-- dump date 20120504_153215 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 340047000001 SEQ_END SEQ_END NC_007633.1 1010023 1010023 DR NC_007633.1; contig end 1010023..1010023 Mycoplasma capricolum subsp. capricolum ATCC 27343 YP_424001.1 CDS dnaA NC_007633.1 1 1353 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1..1353 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828310 YP_424002.1 CDS dnaN NC_007633.1 1518 2645 D identified by similarity to SP:P05649; match to protein family HMM PF00712; match to protein family HMM PF02767; match to protein family HMM PF02768; match to protein family HMM TIGR00663; DNA polymerase III subunit beta 1518..2645 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829107 YP_424003.1 CDS MCAP_0003 NC_007633.1 2682 3224 D identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; primase-like protein 2682..3224 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828721 YP_424004.1 CDS ksgA NC_007633.1 3214 4014 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 3214..4014 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828432 YP_424005.1 CDS MCAP_0005 NC_007633.1 4069 5163 D MCAP_0005 has 3 membrane spanning regions; hypothetical protein 4069..5163 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828561 YP_424006.1 CDS MCAP_0007 NC_007633.1 5328 5771 D identified by match to protein family HMM PF00383; cytidine/deoxycytidylate deaminase zinc-binding domain-containing protein 5328..5771 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828443 YP_424007.1 CDS dnaX NC_007633.1 5851 7860 D identified by similarity to SP:P09122; match to protein family HMM PF00004; match to protein family HMM TIGR02397; DNA polymerase III subunits gamma/tau 5851..7860 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828328 YP_424008.1 CDS recM NC_007633.1 7862 8452 D identified by similarity to SP:P24277; match to protein family HMM PF01751; DNA repair protein RecM 7862..8452 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829093 YP_424009.1 CDS tmk NC_007633.1 8455 9096 D identified by similarity to SP:P37537; match to protein family HMM PF02223; match to protein family HMM TIGR00041; thymidylate kinase 8455..9096 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828798 YP_424010.1 CDS MCAP_0011 NC_007633.1 9074 9817 D identified by similarity to SP:P37540; DNA polymerase III, delta prime subunit 9074..9817 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829033 YP_424011.1 CDS MCAP_0012 NC_007633.1 9877 10539 D N-6 adenine-specific DNA methylases 9877..10539 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828574 YP_424012.1 CDS MCAP_0013 NC_007633.1 10590 11411 D This protein has some homology to RpiR family transcriptional regulators.; hypothetical protein 10590..11411 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828948 YP_424013.1 CDS MCAP_0014 NC_007633.1 11416 12621 D This family of proteins belongs to the PP-loop superfamily (MEDLINE:7731953) for which no biological role has been determined; identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; hypothetical protein 11416..12621 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828851 YP_424014.1 CDS MCAP_0015 NC_007633.1 12618 13454 R hypothetical protein complement(12618..13454) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828325 YP_424015.1 CDS ftsH NC_007633.1 13687 15639 D identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; ATP-dependent metalloprotease FtsH 13687..15639 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828957 YP_424016.1 CDS MCAP_0018 NC_007633.1 16712 22105 R MCAP_0018 has 8 membrane spanning regions; MCAP_0018 has characteristics of an ABC transporter permease; however it is not near any ATPase; identified by match to protein family HMM PF02687; hypothetical protein complement(16712..22105) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828921 YP_424017.1 CDS MCAP_0019 NC_007633.1 22249 25407 D MCAP_0019 has 1 membrane spanning region, N-terminal; hypothetical protein 22249..25407 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828911 YP_424018.1 CDS hslO NC_007633.1 25583 26449 D identified by match to protein family HMM PF01430; chaperonin HSP33 25583..26449 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828607 YP_424019.1 CDS MCAP_0021 NC_007633.1 26497 27534 D This gene is not part of any apparent ABC trasporter cassette. The start site confidence is low; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 26497..27534 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828364 YP_424020.1 CDS MCAP_0022 NC_007633.1 27586 28185 R identified by similarity to SP:P41407; match to protein family HMM PF02525; azoreductase complement(27586..28185) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828557 YP_424021.1 CDS MCAP_0023 NC_007633.1 28374 28580 D identified by similarity to SP:P15277; match to protein family HMM PF00313; cold shock protein 28374..28580 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828305 YP_424022.1 CDS rpsF NC_007633.1 28783 29196 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 28783..29196 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828461 YP_424023.1 CDS ssb NC_007633.1 29212 29652 D identified by similarity to SP:P37455; match to protein family HMM PF00436; match to protein family HMM PF01336; match to protein family HMM TIGR00621; single-strand DNA-binding protein 29212..29652 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828457 YP_424024.1 CDS rpsR NC_007633.1 29671 29898 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 29671..29898 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829110 YP_424025.1 CDS MCAP_0027 NC_007633.1 30594 31982 D Similar genes in other organisms are annotated as ATP-dependent DNA helicase recG; however this gene has insufficient similarity to any characterized protein to make that annotation. The ortholog in M, mycoides SC is disrupted; identified by match to protein family HMM PF04326; hypothetical protein 30594..31982 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828816 YP_424026.1 CDS MCAP_0028 NC_007633.1 32257 33810 D The Bacillus stearothermophilus MtlA protein was characterized and is 38% identical to this gene; identified by similarity to SP:P50852; match to protein family HMM PF02302; PTS system mannitol-specific transporter subunit IIBC 32257..33810 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828486 YP_424027.1 CDS MCAP_0029 NC_007633.1 33810 34568 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 33810..34568 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828789 YP_424028.1 CDS MCAP_0030 NC_007633.1 34568 34813 D identified by similarity to SP:Q45420; PTS system mannitol-specific transporter subunit IIA 34568..34813 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828683 YP_424029.1 CDS MCAP_0031 NC_007633.1 35027 35824 D This is a weak hit to the rpiR transcriptional regulator family. The gene is adjacent to mannitol specific PTS system genes and genes for manitol metabolism; identified by similarity to SP:P37767; match to protein family HMM PF01380; RpiR family phosphosugar-binding transcriptional regulator 35027..35824 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828934 YP_424030.1 CDS MCAP_0032 NC_007633.1 35825 36829 D identified by similarity to SP:P55800; match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol-1-phosphate 5-dehydrogenase 35825..36829 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828604 YP_424031.1 CDS MCAP_0033 NC_007633.1 36866 38458 R lipoprotein LppA complement(36866..38458) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828430 YP_424032.1 CDS MCAP_0034 NC_007633.1 38483 40042 R LppA family lipoprotein complement(38483..40042) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829018 YP_424033.1 CDS metG NC_007633.1 40240 41769 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 40240..41769 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828788 YP_424034.1 CDS MCAP_0037 NC_007633.1 43614 45221 D This is part of a two permease, one ATPase ABC transporter cassette. Both permeases have significant HMM socres for PF02653: Branched-chain amino acid transport system / permease component. The best BLAST BER hits are two genes annotated as sugar transporters. Thus we cannot predict a substrate; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 43614..45221 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828932 YP_424035.1 CDS MCAP_0038 NC_007633.1 45211 47769 D This is part of a two permease, one ATPase ABC transporter cassette. Both permeases have significant HMM socres for PF02653: Branched-chain amino acid transport system / permease. component. The best BLAST BER hits are two genes annotated as sugar transporters. Thus we cannot predict a substrate. This protein has a long COOH domain with no TMHs, and may serve as both permaease and substrante binding domain; identified by match to protein family HMM PF02653; ABC transporter permease 45211..47769 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828692 YP_424036.1 CDS MCAP_0039 NC_007633.1 47772 48749 D This is part of a two permease, one ATPase ABC transporter cassette. Both permeases have significant HMM socres for PF02653: Branched-chain amino acid transport system / permease component. The best BLAST BER hits are two genes annotated as sugar transporters. Thus we cannot predict a substrate; identified by match to protein family HMM PF02653; ABC transporter permease 47772..48749 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828490 YP_424037.1 CDS gyrA NC_007633.1 48817 51204 R identified by similarity to SP:P05653; match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01063; DNA gyrase subunit A complement(48817..51204) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829049 YP_424038.1 CDS gyrB NC_007633.1 51336 53240 R identified by similarity to SP:P05652; match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF01751; match to protein family HMM PF02518; match to protein family HMM TIGR01059; DNA gyrase subunit B complement(51336..53240) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828573 YP_424039.1 CDS MCAP_0042 NC_007633.1 53640 55241 R lipoprotein complement(53640..55241) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828743 YP_424040.1 CDS MCAP_0043 NC_007633.1 55409 56182 R MCAP_0043 has 6 membrane spanning regions; The most N-terminal, signal peptide sequence is autoannotated as having a lipoptrotein motif, but it is atypical of many LPs. The orthologous gene of M. mycoides subsp mycoides SC is annotated as a membrane protein.; hypothetical protein complement(55409..56182) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828438 YP_424041.1 CDS MCAP_0044 NC_007633.1 56166 56888 R MCAP_0044 has 6 membrane spanning regions; hypothetical protein complement(56166..56888) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829004 YP_424042.1 CDS secA NC_007633.1 56998 59832 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA complement(56998..59832) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828563 YP_424043.1 CDS MCAP_0046 NC_007633.1 59912 60487 D identified by match to protein family HMM PF01205; hypothetical protein 59912..60487 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828370 YP_424044.1 CDS MCAP_0047 NC_007633.1 60583 61497 D identified by match to protein family HMM PF01367; match to protein family HMM PF02739; 5'-3' exonuclease 60583..61497 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828306 YP_424045.1 CDS MCAP_0048 NC_007633.1 61692 62708 D Part of an apparent operon containing another adenine specific methlyase and a IIS restriction endonuclease; identified by similarity to SP:P14871; match to protein family HMM PF02086; adenine-specific DNA methylase 61692..62708 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828731 YP_424046.1 CDS dam NC_007633.1 62638 63615 D Part of an apparent operon containing another adenine specific methlyase and a IIS restriction endonuclease; identified by similarity to SP:P00475; match to protein family HMM PF02086; DNA adenine methylase 62638..63615 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828741 YP_424047.1 CDS MCAP_0050 NC_007633.1 63593 65170 D There is high identity to a Helicobacter pylori IIS restriction endonuclease recently characterized. This is in an apparent operon with two likely adenine specific DNA methylases; identified by similarity to GB:BAD00171.1; restriction endonuclease 63593..65170 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829082 YP_424048.1 CDS MCAP_0052 NC_007633.1 66644 67114 D hypothetical protein 66644..67114 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828700 YP_424049.1 CDS MCAP_0053 NC_007633.1 67839 68114 D hypothetical protein 67839..68114 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828793 YP_424050.1 CDS MCAP_0054 NC_007633.1 68104 68670 D identified by match to protein family HMM PF01121; match to protein family HMM TIGR00152; dephospho-CoA kinase 68104..68670 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828906 YP_424051.1 CDS MCAP_0055 NC_007633.1 68672 69481 R identified by similarity to SP:Q06803; match to protein family HMM PF01479; match to protein family HMM PF01728; hemolysin A complement(68672..69481) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828753 YP_424052.1 CDS MCAP_0056 NC_007633.1 69481 69696 R hypothetical protein complement(69481..69696) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828754 YP_424053.1 CDS xseA NC_007633.1 69689 71095 R identified by similarity to SP:P04994; match to protein family HMM PF01336; match to protein family HMM PF02601; match to protein family HMM TIGR00237; exodeoxyribonuclease VII large subunit complement(69689..71095) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828583 YP_424054.1 CDS MCAP_0058 NC_007633.1 71097 71495 R identified by match to protein family HMM PF01029; match to protein family HMM TIGR01951; N utilization substance protein B complement(71097..71495) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828497 YP_424055.1 CDS MCAP_0059 NC_007633.1 71507 72577 R MCAP_0059 is a continuous ORF with high DNA similarity to a region in M. mycoides SC annotated as: [MSC_104 - (intergenic region) - MSC_103]; lipoprotein complement(71507..72577) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828558 YP_424056.1 CDS MCAP_0060 NC_007633.1 72604 73473 R Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV complement(72604..73473) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828463 YP_424057.1 CDS MCAP_0061 NC_007633.1 73466 74218 R Similar non-mycoplasma proteins have 65 amino acids at the NH2 end not present in this protein; identified by similarity to SP:P54575; match to protein family HMM PF01687; riboflavin kinase / FAD synthetase family protein complement(73466..74218) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828332 YP_424058.1 CDS MCAP_0063 NC_007633.1 74775 76349 D In the absence of evidence for cell wall or lipopolysccharide synthesis in mycoplasmas, or capsule synthesis in M. capricolum subsp capricolum Kid, the role category biosynthesis/degradation of surface polysaccharides and lipopolysaccharides is assigned to foster comparison with genes having possible capsule-associated functions in other organisms of the Mycoplasma mycoides phylogenetic cluster; identified by match to protein family HMM PF00535; glycosyl transferase family protein 74775..76349 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828858 YP_424059.1 CDS MCAP_0064 NC_007633.1 76352 77230 D identified by match to protein family HMM PF00483; UTP-glucose-1-phosphate uridylyltransferase 76352..77230 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829137 YP_424060.1 CDS rplK NC_007633.1 77432 77860 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 77432..77860 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828682 YP_424061.1 CDS rplA NC_007633.1 77860 78540 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 77860..78540 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828286 YP_424062.1 CDS rplJ NC_007633.1 78769 79266 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 78769..79266 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828491 YP_424063.1 CDS rplL NC_007633.1 79342 79710 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 79342..79710 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828408 YP_424064.1 CDS MCAP_0069 NC_007633.1 79881 81053 D hypothetical protein 79881..81053 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828584 YP_424065.1 CDS rpoB NC_007633.1 81043 84906 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 81043..84906 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828896 YP_424066.1 CDS rpoC NC_007633.1 84918 88685 D identified by similarity to SP:P37871; match to protein family HMM PF00623; match to protein family HMM PF04983; match to protein family HMM PF04997; match to protein family HMM PF04998; match to protein family HMM PF05000; match to protein family HMM TIGR02386; DNA-directed RNA polymerase subunit beta' 84918..88685 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828804 YP_424067.1 CDS MCAP_0072 NC_007633.1 88775 90964 D lipoprotein 88775..90964 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828281 YP_424068.1 CDS MCAP_0073 NC_007633.1 90971 91276 R identified by match to protein family HMM PF00581; hypothetical protein complement(90971..91276) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828395 YP_424069.1 CDS MCAP_0074 NC_007633.1 91301 91798 D identified by similarity to OMNI:NTL02MM0853; match to protein family HMM PF02502; match to protein family HMM TIGR00689; ribose 5-phosphate isomerase B 91301..91798 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828928 YP_424070.1 CDS glyA NC_007633.1 91782 93023 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 91782..93023 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828829 YP_424071.1 CDS upp NC_007633.1 93125 93748 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 93125..93748 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828866 YP_424072.1 CDS MCAP_0077 NC_007633.1 93889 94287 D MCAP_0464 has 4 membrane spanning regions; hypothetical protein 93889..94287 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828786 YP_424073.1 CDS atpB NC_007633.1 94287 95147 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 94287..95147 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828763 YP_424074.1 CDS atpE NC_007633.1 95186 95491 D identified by similarity to SP:O08310; match to protein family HMM PF00137; match to protein family HMM TIGR01260; ATP synthase F0 subunit C 95186..95491 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828566 YP_424075.1 CDS atpF NC_007633.1 95519 96064 D identified by similarity to SP:P37814; match to protein family HMM PF00430; match to protein family HMM TIGR01144; ATP synthase F0 subunit B 95519..96064 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828361 YP_424076.1 CDS atpH NC_007633.1 96066 96611 D produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 96066..96611 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828898 YP_424077.1 CDS atpA1 NC_007633.1 96623 98200 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 96623..98200 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828697 YP_424078.1 CDS atpG NC_007633.1 98202 99044 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 98202..99044 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828996 YP_424079.1 CDS atpD1 NC_007633.1 99053 100483 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 99053..100483 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828383 YP_424080.1 CDS atpC NC_007633.1 100483 100782 D identified by similarity to PIR:S29042; match to protein family HMM PF02823; ATP synthase F1 subunit epsilon 100483..100782 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828324 YP_424081.1 CDS MCAP_0086 NC_007633.1 100840 102051 R MCAP_0086 has 5 membrane spanning regions; hypothetical protein complement(100840..102051) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828874 YP_424082.1 CDS mgtA NC_007633.1 102390 105218 D identified by similarity to SP:P39168; match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01524; magnesium-translocating P-type ATPase 102390..105218 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828492 YP_424083.1 CDS MCAP_0088 NC_007633.1 105679 105813 R MCAP_0088 has 1 membrane spanning region, N-terminal.; hypothetical protein complement(105679..105813) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828462 YP_424084.1 CDS arcA NC_007633.1 105998 107209 D identified by similarity to SP:P16962; match to protein family HMM PF02274; arginine deiminase 105998..107209 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828503 YP_424085.1 CDS arcB NC_007633.1 107227 108222 D identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00658; ornithine carbamoyltransferase, catabolic 107227..108222 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828308 YP_424086.1 CDS MCAP_0091 NC_007633.1 108285 109754 D Part of a likely operon including arginine deaminiase, and ornithine carbamoyltransferase. The match to the PFAM for C4-dicarboxylate anaerobic carrier and the presence of 13 membrane spanning regions support the annotation; identified by match to protein family HMM PF03606; transporter 108285..109754 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829015 YP_424087.1 CDS MCAP_0093 NC_007633.1 111276 112403 R identified by match to protein family HMM PF00144; beta-lactamase complement(111276..112403) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828739 YP_424088.1 CDS ptsG NC_007633.1 112508 114721 R identified by similarity to SP:P20166; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system glucose-specific transporter subunit IIABC complement(112508..114721) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829130 YP_424089.1 CDS MCAP_0095 NC_007633.1 115141 115629 R MCAP_0095 has 1 membrane spanning region, N-terminal.; hypothetical protein complement(115141..115629) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828564 YP_424090.1 CDS smpB NC_007633.1 115629 116075 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(115629..116075) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828806 YP_424091.1 CDS MCAP_0097 NC_007633.1 116085 118199 R identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM TIGR00358; 3'-5' exoribonuclease complement(116085..118199) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828841 YP_424092.1 CDS secG NC_007633.1 118235 118591 R identified by match to protein family HMM TIGR00810; preprotein translocase subunit SecG complement(118235..118591) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829062 YP_424093.1 CDS nrdF NC_007633.1 118773 119792 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 118773..119792 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828363 YP_424094.1 CDS nrdI NC_007633.1 119802 120275 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 119802..120275 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829101 YP_424095.1 CDS nrdE NC_007633.1 120262 122424 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 120262..122424 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828799 YP_424096.1 CDS prs NC_007633.1 122709 123743 D identified by similarity to SP:P14193; match to protein family HMM PF00156; match to protein family HMM TIGR01251; phosphoribosylpyrophosphate synthase 122709..123743 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828790 YP_424097.1 CDS pth NC_007633.1 124048 124608 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 124048..124608 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828326 YP_424098.1 CDS rplI NC_007633.1 124739 125182 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 124739..125182 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828868 YP_424099.1 CDS dnaC NC_007633.1 125184 126512 D identified by match to protein family HMM PF00772; match to protein family HMM PF03796; match to protein family HMM TIGR00665; replicative DNA helicase 125184..126512 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828768 YP_424100.1 CDS MCAP_0108 NC_007633.1 126601 127863 D hypothetical protein 126601..127863 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828576 YP_424101.1 CDS MCAP_0109 NC_007633.1 127990 128916 D MCAP_0109 has 8 membrane spanning regions; hypothetical protein 127990..128916 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829046 YP_424102.1 CDS cysS NC_007633.1 128925 130250 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 128925..130250 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828384 YP_424103.1 CDS MCAP_0111 NC_007633.1 130252 130986 D identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; RNA methyltransferase 130252..130986 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828348 YP_424104.1 CDS rpmG NC_007633.1 131047 131208 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 131047..131208 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828669 YP_424105.1 CDS secE NC_007633.1 131208 131522 D identified by match to protein family HMM TIGR00964; Preprotein translocase subunit SecE 131208..131522 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828904 YP_424106.1 CDS nusG NC_007633.1 131539 132183 D identified by similarity to SP:P36264; match to protein family HMM PF00467; match to protein family HMM PF02357; transcription antitermination protein NusG 131539..132183 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829003 YP_424107.1 CDS MCAP_0115 NC_007633.1 132631 138528 D MCAP_0115 has a lipocalin Prosite signiture. The lipocalins transport small hydrophobic molecules such as steroids, bilins,retinoids, and lipid. They share limited regions of sequence homology and a common tertiary structure architecture. The protein also has a neutral zinc metallopeptidases, zinc-binding region Prosite signature. MCAP_0115 has 1 membrane spanning region, N-terminal.; hypothetical protein 132631..138528 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828893 YP_424108.1 CDS MCAP_0116 NC_007633.1 138537 141491 D MCAP_0116 is part of a 5 gene ABC transporter cassette. It has one transmembrane region; identified by match to protein family HMM PF00496; oligopeptide ABC transporter oligopeptide-binding protein 138537..141491 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828477 YP_424109.1 CDS MCAP_0117 NC_007633.1 141491 142564 D This is part of a 5 gene ABC transporter cassette. It is a good match for B. subtilis oligopeptide transporter permease OppB. Like other genes in this operon it is larger at the NH2 end than orthologs; identified by similarity to SP:P24138; match to protein family HMM PF00528; oligopeptide ABC transporter permease 141491..142564 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829067 YP_424110.1 CDS MCAP_0118 NC_007633.1 142566 143576 D This is part of a 5 gene ABC transporter cassette; identified by similarity to OMNI:SMT1571; match to protein family HMM PF00528; oligopeptide ABC transporter permease 142566..143576 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828784 YP_424111.1 CDS MCAP_0119 NC_007633.1 143655 145028 D This is part of a 5 gene ABC transporter cassette.. This gene is a good match (41% identity) for the B. subtilis OppD protein. The start site makes this gene longer than orthologs in other bacteria. Other start sites look to be worse given that there is a potential RBS at the current start site location but not at other sites farther into the gene; identified by similarity to SP:P24136; match to protein family HMM PF00005; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 143655..145028 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828976 YP_424112.1 CDS MCAP_0120 NC_007633.1 145104 146357 D This is part of a 5 gene ABC transporter cassette; identified by similarity to SP:P24137; match to protein family HMM PF00005; oligopeptide ABC transporter ATP-binding protein 145104..146357 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828445 YP_424113.1 CDS MCAP_0121 NC_007633.1 146389 146817 R MCAP_0121 has 1 membrane spanning region; hypothetical protein complement(146389..146817) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828950 YP_424114.1 CDS MCAP_0122 NC_007633.1 146872 147651 D MCAP_0122 has 6 membrane spanning regions; identified by match to protein family HMM PF02660; match to protein family HMM TIGR00023; membrane protein 146872..147651 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828876 YP_424115.1 CDS MCAP_0123 NC_007633.1 147705 149243 D This protein has two ATPase domains; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 147705..149243 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828889 YP_424116.1 CDS MCAP_0124 NC_007633.1 149275 150072 R identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; TatD family hydrolase complement(149275..150072) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828916 YP_424117.1 CDS ilvA NC_007633.1 150259 151485 D identified by similarity to SP:P11954; match to protein family HMM PF00291; match to protein family HMM TIGR01127; threonine dehydratase 150259..151485 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828312 YP_424118.1 CDS MCAP_0126 NC_007633.1 151701 153290 D MCAP_0126 has 12 membrane spanning regions; hypothetical protein 151701..153290 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828539 YP_424119.1 CDS MCAP_0127 NC_007633.1 153295 154158 D MCAP_0127 has 1 membrane spanning region; hypothetical protein 153295..154158 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828567 YP_424120.2 CDS nagB NC_007633.1 154353 155120 D catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 154353..155120 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828725 YP_424121.1 CDS MCAP_0129 NC_007633.1 155124 156806 D identified by match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system N-acetylglucosamine-specific transporter subunit IIBC 155124..156806 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828330 YP_424122.1 CDS gltX NC_007633.1 156937 158388 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 156937..158388 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828322 YP_424123.1 CDS MCAP_0132 NC_007633.1 159630 160067 D DNA-directed RNA polymerase subunit delta 159630..160067 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829053 YP_424124.1 CDS pyrG NC_007633.1 160160 161758 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 160160..161758 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828399 YP_424125.1 CDS MCAP_0134 NC_007633.1 162260 163033 D MCAP_0134 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0134 has 1 membrane spanning region; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 162260..163033 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828301 YP_424126.1 CDS MCAP_0135 NC_007633.1 163048 164022 D MCAP_0135 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0135 has 2 membrane spanning regions; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 163048..164022 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828678 YP_424127.1 CDS fba NC_007633.1 164174 165067 D identified by similarity to SP:P75089; match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859; fructose-1,6-bisphosphate aldolase 164174..165067 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829112 YP_424128.1 CDS MCAP_0137 NC_007633.1 165285 166778 R MCAP_0137 has 12 membrane spanning regions; hypothetical protein complement(165285..166778) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828454 YP_424129.1 CDS MCAP_0138 NC_007633.1 166983 168434 D MCAP_0138, which has 11 transmembrane regions, is conserved in all the mycoplasmas except Ureaplasma parvum,M. arthritidis, and Phytoplasma asteris. All orthologs have 10-11 transmembrane helices.; hypothetical protein 166983..168434 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828596 YP_424130.1 CDS MCAP_0139 NC_007633.1 168519 169235 D identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 168519..169235 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828391 YP_424131.1 CDS rpmE NC_007633.1 169372 169650 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 169372..169650 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828929 YP_424132.1 CDS MCAP_0141 NC_007633.1 169725 171653 D hypothetical protein 169725..171653 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828942 YP_424133.1 CDS MCAP_0142 NC_007633.1 171663 172613 D identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH phosphoesterase family protein 171663..172613 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828594 YP_424134.1 CDS tdk NC_007633.1 172616 173245 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 172616..173245 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828506 YP_424135.1 CDS prfA NC_007633.1 173248 174339 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 173248..174339 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828470 YP_424136.1 CDS MCAP_0145 NC_007633.1 174332 175144 D identified by match to protein family HMM TIGR00536; HemK family modification methylase 174332..175144 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828317 YP_424137.1 CDS MCAP_0146 NC_007633.1 175190 176662 D MCAP_0146 has 8 membrane spanning regions; hypothetical protein 175190..176662 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828591 YP_424138.1 CDS MCAP_0147 NC_007633.1 176671 177171 D SUA5/yciO/yrdC family signature protein; hypothetical protein 176671..177171 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829141 YP_424139.1 CDS MCAP_0148 NC_007633.1 177239 178192 D hypothetical protein 177239..178192 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828744 YP_424140.1 CDS MCAP_0149 NC_007633.1 178316 179023 D MCAP_0149 has 2 membrane spanning regions; hypothetical protein 178316..179023 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828636 YP_424141.1 CDS MCAP_0150 NC_007633.1 179023 180552 D identified by similarity to SP:O66043; match to protein family HMM PF00614; cardiolipin synthetase 179023..180552 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828464 YP_424142.2 CDS rpsL NC_007633.1 180676 181095 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 180676..181095 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828412 YP_424143.1 CDS rpsG NC_007633.1 181185 181652 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 181185..181652 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828828 YP_424144.1 CDS fusA NC_007633.1 181679 183748 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 181679..183748 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828987 YP_424145.1 CDS tuf NC_007633.1 183880 185067 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 183880..185067 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829066 YP_424146.1 CDS MCAP_0155 NC_007633.1 185190 187031 D although this probably tranports a hexose, one cannot be certain it is glucose; identified by similarity to SP:P19642; match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system transporter subunit IIBC 185190..187031 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828501 YP_424147.1 CDS MCAP_0156 NC_007633.1 187015 189282 D identified by similarity to SP:Q9F234; match to protein family HMM PF01055; isoglycosyl hydrolase family protein 187015..189282 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828327 YP_424148.1 CDS pepA1 NC_007633.1 189469 190824 D MCAP_0195 pepA2 is a paralog of MCAP_0157; identified by match to protein family HMM PF00883; cytosol aminopeptidase 189469..190824 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828696 YP_424149.1 CDS alaS NC_007633.1 192390 195080 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(192390..195080) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828869 YP_424150.1 CDS MCAP_0160 NC_007633.1 195149 195643 R MCAP_0160 has 3 membrane spanning regions; hypothetical protein complement(195149..195643) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828367 YP_424151.1 CDS MCAP_0161 NC_007633.1 195862 197106 D identified by similarity to SP:P24138; match to protein family HMM PF00528; oligopeptide ABC transporter permease 195862..197106 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828476 YP_424152.1 CDS MCAP_0162 NC_007633.1 197122 198132 D identified by similarity to SP:P24139; match to protein family HMM PF00528; oligopeptide ABC transporter permease 197122..198132 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828905 YP_424153.1 CDS MCAP_0163 NC_007633.1 198146 199846 D identified by similarity to SP:P24136; match to protein family HMM PF00005; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 198146..199846 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828380 YP_424154.1 CDS MCAP_0164 NC_007633.1 199848 201725 D identified by similarity to SP:P24137; match to protein family HMM PF00005; oligopeptide ABC transporter ATP-binding protein 199848..201725 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829000 YP_424155.1 CDS MCAP_0165 NC_007633.1 201742 204849 D This is part of a ABC transporter cassette for oligopeptides. It is a hit for the characterized Streptococcus pyogenes OppF; identified by similarity to SP:P35592; match to protein family HMM PF00496; oligopeptide ABC transporter oligopeptide-binding protein 201742..204849 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829139 YP_424156.1 CDS MCAP_0166 NC_007633.1 204948 205049 D A large integrated element (designated Tra island II) is integrated into MCAP_0166; As a consequence of this event MCAP_0166 represents the N-terminal portion of a larger ORF. The C-terminal portion is represented in MCAP_0188. The last 9 amino acids of MCAP_0166 are derived by read through into the element. Nondisrupted orthologs of MCAP_0188/0166 have been sequenced for 3 additional M. capricolum subsp. capricolum isolates. 205021 is first nt of TraI2 element. MCAP_0166 contains 1 membrane spanning region, N-terminal. The C-terminal portion of the disrupted ORF (MCAP_0188) contains 2 membrane spanning regions and encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif.; truncated membrane protein 204948..205049 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828955 YP_424157.1 CDS MCAP_0167 NC_007633.1 205361 206965 D First ORF in integrated element (designated Tra island II). This island spans nucleotides 205021-227425 and encodes ORFs MCAP_0167-MCAP_0187. Weak homology to DnaC helicases; identified by Glimmer2; hypothetical protein 205361..206965 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828331 YP_424158.1 CDS MCAP_0168 NC_007633.1 207895 209073 D MCAP_0168, encoded within Tra island II, has 1 membrane spanning region; hypothetical protein 207895..209073 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828716 YP_424159.1 CDS MCAP_0169 NC_007633.1 209054 209689 D MCAP_0275, MCAP_0314 and MCAP_0169 form a highly paralagous family (>92% amino acid sequence identity)of hypothetical proteins of unknown function. MCAP_0275 and MCAP_0314 are encoded in Tra island I. MCAP_0169 is encoded in Tra island II; hypothetical protein 209054..209689 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828734 YP_424160.1 CDS MCAP_0170 NC_007633.1 209791 210543 D This ORF, resident within Tra island II, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 209791..210543 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829073 YP_424161.1 CDS MCAP_0171 NC_007633.1 210593 211243 D MCAP_0171, encoded within Tra island II, has 4 membrane spanning regions; hypothetical protein 210593..211243 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828941 YP_424162.1 CDS MCAP_0172 NC_007633.1 211364 212194 D lipoprotein 211364..212194 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828288 YP_424163.1 CDS MCAP_0173 NC_007633.1 212404 212691 D This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. The reading frame is open for 87 codons 5' to the Met codon and overlaps upstream MCAP_0172. MCAP_0172 and MCAP_0173 may constitute a single gene with a frameshift mutation; identified by Glimmer2; hypothetical protein 212404..212691 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828293 YP_424164.1 CDS MCAP_0175 NC_007633.1 213766 214179 D MCAP_0175, resident within Tra Island II, exhibits high amino acid sequence identity to Tra Island I encoded MCAP_0295 (88% amino acid identity).; hypothetical protein 213766..214179 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828770 YP_424165.1 CDS MCAP_0176 NC_007633.1 214289 214405 R hypothetical protein complement(214289..214405) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828991 YP_424166.1 CDS MCAP_0177 NC_007633.1 214527 214916 D This ORF, resident within Tra Island II, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM TIGR02167; hypothetical protein 214527..214916 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829090 YP_424167.1 CDS MCAP_0178 NC_007633.1 215059 216234 D MCAP_0178, encoded within Tra Island II, has 6 membrane spanning regions; hypothetical protein 215059..216234 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828630 YP_424168.1 CDS MCAP_0179 NC_007633.1 216319 219186 D MCAP_0179, encoded within Tra Island II, has homology to TraE/TrsE orthologs encoded within mobile DNAs. Contains two membrane spanning regions; membrane bound ATPase 216319..219186 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828507 YP_424169.1 CDS MCAP_0180 NC_007633.1 219507 219827 D hypothetical protein 219507..219827 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828837 YP_424170.1 CDS MCAP_0181 NC_007633.1 219869 220444 D MCAP_0181, encoded by Tra Island II, exhibits weak homology to ICEF ORF11, an ORF of unknown function encoded by an Integrative Conjugal Element of Mycoplasma fermentans. Tra Island I encoded ORFs MCAP_0278 and MCAP_0279 also exhibit similar low homology to ICEF ORF11; identified by Glimmer2; hypothetical protein 219869..220444 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829143 YP_424171.1 CDS MCAP_0182 NC_007633.1 220472 221119 D MCAP_0182, encoded within Tra Island II, is >93% identical to MCAP_0297 encoded within Tra Island I; identified by match to protein family HMM PF02086; adenine-specific DNA methylase 220472..221119 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828422 YP_424172.1 CDS MCAP_0183 NC_007633.1 221144 221575 D MCAP_0183, encoded within Tra Island II, has 90% amino acid sequence identity to MCAP_0298 encoded within Tra Island I.; hypothetical protein 221144..221575 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828530 YP_424173.1 CDS MCAP_0184 NC_007633.1 221642 222379 D Homology in amino-terminus to ParA family of DNA partitioning proteins. Paralog encoded by MCAP_0282 is resident within Tra Island I; identified by Glimmer2; hypothetical protein 221642..222379 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828913 YP_424174.1 CDS MCAP_0185 NC_007633.1 222379 222585 D Hypothetical protein encoded by Tra Island II. Paralogous MCAP_0283(45% amino acid sequence identity) encoded within Tra Island I; identified by Glimmer2; hypothetical protein 222379..222585 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828883 YP_424175.1 CDS MCAP_0186 NC_007633.1 222935 225676 D MCAP_0186, resident in Tra Island II, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0186 has two membrane spanning regions; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 222935..225676 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828737 YP_424176.1 CDS MCAP_0187 NC_007633.1 226062 227186 D Homology to IS3 family transposases. Last gene of Tra Island II. This island spans nucleotides 205021-227425 and encodes ORFs MCAP_0167-MCAP_0187; identified by match to protein family HMM PF00665; IS3 family transposase 226062..227186 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828862 YP_424177.1 CDS MCAP_0189 NC_007633.1 228765 229850 D This looks like an ATP binding protein for a sugar ABC transporter; however there are no other ABC transporter components in the region; identified by similarity to SP:Q00752; match to protein family HMM PF00005; multiple sugar ABC transporter ATP-binding protein 228765..229850 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828309 YP_424178.1 CDS MCAP_0190 NC_007633.1 229949 232246 D identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636; maltose phosphorylase 229949..232246 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828912 YP_424179.1 CDS MCAP_0191 NC_007633.1 232248 233852 D identified by similarity to SP:P39795; match to protein family HMM PF00128; glycosyl hydrolase family protein 232248..233852 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829104 YP_424180.1 CDS MCAP_0192 NC_007633.1 233874 234593 D identified by match to protein family HMM PF00392; GntR family transcriptional regulator 233874..234593 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828778 YP_424181.1 CDS MCAP_0193 NC_007633.1 234626 236419 R identified by match to protein family HMM PF01432; match to protein family HMM TIGR00181; oligoendopeptidase F complement(234626..236419) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828949 YP_424182.1 CDS MCAP_0194 NC_007633.1 236419 237102 R hypothetical protein complement(236419..237102) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828861 YP_424183.1 CDS pepA2 NC_007633.1 237118 238473 R MCAP_0157 pepA1 is a paralog of MCAP_0195; identified by match to protein family HMM PF00883; cytosol aminopeptidase complement(237118..238473) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828294 YP_424184.1 CDS MCAP_0196 NC_007633.1 238589 239884 R This protein has a Prosite motif for an ATP/GTP-binding site A (P-loop).; hypothetical protein complement(238589..239884) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828590 YP_424185.1 CDS MCAP_0197 NC_007633.1 240127 240747 D This protein and the one encoded by the adjacent both have significant hits to the chromate ion transporter (CHR) family HMM(PF02417). Combined the two proteins have the proper size and requisite 10 transmembrane alpha-helical spanners. In B. subtilis and other Gram positives the transporter is comprised to two genes like here. These tranporters are characterized chromate efflux pumps of P. aeruginosa and A. eutrophus; identified by similarity to SP:P17551; match to protein family HMM PF02417; chromate transporter 240127..240747 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829026 YP_424186.1 CDS MCAP_0198 NC_007633.1 240747 241424 D This protein and the one encoded by the adjacent both have significant hits to the chromate ion transporter (CHR) family HMM(PF02417). Combined the two proteins have the proper size and requisite 10 transmembrane alpha-helical spanners. In B. subtilis and other Gram positives the transporter is comprised to two genes like here. These tranporters are characterized chromate efflux pumps of P. aeruginosa and A. eutrophus.; chromate transporter 240747..241424 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828340 YP_424187.1 CDS MCAP_0200 NC_007633.1 242913 246038 R This large protein has 7 transmembrate helices at at the NH2 end plus a signal peptide. Also there is no likely indendent substrate binding protein in the region; identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease and spermidine/putrescine-binding protein complement(242913..246038) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828421 YP_424188.1 CDS MCAP_0201 NC_007633.1 246023 247015 R This and other orthologous mycoplasma spermidine/putrescine ABC transporter permeases have 45 amino acids at the NH2 end not present in otherwise very similar proteins in other bacteria; identified by similarity to SP:P23860; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease complement(246023..247015) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829126 YP_424189.1 CDS MCAP_0202 NC_007633.1 247015 248070 R identified by match to protein family HMM PF00005; spermidine/putrescine ABC transporter ATP-binding protein complement(247015..248070) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828933 YP_424190.1 CDS rplT NC_007633.1 248432 248791 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(248432..248791) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828973 YP_424191.1 CDS rpmI NC_007633.1 248810 249001 R identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 complement(248810..249001) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828280 YP_424192.1 CDS infC NC_007633.1 249027 249572 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(249027..249572) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828450 YP_424193.1 CDS def NC_007633.1 249761 250363 R identified by match to protein family HMM PF01327; match to protein family HMM TIGR00079; polypeptide deformylase complement(249761..250363) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829109 YP_424194.1 CDS MCAP_0207 NC_007633.1 250437 250994 D identified by match to protein family HMM PF03602; methyltransferase 250437..250994 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828730 YP_424195.1 CDS gmk NC_007633.1 250997 251890 D identified by match to protein family HMM PF00625; guanylate kinase 250997..251890 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828787 YP_424196.1 CDS MCAP_0209 NC_007633.1 251853 253139 D Although the TIGRFAM score is above the trusted cutoff, there is no characterised sun protein with >35% identity, The E. coli gene is only 28% identical; identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; rRNA methyltransferase RsmB (sun protein) 251853..253139 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828366 YP_424197.1 CDS typA NC_007633.1 253143 254972 R identified by similarity to SP:Q9EXN7; match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; GTP-binding protein TypA/BipA complement(253143..254972) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828411 YP_424198.1 CDS MCAP_0211 NC_007633.1 255250 256059 D This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein 255250..256059 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828909 YP_424199.1 CDS MCAP_0212 NC_007633.1 256070 256867 D This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein 256070..256867 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828802 YP_424200.1 CDS eno NC_007633.1 256990 258345 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 256990..258345 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828581 YP_424201.1 CDS MCAP_0214 NC_007633.1 258411 259232 D identified by match to protein family HMM PF01569; PAP2 superfamily domain-containing protein 258411..259232 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828997 YP_424202.1 CDS MCAP_0215 NC_007633.1 259234 259665 D identified by match to protein family HMM PF03652; match to protein family HMM TIGR00250; holliday junction resolvase 259234..259665 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828860 YP_424203.1 CDS hpt1 NC_007633.1 259671 260243 D MCAP_0765 (hpt2) is a paralog of MCAP_0216; identified by similarity to SP:Q02522; match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 259671..260243 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828857 YP_424204.1 CDS MCAP_0217 NC_007633.1 260290 261069 R identified by match to protein family HMM PF00230; glycerol uptake facilitator protein complement(260290..261069) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828571 YP_424205.1 CDS glpK NC_007633.1 261105 262622 R identified by similarity to SP:P08859; match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01311; glycerol kinase complement(261105..262622) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828718 YP_424206.1 CDS MCAP_0219 NC_007633.1 262639 263802 R While the annotation of MCAP_0129 is , M. capricolum does have glycerol-3-phosphate dehyrogenase activity; identified by similarity to GP:26454097; match to protein family HMM PF01266; glycerol-3-phosphate dehydrogenase complement(262639..263802) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828473 YP_424207.1 CDS pfkA NC_007633.1 264143 265123 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 264143..265123 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829069 YP_424208.1 CDS pyk NC_007633.1 265192 266628 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 265192..266628 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828599 YP_424209.1 CDS thrS NC_007633.1 266899 268818 D identified by similarity to SP:P18255; match to protein family HMM PF00587; match to protein family HMM PF02824; match to protein family HMM PF03129; match to protein family HMM TIGR00418; threonyl-tRNA synthetase 266899..268818 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828379 YP_424210.1 CDS MCAP_0223 NC_007633.1 269448 270812 D MCAP_0223 is a paralog of MCAP_0858; identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; NADH oxidase 269448..270812 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828429 YP_424211.1 CDS MCAP_0224 NC_007633.1 270824 271828 D identified by similarity to SP:P32099; match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate-protein ligase 270824..271828 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828543 YP_424212.1 CDS pdhA NC_007633.1 271863 272975 D identified by similarity to SP:P21881; match to protein family HMM PF00676; pyruvate dehydrogenase complex, EI component subunit alpha 271863..272975 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828691 YP_424213.1 CDS pdhB NC_007633.1 272975 273964 D identified by similarity to SP:P21882; match to protein family HMM PF02779; match to protein family HMM PF02780; pyruvate dehydrogenase complex, E1 component subunit beta 272975..273964 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828875 YP_424214.1 CDS pdhC NC_007633.1 273993 275309 D identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; branched-chain alpha-keto acid dehydrogenase subunit E2 273993..275309 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828394 YP_424215.1 CDS pdhD NC_007633.1 275328 277217 D identified by similarity to GB:AAA21748.1; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoamide dehydrogenase 275328..277217 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829042 YP_424216.1 CDS pta NC_007633.1 277239 278207 D identified by similarity to SP:P39646; match to protein family HMM PF01515; match to protein family HMM TIGR00651; phosphate acetyltransferase 277239..278207 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828892 YP_424217.1 CDS ackA NC_007633.1 278221 279402 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 278221..279402 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828773 YP_424218.1 CDS MCAP_0231 NC_007633.1 279470 281437 D identified by match to protein family HMM PF01732; lipoprotein 279470..281437 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828347 YP_424219.1 CDS coaD NC_007633.1 281447 281869 D catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-CoA; phosphopantetheine adenylyltransferase 281447..281869 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828952 YP_424220.1 CDS ptsI NC_007633.1 281962 283683 D The M. capricolum phosphoenolpyruvate-protein phosphotransferase (ptsI) was cloned, expressed and characterized in Zhu,P.P., Reizer,J. and Peterkofsky,A. 1994.Unique dicistronic operon (ptsI-crr) in Mycoplasma capricolum encoding enzyme I and the glucose-specific enzyme IIA of the phosphoenolpyruvate:sugar phosphotransferase system: cloning, sequencing, promoter analysis, and protein characterization. Protein Sci. 3 (11), 2115-2128; identified by similarity to SP:P45617; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 281962..283683 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828981 YP_424221.1 CDS crr NC_007633.1 283765 284229 D This M. capricolum protein was characterized in: Zhu,P.P., Reizer,J. and Peterkofsky,A.. 1994.Unique dicistronic operon (ptsI-crr) in Mycoplasma capricolum encoding enzyme I and the glucose-specific enzyme IIA of the phosphoenolpyruvate:sugar phosphotransferase system: cloning, sequencing, promoter analysis, and protein characterization. Protein Sci. 3 (11), 2115-2128 (1994); identified by similarity to SP:P45618; match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system glucose-specific transporter subunit IIA 283765..284229 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828900 YP_424222.1 CDS MCAP_0235 NC_007633.1 284721 285347 D In E. coli dihydroxyacetone kinase is encoded by two proteins. MCAP_0235 corresponds to the C-=terminal part. M. capricolum likely uses dihydroxyacetone kinase under anaerobic conditions along with triosephosphate isomerase to catalyzes the transformation of dihydroxyacetone to glyceraldehyde-3-phosphate. This then feeds into glycolysis; identified by similarity to SP:P76014; match to protein family HMM PF02734; match to protein family HMM TIGR02365; dihydroxyacetone kinase family protein 284721..285347 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829115 YP_424223.1 CDS MCAP_0236 NC_007633.1 285355 285744 D identified by match to protein family HMM PF03610; match to protein family HMM TIGR02364; PTS system mannnose-specific transporter subunit IIA 285355..285744 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829133 YP_424224.1 CDS rpsD NC_007633.1 285801 286427 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(285801..286427) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828736 YP_424225.1 CDS MCAP_0238 NC_007633.1 286682 288469 D MCAP_0238 has 1 membrane spanning region, N-terminal; hypothetical protein 286682..288469 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828512 YP_424226.1 CDS thiI NC_007633.1 288478 289665 D The characterized E. coli ThiI has a COOH terminal rhodanese domain (3-mercaptopyruvate sulfotransferase) not found in the mycpolasma ThiI proteins; identified by similarity to SP:Q8FKB7; match to protein family HMM PF02568; match to protein family HMM PF02926; match to protein family HMM TIGR00342; thiamine biosynthesis protein ThiI 288478..289665 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828407 YP_424227.1 CDS MCAP_0240 NC_007633.1 289797 291767 D MCAP_0240 has 2 membrane spanning regions and a likely C-terminal peptidase domain; identified by match to protein family HMM PF03572; hypothetical protein 289797..291767 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828495 YP_424228.1 CDS MCAP_0241 NC_007633.1 291884 293554 D MCAP_0241 has one membrane spanning region; hypothetical protein 291884..293554 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828990 YP_424229.1 CDS MCAP_0242 NC_007633.1 293564 295852 D This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. Strong coiled-coil prediction in region 1-525 of this ORF. QVRP motifs extend from that region to the C-terminus; identified by match to protein family HMM TIGR02167; lipoprotein 293564..295852 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828761 YP_424230.1 CDS MCAP_0243 NC_007633.1 296087 298150 D MCAP_0243 has 9 transmembrane regions. The Clostridium perfringens PfoR protein was shown to regulate the downstream bperfringolysin O gene. The deduced amino acid sequence of the C. perfringens pfoR possesses several motifs that are characteristic of DNA-binding proteins. When a region coding for a helix-turn-helix, one of the most important motifs of DNA-binding proteins, was deleted within pfoR, stimulation was completely abolished; identified by similarity to PIR:A43577; regulatory protein PfoR 296087..298150 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828487 YP_424231.1 CDS MCAP_0244 NC_007633.1 298176 301091 R identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; cation transporter E1-E2 family ATPase complement(298176..301091) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829055 YP_424232.1 CDS engB NC_007633.1 301100 301690 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(301100..301690) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828378 YP_424233.1 CDS MCAP_0246 NC_007633.1 301684 302244 R MCAP_0246 has 3 membrane spanning regions; hypothetical protein complement(301684..302244) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828927 YP_424234.1 CDS MCAP_0247 NC_007633.1 302246 302824 R MCAP_0247 has 1 membrane spanning region, N-terminal; hypothetical protein complement(302246..302824) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828404 YP_424235.1 CDS MCAP_0248 NC_007633.1 302827 303516 R hypothetical protein complement(302827..303516) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829102 YP_424236.1 CDS MCAP_0249 NC_007633.1 303598 304293 D hypothetical protein 303598..304293 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828439 YP_424237.1 CDS MCAP_0250 NC_007633.1 304294 305016 R identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase complement(304294..305016) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828988 YP_424238.1 CDS greA NC_007633.1 305075 305548 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(305075..305548) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828680 YP_424239.1 CDS uvrC NC_007633.1 305640 307394 R identified by similarity to SP:P14951; match to protein family HMM PF01541; match to protein family HMM PF02151; match to protein family HMM TIGR00194; excinuclease ABC subunit C complement(305640..307394) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828962 YP_424240.1 CDS MCAP_0253 NC_007633.1 307403 308479 R MCAP_0253 has 6 membrane spanning regions; hypothetical protein complement(307403..308479) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828314 YP_424241.1 CDS MCAP_0255 NC_007633.1 310275 312026 R Contains an ATP-binding domain at the N-terminal end of the protein. Possibly part of a superfamily of beta-lactmases; identified by match to protein family HMM PF00753; hypothetical protein complement(310275..312026) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828747 YP_424242.1 CDS MCAP_0256 NC_007633.1 312145 312864 R identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase complement(312145..312864) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829094 YP_424243.1 CDS MCAP_0257 NC_007633.1 312876 313673 R identified by match to protein family HMM PF01513; inorganic polyphosphate/ATP-NAD kinase complement(312876..313673) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828780 YP_424244.1 CDS valS NC_007633.1 313797 316415 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(313797..316415) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828894 YP_424245.1 CDS MCAP_0259 NC_007633.1 316500 317126 R This protein has a thiamin pyrophosphokinase, catalytic domain (EC# 2.7.6.2); identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378; hypothetical protein complement(316500..317126) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828362 YP_424246.1 CDS rpe NC_007633.1 317116 317793 R identified by match to protein family HMM PF00834; ribulose-phosphate 3-epimerase complement(317116..317793) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829002 YP_424247.1 CDS rsgA NC_007633.1 317795 318697 R identified by match to protein family HMM PF03193; match to protein family HMM TIGR00157; ribosome small subunit-dependent GTPase A complement(317795..318697) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828972 YP_424248.1 CDS MCAP_0262 NC_007633.1 318707 319822 R identified by similarity to GB:AAL58474.1; match to protein family HMM PF00069; serine/threonine protein kinase complement(318707..319822) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829134 YP_424249.1 CDS MCAP_0263 NC_007633.1 319822 320085 R hypothetical protein complement(319822..320085) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828824 YP_424250.1 CDS MCAP_0264 NC_007633.1 320054 320581 R The orthologous genes in other organisms are annotated as serine/threonine phosphatase; however no clear case can be made for this gene having that enzymatic activity based on sequence homology to known serine/threonine phosphatases.; hypothetical protein complement(320054..320581) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828792 YP_424251.1 CDS MCAP_0265 NC_007633.1 320611 322023 R MCAP_0265 has 1 membrane spanning region; hypothetical protein complement(320611..322023) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828609 YP_424252.1 CDS MCAP_0266 NC_007633.1 322126 322542 D Thiw protein contains a P-loop and a nucleotide-binding motif GXXGXGKT characteristic of the TIGR00150 proteins; identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 322126..322542 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828623 YP_424253.1 CDS MCAP_0267 NC_007633.1 322544 323107 D This has a ProDom Peptidase M22, glycoprotease signature. This is a member of COG1214 Inactive homologs of metal-dependent proteases, molecular chaperones. Is is conserved in all mycoplasma genomes except Phytoplasma asteris. The gene cannot be disrupted in M. genitalium; identified by match to protein family HMM PF00814; metalloendopeptidase 322544..323107 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828612 YP_424254.1 CDS MCAP_0268 NC_007633.1 323167 324522 R This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM TIGR02167; lipoprotein complement(323167..324522) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828373 YP_424255.1 CDS MCAP_0269 NC_007633.1 324791 326143 R This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM TIGR02167; lipoprotein complement(324791..326143) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828695 YP_424256.1 CDS MCAP_0270 NC_007633.1 326350 331656 R This appears to be an ABC transporter permease or possibly a permease/substrate bindng protein; however there is no ATPase in the vicinity. There are similar genes in other mycoplasmas also without nearby ATPases; identified by match to protein family HMM PF02687; ABC transporter permease complement(326350..331656) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829028 YP_424257.1 CDS MCAP_0271 NC_007633.1 331924 335061 D MCAP_0271 has 1 membrane spanning region, N-terminal.; hypothetical protein 331924..335061 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829024 YP_424258.1 CDS MCAP_0272 NC_007633.1 335085 335603 D lipoprotein 335085..335603 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828621 YP_424259.1 CDS MCAP_0273 NC_007633.1 335689 336228 D lipoprotein 335689..336228 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829059 YP_424260.1 CDS MCAP_0274 NC_007633.1 336621 337358 D First ORF of Tra Island I. Element starts at nucleotide 336353 and encodes MCAP_0274-MCAP_0315. The last nucleotide of the element is 379887; identified by Glimmer2; hypothetical protein 336621..337358 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828349 YP_424261.1 CDS MCAP_0275 NC_007633.1 338352 338984 D MCAP_0275, MCAP_0314 and MCAP_0169 form a highly paralagous family (>92% amino acid sequence identity)of hypothetical proteins of unknown function. MCAP_0275 and MCAP_0314 are encoded in Tra Island I. MCAP_0169 is encoded in Tra Island II; hypothetical protein 338352..338984 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828939 YP_424262.1 CDS MCAP_0276 NC_007633.1 339294 339815 D MCAP_0276, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. The annotated start site is in a repeat motif. In-frame sequence extends nearly 90 amino acid residues 5' from the start, but no alternative start codon occurs in the extension. The extended region also has good homology with orthologous ORFs in M. mycoides SC: MSC_0203 and MSC_0209; identified by match to protein family HMM TIGR02167; hypothetical protein 339294..339815 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829064 YP_424263.1 CDS MCAP_0277 NC_007633.1 339845 340249 D MCAP_0277 is truncated in size compared to the Helicobacter pylori and M. mycoides plasmid homologs. However, homologs from M. capricolum subspecies capripneumoniae strain F38 and Mycoplasma bovine group 7 are also shorter, suggesting that a deletion has not occurred in MCAP_0277 (unpublished findings); identified by similarity to GP:150185; plasmid replication-initiation protein 339845..340249 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828311 YP_424264.1 CDS MCAP_0278 NC_007633.1 340321 340929 D Tra Island I encoded ORF with weak homology to ICEF ORF11, an ORF of unknown function encoded by an Integrative Conjugal Element of Mycoplasma fermentans. Tra Island I encoded MCAP_0279 and Tra Island II encoded MCAP_0181 also exhibit similar low homology to ICEF ORF11.; hypothetical protein 340321..340929 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828279 YP_424265.1 CDS MCAP_0279 NC_007633.1 340973 341833 D Tra Island I encoded ORF with weak homology to ICEF ORF11, an ORF of unknown function encoded by an Integrative Conjugal Element of Mycoplasma fermentans. Tra Island I encoded MCAP_0278 and Tra Island II encoded MCAP_0181 also exhibit similar low homology to ICEF ORF11; identified by Glimmer2; hypothetical protein 340973..341833 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828569 YP_424266.1 CDS MCAP_0280 NC_007633.1 342147 342296 D Tra Island I encoded ORF; identified by Glimmer2; hypothetical protein 342147..342296 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828809 YP_424267.1 CDS MCAP_0281 NC_007633.1 342461 342769 D Tra Island I encoded ORF; identified by similarity to GP:1763709; match to protein family HMM PF00436; single-strand binding protein family 342461..342769 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828814 YP_424268.1 CDS MCAP_0282 NC_007633.1 342820 343560 D Homology to ParA family proteins involved in partitioning of mobile elements. Paralogs are within Tra Island II (MCAP_0184) and Integrative Conjugal Element (ICEC) MCAP_0570; identified by Glimmer2; hypothetical protein 342820..343560 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828884 YP_424269.1 CDS MCAP_0283 NC_007633.1 343562 343777 D Hypothetical protein encoded within Tra Island I. Paralogous MCAP_0185 (45% amino acid identity) encoded within Tra Island II; identified by Glimmer2; hypothetical protein 343562..343777 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828984 YP_424270.1 CDS MCAP_0284 NC_007633.1 343855 344736 D MCAP_0284, resident within Tra Island I, has 5 membrane spanning regions; The C-terminal 94 amino acid residue region exhibits homology to MCAP_0086 and M. mycoides SC ORF MSC_0882.; hypothetical protein 343855..344736 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829088 YP_424271.1 CDS MCAP_0285 NC_007633.1 344834 345322 D Tra Island I encoded ORF; identified by Glimmer2; hypothetical protein 344834..345322 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828823 YP_424272.1 CDS MCAP_0286 NC_007633.1 345374 345943 D Tra Island I encoded ORF; identified by Glimmer2; hypothetical protein 345374..345943 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829084 YP_424273.1 CDS MCAP_0287 NC_007633.1 346021 346839 D This Tra Island I resident ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein 346021..346839 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829099 YP_424274.1 CDS MCAP_0288 NC_007633.1 346886 347458 D This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 346886..347458 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829129 YP_424275.1 CDS MCAP_0289 NC_007633.1 347716 348396 D This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 347716..348396 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828393 YP_424276.1 CDS MCAP_0290 NC_007633.1 348460 348876 D Tra Island I encoded ORF; identified by Glimmer2; hypothetical protein 348460..348876 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828406 YP_424277.1 CDS MCAP_0291 NC_007633.1 348951 349499 D This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 348951..349499 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828455 YP_424278.1 CDS MCAP_0292 NC_007633.1 349555 350307 D This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 349555..350307 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828285 YP_424279.1 CDS MCAP_0293 NC_007633.1 350364 351119 D This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 350364..351119 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828769 YP_424280.1 CDS MCAP_0294 NC_007633.1 351168 351779 D Tra Island I encoded ORF; identified by Glimmer2; hypothetical protein 351168..351779 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828386 YP_424281.1 CDS MCAP_0295 NC_007633.1 351830 352243 D MCAP_0295, resident within Tra Island I, exhibits high amino acid sequence identity to Tra Island II encoded MCAP_0175 (88% amino acid identity).; hypothetical protein 351830..352243 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828701 YP_424282.1 CDS MCAP_0296 NC_007633.1 352322 353125 D This Tra Island I encodede ORF has strong homology to MSC_0201 in M. mycoides SC; hypothetical protein 352322..353125 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829007 YP_424283.1 CDS MCAP_0297 NC_007633.1 353126 353794 D MCAP_0297, resident within Tra Island I, exhibits strong homology to MCAP_0182 encoded within Tra Island II; identified by match to protein family HMM PF02086; adenine-specific DNA methylase 353126..353794 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828750 YP_424284.1 CDS MCAP_0298 NC_007633.1 353798 354178 D MCAP_0298, resident within Tra Island I, has high sequence identity (90% amino acid level) to MCAP_0183, encoded within Tra Island II.; hypothetical protein 353798..354178 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829080 YP_424285.1 CDS MCAP_0299 NC_007633.1 354758 359698 D MCAP_0299, resident within Tra Island I, has 2 membrane spanning regions; MCAP_0299 corresponds to an orthologous region in M. mycoides SC PG1 annotated to encode four contiguous ORFS (MSC_0198, MSC_0197, MSC_0196 and MSC_0195), which may be separated by interspersed frameshifts relative to MCAP_0299.; hypothetical protein 354758..359698 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829103 YP_424286.1 CDS MCAP_0300 NC_007633.1 360401 361894 R Tra Island I resident ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(360401..361894) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828706 YP_424287.1 CDS MCAP_0301 NC_007633.1 362143 364599 R Tra Island I encoded ORF exhibits homology to multiple ORFs annotated as TraE/TrsE family NTPases.; hypothetical protein complement(362143..364599) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828853 YP_424288.1 CDS MCAP_0302 NC_007633.1 364659 365339 R This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(364659..365339) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828375 YP_424289.1 CDS MCAP_0303 NC_007633.1 366143 366730 R MCAP_0303, resident within Tra Island I, contains 2 membrane spanning regions; hypothetical protein complement(366143..366730) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828568 YP_424290.1 CDS MCAP_0304 NC_007633.1 366730 368646 R MCAP_0304 is encoded within Tra Island I. There are two of these genes in M. mycoides SC; however both genes are divided into two parts. The HN2 domain of the M. capricolum gene with the 5 transmembrane helices is one SC ORF and the e3 binding domain is the other. The e3 binding domain is a small domain of the E2 subunit of 2-oxo-acid dehydrogenases that is responsible for the binding of the E3 subunit. Proteins containing the e3 binding domain include the branched-chain -keto acid dehydrogenase complex of bacteria, which catalyses the overall conversion of -keto acids to acyl-CoA and carbon dioxide; identified by match to protein family HMM PF02817; E3 binding domain-containing protein complement(366730..368646) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828471 YP_424291.1 CDS MCAP_0305 NC_007633.1 368903 370393 R MCAP_0305, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0305 has 1 membrane spanning region, N-terminal; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(368903..370393) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828335 YP_424292.1 CDS MCAP_0306 NC_007633.1 370524 370844 R MCAP_0306, encoded within Tra Island I, has 2 membrane spanning regions; hypothetical protein complement(370524..370844) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828674 YP_424293.1 CDS MCAP_0307 NC_007633.1 371320 372405 R MCAP_0307, encoded within Tra Island I, has 2 membrane spanning regions; There is a DnaJ domain; identified by match to protein family HMM PF00226; hypothetical protein complement(371320..372405) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828579 YP_424294.1 CDS MCAP_0308 NC_007633.1 372470 373015 R This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(372470..373015) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829075 YP_424295.1 CDS MCAP_0309 NC_007633.1 373077 374006 R This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(373077..374006) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828440 YP_424296.1 CDS MCAP_0310 NC_007633.1 374061 374963 R This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(374061..374963) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828699 YP_424297.1 CDS MCAP_0311 NC_007633.1 375026 375997 R This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(375026..375997) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828995 YP_424298.1 CDS MCAP_0312 NC_007633.1 376060 377175 R This ORF, resident within Tra Island I, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein complement(376060..377175) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828947 YP_424299.1 CDS hupB NC_007633.1 377232 377510 R MCAP_0313 is one of three M. capricolum ORFs with homology to multiple HU-like DNA binding proteins. MCAP_0575 is identical to the single HU-like protein of M. mycoides SC (MSC_0410) and is most likely therefore the chromosomal equivalent of HU. MCAP_0313 is a Tra Island I encoded paralog. MCAP_0813 also exhibits homology to HU proteins; identified by similarity to SP:P02346; match to protein family HMM PF00216; DNA-binding protein, HU complement(377232..377510) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828535 YP_424300.1 CDS MCAP_0314 NC_007633.1 377579 378211 R MCAP_0275, MCAP_0314 and MCAP_0169 form a highly paralagous family (>92% amino acid sequence identity)of hypothetical proteins of unknown function. MCAP_0275 and MCAP_0314 are encoded in Tra Island I. MCAP_0169 is encoded in Tra Island II; hypothetical protein complement(377579..378211) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828638 YP_424301.1 CDS MCAP_0315 NC_007633.1 378592 379707 D Terminal ORF of Tra island I. Element starts at nucleotide 336353 and encodes MCAP_0274-MCAP_0315. The last nucleotide of the element is 379887; identified by match to protein family HMM PF00665; IS3 family transposase 378592..379707 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828854 YP_424302.1 CDS MCAP_0317 NC_007633.1 380492 381184 D hypothetical protein 380492..381184 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828416 YP_424303.2 CDS proS NC_007633.1 381165 382589 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 381165..382589 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828890 YP_424304.1 CDS MCAP_0319 NC_007633.1 382602 383222 D identified by match to protein family HMM PF00075; ribonuclease H1 382602..383222 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829009 YP_424305.1 CDS MCAP_0320 NC_007633.1 383224 384123 D hypothetical protein 383224..384123 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828805 YP_424306.1 CDS lepA NC_007633.1 384137 385939 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 384137..385939 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828815 YP_424307.1 CDS MCAP_0322 NC_007633.1 385973 386776 D hypothetical protein 385973..386776 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829011 YP_424308.1 CDS aspS NC_007633.1 386797 388524 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(386797..388524) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829065 YP_424309.1 CDS hisS NC_007633.1 388533 389777 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(388533..389777) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828446 YP_424310.1 CDS rbfA NC_007633.1 389949 390302 D identified by similarity to SP:P09170; match to protein family HMM PF02033; match to protein family HMM TIGR00082; ribosome-binding factor A 389949..390302 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828472 YP_424311.1 CDS MCAP_0326 NC_007633.1 390352 391230 D This gene has good similariy to the characterized 286 amino acid E. coli TruB protein for the first 2215 amino acids, after that there is no similarity. This also true for other mycoplasma tRNA pseudouridine synthases; identified by similarity to SP:P32732; match to protein family HMM PF01509; match to protein family HMM TIGR00431; tRNA pseudouridine synthase B 390352..391230 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829091 YP_424312.1 CDS MCAP_0327 NC_007633.1 391217 391771 D Similar non-mycoplasma proteins have and additional 120 amino acids at the COOH end; identified by similarity to SP:P54575; match to protein family HMM PF06574; riboflavin kinase domain-containing protein 391217..391771 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828958 YP_424313.1 CDS MCAP_0328 NC_007633.1 391784 393832 R MCAP_0328 has 1 membrane spanning region; identified by match to protein family HMM PF03572; hypothetical protein complement(391784..393832) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828720 YP_424314.1 CDS MCAP_0329 NC_007633.1 393844 395682 R identified by match to protein family HMM PF03572; lipoprotein complement(393844..395682) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829061 YP_424315.1 CDS rpsO NC_007633.1 395895 396161 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 395895..396161 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828414 YP_424316.1 CDS MCAP_0332 NC_007633.1 396385 397035 D There are 4 membrane spanning regions in MCAP_0332.; hypothetical protein 396385..397035 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829052 YP_424317.1 CDS infB NC_007633.1 397049 398911 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(397049..398911) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829005 YP_424318.1 CDS MCAP_0334 NC_007633.1 398931 399230 R identified by match to protein family HMM PF01248; ribosomal protein L7A family protein complement(398931..399230) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828776 YP_424319.1 CDS MCAP_0335 NC_007633.1 399217 399504 R identified by match to protein family HMM PF04296; hypothetical protein complement(399217..399504) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828759 YP_424320.1 CDS nusA NC_007633.1 399479 401155 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(399479..401155) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828290 YP_424321.1 CDS MCAP_0337 NC_007633.1 401164 401658 R hypothetical protein complement(401164..401658) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828299 YP_424322.1 CDS MCAP_0338 NC_007633.1 401771 402394 R identified by match to protein family HMM PF00881; nitroreductase family protein complement(401771..402394) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828880 YP_424323.1 CDS polC NC_007633.1 402434 406873 R identified by similarity to SP:P13267; match to protein family HMM PF00929; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00573; match to protein family HMM TIGR01405; DNA polymerase III subunit alpha complement(402434..406873) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828732 YP_424324.1 CDS cdsA NC_007633.1 406882 407910 R identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase complement(406882..407910) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828481 YP_424325.1 CDS MCAP_0341 NC_007633.1 408108 409184 R identified by match to protein family HMM PF00557; Xaa-Pro peptidase complement(408108..409184) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829034 YP_424326.1 CDS trpS NC_007633.1 409342 410352 D identified by match to protein family HMM PF00579; match to protein family HMM TIGR00233; tryptophanyl-tRNA synthetase 409342..410352 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828377 YP_424327.1 CDS MCAP_0343 NC_007633.1 410382 411272 R MCAP_0343 has 1 membrane spanning region; hypothetical protein complement(410382..411272) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828964 YP_424328.1 CDS MCAP_0344 NC_007633.1 411606 412175 D identified by match to protein family HMM PF02661; Fic family protein 411606..412175 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828710 YP_424329.1 CDS MCAP_0345 NC_007633.1 412795 415050 D MCAP_0345 has 1 membrane spanning region, N-terminal; identified by match to protein family HMM TIGR02184; hypothetical protein 412795..415050 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828345 YP_424330.1 CDS MCAP_0346 NC_007633.1 415071 417659 D lipoprotein 415071..417659 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828740 YP_424331.1 CDS MCAP_0347 NC_007633.1 417869 420121 D MCAP_0347 has 1 membrane spanning region, N-terminal; identified by match to protein family HMM TIGR02184; hypothetical protein 417869..420121 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828967 YP_424332.1 CDS MCAP_0348 NC_007633.1 420139 422718 D lipoprotein 420139..422718 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829050 YP_424333.1 CDS MCAP_0349 NC_007633.1 422903 425152 D MCAP_0349 has 1 membrane spanning region, N-terminal; identified by match to protein family HMM TIGR02184; hypothetical protein 422903..425152 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829117 YP_424334.1 CDS MCAP_0350 NC_007633.1 425172 427751 D lipoprotein 425172..427751 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829072 YP_424335.1 CDS MCAP_0351 NC_007633.1 428011 430263 D MCAP_0351 has one membrane spanning region, N-terminal; identified by match to protein family HMM TIGR02184; hypothetical protein 428011..430263 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828459 YP_424336.1 CDS MCAP_0352 NC_007633.1 430287 432854 D lipoprotein 430287..432854 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828353 YP_424337.1 CDS MCAP_0353 NC_007633.1 432889 434352 D MCAP_0353 has 12 membrane spanning regions; hypothetical protein 432889..434352 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828551 YP_424338.1 CDS MCAP_0354 NC_007633.1 434327 434821 D hypothetical protein 434327..434821 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828673 YP_424339.1 CDS MCAP_0355 NC_007633.1 434823 435734 D hypothetical protein 434823..435734 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829071 YP_424340.1 CDS MCAP_0356 NC_007633.1 435734 436177 D hypothetical protein 435734..436177 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828442 YP_424341.1 CDS MCAP_0357 NC_007633.1 436179 438446 D There are 3 membrane spanning regions in MCAP_0357.; hypothetical protein 436179..438446 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828865 YP_424342.1 CDS atpA2 NC_007633.1 438451 439998 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 438451..439998 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828320 YP_424343.1 CDS atpD2 NC_007633.1 439998 441377 D produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 439998..441377 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828797 YP_424344.1 CDS MCAP_0360 NC_007633.1 441432 443936 R hypothetical protein complement(441432..443936) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828484 YP_424345.1 CDS MCAP_0361 NC_007633.1 444199 446745 R hypothetical protein complement(444199..446745) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829029 YP_424346.1 CDS MCAP_0362 NC_007633.1 446899 449406 R hypothetical protein complement(446899..449406) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828844 YP_424347.1 CDS MCAP_0363 NC_007633.1 449586 450185 D This proteins is 31% identical to the characterized E. coli RdgB, which is a pyrophosphatases active against non-standard purines NTPs. E. coli RdgB appears to act by intercepting non-canonical deoxyribonucleotide triphosphates from replication precursor pools; identified by similarity to SP:P94558; match to protein family HMM PF01725; match to protein family HMM TIGR00042; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 449586..450185 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828319 YP_424348.1 CDS MCAP_0364 NC_007633.1 450199 450744 D identified by match to protein family HMM PF00588; RNA methyltransferase 450199..450744 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828526 YP_424349.1 CDS MCAP_0365 NC_007633.1 450744 451610 D identified by match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 450744..451610 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829136 YP_424350.1 CDS MCAP_0366 NC_007633.1 451775 453916 D identified by match to protein family HMM PF00004; match to protein family HMM PF07724; ATP-dependent Clp protease, ATP-binding subunit ClpB 451775..453916 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828675 YP_424351.1 CDS hrcA NC_007633.1 453921 454943 D identified by match to protein family HMM PF01628; match to protein family HMM TIGR00331; heat-inducible transcription repressor HrcA 453921..454943 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828723 YP_424352.1 CDS grpE NC_007633.1 454927 455547 D Start site prediction for grpE is uncertain. No ribosome binding site is predicted. We elect to make the largest ORF possible and have the gene start similar to the one choosen for the ortholog in Mycoplasma mycoides SC; identified by match to protein family HMM PF01025; co-chaperone GrpE 454927..455547 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828825 YP_424353.1 CDS dnaK NC_007633.1 455607 457382 D HSP70; heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 455607..457382 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828296 YP_424354.1 CDS dnaJ NC_007633.1 457447 458565 D HSP40; chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 457447..458565 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828575 YP_424355.1 CDS rpsB NC_007633.1 458769 459644 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 458769..459644 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828690 YP_424356.1 CDS tsf NC_007633.1 459656 460543 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 459656..460543 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829125 YP_424357.1 CDS MCAP_0373 NC_007633.1 460546 461151 D There are 3 membrane spanning regions in MCAP_0373.; hypothetical protein 460546..461151 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828822 YP_424358.1 CDS pyrH NC_007633.1 461283 461996 D identified by match to protein family HMM PF00696; match to protein family HMM TIGR02075; uridylate kinase 461283..461996 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828536 YP_424359.1 CDS frr NC_007633.1 462007 462555 D identified by match to protein family HMM PF01765; match to protein family HMM TIGR00496; ribosome recycling factor 462007..462555 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828505 YP_424360.1 CDS argS NC_007633.1 462557 464221 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 462557..464221 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828392 YP_424361.1 CDS MCAP_0381 NC_007633.1 469387 473832 D MCAP_0381 has 8 membrane spanning regions; This protein characteristics of an ABC transporter permease; however it is not near any ATPase; identified by match to protein family HMM PF02687; hypothetical protein 469387..473832 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829127 YP_424362.1 CDS MCAP_0382 NC_007633.1 473844 474452 D hypothetical protein 473844..474452 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829132 YP_424363.1 CDS pheS NC_007633.1 474483 475535 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 474483..475535 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829087 YP_424364.1 CDS pheT NC_007633.1 475544 477928 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 475544..477928 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828897 YP_424365.1 CDS MCAP_0385 NC_007633.1 477928 478443 D hypothetical protein 477928..478443 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828616 YP_424366.1 CDS rpmF NC_007633.1 478458 478637 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 478458..478637 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828545 YP_424367.1 CDS MCAP_0387 NC_007633.1 478742 479140 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 478742..479140 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828873 YP_424368.1 CDS mraW NC_007633.1 479149 480078 D This protein has 41% identity to the characterized E. coli MraW; identified by similarity to OMNI:SA1192; match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 479149..480078 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829025 YP_424369.1 CDS MCAP_0389 NC_007633.1 480087 481244 D hypothetical protein 480087..481244 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828757 YP_424370.1 CDS ftsZ NC_007633.1 481359 482498 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 481359..482498 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828608 YP_424371.1 CDS MCAP_0391 NC_007633.1 482511 482954 D hypothetical protein 482511..482954 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828686 YP_424372.1 CDS MCAP_0392 NC_007633.1 482987 483976 D hypothetical protein 482987..483976 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828426 YP_424373.1 CDS ileS NC_007633.1 484559 487285 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 484559..487285 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828544 YP_424374.1 CDS lspA NC_007633.1 487294 487902 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 487294..487902 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828943 YP_424375.1 CDS MCAP_0395 NC_007633.1 487883 488851 D This protein is 33% identical to the characterized E. coli pseudouridine synthase (PMID: 9814761); identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase A 487883..488851 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828419 YP_424376.1 CDS MCAP_0396 NC_007633.1 488835 490145 D MCAP_0396 has 7 membrane spanning regions; hypothetical protein 488835..490145 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828919 YP_424377.1 CDS MCAP_0397 NC_007633.1 490172 490633 D identified by similarity to SP:P16006; match to protein family HMM PF00383; deoxycytidylate deaminase 490172..490633 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828970 YP_424378.1 CDS MCAP_0398 NC_007633.1 490673 491827 D MCAP_0398 has two membrane spanning regions; hypothetical protein 490673..491827 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828724 YP_424379.1 CDS MCAP_0399 NC_007633.1 491908 493293 D MCAP_0399 has 2 membrane spanning regions; hypothetical protein 491908..493293 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828945 YP_424380.1 CDS MCAP_0400 NC_007633.1 493313 493645 D identified by match to protein family HMM PF01648; match to protein family HMM TIGR00556; holo-(acyl-carrier-protein) synthase 493313..493645 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828458 YP_424381.1 CDS MCAP_0401 NC_007633.1 493687 494838 D MCAP_0401 has 2 membrane spanning regions; hypothetical protein 493687..494838 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828907 YP_424382.1 CDS MCAP_0402 NC_007633.1 494973 495926 D identified by match to protein family HMM PF01553; 1-acyl-sn-glycerol-3-phosphate acyltransferase 494973..495926 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828848 YP_424383.1 CDS MCAP_0403 NC_007633.1 495977 496594 D hypothetical protein 495977..496594 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828282 YP_424384.1 CDS MCAP_0409 NC_007633.1 497250 498314 R lipoprotein complement(497250..498314) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828953 YP_424385.1 CDS MCAP_0410 NC_007633.1 498691 499581 D identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein 498691..499581 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828694 YP_424386.1 CDS MCAP_0411 NC_007633.1 499603 500004 D hypothetical protein 499603..500004 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828504 YP_424387.1 CDS rplU NC_007633.1 500149 500451 D identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 500149..500451 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828722 YP_424388.1 CDS MCAP_0413 NC_007633.1 500454 500768 D identified by match to protein family HMM PF04327; hypothetical protein 500454..500768 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828337 YP_424389.1 CDS rpmA NC_007633.1 500770 501051 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 500770..501051 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829016 YP_424390.1 CDS nanA NC_007633.1 501245 502132 D catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 501245..502132 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828601 YP_424391.1 CDS MCAP_0416 NC_007633.1 502136 503848 D This protein has the 13 TMH characteristic of bacterial sodium:solute symporters. It is not clear what solute is transported in addition to sodium; identified by match to protein family HMM PF00474; sodium/solute symporter family protein 502136..503848 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829030 YP_424392.1 CDS MCAP_0417 NC_007633.1 503857 504306 D identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 503857..504306 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828447 YP_424393.1 CDS MCAP_0418 NC_007633.1 504299 505174 D identified by match to protein family HMM PF00480; ROK family protein 504299..505174 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828689 YP_424394.1 CDS MCAP_0419 NC_007633.1 505254 505934 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 505254..505934 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828617 YP_424395.1 CDS MCAP_0420 NC_007633.1 506088 507437 D This tart site is uncertain. There is no clear ribosome binding site. The start could be at the L or V just upstream; identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887; dipeptidase 506088..507437 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828960 YP_424396.1 CDS MCAP_0421 NC_007633.1 507518 507952 D There are 4 membrane spanning regions in MCAP_0421.; hypothetical protein 507518..507952 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828728 YP_424397.1 CDS udk NC_007633.1 507977 508600 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 507977..508600 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828360 YP_424398.1 CDS MCAP_0423 NC_007633.1 508728 509954 D Similar genes are annotated as DNA polymerase IV (EC 2.7.7.7) or damage inducible repair proteins (dinB); identified by match to protein family HMM PF00817; ImpB/MucB/SamB family protein 508728..509954 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828493 YP_424399.1 CDS MCAP_0424 NC_007633.1 509967 511070 R identified by match to protein family HMM PF01926; hypothetical protein complement(509967..511070) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828483 YP_424400.1 CDS MCAP_0425 NC_007633.1 511079 511999 R hypothetical protein complement(511079..511999) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828771 YP_424401.1 CDS MCAP_0426 NC_007633.1 512075 512890 D hypothetical protein 512075..512890 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828808 YP_424402.1 CDS MCAP_0427 NC_007633.1 512935 514296 R Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(512935..514296) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828448 YP_424403.1 CDS ruvA NC_007633.1 515351 515911 R identified by similarity to SP:P75243; Holliday junction DNA helicase ruvA complement(515351..515911) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828485 YP_424404.2 CDS rpsU NC_007633.1 516022 516186 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(516022..516186) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829047 YP_424405.1 CDS MCAP_0431 NC_007633.1 516454 517083 D lipoprotein 516454..517083 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829081 YP_424406.1 CDS MCAP_0432 NC_007633.1 517320 518039 D lipoprotein 517320..518039 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828777 YP_424407.1 CDS MCAP_0433 NC_007633.1 518278 518916 D lipoprotein 518278..518916 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828846 YP_424408.1 CDS MCAP_0434 NC_007633.1 518964 520697 R hypothetical protein complement(518964..520697) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828300 YP_424409.1 CDS MCAP_0435 NC_007633.1 520850 522502 D There are 2 membrane spanning regions in MCAP_0435.; hypothetical protein 520850..522502 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828339 YP_424410.1 CDS MCAP_0436 NC_007633.1 522507 523106 D There are 4 membrane spanning regions in MCAP_0436.; hypothetical protein 522507..523106 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828546 YP_424411.1 CDS MCAP_0437 NC_007633.1 523118 523927 R MCAP_0437 has 6 membrane spanning regions; hypothetical protein complement(523118..523927) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828840 YP_424412.1 CDS nagA NC_007633.1 524021 525178 D identified by similarity to SP:O34450; match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 524021..525178 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828297 YP_424413.1 CDS ldh NC_007633.1 525231 526184 D identified by similarity to SP:P13714; match to protein family HMM PF00056; match to protein family HMM PF02866; match to protein family HMM TIGR01771; lactate dehydrogenase 525231..526184 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829124 YP_424414.1 CDS MCAP_0440 NC_007633.1 526250 526912 R MCAP_0440 has 6 membrane spanning regions; identified by match to protein family HMM PF01061; hypothetical protein complement(526250..526912) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828796 YP_424415.1 CDS MCAP_0441 NC_007633.1 527269 527469 R MCAP_0441 is encoded within a truncated form of the Integrative Conjugal Element of M. capricolum (ICEC). A complete element encodes the paralog MCAP_0562 (100% identity); identified by Glimmer2; hypothetical protein complement(527269..527469) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828482 YP_424416.1 CDS MCAP_0442 NC_007633.1 527481 528965 R MCAP_0442 and MCAP_0561 are paralogs (88% amino acid identity). MCAP_0561 is encoded by Integrative Conjugal Element of M. capricolum (ICEC). MCAP_0442 may be encoded within a remnant of ICEC.; lipoprotein complement(527481..528965) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828749 YP_424417.1 CDS MCAP_0443 NC_007633.1 529220 529492 D hypothetical protein 529220..529492 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828549 YP_424418.1 CDS MCAP_0444 NC_007633.1 529607 530716 D MCAP_0444 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. There are 2 membrane spanning regions in MCAP_0444; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 529607..530716 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829114 YP_424419.1 CDS MCAP_0445 NC_007633.1 530742 531539 R MCAP_0446 is a paralog of this triacylglycerol lipase gene; identified by match to protein family HMM PF00561; triacylglycerol lipase complement(530742..531539) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828628 YP_424420.1 CDS MCAP_0446 NC_007633.1 531553 532341 R There are multiple orthologs of this protein in Mycoplasma mycoides SC. This protien is frame shifted relative to one but not others. In M. capricolum the next gene, MCAP_0445, is a paralog of this likely triacylglycerol lipase gene; identified by match to protein family HMM PF00561; triacylglycerol lipase complement(531553..532341) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828413 YP_424421.1 CDS MCAP_0447 NC_007633.1 532528 532872 D glycine cleavage system H protein 532528..532872 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828871 YP_424422.1 CDS MCAP_0448 NC_007633.1 532879 533730 D hypothetical protein 532879..533730 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828830 YP_424423.1 CDS MCAP_0449 NC_007633.1 533708 534745 D identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate-protein ligase 533708..534745 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828918 YP_424424.1 CDS MCAP_0450 NC_007633.1 534745 535923 D identified by similarity to OMNI:SA0392; match to protein family HMM PF00724; NADH:flavin oxidoreductase/NADH oxidase family protein 534745..535923 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828478 YP_424425.1 CDS MCAP_0451 NC_007633.1 536187 538070 R identified by match to protein family HMM PF03202; lipoprotein LppB complement(536187..538070) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828727 YP_424426.1 CDS gtsC NC_007633.1 538184 538987 R The M. mycoides glycerol ABC transporter that is nearly identical to this M. capricolum ABC transporter cassette was biochemically characterized: Vilei EM, Frey J. 2001. Genetic and biochemical characterization of glycerol uptake in mycoplasma mycoides subsp. mycoides SC: its impact on H(2)O(2) production and virulence. Clinical Diagn Lab Immunol. 8(1):85-92; identified by similarity to GP:11934746; match to protein family HMM PF00528; glycerol ABC transporter permease complement(538184..538987) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829113 YP_424427.1 CDS gtsB NC_007633.1 538965 539969 R The M. mycoides glycerol ABC transporter that is nearly identical to this M. capricolum ABC transporter cassette was biochemically characterized: Vilei EM, Frey J. 2001. Genetic and biochemical characterization of glycerol uptake in mycoplasma mycoides subsp. mycoides SC: its impact on H(2)O(2) production and virulence. Clin Diagn Lab Immunol. 8(1):85-92; identified by similarity to GP:11934745; glycerol ABC transporter permease complement(538965..539969) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828965 YP_424428.1 CDS gtsA NC_007633.1 539962 541173 R The M. mycoides glycerol ABC transporter that is nearly identical to this M. capricolum ABC transporter cassette was biochemically characterized: Vilei EM, Frey J. 2001. Genetic and biochemical characterization of glycerol uptake in mycoplasma mycoides subsp. mycoides SC: its impact on H(2)O(2) production and virulence. Clinical Diagn Lab Immunol. 8(1):85-92; identified by similarity to GP:11934744; match to protein family HMM PF00005; glycerol ABC transporter ATP-binding protein complement(539962..541173) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828510 YP_424429.1 CDS MCAP_0455 NC_007633.1 541179 543374 R recombinase D complement(541179..543374) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829036 YP_424430.1 CDS parC NC_007633.1 543485 546184 R identified by similarity to SP:P72525; match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; DNA topoisomerase IV subunit A complement(543485..546184) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828405 YP_424431.1 CDS parE NC_007633.1 546186 548117 R identified by similarity to SP:Q59192; match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF01751; match to protein family HMM PF02518; match to protein family HMM TIGR01058; DNA topoisomerase IV subunit B complement(546186..548117) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829140 YP_424432.1 CDS MCAP_0458 NC_007633.1 548347 549924 D identified by similarity to SP:P00550; match to protein family HMM PF02302; PTS system mannitol-specific transporter subunit IIBC 548347..549924 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828735 YP_424433.1 CDS MCAP_0459 NC_007633.1 549927 550367 D identified by similarity to SP:P27547; match to protein family HMM PF00359; PTS system mannitol-specific transporter subunit IIA 549927..550367 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829001 YP_424434.1 CDS MCAP_0460 NC_007633.1 550367 551266 D similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase 550367..551266 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829144 YP_424435.1 CDS MCAP_0461 NC_007633.1 551321 552736 R identified by match to protein family HMM PF00171; aldehyde dehydrogenase (NAD) family protein complement(551321..552736) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828843 YP_424436.1 CDS MCAP_0462 NC_007633.1 552903 553670 R identified by similarity to OMNI:NTL01LP1288; match to protein family HMM PF00588; match to protein family HMM PF08032; RNA methyltransferase complement(552903..553670) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828600 YP_424437.1 CDS MCAP_0463 NC_007633.1 553687 554190 R The gene is conserved in the sprioplasma/mycoides group and the hominus group of the mycoplasmas but not in any of the pneumoniae group species.; hypothetical protein complement(553687..554190) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828511 YP_424438.1 CDS MCAP_0464 NC_007633.1 554231 554677 R MCAP_0464 has 3 membrane spanning regions; hypothetical protein complement(554231..554677) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828836 YP_424439.1 CDS pgi NC_007633.1 554703 555986 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(554703..555986) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828818 YP_424440.1 CDS pepO NC_007633.1 556207 558102 R identified by similarity to GB:AAD40473.1; match to protein family HMM PF01431; match to protein family HMM PF05649; endopeptidase O complement(556207..558102) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828548 YP_424441.1 CDS MCAP_0467 NC_007633.1 558116 558685 R identified by match to protein family HMM PF01812; 5-formyltetrahydrofolate cyclo-ligase complement(558116..558685) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828831 YP_424442.1 CDS MCAP_0468 NC_007633.1 558678 559115 R hypothetical protein complement(558678..559115) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828329 YP_424443.1 CDS MCAP_0469 NC_007633.1 559119 560357 R identified by match to protein family HMM PF00266; class V aminotransferase complement(559119..560357) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828961 YP_424444.1 CDS MCAP_0470 NC_007633.1 560551 563544 D lipoprotein 560551..563544 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828812 YP_424445.1 CDS MCAP_0471 NC_007633.1 563566 565737 D lipoprotein 563566..565737 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828738 YP_424446.1 CDS MCAP_0472 NC_007633.1 565740 566135 D identified by similarity to SP:O07513; match to protein family HMM PF01230; HIT family protein 565740..566135 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828992 YP_424447.1 CDS MCAP_0473 NC_007633.1 566171 567151 R identified by match to protein family HMM PF01336; match to protein family HMM PF01966; hypothetical protein complement(566171..567151) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829097 YP_424448.1 CDS ung NC_007633.1 567220 567876 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(567220..567876) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828733 YP_424449.1 CDS pmi NC_007633.1 567869 568798 R identified by similarity to SP:P39841; match to protein family HMM PF01238; phosphomannose isomerase type I complement(567869..568798) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828313 YP_424450.1 CDS gid NC_007633.1 568919 570235 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(568919..570235) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828914 YP_424451.1 CDS MCAP_0477 NC_007633.1 570228 570911 R identified by similarity to SP:P46719; match to protein family HMM PF03932; copper homeostasis protein CutC complement(570228..570911) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828586 YP_424452.1 CDS metK NC_007633.1 570902 572065 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(570902..572065) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828502 YP_424453.1 CDS MCAP_0479 NC_007633.1 572276 573049 R identified by match to protein family HMM PF00149; match to protein family HMM TIGR00282; hypothetical protein complement(572276..573049) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828417 YP_424454.1 CDS p13 NC_007633.1 573037 573378 R The p13 protein is encoded by the same operon as a protein homologous to the 54 kDa subunit of SRP, suggesting a functional relationship between the p13 protein and the SRP pathway. The helix-turn-helix motif, suggests the p13 proteins have a regulatory function; identified by similarity to SP:O05290; match to protein family HMM PF04297; DNA-binding protein complement(573037..573378) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828532 YP_424455.1 CDS ftsY NC_007633.1 573362 574636 R identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY complement(573362..574636) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828606 YP_424456.1 CDS MCAP_0482 NC_007633.1 574705 575376 R identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU complement(574705..575376) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828401 YP_424457.1 CDS pstB NC_007633.1 575385 576194 R Part of a 3 transporter gene operon; identified by similarity to SP:P46341; match to protein family HMM PF00005; match to protein family HMM TIGR00972; phosphate ABC transporter ATP-binding protein complement(575385..576194) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828595 YP_424458.1 CDS MCAP_0484 NC_007633.1 576187 578277 R This gene has 30% identity to the characterized E. coli PstA. Part of a 3 transporter gene operon; identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; match to protein family HMM TIGR02138; phosphate ABC transporter permease complement(576187..578277) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828289 YP_424459.1 CDS MCAP_0485 NC_007633.1 578281 579492 R The start site of this protein makes it 25-30 amino acids longer than ortholgous genes. There are no other viable start sites that look better. Part of a 3 transporter gene operon.; phosphate ABC transporter substrate-binding protein complement(578281..579492) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828303 YP_424460.1 CDS MCAP_0486 NC_007633.1 579583 580017 R hypothetical protein complement(579583..580017) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828531 YP_424461.1 CDS rpmB NC_007633.1 580246 580443 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(580246..580443) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828513 YP_424462.1 CDS MCAP_0489 NC_007633.1 580603 580932 D hypothetical protein 580603..580932 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828977 YP_424463.1 CDS MCAP_0490 NC_007633.1 580962 582605 D This protein contains the predicted phosphatase domain of the dihydroxyacetone kinase family; identified by match to protein family HMM PF02734; dihydroxyacetone kinase 2 domain-containing protein 580962..582605 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828316 YP_424464.1 CDS plsX NC_007633.1 582637 583641 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 582637..583641 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828888 YP_424465.1 CDS MCAP_0492 NC_007633.1 583631 584329 D identified by similarity to SP:P51833; match to protein family HMM PF00035; match to protein family HMM PF00636; match to protein family HMM TIGR02191; ribonuclease III 583631..584329 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829010 YP_424466.1 CDS MCAP_0493 NC_007633.1 584513 584908 D Among the mycoplasmas this has similar genes in Ureaplasma parvum and M. mycoides. It is in COG3600 (uncharacterized phage associated proteins); identified by Glimmer2; hypothetical protein 584513..584908 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829070 YP_424467.1 CDS MCAP_0494 NC_007633.1 584911 585297 D hypothetical protein 584911..585297 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828357 YP_424468.1 CDS MCAP_0495 NC_007633.1 585624 588590 D identified by match to protein family HMM PF02463; match to protein family HMM PF02483; match to protein family HMM PF06470; match to protein family HMM TIGR00650; match to protein family HMM TIGR02168; structural maintenance of chromosomes (SMC) superfamily protein 585624..588590 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828382 YP_424469.1 CDS MCAP_0496 NC_007633.1 588629 590893 R identified by similarity to SP:O34098; match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; RelA/SpoT family protein complement(588629..590893) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828372 YP_424470.1 CDS apt NC_007633.1 590953 591465 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(590953..591465) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829135 YP_424471.1 CDS MCAP_0498 NC_007633.1 591477 595691 R MCAP_0498 has 12 membrane spanning regions; hypothetical protein complement(591477..595691) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829116 YP_424472.1 CDS MCAP_0499 NC_007633.1 595793 597304 R MCAP_0499 has 6 membrane spanning regions; identified by match to protein family HMM PF02588; hypothetical protein complement(595793..597304) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829032 YP_424473.1 CDS MCAP_0500 NC_007633.1 597343 598704 R identified by similarity to OMNI:SA1615; match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box helicase complement(597343..598704) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828427 YP_424474.1 CDS MCAP_0501 NC_007633.1 598713 599489 R There is significant homology to an uncharacterized family of proteins. One member of this family NIF3 (NGG1p interacting factor 3) interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex the exact function of this interaction is unknown; identified by match to protein family HMM PF01784; hypothetical protein complement(598713..599489) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828850 YP_424475.1 CDS MCAP_0502 NC_007633.1 599476 600153 R identified by match to protein family HMM PF04816; hypothetical protein complement(599476..600153) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828374 YP_424476.1 CDS rpoD NC_007633.1 600156 601673 R identified by similarity to SP:Q59753; match to protein family HMM PF04539; match to protein family HMM PF04542; RNA polymerase sigma factor RpoD complement(600156..601673) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829106 YP_424477.1 CDS dnaG NC_007633.1 601676 603490 R identified by similarity to SP:P05096; match to protein family HMM PF01751; match to protein family HMM PF01807; match to protein family HMM TIGR01391; DNA primase complement(601676..603490) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828350 YP_424478.1 CDS glyS NC_007633.1 603527 604897 R Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase complement(603527..604897) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829100 YP_424479.1 CDS MCAP_0506 NC_007633.1 604961 605710 R identified by similarity to SP:P42095; match to protein family HMM PF02565; match to protein family HMM TIGR00613; DNA repair protein RecO complement(604961..605710) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828460 YP_424480.1 CDS era NC_007633.1 605710 606615 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(605710..606615) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828766 YP_424481.1 CDS MCAP_0508 NC_007633.1 606618 607112 R identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; hypothetical protein complement(606618..607112) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828782 YP_424482.1 CDS MCAP_0509 NC_007633.1 607118 609007 R identified by match to protein family HMM PF03412; peptidase C39 family protein complement(607118..609007) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828702 YP_424483.1 CDS MCAP_0510 NC_007633.1 609000 609548 R identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; DJ-1 family protein complement(609000..609548) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829085 YP_424484.1 CDS MCAP_0511 NC_007633.1 609596 614857 R MCAP_0511 has 8 membrane spanning regions; MCAP_0511 may be a transporter permease; identified by match to protein family HMM PF02687; hypothetical protein complement(609596..614857) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828456 YP_424485.1 CDS MCAP_0513 NC_007633.1 617508 619751 D lipoprotein 617508..619751 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828767 YP_424486.1 CDS MCAP_0514 NC_007633.1 619809 622079 D lipoprotein 619809..622079 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828704 YP_424487.1 CDS MCAP_0515 NC_007633.1 622111 623349 R AAA ATPases are often associated with chaparonins. This gene is adjacent to the ATP-dependent protease La and trigger factor genes; identified by match to protein family HMM PF00004; recombination factor protein RarA complement(622111..623349) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829128 YP_424488.1 CDS lon NC_007633.1 623462 625801 R identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM TIGR00763; ATP-dependent protease La complement(623462..625801) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828715 YP_424489.1 CDS tig NC_007633.1 625920 627206 R identified by match to protein family HMM PF00254; match to protein family HMM PF05697; match to protein family HMM PF05698; match to protein family HMM TIGR00115; trigger factor complement(625920..627206) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828864 YP_424490.1 CDS MCAP_0518 NC_007633.1 627223 627525 R hypothetical protein complement(627223..627525) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828409 YP_424491.1 CDS efp NC_007633.1 627543 628097 R identified by match to protein family HMM PF01132; match to protein family HMM TIGR00038; translation elongation factor P complement(627543..628097) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828603 YP_424492.1 CDS fmt NC_007633.1 628187 629140 R identified by similarity to SP:P23882; match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR00460; methionyl-tRNA formyltransferase complement(628187..629140) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828998 YP_424493.1 CDS MCAP_0521 NC_007633.1 629130 631274 R hypothetical protein complement(629130..631274) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828688 YP_424494.1 CDS MCAP_0522 NC_007633.1 631351 631968 R MCAP_0522 has 1 membrane spanning region, N-terminal.; hypothetical protein complement(631351..631968) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828356 YP_424495.1 CDS mnmA NC_007633.1 632010 633137 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(632010..633137) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829039 YP_424496.1 CDS MCAP_0524 NC_007633.1 633233 634117 R lipoprotein complement(633233..634117) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828627 YP_424497.1 CDS MCAP_0525 NC_007633.1 634769 635542 R lipoprotein complement(634769..635542) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828625 YP_424498.1 CDS MCAP_0526 NC_007633.1 635564 636367 R lipoprotein complement(635564..636367) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828810 YP_424499.1 CDS MCAP_0527 NC_007633.1 636581 637225 R hypothetical protein complement(636581..637225) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828488 YP_424500.1 CDS MCAP_0528 NC_007633.1 637250 637885 R identified by similarity to SP:O32028; match to protein family HMM PF01048; match to protein family HMM TIGR01704; MTA/SAH nucleosidase complement(637250..637885) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829022 YP_424501.1 CDS nadD NC_007633.1 637908 639011 R catalyzes the reversible adenylation of nicotinate mononucleotide to nicotinic acid adenine dinucleotide; nicotinate-nucleotide adenylyltransferase complement(637908..639011) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829138 YP_424502.1 CDS MCAP_0530 NC_007633.1 639029 639274 R MCAP_0530 has 1 membrane spanning region; hypothetical protein complement(639029..639274) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828403 YP_424503.1 CDS MCAP_0531 NC_007633.1 639292 640053 R identified by similarity to SP:P08164; match to protein family HMM PF02540; match to protein family HMM TIGR00552; NH3-dependent NAD+ synthetase complement(639292..640053) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828755 YP_424504.1 CDS obgE NC_007633.1 640031 641332 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(640031..641332) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828287 YP_424505.1 CDS MCAP_0533 NC_007633.1 641403 641711 R hypothetical protein complement(641403..641711) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828527 YP_424506.1 CDS MCAP_0534 NC_007633.1 641701 642453 R hypothetical protein complement(641701..642453) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828441 YP_424507.1 CDS MCAP_0536 NC_007633.1 642641 644245 R There are very similar proteins in M mycoides (93% amino acid identity) and Mesoplasma florum (32% identit).; hypothetical protein complement(642641..644245) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828719 YP_424508.1 CDS MCAP_0537 NC_007633.1 644285 646138 R The next gene upstream is also an ABC transporter ATP-binding protein/permease. No substrate can be predicted for either element of the cassette; identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease complement(644285..646138) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828817 YP_424509.1 CDS MCAP_0538 NC_007633.1 646156 648027 R The next gene downstream is also an ABC transporter ATP-binding protein/permease. No substrate can be predicted for either element of the cassette; identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease complement(646156..648027) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828677 YP_424510.1 CDS MCAP_0539 NC_007633.1 648243 648548 R identified by match to protein family HMM PF00436; single-strand binding protein family complement(648243..648548) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828499 YP_424511.1 CDS MCAP_0540 NC_007633.1 648710 649948 D MCAP_0540 has 11 transmembrane regions; identified by similarity to SP:P31064; match to protein family HMM PF04143; YeeE/YedE family protein 648710..649948 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828397 YP_424512.1 CDS MCAP_0541 NC_007633.1 649951 651747 D identified by match to protein family HMM PF00581; match to protein family HMM PF02852; match to protein family HMM PF07992; hypothetical protein 649951..651747 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828956 YP_424513.1 CDS MCAP_0542 NC_007633.1 651769 652392 R identified by match to protein family HMM PF01351; ribonuclease HII complement(651769..652392) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828937 YP_424514.1 CDS MCAP_0543 NC_007633.1 652386 653336 R identified by match to protein family HMM PF01926; match to protein family HMM TIGR00650; GTPase family protein complement(652386..653336) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828480 YP_424515.1 CDS rplS NC_007633.1 653429 653821 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(653429..653821) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828343 YP_424516.1 CDS trmD NC_007633.1 653823 654545 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(653823..654545) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828550 YP_424517.1 CDS MCAP_0546 NC_007633.1 654547 655041 R identified by match to protein family HMM TIGR02273; 16S rRNA processing protein RimM complement(654547..655041) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828540 YP_424518.1 CDS rpsP NC_007633.1 655059 655385 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(655059..655385) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828402 YP_424519.1 CDS MCAP_0548 NC_007633.1 655474 655941 R identified by match to protein family HMM PF02590; hypothetical protein complement(655474..655941) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828390 YP_424520.1 CDS ffh NC_007633.1 655947 657290 R identified by similarity to SP:P37105; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein complement(655947..657290) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828729 YP_424521.1 CDS MCAP_0550 NC_007633.1 657320 658849 R protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase complement(657320..658849) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828845 YP_424522.1 CDS recA NC_007633.1 659001 659987 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(659001..659987) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828554 YP_424523.1 CDS MCAP_0552 NC_007633.1 660079 660627 R identified by similarity to SP:P46323; match to protein family HMM PF02464; match to protein family HMM TIGR00199; similar to competence/damage-inducible protein CinA; hypothetical protein complement(660079..660627) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828433 YP_424524.1 CDS MCAP_0554 NC_007633.1 661194 662042 D MCAP_0554 is the first ORF of an Integrative Conjugal Element (ICE) of M. capricolum strain Kid (designated ICEC); Exhibits modest similarity to first ORF of the related element ICEF of Mycoplasma fermentans. MCAP_0554 has 1 membrane spanning region; ICEC is located between nucleotides 661011 and 685387 and encodes ORFs MCAP_0554-MCAP_0571.; hypothetical protein 661194..662042 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828632 YP_424525.1 CDS MCAP_0556 NC_007633.1 663622 664455 D MCAP_0556 is encoded within ICEC element; identified by similarity to GP:21538805; C-5 cytosine-specific DNA methylase 663622..664455 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828371 YP_424526.1 CDS MCAP_0557 NC_007633.1 664567 665148 D MCAP_0557, resident within ICEC element, encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_055 has 1 membrane spanning region; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 664567..665148 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829014 YP_424527.1 CDS MCAP_0558 NC_007633.1 665588 665737 D MCAP_0558 is encoded within ICEC element; identified by Glimmer2; hypothetical protein 665588..665737 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828891 YP_424528.1 CDS MCAP_0559 NC_007633.1 666111 668111 D MCAP_0559 is encoded within ICEC element and exhibits homology to multiple members of the TraG/TraD family of proteins, associated with conjugal plasmids or elements. MACP0559 has 2 membrane spanning regions; identified by match to protein family HMM PF02534; TraG/TraD family membrane protein 666111..668111 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828762 YP_424529.1 CDS MCAP_0560 NC_007633.1 668143 669558 D MCAP_0560, encoded within ICEC, exhibits homology to LtrC-like proteins encoded by plasmids and mobile DNAs.; hypothetical protein 668143..669558 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828582 YP_424530.1 CDS MCAP_0561 NC_007633.1 669691 671172 D MCAP_0561 is encoded within Integrative Conjugal Element of M. capricolum (ICEC). MCAP_0561 and MCAP_0442 are paralogs (88% amino acid identity). MCAP_0422 occurs at a second genomic locus, that probably represents a truncated remnant of ICEC; lipoprotein 669691..671172 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828794 YP_424531.1 CDS MCAP_0562 NC_007633.1 671184 671384 D MCAP_0562 is resident on the Integrative Conjugal Element of M. capricolum (ICEC). A truncated form of this element encodes the paralog MCAP_0441 (100% identity); identified by Glimmer2; hypothetical protein 671184..671384 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828709 YP_424532.1 CDS MCAP_0563 NC_007633.1 671489 671815 D MCAP_0563, resident within ICEC, has 2 membrane spanning regions; hypothetical protein 671489..671815 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828772 YP_424533.1 CDS MCAP_0564 NC_007633.1 671819 673462 D MCAP_0564 has 8 membrane spanning regions; MCAP_0564 is encoded within the Integtaive Conjugal Element of M. capricolum (ICEC). Weak homology to ICEF ORF16 in Mycoplasma fermentans.; hypothetical protein 671819..673462 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828428 YP_424534.1 CDS MCAP_0565 NC_007633.1 673465 676302 D MCAP_0565 is encoded within ICEC and is a NTPase which exhibits homology to multiple TraE/TrsE proteins encoded with conjugative plasmids and elements. MCAP_0565 has 2 membrane spanning regions; hypothetical protein 673465..676302 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828922 YP_424535.1 CDS MCAP_0566 NC_007633.1 676321 676944 D MCAP_0566 is encoded by the Integrative Conjugal Element of M. capricolum (ICEC) and exhibits modest homology to ORF18 encoded by ICEF of M. fermentans; identified by Glimmer2; hypothetical protein 676321..676944 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828859 YP_424536.1 CDS MCAP_0567 NC_007633.1 676937 680959 D MCAP_0567 is encoded within Integrative Conjugal Element of M. capricolum (ICEC) and exhibits homology to ORF19 of ICEF of M. fermentans. MCAP_0567 has one membrane spanning region (C-terminal), and a possible signal peptide.; hypothetical protein 676937..680959 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828284 YP_424537.1 CDS MCAP_0568 NC_007633.1 681011 681991 D Hypothetical protein encoded within Integrative Conjugal Element of M. capricolum (ICEC). The sequence of the small stable RNA mcs4a starts 10nt upstream of MCAP_0568 start codon and extends 110 nt into the MCAP_0568 coding sequence; identified by Glimmer2; hypothetical protein 681011..681991 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828587 YP_424538.1 CDS MCAP_0569 NC_007633.1 682175 682540 D Hypothetical ORF encoded within Integrative Conjugal Element of M. capricolum (ICEC); identified by Glimmer2; hypothetical protein 682175..682540 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828342 YP_424539.1 CDS MCAP_0570 NC_007633.1 682755 683672 D This protein has a CobQ/CobB/MinD/ParA nucleotide binding domain, which is characteristic of a family of various cobyrinic acid a,c-diamide synthases. ParA family proteins are involved in partitioning of mobile elements. Three ParA family members are present in M. capricolum Kid. MCAP_0570 is encoded within ICEC, MCAP_0184 within Tra Island II and MCAP_0282 by Tra Island I; identified by match to protein family HMM PF01656; hypothetical protein 682755..683672 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828944 YP_424540.1 CDS MCAP_0571 NC_007633.1 683782 685014 D MCAP_0571 is the last ORF of an Integrative Conjugal Element (ICE) of M. capricolum strain Kid (designated ICEC); Exhibits modest similarity to ORF22 of the related element ICEF of Mycoplasma fermentans. ICEC is located between nucleotides 661011 and 685387 and encodes ORFs MCAP_0554-MCAP_0571; identified by Glimmer2; hypothetical protein 683782..685014 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828679 YP_424541.1 CDS MCAP_0572 NC_007633.1 685488 685865 R The M. mycoides ortholog is longer at the NH2 end.; hypothetical protein complement(685488..685865) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828886 YP_424542.1 CDS MCAP_0573 NC_007633.1 685929 686438 D identified by similarity to SP:P39792; match to protein family HMM PF03838; recombination protein U 685929..686438 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828605 YP_424543.1 CDS MCAP_0574 NC_007633.1 686410 686946 R hypothetical protein complement(686410..686946) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828820 YP_424544.1 CDS hupA NC_007633.1 687004 687276 R MCAP_0575 is one of three M. capricolum ORFs with homology to multiple HU-like DNA binding proteins. MCAP_0575 is identical to the single HU-like protein of M. mycoides SC (MSC_0410) and is most likely therefore the chromosomal equivalent of HU. MCAP_0313 is a Tra Island I encoded paralog. MCAP_0813 also exhibits homology to HU-like proteins; identified by similarity to SP:P08821; match to protein family HMM PF00216; DNA-binding protein HU 1 complement(687004..687276) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828634 YP_424545.1 CDS gpsA NC_007633.1 687308 688306 R identified by similarity to SP:P46919; match to protein family HMM PF01210; match to protein family HMM PF07479; glycerol-3-phosphate dehydrogenase (NAD(P)+) complement(687308..688306) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829083 YP_424546.1 CDS engA NC_007633.1 688308 689615 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(688308..689615) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828938 YP_424547.1 CDS cmk NC_007633.1 689615 690283 R identified by similarity to SP:P38493; match to protein family HMM PF02224; match to protein family HMM TIGR00017; cytidylate kinase complement(689615..690283) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828631 YP_424548.1 CDS MCAP_0579 NC_007633.1 690292 690987 R MCAP_0579 has 1 membrane spanning region; hypothetical protein complement(690292..690987) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828800 YP_424549.1 CDS MCAP_0580 NC_007633.1 691056 691943 R MCAP_0580 has 5 membrane spanning regions; hypothetical protein complement(691056..691943) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828423 YP_424550.1 CDS ppa NC_007633.1 692084 692644 D identified by similarity to SP:P19514; match to protein family HMM PF00719; inorganic pyrophosphatase 692084..692644 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829020 YP_424551.1 CDS MCAP_0582 NC_007633.1 692752 693453 R hypothetical protein complement(692752..693453) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828899 YP_424552.1 CDS MCAP_0583 NC_007633.1 693511 695775 R MCAP_0583 encodes tandem 9-residue repeats near the predicted C-terminus. The same tandem repeat occurs at the C-terminus of MCAP_0585. These repeats are not encoded by the M. mycoides SC ortholog MSC_0402). The tandem repeat aligns with an 8-residue repeat of S. aureus protein A, but only if gapped, and the alignment is imperfect. Unlike some other repeat-containing lipoprotein ORFs, MCAP_0585 shows no evidence of a flanking 5' repetitive nt tract that might confer variable gene expression.; lipoprotein complement(693511..695775) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828760 YP_424553.1 CDS MCAP_0584 NC_007633.1 695820 695942 R MCAP_0584 encodes the signal peptide of a prolipoprotein and a very short sequence of a mature lipoprotein. No apparent frameshift or point mutation explains the short product that is predicted by this ORF.; lipoprotein complement(695820..695942) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829118 YP_424554.1 CDS MCAP_0585 NC_007633.1 696234 696569 R MCAP_0585 encodes tandem 9-residue repeats near the predicted C-terminus. The same tandem repeat occurs at the C-terminus of MCAP_0583. These repeats are not encoded by the M. mycoides SC ortholog MSC_0402). The tandem repeat aligns with an 8-residue repeat of S. aureus protein A, but only if gapped, and the alignment is imperfect. Unlike some other repeat-containing lipoprotein ORFs, MCAP_0585 shows no evidence of a flanking 5' repetitive nt tract that might confer variable gene expression.; lipoprotein complement(696234..696569) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828508 YP_424555.1 CDS MCAP_0586 NC_007633.1 696604 698397 R This is adjacent ot a ABC transporter ATP-binding protein whose substrate is unknown. The similar protein in Mesplasma florum is 59% identical.In M. mycoides SC, the similar protein is encoded by two ORFs.; ABC transporter permease complement(696604..698397) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829057 YP_424556.1 CDS MCAP_0587 NC_007633.1 698444 700279 R The adjacent gene is a possible membrane permease. It has multiple transmembrane regions. There is no hint of what this tranporter might transport; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(698444..700279) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828467 YP_424557.1 CDS MCAP_0589 NC_007633.1 701486 702133 R identified by similarity to GB:CAE77029.1; match to protein family HMM PF00834; ribulose-phosphate 3-epimerase complement(701486..702133) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829044 YP_424558.1 CDS MCAP_0590 NC_007633.1 702133 703941 R identified by match to protein family HMM PF02302; match to protein family HMM PF04215; PTS system ascorbate-specific transporter subunits IICB complement(702133..703941) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828931 YP_424559.1 CDS MCAP_0591 NC_007633.1 703953 704402 R identified by match to protein family HMM PF00359; PTS system transporter subunit IIA complement(703953..704402) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828833 YP_424560.1 CDS MCAP_0592 NC_007633.1 704691 704795 R hypothetical protein complement(704691..704795) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829098 YP_424561.1 CDS MCAP_0593 NC_007633.1 704901 705830 R Expressed translation product is identified in Triton X114 phase of detergent fractionated organisms, by peptide mass mapping using mass spectrometry. This is consistent with a lipoprotein encoding an otherwise hydrophilic sequence. Tandem repeat sequence occurs in the ORF. Tandem nucleotide repeats of TA occur 5' of the ORF in a promoter region; this tract is possibly subject to dinucleotide indels governing phase variable expression of the gene.; lipoprotein VmcD complement(704901..705830) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828465 YP_424562.1 CDS MCAP_0594 NC_007633.1 706228 706662 R Expressed translation product is identified in Triton X114 phase of detergent fractionated organisms, by peptide mass mapping using mass spectrometry. This is consistent with a lipoprotein encoding an otherwise hydrophilic sequence. Tandem repeat sequence occurs in the ORF. Tandem nucleotide repeats of TA occur 5' of the ORF in a promoter region; this tract is possibly subject to dinucleotide indels governing phase variable expression of the gene.; lipoprotein VmcC complement(706228..706662) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828509 YP_424563.1 CDS MCAP_0595 NC_007633.1 707728 708435 R Expression of translation product is demonstrated by specific antibody to a synthetic peptide encoded by the ORF. Product partitions in Triton X-114 phase of detergent fractionated organisms, consistent with a cell-associated lipoprotein encoding an otherwise hydrophilic sequence. Product is identified on surface of organism by colony immunostaining. Product is also defined by peptide mass mapping using mass spectrometry. Tandem repeat sequence occurs in the ORF. Tandem nucleotide repeats of TA occur 5' of the ORF in a promoter region; this tract is possibly subject to dinucleotide indels governing phase variable expression of the gene.; lipoprotein VmcB complement(707728..708435) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829027 YP_424564.1 CDS MCAP_0596 NC_007633.1 709888 711366 R Expression of the translation product is demonstrated by specific antibody to a synthetic peptide encoded by the ORF. Product partitions in Triton X-114 phase of detergent fractionated organisms, consistent with a cell-associated lipoprotein encoding an otherwise hydrophilic sequence. Product is also defined by peptide mass mapping using mass spectrometry. Tandem repeat sequence occurs in the ORF. Tandem nucleotide repeats of TA occur 5' of the ORF in a promoter region; this tract is possibly subject to dinucleotide indels governing phase variable expression of the gene. The vmcA gene is located in the same genomic position relative to upstream conserved adjacent housekeeping genes as the vmm gene in M. mycoides SC; lipoprotein VmcA complement(709888..711366) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828385 YP_424565.1 CDS MCAP_0597 NC_007633.1 711633 712460 R MCAP_0597 has 3 membrane spanning regions; hypothetical protein complement(711633..712460) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828936 YP_424566.1 CDS MCAP_0598 NC_007633.1 712560 713273 R identified by match to protein family HMM PF01709; hypothetical protein complement(712560..713273) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829086 YP_424567.1 CDS MCAP_0599 NC_007633.1 713285 713902 R identified by similarity to SP:Q59484; match to protein family HMM PF01712; nucleoside kinase complement(713285..713902) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829092 YP_424568.1 CDS MCAP_0600 NC_007633.1 713913 714671 R identified by similarity to SP:P35159; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B complement(713913..714671) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828451 YP_424569.1 CDS scpB NC_007633.1 714745 715374 R This gene is adjacent to the scpA gene; identified by similarity to SP:P35155; match to protein family HMM PF04079; match to protein family HMM TIGR00281; chromosomal segregation and condensation protein B complement(714745..715374) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828336 YP_424570.1 CDS scpA NC_007633.1 715358 716194 R This gene is adjacent to the scpB gene; identified by similarity to SP:P35154; match to protein family HMM PF02616; chromosomal segregation and condensation protein A complement(715358..716194) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829043 YP_424571.1 CDS MCAP_0603 NC_007633.1 716204 716965 R MCAP_0603 has 1 membrane spanning region; hypothetical protein complement(716204..716965) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828712 YP_424572.1 CDS MCAP_0604 NC_007633.1 716977 718476 R MCAP_0604 has 13 membrane spanning regions; hypothetical protein complement(716977..718476) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828795 YP_424573.1 CDS MCAP_0605 NC_007633.1 718785 719183 R lipoprotein complement(718785..719183) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828774 YP_424574.1 CDS MCAP_0606 NC_007633.1 719333 720127 R identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase complement(719333..720127) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828856 YP_424575.1 CDS MCAP_0607 NC_007633.1 720139 722595 R lipoprotein complement(720139..722595) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828498 YP_424576.1 CDS MCAP_0608 NC_007633.1 722695 724239 R hypothetical protein complement(722695..724239) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828713 YP_424577.1 CDS MCAP_0609 NC_007633.1 724303 724548 R ORF00812 has one transmembrane region. ORF00812 a member of a family of bacterial proteins of unknown function. There is good identity with membrane proteins in many mycoplasmas; identified by match to protein family HMM PF03672; hypothetical protein complement(724303..724548) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828982 YP_424578.1 CDS tkt NC_007633.1 724564 726534 R identified by similarity to SP:P45694; match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232; transketolase complement(724564..726534) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828882 YP_424579.1 CDS MCAP_0611 NC_007633.1 726575 726736 R identified by similarity to GB:CAE77008.1; hypothetical protein complement(726575..726736) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828803 YP_424580.1 CDS MCAP_0612 NC_007633.1 726871 727611 R MCAP_0612 has 6 membrane spanning regions; hypothetical protein complement(726871..727611) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828613 YP_424581.1 CDS MCAP_0613 NC_007633.1 727710 728981 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(727710..728981) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828924 YP_424582.1 CDS MCAP_0614 NC_007633.1 729282 730358 D MCAP_0614 is similar to the RmuC protein family. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures. MCAP_0614 has 1 membrane spanning region, N-terminal.; hypothetical protein 729282..730358 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828387 YP_424583.1 CDS MCAP_0615 NC_007633.1 730500 730739 R The amino terminal 42 amino acids of this protein are 86% identical to the M. mycoides SC hypothetical protein MSC_0648. The carboxyl terminal 42 amino acids are 86% identical to M. mycoides SC hypothetical protein MSC_0638.; hypothetical protein complement(730500..730739) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828940 YP_424584.1 CDS MCAP_0616 NC_007633.1 730932 731777 R identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; fructose/tagatose bisphosphate aldolase, class II complement(730932..731777) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828556 YP_424585.1 CDS MCAP_0617 NC_007633.1 731978 732712 D identified by match to protein family HMM PF00455; DeoR family transcriptional regulator 731978..732712 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828971 YP_424586.1 CDS MCAP_0618 NC_007633.1 732721 734607 D identified by match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system transporter subunit IIBC 732721..734607 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828878 YP_424587.1 CDS MCAP_0619 NC_007633.1 734620 735561 D identified by similarity to SP:O31714; match to protein family HMM PF00294; 1-phosphofructokinase 734620..735561 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828424 YP_424588.1 CDS MCAP_0620 NC_007633.1 735640 737490 R There are 2 membrane spanning regions in MCAP_0620.; hypothetical protein complement(735640..737490) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828388 YP_424589.1 CDS MCAP_0621 NC_007633.1 738045 738590 R MCAP_0621 has 1 membrane spanning region, N-terminal.; hypothetical protein complement(738045..738590) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828672 YP_424590.1 CDS MCAP_0622 NC_007633.1 740123 741652 D MCAP_0622 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0622 has 1 membrane spanning region, N-terminal; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 740123..741652 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828708 YP_424591.1 CDS MCAP_0623 NC_007633.1 741987 743822 D identified by match to protein family HMM PF00753; match to protein family HMM PF07521; metallo-beta-lactamase superfamily protein 741987..743822 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829145 YP_424592.1 CDS MCAP_0624 NC_007633.1 743900 744853 D MCAP_0624 has 7 membrane spanning regions; hypothetical protein 743900..744853 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828993 YP_424593.1 CDS MCAP_0625 NC_007633.1 745896 747140 D MCAP_0625 has 7 membrane spanning regions; hypothetical protein 745896..747140 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828475 YP_424594.1 CDS MCAP_0626 NC_007633.1 747406 748809 D MCAP_0626 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. There is 1 membrane spanning region in MCAP_0626; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein 747406..748809 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829142 YP_424595.1 CDS MCAP_0627 NC_007633.1 749130 750881 D MCAP_0627 has 2 membrane spanning regions; hypothetical protein 749130..750881 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828910 YP_424596.1 CDS MCAP_0628 NC_007633.1 750894 751562 D MCAP_0628 has 1 membrane spanning region; hypothetical protein 750894..751562 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829054 YP_424597.1 CDS MCAP_0629 NC_007633.1 751744 752391 D Expression of translation product is demonstrated by specific antibody to a synthetic peptide encoded by the ORF. Product partitions in Triton X-114 phase of detergent fractionated organisms, consistent with a cell-associated lipoprotein encoding an otherwise hydrophilic sequence. Product is identified on surface of organism by colony immunostaining. Product is also defined by peptide mass mapping using mass spectrometry. Tandem repeat sequence occurs in the ORF. Tandem nucleotide repeats of TA occur 5' of the ORF in a promoter region; this tract is possibly subject to dinucleotide indels governing phase variable expression of the gene.; lipoprotein VmcE 751744..752391 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828954 YP_424598.1 CDS MCAP_0630 NC_007633.1 753218 753748 D Expression of translation product is demonstrated by specific antibody to a synthetic peptide encoded by the ORF. Product partitions in Triton X-114 phase of detergent fractionated organisms, consistent with a cell-associated lipoprotein encoding an otherwise hydrophilic sequence. Product is identified on surface of organism by colony immunostaining. Product is also defined by peptide mass mapping using mass spectrometry. Tandem repeat sequence occurs in the ORF. Tandem nucleotide repeats of TA occur 5' of the ORF in a promoter region; this tract is possibly subject to dinucleotide indels governing phase variable expression of the gene.; lipoprotein VmcF 753218..753748 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828978 YP_424599.1 CDS pgk NC_007633.1 753818 755032 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(753818..755032) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828670 YP_424600.1 CDS gap NC_007633.1 755160 756176 R identified by similarity to SP:Q59309; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase complement(755160..756176) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828624 YP_424601.1 CDS MCAP_0633 NC_007633.1 756269 757204 R This protein is similar to the B. subtilis DnaI primasomal protein (31% amino acid identity); hypothetical protein complement(756269..757204) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828452 YP_424602.1 CDS MCAP_0634 NC_007633.1 757214 758398 R identified by match to protein family HMM PF07261; hypothetical protein complement(757214..758398) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828764 YP_424603.1 CDS mutM NC_007633.1 758556 759380 R identified by similarity to SP:P42371; match to protein family HMM PF01149; match to protein family HMM PF06831; match to protein family HMM TIGR00577; formamidopyrimidine-DNA glycosylase complement(758556..759380) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828580 YP_424604.1 CDS polA NC_007633.1 759391 762126 R identified by similarity to SP:Q04957; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593; DNA polymerase I complement(759391..762126) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828562 YP_424605.1 CDS dnaE NC_007633.1 762135 765095 R identified by match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF07733; match to protein family HMM TIGR00594; DNA-directed DNA polymerase III (polc) complement(762135..765095) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829037 YP_424606.1 CDS MCAP_0638 NC_007633.1 765267 767921 D MCAP_0638 has 2 membrane spanning regions; hypothetical protein 765267..767921 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828449 YP_424607.1 CDS tyrS NC_007633.1 768010 769254 R identified by similarity to SP:P22326; match to protein family HMM PF00579; match to protein family HMM PF01479; match to protein family HMM TIGR00234; tyrosyl-tRNA synthetase complement(768010..769254) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828751 YP_424608.1 CDS MCAP_0640 NC_007633.1 769262 770323 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(769262..770323) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828533 YP_424609.1 CDS MCAP_0641 NC_007633.1 770301 770933 R This protein has a tRNA binding domain, but does not look like a phenylalanine tRNA synthetase as similar genes are annotated in some instances. The tRNA synthetase domain is found in prokaryotic methionyl-tRNA synthetases and phenylalanyl tRNA synthetases; identified by match to protein family HMM PF01588; methionyl/phenylalanyl tRNA synthetase domain-containing protein complement(770301..770933) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828355 YP_424610.1 CDS MCAP_0642 NC_007633.1 770984 771823 D identified by match to protein family HMM PF02645; hypothetical protein 770984..771823 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828622 YP_424611.1 CDS MCAP_0643 NC_007633.1 771834 772685 D identified by match to protein family HMM PF02645; degV family protein 771834..772685 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829012 YP_424612.1 CDS MCAP_0646 NC_007633.1 772982 773449 R identified by similarity to SP:P71086; match to protein family HMM PF01475; FUR family transcriptional regulator complement(772982..773449) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828930 YP_424613.1 CDS MCAP_0647 NC_007633.1 773451 773672 R identified by match to protein family HMM PF00550; acyl carrier protein complement(773451..773672) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828572 YP_424614.1 CDS MCAP_0648 NC_007633.1 773693 774061 R lipoprotein complement(773693..774061) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828418 YP_424615.1 CDS MCAP_0649 NC_007633.1 774048 775115 R The amino terminal 86 amino acids are 77% identical to the M. mycoides SC hypothetical protein MSC_0695. The carboxyl terminal 45 amino acids are 78% identical to the M. mycoides SC hypothetical protein MSC_0694. There is no clear BLASTp match for any of the middle part of the the protein.; hypothetical protein complement(774048..775115) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828885 YP_424616.1 CDS arcC NC_007633.1 775419 776351 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(775419..776351) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828577 YP_424617.1 CDS MCAP_0652 NC_007633.1 776470 777564 R catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase complement(776470..777564) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828849 YP_424618.1 CDS MCAP_0653 NC_007633.1 777571 778989 R identified by similarity to SP:P39183; match to protein family HMM PF00324; amino acid permease family protein complement(777571..778989) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829079 YP_424619.1 CDS argF NC_007633.1 779011 780108 R catalyzes the formation of putrescine from carbamoyl-putrescine during agmatine degradation; putrescine carbamoyltransferase complement(779011..780108) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828588 YP_424620.1 CDS MCAP_0655 NC_007633.1 780339 781226 D This is adjacent to a possible permease that may comprise the rest of this ABC transporter cassette. There is no hint about what the substrate is for this transporter; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 780339..781226 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828852 YP_424621.1 CDS MCAP_0656 NC_007633.1 781228 781992 D This gene has 6 transmembrane regions and is adjacent to an ATP binding protein of a likely ABC transporter cassette. Thus we annotate it as a ABC transporter permease.; ABC transporter permease 781228..781992 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828923 YP_424622.1 CDS MCAP_0657 NC_007633.1 782026 782505 R MCAP_0657 has 2 membrane spanning regions; hypothetical protein complement(782026..782505) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828681 YP_424623.1 CDS MCAP_0658 NC_007633.1 782589 784154 R MCAP_0658 has 8 membrane spanning regions; hypothetical protein complement(782589..784154) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828785 YP_424624.1 CDS leuS NC_007633.1 784221 786635 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(784221..786635) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828466 YP_424625.1 CDS MCAP_0661 NC_007633.1 786903 789746 R lipoprotein complement(786903..789746) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828292 YP_424626.1 CDS rpsI NC_007633.1 789908 790306 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(789908..790306) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828985 YP_424627.1 CDS rplM NC_007633.1 790306 790761 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(790306..790761) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828494 YP_424628.1 CDS MCAP_0664 NC_007633.1 790881 795026 R MCAP_0664 has 8 membrane spanning regions; MCAP_0664 has characteristics of an ABC transporter permease; however it is not near any ATPase; identified by match to protein family HMM PF02687; hypothetical protein complement(790881..795026) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828560 YP_424629.1 CDS truA NC_007633.1 795151 795900 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(795151..795900) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828334 YP_424630.1 CDS MCAP_0666 NC_007633.1 795902 796912 R Part of a 3 gene ABC transporter cassette. There is no substrate binding protein evident; identified by match to protein family HMM PF02361; cobalt ABC transporter permease complement(795902..796912) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828867 YP_424631.1 CDS cbiO NC_007633.1 796925 797794 R with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(796925..797794) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828435 YP_424632.1 CDS cbiO NC_007633.1 797821 799047 R with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(797821..799047) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828537 YP_424633.1 CDS rplQ NC_007633.1 799158 799517 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(799158..799517) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828717 YP_424634.1 CDS rpoA NC_007633.1 799537 800490 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(799537..800490) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828381 YP_424635.1 CDS rpsK NC_007633.1 800494 800883 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(800494..800883) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829035 YP_424636.1 CDS rpsM NC_007633.1 800909 801274 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(800909..801274) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828578 YP_424637.1 CDS rpmJ NC_007633.1 801312 801425 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(801312..801425) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828811 YP_424638.1 CDS infA NC_007633.1 801495 801719 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(801495..801719) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828748 YP_424639.1 CDS map NC_007633.1 801731 802486 R identified by similarity to SP:P19994; match to protein family HMM PF00557; match to protein family HMM TIGR00500; methionine aminopeptidase complement(801731..802486) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829108 YP_424640.1 CDS adk NC_007633.1 802486 803127 R identified by similarity to SP:P16304; match to protein family HMM PF00406; match to protein family HMM PF05191; match to protein family HMM TIGR01351; adenylate kinase complement(802486..803127) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828966 YP_424641.1 CDS secY NC_007633.1 803256 804704 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(803256..804704) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829068 YP_424642.1 CDS rplO NC_007633.1 804704 805141 R late assembly protein; 50S ribosomal protein L15 complement(804704..805141) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828415 YP_424643.1 CDS rpsE NC_007633.1 805161 805925 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(805161..805925) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828832 YP_424644.1 CDS rplR NC_007633.1 805944 806294 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(805944..806294) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829120 YP_424645.1 CDS rplF NC_007633.1 806320 806862 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(806320..806862) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828389 YP_424646.1 CDS rpsH NC_007633.1 806876 807265 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(806876..807265) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828925 YP_424647.1 CDS rpsN NC_007633.1 807287 807472 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 complement(807287..807472) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828693 YP_424648.1 CDS rplE NC_007633.1 807491 808033 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(807491..808033) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828999 YP_424649.1 CDS rplX NC_007633.1 808052 808378 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(808052..808378) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828633 YP_424650.1 CDS rplN NC_007633.1 808392 808760 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(808392..808760) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829019 YP_424651.1 CDS rpsQ NC_007633.1 808776 809033 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(808776..809033) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828534 YP_424652.1 CDS rpmC NC_007633.1 809033 809449 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(809033..809449) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828552 YP_424653.1 CDS rplP NC_007633.1 809449 809862 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(809449..809862) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828986 YP_424654.1 CDS rpsC NC_007633.1 809865 810566 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(809865..810566) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828839 YP_424655.1 CDS rplV NC_007633.1 810584 810919 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(810584..810919) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828295 YP_424656.1 CDS rpsS NC_007633.1 810943 811209 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(810943..811209) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829121 YP_424657.1 CDS rplB NC_007633.1 811231 812076 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(811231..812076) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829089 YP_424658.1 CDS rplW NC_007633.1 812129 812413 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(812129..812413) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828500 YP_424659.1 CDS rplD NC_007633.1 812413 813039 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(812413..813039) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828469 YP_424660.1 CDS rplC NC_007633.1 813052 813723 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(813052..813723) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828671 YP_424661.1 CDS rpsJ NC_007633.1 813798 814106 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(813798..814106) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828323 YP_424662.1 CDS MCAP_0698 NC_007633.1 814402 815400 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(814402..815400) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828620 YP_424663.1 CDS MCAP_0699 NC_007633.1 815710 816549 D MCAP_0699 has 6 membrane spanning regions; hypothetical protein 815710..816549 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828915 YP_424664.1 CDS MCAP_0704 NC_007633.1 817226 818425 R This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein complement(817226..818425) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829013 YP_424665.1 CDS MCAP_0705 NC_007633.1 818538 819233 R MCAP_0705 has 3 membrane spanning regions; hypothetical protein complement(818538..819233) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829045 YP_424666.1 CDS folD NC_007633.1 819238 820092 R MCAP_0706 has 50% identity to characterized E. coli folD protein. Also has EC number of 3.5.4.9 for methenyltetrahydrofolate cyclohydrolase activity; identified by match to protein family HMM PF00763; match to protein family HMM PF02882; methylene-tetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase complement(819238..820092) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829076 YP_424667.1 CDS MCAP_0707 NC_007633.1 820101 821702 R This gene and the one downstream are both likely potassium ion transporters of the Trk transporter family. The are on opposite strands; identified by similarity to PIR:B70007; match to protein family HMM PF02386; TrkH family potassium uptake protein complement(820101..821702) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828877 YP_424668.1 CDS MCAP_0708 NC_007633.1 821781 822509 D This gene and the one upstream are both likely cation transporters of the Trk transporter family. The are on opposite strands; identified by similarity to SP:P39760; match to protein family HMM PF02080; match to protein family HMM PF02254; TrkA family potassium uptake protein 821781..822509 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828847 YP_424669.1 CDS gatB NC_007633.1 822546 823985 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(822546..823985) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828834 YP_424670.1 CDS gatA NC_007633.1 823987 825444 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(823987..825444) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828338 YP_424671.1 CDS gatC NC_007633.1 825444 825740 R identified by similarity to GP:2465557; match to protein family HMM PF02686; match to protein family HMM TIGR00135; glutamyl-tRNA(Gln) amidotransferase subunit C complement(825444..825740) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828453 YP_424672.1 CDS ligA NC_007633.1 825742 827748 R identified by similarity to SP:P49421; match to protein family HMM PF00533; match to protein family HMM PF00633; match to protein family HMM PF01653; match to protein family HMM PF03119; match to protein family HMM PF03120; match to protein family HMM TIGR00575; NAD-dependent DNA ligase complement(825742..827748) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829023 YP_424673.1 CDS MCAP_0713 NC_007633.1 827752 829752 R MCAP_0713 has 14 membrane spanning regions; hypothetical protein complement(827752..829752) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828547 YP_424674.1 CDS MCAP_0714 NC_007633.1 829755 830663 R identified by match to protein family HMM PF00849; match to protein family HMM PF01479; ribosomal large subunit pseudouridine synthase A complement(829755..830663) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828946 YP_424675.1 CDS MCAP_0715 NC_007633.1 830666 831676 R MCAP_0715 has 9 transmembrane regions; identified by match to protein family HMM PF02517; CAAX amino terminal protease family protein complement(830666..831676) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828615 YP_424676.1 CDS ptsH NC_007633.1 831735 832004 R The M. capricolum Hpr protein was characterized in: Zhu PP, Reizer J, Reizer A, Peterkofsky A. 1993. 'Unique monocistronic operon (ptsH) in Mycoplasma capricolum encoding the phosphocarrier protein, HPr, of the phosphoenolpyruvate:sugar phosphotransferase system. Cloning, sequencing, and characterization of ptsH'. Unique monocistronic operon (ptsH) in Mycoplasma capricolum encoding the phosphocarrier protein, HPr, of the phosphoenolpyruvate:sugar phosphotransferase system. Cloning, sequencing, and characterization of ptsH. J Biol Chem. 268(35):26531-40; identified by similarity to SP:P45611; match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr complement(831735..832004) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828959 YP_424677.1 CDS pcrA NC_007633.1 832070 834238 R identified by similarity to SP:P56255; match to protein family HMM PF00580; ATP-dependent DNA helicase pcrA complement(832070..834238) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828917 YP_424678.1 CDS MCAP_0718 NC_007633.1 834250 834996 R MCAP_0718 has 4 membrane spanning regions; identified by match to protein family HMM PF06271; hypothetical protein complement(834250..834996) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828611 YP_424679.1 CDS MCAP_0719 NC_007633.1 834996 835952 R In the absence of evidence for cell wall or lipopolysccharide synthesis in mycoplasmas, or capsule synthesis in M. capricolum subsp capricolum Kid, the role category 'biosynthesis/degradation of surface polysaccharides and lipopolysaccharides' is assigned to foster comparison with genes having possible capsule-associated functions in other organisms of the Mycoplasma mycoides phylogenetic cluster; identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(834996..835952) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828344 YP_424680.1 CDS MCAP_0720 NC_007633.1 836066 837283 R This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein complement(836066..837283) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829017 YP_424681.1 CDS MCAP_0721 NC_007633.1 837411 838655 R This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein complement(837411..838655) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828687 YP_424682.1 CDS MCAP_0722 NC_007633.1 838759 839688 R N-terminal section belongs to the msrA Met sulfoxide reductase family, and the C-terminal section belongs to the msrB Met sulfoxide reductase family; identified by similarity to SP:P35593; match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase msrA/msrB complement(838759..839688) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828963 YP_424683.1 CDS MCAP_0723 NC_007633.1 839804 842017 R lipoprotein complement(839804..842017) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828703 YP_424684.1 CDS MCAP_0724 NC_007633.1 842026 842931 R MCAP_0724 has 7 membrane spanning regions; hypothetical protein complement(842026..842931) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828783 YP_424685.1 CDS MCAP_0725 NC_007633.1 843048 844337 R This protein is similar to Ureaplasma parvum proteins UU527 and UU090. They all fall into COG1479, which is described as 'uncharacterized ACR'; identified by match to protein family HMM PF07510; hypothetical protein complement(843048..844337) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828684 YP_424686.1 CDS MCAP_0726 NC_007633.1 844625 845593 R The amino terminal 190 amino acids of this protein are 32 identical to M. mycoides SC hypothetical protein MSC_0779 and the carboxyl end is similar to the adjacent M. mcyoides SC protein MSC_0780.; hypothetical protein complement(844625..845593) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829048 YP_424687.1 CDS MCAP_0727 NC_007633.1 845783 848155 R lipoprotein complement(845783..848155) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828626 YP_424688.1 CDS MCAP_0728 NC_007633.1 848167 849066 R MCAP_0728 has 6 membrane spanning regions; hypothetical protein complement(848167..849066) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828610 YP_424689.1 CDS MCAP_0729 NC_007633.1 849165 850913 R Adjacent to likely ATPase and substrate binding proteins; identified by similarity to SP:P15362; match to protein family HMM PF00528; ABC transporter permease p69 complement(849165..850913) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828528 YP_424690.1 CDS MCAP_0730 NC_007633.1 850877 851626 R Similar to ATP-binding protein p29 of Mycoplasma hyorhinis; identified by similarity to SP:P15361; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(850877..851626) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828979 YP_424691.1 CDS MCAP_0731 NC_007633.1 851627 853087 R Adjacent to likely permease and ATP binding proteins; identified by similarity to SP:P15363; ABC transporter substrate-binding protein complement(851627..853087) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828752 YP_424692.1 CDS MCAP_0732 NC_007633.1 853320 854183 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; cof family hydrolase complement(853320..854183) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828698 YP_424693.1 CDS MCAP_0733 NC_007633.1 854317 855510 D identified by similarity to SP:Q08432; match to protein family HMM PF00155; aminotransferase, classes I and II 854317..855510 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828974 YP_424694.1 CDS MCAP_0734 NC_007633.1 855520 855921 D identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP 855520..855921 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828908 YP_424695.1 CDS MCAP_0735 NC_007633.1 855962 857209 R MCAP_0735 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0735 has 1 membrane spanning region (C-terminal)and one region scored only as a signal peptide (N-terminal). In this regard, it may have 2 membrane spanning regions, similar to closely related paralogs MCAP_0738, MCAP_0737, MCAP_0736; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(855962..857209) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828434 YP_424696.1 CDS MCAP_0736 NC_007633.1 857413 858684 R MCAP_0736 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. There are 2 membrane spanning regions in MCAP_0736; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(857413..858684) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828835 YP_424697.1 CDS MCAP_0737 NC_007633.1 858892 860133 R MCAP_0737 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. There are 2 membrane spanning regions in MCAP_0737; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(858892..860133) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828872 YP_424698.1 CDS MCAP_0738 NC_007633.1 860356 861696 R MCAP_0738 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0738 has 1 membrane spanning region (C-terminal)and one region scored only as a signal peptide (N-terminal). In this regard, it may have 2 membrane spanning regions, similar to closely related paralogs MCAP_0737, MCAP_0736, MCAP_0735; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(860356..861696) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828842 YP_424699.1 CDS MCAP_0739 NC_007633.1 861836 862984 D hypothetical protein 861836..862984 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828618 YP_424700.1 CDS nagB1 NC_007633.1 864129 864857 D MCAP_0128 nagB2 is a paralog of MCAP_0749; identified by similarity to SP:O35000; match to protein family HMM PF01182; match to protein family HMM TIGR00502; glucosamine-6-phosphate isomerase 864129..864857 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828765 YP_424701.1 CDS tpiA NC_007633.1 864962 865708 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 864962..865708 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828559 YP_424702.1 CDS MCAP_0751 NC_007633.1 865701 866537 D identified by match to protein family HMM TIGR01484; HAD family hydrolase 865701..866537 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828489 YP_424703.1 CDS gpmI NC_007633.1 866540 868135 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 866540..868135 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828629 YP_424704.1 CDS MCAP_0753 NC_007633.1 868232 868831 D hypothetical protein 868232..868831 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828365 YP_424705.1 CDS MCAP_0754 NC_007633.1 868833 869831 D hypothetical protein 868833..869831 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829063 YP_424706.1 CDS deoC NC_007633.1 869897 870565 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(869897..870565) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828791 YP_424707.1 CDS MCAP_0756 NC_007633.1 870577 872259 R identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; phosphoglucomutase/phosphomannomutase complement(870577..872259) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828827 YP_424708.1 CDS deoA NC_007633.1 872424 873737 D identified by similarity to SP:P77836; match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831; match to protein family HMM TIGR02644; pyrimidine-nucleoside phosphorylase 872424..873737 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828903 YP_424709.1 CDS MCAP_0758 NC_007633.1 873824 875980 R lipoprotein complement(873824..875980) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828318 YP_424710.1 CDS mgtE NC_007633.1 876647 878050 D identified by similarity to OMNI:SA1013; match to protein family HMM PF00571; match to protein family HMM PF03448; match to protein family HMM TIGR00400; magnesium transporter 876647..878050 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828542 YP_424711.1 CDS trmB NC_007633.1 878052 878714 D identified by match to protein family HMM PF02390; match to protein family HMM TIGR00091; tRNA (guanine-N(7)-)-methyltransferase 878052..878714 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828895 YP_424712.1 CDS MCAP_0762 NC_007633.1 879090 879680 R MCAP_0762 has 2 membrane spanning regions; hypothetical protein complement(879090..879680) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828585 YP_424713.1 CDS MCAP_0763 NC_007633.1 879834 880520 R MCAP_0763 encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif. MCAP_0763 has 1 membrane spanning region, N-terminal; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; hypothetical protein complement(879834..880520) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828589 YP_424714.1 CDS MCAP_0764 NC_007633.1 880855 880977 R hypothetical protein complement(880855..880977) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829038 YP_424715.1 CDS hpt2 NC_007633.1 881281 881832 R MCAP_0216 (hpt1) is a paralog of MCAP_0765; identified by similarity to SP:Q02522; match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase complement(881281..881832) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829123 YP_424716.1 CDS purB NC_007633.1 881855 883153 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(881855..883153) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828321 YP_424717.1 CDS purA NC_007633.1 883146 884444 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(883146..884444) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829074 YP_424718.1 CDS MCAP_0768 NC_007633.1 884729 885529 R identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; TatD family deoxyribonuclease complement(884729..885529) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828711 YP_424719.1 CDS MCAP_0770 NC_007633.1 885990 887348 D This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein 885990..887348 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828592 YP_424720.1 CDS MCAP_0771 NC_007633.1 887434 888903 R MCAP_0771 has 4 membrane spanning regions; hypothetical protein complement(887434..888903) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828745 YP_424721.1 CDS MCAP_0772 NC_007633.1 888906 889856 R identified by match to protein family HMM TIGR01128; hypothetical protein complement(888906..889856) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828781 YP_424722.1 CDS uvrB NC_007633.1 890143 892140 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 890143..892140 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828351 YP_424723.1 CDS uvrA NC_007633.1 892149 894989 D identified by similarity to SP:O34863; match to protein family HMM PF00005; match to protein family HMM TIGR00630; excinuclease ABC subunit A 892149..894989 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828420 YP_424724.1 CDS folC NC_007633.1 894982 896091 D identified by similarity to GP:12724120; match to protein family HMM TIGR01499; folate synthetase-polyglutamyl folate synthetase 894982..896091 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828593 YP_424725.1 CDS MCAP_0776 NC_007633.1 896119 896793 D MCAP_0776 has 6 membrane spanning regions; hypothetical protein 896119..896793 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828935 YP_424726.1 CDS MCAP_0777 NC_007633.1 896874 897815 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 896874..897815 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828431 YP_424727.1 CDS lgt1 NC_007633.1 897826 899406 D MCAP_0780 (lgt2) is a paralog of MCAP_0778; identified by match to protein family HMM PF01790; prolipoprotein diacylglyceryl transferase 897826..899406 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828291 YP_424728.1 CDS trxB NC_007633.1 899390 900322 D identified by similarity to SP:P80880; match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin reductase 899390..900322 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828468 YP_424729.1 CDS lgt2 NC_007633.1 900331 901761 D MCAP_0780 spans a region homologous to a region of M. mycoides SC (MSC) annotated as [ORF MSC_937-intergenic region - ORF MSC_936]. A deletion of a T residue in the MSC genome at nt 1063522-1063524 (three adjacent T residues)would cause a frameshift that would create a single long ORF in MSC corresponding to MCAP780. The corresponding locus of that frameshift in M. capricolum is at 900812-900813(two adjacent T residues). MCAP_0780 represents a second paralog of lgt in M. capricolum; although the HMM TIGR score is below trusted cutoff. MCAP_0778, the other M. capricolum lgt gene, has a better score. MCAP_0778 and MCAP_0780 are reciprocal and significant best hits by BLASTp. ORFs adjacent to MCAP_0778 and MCAP_0780 are not paralogous by BLASTp; identified by similarity to SP:O34752; match to protein family HMM PF01790; prolipoprotein diacylglyceryl transferase 900331..901761 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828358 YP_424730.1 CDS MCAP_0781 NC_007633.1 901773 902702 D identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 901773..902702 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828705 YP_424731.1 CDS MCAP_0782 NC_007633.1 903025 904158 R This ORF encodes tandem sequences containing the lppQ-Variable-Repeat-Peptide motif; identified by match to protein family HMM PF03382; match to protein family HMM TIGR02167; lipoprotein complement(903025..904158) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828637 YP_424732.1 CDS MCAP_0783 NC_007633.1 904220 905842 R identified by similarity to SP:P19642; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system transporter subunit IIBC complement(904220..905842) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828813 YP_424733.1 CDS MCAP_0784 NC_007633.1 905894 906124 R MCAP_0784 has 2 membrane spanning regions; hypothetical protein complement(905894..906124) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828437 YP_424734.1 CDS MCAP_0785 NC_007633.1 906114 906833 R hypothetical protein complement(906114..906833) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828983 YP_424735.1 CDS MCAP_0786 NC_007633.1 906833 907342 R hypothetical protein complement(906833..907342) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828307 YP_424736.1 CDS MCAP_0787 NC_007633.1 907342 909021 R identified by similarity to SP:P20166; match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system transporter subunit IIBC complement(907342..909021) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828400 YP_424737.1 CDS MCAP_0788 NC_007633.1 909644 909811 D identified by similarity to SP:P44978; DeoR family transcriptional regulator 909644..909811 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828635 YP_424738.1 CDS MCAP_0789 NC_007633.1 909935 910906 D hypothetical protein 909935..910906 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829105 YP_424739.1 CDS MCAP_0790 NC_007633.1 911127 912845 D This protein has a low confidence match to the B domain of staphylococcal protein A, which specifically binds to the Fc portion of immunoglobulin G.; hypothetical protein 911127..912845 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829131 YP_424740.1 CDS MCAP_0791 NC_007633.1 912884 913699 R hypothetical protein complement(912884..913699) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828826 YP_424741.1 CDS topA NC_007633.1 913892 915823 D identified by similarity to SP:P39814; match to protein family HMM PF01131; match to protein family HMM PF01396; match to protein family HMM PF01751; DNA topoisomerase I 913892..915823 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828436 YP_424742.1 CDS MCAP_0794 NC_007633.1 916628 917509 R MCAP_0794 has 1 membrane spanning region, N-terminal.; hypothetical protein complement(916628..917509) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828870 YP_424743.1 CDS MCAP_0795 NC_007633.1 917496 918311 R MCAP_0795 has one membrane spanning region, N-terminal.; hypothetical protein complement(917496..918311) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828368 YP_424744.1 CDS MCAP_0796 NC_007633.1 918301 919653 R The single transmembrane region in this ORF may contain a lipoprotein signal motif. Ortholog in in M. mycoides SC is annotated as a prolipoprotein.; lipoprotein complement(918301..919653) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828283 YP_424745.1 CDS MCAP_0797 NC_007633.1 919631 920335 R The adjacent ORF is a likely permease, and also part of this apparant operon are several lipoproteins that could possibly be substrate binding proteins; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(919631..920335) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828887 YP_424746.1 CDS MCAP_0798 NC_007633.1 920337 922202 R This is part of a likely operon with an ABC transporter ATPase, and several lipoproteins that might be substrate binding proteins.; ABC transporter permease complement(920337..922202) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829077 YP_424747.1 CDS MCAP_0799 NC_007633.1 922342 923238 R This lipoprotein is part of likely ABC transporter operon. The next two genes in the operon encode a likely permease and a clear ATPase.; lipoprotein complement(922342..923238) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828746 YP_424748.1 CDS MCAP_0800 NC_007633.1 923231 924070 R MCAP_0800 has 1 membrane spanning region, N-terminal.; hypothetical protein complement(923231..924070) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828541 YP_424749.1 CDS MCAP_0801 NC_007633.1 924057 925010 R lipoprotein complement(924057..925010) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829058 YP_424750.1 CDS MCAP_0802 NC_007633.1 925029 926867 R MCAP_0802 has 6 membrane spanning regions; hypothetical protein complement(925029..926867) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828881 YP_424751.1 CDS MCAP_0803 NC_007633.1 926975 928741 R These proteins are members of the C4-dicarboxylate Uptake C (DcuC) family. DcuC has 12 GES predicted transmembrane regions, is induced only under anaerobic conditions, and is not repressed by glucose. DcuC may therefore function as a succinate efflux system during anaerobic glucose fermentation; identified by match to protein family HMM PF03606; C4-dicarboxylate anaerobic carrier complement(926975..928741) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828807 YP_424752.1 CDS MCAP_0804 NC_007633.1 928810 929499 R identified by match to protein family HMM PF01863; zinc metalloprotease complement(928810..929499) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828352 YP_424753.1 CDS engD NC_007633.1 929506 930600 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(929506..930600) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828376 YP_424754.1 CDS MCAP_0806 NC_007633.1 930636 930836 R hypothetical protein complement(930636..930836) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829031 YP_424755.1 CDS gidB NC_007633.1 930838 931533 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(930838..931533) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828396 YP_424756.1 CDS pgsA NC_007633.1 931533 932129 R identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(931533..932129) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828951 YP_424757.1 CDS MCAP_0810 NC_007633.1 933920 934603 R MCAP_0810 has 6 membrane spanning regions; hypothetical protein complement(933920..934603) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828779 YP_424758.1 CDS MCAP_0811 NC_007633.1 934569 936116 R Orthologs of MCAP_0811 are often annotated as permeases for amino acid transport. There is no convincing wet science or sequence-based evidence for this. MCAP_0811 has 12 membrane spanning regions; identified by match to protein family HMM PF00324; hypothetical protein complement(934569..936116) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828968 YP_424759.1 CDS MCAP_0812 NC_007633.1 936175 938910 R identified by similarity to SP:P39168; match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; magnesium-transporting ATPase E1-E2 family protein complement(936175..938910) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828304 YP_424760.1 CDS hup NC_007633.1 938918 939544 R Start site prediction is difficult for this gene. The B. subtilis ortholog is much smaller, with 38% identity between amino acids 129-206 of this 208 amino acid protein. A start site with a good ribosome binding site was chosen; identified by similarity to SP:P08821; match to protein family HMM PF00216; DNA-binding protein HU complement(938918..939544) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828969 YP_424761.1 CDS MCAP_0814 NC_007633.1 940433 941860 R This protein has 12 membrane spanning regions and matches COG0477 (permeases of the major facilitator superfamily); identified by similarity to OMNI:NTL02MM0861; match to protein family HMM PF07672; match to protein family HMM PF07690; transporter protein complement(940433..941860) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828474 YP_424762.1 CDS MCAP_0815 NC_007633.1 942121 943695 R MCAP_0815 has 8 membrane spanning regions; hypothetical protein complement(942121..943695) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828901 YP_424763.1 CDS MCAP_0816 NC_007633.1 943860 944483 R This gene shares strong identity to two three gene clusters in Mycoplasma mycoides SC.; hypothetical protein complement(943860..944483) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828676 YP_424764.1 CDS asnA NC_007633.1 944540 945520 R catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA complement(944540..945520) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829008 YP_424765.1 CDS rpsT NC_007633.1 945932 946177 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 945932..946177 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828902 YP_424766.1 CDS trmE NC_007633.1 946228 947586 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(946228..947586) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828863 YP_424767.1 CDS MCAP_0820 NC_007633.1 947790 948014 D hypothetical protein 947790..948014 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828341 YP_424768.1 CDS MCAP_0821 NC_007633.1 948123 949082 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 948123..949082 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828879 YP_424769.1 CDS MCAP_0822 NC_007633.1 949106 950236 D hypothetical protein 949106..950236 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828801 YP_424770.1 CDS MCAP_0823 NC_007633.1 950247 951086 D identified by match to protein family HMM TIGR00099; HAD superfamily hydrolase 950247..951086 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828756 YP_424771.1 CDS asnC NC_007633.1 951095 952459 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 951095..952459 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828302 YP_424772.1 CDS MCAP_0825 NC_007633.1 952728 954092 D This is adjacent to two other phosphonate ABC transporter elements. The annotation is based on the gene being part of a likely ABC transporter operon and the presence of a lipoprotein attachment site and likely signal peptide.; phosphonate ABC transporter phosphonate-binding protein 952728..954092 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828555 YP_424773.1 CDS MCAP_0826 NC_007633.1 954106 954858 D Part of a likely 3 gene ABC transporter cassette operon; identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315; phosphonate ABC transporter ATP-binding protein 954106..954858 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828538 YP_424774.1 CDS MCAP_0827 NC_007633.1 954862 957597 D Member of Phosphonate Uptake Transporter (PhnT) Family. This is an element of a likely 3 gene ABC transporter cassette operon; identified by similarity to SP:P16683; match to protein family HMM PF00528; match to protein family HMM TIGR01097; alkylphosphonate ABC transporter permease 954862..957597 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829056 YP_424775.1 CDS MCAP_0828 NC_007633.1 957622 959688 R This protein is similar to the characterized Bl subtilis DNA internalization-related competence protein ComEC/Rec2; however because M. capricolum is not competent we elected not to annotate the gene as a comEC related gene.; metallo-beta-lactamase superfamily protein complement(957622..959688) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828354 YP_424776.1 CDS MCAP_0834 NC_007633.1 965268 966110 D identified by match to protein family HMM TIGR01484; HAD superfamily hydrolase 965268..966110 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828619 YP_424777.1 CDS trxA NC_007633.1 966122 966430 D identified by similarity to SP:P14949; match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 966122..966430 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829051 YP_424778.1 CDS lysS NC_007633.1 966562 968064 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(966562..968064) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828398 YP_424779.1 CDS dus NC_007633.1 968067 968993 R This protein has >40% identity to the E. coli tRNA-dihydrouridine synthase protein YhdG; identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase complement(968067..968993) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828346 YP_424780.1 CDS MCAP_0838 NC_007633.1 969043 969357 R hypothetical protein complement(969043..969357) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829095 YP_424781.1 CDS serS NC_007633.1 969451 970719 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(969451..970719) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829096 YP_424782.1 CDS MCAP_0840 NC_007633.1 970800 971627 R MCAP_0840 has 6 membrane spanning regions; hypothetical protein complement(970800..971627) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828298 YP_424783.1 CDS MCAP_0841 NC_007633.1 971695 972279 R hypothetical protein complement(971695..972279) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829006 YP_424784.1 CDS MCAP_0842 NC_007633.1 972298 972588 R MCAP_0842 has 2 membrane spanning regions; hypothetical protein complement(972298..972588) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829021 YP_424785.1 CDS MCAP_0843 NC_007633.1 972758 974992 D lipoprotein 972758..974992 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828553 YP_424786.1 CDS MCAP_0844 NC_007633.1 975036 976778 R identified by similarity to SP:P20166; match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system glucose-specific IIBC component complement(975036..976778) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828598 YP_424787.1 CDS bcp NC_007633.1 976887 977321 D identified by match to protein family HMM PF00578; bacterioferritin comigratory protein 976887..977321 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828479 YP_424788.1 CDS MCAP_0846 NC_007633.1 977485 979575 D lipoprotein 977485..979575 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828602 YP_424789.1 CDS MCAP_0847 NC_007633.1 980325 981230 D hypothetical protein 980325..981230 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828775 YP_424790.1 CDS MCAP_0848 NC_007633.1 981284 981748 D identified by similarity to GB:CAE77252.1; transposase IS1296EH (ORFA) 981284..981748 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828359 YP_424791.1 CDS deoD NC_007633.1 981796 982449 R identified by similarity to SP:O34925; match to protein family HMM PF01048; purine nucleoside phosphorylase complement(981796..982449) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828707 YP_424792.1 CDS MCAP_0850 NC_007633.1 982682 983662 R hypothetical protein complement(982682..983662) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828496 YP_424793.1 CDS MCAP_0851 NC_007633.1 983814 984512 D Gene is adjacent to fructose metabolism and transport genes; identified by match to protein family HMM PF00455; fructose operon transcriptional regulator 983814..984512 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828369 YP_424794.1 CDS MCAP_0852 NC_007633.1 984512 985447 D identified by similarity to SP:O31714; match to protein family HMM PF00294; 1-phosphofructokinase 984512..985447 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828726 YP_424795.1 CDS fruA NC_007633.1 985450 987486 D identified by similarity to SP:P47308; match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427; PTS system fructose-specific transporter subunit IIABC 985450..987486 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828819 YP_424796.1 CDS MCAP_0854 NC_007633.1 988122 988697 D hypothetical protein 988122..988697 Mycoplasma capricolum subsp. capricolum ATCC 27343 3829078 YP_424797.1 CDS MCAP_0855 NC_007633.1 988866 989453 D hypothetical protein 988866..989453 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828444 YP_424798.1 CDS gidA NC_007633.1 989799 991688 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(989799..991688) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828821 YP_424799.1 CDS MCAP_0857 NC_007633.1 991832 993400 R identified by match to protein family HMM PF00375; proton/glutamate symporter family protein complement(991832..993400) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828742 YP_424800.1 CDS MCAP_0858 NC_007633.1 993422 994765 R MCAP_0858 is a paralog of MCAP_0223. This is a likely NADH oxidase; identified by similarity to SP:P37061; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase complement(993422..994765) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828529 YP_424801.1 CDS pncA NC_007633.1 994986 995486 D identified by similarity to SP:P21369; match to protein family HMM PF00857; pyrazinamidase/nicotinamidase 994986..995486 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828714 YP_424802.1 CDS MCAP_0860 NC_007633.1 995719 997977 R MCAP_0860 has 1 membrane spanning region, N-terminal; hypothetical protein complement(995719..997977) Mycoplasma capricolum subsp. capricolum ATCC 27343 3829060 YP_424803.1 CDS MCAP_0861 NC_007633.1 997987 1000248 R MCAP_0861 has 1 transmembrane region.; hypothetical protein complement(997987..1000248) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828614 YP_424804.1 CDS MCAP_0862 NC_007633.1 1000520 1002772 R MCAP_0862 has 1 membrane spanning region, N-terminal. This protein has 9 copies of a KID repeat as found in Borrelia spirochete RepA / Rep+ proteins, and 5 copies of a Streptococcal M protein repeat.; hypothetical protein complement(1000520..1002772) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828980 YP_424805.1 CDS MCAP_0863 NC_007633.1 1002796 1003617 R hypothetical protein complement(1002796..1003617) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828685 YP_424806.1 CDS MCAP_0864 NC_007633.1 1003625 1005037 R There are 4 paralogous genes in M. capricolum; hypothetical protein complement(1003625..1005037) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828315 YP_424807.1 CDS MCAP_0865 NC_007633.1 1005242 1006399 R MCAP_0865 has 8 membrane spanning regions; hypothetical protein complement(1005242..1006399) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828989 YP_424808.1 CDS MCAP_0866 NC_007633.1 1006457 1007173 R hypothetical protein complement(1006457..1007173) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828855 YP_424809.1 CDS MCAP_0867 NC_007633.1 1007173 1007970 R identified by match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; cof family hydrolase complement(1007173..1007970) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828425 YP_424810.1 CDS MCAP_0868 NC_007633.1 1008050 1009216 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC complement(1008050..1009216) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828597 YP_424811.1 CDS rnpA NC_007633.1 1009258 1009587 R identified by similarity to SP:P58031; match to protein family HMM PF00825; match to protein family HMM TIGR00188; ribonuclease P protein component complement(1009258..1009587) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828570 YP_424812.1 CDS rpmH NC_007633.1 1009594 1009728 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1009594..1009728) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828994 MCAP_0062 tRNA MCAP_0062 NC_007633.1 74293 74368 R tRNA-Lys complement(74293..74368) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828662 MCAP_0316 tRNA MCAP_0316 NC_007633.1 380276 380365 D tRNA-Ser 380276..380365 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828519 MCAP_0331 tRNA MCAP_0331 NC_007633.1 396221 396294 D tRNA-Gly 396221..396294 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828656 MCAP_0404 tRNA MCAP_0404 NC_007633.1 496721 496796 D tRNA-Thr 496721..496796 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828522 MCAP_0405 tRNA MCAP_0405 NC_007633.1 496803 496886 D tRNA-Tyr 496803..496886 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828524 MCAP_0406 tRNA MCAP_0406 NC_007633.1 496894 496968 D tRNA-Gln 496894..496968 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828653 MCAP_0407 tRNA MCAP_0407 NC_007633.1 496973 497048 D tRNA-Lys 496973..497048 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828663 MCAP_0408 tRNA MCAP_0408 NC_007633.1 497057 497145 D tRNA-Leu 497057..497145 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828659 MCAP_0487 tRNA MCAP_0487 NC_007633.1 580100 580184 R tRNA-Leu complement(580100..580184) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828660 MCAP_0535 tRNA MCAP_0535 NC_007633.1 642510 642586 R tRNA-Arg complement(642510..642586) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828654 MCAP_0644 tRNA MCAP_0644 NC_007633.1 772721 772795 R tRNA-Trp complement(772721..772795) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828523 MCAP_0645 tRNA MCAP_0645 NC_007633.1 772833 772908 R tRNA-Sec complement(772833..772908) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828518 MCAP_0650 tRNA MCAP_0650 NC_007633.1 775217 775292 R tRNA-His complement(775217..775292) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828657 MCAP_0660 tRNA MCAP_0660 NC_007633.1 786769 786845 R tRNA-Ile complement(786769..786845) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828658 MCAP_0700 tRNA MCAP_0700 NC_007633.1 816794 816869 R tRNA-Thr complement(816794..816869) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828521 MCAP_0701 tRNA MCAP_0701 NC_007633.1 816882 816957 R tRNA-Val complement(816882..816957) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828525 MCAP_0702 tRNA MCAP_0702 NC_007633.1 816965 817040 R tRNA-Glu complement(816965..817040) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828655 MCAP_0703 tRNA MCAP_0703 NC_007633.1 817048 817123 R tRNA-Asn complement(817048..817123) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828667 MCAP_0740 tRNA MCAP_0740 NC_007633.1 863181 863257 D tRNA-Arg 863181..863257 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828666 MCAP_0741 tRNA MCAP_0741 NC_007633.1 863305 863381 D tRNA-Pro 863305..863381 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828517 MCAP_0742 tRNA MCAP_0742 NC_007633.1 863392 863467 D tRNA-Ala 863392..863467 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828652 MCAP_0743 tRNA MCAP_0743 NC_007633.1 863473 863549 D tRNA-Met 863473..863549 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828665 MCAP_0744 tRNA MCAP_0744 NC_007633.1 863562 863638 D tRNA-Met 863562..863638 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828514 MCAP_0745 tRNA MCAP_0745 NC_007633.1 863680 863772 D tRNA-Ser 863680..863772 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828520 MCAP_0746 tRNA MCAP_0746 NC_007633.1 863795 863870 D tRNA-Met 863795..863870 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828515 MCAP_0747 tRNA MCAP_0747 NC_007633.1 863873 863949 D tRNA-Asp 863873..863949 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828668 MCAP_0748 tRNA MCAP_0748 NC_007633.1 863956 864031 D tRNA-Phe 863956..864031 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828516 MCAP_0769 tRNA MCAP_0769 NC_007633.1 885696 885770 R tRNA-Cys complement(885696..885770) Mycoplasma capricolum subsp. capricolum ATCC 27343 3828651 MCAP_0829 tRNA MCAP_0829 NC_007633.1 959880 959955 D tRNA-Lys 959880..959955 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828664 MCAP_0830 tRNA MCAP_0830 NC_007633.1 959957 960040 D tRNA-Leu 959957..960040 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828661 MCAP_0378 rRNA rrs-1 NC_007633.1 464431 465954 D 16S ribosomal RNA 464431..465954 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828639 MCAP_0379 rRNA rrl-1 NC_007633.1 466184 469077 D 23S ribosomal RNA 466184..469077 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828641 MCAP_0380 rRNA rrf-1 NC_007633.1 469153 469261 D 5S ribosomal RNA 469153..469261 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828643 MCAP_0831 rRNA rrs-2 NC_007633.1 960320 961843 D 16S ribosomal RNA 960320..961843 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828640 MCAP_0832 rRNA rrl-2 NC_007633.1 962075 964968 D 23S ribosomal RNA 962075..964968 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828642 MCAP_0833 rRNA rrf-2 NC_007633.1 965045 965153 D 5S ribosomal RNA 965045..965153 Mycoplasma capricolum subsp. capricolum ATCC 27343 3828644