-- dump date 20120504_153250 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_072661.2 108885075 875454 686..1828 1 NC_000908.2 identified by sequence similarity; DNA polymerase III subunit beta 1828 dnaN 875454 dnaN Mycoplasma genitalium G37 DNA polymerase III subunit beta NP_072661.2 686 D 243273 CDS NP_072662.2 108885076 875221 1828..2760 1 NC_000908.2 identified by sequence similarity; DnaJ domain-containing protein 2760 875221 MG_002 Mycoplasma genitalium G37 DnaJ domain-containing protein NP_072662.2 1828 D 243273 CDS NP_072663.1 12044853 875545 2845..4797 1 NC_000908.2 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4797 gyrB 875545 gyrB Mycoplasma genitalium G37 DNA gyrase subunit B NP_072663.1 2845 D 243273 CDS NP_072664.1 12044854 875558 4812..7322 1 NC_000908.2 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 7322 gyrA 875558 gyrA Mycoplasma genitalium G37 DNA gyrase subunit A NP_072664.1 4812 D 243273 CDS NP_072665.1 12044855 875703 7294..8547 1 NC_000908.2 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 8547 serS 875703 serS Mycoplasma genitalium G37 seryl-tRNA synthetase NP_072665.1 7294 D 243273 CDS NP_072666.1 12044856 875708 8551..9183 1 NC_000908.2 identified by sequence similarity; thymidylate kinase 9183 tmk 875708 tmk Mycoplasma genitalium G37 thymidylate kinase NP_072666.1 8551 D 243273 CDS NP_072667.1 12044857 875716 9156..9920 1 NC_000908.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 9920 875716 MG_007 Mycoplasma genitalium G37 DNA polymerase III subunit delta' NP_072667.1 9156 D 243273 CDS NP_072668.1 12044858 875731 9923..11251 1 NC_000908.2 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 11251 trmE 875731 trmE Mycoplasma genitalium G37 tRNA modification GTPase TrmE NP_072668.1 9923 D 243273 CDS NP_072669.1 12044859 875688 11251..12039 1 NC_000908.2 identified by sequence similarity; TatD family deoxyribonuclease 12039 875688 MG_009 Mycoplasma genitalium G37 TatD family deoxyribonuclease NP_072669.1 11251 D 243273 CDS NP_072670.1 12044860 875714 12068..12724 1 NC_000908.2 identified by sequence similarity; DNA primase-related protein 12724 875714 MG_010 Mycoplasma genitalium G37 DNA primase-related protein NP_072670.1 12068 D 243273 CDS NP_072671.1 12044861 875236 complement(12701..13564) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 13564 875236 MG_011 Mycoplasma genitalium G37 hypothetical protein NP_072671.1 12701 R 243273 CDS NP_072672.1 12044862 875213 complement(13569..14432) 1 NC_000908.2 identified by sequence similarity; alpha-L-glutamate ligase 14432 875213 MG_012 Mycoplasma genitalium G37 alpha-L-glutamate ligase NP_072672.1 13569 R 243273 CDS NP_072673.2 108885077 875696 complement(14395..15216) 1 NC_000908.2 identified by sequence similarity; methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase 15216 folD 875696 folD Mycoplasma genitalium G37 methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase NP_072673.2 14395 R 243273 CDS NP_072674.1 12044864 875485 15555..17426 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein/permease 17426 875485 MG_014 Mycoplasma genitalium G37 ABC transporter ATP-binding protein/permease NP_072674.1 15555 D 243273 CDS NP_072675.1 12044865 875229 17473..19242 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein/permease 19242 875229 MG_015 Mycoplasma genitalium G37 ABC transporter ATP-binding protein/permease NP_072675.1 17473 D 243273 CDS NP_072678.2 108885078 875220 19252..22347 1 NC_000908.2 identified by sequence similarity; SNF2 family helicase 22347 875220 MG_018 Mycoplasma genitalium G37 SNF2 family helicase NP_072678.2 19252 D 243273 CDS NP_072679.1 12044869 875219 22389..23558 1 NC_000908.2 identified by sequence similarity; chaperone protein DnaJ 23558 dnaJ 875219 dnaJ Mycoplasma genitalium G37 chaperone protein DnaJ NP_072679.1 22389 D 243273 CDS NP_072680.1 12044870 875529 23542..24468 1 NC_000908.2 identified by sequence similarity; proline iminopeptidase 24468 pip 875529 pip Mycoplasma genitalium G37 proline iminopeptidase NP_072680.1 23542 D 243273 CDS NP_072681.1 12044871 875451 24468..26006 1 NC_000908.2 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 26006 metS 875451 metS Mycoplasma genitalium G37 methionyl-tRNA synthetase NP_072681.1 24468 D 243273 CDS NP_072682.1 12044872 875707 26036..26473 1 NC_000908.2 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 26473 rpoE 875707 rpoE Mycoplasma genitalium G37 DNA-directed RNA polymerase subunit delta NP_072682.1 26036 D 243273 CDS NP_072683.1 12044873 875427 26479..27345 1 NC_000908.2 identified by sequence similarity; fructose-1,6-bisphosphate aldolase, class II 27345 fba 875427 fba Mycoplasma genitalium G37 fructose-1,6-bisphosphate aldolase, class II NP_072683.1 26479 D 243273 CDS NP_072684.1 12044874 875434 27346..28449 1 NC_000908.2 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 28449 875434 MG_024 Mycoplasma genitalium G37 GTP-dependent nucleic acid-binding protein EngD NP_072684.1 27346 D 243273 CDS NP_072685.1 12044875 875281 28652..29548 1 NC_000908.2 identified by sequence similarity; glycosyl transferase, group 2 family protein 29548 875281 MG_025 Mycoplasma genitalium G37 glycosyl transferase, group 2 family protein NP_072685.1 28652 D 243273 CDS NP_072686.1 12044876 875394 29552..30124 1 NC_000908.2 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 30124 efp 875394 efp Mycoplasma genitalium G37 elongation factor P NP_072686.1 29552 D 243273 CDS NP_072687.1 12044877 875575 30093..30548 1 NC_000908.2 identified by sequence similarity; transcription termination/antitermination protein NusB 30548 875575 MG_027 Mycoplasma genitalium G37 transcription termination/antitermination protein NusB NP_072687.1 30093 D 243273 CDS NP_072688.1 12044878 875284 30548..31153 1 NC_000908.2 identified by sequence similarity; hypothetical protein 31153 875284 MG_028 Mycoplasma genitalium G37 hypothetical protein NP_072688.1 30548 D 243273 CDS NP_072689.1 12044879 875348 complement(31143..31703) 1 NC_000908.2 identified by sequence similarity; DJ-1/PfpI family protein 31703 875348 MG_029 Mycoplasma genitalium G37 DJ-1/PfpI family protein NP_072689.1 31143 R 243273 CDS NP_072690.1 12044880 875326 complement(31705..32325) 1 NC_000908.2 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 32325 upp 875326 upp Mycoplasma genitalium G37 uracil phosphoribosyltransferase NP_072690.1 31705 R 243273 CDS NP_072691.1 12044881 875300 complement(32359..36714) 1 NC_000908.2 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 36714 polC 875300 polC Mycoplasma genitalium G37 DNA polymerase III PolC NP_072691.1 32359 R 243273 CDS NP_072692.1 12044882 875445 36977..38977 1 NC_000908.2 identified by sequence similarity; hypothetical protein 38977 875445 MG_032 Mycoplasma genitalium G37 hypothetical protein NP_072692.1 36977 D 243273 CDS NP_072693.1 12044883 875476 39127..39903 1 NC_000908.2 identified by sequence similarity; glycerol uptake facilitator 39903 glpF 875476 glpF Mycoplasma genitalium G37 glycerol uptake facilitator NP_072693.1 39127 D 243273 CDS NP_072694.1 12044884 875417 complement(39872..40513) 1 NC_000908.2 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 40513 tdk 875417 tdk Mycoplasma genitalium G37 thymidine kinase NP_072694.1 39872 R 243273 CDS NP_072695.1 12044885 875525 40542..41786 1 NC_000908.2 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 41786 hisS 875525 hisS Mycoplasma genitalium G37 histidyl-tRNA synthetase NP_072695.1 40542 D 243273 CDS NP_072696.1 12044886 875228 41776..43428 1 NC_000908.2 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 43428 aspS 875228 aspS Mycoplasma genitalium G37 aspartyl-tRNA synthetase NP_072696.1 41776 D 243273 CDS NP_072697.1 12044887 875280 43401..44753 1 NC_000908.2 identified by sequence similarity; nicotinate phosphoribosyltransferase 44753 875280 MG_037 Mycoplasma genitalium G37 nicotinate phosphoribosyltransferase NP_072697.1 43401 D 243273 CDS NP_072698.1 12044888 875413 complement(44750..46276) 1 NC_000908.2 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 46276 glpK 875413 glpK Mycoplasma genitalium G37 glycerol kinase NP_072698.1 44750 R 243273 CDS NP_072699.1 12044889 875455 complement(46267..47421) 1 NC_000908.2 identified by sequence similarity; FAD-dependent glycerol-3-phosphate dehydrogenase 47421 875455 MG_039 Mycoplasma genitalium G37 FAD-dependent glycerol-3-phosphate dehydrogenase NP_072699.1 46267 R 243273 CDS NP_072700.1 12044890 875216 47580..49355 1 NC_000908.2 identified by sequence similarity; lipoprotein 49355 875216 MG_040 Mycoplasma genitalium G37 lipoprotein NP_072700.1 47580 D 243273 CDS NP_072701.1 12044891 875493 49376..49642 1 NC_000908.2 identified by sequence similarity; phosphocarrier protein HPr 49642 ptsH 875493 ptsH Mycoplasma genitalium G37 phosphocarrier protein HPr NP_072701.1 49376 D 243273 CDS NP_072702.1 12044892 875517 49840..51519 1 NC_000908.2 identified by sequence similarity; spermidine/putrescine ABC transporter ATP-binding protein 51519 potA 875517 potA Mycoplasma genitalium G37 spermidine/putrescine ABC transporter ATP-binding protein NP_072702.1 49840 D 243273 CDS NP_072703.1 12044893 875492 51524..52381 1 NC_000908.2 identified by sequence similarity; spermidine/putrescine ABC transporter permease 52381 potB 875492 potB Mycoplasma genitalium G37 spermidine/putrescine ABC transporter permease NP_072703.1 51524 D 243273 CDS NP_072704.1 12044894 875282 52365..53219 1 NC_000908.2 identified by sequence similarity; spermidine/putrescine ABC transporter permease 53219 potC 875282 potC Mycoplasma genitalium G37 spermidine/putrescine ABC transporter permease NP_072704.1 52365 D 243273 CDS NP_072705.1 12044895 875537 53204..54655 1 NC_000908.2 identified by sequence similarity; spermidine/putrescine ABC transporter spermidine/putrescine binding protein 54655 875537 MG_045 Mycoplasma genitalium G37 spermidine/putrescine ABC transporter spermidine/putrescine binding protein NP_072705.1 53204 D 243273 CDS NP_072706.1 12044896 875433 54657..55604 1 NC_000908.2 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 55604 875433 MG_046 Mycoplasma genitalium G37 DNA-binding/iron metalloprotein/AP endonuclease NP_072706.1 54657 D 243273 CDS NP_072707.1 12044897 875239 55588..56739 1 NC_000908.2 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 56739 metX 875239 metX Mycoplasma genitalium G37 S-adenosylmethionine synthetase NP_072707.1 55588 D 243273 CDS NP_072708.1 12044898 875253 complement(56969..58309) 1 NC_000908.2 identified by sequence similarity; signal recognition particle protein 58309 ffh 875253 ffh Mycoplasma genitalium G37 signal recognition particle protein NP_072708.1 56969 R 243273 CDS NP_072709.2 108885079 875267 58362..59078 1 NC_000908.2 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 59078 deoD 875267 deoD Mycoplasma genitalium G37 purine nucleoside phosphorylase NP_072709.2 58362 D 243273 CDS NP_072710.1 12044900 875446 59082..59753 1 NC_000908.2 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 59753 875446 MG_050 Mycoplasma genitalium G37 deoxyribose-phosphate aldolase NP_072710.1 59082 D 243273 CDS NP_072711.1 12044901 875553 59740..61005 1 NC_000908.2 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 61005 deoA 875553 deoA Mycoplasma genitalium G37 thymidine phosphorylase NP_072711.1 59740 D 243273 CDS NP_072712.1 12044902 875728 61014..61406 1 NC_000908.2 identified by sequence similarity; cytidine deaminase 61406 cdd 875728 cdd Mycoplasma genitalium G37 cytidine deaminase NP_072712.1 61014 D 243273 CDS NP_072713.1 12044903 875706 61406..63058 1 NC_000908.2 identified by sequence similarity; phosphoglucomutase/phosphomannomutase 63058 manB 875706 manB Mycoplasma genitalium G37 phosphoglucomutase/phosphomannomutase NP_072713.1 61406 D 243273 CDS NP_072714.1 12044904 875697 complement(63035..63985) 1 NC_000908.2 identified by sequence similarity; transcription antitermination protein NusG 63985 875697 MG_054 Mycoplasma genitalium G37 transcription antitermination protein NusG NP_072714.1 63035 R 243273 CDS NP_072715.1 12044905 875717 complement(63989..64360) 1 NC_000908.2 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 64360 secE 875717 secE Mycoplasma genitalium G37 preprotein translocase subunit SecE NP_072715.1 63989 R 243273 CDS NP_072716.1 12044906 875514 complement(64367..64513) 1 NC_000908.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 64513 rpmG 875514 rpmG Mycoplasma genitalium G37 50S ribosomal protein L33 NP_072716.1 64367 R 243273 CDS NP_072717.1 12044907 875730 complement(64527..64910) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 64910 875730 MG_474 Mycoplasma genitalium G37 hypothetical protein NP_072717.1 64527 R 243273 CDS NP_072718.1 12044908 875528 complement(64897..65730) 1 NC_000908.2 identified by sequence similarity; tetrapyrrole (corrin/porphyrin) methylase protein 65730 875528 MG_056 Mycoplasma genitalium G37 tetrapyrrole (corrin/porphyrin) methylase protein NP_072718.1 64897 R 243273 CDS NP_072719.1 12044909 875232 complement(65712..66248) 1 NC_000908.2 identified by sequence similarity; small primase-like protein 66248 875232 MG_057 Mycoplasma genitalium G37 small primase-like protein NP_072719.1 65712 R 243273 CDS NP_072720.2 108885080 875549 complement(66227..67225) 1 NC_000908.2 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 67225 prs 875549 prs Mycoplasma genitalium G37 ribose-phosphate pyrophosphokinase NP_072720.2 66227 R 243273 CDS NP_072721.1 12044911 875214 complement(67206..67643) 1 NC_000908.2 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 67643 smpB 875214 smpB Mycoplasma genitalium G37 SsrA-binding protein NP_072721.1 67206 R 243273 CDS NP_072722.1 12044912 875700 67650..68543 1 NC_000908.2 identified by sequence similarity; glycosyl transferase, group 2 family protein 68543 875700 MG_060 Mycoplasma genitalium G37 glycosyl transferase, group 2 family protein NP_072722.1 67650 D 243273 CDS NP_072723.2 108885081 875699 complement(68522..70225) 1 NC_000908.2 identified by sequence similarity; MFS family transporter 70225 875699 MG_061 Mycoplasma genitalium G37 MFS family transporter NP_072723.2 68522 R 243273 CDS NP_072724.1 12044914 875519 70530..72572 1 NC_000908.2 identified by sequence similarity; PTS system, fructose-specific IIABC component 72572 fruA 875519 fruA Mycoplasma genitalium G37 PTS system, fructose-specific IIABC component NP_072724.1 70530 D 243273 CDS NP_072725.2 108885082 875512 72523..73434 1 NC_000908.2 identified by sequence similarity; 1-phosphofructokinase 73434 fruK 875512 fruK Mycoplasma genitalium G37 1-phosphofructokinase NP_072725.2 72523 D 243273 CDS NP_072726.1 12044916 875463 73690..77685 1 NC_000908.2 identified by sequence similarity; ABC transporter permease 77685 875463 MG_064 Mycoplasma genitalium G37 ABC transporter permease NP_072726.1 73690 D 243273 CDS NP_072727.1 12044917 875526 77685..79085 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein 79085 875526 MG_065 Mycoplasma genitalium G37 ABC transporter ATP-binding protein NP_072727.1 77685 D 243273 CDS NP_072728.1 12044918 875474 79089..81035 1 NC_000908.2 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 81035 tktA 875474 tktA Mycoplasma genitalium G37 transketolase NP_072728.1 79089 D 243273 CDS NP_072729.1 12044919 875456 81046..82596 1 NC_000908.2 identified by sequence similarity; lipoprotein 82596 875456 MG_067 Mycoplasma genitalium G37 lipoprotein NP_072729.1 81046 D 243273 CDS NP_072730.1 12044920 875504 82620..84044 1 NC_000908.2 identified by sequence similarity; lipoprotein 84044 875504 MG_068 Mycoplasma genitalium G37 lipoprotein NP_072730.1 82620 D 243273 CDS NP_072731.1 12044921 875466 88228..90954 1 NC_000908.2 identified by sequence similarity; PTS system, glucose-specific IIABC component 90954 ptsG 875466 ptsG Mycoplasma genitalium G37 PTS system, glucose-specific IIABC component NP_072731.1 88228 D 243273 CDS NP_072732.1 12044922 875215 91065..91919 1 NC_000908.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 91919 rpsB 875215 rpsB Mycoplasma genitalium G37 30S ribosomal protein S2 NP_072732.1 91065 D 243273 CDS NP_072733.1 12044923 875508 91924..94548 1 NC_000908.2 identified by sequence similarity; ATPase P 94548 875508 MG_071 Mycoplasma genitalium G37 ATPase P NP_072733.1 91924 D 243273 CDS NP_072734.1 12044924 875509 94535..96955 1 NC_000908.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 96955 secA 875509 secA Mycoplasma genitalium G37 preprotein translocase subunit SecA NP_072734.1 94535 D 243273 CDS NP_072735.1 12044925 875513 96933..98903 1 NC_000908.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 98903 uvrB 875513 uvrB Mycoplasma genitalium G37 excinuclease ABC subunit B NP_072735.1 96933 D 243273 CDS NP_072736.1 12044926 875254 98906..99319 1 NC_000908.2 identified by sequence similarity; hypothetical protein 99319 875254 MG_074 Mycoplasma genitalium G37 hypothetical protein NP_072736.1 98906 D 243273 CDS NP_072737.1 12044927 875465 99383..102457 1 NC_000908.2 identified by sequence similarity; hypothetical protein 102457 875465 MG_075 Mycoplasma genitalium G37 hypothetical protein NP_072737.1 99383 D 243273 CDS NP_072738.1 12044928 875486 complement(102454..102870) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 102870 875486 MG_076 Mycoplasma genitalium G37 hypothetical protein NP_072738.1 102454 R 243273 CDS NP_072739.1 12044929 875499 103104..104327 1 NC_000908.2 identified by sequence similarity; peptide ABC transporter permease 104327 oppB 875499 oppB Mycoplasma genitalium G37 peptide ABC transporter permease NP_072739.1 103104 D 243273 CDS NP_072740.1 12044930 875226 104320..105450 1 NC_000908.2 identified by sequence similarity; peptide ABC transporter permease 105450 oppC 875226 oppC Mycoplasma genitalium G37 peptide ABC transporter permease NP_072740.1 104320 D 243273 CDS NP_072741.1 12044931 875715 105452..106660 1 NC_000908.2 identified by sequence similarity; peptide ABC transporter ATP-binding protein 106660 oppD 875715 oppD Mycoplasma genitalium G37 peptide ABC transporter ATP-binding protein NP_072741.1 105452 D 243273 CDS NP_072742.1 12044932 875732 106660..109206 1 NC_000908.2 identified by sequence similarity; peptide ABC transporter ATP-binding protein 109206 oppF 875732 oppF Mycoplasma genitalium G37 peptide ABC transporter ATP-binding protein NP_072742.1 106660 D 243273 CDS NP_072743.1 12044933 875687 109262..109675 1 NC_000908.2 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 109675 rplK 875687 rplK Mycoplasma genitalium G37 50S ribosomal protein L11 NP_072743.1 109262 D 243273 CDS NP_072744.1 12044934 875701 109675..110355 1 NC_000908.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 110355 rplA 875701 rplA Mycoplasma genitalium G37 50S ribosomal protein L1 NP_072744.1 109675 D 243273 CDS NP_072745.1 12044935 875723 110355..110924 1 NC_000908.2 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 110924 pth 875723 pth Mycoplasma genitalium G37 peptidyl-tRNA hydrolase NP_072745.1 110355 D 243273 CDS NP_072746.1 12044936 875283 110917..111789 1 NC_000908.2 identified by sequence similarity; tRNA(Ile)-lysidine synthetase 111789 875283 MG_084 Mycoplasma genitalium G37 tRNA(Ile)-lysidine synthetase NP_072746.1 110917 D 243273 CDS NP_072747.1 12044937 875285 111790..112725 1 NC_000908.2 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 112725 ser 875285 ser Mycoplasma genitalium G37 HPr kinase/phosphorylase NP_072747.1 111790 D 243273 CDS NP_072748.1 12044938 875464 112718..113866 1 NC_000908.2 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 113866 lgt 875464 lgt Mycoplasma genitalium G37 prolipoprotein diacylglyceryl transferase NP_072748.1 112718 D 243273 CDS NP_072749.1 12044939 875483 113895..114314 1 NC_000908.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 114314 rpsL 875483 rpsL Mycoplasma genitalium G37 30S ribosomal protein S12 NP_072749.1 113895 D 243273 CDS NP_072750.1 12044940 875447 114331..114798 1 NC_000908.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 114798 rpS7 875447 rpS7 Mycoplasma genitalium G37 30S ribosomal protein S7 NP_072750.1 114331 D 243273 CDS NP_072751.1 12044941 875260 114808..116874 1 NC_000908.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 116874 fus 875260 fus Mycoplasma genitalium G37 elongation factor G NP_072751.1 114808 D 243273 CDS NP_072752.1 12044942 875432 116926..117552 1 NC_000908.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 117552 rpsF 875432 rpsF Mycoplasma genitalium G37 30S ribosomal protein S6 NP_072752.1 116926 D 243273 CDS NP_072753.1 12044943 875527 117553..118035 1 NC_000908.2 identified by sequence similarity; single-strand binding protein family 118035 ssb 875527 ssb Mycoplasma genitalium G37 single-strand binding protein family NP_072753.1 117553 D 243273 CDS NP_072754.1 12044944 875438 118025..118342 1 NC_000908.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 118342 rpsR 875438 rpsR Mycoplasma genitalium G37 30S ribosomal protein S18 NP_072754.1 118025 D 243273 CDS NP_072755.1 12044945 875264 118345..118797 1 NC_000908.2 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 118797 rplI 875264 rplI Mycoplasma genitalium G37 50S ribosomal protein L9 NP_072755.1 118345 D 243273 CDS NP_072756.2 108885083 875532 118781..120187 1 NC_000908.2 identified by sequence similarity; replicative DNA helicase 120187 dnaB 875532 dnaB Mycoplasma genitalium G37 replicative DNA helicase NP_072756.2 118781 D 243273 CDS NP_072757.1 12044947 875422 120191..121387 1 NC_000908.2 identified by sequence similarity; lipoprotein 121387 875422 MG_095 Mycoplasma genitalium G37 lipoprotein NP_072757.1 120191 D 243273 CDS NP_072758.1 12044948 875725 121571..123523 1 NC_000908.2 identified by sequence similarity; hypothetical protein 123523 875725 MG_096 Mycoplasma genitalium G37 hypothetical protein NP_072758.1 121571 D 243273 CDS NP_072759.1 12044949 875721 123580..124317 1 NC_000908.2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 124317 ung 875721 ung Mycoplasma genitalium G37 uracil-DNA glycosylase NP_072759.1 123580 D 243273 CDS NP_072760.1 12044950 875690 124417..125850 1 NC_000908.2 contains unknown domain at the N-terminus that is found by itself in some proteins by in others is fused to GatC at the C-terminus; aspartyl/glutamyl-tRNA amidotransferase subunit C 125850 875690 MG_098 Mycoplasma genitalium G37 aspartyl/glutamyl-tRNA amidotransferase subunit C NP_072760.1 124417 D 243273 CDS NP_072761.1 12044951 875261 125853..127286 1 NC_000908.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 127286 gatA 875261 gatA Mycoplasma genitalium G37 aspartyl/glutamyl-tRNA amidotransferase subunit A NP_072761.1 125853 D 243273 CDS NP_072762.1 12044952 875247 127279..128712 1 NC_000908.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 128712 gatB 875247 gatB Mycoplasma genitalium G37 aspartyl/glutamyl-tRNA amidotransferase subunit B NP_072762.1 127279 D 243273 CDS NP_072763.1 12044953 875406 128687..129355 1 NC_000908.2 identified by sequence similarity; hypothetical protein 129355 875406 MG_101 Mycoplasma genitalium G37 hypothetical protein NP_072763.1 128687 D 243273 CDS NP_072764.1 12044954 875416 129348..130295 1 NC_000908.2 identified by sequence similarity; thioredoxin-disulfide reductase 130295 trxB 875416 trxB Mycoplasma genitalium G37 thioredoxin-disulfide reductase NP_072764.1 129348 D 243273 CDS NP_072765.1 12044955 875251 130285..131127 1 NC_000908.2 identified by sequence similarity; hypothetical protein 131127 875251 MG_103 Mycoplasma genitalium G37 hypothetical protein NP_072765.1 130285 D 243273 CDS YP_654151.1 108885119 4126687 131149..131382 1 NC_000908.2 preprotein translocase subunit SecG 131382 secG 4126687 secG Mycoplasma genitalium G37 preprotein translocase subunit SecG YP_654151.1 131149 D 243273 CDS NP_072766.1 12044956 875442 131385..133562 1 NC_000908.2 identified by sequence similarity; ribonuclease R 133562 vacB 875442 vacB Mycoplasma genitalium G37 ribonuclease R NP_072766.1 131385 D 243273 CDS NP_072767.2 108885084 875469 133570..134172 1 NC_000908.2 identified by sequence similarity; hypothetical protein 134172 875469 MG_105 Mycoplasma genitalium G37 hypothetical protein NP_072767.2 133570 D 243273 CDS NP_072768.2 108885085 875270 complement(134147..134728) 1 NC_000908.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 134728 def 875270 def Mycoplasma genitalium G37 peptide deformylase NP_072768.2 134147 R 243273 CDS NP_072769.1 12044959 875249 134769..135338 1 NC_000908.2 identified by sequence similarity; guanylate kinase 135338 gmk 875249 gmk Mycoplasma genitalium G37 guanylate kinase NP_072769.1 134769 D 243273 CDS NP_072770.1 12044960 875507 135338..136120 1 NC_000908.2 identified by sequence similarity; protein phosphatase 2C 136120 875507 MG_108 Mycoplasma genitalium G37 protein phosphatase 2C NP_072770.1 135338 D 243273 CDS NP_072771.2 108885086 875289 136105..137268 1 NC_000908.2 identified by sequence similarity; serine/threonine protein kinase 137268 875289 MG_109 Mycoplasma genitalium G37 serine/threonine protein kinase NP_072771.2 136105 D 243273 CDS NP_072772.1 12044962 875411 137255..138091 1 NC_000908.2 identified by sequence similarity; ribosome small subunit-dependent GTPase A 138091 875411 MG_110 Mycoplasma genitalium G37 ribosome small subunit-dependent GTPase A NP_072772.1 137255 D 243273 CDS NP_072773.2 161579581 875452 138112..139407 1 NC_000908.2 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 139407 pgi 875452 pgi Mycoplasma genitalium G37 glucose-6-phosphate isomerase NP_072773.2 138112 D 243273 CDS NP_072774.1 12044964 875550 139397..140026 1 NC_000908.2 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 140026 875550 MG_112 Mycoplasma genitalium G37 ribulose-phosphate 3-epimerase NP_072774.1 139397 D 243273 CDS NP_072775.1 12044965 875695 140040..141410 1 NC_000908.2 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 141410 asnC 875695 asnC Mycoplasma genitalium G37 asparaginyl-tRNA synthetase NP_072775.1 140040 D 243273 CDS NP_072776.1 12044966 875551 141346..142056 1 NC_000908.2 identified by sequence similarity; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 142056 pgsA 875551 pgsA Mycoplasma genitalium G37 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP_072776.1 141346 D 243273 CDS NP_072777.1 12044967 875498 142081..142554 1 NC_000908.2 identified by sequence similarity; competence/damage inducible protein CinA 142554 875498 MG_115 Mycoplasma genitalium G37 competence/damage inducible protein CinA NP_072777.1 142081 D 243273 CDS NP_072778.1 12044968 875546 142563..143318 1 NC_000908.2 identified by sequence similarity; hypothetical protein 143318 875546 MG_116 Mycoplasma genitalium G37 hypothetical protein NP_072778.1 142563 D 243273 CDS NP_072779.1 12044969 875547 143311..143955 1 NC_000908.2 identified by sequence similarity; hypothetical protein 143955 875547 MG_117 Mycoplasma genitalium G37 hypothetical protein NP_072779.1 143311 D 243273 CDS NP_072780.1 12044970 875535 143936..144958 1 NC_000908.2 identified by sequence similarity; UDP-glucose 4-epimerase 144958 galE 875535 galE Mycoplasma genitalium G37 UDP-glucose 4-epimerase NP_072780.1 143936 D 243273 CDS NP_072781.1 12044971 875548 144973..146667 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein 146667 mglA 875548 mglA Mycoplasma genitalium G37 ABC transporter ATP-binding protein NP_072781.1 144973 D 243273 CDS NP_072782.1 12044972 875541 146674..148236 1 NC_000908.2 identified by sequence similarity; ABC transporter permease 148236 875541 MG_120 Mycoplasma genitalium G37 ABC transporter permease NP_072782.1 146674 D 243273 CDS NP_072783.1 12044973 875709 148239..149159 1 NC_000908.2 identified by sequence similarity; ABC transporter permease 149159 875709 MG_121 Mycoplasma genitalium G37 ABC transporter permease NP_072783.1 148239 D 243273 CDS NP_072784.1 12044974 875227 149199..151328 1 NC_000908.2 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 151328 topA 875227 topA Mycoplasma genitalium G37 DNA topoisomerase I NP_072784.1 149199 D 243273 CDS NP_072785.1 12044975 875408 151306..152721 1 NC_000908.2 identified by sequence similarity; hypothetical protein 152721 875408 MG_123 Mycoplasma genitalium G37 hypothetical protein NP_072785.1 151306 D 243273 CDS NP_072786.1 12044976 875225 152768..153076 1 NC_000908.2 identified by sequence similarity; thioredoxin 153076 trxA 875225 trxA Mycoplasma genitalium G37 thioredoxin NP_072786.1 152768 D 243273 CDS NP_072787.1 12044977 875402 153082..153939 1 NC_000908.2 identified by sequence similarity; Cof-like hydrolase 153939 875402 MG_125 Mycoplasma genitalium G37 Cof-like hydrolase NP_072787.1 153082 D 243273 CDS NP_072788.1 12044978 875379 complement(153920..154963) 1 NC_000908.2 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 154963 trpS 875379 trpS Mycoplasma genitalium G37 tryptophanyl-tRNA synthetase NP_072788.1 153920 R 243273 CDS NP_072789.1 12044979 875375 154999..155436 1 NC_000908.2 identified by sequence similarity; Spx subfamily protein 155436 875375 MG_127 Mycoplasma genitalium G37 Spx subfamily protein NP_072789.1 154999 D 243273 CDS NP_072790.1 12044980 875342 155444..156223 1 NC_000908.2 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 156223 ppnK 875342 ppnK Mycoplasma genitalium G37 inorganic polyphosphate/ATP-NAD kinase NP_072790.1 155444 D 243273 CDS NP_072791.1 12044981 875287 156223..156576 1 NC_000908.2 identified by sequence similarity; hypothetical protein 156576 875287 MG_129 Mycoplasma genitalium G37 hypothetical protein NP_072791.1 156223 D 243273 CDS NP_072792.1 12044982 875274 156566..158020 1 NC_000908.2 identified by sequence similarity; hypothetical protein 158020 875274 MG_130 Mycoplasma genitalium G37 hypothetical protein NP_072792.1 156566 D 243273 CDS NP_072794.1 12044984 875581 complement(158581..159006) 1 NC_000908.2 identified by sequence similarity; HIT domain-containing protein 159006 875581 MG_132 Mycoplasma genitalium G37 HIT domain-containing protein NP_072794.1 158581 R 243273 CDS NP_072795.2 108885087 875277 complement(158984..159778) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 159778 875277 MG_133 Mycoplasma genitalium G37 hypothetical protein NP_072795.2 158984 R 243273 CDS NP_072796.1 12044986 875231 159798..160100 1 NC_000908.2 identified by sequence similarity; hypothetical protein 160100 875231 MG_134 Mycoplasma genitalium G37 hypothetical protein NP_072796.1 159798 D 243273 CDS NP_072797.1 12044987 875722 complement(160072..160914) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 160914 875722 MG_135 Mycoplasma genitalium G37 hypothetical protein NP_072797.1 160072 R 243273 CDS NP_072798.1 12044988 875448 160963..162435 1 NC_000908.2 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 162435 lysS 875448 lysS Mycoplasma genitalium G37 lysyl-tRNA synthetase NP_072798.1 160963 D 243273 CDS NP_072799.1 12044989 875453 162377..163591 1 NC_000908.2 identified by sequence similarity; UDP-galactopyranose mutase 163591 glf 875453 glf Mycoplasma genitalium G37 UDP-galactopyranose mutase NP_072799.1 162377 D 243273 CDS NP_072800.1 12044990 875539 163591..165387 1 NC_000908.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 165387 lepA 875539 lepA Mycoplasma genitalium G37 GTP-binding protein LepA NP_072800.1 163591 D 243273 CDS NP_072801.1 12044991 875237 165471..167180 1 NC_000908.2 identified by sequence similarity; metallo-beta-lactamase superfamily protein 167180 875237 MG_139 Mycoplasma genitalium G37 metallo-beta-lactamase superfamily protein NP_072801.1 165471 D 243273 CDS NP_072802.1 12044992 875533 175805..179146 1 NC_000908.2 identified by sequence similarity; hypothetical protein 179146 875533 MG_140 Mycoplasma genitalium G37 hypothetical protein NP_072802.1 175805 D 243273 CDS NP_072803.1 12044993 875500 179151..180746 1 NC_000908.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 180746 nusA 875500 nusA Mycoplasma genitalium G37 transcription elongation factor NusA NP_072803.1 179151 D 243273 CDS YP_654152.1 108885120 4126688 180746..181018 1 NC_000908.2 hypothetical protein 181018 4126688 MG_477 Mycoplasma genitalium G37 hypothetical protein YP_654152.1 180746 D 243273 CDS NP_072804.1 12044994 875480 181005..182864 1 NC_000908.2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 182864 infB 875480 infB Mycoplasma genitalium G37 translation initiation factor IF-2 NP_072804.1 181005 D 243273 CDS NP_072805.1 12044995 875468 182851..183189 1 NC_000908.2 identified by sequence similarity; ribosome-binding factor A 183189 875468 MG_143 Mycoplasma genitalium G37 ribosome-binding factor A NP_072805.1 182851 D 243273 CDS NP_072806.1 12044996 875217 183214..184053 1 NC_000908.2 identified by sequence similarity; hypothetical protein 184053 875217 MG_144 Mycoplasma genitalium G37 hypothetical protein NP_072806.1 183214 D 243273 CDS NP_072807.1 12044997 875524 184053..184862 1 NC_000908.2 identified by sequence similarity; riboflavin biosynthesis protein RibF 184862 875524 MG_145 Mycoplasma genitalium G37 riboflavin biosynthesis protein RibF NP_072807.1 184053 D 243273 CDS NP_072808.1 12044998 875520 184875..186149 1 NC_000908.2 identified by sequence similarity; hypothetical protein 186149 875520 MG_146 Mycoplasma genitalium G37 hypothetical protein NP_072808.1 184875 D 243273 CDS NP_072809.2 108885088 875472 186136..187263 1 NC_000908.2 identified by sequence similarity; hypothetical protein 187263 875472 MG_147 Mycoplasma genitalium G37 hypothetical protein NP_072809.2 186136 D 243273 CDS NP_072810.1 12045000 875475 187302..188531 1 NC_000908.2 identified by sequence similarity; hypothetical protein 188531 875475 MG_148 Mycoplasma genitalium G37 hypothetical protein NP_072810.1 187302 D 243273 CDS NP_072811.1 12045001 875240 188607..189452 1 NC_000908.2 identified by sequence similarity; lipoprotein 189452 875240 MG_149 Mycoplasma genitalium G37 lipoprotein NP_072811.1 188607 D 243273 CDS NP_072812.2 108885089 875467 189492..189956 1 NC_000908.2 identified by sequence similarity; hypothetical protein 189956 875467 MG_478 Mycoplasma genitalium G37 hypothetical protein NP_072812.2 189492 D 243273 CDS NP_072813.1 12045003 875470 190046..190366 1 NC_000908.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 190366 rpsJ 875470 rpsJ Mycoplasma genitalium G37 30S ribosomal protein S10 NP_072813.1 190046 D 243273 CDS NP_072814.1 12045004 875552 190370..191143 1 NC_000908.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 191143 rplC 875552 rplC Mycoplasma genitalium G37 50S ribosomal protein L3 NP_072814.1 190370 D 243273 CDS NP_072815.1 12045005 875518 191143..191778 1 NC_000908.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 191778 rplD 875518 rplD Mycoplasma genitalium G37 50S ribosomal protein L4 NP_072815.1 191143 D 243273 CDS NP_072816.1 12045006 875471 191782..192102 1 NC_000908.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 192102 rplW 875471 rplW Mycoplasma genitalium G37 50S ribosomal protein L23 NP_072816.1 191782 D 243273 CDS NP_072817.1 12045007 875534 192102..192959 1 NC_000908.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 192959 rplB 875534 rplB Mycoplasma genitalium G37 50S ribosomal protein L2 NP_072817.1 192102 D 243273 CDS NP_072818.1 12045008 875544 192959..193222 1 NC_000908.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 193222 rpsS 875544 rpsS Mycoplasma genitalium G37 30S ribosomal protein S19 NP_072818.1 192959 D 243273 CDS NP_072819.1 12045009 875460 193225..193659 1 NC_000908.2 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 193659 rplV 875460 rplV Mycoplasma genitalium G37 50S ribosomal protein L22 NP_072819.1 193225 D 243273 CDS NP_072820.1 12045010 875444 193662..194468 1 NC_000908.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 194468 rpsC 875444 rpsC Mycoplasma genitalium G37 30S ribosomal protein S3 NP_072820.1 193662 D 243273 CDS NP_072821.1 12045011 875503 194474..194890 1 NC_000908.2 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 194890 rplP 875503 rplP Mycoplasma genitalium G37 50S ribosomal protein L16 NP_072821.1 194474 D 243273 CDS NP_072822.1 12045012 875418 194890..195492 1 NC_000908.2 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 195492 rpmC 875418 rpmC Mycoplasma genitalium G37 50S ribosomal protein L29 NP_072822.1 194890 D 243273 CDS NP_072823.1 12045013 875275 195492..195749 1 NC_000908.2 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 195749 rpsQ 875275 rpsQ Mycoplasma genitalium G37 30S ribosomal protein S17 NP_072823.1 195492 D 243273 CDS NP_072824.1 12045014 875685 195753..196121 1 NC_000908.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 196121 rplN 875685 rplN Mycoplasma genitalium G37 50S ribosomal protein L14 NP_072824.1 195753 D 243273 CDS NP_072825.1 12045015 875711 196121..196447 1 NC_000908.2 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 196447 rplX 875711 rplX Mycoplasma genitalium G37 50S ribosomal protein L24 NP_072825.1 196121 D 243273 CDS NP_072826.1 12045016 875230 196453..196995 1 NC_000908.2 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 196995 rplE 875230 rplE Mycoplasma genitalium G37 50S ribosomal protein L5 NP_072826.1 196453 D 243273 CDS NP_072827.1 12045017 875554 196998..197183 1 NC_000908.2 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 197183 rpsN 875554 rpsN Mycoplasma genitalium G37 30S ribosomal protein S14 NP_072827.1 196998 D 243273 CDS NP_072828.1 12045018 875692 197177..197602 1 NC_000908.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 197602 rpsH 875692 rpsH Mycoplasma genitalium G37 30S ribosomal protein S8 NP_072828.1 197177 D 243273 CDS NP_072829.1 12045019 875542 197609..198163 1 NC_000908.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 198163 rplF 875542 rplF Mycoplasma genitalium G37 50S ribosomal protein L6 NP_072829.1 197609 D 243273 CDS NP_072830.1 12045020 875718 198165..198512 1 NC_000908.2 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 198512 rplR 875718 rplR Mycoplasma genitalium G37 50S ribosomal protein L18 NP_072830.1 198165 D 243273 CDS NP_072831.1 12045021 875256 198517..199152 1 NC_000908.2 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 199152 rpsE 875256 rpsE Mycoplasma genitalium G37 30S ribosomal protein S5 NP_072831.1 198517 D 243273 CDS NP_072832.1 12045022 875570 199158..199610 1 NC_000908.2 late assembly protein; 50S ribosomal protein L15 199610 rplO 875570 rplO Mycoplasma genitalium G37 50S ribosomal protein L15 NP_072832.1 199158 D 243273 CDS NP_072833.1 12045023 875393 199610..201037 1 NC_000908.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 201037 secY 875393 secY Mycoplasma genitalium G37 preprotein translocase subunit SecY NP_072833.1 199610 D 243273 CDS NP_072834.1 12045024 875540 201031..201675 1 NC_000908.2 identified by sequence similarity; adenylate kinase 201675 adk 875540 adk Mycoplasma genitalium G37 adenylate kinase NP_072834.1 201031 D 243273 CDS NP_072835.1 12045025 875255 201678..202424 1 NC_000908.2 identified by sequence similarity; methionine aminopeptidase, type I 202424 map 875255 map Mycoplasma genitalium G37 methionine aminopeptidase, type I NP_072835.1 201678 D 243273 CDS NP_072836.1 12045026 875265 202424..202636 1 NC_000908.2 identified by sequence similarity; translation initiation factor IF-1 202636 infA 875265 infA Mycoplasma genitalium G37 translation initiation factor IF-1 NP_072836.1 202424 D 243273 CDS NP_072837.1 12045027 875341 202647..202760 1 NC_000908.2 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 202760 rpmJ 875341 rpmJ Mycoplasma genitalium G37 50S ribosomal protein L36 NP_072837.1 202647 D 243273 CDS NP_072838.1 12045028 875378 202760..203134 1 NC_000908.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 203134 rpsM 875378 rpsM Mycoplasma genitalium G37 30S ribosomal protein S13 NP_072838.1 202760 D 243273 CDS NP_072839.2 108885090 875401 203134..203499 1 NC_000908.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 203499 rpS11 875401 rpS11 Mycoplasma genitalium G37 30S ribosomal protein S11 NP_072839.2 203134 D 243273 CDS NP_072840.1 12045030 875383 203515..204501 1 NC_000908.2 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 204501 rpoA 875383 rpoA Mycoplasma genitalium G37 DNA-directed RNA polymerase subunit alpha NP_072840.1 203515 D 243273 CDS NP_072841.1 12045031 875431 204514..204885 1 NC_000908.2 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 204885 rplQ 875431 rplQ Mycoplasma genitalium G37 50S ribosomal protein L17 NP_072841.1 204514 D 243273 CDS NP_072842.1 12045032 875266 204872..205696 1 NC_000908.2 with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 205696 cbiO 875266 cbiO Mycoplasma genitalium G37 cobalt transporter ATP-binding subunit NP_072842.1 204872 D 243273 CDS NP_072843.1 12045033 875238 205681..206595 1 NC_000908.2 with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 206595 cbiO 875238 cbiO Mycoplasma genitalium G37 cobalt transporter ATP-binding subunit NP_072843.1 205681 D 243273 CDS NP_072844.1 12045034 875530 206588..207850 1 NC_000908.2 identified by sequence similarity; metal ABC transporter permease 207850 875530 MG_181 Mycoplasma genitalium G37 metal ABC transporter permease NP_072844.1 206588 D 243273 CDS NP_072845.1 12045035 875727 207843..208577 1 NC_000908.2 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 208577 truA 875727 truA Mycoplasma genitalium G37 tRNA pseudouridine synthase A NP_072845.1 207843 D 243273 CDS NP_072846.1 12045036 875531 208567..210390 1 NC_000908.2 identified by sequence similarity; oligoendopeptidase F 210390 pepF 875531 pepF Mycoplasma genitalium G37 oligoendopeptidase F NP_072846.1 208567 D 243273 CDS NP_072847.1 12045037 875719 210391..211344 1 NC_000908.2 identified by sequence similarity; adenine-specific DNA modification methylase 211344 875719 MG_184 Mycoplasma genitalium G37 adenine-specific DNA modification methylase NP_072847.1 210391 D 243273 CDS NP_072848.1 12045038 875234 211444..213549 1 NC_000908.2 identified by sequence similarity; lipoprotein 213549 875234 MG_185 Mycoplasma genitalium G37 lipoprotein NP_072848.1 211444 D 243273 CDS NP_072849.1 12045039 875720 216016..216768 1 NC_000908.2 identified by sequence similarity; nuclease-like protein 216768 875720 MG_186 Mycoplasma genitalium G37 nuclease-like protein NP_072849.1 216016 D 243273 CDS NP_072850.1 12045040 875286 216761..218518 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein 218518 875286 MG_187 Mycoplasma genitalium G37 ABC transporter ATP-binding protein NP_072850.1 216761 D 243273 CDS NP_072851.1 12045041 875538 218521..219510 1 NC_000908.2 identified by sequence similarity; ABC transporter permease 219510 875538 MG_188 Mycoplasma genitalium G37 ABC transporter permease NP_072851.1 218521 D 243273 CDS NP_072852.2 108885091 875233 219482..220438 1 NC_000908.2 identified by sequence similarity; ABC transporter permease 220438 875233 MG_189 Mycoplasma genitalium G37 ABC transporter permease NP_072852.2 219482 D 243273 CDS NP_072853.2 108885092 875410 220607..221563 1 NC_000908.2 identified by sequence similarity; DHH family phosphoesterase 221563 mgpA 875410 mgpA Mycoplasma genitalium G37 DHH family phosphoesterase NP_072853.2 220607 D 243273 CDS NP_072854.1 12045044 875543 221570..225904 1 NC_000908.2 identified by sequence similarity; MgPa adhesin 225904 mgpB 875543 mgpB Mycoplasma genitalium G37 MgPa adhesin NP_072854.1 221570 D 243273 CDS NP_072855.2 108885093 875288 225906..229067 1 NC_000908.2 identified by sequence similarity; hypothetical protein 229067 mgpC 875288 mgpC Mycoplasma genitalium G37 hypothetical protein NP_072855.2 225906 D 243273 CDS NP_072856.1 12045046 875437 232009..233034 1 NC_000908.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 233034 pheS 875437 pheS Mycoplasma genitalium G37 phenylalanyl-tRNA synthetase subunit alpha NP_072856.1 232009 D 243273 CDS NP_072857.1 12045047 875729 233038..235458 1 NC_000908.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 235458 pheT 875729 pheT Mycoplasma genitalium G37 phenylalanyl-tRNA synthetase subunit beta NP_072857.1 233038 D 243273 CDS NP_072858.1 12045048 875698 235517..236062 1 NC_000908.2 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 236062 infC 875698 infC Mycoplasma genitalium G37 translation initiation factor IF-3 NP_072858.1 235517 D 243273 CDS NP_072859.1 12045049 875484 236065..236244 1 NC_000908.2 identified by sequence similarity; 50S ribosomal protein L35 236244 rpmI 875484 rpmI Mycoplasma genitalium G37 50S ribosomal protein L35 NP_072859.1 236065 D 243273 CDS NP_072860.1 12045050 875430 236247..236621 1 NC_000908.2 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 236621 rplT 875430 rplT Mycoplasma genitalium G37 50S ribosomal protein L20 NP_072860.1 236247 D 243273 CDS NP_072862.1 12045052 875694 237347..239152 1 NC_000908.2 identified by sequence similarity; DnaJ domain-containing protein 239152 875694 MG_200 Mycoplasma genitalium G37 DnaJ domain-containing protein NP_072862.1 237347 D 243273 CDS NP_072863.1 12045053 875689 239164..239817 1 NC_000908.2 identified by sequence similarity; co-chaperone GrpE 239817 grpE 875689 grpE Mycoplasma genitalium G37 co-chaperone GrpE NP_072863.1 239164 D 243273 CDS NP_072864.1 12045054 875691 239827..240195 1 NC_000908.2 identified by sequence similarity; hypothetical protein 240195 875691 MG_202 Mycoplasma genitalium G37 hypothetical protein NP_072864.1 239827 D 243273 CDS NP_072865.1 12045055 875693 240323..242224 1 NC_000908.2 identified by sequence similarity; DNA topoisomerase IV, B subunit 242224 parE 875693 parE Mycoplasma genitalium G37 DNA topoisomerase IV, B subunit NP_072865.1 240323 D 243273 CDS NP_072866.1 12045056 875340 242224..244569 1 NC_000908.2 identified by sequence similarity; DNA topoisomerase IV, A subunit 244569 parC 875340 parC Mycoplasma genitalium G37 DNA topoisomerase IV, A subunit NP_072866.1 242224 D 243273 CDS NP_072867.1 12045057 875407 complement(244566..245597) 1 NC_000908.2 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 245597 hrcA 875407 hrcA Mycoplasma genitalium G37 heat-inducible transcription repressor NP_072867.1 244566 R 243273 CDS NP_072868.1 12045058 875724 245633..247426 1 NC_000908.2 identified by sequence similarity; excinuclease ABC, C subunit 247426 uvrC 875724 uvrC Mycoplasma genitalium G37 excinuclease ABC, C subunit NP_072868.1 245633 D 243273 CDS NP_072869.1 12045059 875395 247407..247910 1 NC_000908.2 identified by sequence similarity; serine/threonine protein phosphatase 247910 875395 MG_207 Mycoplasma genitalium G37 serine/threonine protein phosphatase NP_072869.1 247407 D 243273 CDS NP_072870.1 12045060 875397 complement(247903..248493) 1 NC_000908.2 identified by sequence similarity; glycoprotease 248493 875397 MG_208 Mycoplasma genitalium G37 glycoprotease NP_072870.1 247903 R 243273 CDS NP_072871.1 12045061 875377 complement(248477..249403) 1 NC_000908.2 identified by sequence similarity; RluA family pseudouridine synthase 249403 875377 MG_209 Mycoplasma genitalium G37 RluA family pseudouridine synthase NP_072871.1 248477 R 243273 CDS NP_072872.1 12045062 875392 complement(249403..249948) 1 NC_000908.2 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; signal peptidase II 249948 lspA 875392 lspA Mycoplasma genitalium G37 signal peptidase II NP_072872.1 249403 R 243273 CDS NP_072873.1 12045063 875712 250149..250808 1 NC_000908.2 identified by sequence similarity; hypothetical protein 250808 875712 MG_480 Mycoplasma genitalium G37 hypothetical protein NP_072873.1 250149 D 243273 CDS NP_072874.1 12045331 875583 250808..250996 1 NC_000908.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 250996 rpsU 875583 rpsU Mycoplasma genitalium G37 30S ribosomal protein S21 NP_072874.1 250808 D 243273 CDS NP_072875.1 12045064 875335 250998..251441 1 NC_000908.2 identified by sequence similarity; hypothetical protein 251441 875335 MG_211 Mycoplasma genitalium G37 hypothetical protein NP_072875.1 250998 D 243273 CDS NP_072876.1 12045065 875324 251444..251788 1 NC_000908.2 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 251788 acpS 875324 acpS Mycoplasma genitalium G37 4'-phosphopantetheinyl transferase NP_072876.1 251444 D 243273 CDS NP_072877.1 12045066 875333 251781..252587 1 NC_000908.2 identified by sequence similarity; 1-acyl-sn-glycerol-3-phosphate acyltransferase 252587 plsC 875333 plsC Mycoplasma genitalium G37 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_072877.1 251781 D 243273 CDS NP_072878.1 12045067 875334 252580..253995 1 NC_000908.2 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 253995 scpA 875334 scpA Mycoplasma genitalium G37 segregation and condensation protein A NP_072878.1 252580 D 243273 CDS NP_072879.1 12045068 875337 253979..254602 1 NC_000908.2 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 254602 scpB 875337 scpB Mycoplasma genitalium G37 segregation and condensation protein B NP_072879.1 253979 D 243273 CDS NP_072880.1 12045069 875293 254621..255592 1 NC_000908.2 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 255592 pfkA 875293 pfkA Mycoplasma genitalium G37 6-phosphofructokinase NP_072880.1 254621 D 243273 CDS NP_072881.1 12045070 875390 255595..257121 1 NC_000908.2 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 257121 pyk 875390 pyk Mycoplasma genitalium G37 pyruvate kinase NP_072881.1 255595 D 243273 CDS NP_072882.1 12045071 875361 258041..259159 1 NC_000908.2 identified by sequence similarity; proline-rich P65 protein 259159 875361 MG_217 Mycoplasma genitalium G37 proline-rich P65 protein NP_072882.1 258041 D 243273 CDS NP_072883.1 12045072 875360 259177..264594 1 NC_000908.2 identified by sequence similarity; HMW2 cytadherence accessory protein 264594 hmw2 875360 hmw2 Mycoplasma genitalium G37 HMW2 cytadherence accessory protein NP_072883.1 259177 D 243273 CDS NP_072884.1 12045073 875359 264597..265637 1 NC_000908.2 identified by sequence similarity; hypothetical protein 265637 875359 MG_491 Mycoplasma genitalium G37 hypothetical protein NP_072884.1 264597 D 243273 CDS NP_072885.1 12045074 875358 265597..266043 1 NC_000908.2 hypothetical protein; identified by GeneMark; hypothetical protein 266043 875358 MG_219 Mycoplasma genitalium G37 hypothetical protein NP_072885.1 265597 D 243273 CDS NP_072886.2 108885094 875357 complement(266075..266356) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 266356 875357 MG_220 Mycoplasma genitalium G37 hypothetical protein NP_072886.2 266075 R 243273 CDS NP_072887.2 108885095 875318 266666..267091 1 NC_000908.2 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 267091 875318 MG_221 Mycoplasma genitalium G37 cell division protein MraZ NP_072887.2 266666 D 243273 CDS NP_072888.1 12045077 875317 267081..268010 1 NC_000908.2 identified by sequence similarity; S-adenosyl-methyltransferase MraW 268010 mraW 875317 mraW Mycoplasma genitalium G37 S-adenosyl-methyltransferase MraW NP_072888.1 267081 D 243273 CDS NP_072889.1 12045078 875316 268012..269247 1 NC_000908.2 identified by sequence similarity; hypothetical protein 269247 875316 MG_223 Mycoplasma genitalium G37 hypothetical protein NP_072889.1 268012 D 243273 CDS NP_072890.1 12045079 875315 269250..270359 1 NC_000908.2 identified by sequence similarity; cell division protein FtsZ 270359 ftsZ 875315 ftsZ Mycoplasma genitalium G37 cell division protein FtsZ NP_072890.1 269250 D 243273 CDS NP_072891.1 12045080 875314 270405..271874 1 NC_000908.2 identified by sequence similarity; amino acid-polyamine-organocation (APC) permease family protein 271874 875314 MG_225 Mycoplasma genitalium G37 amino acid-polyamine-organocation (APC) permease family protein NP_072891.1 270405 D 243273 CDS NP_072892.2 108885096 875313 271840..273318 1 NC_000908.2 identified by sequence similarity; amino acid-polyamine-organocation (APC) permease family protein 273318 875313 MG_226 Mycoplasma genitalium G37 amino acid-polyamine-organocation (APC) permease family protein NP_072892.2 271840 D 243273 CDS NP_072893.1 12045082 875312 273790..274653 1 NC_000908.2 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 274653 thyA 875312 thyA Mycoplasma genitalium G37 thymidylate synthase NP_072893.1 273790 D 243273 CDS NP_072894.1 12045083 875311 274653..275135 1 NC_000908.2 identified by sequence similarity; dihydrofolate reductase 275135 dhfR 875311 dhfR Mycoplasma genitalium G37 dihydrofolate reductase NP_072894.1 274653 D 243273 CDS NP_072895.1 12045084 875310 275141..276163 1 NC_000908.2 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 276163 nrdF 875310 nrdF Mycoplasma genitalium G37 ribonucleotide-diphosphate reductase subunit beta NP_072895.1 275141 D 243273 CDS NP_072896.1 12045085 875309 276167..276628 1 NC_000908.2 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 276628 nrdI 875309 nrdI Mycoplasma genitalium G37 ribonucleotide reductase stimulatory protein NP_072896.1 276167 D 243273 CDS NP_072897.1 12045086 875308 276647..278812 1 NC_000908.2 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 278812 nrdE 875308 nrdE Mycoplasma genitalium G37 ribonucleotide-diphosphate reductase subunit alpha NP_072897.1 276647 D 243273 CDS NP_072898.1 12045087 875299 278905..279207 1 NC_000908.2 identified by sequence similarity; 50S ribosomal protein L21 279207 rplU 875299 rplU Mycoplasma genitalium G37 50S ribosomal protein L21 NP_072898.1 278905 D 243273 CDS NP_072899.1 12045088 875298 279200..279499 1 NC_000908.2 identified by sequence similarity; hypothetical protein 279499 875298 MG_233 Mycoplasma genitalium G37 hypothetical protein NP_072899.1 279200 D 243273 CDS NP_072900.1 12045089 875297 279492..279806 1 NC_000908.2 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 279806 rpmA 875297 rpmA Mycoplasma genitalium G37 50S ribosomal protein L27 NP_072900.1 279492 D 243273 CDS NP_072901.1 12045090 875296 279799..280674 1 NC_000908.2 identified by sequence similarity; apurinic endonuclease (APN1) 280674 875296 MG_235 Mycoplasma genitalium G37 apurinic endonuclease (APN1) NP_072901.1 279799 D 243273 CDS NP_072902.1 12045091 875374 280664..281086 1 NC_000908.2 identified by sequence similarity; hypothetical protein 281086 875374 MG_236 Mycoplasma genitalium G37 hypothetical protein NP_072902.1 280664 D 243273 CDS NP_072903.1 12045092 875373 281079..281963 1 NC_000908.2 identified by sequence similarity; hypothetical protein 281963 875373 MG_237 Mycoplasma genitalium G37 hypothetical protein NP_072903.1 281079 D 243273 CDS NP_072904.1 12045093 875304 281993..283327 1 NC_000908.2 identified by sequence similarity; trigger factor 283327 tig 875304 tig Mycoplasma genitalium G37 trigger factor NP_072904.1 281993 D 243273 CDS NP_072905.1 12045094 875303 283396..285783 1 NC_000908.2 identified by sequence similarity; ATP-dependent protease La 285783 lon 875303 lon Mycoplasma genitalium G37 ATP-dependent protease La NP_072905.1 283396 D 243273 CDS NP_072906.2 108885097 875302 complement(285780..286832) 1 NC_000908.2 catalyzes the reversible adenylation of nicotinate mononucleotide to nicotinic acid adenine dinucleotide; nicotinate-nucleotide adenylyltransferase 286832 nadD 875302 nadD Mycoplasma genitalium G37 nicotinate-nucleotide adenylyltransferase NP_072906.2 285780 R 243273 CDS NP_072907.1 12045096 875301 286885..288747 1 NC_000908.2 identified by sequence similarity; hypothetical protein 288747 875301 MG_241 Mycoplasma genitalium G37 hypothetical protein NP_072907.1 286885 D 243273 CDS NP_072908.1 12045097 875372 288753..290645 1 NC_000908.2 identified by sequence similarity; hypothetical protein 290645 875372 MG_242 Mycoplasma genitalium G37 hypothetical protein NP_072908.1 288753 D 243273 CDS NP_072909.1 12045098 875370 291334..293445 1 NC_000908.2 identified by sequence similarity; UvrD/REP helicase 293445 875370 MG_244 Mycoplasma genitalium G37 UvrD/REP helicase NP_072909.1 291334 D 243273 CDS NP_072910.1 12045099 875369 293448..293945 1 NC_000908.2 identified by sequence similarity; 5-formyltetrahydrofolate cyclo-ligase 293945 875369 MG_245 Mycoplasma genitalium G37 5-formyltetrahydrofolate cyclo-ligase NP_072910.1 293448 D 243273 CDS NP_072911.1 12045100 875368 293938..294783 1 NC_000908.2 identified by sequence similarity; serine/threonine protein phosphatase 294783 875368 MG_246 Mycoplasma genitalium G37 serine/threonine protein phosphatase NP_072911.1 293938 D 243273 CDS NP_072912.1 12045101 875367 complement(294767..295486) 1 NC_000908.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 295486 875367 MG_247 Mycoplasma genitalium G37 glycerol-3-phosphate acyltransferase PlsY NP_072912.1 294767 R 243273 CDS NP_072913.1 12045102 875322 complement(295473..296129) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 296129 875322 MG_248 Mycoplasma genitalium G37 hypothetical protein NP_072913.1 295473 R 243273 CDS NP_072914.1 12045103 875321 complement(296113..297606) 1 NC_000908.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 297606 rpoD 875321 rpoD Mycoplasma genitalium G37 RNA polymerase sigma factor NP_072914.1 296113 R 243273 CDS NP_072915.1 12045104 875320 complement(297651..299474) 1 NC_000908.2 identified by sequence similarity; DNA primase 299474 dnaE 875320 dnaE Mycoplasma genitalium G37 DNA primase NP_072915.1 297651 R 243273 CDS NP_072916.1 12045105 875319 complement(299464..300804) 1 NC_000908.2 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 300804 875319 MG_251 Mycoplasma genitalium G37 glycyl-tRNA synthetase NP_072916.1 299464 R 243273 CDS NP_072917.1 12045106 875332 complement(300824..301552) 1 NC_000908.2 identified by sequence similarity; RNA methyltransferase 301552 875332 MG_252 Mycoplasma genitalium G37 RNA methyltransferase NP_072917.1 300824 R 243273 CDS NP_072918.1 12045107 875331 complement(301555..302841) 1 NC_000908.2 identified by sequence similarity; cysteinyl-tRNA synthetase 302841 cysS 875331 cysS Mycoplasma genitalium G37 cysteinyl-tRNA synthetase NP_072918.1 301555 R 243273 CDS NP_072919.1 12045108 875330 complement(302846..304825) 1 NC_000908.2 identified by sequence similarity; DNA ligase, NAD-dependent 304825 875330 MG_254 Mycoplasma genitalium G37 DNA ligase, NAD-dependent NP_072919.1 302846 R 243273 CDS NP_072920.1 12045109 875328 305001..306098 1 NC_000908.2 identified by sequence similarity; hypothetical protein 306098 875328 MG_255 Mycoplasma genitalium G37 hypothetical protein NP_072920.1 305001 D 243273 CDS NP_072922.1 12045111 875353 306821..307591 1 NC_000908.2 identified by sequence similarity; hypothetical protein 307591 875353 MG_256 Mycoplasma genitalium G37 hypothetical protein NP_072922.1 306821 D 243273 CDS NP_072923.1 12045112 875352 307637..307930 1 NC_000908.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 307930 rpmE 875352 rpmE Mycoplasma genitalium G37 50S ribosomal protein L31 NP_072923.1 307637 D 243273 CDS NP_072924.1 12045113 875351 307930..309009 1 NC_000908.2 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 309009 prfA 875351 prfA Mycoplasma genitalium G37 peptide chain release factor 1 NP_072924.1 307930 D 243273 CDS NP_072925.1 12045114 875350 309010..310380 1 NC_000908.2 identified by sequence similarity; HemK family modification methylase 310380 875350 MG_259 Mycoplasma genitalium G37 HemK family modification methylase NP_072925.1 309010 D 243273 CDS NP_072926.1 12045115 875349 310511..312808 1 NC_000908.2 identified by sequence similarity; lipoprotein 312808 875349 MG_260 Mycoplasma genitalium G37 lipoprotein NP_072926.1 310511 D 243273 CDS NP_072927.1 12045116 875381 315701..318325 1 NC_000908.2 identified by sequence similarity; DNA polymerase III subunit alpha 318325 polC-2 875381 polC-2 Mycoplasma genitalium G37 DNA polymerase III subunit alpha NP_072927.1 315701 D 243273 CDS NP_072928.1 12045117 875380 318332..319207 1 NC_000908.2 identified by sequence similarity; 5'-3' exonuclease 319207 875380 MG_262 Mycoplasma genitalium G37 5'-3' exonuclease NP_072928.1 318332 D 243273 CDS NP_072929.1 12045118 875325 319207..320061 1 NC_000908.2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 320061 mutM 875325 mutM Mycoplasma genitalium G37 formamidopyrimidine-DNA glycosylase NP_072929.1 319207 D 243273 CDS NP_072930.1 12045119 875307 320177..321052 1 NC_000908.2 identified by sequence similarity; Cof-like hydrolase 321052 875307 MG_263 Mycoplasma genitalium G37 Cof-like hydrolase NP_072930.1 320177 D 243273 CDS NP_072931.1 12045120 875306 321046..321642 1 NC_000908.2 identified by sequence similarity; dephospho-CoA kinase 321642 875306 MG_264 Mycoplasma genitalium G37 dephospho-CoA kinase NP_072931.1 321046 D 243273 CDS NP_072932.1 12045121 875305 complement(321578..322414) 1 NC_000908.2 identified by sequence similarity; Cof-like hydrolase 322414 875305 MG_265 Mycoplasma genitalium G37 Cof-like hydrolase NP_072932.1 321578 R 243273 CDS NP_072933.1 12045122 875347 complement(322433..324811) 1 NC_000908.2 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 324811 leuS 875347 leuS Mycoplasma genitalium G37 leucyl-tRNA synthetase NP_072933.1 322433 R 243273 CDS NP_072934.1 12045123 875343 complement(324812..325159) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 325159 875343 MG_267 Mycoplasma genitalium G37 hypothetical protein NP_072934.1 324812 R 243273 CDS NP_072935.1 12045124 875387 complement(325193..325879) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 325879 875387 MG_268 Mycoplasma genitalium G37 hypothetical protein NP_072935.1 325193 R 243273 CDS NP_072936.1 12045125 875386 complement(326030..327052) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 327052 875386 MG_269 Mycoplasma genitalium G37 hypothetical protein NP_072936.1 326030 R 243273 CDS NP_072937.1 12045126 875385 complement(327433..328443) 1 NC_000908.2 identified by sequence similarity; lipoyltransferase/lipoate-protein ligase 328443 lplA 875385 lplA Mycoplasma genitalium G37 lipoyltransferase/lipoate-protein ligase NP_072937.1 327433 R 243273 CDS NP_072938.1 12045127 875384 complement(328454..329827) 1 NC_000908.2 identified by sequence similarity; dihydrolipoamide dehydrogenase 329827 pdhD 875384 pdhD Mycoplasma genitalium G37 dihydrolipoamide dehydrogenase NP_072938.1 328454 R 243273 CDS NP_072939.1 12045128 875388 complement(329831..330985) 1 NC_000908.2 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 330985 pdhC 875388 pdhC Mycoplasma genitalium G37 branched-chain alpha-keto acid dehydrogenase subunit E2 NP_072939.1 329831 R 243273 CDS NP_072940.1 12045129 875399 complement(331235..332215) 1 NC_000908.2 identified by sequence similarity; pyruvate dehydrogenase component E1, beta subunit 332215 pdhB 875399 pdhB Mycoplasma genitalium G37 pyruvate dehydrogenase component E1, beta subunit NP_072940.1 331235 R 243273 CDS NP_072941.1 12045130 875404 complement(332233..333309) 1 NC_000908.2 identified by sequence similarity; pyruvate dehydrogenase component E1, alpha subunit 333309 pdhA 875404 pdhA Mycoplasma genitalium G37 pyruvate dehydrogenase component E1, alpha subunit NP_072941.1 332233 R 243273 CDS NP_072942.2 108885099 875557 complement(333337..334773) 1 NC_000908.2 identified by sequence similarity; NADH oxidase 334773 nox 875557 nox Mycoplasma genitalium G37 NADH oxidase NP_072942.2 333337 R 243273 CDS NP_072943.1 12045132 875405 complement(334856..335398) 1 NC_000908.2 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 335398 875405 MG_276 Mycoplasma genitalium G37 adenine phosphoribosyltransferase NP_072943.1 334856 R 243273 CDS NP_072944.1 12045133 875243 complement(335412..338324) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 338324 875243 MG_277 Mycoplasma genitalium G37 hypothetical protein NP_072944.1 335412 R 243273 CDS NP_072945.1 12045134 875246 338367..340529 1 NC_000908.2 identified by sequence similarity; GTP pyrophosphokinase 340529 relA 875246 relA Mycoplasma genitalium G37 GTP pyrophosphokinase NP_072945.1 338367 D 243273 CDS NP_072946.1 12045135 875248 complement(340526..341182) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 341182 875248 MG_279 Mycoplasma genitalium G37 hypothetical protein NP_072946.1 340526 R 243273 CDS NP_072947.2 108885100 875257 complement(341175..341972) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 341972 875257 MG_280 Mycoplasma genitalium G37 hypothetical protein NP_072947.2 341175 R 243273 CDS NP_072948.1 12045137 875235 complement(342033..343703) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 343703 875235 MG_281 Mycoplasma genitalium G37 hypothetical protein NP_072948.1 342033 R 243273 CDS NP_072949.1 12045138 875338 complement(344365..344850) 1 NC_000908.2 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 344850 greA 875338 greA Mycoplasma genitalium G37 transcription elongation factor GreA NP_072949.1 344365 R 243273 CDS NP_072950.1 12045139 875489 345182..346633 1 NC_000908.2 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 346633 proS 875489 proS Mycoplasma genitalium G37 prolyl-tRNA synthetase NP_072950.1 345182 D 243273 CDS NP_072951.1 12045140 875733 346854..347252 1 NC_000908.2 identified by sequence similarity; hypothetical protein 347252 875733 MG_284 Mycoplasma genitalium G37 hypothetical protein NP_072951.1 346854 D 243273 CDS NP_072952.1 12045141 875726 347215..348258 1 NC_000908.2 identified by sequence similarity; hypothetical protein 348258 875726 MG_285 Mycoplasma genitalium G37 hypothetical protein NP_072952.1 347215 D 243273 CDS NP_072953.1 12045142 875276 348261..348851 1 NC_000908.2 identified by sequence similarity; hypothetical protein 348851 875276 MG_286 Mycoplasma genitalium G37 hypothetical protein NP_072953.1 348261 D 243273 CDS NP_072954.1 12045143 875396 348883..349137 1 NC_000908.2 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 349137 875396 MG_287 Mycoplasma genitalium G37 acyl carrier protein NP_072954.1 348883 D 243273 CDS NP_072955.1 12045144 875389 354024..355130 1 NC_000908.2 identified by sequence similarity; phosphonate ABC transporter substrate-binding protein 355130 875389 MG_289 Mycoplasma genitalium G37 phosphonate ABC transporter substrate-binding protein NP_072955.1 354024 D 243273 CDS NP_072956.1 12045145 875241 355120..355857 1 NC_000908.2 identified by sequence similarity; phosphonate ABC transporter ATP-binding protein 355857 875241 MG_290 Mycoplasma genitalium G37 phosphonate ABC transporter ATP-binding protein NP_072956.1 355120 D 243273 CDS NP_072957.1 12045146 875242 355847..357478 1 NC_000908.2 identified by sequence similarity; phosphonate ABC transporter permease 357478 875242 MG_291 Mycoplasma genitalium G37 phosphonate ABC transporter permease NP_072957.1 355847 D 243273 CDS NP_072958.1 12045147 875398 complement(357475..357891) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 357891 875398 MG_505 Mycoplasma genitalium G37 hypothetical protein NP_072958.1 357475 R 243273 CDS NP_072959.1 12045148 875339 complement(357891..360593) 1 NC_000908.2 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 360593 alaS 875339 alaS Mycoplasma genitalium G37 alanyl-tRNA synthetase NP_072959.1 357891 R 243273 CDS NP_072960.1 12045149 875409 complement(360651..361385) 1 NC_000908.2 identified by sequence similarity; glycerophosphoryl diester phosphodiesterase family protein 361385 875409 MG_293 Mycoplasma genitalium G37 glycerophosphoryl diester phosphodiesterase family protein NP_072960.1 360651 R 243273 CDS NP_072961.1 12045150 875713 complement(361378..362802) 1 NC_000908.2 identified by sequence similarity; major facilitator superfamily protein 362802 875713 MG_294 Mycoplasma genitalium G37 major facilitator superfamily protein NP_072961.1 361378 R 243273 CDS NP_072962.1 12045151 875686 complement(362920..364023) 1 NC_000908.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 364023 mnmA 875686 mnmA Mycoplasma genitalium G37 tRNA-specific 2-thiouridylase MnmA NP_072962.1 362920 R 243273 CDS NP_072963.1 12045152 875258 complement(364026..364415) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 364415 875258 MG_296 Mycoplasma genitalium G37 hypothetical protein NP_072963.1 364026 R 243273 CDS NP_072964.1 12045153 875259 complement(364535..365575) 1 NC_000908.2 identified by sequence similarity; signal recognition particle-docking protein FtsY 365575 ftsY 875259 ftsY Mycoplasma genitalium G37 signal recognition particle-docking protein FtsY NP_072964.1 364535 R 243273 CDS NP_072965.1 12045154 875295 complement(365582..368530) 1 NC_000908.2 identified by sequence similarity; chromosome segregation protein SMC 368530 875295 MG_298 Mycoplasma genitalium G37 chromosome segregation protein SMC NP_072965.1 365582 R 243273 CDS NP_072966.1 12045155 875564 complement(368733..369695) 1 NC_000908.2 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 369695 eutD 875564 eutD Mycoplasma genitalium G37 phosphotransacetylase NP_072966.1 368733 R 243273 CDS NP_072967.2 108885101 875582 complement(369713..370948) 1 NC_000908.2 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 370948 pgk 875582 pgk Mycoplasma genitalium G37 phosphoglycerate kinase NP_072967.2 369713 R 243273 CDS NP_072968.1 12045157 875428 complement(370950..371963) 1 NC_000908.2 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 371963 gap 875428 gap Mycoplasma genitalium G37 glyceraldehyde-3-phosphate dehydrogenase NP_072968.1 370950 R 243273 CDS NP_072969.1 12045158 875429 complement(371994..372947) 1 NC_000908.2 identified by sequence similarity; metal ABC transporter permease 372947 875429 MG_302 Mycoplasma genitalium G37 metal ABC transporter permease NP_072969.1 371994 R 243273 CDS NP_072970.1 12045159 875250 complement(372926..373999) 1 NC_000908.2 identified by sequence similarity; metal ABC transporter ATP-binding protein 373999 875250 MG_303 Mycoplasma genitalium G37 metal ABC transporter ATP-binding protein NP_072970.1 372926 R 243273 CDS NP_072971.2 108885102 875412 complement(373981..374793) 1 NC_000908.2 identified by sequence similarity; metal ABC transporter ATP-binding protein 374793 875412 MG_304 Mycoplasma genitalium G37 metal ABC transporter ATP-binding protein NP_072971.2 373981 R 243273 CDS NP_072972.1 12045161 875435 complement(374919..376706) 1 NC_000908.2 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 376706 dnaK 875435 dnaK Mycoplasma genitalium G37 molecular chaperone DnaK NP_072972.1 374919 R 243273 CDS NP_072973.1 12045162 875436 complement(376794..377975) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 377975 875436 MG_306 Mycoplasma genitalium G37 hypothetical protein NP_072973.1 376794 R 243273 CDS NP_072974.1 12045163 875391 complement(377975..381508) 1 NC_000908.2 identified by sequence similarity; lipoprotein 381508 875391 MG_307 Mycoplasma genitalium G37 lipoprotein NP_072974.1 377975 R 243273 CDS NP_072975.1 12045164 875443 complement(381493..382725) 1 NC_000908.2 identified by sequence similarity; DEAD-box ATP dependent DNA helicase 382725 875443 MG_308 Mycoplasma genitalium G37 DEAD-box ATP dependent DNA helicase NP_072975.1 381493 R 243273 CDS NP_072976.2 108885103 875555 complement(382732..386409) 1 NC_000908.2 identified by sequence similarity; lipoprotein 386409 875555 MG_309 Mycoplasma genitalium G37 lipoprotein NP_072976.2 382732 R 243273 CDS NP_072977.1 12045166 875556 386463..387269 1 NC_000908.2 identified by sequence similarity; alpha/beta fold family hydrolase 387269 875556 MG_310 Mycoplasma genitalium G37 alpha/beta fold family hydrolase NP_072977.1 386463 D 243273 CDS NP_072978.1 12045167 875565 complement(387276..387893) 1 NC_000908.2 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 387893 rpsD 875565 rpsD Mycoplasma genitalium G37 30S ribosomal protein S4 NP_072978.1 387276 R 243273 CDS NP_072979.1 12045168 875568 complement(387916..391335) 1 NC_000908.2 identified by sequence similarity; HMW1 cytadherence accessory protein 391335 hmw1 875568 hmw1 Mycoplasma genitalium G37 HMW1 cytadherence accessory protein NP_072979.1 387916 R 243273 CDS NP_072980.1 12045169 875569 complement(391395..392258) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 392258 875569 MG_313 Mycoplasma genitalium G37 hypothetical protein NP_072980.1 391395 R 243273 CDS NP_072981.1 12045170 875244 complement(392303..393634) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 393634 875244 MG_314 Mycoplasma genitalium G37 hypothetical protein NP_072981.1 392303 R 243273 CDS NP_072982.1 12045171 875245 complement(393658..394551) 1 NC_000908.2 identified by sequence similarity; DNA polymerase III subunit delta 394551 875245 MG_315 Mycoplasma genitalium G37 DNA polymerase III subunit delta NP_072982.1 393658 R 243273 CDS NP_072983.1 12045172 875578 complement(394475..395584) 1 NC_000908.2 identified by sequence similarity; ComEC/Rec2-related protein 395584 875578 MG_316 Mycoplasma genitalium G37 ComEC/Rec2-related protein NP_072983.1 394475 R 243273 CDS NP_072984.1 12045173 875571 complement(395625..397424) 1 NC_000908.2 identified by sequence similarity; HMW3 cytadherence accessory protein 397424 hmw3 875571 hmw3 Mycoplasma genitalium G37 HMW3 cytadherence accessory protein NP_072984.1 395625 R 243273 CDS NP_072985.1 12045174 875572 complement(397439..398281) 1 NC_000908.2 identified by sequence similarity; P32 adhesin 398281 875572 MG_318 Mycoplasma genitalium G37 P32 adhesin NP_072985.1 397439 R 243273 CDS NP_072986.1 12045175 875559 complement(398298..398834) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 398834 875559 MG_319 Mycoplasma genitalium G37 hypothetical protein NP_072986.1 398298 R 243273 CDS NP_072987.1 12045176 875560 complement(398938..399798) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 399798 875560 MG_320 Mycoplasma genitalium G37 hypothetical protein NP_072987.1 398938 R 243273 CDS NP_072989.1 12045178 875580 complement(400119..402923) 1 NC_000908.2 identified by sequence similarity; lipoprotein 402923 875580 MG_321 Mycoplasma genitalium G37 lipoprotein NP_072989.1 400119 R 243273 CDS NP_072990.1 12045179 875495 complement(403723..405399) 1 NC_000908.2 identified by sequence similarity; TrkH family potassium uptake protein 405399 875495 MG_322 Mycoplasma genitalium G37 TrkH family potassium uptake protein NP_072990.1 403723 R 243273 CDS NP_072991.1 12045180 875521 405456..406139 1 NC_000908.2 identified by sequence similarity; TrkA family potassium uptake protein 406139 875521 MG_323 Mycoplasma genitalium G37 TrkA family potassium uptake protein NP_072991.1 405456 D 243273 CDS NP_072992.1 12045181 875522 complement(406975..407784) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 407784 875522 MG_515 Mycoplasma genitalium G37 hypothetical protein NP_072992.1 406975 R 243273 CDS NP_072993.1 12045182 875523 complement(407729..408793) 1 NC_000908.2 identified by sequence similarity; M24 family metallopeptidase 408793 pepP 875523 pepP Mycoplasma genitalium G37 M24 family metallopeptidase NP_072993.1 407729 R 243273 CDS NP_072994.1 12045183 875268 complement(408793..408954) 1 NC_000908.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 408954 rpmG 875268 rpmG Mycoplasma genitalium G37 50S ribosomal protein L33 NP_072994.1 408793 R 243273 CDS NP_072995.1 12045184 875269 complement(408971..409858) 1 NC_000908.2 identified by sequence similarity; degV family protein 409858 875269 MG_326 Mycoplasma genitalium G37 degV family protein NP_072995.1 408971 R 243273 CDS NP_072996.1 12045185 875487 complement(409871..410677) 1 NC_000908.2 identified by sequence similarity; alpha/beta fold family hydrolase 410677 875487 MG_327 Mycoplasma genitalium G37 alpha/beta fold family hydrolase NP_072996.1 409871 R 243273 CDS NP_072997.1 12045186 875488 complement(410664..412934) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 412934 875488 MG_328 Mycoplasma genitalium G37 hypothetical protein NP_072997.1 410664 R 243273 CDS NP_072998.1 12045187 875272 complement(412973..414319) 1 NC_000908.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 414319 engA 875272 engA Mycoplasma genitalium G37 GTP-binding protein EngA NP_072998.1 412973 R 243273 CDS NP_072999.1 12045188 875273 complement(414323..414976) 1 NC_000908.2 identified by sequence similarity; cytidylate kinase 414976 cmk 875273 cmk Mycoplasma genitalium G37 cytidylate kinase NP_072999.1 414323 R 243273 CDS NP_073000.1 12045189 875439 complement(414985..415623) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 415623 875439 MG_331 Mycoplasma genitalium G37 hypothetical protein NP_073000.1 414985 R 243273 CDS NP_073001.1 12045190 875440 complement(415611..416330) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 416330 875440 MG_332 Mycoplasma genitalium G37 hypothetical protein NP_073001.1 415611 R 243273 CDS NP_073002.1 12045191 875510 complement(416967..419480) 1 NC_000908.2 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 419480 valS 875510 valS Mycoplasma genitalium G37 valyl-tRNA synthetase NP_073002.1 416967 R 243273 CDS NP_073003.1 12045192 875511 complement(419470..420045) 1 NC_000908.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 420045 engB 875511 engB Mycoplasma genitalium G37 ribosome biogenesis GTP-binding protein YsxC NP_073003.1 419470 R 243273 CDS NP_073004.1 12045193 875262 complement(420053..420274) 1 NC_000908.2 hypothetical protein; identified by GeneMark; hypothetical protein 420274 875262 MG_516 Mycoplasma genitalium G37 hypothetical protein NP_073004.1 420053 R 243273 CDS NP_073005.1 12045194 875263 420333..421358 1 NC_000908.2 identified by sequence similarity; glycosyl transferase, group 2 family protein 421358 875263 MG_517 Mycoplasma genitalium G37 glycosyl transferase, group 2 family protein NP_073005.1 420333 D 243273 CDS NP_073006.1 12045195 875461 421467..422693 1 NC_000908.2 identified by sequence similarity; aminotransferase, class V 422693 nifS 875461 nifS Mycoplasma genitalium G37 aminotransferase, class V NP_073006.1 421467 D 243273 CDS NP_073007.1 12045196 875462 422697..423113 1 NC_000908.2 identified by sequence similarity; hypothetical protein 423113 875462 MG_337 Mycoplasma genitalium G37 hypothetical protein NP_073007.1 422697 D 243273 CDS NP_073008.2 108885104 875419 complement(423100..426912) 1 NC_000908.2 identified by sequence similarity; lipoprotein 426912 875419 MG_338 Mycoplasma genitalium G37 lipoprotein NP_073008.2 423100 R 243273 CDS NP_073009.1 12045198 875420 complement(427090..428112) 1 NC_000908.2 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 428112 recA 875420 recA Mycoplasma genitalium G37 recombinase A NP_073009.1 427090 R 243273 CDS NP_073010.2 108885105 875481 complement(430580..434458) 1 NC_000908.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 434458 rpoC 875481 rpoC Mycoplasma genitalium G37 DNA-directed RNA polymerase subunit beta' NP_073010.2 430580 R 243273 CDS NP_073011.1 12045200 875482 complement(434468..438640) 1 NC_000908.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 438640 rpoB 875482 rpoB Mycoplasma genitalium G37 DNA-directed RNA polymerase subunit beta NP_073011.1 434468 R 243273 CDS NP_073012.1 12045201 875477 complement(438730..439236) 1 NC_000908.2 identified by sequence similarity; NADPH-dependent FMN reductase domain-containing protein 439236 875477 MG_342 Mycoplasma genitalium G37 NADPH-dependent FMN reductase domain-containing protein NP_073012.1 438730 R 243273 CDS NP_073013.1 12045202 875478 complement(439315..440355) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 440355 875478 MG_343 Mycoplasma genitalium G37 hypothetical protein NP_073013.1 439315 R 243273 CDS NP_073014.1 12045203 875479 complement(440359..441180) 1 NC_000908.2 identified by sequence similarity; alpha/beta fold family hydrolase 441180 875479 MG_344 Mycoplasma genitalium G37 alpha/beta fold family hydrolase NP_073014.1 440359 R 243273 CDS NP_073015.2 108885106 875496 complement(441191..443878) 1 NC_000908.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 443878 ileS 875496 ileS Mycoplasma genitalium G37 isoleucyl-tRNA synthetase NP_073015.2 441191 R 243273 CDS NP_073016.1 12045205 875497 443922..444422 1 NC_000908.2 identified by sequence similarity; RNA methyltransferase 444422 875497 MG_346 Mycoplasma genitalium G37 RNA methyltransferase NP_073016.1 443922 D 243273 CDS NP_073017.1 12045206 875414 444413..445045 1 NC_000908.2 identified by sequence similarity; tRNA (guanine-N(7)-)-methyltransferase 445045 875414 MG_347 Mycoplasma genitalium G37 tRNA (guanine-N(7)-)-methyltransferase NP_073017.1 444413 D 243273 CDS NP_073018.1 12045207 875457 complement(445197..446165) 1 NC_000908.2 identified by sequence similarity; lipoprotein 446165 875457 MG_348 Mycoplasma genitalium G37 lipoprotein NP_073018.1 445197 R 243273 CDS NP_073019.1 12045208 875459 446576..447790 1 NC_000908.2 identified by sequence similarity; hypothetical protein 447790 875459 MG_349 Mycoplasma genitalium G37 hypothetical protein NP_073019.1 446576 D 243273 CDS NP_073020.1 12045209 875449 447790..448725 1 NC_000908.2 identified by sequence similarity; hypothetical protein 448725 875449 MG_350 Mycoplasma genitalium G37 hypothetical protein NP_073020.1 447790 D 243273 CDS NP_073021.1 12045210 875278 complement(448943..449617) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 449617 875278 MG_521 Mycoplasma genitalium G37 hypothetical protein NP_073021.1 448943 R 243273 CDS NP_073022.1 12045211 875279 449665..450219 1 NC_000908.2 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 450219 ppa 875279 ppa Mycoplasma genitalium G37 inorganic pyrophosphatase NP_073022.1 449665 D 243273 CDS NP_073023.1 12045212 875290 450222..450722 1 NC_000908.2 identified by sequence similarity; recombination protein U 450722 875290 MG_352 Mycoplasma genitalium G37 recombination protein U NP_073023.1 450222 D 243273 CDS NP_073024.1 12045213 875291 complement(450719..451048) 1 NC_000908.2 identified by sequence similarity; DNA-binding protein HU 451048 875291 MG_353 Mycoplasma genitalium G37 DNA-binding protein HU NP_073024.1 450719 R 243273 CDS NP_073025.1 12045214 875344 451197..451610 1 NC_000908.2 identified by sequence similarity; hypothetical protein 451610 875344 MG_354 Mycoplasma genitalium G37 hypothetical protein NP_073025.1 451197 D 243273 CDS NP_073026.1 12045215 875345 complement(451613..453757) 1 NC_000908.2 identified by sequence similarity; ATP-dependent Clp protease ATPase subunit 453757 clpB 875345 clpB Mycoplasma genitalium G37 ATP-dependent Clp protease ATPase subunit NP_073026.1 451613 R 243273 CDS NP_073027.1 12045216 875346 complement(453911..454753) 1 NC_000908.2 identified by sequence similarity; choline/ethanolamine kinase 454753 875346 MG_356 Mycoplasma genitalium G37 choline/ethanolamine kinase NP_073027.1 453911 R 243273 CDS NP_073028.1 12045217 875501 complement(454766..455947) 1 NC_000908.2 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 455947 ackA 875501 ackA Mycoplasma genitalium G37 acetate kinase NP_073028.1 454766 R 243273 CDS NP_073029.2 108885107 875502 456755..457372 1 NC_000908.2 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 457372 ruvA 875502 ruvA Mycoplasma genitalium G37 Holliday junction DNA helicase RuvA NP_073029.2 456755 D 243273 CDS NP_073030.1 12045219 875515 457347..458270 1 NC_000908.2 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 458270 ruvB 875515 ruvB Mycoplasma genitalium G37 Holliday junction DNA helicase RuvB NP_073030.1 457347 D 243273 CDS NP_073031.1 12045220 875516 complement(458260..459495) 1 NC_000908.2 identified by sequence similarity; ImpB/MucB/SamB family protein 459495 875516 MG_360 Mycoplasma genitalium G37 ImpB/MucB/SamB family protein NP_073031.1 458260 R 243273 CDS NP_073032.1 12045221 875505 459615..460103 1 NC_000908.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 460103 rplJ 875505 rplJ Mycoplasma genitalium G37 50S ribosomal protein L10 NP_073032.1 459615 D 243273 CDS NP_073033.1 12045222 875506 460126..460494 1 NC_000908.2 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 460494 rplL 875506 rplL Mycoplasma genitalium G37 50S ribosomal protein L7/L12 NP_073033.1 460126 D 243273 CDS NP_073034.1 12045223 875222 460497..460670 1 NC_000908.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 460670 rpmF 875222 rpmF Mycoplasma genitalium G37 50S ribosomal protein L32 NP_073034.1 460497 D 243273 CDS NP_073035.1 12045224 875223 complement(460685..460951) 1 NC_000908.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 460951 rpsT 875223 rpsT Mycoplasma genitalium G37 30S ribosomal protein S20 NP_073035.1 460685 R 243273 CDS NP_073036.1 12045225 875423 461015..461689 1 NC_000908.2 identified by sequence similarity; hypothetical protein 461689 875423 MG_364 Mycoplasma genitalium G37 hypothetical protein NP_073036.1 461015 D 243273 CDS NP_073037.1 12045226 875424 461682..462617 1 NC_000908.2 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 462617 fmt 875424 fmt Mycoplasma genitalium G37 methionyl-tRNA formyltransferase NP_073037.1 461682 D 243273 CDS NP_073038.1 12045227 875425 462619..464622 1 NC_000908.2 identified by sequence similarity; hypothetical protein 464622 875425 MG_366 Mycoplasma genitalium G37 hypothetical protein NP_073038.1 462619 D 243273 CDS NP_073039.1 12045228 875426 complement(464646..465434) 1 NC_000908.2 identified by sequence similarity; ribonuclease III 465434 rnc 875426 rnc Mycoplasma genitalium G37 ribonuclease III NP_073039.1 464646 R 243273 CDS NP_073040.1 12045229 875490 complement(465424..466410) 1 NC_000908.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 466410 plsX 875490 plsX Mycoplasma genitalium G37 glycerol-3-phosphate acyltransferase PlsX NP_073040.1 465424 R 243273 CDS NP_073041.1 12045230 875491 complement(466410..468083) 1 NC_000908.2 identified by sequence similarity; DAK2 domain-containing protein 468083 875491 MG_369 Mycoplasma genitalium G37 DAK2 domain-containing protein NP_073041.1 466410 R 243273 CDS NP_073042.1 12045231 875682 complement(468152..469123) 1 NC_000908.2 identified by sequence similarity; RluA family pseudouridine synthase 469123 875682 MG_370 Mycoplasma genitalium G37 RluA family pseudouridine synthase NP_073042.1 468152 R 243273 CDS NP_073043.1 12045232 875683 complement(469110..470084) 1 NC_000908.2 identified by sequence similarity; DHH family protein 470084 875683 MG_371 Mycoplasma genitalium G37 DHH family protein NP_073043.1 469110 R 243273 CDS NP_073044.1 12045233 875684 complement(470077..471234) 1 NC_000908.2 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 471234 guaA 875684 guaA Mycoplasma genitalium G37 thiamine biosynthesis protein ThiI NP_073044.1 470077 R 243273 CDS NP_073045.1 12045234 875680 complement(471221..472066) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 472066 875680 MG_373 Mycoplasma genitalium G37 hypothetical protein NP_073045.1 471221 R 243273 CDS NP_073046.1 12045235 875681 complement(472067..472891) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 472891 875681 MG_374 Mycoplasma genitalium G37 hypothetical protein NP_073046.1 472067 R 243273 CDS NP_073047.1 12045236 875678 complement(472884..474578) 1 NC_000908.2 identified by sequence similarity; threonyl-tRNA synthetase 474578 thrS 875678 thrS Mycoplasma genitalium G37 threonyl-tRNA synthetase NP_073047.1 472884 R 243273 CDS NP_073048.1 12045237 875679 complement(474578..474892) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 474892 875679 MG_376 Mycoplasma genitalium G37 hypothetical protein NP_073048.1 474578 R 243273 CDS NP_073049.1 12045238 875676 complement(474898..475479) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 475479 875676 MG_377 Mycoplasma genitalium G37 hypothetical protein NP_073049.1 474898 R 243273 CDS NP_073050.1 12045239 875677 complement(475526..477139) 1 NC_000908.2 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 477139 argS 875677 argS Mycoplasma genitalium G37 arginyl-tRNA synthetase NP_073050.1 475526 R 243273 CDS NP_073051.1 12045240 875674 477168..479006 1 NC_000908.2 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 479006 gidA 875674 gidA Mycoplasma genitalium G37 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NP_073051.1 477168 D 243273 CDS NP_073052.1 12045241 875675 478999..479577 1 NC_000908.2 identified by sequence similarity; methyltransferase GidB 479577 gidB 875675 gidB Mycoplasma genitalium G37 methyltransferase GidB NP_073052.1 478999 D 243273 CDS NP_073053.1 12045242 875671 479570..480226 1 NC_000908.2 identified by sequence similarity; hypothetical protein 480226 875671 MG_381 Mycoplasma genitalium G37 hypothetical protein NP_073053.1 479570 D 243273 CDS NP_073054.1 12045243 875673 480691..481332 1 NC_000908.2 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 481332 udk 875673 udk Mycoplasma genitalium G37 uridine kinase NP_073054.1 480691 D 243273 CDS NP_073055.1 12045244 875669 complement(481329..482075) 1 NC_000908.2 identified by sequence similarity; NH(3)-dependent NAD+ synthetase 482075 875669 MG_383 Mycoplasma genitalium G37 NH(3)-dependent NAD+ synthetase NP_073055.1 481329 R 243273 CDS NP_073056.1 12045245 875670 complement(482068..483369) 1 NC_000908.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 483369 obgE 875670 obgE Mycoplasma genitalium G37 GTPase ObgE NP_073056.1 482068 R 243273 CDS NP_073057.1 12045246 875667 complement(483369..483818) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 483818 875667 MG_524 Mycoplasma genitalium G37 hypothetical protein NP_073057.1 483369 R 243273 CDS NP_073058.1 12045247 875668 complement(483989..484699) 1 NC_000908.2 identified by sequence similarity; glycerophosphoryl diester phosphodiesterase family protein 484699 875668 MG_385 Mycoplasma genitalium G37 glycerophosphoryl diester phosphodiesterase family protein NP_073058.1 483989 R 243273 CDS NP_073059.1 12045248 875665 complement(484702..489552) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 489552 875665 MG_386 Mycoplasma genitalium G37 hypothetical protein NP_073059.1 484702 R 243273 CDS NP_073060.1 12045249 875666 complement(489839..490711) 1 NC_000908.2 identified by sequence similarity; GTP-binding protein Era 490711 era 875666 era Mycoplasma genitalium G37 GTP-binding protein Era NP_073060.1 489839 R 243273 CDS NP_073061.2 108885108 875663 complement(490699..491163) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 491163 875663 MG_388 Mycoplasma genitalium G37 hypothetical protein NP_073061.2 490699 R 243273 CDS NP_073062.1 12045251 875664 complement(491147..491530) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 491530 875664 MG_389 Mycoplasma genitalium G37 hypothetical protein NP_073062.1 491147 R 243273 CDS NP_073063.1 12045252 875660 complement(491534..493516) 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein/permease 493516 875660 MG_390 Mycoplasma genitalium G37 ABC transporter ATP-binding protein/permease NP_073063.1 491534 R 243273 CDS NP_073064.1 12045253 875661 complement(493624..494967) 1 NC_000908.2 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 494967 875661 MG_391 Mycoplasma genitalium G37 leucyl aminopeptidase NP_073064.1 493624 R 243273 CDS NP_073065.2 108885109 875662 complement(494984..496615) 1 NC_000908.2 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 496615 groEL 875662 groEL Mycoplasma genitalium G37 chaperonin GroEL NP_073065.2 494984 R 243273 CDS NP_073066.1 12045255 875658 complement(496628..496960) 1 NC_000908.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP-binding and hydrolysis in the trans ring; co-chaperonin GroES 496960 groES 875658 groES Mycoplasma genitalium G37 co-chaperonin GroES NP_073066.1 496628 R 243273 CDS NP_073067.1 12045256 875659 complement(497086..498306) 1 NC_000908.2 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 498306 glyA 875659 glyA Mycoplasma genitalium G37 serine hydroxymethyltransferase NP_073067.1 497086 R 243273 CDS NP_073068.1 12045257 875656 complement(498316..499890) 1 NC_000908.2 identified by sequence similarity; lipoprotein 499890 875656 MG_395 Mycoplasma genitalium G37 lipoprotein NP_073068.1 498316 R 243273 CDS NP_073069.1 12045258 875657 complement(500261..500719) 1 NC_000908.2 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 500719 875657 MG_396 Mycoplasma genitalium G37 ribose-5-phosphate isomerase B NP_073069.1 500261 R 243273 CDS NP_073070.1 12045259 875654 complement(500720..502420) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 502420 875654 MG_397 Mycoplasma genitalium G37 hypothetical protein NP_073070.1 500720 R 243273 CDS NP_073071.1 12045260 875655 complement(502422..502823) 1 NC_000908.2 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 502823 atpC 875655 atpC Mycoplasma genitalium G37 F0F1 ATP synthase subunit epsilon NP_073071.1 502422 R 243273 CDS NP_073072.1 12045261 875652 complement(502828..504258) 1 NC_000908.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 504258 atpD 875652 atpD Mycoplasma genitalium G37 F0F1 ATP synthase subunit beta NP_073072.1 502828 R 243273 CDS NP_073073.1 12045262 875653 complement(504260..505099) 1 NC_000908.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 505099 atpG 875653 atpG Mycoplasma genitalium G37 F0F1 ATP synthase subunit gamma NP_073073.1 504260 R 243273 CDS NP_073074.1 12045263 875650 complement(505099..506655) 1 NC_000908.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 506655 atpA 875650 atpA Mycoplasma genitalium G37 F0F1 ATP synthase subunit alpha NP_073074.1 505099 R 243273 CDS NP_073075.1 12045264 875651 complement(506671..507201) 1 NC_000908.2 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 507201 atpH 875651 atpH Mycoplasma genitalium G37 F0F1 ATP synthase subunit delta NP_073075.1 506671 R 243273 CDS NP_073076.1 12045265 875648 complement(507194..507820) 1 NC_000908.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 507820 atpF 875648 atpF Mycoplasma genitalium G37 F0F1 ATP synthase subunit B NP_073076.1 507194 R 243273 CDS NP_073077.1 12045266 875649 complement(507823..508131) 1 NC_000908.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 508131 atpE 875649 atpE Mycoplasma genitalium G37 F0F1 ATP synthase subunit C NP_073077.1 507823 R 243273 CDS NP_073078.1 12045267 875646 complement(508134..509012) 1 NC_000908.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 509012 atpB 875646 atpB Mycoplasma genitalium G37 F0F1 ATP synthase subunit A NP_073078.1 508134 R 243273 CDS NP_073079.2 108885110 875647 complement(508978..509454) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 509454 875647 MG_406 Mycoplasma genitalium G37 hypothetical protein NP_073079.2 508978 R 243273 CDS NP_073080.1 12045269 875644 complement(509460..510836) 1 NC_000908.2 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 510836 eno 875644 eno Mycoplasma genitalium G37 phosphopyruvate hydratase NP_073080.1 509460 R 243273 CDS NP_073081.1 12045270 875645 510903..511376 1 NC_000908.2 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 511376 pmsR 875645 pmsR Mycoplasma genitalium G37 methionine sulfoxide reductase A NP_073081.1 510903 D 243273 CDS NP_073082.1 12045271 875641 complement(511373..512050) 1 NC_000908.2 identified by sequence similarity; phosphate transport system regulatory protein PhoU 512050 875641 MG_409 Mycoplasma genitalium G37 phosphate transport system regulatory protein PhoU NP_073082.1 511373 R 243273 CDS NP_073083.1 12045272 875642 complement(512053..513042) 1 NC_000908.2 identified by sequence similarity; phosphate ABC transporter ATP-binding protein 513042 pstB 875642 pstB Mycoplasma genitalium G37 phosphate ABC transporter ATP-binding protein NP_073083.1 512053 R 243273 CDS NP_073084.1 12045273 875643 complement(513027..514991) 1 NC_000908.2 identified by sequence similarity; phosphate ABC transporter permease 514991 pstA 875643 pstA Mycoplasma genitalium G37 phosphate ABC transporter permease NP_073084.1 513027 R 243273 CDS NP_073085.1 12045274 875639 complement(514991..516124) 1 NC_000908.2 identified by sequence similarity; phosphate ABC transporter substrate-binding protein 516124 875639 MG_412 Mycoplasma genitalium G37 phosphate ABC transporter substrate-binding protein NP_073085.1 514991 R 243273 CDS NP_073086.1 12045275 875640 complement(516245..519355) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 519355 875640 MG_414 Mycoplasma genitalium G37 hypothetical protein NP_073086.1 516245 R 243273 CDS NP_073087.2 108885111 875637 complement(519420..521414) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 521414 875637 MG_525 Mycoplasma genitalium G37 hypothetical protein NP_073087.2 519420 R 243273 CDS NP_073088.1 12045277 875638 complement(521470..521868) 1 NC_000908.2 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 521868 rpsI 875638 rpsI Mycoplasma genitalium G37 30S ribosomal protein S9 NP_073088.1 521470 R 243273 CDS NP_073089.1 12045278 875635 complement(521874..522314) 1 NC_000908.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 522314 rplM 875635 rplM Mycoplasma genitalium G37 50S ribosomal protein L13 NP_073089.1 521874 R 243273 CDS NP_073090.2 108885112 875636 complement(522352..524145) 1 NC_000908.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau 524145 875636 MG_419 Mycoplasma genitalium G37 DNA polymerase III subunits gamma/tau NP_073090.2 522352 R 243273 CDS NP_073092.1 12045281 875634 complement(524151..527015) 1 NC_000908.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 527015 uvrA 875634 uvrA Mycoplasma genitalium G37 excinuclease ABC subunit A NP_073092.1 524151 R 243273 CDS NP_073093.1 12045282 875630 complement(526987..529494) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 529494 875630 MG_422 Mycoplasma genitalium G37 hypothetical protein NP_073093.1 526987 R 243273 CDS NP_073094.1 12045283 875631 complement(529532..531217) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 531217 875631 MG_423 Mycoplasma genitalium G37 hypothetical protein NP_073094.1 529532 R 243273 CDS NP_073095.1 12045284 875632 complement(531220..531480) 1 NC_000908.2 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 531480 rpsO 875632 rpsO Mycoplasma genitalium G37 30S ribosomal protein S15 NP_073095.1 531220 R 243273 CDS NP_073096.1 12045285 875628 531669..533018 1 NC_000908.2 identified by sequence similarity; DEAD-box ATP dependent DNA helicase 533018 deaD 875628 deaD Mycoplasma genitalium G37 DEAD-box ATP dependent DNA helicase NP_073096.1 531669 D 243273 CDS NP_073097.1 12045286 875629 533041..533235 1 NC_000908.2 required for 70S ribosome assembly; 50S ribosomal protein L28 533235 rpmB 875629 rpmB Mycoplasma genitalium G37 50S ribosomal protein L28 NP_073097.1 533041 D 243273 CDS NP_073098.1 12045287 875626 533271..533696 1 NC_000908.2 identified by sequence similarity; OsmC-like protein 533696 875626 MG_427 Mycoplasma genitalium G37 OsmC-like protein NP_073098.1 533271 D 243273 CDS NP_073099.1 12045288 875627 533807..534322 1 NC_000908.2 identified by sequence similarity; LuxR regulatory protein 534322 875627 MG_428 Mycoplasma genitalium G37 LuxR regulatory protein NP_073099.1 533807 D 243273 CDS NP_073100.1 12045289 875624 complement(534319..536037) 1 NC_000908.2 identified by sequence similarity; phosphoenolpyruvate-protein phosphotransferase 536037 ptsI 875624 ptsI Mycoplasma genitalium G37 phosphoenolpyruvate-protein phosphotransferase NP_073100.1 534319 R 243273 CDS NP_073101.2 108885113 875625 complement(536041..537564) 1 NC_000908.2 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 537564 pgm 875625 pgm Mycoplasma genitalium G37 phosphoglyceromutase NP_073101.2 536041 R 243273 CDS NP_073102.1 12045291 875622 complement(537557..538291) 1 NC_000908.2 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 538291 tpiA 875622 tpiA Mycoplasma genitalium G37 triosephosphate isomerase NP_073102.1 537557 R 243273 CDS NP_073103.1 12045292 875623 complement(538351..539547) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 539547 875623 MG_432 Mycoplasma genitalium G37 hypothetical protein NP_073103.1 538351 R 243273 CDS NP_073104.1 12045293 875620 539633..540529 1 NC_000908.2 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 540529 tsf 875620 tsf Mycoplasma genitalium G37 elongation factor Ts NP_073104.1 539633 D 243273 CDS NP_073105.1 12045294 875621 540510..541241 1 NC_000908.2 identified by sequence similarity; uridylate kinase 541241 pyrH 875621 pyrH Mycoplasma genitalium G37 uridylate kinase NP_073105.1 540510 D 243273 CDS NP_073106.1 12045295 875618 541241..541792 1 NC_000908.2 identified by sequence similarity; ribosome recycling factor 541792 frr 875618 frr Mycoplasma genitalium G37 ribosome recycling factor NP_073106.1 541241 D 243273 CDS NP_073107.2 108885114 875619 541793..542986 1 NC_000908.2 hypothetical protein; identified by GeneMark; phosphatidate cytidylyltransferase 542986 875619 MG_437 Mycoplasma genitalium G37 phosphatidate cytidylyltransferase NP_073107.2 541793 D 243273 CDS NP_073108.1 12045297 875615 543006..544157 1 NC_000908.2 identified by sequence similarity; type I restriction modification DNA specificity domain-containing protein 544157 875615 MG_438 Mycoplasma genitalium G37 type I restriction modification DNA specificity domain-containing protein NP_073108.1 543006 D 243273 CDS NP_073109.1 12045298 875616 complement(544562..545380) 1 NC_000908.2 identified by sequence similarity; lipoprotein 545380 875616 MG_439 Mycoplasma genitalium G37 lipoprotein NP_073109.1 544562 R 243273 CDS NP_073110.1 12045299 875617 complement(545380..546156) 1 NC_000908.2 identified by sequence similarity; lipoprotein 546156 875617 MG_440 Mycoplasma genitalium G37 lipoprotein NP_073110.1 545380 R 243273 CDS NP_073111.1 12045300 875613 complement(546299..546709) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 546709 875613 MG_441 Mycoplasma genitalium G37 hypothetical protein NP_073111.1 546299 R 243273 CDS NP_073112.1 12045301 875614 complement(546880..547692) 1 NC_000908.2 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 547692 rbgA 875614 rbgA Mycoplasma genitalium G37 ribosomal biogenesis GTPase NP_073112.1 546880 R 243273 CDS NP_073113.1 12045302 875611 complement(547664..548851) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 548851 875611 MG_443 Mycoplasma genitalium G37 hypothetical protein NP_073113.1 547664 R 243273 CDS NP_073114.1 12045303 875612 complement(548867..549226) 1 NC_000908.2 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 549226 rplS 875612 rplS Mycoplasma genitalium G37 50S ribosomal protein L19 NP_073114.1 548867 R 243273 CDS NP_073115.1 12045304 875609 complement(549210..549905) 1 NC_000908.2 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 549905 trmD 875609 trmD Mycoplasma genitalium G37 tRNA (guanine-N(1)-)-methyltransferase NP_073115.1 549210 R 243273 CDS NP_073116.2 108885115 875610 complement(549905..550192) 1 NC_000908.2 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 550192 rpsP 875610 rpsP Mycoplasma genitalium G37 30S ribosomal protein S16 NP_073116.2 549905 R 243273 CDS NP_073117.1 12045306 875606 complement(550803..552446) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 552446 875606 MG_447 Mycoplasma genitalium G37 hypothetical protein NP_073117.1 550803 R 243273 CDS NP_073118.1 12045307 875607 complement(552447..552899) 1 NC_000908.2 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 552899 875607 MG_448 Mycoplasma genitalium G37 methionine sulfoxide reductase B NP_073118.1 552447 R 243273 CDS NP_073120.2 108885116 875604 complement(553558..554430) 1 NC_000908.2 identified by sequence similarity; degV family protein 554430 875604 MG_450 Mycoplasma genitalium G37 degV family protein NP_073120.2 553558 R 243273 CDS NP_073121.1 12045310 875605 complement(554430..555614) 1 NC_000908.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 555614 tuf 875605 tuf Mycoplasma genitalium G37 elongation factor Tu NP_073121.1 554430 R 243273 CDS NP_073122.1 12045311 875602 555667..556452 1 NC_000908.2 identified by sequence similarity; hypothetical protein 556452 875602 MG_452 Mycoplasma genitalium G37 hypothetical protein NP_073122.1 555667 D 243273 CDS NP_073123.1 12045312 875603 556437..557315 1 NC_000908.2 identified by sequence similarity; UTP-glucose-1-phosphate uridylyltransferase 557315 gtaB 875603 gtaB Mycoplasma genitalium G37 UTP-glucose-1-phosphate uridylyltransferase NP_073123.1 556437 D 243273 CDS NP_073124.1 12045313 875600 complement(557305..557772) 1 NC_000908.2 identified by sequence similarity; OsmC-like protein 557772 875600 MG_454 Mycoplasma genitalium G37 OsmC-like protein NP_073124.1 557305 R 243273 CDS NP_073125.2 108885117 875601 557759..558949 1 NC_000908.2 identified by sequence similarity; tyrosyl-tRNA synthetase 558949 tyrS 875601 tyrS Mycoplasma genitalium G37 tyrosyl-tRNA synthetase NP_073125.2 557759 D 243273 CDS NP_073126.1 12045315 875597 complement(558939..559943) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 559943 875597 MG_456 Mycoplasma genitalium G37 hypothetical protein NP_073126.1 558939 R 243273 CDS NP_073127.1 12045316 875598 complement(560496..562604) 1 NC_000908.2 identified by sequence similarity; ATP-dependent metalloprotease FtsH 562604 ftsH 875598 ftsH Mycoplasma genitalium G37 ATP-dependent metalloprotease FtsH NP_073127.1 560496 R 243273 CDS NP_073128.1 12045317 875599 complement(562782..563309) 1 NC_000908.2 identified by sequence similarity; hypoxanthine phosphoribosyltransferase 563309 hpt 875599 hpt Mycoplasma genitalium G37 hypoxanthine phosphoribosyltransferase NP_073128.1 562782 R 243273 CDS NP_073129.1 12045318 875595 complement(563311..563820) 1 NC_000908.2 identified by sequence similarity; hypothetical protein 563820 875595 MG_459 Mycoplasma genitalium G37 hypothetical protein NP_073129.1 563311 R 243273 CDS NP_073130.1 12045319 875596 563993..564931 1 NC_000908.2 identified by sequence similarity; lactate dehydrogenase 564931 ldh 875596 ldh Mycoplasma genitalium G37 lactate dehydrogenase NP_073130.1 563993 D 243273 CDS NP_073131.2 108885118 875593 complement(564928..566205) 1 NC_000908.2 identified by sequence similarity; HD domain-containing protein 566205 875593 MG_461 Mycoplasma genitalium G37 HD domain-containing protein NP_073131.2 564928 R 243273 CDS NP_073132.1 12045321 875594 complement(566186..567640) 1 NC_000908.2 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 567640 gltX 875594 gltX Mycoplasma genitalium G37 glutamyl-tRNA synthetase NP_073132.1 566186 R 243273 CDS NP_073133.1 12045322 875591 complement(567627..568406) 1 NC_000908.2 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 568406 ksgA 875591 ksgA Mycoplasma genitalium G37 dimethyladenosine transferase NP_073133.1 567627 R 243273 CDS NP_073134.1 12045323 875592 complement(568399..569556) 1 NC_000908.2 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 569556 875592 MG_464 Mycoplasma genitalium G37 inner membrane protein translocase component YidC NP_073134.1 568399 R 243273 CDS NP_073135.1 12045324 875589 complement(569528..569914) 1 NC_000908.2 identified by sequence similarity; ribonuclease P protein component 569914 rnpA 875589 rnpA Mycoplasma genitalium G37 ribonuclease P protein component NP_073135.1 569528 R 243273 CDS NP_073136.1 12045325 875590 complement(569883..570029) 1 NC_000908.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 570029 rpmH 875590 rpmH Mycoplasma genitalium G37 50S ribosomal protein L34 NP_073136.1 569883 R 243273 CDS NP_073137.1 12045326 875586 complement(570055..570990) 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein 570990 875586 MG_467 Mycoplasma genitalium G37 ABC transporter ATP-binding protein NP_073137.1 570055 R 243273 CDS NP_073138.1 12045327 875587 complement(570994..576345) 1 NC_000908.2 identified by sequence similarity; ABC transporter permease 576345 875587 MG_468 Mycoplasma genitalium G37 ABC transporter permease NP_073138.1 570994 R 243273 CDS NP_073139.1 12045328 875588 complement(576351..577205) 1 NC_000908.2 identified by sequence similarity; ABC transporter ATP-binding protein 577205 875588 MG_526 Mycoplasma genitalium G37 ABC transporter ATP-binding protein NP_073139.1 576351 R 243273 CDS NP_073140.1 12045329 875584 complement(577268..578581) 1 NC_000908.2 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 578581 dnaA 875584 dnaA Mycoplasma genitalium G37 chromosomal replication initiation protein NP_073140.1 577268 R 243273 CDS NP_073141.1 12045330 875585 complement(579224..580033) 1 NC_000908.2 identified by sequence similarity; CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein 580033 soj 875585 soj Mycoplasma genitalium G37 CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein NP_073141.1 579224 R 243273 CDS