-- dump date 20120504_153248 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 243273000001 SEQ_END SEQ_END NC_000908.2 580076 580076 DR NC_000908.2; contig end 580076..580076 Mycoplasma genitalium G37 NP_072661.2 CDS dnaN NC_000908.2 686 1828 D identified by sequence similarity; DNA polymerase III subunit beta 686..1828 Mycoplasma genitalium G37 875454 NP_072662.2 CDS MG_002 NC_000908.2 1828 2760 D identified by sequence similarity; DnaJ domain-containing protein 1828..2760 Mycoplasma genitalium G37 875221 NP_072663.1 CDS gyrB NC_000908.2 2845 4797 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 2845..4797 Mycoplasma genitalium G37 875545 NP_072664.1 CDS gyrA NC_000908.2 4812 7322 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 4812..7322 Mycoplasma genitalium G37 875558 NP_072665.1 CDS serS NC_000908.2 7294 8547 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 7294..8547 Mycoplasma genitalium G37 875703 NP_072666.1 CDS tmk NC_000908.2 8551 9183 D identified by sequence similarity; thymidylate kinase 8551..9183 Mycoplasma genitalium G37 875708 NP_072667.1 CDS MG_007 NC_000908.2 9156 9920 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 9156..9920 Mycoplasma genitalium G37 875716 NP_072668.1 CDS trmE NC_000908.2 9923 11251 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 9923..11251 Mycoplasma genitalium G37 875731 NP_072669.1 CDS MG_009 NC_000908.2 11251 12039 D identified by sequence similarity; TatD family deoxyribonuclease 11251..12039 Mycoplasma genitalium G37 875688 NP_072670.1 CDS MG_010 NC_000908.2 12068 12724 D identified by sequence similarity; DNA primase-related protein 12068..12724 Mycoplasma genitalium G37 875714 NP_072671.1 CDS MG_011 NC_000908.2 12701 13564 R identified by sequence similarity; hypothetical protein complement(12701..13564) Mycoplasma genitalium G37 875236 NP_072672.1 CDS MG_012 NC_000908.2 13569 14432 R identified by sequence similarity; alpha-L-glutamate ligase complement(13569..14432) Mycoplasma genitalium G37 875213 NP_072673.2 CDS folD NC_000908.2 14395 15216 R identified by sequence similarity; methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase complement(14395..15216) Mycoplasma genitalium G37 875696 NP_072674.1 CDS MG_014 NC_000908.2 15555 17426 D identified by sequence similarity; ABC transporter ATP-binding protein/permease 15555..17426 Mycoplasma genitalium G37 875485 NP_072675.1 CDS MG_015 NC_000908.2 17473 19242 D identified by sequence similarity; ABC transporter ATP-binding protein/permease 17473..19242 Mycoplasma genitalium G37 875229 NP_072678.2 CDS MG_018 NC_000908.2 19252 22347 D identified by sequence similarity; SNF2 family helicase 19252..22347 Mycoplasma genitalium G37 875220 NP_072679.1 CDS dnaJ NC_000908.2 22389 23558 D identified by sequence similarity; chaperone protein DnaJ 22389..23558 Mycoplasma genitalium G37 875219 NP_072680.1 CDS pip NC_000908.2 23542 24468 D identified by sequence similarity; proline iminopeptidase 23542..24468 Mycoplasma genitalium G37 875529 NP_072681.1 CDS metS NC_000908.2 24468 26006 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 24468..26006 Mycoplasma genitalium G37 875451 NP_072682.1 CDS rpoE NC_000908.2 26036 26473 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 26036..26473 Mycoplasma genitalium G37 875707 NP_072683.1 CDS fba NC_000908.2 26479 27345 D identified by sequence similarity; fructose-1,6-bisphosphate aldolase, class II 26479..27345 Mycoplasma genitalium G37 875427 NP_072684.1 CDS MG_024 NC_000908.2 27346 28449 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 27346..28449 Mycoplasma genitalium G37 875434 NP_072685.1 CDS MG_025 NC_000908.2 28652 29548 D identified by sequence similarity; glycosyl transferase, group 2 family protein 28652..29548 Mycoplasma genitalium G37 875281 NP_072686.1 CDS efp NC_000908.2 29552 30124 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 29552..30124 Mycoplasma genitalium G37 875394 NP_072687.1 CDS MG_027 NC_000908.2 30093 30548 D identified by sequence similarity; transcription termination/antitermination protein NusB 30093..30548 Mycoplasma genitalium G37 875575 NP_072688.1 CDS MG_028 NC_000908.2 30548 31153 D identified by sequence similarity; hypothetical protein 30548..31153 Mycoplasma genitalium G37 875284 NP_072689.1 CDS MG_029 NC_000908.2 31143 31703 R identified by sequence similarity; DJ-1/PfpI family protein complement(31143..31703) Mycoplasma genitalium G37 875348 NP_072690.1 CDS upp NC_000908.2 31705 32325 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(31705..32325) Mycoplasma genitalium G37 875326 NP_072691.1 CDS polC NC_000908.2 32359 36714 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC complement(32359..36714) Mycoplasma genitalium G37 875300 NP_072692.1 CDS MG_032 NC_000908.2 36977 38977 D identified by sequence similarity; hypothetical protein 36977..38977 Mycoplasma genitalium G37 875445 NP_072693.1 CDS glpF NC_000908.2 39127 39903 D identified by sequence similarity; glycerol uptake facilitator 39127..39903 Mycoplasma genitalium G37 875476 NP_072694.1 CDS tdk NC_000908.2 39872 40513 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(39872..40513) Mycoplasma genitalium G37 875417 NP_072695.1 CDS hisS NC_000908.2 40542 41786 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 40542..41786 Mycoplasma genitalium G37 875525 NP_072696.1 CDS aspS NC_000908.2 41776 43428 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 41776..43428 Mycoplasma genitalium G37 875228 NP_072697.1 CDS MG_037 NC_000908.2 43401 44753 D identified by sequence similarity; nicotinate phosphoribosyltransferase 43401..44753 Mycoplasma genitalium G37 875280 NP_072698.1 CDS glpK NC_000908.2 44750 46276 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(44750..46276) Mycoplasma genitalium G37 875413 NP_072699.1 CDS MG_039 NC_000908.2 46267 47421 R identified by sequence similarity; FAD-dependent glycerol-3-phosphate dehydrogenase complement(46267..47421) Mycoplasma genitalium G37 875455 NP_072700.1 CDS MG_040 NC_000908.2 47580 49355 D identified by sequence similarity; lipoprotein 47580..49355 Mycoplasma genitalium G37 875216 NP_072701.1 CDS ptsH NC_000908.2 49376 49642 D identified by sequence similarity; phosphocarrier protein HPr 49376..49642 Mycoplasma genitalium G37 875493 NP_072702.1 CDS potA NC_000908.2 49840 51519 D identified by sequence similarity; spermidine/putrescine ABC transporter ATP-binding protein 49840..51519 Mycoplasma genitalium G37 875517 NP_072703.1 CDS potB NC_000908.2 51524 52381 D identified by sequence similarity; spermidine/putrescine ABC transporter permease 51524..52381 Mycoplasma genitalium G37 875492 NP_072704.1 CDS potC NC_000908.2 52365 53219 D identified by sequence similarity; spermidine/putrescine ABC transporter permease 52365..53219 Mycoplasma genitalium G37 875282 NP_072705.1 CDS MG_045 NC_000908.2 53204 54655 D identified by sequence similarity; spermidine/putrescine ABC transporter spermidine/putrescine binding protein 53204..54655 Mycoplasma genitalium G37 875537 NP_072706.1 CDS MG_046 NC_000908.2 54657 55604 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 54657..55604 Mycoplasma genitalium G37 875433 NP_072707.1 CDS metX NC_000908.2 55588 56739 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 55588..56739 Mycoplasma genitalium G37 875239 NP_072708.1 CDS ffh NC_000908.2 56969 58309 R identified by sequence similarity; signal recognition particle protein complement(56969..58309) Mycoplasma genitalium G37 875253 NP_072709.2 CDS deoD NC_000908.2 58362 59078 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 58362..59078 Mycoplasma genitalium G37 875267 NP_072710.1 CDS MG_050 NC_000908.2 59082 59753 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 59082..59753 Mycoplasma genitalium G37 875446 NP_072711.1 CDS deoA NC_000908.2 59740 61005 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 59740..61005 Mycoplasma genitalium G37 875553 NP_072712.1 CDS cdd NC_000908.2 61014 61406 D identified by sequence similarity; cytidine deaminase 61014..61406 Mycoplasma genitalium G37 875728 NP_072713.1 CDS manB NC_000908.2 61406 63058 D identified by sequence similarity; phosphoglucomutase/phosphomannomutase 61406..63058 Mycoplasma genitalium G37 875706 NP_072714.1 CDS MG_054 NC_000908.2 63035 63985 R identified by sequence similarity; transcription antitermination protein NusG complement(63035..63985) Mycoplasma genitalium G37 875697 NP_072715.1 CDS secE NC_000908.2 63989 64360 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(63989..64360) Mycoplasma genitalium G37 875717 NP_072716.1 CDS rpmG NC_000908.2 64367 64513 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 complement(64367..64513) Mycoplasma genitalium G37 875514 NP_072717.1 CDS MG_474 NC_000908.2 64527 64910 R identified by sequence similarity; hypothetical protein complement(64527..64910) Mycoplasma genitalium G37 875730 NP_072718.1 CDS MG_056 NC_000908.2 64897 65730 R identified by sequence similarity; tetrapyrrole (corrin/porphyrin) methylase protein complement(64897..65730) Mycoplasma genitalium G37 875528 NP_072719.1 CDS MG_057 NC_000908.2 65712 66248 R identified by sequence similarity; small primase-like protein complement(65712..66248) Mycoplasma genitalium G37 875232 NP_072720.2 CDS prs NC_000908.2 66227 67225 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(66227..67225) Mycoplasma genitalium G37 875549 NP_072721.1 CDS smpB NC_000908.2 67206 67643 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(67206..67643) Mycoplasma genitalium G37 875214 NP_072722.1 CDS MG_060 NC_000908.2 67650 68543 D identified by sequence similarity; glycosyl transferase, group 2 family protein 67650..68543 Mycoplasma genitalium G37 875700 NP_072723.2 CDS MG_061 NC_000908.2 68522 70225 R identified by sequence similarity; MFS family transporter complement(68522..70225) Mycoplasma genitalium G37 875699 NP_072724.1 CDS fruA NC_000908.2 70530 72572 D identified by sequence similarity; PTS system, fructose-specific IIABC component 70530..72572 Mycoplasma genitalium G37 875519 NP_072725.2 CDS fruK NC_000908.2 72523 73434 D identified by sequence similarity; 1-phosphofructokinase 72523..73434 Mycoplasma genitalium G37 875512 NP_072726.1 CDS MG_064 NC_000908.2 73690 77685 D identified by sequence similarity; ABC transporter permease 73690..77685 Mycoplasma genitalium G37 875463 NP_072727.1 CDS MG_065 NC_000908.2 77685 79085 D identified by sequence similarity; ABC transporter ATP-binding protein 77685..79085 Mycoplasma genitalium G37 875526 NP_072728.1 CDS tktA NC_000908.2 79089 81035 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 79089..81035 Mycoplasma genitalium G37 875474 NP_072729.1 CDS MG_067 NC_000908.2 81046 82596 D identified by sequence similarity; lipoprotein 81046..82596 Mycoplasma genitalium G37 875456 NP_072730.1 CDS MG_068 NC_000908.2 82620 84044 D identified by sequence similarity; lipoprotein 82620..84044 Mycoplasma genitalium G37 875504 NP_072731.1 CDS ptsG NC_000908.2 88228 90954 D identified by sequence similarity; PTS system, glucose-specific IIABC component 88228..90954 Mycoplasma genitalium G37 875466 NP_072732.1 CDS rpsB NC_000908.2 91065 91919 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 91065..91919 Mycoplasma genitalium G37 875215 NP_072733.1 CDS MG_071 NC_000908.2 91924 94548 D identified by sequence similarity; ATPase P 91924..94548 Mycoplasma genitalium G37 875508 NP_072734.1 CDS secA NC_000908.2 94535 96955 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 94535..96955 Mycoplasma genitalium G37 875509 NP_072735.1 CDS uvrB NC_000908.2 96933 98903 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 96933..98903 Mycoplasma genitalium G37 875513 NP_072736.1 CDS MG_074 NC_000908.2 98906 99319 D identified by sequence similarity; hypothetical protein 98906..99319 Mycoplasma genitalium G37 875254 NP_072737.1 CDS MG_075 NC_000908.2 99383 102457 D identified by sequence similarity; hypothetical protein 99383..102457 Mycoplasma genitalium G37 875465 NP_072738.1 CDS MG_076 NC_000908.2 102454 102870 R identified by sequence similarity; hypothetical protein complement(102454..102870) Mycoplasma genitalium G37 875486 NP_072739.1 CDS oppB NC_000908.2 103104 104327 D identified by sequence similarity; peptide ABC transporter permease 103104..104327 Mycoplasma genitalium G37 875499 NP_072740.1 CDS oppC NC_000908.2 104320 105450 D identified by sequence similarity; peptide ABC transporter permease 104320..105450 Mycoplasma genitalium G37 875226 NP_072741.1 CDS oppD NC_000908.2 105452 106660 D identified by sequence similarity; peptide ABC transporter ATP-binding protein 105452..106660 Mycoplasma genitalium G37 875715 NP_072742.1 CDS oppF NC_000908.2 106660 109206 D identified by sequence similarity; peptide ABC transporter ATP-binding protein 106660..109206 Mycoplasma genitalium G37 875732 NP_072743.1 CDS rplK NC_000908.2 109262 109675 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 109262..109675 Mycoplasma genitalium G37 875687 NP_072744.1 CDS rplA NC_000908.2 109675 110355 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 109675..110355 Mycoplasma genitalium G37 875701 NP_072745.1 CDS pth NC_000908.2 110355 110924 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 110355..110924 Mycoplasma genitalium G37 875723 NP_072746.1 CDS MG_084 NC_000908.2 110917 111789 D identified by sequence similarity; tRNA(Ile)-lysidine synthetase 110917..111789 Mycoplasma genitalium G37 875283 NP_072747.1 CDS ser NC_000908.2 111790 112725 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 111790..112725 Mycoplasma genitalium G37 875285 NP_072748.1 CDS lgt NC_000908.2 112718 113866 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 112718..113866 Mycoplasma genitalium G37 875464 NP_072749.1 CDS rpsL NC_000908.2 113895 114314 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 113895..114314 Mycoplasma genitalium G37 875483 NP_072750.1 CDS rpS7 NC_000908.2 114331 114798 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 114331..114798 Mycoplasma genitalium G37 875447 NP_072751.1 CDS fus NC_000908.2 114808 116874 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 114808..116874 Mycoplasma genitalium G37 875260 NP_072752.1 CDS rpsF NC_000908.2 116926 117552 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 116926..117552 Mycoplasma genitalium G37 875432 NP_072753.1 CDS ssb NC_000908.2 117553 118035 D identified by sequence similarity; single-strand binding protein family 117553..118035 Mycoplasma genitalium G37 875527 NP_072754.1 CDS rpsR NC_000908.2 118025 118342 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 118025..118342 Mycoplasma genitalium G37 875438 NP_072755.1 CDS rplI NC_000908.2 118345 118797 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 118345..118797 Mycoplasma genitalium G37 875264 NP_072756.2 CDS dnaB NC_000908.2 118781 120187 D identified by sequence similarity; replicative DNA helicase 118781..120187 Mycoplasma genitalium G37 875532 NP_072757.1 CDS MG_095 NC_000908.2 120191 121387 D identified by sequence similarity; lipoprotein 120191..121387 Mycoplasma genitalium G37 875422 NP_072758.1 CDS MG_096 NC_000908.2 121571 123523 D identified by sequence similarity; hypothetical protein 121571..123523 Mycoplasma genitalium G37 875725 NP_072759.1 CDS ung NC_000908.2 123580 124317 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 123580..124317 Mycoplasma genitalium G37 875721 NP_072760.1 CDS MG_098 NC_000908.2 124417 125850 D contains unknown domain at the N-terminus that is found by itself in some proteins by in others is fused to GatC at the C-terminus; aspartyl/glutamyl-tRNA amidotransferase subunit C 124417..125850 Mycoplasma genitalium G37 875690 NP_072761.1 CDS gatA NC_000908.2 125853 127286 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 125853..127286 Mycoplasma genitalium G37 875261 NP_072762.1 CDS gatB NC_000908.2 127279 128712 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 127279..128712 Mycoplasma genitalium G37 875247 NP_072763.1 CDS MG_101 NC_000908.2 128687 129355 D identified by sequence similarity; hypothetical protein 128687..129355 Mycoplasma genitalium G37 875406 NP_072764.1 CDS trxB NC_000908.2 129348 130295 D identified by sequence similarity; thioredoxin-disulfide reductase 129348..130295 Mycoplasma genitalium G37 875416 NP_072765.1 CDS MG_103 NC_000908.2 130285 131127 D identified by sequence similarity; hypothetical protein 130285..131127 Mycoplasma genitalium G37 875251 YP_654151.1 CDS secG NC_000908.2 131149 131382 D preprotein translocase subunit SecG 131149..131382 Mycoplasma genitalium G37 4126687 NP_072766.1 CDS vacB NC_000908.2 131385 133562 D identified by sequence similarity; ribonuclease R 131385..133562 Mycoplasma genitalium G37 875442 NP_072767.2 CDS MG_105 NC_000908.2 133570 134172 D identified by sequence similarity; hypothetical protein 133570..134172 Mycoplasma genitalium G37 875469 NP_072768.2 CDS def NC_000908.2 134147 134728 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(134147..134728) Mycoplasma genitalium G37 875270 NP_072769.1 CDS gmk NC_000908.2 134769 135338 D identified by sequence similarity; guanylate kinase 134769..135338 Mycoplasma genitalium G37 875249 NP_072770.1 CDS MG_108 NC_000908.2 135338 136120 D identified by sequence similarity; protein phosphatase 2C 135338..136120 Mycoplasma genitalium G37 875507 NP_072771.2 CDS MG_109 NC_000908.2 136105 137268 D identified by sequence similarity; serine/threonine protein kinase 136105..137268 Mycoplasma genitalium G37 875289 NP_072772.1 CDS MG_110 NC_000908.2 137255 138091 D identified by sequence similarity; ribosome small subunit-dependent GTPase A 137255..138091 Mycoplasma genitalium G37 875411 NP_072773.2 CDS pgi NC_000908.2 138112 139407 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 138112..139407 Mycoplasma genitalium G37 875452 NP_072774.1 CDS MG_112 NC_000908.2 139397 140026 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 139397..140026 Mycoplasma genitalium G37 875550 NP_072775.1 CDS asnC NC_000908.2 140040 141410 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 140040..141410 Mycoplasma genitalium G37 875695 NP_072776.1 CDS pgsA NC_000908.2 141346 142056 D identified by sequence similarity; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 141346..142056 Mycoplasma genitalium G37 875551 NP_072777.1 CDS MG_115 NC_000908.2 142081 142554 D identified by sequence similarity; competence/damage inducible protein CinA 142081..142554 Mycoplasma genitalium G37 875498 NP_072778.1 CDS MG_116 NC_000908.2 142563 143318 D identified by sequence similarity; hypothetical protein 142563..143318 Mycoplasma genitalium G37 875546 NP_072779.1 CDS MG_117 NC_000908.2 143311 143955 D identified by sequence similarity; hypothetical protein 143311..143955 Mycoplasma genitalium G37 875547 NP_072780.1 CDS galE NC_000908.2 143936 144958 D identified by sequence similarity; UDP-glucose 4-epimerase 143936..144958 Mycoplasma genitalium G37 875535 NP_072781.1 CDS mglA NC_000908.2 144973 146667 D identified by sequence similarity; ABC transporter ATP-binding protein 144973..146667 Mycoplasma genitalium G37 875548 NP_072782.1 CDS MG_120 NC_000908.2 146674 148236 D identified by sequence similarity; ABC transporter permease 146674..148236 Mycoplasma genitalium G37 875541 NP_072783.1 CDS MG_121 NC_000908.2 148239 149159 D identified by sequence similarity; ABC transporter permease 148239..149159 Mycoplasma genitalium G37 875709 NP_072784.1 CDS topA NC_000908.2 149199 151328 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 149199..151328 Mycoplasma genitalium G37 875227 NP_072785.1 CDS MG_123 NC_000908.2 151306 152721 D identified by sequence similarity; hypothetical protein 151306..152721 Mycoplasma genitalium G37 875408 NP_072786.1 CDS trxA NC_000908.2 152768 153076 D identified by sequence similarity; thioredoxin 152768..153076 Mycoplasma genitalium G37 875225 NP_072787.1 CDS MG_125 NC_000908.2 153082 153939 D identified by sequence similarity; Cof-like hydrolase 153082..153939 Mycoplasma genitalium G37 875402 NP_072788.1 CDS trpS NC_000908.2 153920 154963 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(153920..154963) Mycoplasma genitalium G37 875379 NP_072789.1 CDS MG_127 NC_000908.2 154999 155436 D identified by sequence similarity; Spx subfamily protein 154999..155436 Mycoplasma genitalium G37 875375 NP_072790.1 CDS ppnK NC_000908.2 155444 156223 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 155444..156223 Mycoplasma genitalium G37 875342 NP_072791.1 CDS MG_129 NC_000908.2 156223 156576 D identified by sequence similarity; hypothetical protein 156223..156576 Mycoplasma genitalium G37 875287 NP_072792.1 CDS MG_130 NC_000908.2 156566 158020 D identified by sequence similarity; hypothetical protein 156566..158020 Mycoplasma genitalium G37 875274 NP_072794.1 CDS MG_132 NC_000908.2 158581 159006 R identified by sequence similarity; HIT domain-containing protein complement(158581..159006) Mycoplasma genitalium G37 875581 NP_072795.2 CDS MG_133 NC_000908.2 158984 159778 R identified by sequence similarity; hypothetical protein complement(158984..159778) Mycoplasma genitalium G37 875277 NP_072796.1 CDS MG_134 NC_000908.2 159798 160100 D identified by sequence similarity; hypothetical protein 159798..160100 Mycoplasma genitalium G37 875231 NP_072797.1 CDS MG_135 NC_000908.2 160072 160914 R identified by sequence similarity; hypothetical protein complement(160072..160914) Mycoplasma genitalium G37 875722 NP_072798.1 CDS lysS NC_000908.2 160963 162435 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 160963..162435 Mycoplasma genitalium G37 875448 NP_072799.1 CDS glf NC_000908.2 162377 163591 D identified by sequence similarity; UDP-galactopyranose mutase 162377..163591 Mycoplasma genitalium G37 875453 NP_072800.1 CDS lepA NC_000908.2 163591 165387 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 163591..165387 Mycoplasma genitalium G37 875539 NP_072801.1 CDS MG_139 NC_000908.2 165471 167180 D identified by sequence similarity; metallo-beta-lactamase superfamily protein 165471..167180 Mycoplasma genitalium G37 875237 NP_072802.1 CDS MG_140 NC_000908.2 175805 179146 D identified by sequence similarity; hypothetical protein 175805..179146 Mycoplasma genitalium G37 875533 NP_072803.1 CDS nusA NC_000908.2 179151 180746 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 179151..180746 Mycoplasma genitalium G37 875500 YP_654152.1 CDS MG_477 NC_000908.2 180746 181018 D hypothetical protein 180746..181018 Mycoplasma genitalium G37 4126688 NP_072804.1 CDS infB NC_000908.2 181005 182864 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 181005..182864 Mycoplasma genitalium G37 875480 NP_072805.1 CDS MG_143 NC_000908.2 182851 183189 D identified by sequence similarity; ribosome-binding factor A 182851..183189 Mycoplasma genitalium G37 875468 NP_072806.1 CDS MG_144 NC_000908.2 183214 184053 D identified by sequence similarity; hypothetical protein 183214..184053 Mycoplasma genitalium G37 875217 NP_072807.1 CDS MG_145 NC_000908.2 184053 184862 D identified by sequence similarity; riboflavin biosynthesis protein RibF 184053..184862 Mycoplasma genitalium G37 875524 NP_072808.1 CDS MG_146 NC_000908.2 184875 186149 D identified by sequence similarity; hypothetical protein 184875..186149 Mycoplasma genitalium G37 875520 NP_072809.2 CDS MG_147 NC_000908.2 186136 187263 D identified by sequence similarity; hypothetical protein 186136..187263 Mycoplasma genitalium G37 875472 NP_072810.1 CDS MG_148 NC_000908.2 187302 188531 D identified by sequence similarity; hypothetical protein 187302..188531 Mycoplasma genitalium G37 875475 NP_072811.1 CDS MG_149 NC_000908.2 188607 189452 D identified by sequence similarity; lipoprotein 188607..189452 Mycoplasma genitalium G37 875240 NP_072812.2 CDS MG_478 NC_000908.2 189492 189956 D identified by sequence similarity; hypothetical protein 189492..189956 Mycoplasma genitalium G37 875467 NP_072813.1 CDS rpsJ NC_000908.2 190046 190366 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 190046..190366 Mycoplasma genitalium G37 875470 NP_072814.1 CDS rplC NC_000908.2 190370 191143 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 190370..191143 Mycoplasma genitalium G37 875552 NP_072815.1 CDS rplD NC_000908.2 191143 191778 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 191143..191778 Mycoplasma genitalium G37 875518 NP_072816.1 CDS rplW NC_000908.2 191782 192102 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 191782..192102 Mycoplasma genitalium G37 875471 NP_072817.1 CDS rplB NC_000908.2 192102 192959 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 192102..192959 Mycoplasma genitalium G37 875534 NP_072818.1 CDS rpsS NC_000908.2 192959 193222 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 192959..193222 Mycoplasma genitalium G37 875544 NP_072819.1 CDS rplV NC_000908.2 193225 193659 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 193225..193659 Mycoplasma genitalium G37 875460 NP_072820.1 CDS rpsC NC_000908.2 193662 194468 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 193662..194468 Mycoplasma genitalium G37 875444 NP_072821.1 CDS rplP NC_000908.2 194474 194890 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 194474..194890 Mycoplasma genitalium G37 875503 NP_072822.1 CDS rpmC NC_000908.2 194890 195492 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 194890..195492 Mycoplasma genitalium G37 875418 NP_072823.1 CDS rpsQ NC_000908.2 195492 195749 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 195492..195749 Mycoplasma genitalium G37 875275 NP_072824.1 CDS rplN NC_000908.2 195753 196121 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 195753..196121 Mycoplasma genitalium G37 875685 NP_072825.1 CDS rplX NC_000908.2 196121 196447 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 196121..196447 Mycoplasma genitalium G37 875711 NP_072826.1 CDS rplE NC_000908.2 196453 196995 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 196453..196995 Mycoplasma genitalium G37 875230 NP_072827.1 CDS rpsN NC_000908.2 196998 197183 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 196998..197183 Mycoplasma genitalium G37 875554 NP_072828.1 CDS rpsH NC_000908.2 197177 197602 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 197177..197602 Mycoplasma genitalium G37 875692 NP_072829.1 CDS rplF NC_000908.2 197609 198163 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 197609..198163 Mycoplasma genitalium G37 875542 NP_072830.1 CDS rplR NC_000908.2 198165 198512 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 198165..198512 Mycoplasma genitalium G37 875718 NP_072831.1 CDS rpsE NC_000908.2 198517 199152 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 198517..199152 Mycoplasma genitalium G37 875256 NP_072832.1 CDS rplO NC_000908.2 199158 199610 D late assembly protein; 50S ribosomal protein L15 199158..199610 Mycoplasma genitalium G37 875570 NP_072833.1 CDS secY NC_000908.2 199610 201037 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 199610..201037 Mycoplasma genitalium G37 875393 NP_072834.1 CDS adk NC_000908.2 201031 201675 D identified by sequence similarity; adenylate kinase 201031..201675 Mycoplasma genitalium G37 875540 NP_072835.1 CDS map NC_000908.2 201678 202424 D identified by sequence similarity; methionine aminopeptidase, type I 201678..202424 Mycoplasma genitalium G37 875255 NP_072836.1 CDS infA NC_000908.2 202424 202636 D identified by sequence similarity; translation initiation factor IF-1 202424..202636 Mycoplasma genitalium G37 875265 NP_072837.1 CDS rpmJ NC_000908.2 202647 202760 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 202647..202760 Mycoplasma genitalium G37 875341 NP_072838.1 CDS rpsM NC_000908.2 202760 203134 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 202760..203134 Mycoplasma genitalium G37 875378 NP_072839.2 CDS rpS11 NC_000908.2 203134 203499 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 203134..203499 Mycoplasma genitalium G37 875401 NP_072840.1 CDS rpoA NC_000908.2 203515 204501 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 203515..204501 Mycoplasma genitalium G37 875383 NP_072841.1 CDS rplQ NC_000908.2 204514 204885 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 204514..204885 Mycoplasma genitalium G37 875431 NP_072842.1 CDS cbiO NC_000908.2 204872 205696 D with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 204872..205696 Mycoplasma genitalium G37 875266 NP_072843.1 CDS cbiO NC_000908.2 205681 206595 D with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 205681..206595 Mycoplasma genitalium G37 875238 NP_072844.1 CDS MG_181 NC_000908.2 206588 207850 D identified by sequence similarity; metal ABC transporter permease 206588..207850 Mycoplasma genitalium G37 875530 NP_072845.1 CDS truA NC_000908.2 207843 208577 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 207843..208577 Mycoplasma genitalium G37 875727 NP_072846.1 CDS pepF NC_000908.2 208567 210390 D identified by sequence similarity; oligoendopeptidase F 208567..210390 Mycoplasma genitalium G37 875531 NP_072847.1 CDS MG_184 NC_000908.2 210391 211344 D identified by sequence similarity; adenine-specific DNA modification methylase 210391..211344 Mycoplasma genitalium G37 875719 NP_072848.1 CDS MG_185 NC_000908.2 211444 213549 D identified by sequence similarity; lipoprotein 211444..213549 Mycoplasma genitalium G37 875234 NP_072849.1 CDS MG_186 NC_000908.2 216016 216768 D identified by sequence similarity; nuclease-like protein 216016..216768 Mycoplasma genitalium G37 875720 NP_072850.1 CDS MG_187 NC_000908.2 216761 218518 D identified by sequence similarity; ABC transporter ATP-binding protein 216761..218518 Mycoplasma genitalium G37 875286 NP_072851.1 CDS MG_188 NC_000908.2 218521 219510 D identified by sequence similarity; ABC transporter permease 218521..219510 Mycoplasma genitalium G37 875538 NP_072852.2 CDS MG_189 NC_000908.2 219482 220438 D identified by sequence similarity; ABC transporter permease 219482..220438 Mycoplasma genitalium G37 875233 NP_072853.2 CDS mgpA NC_000908.2 220607 221563 D identified by sequence similarity; DHH family phosphoesterase 220607..221563 Mycoplasma genitalium G37 875410 NP_072854.1 CDS mgpB NC_000908.2 221570 225904 D identified by sequence similarity; MgPa adhesin 221570..225904 Mycoplasma genitalium G37 875543 NP_072855.2 CDS mgpC NC_000908.2 225906 229067 D identified by sequence similarity; hypothetical protein 225906..229067 Mycoplasma genitalium G37 875288 NP_072856.1 CDS pheS NC_000908.2 232009 233034 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 232009..233034 Mycoplasma genitalium G37 875437 NP_072857.1 CDS pheT NC_000908.2 233038 235458 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 233038..235458 Mycoplasma genitalium G37 875729 NP_072858.1 CDS infC NC_000908.2 235517 236062 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 235517..236062 Mycoplasma genitalium G37 875698 NP_072859.1 CDS rpmI NC_000908.2 236065 236244 D identified by sequence similarity; 50S ribosomal protein L35 236065..236244 Mycoplasma genitalium G37 875484 NP_072860.1 CDS rplT NC_000908.2 236247 236621 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 236247..236621 Mycoplasma genitalium G37 875430 NP_072862.1 CDS MG_200 NC_000908.2 237347 239152 D identified by sequence similarity; DnaJ domain-containing protein 237347..239152 Mycoplasma genitalium G37 875694 NP_072863.1 CDS grpE NC_000908.2 239164 239817 D identified by sequence similarity; co-chaperone GrpE 239164..239817 Mycoplasma genitalium G37 875689 NP_072864.1 CDS MG_202 NC_000908.2 239827 240195 D identified by sequence similarity; hypothetical protein 239827..240195 Mycoplasma genitalium G37 875691 NP_072865.1 CDS parE NC_000908.2 240323 242224 D identified by sequence similarity; DNA topoisomerase IV, B subunit 240323..242224 Mycoplasma genitalium G37 875693 NP_072866.1 CDS parC NC_000908.2 242224 244569 D identified by sequence similarity; DNA topoisomerase IV, A subunit 242224..244569 Mycoplasma genitalium G37 875340 NP_072867.1 CDS hrcA NC_000908.2 244566 245597 R Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor complement(244566..245597) Mycoplasma genitalium G37 875407 NP_072868.1 CDS uvrC NC_000908.2 245633 247426 D identified by sequence similarity; excinuclease ABC, C subunit 245633..247426 Mycoplasma genitalium G37 875724 NP_072869.1 CDS MG_207 NC_000908.2 247407 247910 D identified by sequence similarity; serine/threonine protein phosphatase 247407..247910 Mycoplasma genitalium G37 875395 NP_072870.1 CDS MG_208 NC_000908.2 247903 248493 R identified by sequence similarity; glycoprotease complement(247903..248493) Mycoplasma genitalium G37 875397 NP_072871.1 CDS MG_209 NC_000908.2 248477 249403 R identified by sequence similarity; RluA family pseudouridine synthase complement(248477..249403) Mycoplasma genitalium G37 875377 NP_072872.1 CDS lspA NC_000908.2 249403 249948 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; signal peptidase II complement(249403..249948) Mycoplasma genitalium G37 875392 NP_072873.1 CDS MG_480 NC_000908.2 250149 250808 D identified by sequence similarity; hypothetical protein 250149..250808 Mycoplasma genitalium G37 875712 NP_072874.1 CDS rpsU NC_000908.2 250808 250996 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 250808..250996 Mycoplasma genitalium G37 875583 NP_072875.1 CDS MG_211 NC_000908.2 250998 251441 D identified by sequence similarity; hypothetical protein 250998..251441 Mycoplasma genitalium G37 875335 NP_072876.1 CDS acpS NC_000908.2 251444 251788 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 251444..251788 Mycoplasma genitalium G37 875324 NP_072877.1 CDS plsC NC_000908.2 251781 252587 D identified by sequence similarity; 1-acyl-sn-glycerol-3-phosphate acyltransferase 251781..252587 Mycoplasma genitalium G37 875333 NP_072878.1 CDS scpA NC_000908.2 252580 253995 D functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 252580..253995 Mycoplasma genitalium G37 875334 NP_072879.1 CDS scpB NC_000908.2 253979 254602 D functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 253979..254602 Mycoplasma genitalium G37 875337 NP_072880.1 CDS pfkA NC_000908.2 254621 255592 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 254621..255592 Mycoplasma genitalium G37 875293 NP_072881.1 CDS pyk NC_000908.2 255595 257121 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 255595..257121 Mycoplasma genitalium G37 875390 NP_072882.1 CDS MG_217 NC_000908.2 258041 259159 D identified by sequence similarity; proline-rich P65 protein 258041..259159 Mycoplasma genitalium G37 875361 NP_072883.1 CDS hmw2 NC_000908.2 259177 264594 D identified by sequence similarity; HMW2 cytadherence accessory protein 259177..264594 Mycoplasma genitalium G37 875360 NP_072884.1 CDS MG_491 NC_000908.2 264597 265637 D identified by sequence similarity; hypothetical protein 264597..265637 Mycoplasma genitalium G37 875359 NP_072885.1 CDS MG_219 NC_000908.2 265597 266043 D hypothetical protein; identified by GeneMark; hypothetical protein 265597..266043 Mycoplasma genitalium G37 875358 NP_072886.2 CDS MG_220 NC_000908.2 266075 266356 R identified by sequence similarity; hypothetical protein complement(266075..266356) Mycoplasma genitalium G37 875357 NP_072887.2 CDS MG_221 NC_000908.2 266666 267091 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 266666..267091 Mycoplasma genitalium G37 875318 NP_072888.1 CDS mraW NC_000908.2 267081 268010 D identified by sequence similarity; S-adenosyl-methyltransferase MraW 267081..268010 Mycoplasma genitalium G37 875317 NP_072889.1 CDS MG_223 NC_000908.2 268012 269247 D identified by sequence similarity; hypothetical protein 268012..269247 Mycoplasma genitalium G37 875316 NP_072890.1 CDS ftsZ NC_000908.2 269250 270359 D identified by sequence similarity; cell division protein FtsZ 269250..270359 Mycoplasma genitalium G37 875315 NP_072891.1 CDS MG_225 NC_000908.2 270405 271874 D identified by sequence similarity; amino acid-polyamine-organocation (APC) permease family protein 270405..271874 Mycoplasma genitalium G37 875314 NP_072892.2 CDS MG_226 NC_000908.2 271840 273318 D identified by sequence similarity; amino acid-polyamine-organocation (APC) permease family protein 271840..273318 Mycoplasma genitalium G37 875313 NP_072893.1 CDS thyA NC_000908.2 273790 274653 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 273790..274653 Mycoplasma genitalium G37 875312 NP_072894.1 CDS dhfR NC_000908.2 274653 275135 D identified by sequence similarity; dihydrofolate reductase 274653..275135 Mycoplasma genitalium G37 875311 NP_072895.1 CDS nrdF NC_000908.2 275141 276163 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 275141..276163 Mycoplasma genitalium G37 875310 NP_072896.1 CDS nrdI NC_000908.2 276167 276628 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 276167..276628 Mycoplasma genitalium G37 875309 NP_072897.1 CDS nrdE NC_000908.2 276647 278812 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 276647..278812 Mycoplasma genitalium G37 875308 NP_072898.1 CDS rplU NC_000908.2 278905 279207 D identified by sequence similarity; 50S ribosomal protein L21 278905..279207 Mycoplasma genitalium G37 875299 NP_072899.1 CDS MG_233 NC_000908.2 279200 279499 D identified by sequence similarity; hypothetical protein 279200..279499 Mycoplasma genitalium G37 875298 NP_072900.1 CDS rpmA NC_000908.2 279492 279806 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 279492..279806 Mycoplasma genitalium G37 875297 NP_072901.1 CDS MG_235 NC_000908.2 279799 280674 D identified by sequence similarity; apurinic endonuclease (APN1) 279799..280674 Mycoplasma genitalium G37 875296 NP_072902.1 CDS MG_236 NC_000908.2 280664 281086 D identified by sequence similarity; hypothetical protein 280664..281086 Mycoplasma genitalium G37 875374 NP_072903.1 CDS MG_237 NC_000908.2 281079 281963 D identified by sequence similarity; hypothetical protein 281079..281963 Mycoplasma genitalium G37 875373 NP_072904.1 CDS tig NC_000908.2 281993 283327 D identified by sequence similarity; trigger factor 281993..283327 Mycoplasma genitalium G37 875304 NP_072905.1 CDS lon NC_000908.2 283396 285783 D identified by sequence similarity; ATP-dependent protease La 283396..285783 Mycoplasma genitalium G37 875303 NP_072906.2 CDS nadD NC_000908.2 285780 286832 R catalyzes the reversible adenylation of nicotinate mononucleotide to nicotinic acid adenine dinucleotide; nicotinate-nucleotide adenylyltransferase complement(285780..286832) Mycoplasma genitalium G37 875302 NP_072907.1 CDS MG_241 NC_000908.2 286885 288747 D identified by sequence similarity; hypothetical protein 286885..288747 Mycoplasma genitalium G37 875301 NP_072908.1 CDS MG_242 NC_000908.2 288753 290645 D identified by sequence similarity; hypothetical protein 288753..290645 Mycoplasma genitalium G37 875372 NP_072909.1 CDS MG_244 NC_000908.2 291334 293445 D identified by sequence similarity; UvrD/REP helicase 291334..293445 Mycoplasma genitalium G37 875370 NP_072910.1 CDS MG_245 NC_000908.2 293448 293945 D identified by sequence similarity; 5-formyltetrahydrofolate cyclo-ligase 293448..293945 Mycoplasma genitalium G37 875369 NP_072911.1 CDS MG_246 NC_000908.2 293938 294783 D identified by sequence similarity; serine/threonine protein phosphatase 293938..294783 Mycoplasma genitalium G37 875368 NP_072912.1 CDS MG_247 NC_000908.2 294767 295486 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY complement(294767..295486) Mycoplasma genitalium G37 875367 NP_072913.1 CDS MG_248 NC_000908.2 295473 296129 R identified by sequence similarity; hypothetical protein complement(295473..296129) Mycoplasma genitalium G37 875322 NP_072914.1 CDS rpoD NC_000908.2 296113 297606 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor complement(296113..297606) Mycoplasma genitalium G37 875321 NP_072915.1 CDS dnaE NC_000908.2 297651 299474 R identified by sequence similarity; DNA primase complement(297651..299474) Mycoplasma genitalium G37 875320 NP_072916.1 CDS MG_251 NC_000908.2 299464 300804 R Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase complement(299464..300804) Mycoplasma genitalium G37 875319 NP_072917.1 CDS MG_252 NC_000908.2 300824 301552 R identified by sequence similarity; RNA methyltransferase complement(300824..301552) Mycoplasma genitalium G37 875332 NP_072918.1 CDS cysS NC_000908.2 301555 302841 R identified by sequence similarity; cysteinyl-tRNA synthetase complement(301555..302841) Mycoplasma genitalium G37 875331 NP_072919.1 CDS MG_254 NC_000908.2 302846 304825 R identified by sequence similarity; DNA ligase, NAD-dependent complement(302846..304825) Mycoplasma genitalium G37 875330 NP_072920.1 CDS MG_255 NC_000908.2 305001 306098 D identified by sequence similarity; hypothetical protein 305001..306098 Mycoplasma genitalium G37 875328 NP_072922.1 CDS MG_256 NC_000908.2 306821 307591 D identified by sequence similarity; hypothetical protein 306821..307591 Mycoplasma genitalium G37 875353 NP_072923.1 CDS rpmE NC_000908.2 307637 307930 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 307637..307930 Mycoplasma genitalium G37 875352 NP_072924.1 CDS prfA NC_000908.2 307930 309009 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 307930..309009 Mycoplasma genitalium G37 875351 NP_072925.1 CDS MG_259 NC_000908.2 309010 310380 D identified by sequence similarity; HemK family modification methylase 309010..310380 Mycoplasma genitalium G37 875350 NP_072926.1 CDS MG_260 NC_000908.2 310511 312808 D identified by sequence similarity; lipoprotein 310511..312808 Mycoplasma genitalium G37 875349 NP_072927.1 CDS polC-2 NC_000908.2 315701 318325 D identified by sequence similarity; DNA polymerase III subunit alpha 315701..318325 Mycoplasma genitalium G37 875381 NP_072928.1 CDS MG_262 NC_000908.2 318332 319207 D identified by sequence similarity; 5'-3' exonuclease 318332..319207 Mycoplasma genitalium G37 875380 NP_072929.1 CDS mutM NC_000908.2 319207 320061 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 319207..320061 Mycoplasma genitalium G37 875325 NP_072930.1 CDS MG_263 NC_000908.2 320177 321052 D identified by sequence similarity; Cof-like hydrolase 320177..321052 Mycoplasma genitalium G37 875307 NP_072931.1 CDS MG_264 NC_000908.2 321046 321642 D identified by sequence similarity; dephospho-CoA kinase 321046..321642 Mycoplasma genitalium G37 875306 NP_072932.1 CDS MG_265 NC_000908.2 321578 322414 R identified by sequence similarity; Cof-like hydrolase complement(321578..322414) Mycoplasma genitalium G37 875305 NP_072933.1 CDS leuS NC_000908.2 322433 324811 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(322433..324811) Mycoplasma genitalium G37 875347 NP_072934.1 CDS MG_267 NC_000908.2 324812 325159 R identified by sequence similarity; hypothetical protein complement(324812..325159) Mycoplasma genitalium G37 875343 NP_072935.1 CDS MG_268 NC_000908.2 325193 325879 R identified by sequence similarity; hypothetical protein complement(325193..325879) Mycoplasma genitalium G37 875387 NP_072936.1 CDS MG_269 NC_000908.2 326030 327052 R identified by sequence similarity; hypothetical protein complement(326030..327052) Mycoplasma genitalium G37 875386 NP_072937.1 CDS lplA NC_000908.2 327433 328443 R identified by sequence similarity; lipoyltransferase/lipoate-protein ligase complement(327433..328443) Mycoplasma genitalium G37 875385 NP_072938.1 CDS pdhD NC_000908.2 328454 329827 R identified by sequence similarity; dihydrolipoamide dehydrogenase complement(328454..329827) Mycoplasma genitalium G37 875384 NP_072939.1 CDS pdhC NC_000908.2 329831 330985 R Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 complement(329831..330985) Mycoplasma genitalium G37 875388 NP_072940.1 CDS pdhB NC_000908.2 331235 332215 R identified by sequence similarity; pyruvate dehydrogenase component E1, beta subunit complement(331235..332215) Mycoplasma genitalium G37 875399 NP_072941.1 CDS pdhA NC_000908.2 332233 333309 R identified by sequence similarity; pyruvate dehydrogenase component E1, alpha subunit complement(332233..333309) Mycoplasma genitalium G37 875404 NP_072942.2 CDS nox NC_000908.2 333337 334773 R identified by sequence similarity; NADH oxidase complement(333337..334773) Mycoplasma genitalium G37 875557 NP_072943.1 CDS MG_276 NC_000908.2 334856 335398 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(334856..335398) Mycoplasma genitalium G37 875405 NP_072944.1 CDS MG_277 NC_000908.2 335412 338324 R identified by sequence similarity; hypothetical protein complement(335412..338324) Mycoplasma genitalium G37 875243 NP_072945.1 CDS relA NC_000908.2 338367 340529 D identified by sequence similarity; GTP pyrophosphokinase 338367..340529 Mycoplasma genitalium G37 875246 NP_072946.1 CDS MG_279 NC_000908.2 340526 341182 R identified by sequence similarity; hypothetical protein complement(340526..341182) Mycoplasma genitalium G37 875248 NP_072947.2 CDS MG_280 NC_000908.2 341175 341972 R identified by sequence similarity; hypothetical protein complement(341175..341972) Mycoplasma genitalium G37 875257 NP_072948.1 CDS MG_281 NC_000908.2 342033 343703 R identified by sequence similarity; hypothetical protein complement(342033..343703) Mycoplasma genitalium G37 875235 NP_072949.1 CDS greA NC_000908.2 344365 344850 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(344365..344850) Mycoplasma genitalium G37 875338 NP_072950.1 CDS proS NC_000908.2 345182 346633 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 345182..346633 Mycoplasma genitalium G37 875489 NP_072951.1 CDS MG_284 NC_000908.2 346854 347252 D identified by sequence similarity; hypothetical protein 346854..347252 Mycoplasma genitalium G37 875733 NP_072952.1 CDS MG_285 NC_000908.2 347215 348258 D identified by sequence similarity; hypothetical protein 347215..348258 Mycoplasma genitalium G37 875726 NP_072953.1 CDS MG_286 NC_000908.2 348261 348851 D identified by sequence similarity; hypothetical protein 348261..348851 Mycoplasma genitalium G37 875276 NP_072954.1 CDS MG_287 NC_000908.2 348883 349137 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 348883..349137 Mycoplasma genitalium G37 875396 NP_072955.1 CDS MG_289 NC_000908.2 354024 355130 D identified by sequence similarity; phosphonate ABC transporter substrate-binding protein 354024..355130 Mycoplasma genitalium G37 875389 NP_072956.1 CDS MG_290 NC_000908.2 355120 355857 D identified by sequence similarity; phosphonate ABC transporter ATP-binding protein 355120..355857 Mycoplasma genitalium G37 875241 NP_072957.1 CDS MG_291 NC_000908.2 355847 357478 D identified by sequence similarity; phosphonate ABC transporter permease 355847..357478 Mycoplasma genitalium G37 875242 NP_072958.1 CDS MG_505 NC_000908.2 357475 357891 R identified by sequence similarity; hypothetical protein complement(357475..357891) Mycoplasma genitalium G37 875398 NP_072959.1 CDS alaS NC_000908.2 357891 360593 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(357891..360593) Mycoplasma genitalium G37 875339 NP_072960.1 CDS MG_293 NC_000908.2 360651 361385 R identified by sequence similarity; glycerophosphoryl diester phosphodiesterase family protein complement(360651..361385) Mycoplasma genitalium G37 875409 NP_072961.1 CDS MG_294 NC_000908.2 361378 362802 R identified by sequence similarity; major facilitator superfamily protein complement(361378..362802) Mycoplasma genitalium G37 875713 NP_072962.1 CDS mnmA NC_000908.2 362920 364023 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(362920..364023) Mycoplasma genitalium G37 875686 NP_072963.1 CDS MG_296 NC_000908.2 364026 364415 R identified by sequence similarity; hypothetical protein complement(364026..364415) Mycoplasma genitalium G37 875258 NP_072964.1 CDS ftsY NC_000908.2 364535 365575 R identified by sequence similarity; signal recognition particle-docking protein FtsY complement(364535..365575) Mycoplasma genitalium G37 875259 NP_072965.1 CDS MG_298 NC_000908.2 365582 368530 R identified by sequence similarity; chromosome segregation protein SMC complement(365582..368530) Mycoplasma genitalium G37 875295 NP_072966.1 CDS eutD NC_000908.2 368733 369695 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(368733..369695) Mycoplasma genitalium G37 875564 NP_072967.2 CDS pgk NC_000908.2 369713 370948 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(369713..370948) Mycoplasma genitalium G37 875582 NP_072968.1 CDS gap NC_000908.2 370950 371963 R catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase complement(370950..371963) Mycoplasma genitalium G37 875428 NP_072969.1 CDS MG_302 NC_000908.2 371994 372947 R identified by sequence similarity; metal ABC transporter permease complement(371994..372947) Mycoplasma genitalium G37 875429 NP_072970.1 CDS MG_303 NC_000908.2 372926 373999 R identified by sequence similarity; metal ABC transporter ATP-binding protein complement(372926..373999) Mycoplasma genitalium G37 875250 NP_072971.2 CDS MG_304 NC_000908.2 373981 374793 R identified by sequence similarity; metal ABC transporter ATP-binding protein complement(373981..374793) Mycoplasma genitalium G37 875412 NP_072972.1 CDS dnaK NC_000908.2 374919 376706 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(374919..376706) Mycoplasma genitalium G37 875435 NP_072973.1 CDS MG_306 NC_000908.2 376794 377975 R identified by sequence similarity; hypothetical protein complement(376794..377975) Mycoplasma genitalium G37 875436 NP_072974.1 CDS MG_307 NC_000908.2 377975 381508 R identified by sequence similarity; lipoprotein complement(377975..381508) Mycoplasma genitalium G37 875391 NP_072975.1 CDS MG_308 NC_000908.2 381493 382725 R identified by sequence similarity; DEAD-box ATP dependent DNA helicase complement(381493..382725) Mycoplasma genitalium G37 875443 NP_072976.2 CDS MG_309 NC_000908.2 382732 386409 R identified by sequence similarity; lipoprotein complement(382732..386409) Mycoplasma genitalium G37 875555 NP_072977.1 CDS MG_310 NC_000908.2 386463 387269 D identified by sequence similarity; alpha/beta fold family hydrolase 386463..387269 Mycoplasma genitalium G37 875556 NP_072978.1 CDS rpsD NC_000908.2 387276 387893 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(387276..387893) Mycoplasma genitalium G37 875565 NP_072979.1 CDS hmw1 NC_000908.2 387916 391335 R identified by sequence similarity; HMW1 cytadherence accessory protein complement(387916..391335) Mycoplasma genitalium G37 875568 NP_072980.1 CDS MG_313 NC_000908.2 391395 392258 R identified by sequence similarity; hypothetical protein complement(391395..392258) Mycoplasma genitalium G37 875569 NP_072981.1 CDS MG_314 NC_000908.2 392303 393634 R identified by sequence similarity; hypothetical protein complement(392303..393634) Mycoplasma genitalium G37 875244 NP_072982.1 CDS MG_315 NC_000908.2 393658 394551 R identified by sequence similarity; DNA polymerase III subunit delta complement(393658..394551) Mycoplasma genitalium G37 875245 NP_072983.1 CDS MG_316 NC_000908.2 394475 395584 R identified by sequence similarity; ComEC/Rec2-related protein complement(394475..395584) Mycoplasma genitalium G37 875578 NP_072984.1 CDS hmw3 NC_000908.2 395625 397424 R identified by sequence similarity; HMW3 cytadherence accessory protein complement(395625..397424) Mycoplasma genitalium G37 875571 NP_072985.1 CDS MG_318 NC_000908.2 397439 398281 R identified by sequence similarity; P32 adhesin complement(397439..398281) Mycoplasma genitalium G37 875572 NP_072986.1 CDS MG_319 NC_000908.2 398298 398834 R identified by sequence similarity; hypothetical protein complement(398298..398834) Mycoplasma genitalium G37 875559 NP_072987.1 CDS MG_320 NC_000908.2 398938 399798 R identified by sequence similarity; hypothetical protein complement(398938..399798) Mycoplasma genitalium G37 875560 NP_072989.1 CDS MG_321 NC_000908.2 400119 402923 R identified by sequence similarity; lipoprotein complement(400119..402923) Mycoplasma genitalium G37 875580 NP_072990.1 CDS MG_322 NC_000908.2 403723 405399 R identified by sequence similarity; TrkH family potassium uptake protein complement(403723..405399) Mycoplasma genitalium G37 875495 NP_072991.1 CDS MG_323 NC_000908.2 405456 406139 D identified by sequence similarity; TrkA family potassium uptake protein 405456..406139 Mycoplasma genitalium G37 875521 NP_072992.1 CDS MG_515 NC_000908.2 406975 407784 R identified by sequence similarity; hypothetical protein complement(406975..407784) Mycoplasma genitalium G37 875522 NP_072993.1 CDS pepP NC_000908.2 407729 408793 R identified by sequence similarity; M24 family metallopeptidase complement(407729..408793) Mycoplasma genitalium G37 875523 NP_072994.1 CDS rpmG NC_000908.2 408793 408954 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 complement(408793..408954) Mycoplasma genitalium G37 875268 NP_072995.1 CDS MG_326 NC_000908.2 408971 409858 R identified by sequence similarity; degV family protein complement(408971..409858) Mycoplasma genitalium G37 875269 NP_072996.1 CDS MG_327 NC_000908.2 409871 410677 R identified by sequence similarity; alpha/beta fold family hydrolase complement(409871..410677) Mycoplasma genitalium G37 875487 NP_072997.1 CDS MG_328 NC_000908.2 410664 412934 R identified by sequence similarity; hypothetical protein complement(410664..412934) Mycoplasma genitalium G37 875488 NP_072998.1 CDS engA NC_000908.2 412973 414319 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(412973..414319) Mycoplasma genitalium G37 875272 NP_072999.1 CDS cmk NC_000908.2 414323 414976 R identified by sequence similarity; cytidylate kinase complement(414323..414976) Mycoplasma genitalium G37 875273 NP_073000.1 CDS MG_331 NC_000908.2 414985 415623 R identified by sequence similarity; hypothetical protein complement(414985..415623) Mycoplasma genitalium G37 875439 NP_073001.1 CDS MG_332 NC_000908.2 415611 416330 R identified by sequence similarity; hypothetical protein complement(415611..416330) Mycoplasma genitalium G37 875440 NP_073002.1 CDS valS NC_000908.2 416967 419480 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(416967..419480) Mycoplasma genitalium G37 875510 NP_073003.1 CDS engB NC_000908.2 419470 420045 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(419470..420045) Mycoplasma genitalium G37 875511 NP_073004.1 CDS MG_516 NC_000908.2 420053 420274 R hypothetical protein; identified by GeneMark; hypothetical protein complement(420053..420274) Mycoplasma genitalium G37 875262 NP_073005.1 CDS MG_517 NC_000908.2 420333 421358 D identified by sequence similarity; glycosyl transferase, group 2 family protein 420333..421358 Mycoplasma genitalium G37 875263 NP_073006.1 CDS nifS NC_000908.2 421467 422693 D identified by sequence similarity; aminotransferase, class V 421467..422693 Mycoplasma genitalium G37 875461 NP_073007.1 CDS MG_337 NC_000908.2 422697 423113 D identified by sequence similarity; hypothetical protein 422697..423113 Mycoplasma genitalium G37 875462 NP_073008.2 CDS MG_338 NC_000908.2 423100 426912 R identified by sequence similarity; lipoprotein complement(423100..426912) Mycoplasma genitalium G37 875419 NP_073009.1 CDS recA NC_000908.2 427090 428112 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(427090..428112) Mycoplasma genitalium G37 875420 NP_073010.2 CDS rpoC NC_000908.2 430580 434458 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(430580..434458) Mycoplasma genitalium G37 875481 NP_073011.1 CDS rpoB NC_000908.2 434468 438640 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(434468..438640) Mycoplasma genitalium G37 875482 NP_073012.1 CDS MG_342 NC_000908.2 438730 439236 R identified by sequence similarity; NADPH-dependent FMN reductase domain-containing protein complement(438730..439236) Mycoplasma genitalium G37 875477 NP_073013.1 CDS MG_343 NC_000908.2 439315 440355 R identified by sequence similarity; hypothetical protein complement(439315..440355) Mycoplasma genitalium G37 875478 NP_073014.1 CDS MG_344 NC_000908.2 440359 441180 R identified by sequence similarity; alpha/beta fold family hydrolase complement(440359..441180) Mycoplasma genitalium G37 875479 NP_073015.2 CDS ileS NC_000908.2 441191 443878 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(441191..443878) Mycoplasma genitalium G37 875496 NP_073016.1 CDS MG_346 NC_000908.2 443922 444422 D identified by sequence similarity; RNA methyltransferase 443922..444422 Mycoplasma genitalium G37 875497 NP_073017.1 CDS MG_347 NC_000908.2 444413 445045 D identified by sequence similarity; tRNA (guanine-N(7)-)-methyltransferase 444413..445045 Mycoplasma genitalium G37 875414 NP_073018.1 CDS MG_348 NC_000908.2 445197 446165 R identified by sequence similarity; lipoprotein complement(445197..446165) Mycoplasma genitalium G37 875457 NP_073019.1 CDS MG_349 NC_000908.2 446576 447790 D identified by sequence similarity; hypothetical protein 446576..447790 Mycoplasma genitalium G37 875459 NP_073020.1 CDS MG_350 NC_000908.2 447790 448725 D identified by sequence similarity; hypothetical protein 447790..448725 Mycoplasma genitalium G37 875449 NP_073021.1 CDS MG_521 NC_000908.2 448943 449617 R identified by sequence similarity; hypothetical protein complement(448943..449617) Mycoplasma genitalium G37 875278 NP_073022.1 CDS ppa NC_000908.2 449665 450219 D catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 449665..450219 Mycoplasma genitalium G37 875279 NP_073023.1 CDS MG_352 NC_000908.2 450222 450722 D identified by sequence similarity; recombination protein U 450222..450722 Mycoplasma genitalium G37 875290 NP_073024.1 CDS MG_353 NC_000908.2 450719 451048 R identified by sequence similarity; DNA-binding protein HU complement(450719..451048) Mycoplasma genitalium G37 875291 NP_073025.1 CDS MG_354 NC_000908.2 451197 451610 D identified by sequence similarity; hypothetical protein 451197..451610 Mycoplasma genitalium G37 875344 NP_073026.1 CDS clpB NC_000908.2 451613 453757 R identified by sequence similarity; ATP-dependent Clp protease ATPase subunit complement(451613..453757) Mycoplasma genitalium G37 875345 NP_073027.1 CDS MG_356 NC_000908.2 453911 454753 R identified by sequence similarity; choline/ethanolamine kinase complement(453911..454753) Mycoplasma genitalium G37 875346 NP_073028.1 CDS ackA NC_000908.2 454766 455947 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(454766..455947) Mycoplasma genitalium G37 875501 NP_073029.2 CDS ruvA NC_000908.2 456755 457372 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 456755..457372 Mycoplasma genitalium G37 875502 NP_073030.1 CDS ruvB NC_000908.2 457347 458270 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 457347..458270 Mycoplasma genitalium G37 875515 NP_073031.1 CDS MG_360 NC_000908.2 458260 459495 R identified by sequence similarity; ImpB/MucB/SamB family protein complement(458260..459495) Mycoplasma genitalium G37 875516 NP_073032.1 CDS rplJ NC_000908.2 459615 460103 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 459615..460103 Mycoplasma genitalium G37 875505 NP_073033.1 CDS rplL NC_000908.2 460126 460494 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 460126..460494 Mycoplasma genitalium G37 875506 NP_073034.1 CDS rpmF NC_000908.2 460497 460670 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 460497..460670 Mycoplasma genitalium G37 875222 NP_073035.1 CDS rpsT NC_000908.2 460685 460951 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(460685..460951) Mycoplasma genitalium G37 875223 NP_073036.1 CDS MG_364 NC_000908.2 461015 461689 D identified by sequence similarity; hypothetical protein 461015..461689 Mycoplasma genitalium G37 875423 NP_073037.1 CDS fmt NC_000908.2 461682 462617 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 461682..462617 Mycoplasma genitalium G37 875424 NP_073038.1 CDS MG_366 NC_000908.2 462619 464622 D identified by sequence similarity; hypothetical protein 462619..464622 Mycoplasma genitalium G37 875425 NP_073039.1 CDS rnc NC_000908.2 464646 465434 R identified by sequence similarity; ribonuclease III complement(464646..465434) Mycoplasma genitalium G37 875426 NP_073040.1 CDS plsX NC_000908.2 465424 466410 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX complement(465424..466410) Mycoplasma genitalium G37 875490 NP_073041.1 CDS MG_369 NC_000908.2 466410 468083 R identified by sequence similarity; DAK2 domain-containing protein complement(466410..468083) Mycoplasma genitalium G37 875491 NP_073042.1 CDS MG_370 NC_000908.2 468152 469123 R identified by sequence similarity; RluA family pseudouridine synthase complement(468152..469123) Mycoplasma genitalium G37 875682 NP_073043.1 CDS MG_371 NC_000908.2 469110 470084 R identified by sequence similarity; DHH family protein complement(469110..470084) Mycoplasma genitalium G37 875683 NP_073044.1 CDS guaA NC_000908.2 470077 471234 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(470077..471234) Mycoplasma genitalium G37 875684 NP_073045.1 CDS MG_373 NC_000908.2 471221 472066 R identified by sequence similarity; hypothetical protein complement(471221..472066) Mycoplasma genitalium G37 875680 NP_073046.1 CDS MG_374 NC_000908.2 472067 472891 R identified by sequence similarity; hypothetical protein complement(472067..472891) Mycoplasma genitalium G37 875681 NP_073047.1 CDS thrS NC_000908.2 472884 474578 R identified by sequence similarity; threonyl-tRNA synthetase complement(472884..474578) Mycoplasma genitalium G37 875678 NP_073048.1 CDS MG_376 NC_000908.2 474578 474892 R identified by sequence similarity; hypothetical protein complement(474578..474892) Mycoplasma genitalium G37 875679 NP_073049.1 CDS MG_377 NC_000908.2 474898 475479 R identified by sequence similarity; hypothetical protein complement(474898..475479) Mycoplasma genitalium G37 875676 NP_073050.1 CDS argS NC_000908.2 475526 477139 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(475526..477139) Mycoplasma genitalium G37 875677 NP_073051.1 CDS gidA NC_000908.2 477168 479006 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 477168..479006 Mycoplasma genitalium G37 875674 NP_073052.1 CDS gidB NC_000908.2 478999 479577 D identified by sequence similarity; methyltransferase GidB 478999..479577 Mycoplasma genitalium G37 875675 NP_073053.1 CDS MG_381 NC_000908.2 479570 480226 D identified by sequence similarity; hypothetical protein 479570..480226 Mycoplasma genitalium G37 875671 NP_073054.1 CDS udk NC_000908.2 480691 481332 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 480691..481332 Mycoplasma genitalium G37 875673 NP_073055.1 CDS MG_383 NC_000908.2 481329 482075 R identified by sequence similarity; NH(3)-dependent NAD+ synthetase complement(481329..482075) Mycoplasma genitalium G37 875669 NP_073056.1 CDS obgE NC_000908.2 482068 483369 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(482068..483369) Mycoplasma genitalium G37 875670 NP_073057.1 CDS MG_524 NC_000908.2 483369 483818 R identified by sequence similarity; hypothetical protein complement(483369..483818) Mycoplasma genitalium G37 875667 NP_073058.1 CDS MG_385 NC_000908.2 483989 484699 R identified by sequence similarity; glycerophosphoryl diester phosphodiesterase family protein complement(483989..484699) Mycoplasma genitalium G37 875668 NP_073059.1 CDS MG_386 NC_000908.2 484702 489552 R identified by sequence similarity; hypothetical protein complement(484702..489552) Mycoplasma genitalium G37 875665 NP_073060.1 CDS era NC_000908.2 489839 490711 R identified by sequence similarity; GTP-binding protein Era complement(489839..490711) Mycoplasma genitalium G37 875666 NP_073061.2 CDS MG_388 NC_000908.2 490699 491163 R identified by sequence similarity; hypothetical protein complement(490699..491163) Mycoplasma genitalium G37 875663 NP_073062.1 CDS MG_389 NC_000908.2 491147 491530 R identified by sequence similarity; hypothetical protein complement(491147..491530) Mycoplasma genitalium G37 875664 NP_073063.1 CDS MG_390 NC_000908.2 491534 493516 R identified by sequence similarity; ABC transporter ATP-binding protein/permease complement(491534..493516) Mycoplasma genitalium G37 875660 NP_073064.1 CDS MG_391 NC_000908.2 493624 494967 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(493624..494967) Mycoplasma genitalium G37 875661 NP_073065.2 CDS groEL NC_000908.2 494984 496615 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(494984..496615) Mycoplasma genitalium G37 875662 NP_073066.1 CDS groES NC_000908.2 496628 496960 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP-binding and hydrolysis in the trans ring; co-chaperonin GroES complement(496628..496960) Mycoplasma genitalium G37 875658 NP_073067.1 CDS glyA NC_000908.2 497086 498306 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(497086..498306) Mycoplasma genitalium G37 875659 NP_073068.1 CDS MG_395 NC_000908.2 498316 499890 R identified by sequence similarity; lipoprotein complement(498316..499890) Mycoplasma genitalium G37 875656 NP_073069.1 CDS MG_396 NC_000908.2 500261 500719 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B complement(500261..500719) Mycoplasma genitalium G37 875657 NP_073070.1 CDS MG_397 NC_000908.2 500720 502420 R identified by sequence similarity; hypothetical protein complement(500720..502420) Mycoplasma genitalium G37 875654 NP_073071.1 CDS atpC NC_000908.2 502422 502823 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(502422..502823) Mycoplasma genitalium G37 875655 NP_073072.1 CDS atpD NC_000908.2 502828 504258 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(502828..504258) Mycoplasma genitalium G37 875652 NP_073073.1 CDS atpG NC_000908.2 504260 505099 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(504260..505099) Mycoplasma genitalium G37 875653 NP_073074.1 CDS atpA NC_000908.2 505099 506655 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(505099..506655) Mycoplasma genitalium G37 875650 NP_073075.1 CDS atpH NC_000908.2 506671 507201 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(506671..507201) Mycoplasma genitalium G37 875651 NP_073076.1 CDS atpF NC_000908.2 507194 507820 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(507194..507820) Mycoplasma genitalium G37 875648 NP_073077.1 CDS atpE NC_000908.2 507823 508131 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(507823..508131) Mycoplasma genitalium G37 875649 NP_073078.1 CDS atpB NC_000908.2 508134 509012 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(508134..509012) Mycoplasma genitalium G37 875646 NP_073079.2 CDS MG_406 NC_000908.2 508978 509454 R identified by sequence similarity; hypothetical protein complement(508978..509454) Mycoplasma genitalium G37 875647 NP_073080.1 CDS eno NC_000908.2 509460 510836 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(509460..510836) Mycoplasma genitalium G37 875644 NP_073081.1 CDS pmsR NC_000908.2 510903 511376 D this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 510903..511376 Mycoplasma genitalium G37 875645 NP_073082.1 CDS MG_409 NC_000908.2 511373 512050 R identified by sequence similarity; phosphate transport system regulatory protein PhoU complement(511373..512050) Mycoplasma genitalium G37 875641 NP_073083.1 CDS pstB NC_000908.2 512053 513042 R identified by sequence similarity; phosphate ABC transporter ATP-binding protein complement(512053..513042) Mycoplasma genitalium G37 875642 NP_073084.1 CDS pstA NC_000908.2 513027 514991 R identified by sequence similarity; phosphate ABC transporter permease complement(513027..514991) Mycoplasma genitalium G37 875643 NP_073085.1 CDS MG_412 NC_000908.2 514991 516124 R identified by sequence similarity; phosphate ABC transporter substrate-binding protein complement(514991..516124) Mycoplasma genitalium G37 875639 NP_073086.1 CDS MG_414 NC_000908.2 516245 519355 R identified by sequence similarity; hypothetical protein complement(516245..519355) Mycoplasma genitalium G37 875640 NP_073087.2 CDS MG_525 NC_000908.2 519420 521414 R identified by sequence similarity; hypothetical protein complement(519420..521414) Mycoplasma genitalium G37 875637 NP_073088.1 CDS rpsI NC_000908.2 521470 521868 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(521470..521868) Mycoplasma genitalium G37 875638 NP_073089.1 CDS rplM NC_000908.2 521874 522314 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(521874..522314) Mycoplasma genitalium G37 875635 NP_073090.2 CDS MG_419 NC_000908.2 522352 524145 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau complement(522352..524145) Mycoplasma genitalium G37 875636 NP_073092.1 CDS uvrA NC_000908.2 524151 527015 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(524151..527015) Mycoplasma genitalium G37 875634 NP_073093.1 CDS MG_422 NC_000908.2 526987 529494 R identified by sequence similarity; hypothetical protein complement(526987..529494) Mycoplasma genitalium G37 875630 NP_073094.1 CDS MG_423 NC_000908.2 529532 531217 R identified by sequence similarity; hypothetical protein complement(529532..531217) Mycoplasma genitalium G37 875631 NP_073095.1 CDS rpsO NC_000908.2 531220 531480 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(531220..531480) Mycoplasma genitalium G37 875632 NP_073096.1 CDS deaD NC_000908.2 531669 533018 D identified by sequence similarity; DEAD-box ATP dependent DNA helicase 531669..533018 Mycoplasma genitalium G37 875628 NP_073097.1 CDS rpmB NC_000908.2 533041 533235 D required for 70S ribosome assembly; 50S ribosomal protein L28 533041..533235 Mycoplasma genitalium G37 875629 NP_073098.1 CDS MG_427 NC_000908.2 533271 533696 D identified by sequence similarity; OsmC-like protein 533271..533696 Mycoplasma genitalium G37 875626 NP_073099.1 CDS MG_428 NC_000908.2 533807 534322 D identified by sequence similarity; LuxR regulatory protein 533807..534322 Mycoplasma genitalium G37 875627 NP_073100.1 CDS ptsI NC_000908.2 534319 536037 R identified by sequence similarity; phosphoenolpyruvate-protein phosphotransferase complement(534319..536037) Mycoplasma genitalium G37 875624 NP_073101.2 CDS pgm NC_000908.2 536041 537564 R catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase complement(536041..537564) Mycoplasma genitalium G37 875625 NP_073102.1 CDS tpiA NC_000908.2 537557 538291 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(537557..538291) Mycoplasma genitalium G37 875622 NP_073103.1 CDS MG_432 NC_000908.2 538351 539547 R identified by sequence similarity; hypothetical protein complement(538351..539547) Mycoplasma genitalium G37 875623 NP_073104.1 CDS tsf NC_000908.2 539633 540529 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 539633..540529 Mycoplasma genitalium G37 875620 NP_073105.1 CDS pyrH NC_000908.2 540510 541241 D identified by sequence similarity; uridylate kinase 540510..541241 Mycoplasma genitalium G37 875621 NP_073106.1 CDS frr NC_000908.2 541241 541792 D identified by sequence similarity; ribosome recycling factor 541241..541792 Mycoplasma genitalium G37 875618 NP_073107.2 CDS MG_437 NC_000908.2 541793 542986 D hypothetical protein; identified by GeneMark; phosphatidate cytidylyltransferase 541793..542986 Mycoplasma genitalium G37 875619 NP_073108.1 CDS MG_438 NC_000908.2 543006 544157 D identified by sequence similarity; type I restriction modification DNA specificity domain-containing protein 543006..544157 Mycoplasma genitalium G37 875615 NP_073109.1 CDS MG_439 NC_000908.2 544562 545380 R identified by sequence similarity; lipoprotein complement(544562..545380) Mycoplasma genitalium G37 875616 NP_073110.1 CDS MG_440 NC_000908.2 545380 546156 R identified by sequence similarity; lipoprotein complement(545380..546156) Mycoplasma genitalium G37 875617 NP_073111.1 CDS MG_441 NC_000908.2 546299 546709 R identified by sequence similarity; hypothetical protein complement(546299..546709) Mycoplasma genitalium G37 875613 NP_073112.1 CDS rbgA NC_000908.2 546880 547692 R essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase complement(546880..547692) Mycoplasma genitalium G37 875614 NP_073113.1 CDS MG_443 NC_000908.2 547664 548851 R identified by sequence similarity; hypothetical protein complement(547664..548851) Mycoplasma genitalium G37 875611 NP_073114.1 CDS rplS NC_000908.2 548867 549226 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(548867..549226) Mycoplasma genitalium G37 875612 NP_073115.1 CDS trmD NC_000908.2 549210 549905 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(549210..549905) Mycoplasma genitalium G37 875609 NP_073116.2 CDS rpsP NC_000908.2 549905 550192 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(549905..550192) Mycoplasma genitalium G37 875610 NP_073117.1 CDS MG_447 NC_000908.2 550803 552446 R identified by sequence similarity; hypothetical protein complement(550803..552446) Mycoplasma genitalium G37 875606 NP_073118.1 CDS MG_448 NC_000908.2 552447 552899 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(552447..552899) Mycoplasma genitalium G37 875607 NP_073120.2 CDS MG_450 NC_000908.2 553558 554430 R identified by sequence similarity; degV family protein complement(553558..554430) Mycoplasma genitalium G37 875604 NP_073121.1 CDS tuf NC_000908.2 554430 555614 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(554430..555614) Mycoplasma genitalium G37 875605 NP_073122.1 CDS MG_452 NC_000908.2 555667 556452 D identified by sequence similarity; hypothetical protein 555667..556452 Mycoplasma genitalium G37 875602 NP_073123.1 CDS gtaB NC_000908.2 556437 557315 D identified by sequence similarity; UTP-glucose-1-phosphate uridylyltransferase 556437..557315 Mycoplasma genitalium G37 875603 NP_073124.1 CDS MG_454 NC_000908.2 557305 557772 R identified by sequence similarity; OsmC-like protein complement(557305..557772) Mycoplasma genitalium G37 875600 NP_073125.2 CDS tyrS NC_000908.2 557759 558949 D identified by sequence similarity; tyrosyl-tRNA synthetase 557759..558949 Mycoplasma genitalium G37 875601 NP_073126.1 CDS MG_456 NC_000908.2 558939 559943 R identified by sequence similarity; hypothetical protein complement(558939..559943) Mycoplasma genitalium G37 875597 NP_073127.1 CDS ftsH NC_000908.2 560496 562604 R identified by sequence similarity; ATP-dependent metalloprotease FtsH complement(560496..562604) Mycoplasma genitalium G37 875598 NP_073128.1 CDS hpt NC_000908.2 562782 563309 R identified by sequence similarity; hypoxanthine phosphoribosyltransferase complement(562782..563309) Mycoplasma genitalium G37 875599 NP_073129.1 CDS MG_459 NC_000908.2 563311 563820 R identified by sequence similarity; hypothetical protein complement(563311..563820) Mycoplasma genitalium G37 875595 NP_073130.1 CDS ldh NC_000908.2 563993 564931 D identified by sequence similarity; lactate dehydrogenase 563993..564931 Mycoplasma genitalium G37 875596 NP_073131.2 CDS MG_461 NC_000908.2 564928 566205 R identified by sequence similarity; HD domain-containing protein complement(564928..566205) Mycoplasma genitalium G37 875593 NP_073132.1 CDS gltX NC_000908.2 566186 567640 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(566186..567640) Mycoplasma genitalium G37 875594 NP_073133.1 CDS ksgA NC_000908.2 567627 568406 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(567627..568406) Mycoplasma genitalium G37 875591 NP_073134.1 CDS MG_464 NC_000908.2 568399 569556 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC complement(568399..569556) Mycoplasma genitalium G37 875592 NP_073135.1 CDS rnpA NC_000908.2 569528 569914 R identified by sequence similarity; ribonuclease P protein component complement(569528..569914) Mycoplasma genitalium G37 875589 NP_073136.1 CDS rpmH NC_000908.2 569883 570029 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(569883..570029) Mycoplasma genitalium G37 875590 NP_073137.1 CDS MG_467 NC_000908.2 570055 570990 R identified by sequence similarity; ABC transporter ATP-binding protein complement(570055..570990) Mycoplasma genitalium G37 875586 NP_073138.1 CDS MG_468 NC_000908.2 570994 576345 R identified by sequence similarity; ABC transporter permease complement(570994..576345) Mycoplasma genitalium G37 875587 NP_073139.1 CDS MG_526 NC_000908.2 576351 577205 R identified by sequence similarity; ABC transporter ATP-binding protein complement(576351..577205) Mycoplasma genitalium G37 875588 NP_073140.1 CDS dnaA NC_000908.2 577268 578581 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(577268..578581) Mycoplasma genitalium G37 875584 NP_073141.1 CDS soj NC_000908.2 579224 580033 R identified by sequence similarity; CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein complement(579224..580033) Mycoplasma genitalium G37 875585 MG_471 tRNA MG_471 NC_000908.2 15294 15369 R tRNA-Ala complement(15294..15369) Mycoplasma genitalium G37 875702 MG_472 tRNA MG_472 NC_000908.2 15375 15451 R tRNA-Ile complement(15375..15451) Mycoplasma genitalium G37 875218 MG_475 tRNA MG_475 NC_000908.2 70393 70481 R tRNA-Ser complement(70393..70481) Mycoplasma genitalium G37 875704 MG_479 tRNA MG_479 NC_000908.2 240213 240286 R tRNA-Thr complement(240213..240286) Mycoplasma genitalium G37 875252 MG_483 tRNA MG_483 NC_000908.2 257158 257234 D tRNA-Cys 257158..257234 Mycoplasma genitalium G37 875336 MG_484 tRNA MG_484 NC_000908.2 257269 257345 D tRNA-Pro 257269..257345 Mycoplasma genitalium G37 875294 MG_485 tRNA MG_485 NC_000908.2 257349 257425 D tRNA-Met 257349..257425 Mycoplasma genitalium G37 875323 MG_486 tRNA MG_486 NC_000908.2 257445 257521 D tRNA-Met 257445..257521 Mycoplasma genitalium G37 875366 MG_487 tRNA MG_487 NC_000908.2 257559 257650 D tRNA-Ser 257559..257650 Mycoplasma genitalium G37 875365 MG_488 tRNA MG_488 NC_000908.2 257664 257740 D tRNA-Met 257664..257740 Mycoplasma genitalium G37 875364 MG_489 tRNA MG_489 NC_000908.2 257742 257815 D tRNA-Asp 257742..257815 Mycoplasma genitalium G37 875363 MG_490 tRNA MG_490 NC_000908.2 257818 257893 D tRNA-Phe 257818..257893 Mycoplasma genitalium G37 875362 MG_492 tRNA MG_492 NC_000908.2 266423 266499 D tRNA-Arg 266423..266499 Mycoplasma genitalium G37 875356 MG_493 tRNA MG_493 NC_000908.2 304892 304965 R tRNA-Gly complement(304892..304965) Mycoplasma genitalium G37 875329 MG_495 tRNA MG_495 NC_000908.2 306617 306691 D tRNA-Arg 306617..306691 Mycoplasma genitalium G37 875355 MG_496 tRNA MG_496 NC_000908.2 306740 306813 D tRNA-Trp 306740..306813 Mycoplasma genitalium G37 875354 MG_497 tRNA MG_497 NC_000908.2 315301 315377 R tRNA-Arg complement(315301..315377) Mycoplasma genitalium G37 875382 MG_499 tRNA MG_499 NC_000908.2 343884 343957 R tRNA-Gly complement(343884..343957) Mycoplasma genitalium G37 875705 MG_500 tRNA MG_500 NC_000908.2 343965 344050 R tRNA-Leu complement(343965..344050) Mycoplasma genitalium G37 875292 MG_501 tRNA MG_501 NC_000908.2 344051 344125 R tRNA-Lys complement(344051..344125) Mycoplasma genitalium G37 875710 MG_502 tRNA MG_502 NC_000908.2 344172 344246 R tRNA-Gln complement(344172..344246) Mycoplasma genitalium G37 875734 MG_503 tRNA MG_503 NC_000908.2 344251 344337 R tRNA-Tyr complement(344251..344337) Mycoplasma genitalium G37 875735 MG_504 tRNA MG_504 NC_000908.2 349128 349202 D tRNA-Sec 349128..349202 Mycoplasma genitalium G37 875376 MG_506 tRNA MG_506 NC_000908.2 399868 399958 D tRNA-Ser 399868..399958 Mycoplasma genitalium G37 875574 MG_507 tRNA MG_507 NC_000908.2 399960 400048 D tRNA-Ser 399960..400048 Mycoplasma genitalium G37 875579 MG_508 tRNA MG_508 NC_000908.2 403134 403218 R tRNA-Leu complement(403134..403218) Mycoplasma genitalium G37 875566 MG_509 tRNA MG_509 NC_000908.2 403224 403299 R tRNA-Lys complement(403224..403299) Mycoplasma genitalium G37 875567 MG_510 tRNA MG_510 NC_000908.2 403306 403381 R tRNA-Thr complement(403306..403381) Mycoplasma genitalium G37 875576 MG_511 tRNA MG_511 NC_000908.2 403383 403458 R tRNA-Val complement(403383..403458) Mycoplasma genitalium G37 875577 MG_512 tRNA MG_512 NC_000908.2 403467 403541 R tRNA-Thr complement(403467..403541) Mycoplasma genitalium G37 875561 MG_513 tRNA MG_513 NC_000908.2 403544 403620 R tRNA-Glu complement(403544..403620) Mycoplasma genitalium G37 875562 MG_514 tRNA MG_514 NC_000908.2 403627 403701 R tRNA-Asn complement(403627..403701) Mycoplasma genitalium G37 875494 MG_518 tRNA MG_518 NC_000908.2 445078 445153 D tRNA-His 445078..445153 Mycoplasma genitalium G37 875415 MG_519 tRNA MG_519 NC_000908.2 446178 446265 R tRNA-Leu complement(446178..446265) Mycoplasma genitalium G37 875458 MG_520 tRNA MG_520 NC_000908.2 448783 448864 D tRNA-Leu 448783..448864 Mycoplasma genitalium G37 875450 MG_523 tRNA MG_523 NC_000908.2 480240 480315 R tRNA-Arg complement(480240..480315) Mycoplasma genitalium G37 875672 MG_rrnA16S rRNA rrsA NC_000908.2 170007 171525 D 16S ribosomal RNA 170007..171525 Mycoplasma genitalium G37 875400 MG_rrnA23S rRNA rrlA NC_000908.2 171728 174645 D 23S ribosomal RNA 171728..174645 Mycoplasma genitalium G37 875271 MG_rrnA5S rRNA rrfA NC_000908.2 174685 174793 D 5S ribosomal RNA 174685..174793 Mycoplasma genitalium G37 875536