protein 1406926 11809570 BCGMEX_1292c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170756.1 1406477 R 717522 CDS YP_005170757.1 378771024 11809571 complement(1406931..1407365) 1 NC_016804.1 Differs from Rv1262c by 1aa, R104P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative HIT-like protein 1407365 11809571 BCGMEX_1293c Mycobacterium bovis BCG str. Mexico putative HIT-like protein YP_005170757.1 1406931 R 717522 CDS YP_005170758.1 378771025 11809572 1407424..1408812 1 NC_016804.1 amidase 1408812 amiB2 11809572 amiB2 Mycobacterium bovis BCG str. Mexico amidase YP_005170758.1 1407424 D 717522 CDS YP_005170759.1 378771026 11809573 1408887..1410080 1 NC_016804.1 Differs from Rv1264 by 1aa, C204R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; adenylate cyclase 1410080 11809573 BCGMEX_1295 Mycobacterium bovis BCG str. Mexico adenylate cyclase YP_005170759.1 1408887 D 717522 CDS YP_005170760.1 378771027 11809574 1410253..1410933 1 NC_016804.1 hypothetical protein 1410933 11809574 BCGMEX_1296 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170760.1 1410253 D 717522 CDS YP_005170761.1 378771028 11809575 complement(1410953..1412743) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, the pknH gene contains several substitutions, transitions and transversions compared to Mycobacterium tuberculosis strain H37Rv. The most significant difference results from a 127 bp to 24 bp substitution that leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (596 aa versus 626 aa). Differs from Mb1297c by 2aa, F374L, I396N in BCG Pasteur and BCG Tokyo; putative transmembrane serine/threonine-protein kinase H 1412743 pknH 11809575 pknH Mycobacterium bovis BCG str. Mexico putative transmembrane serine/threonine-protein kinase H YP_005170761.1 1410953 R 717522 CDS YP_005170762.1 378771029 11809576 complement(1413084..1414250) 1 NC_016804.1 putative transcriptional regulatory protein 1414250 embR 11809576 embR Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170762.1 1413084 R 717522 CDS YP_005170763.1 378771030 11809577 complement(1414561..1415259) 1 NC_016804.1 hypothetical protein 1415259 11809577 BCGMEX_1299c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170763.1 1414561 R 717522 CDS YP_005170764.1 378771031 11809578 complement(1415482..1415856) 1 NC_016804.1 hypothetical protein 1415856 11809578 BCGMEX_1300c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170764.1 1415482 R 717522 CDS YP_005170765.1 378771032 11809579 complement(1415917..1416651) 1 NC_016804.1 Differs from Mb1301c by 1aa, A134T in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 1416651 lprA 11809579 lprA Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170765.1 1415917 R 717522 CDS YP_005170766.1 378771033 11809580 complement(1416864..1417205) 1 NC_016804.1 hypothetical protein 1417205 11809580 BCGMEX_1302c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170766.1 1416864 R 717522 CDS YP_005170767.1 378771034 11809581 complement(1417313..1419208) 1 NC_016804.1 putative drugs-transport transmembrane ATP-binding protein ABC transporter 1419208 11809581 BCGMEX_1303c Mycobacterium bovis BCG str. Mexico putative drugs-transport transmembrane ATP-binding protein ABC transporter YP_005170767.1 1417313 R 717522 CDS YP_005170768.1 378771035 11809582 complement(1419205..1420953) 1 NC_016804.1 putative drugs-transport transmembrane ATP-binding protein ABC transporter 1420953 11809582 BCGMEX_1304c Mycobacterium bovis BCG str. Mexico putative drugs-transport transmembrane ATP-binding protein ABC transporter YP_005170768.1 1419205 R 717522 CDS YP_005170769.1 378771036 11809583 1421100..1421657 1 NC_016804.1 Differs from Rv1274 by 1aa, P168L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 1421657 lprB 11809583 lprB Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170769.1 1421100 D 717522 CDS YP_005170770.1 378771037 11809584 1421654..1422196 1 NC_016804.1 putative lipoprotein 1422196 lprC 11809584 lprC Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170770.1 1421654 D 717522 CDS YP_005170771.1 378771038 11809585 complement(1422341..1422817) 1 NC_016804.1 Differs from Rv1276c by 1aa, S92T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1422817 11809585 BCGMEX_1307c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170771.1 1422341 R 717522 CDS YP_005170772.1 378771039 11809586 1423067..1424320 1 NC_016804.1 hypothetical protein 1424320 11809586 BCGMEX_1308 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170772.1 1423067 D 717522 CDS YP_005170773.1 378771040 11809587 1424317..1426944 1 NC_016804.1 hypothetical protein 1426944 11809587 BCGMEX_1309 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170773.1 1424317 D 717522 CDS YP_005170774.1 378771041 11809588 1426965..1428551 1 NC_016804.1 putative dehydrogenase FAD flavoprotein gmc oxidoreductase 1428551 11809588 BCGMEX_1310 Mycobacterium bovis BCG str. Mexico putative dehydrogenase FAD flavoprotein gmc oxidoreductase YP_005170774.1 1426965 D 717522 CDS YP_005170775.1 378771042 11809589 complement(1428568..1430343) 1 NC_016804.1 putative periplasmic oligopeptide-binding lipoprotein 1430343 oppA 11809589 oppA Mycobacterium bovis BCG str. Mexico putative periplasmic oligopeptide-binding lipoprotein YP_005170775.1 1428568 R 717522 CDS YP_005170776.1 378771043 11809590 complement(1430336..1432174) 1 NC_016804.1 putative oligopeptide-transport integral membrane protein ABC transporter 1432174 oppD 11809590 oppD Mycobacterium bovis BCG str. Mexico putative oligopeptide-transport integral membrane protein ABC transporter YP_005170776.1 1430336 R 717522 CDS YP_005170777.1 378771044 11809591 complement(1432171..1433046) 1 NC_016804.1 putative oligopeptide-transport integral membrane protein ABC transporter 1433046 oppC 11809591 oppC Mycobacterium bovis BCG str. Mexico putative oligopeptide-transport integral membrane protein ABC transporter YP_005170777.1 1432171 R 717522 CDS YP_005170778.1 378771045 11809592 complement(1433043..1434020) 1 NC_016804.1 putative oligopeptide-transport integral membrane protein ABC transporter 1434020 oppB 11809592 oppB Mycobacterium bovis BCG str. Mexico putative oligopeptide-transport integral membrane protein ABC transporter YP_005170778.1 1433043 R 717522 CDS YP_005170779.1 378771046 11809593 1434227..1434718 1 NC_016804.1 beta-carbonic anhydrase 1434718 canA 11809593 canA Mycobacterium bovis BCG str. Mexico beta-carbonic anhydrase YP_005170779.1 1434227 D 717522 CDS YP_005170780.1 378771047 11809594 1434812..1435810 1 NC_016804.1 putative sulfate adenylyltransferase subunit 2 1435810 cysD 11809594 cysD Mycobacterium bovis BCG str. Mexico putative sulfate adenylyltransferase subunit 2 YP_005170780.1 1434812 D 717522 CDS YP_005170781.1 378771048 11809595 1435810..1437654 1 NC_016804.1 Differs from Mb1317 by 1aa, V245L in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Sulfate adenylyltransferase subunit 1 / Adenylylsulfate kinase 1437654 cysN 11809595 cysN Mycobacterium bovis BCG str. Mexico Sulfate adenylyltransferase subunit 1 / Adenylylsulfate kinase YP_005170781.1 1435810 D 717522 CDS YP_005170782.1 378771049 11809596 1437708..1438193 1 NC_016804.1 hypothetical protein 1438193 11809596 BCGMEX_1318 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170782.1 1437708 D 717522 CDS YP_005170783.1 378771050 11809597 1438251..1439468 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a 153 bp deletion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (405 aa versus 456 aa); hypothetical protein 1439468 11809597 BCGMEX_1319 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170783.1 1438251 D 717522 CDS YP_005170784.1 378771051 11809598 1439517..1440149 1 NC_016804.1 hypothetical protein 1440149 11809598 BCGMEX_1320 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170784.1 1439517 D 717522 CDS YP_005170785.1 378771052 11809599 complement(1440288..1441853) 1 NC_016804.1 hypothetical protein 1441853 11809599 BCGMEX_1321c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170785.1 1440288 R 717522 CDS YP_005170786.1 378771053 11809600 1441864..1442178 1 NC_016804.1 hypothetical protein 1442178 11809600 BCGMEX_1322 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170786.1 1441864 D 717522 CDS YP_005170787.1 378771054 11809601 complement(1442305..1442640) 1 NC_016804.1 hypothetical protein 1442640 11809601 BCGMEX_1323c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170787.1 1442305 R 717522 CDS YP_005170788.1 378771055 11809603 1443185..1444837 1 NC_016804.1 arginyl-tRNA synthetase 1444837 argS 11809603 argS Mycobacterium bovis BCG str. Mexico arginyl-tRNA synthetase YP_005170788.1 1443185 D 717522 CDS YP_005170789.1 378771056 11809604 1444834..1446177 1 NC_016804.1 putative diaminopimelate decarboxylase 1446177 lysA 11809604 lysA Mycobacterium bovis BCG str. Mexico putative diaminopimelate decarboxylase YP_005170789.1 1444834 D 717522 CDS YP_005170790.1 378771057 11809605 1446181..1447506 1 NC_016804.1 homoserine dehydrogenase 1447506 thrA 11809605 thrA Mycobacterium bovis BCG str. Mexico homoserine dehydrogenase YP_005170790.1 1446181 D 717522 CDS YP_005170791.1 378771058 11809606 1447503..1448585 1 NC_016804.1 Threonine synthase 1448585 thrC 11809606 thrC Mycobacterium bovis BCG str. Mexico Threonine synthase YP_005170791.1 1447503 D 717522 CDS YP_005170792.1 378771059 11809607 1448803..1449753 1 NC_016804.1 homoserine kinase 1449753 thrB 11809607 thrB Mycobacterium bovis BCG str. Mexico homoserine kinase YP_005170792.1 1448803 D 717522 CDS YP_005170793.1 378771060 11809608 1450010..1451818 1 NC_016804.1 Transcription termination factor 1451818 rho 11809608 rho Mycobacterium bovis BCG str. Mexico Transcription termination factor YP_005170793.1 1450010 D 717522 CDS YP_005170794.1 378771061 11809609 1451969..1452211 1 NC_016804.1 50S ribosomal protein L31 1452211 rpmE 11809609 rpmE Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L31 YP_005170794.1 1451969 D 717522 CDS YP_005170795.1 378771062 11809610 1452301..1453374 1 NC_016804.1 peptide chain release factor 1 1453374 prfA 11809610 prfA Mycobacterium bovis BCG str. Mexico peptide chain release factor 1 YP_005170795.1 1452301 D 717522 CDS YP_005170796.1 378771063 11809611 1453371..1454348 1 NC_016804.1 Differs from Mb1332 by 1aa, G121A, and from Rv1300by 2aa, G121A, C194R in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative HemK protein-like protein 1454348 hemK 11809611 hemK Mycobacterium bovis BCG str. Mexico putative HemK protein-like protein YP_005170796.1 1453371 D 717522 CDS YP_005170797.1 378771064 11809612 1454364..1455017 1 NC_016804.1 Differs from Rv1301 by 1aa, Q196P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; hypothetical protein 1455017 11809612 BCGMEX_1333 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170797.1 1454364 D 717522 CDS YP_005170798.1 378771065 11809613 1455101..1456315 1 NC_016804.1 Differs from Rv1302 by 1aa, G357V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; putative undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase 1456315 rfe 11809613 rfe Mycobacterium bovis BCG str. Mexico putative undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase YP_005170798.1 1455101 D 717522 CDS YP_005170799.1 378771066 11809614 1456572..1457057 1 NC_016804.1 hypothetical protein 1457057 11809614 BCGMEX_1335 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170799.1 1456572 D 717522 CDS YP_005170800.1 378771067 11809615 1457050..1457802 1 NC_016804.1 ATP synthase subunit A 1457802 atpB 11809615 atpB Mycobacterium bovis BCG str. Mexico ATP synthase subunit A YP_005170800.1 1457050 D 717522 CDS YP_005170801.1 378771068 11809616 1457851..1458096 1 NC_016804.1 ATP synthase subunit C 1458096 atpE 11809616 atpE Mycobacterium bovis BCG str. Mexico ATP synthase subunit C YP_005170801.1 1457851 D 717522 CDS YP_005170802.1 378771069 11809617 1458127..1458642 1 NC_016804.1 ATP synthase subunit B 1458642 atpF 11809617 atpF Mycobacterium bovis BCG str. Mexico ATP synthase subunit B YP_005170802.1 1458127 D 717522 CDS YP_005170803.1 378771070 11809618 1458649..1459989 1 NC_016804.1 ATP synthase subunit delta 1459989 atpH 11809618 atpH Mycobacterium bovis BCG str. Mexico ATP synthase subunit delta YP_005170803.1 1458649 D 717522 CDS YP_005170804.1 378771071 11809619 1460034..1461683 1 NC_016804.1 ATP synthase subunit alpha 1461683 atpA 11809619 atpA Mycobacterium bovis BCG str. Mexico ATP synthase subunit alpha YP_005170804.1 1460034 D 717522 CDS YP_005170805.1 378771072 11809620 1461690..1462607 1 NC_016804.1 ATP synthase subunit gamma 1462607 atpG 11809620 atpG Mycobacterium bovis BCG str. Mexico ATP synthase subunit gamma YP_005170805.1 1461690 D 717522 CDS YP_005170806.1 378771073 11809621 1462647..1464107 1 NC_016804.1 ATP synthase subunir beta 1464107 atpD 11809621 atpD Mycobacterium bovis BCG str. Mexico ATP synthase subunir beta YP_005170806.1 1462647 D 717522 CDS YP_005170807.1 378771074 11809622 1464121..1464486 1 NC_016804.1 ATP synthase subunit epsilon 1464486 atpC 11809622 atpC Mycobacterium bovis BCG str. Mexico ATP synthase subunit epsilon YP_005170807.1 1464121 D 717522 CDS YP_005170808.1 378771075 11809623 1464494..1464928 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a 2 bp deletion at the 3' end leads to a slightly shorter product compared to Mycobacterium tuberculosis strain H37Rv (144 aa versus 147 aa). Also differs from Rv1312 by 1aa, V3A in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1464928 11809623 BCGMEX_1344 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170808.1 1464494 D 717522 CDS YP_005170809.1 378771076 11809624 complement(1464975..1465706) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1313c exists as a single gene. In Mycobacterium bovis and Mycobacterium bovis BCG Pasteur and BCG Mexico, a frameshift due to a 12 bp to 1bp substitution splits Rv1313c into 2 parts. Equivalent to Rv1313c (IS1557) in BCG Tokyo.; putative transposase (second part) 1465706 11809624 BCGMEX_1345c Mycobacterium bovis BCG str. Mexico putative transposase (second part) YP_005170809.1 1464975 R 717522 CDS YP_005170810.1 378771077 11809625 complement(1465681..1466298) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1313c exists as a single gene. In Mycobacterium bovis and Mycobacterium bovis BCG Pasteur and BCG Mexico, a frameshift due to a 12 bp to 1 bp substitution splits Rv1313c into 2 parts; putative transposase (first part) 1466298 11809625 BCGMEX_1346c Mycobacterium bovis BCG str. Mexico putative transposase (first part) YP_005170810.1 1465681 R 717522 CDS YP_005170811.1 378771078 11809626 complement(1466464..1467045) 1 NC_016804.1 hypothetical protein 1467045 11809626 BCGMEX_1347c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170811.1 1466464 R 717522 CDS YP_005170812.1 378771079 11809627 1467114..1468370 1 NC_016804.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1468370 murA 11809627 murA Mycobacterium bovis BCG str. Mexico UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_005170812.1 1467114 D 717522 CDS YP_005170813.1 378771080 11809631 complement(1473927..1474424) 1 NC_016804.1 putative methylated-DNA--protein-cysteine methyltransferase 1474424 ogt 11809631 ogt Mycobacterium bovis BCG str. Mexico putative methylated-DNA--protein-cysteine methyltransferase YP_005170813.1 1473927 R 717522 CDS YP_005170814.1 378771081 11809632 complement(1474421..1475911) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium tuberculosis strain H37Rv, alkA exists as a single gene. In Mycobacterium bovis, a single base transition introduces a premature stop codon that splits alkA into 2 parts, alkAa and alkAb; putative ada regulatory protein 1475911 alkA 11809632 alkA Mycobacterium bovis BCG str. Mexico putative ada regulatory protein YP_005170814.1 1474421 R 717522 CDS YP_005170815.1 378771082 11809633 complement(1475992..1477617) 1 NC_016804.1 putative adenylate cyclase 1477617 11809633 BCGMEX_1351c Mycobacterium bovis BCG str. Mexico putative adenylate cyclase YP_005170815.1 1475992 R 717522 CDS YP_005170816.1 378771083 11809634 complement(1477687..1479294) 1 NC_016804.1 putative adenylate cyclase 1479294 11809634 BCGMEX_1352c Mycobacterium bovis BCG str. Mexico putative adenylate cyclase YP_005170816.1 1477687 R 717522 CDS YP_005170817.1 378771084 11809635 complement(1479307..1481010) 1 NC_016804.1 Differs from Rv1320c by 1aa, A531T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative adenylate cyclase 1481010 11809635 BCGMEX_1353c Mycobacterium bovis BCG str. Mexico putative adenylate cyclase YP_005170817.1 1479307 R 717522 CDS YP_005170818.1 378771085 11809636 1481072..1481752 1 NC_016804.1 Differs from Rv1321 by 1aa, R144S in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1481752 11809636 BCGMEX_1354 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170818.1 1481072 D 717522 CDS YP_005170819.1 378771086 11809637 1481775..1482071 1 NC_016804.1 hypothetical protein 1482071 11809637 BCGMEX_1355 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170819.1 1481775 D 717522 CDS YP_005170820.1 378771087 11809638 complement(1482106..1482564) 1 NC_016804.1 hypothetical protein 1482564 11809638 BCGMEX_1356c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170820.1 1482106 R 717522 CDS YP_005170821.1 378771088 11809639 1482655..1483824 1 NC_016804.1 putative acetyl-CoA acetyltransferase 1483824 fadA4 11809639 fadA4 Mycobacterium bovis BCG str. Mexico putative acetyl-CoA acetyltransferase YP_005170821.1 1482655 D 717522 CDS YP_005170822.1 378771089 11809640 1483954..1484868 1 NC_016804.1 putative thioredoxin 1484868 11809640 BCGMEX_1358 Mycobacterium bovis BCG str. Mexico putative thioredoxin YP_005170822.1 1483954 D 717522 CDS YP_005170823.1 378771090 11809641 complement(1484947..1486758) 1 NC_016804.1 Differs from Rv1325c by 1aa, A320T in Mycobacterium bovis BCG Pasteur and Mexico. In BCG Tokyo differs, there are deleted in Mycobacterium bovis BCG Tokyo.; PE-PGRS family protein 1486758 PE_PGRS24 11809641 PE_PGRS24 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170823.1 1484947 R 717522 CDS YP_005170824.1 378771091 11809642 complement(1486910..1489105) 1 NC_016804.1 Differs from Rv1326c by 3aa, G40D, S468P, P470S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; glycogen branching enzyme 1489105 glgB 11809642 glgB Mycobacterium bovis BCG str. Mexico glycogen branching enzyme YP_005170824.1 1486910 R 717522 CDS YP_005170825.1 378771092 11809643 complement(1489113..1491218) 1 NC_016804.1 putative glucanase 1491218 glgE 11809643 glgE Mycobacterium bovis BCG str. Mexico putative glucanase YP_005170825.1 1489113 R 717522 CDS YP_005170826.1 378771093 11809644 1491357..1493948 1 NC_016804.1 Differs from Rv1328 by 3aa, G532D, F576V, S801A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative glycogen phosphorylase 1493948 glgP 11809644 glgP Mycobacterium bovis BCG str. Mexico putative glycogen phosphorylase YP_005170826.1 1491357 D 717522 CDS YP_005170827.1 378771094 11809645 complement(1493988..1495982) 1 NC_016804.1 putative ATP-dependent helicase DinG-like protein 1495982 dinG 11809645 dinG Mycobacterium bovis BCG str. Mexico putative ATP-dependent helicase DinG-like protein YP_005170827.1 1493988 R 717522 CDS YP_005170828.1 378771095 11809646 complement(1496006..1497352) 1 NC_016804.1 Differs from Rv1330c by 1aa, A429D and from Mb1365c by 1aa, E358K in BCG Pasteur, BCG Tokyo and BCG Mexico; nicotinate phosphoribosyltransferase 1497352 11809646 BCGMEX_1364c Mycobacterium bovis BCG str. Mexico nicotinate phosphoribosyltransferase YP_005170828.1 1496006 R 717522 CDS YP_005170829.1 378771096 11809647 1497454..1497759 1 NC_016804.1 ATP-dependent Clp protease adaptor protein 1497759 clpS 11809647 clpS Mycobacterium bovis BCG str. Mexico ATP-dependent Clp protease adaptor protein YP_005170829.1 1497454 D 717522 CDS YP_005170830.1 378771097 11809648 1497719..1498375 1 NC_016804.1 putative transcriptional regulatory protein 1498375 11809648 BCGMEX_1366 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170830.1 1497719 D 717522 CDS YP_005170831.1 378771098 11809649 1498392..1499426 1 NC_016804.1 putative hydrolase 1499426 11809649 BCGMEX_1367 Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005170831.1 1498392 D 717522 CDS YP_005170832.1 378771099 11809650 1499461..1499874 1 NC_016804.1 hypothetical protein 1499874 11809650 BCGMEX_1368 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170832.1 1499461 D 717522 CDS YP_005170833.1 378771100 11809651 1499896..1500177 1 NC_016804.1 9.5 kDa culture filtrate antigen cfp10A 1500177 11809651 BCGMEX_1369 Mycobacterium bovis BCG str. Mexico 9.5 kDa culture filtrate antigen cfp10A YP_005170833.1 1499896 D 717522 CDS YP_005170834.1 378771101 11809652 1500187..1501158 1 NC_016804.1 putative cysteine synthase B 1501158 cysM 11809652 cysM Mycobacterium bovis BCG str. Mexico putative cysteine synthase B YP_005170834.1 1500187 D 717522 CDS YP_005170835.1 378771102 11809653 1501149..1501871 1 NC_016804.1 putative integral membrane protein 1501871 11809653 BCGMEX_1371 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170835.1 1501149 D 717522 CDS YP_005170836.1 378771103 11809654 1501868..1502683 1 NC_016804.1 Differs from Rv1338 and Mb1373 by 1aa, L154R in BCG Pasteur, BCG Tokyo and BCG Mexico; glutamate racemase 1502683 murI 11809654 murI Mycobacterium bovis BCG str. Mexico glutamate racemase YP_005170836.1 1501868 D 717522 CDS YP_005170837.1 378771104 11809655 1502710..1503531 1 NC_016804.1 hypothetical protein 1503531 11809655 BCGMEX_1373 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170837.1 1502710 D 717522 CDS YP_005170838.1 378771105 11809656 1503548..1504327 1 NC_016804.1 Differs from Mb1375 by 1aa, G97S in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasrteur, BCG Tokyo and BCG Mexico; ribonuclease 1504327 rph 11809656 rph Mycobacterium bovis BCG str. Mexico ribonuclease YP_005170838.1 1503548 D 717522 CDS YP_005170839.1 378771106 11809657 1504366..1504980 1 NC_016804.1 putative deoxyribonucleotide triphosphate pyrophosphatase 1504980 11809657 BCGMEX_1375 Mycobacterium bovis BCG str. Mexico putative deoxyribonucleotide triphosphate pyrophosphatase YP_005170839.1 1504366 D 717522 CDS YP_005170840.1 378771107 11809658 complement(1504977..1505339) 1 NC_016804.1 hypothetical protein 1505339 11809658 BCGMEX_1376c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170840.1 1504977 R 717522 CDS YP_005170841.1 378771108 11809659 complement(1505336..1505716) 1 NC_016804.1 Differs from Rv1343c by 1aa, A81E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 1505716 lprD 11809659 lprD Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170841.1 1505336 R 717522 CDS YP_005170842.1 378771109 11809660 1505761..1506081 1 NC_016804.1 acyl carrier protein 1506081 11809660 BCGMEX_1378 Mycobacterium bovis BCG str. Mexico acyl carrier protein YP_005170842.1 1505761 D 717522 CDS YP_005170843.1 378771110 11809661 1506074..1507639 1 NC_016804.1 acyl-CoA synthetase 1507639 fadD33 11809661 fadD33 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005170843.1 1506074 D 717522 CDS YP_005170844.1 378771111 11809662 1507639..1508799 1 NC_016804.1 putative acyl-CoA dehydrogenase 1508799 fadE14 11809662 fadE14 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005170844.1 1507639 D 717522 CDS YP_005170845.1 378771112 11809663 complement(1508766..1509398) 1 NC_016804.1 hypothetical protein 1509398 11809663 BCGMEX_1381c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170845.1 1508766 R 717522 CDS YP_005170846.1 378771113 11809665 1509840..1512419 1 NC_016804.1 putative drugs-transport transmembrane ATP-binding protein ABC transporter 1512419 11809665 BCGMEX_1382 Mycobacterium bovis BCG str. Mexico putative drugs-transport transmembrane ATP-binding protein ABC transporter YP_005170846.1 1509840 D 717522 CDS YP_005170847.1 378771114 11809666 1512416..1514155 1 NC_016804.1 putative drugs-transport transmembrane ATP-binding protein ABC transporter 1514155 11809666 BCGMEX_1383 Mycobacterium bovis BCG str. Mexico putative drugs-transport transmembrane ATP-binding protein ABC transporter YP_005170847.1 1512416 D 717522 CDS YP_005170848.1 378771115 11809667 1514284..1515027 1 NC_016804.1 putative 3-oxoacyl-[acyl-carrier protein] reductase 1515027 fabG 11809667 fabG Mycobacterium bovis BCG str. Mexico putative 3-oxoacyl-[acyl-carrier protein] reductase YP_005170848.1 1514284 D 717522 CDS YP_005170849.1 378771116 11809668 1515024..1515353 1 NC_016804.1 hypothetical protein 1515353 11809668 BCGMEX_1385 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170849.1 1515024 D 717522 CDS YP_005170850.1 378771117 11809669 1515556..1515927 1 NC_016804.1 hypothetical protein 1515927 11809669 BCGMEX_1386 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170850.1 1515556 D 717522 CDS YP_005170851.1 378771118 11809670 complement(1515993..1516778) 1 NC_016804.1 putative transcriptional regulatory protein 1516778 11809670 BCGMEX_1387c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170851.1 1515993 R 717522 CDS YP_005170852.1 378771119 11809671 complement(1516798..1518669) 1 NC_016804.1 hypothetical protein 1518669 11809671 BCGMEX_1388c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170852.1 1516798 R 717522 CDS YP_005170853.1 378771120 11809672 complement(1518678..1520825) 1 NC_016804.1 Differs from Rv1355c by 1aa (P81L) in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative molybdopterin biosynthesis protein 1520825 moeY 11809672 moeY Mycobacterium bovis BCG str. Mexico putative molybdopterin biosynthesis protein YP_005170853.1 1518678 R 717522 CDS YP_005170854.1 378771121 11809673 complement(1520822..1521613) 1 NC_016804.1 hypothetical protein 1521613 11809673 BCGMEX_1390c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170854.1 1520822 R 717522 CDS YP_005170855.1 378771122 11809674 complement(1522086..1523009) 1 NC_016804.1 Differs from Rv1357c and Mb1392c by 1aa, S276T in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1523009 11809674 BCGMEX_1391c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170855.1 1522086 R 717522 CDS YP_005170856.1 378771123 11809675 1523405..1526884 1 NC_016804.1 Differs from Rv1358 by 1aa A442D, and from Mb1393 by 1aa, G31V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 1526884 11809675 BCGMEX_1392 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170856.1 1523405 D 717522 CDS YP_005170857.1 378771124 11809676 1526966..1527718 1 NC_016804.1 Differs from Mb1394 by 1aa, G187R in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 1527718 11809676 BCGMEX_1393 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170857.1 1526966 D 717522 CDS YP_005170858.1 378771125 11809677 1528141..1529163 1 NC_016804.1 putative oxidoreductase 1529163 11809677 BCGMEX_1394 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005170858.1 1528141 D 717522 CDS YP_005170859.1 378771126 11809678 complement(1529236..1530426) 1 NC_016804.1 Differs from Rv1361c by 3aa, Q30K, V55T, P325Q in BCG Pasteur, BCG Tokyo and BCG Mexico, and more extensively from Mb1396c due to several substitutions, transitions and transversions between codons 158-260; PPE family protein 1530426 PPE19 11809678 PPE19 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170859.1 1529236 R 717522 CDS YP_005170860.1 378771127 11809679 complement(1530741..1531403) 1 NC_016804.1 Differs from Rv1362c by 1aa, G103V Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1531403 11809679 BCGMEX_1396c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170860.1 1530741 R 717522 CDS YP_005170861.1 378771128 11809680 complement(1531400..1532185) 1 NC_016804.1 Differs from Mb1398c by 1aa, T155N in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1532185 11809680 BCGMEX_1397c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170861.1 1531400 R 717522 CDS YP_005170862.1 378771129 11809681 complement(1532476..1534437) 1 NC_016804.1 Differs from Rv1364c by 2aa, T236A, E465A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1534437 11809681 BCGMEX_1398c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170862.1 1532476 R 717522 CDS YP_005170863.1 378771130 11809682 complement(1534576..1534962) 1 NC_016804.1 Differs from Rv1365c by 1aa, K82E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; anti-sigma factor antagonist 1534962 11809682 BCGMEX_1399c Mycobacterium bovis BCG str. Mexico anti-sigma factor antagonist YP_005170863.1 1534576 R 717522 CDS YP_005170864.1 378771131 11809683 1535183..1536004 1 NC_016804.1 hypothetical protein 1536004 11809683 BCGMEX_1400 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170864.1 1535183 D 717522 CDS YP_005170865.1 378771132 11809684 complement(1536305..1537438) 1 NC_016804.1 Differs from Rv1367c by 1aa, V169I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1537438 11809684 BCGMEX_1401c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170865.1 1536305 R 717522 CDS YP_005170866.1 378771133 11809685 1537813..1538598 1 NC_016804.1 putative lipoprotein 1538598 lprF 11809685 lprF Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170866.1 1537813 D 717522 CDS YP_005170867.1 378771134 11809686 1538794..1539747 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1371 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a frameshift due to a single base insertion splits Rv1371 into 2 parts, with the latter being the more likely product; hypothetical protein 1539747 11809686 BCGMEX_1403 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170867.1 1538794 D 717522 CDS YP_005170868.1 378771135 11809687 1539269..1540264 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1371 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion splits Rv1371 into 2 parts, with the latter being the more likely product. Differs from both Mb1405 and Rv1371 by 1aa, V210I in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1540264 11809687 BCGMEX_1404 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170868.1 1539269 D 717522 CDS YP_005170869.1 378771136 11809688 1540261..1541442 1 NC_016804.1 Differs from Rv1372 and Mb1406 by 2aa, N75K, A101T in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1541442 11809688 BCGMEX_1405 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170869.1 1540261 D 717522 CDS YP_005170870.1 378771137 11809689 1541448..1542431 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1373 exists as a single gene as is the case in Mycobacterium bovis BCG Pasteur and BCG Mexico. In Mycobacterium bovis, a frameshift due to a single base insertion splits Rv1373 into 2 parts, Mb1407 and Mb1408. Differs from Rv1373 by 2aa, additional P, P155, and L232P. In Mycobacterium bovis BCG Tokyo, a frameshift due to two base insertions splits Rv1373 into 2 parts (182 aa, 155 aa).; glycolipid sulfotransferase 1542431 11809689 BCGMEX_1406 Mycobacterium bovis BCG str. Mexico glycolipid sulfotransferase YP_005170870.1 1541448 D 717522 CDS YP_005170871.1 378771138 11809690 complement(1542511..1542969) 1 NC_016804.1 Differs from Rv1374c by 1aa, A136T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1542969 11809690 BCGMEX_1407c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170871.1 1542511 R 717522 CDS YP_005170872.1 378771139 11809691 1543271..1544590 1 NC_016804.1 Differs from Rv1375 by 1aa, R86G, and from Mb1410by 1aa, R322P in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1544590 11809691 BCGMEX_1408 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170872.1 1543271 D 717522 CDS YP_005170873.1 378771140 11809692 1544587..1546080 1 NC_016804.1 Differs from Rv1376 by 1aa, P236R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1546080 11809692 BCGMEX_1409 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170873.1 1544587 D 717522 CDS YP_005170874.1 378771141 11809693 complement(1546018..1546656) 1 NC_016804.1 putative transferase 1546656 11809693 BCGMEX_1410c Mycobacterium bovis BCG str. Mexico putative transferase YP_005170874.1 1546018 R 717522 CDS YP_005170875.1 378771142 11809694 complement(1546667..1548094) 1 NC_016804.1 Differs from Rv1378c by 1aa, W37R, and from Mb1413c by 1aa, R9H in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1548094 11809694 BCGMEX_1411c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170875.1 1546667 R 717522 CDS YP_005170876.1 378771143 11809695 1548093..1548674 1 NC_016804.1 Pyrimidine regulatory protein 1548674 pyrR 11809695 pyrR Mycobacterium bovis BCG str. Mexico Pyrimidine regulatory protein YP_005170876.1 1548093 D 717522 CDS YP_005170877.1 378771144 11809696 1548671..1549630 1 NC_016804.1 aspartate carbamoyltransferase catalytic subunit 1549630 pyrB 11809696 pyrB Mycobacterium bovis BCG str. Mexico aspartate carbamoyltransferase catalytic subunit YP_005170877.1 1548671 D 717522 CDS YP_005170878.1 378771145 11809697 1549627..1550919 1 NC_016804.1 Differs from Rv1381 by 1aa, F189V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; dihydroorotase 1550919 pyrC 11809697 pyrC Mycobacterium bovis BCG str. Mexico dihydroorotase YP_005170878.1 1549627 D 717522 CDS YP_005170879.1 378771146 11809698 1550916..1551413 1 NC_016804.1 putative export or membrane protein 1551413 11809698 BCGMEX_1415 Mycobacterium bovis BCG str. Mexico putative export or membrane protein YP_005170879.1 1550916 D 717522 CDS YP_005170880.1 378771147 11809699 1551410..1552540 1 NC_016804.1 Differs from Rv1383 by 1aa, G118A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative carbamoyl-phosphate synthase small chain 1552540 carA 11809699 carA Mycobacterium bovis BCG str. Mexico putative carbamoyl-phosphate synthase small chain YP_005170880.1 1551410 D 717522 CDS YP_005170881.1 378771148 11809700 1552540..1555887 1 NC_016804.1 Differs from Rv1384 by 1aa, E821A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; carbamoyl-phosphate synthase large chain 1555887 carB 11809700 carB Mycobacterium bovis BCG str. Mexico carbamoyl-phosphate synthase large chain YP_005170881.1 1552540 D 717522 CDS YP_005170882.1 378771149 11809701 1555884..1556708 1 NC_016804.1 Orotidine 5'-phosphate decarboxylase 1556708 pyrF 11809701 pyrF Mycobacterium bovis BCG str. Mexico Orotidine 5'-phosphate decarboxylase YP_005170882.1 1555884 D 717522 CDS YP_005170883.1 378771150 11809702 1556903..1557211 1 NC_016804.1 PE family protein 1557211 PE15 11809702 PE15 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170883.1 1556903 D 717522 CDS YP_005170884.1 378771151 11809703 1557208..1558827 1 NC_016804.1 Differs from Rv1387 by 1aa, A94V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 1558827 PPE20 11809703 PPE20 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005170884.1 1557208 D 717522 CDS YP_005170885.1 378771152 11809704 1559133..1559705 1 NC_016804.1 putative integration host factor 1559705 mihF 11809704 mihF Mycobacterium bovis BCG str. Mexico putative integration host factor YP_005170885.1 1559133 D 717522 CDS YP_005170886.1 378771153 11809705 1559840..1560466 1 NC_016804.1 guanylate kinase 1560466 gmk 11809705 gmk Mycobacterium bovis BCG str. Mexico guanylate kinase YP_005170886.1 1559840 D 717522 CDS YP_005170887.1 378771154 11809706 1560532..1560864 1 NC_016804.1 DNA-directed RNA polymerase subunit omega 1560864 rpoZ 11809706 rpoZ Mycobacterium bovis BCG str. Mexico DNA-directed RNA polymerase subunit omega YP_005170887.1 1560532 D 717522 CDS YP_005170888.1 378771155 11809707 1560880..1562136 1 NC_016804.1 putative bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1562136 dfp 11809707 dfp Mycobacterium bovis BCG str. Mexico putative bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_005170888.1 1560880 D 717522 CDS YP_005170889.1 378771156 11809708 1562264..1563475 1 NC_016804.1 Differs from Rv1392 by 1aa, Q195R, and from Mb1427 by 2aa, T60A Q195R in BCG Pasteur, BCG Tokyo and BCG Mexico; S-adenosylmethionine synthetase 1563475 metK 11809708 metK Mycobacterium bovis BCG str. Mexico S-adenosylmethionine synthetase YP_005170889.1 1562264 D 717522 CDS YP_005170890.1 378771157 11809709 complement(1563548..1565026) 1 NC_016804.1 putative monooxygenase 1565026 11809709 BCGMEX_1426c Mycobacterium bovis BCG str. Mexico putative monooxygenase YP_005170890.1 1563548 R 717522 CDS YP_005170891.1 378771158 11809710 complement(1565023..1566408) 1 NC_016804.1 Differs from Rv1394c by 1aa, L135R in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytochrome P450 132 1566408 cyp132 11809710 cyp132 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 132 YP_005170891.1 1565023 R 717522 CDS YP_005170892.1 378771159 11809711 1566486..1567520 1 NC_016804.1 putative transcriptional regulator 1567520 11809711 BCGMEX_1428 Mycobacterium bovis BCG str. Mexico putative transcriptional regulator YP_005170892.1 1566486 D 717522 CDS YP_005170893.1 378771160 11809712 complement(1567566..1568924) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a 372 bp deletion leads to a shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (452 aa versus 576 aa). Differs from Rv1396c by 2 aa, S66R, H300R in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 1568924 PE_PGRS25 11809712 PE_PGRS25 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170893.1 1567566 R 717522 CDS YP_005170894.1 378771161 11809713 complement(1569179..1569580) 1 NC_016804.1 Differs from Rv1397c by 1aa, G103D in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1569580 11809713 BCGMEX_1430c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170894.1 1569179 R 717522 CDS YP_005170895.1 378771162 11809714 complement(1569577..1569834) 1 NC_016804.1 hypothetical protein 1569834 11809714 BCGMEX_1431c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170895.1 1569577 R 717522 CDS YP_005170896.1 378771163 11809715 complement(1569917..1570876) 1 NC_016804.1 Differs from Rv1399c and Mb1434c by 1aa, A46P in BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipase 1570876 lipH 11809715 lipH Mycobacterium bovis BCG str. Mexico putative lipase YP_005170896.1 1569917 R 717522 CDS YP_005170897.1 378771164 11809716 complement(1570901..1571863) 1 NC_016804.1 putative lipase 1571863 lipI 11809716 lipI Mycobacterium bovis BCG str. Mexico putative lipase YP_005170897.1 1570901 R 717522 CDS YP_005170898.1 378771165 11809717 1571997..1572599 1 NC_016804.1 hypothetical protein 1572599 11809717 BCGMEX_1434 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170898.1 1571997 D 717522 CDS YP_005170899.1 378771166 11809718 1572680..1574647 1 NC_016804.1 primosome assembly protein 1574647 priA 11809718 priA Mycobacterium bovis BCG str. Mexico primosome assembly protein YP_005170899.1 1572680 D 717522 CDS YP_005170900.1 378771167 11809719 complement(1574665..1575489) 1 NC_016804.1 putative methyltransferase 1575489 11809719 BCGMEX_1436c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005170900.1 1574665 R 717522 CDS YP_005170901.1 378771168 11809720 1575658..1576140 1 NC_016804.1 putative transcriptional regulatory protein 1576140 11809720 BCGMEX_1437 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170901.1 1575658 D 717522 CDS YP_005170902.1 378771169 11809721 complement(1576212..1577036) 1 NC_016804.1 putative methyltransferase 1577036 11809721 BCGMEX_1438c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005170902.1 1576212 R 717522 CDS YP_005170903.1 378771170 11809722 1577233..1578171 1 NC_016804.1 methionyl-tRNA formyltransferase 1578171 fmt 11809722 fmt Mycobacterium bovis BCG str. Mexico methionyl-tRNA formyltransferase YP_005170903.1 1577233 D 717522 CDS YP_005170904.1 378771171 11809723 1578168..1579541 1 NC_016804.1 Differs from Rv1407 by 1aa, L427I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative fmu protein 1579541 fmu 11809723 fmu Mycobacterium bovis BCG str. Mexico putative fmu protein YP_005170904.1 1578168 D 717522 CDS YP_005170905.1 378771172 11809724 1579566..1580264 1 NC_016804.1 ribulose-phosphate 3-epimerase 1580264 rpe 11809724 rpe Mycobacterium bovis BCG str. Mexico ribulose-phosphate 3-epimerase YP_005170905.1 1579566 D 717522 CDS YP_005170906.1 378771173 11809725 1580261..1581280 1 NC_016804.1 Differs from Rv1409 by 2aa, N30K, T71A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; diaminohydroxyphosphoribosylaminopyrimidine deaminase, 5-amino-6-(5-phosphoribosylamino) uracil reductase; putative riboflavin biosynthesis protein 1581280 ribG 11809725 ribG Mycobacterium bovis BCG str. Mexico putative riboflavin biosynthesis protein YP_005170906.1 1580261 D 717522 CDS YP_005170907.1 378771174 11809726 complement(1581277..1582833) 1 NC_016804.1 aminoglycosides/tetracycline-transport integral membrane protein 1582833 11809726 BCGMEX_1443c Mycobacterium bovis BCG str. Mexico aminoglycosides/tetracycline-transport integral membrane protein YP_005170907.1 1581277 R 717522 CDS YP_005170908.1 378771175 11809727 complement(1582839..1583549) 1 NC_016804.1 putative lipoprotein 1583549 lprG 11809727 lprG Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170908.1 1582839 R 717522 CDS YP_005170909.1 378771176 11809728 1583634..1584239 1 NC_016804.1 riboflavin synthase subunit alpha 1584239 ribC 11809728 ribC Mycobacterium bovis BCG str. Mexico riboflavin synthase subunit alpha YP_005170909.1 1583634 D 717522 CDS YP_005170910.1 378771177 11809729 1584453..1584968 1 NC_016804.1 hypothetical protein 1584968 11809729 BCGMEX_1446 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170910.1 1584453 D 717522 CDS YP_005170911.1 378771178 11809730 1584958..1585359 1 NC_016804.1 hypothetical protein 1585359 11809730 BCGMEX_1447 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170911.1 1584958 D 717522 CDS YP_005170912.1 378771179 11809731 1585464..1586741 1 NC_016804.1 GTP cyclohydrolase II protein; 3,4-dihydroxy-2-butanone 4-phosphate synthase 1586741 ribA2 11809731 ribA2 Mycobacterium bovis BCG str. Mexico 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_005170912.1 1585464 D 717522 CDS YP_005170913.1 378771180 11809732 1586756..1587220 1 NC_016804.1 riboflavin synthase subunit beta 1587220 ribH 11809732 ribH Mycobacterium bovis BCG str. Mexico riboflavin synthase subunit beta YP_005170913.1 1586756 D 717522 CDS YP_005170914.1 378771181 11809733 1587217..1587681 1 NC_016804.1 hypothetical protein 1587681 11809733 BCGMEX_1450 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170914.1 1587217 D 717522 CDS YP_005170915.1 378771182 11809734 1587706..1588392 1 NC_016804.1 putative lipoprotein 1588392 lprH 11809734 lprH Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005170915.1 1587706 D 717522 CDS YP_005170916.1 378771183 11809735 1588572..1589045 1 NC_016804.1 hypothetical protein 1589045 11809735 BCGMEX_1452 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170916.1 1588572 D 717522 CDS YP_005170917.1 378771184 11809736 1589109..1591049 1 NC_016804.1 excinuclease ABC subunit C 1591049 uvrC 11809736 uvrC Mycobacterium bovis BCG str. Mexico excinuclease ABC subunit C YP_005170917.1 1589109 D 717522 CDS YP_005170918.1 378771185 11809737 1591046..1591951 1 NC_016804.1 nucleotide-binding protein 1591951 11809737 BCGMEX_1454 Mycobacterium bovis BCG str. Mexico nucleotide-binding protein YP_005170918.1 1591046 D 717522 CDS YP_005170919.1 378771186 11809738 1591948..1592976 1 NC_016804.1 Differs from Mb1457 by 1aa, A86V in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1592976 11809738 BCGMEX_1455 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170919.1 1591948 D 717522 CDS YP_005170920.1 378771187 11809739 1592973..1593950 1 NC_016804.1 putative transcriptional regulatory protein 1593950 whiA 11809739 whiA Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170920.1 1592973 D 717522 CDS YP_005170921.1 378771188 11809740 complement(1593960..1594721) 1 NC_016804.1 hypothetical protein 1594721 11809740 BCGMEX_1457c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170921.1 1593960 R 717522 CDS YP_005170922.1 378771189 11809741 1594725..1596104 1 NC_016804.1 Differs from Rv1425 by 1aa, L343P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1596104 11809741 BCGMEX_1458 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170922.1 1594725 D 717522 CDS YP_005170923.1 378771190 11809742 complement(1596126..1597388) 1 NC_016804.1 putative esterase 1597388 lipO 11809742 lipO Mycobacterium bovis BCG str. Mexico putative esterase YP_005170923.1 1596126 R 717522 CDS YP_005170924.1 378771191 11809743 complement(1597388..1598995) 1 NC_016804.1 acyl-CoA synthetase 1598995 fadD12 11809743 fadD12 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005170924.1 1597388 R 717522 CDS YP_005170925.1 378771192 11809744 complement(1598999..1599826) 1 NC_016804.1 hypothetical protein 1599826 11809744 BCGMEX_1461c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170925.1 1598999 R 717522 CDS YP_005170926.1 378771193 11809745 1599945..1601213 1 NC_016804.1 hypothetical protein 1601213 11809745 BCGMEX_1462 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170926.1 1599945 D 717522 CDS YP_005170927.1 378771194 11809746 1601453..1603039 1 NC_016804.1 PE family protein 1603039 PE16 11809746 PE16 Mycobacterium bovis BCG str. Mexico PE family protein YP_005170927.1 1601453 D 717522 CDS YP_005170928.1 378771195 11809747 1603150..1604919 1 NC_016804.1 hypothetical protein 1604919 11809747 BCGMEX_1464 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170928.1 1603150 D 717522 CDS YP_005170929.1 378771196 11809748 1604916..1606337 1 NC_016804.1 putative dehydrogenase 1606337 11809748 BCGMEX_1465 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005170929.1 1604916 D 717522 CDS YP_005170930.1 378771197 11809749 1606501..1607322 1 NC_016804.1 Differs from Rv1433 and Mb1468 at C-terminal end due to 1bp deletion in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1607322 11809749 BCGMEX_1466 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170930.1 1606501 D 717522 CDS YP_005170931.1 378771198 11809750 1607322..1607459 1 NC_016804.1 hypothetical protein 1607459 11809750 BCGMEX_1467 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170931.1 1607322 D 717522 CDS YP_005170932.1 378771199 11809751 complement(1607408..1608037) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, an in-frame insertion of 21 bp leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (209 aa versus 202 aa). Differs from Rv1435c by 1aa, T67A in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; Proline, Glycine, Valine-rich secreted protein 1608037 11809751 BCGMEX_1468c Mycobacterium bovis BCG str. Mexico Proline, Glycine, Valine-rich secreted protein YP_005170932.1 1607408 R 717522 CDS YP_005170933.1 378771200 11809752 1608394..1609413 1 NC_016804.1 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase 1609413 gap 11809752 gap Mycobacterium bovis BCG str. Mexico NAD-dependent glyceraldehyde-3-phosphate dehydrogenase YP_005170933.1 1608394 D 717522 CDS YP_005170934.1 378771201 11809753 1609416..1610654 1 NC_016804.1 phosphoglycerate kinase 1610654 pgk 11809753 pgk Mycobacterium bovis BCG str. Mexico phosphoglycerate kinase YP_005170934.1 1609416 D 717522 CDS YP_005170935.1 378771202 11809754 1610651..1611436 1 NC_016804.1 Differs from Rv1438 and Mb1473 by 1aa, T169I in BCG Pasteur, BCG Tokyo and BCG Mexico; triosephosphate isomerase 1611436 tpiA 11809754 tpiA Mycobacterium bovis BCG str. Mexico triosephosphate isomerase YP_005170935.1 1610651 D 717522 CDS YP_005170936.1 378771203 11809755 complement(1612048..1612473) 1 NC_016804.1 hypothetical protein 1612473 11809755 BCGMEX_1472c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170936.1 1612048 R 717522 CDS YP_005170937.1 378771204 11809756 1612924..1613157 1 NC_016804.1 preprotein translocase subunit 1613157 secG 11809756 secG Mycobacterium bovis BCG str. Mexico preprotein translocase subunit YP_005170937.1 1612924 D 717522 CDS YP_005170938.1 378771205 11809757 complement(1613296..1614771) 1 NC_016804.1 Differs from Rv1441c by 1aa G236D and from Mb1476c by 1aa T354N in BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 1614771 PE_PGRS26 11809757 PE_PGRS26 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170938.1 1613296 R 717522 CDS YP_005170939.1 378771206 11809758 1614878..1617178 1 NC_016804.1 putative biotin sulfoxide reductase 1617178 bisC 11809758 bisC Mycobacterium bovis BCG str. Mexico putative biotin sulfoxide reductase YP_005170939.1 1614878 D 717522 CDS YP_005170940.1 378771207 11809759 complement(1617294..1617779) 1 NC_016804.1 hypothetical protein 1617779 11809759 BCGMEX_1476c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170940.1 1617294 R 717522 CDS YP_005170941.1 378771208 11809760 complement(1618378..1618788) 1 NC_016804.1 hypothetical protein 1618788 11809760 BCGMEX_1477c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170941.1 1618378 R 717522 CDS YP_005170942.1 378771209 11809761 complement(1618805..1619548) 1 NC_016804.1 putative 6-phosphogluconolactonase 1619548 devB 11809761 devB Mycobacterium bovis BCG str. Mexico putative 6-phosphogluconolactonase YP_005170942.1 1618805 R 717522 CDS YP_005170943.1 378771210 11809762 complement(1619545..1620456) 1 NC_016804.1 Differs from Rv1446v by 1aa P192R in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; putative OxpP cycle protein 1620456 opcA 11809762 opcA Mycobacterium bovis BCG str. Mexico putative OxpP cycle protein YP_005170943.1 1619545 R 717522 CDS YP_005170944.1 378771211 11809763 complement(1620509..1622053) 1 NC_016804.1 glucose-6-phosphate 1-dehydrogenase 1622053 zwf2 11809763 zwf2 Mycobacterium bovis BCG str. Mexico glucose-6-phosphate 1-dehydrogenase YP_005170944.1 1620509 R 717522 CDS YP_005170945.1 378771212 11809764 complement(1622050..1623171) 1 NC_016804.1 Differs from Rv1448c by 1aa A244T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Transaldolase 1623171 tal 11809764 tal Mycobacterium bovis BCG str. Mexico Transaldolase YP_005170945.1 1622050 R 717522 CDS YP_005170946.1 378771213 11809765 complement(1623188..1625290) 1 NC_016804.1 Differs from Rv1449c by 1aa D18Y in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; transketolase 1625290 tkt 11809765 tkt Mycobacterium bovis BCG str. Mexico transketolase YP_005170946.1 1623188 R 717522 CDS YP_005170947.1 378771214 11809766 complement(1625729..1629928) 1 NC_016804.1 In Mycobacterium bovis, insertions of 27 bp, 207 bpand 27 bp, substitutions of 60 bp to 63 bp and 11 bp, and a 27 bp deletion, leads to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (1408 aa versus 1329 aa). In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, one 27bp-insertion is missing, leading to a product of 1399 aa; PE-PGRS family protein 1629928 PE_PGRS27 11809766 PE_PGRS27 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170947.1 1625729 R 717522 CDS YP_005170948.1 378771215 11809767 1630330..1631256 1 NC_016804.1 Differs from Rv1451 by 1aa T68A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; protoheme IX farnesyltransferase 1631256 ctaB 11809767 ctaB Mycobacterium bovis BCG str. Mexico protoheme IX farnesyltransferase YP_005170948.1 1630330 D 717522 CDS YP_005170949.1 378771216 11809768 complement(1631305..1633527) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, Tokyo and BCG Mexico, a insertion of 51 bp, several substitutions and a deletion of 207 bp, lead to a smaller product compared to its homolog Mycobacterium bovis (740 aa versus 795 aa). Differs from BCG_1513c by 5aa, G647D, G648I, D649I, G650V, T651A in BCG Tokyo.; PE-PGRS family protein 1633527 PE_PGRS28 11809768 PE_PGRS28 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170949.1 1631305 R 717522 CDS YP_005170950.1 378771217 11809769 1633679..1634944 1 NC_016804.1 Differs from Rv1453 by 1aa Q405P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional activator protein 1634944 11809769 BCGMEX_1486 Mycobacterium bovis BCG str. Mexico putative transcriptional activator protein YP_005170950.1 1633679 D 717522 CDS YP_005170951.1 378771218 11809770 complement(1634972..1635958) 1 NC_016804.1 putative quinone reductase 1635958 qor 11809770 qor Mycobacterium bovis BCG str. Mexico putative quinone reductase YP_005170951.1 1634972 R 717522 CDS YP_005170952.1 378771219 11809771 1635978..1636841 1 NC_016804.1 hypothetical protein 1636841 11809771 BCGMEX_1488 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170952.1 1635978 D 717522 CDS YP_005170953.1 378771220 11809772 complement(1636791..1637723) 1 NC_016804.1 putative unidentified antibiotic-transport integral membrane ABC transporter 1637723 11809772 BCGMEX_1489c Mycobacterium bovis BCG str. Mexico putative unidentified antibiotic-transport integral membrane ABC transporter YP_005170953.1 1636791 R 717522 CDS YP_005170954.1 378771221 11809773 complement(1637835..1638620) 1 NC_016804.1 putative unidentified antibiotic-transport integral membrane ABC transporter 1638620 11809773 BCGMEX_1490c Mycobacterium bovis BCG str. Mexico putative unidentified antibiotic-transport integral membrane ABC transporter YP_005170954.1 1637835 R 717522 CDS YP_005170955.1 378771222 11809774 complement(1638617..1639558) 1 NC_016804.1 putative unidentified antibiotic-transport ATP-binding protein ABC transporter 1639558 11809774 BCGMEX_1491c Mycobacterium bovis BCG str. Mexico putative unidentified antibiotic-transport ATP-binding protein ABC transporter YP_005170955.1 1638617 R 717522 CDS YP_005170956.1 378771223 11809775 complement(1639714..1641489) 1 NC_016804.1 Differs from Rv1459c by 1aa, E113K in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 1641489 11809775 BCGMEX_1492c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005170956.1 1639714 R 717522 CDS YP_005170957.1 378771224 11809776 1641537..1642343 1 NC_016804.1 Differs from Rv1460 by 2aa, F198I, V265 and from Mb1495 by 1aa, F198I in BCG Paasteur, BCG Tokyo and BCG Mexico; transcriptional regulator 1642343 11809776 BCGMEX_1493 Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005170957.1 1641537 D 717522 CDS YP_005170958.1 378771225 11809777 1642340..1644880 1 NC_016804.1 hypothetical protein 1644880 11809777 BCGMEX_1494 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170958.1 1642340 D 717522 CDS YP_005170959.1 378771226 11809778 1644877..1646070 1 NC_016804.1 Differs from Rv1462 by 1aa, D183N in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1646070 11809778 BCGMEX_1495 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170959.1 1644877 D 717522 CDS YP_005170960.1 378771227 11809779 1646067..1646867 1 NC_016804.1 putative ATP-binding protein ABC transporter 1646867 11809779 BCGMEX_1496 Mycobacterium bovis BCG str. Mexico putative ATP-binding protein ABC transporter YP_005170960.1 1646067 D 717522 CDS YP_005170961.1 378771228 11809780 1646869..1648122 1 NC_016804.1 putative cysteine desulfurase 1648122 csd 11809780 csd Mycobacterium bovis BCG str. Mexico putative cysteine desulfurase YP_005170961.1 1646869 D 717522 CDS YP_005170962.1 378771229 11809781 1648119..1648607 1 NC_016804.1 putative nitrogen fixation related protein 1648607 11809781 BCGMEX_1498 Mycobacterium bovis BCG str. Mexico putative nitrogen fixation related protein YP_005170962.1 1648119 D 717522 CDS YP_005170963.1 378771230 11809782 1648582..1648929 1 NC_016804.1 hypothetical protein 1648929 11809782 BCGMEX_1499 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170963.1 1648582 D 717522 CDS YP_005170964.1 378771231 11809783 complement(1649024..1650853) 1 NC_016804.1 putative acyl-CoA dehydrogenase 1650853 fadE15 11809783 fadE15 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005170964.1 1649024 R 717522 CDS YP_005170965.1 378771232 11809784 complement(1650960..1652072) 1 NC_016804.1 PE-PGRS family protein 1652072 PE_PGRS29 11809784 PE_PGRS29 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005170965.1 1650960 R 717522 CDS YP_005170966.1 378771233 11809785 1652314..1654287 1 NC_016804.1 putative cation transporter P-type ATPase D 1654287 ctpD 11809785 ctpD Mycobacterium bovis BCG str. Mexico putative cation transporter P-type ATPase D YP_005170966.1 1652314 D 717522 CDS YP_005170967.1 378771234 11809786 1654331..1654705 1 NC_016804.1 putative thioredoxin 1654705 trxA 11809786 trxA Mycobacterium bovis BCG str. Mexico putative thioredoxin YP_005170967.1 1654331 D 717522 CDS YP_005170968.1 378771235 11809787 1654721..1655092 1 NC_016804.1 putative thioredoxin 1655092 trxB1 11809787 trxB1 Mycobacterium bovis BCG str. Mexico putative thioredoxin YP_005170968.1 1654721 D 717522 CDS YP_005170969.1 378771236 11809788 1655114..1655971 1 NC_016804.1 Differs from Rv1472 by 1aa, S78P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Enoyl-CoA hydratase 1655971 echA12 11809788 echA12 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005170969.1 1655114 D 717522 CDS YP_005170970.1 378771237 11809789 1656007..1657635 1 NC_016804.1 putative macrolide-transport ATP-binding protein ABC transporter 1657635 11809789 BCGMEX_1506 Mycobacterium bovis BCG str. Mexico putative macrolide-transport ATP-binding protein ABC transporter YP_005170970.1 1656007 D 717522 CDS YP_005170971.1 378771238 11809790 1657732..1657923 1 NC_016804.1 Differs from Rv1473A by 1aa, P60S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; transcriptional regulator 1657923 11809790 BCGMEX_1507 Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005170971.1 1657732 D 717522 CDS YP_005170972.1 378771239 11809791 complement(1657992..1658555) 1 NC_016804.1 putative transcriptional regulatory protein 1658555 11809791 BCGMEX_1508c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170972.1 1657992 R 717522 CDS YP_005170973.1 378771240 11809792 complement(1658566..1661397) 1 NC_016804.1 aconitate hydratase 1661397 acn 11809792 acn Mycobacterium bovis BCG str. Mexico aconitate hydratase YP_005170973.1 1658566 R 717522 CDS YP_005170974.1 378771241 11809793 1661555..1662115 1 NC_016804.1 hypothetical protein 1662115 11809793 BCGMEX_1510 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170974.1 1661555 D 717522 CDS YP_005170975.1 378771242 11809794 1662341..1663759 1 NC_016804.1 putative invasion protein 1663759 11809794 BCGMEX_1511 Mycobacterium bovis BCG str. Mexico putative invasion protein YP_005170975.1 1662341 D 717522 CDS YP_005170976.1 378771243 11809795 1663770..1664495 1 NC_016804.1 putative invasion protein 1664495 11809795 BCGMEX_1512 Mycobacterium bovis BCG str. Mexico putative invasion protein YP_005170976.1 1663770 D 717522 CDS YP_005170977.1 378771244 11809796 1664634..1665767 1 NC_016804.1 putative transcriptional regulatory protein 1665767 moxR1 11809796 moxR1 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005170977.1 1664634 D 717522 CDS YP_005170978.1 378771245 11809797 1665764..1666717 1 NC_016804.1 hypothetical protein 1666717 11809797 BCGMEX_1514 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170978.1 1665764 D 717522 CDS YP_005170979.1 378771246 11809798 1666728..1667735 1 NC_016804.1 Differs from Rv1481 and Mb1517 by 1aa, D254N in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1667735 11809798 BCGMEX_1515 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170979.1 1666728 D 717522 CDS YP_005170980.1 378771247 11809799 complement(1667808..1668650) 1 NC_016804.1 hypothetical protein 1668650 11809799 BCGMEX_1516c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170980.1 1667808 R 717522 CDS YP_005170981.1 378771248 11809800 1668791..1669534 1 NC_016804.1 putative 3-oxoacyl-[acyl-carrier protein] reductase 1669534 fabG1 11809800 fabG1 Mycobacterium bovis BCG str. Mexico putative 3-oxoacyl-[acyl-carrier protein] reductase YP_005170981.1 1668791 D 717522 CDS YP_005170982.1 378771249 11809801 1669553..1670362 1 NC_016804.1 Enoyl-[acyl-carrier-protein] reductase 1670362 inhA 11809801 inhA Mycobacterium bovis BCG str. Mexico Enoyl-[acyl-carrier-protein] reductase YP_005170982.1 1669553 D 717522 CDS YP_005170983.1 378771250 11809802 1670368..1671402 1 NC_016804.1 ferrochelatase 1671402 hemZ 11809802 hemZ Mycobacterium bovis BCG str. Mexico ferrochelatase YP_005170983.1 1670368 D 717522 CDS YP_005170984.1 378771251 11809803 complement(1671264..1672235) 1 NC_016804.1 First 270 aa similar to Mb1522c and Rv1486c (but differs by 1aa, N198K), then frameshifts due to extra base. 2GC in BCG Tokyo, 1GC in BCG Pasteur and BCG Mexico; hypothetical protein 1672235 11809803 BCGMEX_1520 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170984.1 1671264 R 717522 CDS YP_005170985.1 378771252 11809804 1672293..1672727 1 NC_016804.1 hypothetical protein 1672727 11809804 BCGMEX_1521 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170985.1 1672293 D 717522 CDS YP_005170986.1 378771253 11809805 1672749..1673894 1 NC_016804.1 hypothetical protein 1673894 11809805 BCGMEX_1522 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170986.1 1672749 D 717522 CDS YP_005170987.1 378771254 11809806 1673904..1674260 1 NC_016804.1 hypothetical protein 1674260 11809806 BCGMEX_1523 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170987.1 1673904 D 717522 CDS YP_005170988.1 378771255 11809807 1674294..1674524 1 NC_016804.1 hypothetical protein 1674524 11809807 BCGMEX_1524 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170988.1 1674294 D 717522 CDS YP_005170989.1 378771256 11809808 1674674..1675981 1 NC_016804.1 hypothetical protein 1675981 11809808 BCGMEX_1525 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170989.1 1674674 D 717522 CDS YP_005170990.1 378771257 11809809 complement(1676560..1677318) 1 NC_016804.1 hypothetical protein 1677318 11809809 BCGMEX_1526c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170990.1 1676560 R 717522 CDS YP_005170991.1 378771258 11809810 1677509..1679356 1 NC_016804.1 putative methylmalonyl-CoA mutase small subunit 1679356 mutA 11809810 mutA Mycobacterium bovis BCG str. Mexico putative methylmalonyl-CoA mutase small subunit YP_005170991.1 1677509 D 717522 CDS YP_005170992.1 378771259 11809811 1679357..1681609 1 NC_016804.1 methylmalonyl-CoA mutase 1681609 mutB 11809811 mutB Mycobacterium bovis BCG str. Mexico methylmalonyl-CoA mutase YP_005170992.1 1679357 D 717522 CDS YP_005170993.1 378771260 11809812 1681623..1681925 1 NC_016804.1 hypothetical protein 1681925 11809812 BCGMEX_1529 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170993.1 1681623 D 717522 CDS YP_005170994.1 378771261 11809813 1681922..1682239 1 NC_016804.1 hypothetical protein 1682239 11809813 BCGMEX_1530 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170994.1 1681922 D 717522 CDS YP_005170995.1 378771262 11809814 1682236..1683240 1 NC_016804.1 arginine/ornithine transport system ATPase 1683240 11809814 BCGMEX_1531 Mycobacterium bovis BCG str. Mexico arginine/ornithine transport system ATPase YP_005170995.1 1682236 D 717522 CDS YP_005170996.1 378771263 11809815 1683293..1684582 1 NC_016804.1 putative esterase 1684582 lipL 11809815 lipL Mycobacterium bovis BCG str. Mexico putative esterase YP_005170996.1 1683293 D 717522 CDS YP_005170997.1 378771264 11809816 complement(1684655..1685272) 1 NC_016804.1 Differs from Rv1498c by 1aa, H191R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative methyltransferase 1685272 11809816 BCGMEX_1533c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005170997.1 1684655 R 717522 CDS YP_005170998.1 378771265 11809817 complement(1685486..1685677) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transition at the 5' start leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (63 aa versus 70 aa); hypothetical protein 1685677 11809817 BCGMEX_1534c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170998.1 1685486 R 717522 CDS YP_005170999.1 378771266 11809818 1685759..1686157 1 NC_016804.1 hypothetical protein 1686157 11809818 BCGMEX_1535 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005170999.1 1685759 D 717522 CDS YP_005171000.1 378771267 11809819 1686202..1687230 1 NC_016804.1 Differs from Rv1500 and Mb1538 by 1aa, E45D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative glycosyl transferase 1687230 11809819 BCGMEX_1536 Mycobacterium bovis BCG str. Mexico putative glycosyl transferase YP_005171000.1 1686202 D 717522 CDS YP_005171001.1 378771268 11809820 1687242..1688063 1 NC_016804.1 hypothetical protein 1688063 11809820 BCGMEX_1537 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171001.1 1687242 D 717522 CDS YP_005171002.1 378771269 11809821 1688276..1689175 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium tuberculosis strain H37Rv, Rv1502 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base deletion, splits Rv1502 into 2 parts, Mb1540 and Mb1541. Differs from Rv1502 by 1aa, C213Y in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1689175 11809821 BCGMEX_1538 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171002.1 1688276 D 717522 CDS YP_005171003.1 378771270 11809822 complement(1689348..1690496) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1503c and Rv1504c exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo,BCG Mexico, and Mycobacterium bovis, a single base transversion leads to a single product. Differs from Rv1503c by 1aa, K316E in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; TDP-4-oxo-6-deoxy-D-glucose transaminase 1690496 11809822 BCGMEX_1539c Mycobacterium bovis BCG str. Mexico TDP-4-oxo-6-deoxy-D-glucose transaminase YP_005171003.1 1689348 R 717522 CDS YP_005171004.1 378771271 11809823 complement(1690633..1691298) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1503c and Rv1504c exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a single base transversion leads to a single product. Differs from Rv1503c by 1aa, K316E in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1691298 11809823 BCGMEX_1540c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171004.1 1690633 R 717522 CDS YP_005171005.1 378771272 11809824 1691491..1692255 1 NC_016804.1 Differs from Rv1517 by 1aa, F188L in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1692255 11809824 BCGMEX_1541 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171005.1 1691491 D 717522 CDS YP_005171006.1 378771273 11809825 1692264..1693223 1 NC_016804.1 Differs from Rv1518 by 2aa, R266S, L317M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1693223 11809825 BCGMEX_1542 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171006.1 1692264 D 717522 CDS YP_005171007.1 378771274 11809826 1693353..1693622 1 NC_016804.1 hypothetical protein 1693622 11809826 BCGMEX_1543 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171007.1 1693353 D 717522 CDS YP_005171008.1 378771275 11809827 1693648..1694688 1 NC_016804.1 putative sugar transferase 1694688 11809827 BCGMEX_1544 Mycobacterium bovis BCG str. Mexico putative sugar transferase YP_005171008.1 1693648 D 717522 CDS YP_005171009.1 378771276 11809828 1694922..1696673 1 NC_016804.1 Differs from Rv1521 by 1aa, I74S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA synthetase 1696673 fadD25 11809828 fadD25 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005171009.1 1694922 D 717522 CDS YP_005171010.1 378771277 11809829 complement(1696909..1700232) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a single base transversion creating a stop codon, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (1107 aa versus 1146 aa). Differs from Rv1522c (1146 aa) by 1aa, P381S, and from Mb1549c, (1107 aa) by 2aa, T204A, S947N in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane transport protein 1700232 mmpL12 11809829 mmpL12 Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005171010.1 1696909 R 717522 CDS YP_005171011.1 378771278 11809830 1700273..1701316 1 NC_016804.1 putative methyltransferase 1701316 11809830 BCGMEX_1547 Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005171011.1 1700273 D 717522 CDS YP_005171012.1 378771279 11809831 1701346..1702590 1 NC_016804.1 glycosyltransferase 1702590 11809831 BCGMEX_1548 Mycobacterium bovis BCG str. Mexico glycosyltransferase YP_005171012.1 1701346 D 717522 CDS YP_005171013.1 378771280 11809832 1702637..1703422 1 NC_016804.1 putative rhamnosyl transferase 1703422 wbbL2 11809832 wbbL2 Mycobacterium bovis BCG str. Mexico putative rhamnosyl transferase YP_005171013.1 1702637 D 717522 CDS YP_005171014.1 378771281 11809833 complement(1703400..1704680) 1 NC_016804.1 glycosyltransferase 1704680 11809833 BCGMEX_1550c Mycobacterium bovis BCG str. Mexico glycosyltransferase YP_005171014.1 1703400 R 717522 CDS YP_005171015.1 378771282 11809834 complement(1704703..1711029) 1 NC_016804.1 Differs from Rv1527c by 2aa, T532P, L1439F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyketide synthase 1711029 pks5 11809834 pks5 Mycobacterium bovis BCG str. Mexico putative polyketide synthase YP_005171015.1 1704703 R 717522 CDS YP_005171016.1 378771283 11809835 complement(1711573..1712070) 1 NC_016804.1 putative polyketide synthase associated protein 1712070 papA4 11809835 papA4 Mycobacterium bovis BCG str. Mexico putative polyketide synthase associated protein YP_005171016.1 1711573 R 717522 CDS YP_005171017.1 378771284 11809836 1712122..1713876 1 NC_016804.1 Differs from Rv1529 and Mb1556 by 1aa, G289D in BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA synthetase 1713876 fadD24 11809836 fadD24 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005171017.1 1712122 D 717522 CDS YP_005171018.1 378771285 11809837 1713993..1715096 1 NC_016804.1 Differs from Rv1530 and Mb1557 by 1aa, L330P in BCG Pasteur, BCG Tokyo and BCG Mexico; putative alcohol dehydrogenase 1715096 adh 11809837 adh Mycobacterium bovis BCG str. Mexico putative alcohol dehydrogenase YP_005171018.1 1713993 D 717522 CDS YP_005171019.1 378771286 11809838 1715093..1715659 1 NC_016804.1 hypothetical protein 1715659 11809838 BCGMEX_1555 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171019.1 1715093 D 717522 CDS YP_005171020.1 378771287 11809839 complement(1715736..1716170) 1 NC_016804.1 hypothetical protein 1716170 11809839 BCGMEX_1556c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171020.1 1715736 R 717522 CDS YP_005171021.1 378771288 11809840 1716230..1717357 1 NC_016804.1 hypothetical protein 1717357 11809840 BCGMEX_1557 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171021.1 1716230 D 717522 CDS YP_005171022.1 378771289 11809841 1717354..1718031 1 NC_016804.1 putative transcriptional regulator 1718031 11809841 BCGMEX_1558 Mycobacterium bovis BCG str. Mexico putative transcriptional regulator YP_005171022.1 1717354 D 717522 CDS YP_005171023.1 378771290 11809842 1718596..1718832 1 NC_016804.1 hypothetical protein 1718832 11809842 BCGMEX_1559 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171023.1 1718596 D 717522 CDS YP_005171024.1 378771291 11809843 1719139..1722264 1 NC_016804.1 Differs from Rv1536 by 1aa, A926P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; isoleucyl-tRNA synthetase 1722264 ileS 11809843 ileS Mycobacterium bovis BCG str. Mexico isoleucyl-tRNA synthetase YP_005171024.1 1719139 D 717522 CDS YP_005171025.1 378771292 11809844 1722476..1723867 1 NC_016804.1 DNA polymerase IV 1723867 dinX 11809844 dinX Mycobacterium bovis BCG str. Mexico DNA polymerase IV YP_005171025.1 1722476 D 717522 CDS YP_005171026.1 378771293 11809845 complement(1723832..1724812) 1 NC_016804.1 L-asparaginase 1724812 ansA 11809845 ansA Mycobacterium bovis BCG str. Mexico L-asparaginase YP_005171026.1 1723832 R 717522 CDS YP_005171027.1 378771294 11809846 1724864..1725472 1 NC_016804.1 lipoprotein signal peptidase 1725472 lspA 11809846 lspA Mycobacterium bovis BCG str. Mexico lipoprotein signal peptidase YP_005171027.1 1724864 D 717522 CDS YP_005171028.1 378771295 11809847 1725465..1726391 1 NC_016804.1 hypothetical protein 1726391 11809847 BCGMEX_1564 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171028.1 1725465 D 717522 CDS YP_005171029.1 378771296 11809848 complement(1726398..1726991) 1 NC_016804.1 putative lipoprotein 1726991 lprI 11809848 lprI Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171029.1 1726398 R 717522 CDS YP_005171030.1 378771297 11809849 complement(1727046..1727456) 1 NC_016804.1 putative hemoglobin 1727456 glbN 11809849 glbN Mycobacterium bovis BCG str. Mexico putative hemoglobin YP_005171030.1 1727046 R 717522 CDS YP_005171031.1 378771298 11809850 1727684..1728709 1 NC_016804.1 putative fatty acyl-CoA reductase 1728709 11809850 BCGMEX_1567 Mycobacterium bovis BCG str. Mexico putative fatty acyl-CoA reductase YP_005171031.1 1727684 D 717522 CDS YP_005171032.1 378771299 11809851 1728714..1728812 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, and Mycobacterium bovis, Rv1544 and Mb1571 exist as a single gene. In Mycobacterium bovis BCG Pasteur and BCG Mexico, two genes exist as a result of a 10 bp deletion that has occurred. In BCG Tokyo exists same as Rv1544 and Mb157; hypothetical protein 1728812 11809851 BCGMEX_1568 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171032.1 1728714 D 717522 CDS YP_005171033.1 378771300 11809852 1728812..1729507 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, and Mycobacterium bovis, Rv1544 and Mb1571 exist as a single gene. In Mycobacterium bovis BCG Pasteur and BCG Mexico, two genes exist as a result of a 10 bp deletion that has occurred. In BCG Tokyo exists same as Rv1544 and Mb1571.; putative ketoacyl reductase 1729507 11809852 BCGMEX_1569 Mycobacterium bovis BCG str. Mexico putative ketoacyl reductase YP_005171033.1 1728812 D 717522 CDS YP_005171034.1 378771301 11809853 1729529..1729756 1 NC_016804.1 hypothetical protein 1729756 11809853 BCGMEX_1570 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171034.1 1729529 D 717522 CDS YP_005171035.1 378771302 11809854 1729805..1730236 1 NC_016804.1 hypothetical protein 1730236 11809854 BCGMEX_1571 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171035.1 1729805 D 717522 CDS YP_005171036.1 378771303 11809855 1730304..1733858 1 NC_016804.1 DNA polymerase III subunit alpha 1733858 dnaE 11809855 dnaE Mycobacterium bovis BCG str. Mexico DNA polymerase III subunit alpha YP_005171036.1 1730304 D 717522 CDS YP_005171037.1 378771304 11809856 complement(1733907..1735943) 1 NC_016804.1 Differs from Rv1548c by 1aa, G258D, and from Mb1575c by 1aa, V68A in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 1735943 PPE21 11809856 PPE21 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171037.1 1733907 R 717522 CDS YP_005171038.1 378771305 11809857 1736100..1738043 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1549 and Rv1550 exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, two single base insertions lead to a single product. Differs from Rv1550 by 1aa, S362L in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative fatty acid CoA ligase 1738043 fadD11 11809857 fadD11 Mycobacterium bovis BCG str. Mexico putative fatty acid CoA ligase YP_005171038.1 1736100 D 717522 CDS YP_005171039.1 378771306 11809858 1738057..1739922 1 NC_016804.1 glycerol-3-phosphate acyltransferase 1739922 plsB1 11809858 plsB1 Mycobacterium bovis BCG str. Mexico glycerol-3-phosphate acyltransferase YP_005171039.1 1738057 D 717522 CDS YP_005171040.1 378771307 11809859 1740292..1742043 1 NC_016804.1 Fumarate reductase flavoprotein subunit 1742043 frdA 11809859 frdA Mycobacterium bovis BCG str. Mexico Fumarate reductase flavoprotein subunit YP_005171040.1 1740292 D 717522 CDS YP_005171041.1 378771308 11809860 1742046..1743176 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1553 and Rv1554 exist as 2 genes. In Mycobacterium bovis (Mb1579), a 4bp insertion leads to a single product and in Mycobacterium bovis BCG Pasteur and BCG Mexicoa 10 bp insertion leads to insertion of two additional Gly codons. In Mycobacterium bovis BCG Tokyo, a 9 bp insertion leads to insertion of three additional Gly codons. 16Gs in BCG Tokyo, 17Gs in BCG Pasteur and BCG Mexico.; putative fumarate reductase (iron-sulfur subunit) frdB and (membrane anchor subunit) frdC 1743176 frdBC 11809860 frdBC Mycobacterium bovis BCG str. Mexico putative fumarate reductase (iron-sulfur subunit) frdB and (membrane anchor subunit) frdC YP_005171041.1 1742046 D 717522 CDS YP_005171042.1 378771309 11809861 1743173..1743550 1 NC_016804.1 Fumarate reductase subunit D 1743550 frdD 11809861 frdD Mycobacterium bovis BCG str. Mexico Fumarate reductase subunit D YP_005171042.1 1743173 D 717522 CDS YP_005171043.1 378771310 11809862 1743618..1744226 1 NC_016804.1 putative regulatory protein 1744226 11809862 BCGMEX_1579 Mycobacterium bovis BCG str. Mexico putative regulatory protein YP_005171043.1 1743618 D 717522 CDS YP_005171044.1 378771311 11809863 1744365..1744811 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a 2153 bp insertion leads to a new protein with no Equivalent in Mycobacterium tuberculosis strain H37Rv. Belongs to the TbD1 region; hypothetical protein 1744811 mmpS6 11809863 mmpS6 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171044.1 1744365 D 717522 CDS YP_005171045.1 378771312 11809864 1744808..1747711 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a 2153 bp insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Belongs to the TbD1 region; putative transmembrane transport protein 1747711 mmpL6 11809864 mmpL6 Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005171045.1 1744808 D 717522 CDS YP_005171046.1 378771313 11809865 1747721..1748167 1 NC_016804.1 hypothetical protein 1748167 11809865 BCGMEX_1582 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171046.1 1747721 D 717522 CDS YP_005171047.1 378771314 11809866 1748202..1749491 1 NC_016804.1 Threonine dehydratase 1749491 ilvA 11809866 ilvA Mycobacterium bovis BCG str. Mexico Threonine dehydratase YP_005171047.1 1748202 D 717522 CDS YP_005171048.1 378771315 11809867 1749529..1749747 1 NC_016804.1 hypothetical protein 1749747 11809867 BCGMEX_1584 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171048.1 1749529 D 717522 CDS YP_005171049.1 378771316 11809868 1749753..1750157 1 NC_016804.1 hypothetical protein 1750157 11809868 BCGMEX_1585 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171049.1 1749753 D 717522 CDS YP_005171050.1 378771317 11809869 complement(1750174..1750734) 1 NC_016804.1 Malto-oligosyltrehalose trehalohydrolase 1750734 treZb 11809869 treZb Mycobacterium bovis BCG str. Mexico Malto-oligosyltrehalose trehalohydrolase YP_005171050.1 1750174 R 717522 CDS YP_005171051.1 378771318 11809870 complement(1750731..1751915) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, and Mycobacterium bovis, treZa and treZb exist as a single gene, treZ. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, a single base deletion leads to frameshift and two genes, treZa and treZb; Malto-oligosyltrehalose trehalohydrolase 1751915 treZa 11809870 treZa Mycobacterium bovis BCG str. Mexico Malto-oligosyltrehalose trehalohydrolase YP_005171051.1 1750731 R 717522 CDS YP_005171052.1 378771319 11809871 complement(1751908..1754205) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and in Mycobacterium tuberculosis strain H37Rv, treY exists as a single gene. In Mycobacterium bovis, a large deletion of 806 bp, RD17, splits Rv1563c into two parts, treYa and treYb; Malto-oligosyltrehalose synthase 1754205 treY 11809871 treY Mycobacterium bovis BCG str. Mexico Malto-oligosyltrehalose synthase YP_005171052.1 1751908 R 717522 CDS YP_005171053.1 378771320 11809872 complement(1754209..1756374) 1 NC_016804.1 Maltooligosyltrehalose synthase 1756374 treX 11809872 treX Mycobacterium bovis BCG str. Mexico Maltooligosyltrehalose synthase YP_005171053.1 1754209 R 717522 CDS YP_005171054.1 378771321 11809873 complement(1756413..1758602) 1 NC_016804.1 hypothetical protein 1758602 11809873 BCGMEX_1590c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171054.1 1756413 R 717522 CDS YP_005171055.1 378771322 11809874 complement(1758701..1759393) 1 NC_016804.1 putative inv protein 1759393 11809874 BCGMEX_1591c Mycobacterium bovis BCG str. Mexico putative inv protein YP_005171055.1 1758701 R 717522 CDS YP_005171056.1 378771323 11809875 complement(1759633..1759917) 1 NC_016804.1 hypothetical protein 1759917 11809875 BCGMEX_1592c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171056.1 1759633 R 717522 CDS YP_005171057.1 378771324 11809876 1760165..1761478 1 NC_016804.1 Adenosylmethionine-8-amino-7-oxononanoate transaminase 1761478 bioA 11809876 bioA Mycobacterium bovis BCG str. Mexico Adenosylmethionine-8-amino-7-oxononanoate transaminase YP_005171057.1 1760165 D 717522 CDS YP_005171058.1 378771325 11809877 1761475..1762635 1 NC_016804.1 8-amino-7-oxononanoate synthase 1762635 bioF1 11809877 bioF1 Mycobacterium bovis BCG str. Mexico 8-amino-7-oxononanoate synthase YP_005171058.1 1761475 D 717522 CDS YP_005171059.1 378771326 11809878 1762632..1763312 1 NC_016804.1 Differs from Rv1570 by 2aa, V134A, T191M, and from Mb1597 by 1aa, V134A in BCG Pasteur, BCG Tokyo and BCG Mexico; dethiobiotin synthetase 1763312 bioD 11809878 bioD Mycobacterium bovis BCG str. Mexico dethiobiotin synthetase YP_005171059.1 1762632 D 717522 CDS YP_005171060.1 378771327 11809879 1763312..1763821 1 NC_016804.1 hypothetical protein 1763821 11809879 BCGMEX_1596 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171060.1 1763312 D 717522 CDS YP_005171061.1 378771328 11809880 complement(1763967..1764923) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv and Mycobacterium bovis, Rv1587c possibly exists as a pseudogene that has been disrupted when the phage entered. In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, the prophage is absent and the C-terminal part of protein differs accordingly; REP13E12 repeat protein 1764923 11809880 BCGMEX_1597c Mycobacterium bovis BCG str. Mexico REP13E12 repeat protein YP_005171061.1 1763967 R 717522 CDS YP_005171062.1 378771329 11809881 complement(1764694..1765362) 1 NC_016804.1 REP13E12 repeat protein 1765362 11809881 BCGMEX_1598c Mycobacterium bovis BCG str. Mexico REP13E12 repeat protein YP_005171062.1 1764694 R 717522 CDS YP_005171063.1 378771330 11809882 1765810..1766859 1 NC_016804.1 biotin synthase 1766859 bioB 11809882 bioB Mycobacterium bovis BCG str. Mexico biotin synthase YP_005171063.1 1765810 D 717522 CDS YP_005171064.1 378771331 11809883 1766860..1767099 1 NC_016804.1 hypothetical protein 1767099 11809883 BCGMEX_1600 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171064.1 1766860 D 717522 CDS YP_005171065.1 378771332 11809884 1767096..1767761 1 NC_016804.1 putative transmembrane protein 1767761 11809884 BCGMEX_1601 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171065.1 1767096 D 717522 CDS YP_005171066.1 378771333 11809885 complement(1767926..1769266) 1 NC_016804.1 Differs from Rv1592c by 1aa, V322I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1769266 11809885 BCGMEX_1602c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171066.1 1767926 R 717522 CDS YP_005171067.1 378771334 11809886 complement(1769523..1770233) 1 NC_016804.1 hypothetical protein 1770233 11809886 BCGMEX_1603c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171067.1 1769523 R 717522 CDS YP_005171068.1 378771335 11809887 1770282..1771331 1 NC_016804.1 quinolinate synthetase 1771331 nadA 11809887 nadA Mycobacterium bovis BCG str. Mexico quinolinate synthetase YP_005171068.1 1770282 D 717522 CDS YP_005171069.1 378771336 11809888 1771331..1772914 1 NC_016804.1 L-aspartate oxidase 1772914 nadB 11809888 nadB Mycobacterium bovis BCG str. Mexico L-aspartate oxidase YP_005171069.1 1771331 D 717522 CDS YP_005171070.1 378771337 11809889 1772914..1773771 1 NC_016804.1 Differs from Rv1596 by 1aa, D64N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; nicotinate-nucleotide pyrophosphatase 1773771 nadC 11809889 nadC Mycobacterium bovis BCG str. Mexico nicotinate-nucleotide pyrophosphatase YP_005171070.1 1772914 D 717522 CDS YP_005171071.1 378771338 11809890 1773820..1774578 1 NC_016804.1 Differs from Rv1597 by 2aa, D21G, M93L, and from Mb1623 by 1aa, M93L in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1774578 11809890 BCGMEX_1607 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171071.1 1773820 D 717522 CDS YP_005171072.1 378771339 11809891 complement(1774599..1775009) 1 NC_016804.1 hypothetical protein 1775009 11809891 BCGMEX_1608c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171072.1 1774599 R 717522 CDS YP_005171073.1 378771340 11809892 1775109..1776425 1 NC_016804.1 histidinol dehydrogenase 1776425 hisD 11809892 hisD Mycobacterium bovis BCG str. Mexico histidinol dehydrogenase YP_005171073.1 1775109 D 717522 CDS YP_005171074.1 378771341 11809893 1776422..1777564 1 NC_016804.1 histidinol-phosphate aminotransferase 1777564 hisC1 11809893 hisC1 Mycobacterium bovis BCG str. Mexico histidinol-phosphate aminotransferase YP_005171074.1 1776422 D 717522 CDS YP_005171075.1 378771342 11809894 1777561..1778193 1 NC_016804.1 imidazoleglycerol-phosphate dehydratase 1778193 hisB 11809894 hisB Mycobacterium bovis BCG str. Mexico imidazoleglycerol-phosphate dehydratase YP_005171075.1 1777561 D 717522 CDS YP_005171076.1 378771343 11809895 1778190..1778810 1 NC_016804.1 Differs from Rv1602 by 1aa, N201S in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; imidazole glycerol phosphate synthase 1778810 hisH 11809895 hisH Mycobacterium bovis BCG str. Mexico imidazole glycerol phosphate synthase YP_005171076.1 1778190 D 717522 CDS YP_005171077.1 378771344 11809896 1778820..1779557 1 NC_016804.1 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1779557 hisA 11809896 hisA Mycobacterium bovis BCG str. Mexico 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_005171077.1 1778820 D 717522 CDS YP_005171078.1 378771345 11809897 1779565..1780377 1 NC_016804.1 Differs from Rv1604 by 3aa, H93Y, Q124P, L251P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative inositol-monophosphatase 1780377 impA 11809897 impA Mycobacterium bovis BCG str. Mexico putative inositol-monophosphatase YP_005171078.1 1779565 D 717522 CDS YP_005171079.1 378771346 11809898 1780379..1781182 1 NC_016804.1 Differs from Rv1605 by 1aa, L121P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; imidazole glycerol phosphate synthase 1781182 hisF 11809898 hisF Mycobacterium bovis BCG str. Mexico imidazole glycerol phosphate synthase YP_005171079.1 1780379 D 717522 CDS YP_005171080.1 378771347 11809899 1781179..1781526 1 NC_016804.1 phosphoribosyl-AMP cyclohydrolase 1781526 hisI 11809899 hisI Mycobacterium bovis BCG str. Mexico phosphoribosyl-AMP cyclohydrolase YP_005171080.1 1781179 D 717522 CDS YP_005171081.1 378771348 11809900 1781707..1782789 1 NC_016804.1 putative ionic transporter integral membrane protein 1782789 chaA 11809900 chaA Mycobacterium bovis BCG str. Mexico putative ionic transporter integral membrane protein YP_005171081.1 1781707 D 717522 CDS YP_005171082.1 378771349 11809901 complement(1782824..1783288) 1 NC_016804.1 putative peroxidoxin 1783288 bcpB 11809901 bcpB Mycobacterium bovis BCG str. Mexico putative peroxidoxin YP_005171082.1 1782824 R 717522 CDS YP_005171083.1 378771350 11809902 1783429..1784979 1 NC_016804.1 anthranilate synthase 1784979 trpE 11809902 trpE Mycobacterium bovis BCG str. Mexico anthranilate synthase YP_005171083.1 1783429 D 717522 CDS YP_005171084.1 378771351 11809903 1785017..1785676 1 NC_016804.1 hypothetical protein 1785676 11809903 BCGMEX_1620 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171084.1 1785017 D 717522 CDS YP_005171085.1 378771352 11809904 1785766..1786584 1 NC_016804.1 indole-3-glycerol phosphate synthase 1786584 trpC 11809904 trpC Mycobacterium bovis BCG str. Mexico indole-3-glycerol phosphate synthase YP_005171085.1 1785766 D 717522 CDS YP_005171086.1 378771353 11809905 1786653..1787885 1 NC_016804.1 tryptophan synthase subunit beta 1787885 trpB 11809905 trpB Mycobacterium bovis BCG str. Mexico tryptophan synthase subunit beta YP_005171086.1 1786653 D 717522 CDS YP_005171087.1 378771354 11809906 1787885..1788697 1 NC_016804.1 tryptophan synthase subunit alpha 1788697 trpA 11809906 trpA Mycobacterium bovis BCG str. Mexico tryptophan synthase subunit alpha YP_005171087.1 1787885 D 717522 CDS YP_005171088.1 378771355 11809907 1788697..1790103 1 NC_016804.1 prolipoprotein diacylglyceryl transferase 1790103 lgt 11809907 lgt Mycobacterium bovis BCG str. Mexico prolipoprotein diacylglyceryl transferase YP_005171088.1 1788697 D 717522 CDS YP_005171089.1 378771356 11809908 1790779..1791219 1 NC_016804.1 hypothetical protein 1791219 11809908 BCGMEX_1625 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171089.1 1790779 D 717522 CDS YP_005171090.1 378771357 11809909 1791209..1791607 1 NC_016804.1 hypothetical protein 1791607 11809909 BCGMEX_1626 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171090.1 1791209 D 717522 CDS YP_005171091.1 378771358 11809910 1791715..1793133 1 NC_016804.1 Differs from Mb1643 by 1aa, E220D in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Pyruvate kinase 1793133 pykA 11809910 pykA Mycobacterium bovis BCG str. Mexico Pyruvate kinase YP_005171091.1 1791715 D 717522 CDS YP_005171092.1 378771359 11809911 1793141..1794043 1 NC_016804.1 Differs from Rv1618 by 1aa, L121H in Mycobacterium tuberculosis CDC1331, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA thioesterase II 1794043 tesB1 11809911 tesB1 Mycobacterium bovis BCG str. Mexico acyl-CoA thioesterase II YP_005171092.1 1793141 D 717522 CDS YP_005171093.1 378771360 11809912 1794101..1795555 1 NC_016804.1 hypothetical protein 1795555 11809912 BCGMEX_1629 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171093.1 1794101 D 717522 CDS YP_005171094.1 378771361 11809913 complement(1795489..1797219) 1 NC_016804.1 Component linked with the assembly of cytochrome' transport transmembrane ATP-binding protein; putative ABC transporter 1797219 cydC 11809913 cydC Mycobacterium bovis BCG str. Mexico putative ABC transporter YP_005171094.1 1795489 R 717522 CDS YP_005171095.1 378771362 11809914 complement(1797216..1798799) 1 NC_016804.1 Component linked with the assembly of cytochrome' transport transmembrane ATP-binding protein; putative ABC transporter 1798799 cydD 11809914 cydD Mycobacterium bovis BCG str. Mexico putative ABC transporter YP_005171095.1 1797216 R 717522 CDS YP_005171096.1 378771363 11809915 complement(1798886..1799926) 1 NC_016804.1 putative integral membrane cytochrome d ubiquinol oxidase subunit II 1799926 cydB 11809915 cydB Mycobacterium bovis BCG str. Mexico putative integral membrane cytochrome d ubiquinol oxidase subunit II YP_005171096.1 1798886 R 717522 CDS YP_005171097.1 378771364 11809916 complement(1799956..1801413) 1 NC_016804.1 putative integral membrane cytochrome d ubiquinol oxidase subunit I 1801413 cydA 11809916 cydA Mycobacterium bovis BCG str. Mexico putative integral membrane cytochrome d ubiquinol oxidase subunit I YP_005171097.1 1799956 R 717522 CDS YP_005171098.1 378771365 11809917 complement(1801524..1802111) 1 NC_016804.1 Differs from Rv1624c by 1aa, A178T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1802111 11809917 BCGMEX_1634c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171098.1 1801524 R 717522 CDS YP_005171099.1 378771366 11809918 complement(1802140..1803396) 1 NC_016804.1 membrane-anchored Adenylyl cyclase 1803396 cya 11809918 cya Mycobacterium bovis BCG str. Mexico membrane-anchored Adenylyl cyclase YP_005171099.1 1802140 R 717522 CDS YP_005171100.1 378771367 11809920 1803706..1804323 1 NC_016804.1 putative two-component system transcriptional regulator 1804323 11809920 BCGMEX_1636 Mycobacterium bovis BCG str. Mexico putative two-component system transcriptional regulator YP_005171100.1 1803706 D 717522 CDS YP_005171101.1 378771368 11809921 complement(1804391..1805599) 1 NC_016804.1 Lipid-transfer protein 1805599 11809921 BCGMEX_1637c Mycobacterium bovis BCG str. Mexico Lipid-transfer protein YP_005171101.1 1804391 R 717522 CDS YP_005171102.1 378771369 11809922 complement(1805596..1806087) 1 NC_016804.1 Differs from Rv1628c and Mb1654c by 1aa, V93A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1806087 11809922 BCGMEX_1638c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171102.1 1805596 R 717522 CDS YP_005171103.1 378771370 11809923 1806191..1808905 1 NC_016804.1 DNA polymerase I 1808905 polA 11809923 polA Mycobacterium bovis BCG str. Mexico DNA polymerase I YP_005171103.1 1806191 D 717522 CDS YP_005171104.1 378771371 11809924 1809068..1810513 1 NC_016804.1 Differs from Rv1630 by 1aa, T440A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 30S ribosomal protein S1 1810513 rpsA 11809924 rpsA Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S1 YP_005171104.1 1809068 D 717522 CDS YP_005171105.1 378771372 11809925 1810539..1811762 1 NC_016804.1 dephospho-CoA kinase 1811762 coaE 11809925 coaE Mycobacterium bovis BCG str. Mexico dephospho-CoA kinase YP_005171105.1 1810539 D 717522 CDS YP_005171106.1 378771373 11809926 complement(1811913..1812356) 1 NC_016804.1 hypothetical protein 1812356 11809926 BCGMEX_1642c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171106.1 1811913 R 717522 CDS YP_005171107.1 378771374 11809927 1812601..1814697 1 NC_016804.1 Differs from Rv1633 and Mb1659 by 1aa, S405T in BCG Pasteur, BCG Tokyo and BCG Mexico; excinuclease ABC subunit B 1814697 uvrB 11809927 uvrB Mycobacterium bovis BCG str. Mexico excinuclease ABC subunit B YP_005171107.1 1812601 D 717522 CDS YP_005171108.1 378771375 11809928 1814694..1816109 1 NC_016804.1 Differs from Rv1634 by 2aa, Q13E, R198G, and from Mb1660 by 1aa, Q13E in BCG Pasteur, BCG Tokyo and BCG Mexico; putative drug efflux membrane protein 1816109 11809928 BCGMEX_1644 Mycobacterium bovis BCG str. Mexico putative drug efflux membrane protein YP_005171108.1 1814694 D 717522 CDS YP_005171109.1 378771376 11809929 complement(1816098..1817768) 1 NC_016804.1 hypothetical protein 1817768 11809929 BCGMEX_1645c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171109.1 1816098 R 717522 CDS YP_005171110.1 378771377 11809930 1817977..1818417 1 NC_016804.1 hypothetical protein 1818417 11809930 BCGMEX_1646 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171110.1 1817977 D 717522 CDS YP_005171111.1 378771378 11809931 complement(1818424..1819218) 1 NC_016804.1 hypothetical protein 1819218 11809931 BCGMEX_1647c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171111.1 1818424 R 717522 CDS YP_005171112.1 378771379 11809932 1819267..1822185 1 NC_016804.1 excinuclease ABC subunit A 1822185 uvrA 11809932 uvrA Mycobacterium bovis BCG str. Mexico excinuclease ABC subunit A YP_005171112.1 1819267 D 717522 CDS YP_005171113.1 378771380 11809933 complement(1822242..1822499) 1 NC_016804.1 hypothetical protein 1822499 11809933 BCGMEX_1649c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171113.1 1822242 R 717522 CDS YP_005171114.1 378771381 11809934 complement(1822515..1823984) 1 NC_016804.1 hypothetical protein 1823984 11809934 BCGMEX_1650c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171114.1 1822515 R 717522 CDS YP_005171115.1 378771382 11809935 complement(1824043..1827561) 1 NC_016804.1 Differs from Rv1640c by 2aa, E769D, G944D, and from Mb1667c by 1aa, E769D in BCG Pasteur, BCG Tokyo and BCG Mexico; lysyl-tRNA synthetase 1827561 lysS 11809935 lysS Mycobacterium bovis BCG str. Mexico lysyl-tRNA synthetase YP_005171115.1 1824043 R 717522 CDS YP_005171116.1 378771383 11809936 1827798..1828403 1 NC_016804.1 Differs from Rv1641 and Mb1668 by 1aa, S34A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative initiation factor IF-3 1828403 infC 11809936 infC Mycobacterium bovis BCG str. Mexico putative initiation factor IF-3 YP_005171116.1 1827798 D 717522 CDS YP_005171117.1 378771384 11809937 1828453..1828647 1 NC_016804.1 50S ribosomal protein L35 1828647 rpmI 11809937 rpmI Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L35 YP_005171117.1 1828453 D 717522 CDS YP_005171118.1 378771385 11809938 1828709..1829098 1 NC_016804.1 50S ribosomal protein L20 1829098 rplT 11809938 rplT Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L20 YP_005171118.1 1828709 D 717522 CDS YP_005171119.1 378771386 11809939 1829131..1829913 1 NC_016804.1 Differs from Rv1644 by 1aa, P232L in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative 23S rRNA methyltransferase 1829913 tsnR 11809939 tsnR Mycobacterium bovis BCG str. Mexico putative 23S rRNA methyltransferase YP_005171119.1 1829131 D 717522 CDS YP_005171120.1 378771387 11809940 complement(1829924..1830979) 1 NC_016804.1 hypothetical protein 1830979 11809940 BCGMEX_1656c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171120.1 1829924 R 717522 CDS YP_005171121.1 378771388 11809941 1831289..1832221 1 NC_016804.1 PE family protein 1832221 PE17 11809941 PE17 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171121.1 1831289 D 717522 CDS YP_005171122.1 378771389 11809942 1832299..1833249 1 NC_016804.1 Differs from Rv1647 by 1aa, P2A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1833249 11809942 BCGMEX_1658 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171122.1 1832299 D 717522 CDS YP_005171123.1 378771390 11809943 1833256..1834062 1 NC_016804.1 putative transmembrane protein 1834062 11809943 BCGMEX_1659 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171123.1 1833256 D 717522 CDS YP_005171124.1 378771391 11809944 1834258..1835283 1 NC_016804.1 Differs from Rv1649 by 1aa, D276A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phenylalanyl-tRNA synthetase, subunit alpha 1835283 11809944 BCGMEX_1660 Mycobacterium bovis BCG str. Mexico phenylalanyl-tRNA synthetase, subunit alpha YP_005171124.1 1834258 D 717522 CDS YP_005171125.1 378771392 11809945 1835283..1837778 1 NC_016804.1 Differs from Rv1650 by 1aa, V212A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phenylalanyl-tRNA synthetase subunit beta chain 1837778 pheT 11809945 pheT Mycobacterium bovis BCG str. Mexico phenylalanyl-tRNA synthetase subunit beta chain YP_005171125.1 1835283 D 717522 CDS YP_005171126.1 378771393 11809946 complement(1837872..1840928) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, an in-frame insertion of 21 bp leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (1018 aa versus 1011 aa). Differs from Rv1651c by insertion of 7aa at position 152 and by 1aa, V179A in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 1840928 PE_PGRS30 11809946 PE_PGRS30 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171126.1 1837872 R 717522 CDS YP_005171127.1 378771394 11809947 1841122..1842180 1 NC_016804.1 N-acetyl-gamma-glutamyl-phosphate reductase 1842180 11809947 BCGMEX_1663 Mycobacterium bovis BCG str. Mexico N-acetyl-gamma-glutamyl-phosphate reductase YP_005171127.1 1841122 D 717522 CDS YP_005171128.1 378771395 11809948 1842177..1843391 1 NC_016804.1 Ornithine acetyltransferase/N-acetylglutamate synthase protein 1843391 argJ 11809948 argJ Mycobacterium bovis BCG str. Mexico Ornithine acetyltransferase/N-acetylglutamate synthase protein YP_005171128.1 1842177 D 717522 CDS YP_005171129.1 378771396 11809949 1843388..1844272 1 NC_016804.1 acetylglutamate kinase 1844272 argB 11809949 argB Mycobacterium bovis BCG str. Mexico acetylglutamate kinase YP_005171129.1 1843388 D 717522 CDS YP_005171130.1 378771397 11809950 1844269..1845471 1 NC_016804.1 acetylornithine aminotransferase 1845471 argD 11809950 argD Mycobacterium bovis BCG str. Mexico acetylornithine aminotransferase YP_005171130.1 1844269 D 717522 CDS YP_005171131.1 378771398 11809951 1845468..1846391 1 NC_016804.1 ornithine carbamoyltransferase 1846391 argF 11809951 argF Mycobacterium bovis BCG str. Mexico ornithine carbamoyltransferase YP_005171131.1 1845468 D 717522 CDS YP_005171132.1 378771399 11809952 1846388..1846900 1 NC_016804.1 Arginine repressor 1846900 argR 11809952 argR Mycobacterium bovis BCG str. Mexico Arginine repressor YP_005171132.1 1846388 D 717522 CDS YP_005171133.1 378771400 11809953 1846909..1848105 1 NC_016804.1 argininosuccinate synthase 1848105 argG 11809953 argG Mycobacterium bovis BCG str. Mexico argininosuccinate synthase YP_005171133.1 1846909 D 717522 CDS YP_005171134.1 378771401 11809954 1848185..1849597 1 NC_016804.1 argininosuccinate lyase 1849597 argH 11809954 argH Mycobacterium bovis BCG str. Mexico argininosuccinate lyase YP_005171134.1 1848185 D 717522 CDS YP_005171135.1 378771402 11809955 1849706..1850767 1 NC_016804.1 putative chalcone synthase 1850767 pks10 11809955 pks10 Mycobacterium bovis BCG str. Mexico putative chalcone synthase YP_005171135.1 1849706 D 717522 CDS YP_005171136.1 378771403 11809956 1850850..1857230 1 NC_016804.1 Differs from Rv1661 by 2aa, W670R, P1176S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyketide synthase 1857230 pks7 11809956 pks7 Mycobacterium bovis BCG str. Mexico putative polyketide synthase YP_005171136.1 1850850 D 717522 CDS YP_005171137.1 378771404 11809957 1857250..1862055 1 NC_016804.1 Differs from Rv1662 by 6aa, Y78D, deletion of V692, V807A, G1260R, T1356A, C1468Y, and from Mb1690 by 1aa, deletion of V692 in BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyketide synthase 1862055 pks8 11809957 pks8 Mycobacterium bovis BCG str. Mexico putative polyketide synthase YP_005171137.1 1857250 D 717522 CDS YP_005171138.1 378771405 11809958 1862055..1863563 1 NC_016804.1 polyketide synthase 1863563 pks17 11809958 pks17 Mycobacterium bovis BCG str. Mexico polyketide synthase YP_005171138.1 1862055 D 717522 CDS YP_005171139.1 378771406 11809959 1863569..1866622 1 NC_016804.1 Differs from Rv1664 by 2aa, T36A, P350A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyketide synthase 1866622 pks9 11809959 pks9 Mycobacterium bovis BCG str. Mexico putative polyketide synthase YP_005171139.1 1863569 D 717522 CDS YP_005171140.1 378771407 11809960 1866769..1867830 1 NC_016804.1 chalcone synthase 1867830 pks11 11809960 pks11 Mycobacterium bovis BCG str. Mexico chalcone synthase YP_005171140.1 1866769 D 717522 CDS YP_005171141.1 378771408 11809961 complement(1867813..1869105) 1 NC_016804.1 putative cytochrome P450 139 1869105 cyp139 11809961 cyp139 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 139 YP_005171141.1 1867813 R 717522 CDS YP_005171142.1 378771409 11809962 complement(1869120..1870895) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1668c and Rv1667c exist as 2 genes with a small overlap between them. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 10 bp insertion leads to a single product; Macrolide ABC transporter ATP-binding protein 1870895 11809962 BCGMEX_1678c Mycobacterium bovis BCG str. Mexico Macrolide ABC transporter ATP-binding protein YP_005171142.1 1869120 R 717522 CDS YP_005171143.1 378771410 11809963 1871278..1871640 1 NC_016804.1 hypothetical protein 1871640 11809963 BCGMEX_1679 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171143.1 1871278 D 717522 CDS YP_005171144.1 378771411 11809964 1871673..1872020 1 NC_016804.1 hypothetical protein 1872020 11809964 BCGMEX_1680 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171144.1 1871673 D 717522 CDS YP_005171145.1 378771412 11809965 1872028..1872420 1 NC_016804.1 hypothetical protein 1872420 11809965 BCGMEX_1681 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171145.1 1872028 D 717522 CDS YP_005171146.1 378771413 11809966 complement(1872429..1873760) 1 NC_016804.1 putative integral membrane transport protein 1873760 11809966 BCGMEX_1682c Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005171146.1 1872429 R 717522 CDS YP_005171147.1 378771414 11809967 complement(1873853..1874785) 1 NC_016804.1 hypothetical protein 1874785 11809967 BCGMEX_1683c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171147.1 1873853 R 717522 CDS YP_005171148.1 378771415 11809968 complement(1874813..1875469) 1 NC_016804.1 putative transcriptional regulatory protein 1875469 11809968 BCGMEX_1684c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005171148.1 1874813 R 717522 CDS YP_005171149.1 378771416 11809969 complement(1875794..1876528) 1 NC_016804.1 Differs from Rv1675c by 1aa, A59V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 1876528 11809969 BCGMEX_1685c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005171149.1 1875794 R 717522 CDS YP_005171150.1 378771417 11809970 1876600..1877304 1 NC_016804.1 hypothetical protein 1877304 11809970 BCGMEX_1686 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171150.1 1876600 D 717522 CDS YP_005171151.1 378771418 11809971 1877301..1877849 1 NC_016804.1 putative lipoprotein 1877849 dsbF 11809971 dsbF Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171151.1 1877301 D 717522 CDS YP_005171152.1 378771419 11809972 1877950..1878852 1 NC_016804.1 putative integral membrane protein 1878852 11809972 BCGMEX_1688 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171152.1 1877950 D 717522 CDS YP_005171153.1 378771420 11809973 1878852..1879973 1 NC_016804.1 putative Acyl-CoA dehydrogenase 1879973 fadE16 11809973 fadE16 Mycobacterium bovis BCG str. Mexico putative Acyl-CoA dehydrogenase YP_005171153.1 1878852 D 717522 CDS YP_005171154.1 378771421 11809974 1879982..1880806 1 NC_016804.1 Differs from Mb1707 by 1aa, A230G in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1880806 11809974 BCGMEX_1690 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171154.1 1879982 D 717522 CDS YP_005171155.1 378771422 11809975 1880803..1881795 1 NC_016804.1 putative molybdopterin biosynthesis protein 1881795 moeX 11809975 moeX Mycobacterium bovis BCG str. Mexico putative molybdopterin biosynthesis protein YP_005171155.1 1880803 D 717522 CDS YP_005171156.1 378771423 11809976 1881956..1882873 1 NC_016804.1 putative coiled-coil structural protein 1882873 11809976 BCGMEX_1692 Mycobacterium bovis BCG str. Mexico putative coiled-coil structural protein YP_005171156.1 1881956 D 717522 CDS YP_005171157.1 378771424 11809977 1883091..1886090 1 NC_016804.1 putative long-chain acyl-CoA synthase 1886090 11809977 BCGMEX_1693 Mycobacterium bovis BCG str. Mexico putative long-chain acyl-CoA synthase YP_005171157.1 1883091 D 717522 CDS YP_005171158.1 378771425 11809978 1886083..1886307 1 NC_016804.1 hypothetical protein 1886307 11809978 BCGMEX_1694 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171158.1 1886083 D 717522 CDS YP_005171159.1 378771426 11809979 complement(1886273..1886896) 1 NC_016804.1 hypothetical protein 1886896 11809979 BCGMEX_1695c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171159.1 1886273 R 717522 CDS YP_005171160.1 378771427 11809980 complement(1886898..1887578) 1 NC_016804.1 Differs from Rv1686c by 1aa, F20V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein ABC transporter 1887578 11809980 BCGMEX_1696c Mycobacterium bovis BCG str. Mexico putative integral membrane protein ABC transporter YP_005171160.1 1886898 R 717522 CDS YP_005171161.1 378771428 11809981 complement(1887650..1888417) 1 NC_016804.1 putative ATP-binding protein ABC transporter 1888417 11809981 BCGMEX_1697c Mycobacterium bovis BCG str. Mexico putative ATP-binding protein ABC transporter YP_005171161.1 1887650 R 717522 CDS YP_005171162.1 378771429 11809982 1888476..1889087 1 NC_016804.1 3-methyladenine DNA glycosylase 1889087 11809982 BCGMEX_1698 Mycobacterium bovis BCG str. Mexico 3-methyladenine DNA glycosylase YP_005171162.1 1888476 D 717522 CDS YP_005171163.1 378771430 11809983 1889099..1890373 1 NC_016804.1 tyrosyl-tRNA synthetase 1890373 tyrS 11809983 tyrS Mycobacterium bovis BCG str. Mexico tyrosyl-tRNA synthetase YP_005171163.1 1889099 D 717522 CDS YP_005171164.1 378771431 11809984 1891024..1891407 1 NC_016804.1 In Mycobacterium bovis, a 2 bp insertion at the 5' end, leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv and in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico (139 aa versus 127 aa); putative lipoprotein 1891407 lprJ 11809984 lprJ Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171164.1 1891024 D 717522 CDS YP_005171165.1 378771432 11809985 1891446..1892198 1 NC_016804.1 hypothetical protein 1892198 11809985 BCGMEX_1701 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171165.1 1891446 D 717522 CDS YP_005171166.1 378771433 11809986 1892195..1893256 1 NC_016804.1 putative phosphatase 1893256 11809986 BCGMEX_1702 Mycobacterium bovis BCG str. Mexico putative phosphatase YP_005171166.1 1892195 D 717522 CDS YP_005171167.1 378771434 11809987 1893253..1893429 1 NC_016804.1 hypothetical protein 1893429 11809987 BCGMEX_1703 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171167.1 1893253 D 717522 CDS YP_005171168.1 378771435 11809988 1893437..1894243 1 NC_016804.1 cytotoxin/hemolysin-like protein 1894243 tlyA 11809988 tlyA Mycobacterium bovis BCG str. Mexico cytotoxin/hemolysin-like protein YP_005171168.1 1893437 D 717522 CDS YP_005171169.1 378771436 11809989 1894243..1895166 1 NC_016804.1 inorganic polyphosphate/ATP-NAD kinase 1895166 ppnK 11809989 ppnK Mycobacterium bovis BCG str. Mexico inorganic polyphosphate/ATP-NAD kinase YP_005171169.1 1894243 D 717522 CDS YP_005171170.1 378771437 11809990 1895180..1896943 1 NC_016804.1 putative DNA repair protein 1896943 recN 11809990 recN Mycobacterium bovis BCG str. Mexico putative DNA repair protein YP_005171170.1 1895180 D 717522 CDS YP_005171171.1 378771438 11809991 1897039..1898220 1 NC_016804.1 hypothetical protein 1898220 11809991 BCGMEX_1707 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171171.1 1897039 D 717522 CDS YP_005171172.1 378771439 11809992 1898242..1899186 1 NC_016804.1 hypothetical protein 1899186 11809992 BCGMEX_1708 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171172.1 1898242 D 717522 CDS YP_005171173.1 378771440 11809993 1899326..1901086 1 NC_016804.1 CTP synthase 1901086 pyrG 11809993 pyrG Mycobacterium bovis BCG str. Mexico CTP synthase YP_005171173.1 1899326 D 717522 CDS YP_005171174.1 378771441 11809994 1901079..1901702 1 NC_016804.1 Differs from Mb1726 by 2aa, F43L, A202T in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1901702 11809994 BCGMEX_1710 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171174.1 1901079 D 717522 CDS YP_005171175.1 378771442 11809995 1901699..1902634 1 NC_016804.1 Site-specific tyrosine recombinase 1902634 xerD 11809995 xerD Mycobacterium bovis BCG str. Mexico Site-specific tyrosine recombinase YP_005171175.1 1901699 D 717522 CDS YP_005171176.1 378771443 11809996 complement(1902708..1904072) 1 NC_016804.1 hypothetical protein 1904072 11809996 BCGMEX_1712c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171176.1 1902708 R 717522 CDS YP_005171177.1 378771444 11809997 complement(1904627..1905217) 1 NC_016804.1 Differs from Rv1703c and Mb1729c by 1aa, S48G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative catechol-o-methyltransferase 1905217 11809997 BCGMEX_1713c Mycobacterium bovis BCG str. Mexico putative catechol-o-methyltransferase YP_005171177.1 1904627 R 717522 CDS YP_005171178.1 378771445 11809998 complement(1905282..1906952) 1 NC_016804.1 Differs from Rv1704c by 2aa, L93R, S122G, and from Mb1730c by 1aa, S122G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative D-serine/alanine/glycine transporter protein 1906952 cycA 11809998 cycA Mycobacterium bovis BCG str. Mexico putative D-serine/alanine/glycine transporter protein YP_005171178.1 1905282 R 717522 CDS YP_005171179.1 378771446 11809999 complement(1906993..1908150) 1 NC_016804.1 Differs from Rv1705c by 2aa, A2D, V313L, and from Mb1731c by 1aa, A2D in BCG Pasteur. Differs from Rv1705c by 1aa, V313L in BCG Tokyo and BCG Mexico; PPE family protein 1908150 PPE22 11809999 PPE22 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171179.1 1906993 R 717522 CDS YP_005171180.1 378771447 11810000 complement(1908190..1909374) 1 NC_016804.1 PPE family protein 1909374 PPE23 11810000 PPE23 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171180.1 1908190 R 717522 CDS YP_005171181.1 378771448 11810001 complement(1909978..1910145) 1 NC_016804.1 hypothetical protein 1910145 11810001 BCGMEX_1717c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171181.1 1909978 R 717522 CDS YP_005171182.1 378771449 11810002 1910378..1911838 1 NC_016804.1 Differs from Rv1707 by 1aa, Q438R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 1911838 11810002 BCGMEX_1718 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171182.1 1910378 D 717522 CDS YP_005171183.1 378771450 11810003 1911856..1912812 1 NC_016804.1 Differs from Rv1708 by 1a, a T56A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative initiation inhibitor protein 1912812 11810003 BCGMEX_1719 Mycobacterium bovis BCG str. Mexico putative initiation inhibitor protein YP_005171183.1 1911856 D 717522 CDS YP_005171184.1 378771451 11810004 1912809..1913645 1 NC_016804.1 hypothetical protein 1913645 11810004 BCGMEX_1720 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171184.1 1912809 D 717522 CDS YP_005171185.1 378771452 11810005 1913642..1914337 1 NC_016804.1 hypothetical protein 1914337 11810005 BCGMEX_1721 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171185.1 1913642 D 717522 CDS YP_005171186.1 378771453 11810006 1914334..1915098 1 NC_016804.1 hypothetical protein 1915098 11810006 BCGMEX_1722 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171186.1 1914334 D 717522 CDS YP_005171187.1 378771454 11810007 1915095..1915787 1 NC_016804.1 cytidylate kinase 1915787 cmk 11810007 cmk Mycobacterium bovis BCG str. Mexico cytidylate kinase YP_005171187.1 1915095 D 717522 CDS YP_005171188.1 378771455 11810008 1915784..1917175 1 NC_016804.1 GTP-binding protein 1917175 engA 11810008 engA Mycobacterium bovis BCG str. Mexico GTP-binding protein YP_005171188.1 1915784 D 717522 CDS YP_005171189.1 378771456 11810009 1917349..1918161 1 NC_016804.1 putative oxidoreductase 1918161 11810009 BCGMEX_1725 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005171189.1 1917349 D 717522 CDS YP_005171190.1 378771457 11810010 1918155..1919069 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, Rv1715/fadB3 exists as a single gene. In Mycobacterium bovis, a single base transition splits fadB3 into 2 parts, fadB3a and fadB3b; putative 3-hydroxybutyryl-CoA dehydrogenase 1919069 fadB3 11810010 fadB3 Mycobacterium bovis BCG str. Mexico putative 3-hydroxybutyryl-CoA dehydrogenase YP_005171190.1 1918155 D 717522 CDS YP_005171191.1 378771458 11810011 1919072..1919902 1 NC_016804.1 Differs from Rv1716 by 2aa, G178S, A276V in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1919902 11810011 BCGMEX_1727 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171191.1 1919072 D 717522 CDS YP_005171192.1 378771459 11810012 1919902..1920252 1 NC_016804.1 hypothetical protein 1920252 11810012 BCGMEX_1728 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171192.1 1919902 D 717522 CDS YP_005171193.1 378771460 11810013 1920305..1920928 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, exists as a single gene. In Mycobacterium bovis AF2122/97, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base deletion leads to a shorter product with a different COOH terminus; hypothetical protein 1920928 11810013 BCGMEX_1729 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171193.1 1920305 D 717522 CDS YP_005171194.1 378771461 11810014 1921136..1921915 1 NC_016804.1 putative transcriptional regulatory protein 1921915 11810014 BCGMEX_1730 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005171194.1 1921136 D 717522 CDS YP_005171195.1 378771462 11810016 complement(1922525..1922914) 1 NC_016804.1 hypothetical protein 1922914 11810016 BCGMEX_1731c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171195.1 1922525 R 717522 CDS YP_005171196.1 378771463 11810017 complement(1922911..1923138) 1 NC_016804.1 hypothetical protein 1923138 11810017 BCGMEX_1732c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171196.1 1922911 R 717522 CDS YP_005171197.1 378771464 11810018 1923356..1924840 1 NC_016804.1 Differs from Rv1722 by 1aa, M31V Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; biotin carboxylase 1924840 11810018 BCGMEX_1733 Mycobacterium bovis BCG str. Mexico biotin carboxylase YP_005171197.1 1923356 D 717522 CDS YP_005171198.1 378771465 11810019 1924837..1926084 1 NC_016804.1 putative hydrolase 1926084 11810019 BCGMEX_1734 Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005171198.1 1924837 D 717522 CDS YP_005171199.1 378771466 11810020 complement(1926127..1926546) 1 NC_016804.1 hypothetical protein 1926546 11810020 BCGMEX_1735c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171199.1 1926127 R 717522 CDS YP_005171200.1 378771467 11810021 complement(1926536..1927246) 1 NC_016804.1 hypothetical protein 1927246 11810021 BCGMEX_1736c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171200.1 1926536 R 717522 CDS YP_005171201.1 378771468 11810022 1927347..1928732 1 NC_016804.1 Differs from Rv1726 by 1aa, Y326H, and from Mb1755 by 1aa, A61P in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; putative oxidoreductase 1928732 11810022 BCGMEX_1737 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005171201.1 1927347 D 717522 CDS YP_005171202.1 378771469 11810023 1928765..1929334 1 NC_016804.1 Differs from Rv1727 and Mb1756 by 1aa, D22E in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1929334 11810023 BCGMEX_1738 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171202.1 1928765 D 717522 CDS YP_005171203.1 378771470 11810024 complement(1929359..1930129) 1 NC_016804.1 hypothetical protein 1930129 11810024 BCGMEX_1739c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171203.1 1929359 R 717522 CDS YP_005171204.1 378771471 11810025 complement(1930126..1931064) 1 NC_016804.1 hypothetical protein 1931064 11810025 BCGMEX_1740c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171204.1 1930126 R 717522 CDS YP_005171205.1 378771472 11810026 complement(1931130..1932683) 1 NC_016804.1 putative penicillin-binding protein 1932683 11810026 BCGMEX_1741c Mycobacterium bovis BCG str. Mexico putative penicillin-binding protein YP_005171205.1 1931130 R 717522 CDS YP_005171206.1 378771473 11810027 1933115..1934671 1 NC_016804.1 Succinic semialdehyde dehydrogenase 1934671 gabD2 11810027 gabD2 Mycobacterium bovis BCG str. Mexico Succinic semialdehyde dehydrogenase YP_005171206.1 1933115 D 717522 CDS YP_005171207.1 378771474 11810028 complement(1934681..1935229) 1 NC_016804.1 hypothetical protein 1935229 11810028 BCGMEX_1743c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171207.1 1934681 R 717522 CDS YP_005171208.1 378771475 11810029 complement(1935293..1935925) 1 NC_016804.1 Differs from Rv1733c by 1aa, H68Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 1935925 11810029 BCGMEX_1744c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171208.1 1935293 R 717522 CDS YP_005171209.1 378771476 11810030 complement(1936212..1936454) 1 NC_016804.1 Differs from Mb1763c by 1aa, T79A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1936454 11810030 BCGMEX_1745c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171209.1 1936212 R 717522 CDS YP_005171210.1 378771477 11810031 complement(1936729..1937226) 1 NC_016804.1 hypothetical protein 1937226 11810031 BCGMEX_1746c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171210.1 1936729 R 717522 CDS YP_005171211.1 378771478 11810032 complement(1937666..1939624) 1 NC_016804.1 Differs from Rv1736c by 2aa, H53D, G77D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative nitrate reductase 1939624 narX 11810032 narX Mycobacterium bovis BCG str. Mexico putative nitrate reductase YP_005171211.1 1937666 R 717522 CDS YP_005171212.1 378771479 11810033 complement(1939621..1940808) 1 NC_016804.1 putative nitrate/nitrite transporter 1940808 narK2 11810033 narK2 Mycobacterium bovis BCG str. Mexico putative nitrate/nitrite transporter YP_005171212.1 1939621 R 717522 CDS YP_005171213.1 378771480 11810034 1941095..1941379 1 NC_016804.1 hypothetical protein 1941379 11810034 BCGMEX_1749 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171213.1 1941095 D 717522 CDS YP_005171214.1 378771481 11810035 complement(1941393..1943075) 1 NC_016804.1 Differs from Rv1739c by 1aa, L134R in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative sulfate-transport transmembrane protein ABC transporter 1943075 11810035 BCGMEX_1750c Mycobacterium bovis BCG str. Mexico putative sulfate-transport transmembrane protein ABC transporter YP_005171214.1 1941393 R 717522 CDS YP_005171215.1 378771482 11810036 1943143..1943355 1 NC_016804.1 hypothetical protein 1943355 11810036 BCGMEX_1751 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171215.1 1943143 D 717522 CDS YP_005171216.1 378771483 11810037 1943355..1943603 1 NC_016804.1 Differs from Rv1741 by 1aa, T67K in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1943603 11810037 BCGMEX_1752 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171216.1 1943355 D 717522 CDS YP_005171217.1 378771484 11810038 1943684..1944349 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a single base insertion leads to shorter product with a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; hypothetical protein 1944349 11810038 BCGMEX_1753 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171217.1 1943684 D 717522 CDS YP_005171218.1 378771485 11810039 1944443..1946143 1 NC_016804.1 Differs from Mb1772 by 1aa, V56D in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane serine/threonine-protein kinase E 1946143 pknE 11810039 pknE Mycobacterium bovis BCG str. Mexico putative transmembrane serine/threonine-protein kinase E YP_005171218.1 1944443 D 717522 CDS YP_005171219.1 378771486 11810040 complement(1946428..1946829) 1 NC_016804.1 Differs from Rv1744c by 1aa, Q121R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1946829 11810040 BCGMEX_1755c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171219.1 1946428 R 717522 CDS YP_005171220.1 378771487 11810041 complement(1946900..1947430) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, truncation at the 3' end due to a single base tranversion, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (176 aa versus 203 aa). Differs from Mb1774c by 1aa, F48S in BCG Pasteur, BCG Tokyo and BCG Mexico; isopentenyl-diphosphate delta-isomerase 1947430 idi 11810041 idi Mycobacterium bovis BCG str. Mexico isopentenyl-diphosphate delta-isomerase YP_005171220.1 1946900 R 717522 CDS YP_005171221.1 378771488 11810042 1947577..1949007 1 NC_016804.1 Differs from Rv1746 by 1aa, T325A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; anchored-membrane serine/threonine-protein kinase 1949007 pknF 11810042 pknF Mycobacterium bovis BCG str. Mexico anchored-membrane serine/threonine-protein kinase YP_005171221.1 1947577 D 717522 CDS YP_005171222.1 378771489 11810043 1949069..1951666 1 NC_016804.1 putative transmembrane ATP-binding protein ABC transporter 1951666 11810043 BCGMEX_1758 Mycobacterium bovis BCG str. Mexico putative transmembrane ATP-binding protein ABC transporter YP_005171222.1 1949069 D 717522 CDS YP_005171223.1 378771490 11810044 1952039..1952770 1 NC_016804.1 hypothetical protein 1952770 11810044 BCGMEX_1759 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171223.1 1952039 D 717522 CDS YP_005171224.1 378771491 11810045 complement(1952767..1953324) 1 NC_016804.1 putative integral membrane protein 1953324 11810045 BCGMEX_1760c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171224.1 1952767 R 717522 CDS YP_005171225.1 378771492 11810046 complement(1953408..1955006) 1 NC_016804.1 acyl-CoA synthetase 1955006 fadD1 11810046 fadD1 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005171225.1 1953408 R 717522 CDS YP_005171226.1 378771493 11810047 1955060..1956442 1 NC_016804.1 Differs from Rv1751 by 2aa, T311M, L439V, and from Mb1780 by 1aa, T311M in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1956442 11810047 BCGMEX_1762 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171226.1 1955060 D 717522 CDS YP_005171227.1 378771494 11810048 1956569..1957018 1 NC_016804.1 hypothetical protein 1957018 11810048 BCGMEX_1763 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171227.1 1956569 D 717522 CDS YP_005171228.1 378771495 11810049 complement(1957053..1960133) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, PPE24 differs in the 26 aa tandem repeat region, two copies less (in-frame deletion of 156 bp), and in the 25 aa repeat region, 2 and one more copies (in-frame insertion of 150bp and 75bp), respectively, compared to their homolog in Mycobacterium tuberculosis strain H37Rv; PPE family protein 1960133 PPE24 11810049 PPE24 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171228.1 1957053 R 717522 CDS YP_005171229.1 378771496 11810050 complement(1960337..1962028) 1 NC_016804.1 Differs from Rv1754c and Mb1783c by 1aa, S546N in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1962028 11810050 BCGMEX_1765c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171229.1 1960337 R 717522 CDS YP_005171230.1 378771497 11810051 complement(1962212..1963756) 1 NC_016804.1 Truncated by RvD2 deletion (6804bp) in Mycobacterium tuberculosis strain H37Rv; putative phospholipase C 4 1963756 plcD 11810051 plcD Mycobacterium bovis BCG str. Mexico putative phospholipase C 4 YP_005171230.1 1962212 R 717522 CDS YP_005171231.1 378771498 11810052 complement(1963885..1965069) 1 NC_016804.1 No Equivalent in Mycobacterium tuberculosis strain H37Rv. Belongs to the RvD2 region; hypothetical protein 1965069 11810052 BCGMEX_1767c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171231.1 1963885 R 717522 CDS YP_005171232.1 378771499 11810053 1965219..1966358 1 NC_016804.1 No Equivalent in Mycobacterium tuberculosis strain H37Rv. Belongs to RvD2 region; putative sulfite oxidase 1966358 11810053 BCGMEX_1768 Mycobacterium bovis BCG str. Mexico putative sulfite oxidase YP_005171232.1 1965219 D 717522 CDS YP_005171233.1 378771500 11810054 1966559..1969396 1 NC_016804.1 No Equivalent in Mycobacterium tuberculosis strain H37Rv. Belongs to RvD2 region; putative transmembrane transport protein 1969396 mmpL14 11810054 mmpL14 Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005171233.1 1966559 D 717522 CDS YP_005171234.1 378771501 11810055 1969717..1970373 1 NC_016804.1 Belongs to the RvD2 region. In Mycobacterium tuberculosis strain H37Rv, Rv1758 is interrupted by IS6110 insertion element and the 5'-end is deleted; putative cutinase 1970373 cut1 11810055 cut1 Mycobacterium bovis BCG str. Mexico putative cutinase YP_005171234.1 1969717 D 717522 CDS YP_005171235.1 378771502 11810056 complement(1970640..1973048) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1759c exists as a single gene. In Mycobacterium bovis BCG Pasteur, Tokyo and BCG Mexico, and Mycobacterium bovis, a single base deletion splits wag22 into 2 parts, wag22a and wag22b. Differs from Mb1789c and Rv1759c by three deletions R129 replaced by AG, 5aa deletion at position 739 and 12aa deletion at position 777 making protein smaller (802 aa versus 820 aa) in BCG Pasteur and BCG Mexico. 5aa deletion at position 739 and 12aa deletion at position 777 making protein smaller (803 aa versus 820 aa) in BCG Tokyo.; PE-PGRS family protein (second part) 1973048 wag22b 11810056 wag22b Mycobacterium bovis BCG str. Mexico PE-PGRS family protein (second part) YP_005171235.1 1970640 R 717522 CDS YP_005171236.1 378771503 11810057 complement(1973045..1973329) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1759c exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, a single base deletion splits wag22 into 2 parts, wag22a and wag22b. Differs from Mb1789c and Rv1759c by three deletions R129 replaced by AG, 5aa deletion at position 739 and 12aa deletion at position 777 making protein smaller (802 aa versus 820 aa) in BCG Pasteur and BCG Mexico. 5aa deletion at position 739 and 12aa deletion at position 777 making protein smaller (803 aa versus 820 aa) in BCG Tokyo.; PE PGRS family protein 1973329 wag22a 11810057 wag22a Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005171236.1 1973045 R 717522 CDS YP_005171237.1 378771504 11810058 1973905..1975434 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Also differs from Rv1760 by 1aa, V219E; hypothetical protein 1975434 11810058 BCGMEX_1773 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171237.1 1973905 D 717522 CDS YP_005171238.1 378771505 11810059 complement(1975422..1975805) 1 NC_016804.1 hypothetical protein 1975805 11810059 BCGMEX_1774c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171238.1 1975422 R 717522 CDS YP_005171239.1 378771506 11810060 complement(1975805..1976593) 1 NC_016804.1 hypothetical protein 1976593 11810060 BCGMEX_1775c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171239.1 1975805 R 717522 CDS YP_005171240.1 378771507 11810061 complement(1976733..1977200) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv this region is occupied by IS6110 which interrupts the gene and appears to have deleted sequences downstream. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico, and Mycobacterium bovis, there is an 848bp sequence that has replaced a 121bp sequence; hypothetical protein 1977200 11810061 BCGMEX_1776c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171240.1 1976733 R 717522 CDS YP_005171241.1 378771508 11810062 complement(1977298..1977450) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv this region is occupied by IS6110 which appears to have deleted sequences downstream. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, there is an 848bp sequence that has replaced a 121bp sequence; hypothetical protein 1977450 11810062 BCGMEX_1777c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171241.1 1977298 R 717522 CDS YP_005171242.1 378771509 11810063 complement(1977611..1978867) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, deletion of 9068 bp (region of difference RD14), compared to Mycobacterium tuberculosis H37Rv, Mycobacterium bovis AF2122/97, BCG Tokyo and BCG Mexico, removes genes Rv1765A-Rv1772 and merges truncated genes Rv1773c and Rv1765c in BCG Pasteur. Mycobacterium bovis (Mb1794c) and BCG Tokyo have a longer products to its homolog in Mycobacterium tuberculosis H37Rv (Rv1765c, 418 aa versus 365 aa).; hypothetical protein 1978867 11810063 BCGMEX_1778c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171242.1 1977611 R 717522 CDS YP_005171243.1 378771510 11810064 complement(1979494..1979709) 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1975c) and Mycobavterium tuberculosis H37Rv (Rv1765A) in Mycobacterium bovis BCG Tokyo and BCG Mexico; hypothetical protein 1979709 11810064 BCGMEX_1779c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171243.1 1979494 R 717522 CDS YP_005171244.1 378771511 11810065 1980089..1980358 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1975A) and Mycobavterium tuberculosis H37Rv (Rv1766) in Mycobacterium bovis BCG Tokyo and BCG Mexico; transposase 1980358 11810065 BCGMEX_1780 Mycobacterium bovis BCG str. Mexico transposase YP_005171244.1 1980089 D 717522 CDS YP_005171245.1 378771512 11810066 1980426..1980785 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1796) and Mycobavterium tuberculosis H37Rv (Rv1767) in Mycobacterium bovis BCG Tokyo and BCG Mexico; hypothetical protein 1980785 11810066 BCGMEX_1781 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171245.1 1980426 D 717522 CDS YP_005171246.1 378771513 11810067 1980966..1982840 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium BCG Tokyo and BCG Mexico, a 18bp insertion, leads to a longer product compared to its homolog in Mycobacterium tuberculosis H37Rv (624 aa versus 618 aa).; PE-PGRS family protein 1982840 PE_PGRS31 11810067 PE_PGRS31 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171246.1 1980966 D 717522 CDS YP_005171247.1 378771514 11810068 1982996..1984240 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1798) and Mycobavterium tuberculosis H37Rv (Rv1769) in Mycobacterium bovis BCG Tokyo and BCG Mexico; hypothetical protein 1984240 11810068 BCGMEX_1783 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171247.1 1982996 D 717522 CDS YP_005171248.1 378771515 11810069 1984248..1985534 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1799) and Mycobavterium tuberculosis H37Rv (Rv1770) in Mycobacterium bovis BCG Tokyo and BCG Mexico; hypothetical protein 1985534 11810069 BCGMEX_1784 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171248.1 1984248 D 717522 CDS YP_005171249.1 378771516 11810070 1985531..1986817 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1800) and Mycobavterium tuberculosis H37Rv (Rv1771) in Mycobacterium bovis BCG Tokyo and BCG Mexico; Oxidoreductase 1986817 11810070 BCGMEX_1785 Mycobacterium bovis BCG str. Mexico Oxidoreductase YP_005171249.1 1985531 D 717522 CDS YP_005171250.1 378771517 11810071 1987006..1987317 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1801) and Mycobacterium tuberculosis H37Rv (Rv1772) in Mycobacterium bovis BCG Tokyo and BCG Mexico; hypothetical protein 1987317 11810071 BCGMEX_1786 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171250.1 1987006 D 717522 CDS YP_005171251.1 378771518 11810072 complement(1987390..1988136) 1 NC_016804.1 Equivalent to Mycobacterium bovis (Mb1802c) and Mycobacterium tuberculosis H37Rv (Rv1773c) in Mycobacterium bovis BCG Tokyo and BCG Mexico; transcriptional regulatory protein 1988136 11810072 BCGMEX_1787c Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein YP_005171251.1 1987390 R 717522 CDS YP_005171252.1 378771519 11810073 1988202..1989542 1 NC_016804.1 putative oxidoreductase 1989542 11810073 BCGMEX_1788 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005171252.1 1988202 D 717522 CDS YP_005171253.1 378771520 11810074 1989542..1990360 1 NC_016804.1 hypothetical protein 1990360 11810074 BCGMEX_1789 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171253.1 1989542 D 717522 CDS YP_005171254.1 378771521 11810075 complement(1990365..1990925) 1 NC_016804.1 transcriptional regulator 1990925 11810075 BCGMEX_1790c Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005171254.1 1990365 R 717522 CDS YP_005171255.1 378771522 11810076 1991026..1992330 1 NC_016804.1 Differs from Rv1777 by 1aa Q325H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytochrome P450 144 1992330 cyp144 11810076 cyp144 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 144 YP_005171255.1 1991026 D 717522 CDS YP_005171256.1 378771523 11810077 complement(1992451..1992900) 1 NC_016804.1 Differs from Mb1807c by 1aa T32R in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1992900 11810077 BCGMEX_1792c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171256.1 1992451 R 717522 CDS YP_005171257.1 378771524 11810078 complement(1993056..1994849) 1 NC_016804.1 putative integral membrane protein 1994849 11810078 BCGMEX_1793c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171257.1 1993056 R 717522 CDS YP_005171258.1 378771525 11810079 1995069..1995632 1 NC_016804.1 hypothetical protein 1995632 11810079 BCGMEX_1794 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171258.1 1995069 D 717522 CDS YP_005171259.1 378771526 11810080 complement(1995672..1997846) 1 NC_016804.1 Differs from Rv1781c and Mb1810c by 1aa, T12A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative 4-alpha-glucanotransferase 1997846 malQ 11810080 malQ Mycobacterium bovis BCG str. Mexico putative 4-alpha-glucanotransferase YP_005171259.1 1995672 R 717522 CDS YP_005171260.1 378771527 11810081 1998110..1999630 1 NC_016804.1 Differs from Rv1782 by 1aa H41R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 1999630 11810081 BCGMEX_1796 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171260.1 1998110 D 717522 CDS YP_005171261.1 378771528 11810082 1999627..2003802 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1783 and Rv1784 exist as 2 genes. In Mycobacterium bovis and in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transversion leads to a single product. Differs from Rv1783 and Mb1812 by 1aa, V692A in BCG Pasteur, similar to Rv1784 in BCG Pasteur, Tokyo and BCG Mexico; hypothetical protein 2003802 11810082 BCGMEX_1797 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171261.1 1999627 D 717522 CDS YP_005171262.1 378771529 11810083 complement(2003817..2004998) 1 NC_016804.1 putative Cytochrome P450 143 2004998 cyp143 11810083 cyp143 Mycobacterium bovis BCG str. Mexico putative Cytochrome P450 143 YP_005171262.1 2003817 R 717522 CDS YP_005171263.1 378771530 11810084 2005198..2005401 1 NC_016804.1 putative ferredoxin 2005401 11810084 BCGMEX_1799 Mycobacterium bovis BCG str. Mexico putative ferredoxin YP_005171263.1 2005198 D 717522 CDS YP_005171264.1 378771531 11810085 2005671..2006765 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur,BCG Tokyo and BCG Mexico, a 8 bp to 5 bp substitution, leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (364 aa versus 365 aa). similar to Mb1815; PPE family protein 2006765 PPE25 11810085 PPE25 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171264.1 2005671 D 717522 CDS YP_005171265.1 378771532 11810086 2006844..2007143 1 NC_016804.1 PE family protein 2007143 PE18 11810086 PE18 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171265.1 2006844 D 717522 CDS YP_005171266.1 378771533 11810087 2007157..2008338 1 NC_016804.1 Differs from Mb1817 by 1aa, S274A, similar to Rv1789 in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 2008338 PPE26 11810087 PPE26 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171266.1 2007157 D 717522 CDS YP_005171267.1 378771534 11810088 2008792..2009844 1 NC_016804.1 similar to Rv1790 differs from Mb1818 by 1aa, P190S in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 2009844 PPE27 11810088 PPE27 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171267.1 2008792 D 717522 CDS YP_005171268.1 378771535 11810089 2010271..2010570 1 NC_016804.1 PE family protein 2010570 PE19 11810089 PE19 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171268.1 2010271 D 717522 CDS YP_005171269.1 378771536 11810090 2010714..2011010 1 NC_016804.1 Differs from Rv1792 by 1aa Q48M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2011010 esxM 11810090 esxM Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171269.1 2010714 D 717522 CDS YP_005171270.1 378771537 11810091 2011061..2011345 1 NC_016804.1 putative ESAT-6 like protein 5 2011345 esxN 11810091 esxN Mycobacterium bovis BCG str. Mexico putative ESAT-6 like protein 5 YP_005171270.1 2011061 D 717522 CDS YP_005171271.1 378771538 11810092 2011433..2012335 1 NC_016804.1 hypothetical protein 2012335 11810092 BCGMEX_1807 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171271.1 2011433 D 717522 CDS YP_005171272.1 378771539 11810093 2012607..2014118 1 NC_016804.1 Differs from Mb1823 and Rv1795 by 1aa, T256A and D261G, respectively, in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2014118 11810093 BCGMEX_1808 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171272.1 2012607 D 717522 CDS YP_005171273.1 378771540 11810094 2014096..2015853 1 NC_016804.1 putative pro-rich protease 2015853 11810094 BCGMEX_1809 Mycobacterium bovis BCG str. Mexico putative pro-rich protease YP_005171273.1 2014096 D 717522 CDS YP_005171274.1 378771541 11810095 2015850..2017070 1 NC_016804.1 hypothetical protein 2017070 11810095 BCGMEX_1810 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171274.1 2015850 D 717522 CDS YP_005171275.1 378771542 11810096 2017067..2018899 1 NC_016804.1 hypothetical protein 2018899 11810096 BCGMEX_1811 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171275.1 2017067 D 717522 CDS YP_005171276.1 378771543 11810097 2019526..2019717 1 NC_016804.1 putative lipoprotein 2019717 lppT 11810097 lppT Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171276.1 2019526 D 717522 CDS YP_005171277.1 378771544 11810098 2019820..2021787 1 NC_016804.1 Differs from Rv1800 by 3aa, W144C, V253F, V432I, and from Mb1828 by 1aa, V432I in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 2021787 PPE28 11810098 PPE28 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171277.1 2019820 D 717522 CDS YP_005171278.1 378771545 11810099 2022368..2023639 1 NC_016804.1 PPE family protein 2023639 PPE29 11810099 PPE29 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171278.1 2022368 D 717522 CDS YP_005171279.1 378771546 11810100 2023751..2025142 1 NC_016804.1 PPE family protein 2025142 PPE30 11810100 PPE30 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171279.1 2023751 D 717522 CDS YP_005171280.1 378771547 11810101 complement(2025290..2026912) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS32 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, and BCG Tokyo, a frameshift due to a single base transition splits PE_PGRS32 into 2 parts, PE_PGRS32a and PE_PGRS32b; PE PGRS family protein 2026912 PE_PGRS32b 11810101 PE_PGRS32b Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005171280.1 2025290 R 717522 CDS YP_005171281.1 378771548 11810102 complement(2026946..2027209) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS32 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base transition splits PE_PGRS32 into 2 parts, PE_PGRS32a and PE_PGRS32b; PE-PGRS family protein 2027209 PE_PGRS32a 11810102 PE_PGRS32a Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171281.1 2026946 R 717522 CDS YP_005171282.1 378771549 11810103 complement(2027390..2027716) 1 NC_016804.1 hypothetical protein 2027716 11810103 BCGMEX_1818c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171282.1 2027390 R 717522 CDS YP_005171283.1 378771550 11810104 complement(2028054..2028401) 1 NC_016804.1 hypothetical protein 2028401 11810104 BCGMEX_1819c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171283.1 2028054 R 717522 CDS YP_005171284.1 378771551 11810105 2028439..2028738 1 NC_016804.1 PE family protein 2028738 PE20 11810105 PE20 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171284.1 2028439 D 717522 CDS YP_005171285.1 378771552 11810106 2028753..2029964 1 NC_016804.1 Differs from Rv1807 by 2aa, S223F, L234V. similar to Mb1836 in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 2029964 PPE31 11810106 PPE31 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171285.1 2028753 D 717522 CDS YP_005171286.1 378771553 11810107 2030288..2031517 1 NC_016804.1 Differs from Rv1808 by 1aa, A301G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 2031517 PPE32 11810107 PPE32 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171286.1 2030288 D 717522 CDS YP_005171287.1 378771554 11810108 2031649..2032212 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE33 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur,BCG Tokyo and BCG Mexico, a frameshift due to a single base transition splits PPE33 into 2 parts, PPE33a and PPE33b; PPE family protein 2032212 PPE33a 11810108 PPE33a Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171287.1 2031649 D 717522 CDS YP_005171288.1 378771555 11810110 2033300..2033656 1 NC_016804.1 hypothetical protein 2033656 11810110 BCGMEX_1825 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171288.1 2033300 D 717522 CDS YP_005171289.1 378771556 11810111 2033810..2034514 1 NC_016804.1 putative Mg2+ transport P-type atpase C MgtC 2034514 11810111 BCGMEX_1826 Mycobacterium bovis BCG str. Mexico putative Mg2+ transport P-type atpase C MgtC YP_005171289.1 2033810 D 717522 CDS YP_005171290.1 378771557 11810112 complement(2034524..2035726) 1 NC_016804.1 Differs from Rv1812c by 1aa, P30L in Mycobacteium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative dehydrogenase 2035726 11810112 BCGMEX_1827c Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005171290.1 2034524 R 717522 CDS YP_005171291.1 378771558 11810113 complement(2036048..2036479) 1 NC_016804.1 hypothetical protein 2036479 11810113 BCGMEX_1828c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171291.1 2036048 R 717522 CDS YP_005171292.1 378771559 11810114 2036888..2037790 1 NC_016804.1 membrane-bound C-5 sterol desaturase 2037790 erg3 11810114 erg3 Mycobacterium bovis BCG str. Mexico membrane-bound C-5 sterol desaturase YP_005171292.1 2036888 D 717522 CDS YP_005171293.1 378771560 11810115 2037895..2038560 1 NC_016804.1 Differs from Rv1815 by 1aa, F83I in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2038560 11810115 BCGMEX_1830 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171293.1 2037895 D 717522 CDS YP_005171294.1 378771561 11810116 2038623..2039327 1 NC_016804.1 putative transcriptional regulator 2039327 11810116 BCGMEX_1831 Mycobacterium bovis BCG str. Mexico putative transcriptional regulator YP_005171294.1 2038623 D 717522 CDS YP_005171295.1 378771562 11810117 2039808..2039888 1 NC_016804.1 hypothetical protein 2039888 11810117 BCGMEX_1832 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171295.1 2039808 D 717522 CDS YP_005171296.1 378771563 11810118 2039962..2041425 1 NC_016804.1 putative flavoprotein 2041425 11810118 BCGMEX_1833 Mycobacterium bovis BCG str. Mexico putative flavoprotein YP_005171296.1 2039962 D 717522 CDS YP_005171297.1 378771564 11810119 complement(2041545..2043050) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 9 bp insertion, leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (501 aa versus 498 aa). Differs from Rv1818c by 4aa, S233G, and deletion of 3aa near C-terminus. similar to Mb1849c; PE-PGRS family protein 2043050 PE_PGRS33 11810119 PE_PGRS33 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171297.1 2041545 R 717522 CDS YP_005171298.1 378771565 11810120 complement(2043185..2045104) 1 NC_016804.1 Differs from Rv1819c by 1aa, V603I in BCG Pasteur, BCG Tokyo and BCG Mexico; putative drugs-transport transmembrane, ABC transporter, ATP-binding protein 2045104 11810120 BCGMEX_1835c Mycobacterium bovis BCG str. Mexico putative drugs-transport transmembrane, ABC transporter, ATP-binding protein YP_005171298.1 2043185 R 717522 CDS YP_005171299.1 378771566 11810121 2045175..2046818 1 NC_016804.1 putative Acetolactate synthase 2046818 ilvG 11810121 ilvG Mycobacterium bovis BCG str. Mexico putative Acetolactate synthase YP_005171299.1 2045175 D 717522 CDS YP_005171300.1 378771567 11810122 2046833..2049259 1 NC_016804.1 protein translocase subunit 2049259 secA2 11810122 secA2 Mycobacterium bovis BCG str. Mexico protein translocase subunit YP_005171300.1 2046833 D 717522 CDS YP_005171301.1 378771568 11810123 2049456..2050085 1 NC_016804.1 putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2050085 pgsA2 11810123 pgsA2 Mycobacterium bovis BCG str. Mexico putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_005171301.1 2049456 D 717522 CDS YP_005171302.1 378771569 11810124 2050078..2051001 1 NC_016804.1 hypothetical protein 2051001 11810124 BCGMEX_1839 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171302.1 2050078 D 717522 CDS YP_005171303.1 378771570 11810125 2051030..2051395 1 NC_016804.1 hypothetical protein 2051395 11810125 BCGMEX_1840 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171303.1 2051030 D 717522 CDS YP_005171304.1 378771571 11810126 2051412..2052290 1 NC_016804.1 hypothetical protein 2052290 11810126 BCGMEX_1841 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171304.1 2051412 D 717522 CDS YP_005171305.1 378771572 11810127 2052328..2052732 1 NC_016804.1 Differs from Rv1826 by 1aa, A80E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; glycine cleavage system H protein 2052732 gcvH 11810127 gcvH Mycobacterium bovis BCG str. Mexico glycine cleavage system H protein YP_005171305.1 2052328 D 717522 CDS YP_005171306.1 378771573 11810128 2052972..2053460 1 NC_016804.1 hypothetical protein 2053460 cfp17 11810128 cfp17 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171306.1 2052972 D 717522 CDS YP_005171307.1 378771574 11810129 2053457..2054200 1 NC_016804.1 hypothetical protein 2054200 11810129 BCGMEX_1844 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171307.1 2053457 D 717522 CDS YP_005171308.1 378771575 11810130 2054319..2054813 1 NC_016804.1 Differs from Mb1860 by 1aa R93C in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2054813 11810130 BCGMEX_1845 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171308.1 2054319 D 717522 CDS YP_005171309.1 378771576 11810131 2055161..2055838 1 NC_016804.1 hypothetical protein 2055838 11810131 BCGMEX_1846 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171309.1 2055161 D 717522 CDS YP_005171310.1 378771577 11810132 2055891..2056148 1 NC_016804.1 hypothetical protein 2056148 11810132 BCGMEX_1847 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171310.1 2055891 D 717522 CDS YP_005171311.1 378771578 11810133 2056197..2059022 1 NC_016804.1 Differs from Rv1832 by 2aa, A215V, A448T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; glycine dehydrogenase 2059022 gcvB 11810133 gcvB Mycobacterium bovis BCG str. Mexico glycine dehydrogenase YP_005171311.1 2056197 D 717522 CDS YP_005171312.1 378771579 11810134 complement(2059249..2060109) 1 NC_016804.1 putative haloalkane dehalogenase 2060109 11810134 BCGMEX_1849c Mycobacterium bovis BCG str. Mexico putative haloalkane dehalogenase YP_005171312.1 2059249 R 717522 CDS YP_005171313.1 378771580 11810135 2060150..2061016 1 NC_016804.1 Differs from Mb1865 by 1aa, V272A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative hydrolase 2061016 11810135 BCGMEX_1850 Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005171313.1 2060150 D 717522 CDS YP_005171314.1 378771581 11810136 complement(2061021..2062907) 1 NC_016804.1 hypothetical protein 2062907 11810136 BCGMEX_1851c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171314.1 2061021 R 717522 CDS YP_005171315.1 378771582 11810137 complement(2062923..2064956) 1 NC_016804.1 Differs from Rv1836c by 2aa, C137R, H591R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2064956 11810137 BCGMEX_1852c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171315.1 2062923 R 717522 CDS YP_005171316.1 378771583 11810138 complement(2065076..2067301) 1 NC_016804.1 Malate synthase G 2067301 glcB 11810138 glcB Mycobacterium bovis BCG str. Mexico Malate synthase G YP_005171316.1 2065076 R 717522 CDS YP_005171317.1 378771584 11810139 complement(2067577..2067972) 1 NC_016804.1 hypothetical protein 2067972 11810139 BCGMEX_1854c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171317.1 2067577 R 717522 CDS YP_005171318.1 378771585 11810140 complement(2067969..2068232) 1 NC_016804.1 hypothetical protein 2068232 11810140 BCGMEX_1855c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171318.1 2067969 R 717522 CDS YP_005171319.1 378771586 11810142 complement(2069019..2069837) 1 NC_016804.1 In Mycobacterium bovis, an in-frame deletion of 147bp leads to a shorter protein compared to its homolog in Mycobacterium tuberculosis strain H37Rv (466 aa versus 518 aa). In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a deletion of 1bp, splits PPE34 into 2 parts, PPE34a and PPE34b; PE-PGRS family protein 2069837 PE_PGRS34a 11810142 PE_PGRS34a Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171319.1 2069019 R 717522 CDS YP_005171320.1 378771587 11810143 complement(2070000..2071049) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 12 bp in-frame insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (349 aa versus 345 aa); hypothetical protein 2071049 11810143 BCGMEX_1858c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171320.1 2070000 R 717522 CDS YP_005171321.1 378771588 11810144 complement(2071049..2072416) 1 NC_016804.1 Differs from Rv1842c by 1aa, S437L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2072416 11810144 BCGMEX_1859c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171321.1 2071049 R 717522 CDS YP_005171322.1 378771589 11810145 complement(2072590..2074029) 1 NC_016804.1 inosine-5-monophosphate dehydrogenase 2074029 guaB1 11810145 guaB1 Mycobacterium bovis BCG str. Mexico inosine-5-monophosphate dehydrogenase YP_005171322.1 2072590 R 717522 CDS YP_005171323.1 378771590 11810146 complement(2073395..2075452) 1 NC_016804.1 similar to Mb1875c, including frameshift at 3'end due to single base insertion, and extensive overlap with guaB1 in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico. In addition, differs from Rv1844c by 2 codon deletion after codon 70 in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 6-phosphogluconate dehydrogenase 2075452 gnd1 11810146 gnd1 Mycobacterium bovis BCG str. Mexico 6-phosphogluconate dehydrogenase YP_005171323.1 2073395 R 717522 CDS YP_005171324.1 378771591 11810147 complement(2075542..2076492) 1 NC_016804.1 Differs from Rv1845c and Mb1876c by 1aa, A222V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 2076492 11810147 BCGMEX_1862c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171324.1 2075542 R 717522 CDS YP_005171325.1 378771592 11810148 complement(2076507..2076923) 1 NC_016804.1 Differs from Rv1846c by 1aa, Y92D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; transcriptional regulator 2076923 11810148 BCGMEX_1863c Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005171325.1 2076507 R 717522 CDS YP_005171326.1 378771593 11810149 2077201..2077623 1 NC_016804.1 Differs from Rv1847 by 1aa, L90V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2077623 11810149 BCGMEX_1864 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171326.1 2077201 D 717522 CDS YP_005171327.1 378771594 11810150 2077672..2077974 1 NC_016804.1 urease subunit gamma 2077974 ureA 11810150 ureA Mycobacterium bovis BCG str. Mexico urease subunit gamma YP_005171327.1 2077672 D 717522 CDS YP_005171328.1 378771595 11810151 2077971..2078285 1 NC_016804.1 urease subunit beta 2078285 ureB 11810151 ureB Mycobacterium bovis BCG str. Mexico urease subunit beta YP_005171328.1 2077971 D 717522 CDS YP_005171329.1 378771596 11810152 2078285..2080018 1 NC_016804.1 urease subunit alpha 2080018 ureC 11810152 ureC Mycobacterium bovis BCG str. Mexico urease subunit alpha YP_005171329.1 2078285 D 717522 CDS YP_005171330.1 378771597 11810153 2080018..2080653 1 NC_016804.1 Differs from Rv1851 by 1aa, L34V in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; urease accessory protein UreF 2080653 ureF 11810153 ureF Mycobacterium bovis BCG str. Mexico urease accessory protein UreF YP_005171330.1 2080018 D 717522 CDS YP_005171331.1 378771598 11810154 2080664..2081338 1 NC_016804.1 urease accessory protein UreG 2081338 ureG 11810154 ureG Mycobacterium bovis BCG str. Mexico urease accessory protein UreG YP_005171331.1 2080664 D 717522 CDS YP_005171332.1 378771599 11810155 2081346..2081972 1 NC_016804.1 putative urease accessory protein 2081972 ureD 11810155 ureD Mycobacterium bovis BCG str. Mexico putative urease accessory protein YP_005171332.1 2081346 D 717522 CDS YP_005171333.1 378771600 11810156 complement(2081975..2083366) 1 NC_016804.1 Differs from Rv1854c by 1aa, R313G, and Mb1885c by 2aa, R284W, R313G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative NADH dehydrogenase 2083366 ndh 11810156 ndh Mycobacterium bovis BCG str. Mexico putative NADH dehydrogenase YP_005171333.1 2081975 R 717522 CDS YP_005171334.1 378771601 11810157 complement(2083507..2084430) 1 NC_016804.1 putative oxidoreductase 2084430 11810157 BCGMEX_1872c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005171334.1 2083507 R 717522 CDS YP_005171335.1 378771602 11810158 complement(2084469..2085146) 1 NC_016804.1 Differs from Rv1856c by 1aa, H185R in BCG Pasteur, BCG Tokyo and BCG Mexico; Oxidoreductase, short-chain dehydrogenase 2085146 11810158 BCGMEX_1873c Mycobacterium bovis BCG str. Mexico Oxidoreductase, short-chain dehydrogenase YP_005171335.1 2084469 R 717522 CDS YP_005171336.1 378771603 11810159 2085308..2086093 1 NC_016804.1 molybdate-binding protein 2086093 modA 11810159 modA Mycobacterium bovis BCG str. Mexico molybdate-binding protein YP_005171336.1 2085308 D 717522 CDS YP_005171337.1 378771604 11810160 2086096..2086890 1 NC_016804.1 molybdenum transport system permease protein 2086890 modB 11810160 modB Mycobacterium bovis BCG str. Mexico molybdenum transport system permease protein YP_005171337.1 2086096 D 717522 CDS YP_005171338.1 378771605 11810161 2086897..2088006 1 NC_016804.1 Differs from Rv1859 by 1aa, M313T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; molybdenum transport ATP-binding protein 2088006 modC 11810161 modC Mycobacterium bovis BCG str. Mexico molybdenum transport ATP-binding protein YP_005171338.1 2086897 D 717522 CDS YP_005171339.1 378771606 11810162 2088059..2089036 1 NC_016804.1 Differs from Rv1860 by 1aa, L136F in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; alanine and proline rich secreted protein 2089036 apa 11810162 apa Mycobacterium bovis BCG str. Mexico alanine and proline rich secreted protein YP_005171339.1 2088059 D 717522 CDS YP_005171340.1 378771607 11810163 2089488..2089793 1 NC_016804.1 transmembrane protein 2089793 11810163 BCGMEX_1878 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005171340.1 2089488 D 717522 CDS YP_005171341.1 378771608 11810164 2089868..2090908 1 NC_016804.1 putative alcohol dehydrogenase 2090908 adhA 11810164 adhA Mycobacterium bovis BCG str. Mexico putative alcohol dehydrogenase YP_005171341.1 2089868 D 717522 CDS YP_005171342.1 378771609 11810165 complement(2090915..2091685) 1 NC_016804.1 putative integral membrane protein 2091685 11810165 BCGMEX_1880c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171342.1 2090915 R 717522 CDS YP_005171343.1 378771610 11810166 complement(2091678..2092433) 1 NC_016804.1 hypothetical protein 2092433 11810166 BCGMEX_1881c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171343.1 2091678 R 717522 CDS YP_005171344.1 378771611 11810167 complement(2092430..2093290) 1 NC_016804.1 short-chain dehydrogenase 2093290 11810167 BCGMEX_1882c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005171344.1 2092430 R 717522 CDS YP_005171345.1 378771612 11810168 2093464..2095800 1 NC_016804.1 Differs from Rv1866 by 1aa, Q17E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2095800 11810168 BCGMEX_1883 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171345.1 2093464 D 717522 CDS YP_005171346.1 378771613 11810169 2096088..2097572 1 NC_016804.1 acetyl-CoA acetyltransferase 2097572 11810169 BCGMEX_1884 Mycobacterium bovis BCG str. Mexico acetyl-CoA acetyltransferase YP_005171346.1 2096088 D 717522 CDS YP_005171347.1 378771614 11810170 2097671..2099770 1 NC_016804.1 Differs from Rv1868 and Mb1899 by 1aa, G621D in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2099770 11810170 BCGMEX_1885 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171347.1 2097671 D 717522 CDS YP_005171348.1 378771615 11810171 complement(2099784..2101019) 1 NC_016804.1 Differs from Mb1900c and Rv1869c by 1aa, P4S in BCG Pasteur, BCG Tokyo and BCG Mexico; putative reductase 2101019 11810171 BCGMEX_1886c Mycobacterium bovis BCG str. Mexico putative reductase YP_005171348.1 2099784 R 717522 CDS YP_005171349.1 378771616 11810172 complement(2101086..2101754) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transversion and a single base transition lead to a slightly longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (222 aa versus 211 aa); hypothetical protein 2101754 11810172 BCGMEX_1887c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171349.1 2101086 R 717522 CDS YP_005171350.1 378771617 11810173 complement(2101819..2102208) 1 NC_016804.1 hypothetical protein 2102208 11810173 BCGMEX_1888c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171350.1 2101819 R 717522 CDS YP_005171351.1 378771618 11810174 complement(2102231..2103475) 1 NC_016804.1 Differs from Rv1872c by 2aa, A59G, A176V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative L-lactate dehydrogenase 2103475 lldD2 11810174 lldD2 Mycobacterium bovis BCG str. Mexico putative L-lactate dehydrogenase YP_005171351.1 2102231 R 717522 CDS YP_005171352.1 378771619 11810175 2103498..2103935 1 NC_016804.1 Differs from Mb1904 by 1aa, D102N in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2103935 11810175 BCGMEX_1890 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171352.1 2103498 D 717522 CDS YP_005171353.1 378771620 11810176 2104008..2104694 1 NC_016804.1 hypothetical protein 2104694 11810176 BCGMEX_1891 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171353.1 2104008 D 717522 CDS YP_005171354.1 378771621 11810177 2104705..2105148 1 NC_016804.1 hypothetical protein 2105148 11810177 BCGMEX_1892 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171354.1 2104705 D 717522 CDS YP_005171355.1 378771622 11810178 2105664..2106143 1 NC_016804.1 putative bacterioferritin 2106143 bfrA 11810178 bfrA Mycobacterium bovis BCG str. Mexico putative bacterioferritin YP_005171355.1 2105664 D 717522 CDS YP_005171356.1 378771623 11810179 2106228..2107763 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1877 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion, splits Rv1877 into 2 parts; putative integral membrane protein 2107763 11810179 BCGMEX_1894 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171356.1 2106228 D 717522 CDS YP_005171357.1 378771624 11810180 2107078..2108292 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1877 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion, splits Rv1877 into 2 parts; putative integral membrane protein 2108292 11810180 BCGMEX_1895 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171357.1 2107078 D 717522 CDS YP_005171358.1 378771625 11810181 2108347..2109699 1 NC_016804.1 similar to Rv1878, differs from Mb1910 by 1aa, A275T in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative glutamine synthetase 2109699 glnA3 11810181 glnA3 Mycobacterium bovis BCG str. Mexico putative glutamine synthetase YP_005171358.1 2108347 D 717522 CDS YP_005171359.1 378771626 11810182 2109702..2110838 1 NC_016804.1 hypothetical protein 2110838 11810182 BCGMEX_1897 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171359.1 2109702 D 717522 CDS YP_005171360.1 378771627 11810183 complement(2110866..2112182) 1 NC_016804.1 putative cytochrome P450 140 2112182 cyp140 11810183 cyp140 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 140 YP_005171360.1 2110866 R 717522 CDS YP_005171361.1 378771628 11810184 complement(2112232..2112654) 1 NC_016804.1 hypothetical protein 2112654 lppE 11810184 lppE Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171361.1 2112232 R 717522 CDS YP_005171362.1 378771629 11810185 complement(2112695..2113528) 1 NC_016804.1 putative short-chain type dehydrogenase/reductase 2113528 11810185 BCGMEX_1900c Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005171362.1 2112695 R 717522 CDS YP_005171363.1 378771630 11810186 complement(2113556..2114032) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 15 bp in-frame insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (158 aa versus 153 aa); hypothetical protein 2114032 11810186 BCGMEX_1901c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171363.1 2113556 R 717522 CDS YP_005171364.1 378771631 11810187 complement(2114071..2114601) 1 NC_016804.1 putative resuscitation-promoting factor 2114601 rpfC 11810187 rpfC Mycobacterium bovis BCG str. Mexico putative resuscitation-promoting factor YP_005171364.1 2114071 R 717522 CDS YP_005171365.1 378771632 11810188 complement(2114613..2115212) 1 NC_016804.1 periplasmic chorismate mutase I 2115212 11810188 BCGMEX_1903c Mycobacterium bovis BCG str. Mexico periplasmic chorismate mutase I YP_005171365.1 2114613 R 717522 CDS YP_005171366.1 378771633 11810189 complement(2115230..2116207) 1 NC_016804.1 Differs from Rv1886c and Mb1918c by 1aa, L140F; Secreted antigen 85-B 2116207 fbpB 11810189 fbpB Mycobacterium bovis BCG str. Mexico Secreted antigen 85-B YP_005171366.1 2115230 R 717522 CDS YP_005171367.1 378771634 11810190 2116598..2117740 1 NC_016804.1 Differs from Rv1887 and Mb1919 by 1aa, C121Y in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2117740 11810190 BCGMEX_1905 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171367.1 2116598 D 717522 CDS YP_005171368.1 378771635 11810191 complement(2117710..2118429) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 10 bp insertion leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis H37Rv (239 aa versus 186 aa); putative transmembrane protein 2118429 11810191 BCGMEX_1906c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171368.1 2117710 R 717522 CDS YP_005171369.1 378771636 11810192 complement(2118794..2118967) 1 NC_016804.1 hypothetical protein 2118967 11810192 BCGMEX_1907c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171369.1 2118794 R 717522 CDS YP_005171370.1 378771637 11810193 complement(2119011..2119367) 1 NC_016804.1 methyltransferase 2119367 11810193 BCGMEX_1908c Mycobacterium bovis BCG str. Mexico methyltransferase YP_005171370.1 2119011 R 717522 CDS YP_005171371.1 378771638 11810194 complement(2119426..2120037) 1 NC_016804.1 hypothetical protein 2120037 11810194 BCGMEX_1909c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171371.1 2119426 R 717522 CDS YP_005171372.1 378771639 11810195 2120091..2120498 1 NC_016804.1 hypothetical protein 2120498 11810195 BCGMEX_1910 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171372.1 2120091 D 717522 CDS YP_005171373.1 378771640 11810196 2120515..2120826 1 NC_016804.1 hypothetical protein 2120826 11810196 BCGMEX_1911 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171373.1 2120515 D 717522 CDS YP_005171374.1 378771641 11810197 2120836..2121054 1 NC_016804.1 hypothetical protein 2121054 11810197 BCGMEX_1912 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171374.1 2120836 D 717522 CDS YP_005171375.1 378771642 11810198 complement(2121089..2122219) 1 NC_016804.1 hypothetical protein 2122219 11810198 BCGMEX_1913c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171375.1 2121089 R 717522 CDS YP_005171376.1 378771643 11810199 2122871..2123194 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1895 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, two frameshifts due to a single base deletion and a single base insertion, consecutively, splits Rv1895 into 2 main parts, Mb1928 and Mb1929; putative dehydrogenase 2123194 11810199 BCGMEX_1914 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005171376.1 2122871 D 717522 CDS YP_005171377.1 378771644 11810200 2123191..2123895 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv1895 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, two frameshifts due to a single base deletion and a single base insertion, consecutively, splits Rv1895 into 2 main parts, Mb1928 and Mb1929; putative dehydrogenase 2123895 11810200 BCGMEX_1915 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005171377.1 2123191 D 717522 CDS YP_005171378.1 378771645 11810201 complement(2123885..2124796) 1 NC_016804.1 putative S-adenosyl-L-methionine-dependent methyltransferase 2124796 11810201 BCGMEX_1916c Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005171378.1 2123885 R 717522 CDS YP_005171379.1 378771646 11810202 complement(2124801..2125232) 1 NC_016804.1 Differs from Rv1897c and Mb1932c by 1aa, G60D in BCG Pasteur, BCG Tokyo and BCG Mexico; D-tyrosyl-tRNA deacylase 2125232 11810202 BCGMEX_1917c Mycobacterium bovis BCG str. Mexico D-tyrosyl-tRNA deacylase YP_005171379.1 2124801 R 717522 CDS YP_005171380.1 378771647 11810203 2125290..2125598 1 NC_016804.1 hypothetical protein 2125598 11810203 BCGMEX_1918 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171380.1 2125290 D 717522 CDS YP_005171381.1 378771648 11810204 complement(2125564..2126640) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur,BCG Tokyo and BCG Mexico, a 45 bp in-frame insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (358 aa versus 343 aa); putative lipoprotein 2126640 lppD 11810204 lppD Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171381.1 2125564 R 717522 CDS YP_005171382.1 378771649 11810205 complement(2126640..2128028) 1 NC_016804.1 Differs from Rv1900c and Mb1935c by 1aa, M204I and R170Q, respectively, in BCG Pasteur, BCG Tokyo and BCG Mexico; putative lignin peroxidase 2128028 lipJ 11810205 lipJ Mycobacterium bovis BCG str. Mexico putative lignin peroxidase YP_005171382.1 2126640 R 717522 CDS YP_005171383.1 378771650 11810206 2128057..2129349 1 NC_016804.1 Competence/damage-inducible protein A 2129349 cinA 11810206 cinA Mycobacterium bovis BCG str. Mexico Competence/damage-inducible protein A YP_005171383.1 2128057 D 717522 CDS YP_005171384.1 378771651 11810207 complement(2129401..2130669) 1 NC_016804.1 putative sialic acid-transport integral membrane protein 2130669 nanT 11810207 nanT Mycobacterium bovis BCG str. Mexico putative sialic acid-transport integral membrane protein YP_005171384.1 2129401 R 717522 CDS YP_005171385.1 378771652 11810208 2130759..2131163 1 NC_016804.1 hypothetical protein 2131163 11810208 BCGMEX_1923 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171385.1 2130759 D 717522 CDS YP_005171386.1 378771653 11810209 2131349..2131780 1 NC_016804.1 Differs from Rv1904 by 1aa, M130T in BCG Pasteur, BCG Tokyo and BCG Mexico; anti-sigma factor antagonist 2131780 11810209 BCGMEX_1924 Mycobacterium bovis BCG str. Mexico anti-sigma factor antagonist YP_005171386.1 2131349 D 717522 CDS YP_005171387.1 378771654 11810210 complement(2131828..2132790) 1 NC_016804.1 Differs from Rv1905c by 1aa, T240P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, and BCG Tokyo; putative D-amino-acid oxidase 2132790 aao 11810210 aao Mycobacterium bovis BCG str. Mexico putative D-amino-acid oxidase YP_005171387.1 2131828 R 717522 CDS YP_005171388.1 378771655 11810211 complement(2132820..2133290) 1 NC_016804.1 hypothetical protein 2133290 11810211 BCGMEX_1926c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171388.1 2132820 R 717522 CDS YP_005171389.1 378771656 11810212 complement(2133630..2134277) 1 NC_016804.1 hypothetical protein 2134277 11810212 BCGMEX_1927c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171389.1 2133630 R 717522 CDS YP_005171390.1 378771657 11810213 complement(2134284..2136506) 1 NC_016804.1 Differs from Rv1908c by 1aa, L463R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; catalase-peroxidase-peroxynitritase T 2136506 katG 11810213 katG Mycobacterium bovis BCG str. Mexico catalase-peroxidase-peroxynitritase T YP_005171390.1 2134284 R 717522 CDS YP_005171391.1 378771658 11810214 complement(2136544..2136996) 1 NC_016804.1 Differs from Rv1909c and Mb1944c by 1aa, V46A in BCG Pasteur, BCG Tokyo and BCG Mexico; Ferric uptake regulation protein 2136996 furA 11810214 furA Mycobacterium bovis BCG str. Mexico Ferric uptake regulation protein YP_005171391.1 2136544 R 717522 CDS YP_005171392.1 378771659 11810215 complement(2137101..2137694) 1 NC_016804.1 hypothetical protein 2137694 11810215 BCGMEX_1930c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171392.1 2137101 R 717522 CDS YP_005171393.1 378771660 11810216 complement(2137777..2138382) 1 NC_016804.1 putative lipoprotein 2138382 lppC 11810216 lppC Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171393.1 2137777 R 717522 CDS YP_005171394.1 378771661 11810217 complement(2138482..2139486) 1 NC_016804.1 Differs from Rv1912c by 1aa, G328D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 2139486 fadB5 11810217 fadB5 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005171394.1 2138482 R 717522 CDS YP_005171395.1 378771662 11810218 2139586..2140338 1 NC_016804.1 Differs from Rv1913 and Mb1948 by 1aa, C7R in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2140338 11810218 BCGMEX_1933 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171395.1 2139586 D 717522 CDS YP_005171396.1 378771663 11810219 complement(2140316..2140723) 1 NC_016804.1 hypothetical protein 2140723 11810219 BCGMEX_1934c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171396.1 2140316 R 717522 CDS YP_005171397.1 378771664 11810220 2140858..2143158 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, aceAa and aceAb exist as 2 genes. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base insertion leads to a single product; putative isocitrate lyase 2143158 aceA 11810220 aceA Mycobacterium bovis BCG str. Mexico putative isocitrate lyase YP_005171397.1 2140858 D 717522 CDS YP_005171398.1 378771665 11810221 complement(2143328..2148835) 1 NC_016804.1 Equivalent to Mb1951c and Rv1917c but differs by several in-frame insertion and deletion events. Differs from Mb1951c by 69 bp insertion, 69 bp deletion and 225 bp deletion. Differs from Rv1917c by deletions of 12 and 138 bp, insertions of 552 and 150 bp, and substitution of 52bp by 628 bp in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 2148835 PPE34 11810221 PPE34 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171398.1 2143328 R 717522 CDS YP_005171399.1 378771666 11810223 complement(2150260..2152137) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE35 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion splits PPE35 into 2 parts, PPE35a and PPE35b. Differs from Mb1953c by 1aa, F565V in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico.; PPE family protein 2152137 PPE35a 11810223 PPE35a Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171399.1 2150260 R 717522 CDS YP_005171400.1 378771667 11810224 complement(2152586..2153050) 1 NC_016804.1 hypothetical protein 2153050 11810224 BCGMEX_1939c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171400.1 2152586 R 717522 CDS YP_005171401.1 378771668 11810225 2153148..2154011 1 NC_016804.1 Differs from Rv1920 by 1aa, I130M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2154011 11810225 BCGMEX_1940 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171401.1 2153148 D 717522 CDS YP_005171402.1 378771669 11810226 complement(2154049..2155320) 1 NC_016804.1 hypothetical protein 2155320 lppF 11810226 lppF Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171402.1 2154049 R 717522 CDS YP_005171403.1 378771670 11810227 2155592..2156707 1 NC_016804.1 putative lipoprotein 2156707 11810227 BCGMEX_1942 Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171403.1 2155592 D 717522 CDS YP_005171404.1 378771671 11810228 2156698..2158038 1 NC_016804.1 Differs from Rv1923 by 2aa, D73G, N181D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipase 2158038 lipD 11810228 lipD Mycobacterium bovis BCG str. Mexico putative lipase YP_005171404.1 2156698 D 717522 CDS YP_005171405.1 378771672 11810229 complement(2158075..2158455) 1 NC_016804.1 hypothetical protein 2158455 11810229 BCGMEX_1944c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171405.1 2158075 R 717522 CDS YP_005171406.1 378771673 11810230 2158612..2160474 1 NC_016804.1 Differs from Rv1925 by 1aa, L190M in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative Acyl-CoA ligase 2160474 fadD31 11810230 fadD31 Mycobacterium bovis BCG str. Mexico putative Acyl-CoA ligase YP_005171406.1 2158612 D 717522 CDS YP_005171407.1 378771674 11810231 complement(2160482..2160961) 1 NC_016804.1 immunogenic protein MPT63 2160961 mpt63 11810231 mpt63 Mycobacterium bovis BCG str. Mexico immunogenic protein MPT63 YP_005171407.1 2160482 R 717522 CDS YP_005171408.1 378771675 11810232 2161198..2161971 1 NC_016804.1 hypothetical protein 2161971 11810232 BCGMEX_1947 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171408.1 2161198 D 717522 CDS YP_005171409.1 378771676 11810233 complement(2161975..2162742) 1 NC_016804.1 putative short-chain type dehydrogenase/reductase 2162742 11810233 BCGMEX_1948c Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005171409.1 2161975 R 717522 CDS YP_005171410.1 378771677 11810234 complement(2162787..2163431) 1 NC_016804.1 hypothetical protein 2163431 11810234 BCGMEX_1949c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171410.1 2162787 R 717522 CDS YP_005171411.1 378771678 11810235 complement(2163443..2163967) 1 NC_016804.1 hypothetical protein 2163967 11810235 BCGMEX_1950c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171411.1 2163443 R 717522 CDS YP_005171412.1 378771679 11810236 complement(2163985..2164764) 1 NC_016804.1 transcriptional regulator 2164764 11810236 BCGMEX_1951c Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005171412.1 2163985 R 717522 CDS YP_005171413.1 378771680 11810237 2164897..2165394 1 NC_016804.1 Thiol peroxidase 2165394 tpx 11810237 tpx Mycobacterium bovis BCG str. Mexico Thiol peroxidase YP_005171413.1 2164897 D 717522 CDS YP_005171414.1 378771681 11810238 complement(2165391..2166482) 1 NC_016804.1 putative acyl-CoA dehydrogenase 2166482 fadE18 11810238 fadE18 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005171414.1 2165391 R 717522 CDS YP_005171415.1 378771682 11810239 complement(2166484..2167713) 1 NC_016804.1 putative acyl-CoA dehydrogenase 2167713 fadE17 11810239 fadE17 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005171415.1 2166484 R 717522 CDS YP_005171416.1 378771683 11810240 complement(2167728..2168684) 1 NC_016804.1 enoyl-CoA hydratase 2168684 echA13 11810240 echA13 Mycobacterium bovis BCG str. Mexico enoyl-CoA hydratase YP_005171416.1 2167728 R 717522 CDS YP_005171417.1 378771684 11810241 2168909..2170018 1 NC_016804.1 monooxygenase component A 2170018 11810241 BCGMEX_1956 Mycobacterium bovis BCG str. Mexico monooxygenase component A YP_005171417.1 2168909 D 717522 CDS YP_005171418.1 378771685 11810242 2170021..2172540 1 NC_016804.1 Differs from Rv1937 by 1aa, P587A in Mycobacterium bovis BCG Mexico; putative oxygenase 2172540 11810242 BCGMEX_1957 Mycobacterium bovis BCG str. Mexico putative oxygenase YP_005171418.1 2170021 D 717522 CDS YP_005171419.1 378771686 11810243 2172552..2173622 1 NC_016804.1 putative epoxide hydrolase 2173622 ephB 11810243 ephB Mycobacterium bovis BCG str. Mexico putative epoxide hydrolase YP_005171419.1 2172552 D 717522 CDS YP_005171420.1 378771687 11810244 2173619..2174134 1 NC_016804.1 In Mycobacterium bovis, a single base deletion leads to a longer product with a different COOH part compared to its homologs in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico (244 aa versus 171 aa); putative oxidoreductase 2174134 11810244 BCGMEX_1959 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005171420.1 2173619 D 717522 CDS YP_005171421.1 378771688 11810245 2174131..2175192 1 NC_016804.1 3,4-dihydroxy-2-butanone 4-phosphate synthase 2175192 ribA1 11810245 ribA1 Mycobacterium bovis BCG str. Mexico 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_005171421.1 2174131 D 717522 CDS YP_005171422.1 378771689 11810246 2175189..2175959 1 NC_016804.1 putative short-chain type dehydrogenase/reductase 2175959 11810246 BCGMEX_1961 Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005171422.1 2175189 D 717522 CDS YP_005171423.1 378771690 11810247 complement(2176169..2176498) 1 NC_016804.1 hypothetical protein 2176498 11810247 BCGMEX_1962c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171423.1 2176169 R 717522 CDS YP_005171424.1 378771691 11810248 complement(2176495..2176872) 1 NC_016804.1 hypothetical protein 2176872 11810248 BCGMEX_1963c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171424.1 2176495 R 717522 CDS YP_005171425.1 378771692 11810249 complement(2176869..2177459) 1 NC_016804.1 Differs from Rv1944c and Mb1979c by 2aa, E4D, A5T, due to 2 bp substitution ta-cc in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2177459 11810249 BCGMEX_1964c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171425.1 2176869 R 717522 CDS YP_005171426.1 378771693 11810250 2177514..2178878 1 NC_016804.1 Differs from Mb1980 and Rv1945 by substitutions of 44, 29, 2, 10 and 34 bp, or 44, 29, 4, 2, 10 and 34 bp, respectively. Corresponding to 10 aa from Rv1945, L242V, N264H, A267G, F268L, A271G, K285R, I291V, N328H, H417K and P426A, and to 9 aa from Mb1980, N264H, A267G, F268L, A271G, K285R, I291V, N328H, H417K and P426A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2178878 11810250 BCGMEX_1965 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171426.1 2177514 D 717522 CDS YP_005171427.1 378771694 11810251 complement(2179033..2179485) 1 NC_016804.1 Differs from Rv1946c by 1aa, T98A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2179485 lppG 11810251 lppG Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171427.1 2179033 R 717522 CDS YP_005171428.1 378771695 11810252 2179549..2179950 1 NC_016804.1 hypothetical protein 2179950 11810252 BCGMEX_1967 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171428.1 2179549 D 717522 CDS YP_005171429.1 378771696 11810253 complement(2180239..2180589) 1 NC_016804.1 Differs from Rv1948c by 1aa, R5G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2180589 11810253 BCGMEX_1968c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171429.1 2180239 R 717522 CDS YP_005171430.1 378771697 11810254 complement(2180600..2181502) 1 NC_016804.1 Differs from Rv1949c by 1aa, L188F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2181502 11810254 BCGMEX_1969c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171430.1 2180600 R 717522 CDS YP_005171431.1 378771698 11810255 complement(2181523..2181714) 1 NC_016804.1 hypothetical protein 2181714 11810255 BCGMEX_1970c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171431.1 2181523 R 717522 CDS YP_005171432.1 378771699 11810256 complement(2181715..2182011) 1 NC_016804.1 hypothetical protein 2182011 11810256 BCGMEX_1971c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171432.1 2181715 R 717522 CDS YP_005171433.1 378771700 11810257 2182251..2182466 1 NC_016804.1 hypothetical protein 2182466 11810257 BCGMEX_1972 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171433.1 2182251 D 717522 CDS YP_005171434.1 378771701 11810258 2182463..2182774 1 NC_016804.1 hypothetical protein 2182774 11810258 BCGMEX_1973 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171434.1 2182463 D 717522 CDS YP_005171435.1 378771702 11810259 complement(2182748..2183269) 1 NC_016804.1 Differs from Rv1954c by 1aa, R150H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2183269 11810259 BCGMEX_1974c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171435.1 2182748 R 717522 CDS YP_005171436.1 378771703 11810260 2183109..2183621 1 NC_016804.1 hypothetical protein 2183621 11810260 BCGMEX_1975 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171436.1 2183109 D 717522 CDS YP_005171437.1 378771704 11810261 2183663..2184112 1 NC_016804.1 putative transciptional regulatory protein 2184112 11810261 BCGMEX_1976 Mycobacterium bovis BCG str. Mexico putative transciptional regulatory protein YP_005171437.1 2183663 D 717522 CDS YP_005171438.1 378771705 11810262 2184109..2184654 1 NC_016804.1 hypothetical protein 2184654 11810262 BCGMEX_1977 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171438.1 2184109 D 717522 CDS YP_005171439.1 378771706 11810263 complement(2184543..2185157) 1 NC_016804.1 hypothetical protein 2185157 11810263 BCGMEX_1978c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171439.1 2184543 R 717522 CDS YP_005171440.1 378771707 11810264 complement(2185206..2185502) 1 NC_016804.1 putative plasmid stabilization protein ParE 2185502 11810264 BCGMEX_1979c Mycobacterium bovis BCG str. Mexico putative plasmid stabilization protein ParE YP_005171440.1 2185206 R 717522 CDS YP_005171441.1 378771708 11810265 complement(2185499..2185750) 1 NC_016804.1 hypothetical protein 2185750 11810265 BCGMEX_1980c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171441.1 2185499 R 717522 CDS YP_005171442.1 378771709 11810266 2185737..2186231 1 NC_016804.1 hypothetical protein 2186231 11810266 BCGMEX_1981 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171442.1 2185737 D 717522 CDS YP_005171443.1 378771710 11810267 complement(2186391..2186798) 1 NC_016804.1 hypothetical protein 2186798 11810267 BCGMEX_1982c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171443.1 2186391 R 717522 CDS YP_005171444.1 378771711 11810268 complement(2186802..2187074) 1 NC_016804.1 hypothetical protein 2187074 11810268 BCGMEX_1983c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171444.1 2186802 R 717522 CDS YP_005171445.1 378771712 11810269 complement(2187107..2188327) 1 NC_016804.1 TetR-family transcriptional repressor mce3R 2188327 11810269 BCGMEX_1984c Mycobacterium bovis BCG str. Mexico TetR-family transcriptional repressor mce3R YP_005171445.1 2187107 R 717522 CDS YP_005171446.1 378771713 11810270 2189226..2189630 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur,BCG Tokyo and BCG Mexico, a large deletion of 12719 bp (RD7) leads to the loss of the COOH part of Rv1964|yrbE3A, the entire mce3 operon and the following genes up to Rv1978, compared to Mycobacterium tuberculosis strain H37Rv. Follow by a second deletion of 10287bp, RD2 region (only in Mycobacterium bovis BCG Pasteur and BCG Mexico), which removes genes Rv1979c-Rv1787 and merges truncated part of Rv1978 and Rv1988 compared to Mycobacterium tuberculosis strain H37Rv; putative integral membrane protein 2189630 yrbE3A 11810270 yrbE3A Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171446.1 2189226 D 717522 CDS YP_005171447.1 378771714 11810271 2189715..2190239 1 NC_016804.1 putative methyltransferase 2190239 11810271 BCGMEX_1986 Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005171447.1 2189715 D 717522 CDS YP_005171448.1 378771715 11810272 complement(2190759..2191319) 1 NC_016804.1 hypothetical protein 2191319 11810272 BCGMEX_1987c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171448.1 2190759 R 717522 CDS YP_005171449.1 378771716 11810273 complement(2191316..2191657) 1 NC_016804.1 transcriptional regulator 2191657 11810273 BCGMEX_1988c Mycobacterium bovis BCG str. Mexico transcriptional regulator YP_005171449.1 2191316 R 717522 CDS YP_005171450.1 378771717 11810274 complement(2191901..2192236) 1 NC_016804.1 putative dehydrogenase 2192236 11810274 BCGMEX_1989c Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005171450.1 2191901 R 717522 CDS YP_005171451.1 378771718 11810275 complement(2192325..2192666) 1 NC_016804.1 hypothetical protein 2192666 11810275 BCGMEX_1990c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171451.1 2192325 R 717522 CDS YP_005171452.1 378771719 11810276 complement(2193011..2195326) 1 NC_016804.1 putative cation-transporting P-type ATPase G 2195326 ctpG 11810276 ctpG Mycobacterium bovis BCG str. Mexico putative cation-transporting P-type ATPase G YP_005171452.1 2193011 R 717522 CDS YP_005171453.1 378771720 11810277 complement(2195323..2195595) 1 NC_016804.1 hypothetical protein 2195595 11810277 BCGMEX_1992c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171453.1 2195323 R 717522 CDS YP_005171454.1 378771721 11810278 complement(2195648..2196004) 1 NC_016804.1 ArsR family transcriptional regulator 2196004 11810278 BCGMEX_1993c Mycobacterium bovis BCG str. Mexico ArsR family transcriptional regulator YP_005171454.1 2195648 R 717522 CDS YP_005171455.1 378771722 11810279 2196161..2196928 1 NC_016804.1 hypothetical protein 2196928 11810279 BCGMEX_1994 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171455.1 2196161 D 717522 CDS YP_005171456.1 378771723 11810280 2197024..2197977 1 NC_016804.1 Universal stress protein family 2197977 11810280 BCGMEX_1995 Mycobacterium bovis BCG str. Mexico Universal stress protein family YP_005171456.1 2197024 D 717522 CDS YP_005171457.1 378771724 11810281 2198179..2200896 1 NC_016804.1 Differs from Rv1997 and Mb2020 by 1aa, D138E in BCG Pasteur, BCG Tokyo and BCG Mexico; putative metal cation transporter P-type atpase A 2200896 ctpF 11810281 ctpF Mycobacterium bovis BCG str. Mexico putative metal cation transporter P-type atpase A YP_005171457.1 2198179 D 717522 CDS YP_005171458.1 378771725 11810282 complement(2200965..2201741) 1 NC_016804.1 Differs from Rv1998c by 1aa, R230S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2201741 11810282 BCGMEX_1997c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171458.1 2200965 R 717522 CDS YP_005171459.1 378771726 11810283 complement(2201836..2203158) 1 NC_016804.1 putative transporter 2203158 11810283 BCGMEX_1998c Mycobacterium bovis BCG str. Mexico putative transporter YP_005171459.1 2201836 R 717522 CDS YP_005171460.1 378771727 11810284 2203229..2204842 1 NC_016804.1 hypothetical protein 2204842 11810284 BCGMEX_1999 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171460.1 2203229 D 717522 CDS YP_005171461.1 378771728 11810285 2204852..2205604 1 NC_016804.1 Differs from Rv2001 by 1aa, H113R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2205604 11810285 BCGMEX_2000 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171461.1 2204852 D 717522 CDS YP_005171462.1 378771729 11810286 2205680..2206462 1 NC_016804.1 putative 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 2206462 fabG3 11810286 fabG3 Mycobacterium bovis BCG str. Mexico putative 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase YP_005171462.1 2205680 D 717522 CDS YP_005171463.1 378771730 11810287 complement(2206583..2207440) 1 NC_016804.1 hypothetical protein 2207440 11810287 BCGMEX_2002c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171463.1 2206583 R 717522 CDS YP_005171464.1 378771731 11810288 complement(2207498..2208994) 1 NC_016804.1 hypothetical protein 2208994 11810288 BCGMEX_2003c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171464.1 2207498 R 717522 CDS YP_005171465.1 378771732 11810289 complement(2209016..2209903) 1 NC_016804.1 hypothetical protein 2209903 11810289 BCGMEX_2004c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171465.1 2209016 R 717522 CDS YP_005171466.1 378771733 11810290 2210022..2214005 1 NC_016804.1 Differs from Rv2006 and Mb2029 by 1aa, S80G and L1245P, respectively, in BCG Pasteur, BCG Tokyo and BCG Mexico; putative trehalose-6-phosphate phosphatase 2214005 otsB1 11810290 otsB1 Mycobacterium bovis BCG str. Mexico putative trehalose-6-phosphate phosphatase YP_005171466.1 2210022 D 717522 CDS YP_005171467.1 378771734 11810291 complement(2214104..2214448) 1 NC_016804.1 putative ferredoxin 2214448 fdxA 11810291 fdxA Mycobacterium bovis BCG str. Mexico putative ferredoxin YP_005171467.1 2214104 R 717522 CDS YP_005171468.1 378771735 11810292 complement(2214637..2215962) 1 NC_016804.1 hypothetical protein 2215962 11810292 BCGMEX_2007c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171468.1 2214637 R 717522 CDS YP_005171469.1 378771736 11810293 2216050..2216292 1 NC_016804.1 hypothetical protein 2216292 11810293 BCGMEX_2008 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171469.1 2216050 D 717522 CDS YP_005171470.1 378771737 11810294 2216293..2216691 1 NC_016804.1 hypothetical protein 2216691 11810294 BCGMEX_2009 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171470.1 2216293 D 717522 CDS YP_005171471.1 378771738 11810295 complement(2216874..2217305) 1 NC_016804.1 hypothetical protein 2217305 11810295 BCGMEX_2010c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171471.1 2216874 R 717522 CDS YP_005171472.1 378771739 11810296 2217346..2217840 1 NC_016804.1 hypothetical protein 2217840 11810296 BCGMEX_2011 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171472.1 2217346 D 717522 CDS YP_005171473.1 378771740 11810297 2217837..2218085 1 NC_016804.1 hypothetical protein 2218085 11810297 BCGMEX_2012 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171473.1 2217837 D 717522 CDS YP_005171474.1 378771741 11810298 2218544..2219161 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transition at the 5' start, leads to a longer product with a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (206 aa versus 159 aa); putative transposase 2219161 11810298 BCGMEX_2013 Mycobacterium bovis BCG str. Mexico putative transposase YP_005171474.1 2218544 D 717522 CDS YP_005171475.1 378771742 11810299 2219115..2219705 1 NC_016804.1 similar to Mb2037 including extra 5 aa at C-terminus compared to Rv2014 in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 2219705 11810299 BCGMEX_2014 Mycobacterium bovis BCG str. Mexico putative transposase YP_005171475.1 2219115 D 717522 CDS YP_005171476.1 378771743 11810300 complement(2219833..2221089) 1 NC_016804.1 Differs from Mb2038c by 1aa S59L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2221089 11810300 BCGMEX_2015c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171476.1 2219833 R 717522 CDS YP_005171477.1 378771744 11810301 2221443..2222018 1 NC_016804.1 hypothetical protein 2222018 11810301 BCGMEX_2016 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171477.1 2221443 D 717522 CDS YP_005171478.1 378771745 11810302 2222015..2223055 1 NC_016804.1 Differs from Rv2017 by 1aa, E262A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative regulatory protein 2223055 11810302 BCGMEX_2017 Mycobacterium bovis BCG str. Mexico putative regulatory protein YP_005171478.1 2222015 D 717522 CDS YP_005171479.1 378771746 11810303 2223297..2224016 1 NC_016804.1 Differs from Rv2018 by 1aa, G116D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2224016 11810303 BCGMEX_2018 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171479.1 2223297 D 717522 CDS YP_005171480.1 378771747 11810304 2224006..2224422 1 NC_016804.1 hypothetical protein 2224422 11810304 BCGMEX_2019 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171480.1 2224006 D 717522 CDS YP_005171481.1 378771748 11810305 complement(2224438..2224737) 1 NC_016804.1 hypothetical protein 2224737 11810305 BCGMEX_2020c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171481.1 2224438 R 717522 CDS YP_005171482.1 378771749 11810306 complement(2224822..2225127) 1 NC_016804.1 putative transcriptional regulator 2225127 11810306 BCGMEX_2021c Mycobacterium bovis BCG str. Mexico putative transcriptional regulator YP_005171482.1 2224822 R 717522 CDS YP_005171483.1 378771750 11810307 complement(2225136..2225741) 1 NC_016804.1 hypothetical protein 2225741 11810307 BCGMEX_2022c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171483.1 2225136 R 717522 CDS YP_005171484.1 378771751 11810308 complement(2225766..2226125) 1 NC_016804.1 hypothetical protein 2226125 11810308 BCGMEX_2023c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171484.1 2225766 R 717522 CDS YP_005171485.1 378771752 11810309 complement(2226285..2226938) 1 NC_016804.1 Belongs to the RvD1 region. Absent in Mycobacterium tuberculosis strain H37Rv; hypothetical protein 2226938 11810309 BCGMEX_2024c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171485.1 2226285 R 717522 CDS YP_005171486.1 378771753 11810310 complement(2226914..2227150) 1 NC_016804.1 hypothetical protein 2227150 11810310 BCGMEX_2025c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171486.1 2226914 R 717522 CDS YP_005171487.1 378771754 11810311 complement(2227357..2228253) 1 NC_016804.1 Belongs to the RvD1 region. Absent in Mycobacterium tuberculosis strain H37Rv. Differs from Mb2048c by 1aa, E139K in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2228253 11810311 BCGMEX_2026c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171487.1 2227357 R 717522 CDS YP_005171488.1 378771755 11810312 complement(2228437..2233257) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, a large deletion region (RvD1) exists in between Rv2023 and Rv2024. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 5000 bp insertion at this region results in Mb2049c being a much larger product with a different COOH part (1606 aa versus 515 aa), and in 2 extra genes, Mb2046c and Mb2047c. Differs from N-terminal part of Rv2024c (truncated by RvD1) by 3aa, R47W, G154D, C289R and Mb2049c by 1aa, F341V in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2233257 11810312 BCGMEX_2027c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171488.1 2228437 R 717522 CDS YP_005171489.1 378771756 11810313 complement(2233767..2234765) 1 NC_016804.1 cation efflux system protein 2234765 11810313 BCGMEX_2028c Mycobacterium bovis BCG str. Mexico cation efflux system protein YP_005171489.1 2233767 R 717522 CDS YP_005171490.1 378771757 11810314 complement(2234880..2235764) 1 NC_016804.1 hypothetical protein 2235764 11810314 BCGMEX_2029c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171490.1 2234880 R 717522 CDS YP_005171491.1 378771758 11810315 complement(2235804..2237525) 1 NC_016804.1 Differs from Rv2027c by 1aa, V15L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; histidine kinase response regulator 2237525 11810315 BCGMEX_2030c Mycobacterium bovis BCG str. Mexico histidine kinase response regulator YP_005171491.1 2235804 R 717522 CDS YP_005171492.1 378771759 11810316 complement(2237586..2238425) 1 NC_016804.1 hypothetical protein 2238425 11810316 BCGMEX_2031c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171492.1 2237586 R 717522 CDS YP_005171493.1 378771760 11810317 complement(2238422..2239441) 1 NC_016804.1 putative phosphofructokinase 2239441 pfkB 11810317 pfkB Mycobacterium bovis BCG str. Mexico putative phosphofructokinase YP_005171493.1 2238422 R 717522 CDS YP_005171494.1 378771761 11810318 complement(2239458..2241503) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, Rv2030c exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base deletion splits Rv2030c into 2 parts, Mb2055c and Mb2056c; hypothetical protein 2241503 11810318 BCGMEX_2033c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171494.1 2239458 R 717522 CDS YP_005171495.1 378771762 11810319 complement(2241515..2241949) 1 NC_016804.1 heat shock protein 2241949 hspX 11810319 hspX Mycobacterium bovis BCG str. Mexico heat shock protein YP_005171495.1 2241515 R 717522 CDS YP_005171496.1 378771763 11810320 2242146..2243141 1 NC_016804.1 Differs from Rv2032 by 1aa, L318P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2243141 11810320 BCGMEX_2035 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171496.1 2242146 D 717522 CDS YP_005171497.1 378771764 11810321 complement(2243257..2244099) 1 NC_016804.1 hypothetical protein 2244099 11810321 BCGMEX_2036c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171497.1 2243257 R 717522 CDS YP_005171498.1 378771765 11810322 2244311..2244634 1 NC_016804.1 putative ArsR-type repressor protein 2244634 11810322 BCGMEX_2037 Mycobacterium bovis BCG str. Mexico putative ArsR-type repressor protein YP_005171498.1 2244311 D 717522 CDS YP_005171499.1 378771766 11810323 2244631..2245119 1 NC_016804.1 hypothetical protein 2245119 11810323 BCGMEX_2038 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171499.1 2244631 D 717522 CDS YP_005171500.1 378771767 11810324 2245116..2245757 1 NC_016804.1 Differs from Rv2036 by 1aa, V93A due to 2bp substitution in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2245757 11810324 BCGMEX_2039 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171500.1 2245116 D 717522 CDS YP_005171501.1 378771768 11810325 complement(2245764..2246738) 1 NC_016804.1 Differs from Rv2037c by 1aa, Y312C in Mycobacterium tuberclosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 2246738 11810325 BCGMEX_2040c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171501.1 2245764 R 717522 CDS YP_005171502.1 378771769 11810326 complement(2246740..2247813) 1 NC_016804.1 putative sugar-transport ATP-binding protein ABC transporter 2247813 11810326 BCGMEX_2041c Mycobacterium bovis BCG str. Mexico putative sugar-transport ATP-binding protein ABC transporter YP_005171502.1 2246740 R 717522 CDS YP_005171503.1 378771770 11810327 complement(2247816..2248658) 1 NC_016804.1 Differs from Rv2039c by 1aa, F131V in Mycobacterium tuberclosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative sugar-transport integral membrane protein ABC transporter 2248658 11810327 BCGMEX_2042c Mycobacterium bovis BCG str. Mexico putative sugar-transport integral membrane protein ABC transporter YP_005171503.1 2247816 R 717522 CDS YP_005171504.1 378771771 11810328 complement(2248645..2249547) 1 NC_016804.1 putative sugar-transport integral membrane protein ABC transporter 2249547 11810328 BCGMEX_2043c Mycobacterium bovis BCG str. Mexico putative sugar-transport integral membrane protein ABC transporter YP_005171504.1 2248645 R 717522 CDS YP_005171505.1 378771772 11810329 complement(2249544..2250863) 1 NC_016804.1 Differs from Mb2067c by 1aa, A122V in BCG Pasteur and BCG Mexico; putative sugar-binding lipoprotein 2250863 11810329 BCGMEX_2044c Mycobacterium bovis BCG str. Mexico putative sugar-binding lipoprotein YP_005171505.1 2249544 R 717522 CDS YP_005171506.1 378771773 11810330 complement(2250901..2251698) 1 NC_016804.1 hypothetical protein 2251698 11810330 BCGMEX_2045c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171506.1 2250901 R 717522 CDS YP_005171507.1 378771774 11810331 complement(2251698..2252258) 1 NC_016804.1 Differs from Rv2043c by 1aa, D57H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Pyrazinamidase/Nicotinamidase 2252258 pncA 11810331 pncA Mycobacterium bovis BCG str. Mexico Pyrazinamidase/Nicotinamidase YP_005171507.1 2251698 R 717522 CDS YP_005171508.1 378771775 11810332 complement(2252299..2252616) 1 NC_016804.1 hypothetical protein 2252616 11810332 BCGMEX_2047c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171508.1 2252299 R 717522 CDS YP_005171509.1 378771776 11810333 complement(2252702..2254237) 1 NC_016804.1 putative carboxylesterase 2254237 lipT 11810333 lipT Mycobacterium bovis BCG str. Mexico putative carboxylesterase YP_005171509.1 2252702 R 717522 CDS YP_005171510.1 378771777 11810334 2254286..2254942 1 NC_016804.1 Differs from Rv2046 by 1aa, P17S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2254942 lppI 11810334 lppI Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171510.1 2254286 D 717522 CDS YP_005171511.1 378771778 11810335 complement(2254979..2257543) 1 NC_016804.1 hypothetical protein 2257543 11810335 BCGMEX_2050c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171511.1 2254979 R 717522 CDS YP_005171512.1 378771779 11810336 complement(2257548..2270003) 1 NC_016804.1 Differs from Mb2074c and Rv2048c in several positions due to various substitutions, transitions and transversions in BCG Pasteur,BCG Tokyo and BCG Mexico; polyketide synthase 2270003 pks12 11810336 pks12 Mycobacterium bovis BCG str. Mexico polyketide synthase YP_005171512.1 2257548 R 717522 CDS YP_005171513.1 378771780 11810337 complement(2270310..2270534) 1 NC_016804.1 hypothetical protein 2270534 11810337 BCGMEX_2052c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171513.1 2270310 R 717522 CDS YP_005171514.1 378771781 11810338 2270838..2271173 1 NC_016804.1 hypothetical protein 2271173 11810338 BCGMEX_2053 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171514.1 2270838 D 717522 CDS YP_005171515.1 378771782 11810339 complement(2271148..2273772) 1 NC_016804.1 polyprenol-monophosphomannose synthase 2273772 ppm1 11810339 ppm1 Mycobacterium bovis BCG str. Mexico polyprenol-monophosphomannose synthase YP_005171515.1 2271148 R 717522 CDS YP_005171516.1 378771783 11810340 complement(2273930..2275534) 1 NC_016804.1 hypothetical protein 2275534 11810340 BCGMEX_2055c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171516.1 2273930 R 717522 CDS YP_005171517.1 378771784 11810341 complement(2275539..2276066) 1 NC_016804.1 putative transmembrane protein 2276066 fxsA 11810341 fxsA Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171517.1 2275539 R 717522 CDS YP_005171518.1 378771785 11810342 2276142..2276855 1 NC_016804.1 hypothetical protein 2276855 11810342 BCGMEX_2057 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171518.1 2276142 D 717522 CDS YP_005171519.1 378771786 11810343 complement(2277104..2277370) 1 NC_016804.1 30S ribosomal protein S18 2277370 rpsR2 11810343 rpsR2 Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S18 YP_005171519.1 2277104 R 717522 CDS YP_005171520.1 378771787 11810344 complement(2277371..2277676) 1 NC_016804.1 30S ribosomal protein S14 2277676 rpsN2 11810344 rpsN2 Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S14 YP_005171520.1 2277371 R 717522 CDS YP_005171521.1 378771788 11810345 complement(2277678..2277842) 1 NC_016804.1 50S ribosomal protein L33 2277842 rpmG1 11810345 rpmG1 Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L33 YP_005171521.1 2277678 R 717522 CDS YP_005171522.1 378771789 11810346 complement(2277842..2278078) 1 NC_016804.1 50S ribosomal protein L28 2278078 rpmB2 11810346 rpmB2 Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L28 YP_005171522.1 2277842 R 717522 CDS YP_005171523.1 378771790 11810347 2278191..2279726 1 NC_016804.1 hypothetical protein 2279726 11810347 BCGMEX_2062 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171523.1 2278191 D 717522 CDS YP_005171524.1 378771791 11810348 complement(2279698..2280102) 1 NC_016804.1 hypothetical protein 2280102 11810348 BCGMEX_2063c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171524.1 2279698 R 717522 CDS YP_005171525.1 378771792 11810349 complement(2280186..2283770) 1 NC_016804.1 Differs from Rv2062c by 2aa, A75V, C688R and from Mb2088c by 1aa, C688R in BCG Pasteur, BCG Tokyo and BCG Mexico; putative component of cobalt chelatase involved in B12 biosynthesis 2283770 cobN 11810349 cobN Mycobacterium bovis BCG str. Mexico putative component of cobalt chelatase involved in B12 biosynthesis YP_005171525.1 2280186 R 717522 CDS YP_005171526.1 378771793 11810350 2283848..2284081 1 NC_016804.1 DNA-binding protein, CopG family 2284081 11810350 BCGMEX_2065 Mycobacterium bovis BCG str. Mexico DNA-binding protein, CopG family YP_005171526.1 2283848 D 717522 CDS YP_005171527.1 378771794 11810351 2284074..2284484 1 NC_016804.1 hypothetical protein 2284484 11810351 BCGMEX_2066 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171527.1 2284074 D 717522 CDS YP_005171528.1 378771795 11810352 2284468..2285559 1 NC_016804.1 putative cobalamin biosynthesis protein 2285559 cobG 11810352 cobG Mycobacterium bovis BCG str. Mexico putative cobalamin biosynthesis protein YP_005171528.1 2284468 D 717522 CDS YP_005171529.1 378771796 11810353 2285569..2286195 1 NC_016804.1 Cobalt-precorrin-8x methylmutase 2286195 cobH 11810353 cobH Mycobacterium bovis BCG str. Mexico Cobalt-precorrin-8x methylmutase YP_005171529.1 2285569 D 717522 CDS YP_005171530.1 378771797 11810354 2286192..2287718 1 NC_016804.1 putative CobI-CobJ fusion protein (cobalt-precorrin-2 C20-methyltransferase/ Cobalt-precorrin-3b C17-methyltransferase) 2287718 cobI 11810354 cobI Mycobacterium bovis BCG str. Mexico putative CobI-CobJ fusion protein (cobalt-precorrin-2 C20-methyltransferase/ Cobalt-precorrin-3b C17-methyltransferase) YP_005171530.1 2286192 D 717522 CDS YP_005171531.1 378771798 11810355 complement(2287664..2288887) 1 NC_016804.1 hypothetical protein 2288887 11810355 BCGMEX_2070c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171531.1 2287664 R 717522 CDS YP_005171532.1 378771799 11810356 complement(2288903..2289826) 1 NC_016804.1 beta-lactamase class A 2289826 blaC 11810356 blaC Mycobacterium bovis BCG str. Mexico beta-lactamase class A YP_005171532.1 2288903 R 717522 CDS YP_005171533.1 378771800 11810357 2289961..2290518 1 NC_016804.1 RNA polymerase sigma factor 2290518 sigC 11810357 sigC Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005171533.1 2289961 D 717522 CDS YP_005171534.1 378771801 11810358 complement(2290508..2291203) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base insertion leads to a shorter product with a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (231 aa versus 244 aa); Cobalt-precorrin-6x reductase 2291203 cobK 11810358 cobK Mycobacterium bovis BCG str. Mexico Cobalt-precorrin-6x reductase YP_005171534.1 2290508 R 717522 CDS YP_005171535.1 378771802 11810359 complement(2291240..2291995) 1 NC_016804.1 Differs from Rv2071c by 1aa, M145I in BCG Pasteur, BCG Tokyo and BCG Mexico; putative cobalt-precorrin-4 C11-methyltransferase 2291995 cobM 11810359 cobM Mycobacterium bovis BCG str. Mexico putative cobalt-precorrin-4 C11-methyltransferase YP_005171535.1 2291240 R 717522 CDS YP_005171536.1 378771803 11810360 complement(2291992..2292876) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a large 2029 bp deletion (RD9) leads to the loss of the NH2 part of cobL, the entire Rv2073 and Rv2074, and the COOH part of Mb2100c. In addition, while cobL exists as a single gene in Mycobacterium tuberculosis strain H37Rv, in Mycobacterium bovis a frameshift due to a single base insertion splits cobL into 2 parts, cobLa and cobLb; putative cobalt-precorrin-6y methyltransferase 2292876 cobLb 11810360 cobLb Mycobacterium bovis BCG str. Mexico putative cobalt-precorrin-6y methyltransferase YP_005171536.1 2291992 R 717522 CDS YP_005171537.1 378771804 11810361 complement(2292818..2293006) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a large 2029 bp deletion (RD9) leads to the loss of the NH2 part of cobL, the entire Rv2073 and Rv2074, and the COOH part of Mb2100c. In addition, while cobL exists as a single gene in Mycobacterium tuberculosis strain H37Rv, in Mycobacterium bovis a frameshift due to a single base insertion splits cobL into 2 parts, cobLa and cobLb; putative precorrin-6y methyltransferase 2293006 cobLa 11810361 cobLa Mycobacterium bovis BCG str. Mexico putative precorrin-6y methyltransferase YP_005171537.1 2292818 R 717522 CDS YP_005171538.1 378771805 11810362 complement(2293081..2293869) 1 NC_016804.1 In Mycobacterium bovis AF2122/97, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a large 2029 bp deletion(RD9) leads to the loss of the COOH part of Mb2100c, the entire Rv2074 and Rv2073, and the NH2 part of cobL compared to its homolog in Mycobacterium tuberculosis strain H37Rv; putative exported or envelope protein 2293869 11810362 BCGMEX_2077c Mycobacterium bovis BCG str. Mexico putative exported or envelope protein YP_005171538.1 2293081 R 717522 CDS YP_005171539.1 378771806 11810363 complement(2294027..2294278) 1 NC_016804.1 hypothetical protein 2294278 11810363 BCGMEX_2078c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171539.1 2294027 R 717522 CDS YP_005171540.1 378771807 11810364 complement(2294313..2295284) 1 NC_016804.1 putative transmembrane protein 2295284 11810364 BCGMEX_2079c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171540.1 2294313 R 717522 CDS YP_005171541.1 378771808 11810365 complement(2295285..2295584) 1 NC_016804.1 hypothetical protein 2295584 11810365 BCGMEX_2080c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171541.1 2295285 R 717522 CDS YP_005171542.1 378771809 11810366 2296049..2296363 1 NC_016804.1 Differs from Rv2078 by 1aa, G6E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2296363 11810366 BCGMEX_2081 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171542.1 2296049 D 717522 CDS YP_005171543.1 378771810 11810367 2296345..2298315 1 NC_016804.1 Differs from Rv2079 by 2aa, C47Y, L216P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2298315 11810367 BCGMEX_2082 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171543.1 2296345 D 717522 CDS YP_005171544.1 378771811 11810368 2298296..2298859 1 NC_016804.1 Differs from Rv2080 by 1aa, A23V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2298859 lppJ 11810368 lppJ Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171544.1 2298296 D 717522 CDS YP_005171545.1 378771812 11810369 complement(2298895..2299506) 1 NC_016804.1 putative transmembrane protein 2299506 11810369 BCGMEX_2084c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171545.1 2298895 R 717522 CDS YP_005171546.1 378771813 11810370 2299710..2301797 1 NC_016804.1 Differs from Mb2108 (721 aa) and from Rv2082 (721aa) by 26 codon in-frame deletion and from Rv2082 by 2aa, A183T, R612L in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 2301797 11810370 BCGMEX_2085 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171546.1 2299710 D 717522 CDS YP_005171547.1 378771814 11810371 2301794..2302738 1 NC_016804.1 Differs from Rv2083 by 1aa, V256L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2302738 11810371 BCGMEX_2086 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171547.1 2301794 D 717522 CDS YP_005171548.1 378771815 11810372 2302731..2303726 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2084 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to an 11bp insertion, splits Rv2084 into 2 parts; hypothetical protein 2303726 11810372 BCGMEX_2087 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171548.1 2302731 D 717522 CDS YP_005171549.1 378771816 11810374 2303961..2304266 1 NC_016804.1 hypothetical protein 2304266 11810374 BCGMEX_2089 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171549.1 2303961 D 717522 CDS YP_005171550.1 378771817 11810375 2304245..2304850 1 NC_016804.1 hypothetical protein 2304850 11810375 BCGMEX_2090 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171550.1 2304245 D 717522 CDS YP_005171551.1 378771818 11810376 2304928..2305158 1 NC_016804.1 hypothetical protein 2305158 11810376 BCGMEX_2091 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171551.1 2304928 D 717522 CDS YP_005171552.1 378771819 11810377 2305345..2307114 1 NC_016804.1 Transmembrane serine/threonine protein kinase J 2307114 pknJ 11810377 pknJ Mycobacterium bovis BCG str. Mexico Transmembrane serine/threonine protein kinase J YP_005171552.1 2305345 D 717522 CDS YP_005171553.1 378771820 11810378 complement(2307131..2308258) 1 NC_016804.1 putative Xaa-Pro dipeptidase 2308258 pepE 11810378 pepE Mycobacterium bovis BCG str. Mexico putative Xaa-Pro dipeptidase YP_005171553.1 2307131 R 717522 CDS YP_005171554.1 378771821 11810379 2308307..2309374 1 NC_016804.1 5'-3' exonuclease 2309374 11810379 BCGMEX_2094 Mycobacterium bovis BCG str. Mexico 5'-3' exonuclease YP_005171554.1 2308307 D 717522 CDS YP_005171555.1 378771822 11810380 complement(2309378..2310112) 1 NC_016804.1 hypothetical protein 2310112 11810380 BCGMEX_2095c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171555.1 2309378 R 717522 CDS YP_005171556.1 378771823 11810381 complement(2310154..2312874) 1 NC_016804.1 Differs from Rv2092c by 1aa, M178T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ATP-dependent DNA helicase 2312874 helY 11810381 helY Mycobacterium bovis BCG str. Mexico putative ATP-dependent DNA helicase YP_005171556.1 2310154 R 717522 CDS YP_005171557.1 378771824 11810382 complement(2312923..2313849) 1 NC_016804.1 Sec-independent protein translocase transmembrane protein 2313849 tatC 11810382 tatC Mycobacterium bovis BCG str. Mexico Sec-independent protein translocase transmembrane protein YP_005171557.1 2312923 R 717522 CDS YP_005171558.1 378771825 11810383 complement(2313866..2314117) 1 NC_016804.1 Sec-independent protein translocase protein tatA/E-like protein 2314117 tatA 11810383 tatA Mycobacterium bovis BCG str. Mexico Sec-independent protein translocase protein tatA/E-like protein YP_005171558.1 2313866 R 717522 CDS YP_005171559.1 378771826 11810384 complement(2314185..2315135) 1 NC_016804.1 Differs from Mb2122c by 1aa, A267V in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; proteasome accessory factor C 2315135 pafC 11810384 pafC Mycobacterium bovis BCG str. Mexico proteasome accessory factor C YP_005171559.1 2314185 R 717522 CDS YP_005171560.1 378771827 11810385 complement(2315132..2316130) 1 NC_016804.1 protein pafB 2316130 pafB 11810385 pafB Mycobacterium bovis BCG str. Mexico protein pafB YP_005171560.1 2315132 R 717522 CDS YP_005171561.1 378771828 11810386 complement(2316139..2317497) 1 NC_016804.1 pup--protein ligase 2317497 pafA 11810386 pafA Mycobacterium bovis BCG str. Mexico pup--protein ligase YP_005171561.1 2316139 R 717522 CDS YP_005171562.1 378771829 11810387 complement(2317549..2319024) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS36 and PE21 exist as 2 genes. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base insertion leads to a single product more similar to PE_PGRS36. There is also a 3 bp in-frame deletion; PE-PGRS family protein 2319024 PE_PGRS36 11810387 PE_PGRS36 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171562.1 2317549 R 717522 CDS YP_005171563.1 378771830 11810388 2319207..2320859 1 NC_016804.1 hypothetical protein 2320859 11810388 BCGMEX_2103 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171563.1 2319207 D 717522 CDS YP_005171564.1 378771831 11810389 2321058..2324099 1 NC_016804.1 Differs from Rv2101 by 3aa, L462M, Q601P, S652A in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative helicase 2324099 helZ 11810389 helZ Mycobacterium bovis BCG str. Mexico putative helicase YP_005171564.1 2321058 D 717522 CDS YP_005171565.1 378771832 11810390 2324209..2324925 1 NC_016804.1 hypothetical protein 2324925 11810390 BCGMEX_2105 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171565.1 2324209 D 717522 CDS YP_005171566.1 378771833 11810391 complement(2324904..2325338) 1 NC_016804.1 hypothetical protein 2325338 11810391 BCGMEX_2106c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171566.1 2324904 R 717522 CDS YP_005171567.1 378771834 11810392 complement(2325345..2325599) 1 NC_016804.1 hypothetical protein 2325599 11810392 BCGMEX_2107c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171567.1 2325345 R 717522 CDS YP_005171568.1 378771835 11810393 complement(2325615..2325872) 1 NC_016804.1 hypothetical protein 2325872 11810393 BCGMEX_2108c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171568.1 2325615 R 717522 CDS YP_005171569.1 378771836 11810394 2326819..2327115 1 NC_016804.1 PE family protein 2327115 PE22 11810394 PE22 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171569.1 2326819 D 717522 CDS YP_005171570.1 378771837 11810395 2327171..2327902 1 NC_016804.1 PPE family protein 2327902 PPE36 11810395 PPE36 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171570.1 2327171 D 717522 CDS YP_005171571.1 378771838 11810396 complement(2328442..2329188) 1 NC_016804.1 Differs from Rv2109c by 2aa, P135R, G182R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; proteasome subunit alpha 2329188 prcA 11810396 prcA Mycobacterium bovis BCG str. Mexico proteasome subunit alpha YP_005171571.1 2328442 R 717522 CDS YP_005171572.1 378771839 11810397 complement(2329185..2330060) 1 NC_016804.1 proteasome subunit beta 2330060 prcB 11810397 prcB Mycobacterium bovis BCG str. Mexico proteasome subunit beta YP_005171572.1 2329185 R 717522 CDS YP_005171573.1 378771840 11810398 complement(2330057..2330251) 1 NC_016804.1 ubiquitin-like protein Pup 2330251 11810398 BCGMEX_2113c Mycobacterium bovis BCG str. Mexico ubiquitin-like protein Pup YP_005171573.1 2330057 R 717522 CDS YP_005171574.1 378771841 11810399 complement(2330364..2331971) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 57 bp in-frame deletion at the NH2 part, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (535 aa versus 554 aa); hypothetical protein 2331971 11810399 BCGMEX_2114c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171574.1 2330364 R 717522 CDS YP_005171575.1 378771842 11810400 2332032..2333225 1 NC_016804.1 Differs from Mb2137 by 1aa, S278L, and from Rv2113 by 1aa, P207T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 2333225 11810400 BCGMEX_2115 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171575.1 2332032 D 717522 CDS YP_005171576.1 378771843 11810401 2333236..2333859 1 NC_016804.1 hypothetical protein 2333859 11810401 BCGMEX_2116 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171576.1 2333236 D 717522 CDS YP_005171577.1 378771844 11810402 complement(2333863..2335692) 1 NC_016804.1 proteasome-associated ATPase 2335692 11810402 BCGMEX_2117c Mycobacterium bovis BCG str. Mexico proteasome-associated ATPase YP_005171577.1 2333863 R 717522 CDS YP_005171578.1 378771845 11810403 2335973..2336542 1 NC_016804.1 putative lipoprotein 2336542 lppK 11810403 lppK Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171578.1 2335973 D 717522 CDS YP_005171579.1 378771846 11810404 2336550..2336843 1 NC_016804.1 hypothetical protein 2336843 11810404 BCGMEX_2119 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171579.1 2336550 D 717522 CDS YP_005171580.1 378771847 11810405 complement(2336872..2337714) 1 NC_016804.1 putative RNA methyltransferase 2337714 11810405 BCGMEX_2120c Mycobacterium bovis BCG str. Mexico putative RNA methyltransferase YP_005171580.1 2336872 R 717522 CDS YP_005171581.1 378771848 11810406 2337788..2338624 1 NC_016804.1 hypothetical protein 2338624 11810406 BCGMEX_2121 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171581.1 2337788 D 717522 CDS YP_005171582.1 378771849 11810407 complement(2338647..2339129) 1 NC_016804.1 putative integral membrane protein 2339129 11810407 BCGMEX_2122c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171582.1 2338647 R 717522 CDS YP_005171583.1 378771850 11810408 complement(2339208..2340062) 1 NC_016804.1 ATP phosphoribosyltransferase 2340062 hisG 11810408 hisG Mycobacterium bovis BCG str. Mexico ATP phosphoribosyltransferase YP_005171583.1 2339208 R 717522 CDS YP_005171584.1 378771851 11810409 complement(2340065..2340346) 1 NC_016804.1 phosphoribosyl-ATP pyrophosphatase 2340346 hisE 11810409 hisE Mycobacterium bovis BCG str. Mexico phosphoribosyl-ATP pyrophosphatase YP_005171584.1 2340065 R 717522 CDS YP_005171585.1 378771852 11810410 2340473..2341867 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 27 bp in-frame deletion leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (464 aa versus 473 aa); PPE family protein 2341867 PPE37 11810410 PPE37 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171585.1 2340473 D 717522 CDS YP_005171586.1 378771853 11810411 complement(2341864..2345442) 1 NC_016804.1 Differs from Rv2124c by 1aa, V752I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; methionine synthase, vitamin-B12 dependent isozyme, MS; 5-methyltetrahydrofolate--homocysteine methyltransferase 2345442 metH 11810411 metH Mycobacterium bovis BCG str. Mexico 5-methyltetrahydrofolate--homocysteine methyltransferase YP_005171586.1 2341864 R 717522 CDS YP_005171587.1 378771854 11810412 2345668..2346546 1 NC_016804.1 Differs from Rv2125 by 1aa, S33G in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2346546 11810412 BCGMEX_2127 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171587.1 2345668 D 717522 CDS YP_005171588.1 378771855 11810413 complement(2346577..2347347) 1 NC_016804.1 PE PGRS family protein 2347347 PE_PGRS37 11810413 PE_PGRS37 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005171588.1 2346577 R 717522 CDS YP_005171589.1 378771856 11810414 complement(2347344..2347610) 1 NC_016804.1 PE family protein 2347610 11810414 BCGMEX_2129c Mycobacterium bovis BCG str. Mexico PE family protein YP_005171589.1 2347344 R 717522 CDS YP_005171590.1 378771857 11810415 2347991..2349460 1 NC_016804.1 Differs from Rv2127 by 2aa, D9G, S44G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative L-asparagine permease 2349460 ansP1 11810415 ansP1 Mycobacterium bovis BCG str. Mexico putative L-asparagine permease YP_005171590.1 2347991 D 717522 CDS YP_005171591.1 378771858 11810416 2349460..2349663 1 NC_016804.1 putative transmembrane protein 2349663 11810416 BCGMEX_2131 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171591.1 2349460 D 717522 CDS YP_005171592.1 378771859 11810417 complement(2349683..2350564) 1 NC_016804.1 short-chain dehydrogenase 2350564 11810417 BCGMEX_2132c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005171592.1 2349683 R 717522 CDS YP_005171593.1 378771860 11810418 complement(2350590..2351834) 1 NC_016804.1 cysteinyl-tRNA synthetase 2351834 cysS2 11810418 cysS2 Mycobacterium bovis BCG str. Mexico cysteinyl-tRNA synthetase YP_005171593.1 2350590 R 717522 CDS YP_005171594.1 378771861 11810419 complement(2351892..2352695) 1 NC_016804.1 monophosphatase cysQ 2352695 cysQ 11810419 cysQ Mycobacterium bovis BCG str. Mexico monophosphatase cysQ YP_005171594.1 2351892 R 717522 CDS YP_005171595.1 378771862 11810420 2352786..2353016 1 NC_016804.1 DNA-binding protein, CopG family 2353016 11810420 BCGMEX_2135 Mycobacterium bovis BCG str. Mexico DNA-binding protein, CopG family YP_005171595.1 2352786 D 717522 CDS YP_005171596.1 378771863 11810421 complement(2353226..2354014) 1 NC_016804.1 hypothetical protein 2354014 11810421 BCGMEX_2136c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171596.1 2353226 R 717522 CDS YP_005171597.1 378771864 11810422 complement(2354025..2354612) 1 NC_016804.1 hypothetical protein 2354612 11810422 BCGMEX_2137c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171597.1 2354025 R 717522 CDS YP_005171598.1 378771865 11810423 complement(2354676..2355386) 1 NC_016804.1 hypothetical protein 2355386 11810423 BCGMEX_2138c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171598.1 2354676 R 717522 CDS YP_005171599.1 378771866 11810424 complement(2355383..2356213) 1 NC_016804.1 Differs from Mb2160c by 1aa L71V in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; undecaprenyl-diphosphatase 2356213 11810424 BCGMEX_2139c Mycobacterium bovis BCG str. Mexico undecaprenyl-diphosphatase YP_005171599.1 2355383 R 717522 CDS YP_005171600.1 378771867 11810425 complement(2356277..2356690) 1 NC_016804.1 hypothetical protein 2356690 11810425 BCGMEX_2140c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171600.1 2356277 R 717522 CDS YP_005171601.1 378771868 11810426 2356705..2357781 1 NC_016804.1 Differs from Mb2162 by 3aa, VQV348-350SRF, due to 7bp substitution in latter, in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2357781 lppL 11810426 lppL Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171601.1 2356705 D 717522 CDS YP_005171602.1 378771869 11810427 2358095..2359168 1 NC_016804.1 Differs from Rv2139 and Mb2163 by 1aa, C35R in BCG Pasteur, BCG Tokyo and BCG Mexico; dihydroorotate dehydrogenase 2359168 pyrD 11810427 pyrD Mycobacterium bovis BCG str. Mexico dihydroorotate dehydrogenase YP_005171602.1 2358095 D 717522 CDS YP_005171603.1 378771870 11810428 complement(2359173..2359703) 1 NC_016804.1 hypothetical protein 2359703 11810428 BCGMEX_2143c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171603.1 2359173 R 717522 CDS YP_005171604.1 378771871 11810429 complement(2359751..2361097) 1 NC_016804.1 hypothetical protein 2361097 11810429 BCGMEX_2144c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171604.1 2359751 R 717522 CDS YP_005171605.1 378771872 11810431 complement(2361568..2361885) 1 NC_016804.1 hypothetical protein 2361885 11810431 BCGMEX_2145c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171605.1 2361568 R 717522 CDS YP_005171606.1 378771873 11810432 complement(2361882..2362097) 1 NC_016804.1 hypothetical protein 2362097 11810432 BCGMEX_2146c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171606.1 2361882 R 717522 CDS YP_005171607.1 378771874 11810433 2362352..2363410 1 NC_016804.1 hypothetical protein 2363410 11810433 BCGMEX_2147 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171607.1 2362352 D 717522 CDS YP_005171608.1 378771875 11810434 complement(2363540..2363896) 1 NC_016804.1 putative transmembrane protein 2363896 11810434 BCGMEX_2148c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171608.1 2363540 R 717522 CDS YP_005171609.1 378771876 11810435 complement(2363991..2364773) 1 NC_016804.1 hypothetical protein 2364773 wag31 11810435 wag31 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171609.1 2363991 R 717522 CDS YP_005171610.1 378771877 11810436 complement(2365041..2365331) 1 NC_016804.1 putative transmembrane protein 2365331 11810436 BCGMEX_2150c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171610.1 2365041 R 717522 CDS YP_005171611.1 378771878 11810437 complement(2365493..2366218) 1 NC_016804.1 hypothetical protein 2366218 11810437 BCGMEX_2151c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171611.1 2365493 R 717522 CDS YP_005171612.1 378771879 11810438 complement(2366215..2366991) 1 NC_016804.1 hypothetical protein 2366991 11810438 BCGMEX_2152c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171612.1 2366215 R 717522 CDS YP_005171613.1 378771880 11810439 complement(2366997..2367749) 1 NC_016804.1 hypothetical protein 2367749 yfiH 11810439 yfiH Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171613.1 2366997 R 717522 CDS YP_005171614.1 378771881 11810440 complement(2367760..2368899) 1 NC_016804.1 cell division protein ftsZ 2368899 ftsZ 11810440 ftsZ Mycobacterium bovis BCG str. Mexico cell division protein ftsZ YP_005171614.1 2367760 R 717522 CDS YP_005171615.1 378771882 11810441 complement(2369072..2370016) 1 NC_016804.1 cell division protein ftsQ 2370016 ftsQ 11810441 ftsQ Mycobacterium bovis BCG str. Mexico cell division protein ftsQ YP_005171615.1 2369072 R 717522 CDS YP_005171616.1 378771883 11810442 complement(2370013..2371497) 1 NC_016804.1 UDP-N-acetylmuramate--L-alanine ligase 2371497 murC 11810442 murC Mycobacterium bovis BCG str. Mexico UDP-N-acetylmuramate--L-alanine ligase YP_005171616.1 2370013 R 717522 CDS YP_005171617.1 378771884 11810443 complement(2371494..2372726) 1 NC_016804.1 Differs from Rv2153c by 2aa, L36V, P74L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase 2372726 murG 11810443 murG Mycobacterium bovis BCG str. Mexico UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase YP_005171617.1 2371494 R 717522 CDS YP_005171618.1 378771885 11810444 complement(2372723..2374297) 1 NC_016804.1 cell division protein FtsW 2374297 ftsW 11810444 ftsW Mycobacterium bovis BCG str. Mexico cell division protein FtsW YP_005171618.1 2372723 R 717522 CDS YP_005171619.1 378771886 11810445 complement(2374309..2375769) 1 NC_016804.1 Differs from Rv2155c by 1aa, G247R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; UDP-N-acetylmuramoylalanine--D-glutamate ligase 2375769 murD 11810445 murD Mycobacterium bovis BCG str. Mexico UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_005171619.1 2374309 R 717522 CDS YP_005171620.1 378771887 11810446 complement(2375771..2376850) 1 NC_016804.1 phospho-N-acetylmuramoyl-pentappeptide transferase 2376850 mraY 11810446 mraY Mycobacterium bovis BCG str. Mexico phospho-N-acetylmuramoyl-pentappeptide transferase YP_005171620.1 2375771 R 717522 CDS YP_005171621.1 378771888 11810447 complement(2376847..2378379) 1 NC_016804.1 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D- alanyl ligase 2378379 murF 11810447 murF Mycobacterium bovis BCG str. Mexico UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D- alanyl ligase YP_005171621.1 2376847 R 717522 CDS YP_005171622.1 378771889 11810448 complement(2378376..2379983) 1 NC_016804.1 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 2379983 murE 11810448 murE Mycobacterium bovis BCG str. Mexico UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_005171622.1 2378376 R 717522 CDS YP_005171623.1 378771890 11810449 complement(2380006..2381040) 1 NC_016804.1 hypothetical protein 2381040 11810449 BCGMEX_2163c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171623.1 2380006 R 717522 CDS YP_005171624.1 378771891 11810450 complement(2381037..2381657) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2160A and Rv2160c exist as 2 genes with an overlap region between them. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and bCG Mexico, a 4 bp insertion leads to a single product; hypothetical protein 2381657 11810450 BCGMEX_2164c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171624.1 2381037 R 717522 CDS YP_005171625.1 378771892 11810451 complement(2381650..2382516) 1 NC_016804.1 hypothetical protein 2382516 11810451 BCGMEX_2165c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171625.1 2381650 R 717522 CDS YP_005171626.1 378771893 11810452 complement(2382619..2384091) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, in-frame deletions of 108 bp and 18 bp leads to a shorter product than in Mycobacterium tuberculosis strain H37Rv (490 aa versus 532 aa); PE-PGRS family protein 2384091 PE_PGRS38 11810452 PE_PGRS38 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171626.1 2382619 R 717522 CDS YP_005171627.1 378771894 11810453 complement(2384301..2386340) 1 NC_016804.1 putative penicillin-binding membrane protein 2386340 pbpB 11810453 pbpB Mycobacterium bovis BCG str. Mexico putative penicillin-binding membrane protein YP_005171627.1 2384301 R 717522 CDS YP_005171628.1 378771895 11810454 complement(2386337..2387491) 1 NC_016804.1 Differs from Mb2188c by 1aa, V202A in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2387491 11810454 BCGMEX_2168c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171628.1 2386337 R 717522 CDS YP_005171629.1 378771896 11810455 complement(2387488..2388678) 1 NC_016804.1 S-adenosyl-methyltransferase 2388678 mraW 11810455 mraW Mycobacterium bovis BCG str. Mexico S-adenosyl-methyltransferase YP_005171629.1 2387488 R 717522 CDS YP_005171630.1 378771897 11810456 complement(2388680..2389111) 1 NC_016804.1 cell division protein MraZ 2389111 mraZ 11810456 mraZ Mycobacterium bovis BCG str. Mexico cell division protein MraZ YP_005171630.1 2388680 R 717522 CDS YP_005171631.1 378771898 11810457 complement(2389460..2389864) 1 NC_016804.1 transmembrane protein 2389864 11810457 BCGMEX_2171c Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005171631.1 2389460 R 717522 CDS YP_005171632.1 378771899 11810458 2390130..2390750 1 NC_016804.1 hypothetical protein 2390750 11810458 BCGMEX_2172 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171632.1 2390130 D 717522 CDS YP_005171633.1 378771900 11810459 2390846..2391529 1 NC_016804.1 putative lipoprotein 2391529 lppM 11810459 lppM Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171633.1 2390846 D 717522 CDS YP_005171634.1 378771901 11810460 complement(2391526..2392431) 1 NC_016804.1 hypothetical protein 2392431 11810460 BCGMEX_2174c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171634.1 2391526 R 717522 CDS YP_005171635.1 378771902 11810461 2392742..2393800 1 NC_016804.1 putative geranylgeranyl pyrophosphate synthetase 2393800 idsA2 11810461 idsA2 Mycobacterium bovis BCG str. Mexico putative geranylgeranyl pyrophosphate synthetase YP_005171635.1 2392742 D 717522 CDS YP_005171636.1 378771903 11810462 2393804..2395507 1 NC_016804.1 Differs from Rv2174 and Mb2196 at 3'-end owing to frameshift due to 1 bp insertion, and from Rv2174 by 1aa, S451A in BCG Pasteur, BCG Tokyo and BCG Mexico; integral membrane protein 2395507 11810462 BCGMEX_2176 Mycobacterium bovis BCG str. Mexico integral membrane protein YP_005171636.1 2393804 D 717522 CDS YP_005171637.1 378771904 11810463 complement(2395342..2395782) 1 NC_016804.1 Differs from Rv2175c by 1aa, L17P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative regulatory protein 2395782 11810463 BCGMEX_2177c Mycobacterium bovis BCG str. Mexico putative regulatory protein YP_005171637.1 2395342 R 717522 CDS YP_005171638.1 378771905 11810464 2395837..2397036 1 NC_016804.1 Differs from Rv2176 by 1aa, A52S in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative serine/threonine protein kinase L 2397036 pknL 11810464 pknL Mycobacterium bovis BCG str. Mexico putative serine/threonine protein kinase L YP_005171638.1 2395837 D 717522 CDS YP_005171639.1 378771906 11810465 complement(2397178..2397843) 1 NC_016804.1 Differs from Rv2177c by 1aa, K115T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 2397843 11810465 BCGMEX_2179c Mycobacterium bovis BCG str. Mexico putative transposase YP_005171639.1 2397178 R 717522 CDS YP_005171640.1 378771907 11810466 complement(2398228..2399616) 1 NC_016804.1 Differs from Rv2178c by 1aa, E265D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative 3-deoxy-D-arabino-heptulosonate-7- phosphate synthase II 2399616 aroG 11810466 aroG Mycobacterium bovis BCG str. Mexico putative 3-deoxy-D-arabino-heptulosonate-7- phosphate synthase II YP_005171640.1 2398228 R 717522 CDS YP_005171641.1 378771908 11810467 complement(2399707..2400213) 1 NC_016804.1 hypothetical protein 2400213 11810467 BCGMEX_2181c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171641.1 2399707 R 717522 CDS YP_005171642.1 378771909 11810468 complement(2400223..2401110) 1 NC_016804.1 Differs from Rv2180c by 1aa, T156P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 2401110 11810468 BCGMEX_2182c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171642.1 2400223 R 717522 CDS YP_005171643.1 378771910 11810469 2401198..2402481 1 NC_016804.1 putative integral membrane protein 2402481 11810469 BCGMEX_2183 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171643.1 2401198 D 717522 CDS YP_005171644.1 378771911 11810470 complement(2402482..2403225) 1 NC_016804.1 1-acylglycerol-3-phosphate O-acyltransferase 2403225 11810470 BCGMEX_2184c Mycobacterium bovis BCG str. Mexico 1-acylglycerol-3-phosphate O-acyltransferase YP_005171644.1 2402482 R 717522 CDS YP_005171645.1 378771912 11810471 complement(2403311..2403706) 1 NC_016804.1 hypothetical protein 2403706 11810471 BCGMEX_2185c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171645.1 2403311 R 717522 CDS YP_005171646.1 378771913 11810472 complement(2403703..2404842) 1 NC_016804.1 hypothetical protein 2404842 11810472 BCGMEX_2186c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171646.1 2403703 R 717522 CDS YP_005171647.1 378771914 11810473 complement(2404962..2405396) 1 NC_016804.1 hypothetical protein 2405396 11810473 BCGMEX_2187c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171647.1 2404962 R 717522 CDS YP_005171648.1 378771915 11810474 complement(2405501..2405890) 1 NC_016804.1 hypothetical protein 2405890 11810474 BCGMEX_2188c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171648.1 2405501 R 717522 CDS YP_005171649.1 378771916 11810475 2406056..2406568 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, fadD15 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to single base deletion splits fadD15 into 2 parts.; hypothetical protein 2406568 11810475 BCGMEX_2189 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171649.1 2406056 D 717522 CDS YP_005171650.1 378771917 11810476 2406331..2407857 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, fadD15 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to single base deletion splits fadD15 into 2 parts. Differs from Rv2187 by 2aa, I8T, E287G in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative long-chain-fatty-acid--CoA ligase 2407857 fadD15 11810476 fadD15 Mycobacterium bovis BCG str. Mexico putative long-chain-fatty-acid--CoA ligase YP_005171650.1 2406331 D 717522 CDS YP_005171651.1 378771918 11810477 complement(2407888..2409045) 1 NC_016804.1 glycosyltransferase 2409045 11810477 BCGMEX_2191c Mycobacterium bovis BCG str. Mexico glycosyltransferase YP_005171651.1 2407888 R 717522 CDS YP_005171652.1 378771919 11810478 complement(2409142..2409915) 1 NC_016804.1 hypothetical protein 2409915 11810478 BCGMEX_2192c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171652.1 2409142 R 717522 CDS YP_005171653.1 378771920 11810479 complement(2410010..2411167) 1 NC_016804.1 hypothetical protein 2411167 11810479 BCGMEX_2193c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171653.1 2410010 R 717522 CDS YP_005171654.1 378771921 11810480 2411714..2413651 1 NC_016804.1 Differs from Rv2191 by 1aa, T272A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2413651 11810480 BCGMEX_2194 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171654.1 2411714 D 717522 CDS YP_005171655.1 378771922 11810481 complement(2413526..2414638) 1 NC_016804.1 anthranilate phosphoribosyltransferase 2414638 trpD 11810481 trpD Mycobacterium bovis BCG str. Mexico anthranilate phosphoribosyltransferase YP_005171655.1 2413526 R 717522 CDS YP_005171656.1 378771923 11810482 2414796..2415407 1 NC_016804.1 putative cytochrome c oxidase subunit III 2415407 ctaE 11810482 ctaE Mycobacterium bovis BCG str. Mexico putative cytochrome c oxidase subunit III YP_005171656.1 2414796 D 717522 CDS YP_005171657.1 378771924 11810483 2415448..2416290 1 NC_016804.1 putative ubiquinol cytochrome C reductase, cytochrome C1 subunit 2416290 qcrC 11810483 qcrC Mycobacterium bovis BCG str. Mexico putative ubiquinol cytochrome C reductase, cytochrome C1 subunit YP_005171657.1 2415448 D 717522 CDS YP_005171658.1 378771925 11810484 2416287..2417576 1 NC_016804.1 Differs from Rv2195 by 1aa, I281M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Ubiquinol-cytochrome C reductase iron-sulfur subunit 2417576 qcrA 11810484 qcrA Mycobacterium bovis BCG str. Mexico Ubiquinol-cytochrome C reductase iron-sulfur subunit YP_005171658.1 2416287 D 717522 CDS YP_005171659.1 378771926 11810485 2417573..2419222 1 NC_016804.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit 2419222 qcrB 11810485 qcrB Mycobacterium bovis BCG str. Mexico Ubiquinol--cytochrome c reductase, cytochrome B subunit YP_005171659.1 2417573 D 717522 CDS YP_005171660.1 378771927 11810486 complement(2419513..2420157) 1 NC_016804.1 Differs from Rv2197c by 1aa, S202A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 2420157 11810486 BCGMEX_2200c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171660.1 2419513 R 717522 CDS YP_005171661.1 378771928 11810487 complement(2420157..2421056) 1 NC_016804.1 hypothetical protein 2421056 mmpS3 11810487 mmpS3 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171661.1 2420157 R 717522 CDS YP_005171662.1 378771929 11810488 complement(2421242..2421661) 1 NC_016804.1 putative cytochrome c oxidase polypeptide 4 2421661 ctaF 11810488 ctaF Mycobacterium bovis BCG str. Mexico putative cytochrome c oxidase polypeptide 4 YP_005171662.1 2421242 R 717522 CDS YP_005171663.1 378771930 11810489 complement(2421669..2422760) 1 NC_016804.1 putative cytochrome c oxidase subunit II 2422760 ctaC 11810489 ctaC Mycobacterium bovis BCG str. Mexico putative cytochrome c oxidase subunit II YP_005171663.1 2421669 R 717522 CDS YP_005171664.1 378771931 11810490 2423006..2424964 1 NC_016804.1 putative asparagine synthetase 2424964 asnB 11810490 asnB Mycobacterium bovis BCG str. Mexico putative asparagine synthetase YP_005171664.1 2423006 D 717522 CDS YP_005171665.1 378771932 11810491 complement(2425062..2426036) 1 NC_016804.1 adenosine kinase 2426036 adoK 11810491 adoK Mycobacterium bovis BCG str. Mexico adenosine kinase YP_005171665.1 2425062 R 717522 CDS YP_005171666.1 378771933 11810492 2426240..2426932 1 NC_016804.1 hypothetical protein 2426932 11810492 BCGMEX_2206 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171666.1 2426240 D 717522 CDS YP_005171667.1 378771934 11810493 complement(2426940..2427296) 1 NC_016804.1 hypothetical protein 2427296 11810493 BCGMEX_2207c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171667.1 2426940 R 717522 CDS YP_005171668.1 378771935 11810494 complement(2427396..2428472) 1 NC_016804.1 hypothetical protein 2428472 11810494 BCGMEX_2208c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171668.1 2427396 R 717522 CDS YP_005171669.1 378771936 11810495 2428631..2429341 1 NC_016804.1 putative transmembrane protein 2429341 11810495 BCGMEX_2209 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171669.1 2428631 D 717522 CDS YP_005171670.1 378771937 11810496 2429420..2430505 1 NC_016804.1 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2430505 cobT 11810496 cobT Mycobacterium bovis BCG str. Mexico nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_005171670.1 2429420 D 717522 CDS YP_005171671.1 378771938 11810497 2430502..2431251 1 NC_016804.1 Differs from Rv2208 by 1aa, S155L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; cobalamin synthase 2431251 cobS 11810497 cobS Mycobacterium bovis BCG str. Mexico cobalamin synthase YP_005171671.1 2430502 D 717522 CDS YP_005171672.1 378771939 11810498 2431409..2432947 1 NC_016804.1 putative integral membrane protein 2432947 11810498 BCGMEX_2212 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171672.1 2431409 D 717522 CDS YP_005171673.1 378771940 11810499 complement(2432873..2433979) 1 NC_016804.1 Differs from Rv2210c by 1aa, A28E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; branched-chain amino acid aminotransferase 2433979 ilvE 11810499 ilvE Mycobacterium bovis BCG str. Mexico branched-chain amino acid aminotransferase YP_005171673.1 2432873 R 717522 CDS YP_005171674.1 378771941 11810500 complement(2434051..2435190) 1 NC_016804.1 aminomethyltransferase (glycine cleavage system T protein) 2435190 gcvT 11810500 gcvT Mycobacterium bovis BCG str. Mexico aminomethyltransferase (glycine cleavage system T protein) YP_005171674.1 2434051 R 717522 CDS YP_005171675.1 378771942 11810501 2435199..2436335 1 NC_016804.1 hypothetical protein 2436335 11810501 BCGMEX_2215 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171675.1 2435199 D 717522 CDS YP_005171676.1 378771943 11810502 2436347..2437894 1 NC_016804.1 Differs from Rv2213 by 1aa, L210F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytosol aminopeptidase 2437894 pepB 11810502 pepB Mycobacterium bovis BCG str. Mexico putative cytosol aminopeptidase YP_005171676.1 2436347 D 717522 CDS YP_005171677.1 378771944 11810503 complement(2437932..2439710) 1 NC_016804.1 short-chain dehydrogenase 2439710 ephD 11810503 ephD Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005171677.1 2437932 R 717522 CDS YP_005171678.1 378771945 11810504 2439974..2441635 1 NC_016804.1 Differs from Rv2215 and Mb2238 by 1aa, V517L in BCG Pasteur, BCG Tokyo and BCG Mexico; dihydrolipoamide acyltransferase 2441635 dlaT 11810504 dlaT Mycobacterium bovis BCG str. Mexico dihydrolipoamide acyltransferase YP_005171678.1 2439974 D 717522 CDS YP_005171679.1 378771946 11810505 2441635..2442540 1 NC_016804.1 hypothetical protein 2442540 11810505 BCGMEX_2219 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171679.1 2441635 D 717522 CDS YP_005171680.1 378771947 11810506 2442593..2443285 1 NC_016804.1 Differs from Rv2217 by 1aa, G73D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Octanoyltransferase 2443285 lipB 11810506 lipB Mycobacterium bovis BCG str. Mexico Octanoyltransferase YP_005171680.1 2442593 D 717522 CDS YP_005171681.1 378771948 11810507 2443282..2444217 1 NC_016804.1 lipoyl synthase 2444217 lipA 11810507 lipA Mycobacterium bovis BCG str. Mexico lipoyl synthase YP_005171681.1 2443282 D 717522 CDS YP_005171682.1 378771949 11810508 2444244..2444996 1 NC_016804.1 Differs from Rv2219 by 1aa, L74F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 2444996 11810508 BCGMEX_2222 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171682.1 2444244 D 717522 CDS YP_005171683.1 378771950 11810509 complement(2445003..2445425) 1 NC_016804.1 hypothetical protein 2445425 11810509 BCGMEX_2223c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171683.1 2445003 R 717522 CDS YP_005171684.1 378771951 11810510 2445624..2447060 1 NC_016804.1 glutamine synthetase 2447060 glnA1 11810510 glnA1 Mycobacterium bovis BCG str. Mexico glutamine synthetase YP_005171684.1 2445624 D 717522 CDS YP_005171685.1 378771952 11810511 complement(2447378..2450362) 1 NC_016804.1 glutamate-ammonia-ligase adenylyltransferase 2450362 glnE 11810511 glnE Mycobacterium bovis BCG str. Mexico glutamate-ammonia-ligase adenylyltransferase YP_005171685.1 2447378 R 717522 CDS YP_005171686.1 378771953 11810512 complement(2450411..2451751) 1 NC_016804.1 putative glutamine synthetase 2451751 glnA2 11810512 glnA2 Mycobacterium bovis BCG str. Mexico putative glutamine synthetase YP_005171686.1 2450411 R 717522 CDS YP_005171687.1 378771954 11810513 complement(2451846..2453408) 1 NC_016804.1 Differs from Rv2223c and Mb2247c by 1aa, S307A in BCG Pasteur and BCG Tokyo; putative exported protease 2453408 11810513 BCGMEX_2227c Mycobacterium bovis BCG str. Mexico putative exported protease YP_005171687.1 2451846 R 717522 CDS YP_005171688.1 378771955 11810514 complement(2453470..2455032) 1 NC_016804.1 putative exported protease 2455032 11810514 BCGMEX_2228c Mycobacterium bovis BCG str. Mexico putative exported protease YP_005171688.1 2453470 R 717522 CDS YP_005171689.1 378771956 11810515 complement(2455234..2455425) 1 NC_016804.1 hypothetical protein 2455425 11810515 BCGMEX_2229c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171689.1 2455234 R 717522 CDS YP_005171690.1 378771957 11810516 2455751..2456596 1 NC_016804.1 3-methyl-2-oxobutanoate hydroxymethyltransferase 2456596 panB 11810516 panB Mycobacterium bovis BCG str. Mexico 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_005171690.1 2455751 D 717522 CDS YP_005171691.1 378771958 11810517 2456841..2458382 1 NC_016804.1 Differs from Rv2226 and Mb2250 by 1aa, N299D andG31D, respectively, in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2458382 11810517 BCGMEX_2231 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171691.1 2456841 D 717522 CDS YP_005171692.1 378771959 11810519 2458940..2459260 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2227 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 1bp to 2bp substitution splits Rv2227 in two parts; hypothetical protein 2459260 11810519 BCGMEX_2232 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171692.1 2458940 D 717522 CDS YP_005171693.1 378771960 11810520 2459268..2459642 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2227 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 1bp to 2bp substitution splits Rv2227 in two parts; hypothetical protein 2459642 11810520 BCGMEX_2233 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171693.1 2459268 D 717522 CDS YP_005171694.1 378771961 11810521 complement(2459654..2460748) 1 NC_016804.1 hypothetical protein 2460748 11810521 BCGMEX_2234c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171694.1 2459654 R 717522 CDS YP_005171695.1 378771962 11810522 complement(2460745..2461482) 1 NC_016804.1 Differs from Rv2229c by 1aa, Q239R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2461482 11810522 BCGMEX_2235c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171695.1 2460745 R 717522 CDS YP_005171696.1 378771963 11810523 complement(2461479..2462618) 1 NC_016804.1 hypothetical protein 2462618 11810523 BCGMEX_2236c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171696.1 2461479 R 717522 CDS YP_005171697.1 378771964 11810524 complement(2462615..2463709) 1 NC_016804.1 putative aminotransferase 2463709 cobC 11810524 cobC Mycobacterium bovis BCG str. Mexico putative aminotransferase YP_005171697.1 2462615 R 717522 CDS YP_005171698.1 378771965 11810525 2464288..2465163 1 NC_016804.1 hypothetical protein 2465163 11810525 BCGMEX_2238 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171698.1 2464288 D 717522 CDS YP_005171699.1 378771966 11810526 2465156..2465647 1 NC_016804.1 phosphotyrosine protein phosphatase 2465647 ptpA 11810526 ptpA Mycobacterium bovis BCG str. Mexico phosphotyrosine protein phosphatase YP_005171699.1 2465156 D 717522 CDS YP_005171700.1 378771967 11810527 2465647..2466462 1 NC_016804.1 putative transmembrane protein 2466462 11810527 BCGMEX_2240 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171700.1 2465647 D 717522 CDS YP_005171701.1 378771968 11810528 complement(2466444..2467385) 1 NC_016804.1 Differs from Rv2236c by 2aa, I5T, C79S in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; Cobalamin biosynthesis protein 2467385 cobD 11810528 cobD Mycobacterium bovis BCG str. Mexico Cobalamin biosynthesis protein YP_005171701.1 2466444 R 717522 CDS YP_005171702.1 378771969 11810529 2467499..2468266 1 NC_016804.1 hypothetical protein 2468266 11810529 BCGMEX_2242 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171702.1 2467499 D 717522 CDS YP_005171703.1 378771970 11810531 complement(2468725..2469186) 1 NC_016804.1 peroxiredoxin 2469186 ahpE 11810531 ahpE Mycobacterium bovis BCG str. Mexico peroxiredoxin YP_005171703.1 2468725 R 717522 CDS YP_005171704.1 378771971 11810532 complement(2469186..2469662) 1 NC_016804.1 hypothetical protein 2469662 11810532 BCGMEX_2244c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171704.1 2469186 R 717522 CDS YP_005171705.1 378771972 11810533 complement(2469700..2470497) 1 NC_016804.1 Differs from Rv2240c by 1aa, K259T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2470497 11810533 BCGMEX_2245c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171705.1 2469700 R 717522 CDS YP_005171706.1 378771973 11810534 2470549..2473254 1 NC_016804.1 Differs from Mb2265 by 1aa, G309R in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokio and BCG Mexico; Pyruvate dehydrogenase subunit E1 2473254 aceE 11810534 aceE Mycobacterium bovis BCG str. Mexico Pyruvate dehydrogenase subunit E1 YP_005171706.1 2470549 D 717522 CDS YP_005171707.1 378771974 11810535 2473314..2474558 1 NC_016804.1 Differs from Rv2242 and Mb2266 by 1aa, T363A in BCG Pasteur, BCG Tokyo and Mexico; hypothetical protein 2474558 11810535 BCGMEX_2247 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171707.1 2473314 D 717522 CDS YP_005171708.1 378771975 11810536 2474797..2475705 1 NC_016804.1 Malonyl CoA-acyl carrier protein transacylase 2475705 fabD 11810536 fabD Mycobacterium bovis BCG str. Mexico Malonyl CoA-acyl carrier protein transacylase YP_005171708.1 2474797 D 717522 CDS YP_005171709.1 378771976 11810537 2475781..2476128 1 NC_016804.1 acyl carrier protein 2476128 acpP 11810537 acpP Mycobacterium bovis BCG str. Mexico acyl carrier protein YP_005171709.1 2475781 D 717522 CDS YP_005171710.1 378771977 11810538 2476125..2477375 1 NC_016804.1 3-oxoacyl-ACP synthase 2477375 kasA 11810538 kasA Mycobacterium bovis BCG str. Mexico 3-oxoacyl-ACP synthase YP_005171710.1 2476125 D 717522 CDS YP_005171711.1 378771978 11810539 2477406..2478722 1 NC_016804.1 3-oxoacyl-ACP synthase 2478722 kasB 11810539 kasB Mycobacterium bovis BCG str. Mexico 3-oxoacyl-ACP synthase YP_005171711.1 2477406 D 717522 CDS YP_005171712.1 378771979 11810540 2478753..2480174 1 NC_016804.1 acetyl/propionyl-CoA carboxylase subunit beta 2480174 accD6 11810540 accD6 Mycobacterium bovis BCG str. Mexico acetyl/propionyl-CoA carboxylase subunit beta YP_005171712.1 2478753 D 717522 CDS YP_005171713.1 378771980 11810541 2480282..2480686 1 NC_016804.1 In Mycobacterium bovis and Mycobacterium tuberculosis, Rv2248 and Mb2272 exist as single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, the ortholog is split into two parts owing to single base insertion in G-string; hypothetical protein 2480686 11810541 BCGMEX_2253 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171713.1 2480282 D 717522 CDS YP_005171714.1 378771981 11810542 2480394..2481098 1 NC_016804.1 In Mycobacterium bovis and Mycobacterium tuberculosis, Rv2248 and Mb2272 exist as single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, the ortholog is split into two parts owing to single base insertion in G-string; hypothetical protein 2481098 11810542 BCGMEX_2254 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171714.1 2480394 D 717522 CDS YP_005171715.1 378771982 11810543 complement(2481167..2482717) 1 NC_016804.1 glycerol-3-phosphate dehydrogenase 2482717 glpD1 11810543 glpD1 Mycobacterium bovis BCG str. Mexico glycerol-3-phosphate dehydrogenase YP_005171715.1 2481167 R 717522 CDS YP_005171716.1 378771983 11810544 complement(2482711..2483280) 1 NC_016804.1 Differs from Mb2274c by 1aa, D68A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 2483280 11810544 BCGMEX_2256c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005171716.1 2482711 R 717522 CDS YP_005171717.1 378771984 11810545 2483328..2484917 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, Rv2250A and Rv2251 exist as 2 genes with an overlap region between them. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base deletion leads to a single product; putative alkyl-dihydroxyacetonephosphate synthase 2484917 11810545 BCGMEX_2257 Mycobacterium bovis BCG str. Mexico putative alkyl-dihydroxyacetonephosphate synthase YP_005171717.1 2483328 D 717522 CDS YP_005171718.1 378771985 11810546 2484914..2485843 1 NC_016804.1 diacylglycerol kinase 2485843 11810546 BCGMEX_2258 Mycobacterium bovis BCG str. Mexico diacylglycerol kinase YP_005171718.1 2484914 D 717522 CDS YP_005171719.1 378771986 11810547 2485909..2486412 1 NC_016804.1 Possible secreted unknown protein; hypothetical protein 2486412 11810547 BCGMEX_2259 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171719.1 2485909 D 717522 CDS YP_005171720.1 378771987 11810548 complement(2486445..2486900) 1 NC_016804.1 Differs from Rv2254c by 1aa, V68A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 2486900 11810548 BCGMEX_2260c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171720.1 2486445 R 717522 CDS YP_005171721.1 378771988 11810549 complement(2486905..2487099) 1 NC_016804.1 hypothetical protein 2487099 11810549 BCGMEX_2261c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171721.1 2486905 R 717522 CDS YP_005171722.1 378771989 11810550 complement(2487266..2487799) 1 NC_016804.1 Differs from Rv2256c by 1aa, G26A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2487799 11810550 BCGMEX_2262c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171722.1 2487266 R 717522 CDS YP_005171723.1 378771990 11810551 complement(2487929..2488747) 1 NC_016804.1 hypothetical protein 2488747 11810551 BCGMEX_2263c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171723.1 2487929 R 717522 CDS YP_005171724.1 378771991 11810552 complement(2488761..2489822) 1 NC_016804.1 putative transcriptional regulatory protein 2489822 11810552 BCGMEX_2264c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005171724.1 2488761 R 717522 CDS YP_005171725.1 378771992 11810553 2490064..2491149 1 NC_016804.1 putative zinc-dependent alcohol dehydrogenase 2491149 adhE2 11810553 adhE2 Mycobacterium bovis BCG str. Mexico putative zinc-dependent alcohol dehydrogenase YP_005171725.1 2490064 D 717522 CDS YP_005171726.1 378771993 11810554 2491149..2491784 1 NC_016804.1 hypothetical protein 2491784 11810554 BCGMEX_2266 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171726.1 2491149 D 717522 CDS YP_005171727.1 378771994 11810555 complement(2491861..2493369) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2262cand Rv2261c exist as 2 genes. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 2 bp deletion results in a single product; hypothetical protein 2493369 11810555 BCGMEX_2267c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171727.1 2491861 R 717522 CDS YP_005171728.1 378771995 11810556 2493458..2494411 1 NC_016804.1 short-chain dehydrogenase 2494411 11810556 BCGMEX_2268 Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005171728.1 2493458 D 717522 CDS YP_005171729.1 378771996 11810557 complement(2494389..2496167) 1 NC_016804.1 hypothetical protein 2496167 11810557 BCGMEX_2269c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171729.1 2494389 R 717522 CDS YP_005171730.1 378771997 11810558 2496517..2497746 1 NC_016804.1 putative transmembrane protein 2497746 11810558 BCGMEX_2270 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171730.1 2496517 D 717522 CDS YP_005171731.1 378771998 11810559 2497921..2499207 1 NC_016804.1 putative cytochrome P450 hydroxylase 2499207 cyp124 11810559 cyp124 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 hydroxylase YP_005171731.1 2497921 D 717522 CDS YP_005171732.1 378771999 11810560 complement(2499461..2500627) 1 NC_016804.1 hypothetical protein 2500627 11810560 BCGMEX_2272c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171732.1 2499461 R 717522 CDS YP_005171733.1 378772000 11810561 complement(2500624..2502093) 1 NC_016804.1 Differs from Rv2268c and Mb2291c by 1aa, F203L in BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytochrome P450 128 2502093 cyp128 11810561 cyp128 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 128 YP_005171733.1 2500624 R 717522 CDS YP_005171734.1 378772001 11810562 complement(2502106..2502438) 1 NC_016804.1 hypothetical protein 2502438 11810562 BCGMEX_2274c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171734.1 2502106 R 717522 CDS YP_005171735.1 378772002 11810563 2502515..2503042 1 NC_016804.1 Differs from Mb2293 by 1aa, P152L in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2503042 lppN 11810563 lppN Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171735.1 2502515 D 717522 CDS YP_005171736.1 378772003 11810564 2503149..2503448 1 NC_016804.1 hypothetical protein 2503448 11810564 BCGMEX_2276 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171736.1 2503149 D 717522 CDS YP_005171737.1 378772004 11810565 2503554..2503922 1 NC_016804.1 hypothetical protein 2503922 11810565 BCGMEX_2277 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171737.1 2503554 D 717522 CDS YP_005171738.1 378772005 11810566 2503919..2504248 1 NC_016804.1 putative transmembrane protein 2504248 11810566 BCGMEX_2278 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171738.1 2503919 D 717522 CDS YP_005171739.1 378772006 11810567 complement(2504305..2504622) 1 NC_016804.1 Differs from Rv2274c by 1aa, M33I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2504622 11810567 BCGMEX_2279c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171739.1 2504305 R 717522 CDS YP_005171740.1 378772007 11810568 2504700..2505569 1 NC_016804.1 Differs from Rv2275 and Mb2298 by 1aa, A261E in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2505569 11810568 BCGMEX_2280 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171740.1 2504700 D 717522 CDS YP_005171741.1 378772008 11810569 2505566..2506756 1 NC_016804.1 cytochrome P450 hydroxylase 2506756 cyp121 11810569 cyp121 Mycobacterium bovis BCG str. Mexico cytochrome P450 hydroxylase YP_005171741.1 2505566 D 717522 CDS YP_005171742.1 378772009 11810570 complement(2506941..2507840) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 1358 bp deletion containing an IS6110 sequence, disrupts the 5' start of Rv2277c resulting in a slightly shorter product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (299 aa versus 301 aa). Differs from Mb2300c by 1aa in BCG Pasteur, BCG Tokyo and BCG Mexico; putative glycerolphosphodiesterase 2507840 11810570 BCGMEX_2282c Mycobacterium bovis BCG str. Mexico putative glycerolphosphodiesterase YP_005171742.1 2506941 R 717522 CDS YP_005171743.1 378772010 11810571 2508019..2509398 1 NC_016804.1 putative dehydrogenase 2509398 11810571 BCGMEX_2283 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005171743.1 2508019 D 717522 CDS YP_005171744.1 378772011 11810572 2509632..2511290 1 NC_016804.1 putative phosphate-transport permease 2511290 pitB 11810572 pitB Mycobacterium bovis BCG str. Mexico putative phosphate-transport permease YP_005171744.1 2509632 D 717522 CDS YP_005171745.1 378772012 11810573 complement(2511397..2512335) 1 NC_016804.1 transcriptional regulator, lysR-family 2512335 11810573 BCGMEX_2285c Mycobacterium bovis BCG str. Mexico transcriptional regulator, lysR-family YP_005171745.1 2511397 R 717522 CDS YP_005171746.1 378772013 11810574 2512400..2512594 1 NC_016804.1 hypothetical protein 2512594 11810574 BCGMEX_2286 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171746.1 2512400 D 717522 CDS YP_005171747.1 378772014 11810575 2512604..2513899 1 NC_016804.1 putative esterase 2513899 lipM 11810575 lipM Mycobacterium bovis BCG str. Mexico putative esterase YP_005171747.1 2512604 D 717522 CDS YP_005171748.1 378772015 11810576 2513932..2515269 1 NC_016804.1 putative diacylglycerol O-acyltransferase 2515269 11810576 BCGMEX_2288 Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005171748.1 2513932 D 717522 CDS YP_005171749.1 378772016 11810577 complement(2515336..2515599) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2286c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, an in-frame stop codon due to a single base transition splits Rv2286c into 2 parts; hypothetical protein 2515599 11810577 BCGMEX_2289c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171749.1 2515336 R 717522 CDS YP_005171750.1 378772017 11810578 complement(2515627..2516028) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2286c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, an in-frame stop codon due to a single base transition splits Rv2286c into 2 parts; hypothetical protein 2516028 11810578 BCGMEX_2290c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171750.1 2515627 R 717522 CDS YP_005171751.1 378772018 11810579 2516162..2517790 1 NC_016804.1 putative integral membrane transport protein 2517790 yjcE 11810579 yjcE Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005171751.1 2516162 D 717522 CDS YP_005171752.1 378772019 11810580 2517787..2518164 1 NC_016804.1 hypothetical protein 2518164 11810580 BCGMEX_2292 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171752.1 2517787 D 717522 CDS YP_005171753.1 378772020 11810581 2518134..2518916 1 NC_016804.1 CDP-diacylglycerol pyrophosphatase 2518916 cdh 11810581 cdh Mycobacterium bovis BCG str. Mexico CDP-diacylglycerol pyrophosphatase YP_005171753.1 2518134 D 717522 CDS YP_005171754.1 378772021 11810582 2519058..2519213 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2290 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion, splits lppO into 2 parts, lppOa and lppOb; putative lipoprotein 2519213 lppOa 11810582 lppOa Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171754.1 2519058 D 717522 CDS YP_005171755.1 378772022 11810583 2519207..2519572 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2290 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion, splits lppO into 2 parts, lppOa and lppOb; putative lipoprotein 2519572 lppOb 11810583 lppOb Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171755.1 2519207 D 717522 CDS YP_005171756.1 378772023 11810584 2519632..2520486 1 NC_016804.1 In Mycobacterium bovis, truncation at the 5' start due to a 2 bp deletion, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico (256 aa versus 284 aa). Differs from Rv2291 by 1aa, A262E; putative thiosulfate sulfurtransferase 2520486 sseB 11810584 sseB Mycobacterium bovis BCG str. Mexico putative thiosulfate sulfurtransferase YP_005171756.1 2519632 D 717522 CDS YP_005171757.1 378772024 11810585 complement(2520487..2521491) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2293c and Rv2292c exist as 2 genes. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base insertion results in a single product; hypothetical protein 2521491 11810585 BCGMEX_2297c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171757.1 2520487 R 717522 CDS YP_005171758.1 378772025 11810586 2521786..2523009 1 NC_016804.1 putative aminotransferase 2523009 11810586 BCGMEX_2298 Mycobacterium bovis BCG str. Mexico putative aminotransferase YP_005171758.1 2521786 D 717522 CDS YP_005171759.1 378772026 11810587 2523232..2523870 1 NC_016804.1 hypothetical protein 2523870 11810587 BCGMEX_2299 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171759.1 2523232 D 717522 CDS YP_005171760.1 378772027 11810588 2523964..2524866 1 NC_016804.1 haloalkane dehalogenase 2524866 11810588 BCGMEX_2300 Mycobacterium bovis BCG str. Mexico haloalkane dehalogenase YP_005171760.1 2523964 D 717522 CDS YP_005171761.1 378772028 11810589 2524898..2525350 1 NC_016804.1 hypothetical protein 2525350 11810589 BCGMEX_2301 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171761.1 2524898 D 717522 CDS YP_005171762.1 378772029 11810590 2525542..2526513 1 NC_016804.1 hypothetical protein 2526513 11810590 BCGMEX_2302 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171762.1 2525542 D 717522 CDS YP_005171763.1 378772030 11810591 complement(2526519..2528462) 1 NC_016804.1 chaperone protein 2528462 htpG 11810591 htpG Mycobacterium bovis BCG str. Mexico chaperone protein YP_005171763.1 2526519 R 717522 CDS YP_005171764.1 378772031 11810592 complement(2528536..2529468) 1 NC_016804.1 hypothetical protein 2529468 11810592 BCGMEX_2304c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171764.1 2528536 R 717522 CDS YP_005171765.1 378772032 11810593 2529475..2530167 1 NC_016804.1 putative cutinase 2530167 cut2 11810593 cut2 Mycobacterium bovis BCG str. Mexico putative cutinase YP_005171765.1 2529475 D 717522 CDS YP_005171766.1 378772033 11810594 2530273..2530515 1 NC_016804.1 hypothetical protein 2530515 11810594 BCGMEX_2306 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171766.1 2530273 D 717522 CDS YP_005171767.1 378772034 11810595 complement(2530556..2531479) 1 NC_016804.1 putative antibiotic-resistance protein 2531479 11810595 BCGMEX_2307c Mycobacterium bovis BCG str. Mexico putative antibiotic-resistance protein YP_005171767.1 2530556 R 717522 CDS YP_005171768.1 378772035 11810596 complement(2531476..2531685) 1 NC_016804.1 hypothetical protein 2531685 11810596 BCGMEX_2308c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171768.1 2531476 R 717522 CDS YP_005171769.1 378772036 11810597 2532269..2533558 1 NC_016804.1 Differs from Rv2305 by 1aa, D148G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2533558 11810597 BCGMEX_2309 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171769.1 2532269 D 717522 CDS YP_005171770.1 378772037 11810598 2533568..2534161 1 NC_016804.1 Differs from Rv2306A by 1aa, V47I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2534161 11810598 BCGMEX_2310 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171770.1 2533568 D 717522 CDS YP_005171771.1 378772038 11810599 2533948..2534382 1 NC_016804.1 hypothetical protein 2534382 11810599 BCGMEX_2311 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171771.1 2533948 D 717522 CDS YP_005171772.1 378772039 11810600 complement(2534311..2535156) 1 NC_016804.1 Differs from Rv2307c by 2aa, T24M, W235R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2535156 11810600 BCGMEX_2312c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171772.1 2534311 R 717522 CDS YP_005171773.1 378772040 11810601 complement(2535688..2535879) 1 NC_016804.1 putative glycine rich protein 2535879 11810601 BCGMEX_2313c Mycobacterium bovis BCG str. Mexico putative glycine rich protein YP_005171773.1 2535688 R 717522 CDS YP_005171774.1 378772041 11810602 complement(2535964..2536395) 1 NC_016804.1 putative glycine rich protein 2536395 11810602 BCGMEX_2314c Mycobacterium bovis BCG str. Mexico putative glycine rich protein YP_005171774.1 2535964 R 717522 CDS YP_005171775.1 378772042 11810603 complement(2536488..2536670) 1 NC_016804.1 hypothetical protein 2536670 11810603 BCGMEX_2315c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171775.1 2536488 R 717522 CDS YP_005171776.1 378772043 11810604 2536879..2537595 1 NC_016804.1 Differs from Rv2308 by 1aa, V43G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2537595 11810604 BCGMEX_2316 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171776.1 2536879 D 717522 CDS YP_005171777.1 378772044 11810605 2537605..2537937 1 NC_016804.1 hypothetical protein 2537937 11810605 BCGMEX_2317 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171777.1 2537605 D 717522 CDS YP_005171778.1 378772045 11810607 complement(2538303..2538758) 1 NC_016804.1 putative integrase 2538758 11810607 BCGMEX_2318c Mycobacterium bovis BCG str. Mexico putative integrase YP_005171778.1 2538303 R 717522 CDS YP_005171779.1 378772046 11810608 2539505..2539792 1 NC_016804.1 Differs from Rv2309A by 1aa, K53E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2539792 11810608 BCGMEX_2319 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171779.1 2539505 D 717522 CDS YP_005171780.1 378772047 11810609 2539895..2540239 1 NC_016804.1 putative excisionase 2540239 11810609 BCGMEX_2320 Mycobacterium bovis BCG str. Mexico putative excisionase YP_005171780.1 2539895 D 717522 CDS YP_005171781.1 378772048 11810610 2540272..2540868 1 NC_016804.1 hypothetical protein 2540868 11810610 BCGMEX_2321 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171781.1 2540272 D 717522 CDS YP_005171782.1 378772049 11810611 2540946..2541215 1 NC_016804.1 hypothetical protein 2541215 11810611 BCGMEX_2322 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171782.1 2540946 D 717522 CDS YP_005171783.1 378772050 11810612 complement(2541512..2542366) 1 NC_016804.1 hypothetical protein 2542366 11810612 BCGMEX_2323c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171783.1 2541512 R 717522 CDS YP_005171784.1 378772051 11810613 complement(2542377..2543750) 1 NC_016804.1 hypothetical protein 2543750 11810613 BCGMEX_2324c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171784.1 2542377 R 717522 CDS YP_005171785.1 378772052 11810614 complement(2543747..2545264) 1 NC_016804.1 hypothetical protein 2545264 11810614 BCGMEX_2325c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171785.1 2543747 R 717522 CDS YP_005171786.1 378772053 11810615 2545298..2546170 1 NC_016804.1 Differs from Rv2316 by 1aa, L126V in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative sugar-transport integral membrane protein ABC transporter 2546170 uspA 11810615 uspA Mycobacterium bovis BCG str. Mexico putative sugar-transport integral membrane protein ABC transporter YP_005171786.1 2545298 D 717522 CDS YP_005171787.1 378772054 11810616 2546157..2546981 1 NC_016804.1 putative sugar-transport integral membrane protein ABC transporter 2546981 uspB 11810616 uspB Mycobacterium bovis BCG str. Mexico putative sugar-transport integral membrane protein ABC transporter YP_005171787.1 2546157 D 717522 CDS YP_005171788.1 378772055 11810617 2546978..2548300 1 NC_016804.1 Differs from Rv2318 by 1aa, V354L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative periplasmic sugar-binding lipoprotein 2548300 uspC 11810617 uspC Mycobacterium bovis BCG str. Mexico putative periplasmic sugar-binding lipoprotein YP_005171788.1 2546978 D 717522 CDS YP_005171789.1 378772056 11810618 complement(2548308..2549186) 1 NC_016804.1 Differs from Rv2319c and Mb2346c by 1aa, G105E in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2549186 11810618 BCGMEX_2329c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171789.1 2548308 R 717522 CDS YP_005171790.1 378772057 11810619 complement(2549183..2550613) 1 NC_016804.1 putative cationic amino acid transport integral membrane protein 2550613 rocE 11810619 rocE Mycobacterium bovis BCG str. Mexico putative cationic amino acid transport integral membrane protein YP_005171790.1 2549183 R 717522 CDS YP_005171791.1 378772058 11810620 complement(2550614..2551159) 1 NC_016804.1 putative ornithine aminotransferase 2551159 rocD2 11810620 rocD2 Mycobacterium bovis BCG str. Mexico putative ornithine aminotransferase YP_005171791.1 2550614 R 717522 CDS YP_005171792.1 378772059 11810621 complement(2551159..2551824) 1 NC_016804.1 putative ornithine aminotransferase 2551824 rocD1 11810621 rocD1 Mycobacterium bovis BCG str. Mexico putative ornithine aminotransferase YP_005171792.1 2551159 R 717522 CDS YP_005171793.1 378772060 11810622 complement(2551821..2552729) 1 NC_016804.1 Differs from Rv2323c by 1aa, T113A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2552729 11810622 BCGMEX_2333c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171793.1 2551821 R 717522 CDS YP_005171794.1 378772061 11810623 2552794..2553240 1 NC_016804.1 AsnC family transcriptional regulator 2553240 11810623 BCGMEX_2334 Mycobacterium bovis BCG str. Mexico AsnC family transcriptional regulator YP_005171794.1 2552794 D 717522 CDS YP_005171795.1 378772062 11810624 complement(2553469..2554317) 1 NC_016804.1 hypothetical protein 2554317 11810624 BCGMEX_2335c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171795.1 2553469 R 717522 CDS YP_005171796.1 378772063 11810625 complement(2554314..2556407) 1 NC_016804.1 putative transmembrane ATP-binding protein ABC transporter 2556407 11810625 BCGMEX_2336c Mycobacterium bovis BCG str. Mexico putative transmembrane ATP-binding protein ABC transporter YP_005171796.1 2554314 R 717522 CDS YP_005171797.1 378772064 11810626 2556448..2556939 1 NC_016804.1 hypothetical protein 2556939 11810626 BCGMEX_2337 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171797.1 2556448 D 717522 CDS YP_005171798.1 378772065 11810627 2557191..2558339 1 NC_016804.1 PE family protein 2558339 PE23 11810627 PE23 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171798.1 2557191 D 717522 CDS YP_005171799.1 378772066 11810628 complement(2558374..2559921) 1 NC_016804.1 putative nitrite extrusion protein 1 2559921 narK1 11810628 narK1 Mycobacterium bovis BCG str. Mexico putative nitrite extrusion protein 1 YP_005171799.1 2558374 R 717522 CDS YP_005171800.1 378772067 11810629 complement(2560155..2560682) 1 NC_016804.1 Differs from Rv2330c and Mb2357c by 1aa, A97S in BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2560682 lppP 11810629 lppP Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171800.1 2560155 R 717522 CDS YP_005171801.1 378772068 11810630 2560757..2561143 1 NC_016804.1 hypothetical protein 2561143 11810630 BCGMEX_2341 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171801.1 2560757 D 717522 CDS YP_005171802.1 378772069 11810631 2561200..2561538 1 NC_016804.1 Differs from Rv2331A by 1aa, L46I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2561538 11810631 BCGMEX_2342 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171802.1 2561200 D 717522 CDS YP_005171803.1 378772070 11810632 2561568..2563214 1 NC_016804.1 Differs from Rv2332 by 2aa, D62E, L329I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative [NAD] dependent malate oxidoreductase 2563214 mez 11810632 mez Mycobacterium bovis BCG str. Mexico putative [NAD] dependent malate oxidoreductase YP_005171803.1 2561568 D 717522 CDS YP_005171804.1 378772071 11810633 complement(2563211..2564782) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, single base insertion leads to a slightly longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (523 aa versus 537 aa). Also differs from Rv2333c by 2aa, Y69D, Q503H in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane transport protein 2564782 11810633 BCGMEX_2344c Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005171804.1 2563211 R 717522 CDS YP_005171805.1 378772072 11810634 2565257..2566189 1 NC_016804.1 cysteine synthase 2566189 cysK1 11810634 cysK1 Mycobacterium bovis BCG str. Mexico cysteine synthase YP_005171805.1 2565257 D 717522 CDS YP_005171806.1 378772073 11810635 2566193..2566882 1 NC_016804.1 putative serine acetyltransferase 2566882 11810635 BCGMEX_2346 Mycobacterium bovis BCG str. Mexico putative serine acetyltransferase YP_005171806.1 2566193 D 717522 CDS YP_005171807.1 378772074 11810636 2567298..2568266 1 NC_016804.1 hypothetical protein 2568266 11810636 BCGMEX_2347 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171807.1 2567298 D 717522 CDS YP_005171808.1 378772075 11810637 complement(2568330..2569448) 1 NC_016804.1 Differs from Rv2337c by 1aa, V119G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2569448 11810637 BCGMEX_2348c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171808.1 2568330 R 717522 CDS YP_005171809.1 378772076 11810638 complement(2569568..2570524) 1 NC_016804.1 putative molybdopterin biosynthesis protein moeW 2570524 moeW 11810638 moeW Mycobacterium bovis BCG str. Mexico putative molybdopterin biosynthesis protein moeW YP_005171809.1 2569568 R 717522 CDS YP_005171810.1 378772077 11810639 2571155..2573635 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, mmpL9 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transition splits mmpL9 into 2 parts, mmpL9a and mmpL9b; putative transmembrane transport protein 2573635 mmpL9a 11810639 mmpL9a Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005171810.1 2571155 D 717522 CDS YP_005171811.1 378772078 11810640 2573648..2574043 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, mmpL9 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transition splits mmpL9 into 2 parts, mmpL9a and mmpL9b; putative transmembrane transport protein 2574043 mmpL9b 11810640 mmpL9b Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005171811.1 2573648 D 717522 CDS YP_005171812.1 378772079 11810641 complement(2574129..2575370) 1 NC_016804.1 Differs from Rv2340c and Mb2369c by 1aa, T222D in BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 2575370 PE_PGRS39 11810641 PE_PGRS39 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171812.1 2574129 R 717522 CDS YP_005171813.1 378772080 11810643 2576059..2576478 1 NC_016804.1 putative lipoprotein lppQ 2576478 lppQ 11810643 lppQ Mycobacterium bovis BCG str. Mexico putative lipoprotein lppQ YP_005171813.1 2576059 D 717522 CDS YP_005171814.1 378772081 11810644 2576734..2576991 1 NC_016804.1 hypothetical protein 2576991 11810644 BCGMEX_2354 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171814.1 2576734 D 717522 CDS YP_005171815.1 378772082 11810645 complement(2576995..2578914) 1 NC_016804.1 Differs from Rv2343c and Mb2372c by 1aa, R589G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative DNA primase 2578914 dnaG 11810645 dnaG Mycobacterium bovis BCG str. Mexico putative DNA primase YP_005171815.1 2576995 R 717522 CDS YP_005171816.1 378772083 11810646 complement(2578919..2580214) 1 NC_016804.1 putative Deoxyguanosinetriphosphate triphosphohydrolase 2580214 dgt 11810646 dgt Mycobacterium bovis BCG str. Mexico putative Deoxyguanosinetriphosphate triphosphohydrolase YP_005171816.1 2578919 R 717522 CDS YP_005171817.1 378772084 11810647 2580283..2582265 1 NC_016804.1 putative transmembrane protein 2582265 11810647 BCGMEX_2357 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171817.1 2580283 D 717522 CDS YP_005171818.1 378772085 11810648 complement(2582350..2582532) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a large 8963 bp deletion (RD5) leads to the loss of the NH2 part of Rv2346c, and the 9 following CDSs up to Rv2356 including the 3 phospolipases C enzymes plcC, plcB and plcA, compared to the homolog in Mycobacterium tuberculosis H37Rv; putative EsaT-6 like protein 6 2582532 esxO 11810648 esxO Mycobacterium bovis BCG str. Mexico putative EsaT-6 like protein 6 YP_005171818.1 2582350 R 717522 CDS YP_005171819.1 378772086 11810649 complement(2582516..2583922) 1 NC_016804.1 Compared to Mycobacterium bovis, there has been a 2579bp bp deletion, this has resulted in an in-frame fusion of the 5'-end of PPE40 with the 3'-end of PPE71 probably due to a homologous recombination event between codons 68 and 174 of PPE40 as the PPE40 and PPE71 genes have identical 5'-ends. Differs from Mb2376c(PPE71) by extra 11aa, insertion of A at position 68 due to 3bp insertion (present in PPE40) and STNVGSGNIG at position 307 due to 30 bp insertion. M. bovis BCG Pasteur, BCG Tokyo and BCG Mexico thus has three copies of tandem repeat STNVGSGNIG compared to two in Mb2376c. The 3'-end of PPE71 of M. bovis BCG Pasteur, BCG Tokyo and BCG Mexico have also been truncated as a result of the same deletion described in In Mycobacterium bovis, 8963 bp deletion (RD5); PPE family protein 2583922 PPE71 11810649 PPE71 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171819.1 2582516 R 717522 CDS YP_005171820.1 378772087 11810650 complement(2584060..2585451) 1 NC_016804.1 glycyl-tRNA synthetase 2585451 glyS 11810650 glyS Mycobacterium bovis BCG str. Mexico glycyl-tRNA synthetase YP_005171820.1 2584060 R 717522 CDS YP_005171821.1 378772088 11810651 2585633..2586040 1 NC_016804.1 putative transcriptional regulatory protein, probably ArsR-family 2586040 11810651 BCGMEX_2361 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, probably ArsR-family YP_005171821.1 2585633 D 717522 CDS YP_005171822.1 378772089 11810652 2586037..2586429 1 NC_016804.1 Differs from Rv2359 by 1aa, R64H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ferric uptake regulation protein 2586429 furB 11810652 furB Mycobacterium bovis BCG str. Mexico putative ferric uptake regulation protein YP_005171822.1 2586037 D 717522 CDS YP_005171823.1 378772090 11810653 complement(2586537..2586965) 1 NC_016804.1 Differs from Rv2360c by 1aa, T66A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2586965 11810653 BCGMEX_2363c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171823.1 2586537 R 717522 CDS YP_005171824.1 378772091 11810654 complement(2586965..2587855) 1 NC_016804.1 undecaprenyl pyrophosphate synthetase 2587855 uppS 11810654 uppS Mycobacterium bovis BCG str. Mexico undecaprenyl pyrophosphate synthetase YP_005171824.1 2586965 R 717522 CDS YP_005171825.1 378772092 11810655 complement(2587848..2588645) 1 NC_016804.1 DNA recombination and repair protein 2588645 recO 11810655 recO Mycobacterium bovis BCG str. Mexico DNA recombination and repair protein YP_005171825.1 2587848 R 717522 CDS YP_005171826.1 378772093 11810656 2588707..2590161 1 NC_016804.1 amidase 2590161 amiA2 11810656 amiA2 Mycobacterium bovis BCG str. Mexico amidase YP_005171826.1 2588707 D 717522 CDS YP_005171827.1 378772094 11810657 complement(2590158..2591060) 1 NC_016804.1 GTP-binding protein 2591060 era 11810657 era Mycobacterium bovis BCG str. Mexico GTP-binding protein YP_005171827.1 2590158 R 717522 CDS YP_005171828.1 378772095 11810658 complement(2591134..2591475) 1 NC_016804.1 hypothetical protein 2591475 11810658 BCGMEX_2368c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171828.1 2591134 R 717522 CDS YP_005171829.1 378772096 11810659 complement(2591447..2592754) 1 NC_016804.1 putative transmembrane protein 2592754 11810659 BCGMEX_2369c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171829.1 2591447 R 717522 CDS YP_005171830.1 378772097 11810660 complement(2592751..2593299) 1 NC_016804.1 putative metalloprotease 2593299 11810660 BCGMEX_2370c Mycobacterium bovis BCG str. Mexico putative metalloprotease YP_005171830.1 2592751 R 717522 CDS YP_005171831.1 378772098 11810661 complement(2593303..2594361) 1 NC_016804.1 putative phoH-like protein 2594361 phoH1 11810661 phoH1 Mycobacterium bovis BCG str. Mexico putative phoH-like protein YP_005171831.1 2593303 R 717522 CDS YP_005171832.1 378772099 11810662 complement(2594333..2594635) 1 NC_016804.1 hypothetical protein 2594635 11810662 BCGMEX_2372c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171832.1 2594333 R 717522 CDS YP_005171833.1 378772100 11810663 complement(2594632..2595945) 1 NC_016804.1 hypothetical protein 2595945 11810663 BCGMEX_2373c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171833.1 2594632 R 717522 CDS YP_005171834.1 378772101 11810664 2596140..2596325 1 NC_016804.1 PE-PGRS family protein 2596325 PE_PGRS40 11810664 PE_PGRS40 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171834.1 2596140 D 717522 CDS YP_005171835.1 378772102 11810665 complement(2596424..2597212) 1 NC_016804.1 ribosomal RNA small subunit methyltransferase E 2597212 rsmE 11810665 rsmE Mycobacterium bovis BCG str. Mexico ribosomal RNA small subunit methyltransferase E YP_005171835.1 2596424 R 717522 CDS YP_005171836.1 378772103 11810666 complement(2597226..2598374) 1 NC_016804.1 chaperone protein 2598374 dnaJ2 11810666 dnaJ2 Mycobacterium bovis BCG str. Mexico chaperone protein YP_005171836.1 2597226 R 717522 CDS YP_005171837.1 378772104 11810667 complement(2598449..2599480) 1 NC_016804.1 Differs from Rv2374c and Mb2395c by 1aa, Q79R in BCG Pasteur, BCG Tokio and BCG Mexico; heat-inducible transcriptional repressor 2599480 hrcA 11810667 hrcA Mycobacterium bovis BCG str. Mexico heat-inducible transcriptional repressor YP_005171837.1 2598449 R 717522 CDS YP_005171838.1 378772105 11810668 2599652..2599969 1 NC_016804.1 hypothetical protein 2599969 11810668 BCGMEX_2378 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171838.1 2599652 D 717522 CDS YP_005171839.1 378772106 11810669 complement(2599996..2600502) 1 NC_016804.1 Low molecular weight antigen 2600502 cfp2 11810669 cfp2 Mycobacterium bovis BCG str. Mexico Low molecular weight antigen YP_005171839.1 2599996 R 717522 CDS YP_005171840.1 378772107 11810670 complement(2600602..2600817) 1 NC_016804.1 Differs from Rv2377c by 1aa, A69V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative protein mbtH 2600817 mbtH 11810670 mbtH Mycobacterium bovis BCG str. Mexico putative protein mbtH YP_005171840.1 2600602 R 717522 CDS YP_005171841.1 378772108 11810671 complement(2600795..2602090) 1 NC_016804.1 L-lysine 6-monooxygenase 2602090 mbtG 11810671 mbtG Mycobacterium bovis BCG str. Mexico L-lysine 6-monooxygenase YP_005171841.1 2600795 R 717522 CDS YP_005171842.1 378772109 11810672 complement(2602087..2606472) 1 NC_016804.1 Differs from Rv2379c by 1aa, D589E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; peptide synthetase 2606472 mbtF 11810672 mbtF Mycobacterium bovis BCG str. Mexico peptide synthetase YP_005171842.1 2602087 R 717522 CDS YP_005171843.1 378772110 11810673 complement(2606454..2611502) 1 NC_016804.1 peptide synthetase 2611502 mbtE 11810673 mbtE Mycobacterium bovis BCG str. Mexico peptide synthetase YP_005171843.1 2606454 R 717522 CDS YP_005171844.1 378772111 11810674 complement(2611642..2614656) 1 NC_016804.1 polyketide synthase 2614656 mbtD 11810674 mbtD Mycobacterium bovis BCG str. Mexico polyketide synthase YP_005171844.1 2611642 R 717522 CDS YP_005171845.1 378772112 11810675 complement(2614656..2615990) 1 NC_016804.1 polyketide synthetase 2615990 mbtC 11810675 mbtC Mycobacterium bovis BCG str. Mexico polyketide synthetase YP_005171845.1 2614656 R 717522 CDS YP_005171846.1 378772113 11810676 complement(2615980..2620224) 1 NC_016804.1 Differs from Rv2383c by 2aa, Q264R, P1253T, and from Mb2404c by 1aa, P1253T BCG Pasteur, BCG Tokyo and BCG Mexico; phenyloxazoline synthase 2620224 mbtB 11810676 mbtB Mycobacterium bovis BCG str. Mexico phenyloxazoline synthase YP_005171846.1 2615980 R 717522 CDS YP_005171847.1 378772114 11810677 2620323..2622020 1 NC_016804.1 bifunctional enzyme mbtA: salicyl-AMP ligase/salicyl-S-arcp synthetase 2622020 mbtA 11810677 mbtA Mycobacterium bovis BCG str. Mexico bifunctional enzyme mbtA: salicyl-AMP ligase/salicyl-S-arcp synthetase YP_005171847.1 2620323 D 717522 CDS YP_005171848.1 378772115 11810678 2622116..2623036 1 NC_016804.1 putative acetyl hydrolase 2623036 mbtJ 11810678 mbtJ Mycobacterium bovis BCG str. Mexico putative acetyl hydrolase YP_005171848.1 2622116 D 717522 CDS YP_005171849.1 378772116 11810679 complement(2623040..2624392) 1 NC_016804.1 isochorismate synthase 2624392 mbtI 11810679 mbtI Mycobacterium bovis BCG str. Mexico isochorismate synthase YP_005171849.1 2623040 R 717522 CDS YP_005171850.1 378772117 11810680 2624845..2625054 1 NC_016804.1 hypothetical protein 2625054 11810680 BCGMEX_2390 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171850.1 2624845 D 717522 CDS YP_005171851.1 378772118 11810681 2625152..2626405 1 NC_016804.1 hypothetical protein 2626405 11810681 BCGMEX_2391 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171851.1 2625152 D 717522 CDS YP_005171852.1 378772119 11810682 complement(2626402..2627529) 1 NC_016804.1 Differs from Rv2388c, by 1aa, T184A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Coproporphyrinogen III oxidase 2627529 hemN 11810682 hemN Mycobacterium bovis BCG str. Mexico Coproporphyrinogen III oxidase YP_005171852.1 2626402 R 717522 CDS YP_005171853.1 378772120 11810683 complement(2627635..2628099) 1 NC_016804.1 putative resuscitation-promoting factor 2628099 rpfD 11810683 rpfD Mycobacterium bovis BCG str. Mexico putative resuscitation-promoting factor YP_005171853.1 2627635 R 717522 CDS YP_005171854.1 378772121 11810684 complement(2628096..2628653) 1 NC_016804.1 Differs from Mb2411c by 1aa, I33T in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2628653 11810684 BCGMEX_2394c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171854.1 2628096 R 717522 CDS YP_005171855.1 378772122 11810685 2629090..2630757 1 NC_016804.1 sulfite reductase 2630757 nirA 11810685 nirA Mycobacterium bovis BCG str. Mexico sulfite reductase YP_005171855.1 2629090 D 717522 CDS YP_005171856.1 378772123 11810686 2630754..2631518 1 NC_016804.1 phosphoadenosine phosphosulfate reductase 2631518 cysH 11810686 cysH Mycobacterium bovis BCG str. Mexico phosphoadenosine phosphosulfate reductase YP_005171856.1 2630754 D 717522 CDS YP_005171857.1 378772124 11810687 2631515..2632414 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, duplication of 54 bp segment after codon 3 leads to additional 18 aa and two tandem copies of motif PATMQSAAMLRSGAIEAP, compared to its ortholog in Mycobacterium tuberculosis strain H37Rv and in Mycobacterium bovis AF2122/97; hypothetical protein 2632414 11810687 BCGMEX_2397 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171857.1 2631515 D 717522 CDS YP_005171858.1 378772125 11810688 2632451..2634382 1 NC_016804.1 Differs from Rv2394 by 1aa Q396R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative gamma-glutamyltranspeptidase 2634382 ggtB 11810688 ggtB Mycobacterium bovis BCG str. Mexico putative gamma-glutamyltranspeptidase YP_005171858.1 2632451 D 717522 CDS YP_005171859.1 378772126 11810689 2634513..2634953 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2395 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, as in Mycobacterium bovis, a frameshift due to a single base insertion splits Rv2395 into 2 parts. The frameshift occurs after the 44th codon; putative integral membrane protein 2634953 11810689 BCGMEX_2399 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171859.1 2634513 D 717522 CDS YP_005171860.1 378772127 11810690 2634967..2636517 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2395 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base insertion splits Rv2395 into 2 parts. BCG_2410 also differs from Rv2395 by 1aa, P396S in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 2636517 11810690 BCGMEX_2400 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171860.1 2634967 D 717522 CDS YP_005171861.1 378772128 11810691 2637241..2638323 1 NC_016804.1 similar to Mb2418 of Mycobacterium bovis, including 3 bp deletion that leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (360 aa versus 361 aa) due to deletion of A95 in BCG Pasteur, BCG Tokyo and BCG Mexico. Also differs from Rv2396 by 2aa, N26S, S324N in BCG Pasteur and BCG Mexico. Differs from Rv2396 by 3aa, N26S, C218G, S324N in BCG Tokyo; PE-PGRS family protein 2638323 PE_PGRS41 11810691 PE_PGRS41 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171861.1 2637241 D 717522 CDS YP_005171862.1 378772129 11810692 complement(2638348..2639403) 1 NC_016804.1 sulfate/thiosulfate import ATP-binding protein 2639403 cysA1 11810692 cysA1 Mycobacterium bovis BCG str. Mexico sulfate/thiosulfate import ATP-binding protein YP_005171862.1 2638348 R 717522 CDS YP_005171863.1 378772130 11810693 complement(2639420..2640238) 1 NC_016804.1 Differs from Rv2398c by 1aa, A141G, and from Mb2420c by 1aa, R264H in BCG Pasteur, BCG Tokyo and BCG Mexico; putative sulfate-transport integral membrane protein ABC transporter 2640238 cysW 11810693 cysW Mycobacterium bovis BCG str. Mexico putative sulfate-transport integral membrane protein ABC transporter YP_005171863.1 2639420 R 717522 CDS YP_005171864.1 378772131 11810694 complement(2640235..2641086) 1 NC_016804.1 putative sulfate-transport integral membrane protein ABC transporter 2641086 cysT 11810694 cysT Mycobacterium bovis BCG str. Mexico putative sulfate-transport integral membrane protein ABC transporter YP_005171864.1 2640235 R 717522 CDS YP_005171865.1 378772132 11810695 complement(2641083..2642153) 1 NC_016804.1 putative sulfate-binding lipoprotein 2642153 subI 11810695 subI Mycobacterium bovis BCG str. Mexico putative sulfate-binding lipoprotein YP_005171865.1 2641083 R 717522 CDS YP_005171866.1 378772133 11810696 2642167..2642496 1 NC_016804.1 hypothetical protein 2642496 11810696 BCGMEX_2406 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171866.1 2642167 D 717522 CDS YP_005171867.1 378772134 11810697 complement(2642481..2642684) 1 NC_016804.1 hypothetical protein 2642684 11810697 BCGMEX_2407c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171867.1 2642481 R 717522 CDS YP_005171868.1 378772135 11810698 2642968..2644896 1 NC_016804.1 hypothetical protein 2644896 11810698 BCGMEX_2408 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171868.1 2642968 D 717522 CDS YP_005171869.1 378772136 11810699 complement(2644974..2645729) 1 NC_016804.1 Differs from Rv2403c by 1aa, L127V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2645729 lppR 11810699 lppR Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171869.1 2644974 R 717522 CDS YP_005171870.1 378772137 11810700 complement(2645726..2647687) 1 NC_016804.1 GTP-binding protein 2647687 lepA 11810700 lepA Mycobacterium bovis BCG str. Mexico GTP-binding protein YP_005171870.1 2645726 R 717522 CDS YP_005171871.1 378772138 11810701 2647708..2648277 1 NC_016804.1 hypothetical protein 2648277 11810701 BCGMEX_2411 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171871.1 2647708 D 717522 CDS YP_005171872.1 378772139 11810702 complement(2648448..2648876) 1 NC_016804.1 hypothetical protein 2648876 11810702 BCGMEX_2412c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171872.1 2648448 R 717522 CDS YP_005171873.1 378772140 11810703 2649136..2649978 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 21 bp in-frame insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (280 aa versus 273 aa). Also differs from both Mb2430 and Rv2407 by 1aa, R222Q in BCG Pasteur, BCG Tokyo and BCG Mexico; ribonuclease Z 2649978 11810703 BCGMEX_2413 Mycobacterium bovis BCG str. Mexico ribonuclease Z YP_005171873.1 2649136 D 717522 CDS YP_005171874.1 378772141 11810704 2650571..2651290 1 NC_016804.1 putative PE family-related protein 2651290 11810704 BCGMEX_2414 Mycobacterium bovis BCG str. Mexico putative PE family-related protein YP_005171874.1 2650571 D 717522 CDS YP_005171875.1 378772142 11810705 complement(2651048..2651887) 1 NC_016804.1 hypothetical protein 2651887 11810705 BCGMEX_2415c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171875.1 2651048 R 717522 CDS YP_005171876.1 378772143 11810706 complement(2651887..2652864) 1 NC_016804.1 hypothetical protein 2652864 11810706 BCGMEX_2416c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171876.1 2651887 R 717522 CDS YP_005171877.1 378772144 11810707 complement(2652864..2654519) 1 NC_016804.1 hypothetical protein 2654519 11810707 BCGMEX_2417c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171877.1 2652864 R 717522 CDS YP_005171878.1 378772145 11810708 2654629..2654889 1 NC_016804.1 30S ribosomal protein S20 2654889 rpsT 11810708 rpsT Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S20 YP_005171878.1 2654629 D 717522 CDS YP_005171879.1 378772146 11810709 complement(2654905..2655873) 1 NC_016804.1 hypothetical protein 2655873 11810709 BCGMEX_2419c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171879.1 2654905 R 717522 CDS YP_005171880.1 378772147 11810710 complement(2655886..2657430) 1 NC_016804.1 In Mycobacterium bovis, a single base insertion leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico (523 aa versus 514 aa); hypothetical protein 2657430 11810710 BCGMEX_2420c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171880.1 2655886 R 717522 CDS YP_005171881.1 378772148 11810711 complement(2657445..2658338) 1 NC_016804.1 Differs from Rv2415c by 1aa, L291R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2658338 11810711 BCGMEX_2421c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171881.1 2657445 R 717522 CDS YP_005171882.1 378772149 11810712 complement(2658678..2659904) 1 NC_016804.1 Differs from Mb2439c by 1aa, T76A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Enhanced intracellular survival protein 2659904 eis 11810712 eis Mycobacterium bovis BCG str. Mexico Enhanced intracellular survival protein YP_005171882.1 2658678 R 717522 CDS YP_005171883.1 378772150 11810713 complement(2660026..2660868) 1 NC_016804.1 hypothetical protein 2660868 11810713 BCGMEX_2423c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171883.1 2660026 R 717522 CDS YP_005171884.1 378772151 11810714 complement(2660949..2661692) 1 NC_016804.1 hypothetical protein 2661692 11810714 BCGMEX_2424c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171884.1 2660949 R 717522 CDS YP_005171885.1 378772152 11810715 complement(2661682..2662353) 1 NC_016804.1 Differs from Mb2442c by 1aa, A165V in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative phosphoglycerate mutase 2662353 11810715 BCGMEX_2425c Mycobacterium bovis BCG str. Mexico putative phosphoglycerate mutase YP_005171885.1 2661682 R 717522 CDS YP_005171886.1 378772153 11810716 complement(2662350..2662733) 1 NC_016804.1 Differs from Rv2420c and Mb2443c by insertion of 1aa, Pro, at position 126 due to 3bp insertion in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2662733 11810716 BCGMEX_2426c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171886.1 2662350 R 717522 CDS YP_005171887.1 378772154 11810717 complement(2662730..2663365) 1 NC_016804.1 Differs from Rv2421c by 1aa, S180G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; nicotinate-nucleotide adenylyltransferase 2663365 nadD 11810717 nadD Mycobacterium bovis BCG str. Mexico nicotinate-nucleotide adenylyltransferase YP_005171887.1 2662730 R 717522 CDS YP_005171888.1 378772155 11810718 2663640..2663912 1 NC_016804.1 hypothetical protein 2663912 11810718 BCGMEX_2428 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171888.1 2663640 D 717522 CDS YP_005171889.1 378772156 11810719 2664154..2665200 1 NC_016804.1 hypothetical protein 2665200 11810719 BCGMEX_2429 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171889.1 2664154 D 717522 CDS YP_005171890.1 378772157 11810720 complement(2665333..2666025) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2424c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 2bp deletion splits Rv2424c into 2 parts. Differs from Rv2424c by 3aa, I172T, A173T and Y192H; putative transposase, IS1558 2666025 11810720 BCGMEX_2430c Mycobacterium bovis BCG str. Mexico putative transposase, IS1558 YP_005171890.1 2665333 R 717522 CDS YP_005171891.1 378772158 11810721 complement(2666039..2666332) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2424c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 2bp deletion splits Rv2424c into 2 parts; putative transposase 2666332 11810721 BCGMEX_2431c Mycobacterium bovis BCG str. Mexico putative transposase YP_005171891.1 2666039 R 717522 CDS YP_005171892.1 378772159 11810722 complement(2666421..2667863) 1 NC_016804.1 hypothetical protein 2667863 11810722 BCGMEX_2432c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171892.1 2666421 R 717522 CDS YP_005171893.1 378772160 11810723 complement(2667863..2668738) 1 NC_016804.1 Differs from Rv2426c by 1aa, L113F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2668738 11810723 BCGMEX_2433c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171893.1 2667863 R 717522 CDS YP_005171894.1 378772161 11810724 complement(2668765..2670012) 1 NC_016804.1 gamma-glutamyl phosphate reductase 2670012 proA 11810724 proA Mycobacterium bovis BCG str. Mexico gamma-glutamyl phosphate reductase YP_005171894.1 2668765 R 717522 CDS YP_005171895.1 378772162 11810727 2670728..2671315 1 NC_016804.1 alkyl hydroperoxide reductase protein C 2671315 ahpC 11810727 ahpC Mycobacterium bovis BCG str. Mexico alkyl hydroperoxide reductase protein C YP_005171895.1 2670728 D 717522 CDS YP_005171896.1 378772163 11810728 2671341..2671874 1 NC_016804.1 alkylhydroperoxidase reductase protein D 2671874 ahpD 11810728 ahpD Mycobacterium bovis BCG str. Mexico alkylhydroperoxidase reductase protein D YP_005171896.1 2671341 D 717522 CDS YP_005171897.1 378772164 11810729 complement(2671871..2672455) 1 NC_016804.1 PPE family protein 2672455 PPE41 11810729 PPE41 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005171897.1 2671871 R 717522 CDS YP_005171898.1 378772165 11810730 complement(2672502..2672801) 1 NC_016804.1 PE family protein 2672801 PE25 11810730 PE25 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171898.1 2672502 R 717522 CDS YP_005171899.1 378772166 11810731 complement(2672972..2673382) 1 NC_016804.1 hypothetical protein 2673382 11810731 BCGMEX_2441c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171899.1 2672972 R 717522 CDS YP_005171900.1 378772167 11810732 complement(2673379..2673669) 1 NC_016804.1 hypothetical protein 2673669 11810732 BCGMEX_2442c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171900.1 2673379 R 717522 CDS YP_005171901.1 378772168 11810733 complement(2673650..2675095) 1 NC_016804.1 putative transmembrane protein 2675095 11810733 BCGMEX_2443c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005171901.1 2673650 R 717522 CDS YP_005171902.1 378772169 11810734 complement(2675092..2677284) 1 NC_016804.1 putative adenylate cyclase 2677284 11810734 BCGMEX_2444c Mycobacterium bovis BCG str. Mexico putative adenylate cyclase YP_005171902.1 2675092 R 717522 CDS YP_005171903.1 378772170 11810735 2677765..2678679 1 NC_016804.1 Differs from Rv2436 by 2aa, V274A, A282V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ribokinase 2678679 rbsK 11810735 rbsK Mycobacterium bovis BCG str. Mexico ribokinase YP_005171903.1 2677765 D 717522 CDS YP_005171904.1 378772171 11810736 2678911..2679330 1 NC_016804.1 hypothetical protein 2679330 11810736 BCGMEX_2446 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171904.1 2678911 D 717522 CDS YP_005171905.1 378772172 11810737 complement(2679327..2681366) 1 NC_016804.1 NAD synthetase 2681366 nadE 11810737 nadE Mycobacterium bovis BCG str. Mexico NAD synthetase YP_005171905.1 2679327 R 717522 CDS YP_005171906.1 378772173 11810738 2681244..2681522 1 NC_016804.1 hypothetical protein 2681522 11810738 BCGMEX_2448 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171906.1 2681244 D 717522 CDS YP_005171907.1 378772174 11810739 complement(2681652..2682782) 1 NC_016804.1 Differs from Rv2439c by 1aa, S226A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; glutamate 5-kinase 2682782 proB 11810739 proB Mycobacterium bovis BCG str. Mexico glutamate 5-kinase YP_005171907.1 2681652 R 717522 CDS YP_005171908.1 378772175 11810740 complement(2682782..2684221) 1 NC_016804.1 GTPase 2684221 obg 11810740 obg Mycobacterium bovis BCG str. Mexico GTPase YP_005171908.1 2682782 R 717522 CDS YP_005171909.1 378772176 11810741 complement(2684307..2684567) 1 NC_016804.1 50S ribosomal protein L27 2684567 rpmA 11810741 rpmA Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L27 YP_005171909.1 2684307 R 717522 CDS YP_005171910.1 378772177 11810742 complement(2684582..2684896) 1 NC_016804.1 50S ribosomal protein L21 2684896 rplU 11810742 rplU Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L21 YP_005171910.1 2684582 R 717522 CDS YP_005171911.1 378772178 11810743 2685244..2686719 1 NC_016804.1 putative C4-dicarboxylate-transport transmembrane protein 2686719 dctA 11810743 dctA Mycobacterium bovis BCG str. Mexico putative C4-dicarboxylate-transport transmembrane protein YP_005171911.1 2685244 D 717522 CDS YP_005171912.1 378772179 11810744 complement(2686658..2689519) 1 NC_016804.1 putative ribonuclease E 2689519 rne 11810744 rne Mycobacterium bovis BCG str. Mexico putative ribonuclease E YP_005171912.1 2686658 R 717522 CDS YP_005171913.1 378772180 11810745 complement(2689849..2690259) 1 NC_016804.1 nucleoside diphosphate kinase 2690259 ndkA 11810745 ndkA Mycobacterium bovis BCG str. Mexico nucleoside diphosphate kinase YP_005171913.1 2689849 R 717522 CDS YP_005171914.1 378772181 11810746 complement(2690302..2690673) 1 NC_016804.1 putative integral membrane protein 2690673 11810746 BCGMEX_2456c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005171914.1 2690302 R 717522 CDS YP_005171915.1 378772182 11810747 complement(2690670..2692133) 1 NC_016804.1 putative polylpolyglutamate synthase 2692133 folC 11810747 folC Mycobacterium bovis BCG str. Mexico putative polylpolyglutamate synthase YP_005171915.1 2690670 R 717522 CDS YP_005171916.1 378772183 11810748 complement(2692130..2694760) 1 NC_016804.1 valyl-tRNA synthetase 2694760 valS 11810748 valS Mycobacterium bovis BCG str. Mexico valyl-tRNA synthetase YP_005171916.1 2692130 R 717522 CDS YP_005171917.1 378772184 11810749 complement(2694848..2696107) 1 NC_016804.1 Differs from Rv2449c and Mb2476c by 1aa, C273R in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2696107 11810749 BCGMEX_2459c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171917.1 2694848 R 717522 CDS YP_005171918.1 378772185 11810750 complement(2696197..2696715) 1 NC_016804.1 Differs from Rv2450c by 1aa, Q126R in BCG Pasteur and BCG Mexico; putative resuscitation-promoting factor 2696715 rpfE 11810750 rpfE Mycobacterium bovis BCG str. Mexico putative resuscitation-promoting factor YP_005171918.1 2696197 R 717522 CDS YP_005171919.1 378772186 11810751 2696797..2697195 1 NC_016804.1 Differs from Rv2451 by 1aa, D63N in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative proline and serine rich protein 2697195 11810751 BCGMEX_2461 Mycobacterium bovis BCG str. Mexico putative proline and serine rich protein YP_005171919.1 2696797 D 717522 CDS YP_005171920.1 378772187 11810752 complement(2697383..2697529) 1 NC_016804.1 hypothetical protein 2697529 11810752 BCGMEX_2462c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171920.1 2697383 R 717522 CDS YP_005171921.1 378772188 11810753 complement(2697553..2698158) 1 NC_016804.1 putative molybdopterin-guanine dinucleotide biosynthesis protein A 2698158 mobA 11810753 mobA Mycobacterium bovis BCG str. Mexico putative molybdopterin-guanine dinucleotide biosynthesis protein A YP_005171921.1 2697553 R 717522 CDS YP_005171922.1 378772189 11810754 complement(2698160..2699281) 1 NC_016804.1 2-oxoglutarate ferrodoxin oxidoreductase subunit beta 2699281 11810754 BCGMEX_2464c Mycobacterium bovis BCG str. Mexico 2-oxoglutarate ferrodoxin oxidoreductase subunit beta YP_005171922.1 2698160 R 717522 CDS YP_005171923.1 378772190 11810755 complement(2699278..2701239) 1 NC_016804.1 putative oxidoreductase subunit alpha 2701239 11810755 BCGMEX_2465c Mycobacterium bovis BCG str. Mexico putative oxidoreductase subunit alpha YP_005171923.1 2699278 R 717522 CDS YP_005171924.1 378772191 11810756 complement(2701471..2702727) 1 NC_016804.1 putative integral membrane transport protein 2702727 11810756 BCGMEX_2466c Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005171924.1 2701471 R 717522 CDS YP_005171925.1 378772192 11810757 complement(2702743..2704023) 1 NC_016804.1 Differs from Rv2457c and Mb2484c by 1aa, A229G in BCG Pasteur, BCG Tokyo and BCG Mexico. Also differs from Rv2457c and Mb2484c by 1aa, A403V in BCG Mexico; ATP-dependent Clp protease ATP-binding subunit clpX 2704023 clpX 11810757 clpX Mycobacterium bovis BCG str. Mexico ATP-dependent Clp protease ATP-binding subunit clpX YP_005171925.1 2702743 R 717522 CDS YP_005171926.1 378772193 11810758 2704314..2705222 1 NC_016804.1 Differs from Rv2458 by 1aa, C125Y in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; homocysteine S-methyltransferase 2705222 mmuM 11810758 mmuM Mycobacterium bovis BCG str. Mexico homocysteine S-methyltransferase YP_005171926.1 2704314 D 717522 CDS YP_005171927.1 378772194 11810759 2705389..2706915 1 NC_016804.1 Differs from Mb2486 by 1aa, M55I in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane transport protein 2706915 11810759 BCGMEX_2469 Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005171927.1 2705389 D 717522 CDS YP_005171928.1 378772195 11810760 complement(2707066..2707710) 1 NC_016804.1 ATP-dependent Clp protease proteolytic subunit 2707710 clpP2 11810760 clpP2 Mycobacterium bovis BCG str. Mexico ATP-dependent Clp protease proteolytic subunit YP_005171928.1 2707066 R 717522 CDS YP_005171929.1 378772196 11810761 complement(2707707..2708309) 1 NC_016804.1 ATP-dependent Clp protease proteolytic subunit 2708309 clpP 11810761 clpP Mycobacterium bovis BCG str. Mexico ATP-dependent Clp protease proteolytic subunit YP_005171929.1 2707707 R 717522 CDS YP_005171930.1 378772197 11810762 complement(2708426..2709826) 1 NC_016804.1 Differs from Rv2462c by 1aa, L118P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; trigger factor Tig 2709826 tig 11810762 tig Mycobacterium bovis BCG str. Mexico trigger factor Tig YP_005171930.1 2708426 R 717522 CDS YP_005171931.1 378772198 11810765 2710190..2711374 1 NC_016804.1 putative esterase/lipase 2711374 lipP 11810765 lipP Mycobacterium bovis BCG str. Mexico putative esterase/lipase YP_005171931.1 2710190 D 717522 CDS YP_005171932.1 378772199 11810766 complement(2711394..2712200) 1 NC_016804.1 DNA glycosylase 2712200 11810766 BCGMEX_2474c Mycobacterium bovis BCG str. Mexico DNA glycosylase YP_005171932.1 2711394 R 717522 CDS YP_005171933.1 378772200 11810767 complement(2712206..2712694) 1 NC_016804.1 ribose 5-phosphate isomerase B 2712694 rpiB 11810767 rpiB Mycobacterium bovis BCG str. Mexico ribose 5-phosphate isomerase B YP_005171933.1 2712206 R 717522 CDS YP_005171934.1 378772201 11810768 complement(2712796..2713419) 1 NC_016804.1 hypothetical protein 2713419 11810768 BCGMEX_2476c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171934.1 2712796 R 717522 CDS YP_005171935.1 378772202 11810769 2713521..2716106 1 NC_016804.1 Differs from Rv2467 and Mb2494 by 1aa, M18I in Mycobacterium bovis BCG Pasteur; putative aminopeptidase N 2716106 pepN 11810769 pepN Mycobacterium bovis BCG str. Mexico putative aminopeptidase N YP_005171935.1 2713521 D 717522 CDS YP_005171936.1 378772203 11810770 complement(2716179..2716682) 1 NC_016804.1 hypothetical protein 2716682 11810770 BCGMEX_2478c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171936.1 2716179 R 717522 CDS YP_005171937.1 378772204 11810771 complement(2716633..2716866) 1 NC_016804.1 hypothetical protein 2716866 11810771 BCGMEX_2479c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171937.1 2716633 R 717522 CDS YP_005171938.1 378772205 11810772 complement(2716902..2717570) 1 NC_016804.1 Differs from Rv2469c by 2aa, G28S, S99A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2717570 11810772 BCGMEX_2480c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171938.1 2716902 R 717522 CDS YP_005171939.1 378772206 11810773 2717713..2718099 1 NC_016804.1 Oxygen-binding protein; putative globin 2718099 glbO 11810773 glbO Mycobacterium bovis BCG str. Mexico putative globin YP_005171939.1 2717713 D 717522 CDS YP_005171940.1 378772207 11810774 2718099..2719739 1 NC_016804.1 Differs from Rv2471 by 1aa, S206W in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative alpha-glucosidase 2719739 aglA 11810774 aglA Mycobacterium bovis BCG str. Mexico putative alpha-glucosidase YP_005171940.1 2718099 D 717522 CDS YP_005171941.1 378772208 11810775 2719807..2720100 1 NC_016804.1 hypothetical protein 2720100 11810775 BCGMEX_2483 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171941.1 2719807 D 717522 CDS YP_005171942.1 378772209 11810776 2720103..2720819 1 NC_016804.1 hypothetical protein 2720819 11810776 BCGMEX_2484 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171942.1 2720103 D 717522 CDS YP_005171943.1 378772210 11810777 complement(2720851..2721504) 1 NC_016804.1 Differs from Mb2501c by 1aa, A30V in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2721504 11810777 BCGMEX_2485c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171943.1 2720851 R 717522 CDS YP_005171944.1 378772211 11810778 complement(2721510..2721926) 1 NC_016804.1 hypothetical protein 2721926 11810778 BCGMEX_2486c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171944.1 2721510 R 717522 CDS YP_005171945.1 378772212 11810779 complement(2721923..2726794) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 3 bp deletion leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (1623 aa versus 1624 aa). Differs from Rv2476c by 2aa, loss of A501 due to 3 bp deletion and G1042S; putative NAD-dependent glutamate dehydrogenase 2726794 gdh 11810779 gdh Mycobacterium bovis BCG str. Mexico putative NAD-dependent glutamate dehydrogenase YP_005171945.1 2721923 R 717522 CDS YP_005171946.1 378772213 11810780 complement(2726898..2728574) 1 NC_016804.1 Differs from Rv2477c and Mb2504c by 1aa, K372T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative ABC transporter ATP-binding protein 2728574 11810780 BCGMEX_2488c Mycobacterium bovis BCG str. Mexico putative ABC transporter ATP-binding protein YP_005171946.1 2726898 R 717522 CDS YP_005171947.1 378772214 11810781 complement(2728655..2729140) 1 NC_016804.1 ssDNA-binding protein 2729140 11810781 BCGMEX_2489c Mycobacterium bovis BCG str. Mexico ssDNA-binding protein YP_005171947.1 2728655 R 717522 CDS YP_005171948.1 378772215 11810782 complement(2729749..2730072) 1 NC_016804.1 hypothetical protein 2730072 11810782 BCGMEX_2490 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171948.1 2729749 R 717522 CDS YP_005171949.1 378772216 11810783 complement(2730088..2732457) 1 NC_016804.1 Differs from Rv2482c by 1aa, R778C, and from Mb2507c by 1aa, N579S in BCG Pasteur, BCG Tokyo and BCG Mexico; glycerol-3-phosphate acyltransferase 2732457 plsB2 11810783 plsB2 Mycobacterium bovis BCG str. Mexico glycerol-3-phosphate acyltransferase YP_005171949.1 2730088 R 717522 CDS YP_005171950.1 378772217 11810784 complement(2732454..2734196) 1 NC_016804.1 Differs from Rv2483c by 1aa, G189C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative L-3-phosphoserine phosphatase, 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative transmembrane phospholipid biosynthesis enzyme 2734196 plsC 11810784 plsC Mycobacterium bovis BCG str. Mexico putative transmembrane phospholipid biosynthesis enzyme YP_005171950.1 2732454 R 717522 CDS YP_005171951.1 378772218 11810785 complement(2734193..2735668) 1 NC_016804.1 Differs from Rv2484c by 1aa, D466G in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2735668 11810785 BCGMEX_2493c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171951.1 2734193 R 717522 CDS YP_005171952.1 378772219 11810786 complement(2735897..2737162) 1 NC_016804.1 putative carboxylesterase 2737162 lipQ 11810786 lipQ Mycobacterium bovis BCG str. Mexico putative carboxylesterase YP_005171952.1 2735897 R 717522 CDS YP_005171953.1 378772220 11810788 2737524..2738294 1 NC_016804.1 Enoyl-CoA hydratase 2738294 echA14 11810788 echA14 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005171953.1 2737524 D 717522 CDS YP_005171954.1 378772221 11810790 complement(2738974..2740557) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS42 exists as a single gene. In Mycobacterium bovis, 2 frameshifts, the first due to a single base insertion and the second due to a single base deletion splits PE_PGRS42 into 3 parts, PE_PGRS42a and PE_PGRS42b and PE_PGRS42d while in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, PE_PGRS42a and PE_GRRS42b are fused; PE-PGRS family protein 2740557 PE_PGRS42ab 11810790 PE_PGRS42ab Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171954.1 2738974 R 717522 CDS YP_005171955.1 378772222 11810791 complement(2740639..2744052) 1 NC_016804.1 Differs from Rv2488c and Mb2515c by 1aa E535D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, LuxR family 2744052 11810791 BCGMEX_2498c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, LuxR family YP_005171955.1 2740639 R 717522 CDS YP_005171956.1 378772223 11810792 complement(2744018..2744317) 1 NC_016804.1 hypothetical protein 2744317 11810792 BCGMEX_2499c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171956.1 2744018 R 717522 CDS YP_005171957.1 378772224 11810793 complement(2744426..2747878) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS43 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 8 bp insertion splits PE_PGRS43 into 2 parts, PE_PGRS43a and PE_PGRS43b while in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 1bp insertion causes a different frameshift but at same place, 3bp:GCC deletion in BCG Pasteur and BCG Mexico after 2409:G of Mycobacterium bovis, 1bp:T deletion in BCG Tokyo at 2931:T of Mycobacterium bovis; PE-PGRS family protein 2747878 PE_PGRS43b 11810793 PE_PGRS43b Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171957.1 2744426 R 717522 CDS YP_005171958.1 378772225 11810794 complement(2747970..2749397) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS43 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 8 bp insertion splits PE_PGRS43 into 2 parts, PE_PGRS43a and PE_PGRS43b while in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 1bp insertion causes a different frameshift but at same place, 3bp:GCC deletion in BCG Pasteur and BCG Mexico after 2409:G of Mycobacterium bovis, 1bp:T deletion in BCG Tokyo at 2931:T of Mycobacterium bovis.; PE-PGRS family protein 2749397 PE_PGRS43a 11810794 PE_PGRS43a Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005171958.1 2747970 R 717522 CDS YP_005171959.1 378772226 11810795 complement(2749484..2749675) 1 NC_016804.1 hypothetical protein 2749675 11810795 BCGMEX_2502c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171959.1 2749484 R 717522 CDS YP_005171960.1 378772227 11810796 2749826..2750449 1 NC_016804.1 hypothetical protein 2750449 11810796 BCGMEX_2503 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171960.1 2749826 D 717522 CDS YP_005171961.1 378772228 11810797 2750439..2751191 1 NC_016804.1 Differs from Rv2492 by 1aa, D70A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2751191 11810797 BCGMEX_2504 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171961.1 2750439 D 717522 CDS YP_005171962.1 378772229 11810798 2751244..2751465 1 NC_016804.1 hypothetical protein 2751465 11810798 BCGMEX_2505 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171962.1 2751244 D 717522 CDS YP_005171963.1 378772230 11810799 2751471..2751896 1 NC_016804.1 hypothetical protein 2751896 11810799 BCGMEX_2506 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171963.1 2751471 D 717522 CDS YP_005171964.1 378772231 11810800 complement(2751919..2753100) 1 NC_016804.1 Differs from Rv2495c by 2aa, A107T, W208R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; dihydrolipoamide acyltransferase E2 component 2753100 pdhC 11810800 pdhC Mycobacterium bovis BCG str. Mexico dihydrolipoamide acyltransferase E2 component YP_005171964.1 2751919 R 717522 CDS YP_005171965.1 378772232 11810801 complement(2753097..2754143) 1 NC_016804.1 Differs from Rv2496c by 1aa, S201G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative pyruvate dehydrogenase E1 component subunit beta 2754143 pdhB 11810801 pdhB Mycobacterium bovis BCG str. Mexico putative pyruvate dehydrogenase E1 component subunit beta YP_005171965.1 2753097 R 717522 CDS YP_005171966.1 378772233 11810802 complement(2754154..2755257) 1 NC_016804.1 Pyruvate dehydrogenase E1 component subunit alpha 2755257 pdhA 11810802 pdhA Mycobacterium bovis BCG str. Mexico Pyruvate dehydrogenase E1 component subunit alpha YP_005171966.1 2754154 R 717522 CDS YP_005171967.1 378772234 11810803 complement(2755516..2756337) 1 NC_016804.1 putative citrate (Pro-3s) 2756337 citE 11810803 citE Mycobacterium bovis BCG str. Mexico putative citrate (Pro-3s) YP_005171967.1 2755516 R 717522 CDS YP_005171968.1 378772235 11810804 complement(2756334..2756891) 1 NC_016804.1 putative oxidase regulatory-related protein 2756891 11810804 BCGMEX_2511c Mycobacterium bovis BCG str. Mexico putative oxidase regulatory-related protein YP_005171968.1 2756334 R 717522 CDS YP_005171969.1 378772236 11810805 complement(2756888..2758072) 1 NC_016804.1 putative acyl-CoA dehydrogenase 2758072 fadE19 11810805 fadE19 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005171969.1 2756888 R 717522 CDS YP_005171970.1 378772237 11810806 complement(2758077..2760041) 1 NC_016804.1 acetyl-/propionyl-coenzyme A carboxylase alpha chain 2760041 accA1 11810806 accA1 Mycobacterium bovis BCG str. Mexico acetyl-/propionyl-coenzyme A carboxylase alpha chain YP_005171970.1 2758077 R 717522 CDS YP_005171971.1 378772238 11810807 complement(2760046..2761635) 1 NC_016804.1 Differs from Rv2502c by 2aa, S77G, L343F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acetyl-/propionyl-coa carboxylase subunit beta 2761635 accD1 11810807 accD1 Mycobacterium bovis BCG str. Mexico putative acetyl-/propionyl-coa carboxylase subunit beta YP_005171971.1 2760046 R 717522 CDS YP_005171972.1 378772239 11810808 complement(2761632..2762288) 1 NC_016804.1 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit beta 2762288 scoB 11810808 scoB Mycobacterium bovis BCG str. Mexico Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit beta YP_005171972.1 2761632 R 717522 CDS YP_005171973.1 378772240 11810809 complement(2762285..2763031) 1 NC_016804.1 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit alpha 2763031 scoA 11810809 scoA Mycobacterium bovis BCG str. Mexico Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit alpha YP_005171973.1 2762285 R 717522 CDS YP_005171974.1 378772241 11810810 complement(2763114..2764757) 1 NC_016804.1 Differs from Rv2505c and Mb2533c by 1aa, A381T in BCG Pasteur, BCG Tokyo and BCG Mexico; Fatty-acid-CoA ligase 2764757 fadD35 11810810 fadD35 Mycobacterium bovis BCG str. Mexico Fatty-acid-CoA ligase YP_005171974.1 2763114 R 717522 CDS YP_005171975.1 378772242 11810811 2764873..2765520 1 NC_016804.1 TetR family transcriptional regulator 2765520 11810811 BCGMEX_2518 Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005171975.1 2764873 D 717522 CDS YP_005171976.1 378772243 11810812 2765599..2766420 1 NC_016804.1 hypothetical protein 2766420 11810812 BCGMEX_2519 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171976.1 2765599 D 717522 CDS YP_005171977.1 378772244 11810813 complement(2766417..2767754) 1 NC_016804.1 putative integral membrane leucine and alanine rich protein 2767754 11810813 BCGMEX_2520c Mycobacterium bovis BCG str. Mexico putative integral membrane leucine and alanine rich protein YP_005171977.1 2766417 R 717522 CDS YP_005171978.1 378772245 11810814 2767839..2768645 1 NC_016804.1 putative short-chain dehydrogenase/reductase 2768645 11810814 BCGMEX_2521 Mycobacterium bovis BCG str. Mexico putative short-chain dehydrogenase/reductase YP_005171978.1 2767839 D 717522 CDS YP_005171979.1 378772246 11810815 complement(2768649..2770250) 1 NC_016804.1 hypothetical protein 2770250 11810815 BCGMEX_2522c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171979.1 2768649 R 717522 CDS YP_005171980.1 378772247 11810816 2770318..2770965 1 NC_016804.1 oligoribonuclease 2770965 orn 11810816 orn Mycobacterium bovis BCG str. Mexico oligoribonuclease YP_005171980.1 2770318 D 717522 CDS YP_005171981.1 378772248 11810818 complement(2771717..2772964) 1 NC_016804.1 Transposase for insertion sequence element IS1081 2772964 11810818 BCGMEX_2524c Mycobacterium bovis BCG str. Mexico Transposase for insertion sequence element IS1081 YP_005171981.1 2771717 R 717522 CDS YP_005171982.1 378772249 11810819 2772964..2773101 1 NC_016804.1 hypothetical protein 2773101 11810819 BCGMEX_2525 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171982.1 2772964 D 717522 CDS YP_005171983.1 378772250 11810820 2773322..2773744 1 NC_016804.1 Differs from Rv2513 by 1aa, K122T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2773744 11810820 BCGMEX_2526 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171983.1 2773322 D 717522 CDS YP_005171984.1 378772251 11810821 complement(2774038..2774499) 1 NC_016804.1 hypothetical protein 2774499 11810821 BCGMEX_2527c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171984.1 2774038 R 717522 CDS YP_005171985.1 378772252 11810822 complement(2774505..2775752) 1 NC_016804.1 hypothetical protein 2775752 11810822 BCGMEX_2528c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171985.1 2774505 R 717522 CDS YP_005171986.1 378772253 11810823 complement(2775871..2776674) 1 NC_016804.1 hypothetical protein 2776674 11810823 BCGMEX_2529c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171986.1 2775871 R 717522 CDS YP_005171987.1 378772254 11810824 complement(2776671..2776922) 1 NC_016804.1 hypothetical protein 2776922 11810824 BCGMEX_2530c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171987.1 2776671 R 717522 CDS YP_005171988.1 378772255 11810825 complement(2777270..2778496) 1 NC_016804.1 putative lipoprotein 2778496 lppS 11810825 lppS Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005171988.1 2777270 R 717522 CDS YP_005171989.1 378772256 11810827 2778946..2780424 1 NC_016804.1 similar to Rv2519 but differs from Mb2548 by 1aa, G173A, due to 2bp substitution in BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 2780424 PE26 11810827 PE26 Mycobacterium bovis BCG str. Mexico PE family protein YP_005171989.1 2778946 D 717522 CDS YP_005171990.1 378772257 11810828 complement(2780549..2780776) 1 NC_016804.1 membrane protein 2780776 11810828 BCGMEX_2533c Mycobacterium bovis BCG str. Mexico membrane protein YP_005171990.1 2780549 R 717522 CDS YP_005171991.1 378772258 11810829 2780845..2781318 1 NC_016804.1 Differs from Mb2550 by 1aa, V122M in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative bacterioferritin comigratory protein 2781318 bcp 11810829 bcp Mycobacterium bovis BCG str. Mexico putative bacterioferritin comigratory protein YP_005171991.1 2780845 D 717522 CDS YP_005171992.1 378772259 11810830 complement(2781290..2782702) 1 NC_016804.1 hypothetical protein 2782702 11810830 BCGMEX_2535c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171992.1 2781290 R 717522 CDS YP_005171993.1 378772260 11810831 complement(2782699..2783091) 1 NC_016804.1 holo-[acyl-carrier protein] synthase 2783091 acpS 11810831 acpS Mycobacterium bovis BCG str. Mexico holo-[acyl-carrier protein] synthase YP_005171993.1 2782699 R 717522 CDS YP_005171994.1 378772261 11810832 complement(2783284..2792493) 1 NC_016804.1 putative fatty acid synthase 2792493 fas 11810832 fas Mycobacterium bovis BCG str. Mexico putative fatty acid synthase YP_005171994.1 2783284 R 717522 CDS YP_005171995.1 378772262 11810833 complement(2793013..2793735) 1 NC_016804.1 hypothetical protein 2793735 11810833 BCGMEX_2538c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171995.1 2793013 R 717522 CDS YP_005171996.1 378772263 11810834 2794252..2794479 1 NC_016804.1 hypothetical protein 2794479 11810834 BCGMEX_2539 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171996.1 2794252 D 717522 CDS YP_005171997.1 378772264 11810835 2794476..2794877 1 NC_016804.1 hypothetical protein 2794877 11810835 BCGMEX_2540 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171997.1 2794476 D 717522 CDS YP_005171998.1 378772265 11810836 complement(2794912..2795832) 1 NC_016804.1 Differs from Rv2528c by 1aa, L94P, and Mb2557c by 2aa, L94P, E259Q in BCG Pasteur, BCG Tokyo and BCG Mexico; putative restriction system protein 2795832 mrr 11810836 mrr Mycobacterium bovis BCG str. Mexico putative restriction system protein YP_005171998.1 2794912 R 717522 CDS YP_005171999.1 378772266 11810837 2796036..2797427 1 NC_016804.1 Differs from Mb2558 by 1aa, G94E in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2797427 11810837 BCGMEX_2542 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005171999.1 2796036 D 717522 CDS YP_005172000.1 378772267 11810838 complement(2797428..2797847) 1 NC_016804.1 hypothetical protein 2797847 11810838 BCGMEX_2543c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172000.1 2797428 R 717522 CDS YP_005172001.1 378772268 11810839 complement(2797844..2798068) 1 NC_016804.1 hypothetical protein 2798068 11810839 BCGMEX_2544c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172001.1 2797844 R 717522 CDS YP_005172002.1 378772269 11810840 complement(2798099..2800942) 1 NC_016804.1 putative amino acid decarboxylase 2800942 11810840 BCGMEX_2545c Mycobacterium bovis BCG str. Mexico putative amino acid decarboxylase YP_005172002.1 2798099 R 717522 CDS YP_005172003.1 378772270 11810841 complement(2801014..2801415) 1 NC_016804.1 hypothetical protein 2801415 11810841 BCGMEX_2546c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172003.1 2801014 R 717522 CDS YP_005172004.1 378772271 11810842 complement(2801415..2801885) 1 NC_016804.1 Differs from Rv2533c by 1aa, D19A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; N utilization substance protein B-like protein 2801885 nusB 11810842 nusB Mycobacterium bovis BCG str. Mexico N utilization substance protein B-like protein YP_005172004.1 2801415 R 717522 CDS YP_005172005.1 378772272 11810843 complement(2801888..2802451) 1 NC_016804.1 elongation factor P 2802451 efp 11810843 efp Mycobacterium bovis BCG str. Mexico elongation factor P YP_005172005.1 2801888 R 717522 CDS YP_005172006.1 378772273 11810844 complement(2802461..2803579) 1 NC_016804.1 putative cytoplasmic peptidase 2803579 pepQ 11810844 pepQ Mycobacterium bovis BCG str. Mexico putative cytoplasmic peptidase YP_005172006.1 2802461 R 717522 CDS YP_005172007.1 378772274 11810845 2803613..2804305 1 NC_016804.1 putative transmembrane protein 2804305 11810845 BCGMEX_2550 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172007.1 2803613 D 717522 CDS YP_005172008.1 378772275 11810846 complement(2804309..2804752) 1 NC_016804.1 3-dehydroquinate dehydratase 2804752 aroD 11810846 aroD Mycobacterium bovis BCG str. Mexico 3-dehydroquinate dehydratase YP_005172008.1 2804309 R 717522 CDS YP_005172009.1 378772276 11810847 complement(2804749..2805837) 1 NC_016804.1 3-dehydroquinate synthase 2805837 aroB 11810847 aroB Mycobacterium bovis BCG str. Mexico 3-dehydroquinate synthase YP_005172009.1 2804749 R 717522 CDS YP_005172010.1 378772277 11810848 complement(2805834..2806364) 1 NC_016804.1 shikimate kinase 2806364 aroK 11810848 aroK Mycobacterium bovis BCG str. Mexico shikimate kinase YP_005172010.1 2805834 R 717522 CDS YP_005172011.1 378772278 11810849 complement(2806368..2807573) 1 NC_016804.1 chorismate synthase 2807573 aroF 11810849 aroF Mycobacterium bovis BCG str. Mexico chorismate synthase YP_005172011.1 2806368 R 717522 CDS YP_005172012.1 378772279 11810850 2807588..2807995 1 NC_016804.1 hypothetical protein 2807995 11810850 BCGMEX_2555 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172012.1 2807588 D 717522 CDS YP_005172013.1 378772280 11810851 2808291..2809502 1 NC_016804.1 Differs from Rv2542 by 1aa, A211T in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2809502 11810851 BCGMEX_2556 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172013.1 2808291 D 717522 CDS YP_005172014.1 378772281 11810852 2809629..2810288 1 NC_016804.1 putative lipoprotein 2810288 lppA 11810852 lppA Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172014.1 2809629 D 717522 CDS YP_005172015.1 378772282 11810853 2810285..2810944 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovisBCG Pasteur, BCG Tokyo and BCG Mexico, there is a 656 bp insertion, relative to Mycobacterium tuberculosis strain H37Rv, which leads to lppR gene, probably by duplication of llpA or lppB; putative lipoprotein 2810944 lprR 11810853 lprR Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172015.1 2810285 D 717522 CDS YP_005172016.1 378772283 11810854 2810941..2811603 1 NC_016804.1 putative lipoprotein 2811603 lppB 11810854 lppB Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172016.1 2810941 D 717522 CDS YP_005172017.1 378772284 11810855 2811600..2811878 1 NC_016804.1 hypothetical protein 2811878 11810855 BCGMEX_2560 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172017.1 2811600 D 717522 CDS YP_005172018.1 378772285 11810856 2811971..2812384 1 NC_016804.1 hypothetical protein 2812384 11810856 BCGMEX_2561 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172018.1 2811971 D 717522 CDS YP_005172019.1 378772286 11810857 2812423..2812680 1 NC_016804.1 DNA-binding protein, CopG family 2812680 11810857 BCGMEX_2562 Mycobacterium bovis BCG str. Mexico DNA-binding protein, CopG family YP_005172019.1 2812423 D 717522 CDS YP_005172020.1 378772287 11810858 2812677..2813054 1 NC_016804.1 hypothetical protein 2813054 11810858 BCGMEX_2563 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172020.1 2812677 D 717522 CDS YP_005172021.1 378772288 11810859 complement(2813070..2813444) 1 NC_016804.1 hypothetical protein 2813444 11810859 BCGMEX_2564c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172021.1 2813070 R 717522 CDS YP_005172022.1 378772289 11810860 complement(2813544..2813939) 1 NC_016804.1 hypothetical protein 2813939 11810860 BCGMEX_2565c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172022.1 2813544 R 717522 CDS YP_005172023.1 378772290 11810861 complement(2813936..2814181) 1 NC_016804.1 putative DNA-binding protein, CopG family 2814181 11810861 BCGMEX_2566c Mycobacterium bovis BCG str. Mexico putative DNA-binding protein, CopG family YP_005172023.1 2813936 R 717522 CDS YP_005172024.1 378772291 11810862 complement(2814592..2815011) 1 NC_016804.1 hypothetical protein 2815011 11810862 BCGMEX_2567c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172024.1 2814592 R 717522 CDS YP_005172025.1 378772292 11810863 complement(2815023..2815805) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base deletion leads to a shorter product compared to Mycobacterium tuberculosis strain H37Rv (260 aa versus 269 aa); shikimate 5-dehydrogenase 2815805 aroE 11810863 aroE Mycobacterium bovis BCG str. Mexico shikimate 5-dehydrogenase YP_005172025.1 2815023 R 717522 CDS YP_005172026.1 378772293 11810864 complement(2815828..2817081) 1 NC_016804.1 hypothetical protein 2817081 11810864 BCGMEX_2569c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172026.1 2815828 R 717522 CDS YP_005172027.1 378772294 11810865 complement(2817074..2817586) 1 NC_016804.1 putative Holliday junction resolvase 2817586 11810865 BCGMEX_2570c Mycobacterium bovis BCG str. Mexico putative Holliday junction resolvase YP_005172027.1 2817074 R 717522 CDS YP_005172028.1 378772295 11810866 complement(2817587..2820301) 1 NC_016804.1 Differs from Rv2555c by 1aa, N226K in Mycobacterium bovis BCG Pasteur, BCG Tokio and BCG Mexico; alanyl-tRNA synthetase 2820301 alaS 11810866 alaS Mycobacterium bovis BCG str. Mexico alanyl-tRNA synthetase YP_005172028.1 2817587 R 717522 CDS YP_005172029.1 378772296 11810867 complement(2820392..2820781) 1 NC_016804.1 hypothetical protein 2820781 11810867 BCGMEX_2572c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172029.1 2820392 R 717522 CDS YP_005172030.1 378772297 11810868 2820888..2821562 1 NC_016804.1 hypothetical protein 2821562 11810868 BCGMEX_2573 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172030.1 2820888 D 717522 CDS YP_005172031.1 378772298 11810869 2821647..2822357 1 NC_016804.1 hypothetical protein 2822357 11810869 BCGMEX_2574 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172031.1 2821647 D 717522 CDS YP_005172032.1 378772299 11810870 complement(2822387..2823745) 1 NC_016804.1 Differs from Rv2559c by 1aa, D317G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2823745 11810870 BCGMEX_2575c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172032.1 2822387 R 717522 CDS YP_005172033.1 378772300 11810871 2823891..2824868 1 NC_016804.1 Differs from Rv2560 by 1aa, L210V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; proline and glycine rich transmembrane protein 2824868 11810871 BCGMEX_2576 Mycobacterium bovis BCG str. Mexico proline and glycine rich transmembrane protein YP_005172033.1 2823891 D 717522 CDS YP_005172034.1 378772301 11810872 2825225..2825962 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2561 and Rv2562 exist as 2 genes. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base deletion results in a single product which is more similar to Rv2561; hypothetical protein 2825962 11810872 BCGMEX_2577 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172034.1 2825225 D 717522 CDS YP_005172035.1 378772302 11810873 2826105..2827154 1 NC_016804.1 putative glutamine-transport transmembrane protein ABC transporter 2827154 11810873 BCGMEX_2578 Mycobacterium bovis BCG str. Mexico putative glutamine-transport transmembrane protein ABC transporter YP_005172035.1 2826105 D 717522 CDS YP_005172036.1 378772303 11810874 2827157..2828149 1 NC_016804.1 putative glutamine-transport ATP-binding protein ABC transporter 2828149 glnQ 11810874 glnQ Mycobacterium bovis BCG str. Mexico putative glutamine-transport ATP-binding protein ABC transporter YP_005172036.1 2827157 D 717522 CDS YP_005172037.1 378772304 11810875 2828426..2830177 1 NC_016804.1 hypothetical protein 2830177 11810875 BCGMEX_2580 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172037.1 2828426 D 717522 CDS YP_005172038.1 378772305 11810876 2830188..2831789 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2566 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 2bp deletion splits Rv2566 into 2 parts. Differs from first part of Rv2566 by 3aa, S10G, S270A, L315V and from Mb2595 by 1aa, L315V in BCG Pasteur, BCG Tokyo and BCG Mexico; Large protein containing transglutaminase-like domain 2831789 11810876 BCGMEX_2581 Mycobacterium bovis BCG str. Mexico Large protein containing transglutaminase-like domain YP_005172038.1 2830188 D 717522 CDS YP_005172039.1 378772306 11810877 2831815..2833608 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2566 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 2bp deletion splits Rv2566 into 2 parts. Differs from Rv2566 by 2aa, P67L, E326G, and from Mb2596 by 1aa, E326G in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2833608 11810877 BCGMEX_2582 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172039.1 2831815 D 717522 CDS YP_005172040.1 378772307 11810878 2833608..2836262 1 NC_016804.1 Differs from Rv2567 by 1aa, R645Q in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2836262 11810878 BCGMEX_2583 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172040.1 2833608 D 717522 CDS YP_005172041.1 378772308 11810879 complement(2836259..2837284) 1 NC_016804.1 hypothetical protein 2837284 11810879 BCGMEX_2584c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172041.1 2836259 R 717522 CDS YP_005172042.1 378772309 11810880 complement(2837277..2838221) 1 NC_016804.1 hypothetical protein 2838221 11810880 BCGMEX_2585c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172042.1 2837277 R 717522 CDS YP_005172043.1 378772310 11810881 2838325..2838714 1 NC_016804.1 hypothetical protein 2838714 11810881 BCGMEX_2586 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172043.1 2838325 D 717522 CDS YP_005172044.1 378772311 11810882 complement(2838706..2839773) 1 NC_016804.1 Differs from Rv2571c and Mb2601c by 1aa, C68R in Mycobacterium bovis BCG Pasteur; putative transmembrane alanine and valine and leucine rich protein 2839773 11810882 BCGMEX_2587c Mycobacterium bovis BCG str. Mexico putative transmembrane alanine and valine and leucine rich protein YP_005172044.1 2838706 R 717522 CDS YP_005172045.1 378772312 11810883 complement(2839780..2841615) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico and Mycobacterium bovis, a single base deletion omitting a stop codon, leads to a longer protein with a different COOH end compared to its homolog in Mycobacterium tuberculosis strain H37Rv (611 aa versus 596 aa). Differs from Rv2572c by 1aa, V515A in in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; aspartyl-tRNA synthetase 2841615 aspS 11810883 aspS Mycobacterium bovis BCG str. Mexico aspartyl-tRNA synthetase YP_005172045.1 2839780 R 717522 CDS YP_005172046.1 378772313 11810884 2841855..2842595 1 NC_016804.1 2-dehydropantoate 2-reductase 2842595 11810884 BCGMEX_2589 Mycobacterium bovis BCG str. Mexico 2-dehydropantoate 2-reductase YP_005172046.1 2841855 D 717522 CDS YP_005172047.1 378772314 11810885 2842618..2843121 1 NC_016804.1 hypothetical protein 2843121 11810885 BCGMEX_2590 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172047.1 2842618 D 717522 CDS YP_005172048.1 378772315 11810886 2843151..2844032 1 NC_016804.1 putative membrane glycine rich protein 2844032 11810886 BCGMEX_2591 Mycobacterium bovis BCG str. Mexico putative membrane glycine rich protein YP_005172048.1 2843151 D 717522 CDS YP_005172049.1 378772316 11810887 complement(2844038..2844502) 1 NC_016804.1 hypothetical protein 2844502 11810887 BCGMEX_2592c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172049.1 2844038 R 717522 CDS YP_005172050.1 378772317 11810888 2844730..2846319 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, Rv2577 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base transition splits Rv2577 into 2 parts, Mb2607 and Mb2608; hypothetical protein 2846319 11810888 BCGMEX_2593 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172050.1 2844730 D 717522 CDS YP_005172051.1 378772318 11810889 complement(2846321..2847343) 1 NC_016804.1 hypothetical protein 2847343 11810889 BCGMEX_2594c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172051.1 2846321 R 717522 CDS YP_005172052.1 378772319 11810890 2847451..2848353 1 NC_016804.1 Differs from Rv2579 by 1aa, Q293T, and from Mb2610by 1aa, A96T in BCG Pasteur, BCG Tokyo and BCG Mexico; haloalkane dehalogenase 2848353 dhaA 11810890 dhaA Mycobacterium bovis BCG str. Mexico haloalkane dehalogenase YP_005172052.1 2847451 D 717522 CDS YP_005172053.1 378772320 11810891 complement(2848633..2849904) 1 NC_016804.1 histidyl-tRNA synthetase 2849904 hisS 11810891 hisS Mycobacterium bovis BCG str. Mexico histidyl-tRNA synthetase YP_005172053.1 2848633 R 717522 CDS YP_005172054.1 378772321 11810892 complement(2849901..2850575) 1 NC_016804.1 putative glyoxalase II 2850575 11810892 BCGMEX_2597c Mycobacterium bovis BCG str. Mexico putative glyoxalase II YP_005172054.1 2849901 R 717522 CDS YP_005172055.1 378772322 11810893 2850626..2851552 1 NC_016804.1 Differs from Rv2582 by 1aa, F66V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; peptidyl-prolyl cis-trans isomerase B 2851552 11810893 BCGMEX_2598 Mycobacterium bovis BCG str. Mexico peptidyl-prolyl cis-trans isomerase B YP_005172055.1 2850626 D 717522 CDS YP_005172056.1 378772323 11810894 complement(2851638..2854010) 1 NC_016804.1 putative GTP pyrophosphokinase 2854010 relA 11810894 relA Mycobacterium bovis BCG str. Mexico putative GTP pyrophosphokinase YP_005172056.1 2851638 R 717522 CDS YP_005172057.1 378772324 11810895 complement(2854041..2854712) 1 NC_016804.1 Differs from Rv2584c by 1aa, E147A in Mycobacterium tuberculosis CCDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Adenine phosphoribosyltransferase 2854712 apt 11810895 apt Mycobacterium bovis BCG str. Mexico Adenine phosphoribosyltransferase YP_005172057.1 2854041 R 717522 CDS YP_005172058.1 378772325 11810896 complement(2854816..2856489) 1 NC_016804.1 Differs from Rv2585c by 1aa, S462C in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 2856489 11810896 BCGMEX_2601c Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172058.1 2854816 R 717522 CDS YP_005172059.1 378772326 11810897 complement(2856495..2857823) 1 NC_016804.1 Differs from Rv2586c by 2aa, T309A, P434T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; protein-export membrane protein 2857823 secF 11810897 secF Mycobacterium bovis BCG str. Mexico protein-export membrane protein YP_005172059.1 2856495 R 717522 CDS YP_005172060.1 378772327 11810898 complement(2857827..2859548) 1 NC_016804.1 Differs from Mb2618c by 1aa, N493S in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; protein-export membrane protein SecD 2859548 secD 11810898 secD Mycobacterium bovis BCG str. Mexico protein-export membrane protein SecD YP_005172060.1 2857827 R 717522 CDS YP_005172061.1 378772328 11810899 complement(2859658..2860005) 1 NC_016804.1 preprotein translocase subunit 2860005 yajC 11810899 yajC Mycobacterium bovis BCG str. Mexico preprotein translocase subunit YP_005172061.1 2859658 R 717522 CDS YP_005172062.1 378772329 11810900 2860172..2861521 1 NC_016804.1 4-aminobutyrate aminotransferase 2861521 gabT 11810900 gabT Mycobacterium bovis BCG str. Mexico 4-aminobutyrate aminotransferase YP_005172062.1 2860172 D 717522 CDS YP_005172063.1 378772330 11810901 2861683..2865189 1 NC_016804.1 Differs from Rv2590 by 1aa, Y309F, and from Mb2621 by 1aa, A1106T in BCG Pasteur, BCG Tokyo and BCG Mexico; long-chain-fatty-acid--CoA ligase 2865189 fadD9 11810901 fadD9 Mycobacterium bovis BCG str. Mexico long-chain-fatty-acid--CoA ligase YP_005172063.1 2861683 D 717522 CDS YP_005172064.1 378772331 11810902 2865363..2867003 1 NC_016804.1 Differs from Rv2591 by extra 3 aa resulting from same 9 bp in-frame insertion as in Mycobacterium bovis and by 2aa S415G, D463G in BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 2867003 PE_PGRS44 11810902 PE_PGRS44 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005172064.1 2865363 D 717522 CDS YP_005172065.1 378772332 11810903 complement(2867020..2868054) 1 NC_016804.1 holliday junction DNA helicase B 2868054 ruvB 11810903 ruvB Mycobacterium bovis BCG str. Mexico holliday junction DNA helicase B YP_005172065.1 2867020 R 717522 CDS YP_005172066.1 378772333 11810904 complement(2868051..2868641) 1 NC_016804.1 holliday junction DNA helicase motor protein 2868641 ruvA 11810904 ruvA Mycobacterium bovis BCG str. Mexico holliday junction DNA helicase motor protein YP_005172066.1 2868051 R 717522 CDS YP_005172067.1 378772334 11810905 complement(2868638..2869204) 1 NC_016804.1 Crossover junction endodeoxyribonuclease ruvC 2869204 ruvC 11810905 ruvC Mycobacterium bovis BCG str. Mexico Crossover junction endodeoxyribonuclease ruvC YP_005172067.1 2868638 R 717522 CDS YP_005172068.1 378772335 11810906 2869313..2869558 1 NC_016804.1 hypothetical protein 2869558 11810906 BCGMEX_2611 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172068.1 2869313 D 717522 CDS YP_005172069.1 378772336 11810907 2869555..2869959 1 NC_016804.1 Differs from Rv2596 by 1aa, R77C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2869959 11810907 BCGMEX_2612 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172069.1 2869555 D 717522 CDS YP_005172070.1 378772337 11810908 2870176..2870796 1 NC_016804.1 hypothetical protein 2870796 11810908 BCGMEX_2613 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172070.1 2870176 D 717522 CDS YP_005172071.1 378772338 11810909 2870807..2871301 1 NC_016804.1 hypothetical protein 2871301 11810909 BCGMEX_2614 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172071.1 2870807 D 717522 CDS YP_005172072.1 378772339 11810910 2871298..2871729 1 NC_016804.1 Differs from Rv2599 by 1aa, I12S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2871729 11810910 BCGMEX_2615 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172072.1 2871298 D 717522 CDS YP_005172073.1 378772340 11810911 2871811..2872017 1 NC_016804.1 First 64 aa similar to N-terminal part of Rv2600 and Mb2631 but then frameshifts due to 10bp deletion. Results in BCG Pasteur, BCG Tokyo and BCG Mexico orthologs of Mb2631 and Rv2600 being in two parts; putative integral membrane protein 2872017 11810911 BCGMEX_2616 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172073.1 2871811 D 717522 CDS YP_005172074.1 378772341 11810912 2872023..2872202 1 NC_016804.1 All 59aa are similar to C-terminal part of Rv2600 and Mb2631 owing to frameshifts due to 10bp deletion. Results in BCG Pasteur, BCG Tokyo and BCG Mexico orthologs of Mb2631 and Rv2600 being in two parts, both of which encode hydrophobic proteins; putative integral membrane protein 2872202 11810912 BCGMEX_2617 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172074.1 2872023 D 717522 CDS YP_005172075.1 378772342 11810913 2872199..2873770 1 NC_016804.1 spermidine synthase 2873770 speE 11810913 speE Mycobacterium bovis BCG str. Mexico spermidine synthase YP_005172075.1 2872199 D 717522 CDS YP_005172076.1 378772343 11810914 2873881..2874168 1 NC_016804.1 hypothetical protein 2874168 11810914 BCGMEX_2619 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172076.1 2873881 D 717522 CDS YP_005172077.1 378772344 11810915 2874155..2874595 1 NC_016804.1 hypothetical protein 2874595 11810915 BCGMEX_2620 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172077.1 2874155 D 717522 CDS YP_005172078.1 378772345 11810916 complement(2874616..2875371) 1 NC_016804.1 hypothetical protein 2875371 11810916 BCGMEX_2621c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172078.1 2874616 R 717522 CDS YP_005172079.1 378772346 11810917 complement(2875504..2876100) 1 NC_016804.1 glutamine amidotransferase subunit pdxT 2876100 pdxT 11810917 pdxT Mycobacterium bovis BCG str. Mexico glutamine amidotransferase subunit pdxT YP_005172079.1 2875504 R 717522 CDS YP_005172080.1 378772347 11810918 complement(2876108..2876953) 1 NC_016804.1 Differs from Rv2605c by 1aa, L85F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyl-CoA thioesterase II 2876953 tesB2 11810918 tesB2 Mycobacterium bovis BCG str. Mexico putative acyl-CoA thioesterase II YP_005172080.1 2876108 R 717522 CDS YP_005172081.1 378772348 11810919 complement(2876982..2877881) 1 NC_016804.1 pyridoxal biosynthesis lyase pdxS 2877881 pdxS 11810919 pdxS Mycobacterium bovis BCG str. Mexico pyridoxal biosynthesis lyase pdxS YP_005172081.1 2876982 R 717522 CDS YP_005172082.1 378772349 11810920 2878009..2878683 1 NC_016804.1 Pyridoxamine 5'-phosphate oxidase 2878683 pdxH 11810920 pdxH Mycobacterium bovis BCG str. Mexico Pyridoxamine 5'-phosphate oxidase YP_005172082.1 2878009 D 717522 CDS YP_005172083.1 378772350 11810921 2878857..2880599 1 NC_016804.1 Differs from Rv2608 by 1aa, S281P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 2880599 PPE42 11810921 PPE42 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172083.1 2878857 D 717522 CDS YP_005172084.1 378772351 11810922 complement(2880621..2881676) 1 NC_016804.1 membrane protein 2881676 11810922 BCGMEX_2627c Mycobacterium bovis BCG str. Mexico membrane protein YP_005172084.1 2880621 R 717522 CDS YP_005172085.1 378772352 11810923 complement(2881676..2882812) 1 NC_016804.1 alpha-mannosyltransferase 2882812 pimA 11810923 pimA Mycobacterium bovis BCG str. Mexico alpha-mannosyltransferase YP_005172085.1 2881676 R 717522 CDS YP_005172086.1 378772353 11810924 complement(2882823..2883773) 1 NC_016804.1 Differs from Rv2611c by 2aa, M102I, C197S in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Lipid A biosynthesis lauroyl acyltransferase 2883773 11810924 BCGMEX_2629c Mycobacterium bovis BCG str. Mexico Lipid A biosynthesis lauroyl acyltransferase YP_005172086.1 2882823 R 717522 CDS YP_005172087.1 378772354 11810925 complement(2883770..2884423) 1 NC_016804.1 CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2884423 pgsA1 11810925 pgsA1 Mycobacterium bovis BCG str. Mexico CDP-diacylglycerol--inositol 3-phosphatidyltransferase YP_005172087.1 2883770 R 717522 CDS YP_005172088.1 378772355 11810926 complement(2884420..2885007) 1 NC_016804.1 hypothetical protein 2885007 11810926 BCGMEX_2631c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172088.1 2884420 R 717522 CDS YP_005172089.1 378772356 11810927 complement(2885000..2887078) 1 NC_016804.1 Threonyl-tRNA synthetase 2887078 thrS 11810927 thrS Mycobacterium bovis BCG str. Mexico Threonyl-tRNA synthetase YP_005172089.1 2885000 R 717522 CDS YP_005172090.1 378772357 11810928 complement(2887411..2888580) 1 NC_016804.1 In Mycobacterium bovis, a 9 bp in-frame insertion leads to a slightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (464 aa versus 461 aa). In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 7bp deletion splits PE_PGRS45 in two parts; PE-PGRS family protein 2888580 PE_PGRS45b 11810928 PE_PGRS45b Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005172090.1 2887411 R 717522 CDS YP_005172091.1 378772358 11810929 complement(2888568..2888798) 1 NC_016804.1 In Mycobacterium bovis, a 9 bp in-frame insertion leads to a slightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (464 aa versus 461 aa). In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 7bp deletion splits PE_PGRS45 in two parts. Differs from Rv2615c by 1aa, V40A in BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 2888798 PE_PGRS45a 11810929 PE_PGRS45a Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005172091.1 2888568 R 717522 CDS YP_005172092.1 378772359 11810930 2889143..2889643 1 NC_016804.1 Differs from Rv2616 by 1aa, I72V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2889643 11810930 BCGMEX_2635 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172092.1 2889143 D 717522 CDS YP_005172093.1 378772360 11810931 complement(2889660..2890100) 1 NC_016804.1 putative transmembrane protein 2890100 11810931 BCGMEX_2636c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172093.1 2889660 R 717522 CDS YP_005172094.1 378772361 11810932 2890247..2890924 1 NC_016804.1 hypothetical protein 2890924 11810932 BCGMEX_2637 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172094.1 2890247 D 717522 CDS YP_005172095.1 378772362 11810933 complement(2890909..2891262) 1 NC_016804.1 hypothetical protein 2891262 11810933 BCGMEX_2638c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172095.1 2890909 R 717522 CDS YP_005172096.1 378772363 11810934 complement(2891275..2891700) 1 NC_016804.1 putative transmembrane protein 2891700 11810934 BCGMEX_2639c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172096.1 2891275 R 717522 CDS YP_005172097.1 378772364 11810935 complement(2891697..2892368) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 3 bp deletion leads to a slightly shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (223 aa versus 224 aa) due to deletion of 1aa after position 194; putative transcriptional regulatory protein 2892368 11810935 BCGMEX_2640c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172097.1 2891697 R 717522 CDS YP_005172098.1 378772365 11810936 2892446..2893267 1 NC_016804.1 putative methyltransferase 2893267 11810936 BCGMEX_2641 Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005172098.1 2892446 D 717522 CDS YP_005172099.1 378772366 11810937 2893403..2894296 1 NC_016804.1 Universal stress protein family 2894296 11810937 BCGMEX_2642 Mycobacterium bovis BCG str. Mexico Universal stress protein family YP_005172099.1 2893403 D 717522 CDS YP_005172100.1 378772367 11810938 complement(2894299..2895117) 1 NC_016804.1 Universal stress protein family 2895117 11810938 BCGMEX_2643c Mycobacterium bovis BCG str. Mexico Universal stress protein family YP_005172100.1 2894299 R 717522 CDS YP_005172101.1 378772368 11810939 complement(2895132..2896313) 1 NC_016804.1 putative transmembrane alanine and leucine rich protein 2896313 11810939 BCGMEX_2644c Mycobacterium bovis BCG str. Mexico putative transmembrane alanine and leucine rich protein YP_005172101.1 2895132 R 717522 CDS YP_005172102.1 378772369 11810940 complement(2896372..2896803) 1 NC_016804.1 hypoxic response protein 1 2896803 11810940 BCGMEX_2645c Mycobacterium bovis BCG str. Mexico hypoxic response protein 1 YP_005172102.1 2896372 R 717522 CDS YP_005172103.1 378772370 11810941 complement(2897317..2898558) 1 NC_016804.1 Differs from Rv2627c by 1aa, G104R in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2898558 11810941 BCGMEX_2646c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172103.1 2897317 R 717522 CDS YP_005172104.1 378772371 11810942 2898868..2899230 1 NC_016804.1 Differs from Rv2628 by 1aa, L59S, and from Mb2661 by 1aa, P68R in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2899230 11810942 BCGMEX_2647 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172104.1 2898868 D 717522 CDS YP_005172105.1 378772372 11810943 2899577..2900701 1 NC_016804.1 hypothetical protein 2900701 11810943 BCGMEX_2648 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172105.1 2899577 D 717522 CDS YP_005172106.1 378772373 11810944 2900703..2901242 1 NC_016804.1 hypothetical protein 2901242 11810944 BCGMEX_2649 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172106.1 2900703 D 717522 CDS YP_005172107.1 378772374 11810945 2901381..2902679 1 NC_016804.1 hypothetical protein 2902679 11810945 BCGMEX_2650 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172107.1 2901381 D 717522 CDS YP_005172108.1 378772375 11810946 complement(2902718..2902999) 1 NC_016804.1 hypothetical protein 2902999 11810946 BCGMEX_2651c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172108.1 2902718 R 717522 CDS YP_005172109.1 378772376 11810947 complement(2903144..2903629) 1 NC_016804.1 hypothetical protein 2903629 11810947 BCGMEX_2652c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172109.1 2903144 R 717522 CDS YP_005172110.1 378772377 11810948 complement(2903656..2903910) 1 NC_016804.1 hypothetical protein 2903910 11810948 BCGMEX_2653c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172110.1 2903656 R 717522 CDS YP_005172111.1 378772378 11810949 complement(2903914..2906316) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur,BCG Tokio and BCG Mexico an in-frame insertion of 66 bp, leads to a longer product compared to Mycobacterium bovis and Mycobacterium tuberculosis strain H37Rv (800 aa versus 778 aa); PE-PGRS family protein 2906316 PE_PGRS46 11810949 PE_PGRS46 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005172111.1 2903914 R 717522 CDS YP_005172112.1 378772379 11810950 2906345..2906587 1 NC_016804.1 hypothetical protein 2906587 11810950 BCGMEX_2655 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172112.1 2906345 D 717522 CDS YP_005172113.1 378772380 11810951 2906588..2907265 1 NC_016804.1 putative O-phosphotransferase 2907265 11810951 BCGMEX_2656 Mycobacterium bovis BCG str. Mexico putative O-phosphotransferase YP_005172113.1 2906588 D 717522 CDS YP_005172114.1 378772381 11810952 2907461..2908117 1 NC_016804.1 putative transmembrane protein 2908117 dedA 11810952 dedA Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172114.1 2907461 D 717522 CDS YP_005172115.1 378772382 11810953 2908280..2908726 1 NC_016804.1 anti-sigma factor antagonist 2908726 11810953 BCGMEX_2658 Mycobacterium bovis BCG str. Mexico anti-sigma factor antagonist YP_005172115.1 2908280 D 717522 CDS YP_005172116.1 378772383 11810954 complement(2908901..2909233) 1 NC_016804.1 hypothetical protein 2909233 11810954 BCGMEX_2659c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172116.1 2908901 R 717522 CDS YP_005172117.1 378772384 11810955 complement(2909353..2909712) 1 NC_016804.1 ArsR family transcriptional regulator 2909712 11810955 BCGMEX_2660c Mycobacterium bovis BCG str. Mexico ArsR family transcriptional regulator YP_005172117.1 2909353 R 717522 CDS YP_005172118.1 378772385 11810956 2909814..2910272 1 NC_016804.1 cadmium-induced protein 2910272 cadI 11810956 cadI Mycobacterium bovis BCG str. Mexico cadmium-induced protein YP_005172118.1 2909814 D 717522 CDS YP_005172119.1 378772386 11810957 2910408..2910788 1 NC_016804.1 putative transcriptional regulatory protein,ArsR-family 2910788 11810957 BCGMEX_2662 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein,ArsR-family YP_005172119.1 2910408 D 717522 CDS YP_005172120.1 378772387 11810958 2910785..2912281 1 NC_016804.1 Differs from Rv2643 by 1 aa A455V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative arsenic-transport integral membrane protein 2912281 arsC 11810958 arsC Mycobacterium bovis BCG str. Mexico putative arsenic-transport integral membrane protein YP_005172120.1 2910785 D 717522 CDS YP_005172121.1 378772388 11810959 complement(2912408..2912725) 1 NC_016804.1 hypothetical protein 2912725 11810959 BCGMEX_2664c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172121.1 2912408 R 717522 CDS YP_005172122.1 378772389 11810964 complement(2913862..2914083) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a large 10982 bp deletion (RD11 region) leads to deletion of genes between Rv2645 and Rv2659c compared to Mycobacterium tuberculosis strain H37Rv; hypothetical protein 2914083 11810964 BCGMEX_2665c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172122.1 2913862 R 717522 CDS YP_005172123.1 378772390 11810965 complement(2914080..2914469) 1 NC_016804.1 hypothetical protein 2914469 11810965 BCGMEX_2666c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172123.1 2914080 R 717522 CDS YP_005172124.1 378772391 11810966 2914375..2914647 1 NC_016804.1 hypothetical protein 2914647 11810966 BCGMEX_2667 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172124.1 2914375 D 717522 CDS YP_005172125.1 378772392 11810967 2914746..2914979 1 NC_016804.1 hypothetical protein 2914979 11810967 BCGMEX_2668 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172125.1 2914746 D 717522 CDS YP_005172126.1 378772393 11810968 2914990..2915244 1 NC_016804.1 hypothetical protein 2915244 11810968 BCGMEX_2669 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172126.1 2914990 D 717522 CDS YP_005172127.1 378772394 11810969 complement(2915473..2915964) 1 NC_016804.1 hypothetical protein 2915964 11810969 BCGMEX_2670c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172127.1 2915473 R 717522 CDS YP_005172128.1 378772395 11810970 2915592..2915873 1 NC_016804.1 putative arginine rich protein 2915873 11810970 BCGMEX_2671 Mycobacterium bovis BCG str. Mexico putative arginine rich protein YP_005172128.1 2915592 D 717522 CDS YP_005172129.1 378772396 11810971 2915964..2916767 1 NC_016804.1 putative transposase for insertion sequence element IS1081 2916767 11810971 BCGMEX_2672 Mycobacterium bovis BCG str. Mexico putative transposase for insertion sequence element IS1081 YP_005172129.1 2915964 D 717522 CDS YP_005172130.1 378772397 11810972 2916789..2917547 1 NC_016804.1 putative ATP-dependent protease ATP-binding subunit 2917547 clpX' 11810972 clpX' Mycobacterium bovis BCG str. Mexico putative ATP-dependent protease ATP-binding subunit YP_005172130.1 2916789 D 717522 CDS YP_005172131.1 378772398 11810973 2917626..2918147 1 NC_016804.1 Differs from Rv2668 by 2aa R3H and K162E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative exported alanine and valine rich protein 2918147 11810973 BCGMEX_2674 Mycobacterium bovis BCG str. Mexico putative exported alanine and valine rich protein YP_005172131.1 2917626 D 717522 CDS YP_005172132.1 378772399 11810974 2918176..2918646 1 NC_016804.1 hypothetical protein 2918646 11810974 BCGMEX_2675 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172132.1 2918176 D 717522 CDS YP_005172133.1 378772400 11810975 complement(2918624..2919733) 1 NC_016804.1 hypothetical protein 2919733 11810975 BCGMEX_2676c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172133.1 2918624 R 717522 CDS YP_005172134.1 378772401 11810976 2919732..2920508 1 NC_016804.1 putative bifunctional enzyme riboflavin biosynthesis protein ribD: diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase 2920508 ribD 11810976 ribD Mycobacterium bovis BCG str. Mexico putative bifunctional enzyme riboflavin biosynthesis protein ribD: diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase YP_005172134.1 2919732 D 717522 CDS YP_005172135.1 378772402 11810977 2920575..2922161 1 NC_016804.1 Differs from Rv2672 by 1aa D317H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative secreted protease 2922161 11810977 BCGMEX_2678 Mycobacterium bovis BCG str. Mexico putative secreted protease YP_005172135.1 2920575 D 717522 CDS YP_005172136.1 378772403 11810978 2922184..2923485 1 NC_016804.1 putative transmembrane protein 2923485 11810978 BCGMEX_2679 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172136.1 2922184 D 717522 CDS YP_005172137.1 378772404 11810979 2923654..2924064 1 NC_016804.1 hypothetical protein 2924064 11810979 BCGMEX_2680 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172137.1 2923654 D 717522 CDS YP_005172138.1 378772405 11810980 complement(2924132..2924884) 1 NC_016804.1 hypothetical protein 2924884 11810980 BCGMEX_2681c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172138.1 2924132 R 717522 CDS YP_005172139.1 378772406 11810981 complement(2924881..2925576) 1 NC_016804.1 hypothetical protein 2925576 11810981 BCGMEX_2682c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172139.1 2924881 R 717522 CDS YP_005172140.1 378772407 11810982 complement(2925582..2926940) 1 NC_016804.1 protoporphyrinogen IX oxidase 2926940 hemY 11810982 hemY Mycobacterium bovis BCG str. Mexico protoporphyrinogen IX oxidase YP_005172140.1 2925582 R 717522 CDS YP_005172141.1 378772408 11810983 complement(2926937..2928010) 1 NC_016804.1 Differs from Mb2697c by 1aa A269G in Mycobacterium tuberculosis H37Rv, BCG Pasteur, BCG Tokyo and BCG Mexico; Uroporphyrinogen III decarboxylase 2928010 hemE 11810983 hemE Mycobacterium bovis BCG str. Mexico Uroporphyrinogen III decarboxylase YP_005172141.1 2926937 R 717522 CDS YP_005172142.1 378772409 11810984 2928063..2928893 1 NC_016804.1 Enoyl-CoA hydratase 2928893 11810984 BCGMEX_2685 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005172142.1 2928063 D 717522 CDS YP_005172143.1 378772410 11810985 2929155..2929787 1 NC_016804.1 hypothetical protein 2929787 11810985 BCGMEX_2686 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172143.1 2929155 D 717522 CDS YP_005172144.1 378772411 11810986 2929789..2931105 1 NC_016804.1 Differs from Rv2681 by 1aa V196A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2931105 11810986 BCGMEX_2687 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172144.1 2929789 D 717522 CDS YP_005172145.1 378772412 11810987 complement(2931102..2933018) 1 NC_016804.1 1-deoxy-D-xylulose-5-phosphate synthase 2933018 dxs1 11810987 dxs1 Mycobacterium bovis BCG str. Mexico 1-deoxy-D-xylulose-5-phosphate synthase YP_005172145.1 2931102 R 717522 CDS YP_005172146.1 378772413 11810988 2933162..2933659 1 NC_016804.1 Differs from Rv2683 by 1aa, S84L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2933659 11810988 BCGMEX_2689 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172146.1 2933162 D 717522 CDS YP_005172147.1 378772414 11810989 2933664..2934953 1 NC_016804.1 putative arsenic-transport integral membrane protein 2934953 arsA 11810989 arsA Mycobacterium bovis BCG str. Mexico putative arsenic-transport integral membrane protein YP_005172147.1 2933664 D 717522 CDS YP_005172148.1 378772415 11810990 2935033..2936319 1 NC_016804.1 Differs from Rv2685 by 1aa, G378A and Mb2704, by 1aa, G393C in BCG Pasteur, BCG Tokyo and BCG Mexico; putative arsenic-transport integral membrane protein 2936319 arsB1 11810990 arsB1 Mycobacterium bovis BCG str. Mexico putative arsenic-transport integral membrane protein YP_005172148.1 2935033 D 717522 CDS YP_005172149.1 378772416 11810991 complement(2936330..2937088) 1 NC_016804.1 putative antibiotic-transport integral membrane leucine and alanine and valine rich protein ABC transporter 2937088 11810991 BCGMEX_2692c Mycobacterium bovis BCG str. Mexico putative antibiotic-transport integral membrane leucine and alanine and valine rich protein ABC transporter YP_005172149.1 2936330 R 717522 CDS YP_005172150.1 378772417 11810992 complement(2937085..2937798) 1 NC_016804.1 putative antibiotic-transport integral membrane leucine and valine rich protein ABC transporter 2937798 11810992 BCGMEX_2693c Mycobacterium bovis BCG str. Mexico putative antibiotic-transport integral membrane leucine and valine rich protein ABC transporter YP_005172150.1 2937085 R 717522 CDS YP_005172151.1 378772418 11810993 complement(2937795..2938700) 1 NC_016804.1 Differs from Rv2688c by 1aa, T156P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative antibiotic-transport ATP-binding protein ABC transporter 2938700 11810993 BCGMEX_2694c Mycobacterium bovis BCG str. Mexico putative antibiotic-transport ATP-binding protein ABC transporter YP_005172151.1 2937795 R 717522 CDS YP_005172152.1 378772419 11810994 complement(2938895..2940112) 1 NC_016804.1 hypothetical protein 2940112 11810994 BCGMEX_2695c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172152.1 2938895 R 717522 CDS YP_005172153.1 378772420 11810995 complement(2940268..2942259) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transition leads to a slightly longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (663 aa versus 657aa); putative integral membrane alanine and valine and leucine rich protein 2942259 11810995 BCGMEX_2696c Mycobacterium bovis BCG str. Mexico putative integral membrane alanine and valine and leucine rich protein YP_005172153.1 2940268 R 717522 CDS YP_005172154.1 378772421 11810996 2942394..2943077 1 NC_016804.1 Differs from Rv2691 by 1aa, A117T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Trk system potassium uptake protein 2943077 ceoB 11810996 ceoB Mycobacterium bovis BCG str. Mexico Trk system potassium uptake protein YP_005172154.1 2942394 D 717522 CDS YP_005172155.1 378772422 11810997 2943074..2943736 1 NC_016804.1 Differs from Rv2692 by 1aa, V133I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Trk system potassium uptake protein 2943736 ceoC 11810997 ceoC Mycobacterium bovis BCG str. Mexico Trk system potassium uptake protein YP_005172155.1 2943074 D 717522 CDS YP_005172156.1 378772423 11810998 complement(2943747..2944418) 1 NC_016804.1 putative integral membrane alanine and leucine rich protein 2944418 11810998 BCGMEX_2699c Mycobacterium bovis BCG str. Mexico putative integral membrane alanine and leucine rich protein YP_005172156.1 2943747 R 717522 CDS YP_005172157.1 378772424 11810999 complement(2944449..2944817) 1 NC_016804.1 Differs from Rv2694c by 1aa, S68R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2944817 11810999 BCGMEX_2700c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172157.1 2944449 R 717522 CDS YP_005172158.1 378772425 11811000 2944966..2945673 1 NC_016804.1 hypothetical protein 2945673 11811000 BCGMEX_2701 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172158.1 2944966 D 717522 CDS YP_005172159.1 378772426 11811001 complement(2945879..2946658) 1 NC_016804.1 Differs from Rv2696c by 1aa, N164D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2946658 11811001 BCGMEX_2702c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172159.1 2945879 R 717522 CDS YP_005172160.1 378772427 11811002 complement(2946733..2947197) 1 NC_016804.1 deoxyuridine 5'-triphosphate nucleotidohydrolase 2947197 dut 11811002 dut Mycobacterium bovis BCG str. Mexico deoxyuridine 5'-triphosphate nucleotidohydrolase YP_005172160.1 2946733 R 717522 CDS YP_005172161.1 378772428 11811003 2947223..2947708 1 NC_016804.1 transmembrane protein 2947708 11811003 BCGMEX_2704 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005172161.1 2947223 D 717522 CDS YP_005172162.1 378772429 11811004 complement(2947713..2948015) 1 NC_016804.1 hypothetical protein 2948015 11811004 BCGMEX_2705c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172162.1 2947713 R 717522 CDS YP_005172163.1 378772430 11811005 2948253..2948903 1 NC_016804.1 hypothetical protein 2948903 11811005 BCGMEX_2706 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172163.1 2948253 D 717522 CDS YP_005172164.1 378772431 11811006 complement(2948913..2949785) 1 NC_016804.1 inositol-1-monophosphatase 2949785 suhB 11811006 suhB Mycobacterium bovis BCG str. Mexico inositol-1-monophosphatase YP_005172164.1 2948913 R 717522 CDS YP_005172165.1 378772432 11811007 2949908..2950705 1 NC_016804.1 Differs from Rv2702 by 1aa, T203I in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; polyphosphate glucokinase 2950705 ppgK 11811007 ppgK Mycobacterium bovis BCG str. Mexico polyphosphate glucokinase YP_005172165.1 2949908 D 717522 CDS YP_005172166.1 378772433 11811008 2950885..2952471 1 NC_016804.1 RNA polymerase sigma factor 2952471 sigA 11811008 sigA Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005172166.1 2950885 D 717522 CDS YP_005172167.1 378772434 11811009 2952508..2952936 1 NC_016804.1 hypothetical protein 2952936 11811009 BCGMEX_2710 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172167.1 2952508 D 717522 CDS YP_005172168.1 378772435 11811010 complement(2952864..2953253) 1 NC_016804.1 hypothetical protein 2953253 11811010 BCGMEX_2711c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172168.1 2952864 R 717522 CDS YP_005172169.1 378772436 11811011 complement(2953250..2953507) 1 NC_016804.1 hypothetical protein 2953507 11811011 BCGMEX_2712c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172169.1 2953250 R 717522 CDS YP_005172170.1 378772437 11811012 2953623..2954597 1 NC_016804.1 putative transmembrane alanine and leucine rich protein 2954597 11811012 BCGMEX_2713 Mycobacterium bovis BCG str. Mexico putative transmembrane alanine and leucine rich protein YP_005172170.1 2953623 D 717522 CDS YP_005172171.1 378772438 11811013 complement(2954598..2954846) 1 NC_016804.1 hypothetical protein 2954846 11811013 BCGMEX_2714c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172171.1 2954598 R 717522 CDS YP_005172172.1 378772439 11811014 2954889..2955335 1 NC_016804.1 Differs from Rv2709 by 1aa, S35T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 2955335 11811014 BCGMEX_2715 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172172.1 2954889 D 717522 CDS YP_005172173.1 378772440 11811015 2955511..2956482 1 NC_016804.1 RNA polymerase sigma factor 2956482 sigB 11811015 sigB Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005172173.1 2955511 D 717522 CDS YP_005172174.1 378772441 11811016 2956615..2957307 1 NC_016804.1 iron-dependent repressor and activator 2957307 ideR 11811016 ideR Mycobacterium bovis BCG str. Mexico iron-dependent repressor and activator YP_005172174.1 2956615 D 717522 CDS YP_005172175.1 378772442 11811017 complement(2957320..2958378) 1 NC_016804.1 hypothetical protein 2958378 11811017 BCGMEX_2718c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172175.1 2957320 R 717522 CDS YP_005172176.1 378772443 11811018 2958491..2959897 1 NC_016804.1 pyridine nucleotide transhydrogenase 2959897 sthA 11811018 sthA Mycobacterium bovis BCG str. Mexico pyridine nucleotide transhydrogenase YP_005172176.1 2958491 D 717522 CDS YP_005172177.1 378772444 11811019 2960115..2961089 1 NC_016804.1 Differs from Rv2714 by 2aa, W181S, A245V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2961089 11811019 BCGMEX_2720 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172177.1 2960115 D 717522 CDS YP_005172178.1 378772445 11811020 2961148..2962173 1 NC_016804.1 putative hydrolase 2962173 11811020 BCGMEX_2721 Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005172178.1 2961148 D 717522 CDS YP_005172179.1 378772446 11811021 2962222..2962908 1 NC_016804.1 hypothetical protein 2962908 11811021 BCGMEX_2722 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172179.1 2962222 D 717522 CDS YP_005172180.1 378772447 11811022 complement(2962917..2963411) 1 NC_016804.1 hypothetical protein 2963411 11811022 BCGMEX_2723c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172180.1 2962917 R 717522 CDS YP_005172181.1 378772448 11811023 complement(2963463..2963927) 1 NC_016804.1 NrdR family transcriptional regulator 2963927 nrdR 11811023 nrdR Mycobacterium bovis BCG str. Mexico NrdR family transcriptional regulator YP_005172181.1 2963463 R 717522 CDS YP_005172182.1 378772449 11811024 complement(2964090..2964587) 1 NC_016804.1 Differs from Rv2719c by 1aa, H124Y in Mycobacteium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; membrane protein 2964587 11811024 BCGMEX_2725c Mycobacterium bovis BCG str. Mexico membrane protein YP_005172182.1 2964090 R 717522 CDS YP_005172183.1 378772450 11811025 2964895..2965548 1 NC_016804.1 Differs from Rv2720 by 1aa, A98V by Mycobacterium bovis BCG Pasteur, BCG Tokio and BCG Mexico; LexA repressor 2965548 lexA 11811025 lexA Mycobacterium bovis BCG str. Mexico LexA repressor YP_005172183.1 2964895 D 717522 CDS YP_005172184.1 378772451 11811026 complement(2965570..2967669) 1 NC_016804.1 Differs from Rv2721c and Mb2740c by 2aa, S251G, A326T in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane alanine and glycine rich protein 2967669 11811026 BCGMEX_2727c Mycobacterium bovis BCG str. Mexico putative transmembrane alanine and glycine rich protein YP_005172184.1 2965570 R 717522 CDS YP_005172185.1 378772452 11811027 2967685..2967933 1 NC_016804.1 hypothetical protein 2967933 11811027 BCGMEX_2728 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172185.1 2967685 D 717522 CDS YP_005172186.1 378772453 11811028 2967959..2969152 1 NC_016804.1 putative integral membrane protein 2969152 11811028 BCGMEX_2729 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172186.1 2967959 D 717522 CDS YP_005172187.1 378772454 11811029 complement(2969181..2970341) 1 NC_016804.1 Differs from Rv2724c by 1aa, T127I, and from Mb2743c by 1aa, P33A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyl-CoA dehydrogenase 2970341 fadE20 11811029 fadE20 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005172187.1 2969181 R 717522 CDS YP_005172188.1 378772455 11811030 complement(2970477..2971964) 1 NC_016804.1 Differs from Rv2725c and Mb2744c by 1aa, D218G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative GTP-binding protein 2971964 hflX 11811030 hflX Mycobacterium bovis BCG str. Mexico putative GTP-binding protein YP_005172188.1 2970477 R 717522 CDS YP_005172189.1 378772456 11811031 complement(2971981..2972850) 1 NC_016804.1 diaminopimelate epimerase 2972850 dapF 11811031 dapF Mycobacterium bovis BCG str. Mexico diaminopimelate epimerase YP_005172189.1 2971981 R 717522 CDS YP_005172190.1 378772457 11811032 complement(2972875..2973819) 1 NC_016804.1 tRNA delta(2)-isopentenylpyrophosphate transferase 2973819 miaA 11811032 miaA Mycobacterium bovis BCG str. Mexico tRNA delta(2)-isopentenylpyrophosphate transferase YP_005172190.1 2972875 R 717522 CDS YP_005172191.1 378772458 11811033 complement(2973816..2974511) 1 NC_016804.1 hypothetical protein 2974511 11811033 BCGMEX_2734c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172191.1 2973816 R 717522 CDS YP_005172192.1 378772459 11811034 complement(2974620..2975525) 1 NC_016804.1 Differs from Rv2729c by 3aa, L41F, E202A, V266A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane alanine and valine and leucine rich protein 2975525 11811034 BCGMEX_2735c Mycobacterium bovis BCG str. Mexico putative integral membrane alanine and valine and leucine rich protein YP_005172192.1 2974620 R 717522 CDS YP_005172193.1 378772460 11811035 2975592..2976068 1 NC_016804.1 hypothetical protein 2976068 11811035 BCGMEX_2736 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172193.1 2975592 D 717522 CDS YP_005172194.1 378772461 11811036 2976076..2977428 1 NC_016804.1 hypothetical protein 2977428 11811036 BCGMEX_2737 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172194.1 2976076 D 717522 CDS YP_005172195.1 378772462 11811037 complement(2977425..2978039) 1 NC_016804.1 putative transmembrane protein 2978039 11811037 BCGMEX_2738c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172195.1 2977425 R 717522 CDS YP_005172196.1 378772463 11811038 complement(2978036..2979574) 1 NC_016804.1 dimethylallyl adenosine tRNA methylthiotransferase 2979574 miaB 11811038 miaB Mycobacterium bovis BCG str. Mexico dimethylallyl adenosine tRNA methylthiotransferase YP_005172196.1 2978036 R 717522 CDS YP_005172197.1 378772464 11811039 2979871..2980725 1 NC_016804.1 hypothetical protein 2980725 11811039 BCGMEX_2740 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172197.1 2979871 D 717522 CDS YP_005172198.1 378772465 11811040 complement(2980610..2981602) 1 NC_016804.1 hypothetical protein 2981602 11811040 BCGMEX_2741c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172198.1 2980610 R 717522 CDS YP_005172199.1 378772466 11811041 complement(2981612..2982136) 1 NC_016804.1 Regulatory protein 2982136 recX 11811041 recX Mycobacterium bovis BCG str. Mexico Regulatory protein YP_005172199.1 2981612 R 717522 CDS YP_005172200.1 378772467 11811042 complement(2982102..2984474) 1 NC_016804.1 protein recA 2984474 recA 11811042 recA Mycobacterium bovis BCG str. Mexico protein recA YP_005172200.1 2982102 R 717522 CDS YP_005172201.1 378772468 11811043 2984669..2984842 1 NC_016804.1 putative cysteine rich protein 2984842 11811043 BCGMEX_2744 Mycobacterium bovis BCG str. Mexico putative cysteine rich protein YP_005172201.1 2984669 D 717522 CDS YP_005172202.1 378772469 11811044 complement(2984856..2985062) 1 NC_016804.1 hypothetical protein 2985062 11811044 BCGMEX_2745c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172202.1 2984856 R 717522 CDS YP_005172203.1 378772470 11811045 complement(2985073..2986239) 1 NC_016804.1 transferase 2986239 11811045 BCGMEX_2746c Mycobacterium bovis BCG str. Mexico transferase YP_005172203.1 2985073 R 717522 CDS YP_005172204.1 378772471 11811046 2986283..2986732 1 NC_016804.1 Epoxide hydrolase 2986732 ephG 11811046 ephG Mycobacterium bovis BCG str. Mexico Epoxide hydrolase YP_005172204.1 2986283 D 717522 CDS YP_005172205.1 378772472 11811047 2986964..2986996 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo,BCG Mexico and Mycobacterium bovis, deletions of a single base leads to frameshifted products PE_PGRS47a (10 aa) and PE_PGRS47b (424 aa), respectively; PE-PGRS family protein 2986996 PE_PGRS47a 11811047 PE_PGRS47a Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005172205.1 2986964 D 717522 CDS YP_005172206.1 378772473 11811048 2987008..2988282 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, deletions of a single base and of 84 bp leads to a shorter product with a different 5' start compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Also has lost 174 bp compared to Mb2761; PE PGRS family protein 2988282 PE_PGRS47 11811048 PE_PGRS47 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005172206.1 2987008 D 717522 CDS YP_005172207.1 378772474 11811049 complement(2988306..2988554) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2742c exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a 23bp insertion splits Rv2742c into two parts; putative arginine rich protein 2988554 11811049 BCGMEX_2750c Mycobacterium bovis BCG str. Mexico putative arginine rich protein YP_005172207.1 2988306 R 717522 CDS YP_005172208.1 378772475 11811050 complement(2988575..2989162) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2742c exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a 23bp insertion splits Rv2742c into two parts; putative arginine rich protein 2989162 11811050 BCGMEX_2751c Mycobacterium bovis BCG str. Mexico putative arginine rich protein YP_005172208.1 2988575 R 717522 CDS YP_005172209.1 378772476 11811051 complement(2989234..2990046) 1 NC_016804.1 putative membrane alanine rich protein 2990046 11811051 BCGMEX_2752c Mycobacterium bovis BCG str. Mexico putative membrane alanine rich protein YP_005172209.1 2989234 R 717522 CDS YP_005172210.1 378772477 11811052 complement(2990065..2990877) 1 NC_016804.1 Differs from Mb2765c by 1aa, K153Q in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 2990877 11811052 BCGMEX_2753c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172210.1 2990065 R 717522 CDS YP_005172211.1 378772478 11811053 complement(2991007..2991345) 1 NC_016804.1 putative transcriptional regulatory protein 2991345 11811053 BCGMEX_2754c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172211.1 2991007 R 717522 CDS YP_005172212.1 378772479 11811054 complement(2991416..2992045) 1 NC_016804.1 putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2992045 pgsA3 11811054 pgsA3 Mycobacterium bovis BCG str. Mexico putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_005172212.1 2991416 R 717522 CDS YP_005172213.1 378772480 11811055 2992076..2992600 1 NC_016804.1 acetyltransferase 2992600 11811055 BCGMEX_2756 Mycobacterium bovis BCG str. Mexico acetyltransferase YP_005172213.1 2992076 D 717522 CDS YP_005172214.1 378772481 11811056 complement(2992669..2995320) 1 NC_016804.1 putative cell division transmembrane protein 2995320 ftsK 11811056 ftsK Mycobacterium bovis BCG str. Mexico putative cell division transmembrane protein YP_005172214.1 2992669 R 717522 CDS YP_005172215.1 378772482 11811057 2995319..2995633 1 NC_016804.1 hypothetical protein 2995633 11811057 BCGMEX_2758 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172215.1 2995319 D 717522 CDS YP_005172216.1 378772483 11811058 2995630..2996448 1 NC_016804.1 putative dehydrogenase 2996448 11811058 BCGMEX_2759 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005172216.1 2995630 D 717522 CDS YP_005172217.1 378772484 11811059 2996452..2997342 1 NC_016804.1 hypothetical protein 2997342 11811059 BCGMEX_2760 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172217.1 2996452 D 717522 CDS YP_005172218.1 378772485 11811060 complement(2997329..2999005) 1 NC_016804.1 hypothetical protein 2999005 11811060 BCGMEX_2761c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172218.1 2997329 R 717522 CDS YP_005172219.1 378772486 11811061 complement(2999036..2999938) 1 NC_016804.1 dihydrodipicolinate synthase 2999938 dapA 11811061 dapA Mycobacterium bovis BCG str. Mexico dihydrodipicolinate synthase YP_005172219.1 2999036 R 717522 CDS YP_005172220.1 378772487 11811062 complement(3000007..3000759) 1 NC_016804.1 Thymidylate synthase 3000759 thyX 11811062 thyX Mycobacterium bovis BCG str. Mexico Thymidylate synthase YP_005172220.1 3000007 R 717522 CDS YP_005172221.1 378772488 11811063 complement(3001003..3001278) 1 NC_016804.1 putative type I restriction-modification system specificity determinant 3001278 hsdS' 11811063 hsdS' Mycobacterium bovis BCG str. Mexico putative type I restriction-modification system specificity determinant YP_005172221.1 3001003 R 717522 CDS YP_005172222.1 378772489 11811064 complement(3001275..3002897) 1 NC_016804.1 Differs from Rv2756c by 1aa, P306L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative type I restriction/modification system DNA methylase 3002897 hsdM 11811064 hsdM Mycobacterium bovis BCG str. Mexico putative type I restriction/modification system DNA methylase YP_005172222.1 3001275 R 717522 CDS YP_005172223.1 378772490 11811065 complement(3002984..3003400) 1 NC_016804.1 hypothetical protein 3003400 11811065 BCGMEX_2766c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172223.1 3002984 R 717522 CDS YP_005172224.1 378772491 11811066 complement(3003397..3003663) 1 NC_016804.1 hypothetical protein 3003663 11811066 BCGMEX_2767c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172224.1 3003397 R 717522 CDS YP_005172225.1 378772492 11811067 complement(3003689..3004084) 1 NC_016804.1 hypothetical protein 3004084 11811067 BCGMEX_2768c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172225.1 3003689 R 717522 CDS YP_005172226.1 378772493 11811068 complement(3004081..3004350) 1 NC_016804.1 hypothetical protein 3004350 11811068 BCGMEX_2769c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172226.1 3004081 R 717522 CDS YP_005172227.1 378772494 11811069 complement(3004360..3005454) 1 NC_016804.1 putative type I restriction/modification system specificity determinant 3005454 hsdS 11811069 hsdS Mycobacterium bovis BCG str. Mexico putative type I restriction/modification system specificity determinant YP_005172227.1 3004360 R 717522 CDS YP_005172228.1 378772495 11811070 complement(3005451..3005723) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2762c exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transition splits Rv2762c into 2 parts; hypothetical protein 3005723 11811070 BCGMEX_2771c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172228.1 3005451 R 717522 CDS YP_005172229.1 378772496 11811071 complement(3005739..3005870) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2762c exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transition splits Rv2762c into 2 parts; hypothetical protein 3005870 11811071 BCGMEX_2772c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172229.1 3005739 R 717522 CDS YP_005172230.1 378772497 11811072 complement(3005944..3006423) 1 NC_016804.1 putative dihydrofolate reductase 3006423 dfrA 11811072 dfrA Mycobacterium bovis BCG str. Mexico putative dihydrofolate reductase YP_005172230.1 3005944 R 717522 CDS YP_005172231.1 378772498 11811073 complement(3006494..3007285) 1 NC_016804.1 Thymidylate synthase 3007285 thyA 11811073 thyA Mycobacterium bovis BCG str. Mexico Thymidylate synthase YP_005172231.1 3006494 R 717522 CDS YP_005172232.1 378772499 11811074 3007450..3008187 1 NC_016804.1 Differs from Rv2765 and Mb2787 by 1aa, I129M in BCG Pasteur, BCG Tokyo and BCG Mexico; hydrolase 3008187 11811074 BCGMEX_2775 Mycobacterium bovis BCG str. Mexico hydrolase YP_005172232.1 3007450 D 717522 CDS YP_005172233.1 378772500 11811075 complement(3008402..3009184) 1 NC_016804.1 3-ketoacyl-ACP reductase 3009184 fabG 11811075 fabG Mycobacterium bovis BCG str. Mexico 3-ketoacyl-ACP reductase YP_005172233.1 3008402 R 717522 CDS YP_005172234.1 378772501 11811076 complement(3009181..3009534) 1 NC_016804.1 Differs from Rv2767c and Mb2789c by 1aa, L26S in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3009534 11811076 BCGMEX_2777c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172234.1 3009181 R 717522 CDS YP_005172235.1 378772502 11811077 complement(3009708..3010892) 1 NC_016804.1 Differs from Rv2768c by 1aa, R263P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3010892 PPE43 11811077 PPE43 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172235.1 3009708 R 717522 CDS YP_005172236.1 378772503 11811078 complement(3010972..3011799) 1 NC_016804.1 Differs from Rv2769c by 2aa, S54P, M270V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 3011799 PE27 11811078 PE27 Mycobacterium bovis BCG str. Mexico PE family protein YP_005172236.1 3010972 R 717522 CDS YP_005172237.1 378772504 11811079 complement(3012123..3013271) 1 NC_016804.1 Differs from Rv2770c by 1aa, S194F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3013271 PPE44 11811079 PPE44 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172237.1 3012123 R 717522 CDS YP_005172238.1 378772505 11811080 complement(3013395..3013847) 1 NC_016804.1 Differs from Rv2771c by 1aa, P80L in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3013847 11811080 BCGMEX_2781c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172238.1 3013395 R 717522 CDS YP_005172239.1 378772506 11811081 complement(3013933..3014406) 1 NC_016804.1 putative transmembrane protein 3014406 11811081 BCGMEX_2782c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172239.1 3013933 R 717522 CDS YP_005172240.1 378772507 11811082 complement(3014418..3015155) 1 NC_016804.1 Differs from Rv2773c by 1aa, I204T, and from Mb2795c by 1aa, D138E in BCG Pasteur, BCG Tokyo and BCG Mexico; dihydrodipicolinate reductase 3015155 dapB 11811082 dapB Mycobacterium bovis BCG str. Mexico dihydrodipicolinate reductase YP_005172240.1 3014418 R 717522 CDS YP_005172241.1 378772508 11811083 complement(3015166..3015570) 1 NC_016804.1 hypothetical protein 3015570 11811083 BCGMEX_2784c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172241.1 3015166 R 717522 CDS YP_005172242.1 378772509 11811084 3015723..3016184 1 NC_016804.1 hypothetical protein 3016184 11811084 BCGMEX_2785 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172242.1 3015723 D 717522 CDS YP_005172243.1 378772510 11811085 complement(3016188..3017117) 1 NC_016804.1 Oxidoreductase 3017117 11811085 BCGMEX_2786c Mycobacterium bovis BCG str. Mexico Oxidoreductase YP_005172243.1 3016188 R 717522 CDS YP_005172244.1 378772511 11811086 complement(3017299..3018369) 1 NC_016804.1 hypothetical protein 3018369 11811086 BCGMEX_2787c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172244.1 3017299 R 717522 CDS YP_005172245.1 378772512 11811087 complement(3018527..3018997) 1 NC_016804.1 hypothetical protein 3018997 11811087 BCGMEX_2788c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172245.1 3018527 R 717522 CDS YP_005172246.1 378772513 11811088 complement(3019029..3019568) 1 NC_016804.1 In Mycobacterium bovis, a 24 bp deletion leads to a shorter product compared to its homolog in Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium tuberculosis strain H37Rv (171 aa versus 179 aa) Differs from Rv2779c by 1aa, I9M, and 8 aa longer than Mb2801c; AsnC family transcriptional regulator 3019568 11811088 BCGMEX_2789c Mycobacterium bovis BCG str. Mexico AsnC family transcriptional regulator YP_005172246.1 3019029 R 717522 CDS YP_005172247.1 378772514 11811089 3019634..3020032 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, ald exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Tokio and in Mycobacterium bovis, a frameshift due to a single base deletion splits ald into 2 parts, alda and aldb; Secreted L-alanine dehydrogenase 3020032 ald_a 11811089 ald_a Mycobacterium bovis BCG str. Mexico Secreted L-alanine dehydrogenase YP_005172247.1 3019634 D 717522 CDS YP_005172248.1 378772515 11811090 3020029..3020748 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, ald exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and in Mycobacterium bovis, a frameshift due to a single base deletion splits ald into 2 parts, alda and aldb; Secreted L-alanine dehydrogenase 3020748 aldB 11811090 aldB Mycobacterium bovis BCG str. Mexico Secreted L-alanine dehydrogenase YP_005172248.1 3020029 D 717522 CDS YP_005172249.1 378772516 11811091 complement(3020763..3021797) 1 NC_016804.1 putative 2-nitropropane dioxygenase 3021797 11811091 BCGMEX_2792c Mycobacterium bovis BCG str. Mexico putative 2-nitropropane dioxygenase YP_005172249.1 3020763 R 717522 CDS YP_005172250.1 378772517 11811092 complement(3021858..3023174) 1 NC_016804.1 putative zinc protease 3023174 pepR 11811092 pepR Mycobacterium bovis BCG str. Mexico putative zinc protease YP_005172250.1 3021858 R 717522 CDS YP_005172251.1 378772518 11811093 complement(3023152..3025410) 1 NC_016804.1 polyribonucleotide nucleotidyltransferase 3025410 gpsI 11811093 gpsI Mycobacterium bovis BCG str. Mexico polyribonucleotide nucleotidyltransferase YP_005172251.1 3023152 R 717522 CDS YP_005172252.1 378772519 11811094 complement(3025764..3026279) 1 NC_016804.1 putative lipoprotein 3026279 lppU 11811094 lppU Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172252.1 3025764 R 717522 CDS YP_005172253.1 378772520 11811095 complement(3026292..3026561) 1 NC_016804.1 30S ribosomal protein S15 3026561 rpsO 11811095 rpsO Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S15 YP_005172253.1 3026292 R 717522 CDS YP_005172254.1 378772521 11811096 complement(3026718..3027713) 1 NC_016804.1 riboflavin kinase/FMN adenylyltransferase 3027713 ribF 11811096 ribF Mycobacterium bovis BCG str. Mexico riboflavin kinase/FMN adenylyltransferase YP_005172254.1 3026718 R 717522 CDS YP_005172255.1 378772522 11811097 3027924..3029687 1 NC_016804.1 Differs from Rv2787 and Mb2810 by 1aa, P78T in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3029687 11811097 BCGMEX_2798 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172255.1 3027924 D 717522 CDS YP_005172256.1 378772523 11811098 3029772..3030458 1 NC_016804.1 Differs from Rv2788 by 1aa, A137D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional repressor 3030458 sirR 11811098 sirR Mycobacterium bovis BCG str. Mexico putative transcriptional repressor YP_005172256.1 3029772 D 717522 CDS YP_005172257.1 378772524 11811099 complement(3030519..3031751) 1 NC_016804.1 acyl-CoA dehydrogenase 3031751 fadE21 11811099 fadE21 Mycobacterium bovis BCG str. Mexico acyl-CoA dehydrogenase YP_005172257.1 3030519 R 717522 CDS YP_005172258.1 378772525 11811100 complement(3031777..3032982) 1 NC_016804.1 putative lipid-transfer protein 3032982 ltp1 11811100 ltp1 Mycobacterium bovis BCG str. Mexico putative lipid-transfer protein YP_005172258.1 3031777 R 717522 CDS YP_005172259.1 378772526 11811101 complement(3033015..3034394) 1 NC_016804.1 putative transposase 3034394 11811101 BCGMEX_2802c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172259.1 3033015 R 717522 CDS YP_005172260.1 378772527 11811102 complement(3034394..3034975) 1 NC_016804.1 Differs from Mb2815c by 2aa, A17V, T80E in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative resolvase 3034975 11811102 BCGMEX_2803c Mycobacterium bovis BCG str. Mexico putative resolvase YP_005172260.1 3034394 R 717522 CDS YP_005172261.1 378772528 11811103 complement(3035177..3036073) 1 NC_016804.1 tRNA pseudouridine synthase B 3036073 truB 11811103 truB Mycobacterium bovis BCG str. Mexico tRNA pseudouridine synthase B YP_005172261.1 3035177 R 717522 CDS YP_005172262.1 378772529 11811104 complement(3036070..3036753) 1 NC_016804.1 Differs from Rv2794c by 1aa, V87M in Mycobacterium tuberculosis CDC1551 in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3036753 11811104 BCGMEX_2805c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172262.1 3036070 R 717522 CDS YP_005172263.1 378772530 11811105 complement(3036750..3037724) 1 NC_016804.1 hypothetical protein 3037724 11811105 BCGMEX_2806c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172263.1 3036750 R 717522 CDS YP_005172264.1 378772531 11811106 complement(3037869..3038432) 1 NC_016804.1 Differs from Rv2796c by 1aa, F159C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 3038432 lppV 11811106 lppV Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172264.1 3037869 R 717522 CDS YP_005172265.1 378772532 11811107 complement(3038432..3040120) 1 NC_016804.1 hypothetical protein 3040120 11811107 BCGMEX_2808c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172265.1 3038432 R 717522 CDS YP_005172266.1 378772533 11811108 complement(3040124..3040450) 1 NC_016804.1 hypothetical protein 3040450 11811108 BCGMEX_2809c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172266.1 3040124 R 717522 CDS YP_005172267.1 378772534 11811109 3040581..3041210 1 NC_016804.1 hypothetical protein 3041210 11811109 BCGMEX_2810 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172267.1 3040581 D 717522 CDS YP_005172268.1 378772535 11811110 3041229..3042878 1 NC_016804.1 putative hydrolase 3042878 11811110 BCGMEX_2811 Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005172268.1 3041229 D 717522 CDS YP_005172269.1 378772536 11811111 complement(3042980..3043336) 1 NC_016804.1 hypothetical protein 3043336 11811111 BCGMEX_2812c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172269.1 3042980 R 717522 CDS YP_005172270.1 378772537 11811112 complement(3043593..3044636) 1 NC_016804.1 putative arginine and alanine rich protein 3044636 11811112 BCGMEX_2813c Mycobacterium bovis BCG str. Mexico putative arginine and alanine rich protein YP_005172270.1 3043593 R 717522 CDS YP_005172271.1 378772538 11811113 3044635..3045102 1 NC_016804.1 hypothetical protein 3045102 11811113 BCGMEX_2814 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172271.1 3044635 D 717522 CDS YP_005172272.1 378772539 11811114 complement(3045278..3045907) 1 NC_016804.1 Differs from Rv2804c by 2aa, T58A, V74A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3045907 11811114 BCGMEX_2815c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172272.1 3045278 R 717522 CDS YP_005172273.1 378772540 11811115 3045680..3046084 1 NC_016804.1 Differs from Rv2805 by 1aa, D4G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3046084 11811115 BCGMEX_2816 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172273.1 3045680 D 717522 CDS YP_005172274.1 378772541 11811116 3046081..3046272 1 NC_016804.1 hypothetical protein 3046272 11811116 BCGMEX_2817 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172274.1 3046081 D 717522 CDS YP_005172275.1 378772542 11811117 3046471..3047625 1 NC_016804.1 Differs from Rv2807 by 2aa, V72E, T349M, and from Mb2830 by 1aa, T349M in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3047625 11811117 BCGMEX_2818 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172275.1 3046471 D 717522 CDS YP_005172276.1 378772543 11811118 3047859..3048116 1 NC_016804.1 hypothetical protein 3048116 11811118 BCGMEX_2819 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172276.1 3047859 D 717522 CDS YP_005172277.1 378772544 11811119 3048221..3048532 1 NC_016804.1 Differs from Rv2809 by 1aa, P46T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3048532 11811119 BCGMEX_2820 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172277.1 3048221 D 717522 CDS YP_005172278.1 378772545 11811121 3048952..3049560 1 NC_016804.1 hypothetical protein 3049560 11811121 BCGMEX_2822 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172278.1 3048952 D 717522 CDS YP_005172279.1 378772546 11811122 3049631..3051040 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium tuberculosis strain H37Rv, Rv2812 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 2 bp deletion splits Rv2812 into 2 parts, Mb2835 and Mb2836. Differs from Rv2812 by 1 aa, G395R; putative transposase 3051040 11811122 BCGMEX_2823 Mycobacterium bovis BCG str. Mexico putative transposase YP_005172279.1 3049631 D 717522 CDS YP_005172280.1 378772547 11811123 3051037..3051849 1 NC_016804.1 Differs from Rv2813 by 1aa, V76I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3051849 11811123 BCGMEX_2824 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172280.1 3051037 D 717522 CDS YP_005172281.1 378772548 11811124 complement(3053452..3054288) 1 NC_016804.1 putative transposase 3054288 11811124 BCGMEX_2825c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172281.1 3053452 R 717522 CDS YP_005172282.1 378772549 11811125 complement(3054387..3054713) 1 NC_016804.1 putative transposase 3054713 11811125 BCGMEX_2826c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172282.1 3054387 R 717522 CDS YP_005172283.1 378772550 11811126 complement(3056967..3057308) 1 NC_016804.1 hypothetical protein 3057308 11811126 BCGMEX_2827c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172283.1 3056967 R 717522 CDS YP_005172284.1 378772551 11811127 complement(3057309..3058325) 1 NC_016804.1 hypothetical protein 3058325 11811127 BCGMEX_2828c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172284.1 3057309 R 717522 CDS YP_005172285.1 378772552 11811129 complement(3058575..3059585) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transition introduces a premature stop codon that leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (336 aa versus 382 aa); hypothetical protein 3059585 11811129 BCGMEX_2830c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172285.1 3058575 R 717522 CDS YP_005172286.1 378772553 11811130 complement(3059582..3060709) 1 NC_016804.1 hypothetical protein 3060709 11811130 BCGMEX_2831c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172286.1 3059582 R 717522 CDS YP_005172287.1 378772554 11811131 complement(3060706..3061614) 1 NC_016804.1 Csm4 family CRISPR-associated ramp protein 3061614 11811131 BCGMEX_2832c Mycobacterium bovis BCG str. Mexico Csm4 family CRISPR-associated ramp protein YP_005172287.1 3060706 R 717522 CDS YP_005172288.1 378772555 11811132 complement(3061595..3062305) 1 NC_016804.1 Csm3 family CRISPR-associated ramp protein 3062305 11811132 BCGMEX_2833c Mycobacterium bovis BCG str. Mexico Csm3 family CRISPR-associated ramp protein YP_005172288.1 3061595 R 717522 CDS YP_005172289.1 378772556 11811133 complement(3062315..3062689) 1 NC_016804.1 hypothetical protein 3062689 11811133 BCGMEX_2834c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172289.1 3062315 R 717522 CDS YP_005172290.1 378772557 11811134 complement(3062686..3065124) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 9 bp insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv; hypothetical protein 3065124 11811134 BCGMEX_2835c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172290.1 3062686 R 717522 CDS YP_005172291.1 378772558 11811135 complement(3065121..3066065) 1 NC_016804.1 Differs from Mb2848c by 1aa H56P in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3066065 11811135 BCGMEX_2836c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172291.1 3065121 R 717522 CDS YP_005172292.1 378772559 11811136 complement(3066243..3066890) 1 NC_016804.1 Differs from Rv2825c by 5aa, E2K, C162S, L189V, Q192T, E195A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3066890 11811136 BCGMEX_2837c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172292.1 3066243 R 717522 CDS YP_005172293.1 378772560 11811137 complement(3067060..3067944) 1 NC_016804.1 hypothetical protein 3067944 11811137 BCGMEX_2838c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172293.1 3067060 R 717522 CDS YP_005172294.1 378772561 11811138 complement(3067947..3068834) 1 NC_016804.1 hypothetical protein 3068834 11811138 BCGMEX_2839c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172294.1 3067947 R 717522 CDS YP_005172295.1 378772562 11811139 complement(3069139..3069684) 1 NC_016804.1 Differs from Mb2852c by 1aa E58A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3069684 11811139 BCGMEX_2840c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172295.1 3069139 R 717522 CDS YP_005172296.1 378772563 11811140 complement(3069681..3069950) 1 NC_016804.1 hypothetical protein 3069950 11811140 BCGMEX_2841c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172296.1 3069681 R 717522 CDS YP_005172297.1 378772564 11811141 complement(3069971..3070363) 1 NC_016804.1 hypothetical protein 3070363 11811141 BCGMEX_2842c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172297.1 3069971 R 717522 CDS YP_005172298.1 378772565 11811142 complement(3070360..3070575) 1 NC_016804.1 Differs from Rv2830c by 1aa, V56A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3070575 11811142 BCGMEX_2843c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172298.1 3070360 R 717522 CDS YP_005172299.1 378772566 11811143 3070622..3071371 1 NC_016804.1 Differs from Mb2855 by 1aa, R227C in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; Enoyl-CoA hydratase 3071371 echA16 11811143 echA16 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005172299.1 3070622 D 717522 CDS YP_005172300.1 378772567 11811144 complement(3071450..3072532) 1 NC_016804.1 Differs from Rv2832c and Mb2856c by 1aa, L235F in BCG Pasteur, BCG Tokyo and BCG Mexico; putative SN-glycerol-3-phosphate transport ATP-binding protein ABC transporter 3072532 ugpC 11811144 ugpC Mycobacterium bovis BCG str. Mexico putative SN-glycerol-3-phosphate transport ATP-binding protein ABC transporter YP_005172300.1 3071450 R 717522 CDS YP_005172301.1 378772568 11811146 complement(3073203..3073835) 1 NC_016804.1 In mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base mutation at corresponding position 3093840, in Mycobacterium tuberculosis H37Rv strain, leads to a stop codon and break ugpB in two parts. Differs from Rv2833c by 2aa, I111S, L174P in BCG Pasteur, BCG Tokyo and BCG Mexico; glycerol-3-phosphate ABC transporter periplasmic substrate-binding protein 3073835 ugpBa 11811146 ugpBa Mycobacterium bovis BCG str. Mexico glycerol-3-phosphate ABC transporter periplasmic substrate-binding protein YP_005172301.1 3073203 R 717522 CDS YP_005172302.1 378772569 11811147 complement(3073838..3074665) 1 NC_016804.1 putative sn-glycerol-3-phosphate transport integral membrane protein ABC transporter 3074665 ugpE 11811147 ugpE Mycobacterium bovis BCG str. Mexico putative sn-glycerol-3-phosphate transport integral membrane protein ABC transporter YP_005172302.1 3073838 R 717522 CDS YP_005172303.1 378772570 11811148 complement(3074662..3075573) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium tuberculosis strain H37Rv, ugpA exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base deletion splits ugpA into 2 parts, ugpAa and ugpAb; putative sn-glycerol-3-phosphate transport integral membrane protein ABC transporter 3075573 ugpA 11811148 ugpA Mycobacterium bovis BCG str. Mexico putative sn-glycerol-3-phosphate transport integral membrane protein ABC transporter YP_005172303.1 3074662 R 717522 CDS YP_005172304.1 378772571 11811149 complement(3075660..3076979) 1 NC_016804.1 Differs from Rv2836c by 2aa, H157Q, L350P, and from Mb2861c by 1aa, H157Q in BCG Pasteur, BCG Tokyo and BCG Mexico; putative DNA-damage-inducible protein F 3076979 dinF 11811149 dinF Mycobacterium bovis BCG str. Mexico putative DNA-damage-inducible protein F YP_005172304.1 3075660 R 717522 CDS YP_005172305.1 378772572 11811150 complement(3076986..3077996) 1 NC_016804.1 hypothetical protein 3077996 11811150 BCGMEX_2851c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172305.1 3076986 R 717522 CDS YP_005172306.1 378772573 11811151 complement(3077971..3078522) 1 NC_016804.1 ribosome-binding factor A 3078522 rbfA 11811151 rbfA Mycobacterium bovis BCG str. Mexico ribosome-binding factor A YP_005172306.1 3077971 R 717522 CDS YP_005172307.1 378772574 11811152 complement(3078522..3081224) 1 NC_016804.1 translation initiation factor IF-2 3081224 infB 11811152 infB Mycobacterium bovis BCG str. Mexico translation initiation factor IF-2 YP_005172307.1 3078522 R 717522 CDS YP_005172308.1 378772575 11811153 complement(3081310..3081609) 1 NC_016804.1 hypothetical protein 3081609 11811153 BCGMEX_2854c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172308.1 3081310 R 717522 CDS YP_005172309.1 378772576 11811154 complement(3081736..3082779) 1 NC_016804.1 Transcription elongation protein 3082779 nusA 11811154 nusA Mycobacterium bovis BCG str. Mexico Transcription elongation protein YP_005172309.1 3081736 R 717522 CDS YP_005172310.1 378772577 11811155 complement(3082776..3083327) 1 NC_016804.1 ribosome maturation factor 3083327 rimP 11811155 rimP Mycobacterium bovis BCG str. Mexico ribosome maturation factor YP_005172310.1 3082776 R 717522 CDS YP_005172311.1 378772578 11811156 3083522..3084067 1 NC_016804.1 putative transmembrane alanine rich protein 3084067 11811156 BCGMEX_2857 Mycobacterium bovis BCG str. Mexico putative transmembrane alanine rich protein YP_005172311.1 3083522 D 717522 CDS YP_005172312.1 378772579 11811157 3084064..3084552 1 NC_016804.1 hypothetical protein 3084552 11811157 BCGMEX_2858 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172312.1 3084064 D 717522 CDS YP_005172313.1 378772580 11811158 complement(3084553..3086301) 1 NC_016804.1 Differs from Rv2845c by 2aa, R177H, T232A in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; prolyl-tRNA synthetase 3086301 proS 11811158 proS Mycobacterium bovis BCG str. Mexico prolyl-tRNA synthetase YP_005172313.1 3084553 R 717522 CDS YP_005172314.1 378772581 11811159 complement(3086390..3087982) 1 NC_016804.1 Differs from Rv2846c by 1aa, R15T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane efflux protein 3087982 efpA 11811159 efpA Mycobacterium bovis BCG str. Mexico putative transmembrane efflux protein YP_005172314.1 3086390 R 717522 CDS YP_005172315.1 378772582 11811160 complement(3088005..3089222) 1 NC_016804.1 multifunctional enzyme siroheme synthase 3089222 cysG 11811160 cysG Mycobacterium bovis BCG str. Mexico multifunctional enzyme siroheme synthase YP_005172315.1 3088005 R 717522 CDS YP_005172316.1 378772583 11811161 complement(3089499..3090872) 1 NC_016804.1 Cobyrinic acid a,c-diamide synthase 3090872 cobB 11811161 cobB Mycobacterium bovis BCG str. Mexico Cobyrinic acid a,c-diamide synthase YP_005172316.1 3089499 R 717522 CDS YP_005172317.1 378772584 11811162 complement(3090872..3091495) 1 NC_016804.1 Differs from Rv2849c by 1aa C120W in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Cob(I)alamin adenosyltransferase 3091495 cobO 11811162 cobO Mycobacterium bovis BCG str. Mexico Cob(I)alamin adenosyltransferase YP_005172317.1 3090872 R 717522 CDS YP_005172318.1 378772585 11811163 complement(3091516..3093405) 1 NC_016804.1 Differs from Rv2850c by 2aa, Q273R, S446G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative magnesium chelatase 3093405 11811163 BCGMEX_2864c Mycobacterium bovis BCG str. Mexico putative magnesium chelatase YP_005172318.1 3091516 R 717522 CDS YP_005172319.1 378772586 11811164 complement(3093402..3093872) 1 NC_016804.1 hypothetical protein 3093872 11811164 BCGMEX_2865c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172319.1 3093402 R 717522 CDS YP_005172320.1 378772587 11811165 complement(3093931..3095412) 1 NC_016804.1 Malate:quinone oxidoreductase 3095412 mqo 11811165 mqo Mycobacterium bovis BCG str. Mexico Malate:quinone oxidoreductase YP_005172320.1 3093931 R 717522 CDS YP_005172321.1 378772588 11811166 3095619..3097412 1 NC_016804.1 Differs from Rv2853 by 3aa, N227K, G228R, D232G, and 18aa deletion, and from Mb2878 by 1aa, D184G, and same 18aa deletion in BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 3097412 PE_PGRS48 11811166 PE_PGRS48 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005172321.1 3095619 D 717522 CDS YP_005172322.1 378772589 11811167 3097449..3098489 1 NC_016804.1 hypothetical protein 3098489 11811167 BCGMEX_2868 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172322.1 3097449 D 717522 CDS YP_005172323.1 378772590 11811168 3098502..3099881 1 NC_016804.1 NADPH-dependent mycothiol reductase 3099881 mtr 11811168 mtr Mycobacterium bovis BCG str. Mexico NADPH-dependent mycothiol reductase YP_005172323.1 3098502 D 717522 CDS YP_005172324.1 378772591 11811169 3099981..3101099 1 NC_016804.1 putative nickel-transport integral membrane protein 3101099 nicT 11811169 nicT Mycobacterium bovis BCG str. Mexico putative nickel-transport integral membrane protein YP_005172324.1 3099981 D 717522 CDS YP_005172325.1 378772592 11811170 3101165..3101497 1 NC_016804.1 Truncated hydrogenase nickel incorporation protein 3101497 11811170 BCGMEX_2871 Mycobacterium bovis BCG str. Mexico Truncated hydrogenase nickel incorporation protein YP_005172325.1 3101165 D 717522 CDS YP_005172326.1 378772593 11811171 3101509..3101724 1 NC_016804.1 Truncated hydrogenase nickel incorporation protein 3101724 11811171 BCGMEX_2872 Mycobacterium bovis BCG str. Mexico Truncated hydrogenase nickel incorporation protein YP_005172326.1 3101509 D 717522 CDS YP_005172327.1 378772594 11811172 complement(3101880..3102656) 1 NC_016804.1 short-chain dehydrogenase 3102656 11811172 BCGMEX_2873c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005172327.1 3101880 R 717522 CDS YP_005172328.1 378772595 11811173 complement(3102653..3104020) 1 NC_016804.1 putative aldehyde dehydrogenase 3104020 aldC 11811173 aldC Mycobacterium bovis BCG str. Mexico putative aldehyde dehydrogenase YP_005172328.1 3102653 R 717522 CDS YP_005172329.1 378772596 11811174 complement(3104017..3104943) 1 NC_016804.1 putative amidotransferase 3104943 11811174 BCGMEX_2875c Mycobacterium bovis BCG str. Mexico putative amidotransferase YP_005172329.1 3104017 R 717522 CDS YP_005172330.1 378772597 11811175 complement(3104924..3106297) 1 NC_016804.1 putative glutamine synthetase 3106297 glnA4 11811175 glnA4 Mycobacterium bovis BCG str. Mexico putative glutamine synthetase YP_005172330.1 3104924 R 717522 CDS YP_005172331.1 378772598 11811176 complement(3106457..3107314) 1 NC_016804.1 methionine aminopeptidase 3107314 mapB 11811176 mapB Mycobacterium bovis BCG str. Mexico methionine aminopeptidase YP_005172331.1 3106457 R 717522 CDS YP_005172332.1 378772599 11811177 complement(3107356..3107940) 1 NC_016804.1 Differs from Rv2862c by 2aa, P18R, R50C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3107940 11811177 BCGMEX_2878c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172332.1 3107356 R 717522 CDS YP_005172333.1 378772600 11811178 3108289..3108669 1 NC_016804.1 hypothetical protein 3108669 11811178 BCGMEX_2879 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172333.1 3108289 D 717522 CDS YP_005172334.1 378772601 11811179 complement(3108751..3110562) 1 NC_016804.1 putative penicillin-binding lipoprotein 3110562 11811179 BCGMEX_2880c Mycobacterium bovis BCG str. Mexico putative penicillin-binding lipoprotein YP_005172334.1 3108751 R 717522 CDS YP_005172335.1 378772602 11811180 3110834..3111115 1 NC_016804.1 hypothetical protein 3111115 11811180 BCGMEX_2881 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172335.1 3110834 D 717522 CDS YP_005172336.1 378772603 11811181 3111119..3111382 1 NC_016804.1 hypothetical protein 3111382 11811181 BCGMEX_2882 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172336.1 3111119 D 717522 CDS YP_005172337.1 378772604 11811182 complement(3111755..3112609) 1 NC_016804.1 hypothetical protein 3112609 11811182 BCGMEX_2883c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172337.1 3111755 R 717522 CDS YP_005172338.1 378772605 11811183 complement(3112665..3113828) 1 NC_016804.1 Differs from Mb2893c by 1aa, D373A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3113828 ispG 11811183 ispG Mycobacterium bovis BCG str. Mexico 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_005172338.1 3112665 R 717522 CDS YP_005172339.1 378772606 11811184 complement(3113845..3115059) 1 NC_016804.1 Differs from Mb2894c by 1aa, T330A, and from Rv2869c by 2aa, F259V, T330A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative zinc metalloprotease 3115059 11811184 BCGMEX_2885c Mycobacterium bovis BCG str. Mexico putative zinc metalloprotease YP_005172339.1 3113845 R 717522 CDS YP_005172340.1 378772607 11811185 complement(3115067..3116308) 1 NC_016804.1 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3116308 dxr 11811185 dxr Mycobacterium bovis BCG str. Mexico 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_005172340.1 3115067 R 717522 CDS YP_005172341.1 378772608 11811186 3116435..3116692 1 NC_016804.1 hypothetical protein 3116692 11811186 BCGMEX_2887 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172341.1 3116435 D 717522 CDS YP_005172342.1 378772609 11811187 3116679..3117122 1 NC_016804.1 Differs from Rv2872 and Mb2897 by 1aa, T72A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3117122 11811187 BCGMEX_2888 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172342.1 3116679 D 717522 CDS YP_005172343.1 378772610 11811188 3117202..3117864 1 NC_016804.1 cell surface lipoprotein 3117864 mpb83 11811188 mpb83 Mycobacterium bovis BCG str. Mexico cell surface lipoprotein YP_005172343.1 3117202 D 717522 CDS YP_005172344.1 378772611 11811189 3117960..3118151 1 NC_016804.1 hypothetical protein 3118151 11811189 BCGMEX_2890 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172344.1 3117960 D 717522 CDS YP_005172345.1 378772612 11811190 3118144..3120231 1 NC_016804.1 Differs from Rv2874 by 1aa, D672Y in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane c-type cytochrome biogenesis protein 3120231 dipZ 11811190 dipZ Mycobacterium bovis BCG str. Mexico putative integral membrane c-type cytochrome biogenesis protein YP_005172345.1 3118144 D 717522 CDS YP_005172346.1 378772613 11811191 3120327..3120908 1 NC_016804.1 immunogenic protein MPB70 3120908 mpb70 11811191 mpb70 Mycobacterium bovis BCG str. Mexico immunogenic protein MPB70 YP_005172346.1 3120327 D 717522 CDS YP_005172347.1 378772614 11811192 3120960..3121274 1 NC_016804.1 Differs from Mb2901 by 1aa, D101G, and from Rv2876 by 2aa, R44W, D101G in BCG Pasteur and BCG Mexico; transmembrane protein 3121274 11811192 BCGMEX_2893 Mycobacterium bovis BCG str. Mexico transmembrane protein YP_005172347.1 3120960 D 717522 CDS YP_005172348.1 378772615 11811193 complement(3121305..3122168) 1 NC_016804.1 Differs from Rv2877c by 1aa, H35Y in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 3122168 11811193 BCGMEX_2894c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172348.1 3121305 R 717522 CDS YP_005172349.1 378772616 11811194 complement(3122173..3122694) 1 NC_016804.1 Soluble secreted antigen 3122694 mpb53 11811194 mpb53 Mycobacterium bovis BCG str. Mexico Soluble secreted antigen YP_005172349.1 3122173 R 717522 CDS YP_005172350.1 378772617 11811195 complement(3122880..3123974) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv2880cand Rv2879c exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base deletion leads to a single product; ribosomal RNA large subunit methyltransferase N 3123974 rlmN 11811195 rlmN Mycobacterium bovis BCG str. Mexico ribosomal RNA large subunit methyltransferase N YP_005172350.1 3122880 R 717522 CDS YP_005172351.1 378772618 11811196 complement(3123997..3124917) 1 NC_016804.1 phosphatidate cytidylyltransferase 3124917 cdsA 11811196 cdsA Mycobacterium bovis BCG str. Mexico phosphatidate cytidylyltransferase YP_005172351.1 3123997 R 717522 CDS YP_005172352.1 378772619 11811197 complement(3124940..3125497) 1 NC_016804.1 Differs from Mb2906c and Rv2882c by 1aa, L50P in BCG Pasteur, BCG Tokyo and BCG Mexico; ribosome recycling factor 3125497 frr 11811197 frr Mycobacterium bovis BCG str. Mexico ribosome recycling factor YP_005172352.1 3124940 R 717522 CDS YP_005172353.1 378772620 11811198 complement(3125669..3126454) 1 NC_016804.1 uridylate kinase 3126454 pyrH 11811198 pyrH Mycobacterium bovis BCG str. Mexico uridylate kinase YP_005172353.1 3125669 R 717522 CDS YP_005172354.1 378772621 11811199 3126689..3127447 1 NC_016804.1 putative transcriptional regulatory protein 3127447 11811199 BCGMEX_2900 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172354.1 3126689 D 717522 CDS YP_005172355.1 378772622 11811200 complement(3127526..3128845) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base insertion leads to a truncation resulting in a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (439 aa versus 460 aa); putative transposase 3128845 11811200 BCGMEX_2901c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172355.1 3127526 R 717522 CDS YP_005172356.1 378772623 11811201 complement(3128842..3129729) 1 NC_016804.1 putative resolvase 3129729 11811201 BCGMEX_2902c Mycobacterium bovis BCG str. Mexico putative resolvase YP_005172356.1 3128842 R 717522 CDS YP_005172357.1 378772624 11811202 3129728..3130147 1 NC_016804.1 putative transcriptional regulatory protein 3130147 11811202 BCGMEX_2903 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172357.1 3129728 D 717522 CDS YP_005172358.1 378772625 11811203 complement(3130161..3131582) 1 NC_016804.1 amidase 3131582 amiC 11811203 amiC Mycobacterium bovis BCG str. Mexico amidase YP_005172358.1 3130161 R 717522 CDS YP_005172359.1 378772626 11811204 complement(3131589..3132404) 1 NC_016804.1 Differs from Rv2889c by 1aa, M259T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Translation elongation factor 3132404 tsf 11811204 tsf Mycobacterium bovis BCG str. Mexico Translation elongation factor YP_005172359.1 3131589 R 717522 CDS YP_005172360.1 378772627 11811205 complement(3132416..3133279) 1 NC_016804.1 30S ribosomal protein S2 3133279 rpsB 11811205 rpsB Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S2 YP_005172360.1 3132416 R 717522 CDS YP_005172361.1 378772628 11811206 3133563..3134312 1 NC_016804.1 hypothetical protein 3134312 11811206 BCGMEX_2907 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172361.1 3133563 D 717522 CDS YP_005172362.1 378772629 11811207 complement(3134091..3135317) 1 NC_016804.1 PPE family protein 3135317 PPE45 11811207 PPE45 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172362.1 3134091 R 717522 CDS YP_005172363.1 378772630 11811208 3135717..3136694 1 NC_016804.1 putative oxidoreductase 3136694 11811208 BCGMEX_2909 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172363.1 3135717 D 717522 CDS YP_005172364.1 378772631 11811209 complement(3136691..3137587) 1 NC_016804.1 tyrosine recombinase 3137587 xerC 11811209 xerC Mycobacterium bovis BCG str. Mexico tyrosine recombinase YP_005172364.1 3136691 R 717522 CDS YP_005172365.1 378772632 11811210 complement(3137678..3138529) 1 NC_016804.1 putative mycobactin utilization protein 3138529 viuB 11811210 viuB Mycobacterium bovis BCG str. Mexico putative mycobactin utilization protein YP_005172365.1 3137678 R 717522 CDS YP_005172366.1 378772633 11811211 complement(3138562..3139731) 1 NC_016804.1 Differs from Rv2896c by 2aa, G57E, A153S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3139731 11811211 BCGMEX_2912c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172366.1 3138562 R 717522 CDS YP_005172367.1 378772634 11811212 complement(3139728..3141239) 1 NC_016804.1 hypothetical protein 3141239 11811212 BCGMEX_2913c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172367.1 3139728 R 717522 CDS YP_005172368.1 378772635 11811213 complement(3141239..3141625) 1 NC_016804.1 hypothetical protein 3141625 11811213 BCGMEX_2914c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172368.1 3141239 R 717522 CDS YP_005172369.1 378772636 11811214 complement(3141873..3142703) 1 NC_016804.1 protein fdhD-like protein 3142703 fdhD 11811214 fdhD Mycobacterium bovis BCG str. Mexico protein fdhD-like protein YP_005172369.1 3141873 R 717522 CDS YP_005172370.1 378772637 11811215 complement(3142703..3145042) 1 NC_016804.1 putative formate dehydrogenase 3145042 fdhF 11811215 fdhF Mycobacterium bovis BCG str. Mexico putative formate dehydrogenase YP_005172370.1 3142703 R 717522 CDS YP_005172371.1 378772638 11811216 complement(3145100..3145405) 1 NC_016804.1 hypothetical protein 3145405 11811216 BCGMEX_2917c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172371.1 3145100 R 717522 CDS YP_005172372.1 378772639 11811217 complement(3145459..3146253) 1 NC_016804.1 Differs from Mb2926c by 1aa, R106H in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ribonuclease HII 3146253 rnhB 11811217 rnhB Mycobacterium bovis BCG str. Mexico ribonuclease HII YP_005172372.1 3145459 R 717522 CDS YP_005172373.1 378772640 11811218 complement(3146267..3147151) 1 NC_016804.1 Differs from Rv2903c by 1aa, N2564D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Signal peptidase I 3147151 lepB 11811218 lepB Mycobacterium bovis BCG str. Mexico Signal peptidase I YP_005172373.1 3146267 R 717522 CDS YP_005172374.1 378772641 11811219 complement(3147209..3147550) 1 NC_016804.1 50S ribosomal protein L19 3147550 rplS 11811219 rplS Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L19 YP_005172374.1 3147209 R 717522 CDS YP_005172375.1 378772642 11811220 3147925..3148869 1 NC_016804.1 putative lipoprotein 3148869 lppW 11811220 lppW Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172375.1 3147925 D 717522 CDS YP_005172376.1 378772643 11811221 complement(3148962..3149654) 1 NC_016804.1 tRNA (Guanine37-N1) -methyltransferase 3149654 trmD 11811221 trmD Mycobacterium bovis BCG str. Mexico tRNA (Guanine37-N1) -methyltransferase YP_005172376.1 3148962 R 717522 CDS YP_005172377.1 378772644 11811222 complement(3149658..3150188) 1 NC_016804.1 16S rRNA processing protein 3150188 rimM 11811222 rimM Mycobacterium bovis BCG str. Mexico 16S rRNA processing protein YP_005172377.1 3149658 R 717522 CDS YP_005172378.1 378772645 11811223 complement(3150202..3150444) 1 NC_016804.1 hypothetical protein 3150444 11811223 BCGMEX_2924c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172378.1 3150202 R 717522 CDS YP_005172379.1 378772646 11811224 complement(3150452..3150940) 1 NC_016804.1 30S ribosomal protein S16 3150940 rpsP 11811224 rpsP Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S16 YP_005172379.1 3150452 R 717522 CDS YP_005172380.1 378772647 11811225 complement(3151124..3151567) 1 NC_016804.1 hypothetical protein 3151567 11811225 BCGMEX_2926c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172380.1 3151124 R 717522 CDS YP_005172381.1 378772648 11811226 3151636..3152511 1 NC_016804.1 putative D-alanyl-D-alanine carboxypeptidase 3152511 dacB2 11811226 dacB2 Mycobacterium bovis BCG str. Mexico putative D-alanyl-D-alanine carboxypeptidase YP_005172381.1 3151636 D 717522 CDS YP_005172382.1 378772649 11811227 complement(3152571..3153158) 1 NC_016804.1 TetR family transcriptional regulator 3153158 11811227 BCGMEX_2928c Mycobacterium bovis BCG str. Mexico TetR family transcriptional regulator YP_005172382.1 3152571 R 717522 CDS YP_005172383.1 378772650 11811228 complement(3153160..3154995) 1 NC_016804.1 hypothetical protein 3154995 11811228 BCGMEX_2929c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172383.1 3153160 R 717522 CDS YP_005172384.1 378772651 11811229 complement(3155064..3156821) 1 NC_016804.1 putative serine/threonine-protein kinase 3156821 pknI 11811229 pknI Mycobacterium bovis BCG str. Mexico putative serine/threonine-protein kinase YP_005172384.1 3155064 R 717522 CDS YP_005172385.1 378772652 11811230 complement(3156865..3157977) 1 NC_016804.1 hypothetical protein 3157977 11811230 BCGMEX_2931c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172385.1 3156865 R 717522 CDS YP_005172386.1 378772653 11811231 complement(3158005..3159582) 1 NC_016804.1 putative signal recognition particle protein 3159582 ffh 11811231 ffh Mycobacterium bovis BCG str. Mexico putative signal recognition particle protein YP_005172386.1 3158005 R 717522 CDS YP_005172387.1 378772654 11811232 3159660..3161540 1 NC_016804.1 Differs from Rv2917 by 1aa, L594R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3161540 11811232 BCGMEX_2933 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172387.1 3159660 D 717522 CDS YP_005172388.1 378772655 11811233 complement(3161551..3163977) 1 NC_016804.1 Differs from Rv2918c by 1aa, W494R and Mb2942c by 1aa, L223R in BCG Pasteur, BCG Tokyo and BCG Mexico; PII uridylyl-transferase 3163977 glnD 11811233 glnD Mycobacterium bovis BCG str. Mexico PII uridylyl-transferase YP_005172388.1 3161551 R 717522 CDS YP_005172389.1 378772656 11811234 complement(3164035..3164373) 1 NC_016804.1 nitrogen regulatory protein P-II 3164373 glnB 11811234 glnB Mycobacterium bovis BCG str. Mexico nitrogen regulatory protein P-II YP_005172389.1 3164035 R 717522 CDS YP_005172390.1 378772657 11811235 complement(3164370..3165803) 1 NC_016804.1 putative ammonia channel 3165803 amt 11811235 amt Mycobacterium bovis BCG str. Mexico putative ammonia channel YP_005172390.1 3164370 R 717522 CDS YP_005172391.1 378772658 11811236 complement(3166280..3167548) 1 NC_016804.1 cell division protein ftsY-like protein 3167548 ftsY 11811236 ftsY Mycobacterium bovis BCG str. Mexico cell division protein ftsY-like protein YP_005172391.1 3166280 R 717522 CDS YP_005172392.1 378772659 11811237 complement(3167598..3171215) 1 NC_016804.1 Differs from Rv2922c by 2aa, R364L, G698R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative chromosome partition protein 3171215 smc 11811237 smc Mycobacterium bovis BCG str. Mexico putative chromosome partition protein YP_005172392.1 3167598 R 717522 CDS YP_005172393.1 378772660 11811238 complement(3171227..3171508) 1 NC_016804.1 acylphosphatase 3171508 acyP 11811238 acyP Mycobacterium bovis BCG str. Mexico acylphosphatase YP_005172393.1 3171227 R 717522 CDS YP_005172394.1 378772661 11811239 complement(3171495..3171908) 1 NC_016804.1 hypothetical protein 3171908 11811239 BCGMEX_2940c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172394.1 3171495 R 717522 CDS YP_005172395.1 378772662 11811240 complement(3172010..3172879) 1 NC_016804.1 Formamidopyrimidine-DNA glycosylase 3172879 fpg 11811240 fpg Mycobacterium bovis BCG str. Mexico Formamidopyrimidine-DNA glycosylase YP_005172395.1 3172010 R 717522 CDS YP_005172396.1 378772663 11811241 complement(3173183..3173905) 1 NC_016804.1 ribonuclease III 3173905 rnc 11811241 rnc Mycobacterium bovis BCG str. Mexico ribonuclease III YP_005172396.1 3173183 R 717522 CDS YP_005172397.1 378772664 11811242 complement(3173902..3174525) 1 NC_016804.1 hypothetical protein 3174525 11811242 BCGMEX_2943c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172397.1 3173902 R 717522 CDS YP_005172398.1 378772665 11811243 complement(3174576..3175313) 1 NC_016804.1 hypothetical protein 3175313 11811243 BCGMEX_2944c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172398.1 3174576 R 717522 CDS YP_005172399.1 378772666 11811244 3175552..3176337 1 NC_016804.1 putative thioesterase 3176337 tesA 11811244 tesA Mycobacterium bovis BCG str. Mexico putative thioesterase YP_005172399.1 3175552 D 717522 CDS YP_005172400.1 378772667 11811245 3176324..3176635 1 NC_016804.1 hypothetical protein 3176635 11811245 BCGMEX_2946 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172400.1 3176324 D 717522 CDS YP_005172401.1 378772668 11811246 3177051..3178802 1 NC_016804.1 Differs from Rv2930 by 1aa, V240M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA synthase 3178802 fadD26 11811246 fadD26 Mycobacterium bovis BCG str. Mexico acyl-CoA synthase YP_005172401.1 3177051 D 717522 CDS YP_005172402.1 378772669 11811247 3178799..3184429 1 NC_016804.1 Differs from Rv2931 at several positions in BCG Pasteur, BCG Tokyo and BCG Mexico; phenolpthiocerol synthesis polyketide synthase 3184429 ppsA 11811247 ppsA Mycobacterium bovis BCG str. Mexico phenolpthiocerol synthesis polyketide synthase YP_005172402.1 3178799 D 717522 CDS YP_005172403.1 378772670 11811248 3184426..3189042 1 NC_016804.1 Differs from Mb2957 and Rv2932 at several positions in BCG Pasteur, BCG Tokyo and BCG Mexico; phenolpthiocerol synthesis polyketide synthase 3189042 ppsB 11811248 ppsB Mycobacterium bovis BCG str. Mexico phenolpthiocerol synthesis polyketide synthase YP_005172403.1 3184426 D 717522 CDS YP_005172404.1 378772671 11811249 3189039..3195605 1 NC_016804.1 phenolpthiocerol synthesis type-I polyketide synthase 3195605 ppsC 11811249 ppsC Mycobacterium bovis BCG str. Mexico phenolpthiocerol synthesis type-I polyketide synthase YP_005172404.1 3189039 D 717522 CDS YP_005172405.1 378772672 11811250 3195602..3201085 1 NC_016804.1 Differs from Rv2934 at several positions in BCG Pasteur, BCG Tokyo and BCG Mexico; phenolpthiocerol synthesis type-I polyketide synthase 3201085 ppsD 11811250 ppsD Mycobacterium bovis BCG str. Mexico phenolpthiocerol synthesis type-I polyketide synthase YP_005172405.1 3195602 D 717522 CDS YP_005172406.1 378772673 11811251 3201091..3205557 1 NC_016804.1 Differs from Rv2935 at several positions in BCG Pasteur, BCG Tokyo and BCG Mexico; phenolpthiocerol synthesis type-I polyketide synthase 3205557 ppsE 11811251 ppsE Mycobacterium bovis BCG str. Mexico phenolpthiocerol synthesis type-I polyketide synthase YP_005172406.1 3201091 D 717522 CDS YP_005172407.1 378772674 11811252 3205568..3206563 1 NC_016804.1 Differs from Rv2936 by 1aa, D309H in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative daunorubicin-DIM-transport ATP-binding protein ABC transporter 3206563 drrA 11811252 drrA Mycobacterium bovis BCG str. Mexico putative daunorubicin-DIM-transport ATP-binding protein ABC transporter YP_005172407.1 3205568 D 717522 CDS YP_005172408.1 378772675 11811253 3206560..3207429 1 NC_016804.1 putative daunorubicin-DIM-transport integral membrane protein ABC transporter 3207429 drrB 11811253 drrB Mycobacterium bovis BCG str. Mexico putative daunorubicin-DIM-transport integral membrane protein ABC transporter YP_005172408.1 3206560 D 717522 CDS YP_005172409.1 378772676 11811254 3207426..3208256 1 NC_016804.1 putative daunorubicin-DIM-transport integral membrane protein ABC transporter 3208256 drrC 11811254 drrC Mycobacterium bovis BCG str. Mexico putative daunorubicin-DIM-transport integral membrane protein ABC transporter YP_005172409.1 3207426 D 717522 CDS YP_005172410.1 378772677 11811255 3208303..3209571 1 NC_016804.1 phthiocerol/phthiodiolone dimycocerosyl transferase 3209571 papA5 11811255 papA5 Mycobacterium bovis BCG str. Mexico phthiocerol/phthiodiolone dimycocerosyl transferase YP_005172410.1 3208303 D 717522 CDS YP_005172411.1 378772678 11811256 complement(3209734..3216069) 1 NC_016804.1 multifunctional mycocerosic acid synthase membrane-associated 3216069 mas 11811256 mas Mycobacterium bovis BCG str. Mexico multifunctional mycocerosic acid synthase membrane-associated YP_005172411.1 3209734 R 717522 CDS YP_005172412.1 378772679 11811257 3216689..3218431 1 NC_016804.1 Differs from Mb2966 by 1aa, S2I, and Rv2941 by 1aa, R53Q in BCG Pasteur, BCG Tokio and BCG Mexico; acyl-CoA synthetase 3218431 fadD28 11811257 fadD28 Mycobacterium bovis BCG str. Mexico acyl-CoA synthetase YP_005172412.1 3216689 D 717522 CDS YP_005172413.1 378772680 11811258 3218424..3221186 1 NC_016804.1 transmembrane transport protein 3221186 mmpL7 11811258 mmpL7 Mycobacterium bovis BCG str. Mexico transmembrane transport protein YP_005172413.1 3218424 D 717522 CDS YP_005172414.1 378772681 11811259 3221818..3223059 1 NC_016804.1 putative transposase for insertion sequence element IS1533 3223059 11811259 BCGMEX_2960 Mycobacterium bovis BCG str. Mexico putative transposase for insertion sequence element IS1533 YP_005172414.1 3221818 D 717522 CDS YP_005172415.1 378772682 11811260 3223059..3223589 1 NC_016804.1 putative transposase 3223589 11811260 BCGMEX_2961 Mycobacterium bovis BCG str. Mexico putative transposase YP_005172415.1 3223059 D 717522 CDS YP_005172416.1 378772683 11811261 complement(3223978..3224679) 1 NC_016804.1 putative lipoprotein 3224679 lppX 11811261 lppX Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172416.1 3223978 R 717522 CDS YP_005172417.1 378772684 11811262 complement(3225028..3231366) 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, pks1 and pks15 exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base insertion results in a single product that is more similar to pks1. Differs from Rv2946c by 2aa, G1779V, V1859A, and from Rv2947c by 2aa, A333V, R374G in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyketide synthase1 3231366 pks1 11811262 pks1 Mycobacterium bovis BCG str. Mexico putative polyketide synthase1 YP_005172417.1 3225028 R 717522 CDS YP_005172418.1 378772685 11811263 complement(3231363..3233480) 1 NC_016804.1 long-chain-fatty-acid--CoA ligase 3233480 fadD22 11811263 fadD22 Mycobacterium bovis BCG str. Mexico long-chain-fatty-acid--CoA ligase YP_005172418.1 3231363 R 717522 CDS YP_005172419.1 378772686 11811264 complement(3233497..3234096) 1 NC_016804.1 chorismate--pyruvate lyase 3234096 11811264 BCGMEX_2965c Mycobacterium bovis BCG str. Mexico chorismate--pyruvate lyase YP_005172419.1 3233497 R 717522 CDS YP_005172420.1 378772687 11811265 complement(3234122..3235981) 1 NC_016804.1 Differs from Rv2950c by 1aa, T402A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Fatty-acid-CoA ligase 3235981 fadD29 11811265 fadD29 Mycobacterium bovis BCG str. Mexico Fatty-acid-CoA ligase YP_005172420.1 3234122 R 717522 CDS YP_005172421.1 378772688 11811266 complement(3236629..3237774) 1 NC_016804.1 putative oxidoreductase 3237774 11811266 BCGMEX_2967c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172421.1 3236629 R 717522 CDS YP_005172422.1 378772689 11811267 3237967..3238779 1 NC_016804.1 putative methyltransferase 3238779 11811267 BCGMEX_2968 Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005172422.1 3237967 D 717522 CDS YP_005172423.1 378772690 11811268 3238805..3240061 1 NC_016804.1 Trans-acting enoyl reductase 3240061 11811268 BCGMEX_2969 Mycobacterium bovis BCG str. Mexico Trans-acting enoyl reductase YP_005172423.1 3238805 D 717522 CDS YP_005172424.1 378772691 11811269 complement(3240192..3240917) 1 NC_016804.1 Differs from Rv2954c and Mb2978c by 1aa, Q194R in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3240917 11811269 BCGMEX_2970c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172424.1 3240192 R 717522 CDS YP_005172425.1 378772692 11811270 complement(3241106..3242071) 1 NC_016804.1 Differs from Rv2955c by 1aa, H27R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3242071 11811270 BCGMEX_2971c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172425.1 3241106 R 717522 CDS YP_005172426.1 378772693 11811271 3242194..3242925 1 NC_016804.1 Differs from Rv2956 by 1aa, T237I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3242925 11811271 BCGMEX_2972 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172426.1 3242194 D 717522 CDS YP_005172427.1 378772694 11811272 3242996..3243823 1 NC_016804.1 putative glycosyl transferase 3243823 11811272 BCGMEX_2973 Mycobacterium bovis BCG str. Mexico putative glycosyl transferase YP_005172427.1 3242996 D 717522 CDS YP_005172428.1 378772695 11811273 complement(3244427..3245527) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base insertion leads to a shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; putative glycosyl transferase 3245527 11811273 BCGMEX_2974c Mycobacterium bovis BCG str. Mexico putative glycosyl transferase YP_005172428.1 3244427 R 717522 CDS YP_005172429.1 378772696 11811274 complement(3245628..3246365) 1 NC_016804.1 putative methyltransferase 3246365 11811274 BCGMEX_2975c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005172429.1 3245628 R 717522 CDS YP_005172430.1 378772697 11811275 complement(3246480..3246830) 1 NC_016804.1 hypothetical protein 3246830 11811275 BCGMEX_2976c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172430.1 3246480 R 717522 CDS YP_005172431.1 378772698 11811276 3246810..3247199 1 NC_016804.1 putative transposase 3247199 11811276 BCGMEX_2977 Mycobacterium bovis BCG str. Mexico putative transposase YP_005172431.1 3246810 D 717522 CDS YP_005172432.1 378772699 11811277 complement(3247300..3248649) 1 NC_016804.1 putative glycosyl transferase 3248649 11811277 BCGMEX_2978c Mycobacterium bovis BCG str. Mexico putative glycosyl transferase YP_005172432.1 3247300 R 717522 CDS YP_005172433.1 378772700 11811278 3248763..3249983 1 NC_016804.1 putative integral membrane protein 3249983 11811278 BCGMEX_2979 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172433.1 3248763 D 717522 CDS YP_005172434.1 378772701 11811279 3250056..3250988 1 NC_016804.1 Formyltetrahydrofolate deformylase 3250988 purU 11811279 purU Mycobacterium bovis BCG str. Mexico Formyltetrahydrofolate deformylase YP_005172434.1 3250056 D 717522 CDS YP_005172435.1 378772702 11811280 complement(3251857..3252342) 1 NC_016804.1 phosphopantetheine adenylyltransferase 3252342 coaD 11811280 coaD Mycobacterium bovis BCG str. Mexico phosphopantetheine adenylyltransferase YP_005172435.1 3251857 R 717522 CDS YP_005172436.1 378772703 11811281 complement(3252428..3252994) 1 NC_016804.1 methyltransferase 3252994 11811281 BCGMEX_2982c Mycobacterium bovis BCG str. Mexico methyltransferase YP_005172436.1 3252428 R 717522 CDS YP_005172437.1 378772704 11811282 complement(3253190..3256573) 1 NC_016804.1 pyruvate carboxylase 3256573 pca 11811282 pca Mycobacterium bovis BCG str. Mexico pyruvate carboxylase YP_005172437.1 3253190 R 717522 CDS YP_005172438.1 378772705 11811283 complement(3256598..3257230) 1 NC_016804.1 putative integral membrane protein 3257230 11811283 BCGMEX_2984c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172438.1 3256598 R 717522 CDS YP_005172439.1 378772706 11811284 complement(3257236..3258003) 1 NC_016804.1 hypothetical protein 3258003 11811284 BCGMEX_2985c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172439.1 3257236 R 717522 CDS YP_005172440.1 378772707 11811285 complement(3258100..3259230) 1 NC_016804.1 putative esterase/lipase 3259230 lipN 11811285 lipN Mycobacterium bovis BCG str. Mexico putative esterase/lipase YP_005172440.1 3258100 R 717522 CDS YP_005172441.1 378772708 11811286 3259461..3259631 1 NC_016804.1 hypothetical protein 3259631 11811286 BCGMEX_2987 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172441.1 3259461 D 717522 CDS YP_005172442.1 378772709 11811287 3259628..3260476 1 NC_016804.1 Differs from Rv2971 by 1aa, H152N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 3260476 11811287 BCGMEX_2988 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172442.1 3259628 D 717522 CDS YP_005172443.1 378772710 11811288 complement(3260550..3261263) 1 NC_016804.1 hypothetical protein 3261263 11811288 BCGMEX_2989c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172443.1 3260550 R 717522 CDS YP_005172444.1 378772711 11811289 complement(3261260..3263473) 1 NC_016804.1 Differs from Rv2973c and Mb2998c by 1aa, A6D in BCG Pasteur, BCG Tokyo and BCG Mexico; ATP-dependent DNA helicase 3263473 recG 11811289 recG Mycobacterium bovis BCG str. Mexico ATP-dependent DNA helicase YP_005172444.1 3261260 R 717522 CDS YP_005172445.1 378772712 11811290 complement(3263476..3265137) 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, Rv2975c and Rv2974c exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 2 bp deletion results in a single product that is more similar to Rv2974c; hypothetical protein 3265137 11811290 BCGMEX_2991c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172445.1 3263476 R 717522 CDS YP_005172446.1 378772713 11811291 3265379..3265573 1 NC_016804.1 50S ribosomal protein L28 3265573 11811291 BCGMEX_2992 Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L28 YP_005172446.1 3265379 D 717522 CDS YP_005172447.1 378772714 11811292 complement(3265596..3266279) 1 NC_016804.1 uracil-DNA glycosylase 3266279 ung 11811292 ung Mycobacterium bovis BCG str. Mexico uracil-DNA glycosylase YP_005172447.1 3265596 R 717522 CDS YP_005172448.1 378772715 11811293 complement(3266312..3267313) 1 NC_016804.1 Thiamine-monophosphate kinase 3267313 thiL 11811293 thiL Mycobacterium bovis BCG str. Mexico Thiamine-monophosphate kinase YP_005172448.1 3266312 R 717522 CDS YP_005172449.1 378772716 11811294 complement(3267310..3268689) 1 NC_016804.1 putative transposase 3268689 11811294 BCGMEX_2995c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172449.1 3267310 R 717522 CDS YP_005172450.1 378772717 11811295 complement(3268689..3269273) 1 NC_016804.1 Differs from Rv2979c by 3aa, R14P, A79T, G151D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative resolvase 3269273 11811295 BCGMEX_2996c Mycobacterium bovis BCG str. Mexico putative resolvase YP_005172450.1 3268689 R 717522 CDS YP_005172451.1 378772718 11811296 3269485..3270030 1 NC_016804.1 putative secreted protein 3270030 11811296 BCGMEX_2997 Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005172451.1 3269485 D 717522 CDS YP_005172452.1 378772719 11811297 complement(3270675..3271796) 1 NC_016804.1 In Mycobacterium bovis, a 9 bp deletion leads to a shorter product compared to its homolog in Mycobacterium bovis BCG Pasteur, BCG Mexico and in Mycobacterium tuberculosis strain H37Rv (370 aa versus 373 aa). Differs from Rv2981c by 1aa, A365T, and from Mb3005c by insertion of 3aa, pos:7-9; D-alanine--D-alanine ligase 3271796 ddl 11811297 ddl Mycobacterium bovis BCG str. Mexico D-alanine--D-alanine ligase YP_005172452.1 3270675 R 717522 CDS YP_005172453.1 378772720 11811298 complement(3271874..3272878) 1 NC_016804.1 Differs from Rv2982c by 1aa, A133P in BCG Pasteur, BCG Tokyo and BCG Mexico; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3272878 gpsA 11811298 gpsA Mycobacterium bovis BCG str. Mexico NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_005172453.1 3271874 R 717522 CDS YP_005172454.1 378772721 11811299 3272997..3273641 1 NC_016804.1 hypothetical protein 3273641 11811299 BCGMEX_3000 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172454.1 3272997 D 717522 CDS YP_005172455.1 378772722 11811300 3273733..3275961 1 NC_016804.1 polyphosphate kinase 3275961 ppk 11811300 ppk Mycobacterium bovis BCG str. Mexico polyphosphate kinase YP_005172455.1 3273733 D 717522 CDS YP_005172456.1 378772723 11811301 3276044..3276997 1 NC_016804.1 putative hydrolase 3276997 mutT1 11811301 mutT1 Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005172456.1 3276044 D 717522 CDS YP_005172457.1 378772724 11811302 complement(3277055..3277672) 1 NC_016804.1 Differs from Rv2986c and Mb3010c by 9aa deletion at position 137 in BCG Pasteur, BCG Tokyo and BCG Mexico; putative DNA-binding protein HU-like protein 3277672 hupB 11811302 hupB Mycobacterium bovis BCG str. Mexico putative DNA-binding protein HU-like protein YP_005172457.1 3277055 R 717522 CDS YP_005172458.1 378772725 11811303 complement(3277885..3278481) 1 NC_016804.1 3-isopropylmalate dehydratase small subunit 3278481 leuD 11811303 leuD Mycobacterium bovis BCG str. Mexico 3-isopropylmalate dehydratase small subunit YP_005172458.1 3277885 R 717522 CDS YP_005172459.1 378772726 11811304 complement(3278506..3279927) 1 NC_016804.1 Differs from Rv2988c by 1aa, E343D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 3-isopropylmalate dehydratase large subunit 3279927 leuC 11811304 leuC Mycobacterium bovis BCG str. Mexico 3-isopropylmalate dehydratase large subunit YP_005172459.1 3278506 R 717522 CDS YP_005172460.1 378772727 11811305 3279999..3280700 1 NC_016804.1 putative transcriptional regulatory protein 3280700 11811305 BCGMEX_3006 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172460.1 3279999 D 717522 CDS YP_005172461.1 378772728 11811306 complement(3280711..3281571) 1 NC_016804.1 Differs from Mb3014c by 1aa, A217E in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3281571 11811306 BCGMEX_3007c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172461.1 3280711 R 717522 CDS YP_005172462.1 378772729 11811307 3281834..3282325 1 NC_016804.1 Differs from Rv2991 by 1aa, T93A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3282325 11811307 BCGMEX_3008 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172462.1 3281834 D 717522 CDS YP_005172463.1 378772730 11811310 complement(3282657..3284129) 1 NC_016804.1 Differs from Rv2992c and Mb3016c by 1aa, A420V in BCG Pasteur, BCG Tokyo and BCG Mexico; glutamyl-tRNA synthetase 3284129 gltx 11811310 gltx Mycobacterium bovis BCG str. Mexico glutamyl-tRNA synthetase YP_005172463.1 3282657 R 717522 CDS YP_005172464.1 378772731 11811311 complement(3284126..3284845) 1 NC_016804.1 putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 3284845 11811311 BCGMEX_3010c Mycobacterium bovis BCG str. Mexico putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase YP_005172464.1 3284126 R 717522 CDS YP_005172465.1 378772732 11811312 3285121..3286458 1 NC_016804.1 putative integral membrane protein 3286458 11811312 BCGMEX_3011 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172465.1 3285121 D 717522 CDS YP_005172466.1 378772733 11811313 complement(3286310..3287320) 1 NC_016804.1 Differs from Rv2995c by 1aa L185F in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; 3-isopropylmalate dehydrogenase 3287320 leuB 11811313 leuB Mycobacterium bovis BCG str. Mexico 3-isopropylmalate dehydrogenase YP_005172466.1 3286310 R 717522 CDS YP_005172467.1 378772734 11811314 complement(3287335..3288921) 1 NC_016804.1 D-3-phosphoglycerate dehydrogenase 3288921 serA1 11811314 serA1 Mycobacterium bovis BCG str. Mexico D-3-phosphoglycerate dehydrogenase YP_005172467.1 3287335 R 717522 CDS YP_005172468.1 378772735 11811315 3288951..3290393 1 NC_016804.1 Differs from Rv2997 by 1aa S108C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; dehydrogenase 3290393 11811315 BCGMEX_3014 Mycobacterium bovis BCG str. Mexico dehydrogenase YP_005172468.1 3288951 D 717522 CDS YP_005172469.1 378772736 11811316 3290667..3291128 1 NC_016804.1 hypothetical protein 3291128 11811316 BCGMEX_3015 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172469.1 3290667 D 717522 CDS YP_005172470.1 378772737 11811317 complement(3291077..3291280) 1 NC_016804.1 hypothetical protein 3291280 11811317 BCGMEX_3016c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172470.1 3291077 R 717522 CDS YP_005172471.1 378772738 11811318 3291454..3292419 1 NC_016804.1 Differs from Rv2999 by 1aa, L212M in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 3292419 lppY 11811318 lppY Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172471.1 3291454 D 717522 CDS YP_005172472.1 378772739 11811319 3292464..3293123 1 NC_016804.1 putative transmembrane protein 3293123 11811319 BCGMEX_3018 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172472.1 3292464 D 717522 CDS YP_005172473.1 378772740 11811320 complement(3293437..3294438) 1 NC_016804.1 ketol-acid reductoisomerase 3294438 ilvC 11811320 ilvC Mycobacterium bovis BCG str. Mexico ketol-acid reductoisomerase YP_005172473.1 3293437 R 717522 CDS YP_005172474.1 378772741 11811321 complement(3294476..3294982) 1 NC_016804.1 Differs from Rv3002c and Mb3027c by 1aa, I50T in BCG Pasteur; acetolactate synthase small subunit 3294982 ilvN 11811321 ilvN Mycobacterium bovis BCG str. Mexico acetolactate synthase small subunit YP_005172474.1 3294476 R 717522 CDS YP_005172475.1 378772742 11811322 complement(3294982..3296838) 1 NC_016804.1 acetolactate synthase 3296838 ilvB1 11811322 ilvB1 Mycobacterium bovis BCG str. Mexico acetolactate synthase YP_005172475.1 3294982 R 717522 CDS YP_005172476.1 378772743 11811323 3297200..3297538 1 NC_016804.1 Low molecular weight protein antigen 6 3297538 cfp6 11811323 cfp6 Mycobacterium bovis BCG str. Mexico Low molecular weight protein antigen 6 YP_005172476.1 3297200 D 717522 CDS YP_005172477.1 378772744 11811324 complement(3297545..3298384) 1 NC_016804.1 hypothetical protein 3298384 11811324 BCGMEX_3023c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172477.1 3297545 R 717522 CDS YP_005172478.1 378772745 11811325 3298561..3299682 1 NC_016804.1 Differs from Rv3006 by 1aa, D219G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 3299682 lppZ 11811325 lppZ Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172478.1 3298561 D 717522 CDS YP_005172479.1 378772746 11811326 complement(3299688..3300302) 1 NC_016804.1 putative oxidoreductase 3300302 11811326 BCGMEX_3025c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172479.1 3299688 R 717522 CDS YP_005172480.1 378772747 11811327 3300496..3301119 1 NC_016804.1 hypothetical protein 3301119 11811327 BCGMEX_3026 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172480.1 3300496 D 717522 CDS YP_005172481.1 378772748 11811328 complement(3301116..3302645) 1 NC_016804.1 aspartyl/glutamyl-tRNA amidotransferase subunit B 3302645 gatB 11811328 gatB Mycobacterium bovis BCG str. Mexico aspartyl/glutamyl-tRNA amidotransferase subunit B YP_005172481.1 3301116 R 717522 CDS YP_005172482.1 378772749 11811329 complement(3302675..3303706) 1 NC_016804.1 6-phosphofructokinase 3303706 pfkA 11811329 pfkA Mycobacterium bovis BCG str. Mexico 6-phosphofructokinase YP_005172482.1 3302675 R 717522 CDS YP_005172483.1 378772750 11811330 complement(3303802..3305286) 1 NC_016804.1 Differs from Rv3011c by 3aa, T25A, V59I, L420M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; aspartyl-tRNA amidotransferase subunit A 3305286 gatA 11811330 gatA Mycobacterium bovis BCG str. Mexico aspartyl-tRNA amidotransferase subunit A YP_005172483.1 3303802 R 717522 CDS YP_005172484.1 378772751 11811331 complement(3305283..3305582) 1 NC_016804.1 aspartyl/glutamyl-tRNA amidotransferase subunit C 3305582 gatC 11811331 gatC Mycobacterium bovis BCG str. Mexico aspartyl/glutamyl-tRNA amidotransferase subunit C YP_005172484.1 3305283 R 717522 CDS YP_005172485.1 378772752 11811332 3305667..3306323 1 NC_016804.1 hypothetical protein 3306323 11811332 BCGMEX_3031 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172485.1 3305667 D 717522 CDS YP_005172486.1 378772753 11811333 complement(3306397..3308472) 1 NC_016804.1 DNA ligase 3308472 ligA 11811333 ligA Mycobacterium bovis BCG str. Mexico DNA ligase YP_005172486.1 3306397 R 717522 CDS YP_005172487.1 378772754 11811334 complement(3308503..3309516) 1 NC_016804.1 hypothetical protein 3309516 11811334 BCGMEX_3033c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172487.1 3308503 R 717522 CDS YP_005172488.1 378772755 11811335 3309610..3310239 1 NC_016804.1 putative lipoprotein 3310239 lpqA 11811335 lpqA Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172488.1 3309610 D 717522 CDS YP_005172489.1 378772756 11811336 complement(3310342..3310704) 1 NC_016804.1 putative EsaT-6 like protein 8 3310704 esxQ 11811336 esxQ Mycobacterium bovis BCG str. Mexico putative EsaT-6 like protein 8 YP_005172489.1 3310342 R 717522 CDS YP_005172490.1 378772757 11811337 complement(3310791..3312104) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 56 bp deletion leads to a products lightly different at the N-terminus part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (434 aa versus 437 aa). Differs from Rv3018c by 1aa, A53V, and Mb3043c by 1aa, L328V in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3312104 PPE46 11811337 PPE46 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172490.1 3310791 R 717522 CDS YP_005172491.1 378772758 11811338 complement(3312125..3312211) 1 NC_016804.1 PE family protein 3312211 PE27A 11811338 PE27A Mycobacterium bovis BCG str. Mexico PE family protein YP_005172491.1 3312125 R 717522 CDS YP_005172492.1 378772759 11811339 complement(3312291..3312458) 1 NC_016804.1 hypothetical protein 3312458 11811339 BCGMEX_3038c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172492.1 3312291 R 717522 CDS YP_005172493.1 378772760 11811340 complement(3312507..3312797) 1 NC_016804.1 putative secreted ESAT-6 like protein 9 3312797 esxR 11811340 esxR Mycobacterium bovis BCG str. Mexico putative secreted ESAT-6 like protein 9 YP_005172493.1 3312507 R 717522 CDS YP_005172494.1 378772761 11811341 complement(3312832..3313125) 1 NC_016804.1 PE family protein 3313125 esxS 11811341 esxS Mycobacterium bovis BCG str. Mexico PE family protein YP_005172494.1 3312832 R 717522 CDS YP_005172495.1 378772762 11811342 complement(3313172..3314479) 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, PPE47 and PPE48 exist as 2 separate genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base insertion leads to a single product.; PPE family protein 3314479 PPE47 11811342 PPE47 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172495.1 3313172 R 717522 CDS YP_005172496.1 378772763 11811343 complement(3314476..3314790) 1 NC_016804.1 PE family protein 3314790 PE29 11811343 PE29 Mycobacterium bovis BCG str. Mexico PE family protein YP_005172496.1 3314476 R 717522 CDS YP_005172497.1 378772764 11811344 complement(3315172..3316419) 1 NC_016804.1 Differs from Rv3023c by 1aa T9A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 3316419 11811344 BCGMEX_3043c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172497.1 3315172 R 717522 CDS YP_005172498.1 378772765 11811345 complement(3316582..3317685) 1 NC_016804.1 tRNA (5-methyl aminomethyl-2-thiouridylate)-methyltransferase 3317685 trmU 11811345 trmU Mycobacterium bovis BCG str. Mexico tRNA (5-methyl aminomethyl-2-thiouridylate)-methyltransferase YP_005172498.1 3316582 R 717522 CDS YP_005172499.1 378772766 11811346 complement(3317682..3318863) 1 NC_016804.1 putative cysteine desulfurase 3318863 iscS 11811346 iscS Mycobacterium bovis BCG str. Mexico putative cysteine desulfurase YP_005172499.1 3317682 R 717522 CDS YP_005172500.1 378772767 11811347 complement(3318960..3319874) 1 NC_016804.1 hypothetical protein 3319874 11811347 BCGMEX_3046c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172500.1 3318960 R 717522 CDS YP_005172501.1 378772768 11811348 complement(3319871..3320611) 1 NC_016804.1 hypothetical protein 3320611 11811348 BCGMEX_3047c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172501.1 3319871 R 717522 CDS YP_005172502.1 378772769 11811349 complement(3320872..3321828) 1 NC_016804.1 Differs from Rv3028c by 1aa, V312A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; electron transfer flavoprotein subunit alpha 3321828 fixB 11811349 fixB Mycobacterium bovis BCG str. Mexico electron transfer flavoprotein subunit alpha YP_005172502.1 3320872 R 717522 CDS YP_005172503.1 378772770 11811350 complement(3321867..3322667) 1 NC_016804.1 electron transfer flavoprotein subunit beta 3322667 fixA 11811350 fixA Mycobacterium bovis BCG str. Mexico electron transfer flavoprotein subunit beta YP_005172503.1 3321867 R 717522 CDS YP_005172504.1 378772771 11811351 3322898..3323722 1 NC_016804.1 hypothetical protein 3323722 11811351 BCGMEX_3050 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172504.1 3322898 D 717522 CDS YP_005172505.1 378772772 11811352 3323719..3325299 1 NC_016804.1 hypothetical protein 3325299 11811352 BCGMEX_3051 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172505.1 3323719 D 717522 CDS YP_005172506.1 378772773 11811353 3325331..3326575 1 NC_016804.1 Differs from Rv3032 and Mb3058 by 1aa, P380Q in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transferase 3326575 11811353 BCGMEX_3052 Mycobacterium bovis BCG str. Mexico putative transferase YP_005172506.1 3325331 D 717522 CDS YP_005172507.1 378772774 11811354 3326609..3326998 1 NC_016804.1 hypothetical protein 3326998 11811354 BCGMEX_3053 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172507.1 3326609 D 717522 CDS YP_005172508.1 378772775 11811355 3327177..3327725 1 NC_016804.1 hypothetical protein 3327725 11811355 BCGMEX_3054 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172508.1 3327177 D 717522 CDS YP_005172509.1 378772776 11811356 complement(3327816..3328718) 1 NC_016804.1 putative transferase 3328718 11811356 BCGMEX_3055c Mycobacterium bovis BCG str. Mexico putative transferase YP_005172509.1 3327816 R 717522 CDS YP_005172510.1 378772777 11811357 3329176..3330258 1 NC_016804.1 hypothetical protein 3330258 11811357 BCGMEX_3056 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172510.1 3329176 D 717522 CDS YP_005172511.1 378772778 11811358 complement(3330255..3330938) 1 NC_016804.1 Differs from Mb3062c by 1aa, Q63R in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative secreted protein 3330938 11811358 BCGMEX_3057c Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005172511.1 3330255 R 717522 CDS YP_005172512.1 378772779 11811359 complement(3331011..3332087) 1 NC_016804.1 Differs from Rv3037c by 1aa, A7D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3332087 11811359 BCGMEX_3058c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172512.1 3331011 R 717522 CDS YP_005172513.1 378772780 11811360 complement(3332222..3333205) 1 NC_016804.1 hypothetical protein 3333205 11811360 BCGMEX_3059c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172513.1 3332222 R 717522 CDS YP_005172514.1 378772781 11811361 complement(3333216..3333980) 1 NC_016804.1 Enoyl-CoA hydratase 3333980 echA17 11811361 echA17 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005172514.1 3333216 R 717522 CDS YP_005172515.1 378772782 11811362 complement(3333989..3334855) 1 NC_016804.1 hypothetical protein 3334855 11811362 BCGMEX_3061c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172515.1 3333989 R 717522 CDS YP_005172516.1 378772783 11811363 complement(3334852..3335715) 1 NC_016804.1 ATP-binding protein, ABC transporter 3335715 11811363 BCGMEX_3062c Mycobacterium bovis BCG str. Mexico ATP-binding protein, ABC transporter YP_005172516.1 3334852 R 717522 CDS YP_005172517.1 378772784 11811364 complement(3335730..3336959) 1 NC_016804.1 Differs from Rv3042c by 2aa, S70A, E116G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phosphoserine phosphatase 3336959 serB2 11811364 serB2 Mycobacterium bovis BCG str. Mexico phosphoserine phosphatase YP_005172517.1 3335730 R 717522 CDS YP_005172518.1 378772785 11811365 complement(3336997..3338718) 1 NC_016804.1 putative cytochrome c oxidase polypeptide I 3338718 ctaD 11811365 ctaD Mycobacterium bovis BCG str. Mexico putative cytochrome c oxidase polypeptide I YP_005172518.1 3336997 R 717522 CDS YP_005172519.1 378772786 11811366 3338933..3340012 1 NC_016804.1 putative FeIII-dicitrate-binding periplasmic lipoprotein 3340012 fecB 11811366 fecB Mycobacterium bovis BCG str. Mexico putative FeIII-dicitrate-binding periplasmic lipoprotein YP_005172519.1 3338933 D 717522 CDS YP_005172520.1 378772787 11811367 3340082..3341122 1 NC_016804.1 NADP-dependent alcohol dehydrogenase C 3341122 adhC 11811367 adhC Mycobacterium bovis BCG str. Mexico NADP-dependent alcohol dehydrogenase C YP_005172520.1 3340082 D 717522 CDS YP_005172521.1 378772788 11811368 complement(3341111..3341485) 1 NC_016804.1 hypothetical protein 3341485 11811368 BCGMEX_3067c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172521.1 3341111 R 717522 CDS YP_005172522.1 378772789 11811369 complement(3341819..3342103) 1 NC_016804.1 hypothetical protein 3342103 11811369 BCGMEX_3068c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172522.1 3341819 R 717522 CDS YP_005172523.1 378772790 11811370 complement(3342201..3343175) 1 NC_016804.1 ribonucleoside-diphosphate reductase subunit beta 3343175 nrdF2 11811370 nrdF2 Mycobacterium bovis BCG str. Mexico ribonucleoside-diphosphate reductase subunit beta YP_005172523.1 3342201 R 717522 CDS YP_005172524.1 378772791 11811371 complement(3343306..3344880) 1 NC_016804.1 putative monooxygenase 3344880 11811371 BCGMEX_3070c Mycobacterium bovis BCG str. Mexico putative monooxygenase YP_005172524.1 3343306 R 717522 CDS YP_005172525.1 378772792 11811372 complement(3345014..3345754) 1 NC_016804.1 putative transcriptional regulatory protein, probably AsnC-family 3345754 11811372 BCGMEX_3071c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, probably AsnC-family YP_005172525.1 3345014 R 717522 CDS YP_005172526.1 378772793 11811373 complement(3345882..3347963) 1 NC_016804.1 ribonucleoside-diphosphate reductase subunit alpha 3347963 nrdE 11811373 nrdE Mycobacterium bovis BCG str. Mexico ribonucleoside-diphosphate reductase subunit alpha YP_005172526.1 3345882 R 717522 CDS YP_005172527.1 378772794 11811374 complement(3348029..3348481) 1 NC_016804.1 protein nrdI 3348481 nrdI 11811374 nrdI Mycobacterium bovis BCG str. Mexico protein nrdI YP_005172527.1 3348029 R 717522 CDS YP_005172528.1 378772795 11811375 complement(3348516..3348755) 1 NC_016804.1 putative glutaredoxin electron transport component of nrdEF 3348755 nrdH 11811375 nrdH Mycobacterium bovis BCG str. Mexico putative glutaredoxin electron transport component of nrdEF YP_005172528.1 3348516 R 717522 CDS YP_005172529.1 378772796 11811376 complement(3348733..3349101) 1 NC_016804.1 hypothetical protein 3349101 11811376 BCGMEX_3075c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172529.1 3348733 R 717522 CDS YP_005172530.1 378772797 11811377 complement(3349218..3349772) 1 NC_016804.1 hypothetical protein 3349772 11811377 BCGMEX_3076c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172530.1 3349218 R 717522 CDS YP_005172531.1 378772798 11811378 3349864..3350478 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3350478 11811378 BCGMEX_3077 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172531.1 3349864 D 717522 CDS YP_005172532.1 378772799 11811379 3350488..3351528 1 NC_016804.1 DNA polymerase IV 3351528 dinP 11811379 dinP Mycobacterium bovis BCG str. Mexico DNA polymerase IV YP_005172532.1 3350488 D 717522 CDS YP_005172533.1 378772800 11811380 complement(3351582..3352445) 1 NC_016804.1 short-chain dehydrogenase 3352445 11811380 BCGMEX_3079c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005172533.1 3351582 R 717522 CDS YP_005172534.1 378772801 11811381 complement(3352509..3353159) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3353159 11811381 BCGMEX_3080c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172534.1 3352509 R 717522 CDS YP_005172535.1 378772802 11811382 3353275..3354753 1 NC_016804.1 Differs from Mb3085 by 1aa, E44K and Rv3059 by 2aa, E44K, G445D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytochrome P450 136 3354753 cyp136 11811382 cyp136 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 136 YP_005172535.1 3353275 D 717522 CDS YP_005172536.1 378772803 11811383 complement(3355524..3356996) 1 NC_016804.1 putative transcriptional regulatory protein, GntR family 3356996 11811383 BCGMEX_3082c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, GntR family YP_005172536.1 3355524 R 717522 CDS YP_005172537.1 378772804 11811384 complement(3357113..3359278) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium tuberculosis strain H37Rv, fadE22 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion splits fadE22 into 2 parts, fadE22a and fadE22b. Differs from Mb3087c and from Rv3061c by 2aa, E488K, C497S in BCG Pasteur, BCG Tokyo and BCG Mexico; acyl-CoA dehydrogenase, short-chain specific 3359278 fadE22 11811384 fadE22 Mycobacterium bovis BCG str. Mexico acyl-CoA dehydrogenase, short-chain specific YP_005172537.1 3357113 R 717522 CDS YP_005172538.1 378772805 11811385 3359435..3360958 1 NC_016804.1 Differs from Rv3062 by 1aa, S91P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ATP-dependent DNA ligase 3360958 ligB 11811385 ligB Mycobacterium bovis BCG str. Mexico ATP-dependent DNA ligase YP_005172538.1 3359435 D 717522 CDS YP_005172539.1 378772806 11811386 3361094..3363370 1 NC_016804.1 Differs from Rv3063 by 3aa, C402G, S559R, P600L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative carbon starvation protein A 3363370 cstA 11811386 cstA Mycobacterium bovis BCG str. Mexico putative carbon starvation protein A YP_005172539.1 3361094 D 717522 CDS YP_005172540.1 378772807 11811387 complement(3363676..3364101) 1 NC_016804.1 putative integral membrane protein 3364101 11811387 BCGMEX_3086c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172540.1 3363676 R 717522 CDS YP_005172541.1 378772808 11811388 3364238..3364561 1 NC_016804.1 multidrug resistance protein 3364561 mmr 11811388 mmr Mycobacterium bovis BCG str. Mexico multidrug resistance protein YP_005172541.1 3364238 D 717522 CDS YP_005172542.1 378772809 11811389 3364558..3365166 1 NC_016804.1 putative transcriptional regulatory protein 3365166 11811389 BCGMEX_3088 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172542.1 3364558 D 717522 CDS YP_005172543.1 378772810 11811390 3365279..3365689 1 NC_016804.1 Differs from Rv3067 and Mb3094 by 1aa A3T in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3365689 11811390 BCGMEX_3089 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172543.1 3365279 D 717522 CDS YP_005172544.1 378772811 11811392 complement(3365830..3367473) 1 NC_016804.1 phosphoglucomutase 3367473 pgmA 11811392 pgmA Mycobacterium bovis BCG str. Mexico phosphoglucomutase YP_005172544.1 3365830 R 717522 CDS YP_005172545.1 378772812 11811393 3367543..3367941 1 NC_016804.1 protein crcB-like protein 1 3367941 crcB1 11811393 crcB1 Mycobacterium bovis BCG str. Mexico protein crcB-like protein 1 YP_005172545.1 3367543 D 717522 CDS YP_005172546.1 378772813 11811394 3367938..3368318 1 NC_016804.1 protein crcB-like protein 2 3368318 crcB2 11811394 crcB2 Mycobacterium bovis BCG str. Mexico protein crcB-like protein 2 YP_005172546.1 3367938 D 717522 CDS YP_005172547.1 378772814 11811395 3368315..3369424 1 NC_016804.1 hypothetical protein 3369424 11811395 BCGMEX_3093 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172547.1 3368315 D 717522 CDS YP_005172548.1 378772815 11811396 complement(3369649..3370173) 1 NC_016804.1 hypothetical protein 3370173 11811396 BCGMEX_3094c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172548.1 3369649 R 717522 CDS YP_005172549.1 378772816 11811397 complement(3370180..3370536) 1 NC_016804.1 hypothetical protein 3370536 11811397 BCGMEX_3095c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172549.1 3370180 R 717522 CDS YP_005172550.1 378772817 11811398 3370630..3371904 1 NC_016804.1 hypothetical protein 3371904 11811398 BCGMEX_3096 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172550.1 3370630 D 717522 CDS YP_005172551.1 378772818 11811399 complement(3371901..3372824) 1 NC_016804.1 hypothetical protein 3372824 11811399 BCGMEX_3097c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172551.1 3371901 R 717522 CDS YP_005172552.1 378772819 11811401 3372923..3373399 1 NC_016804.1 hypothetical protein 3373399 11811401 BCGMEX_3098 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172552.1 3372923 D 717522 CDS YP_005172553.1 378772820 11811402 3373392..3375203 1 NC_016804.1 Differs from Rv3077 by 1aa R311G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative hydrolase 3375203 11811402 BCGMEX_3099 Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005172553.1 3373392 D 717522 CDS YP_005172554.1 378772821 11811403 3375204..3375605 1 NC_016804.1 putative hydroxylaminobenzene mutase 3375605 hab 11811403 hab Mycobacterium bovis BCG str. Mexico putative hydroxylaminobenzene mutase YP_005172554.1 3375204 D 717522 CDS YP_005172555.1 378772822 11811404 complement(3375621..3376448) 1 NC_016804.1 hypothetical protein 3376448 11811404 BCGMEX_3101c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172555.1 3375621 R 717522 CDS YP_005172556.1 378772823 11811405 complement(3376507..3379839) 1 NC_016804.1 Differs from Rv3080c by 1aa, V217A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative serine/threonine-protein kinase 3379839 pknK 11811405 pknK Mycobacterium bovis BCG str. Mexico putative serine/threonine-protein kinase YP_005172556.1 3376507 R 717522 CDS YP_005172557.1 378772824 11811406 3379891..3381129 1 NC_016804.1 Differs from Rv3081 and Mb3108 by 1aa, A108V in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3381129 11811406 BCGMEX_3103 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172557.1 3379891 D 717522 CDS YP_005172558.1 378772825 11811407 complement(3381255..3382277) 1 NC_016804.1 Differs from Rv3082c by 1aa, C322R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative virulence-regulating 38 kDa protein 3382277 virS 11811407 virS Mycobacterium bovis BCG str. Mexico putative virulence-regulating 38 kDa protein YP_005172558.1 3381255 R 717522 CDS YP_005172559.1 378772826 11811408 3382355..3383842 1 NC_016804.1 Differs from Mb3110 by 1aa, S81I and from Rv3083 by 2aa, S81I, I94V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative monooxygenase 3383842 11811408 BCGMEX_3105 Mycobacterium bovis BCG str. Mexico putative monooxygenase YP_005172559.1 3382355 D 717522 CDS YP_005172560.1 378772827 11811409 3383848..3384774 1 NC_016804.1 Differs from Rv3084 and Mb3111 by 1aa, G276S in BCG Pasteur, BCG Tokyo and BCG Mexico; putative acetyl-hydrolase/esterase 3384774 lipR 11811409 lipR Mycobacterium bovis BCG str. Mexico putative acetyl-hydrolase/esterase YP_005172560.1 3383848 D 717522 CDS YP_005172561.1 378772828 11811410 3384771..3385601 1 NC_016804.1 putative short-chain dehydrogenase/reductase family 3385601 11811410 BCGMEX_3107 Mycobacterium bovis BCG str. Mexico putative short-chain dehydrogenase/reductase family YP_005172561.1 3384771 D 717522 CDS YP_005172562.1 378772829 11811411 3385632..3386738 1 NC_016804.1 putative zinc-type alcohol dehydrogenase 3386738 adhD 11811411 adhD Mycobacterium bovis BCG str. Mexico putative zinc-type alcohol dehydrogenase YP_005172562.1 3385632 D 717522 CDS YP_005172563.1 378772830 11811412 3386776..3388194 1 NC_016804.1 Differs from Rv3087 by 1aa, V447L, and from Mb3114 by 1aa, T158A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative diacylglycerol O-acyltransferase 3388194 11811412 BCGMEX_3109 Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005172563.1 3386776 D 717522 CDS YP_005172564.1 378772831 11811413 3388191..3389615 1 NC_016804.1 putative diacylglycerol O-acyltransferase 3389615 tgs4 11811413 tgs4 Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005172564.1 3388191 D 717522 CDS YP_005172565.1 378772832 11811414 3389612..3391123 1 NC_016804.1 putative chain-fatty-acid-CoA ligase 3391123 fadD13 11811414 fadD13 Mycobacterium bovis BCG str. Mexico putative chain-fatty-acid-CoA ligase YP_005172565.1 3389612 D 717522 CDS YP_005172566.1 378772833 11811415 3392062..3392949 1 NC_016804.1 hypothetical protein 3392949 11811415 BCGMEX_3112 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172566.1 3392062 D 717522 CDS YP_005172567.1 378772834 11811416 3392967..3394658 1 NC_016804.1 hypothetical protein 3394658 11811416 BCGMEX_3113 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172567.1 3392967 D 717522 CDS YP_005172568.1 378772835 11811417 complement(3394665..3395585) 1 NC_016804.1 Differs from Mb3119c by 1 aa, I237M in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 3395585 11811417 BCGMEX_3114c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172568.1 3394665 R 717522 CDS YP_005172569.1 378772836 11811418 complement(3395611..3396615) 1 NC_016804.1 Differs from Rv3093c by 1aa W210C in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 3396615 11811418 BCGMEX_3115c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172569.1 3395611 R 717522 CDS YP_005172570.1 378772837 11811419 complement(3396612..3397742) 1 NC_016804.1 hypothetical protein 3397742 11811419 BCGMEX_3116c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172570.1 3396612 R 717522 CDS YP_005172571.1 378772838 11811420 3397824..3398300 1 NC_016804.1 transcriptional regulatory protein 3398300 11811420 BCGMEX_3117 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein YP_005172571.1 3397824 D 717522 CDS YP_005172572.1 378772839 11811421 3398398..3399537 1 NC_016804.1 Differs from Rv3097 by 1aa G28E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3399537 11811421 BCGMEX_3118 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172572.1 3398398 D 717522 CDS YP_005172573.1 378772840 11811422 complement(3399629..3400942) 1 NC_016804.1 Differs from Rv3097c by 1aa A58G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE-PGRS family protein 3400942 PE_PGRS63 11811422 PE_PGRS63 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005172573.1 3399629 R 717522 CDS YP_005172574.1 378772841 11811423 complement(3401061..3401513) 1 NC_016804.1 Differs from Rv3098c by 1aa E117D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3401513 11811423 BCGMEX_3120c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172574.1 3401061 R 717522 CDS YP_005172575.1 378772842 11811425 complement(3402264..3403115) 1 NC_016804.1 hypothetical protein 3403115 11811425 BCGMEX_3121c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172575.1 3402264 R 717522 CDS YP_005172576.1 378772843 11811426 complement(3403152..3403634) 1 NC_016804.1 SsrA-binding protein 3403634 smpB 11811426 smpB Mycobacterium bovis BCG str. Mexico SsrA-binding protein YP_005172576.1 3403152 R 717522 CDS YP_005172577.1 378772844 11811427 complement(3403637..3404530) 1 NC_016804.1 Differs from Rv3101c by 1aa, S171N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; cell division protein 3404530 ftsX 11811427 ftsX Mycobacterium bovis BCG str. Mexico cell division protein YP_005172577.1 3403637 R 717522 CDS YP_005172578.1 378772845 11811428 complement(3404531..3405220) 1 NC_016804.1 cell division ATP-binding protein 3405220 ftsE 11811428 ftsE Mycobacterium bovis BCG str. Mexico cell division ATP-binding protein YP_005172578.1 3404531 R 717522 CDS YP_005172579.1 378772846 11811429 complement(3405264..3405701) 1 NC_016804.1 hypothetical protein 3405701 11811429 BCGMEX_3125c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172579.1 3405264 R 717522 CDS YP_005172580.1 378772847 11811430 complement(3405703..3406629) 1 NC_016804.1 putative transmembrane protein 3406629 11811430 BCGMEX_3126c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172580.1 3405703 R 717522 CDS YP_005172581.1 378772848 11811431 complement(3406619..3407755) 1 NC_016804.1 peptide chain release factor 2 3407755 prfB 11811431 prfB Mycobacterium bovis BCG str. Mexico peptide chain release factor 2 YP_005172581.1 3406619 R 717522 CDS YP_005172582.1 378772849 11811432 3407859..3409229 1 NC_016804.1 Differs from Rv3106 by 2aa, I141V, D385N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; NADPH-ferredoxin reductase 3409229 fprA 11811432 fprA Mycobacterium bovis BCG str. Mexico NADPH-ferredoxin reductase YP_005172582.1 3407859 D 717522 CDS YP_005172583.1 378772850 11811434 complement(3409230..3410813) 1 NC_016804.1 alkyldihydroxyacetonephosphate synthase 3410813 agpS 11811434 agpS Mycobacterium bovis BCG str. Mexico alkyldihydroxyacetonephosphate synthase YP_005172583.1 3409230 R 717522 CDS YP_005172584.1 378772851 11811435 3410912..3411352 1 NC_016804.1 Differs from Mb3135 by 1aa I145V in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3411352 11811435 BCGMEX_3130 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172584.1 3410912 D 717522 CDS YP_005172585.1 378772852 11811436 3411501..3412580 1 NC_016804.1 Differs from Mb3136 by 1aa, T324A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; molybdenum cofactor biosynthesis protein A 3412580 moaA1 11811436 moaA1 Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein A YP_005172585.1 3411501 D 717522 CDS YP_005172586.1 378772853 11811437 3412631..3413026 1 NC_016804.1 Pterin-4-alpha-carbinolamine dehydratase 3413026 moaB1 11811437 moaB1 Mycobacterium bovis BCG str. Mexico Pterin-4-alpha-carbinolamine dehydratase YP_005172586.1 3412631 D 717522 CDS YP_005172587.1 378772854 11811438 3413023..3413535 1 NC_016804.1 molybdenum cofactor biosynthesis protein C 3413535 moaC 11811438 moaC Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein C YP_005172587.1 3413023 D 717522 CDS YP_005172588.1 378772855 11811439 3413552..3413803 1 NC_016804.1 molybdenum cofactor biosynthesis protein D 3413803 moaD1 11811439 moaD1 Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein D YP_005172588.1 3413552 D 717522 CDS YP_005172589.1 378772856 11811440 3413925..3414593 1 NC_016804.1 Differs from Rv3113 by 3aa, C11W, E134G, R191L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative phosphatase 3414593 11811440 BCGMEX_3135 Mycobacterium bovis BCG str. Mexico putative phosphatase YP_005172589.1 3413925 D 717522 CDS YP_005172590.1 378772857 11811441 3414610..3415140 1 NC_016804.1 Differs from Rv3114 by 1aa, P11S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3415140 11811441 BCGMEX_3136 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172590.1 3414610 D 717522 CDS YP_005172591.1 378772858 11811442 3415302..3416549 1 NC_016804.1 putative transposase 3416549 11811442 BCGMEX_3137 Mycobacterium bovis BCG str. Mexico putative transposase YP_005172591.1 3415302 D 717522 CDS YP_005172592.1 378772859 11811443 3416627..3417796 1 NC_016804.1 putative molybdenum cofactor biosynthesis protein 3417796 moeB2 11811443 moeB2 Mycobacterium bovis BCG str. Mexico putative molybdenum cofactor biosynthesis protein YP_005172592.1 3416627 D 717522 CDS YP_005172593.1 378772860 11811444 3417825..3418787 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokio, BCG Mexico and Mycobacterium bovis, a large deletion of 2775 bp (RD12) leads to the loss of the COOH part of cysA3, the following CDSs, sseC1, moaE1, Rv3120 and a large part of cyp141 except the COOH end, compared to the homolog in Mycobacterium tuberculosis strain H37Rv; thiosulfate sulfurtransferase 3418787 cysA3 11811444 cysA3 Mycobacterium bovis BCG str. Mexico thiosulfate sulfurtransferase YP_005172593.1 3417825 D 717522 CDS YP_005172594.1 378772861 11811445 3419165..3419635 1 NC_016804.1 Differs from Rv3122 by 1aa, S156R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3419635 11811445 BCGMEX_3140 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172594.1 3419165 D 717522 CDS YP_005172595.1 378772862 11811446 3419645..3420139 1 NC_016804.1 Differs from Rv3123 by 1aa, Q40R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3420139 11811446 BCGMEX_3141 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172595.1 3419645 D 717522 CDS YP_005172596.1 378772863 11811447 3420582..3421451 1 NC_016804.1 Differs from Rv3124 and Mb3147 by 1aa, G159E in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein 3421451 11811447 BCGMEX_3142 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172596.1 3420582 D 717522 CDS YP_005172597.1 378772864 11811448 complement(3421552..3421866) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, PPE49 has incurred a single base deletion in codon 272 compared to Rv3125c and Mb3148c leading to frameshift, and two products of 282 and 104 aa, compared to 391 in others; PPE family protein 3421866 PPE49b 11811448 PPE49b Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172597.1 3421552 R 717522 CDS YP_005172598.1 378772865 11811449 complement(3421878..3422726) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, PPE49 has incurred a single base deletion in codon 272 compared to Rv3125c and Mb3148c leading to frameshift, and two products of 282 and 104 aa, compared to 391 in others. Differs from Rv3125c by 1aa, V38A; PPE family protein 3422726 PPE49a 11811449 PPE49a Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172598.1 3421878 R 717522 CDS YP_005172599.1 378772866 11811450 complement(3422883..3423197) 1 NC_016804.1 hypothetical protein 3423197 11811450 BCGMEX_3145c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172599.1 3422883 R 717522 CDS YP_005172600.1 378772867 11811451 3423222..3424256 1 NC_016804.1 Differs from Rv3127 by 1aa, C95F in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3424256 11811451 BCGMEX_3146 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172600.1 3423222 D 717522 CDS YP_005172601.1 378772868 11811452 complement(3424243..3424593) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv3128c exists as a single gene with an in-frame amber stop codon. In Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico, Rv3128c is split into 2, Mb3151c and Mb3152c; hypothetical protein 3424593 11811452 BCGMEX_3147c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172601.1 3424243 R 717522 CDS YP_005172602.1 378772869 11811453 complement(3424675..3425256) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv3128c exists as a single gene with an in-frame amber stop codon. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, Rv3128c is split into 2 genes. Differs from Mb3152c by 1aa, V166G in BCG Pasteur and BCG Tokyo; hypothetical protein 3425256 11811453 BCGMEX_3148c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172602.1 3424675 R 717522 CDS YP_005172603.1 378772870 11811454 3425735..3426067 1 NC_016804.1 hypothetical protein 3426067 11811454 BCGMEX_3149 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172603.1 3425735 D 717522 CDS YP_005172604.1 378772871 11811455 complement(3426050..3427441) 1 NC_016804.1 putative diacylglycerol O-acyltransferase 3427441 11811455 BCGMEX_3150c Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005172604.1 3426050 R 717522 CDS YP_005172605.1 378772872 11811456 3427626..3428624 1 NC_016804.1 putative NAD(P)H nitroreductase 3428624 11811456 BCGMEX_3151 Mycobacterium bovis BCG str. Mexico putative NAD(P)H nitroreductase YP_005172605.1 3427626 D 717522 CDS YP_005172606.1 378772873 11811457 complement(3428604..3430340) 1 NC_016804.1 Differs from Rv3132c by 1aa, T283I in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; two component sensor histidine kinase 3430340 devS 11811457 devS Mycobacterium bovis BCG str. Mexico two component sensor histidine kinase YP_005172606.1 3428604 R 717522 CDS YP_005172607.1 378772874 11811458 complement(3430337..3430990) 1 NC_016804.1 Two component transcriptional regulatory protein 3430990 devR 11811458 devR Mycobacterium bovis BCG str. Mexico Two component transcriptional regulatory protein YP_005172607.1 3430337 R 717522 CDS YP_005172608.1 378772875 11811459 complement(3431018..3431824) 1 NC_016804.1 Universal stress protein 3431824 11811459 BCGMEX_3154c Mycobacterium bovis BCG str. Mexico Universal stress protein YP_005172608.1 3431018 R 717522 CDS YP_005172609.1 378772876 11811460 3432409..3433554 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a large 1337 bp insertion (I-RD08) leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (381 aa versus 132 aa). Differs from Mb3159 by 1aa, K213E in BCG Pasteur and BCG Mexico. Differ from Mb3159 by 1aa, G256E in BCG Tokyo; PPE family protein 3433554 PPE50 11811460 PPE50 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172609.1 3432409 D 717522 CDS YP_005172610.1 378772877 11811461 3434206..3435348 1 NC_016804.1 PPE family protein 3435348 PPE51 11811461 PPE51 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172610.1 3434206 D 717522 CDS YP_005172611.1 378772878 11811462 3435805..3436587 1 NC_016804.1 Differs from Rv3137 by 1aa, L168P in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative monophosphatase 3436587 11811462 BCGMEX_3157 Mycobacterium bovis BCG str. Mexico putative monophosphatase YP_005172611.1 3435805 D 717522 CDS YP_005172612.1 378772879 11811463 3436607..3437695 1 NC_016804.1 Differs from Rv3138 by 2aa, N110S, P271T, and from Mb3162 by 2aa, F257S, P270L in BCG Pasteur, BCG Tokyo and BCG Mexico; putative pyruvate-formate lyase-activating enzyme 3437695 pflA 11811463 pflA Mycobacterium bovis BCG str. Mexico putative pyruvate-formate lyase-activating enzyme YP_005172612.1 3436607 D 717522 CDS YP_005172613.1 378772880 11811464 3437775..3439181 1 NC_016804.1 putative acyl-CoA dehydrogenase 3439181 fadE24 11811464 fadE24 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005172613.1 3437775 D 717522 CDS YP_005172614.1 378772881 11811465 3439202..3440407 1 NC_016804.1 putative acyl-CoA dehydrogenase 3440407 fadE23 11811465 fadE23 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005172614.1 3439202 D 717522 CDS YP_005172615.1 378772882 11811466 3440507..3441478 1 NC_016804.1 putative NADPH quinone oxidoreductase 3441478 fadB4 11811466 fadB4 Mycobacterium bovis BCG str. Mexico putative NADPH quinone oxidoreductase YP_005172615.1 3440507 D 717522 CDS YP_005172616.1 378772883 11811467 complement(3441530..3441958) 1 NC_016804.1 Differs from Mb3166c by 1aa, H133Q in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3441958 11811467 BCGMEX_3162c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172616.1 3441530 R 717522 CDS YP_005172617.1 378772884 11811468 3442066..3442467 1 NC_016804.1 putative response regulator 3442467 11811468 BCGMEX_3163 Mycobacterium bovis BCG str. Mexico putative response regulator YP_005172617.1 3442066 D 717522 CDS YP_005172618.1 378772885 11811469 complement(3442500..3443729) 1 NC_016804.1 Differs from Rv3144c by 1aa, G226S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3443729 PPE52 11811469 PPE52 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172618.1 3442500 R 717522 CDS YP_005172619.1 378772886 11811470 3444094..3444480 1 NC_016804.1 NADH-quinone oxidoreductase subunit A 3444480 nuoA 11811470 nuoA Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit A YP_005172619.1 3444094 D 717522 CDS YP_005172620.1 378772887 11811471 3444489..3445043 1 NC_016804.1 NADH-quinone oxidoreductase subunit B 3445043 nuoB 11811471 nuoB Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit B YP_005172620.1 3444489 D 717522 CDS YP_005172621.1 378772888 11811472 3445040..3445750 1 NC_016804.1 NADH-quinone oxidoreductase subunit C 3445750 nuoC 11811472 nuoC Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit C YP_005172621.1 3445040 D 717522 CDS YP_005172622.1 378772889 11811473 3445750..3447072 1 NC_016804.1 NADH-quinone oxidoreductase subunit D 3447072 nuoD 11811473 nuoD Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit D YP_005172622.1 3445750 D 717522 CDS YP_005172623.1 378772890 11811474 3447069..3447827 1 NC_016804.1 NADH-quinone oxidoreductase subunit E 3447827 nuoE 11811474 nuoE Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit E YP_005172623.1 3447069 D 717522 CDS YP_005172624.1 378772891 11811475 3447824..3449161 1 NC_016804.1 NADH-quinone oxidoreductase subunit F 3449161 nuoF 11811475 nuoF Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit F YP_005172624.1 3447824 D 717522 CDS YP_005172625.1 378772892 11811476 3449158..3451578 1 NC_016804.1 NADH-quinone oxidoreductase subunit G 3451578 nuoG 11811476 nuoG Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit G YP_005172625.1 3449158 D 717522 CDS YP_005172626.1 378772893 11811477 3451694..3452926 1 NC_016804.1 NADH-ubiquinone oxidoreductase subunit H 3452926 nuoH 11811477 nuoH Mycobacterium bovis BCG str. Mexico NADH-ubiquinone oxidoreductase subunit H YP_005172626.1 3451694 D 717522 CDS YP_005172627.1 378772894 11811478 3452919..3453554 1 NC_016804.1 Differs from Rv3153 by 1aa, A180T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; NADH-quinone oxidoreductase subunit I 3453554 nuoI 11811478 nuoI Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit I YP_005172627.1 3452919 D 717522 CDS YP_005172628.1 378772895 11811479 3453551..3454339 1 NC_016804.1 NADH dehydrogenase subunit J 3454339 nuoJ 11811479 nuoJ Mycobacterium bovis BCG str. Mexico NADH dehydrogenase subunit J YP_005172628.1 3453551 D 717522 CDS YP_005172629.1 378772896 11811480 3454336..3454635 1 NC_016804.1 NADH-quinone oxidoreductase subunit K 3454635 nuoK 11811480 nuoK Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit K YP_005172629.1 3454336 D 717522 CDS YP_005172630.1 378772897 11811481 3454646..3456547 1 NC_016804.1 Differs from Mb3180 by 1aa F297Y in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; NADH-quinone oxidoreductase subunit L 3456547 nuoL 11811481 nuoL Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit L YP_005172630.1 3454646 D 717522 CDS YP_005172631.1 378772898 11811482 3456544..3458205 1 NC_016804.1 Differs from Rv3157 by 1aa, I476V, and from Mb3181 by 1aa, G395D in BCG Pasteur, BCG Tokyo and BCG Mexico; NADH-quinone oxidoreductase subunit M 3458205 nuoM 11811482 nuoM Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit M YP_005172631.1 3456544 D 717522 CDS YP_005172632.1 378772899 11811483 3458202..3459797 1 NC_016804.1 NADH-quinone oxidoreductase subunit N 3459797 nuoN 11811483 nuoN Mycobacterium bovis BCG str. Mexico NADH-quinone oxidoreductase subunit N YP_005172632.1 3458202 D 717522 CDS YP_005172633.1 378772900 11811484 complement(3459803..3461572) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, albeit a 2146 bp insertion occurs overlapping the NH2-terminal part, this leads to an Equivalent product, compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Differs from Rv3159c by 2aa, deletion of A64, V87A, and from Mb3183c by 1aa, V87A in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3461572 PPE53 11811484 PPE53 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172633.1 3459803 R 717522 CDS YP_005172634.1 378772901 11811485 complement(3461820..3463721) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, an insertion of 2146 bp exists between PPE53 and Rv3160c compared to Mycobacterium tuberculosis strain H37Rv. This leads to an additional gene, PPE70 Equivalent to MT3248 from Mycobacterium tuberculosis strain CDC1551. Differs from Mb3184c by 1aa, addition of A64 in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3463721 PPE70 11811485 PPE70 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172634.1 3461820 R 717522 CDS YP_005172635.1 378772902 11811486 complement(3463896..3464537) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3464537 11811486 BCGMEX_3181c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172635.1 3463896 R 717522 CDS YP_005172636.1 378772903 11811487 complement(3464548..3465696) 1 NC_016804.1 Differs from Rv3161c by 1aa, L62V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative dioxygenase 3465696 11811487 BCGMEX_3182c Mycobacterium bovis BCG str. Mexico putative dioxygenase YP_005172636.1 3464548 R 717522 CDS YP_005172637.1 378772904 11811488 complement(3465612..3466202) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion, leads to a longer product with different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; putative integral membrane protein 3466202 11811488 BCGMEX_3183c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172637.1 3465612 R 717522 CDS YP_005172638.1 378772905 11811489 complement(3466199..3467470) 1 NC_016804.1 Differs from Mb3188c by 1aa, D341E in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative secreted protein 3467470 11811489 BCGMEX_3184c Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005172638.1 3466199 R 717522 CDS YP_005172639.1 378772906 11811490 complement(3467500..3468462) 1 NC_016804.1 Differs from Mb3189c by 1aa, E20G in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; methanol dehydrogenase transcriptional regulatory protein 3468462 moxR3 11811490 moxR3 Mycobacterium bovis BCG str. Mexico methanol dehydrogenase transcriptional regulatory protein YP_005172639.1 3467500 R 717522 CDS YP_005172640.1 378772907 11811491 complement(3468470..3468952) 1 NC_016804.1 hypothetical protein 3468952 11811491 BCGMEX_3186c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172640.1 3468470 R 717522 CDS YP_005172641.1 378772908 11811492 complement(3468949..3469908) 1 NC_016804.1 Differs from Rv3166c and Mb3191c by 1aa, A202S in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3469908 11811492 BCGMEX_3187c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172641.1 3468949 R 717522 CDS YP_005172642.1 378772909 11811493 complement(3469988..3470614) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3470614 11811493 BCGMEX_3188c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172642.1 3469988 R 717522 CDS YP_005172643.1 378772910 11811494 3470659..3471795 1 NC_016804.1 Differs from Mb3193 by 1aa, W65R in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3471795 11811494 BCGMEX_3189 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172643.1 3470659 D 717522 CDS YP_005172644.1 378772911 11811495 3471795..3472919 1 NC_016804.1 hypothetical protein 3472919 11811495 BCGMEX_3190 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172644.1 3471795 D 717522 CDS YP_005172645.1 378772912 11811496 3473062..3474408 1 NC_016804.1 putative flavin-containing monoamine oxidase 3474408 aofH 11811496 aofH Mycobacterium bovis BCG str. Mexico putative flavin-containing monoamine oxidase YP_005172645.1 3473062 D 717522 CDS YP_005172646.1 378772913 11811497 complement(3474403..3475302) 1 NC_016804.1 putative non-heme haloperoxidase 3475302 hpx 11811497 hpx Mycobacterium bovis BCG str. Mexico putative non-heme haloperoxidase YP_005172646.1 3474403 R 717522 CDS YP_005172647.1 378772914 11811498 complement(3475439..3475921) 1 NC_016804.1 hypothetical protein 3475921 11811498 BCGMEX_3193c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172647.1 3475439 R 717522 CDS YP_005172648.1 378772915 11811499 complement(3476000..3476602) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3476602 11811499 BCGMEX_3194c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172648.1 3476000 R 717522 CDS YP_005172649.1 378772916 11811500 3476695..3477402 1 NC_016804.1 Differs from Rv3174 by 1aa, A9V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative short chain dehydrogenase 3477402 11811500 BCGMEX_3195 Mycobacterium bovis BCG str. Mexico putative short chain dehydrogenase YP_005172649.1 3476695 D 717522 CDS YP_005172650.1 378772917 11811501 3477417..3478904 1 NC_016804.1 amidase 3478904 11811501 BCGMEX_3196 Mycobacterium bovis BCG str. Mexico amidase YP_005172650.1 3477417 D 717522 CDS YP_005172651.1 378772918 11811502 complement(3478901..3479218) 1 NC_016804.1 n Mycobacterium tuberculosis strain H37Rv, mesT exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion splits mesT into 2 parts, mesTa and mesTb.; putative epoxide hydrolase 3479218 mesTb 11811502 mesTb Mycobacterium bovis BCG str. Mexico putative epoxide hydrolase YP_005172651.1 3478901 R 717522 CDS YP_005172652.1 378772919 11811503 complement(3479230..3479856) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, mesT exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion splits mesT into 2 parts, mesTa and mesTb; putative epoxide hydrolase 3479856 mesTa 11811503 mesTa Mycobacterium bovis BCG str. Mexico putative epoxide hydrolase YP_005172652.1 3479230 R 717522 CDS YP_005172653.1 378772920 11811504 3480003..3480863 1 NC_016804.1 putative peroxidase 3480863 11811504 BCGMEX_3199 Mycobacterium bovis BCG str. Mexico putative peroxidase YP_005172653.1 3480003 D 717522 CDS YP_005172654.1 378772921 11811505 3480994..3481353 1 NC_016804.1 hypothetical protein 3481353 11811505 BCGMEX_3200 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172654.1 3480994 D 717522 CDS YP_005172655.1 378772922 11811506 3481593..3481886 1 NC_016804.1 hypothetical protein 3481886 11811506 BCGMEX_3201 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172655.1 3481593 D 717522 CDS YP_005172656.1 378772923 11811507 3482174..3483463 1 NC_016804.1 hypothetical protein 3483463 11811507 BCGMEX_3202 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172656.1 3482174 D 717522 CDS YP_005172657.1 378772924 11811508 complement(3483810..3484244) 1 NC_016804.1 hypothetical protein 3484244 11811508 BCGMEX_3203c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172657.1 3483810 R 717522 CDS YP_005172658.1 378772925 11811509 complement(3484247..3484699) 1 NC_016804.1 hypothetical protein 3484699 11811509 BCGMEX_3204c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172658.1 3484247 R 717522 CDS YP_005172659.1 378772926 11811510 3484930..3485274 1 NC_016804.1 hypothetical protein 3485274 11811510 BCGMEX_3205 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172659.1 3484930 D 717522 CDS YP_005172660.1 378772927 11811511 3485271..3485600 1 NC_016804.1 putative transcriptional regulatory protein 3485600 11811511 BCGMEX_3206 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172660.1 3485271 D 717522 CDS YP_005172661.1 378772928 11811512 3486138..3486485 1 NC_016804.1 hypothetical protein 3486485 11811512 BCGMEX_3207 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172661.1 3486138 D 717522 CDS YP_005172662.1 378772929 11811513 3486482..3487102 1 NC_016804.1 hypothetical protein 3487102 11811513 BCGMEX_3208 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172662.1 3486482 D 717522 CDS YP_005172663.1 378772930 11811514 complement(3487262..3488527) 1 NC_016804.1 Differs from Rv3190c by 2aa, P138L, A330V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3488527 11811514 BCGMEX_3209c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172663.1 3487262 R 717522 CDS YP_005172664.1 378772931 11811515 complement(3489151..3490185) 1 NC_016804.1 putative transposase 3490185 11811515 BCGMEX_3210c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172664.1 3489151 R 717522 CDS YP_005172665.1 378772932 11811517 3491400..3491861 1 NC_016804.1 hypothetical protein 3491861 11811517 BCGMEX_3211 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172665.1 3491400 D 717522 CDS YP_005172666.1 378772933 11811518 complement(3492031..3495009) 1 NC_016804.1 Differs from Rv3193c by 2aa, E356Q, Q843R, and from Mb3215c by 1aa, E356Q in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3495009 11811518 BCGMEX_3212c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172666.1 3492031 R 717522 CDS YP_005172667.1 378772934 11811519 complement(3495101..3496123) 1 NC_016804.1 putative secreted protein 3496123 11811519 BCGMEX_3213c Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005172667.1 3495101 R 717522 CDS YP_005172668.1 378772935 11811520 3496201..3497619 1 NC_016804.1 hypothetical protein 3497619 11811520 BCGMEX_3214 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172668.1 3496201 D 717522 CDS YP_005172669.1 378772936 11811521 3497625..3498524 1 NC_016804.1 hypothetical protein 3498524 11811521 BCGMEX_3215 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172669.1 3497625 D 717522 CDS YP_005172670.1 378772937 11811522 complement(3498533..3498733) 1 NC_016804.1 hypothetical protein 3498733 11811522 BCGMEX_3216c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172670.1 3498533 R 717522 CDS YP_005172671.1 378772938 11811523 3498871..3500214 1 NC_016804.1 putative ATP-binding protein ABC transporter 3500214 11811523 BCGMEX_3217 Mycobacterium bovis BCG str. Mexico putative ATP-binding protein ABC transporter YP_005172671.1 3498871 D 717522 CDS YP_005172672.1 378772939 11811524 complement(3500248..3500526) 1 NC_016804.1 putative transcriptional regulatory protein whiB-like protein 3500526 whiB7 11811524 whiB7 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein whiB-like protein YP_005172672.1 3500248 R 717522 CDS YP_005172673.1 378772940 11811526 complement(3500956..3503058) 1 NC_016804.1 putative DNA helicase II-like protein 3503058 uvrD2 11811526 uvrD2 Mycobacterium bovis BCG str. Mexico putative DNA helicase II-like protein YP_005172673.1 3500956 R 717522 CDS YP_005172674.1 378772941 11811527 3503182..3503436 1 NC_016804.1 putative glutaredoxin protein 3503436 11811527 BCGMEX_3220 Mycobacterium bovis BCG str. Mexico putative glutaredoxin protein YP_005172674.1 3503182 D 717522 CDS YP_005172675.1 378772942 11811528 complement(3503449..3504390) 1 NC_016804.1 Differs from Rv3199c by 1aa, P237Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; NADH pyrophosphatase 3504390 nudC 11811528 nudC Mycobacterium bovis BCG str. Mexico NADH pyrophosphatase YP_005172675.1 3503449 R 717522 CDS YP_005172676.1 378772943 11811529 complement(3504449..3505516) 1 NC_016804.1 Differs from Rv3200c by 1aa, D12N in Mycobacterium bovis , Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane cation transporte 3505516 11811529 BCGMEX_3222c Mycobacterium bovis BCG str. Mexico putative transmembrane cation transporte YP_005172676.1 3504449 R 717522 CDS YP_005172677.1 378772944 11811530 complement(3505578..3508883) 1 NC_016804.1 ATP-dependent DNA helicase 3508883 11811530 BCGMEX_3223c Mycobacterium bovis BCG str. Mexico ATP-dependent DNA helicase YP_005172677.1 3505578 R 717522 CDS YP_005172678.1 378772945 11811531 complement(3508880..3512047) 1 NC_016804.1 Differs from Rv3202c by 1aa, A748V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ATP-dependent DNA helicase 3512047 11811531 BCGMEX_3224c Mycobacterium bovis BCG str. Mexico putative ATP-dependent DNA helicase YP_005172678.1 3508880 R 717522 CDS YP_005172679.1 378772946 11811532 3512124..3512342 1 NC_016804.1 hypothetical protein 3512342 11811532 BCGMEX_3225 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172679.1 3512124 D 717522 CDS YP_005172680.1 378772947 11811533 3512484..3513158 1 NC_016804.1 putative lipase 3513158 lipV 11811533 lipV Mycobacterium bovis BCG str. Mexico putative lipase YP_005172680.1 3512484 D 717522 CDS YP_005172681.1 378772948 11811534 3513161..3513466 1 NC_016804.1 Differs from Rv3204 by 1aa, A34T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative DNA-methyltransferase 3513466 11811534 BCGMEX_3227 Mycobacterium bovis BCG str. Mexico putative DNA-methyltransferase YP_005172681.1 3513161 D 717522 CDS YP_005172682.1 378772949 11811535 complement(3513473..3514351) 1 NC_016804.1 hypothetical protein 3514351 11811535 BCGMEX_3228c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172682.1 3513473 R 717522 CDS YP_005172683.1 378772950 11811536 complement(3514378..3515556) 1 NC_016804.1 Differs from Mb3231c by 1aa, addition of P197 in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; molybdenum cofactor biosynthesis protein 3515556 moeB1 11811536 moeB1 Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein YP_005172683.1 3514378 R 717522 CDS YP_005172684.1 378772951 11811537 complement(3515647..3516504) 1 NC_016804.1 Differs from Rv3207c by 1aa, N157D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3516504 11811537 BCGMEX_3230c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172684.1 3515647 R 717522 CDS YP_005172685.1 378772952 11811538 3516850..3517536 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3517536 11811538 BCGMEX_3231 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172685.1 3516850 D 717522 CDS YP_005172686.1 378772953 11811539 complement(3517523..3517795) 1 NC_016804.1 hypothetical protein 3517795 11811539 BCGMEX_3232c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172686.1 3517523 R 717522 CDS YP_005172687.1 378772954 11811540 complement(3518002..3518331) 1 NC_016804.1 putative helicase 3518331 11811540 BCGMEX_3233c Mycobacterium bovis BCG str. Mexico putative helicase YP_005172687.1 3518002 R 717522 CDS YP_005172688.1 378772955 11811541 3518120..3518680 1 NC_016804.1 putative threonine and proline rich protein 3518680 11811541 BCGMEX_3234 Mycobacterium bovis BCG str. Mexico putative threonine and proline rich protein YP_005172688.1 3518120 D 717522 CDS YP_005172689.1 378772956 11811542 complement(3518690..3519385) 1 NC_016804.1 hypothetical protein 3519385 11811542 BCGMEX_3235c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172689.1 3518690 R 717522 CDS YP_005172690.1 378772957 11811543 3519644..3521227 1 NC_016804.1 Differs from Mb3237 by 1aa, V17A in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative ATP-dependent RNA helicase 3521227 rhlE 11811543 rhlE Mycobacterium bovis BCG str. Mexico putative ATP-dependent RNA helicase YP_005172690.1 3519644 D 717522 CDS YP_005172691.1 378772958 11811544 3521240..3522463 1 NC_016804.1 Differs from Mb3238 by 1aa, G225D, and from Rv3212 by 2aa, G225D, A250V in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3522463 11811544 BCGMEX_3237 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172691.1 3521240 D 717522 CDS YP_005172692.1 378772959 11811545 complement(3522539..3523339) 1 NC_016804.1 Differs from Rv3213c by 1aa, E144K in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative soj/parA-related protein 3523339 11811545 BCGMEX_3238c Mycobacterium bovis BCG str. Mexico putative soj/parA-related protein YP_005172692.1 3522539 R 717522 CDS YP_005172693.1 378772960 11811546 3523493..3524104 1 NC_016804.1 putative phosphoglycerate mutase 3524104 gpm2_1 11811546 gpm2_1 Mycobacterium bovis BCG str. Mexico putative phosphoglycerate mutase YP_005172693.1 3523493 D 717522 CDS YP_005172694.1 378772961 11811547 3524101..3525219 1 NC_016804.1 putative isochorismate synthase 3525219 entC_1 11811547 entC_1 Mycobacterium bovis BCG str. Mexico putative isochorismate synthase YP_005172694.1 3524101 D 717522 CDS YP_005172695.1 378772962 11811548 3525367..3525699 1 NC_016804.1 putative acetyltransferase 3525699 11811548 BCGMEX_3241 Mycobacterium bovis BCG str. Mexico putative acetyltransferase YP_005172695.1 3525367 D 717522 CDS YP_005172696.1 378772963 11811549 complement(3525651..3526082) 1 NC_016804.1 putative integral membrane protein 3526082 11811549 BCGMEX_3242c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172696.1 3525651 R 717522 CDS YP_005172697.1 378772964 11811550 3526315..3527280 1 NC_016804.1 hypothetical protein 3527280 11811550 BCGMEX_3243 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172697.1 3526315 D 717522 CDS YP_005172698.1 378772965 11811551 3527560..3527814 1 NC_016804.1 putative transcriptional regulatory protein whiB-like protein 3527814 whiB1_1 11811551 whiB1_1 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein whiB-like protein YP_005172698.1 3527560 D 717522 CDS YP_005172699.1 378772966 11811552 complement(3527876..3529381) 1 NC_016804.1 Differs from Rv3220c by 1aa, N47D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative sensor histidine kinase pdtaS 3529381 11811552 BCGMEX_3245c Mycobacterium bovis BCG str. Mexico putative sensor histidine kinase pdtaS YP_005172699.1 3527876 R 717522 CDS YP_005172700.1 378772967 11811553 complement(3529398..3529613) 1 NC_016804.1 hypothetical protein 3529613 11811553 BCGMEX_3246c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172700.1 3529398 R 717522 CDS YP_005172701.1 378772968 11811554 complement(3529898..3530203) 1 NC_016804.1 putative anti-sigma factor 3530203 11811554 BCGMEX_3247c Mycobacterium bovis BCG str. Mexico putative anti-sigma factor YP_005172701.1 3529898 R 717522 CDS YP_005172702.1 378772969 11811555 complement(3530200..3530751) 1 NC_016804.1 hypothetical protein 3530751 11811555 BCGMEX_3248c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172702.1 3530200 R 717522 CDS YP_005172703.1 378772970 11811556 complement(3530748..3531398) 1 NC_016804.1 RNA polymerase sigma-E factor 3531398 rpoE_1 11811556 rpoE_1 Mycobacterium bovis BCG str. Mexico RNA polymerase sigma-E factor YP_005172703.1 3530748 R 717522 CDS YP_005172704.1 378772971 11811557 3531698..3532546 1 NC_016804.1 Short-chain dehydrogenase/reductase family 3532546 11811557 BCGMEX_3250 Mycobacterium bovis BCG str. Mexico Short-chain dehydrogenase/reductase family YP_005172704.1 3531698 D 717522 CDS YP_005172705.1 378772972 11811558 3532482..3532670 1 NC_016804.1 hypothetical protein 3532670 11811558 BCGMEX_3251 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172705.1 3532482 D 717522 CDS YP_005172706.1 378772973 11811559 3532648..3532866 1 NC_016804.1 hypothetical protein 3532866 11811559 BCGMEX_3252c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172706.1 3532648 D 717522 CDS YP_005172707.1 378772974 11811560 complement(3532863..3534287) 1 NC_016804.1 Differs from Rv3225c by 1aa T306A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transferase 3534287 11811560 BCGMEX_3253c Mycobacterium bovis BCG str. Mexico putative transferase YP_005172707.1 3532863 R 717522 CDS YP_005172708.1 378772975 11811561 complement(3534411..3535169) 1 NC_016804.1 hypothetical protein 3535169 11811561 BCGMEX_3254c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172708.1 3534411 R 717522 CDS YP_005172709.1 378772976 11811562 3535224..3536576 1 NC_016804.1 Differs from Mb3256 by 1aa, R150H in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; 3-phosphoshikimate 1-carboxyvinyltransferase 3536576 aroA_1 11811562 aroA_1 Mycobacterium bovis BCG str. Mexico 3-phosphoshikimate 1-carboxyvinyltransferase YP_005172709.1 3535224 D 717522 CDS YP_005172710.1 378772977 11811563 3536573..3537565 1 NC_016804.1 Differs from Rv3228, Mb3257 and BCG_3351 by 1aa, D169G in Mycobacterium bovis BCG Pasteur and BCG Mexico; hypothetical protein 3537565 11811563 BCGMEX_3256 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172710.1 3536573 D 717522 CDS YP_005172711.1 378772978 11811564 complement(3537598..3538881) 1 NC_016804.1 putative linoleoyl-CoA desaturase 3538881 desA3_1 11811564 desA3_1 Mycobacterium bovis BCG str. Mexico putative linoleoyl-CoA desaturase YP_005172711.1 3537598 R 717522 CDS YP_005172712.1 378772979 11811565 complement(3538959..3540101) 1 NC_016804.1 Differs from Rv3230c by 1aa, C105R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 3540101 11811565 BCGMEX_3258c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172712.1 3538959 R 717522 CDS YP_005172713.1 378772980 11811566 complement(3540211..3540720) 1 NC_016804.1 In DU2 of BCG Pasteur and BCG Mexico, the second copy (BCG_3354c) is truncated; hypothetical protein 3540720 11811566 BCGMEX_3259c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172713.1 3540211 R 717522 CDS YP_005172714.1 378772981 11811567 complement(3540717..3541604) 1 NC_016804.1 putative transcriptional regulatory protein 3541604 pvdS 11811567 pvdS Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005172714.1 3540717 R 717522 CDS YP_005172715.1 378772982 11811568 complement(3541628..3543037) 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, Rv3234c and Rv3233c exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Mexico and Mycobacterium bovis, a single base insertion leads to a single product that is more similar to Rv3234c; hypothetical protein 3543037 11811568 BCGMEX_3261c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172715.1 3541628 R 717522 CDS YP_005172716.1 378772983 11811569 3543148..3543789 1 NC_016804.1 hypothetical protein 3543789 11811569 BCGMEX_3262 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172716.1 3543148 D 717522 CDS YP_005172717.1 378772984 11811570 complement(3543807..3544964) 1 NC_016804.1 putative integral membrane transport protein 3544964 11811570 BCGMEX_3263c Mycobacterium bovis BCG str. Mexico putative integral membrane transport protein YP_005172717.1 3543807 R 717522 CDS YP_005172718.1 378772985 11811571 complement(3544969..3545451) 1 NC_016804.1 hypothetical protein 3545451 11811571 BCGMEX_3264c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172718.1 3544969 R 717522 CDS YP_005172719.1 378772986 11811572 complement(3545512..3546246) 1 NC_016804.1 putative integral membrane protein 3546246 11811572 BCGMEX_3265c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172719.1 3545512 R 717522 CDS YP_005172720.1 378772987 11811573 complement(3546305..3549451) 1 NC_016804.1 Differs from Mb3267c by 1aa, R867H in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane transport protein 3549451 11811573 BCGMEX_3266c Mycobacterium bovis BCG str. Mexico putative transmembrane transport protein YP_005172720.1 3546305 R 717522 CDS YP_005172721.1 378772988 11811574 complement(3549530..3552379) 1 NC_016804.1 protein translocase subunit 3552379 secA1 11811574 secA1 Mycobacterium bovis BCG str. Mexico protein translocase subunit YP_005172721.1 3549530 R 717522 CDS YP_005172722.1 378772989 11811575 complement(3552458..3553102) 1 NC_016804.1 hypothetical protein 3553102 11811575 BCGMEX_3268c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172722.1 3552458 R 717522 CDS YP_005172723.1 378772990 11811576 complement(3553418..3554059) 1 NC_016804.1 Differs from Rv3242c and Mb3270c by 1aa, S89L in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3554059 11811576 BCGMEX_3269c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172723.1 3553418 R 717522 CDS YP_005172724.1 378772991 11811577 complement(3554097..3554939) 1 NC_016804.1 hypothetical protein 3554939 11811577 BCGMEX_3270c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172724.1 3554097 R 717522 CDS YP_005172725.1 378772992 11811578 complement(3555007..3556758) 1 NC_016804.1 Differs from Rv3244c by 2aa, G142D, L394S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 3556758 lpqB 11811578 lpqB Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172725.1 3555007 R 717522 CDS YP_005172726.1 378772993 11811579 complement(3556758..3558461) 1 NC_016804.1 Differs from Rv3245c by 1aa, L517M in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Sensor histidine kinase 3558461 mtrB 11811579 mtrB Mycobacterium bovis BCG str. Mexico Sensor histidine kinase YP_005172726.1 3556758 R 717522 CDS YP_005172727.1 378772994 11811580 complement(3558511..3559197) 1 NC_016804.1 DNA-binding response regulator 3559197 mtrA 11811580 mtrA Mycobacterium bovis BCG str. Mexico DNA-binding response regulator YP_005172727.1 3558511 R 717522 CDS YP_005172728.1 378772995 11811581 complement(3559267..3559911) 1 NC_016804.1 thymidylate kinase 3559911 tmk 11811581 tmk Mycobacterium bovis BCG str. Mexico thymidylate kinase YP_005172728.1 3559267 R 717522 CDS YP_005172729.1 378772996 11811582 complement(3560008..3561495) 1 NC_016804.1 Differs from Mb3276c by 1aa V189I in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; adenosylhomocysteinase 3561495 sahH 11811582 sahH Mycobacterium bovis BCG str. Mexico adenosylhomocysteinase YP_005172729.1 3560008 R 717522 CDS YP_005172730.1 378772997 11811583 complement(3561600..3562235) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3562235 11811583 BCGMEX_3276c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172730.1 3561600 R 717522 CDS YP_005172731.1 378772998 11811584 complement(3562232..3562414) 1 NC_016804.1 Rubredoxin 3562414 11811584 BCGMEX_3277c Mycobacterium bovis BCG str. Mexico Rubredoxin YP_005172731.1 3562232 R 717522 CDS YP_005172732.1 378772999 11811585 complement(3562419..3562586) 1 NC_016804.1 Rubredoxin 3562586 11811585 BCGMEX_3278c Mycobacterium bovis BCG str. Mexico Rubredoxin YP_005172732.1 3562419 R 717522 CDS YP_005172733.1 378773000 11811586 complement(3562586..3563836) 1 NC_016804.1 alkane-1 monooxygenase 3563836 alkB 11811586 alkB Mycobacterium bovis BCG str. Mexico alkane-1 monooxygenase YP_005172733.1 3562586 R 717522 CDS YP_005172734.1 378773001 11811587 complement(3563945..3565432) 1 NC_016804.1 putative cationic amino acid transport integral membrane protein 3565432 11811587 BCGMEX_3280c Mycobacterium bovis BCG str. Mexico putative cationic amino acid transport integral membrane protein YP_005172734.1 3563945 R 717522 CDS YP_005172735.1 378773002 11811588 3565523..3566911 1 NC_016804.1 hypothetical protein 3566911 11811588 BCGMEX_3281 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172735.1 3565523 D 717522 CDS YP_005172736.1 378773003 11811589 complement(3566889..3568115) 1 NC_016804.1 Mannose-6-phosphate isomerase 3568115 manA 11811589 manA Mycobacterium bovis BCG str. Mexico Mannose-6-phosphate isomerase YP_005172736.1 3566889 R 717522 CDS YP_005172737.1 378773004 11811590 complement(3568123..3569163) 1 NC_016804.1 hypothetical protein 3569163 11811590 BCGMEX_3283c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172737.1 3568123 R 717522 CDS YP_005172738.1 378773005 11811591 complement(3569160..3570557) 1 NC_016804.1 Differs from Rv3257c by 1aa, L206S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phosphomannomutase 3570557 manB 11811591 manB Mycobacterium bovis BCG str. Mexico phosphomannomutase YP_005172738.1 3569160 R 717522 CDS YP_005172739.1 378773006 11811592 complement(3570659..3571150) 1 NC_016804.1 hypothetical protein 3571150 11811592 BCGMEX_3285c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172739.1 3570659 R 717522 CDS YP_005172740.1 378773007 11811593 3571273..3571692 1 NC_016804.1 hypothetical protein 3571692 11811593 BCGMEX_3286 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172740.1 3571273 D 717522 CDS YP_005172741.1 378773008 11811594 complement(3571720..3571989) 1 NC_016804.1 transcriptional regulatory protein WhiB-like protein 3571989 whiB2 11811594 whiB2 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein WhiB-like protein YP_005172741.1 3571720 R 717522 CDS YP_005172742.1 378773009 11811595 3572391..3573386 1 NC_016804.1 LPPG:FO 2-phospho-L-lactate transferase 3573386 cofD 11811595 cofD Mycobacterium bovis BCG str. Mexico LPPG:FO 2-phospho-L-lactate transferase YP_005172742.1 3572391 D 717522 CDS YP_005172743.1 378773010 11811596 3573383..3574729 1 NC_016804.1 F420-0:gamma-glutamyl ligase 3574729 cofE 11811596 cofE Mycobacterium bovis BCG str. Mexico F420-0:gamma-glutamyl ligase YP_005172743.1 3573383 D 717522 CDS YP_005172744.1 378773011 11811597 3575025..3576686 1 NC_016804.1 putative DNA methylase 3576686 11811597 BCGMEX_3290 Mycobacterium bovis BCG str. Mexico putative DNA methylase YP_005172744.1 3575025 D 717522 CDS YP_005172745.1 378773012 11811598 complement(3576746..3577825) 1 NC_016804.1 putative mannose-1-phosphate guanyltransferase 3577825 manC 11811598 manC Mycobacterium bovis BCG str. Mexico putative mannose-1-phosphate guanyltransferase YP_005172745.1 3576746 R 717522 CDS YP_005172746.1 378773013 11811599 complement(3577827..3578720) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, an in-frame deletion of 12 bp leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (297 aa versus 301aa); dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase 3578720 wbbL1 11811599 wbbL1 Mycobacterium bovis BCG str. Mexico dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase YP_005172746.1 3577827 R 717522 CDS YP_005172747.1 378773014 11811600 complement(3578731..3579645) 1 NC_016804.1 Differs from Rv3266c by 1aa, P257S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; dTDP-4-dehydrorhamnose reductase 3579645 rmld 11811600 rmld Mycobacterium bovis BCG str. Mexico dTDP-4-dehydrorhamnose reductase YP_005172747.1 3578731 R 717522 CDS YP_005172748.1 378773015 11811601 3579721..3581217 1 NC_016804.1 hypothetical protein 3581217 11811601 BCGMEX_3294 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172748.1 3579721 D 717522 CDS YP_005172749.1 378773016 11811602 3581256..3581945 1 NC_016804.1 hypothetical protein 3581945 11811602 BCGMEX_3295 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172749.1 3581256 D 717522 CDS YP_005172750.1 378773017 11811603 3582070..3582351 1 NC_016804.1 hypothetical protein 3582351 11811603 BCGMEX_3296 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172750.1 3582070 D 717522 CDS YP_005172751.1 378773018 11811604 3582362..3584518 1 NC_016804.1 putative metal cation-transporting P-type ATPase C 3584518 ctpC 11811604 ctpC Mycobacterium bovis BCG str. Mexico putative metal cation-transporting P-type ATPase C YP_005172751.1 3582362 D 717522 CDS YP_005172752.1 378773019 11811605 complement(3584515..3585183) 1 NC_016804.1 putative integral membrane protein 3585183 11811605 BCGMEX_3298c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172752.1 3584515 R 717522 CDS YP_005172753.1 378773020 11811606 3585284..3586468 1 NC_016804.1 Differs from Mb3300 by 1aa, R259G, and from Rv3272 by 2aa, R259G, S347N in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3586468 11811606 BCGMEX_3299 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172753.1 3585284 D 717522 CDS YP_005172754.1 378773021 11811607 3586473..3588767 1 NC_016804.1 carbonic anhydrase 3588767 11811607 BCGMEX_3300 Mycobacterium bovis BCG str. Mexico carbonic anhydrase YP_005172754.1 3586473 D 717522 CDS YP_005172755.1 378773022 11811608 complement(3588756..3589925) 1 NC_016804.1 putative acyl-CoA dehydrogenase 3589925 fadE25 11811608 fadE25 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005172755.1 3588756 R 717522 CDS YP_005172756.1 378773023 11811609 complement(3589950..3590474) 1 NC_016804.1 Differs from Rv3275c by 1aa, R125G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; phosphoribosylaminoimidazole carboxylase catalytic subunit 3590474 purE 11811609 purE Mycobacterium bovis BCG str. Mexico phosphoribosylaminoimidazole carboxylase catalytic subunit YP_005172756.1 3589950 R 717522 CDS YP_005172757.1 378773024 11811610 complement(3590471..3591760) 1 NC_016804.1 phosphoribosylaminoimidazole carboxylase ATPase subunit 3591760 purK 11811610 purK Mycobacterium bovis BCG str. Mexico phosphoribosylaminoimidazole carboxylase ATPase subunit YP_005172757.1 3590471 R 717522 CDS YP_005172758.1 378773025 11811611 3591714..3592532 1 NC_016804.1 Differs from Rv3277 by 1 aa, L272S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 3592532 11811611 BCGMEX_3304 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172758.1 3591714 D 717522 CDS YP_005172759.1 378773026 11811612 complement(3592487..3593005) 1 NC_016804.1 Differs from Rv3278c by 1aa, K160E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur and BCG Mexico. Differs from Rv3278c by 2aa, T54I, K160E in Mycobacterium bovis BCG Tokyo.; putative transmembrane protein 3593005 11811612 BCGMEX_3305c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172759.1 3592487 R 717522 CDS YP_005172760.1 378773027 11811613 complement(3593048..3593848) 1 NC_016804.1 Differs from Rv3279c by 1aa, N211D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; biotin--[acetyl-CoA-carboxylase] synthetase; putative biotin operon repressor 3593848 birA 11811613 birA Mycobacterium bovis BCG str. Mexico putative biotin operon repressor YP_005172760.1 3593048 R 717522 CDS YP_005172761.1 378773028 11811614 3593898..3595544 1 NC_016804.1 Differs from Rv3280 by 1aa, A448V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative propionyl-CoA carboxylase beta chain 5 3595544 accD5 11811614 accD5 Mycobacterium bovis BCG str. Mexico putative propionyl-CoA carboxylase beta chain 5 YP_005172761.1 3593898 D 717522 CDS YP_005172762.1 378773029 11811615 3595525..3595995 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, an in-frame deletion of 63 bp leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (156 aa versus 177aa). Loss of tandem repeat SRVSGTNEVSDGNETNNPAPV; hypothetical protein 3595995 11811615 BCGMEX_3308 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172762.1 3595525 D 717522 CDS YP_005172763.1 378773030 11811616 3595992..3596660 1 NC_016804.1 Differs from Rv3282 by 1aa, S133A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and Mexico; Maf-like protein 3596660 11811616 BCGMEX_3309 Mycobacterium bovis BCG str. Mexico Maf-like protein YP_005172763.1 3595992 D 717522 CDS YP_005172764.1 378773031 11811617 3596701..3597594 1 NC_016804.1 Differs from Mb3311 by 1aa, G170D in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative thiosulfate sulfurtransferase 3597594 sseA 11811617 sseA Mycobacterium bovis BCG str. Mexico putative thiosulfate sulfurtransferase YP_005172764.1 3596701 D 717522 CDS YP_005172765.1 378773032 11811618 3597591..3598022 1 NC_016804.1 hypothetical protein 3598022 11811618 BCGMEX_3311 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172765.1 3597591 D 717522 CDS YP_005172766.1 378773033 11811619 3598130..3599932 1 NC_016804.1 putative acetyl-/propionyl-coenzyme A carboxylase alpha chain 3599932 accA3 11811619 accA3 Mycobacterium bovis BCG str. Mexico putative acetyl-/propionyl-coenzyme A carboxylase alpha chain YP_005172766.1 3598130 D 717522 CDS YP_005172767.1 378773034 11811620 complement(3599942..3600727) 1 NC_016804.1 RNA polymerase sigma factor SigF 3600727 sigF 11811620 sigF Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor SigF YP_005172767.1 3599942 R 717522 CDS YP_005172768.1 378773035 11811621 complement(3600724..3601161) 1 NC_016804.1 anti-sigma factor 3601161 rsbW 11811621 rsbW Mycobacterium bovis BCG str. Mexico anti-sigma factor YP_005172768.1 3600724 R 717522 CDS YP_005172769.1 378773036 11811622 complement(3601359..3601772) 1 NC_016804.1 usfY; hypothetical protein 3601772 11811622 BCGMEX_3315c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172769.1 3601359 R 717522 CDS YP_005172770.1 378773037 11811623 complement(3601807..3602184) 1 NC_016804.1 putative transmembrane protein 3602184 11811623 BCGMEX_3316c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172770.1 3601807 R 717522 CDS YP_005172771.1 378773038 11811624 complement(3602218..3603567) 1 NC_016804.1 L-lysine aminotransferase 3603567 lat 11811624 lat Mycobacterium bovis BCG str. Mexico L-lysine aminotransferase YP_005172771.1 3602218 R 717522 CDS YP_005172772.1 378773039 11811625 complement(3603618..3604070) 1 NC_016804.1 Differs from Rv3291c by 1aa, V22A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transcriptional regulatory protein, AsnC-family 3604070 11811625 BCGMEX_3318c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, AsnC-family YP_005172772.1 3603618 R 717522 CDS YP_005172773.1 378773040 11811626 3604101..3605348 1 NC_016804.1 hypothetical protein 3605348 11811626 BCGMEX_3319 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172773.1 3604101 D 717522 CDS YP_005172774.1 378773041 11811627 3605375..3606859 1 NC_016804.1 Differs from Rv3293 by 1aa, C273G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative piperideine-6-carboxylic acid dehydrogenase 3606859 pcd 11811627 pcd Mycobacterium bovis BCG str. Mexico putative piperideine-6-carboxylic acid dehydrogenase YP_005172774.1 3605375 D 717522 CDS YP_005172775.1 378773042 11811628 complement(3606959..3607768) 1 NC_016804.1 hypothetical protein 3607768 11811628 BCGMEX_3321c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172775.1 3606959 R 717522 CDS YP_005172776.1 378773043 11811629 3607839..3608504 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3608504 11811629 BCGMEX_3322 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172776.1 3607839 D 717522 CDS YP_005172777.1 378773044 11811630 3608548..3613089 1 NC_016804.1 Differs from Rv3296 by 3aa, M719V, N818D, E1059K in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur and BCG Mexico. Differs from Rv3296 by 4aa, T719V, M796L, N818D, E1059K in Mycobacterium bovis BCG Tokyo.; putative ATP-dependent helicase 3613089 lhr 11811630 lhr Mycobacterium bovis BCG str. Mexico putative ATP-dependent helicase YP_005172777.1 3608548 D 717522 CDS YP_005172778.1 378773045 11811631 3613093..3613860 1 NC_016804.1 DNA glycosylase 3613860 nei_1 11811631 nei_1 Mycobacterium bovis BCG str. Mexico DNA glycosylase YP_005172778.1 3613093 D 717522 CDS YP_005172779.1 378773046 11811632 complement(3613883..3614797) 1 NC_016804.1 putative esterase lipoprotein 3614797 lpqC 11811632 lpqC Mycobacterium bovis BCG str. Mexico putative esterase lipoprotein YP_005172779.1 3613883 R 717522 CDS YP_005172780.1 378773047 11811633 complement(3614824..3617736) 1 NC_016804.1 Differs from Rv3299c by 1aa, S204G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; arylsulfatase 3617736 atsB_1 11811633 atsB_1 Mycobacterium bovis BCG str. Mexico arylsulfatase YP_005172780.1 3614824 R 717522 CDS YP_005172781.1 378773048 11811634 complement(3617756..3618673) 1 NC_016804.1 Differs from Mb3328c by 1aa, D52N in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Pseudouridine synthase 3618673 11811634 BCGMEX_3327c Mycobacterium bovis BCG str. Mexico Pseudouridine synthase YP_005172781.1 3617756 R 717522 CDS YP_005172782.1 378773049 11811635 complement(3618685..3619350) 1 NC_016804.1 Differs from Rv3301c and Mb3329c by 1aa, S74A in BCG Pasteur, BCG Tokyo and BCG Mexico; phosphate transport system regulatory protein PhoU 3619350 phoY1_1 11811635 phoY1_1 Mycobacterium bovis BCG str. Mexico phosphate transport system regulatory protein PhoU YP_005172782.1 3618685 R 717522 CDS YP_005172783.1 378773050 11811636 complement(3619458..3621215) 1 NC_016804.1 glycerol-3-phosphate dehydrogenase 3621215 glpD2_1 11811636 glpD2_1 Mycobacterium bovis BCG str. Mexico glycerol-3-phosphate dehydrogenase YP_005172783.1 3619458 R 717522 CDS YP_005172784.1 378773051 11811637 complement(3621296..3621895) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur and BCG Mexico, lpdA' is truncated and contains one endpoint of BCG-specific tandem duplication region, DU2. In Mycobacterium bovis, the CDS has 21 codons fewer than Rv3303c due to point mutation introducing stop codon; dihydrolipoamide dehydrogenase 3621895 lpdA 11811637 lpdA Mycobacterium bovis BCG str. Mexico dihydrolipoamide dehydrogenase YP_005172784.1 3621296 R 717522 CDS YP_005172785.1 378773052 11811638 complement(3621895..3622491) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur and BCG Mexico, Mb3333c is truncated compared to its homologs in Mycobacterium tuberculosis strain H37Rv (Rv3213c) and Mycobacterium bovis AF2122/97 (Mb3239c). It contains one endpoint of BCG-specific tandem duplication region, DU2. Differs from Rv3213c by 2aa, E144K and P198L in BCG Pasteur and BCG Mexico; putative soj/parA-related protein 3622491 11811638 BCGMEX_3331c Mycobacterium bovis BCG str. Mexico putative soj/parA-related protein YP_005172785.1 3621895 R 717522 CDS YP_005172786.1 378773053 11811639 3622645..3623256 1 NC_016804.1 putative phosphoglycerate mutase 3623256 gpm2_2 11811639 gpm2_2 Mycobacterium bovis BCG str. Mexico putative phosphoglycerate mutase YP_005172786.1 3622645 D 717522 CDS YP_005172787.1 378773054 11811640 3623253..3624371 1 NC_016804.1 putative isochorismate synthase 3624371 entC_2 11811640 entC_2 Mycobacterium bovis BCG str. Mexico putative isochorismate synthase YP_005172787.1 3623253 D 717522 CDS YP_005172788.1 378773055 11811641 3624519..3624851 1 NC_016804.1 putative acetyltransferase 3624851 11811641 BCGMEX_3334 Mycobacterium bovis BCG str. Mexico putative acetyltransferase YP_005172788.1 3624519 D 717522 CDS YP_005172789.1 378773056 11811642 complement(3624803..3625234) 1 NC_016804.1 putative integral membrane protein 3625234 11811642 BCGMEX_3335c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172789.1 3624803 R 717522 CDS YP_005172790.1 378773057 11811643 3625467..3626432 1 NC_016804.1 hypothetical protein 3626432 11811643 BCGMEX_3336 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172790.1 3625467 D 717522 CDS YP_005172791.1 378773058 11811644 3626712..3626966 1 NC_016804.1 transcriptional regulatory protein WhiB-like protein 3626966 whiB1_2 11811644 whiB1_2 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein WhiB-like protein YP_005172791.1 3626712 D 717522 CDS YP_005172792.1 378773059 11811645 complement(3627028..3628533) 1 NC_016804.1 Differs from Rv3220c by 1aa, N47D in Mycobacterium bovis BCG Pasteur and BCG Mexico; putative two component sensor kinase pdtaS 3628533 11811645 BCGMEX_3338c Mycobacterium bovis BCG str. Mexico putative two component sensor kinase pdtaS YP_005172792.1 3627028 R 717522 CDS YP_005172793.1 378773060 11811646 complement(3628550..3628765) 1 NC_016804.1 hypothetical protein 3628765 11811646 BCGMEX_3339c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172793.1 3628550 R 717522 CDS YP_005172794.1 378773061 11811647 complement(3629050..3629355) 1 NC_016804.1 putative anti-sigma factor 3629355 11811647 BCGMEX_3340c Mycobacterium bovis BCG str. Mexico putative anti-sigma factor YP_005172794.1 3629050 R 717522 CDS YP_005172795.1 378773062 11811648 complement(3629352..3629903) 1 NC_016804.1 hypothetical protein 3629903 11811648 BCGMEX_3341c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172795.1 3629352 R 717522 CDS YP_005172796.1 378773063 11811649 complement(3629900..3630550) 1 NC_016804.1 RNA polymerase sigma-E factor 3630550 rpoE_2 11811649 rpoE_2 Mycobacterium bovis BCG str. Mexico RNA polymerase sigma-E factor YP_005172796.1 3629900 R 717522 CDS YP_005172797.1 378773064 11811650 3630850..3631698 1 NC_016804.1 Short-chain dehydrogenase/reductase family 3631698 11811650 BCGMEX_3343 Mycobacterium bovis BCG str. Mexico Short-chain dehydrogenase/reductase family YP_005172797.1 3630850 D 717522 CDS YP_005172798.1 378773065 11811651 3631634..3631822 1 NC_016804.1 hypothetical protein 3631822 11811651 BCGMEX_3344 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172798.1 3631634 D 717522 CDS YP_005172799.1 378773066 11811652 3631800..3632018 1 NC_016804.1 hypothetical protein 3632018 11811652 BCGMEX_3345c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172799.1 3631800 D 717522 CDS YP_005172800.1 378773067 11811653 complement(3632015..3633439) 1 NC_016804.1 Differs from Rv3225c by 1aa T306A in Mycobacterium bovis BCG Pasteur and BCG Mexico; putative transferase 3633439 11811653 BCGMEX_3346c Mycobacterium bovis BCG str. Mexico putative transferase YP_005172800.1 3632015 R 717522 CDS YP_005172801.1 378773068 11811654 complement(3633563..3634321) 1 NC_016804.1 hypothetical protein 3634321 11811654 BCGMEX_3347c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172801.1 3633563 R 717522 CDS YP_005172802.1 378773069 11811655 3634376..3635728 1 NC_016804.1 Differs from Mb3256 by 1aa, R150H in BCG Pasteur and BCG Mexico; 3-phosphoshikimate 1-carboxyvinyltransferase 3635728 aroA_2 11811655 aroA_2 Mycobacterium bovis BCG str. Mexico 3-phosphoshikimate 1-carboxyvinyltransferase YP_005172802.1 3634376 D 717522 CDS YP_005172803.1 378773070 11811656 3635725..3636717 1 NC_016804.1 Differs from Rv3228, Mb3257 and BCG_3351 by 1aa, D169G in Mycobacterium bovis BCG Pasteur and BCG Mexico; hypothetical protein 3636717 11811656 BCGMEX_3349 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172803.1 3635725 D 717522 CDS YP_005172804.1 378773071 11811657 complement(3636750..3638033) 1 NC_016804.1 putative linoleoyl-CoA desaturase 3638033 desA3_2 11811657 desA3_2 Mycobacterium bovis BCG str. Mexico putative linoleoyl-CoA desaturase YP_005172804.1 3636750 R 717522 CDS YP_005172805.1 378773072 11811658 complement(3638111..3639253) 1 NC_016804.1 Differs from Rv3230c by 1aa, C105R in Mycobacterium bovis BCG Pasteur and BCG Mexico; putative oxidoreductase 3639253 11811658 BCGMEX_3351c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172805.1 3638111 R 717522 CDS YP_005172806.1 378773073 11811659 complement(3639308..3639730) 1 NC_016804.1 Internal deletion of DU2 leads to a truncated copy of Rv3231c and of Rv3290c in Mycobacterium bovis BCG Pasteur and BCG Mexico; L-lysine aminotransferase 3639730 lat' 11811659 lat' Mycobacterium bovis BCG str. Mexico L-lysine aminotransferase YP_005172806.1 3639308 R 717522 CDS YP_005172807.1 378773074 11811660 complement(3639781..3640233) 1 NC_016804.1 Differs from Rv3291c by 1aa, V22A in Mycobacterium bovis BCG Pasteur and BCG Mexico; putative transcriptional regulatory protein, AsnC-family 3640233 11811660 BCGMEX_3353c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, AsnC-family YP_005172807.1 3639781 R 717522 CDS YP_005172808.1 378773075 11811661 3640264..3641511 1 NC_016804.1 hypothetical protein 3641511 11811661 BCGMEX_3354 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172808.1 3640264 D 717522 CDS YP_005172809.1 378773076 11811662 3641538..3643022 1 NC_016804.1 Differs from Rv3293 by 1aa, C273G in Mycobacterium bovis BCG Pasteur and BCG Mexico; putative piperideine-6-carboxylic acid dehydrogenase 3643022 pcd_2 11811662 pcd_2 Mycobacterium bovis BCG str. Mexico putative piperideine-6-carboxylic acid dehydrogenase YP_005172809.1 3641538 D 717522 CDS YP_005172810.1 378773077 11811663 complement(3643122..3643931) 1 NC_016804.1 hypothetical protein 3643931 11811663 BCGMEX_3356c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172810.1 3643122 R 717522 CDS YP_005172811.1 378773078 11811664 3644002..3644667 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3644667 11811664 BCGMEX_3357 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172811.1 3644002 D 717522 CDS YP_005172812.1 378773079 11811665 3644711..3649252 1 NC_016804.1 Differs from Rv3296 by 3aa, M719V, N818D, E1059K in Mycobacterium bovis BCG Pasteur and BCG Mexico; putative ATP-dependent helicase 3649252 lhr_2 11811665 lhr_2 Mycobacterium bovis BCG str. Mexico putative ATP-dependent helicase YP_005172812.1 3644711 D 717522 CDS YP_005172813.1 378773080 11811666 3649256..3650023 1 NC_016804.1 DNA glycosylase 3650023 nei_2 11811666 nei_2 Mycobacterium bovis BCG str. Mexico DNA glycosylase YP_005172813.1 3649256 D 717522 CDS YP_005172814.1 378773081 11811667 complement(3650046..3650960) 1 NC_016804.1 putative esterase lipoprotein 3650960 lpqC_2 11811667 lpqC_2 Mycobacterium bovis BCG str. Mexico putative esterase lipoprotein YP_005172814.1 3650046 R 717522 CDS YP_005172815.1 378773082 11811668 complement(3650987..3653899) 1 NC_016804.1 Differs from Rv3299c by 1aa, S204G in Mycobacterium bovis BCG Pasteur and BCG Mexico; arylsulfatase 3653899 atsB_2 11811668 atsB_2 Mycobacterium bovis BCG str. Mexico arylsulfatase YP_005172815.1 3650987 R 717522 CDS YP_005172816.1 378773083 11811669 complement(3653919..3654836) 1 NC_016804.1 Differs from Mb3328c by 1aa, D52N in Mycobacterium bovis BCG Pasteur and BCG Mexico; Pseudouridine synthase 3654836 11811669 BCGMEX_3362c Mycobacterium bovis BCG str. Mexico Pseudouridine synthase YP_005172816.1 3653919 R 717522 CDS YP_005172817.1 378773084 11811670 complement(3654848..3655513) 1 NC_016804.1 Differs from Rv3301c and Mb3329c by 1aa, S74A in BCG Pasteur and BCG Mexico; phosphate transport system regulatory protein PhoU 3655513 phoY1_2 11811670 phoY1_2 Mycobacterium bovis BCG str. Mexico phosphate transport system regulatory protein PhoU YP_005172817.1 3654848 R 717522 CDS YP_005172818.1 378773085 11811671 complement(3655621..3657378) 1 NC_016804.1 glycerol-3-phosphate dehydrogenase 3657378 glpD2_2 11811671 glpD2_2 Mycobacterium bovis BCG str. Mexico glycerol-3-phosphate dehydrogenase YP_005172818.1 3655621 R 717522 CDS YP_005172819.1 378773086 11811672 complement(3657459..3658874) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur,BCG Mexico and Mycobacterium bovis, truncation due to a single base transversion results in a shorter product compared to its homolog in Mycobacterium tuberculosis stain H37Rv (471 aa versus 493 aa). Differs from Rv3303c by 2aa, A29T, S308L in Mycobacterium bovis BCG Pasteur and BCG Mexico; dihydrolipoamide dehydrogenase 3658874 lpdA 11811672 lpdA Mycobacterium bovis BCG str. Mexico dihydrolipoamide dehydrogenase YP_005172819.1 3657459 R 717522 CDS YP_005172820.1 378773087 11811673 3659077..3659556 1 NC_016804.1 hypothetical protein 3659556 11811673 BCGMEX_3366 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172820.1 3659077 D 717522 CDS YP_005172821.1 378773088 11811674 complement(3659575..3660744) 1 NC_016804.1 putative N-acyl-L-amino acid amidohydrolase 3660744 amiA1 11811674 amiA1 Mycobacterium bovis BCG str. Mexico putative N-acyl-L-amino acid amidohydrolase YP_005172821.1 3659575 R 717522 CDS YP_005172822.1 378773089 11811675 complement(3660741..3661925) 1 NC_016804.1 putative amidase 3661925 amiB1 11811675 amiB1 Mycobacterium bovis BCG str. Mexico putative amidase YP_005172822.1 3660741 R 717522 CDS YP_005172823.1 378773090 11811676 3661990..3662796 1 NC_016804.1 putative purine nucleoside phosphorylase 3662796 deoD 11811676 deoD Mycobacterium bovis BCG str. Mexico putative purine nucleoside phosphorylase YP_005172823.1 3661990 D 717522 CDS YP_005172824.1 378773091 11811677 3662800..3664404 1 NC_016804.1 Differs from Rv3308 by 1aa, G440S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative phosphomannomutase 3664404 pmmB 11811677 pmmB Mycobacterium bovis BCG str. Mexico putative phosphomannomutase YP_005172824.1 3662800 D 717522 CDS YP_005172825.1 378773092 11811678 complement(3664406..3665029) 1 NC_016804.1 uracil phosphoribosyltransferase 3665029 upp 11811678 upp Mycobacterium bovis BCG str. Mexico uracil phosphoribosyltransferase YP_005172825.1 3664406 R 717522 CDS YP_005172826.1 378773093 11811679 3665134..3666033 1 NC_016804.1 Differs from Rv3310 by 1aa, A171T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acid phosphatase 3666033 sapM 11811679 sapM Mycobacterium bovis BCG str. Mexico putative acid phosphatase YP_005172826.1 3665134 D 717522 CDS YP_005172827.1 378773094 11811680 3666057..3667319 1 NC_016804.1 hypothetical protein 3667319 11811680 BCGMEX_3373 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172827.1 3666057 D 717522 CDS YP_005172828.1 378773095 11811681 complement(3667340..3668266) 1 NC_016804.1 hypothetical protein 3668266 11811681 BCGMEX_3374c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172828.1 3667340 R 717522 CDS YP_005172829.1 378773096 11811682 complement(3668292..3668462) 1 NC_016804.1 hypothetical protein 3668462 11811682 BCGMEX_3375c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172829.1 3668292 R 717522 CDS YP_005172830.1 378773097 11811683 complement(3668641..3668952) 1 NC_016804.1 Secreted protein antigen 3668952 11811683 BCGMEX_3376c Mycobacterium bovis BCG str. Mexico Secreted protein antigen YP_005172830.1 3668641 R 717522 CDS YP_005172831.1 378773098 11811684 complement(3669023..3670120) 1 NC_016804.1 Adenosine deaminase 3670120 add 11811684 add Mycobacterium bovis BCG str. Mexico Adenosine deaminase YP_005172831.1 3669023 R 717522 CDS YP_005172832.1 378773099 11811685 complement(3670120..3671403) 1 NC_016804.1 Differs from Rv3314c by 1aa, W309R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; thymidine phosphorylase 3671403 deoA 11811685 deoA Mycobacterium bovis BCG str. Mexico thymidine phosphorylase YP_005172832.1 3670120 R 717522 CDS YP_005172833.1 378773100 11811686 complement(3671400..3671801) 1 NC_016804.1 cytidine deaminase 3671801 cdd 11811686 cdd Mycobacterium bovis BCG str. Mexico cytidine deaminase YP_005172833.1 3671400 R 717522 CDS YP_005172834.1 378773101 11811687 3672038..3672376 1 NC_016804.1 putative succinate dehydrogenase, cytochrome b-556 subunit 3672376 sdhC 11811687 sdhC Mycobacterium bovis BCG str. Mexico putative succinate dehydrogenase, cytochrome b-556 subunit YP_005172834.1 3672038 D 717522 CDS YP_005172835.1 378773102 11811688 3672373..3672807 1 NC_016804.1 Differs from Rv3317 by 1aa, L54V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Succinate dehydrogenase 3672807 sdhD 11811688 sdhD Mycobacterium bovis BCG str. Mexico Succinate dehydrogenase YP_005172835.1 3672373 D 717522 CDS YP_005172836.1 378773103 11811689 3672936..3674708 1 NC_016804.1 Succinate dehydrogenase flavoprotein subunit 3674708 sdhA 11811689 sdhA Mycobacterium bovis BCG str. Mexico Succinate dehydrogenase flavoprotein subunit YP_005172836.1 3672936 D 717522 CDS YP_005172837.1 378773104 11811690 3674708..3675499 1 NC_016804.1 Differs from Rv3319 by 1aa, E35D in BCG Pasteur and BCG Mexico, and by 2aa, E35D and T88A in BCG Tokyo; Succinate dehydrogenase iron-sulfur protein 3675499 sdhB 11811690 sdhB Mycobacterium bovis BCG str. Mexico Succinate dehydrogenase iron-sulfur protein YP_005172837.1 3674708 D 717522 CDS YP_005172838.1 378773105 11811691 complement(3675578..3676006) 1 NC_016804.1 hypothetical protein 3676006 11811691 BCGMEX_3384c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172838.1 3675578 R 717522 CDS YP_005172839.1 378773106 11811692 complement(3676010..3676252) 1 NC_016804.1 hypothetical protein 3676252 11811692 BCGMEX_3385c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172839.1 3676010 R 717522 CDS YP_005172840.1 378773107 11811693 complement(3676374..3676988) 1 NC_016804.1 putative methyltransferase 3676988 11811693 BCGMEX_3386c Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005172840.1 3676374 R 717522 CDS YP_005172841.1 378773108 11811694 complement(3676985..3677650) 1 NC_016804.1 putative MoaD-MoaE fusion protein 3677650 moaX 11811694 moaX Mycobacterium bovis BCG str. Mexico putative MoaD-MoaE fusion protein YP_005172841.1 3676985 R 717522 CDS YP_005172842.1 378773109 11811695 complement(3677651..3678184) 1 NC_016804.1 molybdenum cofactor biosynthesis protein C 3678184 moaC3 11811695 moaC3 Mycobacterium bovis BCG str. Mexico molybdenum cofactor biosynthesis protein C YP_005172842.1 3677651 R 717522 CDS YP_005172843.1 378773110 11811696 complement(3678181..3678555) 1 NC_016804.1 Belongs to the RvD5 region. Absent in Mycobacterium tuberculosis strain H37Rv; putative pterin-4-alpha-carbinolamine dehydratase 3678555 moaB3 11811696 moaB3 Mycobacterium bovis BCG str. Mexico putative pterin-4-alpha-carbinolamine dehydratase YP_005172843.1 3678181 R 717522 CDS YP_005172844.1 378773111 11811697 complement(3678652..3679716) 1 NC_016804.1 Belongs to the RvD5 region. Absent in Mycobacterium tuberculosis strain H37Rv; putative molybdenum cofactor biosynthesis protein A 3679716 moaA3 11811697 moaA3 Mycobacterium bovis BCG str. Mexico putative molybdenum cofactor biosynthesis protein A YP_005172844.1 3678652 R 717522 CDS YP_005172845.1 378773112 11811698 3679771..3680121 1 NC_016804.1 Belongs to the RvD5 region. Absent in Mycobacterium tuberculosis strain H37Rv but present in CDC1551 (CDS not annotated); hypothetical protein 3680121 11811698 BCGMEX_3391 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172845.1 3679771 D 717522 CDS YP_005172846.1 378773113 11811699 3680099..3680485 1 NC_016804.1 Belongs to the RvD5 region. Absent in Mycobacterium tuberculosis strain H37Rv but present in CDC1551 (CDS not annotated); hypothetical protein 3680485 11811699 BCGMEX_3392 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172846.1 3680099 D 717522 CDS YP_005172847.1 378773114 11811700 3680361..3681506 1 NC_016804.1 Belongs to the RvD5 region. Absent in Mycobacterium tuberculosis strain H37Rv; putative transcriptional regulator 3681506 embR2 11811700 embR2 Mycobacterium bovis BCG str. Mexico putative transcriptional regulator YP_005172847.1 3680361 D 717522 CDS YP_005172848.1 378773115 11811701 complement(3681601..3682245) 1 NC_016804.1 Belongs to the RvD5 region. Absent from Mycobacterium tuberculosis strain H37Rv; hypothetical protein 3682245 11811701 BCGMEX_3394c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172848.1 3681601 R 717522 CDS YP_005172849.1 378773116 11811702 3682412..3684124 1 NC_016804.1 putative transposase fusion protein 3684124 11811702 BCGMEX_3395 Mycobacterium bovis BCG str. Mexico putative transposase fusion protein YP_005172849.1 3682412 D 717522 CDS YP_005172850.1 378773117 11811703 complement(3684057..3684995) 1 NC_016804.1 Differs from Rv3328c by 1aa, Q41P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; RNA polymerase sigma factor 3684995 sigJ 11811703 sigJ Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005172850.1 3684057 R 717522 CDS YP_005172851.1 378773118 11811704 3685055..3686371 1 NC_016804.1 Differs from Rv3329 by 1aa, H122Q in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative aminotransferase 3686371 11811704 BCGMEX_3397 Mycobacterium bovis BCG str. Mexico putative aminotransferase YP_005172851.1 3685055 D 717522 CDS YP_005172852.1 378773119 11811705 3686440..3687657 1 NC_016804.1 putative penicillin-binding protein 3687657 dacB1 11811705 dacB1 Mycobacterium bovis BCG str. Mexico putative penicillin-binding protein YP_005172852.1 3686440 D 717522 CDS YP_005172853.1 378773120 11811706 3687753..3689246 1 NC_016804.1 Differs from Mycobacterium bovis (Mb3364) and Mycobacterium bovis BCG Tokyo by 5aa in-frame deletion at position 465, and from Rv3331 by same deletion and 1aa, L423P in Mycobacterium bovis BCG Pasteur and BCG Mexico; putative sugar-transport integral membrane protein 3689246 sugI 11811706 sugI Mycobacterium bovis BCG str. Mexico putative sugar-transport integral membrane protein YP_005172853.1 3687753 D 717522 CDS YP_005172854.1 378773121 11811707 3689243..3690394 1 NC_016804.1 N-acetylglucosamine-6-phosphate deacetylase 3690394 nagA 11811707 nagA Mycobacterium bovis BCG str. Mexico N-acetylglucosamine-6-phosphate deacetylase YP_005172854.1 3689243 D 717522 CDS YP_005172855.1 378773122 11811708 complement(3690585..3691430) 1 NC_016804.1 hypothetical protein 3691430 11811708 BCGMEX_3401c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172855.1 3690585 R 717522 CDS YP_005172856.1 378773123 11811709 3691575..3691886 1 NC_016804.1 hypothetical protein 3691886 11811709 BCGMEX_3402 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172856.1 3691575 D 717522 CDS YP_005172857.1 378773124 11811710 3691905..3692345 1 NC_016804.1 putative transcriptional regulatory protein, MerR-family 3692345 11811710 BCGMEX_3403 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, MerR-family YP_005172857.1 3691905 D 717522 CDS YP_005172858.1 378773125 11811711 complement(3692379..3693248) 1 NC_016804.1 Differs from Rv3335c and Mb3368c by 1aa, V86A in BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 3693248 11811711 BCGMEX_3404c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172858.1 3692379 R 717522 CDS YP_005172859.1 378773126 11811712 complement(3693269..3694279) 1 NC_016804.1 tryptophanyl-tRNA synthetase 3694279 trpS 11811712 trpS Mycobacterium bovis BCG str. Mexico tryptophanyl-tRNA synthetase YP_005172859.1 3693269 R 717522 CDS YP_005172860.1 378773127 11811713 3694304..3695197 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv3337 and Rv3338 exist as 2 genes with an overlap region between them. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base insertion leads to a single product; hypothetical protein 3695197 11811713 BCGMEX_3406 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172860.1 3694304 D 717522 CDS YP_005172861.1 378773128 11811714 complement(3695264..3696493) 1 NC_016804.1 Differs from Rv3339c and Mb3371c by 1aa, V198A in Mycobacterium bovis BCG Pasteur and BCG Mexico; isocitrate dehydrogenase 3696493 icd1 11811714 icd1 Mycobacterium bovis BCG str. Mexico isocitrate dehydrogenase YP_005172861.1 3695264 R 717522 CDS YP_005172862.1 378773129 11811715 3696776..3698125 1 NC_016804.1 Differs from Rv3340 and Mb3372 by 1aa, G83A in BCG Pasteur, BCG Tokyo and BCG Mexico; O-acetylhomoserine sulfhydrylase 3698125 metC 11811715 metC Mycobacterium bovis BCG str. Mexico O-acetylhomoserine sulfhydrylase YP_005172862.1 3696776 D 717522 CDS YP_005172863.1 378773130 11811716 3698137..3699276 1 NC_016804.1 homoserine O-acetyltransferase 3699276 metX 11811716 metX Mycobacterium bovis BCG str. Mexico homoserine O-acetyltransferase YP_005172863.1 3698137 D 717522 CDS YP_005172864.1 378773131 11811717 3699273..3700004 1 NC_016804.1 putative methyltransferase 3700004 11811717 BCGMEX_3410 Mycobacterium bovis BCG str. Mexico putative methyltransferase YP_005172864.1 3699273 D 717522 CDS YP_005172865.1 378773132 11811718 complement(3700013..3704029) 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 3555 bp in-frame deletion (RD19) leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv. Differs from Mb3375c by 1aa, A513V and from Rv3343c by several transitions in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3704029 PPE54 11811718 PPE54 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172865.1 3700013 R 717522 CDS YP_005172866.1 378773133 11811719 complement(3704078..3709708) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PE_PGRS50 and PE_PGRS49 exists as a single gene. In Mycobacterium bovis, a single base deletion splits PE_PGRS50 into 2 parts, PE_PGRS50a and PE_PGRS50b and a single base deletion leads to PE_PGRS49 and PE_PGRS50b existing as a single product. In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, the first deletion is absent leading to an unique single gene comprising PE_PGRS50 and PE_PGRS49; hypothetical protein 3709708 PE_PGRS50 11811719 PE_PGRS50 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172866.1 3704078 R 717522 CDS YP_005172867.1 378773134 11811720 complement(3710132..3710389) 1 NC_016804.1 hypothetical protein 3710389 11811720 BCGMEX_3413c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172867.1 3710132 R 717522 CDS YP_005172868.1 378773135 11811722 complement(3713827..3720117) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE55 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a single base deletion splits PPE55 into 2 parts, PPE55a and PPE55b. Differs from Rv3347c by many aa substitutions and from Mb3380c by 1 aa, P1089S in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3720117 PPE55a 11811722 PPE55a Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172868.1 3713827 R 717522 CDS YP_005172869.1 378773136 11811723 3720697..3721188 1 NC_016804.1 putative transposase 3721188 11811723 BCGMEX_3416 Mycobacterium bovis BCG str. Mexico putative transposase YP_005172869.1 3720697 D 717522 CDS YP_005172870.1 378773137 11811724 complement(3721225..3721965) 1 NC_016804.1 transposase 3721965 11811724 BCGMEX_3417c Mycobacterium bovis BCG str. Mexico transposase YP_005172870.1 3721225 R 717522 CDS YP_005172871.1 378773138 11811727 complement(3732724..3734022) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, PPE56 exists as a single gene. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, 2 frameshifts due to single base transversion and a single base deletion splits PPE56 into 3 parts, PPE56a, PPE56b and PPE56d. Differs from Rv3350c and Mb3385c by 2aa deletion at position 291 in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 3734022 PPE56a 11811727 PPE56a Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172871.1 3732724 R 717522 CDS YP_005172872.1 378773139 11811728 complement(3734266..3735060) 1 NC_016804.1 putative oxidoreductase 3735060 11811728 BCGMEX_3421c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172872.1 3734266 R 717522 CDS YP_005172873.1 378773140 11811729 complement(3735142..3735513) 1 NC_016804.1 putative oxidoreductase 3735513 11811729 BCGMEX_3422c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172873.1 3735142 R 717522 CDS YP_005172874.1 378773141 11811730 complement(3735656..3735916) 1 NC_016804.1 hypothetical protein 3735916 11811730 BCGMEX_3423c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172874.1 3735656 R 717522 CDS YP_005172875.1 378773142 11811731 3736031..3736420 1 NC_016804.1 Differs from Rv3354 by 1aa, A112V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3736420 11811731 BCGMEX_3424 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172875.1 3736031 D 717522 CDS YP_005172876.1 378773143 11811732 complement(3736434..3736727) 1 NC_016804.1 hypothetical protein 3736727 11811732 BCGMEX_3425c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172876.1 3736434 R 717522 CDS YP_005172877.1 378773144 11811733 complement(3736724..3737569) 1 NC_016804.1 Differs from Rv3356c by 1aa, P21Q in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; bifunctional protein: methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase 3737569 folD 11811733 folD Mycobacterium bovis BCG str. Mexico bifunctional protein: methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase YP_005172877.1 3736724 R 717522 CDS YP_005172878.1 378773145 11811734 3737693..3737968 1 NC_016804.1 hypothetical protein 3737968 11811734 BCGMEX_3427 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172878.1 3737693 D 717522 CDS YP_005172879.1 378773146 11811735 3737965..3738222 1 NC_016804.1 hypothetical protein 3738222 11811735 BCGMEX_3428 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172879.1 3737965 D 717522 CDS YP_005172880.1 378773147 11811736 3738264..3739454 1 NC_016804.1 putative oxidoreductase 3739454 11811736 BCGMEX_3429 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172880.1 3738264 D 717522 CDS YP_005172881.1 378773148 11811737 3739571..3739939 1 NC_016804.1 hypothetical protein 3739939 11811737 BCGMEX_3430 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172881.1 3739571 D 717522 CDS YP_005172882.1 378773149 11811738 complement(3739936..3740487) 1 NC_016804.1 hypothetical protein 3740487 11811738 BCGMEX_3431c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172882.1 3739936 R 717522 CDS YP_005172883.1 378773150 11811739 complement(3740494..3741075) 1 NC_016804.1 putative ATP/GTP-binding protein 3741075 11811739 BCGMEX_3432c Mycobacterium bovis BCG str. Mexico putative ATP/GTP-binding protein YP_005172883.1 3740494 R 717522 CDS YP_005172884.1 378773151 11811740 complement(3741056..3741424) 1 NC_016804.1 hypothetical protein 3741424 11811740 BCGMEX_3433c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172884.1 3741056 R 717522 CDS YP_005172885.1 378773152 11811741 complement(3741402..3741794) 1 NC_016804.1 Differs from Rv3364c and Mb3399c, by 1aa, L22P in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3741794 11811741 BCGMEX_3434c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172885.1 3741402 R 717522 CDS YP_005172886.1 378773153 11811742 complement(3741791..3744421) 1 NC_016804.1 hypothetical protein 3744421 11811742 BCGMEX_3435c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172886.1 3741791 R 717522 CDS YP_005172887.1 378773154 11811743 3744657..3745121 1 NC_016804.1 putative tRNA/rRNA methylase 3745121 spoU 11811743 spoU Mycobacterium bovis BCG str. Mexico putative tRNA/rRNA methylase YP_005172887.1 3744657 D 717522 CDS YP_005172888.1 378773155 11811744 3745488..3747263 1 NC_016804.1 In Mycobacterium bovis, insertions of 105 bp and of 9 bp lead to longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (626 aa versus 588 aa). In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, there is no 105 bp insertion but the 9 bp insertion is presentat codon 404. Differs also from Rv3367 by 1aa, S412G in BCG Pasteur, BCG Tokyo and BCG Mexico; PE PGRS family protein 3747263 PE_PGRS51 11811744 PE_PGRS51 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005172888.1 3745488 D 717522 CDS YP_005172889.1 378773156 11811745 complement(3747264..3747908) 1 NC_016804.1 putative oxidoreductase 3747908 11811745 BCGMEX_3438c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005172889.1 3747264 R 717522 CDS YP_005172890.1 378773157 11811746 3747907..3748341 1 NC_016804.1 hypothetical protein 3748341 11811746 BCGMEX_3439 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172890.1 3747907 D 717522 CDS YP_005172891.1 378773158 11811747 complement(3748430..3751669) 1 NC_016804.1 Differs from Rv3370c and Mb3405c by 1aa, S527N in BCG Pasteur, BCG Tokyo and BCG Mexico; error-prone DNA polymerase 3751669 dnaE2 11811747 dnaE2 Mycobacterium bovis BCG str. Mexico error-prone DNA polymerase YP_005172891.1 3748430 R 717522 CDS YP_005172892.1 378773159 11811748 3751861..3753201 1 NC_016804.1 Differs from Rv3371 by 2aa, G339R, V368I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative diacylglycerol O-acyltransferase 3753201 11811748 BCGMEX_3441 Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005172892.1 3751861 D 717522 CDS YP_005172893.1 378773160 11811749 3753243..3754418 1 NC_016804.1 putative trehalose-6-phosphate phosphatase 3754418 otsB2 11811749 otsB2 Mycobacterium bovis BCG str. Mexico putative trehalose-6-phosphate phosphatase YP_005172893.1 3753243 D 717522 CDS YP_005172894.1 378773161 11811750 3754655..3755545 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, echA18 and echA18' exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transversion leads to a single product; putative enoyl-CoA hydratase 3755545 echA18 11811750 echA18 Mycobacterium bovis BCG str. Mexico putative enoyl-CoA hydratase YP_005172894.1 3754655 D 717522 CDS YP_005172895.1 378773162 11811751 3755550..3756977 1 NC_016804.1 putative amidase 3756977 amiD 11811751 amiD Mycobacterium bovis BCG str. Mexico putative amidase YP_005172895.1 3755550 D 717522 CDS YP_005172896.1 378773163 11811752 3757085..3757738 1 NC_016804.1 hypothetical protein 3757738 11811752 BCGMEX_3445 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172896.1 3757085 D 717522 CDS YP_005172897.1 378773164 11811753 complement(3757830..3759281) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a frameshift due to a 4 bp to 3 bp substitution leads to a shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv; putative cyclase 3759281 11811753 BCGMEX_3446c Mycobacterium bovis BCG str. Mexico putative cyclase YP_005172897.1 3757830 R 717522 CDS YP_005172898.1 378773165 11811754 complement(3759286..3760176) 1 NC_016804.1 Differs from Rv3378c and Mb3412c by 1aa, A137V in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3760176 11811754 BCGMEX_3447c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172898.1 3759286 R 717522 CDS YP_005172899.1 378773166 11811755 complement(3760185..3761795) 1 NC_016804.1 Differs from Mb3413c by 1aa, T519A, and from Rv3379c by 2aa, T519A and Y196C in BCG Pasteur, BCG Tokyo and BCG Mexico; 1-deoxy-D-xylulose-5-phosphate synthase 3761795 dxs2 11811755 dxs2 Mycobacterium bovis BCG str. Mexico 1-deoxy-D-xylulose-5-phosphate synthase YP_005172899.1 3760185 R 717522 CDS YP_005172900.1 378773167 11811756 complement(3762020..3763009) 1 NC_016804.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3763009 ispH2 11811756 ispH2 Mycobacterium bovis BCG str. Mexico 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_005172900.1 3762020 R 717522 CDS YP_005172901.1 378773168 11811757 complement(3763009..3764061) 1 NC_016804.1 Differs from Rv3383c by 1aa, G132V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative polyprenyl synthetase 3764061 idsB 11811757 idsB Mycobacterium bovis BCG str. Mexico putative polyprenyl synthetase YP_005172901.1 3763009 R 717522 CDS YP_005172902.1 378773169 11811758 complement(3764815..3765207) 1 NC_016804.1 hypothetical protein 3765207 11811758 BCGMEX_3451c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172902.1 3764815 R 717522 CDS YP_005172903.1 378773170 11811759 complement(3765207..3765515) 1 NC_016804.1 hypothetical protein 3765515 11811759 BCGMEX_3452c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172903.1 3765207 R 717522 CDS YP_005172904.1 378773171 11811760 3765664..3766368 1 NC_016804.1 putative transposase 3766368 11811760 BCGMEX_3453 Mycobacterium bovis BCG str. Mexico putative transposase YP_005172904.1 3765664 D 717522 CDS YP_005172905.1 378773172 11811761 3766358..3767035 1 NC_016804.1 putative transposase 3767035 11811761 BCGMEX_3454 Mycobacterium bovis BCG str. Mexico putative transposase YP_005172905.1 3766358 D 717522 CDS YP_005172906.1 378773173 11811762 3767225..3769477 1 NC_016804.1 In Mycobacterium bovis and Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, insertions of 60 bp and 78 bp, and deletions of 75 bp and 9 bp, lead to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (750 aa and 749 aa versus 731 aa). Differs from Mb3420 by 1aa insertion, A205 in BCG Pasteur, BCG Tokyo and BCG Mexico; PE PGRS family protein 3769477 PE_PGRS52 11811762 PE_PGRS52 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005172906.1 3767225 D 717522 CDS YP_005172907.1 378773174 11811763 complement(3769548..3770420) 1 NC_016804.1 Differs from Mb3421c by 1aa, P172L in Mycobacteirum tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative dehydrogenase 3770420 11811763 BCGMEX_3456c Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005172907.1 3769548 R 717522 CDS YP_005172908.1 378773175 11811764 3770494..3771204 1 NC_016804.1 putative lipoprotein 3771204 lpqD 11811764 lpqD Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005172908.1 3770494 D 717522 CDS YP_005172909.1 378773176 11811765 3771250..3773202 1 NC_016804.1 short-chain dehydrogenase 3773202 acrA1 11811765 acrA1 Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005172909.1 3771250 D 717522 CDS YP_005172910.1 378773177 11811766 complement(3773203..3774066) 1 NC_016804.1 Differs from Rv3392c by 1aa, S112N in Mycobacteirum bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; cyclopropane-fatty-acyl-phospholipid synthase 1 3774066 cmaA1 11811766 cmaA1 Mycobacterium bovis BCG str. Mexico cyclopropane-fatty-acyl-phospholipid synthase 1 YP_005172910.1 3773203 R 717522 CDS YP_005172911.1 378773178 11811767 3774090..3775016 1 NC_016804.1 putative nucleoside hydrolase 3775016 iunH 11811767 iunH Mycobacterium bovis BCG str. Mexico putative nucleoside hydrolase YP_005172911.1 3774090 D 717522 CDS YP_005172912.1 378773179 11811768 complement(3775071..3776654) 1 NC_016804.1 hypothetical protein 3776654 11811768 BCGMEX_3461c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172912.1 3775071 R 717522 CDS YP_005172913.1 378773180 11811769 complement(3776651..3777265) 1 NC_016804.1 Differs from Rv3395c by 2aa, V3A, M104V in Mycobacteirum bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3777265 11811769 BCGMEX_3462c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172913.1 3776651 R 717522 CDS YP_005172914.1 378773181 11811770 3777348..3777974 1 NC_016804.1 hypothetical protein 3777974 11811770 BCGMEX_3463 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172914.1 3777348 D 717522 CDS YP_005172915.1 378773182 11811771 complement(3778130..3779707) 1 NC_016804.1 GMP synthase 3779707 guaA 11811771 guaA Mycobacterium bovis BCG str. Mexico GMP synthase YP_005172915.1 3778130 R 717522 CDS YP_005172916.1 378773183 11811772 complement(3779719..3780627) 1 NC_016804.1 putative phytoene synthase 3780627 phyA 11811772 phyA Mycobacterium bovis BCG str. Mexico putative phytoene synthase YP_005172916.1 3779719 R 717522 CDS YP_005172917.1 378773184 11811773 complement(3780656..3781735) 1 NC_016804.1 putative geranylgeranyl pyrophosphate synthase 3781735 idsA1 11811773 idsA1 Mycobacterium bovis BCG str. Mexico putative geranylgeranyl pyrophosphate synthase YP_005172917.1 3780656 R 717522 CDS YP_005172918.1 378773185 11811774 3781758..3782804 1 NC_016804.1 Differs from Rv3399 by 1aa, E330A in Mycobacterium tuberculosis CDC1551, Mycobacteirum bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative S-adenosyl-L-methionine-dependent methyltransferase 3782804 11811774 BCGMEX_3467 Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005172918.1 3781758 D 717522 CDS YP_005172919.1 378773186 11811775 3782868..3783656 1 NC_016804.1 hypothetical protein 3783656 11811775 BCGMEX_3468 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172919.1 3782868 D 717522 CDS YP_005172920.1 378773187 11811776 3783671..3786031 1 NC_016804.1 Differs from Mb3434 by 1aa, R658H in Mycobacterium bovis BCG Pasteur and BCG Mexico, and by 2aa, R658H, R750L in Mycobacterium bovis BCG Tokyo; putative glycosyl hydrolase 3786031 11811776 BCGMEX_3469 Mycobacterium bovis BCG str. Mexico putative glycosyl hydrolase YP_005172920.1 3783671 D 717522 CDS YP_005172921.1 378773188 11811777 complement(3786706..3787758) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transversion leads to a shorter product. Differs from Mb3436c by 1aa, R154C in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3787758 11811777 BCGMEX_3470c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172921.1 3786706 R 717522 CDS YP_005172922.1 378773189 11811778 complement(3788129..3789730) 1 NC_016804.1 hypothetical protein 3789730 11811778 BCGMEX_3471c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172922.1 3788129 R 717522 CDS YP_005172923.1 378773190 11811779 complement(3789747..3790451) 1 NC_016804.1 hypothetical protein 3790451 11811779 BCGMEX_3472c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172923.1 3789747 R 717522 CDS YP_005172924.1 378773191 11811780 complement(3790569..3791135) 1 NC_016804.1 putative transcriptional regulatory protein, TetR family 3791135 11811780 BCGMEX_3473c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR family YP_005172924.1 3790569 R 717522 CDS YP_005172925.1 378773192 11811781 3791197..3792084 1 NC_016804.1 putative dioxygenase 3792084 11811781 BCGMEX_3474 Mycobacterium bovis BCG str. Mexico putative dioxygenase YP_005172925.1 3791197 D 717522 CDS YP_005172926.1 378773193 11811782 3792119..3792418 1 NC_016804.1 hypothetical protein 3792418 11811782 BCGMEX_3475 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172926.1 3792119 D 717522 CDS YP_005172927.1 378773194 11811783 3792415..3792825 1 NC_016804.1 Differs from Rv3408 by 1aa, L46S in Mycobacteirum bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3792825 11811783 BCGMEX_3476 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172927.1 3792415 D 717522 CDS YP_005172928.1 378773195 11811784 complement(3792858..3794594) 1 NC_016804.1 putative cholesterol oxidase 3794594 choD 11811784 choD Mycobacterium bovis BCG str. Mexico putative cholesterol oxidase YP_005172928.1 3792858 R 717522 CDS YP_005172929.1 378773196 11811785 complement(3794650..3795777) 1 NC_016804.1 inosine-5'-monophosphate dehydrogenase 3795777 guaB3 11811785 guaB3 Mycobacterium bovis BCG str. Mexico inosine-5'-monophosphate dehydrogenase YP_005172929.1 3794650 R 717522 CDS YP_005172930.1 378773197 11811786 complement(3795797..3797386) 1 NC_016804.1 inosine-5'-monophosphate dehydrogenase 3797386 guaB2 11811786 guaB2 Mycobacterium bovis BCG str. Mexico inosine-5'-monophosphate dehydrogenase YP_005172930.1 3795797 R 717522 CDS YP_005172931.1 378773198 11811787 3797593..3798003 1 NC_016804.1 hypothetical protein 3798003 11811787 BCGMEX_3480 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172931.1 3797593 D 717522 CDS YP_005172932.1 378773199 11811788 complement(3798013..3798912) 1 NC_016804.1 hypothetical protein 3798912 11811788 BCGMEX_3481c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172932.1 3798013 R 717522 CDS YP_005172933.1 378773200 11811789 complement(3798905..3799543) 1 NC_016804.1 putative RNA polymerase sigma-D factor 3799543 sigD 11811789 sigD Mycobacterium bovis BCG str. Mexico putative RNA polymerase sigma-D factor YP_005172933.1 3798905 R 717522 CDS YP_005172934.1 378773201 11811790 complement(3799561..3800388) 1 NC_016804.1 hypothetical protein 3800388 11811790 BCGMEX_3483c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172934.1 3799561 R 717522 CDS YP_005172935.1 378773202 11811791 3800759..3801067 1 NC_016804.1 transcriptional regulatory protein whiB-like protein 3801067 whiB3 11811791 whiB3 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein whiB-like protein YP_005172935.1 3800759 D 717522 CDS YP_005172936.1 378773203 11811792 complement(3801139..3802758) 1 NC_016804.1 60 kDa chaperonin 2 3802758 groEL2 11811792 groEL2 Mycobacterium bovis BCG str. Mexico 60 kDa chaperonin 2 YP_005172936.1 3801139 R 717522 CDS YP_005172937.1 378773204 11811793 complement(3802853..3803155) 1 NC_016804.1 10 kDa chaperonin 3803155 groES 11811793 groES Mycobacterium bovis BCG str. Mexico 10 kDa chaperonin YP_005172937.1 3802853 R 717522 CDS YP_005172938.1 378773205 11811794 complement(3803422..3804456) 1 NC_016804.1 putative O-sialoglycoprotein endopeptidase 3804456 gcp 11811794 gcp Mycobacterium bovis BCG str. Mexico putative O-sialoglycoprotein endopeptidase YP_005172938.1 3803422 R 717522 CDS YP_005172939.1 378773206 11811795 complement(3804453..3804929) 1 NC_016804.1 ribosomal-protein-alanine acetyltransferase 3804929 rimI 11811795 rimI Mycobacterium bovis BCG str. Mexico ribosomal-protein-alanine acetyltransferase YP_005172939.1 3804453 R 717522 CDS YP_005172940.1 378773207 11811796 complement(3804926..3805561) 1 NC_016804.1 hypothetical protein 3805561 11811796 BCGMEX_3489c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172940.1 3804926 R 717522 CDS YP_005172941.1 378773208 11811797 complement(3805558..3806064) 1 NC_016804.1 hypothetical protein 3806064 11811797 BCGMEX_3490c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172941.1 3805558 R 717522 CDS YP_005172942.1 378773209 11811798 complement(3806061..3807287) 1 NC_016804.1 putative alanine racemase 3807287 alr 11811798 alr Mycobacterium bovis BCG str. Mexico putative alanine racemase YP_005172942.1 3806061 R 717522 CDS YP_005172943.1 378773210 11811799 complement(3807581..3807943) 1 NC_016804.1 hypothetical protein 3807943 11811799 BCGMEX_3492c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172943.1 3807581 R 717522 CDS YP_005172944.1 378773211 11811800 3808106..3808642 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a large deletion of 4926 bp (RD6) leads to the loss of the COOH part of PPE57, and the following CDSs, PPE58, Rv3427c, Rv3428c and the NH2-part of PPE59 compared to Mycobacterium tuberculosis strain H37Rv; PPE family protein 3808642 PPE57 11811800 PPE57 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172944.1 3808106 D 717522 CDS YP_005172945.1 378773212 11811801 complement(3808583..3809746) 1 NC_016804.1 Differs from Mb3460c by 1aa, R233H in Mycobacteirum tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 3809746 11811801 BCGMEX_3494c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172945.1 3808583 R 717522 CDS YP_005172946.1 378773213 11811802 complement(3810235..3811080) 1 NC_016804.1 putative transposase 3811080 11811802 BCGMEX_3495c Mycobacterium bovis BCG str. Mexico putative transposase YP_005172946.1 3810235 R 717522 CDS YP_005172947.1 378773214 11811803 complement(3811313..3812695) 1 NC_016804.1 glutamate decarboxylase 3812695 gadB 11811803 gadB Mycobacterium bovis BCG str. Mexico glutamate decarboxylase YP_005172947.1 3811313 R 717522 CDS YP_005172948.1 378773215 11811804 complement(3812733..3814151) 1 NC_016804.1 Differs from Mb3463c by 1aa, A436 deleted, and from Rv3433c by 2aa, A436 deleted, A442S in Mycobacterium bovis BCG Pasteur and BCG Mexico.Differs from Rv3433c by 1aa, A442S in Mycobacterium bovis BCG Tokyo; hypothetical protein 3814151 11811804 BCGMEX_3497c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172948.1 3812733 R 717522 CDS YP_005172949.1 378773216 11811805 complement(3814153..3814866) 1 NC_016804.1 Differs from Mb3464c by 1aa, A193T in Mycobacteirum tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 3814866 11811805 BCGMEX_3498c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172949.1 3814153 R 717522 CDS YP_005172950.1 378773217 11811806 complement(3814877..3815731) 1 NC_016804.1 putative transmembrane protein 3815731 11811806 BCGMEX_3499c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172950.1 3814877 R 717522 CDS YP_005172951.1 378773218 11811807 complement(3815953..3817827) 1 NC_016804.1 glucosamine--fructose-6-phosphate aminotransferase 3817827 glmS 11811807 glmS Mycobacterium bovis BCG str. Mexico glucosamine--fructose-6-phosphate aminotransferase YP_005172951.1 3815953 R 717522 CDS YP_005172952.1 378773219 11811808 3817849..3818325 1 NC_016804.1 Differs from Rv3437 by 1aa P84L in Mycobacteirum bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 3818325 11811808 BCGMEX_3501 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172952.1 3817849 D 717522 CDS YP_005172953.1 378773220 11811809 3818335..3819177 1 NC_016804.1 hypothetical protein 3819177 11811809 BCGMEX_3502 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172953.1 3818335 D 717522 CDS YP_005172954.1 378773221 11811810 complement(3819197..3820600) 1 NC_016804.1 hypothetical protein 3820600 11811810 BCGMEX_3503c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172954.1 3819197 R 717522 CDS YP_005172955.1 378773222 11811811 complement(3820603..3820914) 1 NC_016804.1 hypothetical protein 3820914 11811811 BCGMEX_3504c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172955.1 3820603 R 717522 CDS YP_005172956.1 378773223 11811812 complement(3820962..3822308) 1 NC_016804.1 phosphoglucosamine mutase 3822308 glmM 11811812 glmM Mycobacterium bovis BCG str. Mexico phosphoglucosamine mutase YP_005172956.1 3820962 R 717522 CDS YP_005172957.1 378773224 11811813 complement(3822433..3822888) 1 NC_016804.1 30S ribosomal protein S9 3822888 rpsI 11811813 rpsI Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S9 YP_005172957.1 3822433 R 717522 CDS YP_005172958.1 378773225 11811814 complement(3822885..3823328) 1 NC_016804.1 50S ribosomal protein L13 3823328 rplM 11811814 rplM Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L13 YP_005172958.1 3822885 R 717522 CDS YP_005172959.1 378773226 11811815 complement(3823561..3823863) 1 NC_016804.1 Esat-6 like protein 3823863 esxT 11811815 esxT Mycobacterium bovis BCG str. Mexico Esat-6 like protein YP_005172959.1 3823561 R 717522 CDS YP_005172960.1 378773227 11811816 complement(3823884..3824261) 1 NC_016804.1 Esat-6 like protein 3824261 esxU 11811816 esxU Mycobacterium bovis BCG str. Mexico Esat-6 like protein YP_005172960.1 3823884 R 717522 CDS YP_005172961.1 378773228 11811817 complement(3824254..3825468) 1 NC_016804.1 hypothetical protein 3825468 11811817 BCGMEX_3510c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172961.1 3824254 R 717522 CDS YP_005172962.1 378773229 11811818 complement(3825465..3829175) 1 NC_016804.1 Differs from Rv3444c by 1 aa, G1082S and Mb3477c by 1 aa G1159S in BCG Pasteur, BCG Tokyo and BCG Mexico; putative ESX-4 secretion system protein 3829175 11811818 BCGMEX_3511c Mycobacterium bovis BCG str. Mexico putative ESX-4 secretion system protein YP_005172962.1 3825465 R 717522 CDS YP_005172963.1 378773230 11811819 3829289..3830692 1 NC_016804.1 Differs from Mb3478 by 1aa A265D in Mycobacteirum tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 3830692 11811819 BCGMEX_3512 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172963.1 3829289 D 717522 CDS YP_005172964.1 378773231 11811820 3830689..3832056 1 NC_016804.1 putative secreted serine protease 3832056 11811820 BCGMEX_3513 Mycobacterium bovis BCG str. Mexico putative secreted serine protease YP_005172964.1 3830689 D 717522 CDS YP_005172965.1 378773232 11811821 complement(3832021..3833433) 1 NC_016804.1 hypothetical protein 3833433 11811821 BCGMEX_3514c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172965.1 3832021 R 717522 CDS YP_005172966.1 378773233 11811822 3833554..3834339 1 NC_016804.1 Differs from Rv3451 and Mb3481 by deletion of 1aa,262R in BCG Pasteur, BCG Tokyo and BCG Mexico; putative cutinase 3834339 cut3 11811822 cut3 Mycobacterium bovis BCG str. Mexico putative cutinase YP_005172966.1 3833554 D 717522 CDS YP_005172967.1 378773234 11811823 3834386..3835066 1 NC_016804.1 putative cutinase 3835066 cut4 11811823 cut4 Mycobacterium bovis BCG str. Mexico putative cutinase YP_005172967.1 3834386 D 717522 CDS YP_005172968.1 378773235 11811824 3835338..3837023 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, Rv3453 and Rv3454 exist as 2 genes. In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base deletion results in a single product that is more similar to Rv3454. Differs from Mb3483 by 1aa, V328I in BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 3837023 11811824 BCGMEX_3517 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005172968.1 3835338 D 717522 CDS YP_005172969.1 378773236 11811825 complement(3836985..3837755) 1 NC_016804.1 tRNA pseudouridine synthase A 3837755 truA 11811825 truA Mycobacterium bovis BCG str. Mexico tRNA pseudouridine synthase A YP_005172969.1 3836985 R 717522 CDS YP_005172970.1 378773237 11811826 complement(3837823..3838365) 1 NC_016804.1 50S ribosomal protein L17 3838365 rplQ 11811826 rplQ Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L17 YP_005172970.1 3837823 R 717522 CDS YP_005172971.1 378773238 11811827 complement(3838397..3839440) 1 NC_016804.1 DNA-directed RNA polymerase subunit alpha 3839440 rpoA 11811827 rpoA Mycobacterium bovis BCG str. Mexico DNA-directed RNA polymerase subunit alpha YP_005172971.1 3838397 R 717522 CDS YP_005172972.1 378773239 11811828 complement(3839591..3840196) 1 NC_016804.1 30S ribosomal protein S4 3840196 rpsD 11811828 rpsD Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S4 YP_005172972.1 3839591 R 717522 CDS YP_005172973.1 378773240 11811829 complement(3840205..3840624) 1 NC_016804.1 Differs from Rv3459c by 1aa, N135K in Mycobacteirum bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 30S ribosomal protein S11 3840624 rpsK 11811829 rpsK Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S11 YP_005172973.1 3840205 R 717522 CDS YP_005172974.1 378773241 11811830 complement(3840628..3841002) 1 NC_016804.1 30S ribosomal protein S13 3841002 rpsM 11811830 rpsM Mycobacterium bovis BCG str. Mexico 30S ribosomal protein S13 YP_005172974.1 3840628 R 717522 CDS YP_005172975.1 378773242 11811831 complement(3841218..3841331) 1 NC_016804.1 50S ribosomal protein L36 3841331 rpmJ 11811831 rpmJ Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L36 YP_005172975.1 3841218 R 717522 CDS YP_005172976.1 378773243 11811832 complement(3841364..3841585) 1 NC_016804.1 translation initiation factor IF-1 3841585 infA 11811832 infA Mycobacterium bovis BCG str. Mexico translation initiation factor IF-1 YP_005172976.1 3841364 R 717522 CDS YP_005172977.1 378773244 11811833 3841839..3842696 1 NC_016804.1 hypothetical protein 3842696 11811833 BCGMEX_3526 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172977.1 3841839 D 717522 CDS YP_005172978.1 378773245 11811834 3842769..3843764 1 NC_016804.1 dTDP-glucose 4,6-dehydratase 3843764 rmlB1 11811834 rmlB1 Mycobacterium bovis BCG str. Mexico dTDP-glucose 4,6-dehydratase YP_005172978.1 3842769 D 717522 CDS YP_005172979.1 378773246 11811835 3843766..3844374 1 NC_016804.1 putative dTDP-4-dehydrorhamnose 3,5-epimerase 3844374 rmlC 11811835 rmlC Mycobacterium bovis BCG str. Mexico putative dTDP-4-dehydrorhamnose 3,5-epimerase YP_005172979.1 3843766 D 717522 CDS YP_005172980.1 378773247 11811836 3844457..3845125 1 NC_016804.1 Differs from Rv3466 by 4aa, T56A, T63A, L91R, I131V in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3845125 11811836 BCGMEX_3529 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172980.1 3844457 D 717522 CDS YP_005172981.1 378773248 11811837 3844896..3845849 1 NC_016804.1 Differs from Rv3467 by 6aa, E134K, G245A, D262G, R275H, K276N, E315K in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3845849 11811837 BCGMEX_3530 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172981.1 3844896 D 717522 CDS YP_005172982.1 378773249 11811838 complement(3845907..3847001) 1 NC_016804.1 Differs from Rv3468c by 1aa, V62I in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative dTDP-glucose 4,6-dehydratase 3847001 rmlB2 11811838 rmlB2 Mycobacterium bovis BCG str. Mexico putative dTDP-glucose 4,6-dehydratase YP_005172982.1 3845907 R 717522 CDS YP_005172983.1 378773250 11811839 complement(3847005..3848015) 1 NC_016804.1 Differs from Rv3469c and Mb3498c by 1aa, G253D in BCG Pasteur, BCG Tokyo and BCG Mexico; 4-hydroxy-2-oxovalerate aldolase 3848015 mhpE 11811839 mhpE Mycobacterium bovis BCG str. Mexico 4-hydroxy-2-oxovalerate aldolase YP_005172983.1 3847005 R 717522 CDS YP_005172984.1 378773251 11811840 complement(3848076..3849734) 1 NC_016804.1 Differs from Mb3499c by 1aa, G421E in Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acetolactate synthase 3849734 ilvB2 11811840 ilvB2 Mycobacterium bovis BCG str. Mexico putative acetolactate synthase YP_005172984.1 3848076 R 717522 CDS YP_005172985.1 378773252 11811841 complement(3849740..3850273) 1 NC_016804.1 Differs from Mb3500c by 1aa, C155W in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3850273 11811841 BCGMEX_3534c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172985.1 3849740 R 717522 CDS YP_005172986.1 378773253 11811842 3850294..3850800 1 NC_016804.1 hypothetical protein 3850800 11811842 BCGMEX_3535 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172986.1 3850294 D 717522 CDS YP_005172987.1 378773254 11811843 complement(3850880..3851665) 1 NC_016804.1 putative peroxidase 3851665 bpoA 11811843 bpoA Mycobacterium bovis BCG str. Mexico putative peroxidase YP_005172987.1 3850880 R 717522 CDS YP_005172988.1 378773255 11811844 complement(3851945..3853294) 1 NC_016804.1 Differs from Rv3476c by 2aa, F81L, V144A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative dicarboxylic acid transport integral membrane protein 3853294 kgtP 11811844 kgtP Mycobacterium bovis BCG str. Mexico putative dicarboxylic acid transport integral membrane protein YP_005172988.1 3851945 R 717522 CDS YP_005172989.1 378773256 11811845 3853667..3853963 1 NC_016804.1 Differs from Rv3477 by 1aa, A26V in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; PE family protein 3853963 PE31 11811845 PE31 Mycobacterium bovis BCG str. Mexico PE family protein YP_005172989.1 3853667 D 717522 CDS YP_005172990.1 378773257 11811846 3854000..3855181 1 NC_016804.1 PPE family protein 3855181 PPE60 11811846 PPE60 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005172990.1 3854000 D 717522 CDS YP_005172991.1 378773258 11811847 3855394..3856695 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv3479 exists as a single gene. In Mycobacterium bovis BCG Pasteur, and BCG Tokyo, BCG Mexico and Mycobacterium bovis, a 713 bp deletion (RD18) splits Rv3479 into 2 parts, Mb3507 and Mb3508. Differs from Rv3479 by 1aa, R174L in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3856695 11811847 BCGMEX_3540 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172991.1 3855394 D 717522 CDS YP_005172992.1 378773259 11811848 3856700..3857746 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv3479 exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a 713 bp deletion (RD18) splits Rv3479 into 2 parts, Mb3507 and Mb3508. Differs from Rv3479 by 1aa, N344T in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3857746 11811848 BCGMEX_3541 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172992.1 3856700 D 717522 CDS YP_005172993.1 378773260 11811849 complement(3857770..3859263) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv (Rv3480c), BCG Pasteur, BCG Tokyo and BCG Mexico exists as a single gene. In Mycobacterium bovis, a frameshift due to a 2 bp deletion splits Rv3480c into 2 parts, Mb3509c and Mb3510c. Differs from Rv3480c and Mb3510c by 1aa, N205D in BCG Pasteur, BCG Tokyo and BCG Mexico; putative diacylglycerol O-acyltransferase 3859263 11811849 BCGMEX_3542c Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005172993.1 3857770 R 717522 CDS YP_005172994.1 378773261 11811850 complement(3859354..3860043) 1 NC_016804.1 putative integral membrane protein 3860043 11811850 BCGMEX_3543c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005172994.1 3859354 R 717522 CDS YP_005172995.1 378773262 11811851 complement(3859478..3860968) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base insertion leads to frameshift and longer product of 496 aa compared to Rv3482c, len: 260 aa; hypothetical protein 3860968 11811851 BCGMEX_3544c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172995.1 3859478 R 717522 CDS YP_005172996.1 378773263 11811852 complement(3861012..3861674) 1 NC_016804.1 hypothetical protein 3861674 11811852 BCGMEX_3545c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172996.1 3861012 R 717522 CDS YP_005172997.1 378773264 11811853 3861940..3863478 1 NC_016804.1 hypothetical protein 3863478 cpsA 11811853 cpsA Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172997.1 3861940 D 717522 CDS YP_005172998.1 378773265 11811854 complement(3863484..3864428) 1 NC_016804.1 Short-chain dehydrogenase/reductase family 3864428 11811854 BCGMEX_3547c Mycobacterium bovis BCG str. Mexico Short-chain dehydrogenase/reductase family YP_005172998.1 3863484 R 717522 CDS YP_005172999.1 378773266 11811855 3864634..3865083 1 NC_016804.1 hypothetical protein 3865083 11811855 BCGMEX_3548 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005172999.1 3864634 D 717522 CDS YP_005173000.1 378773267 11811856 complement(3865036..3865869) 1 NC_016804.1 putative esterase/lipase 3865869 lipF 11811856 lipF Mycobacterium bovis BCG str. Mexico putative esterase/lipase YP_005173000.1 3865036 R 717522 CDS YP_005173001.1 378773268 11811857 3866529..3866852 1 NC_016804.1 Differs from Rv3488 by 1aa, R98G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3866852 11811857 BCGMEX_3550 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173001.1 3866529 D 717522 CDS YP_005173002.1 378773269 11811858 3866934..3867098 1 NC_016804.1 hypothetical protein 3867098 11811858 BCGMEX_3551 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173002.1 3866934 D 717522 CDS YP_005173003.1 378773270 11811859 3867098..3868600 1 NC_016804.1 Differs from Rv3490 by 1aa, L334V in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative alpha,alpha-trehalose-phosphate synthase 3868600 otsA 11811859 otsA Mycobacterium bovis BCG str. Mexico putative alpha,alpha-trehalose-phosphate synthase YP_005173003.1 3867098 D 717522 CDS YP_005173004.1 378773271 11811860 3868752..3869330 1 NC_016804.1 hypothetical protein 3869330 11811860 BCGMEX_3553 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173004.1 3868752 D 717522 CDS YP_005173005.1 378773272 11811861 complement(3869327..3869809) 1 NC_016804.1 putative MCE associated protein 3869809 11811861 BCGMEX_3554c Mycobacterium bovis BCG str. Mexico putative MCE associated protein YP_005173005.1 3869327 R 717522 CDS YP_005173006.1 378773273 11811862 complement(3869809..3870537) 1 NC_016804.1 putative MCE associated alanine and valine rich protein 3870537 11811862 BCGMEX_3555c Mycobacterium bovis BCG str. Mexico putative MCE associated alanine and valine rich protein YP_005173006.1 3869809 R 717522 CDS YP_005173007.1 378773274 11811863 complement(3870537..3872231) 1 NC_016804.1 Differs from Rv3494c by 1aa, G245D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 3872231 mce4F 11811863 mce4F Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005173007.1 3870537 R 717522 CDS YP_005173008.1 378773275 11811864 complement(3872242..3873396) 1 NC_016804.1 putative MCE-family lipoprotein 3873396 lprN 11811864 lprN Mycobacterium bovis BCG str. Mexico putative MCE-family lipoprotein YP_005173008.1 3872242 R 717522 CDS YP_005173009.1 378773276 11811865 complement(3873393..3874748) 1 NC_016804.1 MCE-family protein 3874748 mce4D 11811865 mce4D Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005173009.1 3873393 R 717522 CDS YP_005173010.1 378773277 11811866 complement(3874745..3875818) 1 NC_016804.1 Differs from Mb3527c and Rv3497c by 1aa, P46T in BCG Pasteur, BCG Tokyo and BCG Mexico; MCE-family protein 3875818 mce4C 11811866 mce4C Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005173010.1 3874745 R 717522 CDS YP_005173011.1 378773278 11811867 complement(3875808..3876860) 1 NC_016804.1 MCE-family protein 3876860 mce4B 11811867 mce4B Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005173011.1 3875808 R 717522 CDS YP_005173012.1 378773279 11811868 complement(3876860..3878062) 1 NC_016804.1 MCE-family protein 3878062 mce4A 11811868 mce4A Mycobacterium bovis BCG str. Mexico MCE-family protein YP_005173012.1 3876860 R 717522 CDS YP_005173013.1 378773280 11811869 complement(3878082..3878924) 1 NC_016804.1 putative integral membrane protein 3878924 yrbE4B 11811869 yrbE4B Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005173013.1 3878082 R 717522 CDS YP_005173014.1 378773281 11811870 complement(3878959..3879723) 1 NC_016804.1 putative integral membrane protein 3879723 yrbE4A 11811870 yrbE4A Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005173014.1 3878959 R 717522 CDS YP_005173015.1 378773282 11811871 complement(3879949..3880902) 1 NC_016804.1 putative short-chain type dehydrogenase/reductase 3880902 11811871 BCGMEX_3564c Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase/reductase YP_005173015.1 3879949 R 717522 CDS YP_005173016.1 378773283 11811872 complement(3880927..3881118) 1 NC_016804.1 putative ferredoxin 3881118 fdxD 11811872 fdxD Mycobacterium bovis BCG str. Mexico putative ferredoxin YP_005173016.1 3880927 R 717522 CDS YP_005173017.1 378773284 11811873 3881333..3882535 1 NC_016804.1 putative acyl-CoA dehydrogenase 3882535 fadE26 11811873 fadE26 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173017.1 3881333 D 717522 CDS YP_005173018.1 378773285 11811874 3882560..3883681 1 NC_016804.1 Differs from Rv3505 by 1aa V218A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyl-CoA dehydrogenase 3883681 fadE27 11811874 fadE27 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173018.1 3882560 D 717522 CDS YP_005173019.1 378773286 11811875 3883752..3885260 1 NC_016804.1 putative fatty-acid-CoA synthetase 3885260 fadD17 11811875 fadD17 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA synthetase YP_005173019.1 3883752 D 717522 CDS YP_005173020.1 378773287 11811876 3885431..3889549 1 NC_016804.1 In Mycobacterium bovis, insertions of 18 bp, 72 bp and 9 bp, and deletions of 90 bp, 54 bp and 18 bp, and Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, insertions of 18 bp, 81 bp and 9 bp, and deletions of 90 bp, 27 bp and 18 bp, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (1360 aa and 1372 aa versus 1381 aa). Differs from Mb3537 by 2 insertions of 9aa and 3aa and by 1aa, N599D. Differs from Rv3507 by several insertions, deletions and by 2aa, N599D, G742D in BCG Pasteur and BCG Mexico. Differs from Mb3537 by 2 insertions of 9aa and 3aa in BCG Tokyo. Differs form Rv3507 by several insertions, deletions and by 1aa, G742D in BCG Tokyo.; PE-PGRS family protein 3889549 PE_PGRS53 11811876 PE_PGRS53 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005173020.1 3885431 D 717522 CDS YP_005173021.1 378773288 11811877 3889840..3896124 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, several insertions lead to a longer product compared to its homolog in Mycobacterium bovis (2094 aa in BCG Pasteur and BCG Mexico, and 2055 aa in BCG Tokyo versus 1460 aa). The PE_PGRS54 gene of BCG Tokyo (6153bp) is 132bp shorter than that of BCG Pasteur and BCG Mexico (6285bp). There are two repeats of 465bp in BCG Tokyo and one such repeat in BCG Pasteur and BCG Mexico, as well as three repeats of 552bp in BCG Tokyo and four repeats in BCG Pasteur and BCG Mexico; PE-PGRS family protein 3896124 PE_PGRS54 11811877 PE_PGRS54 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005173021.1 3889840 D 717522 CDS YP_005173022.1 378773289 11811878 complement(3896291..3897838) 1 NC_016804.1 putative acetohydroxyacid synthase 3897838 ilvX 11811878 ilvX Mycobacterium bovis BCG str. Mexico putative acetohydroxyacid synthase YP_005173022.1 3896291 R 717522 CDS YP_005173023.1 378773290 11811879 complement(3897835..3898671) 1 NC_016804.1 hypothetical protein 3898671 11811879 BCGMEX_3572c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173023.1 3897835 R 717522 CDS YP_005173024.1 378773291 11811880 3899031..3904463 1 NC_016804.1 In Mycobacterium tuberculosis H37Rv, PE_PGRS55 and PE_PGRS56 exist as 2 genes. In Mycobacterium bovis, a 344bp insertion results in a single product which is more similar to PE_PGRS55. In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico two deletions of 138bp and 246bp lead to a shorter product compared to its homolog Mycobacterium bovis (1810 aa versus 1938 aa). Also differs from Mb3541 by 3aa, D628A, D743A and D857A. In BCG Tokyo, the PE_PGRS55 gene (5088bp, 1695aa) is 345bp shorter than that of BCG Pasteur and BCG Mexico (5433bp). As 345bp is the length of a repeat in the gene, the difference reflected the copy number of BCG strains; PE-PGRS family protein 3904463 PE_PGRS55 11811880 PE_PGRS55 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005173024.1 3899031 D 717522 CDS YP_005173025.1 378773292 11811881 complement(3904592..3905248) 1 NC_016804.1 putative fatty-acid-CoA ligase 3905248 fadD18 11811881 fadD18 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005173025.1 3904592 R 717522 CDS YP_005173026.1 378773293 11811882 3905294..3908521 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a deletion of 111 bp and an insertion of 360 bp (361bp in BCG Tokyo) lead to a longer product compared to its homolog Mycobacterium bovis. Also differs from Mb3543 by 2aa, S80L and T93A in BCG Pasteur and BCG Mexico; PE-PGRS family protein 3908521 PE_PGRS57 11811882 PE_PGRS57 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005173026.1 3905294 D 717522 CDS YP_005173027.1 378773294 11811883 complement(3909082..3910728) 1 NC_016804.1 putative fatty-acid-CoA ligase 3910728 fadD19 11811883 fadD19 Mycobacterium bovis BCG str. Mexico putative fatty-acid-CoA ligase YP_005173027.1 3909082 R 717522 CDS YP_005173028.1 378773295 11811884 3910802..3911593 1 NC_016804.1 Differs from Rv3516 by 1aa, D86G in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Enoyl-CoA hydratase 3911593 echA19 11811884 echA19 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005173028.1 3910802 D 717522 CDS YP_005173029.1 378773296 11811885 3911689..3912528 1 NC_016804.1 hypothetical protein 3912528 11811885 BCGMEX_3578 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173029.1 3911689 D 717522 CDS YP_005173030.1 378773297 11811886 complement(3912583..3913164) 1 NC_016804.1 putative cytochrome P450 142 3913164 cyp142b 11811886 cyp142b Mycobacterium bovis BCG str. Mexico putative cytochrome P450 142 YP_005173030.1 3912583 R 717522 CDS YP_005173031.1 378773298 11811887 complement(3913161..3913778) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, cyp142 exists as a single gene. In Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion splits cyp142 into 2 parts, cyp142a and cyp142b; putative cytochrome P450 142 3913778 cyp142a 11811887 cyp142a Mycobacterium bovis BCG str. Mexico putative cytochrome P450 142 YP_005173031.1 3913161 R 717522 CDS YP_005173032.1 378773299 11811888 3913807..3914517 1 NC_016804.1 hypothetical protein 3914517 11811888 BCGMEX_3581 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173032.1 3913807 D 717522 CDS YP_005173033.1 378773300 11811889 complement(3914582..3915625) 1 NC_016804.1 putative coenzyme F420-dependent oxidoreductase 3915625 11811889 BCGMEX_3582c Mycobacterium bovis BCG str. Mexico putative coenzyme F420-dependent oxidoreductase YP_005173033.1 3914582 R 717522 CDS YP_005173034.1 378773301 11811890 3915778..3916689 1 NC_016804.1 Differs from Rv3521 by 1aa D295N in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3916689 11811890 BCGMEX_3583 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173034.1 3915778 D 717522 CDS YP_005173035.1 378773302 11811891 3916705..3917769 1 NC_016804.1 Differs from Rv3522 by 1aa I324T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3917769 11811891 BCGMEX_3584 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173035.1 3916705 D 717522 CDS YP_005173036.1 378773303 11811892 3917786..3918970 1 NC_016804.1 acetyl-CoA acetyltransferase 3918970 11811892 BCGMEX_3585 Mycobacterium bovis BCG str. Mexico acetyl-CoA acetyltransferase YP_005173036.1 3917786 D 717522 CDS YP_005173037.1 378773304 11811893 3919012..3920043 1 NC_016804.1 hypothetical protein 3920043 11811893 BCGMEX_3586 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173037.1 3919012 D 717522 CDS YP_005173038.1 378773305 11811894 complement(3920057..3920581) 1 NC_016804.1 putative siderophore-binding protein 3920581 11811894 BCGMEX_3587c Mycobacterium bovis BCG str. Mexico putative siderophore-binding protein YP_005173038.1 3920057 R 717522 CDS YP_005173039.1 378773306 11811895 3920696..3921856 1 NC_016804.1 putative oxidoreductase 3921856 11811895 BCGMEX_3588 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173039.1 3920696 D 717522 CDS YP_005173040.1 378773307 11811896 3921862..3922311 1 NC_016804.1 hypothetical protein 3922311 11811896 BCGMEX_3589 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173040.1 3921862 D 717522 CDS YP_005173041.1 378773308 11811897 complement(3922736..3923449) 1 NC_016804.1 hypothetical protein 3923449 11811897 BCGMEX_3590c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173041.1 3922736 R 717522 CDS YP_005173042.1 378773309 11811898 complement(3924141..3925295) 1 NC_016804.1 hypothetical protein 3925295 11811898 BCGMEX_3591c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173042.1 3924141 R 717522 CDS YP_005173043.1 378773310 11811899 complement(3925295..3926077) 1 NC_016804.1 short-chain dehydrogenase 3926077 11811899 BCGMEX_3592c Mycobacterium bovis BCG str. Mexico short-chain dehydrogenase YP_005173043.1 3925295 R 717522 CDS YP_005173044.1 378773311 11811900 complement(3926074..3927201) 1 NC_016804.1 hypothetical protein 3927201 11811900 BCGMEX_3593c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173044.1 3926074 R 717522 CDS YP_005173045.1 378773312 11811901 3927600..3928820 1 NC_016804.1 PPE family protein 3928820 PPE61 11811901 PPE61 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005173045.1 3927600 D 717522 CDS YP_005173046.1 378773313 11811902 complement(3928962..3930710) 1 NC_016804.1 PPE family protein 3930710 PPE62 11811902 PPE62 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005173046.1 3928962 R 717522 CDS YP_005173047.1 378773314 11811903 complement(3930809..3931849) 1 NC_016804.1 4-hydroxy-2-oxovalerate aldolase 3931849 11811903 BCGMEX_3596c Mycobacterium bovis BCG str. Mexico 4-hydroxy-2-oxovalerate aldolase YP_005173047.1 3930809 R 717522 CDS YP_005173048.1 378773315 11811904 complement(3931846..3932757) 1 NC_016804.1 acetaldehyde dehydrogenase 3932757 11811904 BCGMEX_3597c Mycobacterium bovis BCG str. Mexico acetaldehyde dehydrogenase YP_005173048.1 3931846 R 717522 CDS YP_005173049.1 378773316 11811905 complement(3932768..3933553) 1 NC_016804.1 putative hydratase 3933553 11811905 BCGMEX_3598c Mycobacterium bovis BCG str. Mexico putative hydratase YP_005173049.1 3932768 R 717522 CDS YP_005173050.1 378773317 11811906 3933626..3935317 1 NC_016804.1 3-ketosteroid-delta-1-dehydrogenase 3935317 11811906 BCGMEX_3599 Mycobacterium bovis BCG str. Mexico 3-ketosteroid-delta-1-dehydrogenase YP_005173050.1 3933626 D 717522 CDS YP_005173051.1 378773318 11811907 3935319..3936179 1 NC_016804.1 putative dehydrogenase 3936179 11811907 BCGMEX_3600 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005173051.1 3935319 D 717522 CDS YP_005173052.1 378773319 11811908 3936316..3937755 1 NC_016804.1 PPE family protein 3937755 PPE63 11811908 PPE63 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005173052.1 3936316 D 717522 CDS YP_005173053.1 378773320 11811909 complement(3937756..3938916) 1 NC_016804.1 Lipid-transfer protein 3938916 ltp2 11811909 ltp2 Mycobacterium bovis BCG str. Mexico Lipid-transfer protein YP_005173053.1 3937756 R 717522 CDS YP_005173054.1 378773321 11811910 complement(3938916..3939305) 1 NC_016804.1 hypothetical protein 3939305 11811910 BCGMEX_3603c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173054.1 3938916 R 717522 CDS YP_005173055.1 378773322 11811911 complement(3939302..3940237) 1 NC_016804.1 hypothetical protein 3940237 11811911 BCGMEX_3604c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173055.1 3939302 R 717522 CDS YP_005173056.1 378773323 11811912 complement(3940234..3941397) 1 NC_016804.1 putative acyl-CoA dehydrogenase 3941397 fadE29 11811912 fadE29 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173056.1 3940234 R 717522 CDS YP_005173057.1 378773324 11811913 complement(3941382..3942401) 1 NC_016804.1 putative acyl-CoA dehydrogenase 3942401 fadE28 11811913 fadE28 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173057.1 3941382 R 717522 CDS YP_005173058.1 378773325 11811914 complement(3942401..3943702) 1 NC_016804.1 putative cytochrome P450 125 3943702 cyp125 11811914 cyp125 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 125 YP_005173058.1 3942401 R 717522 CDS YP_005173059.1 378773326 11811915 3943814..3944989 1 NC_016804.1 acetyl-CoA acetyltransferase 3944989 fadA5 11811915 fadA5 Mycobacterium bovis BCG str. Mexico acetyl-CoA acetyltransferase YP_005173059.1 3943814 D 717522 CDS YP_005173060.1 378773327 11811916 3945101..3945556 1 NC_016804.1 hypothetical protein 3945556 11811916 BCGMEX_3609 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173060.1 3945101 D 717522 CDS YP_005173061.1 378773328 11811917 complement(3945639..3946553) 1 NC_016804.1 Differs from Rv3548c by 1aa V218M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative short-chain type dehydrogenase 3946553 11811917 BCGMEX_3610c Mycobacterium bovis BCG str. Mexico putative short-chain type dehydrogenase YP_005173061.1 3945639 R 717522 CDS YP_005173062.1 378773329 11811918 complement(3946576..3947355) 1 NC_016804.1 Short-chain type dehydrogenase 3947355 11811918 BCGMEX_3611c Mycobacterium bovis BCG str. Mexico Short-chain type dehydrogenase YP_005173062.1 3946576 R 717522 CDS YP_005173063.1 378773330 11811919 3947410..3948153 1 NC_016804.1 Enoyl-CoA hydratase 3948153 echA20 11811919 echA20 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase YP_005173063.1 3947410 D 717522 CDS YP_005173064.1 378773331 11811920 3948153..3949031 1 NC_016804.1 Differs from Rv3551 by 1aa, S7A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative CoA-transferase subunit alpha 3949031 11811920 BCGMEX_3613 Mycobacterium bovis BCG str. Mexico putative CoA-transferase subunit alpha YP_005173064.1 3948153 D 717522 CDS YP_005173065.1 378773332 11811921 3949028..3949780 1 NC_016804.1 putative CoA-transferase subunit beta 3949780 11811921 BCGMEX_3614 Mycobacterium bovis BCG str. Mexico putative CoA-transferase subunit beta YP_005173065.1 3949028 D 717522 CDS YP_005173066.1 378773333 11811922 3949878..3950945 1 NC_016804.1 putative oxidoreductase 3950945 11811922 BCGMEX_3615 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173066.1 3949878 D 717522 CDS YP_005173067.1 378773334 11811923 3950942..3952999 1 NC_016804.1 putative electron transfer protein 3952999 fdxB 11811923 fdxB Mycobacterium bovis BCG str. Mexico putative electron transfer protein YP_005173067.1 3950942 D 717522 CDS YP_005173068.1 378773335 11811924 complement(3953087..3953956) 1 NC_016804.1 Differs from Rv3555c by 1aa R268W in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3953956 11811924 BCGMEX_3617c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173068.1 3953087 R 717522 CDS YP_005173069.1 378773336 11811925 complement(3954061..3955221) 1 NC_016804.1 acetyl-CoA acetyltransferase 3955221 fadA6 11811925 fadA6 Mycobacterium bovis BCG str. Mexico acetyl-CoA acetyltransferase YP_005173069.1 3954061 R 717522 CDS YP_005173070.1 378773337 11811926 complement(3955286..3955888) 1 NC_016804.1 putative transcriptional regulatory protein, TetR-family 3955888 11811926 BCGMEX_3619c Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, TetR-family YP_005173070.1 3955286 R 717522 CDS YP_005173071.1 378773338 11811927 3956237..3957895 1 NC_016804.1 PPE family protein 3957895 PPE64 11811927 PPE64 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005173071.1 3956237 D 717522 CDS YP_005173072.1 378773339 11811928 complement(3957904..3958692) 1 NC_016804.1 Differs from Rv3559c by 1aa V222A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 3958692 11811928 BCGMEX_3621c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173072.1 3957904 R 717522 CDS YP_005173073.1 378773340 11811929 complement(3958689..3959846) 1 NC_016804.1 putative acyl-CoA dehydrogenase 3959846 fadE30 11811929 fadE30 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173073.1 3958689 R 717522 CDS YP_005173074.1 378773341 11811930 3959894..3961417 1 NC_016804.1 Differs from Rv3561 by 1aa N405T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Fatty-acid-CoA ligase 3961417 fadD3 11811930 fadD3 Mycobacterium bovis BCG str. Mexico Fatty-acid-CoA ligase YP_005173074.1 3959894 D 717522 CDS YP_005173075.1 378773342 11811931 3961418..3962551 1 NC_016804.1 putative acyl-CoA dehydrogenase 3962551 fadE31 11811931 fadE31 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173075.1 3961418 D 717522 CDS YP_005173076.1 378773343 11811932 3962548..3963507 1 NC_016804.1 Differs from Rv3563 by 2aa R105Q and S275W in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative acyl-CoA dehydrogenase 3963507 fadE32 11811932 fadE32 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173076.1 3962548 D 717522 CDS YP_005173077.1 378773344 11811933 3963504..3964460 1 NC_016804.1 putative acyl-CoA dehydrogenase 3964460 fadE33 11811933 fadE33 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173077.1 3963504 D 717522 CDS YP_005173078.1 378773345 11811934 3964457..3965623 1 NC_016804.1 aspartate aminotransferase 3965623 aspB 11811934 aspB Mycobacterium bovis BCG str. Mexico aspartate aminotransferase YP_005173078.1 3964457 D 717522 CDS YP_005173079.1 378773346 11811935 complement(3965588..3966439) 1 NC_016804.1 arylamine N-acetyltransferase 3966439 nat 11811935 nat Mycobacterium bovis BCG str. Mexico arylamine N-acetyltransferase YP_005173079.1 3965588 R 717522 CDS YP_005173080.1 378773347 11811936 complement(3966424..3966690) 1 NC_016804.1 hypothetical protein 3966690 11811936 BCGMEX_3629c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173080.1 3966424 R 717522 CDS YP_005173081.1 378773348 11811937 complement(3966976..3967539) 1 NC_016804.1 Differs from Rv3567c by 1aa T179I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 3967539 11811937 BCGMEX_3630c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173081.1 3966976 R 717522 CDS YP_005173082.1 378773349 11811938 complement(3967554..3968456) 1 NC_016804.1 Differs from Mb3599c by 1aa Q177R in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative biphenyl-2,3-diol 1,2-dioxygenase 3968456 bphC 11811938 bphC Mycobacterium bovis BCG str. Mexico putative biphenyl-2,3-diol 1,2-dioxygenase YP_005173082.1 3967554 R 717522 CDS YP_005173083.1 378773350 11811939 complement(3968453..3969328) 1 NC_016804.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3969328 bphD 11811939 bphD Mycobacterium bovis BCG str. Mexico 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase YP_005173083.1 3968453 R 717522 CDS YP_005173084.1 378773351 11811940 complement(3969343..3970527) 1 NC_016804.1 Differs from Rv3570c by 1aa D18N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 3970527 11811940 BCGMEX_3633c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173084.1 3969343 R 717522 CDS YP_005173085.1 378773352 11811941 3970674..3971750 1 NC_016804.1 putative hemoglobin-related protein 3971750 hmp 11811941 hmp Mycobacterium bovis BCG str. Mexico putative hemoglobin-related protein YP_005173085.1 3970674 D 717522 CDS YP_005173086.1 378773353 11811942 3971768..3972298 1 NC_016804.1 hypothetical protein 3972298 11811942 BCGMEX_3635 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173086.1 3971768 D 717522 CDS YP_005173087.1 378773354 11811943 complement(3972334..3974469) 1 NC_016804.1 putative acyl-CoA dehydrogenase 3974469 fadE34 11811943 fadE34 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173087.1 3972334 R 717522 CDS YP_005173088.1 378773355 11811944 3974741..3975340 1 NC_016804.1 transcriptional regulatory protein, TetR family 3975340 11811944 BCGMEX_3637 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein, TetR family YP_005173088.1 3974741 D 717522 CDS YP_005173089.1 378773356 11811945 complement(3975346..3976425) 1 NC_016804.1 transcriptional regulatory protein, LacI family 3976425 11811945 BCGMEX_3638c Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein, LacI family YP_005173089.1 3975346 R 717522 CDS YP_005173090.1 378773357 11811946 3976615..3977328 1 NC_016804.1 Differs from Rv3576 by 1aa N118D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 3977328 lppH 11811946 lppH Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005173090.1 3976615 D 717522 CDS YP_005173091.1 378773358 11811947 3977519..3978385 1 NC_016804.1 hypothetical protein 3978385 11811947 BCGMEX_3640 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173091.1 3977519 D 717522 CDS YP_005173092.1 378773359 11811948 3978399..3979640 1 NC_016804.1 Differs from Rv3578 by 1aa S319A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative arsenical pump integral membrane protein 3979640 arsB2 11811948 arsB2 Mycobacterium bovis BCG str. Mexico putative arsenical pump integral membrane protein YP_005173092.1 3978399 D 717522 CDS YP_005173093.1 378773360 11811949 complement(3979682..3980650) 1 NC_016804.1 Differs from Rv3579c by 1aa , A302E in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico. Mb3610c is longer due to frameshift and differs by 1aa V178M in Mycobacterium bovis; putative tRNA/rRNA methyltransferase 3980650 11811949 BCGMEX_3642c Mycobacterium bovis BCG str. Mexico putative tRNA/rRNA methyltransferase YP_005173093.1 3979682 R 717522 CDS YP_005173094.1 378773361 11811950 complement(3980651..3982060) 1 NC_016804.1 cysteinyl-tRNA synthetase 3982060 cysS 11811950 cysS Mycobacterium bovis BCG str. Mexico cysteinyl-tRNA synthetase YP_005173094.1 3980651 R 717522 CDS YP_005173095.1 378773362 11811951 complement(3982125..3982604) 1 NC_016804.1 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 3982604 ispF 11811951 ispF Mycobacterium bovis BCG str. Mexico 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase YP_005173095.1 3982125 R 717522 CDS YP_005173096.1 378773363 11811952 complement(3982601..3983296) 1 NC_016804.1 Differs from Mb3613c by 1aa T92A in Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3983296 ispD 11811952 ispD Mycobacterium bovis BCG str. Mexico 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_005173096.1 3982601 R 717522 CDS YP_005173097.1 378773364 11811953 complement(3983313..3983801) 1 NC_016804.1 transcriptional regulator, CarD family protein 3983801 11811953 BCGMEX_3646c Mycobacterium bovis BCG str. Mexico transcriptional regulator, CarD family protein YP_005173097.1 3983313 R 717522 CDS YP_005173098.1 378773365 11811954 3984086..3984634 1 NC_016804.1 putative lipoprotein 3984634 lpqE 11811954 lpqE Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005173098.1 3984086 D 717522 CDS YP_005173099.1 378773366 11811955 3984700..3986142 1 NC_016804.1 DNA repair protein 3986142 radA 11811955 radA Mycobacterium bovis BCG str. Mexico DNA repair protein YP_005173099.1 3984700 D 717522 CDS YP_005173100.1 378773367 11811956 3986147..3987223 1 NC_016804.1 Differs from Rv3586 by 1 aa, D345E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; DNA integrity scanning protein 3987223 disA 11811956 disA Mycobacterium bovis BCG str. Mexico DNA integrity scanning protein YP_005173100.1 3986147 D 717522 CDS YP_005173101.1 378773368 11811957 complement(3987224..3988015) 1 NC_016804.1 Shorter than Rv3587c and Mb3618c by 1aa, P at 240 in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 3988015 11811957 BCGMEX_3650c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173101.1 3987224 R 717522 CDS YP_005173102.1 378773369 11811958 complement(3988124..3988747) 1 NC_016804.1 Differs from Mb3619c by 1aa I79T in Mycobacterium tuberculosis, BCG Pasteur, BCG Tokyo and BCG Mexico; carbonic anhydrase 3988747 canB 11811958 canB Mycobacterium bovis BCG str. Mexico carbonic anhydrase YP_005173102.1 3988124 R 717522 CDS YP_005173103.1 378773370 11811959 3988746..3989660 1 NC_016804.1 putative adenine glycosylase 3989660 mutY 11811959 mutY Mycobacterium bovis BCG str. Mexico putative adenine glycosylase YP_005173103.1 3988746 D 717522 CDS YP_005173104.1 378773371 11811960 complement(3989657..3991411) 1 NC_016804.1 PE-PGRS family protein 3991411 PE_PGRS58 11811960 PE_PGRS58 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005173104.1 3989657 R 717522 CDS YP_005173105.1 378773372 11811961 complement(3991522..3992295) 1 NC_016804.1 putative hydrolase 3992295 11811961 BCGMEX_3654c Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005173105.1 3991522 R 717522 CDS YP_005173106.1 378773373 11811962 3992310..3992627 1 NC_016804.1 hypothetical protein 3992627 11811962 BCGMEX_3655 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173106.1 3992310 D 717522 CDS YP_005173107.1 378773374 11811963 3992605..3993963 1 NC_016804.1 Differs from Rv3593 by 2 aa, V159A, S186N in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative lipoprotein 3993963 lpqF 11811963 lpqF Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005173107.1 3992605 D 717522 CDS YP_005173108.1 378773375 11811964 3994110..3994937 1 NC_016804.1 hypothetical protein 3994937 11811964 BCGMEX_3657 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173108.1 3994110 D 717522 CDS YP_005173109.1 378773376 11811965 complement(3994851..3996329) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base deletion and a 27bp insertion (*-GCGCGCCGGGGCCACCGTTTCCGCCGG), lead to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis (492 aa versus 439 aa); PE PGRS family protein 3996329 PE_PGRS59 11811965 PE_PGRS59 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005173109.1 3994851 R 717522 CDS YP_005173110.1 378773377 11811966 complement(3996437..3998983) 1 NC_016804.1 putative ATP-dependent Clp protease, ATP-binding subunit 3998983 clpC 11811966 clpC Mycobacterium bovis BCG str. Mexico putative ATP-dependent Clp protease, ATP-binding subunit YP_005173110.1 3996437 R 717522 CDS YP_005173111.1 378773378 11811967 complement(3999260..3999598) 1 NC_016804.1 protein Lsr2 3999598 lsr2 11811967 lsr2 Mycobacterium bovis BCG str. Mexico protein Lsr2 YP_005173111.1 3999260 R 717522 CDS YP_005173112.1 378773379 11811968 complement(3999702..4001219) 1 NC_016804.1 lysyl-tRNA synthetase 4001219 lysS 11811968 lysS Mycobacterium bovis BCG str. Mexico lysyl-tRNA synthetase YP_005173112.1 3999702 R 717522 CDS YP_005173113.1 378773380 11811969 complement(4001320..4002138) 1 NC_016804.1 Pantothenate kinase type III 4002138 11811969 BCGMEX_3662c Mycobacterium bovis BCG str. Mexico Pantothenate kinase type III YP_005173113.1 4001320 R 717522 CDS YP_005173114.1 378773381 11811970 complement(4002141..4002560) 1 NC_016804.1 aspartate 1-decarboxylase 4002560 panD 11811970 panD Mycobacterium bovis BCG str. Mexico aspartate 1-decarboxylase YP_005173114.1 4002141 R 717522 CDS YP_005173115.1 378773382 11811971 complement(4002560..4003489) 1 NC_016804.1 Pantoate--beta-alanine ligase 4003489 panC 11811971 panC Mycobacterium bovis BCG str. Mexico Pantoate--beta-alanine ligase YP_005173115.1 4002560 R 717522 CDS YP_005173116.1 378773383 11811972 complement(4003486..4004397) 1 NC_016804.1 hypothetical protein 4004397 11811972 BCGMEX_3665c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173116.1 4003486 R 717522 CDS YP_005173117.1 378773384 11811973 complement(4004582..4005775) 1 NC_016804.1 Differs from Rv3604c by G153V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein rich in alanine and arginine and proline 4005775 11811973 BCGMEX_3666c Mycobacterium bovis BCG str. Mexico putative transmembrane protein rich in alanine and arginine and proline YP_005173117.1 4004582 R 717522 CDS YP_005173118.1 378773385 11811974 complement(4005984..4006460) 1 NC_016804.1 putative secreted protein 4006460 11811974 BCGMEX_3667c Mycobacterium bovis BCG str. Mexico putative secreted protein YP_005173118.1 4005984 R 717522 CDS YP_005173119.1 378773386 11811975 complement(4006460..4007026) 1 NC_016804.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 4007026 folK 11811975 folK Mycobacterium bovis BCG str. Mexico 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_005173119.1 4006460 R 717522 CDS YP_005173120.1 378773387 11811976 complement(4007023..4007424) 1 NC_016804.1 putative dihydroneopterin aldolase 4007424 folB 11811976 folB Mycobacterium bovis BCG str. Mexico putative dihydroneopterin aldolase YP_005173120.1 4007023 R 717522 CDS YP_005173121.1 378773388 11811977 complement(4007417..4008259) 1 NC_016804.1 dihydropteroate synthase 1 4008259 folP1 11811977 folP1 Mycobacterium bovis BCG str. Mexico dihydropteroate synthase 1 YP_005173121.1 4007417 R 717522 CDS YP_005173122.1 378773389 11811978 complement(4008256..4008864) 1 NC_016804.1 GTP cyclohydrolase I 4008864 folE 11811978 folE Mycobacterium bovis BCG str. Mexico GTP cyclohydrolase I YP_005173122.1 4008256 R 717522 CDS YP_005173123.1 378773390 11811979 complement(4008880..4011162) 1 NC_016804.1 cell division protein ftsH-like protein 4011162 ftsH 11811979 ftsH Mycobacterium bovis BCG str. Mexico cell division protein ftsH-like protein YP_005173123.1 4008880 R 717522 CDS YP_005173124.1 378773391 11811980 4011229..4011882 1 NC_016804.1 similar to Rv3611 in BCG Pasteur and BCG Mexico. In Mycobacterium bovis and BCG Tokyo, a 111bp deletion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis (180 aa versus 217aa); putative arginine and proline rich protein 4011882 11811980 BCGMEX_3673 Mycobacterium bovis BCG str. Mexico putative arginine and proline rich protein YP_005173124.1 4011229 D 717522 CDS YP_005173125.1 378773392 11811981 complement(4011797..4012126) 1 NC_016804.1 hypothetical protein 4012126 11811981 BCGMEX_3674c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173125.1 4011797 R 717522 CDS YP_005173126.1 378773393 11811982 complement(4012160..4012321) 1 NC_016804.1 hypothetical protein 4012321 11811982 BCGMEX_3675c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173126.1 4012160 R 717522 CDS YP_005173127.1 378773394 11811983 complement(4012421..4012975) 1 NC_016804.1 hypothetical protein 4012975 11811983 BCGMEX_3676c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173127.1 4012421 R 717522 CDS YP_005173128.1 378773395 11811984 complement(4013091..4013402) 1 NC_016804.1 hypothetical protein 4013402 11811984 BCGMEX_3677c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173128.1 4013091 R 717522 CDS YP_005173129.1 378773396 11811985 complement(4013476..4014654) 1 NC_016804.1 Differs from Rv3616c by 2aa, V4A, I192T and Mb3646c by 2aa, V4A, V153A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4014654 11811985 BCGMEX_3678c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173129.1 4013476 R 717522 CDS YP_005173130.1 378773397 11811986 4015120..4015635 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a large 5894 bp deletion (RD8) leads to a shorter product with a different NH2 part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (171 aa versus 240 aa); putative lipoprotein 4015635 lpqG 11811986 lpqG Mycobacterium bovis BCG str. Mexico putative lipoprotein YP_005173130.1 4015120 D 717522 CDS YP_005173131.1 378773398 11811987 complement(4015640..4016290) 1 NC_016804.1 hypoxanthine-guanine phosphoribosyltransferase 4016290 hpt 11811987 hpt Mycobacterium bovis BCG str. Mexico hypoxanthine-guanine phosphoribosyltransferase YP_005173131.1 4015640 R 717522 CDS YP_005173132.1 378773399 11811988 complement(4016287..4017258) 1 NC_016804.1 tRNA(Ile)-lysidine synthetase 4017258 tilS 11811988 tilS Mycobacterium bovis BCG str. Mexico tRNA(Ile)-lysidine synthetase YP_005173132.1 4016287 R 717522 CDS YP_005173133.1 378773400 11811989 complement(4017237..4018289) 1 NC_016804.1 hypothetical protein 4018289 11811989 BCGMEX_3682c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173133.1 4017237 R 717522 CDS YP_005173134.1 378773401 11811990 complement(4018286..4019671) 1 NC_016804.1 Differs from Rv3627c by 2 aa, V45A, V81A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4019671 11811990 BCGMEX_3683c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173134.1 4018286 R 717522 CDS YP_005173135.1 378773402 11811991 4019809..4020297 1 NC_016804.1 inorganic pyrophosphatase 4020297 ppa 11811991 ppa Mycobacterium bovis BCG str. Mexico inorganic pyrophosphatase YP_005173135.1 4019809 D 717522 CDS YP_005173136.1 378773403 11811992 complement(4020343..4021440) 1 NC_016804.1 putative integral membrane protein 4021440 11811992 BCGMEX_3685c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005173136.1 4020343 R 717522 CDS YP_005173137.1 378773404 11811993 4021561..4022856 1 NC_016804.1 Differs from Rv3630 by 1aa, T40A in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 4022856 11811993 BCGMEX_3686 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005173137.1 4021561 D 717522 CDS YP_005173138.1 378773405 11811994 4022900..4023625 1 NC_016804.1 putative glycosyl transferase 4023625 11811994 BCGMEX_3687 Mycobacterium bovis BCG str. Mexico putative glycosyl transferase YP_005173138.1 4022900 D 717522 CDS YP_005173139.1 378773406 11811995 4023622..4023966 1 NC_016804.1 hypothetical protein 4023966 11811995 BCGMEX_3688 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173139.1 4023622 D 717522 CDS YP_005173140.1 378773407 11811996 4024177..4025052 1 NC_016804.1 hypothetical protein 4025052 11811996 BCGMEX_3689 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173140.1 4024177 D 717522 CDS YP_005173141.1 378773408 11811997 complement(4025053..4025997) 1 NC_016804.1 UDP-glucose 4-epimerase 4025997 galE1 11811997 galE1 Mycobacterium bovis BCG str. Mexico UDP-glucose 4-epimerase YP_005173141.1 4025053 R 717522 CDS YP_005173142.1 378773409 11811998 4026020..4027795 1 NC_016804.1 putative transmembrane protein 4027795 11811998 BCGMEX_3691 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173142.1 4026020 D 717522 CDS YP_005173143.1 378773410 11811999 4028138..4028485 1 NC_016804.1 putative transposase 4028485 11811999 BCGMEX_3692 Mycobacterium bovis BCG str. Mexico putative transposase YP_005173143.1 4028138 D 717522 CDS YP_005173144.1 378773411 11812000 4028870..4029370 1 NC_016804.1 putative transposase 4029370 11812000 BCGMEX_3693 Mycobacterium bovis BCG str. Mexico putative transposase YP_005173144.1 4028870 D 717522 CDS YP_005173145.1 378773412 11812001 4029370..4030116 1 NC_016804.1 transposase 4030116 11812001 BCGMEX_3694 Mycobacterium bovis BCG str. Mexico transposase YP_005173145.1 4029370 D 717522 CDS YP_005173146.1 378773413 11812002 complement(4030270..4030836) 1 NC_016804.1 Differs from Rv3639c by 1 aa, N53K in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4030836 11812002 BCGMEX_3695c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173146.1 4030270 R 717522 CDS YP_005173147.1 378773414 11812003 complement(4030906..4032135) 1 NC_016804.1 Differs from Rv3640c by 1aa, E296G in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 4032135 11812003 BCGMEX_3696c Mycobacterium bovis BCG str. Mexico putative transposase YP_005173147.1 4030906 R 717522 CDS YP_005173148.1 378773415 11812004 complement(4032311..4032946) 1 NC_016804.1 putative cell filamentation protein 4032946 fic 11812004 fic Mycobacterium bovis BCG str. Mexico putative cell filamentation protein YP_005173148.1 4032311 R 717522 CDS YP_005173149.1 378773416 11812005 complement(4032957..4033151) 1 NC_016804.1 hypothetical protein 4033151 11812005 BCGMEX_3698c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173149.1 4032957 R 717522 CDS YP_005173150.1 378773417 11812006 4033546..4033737 1 NC_016804.1 hypothetical protein 4033737 11812006 BCGMEX_3699 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173150.1 4033546 D 717522 CDS YP_005173151.1 378773418 11812008 complement(4033902..4035107) 1 NC_016804.1 DNA polymerase III subunit delta 4035107 11812008 BCGMEX_3700c Mycobacterium bovis BCG str. Mexico DNA polymerase III subunit delta YP_005173151.1 4033902 R 717522 CDS YP_005173152.1 378773419 11812009 4035193..4036842 1 NC_016804.1 putative transmembrane protein 4036842 11812009 BCGMEX_3701 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173152.1 4035193 D 717522 CDS YP_005173153.1 378773420 11812010 complement(4036839..4039643) 1 NC_016804.1 Differs from Rv3546c and Mb3670c by 1aa, F628L in BCG Pasteur, BCG Tokyo and BCG Mexico; DNA topoisomerase I 4039643 topA 11812010 topA Mycobacterium bovis BCG str. Mexico DNA topoisomerase I YP_005173153.1 4036839 R 717522 CDS YP_005173154.1 378773421 11812011 complement(4039996..4040574) 1 NC_016804.1 hypothetical protein 4040574 11812011 BCGMEX_3703c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173154.1 4039996 R 717522 CDS YP_005173155.1 378773422 11812012 complement(4040714..4040917) 1 NC_016804.1 putative cold shock protein 4040917 cspA 11812012 cspA Mycobacterium bovis BCG str. Mexico putative cold shock protein YP_005173155.1 4040714 R 717522 CDS YP_005173156.1 378773423 11812013 4041167..4043482 1 NC_016804.1 Differs from Rv3649 by 2aa, P93L, D677G, and from Mb3673 by D677G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative helicase 4043482 11812013 BCGMEX_3705 Mycobacterium bovis BCG str. Mexico putative helicase YP_005173156.1 4041167 D 717522 CDS YP_005173157.1 378773424 11812014 4043619..4043903 1 NC_016804.1 PE-PGRS family protein 4043903 PE33 11812014 PE33 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005173157.1 4043619 D 717522 CDS YP_005173158.1 378773425 11812015 4044227..4045264 1 NC_016804.1 hypothetical protein 4045264 11812015 BCGMEX_3707 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173158.1 4044227 D 717522 CDS YP_005173159.1 378773426 11812017 complement(4045779..4046024) 1 NC_016804.1 hypothetical protein 4046024 11812017 BCGMEX_3708c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173159.1 4045779 R 717522 CDS YP_005173160.1 378773427 11812018 4046018..4046332 1 NC_016804.1 PE PGRS family protein 4046332 PE_PGRS60 11812018 PE_PGRS60 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005173160.1 4046018 D 717522 CDS YP_005173161.1 378773428 11812019 4046326..4047021 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, a frameshift due to an in-frame insertion of 126 bp leads to a longer product than in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico. Shorter than Mb3677 due to 18 bp in-frame deletion, removes 6 codons; PE PGRS family protein 4047021 PE_PGRS61 11812019 PE_PGRS61 Mycobacterium bovis BCG str. Mexico PE PGRS family protein YP_005173161.1 4046326 D 717522 CDS YP_005173162.1 378773429 11812020 complement(4047138..4047461) 1 NC_016804.1 hypothetical protein 4047461 11812020 BCGMEX_3711c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173162.1 4047138 R 717522 CDS YP_005173163.1 378773430 11812021 complement(4047478..4047777) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base deletion introducing a premature stop codon, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (99 aa versus 125 aa); hypothetical protein 4047777 11812021 BCGMEX_3712c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173163.1 4047478 R 717522 CDS YP_005173164.1 378773431 11812022 complement(4047801..4048007) 1 NC_016804.1 hypothetical protein 4048007 11812022 BCGMEX_3713c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173164.1 4047801 R 717522 CDS YP_005173165.1 378773432 11812023 complement(4048017..4048592) 1 NC_016804.1 membrane protein 4048592 11812023 BCGMEX_3714c Mycobacterium bovis BCG str. Mexico membrane protein YP_005173165.1 4048017 R 717522 CDS YP_005173166.1 378773433 11812024 complement(4048616..4049416) 1 NC_016804.1 putative transmembrane protein 4049416 11812024 BCGMEX_3715c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173166.1 4048616 R 717522 CDS YP_005173167.1 378773434 11812025 complement(4049413..4050471) 1 NC_016804.1 hypothetical protein 4050471 11812025 BCGMEX_3716c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173167.1 4049413 R 717522 CDS YP_005173168.1 378773435 11812026 complement(4050573..4051625) 1 NC_016804.1 Differs from Rv3660c by 1aa, L30P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4051625 11812026 BCGMEX_3717c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173168.1 4050573 R 717522 CDS YP_005173169.1 378773436 11812027 4052125..4052988 1 NC_016804.1 Differs from Rv3661 by 1aa, P40S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4052988 11812027 BCGMEX_3718 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173169.1 4052125 D 717522 CDS YP_005173170.1 378773437 11812028 complement(4053743..4054513) 1 NC_016804.1 Differs from Rv3662c by 1aa, T34A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4054513 11812028 BCGMEX_3719c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173170.1 4053743 R 717522 CDS YP_005173171.1 378773438 11812029 complement(4054510..4056156) 1 NC_016804.1 putative dipeptide-transport ATP-binding protein ABC transporter 4056156 dppD 11812029 dppD Mycobacterium bovis BCG str. Mexico putative dipeptide-transport ATP-binding protein ABC transporter YP_005173171.1 4054510 R 717522 CDS YP_005173172.1 378773439 11812030 complement(4056153..4056953) 1 NC_016804.1 putative dipeptide-transport integral membrane protein ABC transporter 4056953 dppC 11812030 dppC Mycobacterium bovis BCG str. Mexico putative dipeptide-transport integral membrane protein ABC transporter YP_005173172.1 4056153 R 717522 CDS YP_005173173.1 378773440 11812031 complement(4057009..4057935) 1 NC_016804.1 putative dipeptide-transport integral membrane protein ABC transporter 4057935 dppB 11812031 dppB Mycobacterium bovis BCG str. Mexico putative dipeptide-transport integral membrane protein ABC transporter YP_005173173.1 4057009 R 717522 CDS YP_005173174.1 378773441 11812032 complement(4057937..4059562) 1 NC_016804.1 Differs from Rv3666c by 2aa, R4Q, Q443R and to Mb3690c by 1aa, E451G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative periplasmic dipeptide-binding lipoprotein 4059562 dppA 11812032 dppA Mycobacterium bovis BCG str. Mexico putative periplasmic dipeptide-binding lipoprotein YP_005173174.1 4057937 R 717522 CDS YP_005173175.1 378773442 11812033 4059648..4060004 1 NC_016804.1 hypothetical protein 4060004 11812033 BCGMEX_3724 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173175.1 4059648 D 717522 CDS YP_005173176.1 378773443 11812034 4060270..4062225 1 NC_016804.1 Differs from Mb3691 by 1aa G61E in BCG Pasteur and BCG Mexico; acetyl-CoA synthetase 4062225 acs 11812034 acs Mycobacterium bovis BCG str. Mexico acetyl-CoA synthetase YP_005173176.1 4060270 D 717522 CDS YP_005173177.1 378773444 11812035 complement(4062261..4062959) 1 NC_016804.1 putative protease 4062959 11812035 BCGMEX_3726c Mycobacterium bovis BCG str. Mexico putative protease YP_005173177.1 4062261 R 717522 CDS YP_005173178.1 378773445 11812036 4063305..4063823 1 NC_016804.1 putative transmembrane protein 4063823 11812036 BCGMEX_3727 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173178.1 4063305 D 717522 CDS YP_005173179.1 378773446 11812037 4063824..4064807 1 NC_016804.1 putative epoxide hydrolase 4064807 ephE 11812037 ephE Mycobacterium bovis BCG str. Mexico putative epoxide hydrolase YP_005173179.1 4063824 D 717522 CDS YP_005173180.1 378773447 11812038 complement(4064800..4065993) 1 NC_016804.1 Differs from Rv3671c by 3aa, T165N, L359F, V363I and from Mb3695c by 3aa, T165N and L359F in BCG Pasteur, BCG Tokyo and BCG Mexico; putative membrane-associated serine protease 4065993 11812038 BCGMEX_3729c Mycobacterium bovis BCG str. Mexico putative membrane-associated serine protease YP_005173180.1 4064800 R 717522 CDS YP_005173181.1 378773448 11812039 complement(4065999..4066820) 1 NC_016804.1 hypothetical protein 4066820 11812039 BCGMEX_3730c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173181.1 4065999 R 717522 CDS YP_005173182.1 378773449 11812040 complement(4066952..4067635) 1 NC_016804.1 putative membrane-anchored thioredoxin-like protein 4067635 11812040 BCGMEX_3731c Mycobacterium bovis BCG str. Mexico putative membrane-anchored thioredoxin-like protein YP_005173182.1 4066952 R 717522 CDS YP_005173183.1 378773450 11812041 complement(4067635..4068372) 1 NC_016804.1 endonuclease III 4068372 nth 11812041 nth Mycobacterium bovis BCG str. Mexico endonuclease III YP_005173183.1 4067635 R 717522 CDS YP_005173184.1 378773451 11812042 4068480..4068857 1 NC_016804.1 hypothetical protein 4068857 11812042 BCGMEX_3733 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173184.1 4068480 D 717522 CDS YP_005173185.1 378773452 11812043 4068956..4069630 1 NC_016804.1 Differs from Rv3676 and Mb 3700 by 2aa, P47L, K178E in Mycobacterium bovis BCG Pasteur and BCG Mexico. Differs from Rv3676 and Mb3700 by 2aa, E178K, V184A in Mycobacterium bovis BCG Tokyo; putative transcriptional regulatory protein, crp/fnr-family 4069630 11812043 BCGMEX_3734 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein, crp/fnr-family YP_005173185.1 4068956 D 717522 CDS YP_005173186.1 378773453 11812044 complement(4069736..4070530) 1 NC_016804.1 putative hydrolase 4070530 11812044 BCGMEX_3735c Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005173186.1 4069736 R 717522 CDS YP_005173187.1 378773454 11812045 complement(4070537..4070992) 1 NC_016804.1 hypothetical protein 4070992 11812045 BCGMEX_3736c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173187.1 4070537 R 717522 CDS YP_005173188.1 378773455 11812046 complement(4071008..4071169) 1 NC_016804.1 hypothetical protein 4071169 11812046 BCGMEX_3737c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173188.1 4071008 R 717522 CDS YP_005173189.1 378773456 11812047 4071254..4072276 1 NC_016804.1 putative ATPase 4072276 11812047 BCGMEX_3738 Mycobacterium bovis BCG str. Mexico putative ATPase YP_005173189.1 4071254 D 717522 CDS YP_005173190.1 378773457 11812048 4072273..4073433 1 NC_016804.1 putative anion transporter ATPase 4073433 11812048 BCGMEX_3739 Mycobacterium bovis BCG str. Mexico putative anion transporter ATPase YP_005173190.1 4072273 D 717522 CDS YP_005173191.1 378773458 11812049 complement(4073676..4074032) 1 NC_016804.1 putative transcriptional regulatory protein whiB-like protein 4074032 whiB4 11812049 whiB4 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein whiB-like protein YP_005173191.1 4073676 R 717522 CDS YP_005173192.1 378773459 11812050 4074394..4076826 1 NC_016804.1 Differs from Rv3682 and MT3784 by 1aa, R434G in Mycobacterium bovis BCG Mexico; putative bifunctional membrane-associated penicillin-binding protein 1A/1B 4076826 ponA2 11812050 ponA2 Mycobacterium bovis BCG str. Mexico putative bifunctional membrane-associated penicillin-binding protein 1A/1B YP_005173192.1 4074394 D 717522 CDS YP_005173193.1 378773460 11812051 4076895..4077854 1 NC_016804.1 hypothetical protein 4077854 11812051 BCGMEX_3742 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173193.1 4076895 D 717522 CDS YP_005173194.1 378773461 11812052 4077917..4078957 1 NC_016804.1 putative lyase 4078957 11812052 BCGMEX_3743 Mycobacterium bovis BCG str. Mexico putative lyase YP_005173194.1 4077917 D 717522 CDS YP_005173195.1 378773462 11812054 complement(4079773..4081203) 1 NC_016804.1 Differs from Rv3685c by 1aa, Q136E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative cytochrome P450 137 4081203 cyp137 11812054 cyp137 Mycobacterium bovis BCG str. Mexico putative cytochrome P450 137 YP_005173195.1 4079773 R 717522 CDS YP_005173196.1 378773463 11812055 complement(4081229..4081561) 1 NC_016804.1 hypothetical protein 4081561 11812055 BCGMEX_3745c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173196.1 4081229 R 717522 CDS YP_005173197.1 378773464 11812056 complement(4081801..4082046) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, truncation at the 5' start due to a single base transversion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (81 aa versus 122 aa); hypothetical protein 4082046 11812056 BCGMEX_3746c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173197.1 4081801 R 717522 CDS YP_005173198.1 378773465 11812057 complement(4082371..4082835) 1 NC_016804.1 hypothetical protein 4082835 11812057 BCGMEX_3747c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173198.1 4082371 R 717522 CDS YP_005173199.1 378773466 11812058 4082835..4084190 1 NC_016804.1 Differs from Rv3689 by 1aa, L119V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 4084190 11812058 BCGMEX_3748 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173199.1 4082835 D 717522 CDS YP_005173200.1 378773467 11812059 4084217..4084870 1 NC_016804.1 hypothetical protein 4084870 11812059 BCGMEX_3749 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173200.1 4084217 D 717522 CDS YP_005173201.1 378773468 11812060 4084996..4085997 1 NC_016804.1 hypothetical protein 4085997 11812060 BCGMEX_3750 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173201.1 4084996 D 717522 CDS YP_005173202.1 378773469 11812061 4085994..4087070 1 NC_016804.1 putative methanol dehydrogenase transcriptional regulatory protein 4087070 moxR2 11812061 moxR2 Mycobacterium bovis BCG str. Mexico putative methanol dehydrogenase transcriptional regulatory protein YP_005173202.1 4085994 D 717522 CDS YP_005173203.1 378773470 11812063 4087204..4088526 1 NC_016804.1 membrane protein 4088526 11812063 BCGMEX_3752 Mycobacterium bovis BCG str. Mexico membrane protein YP_005173203.1 4087204 D 717522 CDS YP_005173204.1 378773471 11812064 complement(4088600..4089592) 1 NC_016804.1 putative transmembrane protein 4089592 11812064 BCGMEX_3753c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173204.1 4088600 R 717522 CDS YP_005173205.1 378773472 11812065 4089684..4090616 1 NC_016804.1 membrane protein 4090616 11812065 BCGMEX_3754 Mycobacterium bovis BCG str. Mexico membrane protein YP_005173205.1 4089684 D 717522 CDS YP_005173206.1 378773473 11812066 complement(4090680..4092236) 1 NC_016804.1 In Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, glpK exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion, splits glpK into 2 parts, glpKa and glpKb and removes activity. Differs from Rv3696c by 2aa, A462V and insertion G192, and from Mycobacterium bovis (gplKb) by 1aa G262A; glycerol kinase 4092236 glpK 11812066 glpK Mycobacterium bovis BCG str. Mexico glycerol kinase YP_005173206.1 4090680 R 717522 CDS YP_005173207.1 378773474 11812067 complement(4092286..4092723) 1 NC_016804.1 Differs from Rv3697c by 1aa, R34G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; membrane protein 4092723 11812067 BCGMEX_3756c Mycobacterium bovis BCG str. Mexico membrane protein YP_005173207.1 4092286 R 717522 CDS YP_005173208.1 378773475 11812068 complement(4092720..4092944) 1 NC_016804.1 hypothetical protein 4092944 11812068 BCGMEX_3757c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173208.1 4092720 R 717522 CDS YP_005173209.1 378773476 11812069 4092974..4094503 1 NC_016804.1 Differs from Rv3698 by 3aa, I66M, R233P, A288V and from Mb3724 by 1aa, A288V in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4094503 11812069 BCGMEX_3758 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173209.1 4092974 D 717522 CDS YP_005173210.1 378773477 11812070 4094525..4095226 1 NC_016804.1 hypothetical protein 4095226 11812070 BCGMEX_3759 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173210.1 4094525 D 717522 CDS YP_005173211.1 378773478 11812071 complement(4095229..4096401) 1 NC_016804.1 hypothetical protein 4096401 11812071 BCGMEX_3760c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173211.1 4095229 R 717522 CDS YP_005173212.1 378773479 11812072 complement(4096432..4097397) 1 NC_016804.1 hypothetical protein 4097397 11812072 BCGMEX_3761c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173212.1 4096432 R 717522 CDS YP_005173213.1 378773480 11812073 complement(4097394..4098095) 1 NC_016804.1 hypothetical protein 4098095 11812073 BCGMEX_3762c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173213.1 4097394 R 717522 CDS YP_005173214.1 378773481 11812074 complement(4098095..4099372) 1 NC_016804.1 hypothetical protein 4099372 11812074 BCGMEX_3763c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173214.1 4098095 R 717522 CDS YP_005173215.1 378773482 11812075 complement(4099369..4100667) 1 NC_016804.1 glutamate--cysteine ligase 4100667 gshA 11812075 gshA Mycobacterium bovis BCG str. Mexico glutamate--cysteine ligase YP_005173215.1 4099369 R 717522 CDS YP_005173216.1 378773483 11812076 complement(4100799..4101443) 1 NC_016804.1 hypothetical protein 4101443 11812076 BCGMEX_3765c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173216.1 4100799 R 717522 CDS YP_005173217.1 378773484 11812077 complement(4101572..4101961) 1 NC_016804.1 hypothetical protein 4101961 11812077 BCGMEX_3766c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173217.1 4101572 R 717522 CDS YP_005173218.1 378773485 11812078 complement(4102072..4102392) 1 NC_016804.1 hypothetical protein 4102392 11812078 BCGMEX_3767c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173218.1 4102072 R 717522 CDS YP_005173219.1 378773486 11812079 complement(4102511..4103521) 1 NC_016804.1 hypothetical protein 4103521 11812079 BCGMEX_3768c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173219.1 4102511 R 717522 CDS YP_005173220.1 378773487 11812080 complement(4103661..4104698) 1 NC_016804.1 aspartate-semialdehyde dehydrogenase 4104698 asd 11812080 asd Mycobacterium bovis BCG str. Mexico aspartate-semialdehyde dehydrogenase YP_005173220.1 4103661 R 717522 CDS YP_005173221.1 378773488 11812081 complement(4104699..4105964) 1 NC_016804.1 aspartokinase 4105964 ask 11812081 ask Mycobacterium bovis BCG str. Mexico aspartokinase YP_005173221.1 4104699 R 717522 CDS YP_005173222.1 378773489 11812082 4106221..4108725 1 NC_016804.1 Protein is 190 aa longer than Rv3710, and 57 aalonger than Mb3737 due to differences in copy number of 19codon repeat at 3'-end; 2-isopropylmalate synthase 4108725 leuA 11812082 leuA Mycobacterium bovis BCG str. Mexico 2-isopropylmalate synthase YP_005173222.1 4106221 D 717522 CDS YP_005173223.1 378773490 11812083 complement(4108791..4109780) 1 NC_016804.1 Differs from Rv3711c by 3aa, D76G, A164V, L211V in BCG Pasteur, BCG Tokyo and BCG Mexico; DNA polymerase III subunit epsilon 4109780 dnaQ 11812083 dnaQ Mycobacterium bovis BCG str. Mexico DNA polymerase III subunit epsilon YP_005173223.1 4108791 R 717522 CDS YP_005173224.1 378773491 11812084 4109914..4111155 1 NC_016804.1 Differs from Rv3712 by 2aa, S200G, T351K in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ligase 4111155 11812084 BCGMEX_3773 Mycobacterium bovis BCG str. Mexico putative ligase YP_005173224.1 4109914 D 717522 CDS YP_005173225.1 378773492 11812085 4111160..4111855 1 NC_016804.1 putative cobyric acid synthase 4111855 cobQ2 11812085 cobQ2 Mycobacterium bovis BCG str. Mexico putative cobyric acid synthase YP_005173225.1 4111160 D 717522 CDS YP_005173226.1 378773493 11812086 complement(4111864..4112754) 1 NC_016804.1 hypothetical protein 4112754 11812086 BCGMEX_3775c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173226.1 4111864 R 717522 CDS YP_005173227.1 378773494 11812087 complement(4112822..4113433) 1 NC_016804.1 Recombination protein 4113433 recR 11812087 recR Mycobacterium bovis BCG str. Mexico Recombination protein YP_005173227.1 4112822 R 717522 CDS YP_005173228.1 378773495 11812088 complement(4113445..4113846) 1 NC_016804.1 hypothetical protein 4113846 11812088 BCGMEX_3777c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173228.1 4113445 R 717522 CDS YP_005173229.1 378773496 11812089 4113981..4114706 1 NC_016804.1 hypothetical protein 4114706 11812089 BCGMEX_3778 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173229.1 4113981 D 717522 CDS YP_005173230.1 378773497 11812090 complement(4114748..4115191) 1 NC_016804.1 hypothetical protein 4115191 11812090 BCGMEX_3779c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173230.1 4114748 R 717522 CDS YP_005173231.1 378773498 11812091 4115239..4116651 1 NC_016804.1 Differs from Rv3719 by 1aa, A12T in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4116651 11812091 BCGMEX_3780 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173231.1 4115239 D 717522 CDS YP_005173232.1 378773499 11812092 4116669..4117931 1 NC_016804.1 cyclopropane-fatty-acyl-phospholipid synthase 4117931 11812092 BCGMEX_3781 Mycobacterium bovis BCG str. Mexico cyclopropane-fatty-acyl-phospholipid synthase YP_005173232.1 4116669 D 717522 CDS YP_005173233.1 378773500 11812093 complement(4117928..4119664) 1 NC_016804.1 DNA polymerase III subunits gamma and tau 4119664 dnaZX 11812093 dnaZX Mycobacterium bovis BCG str. Mexico DNA polymerase III subunits gamma and tau YP_005173233.1 4117928 R 717522 CDS YP_005173234.1 378773501 11812094 complement(4119754..4121061) 1 NC_016804.1 Differs from Rv3722c and Mb3749c by 1aa, Y314H in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4121061 11812094 BCGMEX_3783c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173234.1 4119754 R 717522 CDS YP_005173235.1 378773502 11812096 4121469..4122233 1 NC_016804.1 putative transmembrane protein 4122233 11812096 BCGMEX_3784 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173235.1 4121469 D 717522 CDS YP_005173236.1 378773503 11812097 4122400..4123101 1 NC_016804.1 In Mycobacterium tuberculosis, Rv3724A and Rv3724B exist as 2 genes with an overlap region between them. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico a single base deletion leads to a single product; putative cutinase 4123101 cut5 11812097 cut5 Mycobacterium bovis BCG str. Mexico putative cutinase YP_005173236.1 4122400 D 717522 CDS YP_005173237.1 378773504 11812098 4123146..4124147 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base insertion leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis (333 aa versus 309 aa); putative oxidoreductase 4124147 11812098 BCGMEX_3786 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173237.1 4123146 D 717522 CDS YP_005173238.1 378773505 11812099 4124354..4125547 1 NC_016804.1 Differs from Rv3726 by 1aa, S251R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative dehydrogenase 4125547 11812099 BCGMEX_3787 Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005173238.1 4124354 D 717522 CDS YP_005173239.1 378773506 11812100 4125888..4127696 1 NC_016804.1 Differs from Rv3727 by 1aa, M86V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 4127696 11812100 BCGMEX_3788 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173239.1 4125888 D 717522 CDS YP_005173240.1 378773507 11812101 4127806..4131003 1 NC_016804.1 Differs from Rv3728 by 1aa, R464G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative two-domain membrane protein 4131003 11812101 BCGMEX_3789 Mycobacterium bovis BCG str. Mexico putative two-domain membrane protein YP_005173240.1 4127806 D 717522 CDS YP_005173241.1 378773508 11812102 4131218..4133548 1 NC_016804.1 Differs from Rv3729 by 2aa, I170V, S269P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transferase 4133548 11812102 BCGMEX_3790 Mycobacterium bovis BCG str. Mexico putative transferase YP_005173241.1 4131218 D 717522 CDS YP_005173242.1 378773509 11812103 complement(4133613..4134653) 1 NC_016804.1 hypothetical protein 4134653 11812103 BCGMEX_3791c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173242.1 4133613 R 717522 CDS YP_005173243.1 378773510 11812105 4134691..4135767 1 NC_016804.1 Differs from Rv3731 by 1aa, H313R in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ATP-dependent DNA ligase 4135767 ligC 11812105 ligC Mycobacterium bovis BCG str. Mexico ATP-dependent DNA ligase YP_005173243.1 4134691 D 717522 CDS YP_005173244.1 378773511 11812106 4135867..4136925 1 NC_016804.1 hypothetical protein 4136925 11812106 BCGMEX_3793 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173244.1 4135867 D 717522 CDS YP_005173245.1 378773512 11812107 complement(4136945..4137445) 1 NC_016804.1 hypothetical protein 4137445 11812107 BCGMEX_3794c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173245.1 4136945 R 717522 CDS YP_005173246.1 378773513 11812108 complement(4137459..4138823) 1 NC_016804.1 putative diacylglycerol O-acyltransferase 4138823 11812108 BCGMEX_3795c Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005173246.1 4137459 R 717522 CDS YP_005173247.1 378773514 11812109 4139022..4139510 1 NC_016804.1 hypothetical protein 4139510 11812109 BCGMEX_3796 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173247.1 4139022 D 717522 CDS YP_005173248.1 378773515 11812110 4139567..4140628 1 NC_016804.1 Differs from Rv3736 and Mb3763 by 1aa, K76E in BCG Pasteur, BCG Tokyo and BCG Mexico; transcriptional regulatory protein, probably araC/xylS-family 4140628 11812110 BCGMEX_3797 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein, probably araC/xylS-family YP_005173248.1 4139567 D 717522 CDS YP_005173249.1 378773516 11812111 4140632..4142221 1 NC_016804.1 Differs from Rv3737 by 1aa, G40D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 4142221 11812111 BCGMEX_3798 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173249.1 4140632 D 717522 CDS YP_005173250.1 378773517 11812113 complement(4142600..4143946) 1 NC_016804.1 Differs from Rv3740c by 1aa, C422R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative diacylglycerol O-acyltransferase 4143946 11812113 BCGMEX_3800c Mycobacterium bovis BCG str. Mexico putative diacylglycerol O-acyltransferase YP_005173250.1 4142600 R 717522 CDS YP_005173251.1 378773518 11812114 complement(4143946..4144620) 1 NC_016804.1 putative oxidoreductase 4144620 11812114 BCGMEX_3801c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173251.1 4143946 R 717522 CDS YP_005173252.1 378773519 11812115 complement(4144617..4145012) 1 NC_016804.1 putative oxidoreductase 4145012 11812115 BCGMEX_3802c Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173252.1 4144617 R 717522 CDS YP_005173253.1 378773520 11812116 complement(4145158..4147140) 1 NC_016804.1 putative cation transporter P-type ATPase 4147140 ctpJ 11812116 ctpJ Mycobacterium bovis BCG str. Mexico putative cation transporter P-type ATPase YP_005173253.1 4145158 R 717522 CDS YP_005173254.1 378773521 11812117 4147207..4147569 1 NC_016804.1 transcriptional regulatory protein, probably ArsR-family 4147569 11812117 BCGMEX_3804 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein, probably ArsR-family YP_005173254.1 4147207 D 717522 CDS YP_005173255.1 378773522 11812118 complement(4147653..4147865) 1 NC_016804.1 hypothetical protein 4147865 11812118 BCGMEX_3805c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173255.1 4147653 R 717522 CDS YP_005173256.1 378773523 11812119 complement(4147938..4148273) 1 NC_016804.1 putative PE family protein 4148273 PE34 11812119 PE34 Mycobacterium bovis BCG str. Mexico putative PE family protein YP_005173256.1 4147938 R 717522 CDS YP_005173257.1 378773524 11812120 4148491..4148874 1 NC_016804.1 hypothetical protein 4148874 11812120 BCGMEX_3807 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173257.1 4148491 D 717522 CDS YP_005173258.1 378773525 11812121 4149004..4149363 1 NC_016804.1 Differs from Rv3748 by 1aa, D107G in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4149363 11812121 BCGMEX_3808 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173258.1 4149004 D 717522 CDS YP_005173259.1 378773526 11812122 complement(4149396..4149905) 1 NC_016804.1 hypothetical protein 4149905 11812122 BCGMEX_3809c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173259.1 4149396 R 717522 CDS YP_005173260.1 378773527 11812123 complement(4149973..4150365) 1 NC_016804.1 putative excisionase 4150365 11812123 BCGMEX_3810c Mycobacterium bovis BCG str. Mexico putative excisionase YP_005173260.1 4149973 R 717522 CDS YP_005173261.1 378773528 11812124 4150641..4150856 1 NC_016804.1 putative integrase 4150856 11812124 BCGMEX_3811 Mycobacterium bovis BCG str. Mexico putative integrase YP_005173261.1 4150641 D 717522 CDS YP_005173262.1 378773529 11812126 complement(4151014..4151472) 1 NC_016804.1 putative cytidine/deoxycytidylate deaminase 4151472 11812126 BCGMEX_3812c Mycobacterium bovis BCG str. Mexico putative cytidine/deoxycytidylate deaminase YP_005173262.1 4151014 R 717522 CDS YP_005173263.1 378773530 11812127 complement(4151488..4152009) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and Mycobacterium bovis, a single base transition leads to a longer product with a different 5' start compared to its homolog in Mycobacterium tuberculosis strain H37Rv(173 aa versus 166 aa); hypothetical protein 4152009 11812127 BCGMEX_3813c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173263.1 4151488 R 717522 CDS YP_005173264.1 378773531 11812128 4152188..4153093 1 NC_016804.1 prephenate dehydrogenase 4153093 tyrA 11812128 tyrA Mycobacterium bovis BCG str. Mexico prephenate dehydrogenase YP_005173264.1 4152188 D 717522 CDS YP_005173265.1 378773532 11812129 complement(4153056..4153655) 1 NC_016804.1 hypothetical protein 4153655 11812129 BCGMEX_3815c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173265.1 4153056 R 717522 CDS YP_005173266.1 378773533 11812130 complement(4153661..4154380) 1 NC_016804.1 putative osmoprotectant (Glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter 4154380 proZ 11812130 proZ Mycobacterium bovis BCG str. Mexico putative osmoprotectant (Glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter YP_005173266.1 4153661 R 717522 CDS YP_005173267.1 378773534 11812131 complement(4154377..4155066) 1 NC_016804.1 putative osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter 4155066 proW 11812131 proW Mycobacterium bovis BCG str. Mexico putative osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter YP_005173267.1 4154377 R 717522 CDS YP_005173268.1 378773535 11812132 complement(4155054..4156184) 1 NC_016804.1 putative osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport ATP-binding protein ABC transporter 4156184 proV 11812132 proV Mycobacterium bovis BCG str. Mexico putative osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport ATP-binding protein ABC transporter YP_005173268.1 4155054 R 717522 CDS YP_005173269.1 378773536 11812133 complement(4156193..4157140) 1 NC_016804.1 Differs from Rv3759c by 2aa, P85L, V176A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative osmoprotectant (glycine betaine/carnitine/choline/L-proline) binding lipoprotein 4157140 proX 11812133 proX Mycobacterium bovis BCG str. Mexico putative osmoprotectant (glycine betaine/carnitine/choline/L-proline) binding lipoprotein YP_005173269.1 4156193 R 717522 CDS YP_005173270.1 378773537 11812135 4157305..4157607 1 NC_016804.1 hypothetical protein 4157607 11812135 BCGMEX_3820 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173270.1 4157305 D 717522 CDS YP_005173271.1 378773538 11812136 complement(4157629..4158684) 1 NC_016804.1 putative acyl-CoA dehydrogenase 4158684 fadE36 11812136 fadE36 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173271.1 4157629 R 717522 CDS YP_005173272.1 378773539 11812137 complement(4158763..4160643) 1 NC_016804.1 Differs from Rv3762c by 1aa, H345Y and from Mb3788c by 1aa, V161G in BCG Pasteur, BCG Tokyo and BCG Mexico; putative hydrolase 4160643 11812137 BCGMEX_3822c Mycobacterium bovis BCG str. Mexico putative hydrolase YP_005173272.1 4158763 R 717522 CDS YP_005173273.1 378773540 11812138 4160814..4161293 1 NC_016804.1 19 kDa lipoprotein antigen 4161293 lpqH 11812138 lpqH Mycobacterium bovis BCG str. Mexico 19 kDa lipoprotein antigen YP_005173273.1 4160814 D 717522 CDS YP_005173274.1 378773541 11812139 complement(4161349..4162776) 1 NC_016804.1 Differs from Rv3764c by 2aa, R45H, R246C in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Sensor protein 4162776 11812139 BCGMEX_3824c Mycobacterium bovis BCG str. Mexico Sensor protein YP_005173274.1 4161349 R 717522 CDS YP_005173275.1 378773542 11812140 complement(4162847..4163551) 1 NC_016804.1 DNA-binding response regulator 4163551 11812140 BCGMEX_3825c Mycobacterium bovis BCG str. Mexico DNA-binding response regulator YP_005173275.1 4162847 R 717522 CDS YP_005173276.1 378773543 11812141 4164060..4164749 1 NC_016804.1 hypothetical protein 4164749 11812141 BCGMEX_3826 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173276.1 4164060 D 717522 CDS YP_005173277.1 378773544 11812142 complement(4164763..4165707) 1 NC_016804.1 putative S-adenosyl-L-methionine-dependent methyltransferase 4165707 11812142 BCGMEX_3827c Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005173277.1 4164763 R 717522 CDS YP_005173278.1 378773545 11812143 4165837..4166196 1 NC_016804.1 hypothetical protein 4166196 11812143 BCGMEX_3828 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173278.1 4165837 D 717522 CDS YP_005173279.1 378773546 11812144 4166382..4166654 1 NC_016804.1 hypothetical protein 4166654 11812144 BCGMEX_3829 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173279.1 4166382 D 717522 CDS YP_005173280.1 378773547 11812145 complement(4166967..4167542) 1 NC_016804.1 Differs from Rv3770c by 1aa, A98P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative leucine rich protein 4167542 11812145 BCGMEX_3830c Mycobacterium bovis BCG str. Mexico putative leucine rich protein YP_005173280.1 4166967 R 717522 CDS YP_005173281.1 378773548 11812146 complement(4167648..4167830) 1 NC_016804.1 putative remnant of a transposase 4167830 11812146 BCGMEX_3831c Mycobacterium bovis BCG str. Mexico putative remnant of a transposase YP_005173281.1 4167648 R 717522 CDS YP_005173282.1 378773549 11812147 complement(4167845..4168036) 1 NC_016804.1 putative remnant of a transposase 4168036 11812147 BCGMEX_3832c Mycobacterium bovis BCG str. Mexico putative remnant of a transposase YP_005173282.1 4167845 R 717522 CDS YP_005173283.1 378773550 11812148 complement(4168171..4168497) 1 NC_016804.1 hypothetical protein 4168497 11812148 BCGMEX_3833c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173283.1 4168171 R 717522 CDS YP_005173284.1 378773551 11812151 4168901..4169962 1 NC_016804.1 Differs from Rv3772 by 1aa, A142T in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative phenylalanine aminotransferase 4169962 pat 11812151 pat Mycobacterium bovis BCG str. Mexico putative phenylalanine aminotransferase YP_005173284.1 4168901 D 717522 CDS YP_005173285.1 378773552 11812152 complement(4170008..4170352) 1 NC_016804.1 In Mycobacterium tuberculosis Rv3773c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion splits Rv3773c in two parts; hypothetical protein 4170352 11812152 BCGMEX_3835c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173285.1 4170008 R 717522 CDS YP_005173286.1 378773553 11812153 complement(4170357..4170593) 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv, Rv3773c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion splits Rv3773c into 2 parts; hypothetical protein 4170593 11812153 BCGMEX_3836c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173286.1 4170357 R 717522 CDS YP_005173287.1 378773554 11812154 4170617..4171441 1 NC_016804.1 Enoyl-CoA hydratase/isomerase family protein 4171441 echA21 11812154 echA21 Mycobacterium bovis BCG str. Mexico Enoyl-CoA hydratase/isomerase family protein YP_005173287.1 4170617 D 717522 CDS YP_005173288.1 378773555 11812155 4171453..4172700 1 NC_016804.1 putative lipase 4172700 lipE 11812155 lipE Mycobacterium bovis BCG str. Mexico putative lipase YP_005173288.1 4171453 D 717522 CDS YP_005173289.1 378773556 11812156 4172857..4174416 1 NC_016804.1 Differs from Rv3776 by 1aa, V329M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4174416 11812156 BCGMEX_3839 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173289.1 4172857 D 717522 CDS YP_005173290.1 378773557 11812159 4174462..4175448 1 NC_016804.1 Differs from Rv3777 by 1aa, A160V in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative oxidoreductase 4175448 11812159 BCGMEX_3840 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173290.1 4174462 D 717522 CDS YP_005173291.1 378773558 11812161 complement(4175467..4176663) 1 NC_016804.1 putative aminotransferase 4176663 11812161 BCGMEX_3841c Mycobacterium bovis BCG str. Mexico putative aminotransferase YP_005173291.1 4175467 R 717522 CDS YP_005173292.1 378773559 11812162 4176753..4178753 1 NC_016804.1 putative transmembrane protein alanine and leucine rich 4178753 11812162 BCGMEX_3842 Mycobacterium bovis BCG str. Mexico putative transmembrane protein alanine and leucine rich YP_005173292.1 4176753 D 717522 CDS YP_005173293.1 378773560 11812163 4178757..4179293 1 NC_016804.1 hypothetical protein 4179293 11812163 BCGMEX_3843 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173293.1 4178757 D 717522 CDS YP_005173294.1 378773561 11812164 4179297..4180118 1 NC_016804.1 putative O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter 4180118 rbfE 11812164 rbfE Mycobacterium bovis BCG str. Mexico putative O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter YP_005173294.1 4179297 D 717522 CDS YP_005173295.1 378773562 11812165 4180115..4181029 1 NC_016804.1 putative glycosyl transferase 4181029 11812165 BCGMEX_3845 Mycobacterium bovis BCG str. Mexico putative glycosyl transferase YP_005173295.1 4180115 D 717522 CDS YP_005173296.1 378773563 11812166 4181026..4181868 1 NC_016804.1 O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter 4181868 rfbD 11812166 rfbD Mycobacterium bovis BCG str. Mexico O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter YP_005173296.1 4181026 D 717522 CDS YP_005173297.1 378773564 11812167 4182024..4183004 1 NC_016804.1 dTDP-glucose 4,6-dehydratase 4183004 rfbB 11812167 rfbB Mycobacterium bovis BCG str. Mexico dTDP-glucose 4,6-dehydratase YP_005173297.1 4182024 D 717522 CDS YP_005173298.1 378773565 11812168 4183088..4184161 1 NC_016804.1 hypothetical protein 4184161 11812168 BCGMEX_3848 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173298.1 4183088 D 717522 CDS YP_005173299.1 378773566 11812169 complement(4184142..4185365) 1 NC_016804.1 hypothetical protein 4185365 11812169 BCGMEX_3849c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173299.1 4184142 R 717522 CDS YP_005173300.1 378773567 11812170 complement(4185378..4186304) 1 NC_016804.1 putative S-adenosyl-L-methionine-dependent methyltransferase 4186304 11812170 BCGMEX_3850c Mycobacterium bovis BCG str. Mexico putative S-adenosyl-L-methionine-dependent methyltransferase YP_005173300.1 4185378 R 717522 CDS YP_005173301.1 378773568 11812171 4186548..4187033 1 NC_016804.1 hypothetical protein 4187033 11812171 BCGMEX_3851 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173301.1 4186548 D 717522 CDS YP_005173302.1 378773569 11812172 4187142..4187507 1 NC_016804.1 hypothetical protein 4187507 11812172 BCGMEX_3852 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173302.1 4187142 D 717522 CDS YP_005173303.1 378773570 11812173 4187547..4188932 1 NC_016804.1 putative oxidoreductase 4188932 11812173 BCGMEX_3853 Mycobacterium bovis BCG str. Mexico putative oxidoreductase YP_005173303.1 4187547 D 717522 CDS YP_005173304.1 378773571 11812174 4188933..4189697 1 NC_016804.1 putative short-chain dehydrogenase 4189697 11812174 BCGMEX_3854 Mycobacterium bovis BCG str. Mexico putative short-chain dehydrogenase YP_005173304.1 4188933 D 717522 CDS YP_005173305.1 378773572 11812175 4189700..4191631 1 NC_016804.1 putative transmembrane protein 4191631 11812175 BCGMEX_3855 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173305.1 4189700 D 717522 CDS YP_005173306.1 378773573 11812176 4191631..4194915 1 NC_016804.1 Differs from Rv3793 by 1aa, I270T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; integral membrane indolylacetylinositol arabinosyltransferase 4194915 embC 11812176 embC Mycobacterium bovis BCG str. Mexico integral membrane indolylacetylinositol arabinosyltransferase YP_005173306.1 4191631 D 717522 CDS YP_005173307.1 378773574 11812177 4195001..4198285 1 NC_016804.1 putative arabinosyltransferase A 4198285 embA 11812177 embA Mycobacterium bovis BCG str. Mexico putative arabinosyltransferase A YP_005173307.1 4195001 D 717522 CDS YP_005173308.1 378773575 11812178 4198282..4201578 1 NC_016804.1 Differs from Rv3795 by 2aa, S13N, A378E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative arabinosyltransferase B 4201578 embB 11812178 embB Mycobacterium bovis BCG str. Mexico putative arabinosyltransferase B YP_005173308.1 4198282 D 717522 CDS YP_005173309.1 378773576 11812179 4201646..4202773 1 NC_016804.1 Differs from Rv3796 by 1aa, I320T in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4202773 11812179 BCGMEX_3859 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173309.1 4201646 D 717522 CDS YP_005173310.1 378773577 11812180 4202853..4204634 1 NC_016804.1 putative acyl-CoA dehydrogenase 4204634 fadE35 11812180 fadE35 Mycobacterium bovis BCG str. Mexico putative acyl-CoA dehydrogenase YP_005173310.1 4202853 D 717522 CDS YP_005173311.1 378773578 11812181 4204761..4206095 1 NC_016804.1 In Mycobacterium tuberculosis strain H37Rv (Rv3798), Mycobacterium bovis BCG Pasteur (BCG_3860), BCG Tokyo and BCG Mexico, exist as a single gene. In Mycobacterium bovis, a frameshift due to a 11 bp deletion splits Rv3798 into 2 parts, Mb3827 and Mb3828. In Mycobacterium bovis, a frameshift due to a 11 bp deletion splits Rv3798 into 2 parts, Mb3827 and Mb3828; Transposase for insertion sequence element IS1557 4206095 11812181 BCGMEX_3861 Mycobacterium bovis BCG str. Mexico Transposase for insertion sequence element IS1557 YP_005173311.1 4204761 D 717522 CDS YP_005173312.1 378773579 11812182 complement(4206148..4207716) 1 NC_016804.1 propionyl-CoA carboxylase beta chain 4207716 accD4 11812182 accD4 Mycobacterium bovis BCG str. Mexico propionyl-CoA carboxylase beta chain YP_005173312.1 4206148 R 717522 CDS YP_005173313.1 378773580 11812183 complement(4207713..4212914) 1 NC_016804.1 Differs from Rv3800c by 2aa, G523A, N650S and from Mb3829c by 1aa, N650S in BCG Pasteur, BCG Tokyo and BCG Mexico; polyketide synthase 4212914 pks13 11812183 pks13 Mycobacterium bovis BCG str. Mexico polyketide synthase YP_005173313.1 4207713 R 717522 CDS YP_005173314.1 378773581 11812184 complement(4212921..4214834) 1 NC_016804.1 Differs from Rv3801c by 1aa, V523A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Fatty-acid-CoA ligase 4214834 fadD32 11812184 fadD32 Mycobacterium bovis BCG str. Mexico Fatty-acid-CoA ligase YP_005173314.1 4212921 R 717522 CDS YP_005173315.1 378773582 11812185 complement(4215123..4216133) 1 NC_016804.1 hypothetical protein 4216133 11812185 BCGMEX_3865c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173315.1 4215123 R 717522 CDS YP_005173316.1 378773583 11812186 complement(4216331..4217230) 1 NC_016804.1 MPT51/MPB51 antigen 4217230 mpt51 11812186 mpt51 Mycobacterium bovis BCG str. Mexico MPT51/MPB51 antigen YP_005173316.1 4216331 R 717522 CDS YP_005173317.1 378773584 11812187 complement(4217410..4218426) 1 NC_016804.1 antigen 85-A 4218426 fbpA 11812187 fbpA Mycobacterium bovis BCG str. Mexico antigen 85-A YP_005173317.1 4217410 R 717522 CDS YP_005173318.1 378773585 11812188 complement(4218721..4220604) 1 NC_016804.1 Differs from Rv3805c by 1aa, V327I in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 4220604 11812188 BCGMEX_3868c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173318.1 4218721 R 717522 CDS YP_005173319.1 378773586 11812189 complement(4220693..4221601) 1 NC_016804.1 Differs from Rv3806c by 2aa, I49V and D149E, and from Mb3836c by 1aa, I49V in BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 4221601 11812189 BCGMEX_3869c Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005173319.1 4220693 R 717522 CDS YP_005173320.1 378773587 11812190 complement(4221608..4222105) 1 NC_016804.1 putative transmembrane protein 4222105 11812190 BCGMEX_3870c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173320.1 4221608 R 717522 CDS YP_005173321.1 378773588 11812191 complement(4222134..4224047) 1 NC_016804.1 Galactofuranosyl transferase 4224047 11812191 BCGMEX_3871c Mycobacterium bovis BCG str. Mexico Galactofuranosyl transferase YP_005173321.1 4222134 R 717522 CDS YP_005173322.1 378773589 11812192 complement(4224044..4225243) 1 NC_016804.1 UDP-galactopyranose mutase 4225243 glf 11812192 glf Mycobacterium bovis BCG str. Mexico UDP-galactopyranose mutase YP_005173322.1 4224044 R 717522 CDS YP_005173323.1 378773590 11812193 4225507..4226361 1 NC_016804.1 Exported repetitive protein 4226361 pirG 11812193 pirG Mycobacterium bovis BCG str. Mexico Exported repetitive protein YP_005173323.1 4225507 D 717522 CDS YP_005173324.1 378773591 11812194 4226566..4228185 1 NC_016804.1 hypothetical protein 4228185 11812194 BCGMEX_3874 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173324.1 4226566 D 717522 CDS YP_005173325.1 378773592 11812195 4228339..4229853 1 NC_016804.1 PE-PGRS family protein 4229853 PE_PGRS62 11812195 PE_PGRS62 Mycobacterium bovis BCG str. Mexico PE-PGRS family protein YP_005173325.1 4228339 D 717522 CDS YP_005173326.1 378773593 11812196 complement(4230162..4230983) 1 NC_016804.1 Differs from Rv3813c by 1aa, T83M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4230983 11812196 BCGMEX_3876c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173326.1 4230162 R 717522 CDS YP_005173327.1 378773594 11812197 complement(4230998..4231783) 1 NC_016804.1 putative acyltransferase 4231783 11812197 BCGMEX_3877c Mycobacterium bovis BCG str. Mexico putative acyltransferase YP_005173327.1 4230998 R 717522 CDS YP_005173328.1 378773595 11812198 complement(4231801..4232556) 1 NC_016804.1 putative acyltransferase 4232556 11812198 BCGMEX_3878c Mycobacterium bovis BCG str. Mexico putative acyltransferase YP_005173328.1 4231801 R 717522 CDS YP_005173329.1 378773596 11812199 complement(4232560..4233339) 1 NC_016804.1 putative acyltransferase 4233339 11812199 BCGMEX_3879c Mycobacterium bovis BCG str. Mexico putative acyltransferase YP_005173329.1 4232560 R 717522 CDS YP_005173330.1 378773597 11812200 4233415..4234170 1 NC_016804.1 putative phosphotransferase 4234170 11812200 BCGMEX_3880 Mycobacterium bovis BCG str. Mexico putative phosphotransferase YP_005173330.1 4233415 D 717522 CDS YP_005173331.1 378773598 11812201 4234217..4235767 1 NC_016804.1 hypothetical protein 4235767 11812201 BCGMEX_3881 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173331.1 4234217 D 717522 CDS YP_005173332.1 378773599 11812202 4235764..4236099 1 NC_016804.1 hypothetical protein 4236099 11812202 BCGMEX_3882 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173332.1 4235764 D 717522 CDS YP_005173333.1 378773600 11812203 complement(4236187..4237593) 1 NC_016804.1 Differs from Rv3820c by 1aa, I463T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; polyketide synthase associated protein 4237593 papA2 11812203 papA2 Mycobacterium bovis BCG str. Mexico polyketide synthase associated protein YP_005173333.1 4236187 R 717522 CDS YP_005173334.1 378773601 11812204 4237741..4238454 1 NC_016804.1 Differs from Rv3821 by 2aa, N106D, T120A in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative integral membrane protein 4238454 11812204 BCGMEX_3884 Mycobacterium bovis BCG str. Mexico putative integral membrane protein YP_005173334.1 4237741 D 717522 CDS YP_005173335.1 378773602 11812205 4238489..4238857 1 NC_016804.1 Corresponds to Rv3822/Mb3852 but is missing 1bp after codon 122. Differs from Rv3822 by 2aa, Y55C, T103N, in first part (and by 1aa, V92A, in the second part); hypothetical protein 4238857 11812205 BCGMEX_3885 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173335.1 4238489 D 717522 CDS YP_005173336.1 378773603 11812206 4238854..4239702 1 NC_016804.1 Corresponds to 3'-part of Rv3822/Mb3852 due to missing bp after codon 122. Differs from Rv3822 by 1aa, V92A (and by 2aa, Y55C, T105N, in first part); hypothetical protein 4239702 11812206 BCGMEX_3886 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173336.1 4238854 D 717522 CDS YP_005173337.1 378773604 11812207 complement(4240027..4243296) 1 NC_016804.1 Differs from Rv3823c by 2aa, R235G, A526V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; membrane transport protein 4243296 mmpL8 11812207 mmpL8 Mycobacterium bovis BCG str. Mexico membrane transport protein YP_005173337.1 4240027 R 717522 CDS YP_005173338.1 378773605 11812208 complement(4243406..4244941) 1 NC_016804.1 polyketide synthase associated protein 4244941 papA1 11812208 papA1 Mycobacterium bovis BCG str. Mexico polyketide synthase associated protein YP_005173338.1 4243406 R 717522 CDS YP_005173339.1 378773606 11812209 complement(4244992..4251372) 1 NC_016804.1 Differs from Rv3825c and Mb3855c by 1aa, G829V in BCG Pasteur, BCG Tokyo and BCG Mexico; polyketide synthase 4251372 pks2 11812209 pks2 Mycobacterium bovis BCG str. Mexico polyketide synthase YP_005173339.1 4244992 R 717522 CDS YP_005173340.1 378773607 11812211 complement(4252676..4253902) 1 NC_016804.1 Differs from Rv3827c by 1aa, A251T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transposase 4253902 11812211 BCGMEX_3891c Mycobacterium bovis BCG str. Mexico putative transposase YP_005173340.1 4252676 R 717522 CDS YP_005173341.1 378773608 11812212 complement(4253899..4254510) 1 NC_016804.1 putative resolvase 4254510 11812212 BCGMEX_3892c Mycobacterium bovis BCG str. Mexico putative resolvase YP_005173341.1 4253899 R 717522 CDS YP_005173342.1 378773609 11812213 complement(4254511..4256121) 1 NC_016804.1 Differs from Rv3829c by 1aa, D55E in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative dehydrogenase 4256121 11812213 BCGMEX_3893c Mycobacterium bovis BCG str. Mexico putative dehydrogenase YP_005173342.1 4254511 R 717522 CDS YP_005173343.1 378773610 11812214 complement(4256169..4256798) 1 NC_016804.1 transcriptional regulatory protein, TetR family 4256798 11812214 BCGMEX_3894c Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein, TetR family YP_005173343.1 4256169 R 717522 CDS YP_005173344.1 378773611 11812215 4256870..4257352 1 NC_016804.1 hypothetical protein 4257352 11812215 BCGMEX_3895 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173344.1 4256870 D 717522 CDS YP_005173345.1 378773612 11812216 complement(4257349..4257924) 1 NC_016804.1 hypothetical protein 4257924 11812216 BCGMEX_3896c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173345.1 4257349 R 717522 CDS YP_005173346.1 378773613 11812217 4257980..4258771 1 NC_016804.1 Differs from Rv3833 by 1aa, I105V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; transcriptional regulatory protein, AraC family 4258771 11812217 BCGMEX_3897 Mycobacterium bovis BCG str. Mexico transcriptional regulatory protein, AraC family YP_005173346.1 4257980 D 717522 CDS YP_005173347.1 378773614 11812218 complement(4258768..4260027) 1 NC_016804.1 seryl-tRNA synthetase 4260027 serS 11812218 serS Mycobacterium bovis BCG str. Mexico seryl-tRNA synthetase YP_005173347.1 4258768 R 717522 CDS YP_005173348.1 378773615 11812219 4260160..4261518 1 NC_016804.1 Differs from Rv3835 and Mb3865 by 1 aa, Y79N in BCG Pasteur, BCG Tokyo and BCG Mexico, and frameshift due to extra C in C-string that changes C-terminus in BCG Pasteur and BCG Mexico; membrane protein 4261518 11812219 BCGMEX_3899 Mycobacterium bovis BCG str. Mexico membrane protein YP_005173348.1 4260160 D 717522 CDS YP_005173349.1 378773616 11812220 4261515..4261865 1 NC_016804.1 In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base insertion introducing a premature stop codon, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (116 aa versus 137 aa); hypothetical protein 4261865 11812220 BCGMEX_3900 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173349.1 4261515 D 717522 CDS YP_005173350.1 378773617 11812221 complement(4262124..4262822) 1 NC_016804.1 putative phosphoglycerate mutase 4262822 11812221 BCGMEX_3901c Mycobacterium bovis BCG str. Mexico putative phosphoglycerate mutase YP_005173350.1 4262124 R 717522 CDS YP_005173351.1 378773618 11812222 complement(4262819..4263784) 1 NC_016804.1 prephenate dehydratase 4263784 pheA 11812222 pheA Mycobacterium bovis BCG str. Mexico prephenate dehydratase YP_005173351.1 4262819 R 717522 CDS YP_005173352.1 378773619 11812223 4263880..4264656 1 NC_016804.1 Differs from Rv3839 by 1aa, S122P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4264656 11812223 BCGMEX_3903 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173352.1 4263880 D 717522 CDS YP_005173353.1 378773620 11812224 4264682..4265095 1 NC_016804.1 putative transcriptional regulatory protein 4265095 11812224 BCGMEX_3904 Mycobacterium bovis BCG str. Mexico putative transcriptional regulatory protein YP_005173353.1 4264682 D 717522 CDS YP_005173354.1 378773621 11812225 4265293..4265838 1 NC_016804.1 putative bacterioferritin 4265838 bfrB 11812225 bfrB Mycobacterium bovis BCG str. Mexico putative bacterioferritin YP_005173354.1 4265293 D 717522 CDS YP_005173355.1 378773622 11812226 complement(4265853..4266677) 1 NC_016804.1 glycerophosphoryl diester phosphodiesterase 4266677 glpQ1 11812226 glpQ1 Mycobacterium bovis BCG str. Mexico glycerophosphoryl diester phosphodiesterase YP_005173355.1 4265853 R 717522 CDS YP_005173356.1 378773623 11812227 complement(4266683..4267711) 1 NC_016804.1 Differs from Rv3843c by 2aa, R11G, H92R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 4267711 11812227 BCGMEX_3907c Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173356.1 4266683 R 717522 CDS YP_005173357.1 378773624 11812228 complement(4268800..4269012) 1 NC_016804.1 hypothetical protein 4269012 11812228 BCGMEX_3908c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173357.1 4268800 R 717522 CDS YP_005173358.1 378773625 11812229 4269889..4270380 1 NC_016804.1 putative transposase 4270380 11812229 BCGMEX_3909 Mycobacterium bovis BCG str. Mexico putative transposase YP_005173358.1 4269889 D 717522 CDS YP_005173359.1 378773626 11812230 4270395..4270754 1 NC_016804.1 hypothetical protein 4270754 11812230 BCGMEX_3910 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173359.1 4270395 D 717522 CDS YP_005173360.1 378773627 11812231 4271818..4272441 1 NC_016804.1 Differs from Rv3846 by 1aa, T205I in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; Superoxide dismutase 4272441 sodA 11812231 sodA Mycobacterium bovis BCG str. Mexico Superoxide dismutase YP_005173360.1 4271818 D 717522 CDS YP_005173361.1 378773628 11812232 4272652..4273185 1 NC_016804.1 hypothetical protein 4273185 11812232 BCGMEX_3912 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173361.1 4272652 D 717522 CDS YP_005173362.1 378773629 11812233 4273440..4274348 1 NC_016804.1 Differs from Rv3848 by 1aa, I194V in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 4274348 11812233 BCGMEX_3913 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173362.1 4273440 D 717522 CDS YP_005173363.1 378773630 11812234 4274613..4275011 1 NC_016804.1 hypothetical protein 4275011 11812234 BCGMEX_3914 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173363.1 4274613 D 717522 CDS YP_005173364.1 378773631 11812235 4275129..4275785 1 NC_016804.1 hypothetical protein 4275785 11812235 BCGMEX_3915 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173364.1 4275129 D 717522 CDS YP_005173365.1 378773632 11812236 4275797..4276081 1 NC_016804.1 hypothetical protein 4276081 11812236 BCGMEX_3916 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173365.1 4275797 D 717522 CDS YP_005173366.1 378773633 11812237 4276188..4276592 1 NC_016804.1 putative histone-like protein 4276592 hns 11812237 hns Mycobacterium bovis BCG str. Mexico putative histone-like protein YP_005173366.1 4276188 D 717522 CDS YP_005173367.1 378773634 11812238 4276609..4277082 1 NC_016804.1 Regulator of ribonuclease activity A 4277082 rraA 11812238 rraA Mycobacterium bovis BCG str. Mexico Regulator of ribonuclease activity A YP_005173367.1 4276609 D 717522 CDS YP_005173368.1 378773635 11812239 complement(4277118..4278587) 1 NC_016804.1 monooxygenase 4278587 ethA 11812239 ethA Mycobacterium bovis BCG str. Mexico monooxygenase YP_005173368.1 4277118 R 717522 CDS YP_005173369.1 378773636 11812240 4278663..4279313 1 NC_016804.1 transcriptional regulatory repressor protein, TetR family 4279313 ethR 11812240 ethR Mycobacterium bovis BCG str. Mexico transcriptional regulatory repressor protein, TetR family YP_005173369.1 4278663 D 717522 CDS YP_005173370.1 378773637 11812241 complement(4279515..4280522) 1 NC_016804.1 hypothetical protein 4280522 11812241 BCGMEX_3921c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173370.1 4279515 R 717522 CDS YP_005173371.1 378773638 11812242 complement(4280531..4280728) 1 NC_016804.1 hypothetical protein 4280728 11812242 BCGMEX_3922c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173371.1 4280531 R 717522 CDS YP_005173372.1 378773639 11812243 complement(4281153..4282619) 1 NC_016804.1 Differs from Rv3858c by 3aa, N377T, A415D, H423R and from Mb3888c by 2aa N377T and A415D in BCG Pasteur, BCG Tokyo and BCG Mexico; glutamate synthase subunit beta 4282619 gltD 11812243 gltD Mycobacterium bovis BCG str. Mexico glutamate synthase subunit beta YP_005173372.1 4281153 R 717522 CDS YP_005173373.1 378773640 11812244 complement(4282612..4287195) 1 NC_016804.1 Differs from Rv3859c by 1aa, E553Q in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative ferredoxin-dependent glutamate synthase [NADPH] large subunit 4287195 gltB 11812244 gltB Mycobacterium bovis BCG str. Mexico putative ferredoxin-dependent glutamate synthase [NADPH] large subunit YP_005173373.1 4282612 R 717522 CDS YP_005173374.1 378773641 11812245 4287600..4288292 1 NC_016804.1 In Mycobacterium bovis BCG Mexico a deletion leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (230 aa versus 392 aa); hypothetical protein 4288292 11812245 BCGMEX_3925 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173374.1 4287600 D 717522 CDS YP_005173375.1 378773642 11812246 4288535..4289791 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and in Mycobacterium bovis, two in-frame insertion of 36 and 12bp, leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (418 aa versus 402 aa); hypothetical protein 4289791 11812246 BCGMEX_3926 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173375.1 4288535 D 717522 CDS YP_005173376.1 378773643 11812247 4289879..4290190 1 NC_016804.1 ESX-1 secretion-associated protein EspF 4290190 espF 11812247 espF Mycobacterium bovis BCG str. Mexico ESX-1 secretion-associated protein EspF YP_005173376.1 4289879 D 717522 CDS YP_005173377.1 378773644 11812248 4290193..4291044 1 NC_016804.1 ESX-1 secretion-associated protein EspG1 4291044 espG1 11812248 espG1 Mycobacterium bovis BCG str. Mexico ESX-1 secretion-associated protein EspG1 YP_005173377.1 4290193 D 717522 CDS YP_005173378.1 378773645 11812249 4291083..4291634 1 NC_016804.1 ESX-1 secretion-associated protein EspH 4291634 espH 11812249 espH Mycobacterium bovis BCG str. Mexico ESX-1 secretion-associated protein EspH YP_005173378.1 4291083 D 717522 CDS YP_005173379.1 378773646 11812250 4291627..4293348 1 NC_016804.1 Differs from Rv3868 by 1aa, V243A in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ESX-1 secretion system protein EccA1 4293348 eccA1 11812250 eccA1 Mycobacterium bovis BCG str. Mexico ESX-1 secretion system protein EccA1 YP_005173379.1 4291627 D 717522 CDS YP_005173380.1 378773647 11812251 4293352..4294794 1 NC_016804.1 ESX-1 secretion system protein EccB1 4294794 eccB1 11812251 eccB1 Mycobacterium bovis BCG str. Mexico ESX-1 secretion system protein EccB1 YP_005173380.1 4293352 D 717522 CDS YP_005173381.1 378773648 11812252 4294794..4297037 1 NC_016804.1 ESX-1 secretion system protein eccCa1 4297037 eccCa1 11812252 eccCa1 Mycobacterium bovis BCG str. Mexico ESX-1 secretion system protein eccCa1 YP_005173381.1 4294794 D 717522 CDS YP_005173382.1 378773649 11812253 4297140..4298612 1 NC_016804.1 Differs from Rv3871 and Mb3901 by deletion of 101 codons after codon 480 due to BCG-specific RD1 deletion; hypothetical protein 4298612 11812253 BCGMEX_3933 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173382.1 4297140 D 717522 CDS YP_005173383.1 378773650 11812254 complement(4299055..4299402) 1 NC_016804.1 hypothetical protein 4299402 11812254 BCGMEX_3934c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173383.1 4299055 R 717522 CDS YP_005173384.1 378773651 11812255 complement(4299399..4300781) 1 NC_016804.1 Differs from Rv3881c by 7 codon stretch due to 1bp deletion and 1 bp insertion in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4300781 11812255 BCGMEX_3935c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173384.1 4299399 R 717522 CDS YP_005173385.1 378773652 11812256 complement(4300888..4302276) 1 NC_016804.1 ESX-1 secretion system protein EccE1 4302276 eccE1 11812256 eccE1 Mycobacterium bovis BCG str. Mexico ESX-1 secretion system protein EccE1 YP_005173385.1 4300888 R 717522 CDS YP_005173386.1 378773653 11812257 complement(4302273..4303613) 1 NC_016804.1 putative secreted protease 4303613 11812257 BCGMEX_3937c Mycobacterium bovis BCG str. Mexico putative secreted protease YP_005173386.1 4302273 R 717522 CDS YP_005173387.1 378773654 11812258 complement(4303835..4305694) 1 NC_016804.1 Differs from Rv3884c by 1aa, G215E in Mycobacterium tuberculosis CDC1551, Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; Stage V sporulation protein K 4305694 11812258 BCGMEX_3938c Mycobacterium bovis BCG str. Mexico Stage V sporulation protein K YP_005173387.1 4303835 R 717522 CDS YP_005173388.1 378773655 11812259 complement(4305764..4307377) 1 NC_016804.1 Differs from Rv3885c by 1aa, P133L in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; membrane protein 4307377 11812259 BCGMEX_3939c Mycobacterium bovis BCG str. Mexico membrane protein YP_005173388.1 4305764 R 717522 CDS YP_005173389.1 378773656 11812260 complement(4307374..4309026) 1 NC_016804.1 putative secreted alanine and proline rich protease 4309026 11812260 BCGMEX_3940c Mycobacterium bovis BCG str. Mexico putative secreted alanine and proline rich protease YP_005173389.1 4307374 R 717522 CDS YP_005173390.1 378773657 11812261 complement(4309011..4310540) 1 NC_016804.1 SX-2 secretion system protein eccD2 4310540 eccD2 11812261 eccD2 Mycobacterium bovis BCG str. Mexico SX-2 secretion system protein eccD2 YP_005173390.1 4309011 R 717522 CDS YP_005173391.1 378773658 11812262 complement(4310537..4311199) 1 NC_016804.1 Has no counterpart in Mycobacterium bovis owing to deletion of 2405bp; hypothetical protein 4311199 11812262 BCGMEX_3942c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173391.1 4310537 R 717522 CDS YP_005173392.1 378773659 11812263 complement(4311196..4311561) 1 NC_016804.1 Has no counterpart in Mycobacterium bovis owing to deletion of 2405bp; hypothetical protein 4311561 11812263 BCGMEX_3943c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173392.1 4311196 R 717522 CDS YP_005173393.1 378773660 11812264 complement(4311655..4312485) 1 NC_016804.1 In Mycobacterium bovis, a deletion of 2406 bases leads to the loss of the NH2 part of Rv3887c, the entire Rv3888c and the COOH part of Rv3889c compared to Mycobacterium tuberculosis strain H37Rv,Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4312485 11812264 BCGMEX_3944c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173393.1 4311655 R 717522 CDS YP_005173394.1 378773661 11812265 complement(4312493..4312867) 1 NC_016804.1 In Mycobacterium bovis BCG Pasteur, BCG Tokyo, BCG Mexico and in Mycobacterium bovis, a frameshift due to a single base deletion leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (124 aa versus 95 aa); putative EsaT-6 like protein 11 4312867 esxC 11812265 esxC Mycobacterium bovis BCG str. Mexico putative EsaT-6 like protein 11 YP_005173394.1 4312493 R 717522 CDS YP_005173395.1 378773662 11812266 complement(4312903..4313226) 1 NC_016804.1 Differs from Rv3891c by 1aa, A49T in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4313226 esxD 11812266 esxD Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173395.1 4312903 R 717522 CDS YP_005173396.1 378773663 11812267 complement(4313337..4314536) 1 NC_016804.1 Differs from Rv3892c by 2aa, K19T, I206M and from Mb3921c by 1aa I206M in BCG Pasteur, BCG Tokyo and BCG Mexico; PPE family protein 4314536 PPE69 11812267 PPE69 Mycobacterium bovis BCG str. Mexico PPE family protein YP_005173396.1 4313337 R 717522 CDS YP_005173397.1 378773664 11812268 complement(4314615..4314848) 1 NC_016804.1 PE family protein 4314848 PE36 11812268 PE36 Mycobacterium bovis BCG str. Mexico PE family protein YP_005173397.1 4314615 R 717522 CDS YP_005173398.1 378773665 11812269 complement(4315115..4316800) 1 NC_016804.1 In Mycobacterium tuberculosis, Rv3894c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion, splits Rv3894c into 2 parts; membrane protein 4316800 11812269 BCGMEX_3949c Mycobacterium bovis BCG str. Mexico membrane protein YP_005173398.1 4315115 R 717522 CDS YP_005173399.1 378773666 11812270 complement(4316805..4319306) 1 NC_016804.1 In Mycobacterium tuberculosis, Rv3894c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a single base insertion, splits Rv3894c into 2 parts. Differs from first part of Rv3984c by 1aa, P258R in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4319306 11812270 BCGMEX_3950c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173399.1 4316805 R 717522 CDS YP_005173400.1 378773667 11812271 complement(4319307..4320794) 1 NC_016804.1 Differs from Rv3895c by 1aa, G356D in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ESX-2 secretion system protein eccB2 4320794 eccB2 11812271 eccB2 Mycobacterium bovis BCG str. Mexico ESX-2 secretion system protein eccB2 YP_005173400.1 4319307 R 717522 CDS YP_005173401.1 378773668 11812272 complement(4320838..4321704) 1 NC_016804.1 Differs from Rv3896c by 3aa, G83D, V186I, K193Q, and by frameshift due to 1bp deletion leading to shorter product (288 aa versus 302 aa) in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4321704 11812272 BCGMEX_3952c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173401.1 4320838 R 717522 CDS YP_005173402.1 378773669 11812273 complement(4321854..4322843) 1 NC_016804.1 In Mycobacterium tuberculosis, Rv3898c and Rv3897c exist as 2 genes. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transition leads to a single product; hypothetical protein 4322843 11812273 BCGMEX_3953c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173402.1 4321854 R 717522 CDS YP_005173403.1 378773670 11812274 complement(4323005..4323886) 1 NC_016804.1 In Mycobacterium tuberculosis, Rv3899c exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur , BCG Tokyo and BCG Mexico, a frameshift due to a single base deletion splits Rv3899c into 2 parts, Mb3928c and Mb3929c with the former being the more likely product; hypothetical protein 4323886 11812274 BCGMEX_3954c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173403.1 4323005 R 717522 CDS YP_005173404.1 378773671 11812276 complement(4324230..4325165) 1 NC_016804.1 Differs from Rv3900c by 1aa, A18P in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4325165 11812276 BCGMEX_3956c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173404.1 4324230 R 717522 CDS YP_005173405.1 378773672 11812277 complement(4325274..4325669) 1 NC_016804.1 Differs from Rv3901c by 1aa, W21L, and frameshift due to 2bp deletion at 3'-end, and from Mb3931c by frameshift only in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4325669 11812277 BCGMEX_3957c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173405.1 4325274 R 717522 CDS YP_005173406.1 378773673 11812278 complement(4326220..4326750) 1 NC_016804.1 hypothetical protein 4326750 11812278 BCGMEX_3958c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173406.1 4326220 R 717522 CDS YP_005173407.1 378773674 11812279 complement(4326747..4329287) 1 NC_016804.1 hypothetical protein 4329287 11812279 BCGMEX_3959c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173407.1 4326747 R 717522 CDS YP_005173408.1 378773675 11812280 complement(4329292..4329564) 1 NC_016804.1 Differs from Rv3904c by 1aa, V82M in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative ESAT-6-like protein 12 4329564 esxE 11812280 esxE Mycobacterium bovis BCG str. Mexico putative ESAT-6-like protein 12 YP_005173408.1 4329292 R 717522 CDS YP_005173409.1 378773676 11812281 complement(4329713..4329886) 1 NC_016804.1 In Mycobacterium bovis, and Mycobacteium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a single base transition introducing a premature stop codon, leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (57 aa versus 103 aa); putative ESAT-6 like protein 13 4329886 esxF 11812281 esxF Mycobacterium bovis BCG str. Mexico putative ESAT-6 like protein 13 YP_005173409.1 4329713 R 717522 CDS YP_005173410.1 378773677 11812282 complement(4329952..4330461) 1 NC_016804.1 hypothetical protein 4330461 11812282 BCGMEX_3962c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173410.1 4329952 R 717522 CDS YP_005173411.1 378773678 11812283 complement(4330486..4331928) 1 NC_016804.1 poly(A) polymerase 4331928 pcnA 11812283 pcnA Mycobacterium bovis BCG str. Mexico poly(A) polymerase YP_005173411.1 4330486 R 717522 CDS YP_005173412.1 378773679 11812284 4332304..4333050 1 NC_016804.1 putative mutator mutT4 protein 4333050 muT4 11812284 muT4 Mycobacterium bovis BCG str. Mexico putative mutator mutT4 protein YP_005173412.1 4332304 D 717522 CDS YP_005173413.1 378773680 11812285 4333047..4335455 1 NC_016804.1 Differs from Rv3909 by 3aa, R7G, S399N, V538A and from Mb3939 by 1aa G25A in BCG Pasteur, BCG Tokyo and BCG Mexico; hypothetical protein 4335455 11812285 BCGMEX_3965 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173413.1 4333047 D 717522 CDS YP_005173414.1 378773681 11812286 4335452..4339006 1 NC_016804.1 Differs from Rv3910 by 1aa, A480V in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; putative transmembrane protein 4339006 11812286 BCGMEX_3966 Mycobacterium bovis BCG str. Mexico putative transmembrane protein YP_005173414.1 4335452 D 717522 CDS YP_005173415.1 378773682 11812287 4339041..4339631 1 NC_016804.1 In Mycobacterium tuberculosis, sigM exists as a single gene. In Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, a frameshift due to a 2bp to 1bp substitution splits sigM into 2 parts, sigMa and sigMb. Differs from Mb3941 by 1aa A160S in BCG Pasteur, BCG Tokyo and BCG Mexico; RNA polymerase sigma factor 4339631 sigMa 11812287 sigMa Mycobacterium bovis BCG str. Mexico RNA polymerase sigma factor YP_005173415.1 4339041 D 717522 CDS YP_005173416.1 378773683 11812289 4339724..4340488 1 NC_016804.1 hypothetical protein 4340488 11812289 BCGMEX_3969 Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173416.1 4339724 D 717522 CDS YP_005173417.1 378773684 11812290 4340582..4341589 1 NC_016804.1 Differs from Rv3913 by 1aa, G57D in Mycobacterium bovis, BCG Pasteur, BCG Tokyo and BCG Mexico; Thioredoxin reductase 4341589 trxB2 11812290 trxB2 Mycobacterium bovis BCG str. Mexico Thioredoxin reductase YP_005173417.1 4340582 D 717522 CDS YP_005173418.1 378773685 11812291 4341586..4341936 1 NC_016804.1 Thioredoxin 4341936 trxC 11812291 trxC Mycobacterium bovis BCG str. Mexico Thioredoxin YP_005173418.1 4341586 D 717522 CDS YP_005173419.1 378773686 11812292 4342046..4343266 1 NC_016804.1 putative N-acetylmuramoyl-L-alanine amidase 4343266 11812292 BCGMEX_3972 Mycobacterium bovis BCG str. Mexico putative N-acetylmuramoyl-L-alanine amidase YP_005173419.1 4342046 D 717522 CDS YP_005173420.1 378773687 11812293 complement(4343287..4344021) 1 NC_016804.1 hypothetical protein 4344021 11812293 BCGMEX_3973c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173420.1 4343287 R 717522 CDS YP_005173421.1 378773688 11812294 complement(4344311..4345345) 1 NC_016804.1 putative chromosome partitioning protein 4345345 parB 11812294 parB Mycobacterium bovis BCG str. Mexico putative chromosome partitioning protein YP_005173421.1 4344311 R 717522 CDS YP_005173422.1 378773689 11812295 complement(4345342..4346385) 1 NC_016804.1 putative chromosome partitioning protein 4346385 parA 11812295 parA Mycobacterium bovis BCG str. Mexico putative chromosome partitioning protein YP_005173422.1 4345342 R 717522 CDS YP_005173423.1 378773690 11812296 complement(4346382..4347056) 1 NC_016804.1 Differs from Rv3919c by 1aa, F100S in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; ribosomal RNA small subunit methyltransferase G 4347056 rsmG2 11812296 rsmG2 Mycobacterium bovis BCG str. Mexico ribosomal RNA small subunit methyltransferase G YP_005173423.1 4346382 R 717522 CDS YP_005173424.1 378773691 11812297 complement(4347188..4347751) 1 NC_016804.1 Differs from Rv3920c by 1aa, W110R in Mycobacterium bovis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; putative jag protein 4347751 11812297 BCGMEX_3977c Mycobacterium bovis BCG str. Mexico putative jag protein YP_005173424.1 4347188 R 717522 CDS YP_005173425.1 378773692 11812298 complement(4347823..4348923) 1 NC_016804.1 Differs from Rv3921c and Mb3952c by 1aa, V184A in Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico; membrane protein OxaA 4348923 oxaA 11812298 oxaA Mycobacterium bovis BCG str. Mexico membrane protein OxaA YP_005173425.1 4347823 R 717522 CDS YP_005173426.1 378773693 11812299 complement(4348907..4349269) 1 NC_016804.1 hypothetical protein 4349269 11812299 BCGMEX_3979c Mycobacterium bovis BCG str. Mexico hypothetical protein YP_005173426.1 4348907 R 717522 CDS YP_005173427.1 378773694 11812300 complement(4349266..4349643) 1 NC_016804.1 ribonuclease P protein component 4349643 rnpA 11812300 rnpA Mycobacterium bovis BCG str. Mexico ribonuclease P protein component YP_005173427.1 4349266 R 717522 CDS YP_005173428.1 378773695 11812301 complement(4349640..4349783) 1 NC_016804.1 50S ribosomal protein L34 4349783 rpmH 11812301 rpmH Mycobacterium bovis BCG str. Mexico 50S ribosomal protein L34 YP_005173428.1 4349640 R 717522 CDS