-- dump date   	20111121_013432
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_015698.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_015699.1	COG0592; expression validated by proteogenomic mapping: 18 unique peptides covering 44.2% of sequence
YP_015700.1	COG2501; expression validated by proteogenomic mapping: 1 unique peptides covering 19.1% of sequence
YP_015701.1	expression not validated
YP_015702.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_015703.1	expression validated by proteogenomic mapping: 10 unique peptides covering 22% of sequence
YP_015704.1	expression not validated
YP_015705.1	COG0226; expression validated by proteogenomic mapping: 15 unique peptides covering 42% of sequence
YP_015706.1	COG0581; COG0573; expression not validated
YP_015707.1	COG1117; expression validated by proteogenomic mapping: 12 unique peptides covering 52% of sequence
YP_015708.1	COG0704; expression validated by proteogenomic mapping: 11 unique peptides covering 43.7% of sequence
YP_015709.1	expression not validated
YP_015710.1	COG1172; expression validated by proteogenomic mapping: 6 unique peptides covering 8.6% of sequence
YP_015711.1	COG1129; expression validated by proteogenomic mapping: 32 unique peptides covering 50.5% of sequence
YP_015712.1	P46 antigen-like from M. hyorhinis; COG4213; expression validated by proteogenomic mapping: 76 unique peptides covering 67.8% of sequence
YP_015713.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_015714.1	COG2109; expression validated by proteogenomic mapping: 2 unique peptides covering 11.4% of sequence
YP_015715.1	expression validated by proteogenomic mapping: 4 unique peptides covering 35.3% of sequence
YP_015716.1	expression validated by proteogenomic mapping: 24 unique peptides covering 65% of sequence
YP_015717.1	expression validated by proteogenomic mapping: 43 unique peptides covering 71.4% of sequence
YP_015718.1	expression validated by proteogenomic mapping: 2 unique peptides covering 15.4% of sequence
YP_015719.1	expression validated by proteogenomic mapping: 31 unique peptides covering 41.4% of sequence
YP_015720.1	expression validated by proteogenomic mapping: 1 unique peptides covering 8.5% of sequence
YP_015721.1	expression validated by proteogenomic mapping: 33 unique peptides covering 42.6% of sequence
YP_015722.1	expression validated by proteogenomic mapping: 34 unique peptides covering 44.6% of sequence
YP_015723.1	expression validated by proteogenomic mapping: 30 unique peptides covering 40.1% of sequence
YP_015724.1	expression validated by proteogenomic mapping: 25 unique peptides covering 35.1% of sequence
YP_015725.1	expression validated by proteogenomic mapping: 4 unique peptides covering 50.6% of sequence
YP_015726.1	expression validated by proteogenomic mapping: 2 unique peptides covering 8.1% of sequence
YP_015727.1	expression not validated
YP_015728.1	expression validated by proteogenomic mapping: 3 unique peptides covering 22% of sequence
YP_015729.1	COG1518; expression validated by proteogenomic mapping: 2 unique peptides covering 6.7% of sequence
YP_015730.1	COG3513; expression validated by proteogenomic mapping: 57 unique peptides covering 40.2% of sequence
YP_015731.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_015732.1	COG0262; expression validated by proteogenomic mapping: 6 unique peptides covering 41.4% of sequence
YP_015733.1	antigen-like membrane protein; COG1744; expression validated by proteogenomic mapping: 39 unique peptides covering 54.6% of sequence
YP_015734.1	COG1129; expression validated by proteogenomic mapping: 35 unique peptides covering 55.9% of sequence
YP_015735.1	COG1079; expression validated by proteogenomic mapping: 20 unique peptides covering 20.7% of sequence
YP_015736.1	COG1079; expression validated by proteogenomic mapping: 3 unique peptides covering 6.6% of sequence
YP_015737.1	expression validated by proteogenomic mapping: 2 unique peptides covering 6.3% of sequence
YP_015738.1	COG0039; expression validated by proteogenomic mapping: 77 unique peptides covering 74.2% of sequence
YP_015739.1	COG0477; expression validated by proteogenomic mapping: 3 unique peptides covering 5.3% of sequence
YP_015740.1	COG0477; expression validated by proteogenomic mapping: 1 unique peptides covering 3% of sequence
YP_015741.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_015742.1	COG0561; expression validated by proteogenomic mapping: 41 unique peptides covering 75.2% of sequence
YP_015743.1	COG0561; expression validated by proteogenomic mapping: 17 unique peptides covering 47.2% of sequence
YP_015744.1	COG0561; expression validated by proteogenomic mapping: 7 unique peptides covering 33.1% of sequence
YP_015745.1	COG1130; expression validated by proteogenomic mapping: 32 unique peptides covering 56% of sequence
YP_015746.1	COG1176; expression not validated
YP_015747.1	COG1177; expression validated by proteogenomic mapping: 2 unique peptides covering 6.1% of sequence
YP_015748.1	expression validated by proteogenomic mapping: 25 unique peptides covering 50.1% of sequence
YP_015749.1	expression validated by proteogenomic mapping: 9 unique peptides covering 19.4% of sequence
YP_015750.1	COG2739; expression not validated
YP_015751.1	Catalyzes the phosphorylation of UMP to UDP
YP_015752.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_015753.1	COG0575; expression validated by proteogenomic mapping: 3 unique peptides covering 7.1% of sequence
YP_015754.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity
YP_015755.1	COG0095; expression validated by proteogenomic mapping: 22 unique peptides covering 63.3% of sequence
YP_015756.1	expression validated by proteogenomic mapping: 3 unique peptides covering 30.2% of sequence
YP_015757.1	expression validated by proteogenomic mapping: 3 unique peptides covering 9.8% of sequence
YP_015758.1	COG1080; expression validated by proteogenomic mapping: 83 unique peptides covering 67.8% of sequence
YP_015759.1	COG1263; COG1264; expression validated by proteogenomic mapping: 10 unique peptides covering 14.6% of sequence
YP_015760.1	COG0366; expression validated by proteogenomic mapping: 33 unique peptides covering 47.6% of sequence
YP_015761.1	possible sugar transport function; expression not validated
YP_015762.1	COG2190; expression validated by proteogenomic mapping: 16 unique peptides covering 65.8% of sequence
YP_015763.1	COG0596; expression validated by proteogenomic mapping: 6 unique peptides covering 33.3% of sequence
YP_015764.1	COG0618; expression validated by proteogenomic mapping: 8 unique peptides covering 31.9% of sequence
YP_015765.1	old yellow enzyme family; COG1902; expression validated by proteogenomic mapping: 37 unique peptides covering 77.1% of sequence
YP_015766.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_015767.1	expression validated by proteogenomic mapping: 16 unique peptides covering 32.6% of sequence
YP_015768.1	Required for the synthesis of the thiazole moiety
YP_015769.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_015770.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_015771.1	COG0718; expression validated by proteogenomic mapping: 2 unique peptides covering 22.1% of sequence
YP_015772.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_015773.1	COG0125; expression validated by proteogenomic mapping: 9 unique peptides covering 43.5% of sequence
YP_015774.1	expression validated by proteogenomic mapping: 3 unique peptides covering 6.4% of sequence
YP_015775.1	COG0822; expression validated by proteogenomic mapping: 2 unique peptides covering 12% of sequence
YP_015776.1	COG0520; expression validated by proteogenomic mapping: 17 unique peptides covering 42.4% of sequence
YP_015777.1	COG1189; expression validated by proteogenomic mapping: 1 unique peptides covering 5% of sequence
YP_015778.1	expression not validated
YP_015779.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_015780.1	COG1881; expression validated by proteogenomic mapping: 16 unique peptides covering 71.5% of sequence
YP_015781.1	expression validated by proteogenomic mapping: 10 unique peptides covering 43.6% of sequence
YP_015782.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_015783.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins
YP_015784.1	expression not validated
YP_015785.1	expression validated by proteogenomic mapping: 17 unique peptides covering 26.8% of sequence
YP_015786.1	COG0537; expression validated by proteogenomic mapping: 7 unique peptides covering 54.1% of sequence
YP_015787.1	similar to M. homonis P60; expression validated by proteogenomic mapping: 31 unique peptides covering 45.4% of sequence
YP_015788.1	expression validated by proteogenomic mapping: 71 unique peptides covering 58.4% of sequence
YP_015789.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_015790.1	COG0507; expression validated by proteogenomic mapping: 4 unique peptides covering 8.4% of sequence
YP_015791.1	expression not validated
YP_015792.1	COG2263; expression not validated
YP_015793.1	COG0507; expression validated by proteogenomic mapping: 3 unique peptides covering 22.5% of sequence
YP_015794.1	expression validated by proteogenomic mapping: 1 unique peptides covering 12% of sequence
YP_015795.1	expression validated by proteogenomic mapping: 10 unique peptides covering 15.7% of sequence
YP_015796.1	COG0737; expression validated by proteogenomic mapping: 30 unique peptides covering 41.4% of sequence
YP_015797.1	COG0686; expression validated by proteogenomic mapping: 49 unique peptides covering 79.3% of sequence
YP_015798.1	COG0187; expression validated by proteogenomic mapping: 48 unique peptides covering 56.1% of sequence
YP_015799.1	expression validated by proteogenomic mapping: 66 unique peptides covering 40.1% of sequence
YP_015800.1	expression validated by proteogenomic mapping: 252 unique peptides covering 55% of sequence
YP_015801.1	expression validated by proteogenomic mapping: 300 unique peptides covering 54.2% of sequence
YP_015802.1	expression validated by proteogenomic mapping: 15 unique peptides covering 37.6% of sequence
YP_015803.1	expression not validated
YP_015804.1	expression validated by proteogenomic mapping: 2 unique peptides covering 14.5% of sequence
YP_015805.1	expression not validated
YP_015806.1	expression validated by proteogenomic mapping: 3 unique peptides covering 20.9% of sequence
YP_015807.1	expression validated by proteogenomic mapping: 23 unique peptides covering 46.3% of sequence
YP_015808.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_015809.1	COG0576; expression validated by proteogenomic mapping: 33 unique peptides covering 69.6% of sequence
YP_015810.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_015811.1	COG0531; expression validated by proteogenomic mapping: 3 unique peptides covering 11.5% of sequence
YP_015812.1	COG0531; expression not validated
YP_015813.1	expression validated by proteogenomic mapping: 2 unique peptides covering 8.2% of sequence
YP_015814.1	COG1210; expression validated by proteogenomic mapping: 32 unique peptides covering 67.8% of sequence
YP_015815.1	COG0344; expression not validated
YP_015816.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
YP_015817.1	COG0566; expression validated by proteogenomic mapping: 3 unique peptides covering 13.4% of sequence
YP_015818.1	COG0219; expression validated by proteogenomic mapping: 1 unique peptides covering 5.8% of sequence
YP_015819.1	COG0561; expression validated by proteogenomic mapping: 18 unique peptides covering 59.6% of sequence
YP_015820.1	COG1039; expression validated by proteogenomic mapping: 3 unique peptides covering 20.7% of sequence
YP_015821.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_015822.1	expression validated by proteogenomic mapping: 3 unique peptides covering 40% of sequence
YP_015823.1	COG0191; expression validated by proteogenomic mapping: 45 unique peptides covering 85.2% of sequence
YP_015824.1	COG1525; expression not validated
YP_015825.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_015826.1	expression validated by proteogenomic mapping: 3 unique peptides covering 31.1% of sequence
YP_015827.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_015828.1	COG1214; expression validated by proteogenomic mapping: 5 unique peptides covering 26.1% of sequence
YP_015829.1	COG0802; expression validated by proteogenomic mapping: 2 unique peptides covering 17.6% of sequence
YP_015830.1	expression validated by proteogenomic mapping: 3 unique peptides covering 10.6% of sequence
YP_015831.1	expression validated by proteogenomic mapping: 12 unique peptides covering 32.6% of sequence
YP_015832.1	expression validated by proteogenomic mapping: 7 unique peptides covering 32.8% of sequence
YP_015833.1	expression validated by proteogenomic mapping: 36 unique peptides covering 33.1% of sequence
YP_015834.1	expression validated by proteogenomic mapping: 29 unique peptides covering 26.1% of sequence
YP_015835.1	COG0552; expression validated by proteogenomic mapping: 11 unique peptides covering 34.3% of sequence
YP_015836.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_015837.2	binds directly to 23S ribosomal RNA
YP_015838.1	COG0561; expression validated by proteogenomic mapping: 5 unique peptides covering 19% of sequence
YP_015839.1	COG3118; expression validated by proteogenomic mapping: 13 unique peptides covering 76% of sequence
YP_015840.1	COG3118; expression validated by proteogenomic mapping: 8 unique peptides covering 78.2% of sequence
YP_015841.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_015842.1	Modulates Rho-dependent transcription termination
YP_015843.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_015844.1	COG0566; expression validated by proteogenomic mapping: 5 unique peptides covering 30.9% of sequence
YP_015845.1	COG0215; expression validated by proteogenomic mapping: 11 unique peptides covering 28.3% of sequence
YP_015846.1	COG0779; expression not validated
YP_015847.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_015848.1	COG2740; expression validated by proteogenomic mapping: 1 unique peptides covering 17.1% of sequence
YP_015849.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_015850.1	COG0858; expression validated by proteogenomic mapping: 7 unique peptides covering 43.8% of sequence
YP_015851.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_015852.1	COG1576; expression validated by proteogenomic mapping: 2 unique peptides covering 19.6% of sequence
YP_015853.1	in some Mycoplasma, this protein is fused to aspartyl/glutamyl-tRNA amidotransferase subunit C domain
YP_015854.1	COG1124; expression validated by proteogenomic mapping: 20 unique peptides covering 28.1% of sequence
YP_015855.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_015856.1	expression validated by proteogenomic mapping: 6 unique peptides covering 64.9% of sequence
YP_015857.1	bifunctional enzyme; COG0190; expression validated by proteogenomic mapping: 13 unique peptides covering 53.9% of sequence
YP_015858.1	expression validated by proteogenomic mapping: 3 unique peptides covering 3.8% of sequence
YP_015859.1	expression validated by proteogenomic mapping: 50 unique peptides covering 72.4% of sequence
YP_015860.1	expression validated by proteogenomic mapping: 31 unique peptides covering 69% of sequence
YP_015861.1	expression validated by proteogenomic mapping: 18 unique peptides covering 67.7% of sequence
YP_015862.1	expression validated by proteogenomic mapping: 119 unique peptides covering 59.9% of sequence
YP_015863.1	one of multiple copies; COG0056; expression validated by proteogenomic mapping: 54 unique peptides covering 66.3% of sequence
YP_015864.2	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_015865.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
YP_015866.1	Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation
YP_015867.1	unknown function; putative protein prenyltransferase; COG1284; expression validated by proteogenomic mapping: 4 unique peptides covering 8.2% of sequence
YP_015868.1	COG0305; expression validated by proteogenomic mapping: 17 unique peptides covering 41.2% of sequence
YP_015869.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_015870.1	consists of a modified GGDEF domain and a DHH domain; COG3887; expression validated by proteogenomic mapping: 24 unique peptides covering 30.5% of sequence
YP_015871.1	COG0260; expression validated by proteogenomic mapping: 36 unique peptides covering 64.7% of sequence
YP_015872.1	COG1249; expression validated by proteogenomic mapping: 25 unique peptides covering 40% of sequence
YP_015873.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_015874.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_015875.1	COG1307; expression validated by proteogenomic mapping: 25 unique peptides covering 60.9% of sequence
YP_015876.1	COG1307; expression validated by proteogenomic mapping: 1 unique peptides covering 4.6% of sequence
YP_015877.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_015878.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_015879.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
YP_015880.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_015881.1	COG0492; expression validated by proteogenomic mapping: 51 unique peptides covering 78.5% of sequence
YP_015882.1	COG3611; expression validated by proteogenomic mapping: 1 unique peptides covering 2.8% of sequence
YP_015883.1	expression validated by proteogenomic mapping: 2 unique peptides covering 8.4% of sequence
YP_015884.1	COG0057; expression validated by proteogenomic mapping: 74 unique peptides covering 96.5% of sequence
YP_015885.1	expression not validated
YP_015886.1	COG2890; expression validated by proteogenomic mapping: 2 unique peptides covering 5.5% of sequence
YP_015887.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_015888.1	COG0217; expression validated by proteogenomic mapping: 12 unique peptides covering 34.4% of sequence
YP_015889.1	COG0171; expression validated by proteogenomic mapping: 6 unique peptides covering 20.4% of sequence
YP_015890.1	COG1087; expression validated by proteogenomic mapping: 26 unique peptides covering 48.5% of sequence
YP_015891.1	expression validated by proteogenomic mapping: 1 unique peptides covering 13.4% of sequence
YP_015892.1	COG0272; expression validated by proteogenomic mapping: 18 unique peptides covering 26.1% of sequence
YP_015893.1	COG1131; expression validated by proteogenomic mapping: 8 unique peptides covering 22.9% of sequence
YP_015894.1	similar to a M. penetrans protein; expression validated by proteogenomic mapping: 1 unique peptides covering 3.4% of sequence
YP_015895.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_015896.1	COG1164; expression validated by proteogenomic mapping: 36 unique peptides covering 49.8% of sequence
YP_015897.1	COG0596; expression validated by proteogenomic mapping: 4 unique peptides covering 18.4% of sequence
YP_015898.1	COG3527; expression validated by proteogenomic mapping: 25 unique peptides covering 61.9% of sequence
YP_015899.1	COG1109; expression validated by proteogenomic mapping: 14 unique peptides covering 19% of sequence
YP_015900.1	similar to sugar-related transcriptional regulator but lacks DNA-binding domain; COG1940; COG0837; expression validated by proteogenomic mapping: 28 unique peptides covering 58% of sequence
YP_015901.1	major facilitator superfamily; COG0477; expression validated by proteogenomic mapping: 1 unique peptides covering 3.3% of sequence
YP_015902.1	COG0584; expression validated by proteogenomic mapping: 2 unique peptides covering 11.4% of sequence
YP_015903.1	COG0531; expression validated by proteogenomic mapping: 4 unique peptides covering 10.2% of sequence
YP_015904.1	COG0355; expression validated by proteogenomic mapping: 7 unique peptides covering 46.8% of sequence
YP_015905.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_015906.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_015907.1	between atpG and atpA; expression validated by proteogenomic mapping: 1 unique peptides covering 25% of sequence
YP_015908.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_015909.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_015910.1	COG0711; expression validated by proteogenomic mapping: 22 unique peptides covering 53.8% of sequence
YP_015911.1	COG0636; expression not validated
YP_015912.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_015913.1	expression not validated
YP_015914.1	expression not validated
YP_015915.1	expression not validated
YP_015916.1	expression not validated
YP_015917.1	COG0236; expression validated by proteogenomic mapping: 7 unique peptides covering 69.6% of sequence
YP_015918.1	COG2116; expression validated by proteogenomic mapping: 3 unique peptides covering 11.3% of sequence
YP_015919.1	COG0531; expression not validated
YP_015920.1	COG2235; expression validated by proteogenomic mapping: 8 unique peptides covering 24.2% of sequence
YP_015921.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_015922.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_015923.1	COG0629; expression validated by proteogenomic mapping: 13 unique peptides covering 44% of sequence
YP_015924.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_015925.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_015926.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_015927.1	forms a direct contact with the tRNA during translation
YP_015928.1	COG4123; expression validated by proteogenomic mapping: 2 unique peptides covering 16.3% of sequence
YP_015929.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
YP_015930.1	expression not validated
YP_015931.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_015932.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_015933.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_015934.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_015935.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_015936.1	COG0185; expression validated by proteogenomic mapping: 9 unique peptides covering 75.8% of sequence
YP_015937.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_015938.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_015939.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_015940.1	one of the stabilizing components for the large ribosomal subunit
YP_015941.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_015942.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_015943.1	COG0198; expression validated by proteogenomic mapping: 16 unique peptides covering 60.8% of sequence
YP_015944.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_015945.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
YP_015946.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_015947.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_015948.1	binds 5S rRNA along with protein L5 and L25
YP_015949.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_015950.1	late assembly protein
YP_015951.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_015952.1	COG0563; expression validated by proteogenomic mapping: 23 unique peptides covering 71.4% of sequence
YP_015953.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_015954.1	COG0061; expression validated by proteogenomic mapping: 2 unique peptides covering 46.5% of sequence
YP_015955.1	COG0257; expression not validated
YP_015956.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_015957.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_015958.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_015959.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_015960.1	COG1109; expression validated by proteogenomic mapping: 40 unique peptides covering 63.4% of sequence
YP_015961.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_015962.1	COG0557; expression validated by proteogenomic mapping: 29 unique peptides covering 35.7% of sequence
YP_015963.1	COG0530; expression validated by proteogenomic mapping: 1 unique peptides covering 3.4% of sequence
YP_015964.1	expression not validated
YP_015965.1	COG0466; expression validated by proteogenomic mapping: 78 unique peptides covering 51.6% of sequence
YP_015966.1	COG4508; expression validated by proteogenomic mapping: 5 unique peptides covering 15.5% of sequence
YP_015967.2	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_015968.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_015969.1	part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_015970.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_015971.1	COG0173; expression validated by proteogenomic mapping: 24 unique peptides covering 42.7% of sequence
YP_015972.1	COG0389; expression validated by proteogenomic mapping: 1 unique peptides covering 2.7% of sequence
YP_015973.1	nicotinic acid mononucleotide adenylyltransferase and HD superfamily hydrolase involved in NAD metabolism; catalyzes the reversible adenylation of nicotinate mononucleotide to nicotinic acid adenine dinucleotide
YP_015974.1	Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_015975.1	expression not validated
YP_015976.1	COG2077; expression validated by proteogenomic mapping: 27 unique peptides covering 71.5% of sequence
YP_015977.1	COG0513; expression validated by proteogenomic mapping: 27 unique peptides covering 34.8% of sequence
YP_015978.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_015979.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_015980.1	COG0610; expression not validated
YP_015981.1	COG0286; expression validated by proteogenomic mapping: 10 unique peptides covering 26.2% of sequence
YP_015982.1	COG0732; expression validated by proteogenomic mapping: 4 unique peptides covering 16.1% of sequence
YP_015983.1	COG0286; expression validated by proteogenomic mapping: 13 unique peptides covering 30.9% of sequence
YP_015984.1	COG0732; expression validated by proteogenomic mapping: 6 unique peptides covering 25.1% of sequence
YP_015985.1	COG0327; expression validated by proteogenomic mapping: 3 unique peptides covering 15% of sequence
YP_015986.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YP_015987.1	COG0531; expression validated by proteogenomic mapping: 2 unique peptides covering 2.6% of sequence
YP_015988.1	COG0358; expression validated by proteogenomic mapping: 3 unique peptides covering 5% of sequence
YP_015989.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_015990.1	COG0580; expression validated by proteogenomic mapping: 1 unique peptides covering 4.3% of sequence
YP_015991.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
YP_015992.1	COG0578; expression validated by proteogenomic mapping: 9 unique peptides covering 35.8% of sequence
YP_015993.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit
YP_015994.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit
YP_015995.1	expression validated by proteogenomic mapping: 9 unique peptides covering 12.9% of sequence
YP_015996.1	expression validated by proteogenomic mapping: 1 unique peptides covering 6.7% of sequence
YP_015997.1	expression validated by proteogenomic mapping: 1 unique peptides covering 5.9% of sequence
YP_015998.1	expression validated by proteogenomic mapping: 7 unique peptides covering 38.5% of sequence
YP_015999.1	expression not validated
YP_016000.1	COG0622; expression validated by proteogenomic mapping: 4 unique peptides covering 26.1% of sequence
YP_016001.1	COG0261; expression validated by proteogenomic mapping: 12 unique peptides covering 64.6% of sequence
YP_016002.1	involved in the peptidyltransferase reaction during translation
YP_016003.1	expression validated by proteogenomic mapping: 6 unique peptides covering 17.6% of sequence
YP_016004.1	expression validated by proteogenomic mapping: 4 unique peptides covering 9.3% of sequence
YP_016005.1	expression validated by proteogenomic mapping: 9 unique peptides covering 38.8% of sequence
YP_016006.1	methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_016007.1	expression validated by proteogenomic mapping: 9 unique peptides covering 18.1% of sequence
YP_016008.1	expression validated by proteogenomic mapping: 71 unique peptides covering 65.6% of sequence
YP_016009.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_016010.1	COG0553; expression validated by proteogenomic mapping: 17 unique peptides covering 20.7% of sequence
YP_016011.1	expression not validated
YP_016012.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_016013.1	possibly phosphorylated; expression validated by proteogenomic mapping: 15 unique peptides covering 11.6% of sequence
YP_016014.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_016015.1	COG3981; expression validated by proteogenomic mapping: 2 unique peptides covering 13.6% of sequence
YP_016016.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_016017.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_016018.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_016019.1	expression validated by proteogenomic mapping: 10 unique peptides covering 20.2% of sequence
YP_016020.1	expression validated by proteogenomic mapping: 59 unique peptides covering 77.2% of sequence
YP_016021.1	expression validated by proteogenomic mapping: 14 unique peptides covering 27.3% of sequence
YP_016022.1	expression validated by proteogenomic mapping: 1 unique peptides covering 8.7% of sequence
YP_016023.1	COG0564; expression validated by proteogenomic mapping: 10 unique peptides covering 30.2% of sequence
YP_016024.1	COG0778; expression validated by proteogenomic mapping: 50 unique peptides covering 77.3% of sequence
YP_016025.1	expression validated by proteogenomic mapping: 40 unique peptides covering 62.2% of sequence
YP_016026.1	expression validated by proteogenomic mapping: 51 unique peptides covering 46.6% of sequence
YP_016027.1	expression validated by proteogenomic mapping: 67 unique peptides covering 55.8% of sequence
YP_016028.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_016029.1	expression not validated
YP_016030.1	expression validated by proteogenomic mapping: 38 unique peptides covering 69.7% of sequence
YP_016031.1	expression validated by proteogenomic mapping: 250 unique peptides covering 73.2% of sequence
YP_016032.1	COG2176; expression validated by proteogenomic mapping: 12 unique peptides covering 36.7% of sequence
YP_016033.1	expression validated by proteogenomic mapping: 18 unique peptides covering 58% of sequence
YP_016034.1	expression validated by proteogenomic mapping: 99 unique peptides covering 68.1% of sequence
YP_016035.1	expression validated by proteogenomic mapping: 7 unique peptides covering 14.2% of sequence
YP_016036.1	expression validated by proteogenomic mapping: 6 unique peptides covering 18.2% of sequence
YP_016037.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_016038.1	expression not validated
YP_016039.1	expression validated by proteogenomic mapping: 5 unique peptides covering 15.9% of sequence
YP_016040.1	possible lipoprotein; COG2333; expression not validated
YP_016041.1	expression validated by proteogenomic mapping: 2 unique peptides covering 12.1% of sequence
YP_016042.1	COG0338; expression validated by proteogenomic mapping: 3 unique peptides covering 11.9% of sequence
YP_016043.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_016044.1	COG0295; expression validated by proteogenomic mapping: 7 unique peptides covering 54.2% of sequence
YP_016045.1	COG0319; expression validated by proteogenomic mapping: 1 unique peptides covering 11.2% of sequence
YP_016046.1	expression not validated
YP_016047.1	COG2274; expression not validated
YP_016048.1	catalyzes the hydrolytic cleavage of the 4'-phosphopantetheine residue from ACP
YP_016049.1	COG1132; expression validated by proteogenomic mapping: 1 unique peptides covering 2.9% of sequence
YP_016050.1	COG0597; expression not validated
YP_016051.1	expression validated by proteogenomic mapping: 1 unique peptides covering 14.1% of sequence
YP_016052.1	COG1323; expression not validated
YP_016053.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_016054.1	COG0558; expression validated by proteogenomic mapping: 1 unique peptides covering 5.4% of sequence
YP_016055.1	expression validated by proteogenomic mapping: 9 unique peptides covering 46.2% of sequence
YP_016056.1	COG1555; expression not validated
YP_016057.1	COG1466; expression validated by proteogenomic mapping: 1 unique peptides covering 3.9% of sequence
YP_016058.1	COG0366; expression validated by proteogenomic mapping: 7 unique peptides covering 19.1% of sequence
YP_016059.1	expression validated by proteogenomic mapping: 24 unique peptides covering 49.5% of sequence
YP_016060.1	expression validated by proteogenomic mapping: 1 unique peptides covering 3.4% of sequence
YP_016061.1	expression not validated
YP_016062.1	COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence
YP_016063.1	expression validated by proteogenomic mapping: 1 unique peptides covering 14.3% of sequence
YP_016064.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_016065.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_016066.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_016067.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_016068.1	COG0009; expression validated by proteogenomic mapping: 7 unique peptides covering 40.7% of sequence
YP_016069.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_016070.1	expression validated by proteogenomic mapping: 14 unique peptides covering 17.6% of sequence
YP_016071.1	COG0758; expression not validated
YP_016072.1	COG1295; expression not validated
YP_016073.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_016074.1	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia
YP_016075.1	COG0721; expression validated by proteogenomic mapping: 3 unique peptides covering 27.5% of sequence
YP_016076.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_016077.1	COG0275; expression validated by proteogenomic mapping: 4 unique peptides covering 14.2% of sequence
YP_016078.1	expression validated by proteogenomic mapping: 2 unique peptides covering 8.1% of sequence
YP_016079.1	expression not validated
YP_016080.1	expression not validated
YP_016081.1	COG0745; expression validated by proteogenomic mapping: 2 unique peptides covering 8.7% of sequence
YP_016082.1	COG2267; expression validated by proteogenomic mapping: 7 unique peptides covering 29.8% of sequence
YP_016083.1	COG0187; expression validated by proteogenomic mapping: 31 unique peptides covering 45% of sequence
YP_016084.1	COG3839; expression validated by proteogenomic mapping: 14 unique peptides covering 44.5% of sequence
YP_016085.1	COG3833; expression not validated
YP_016086.1	COG1175; expression validated by proteogenomic mapping: 1 unique peptides covering 3.7% of sequence
YP_016087.1	expression validated by proteogenomic mapping: 2 unique peptides covering 19.6% of sequence
YP_016088.1	expression not validated
YP_016089.1	C-terminal portion; COG2182; expression validated by proteogenomic mapping: 47 unique peptides covering 51.6% of sequence
YP_016090.1	COG1554; expression not validated
YP_016091.1	N-terminal portion; COG2182; expression validated by proteogenomic mapping: 76 unique peptides covering 72.4% of sequence
YP_016092.1	possible phosphorylase; COG1554; expression validated by proteogenomic mapping: 50 unique peptides covering 47.4% of sequence
YP_016093.1	COG0637; expression validated by proteogenomic mapping: 12 unique peptides covering 41.3% of sequence
YP_016094.1	COG0366; expression validated by proteogenomic mapping: 32 unique peptides covering 51.9% of sequence
YP_016095.1	COG0448; expression validated by proteogenomic mapping: 17 unique peptides covering 45.3% of sequence
YP_016096.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_016097.1	COG1523; expression validated by proteogenomic mapping: 10 unique peptides covering 16.8% of sequence
YP_016098.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_016099.1	COG0297; expression validated by proteogenomic mapping: 14 unique peptides covering 25.6% of sequence
YP_016100.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_016101.1	expression not validated
YP_016102.1	COG0223; expression validated by proteogenomic mapping: 6 unique peptides covering 28.1% of sequence
YP_016103.1	COG1925; expression validated by proteogenomic mapping: 18 unique peptides covering 84.1% of sequence
YP_016104.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_016105.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_016106.1	COG1215; COG0463; expression validated by proteogenomic mapping: 9 unique peptides covering 23.3% of sequence
YP_016107.1	COG1196; expression validated by proteogenomic mapping: 95 unique peptides covering 65.3% of sequence
YP_016108.1	COG0571; expression validated by proteogenomic mapping: 2 unique peptides covering 9.8% of sequence
YP_016109.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_016110.1	related to dihydroxyacetone kinase; COG1461; expression validated by proteogenomic mapping: 36 unique peptides covering 52.6% of sequence
YP_016111.1	expression validated by proteogenomic mapping: 8 unique peptides covering 71.3% of sequence
YP_016112.2	required for 70S ribosome assembly
YP_016113.1	COG3356; expression not validated
YP_016114.1	COG0739; expression validated by proteogenomic mapping: 26 unique peptides covering 53.6% of sequence
YP_016115.1	COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence
YP_016116.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_016117.1	COG0562; expression validated by proteogenomic mapping: 29 unique peptides covering 60.3% of sequence
YP_016118.1	COG0463; expression validated by proteogenomic mapping: 6 unique peptides covering 18.4% of sequence
YP_016119.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_016120.1	expression validated by proteogenomic mapping: 20 unique peptides covering 65% of sequence
YP_016121.1	expression not validated
YP_016122.1	similar to M. hyopneumoniae P65; expression validated by proteogenomic mapping: 27 unique peptides covering 22.9% of sequence
YP_016123.1	COG0168; expression validated by proteogenomic mapping: 1 unique peptides covering 1.9% of sequence
YP_016124.1	COG0569; expression validated by proteogenomic mapping: 12 unique peptides covering 40.8% of sequence
YP_016125.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_016126.1	COG0336; expression validated by proteogenomic mapping: 9 unique peptides covering 40.2% of sequence
YP_016127.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_016128.1	COG0619; expression validated by proteogenomic mapping: 2 unique peptides covering 6.9% of sequence
YP_016129.1	with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene
YP_016130.1	with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene
YP_016131.1	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively
YP_016132.1	COG0782; expression validated by proteogenomic mapping: 23 unique peptides covering 87.9% of sequence
YP_016133.1	expression validated by proteogenomic mapping: 4 unique peptides covering 19.3% of sequence
YP_016134.1	expression validated by proteogenomic mapping: 3 unique peptides covering 22.5% of sequence
YP_016135.1	COG0816; expression not validated
YP_016136.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_016137.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_016138.1	expression validated by proteogenomic mapping: 78 unique peptides covering 58% of sequence
YP_016139.1	expression validated by proteogenomic mapping: 35 unique peptides covering 47.9% of sequence
YP_016140.1	possibly interacts with ftsH; COG0670; expression not validated
YP_016141.1	COG1481; expression validated by proteogenomic mapping: 1 unique peptides covering 5.3% of sequence
YP_016142.1	COG3763; expression validated by proteogenomic mapping: 1 unique peptides covering 14.7% of sequence
YP_016143.1	COG0640; expression validated by proteogenomic mapping: 13 unique peptides covering 78.7% of sequence
YP_016144.1	expression not validated
YP_016145.1	COG1123; expression validated by proteogenomic mapping: 17 unique peptides covering 24.9% of sequence
YP_016146.1	N-terminal phosphoglycerate kinase domain and C-terminal oligopeptide ABC transporter ATPase domain; COG0126; COG0444; expression validated by proteogenomic mapping: 29 unique peptides covering 39.3% of sequence
YP_016147.1	COG1173; expression validated by proteogenomic mapping: 4 unique peptides covering 11.2% of sequence
YP_016148.1	COG0601; expression validated by proteogenomic mapping: 2 unique peptides covering 6.3% of sequence
YP_016149.1	expression validated by proteogenomic mapping: 58 unique peptides covering 66.2% of sequence
YP_016150.1	COG0126; expression validated by proteogenomic mapping: 74 unique peptides covering 76.3% of sequence
YP_016151.1	expression validated by proteogenomic mapping: 51 unique peptides covering 67% of sequence
YP_016152.1	COG1624; expression validated by proteogenomic mapping: 6 unique peptides covering 23.1% of sequence
YP_016153.1	COG1502; expression validated by proteogenomic mapping: 1 unique peptides covering 3.6% of sequence
YP_016154.1	COG2059; expression not validated
YP_016155.1	COG2059; expression not validated
YP_016156.1	possibly protein prenyltransferase; expression validated by proteogenomic mapping: 3 unique peptides covering 8.2% of sequence
YP_016157.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_016158.1	COG2189; expression validated by proteogenomic mapping: 24 unique peptides covering 39.2% of sequence
YP_016159.1	COG1061; expression validated by proteogenomic mapping: 21 unique peptides covering 34% of sequence
YP_016160.1	COG0260; expression validated by proteogenomic mapping: 59 unique peptides covering 85.2% of sequence
YP_016161.1	COG1264; COG1263; expression validated by proteogenomic mapping: 4 unique peptides covering 5.8% of sequence
YP_016162.1	COG1621; expression validated by proteogenomic mapping: 12 unique peptides covering 16.2% of sequence
YP_016163.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_016164.1	COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence
YP_016165.1	COG0196; expression validated by proteogenomic mapping: 3 unique peptides covering 13.5% of sequence
YP_016166.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_016167.1	expression not validated
YP_016168.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_016169.1	COG1281; expression validated by proteogenomic mapping: 7 unique peptides covering 28.3% of sequence
YP_016170.1	expression validated by proteogenomic mapping: 3 unique peptides covering 26% of sequence
YP_016171.1	COG1216; expression validated by proteogenomic mapping: 1 unique peptides covering 10.3% of sequence
YP_016172.1	COG0564; expression validated by proteogenomic mapping: 5 unique peptides covering 22% of sequence
YP_016173.1	contains HTH motif; functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer
YP_016174.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB
YP_016175.1	COG0204; expression validated by proteogenomic mapping: 11 unique peptides covering 33.3% of sequence
YP_016176.1	COG0736; expression not validated
YP_016177.1	functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC
YP_016178.1	COG0776; expression validated by proteogenomic mapping: 11 unique peptides covering 55.6% of sequence
YP_016179.1	COG0240; expression validated by proteogenomic mapping: 17 unique peptides covering 54.7% of sequence
YP_016180.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_016181.1	COG0283; expression validated by proteogenomic mapping: 15 unique peptides covering 30% of sequence
YP_016182.1	COG0484; expression validated by proteogenomic mapping: 36 unique peptides covering 60.6% of sequence
YP_016183.1	expression validated by proteogenomic mapping: 41 unique peptides covering 97.3% of sequence
YP_016184.1	catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.
YP_016185.1	COG0258; expression validated by proteogenomic mapping: 13 unique peptides covering 33.9% of sequence
YP_016186.1	COG0210; expression validated by proteogenomic mapping: 7 unique peptides covering 14% of sequence
YP_016187.1	expression validated by proteogenomic mapping: 5 unique peptides covering 10.2% of sequence
YP_016188.1	COG0210; expression validated by proteogenomic mapping: 32 unique peptides covering 44.1% of sequence
YP_016189.1	expression not validated
YP_016190.1	expression validated by proteogenomic mapping: 11 unique peptides covering 31% of sequence
YP_016191.1	negatively supercoils closed circular double-stranded DNA
YP_016192.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
YP_016193.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_016194.1	contains EF-hand Ca++ binding domain and zinc protease signature sequence; expression validated by proteogenomic mapping: 22 unique peptides covering 43.9% of sequence
YP_016195.1	COG3557; expression validated by proteogenomic mapping: 4 unique peptides covering 18% of sequence
YP_016196.1	COG1112; expression validated by proteogenomic mapping: 43 unique peptides covering 40.1% of sequence
YP_016197.1	expression validated by proteogenomic mapping: 4 unique peptides covering 27.9% of sequence
YP_016198.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_016199.1	related to tRNA (uracil-5-)-methyltransferase; COG2265; expression validated by proteogenomic mapping: 5 unique peptides covering 17.9% of sequence
YP_016200.1	expression validated by proteogenomic mapping: 22 unique peptides covering 71.9% of sequence
YP_016201.1	expression validated by proteogenomic mapping: 6 unique peptides covering 59.5% of sequence
YP_016202.1	expression validated by proteogenomic mapping: 2 unique peptides covering 13.5% of sequence
YP_016203.1	COG0515; expression validated by proteogenomic mapping: 10 unique peptides covering 18.3% of sequence
YP_016204.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_016205.1	expression validated by proteogenomic mapping: 12 unique peptides covering 42.3% of sequence
YP_016206.1	expression validated by proteogenomic mapping: 16 unique peptides covering 51.1% of sequence
YP_016207.1	COG1132; expression validated by proteogenomic mapping: 18 unique peptides covering 33.8% of sequence
YP_016208.1	COG1132; expression validated by proteogenomic mapping: 11 unique peptides covering 27% of sequence
YP_016209.1	expression not validated
YP_016210.1	expression validated by proteogenomic mapping: 2 unique peptides covering 5.5% of sequence
YP_016211.1	COG1692; expression validated by proteogenomic mapping: 14 unique peptides covering 56.6% of sequence
YP_016212.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_016213.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_016214.2	related to the helicase subunit of the Holliday junction resolvase; COG2256; expression validated by proteogenomic mapping: 4 unique peptides covering 13.2% of sequence
YP_016215.1	COG1451; expression not validated
YP_016216.1	expression validated by proteogenomic mapping: 8 unique peptides covering 26.7% of sequence
YP_016217.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_016218.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_016219.1	COG2755; expression validated by proteogenomic mapping: 8 unique peptides covering 9.9% of sequence
YP_016220.1	COG2077; expression validated by proteogenomic mapping: 2 unique peptides covering 17.7% of sequence
YP_016221.1	COG1109; expression validated by proteogenomic mapping: 3 unique peptides covering 5.2% of sequence
YP_016222.1	COG0313; expression validated by proteogenomic mapping: 8 unique peptides covering 43.2% of sequence
YP_016223.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_016224.1	COG0541; expression validated by proteogenomic mapping: 21 unique peptides covering 37.8% of sequence
YP_016225.1	COG1482; expression validated by proteogenomic mapping: 15 unique peptides covering 43.3% of sequence
YP_016226.1	COG1322; expression validated by proteogenomic mapping: 19 unique peptides covering 56.5% of sequence
YP_016227.1	COG2131; expression validated by proteogenomic mapping: 8 unique peptides covering 51.9% of sequence
YP_016228.1	putative tRNA binding domain protein; COG0073; expression validated by proteogenomic mapping: 4 unique peptides covering 20.7% of sequence
YP_016229.1	COG1307; expression validated by proteogenomic mapping: 28 unique peptides covering 67.8% of sequence
YP_016230.1	COG0244; expression validated by proteogenomic mapping: 14 unique peptides covering 74.3% of sequence
YP_016231.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_016232.1	COG0813; expression validated by proteogenomic mapping: 28 unique peptides covering 69.1% of sequence
YP_016233.1	COG0213; expression validated by proteogenomic mapping: 44 unique peptides covering 64.9% of sequence
YP_016234.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
YP_016235.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_016236.1	COG0495; expression validated by proteogenomic mapping: 18 unique peptides covering 37.5% of sequence
YP_016237.1	COG0465; expression validated by proteogenomic mapping: 55 unique peptides covering 48.7% of sequence
YP_016238.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_016239.1	COG0783; expression validated by proteogenomic mapping: 20 unique peptides covering 79% of sequence
YP_016240.1	expression validated by proteogenomic mapping: 33 unique peptides covering 63.8% of sequence
YP_016241.1	expression validated by proteogenomic mapping: 9 unique peptides covering 44.5% of sequence
YP_016242.1	COG0322; expression validated by proteogenomic mapping: 7 unique peptides covering 17% of sequence
YP_016243.1	expression validated by proteogenomic mapping: 46 unique peptides covering 50.7% of sequence
YP_016244.1	COG0162; expression validated by proteogenomic mapping: 5 unique peptides covering 18.6% of sequence
YP_016245.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
YP_016246.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif
YP_016247.1	COG0006; expression validated by proteogenomic mapping: 26 unique peptides covering 63.6% of sequence
YP_016248.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_016249.1	expression not validated
YP_016250.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_016251.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_016252.1	COG0539; expression validated by proteogenomic mapping: 2 unique peptides covering 16.4% of sequence
YP_016253.1	COG0742; expression validated by proteogenomic mapping: 7 unique peptides covering 47.3% of sequence
YP_016254.1	Essential for recycling GMP and indirectly, cGMP
YP_016255.1	COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence
YP_016256.1	COG0515; expression validated by proteogenomic mapping: 27 unique peptides covering 51.8% of sequence
YP_016257.1	COG1162; expression validated by proteogenomic mapping: 6 unique peptides covering 40.6% of sequence
YP_016258.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_016259.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_016260.1	COG0084; expression validated by proteogenomic mapping: 3 unique peptides covering 14.2% of sequence
YP_016261.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_016262.1	expression validated by proteogenomic mapping: 15 unique peptides covering 61.1% of sequence
YP_016263.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_016264.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_016265.1	catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_016266.1	expression validated by proteogenomic mapping: 3 unique peptides covering 33% of sequence
YP_016267.1	possibly Asp/Glu racemase; expression validated by proteogenomic mapping: 5 unique peptides covering 39.4% of sequence
YP_016268.1	COG0526; expression validated by proteogenomic mapping: 9 unique peptides covering 70.7% of sequence
YP_016269.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_016270.1	expression validated by proteogenomic mapping: 17 unique peptides covering 22.6% of sequence
YP_016271.1	COG1704; expression validated by proteogenomic mapping: 24 unique peptides covering 61.9% of sequence
YP_016272.1	expression validated by proteogenomic mapping: 11 unique peptides covering 32% of sequence
YP_016273.1	COG0669; expression validated by proteogenomic mapping: 4 unique peptides covering 32.4% of sequence
YP_016274.1	COG0237; expression not validated
YP_016275.1	catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine
YP_016276.1	COG0451; expression validated by proteogenomic mapping: 48 unique peptides covering 79.4% of sequence
YP_016277.1	COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence
YP_016278.1	COG0508; expression validated by proteogenomic mapping: 78 unique peptides covering 80.1% of sequence
YP_016279.1	unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain
YP_016280.1	COG0022; expression validated by proteogenomic mapping: 56 unique peptides covering 71.8% of sequence
YP_016281.1	COG1071; expression validated by proteogenomic mapping: 90 unique peptides covering 89.7% of sequence
YP_016282.1	COG3022; expression not validated
YP_016283.1	COG4095; expression validated by proteogenomic mapping: 4 unique peptides covering 22.9% of sequence
YP_016284.1	COG4095; expression validated by proteogenomic mapping: 4 unique peptides covering 18.9% of sequence
YP_016285.1	expression validated by proteogenomic mapping: 14 unique peptides covering 76.1% of sequence
YP_016286.1	COG0693; expression validated by proteogenomic mapping: 5 unique peptides covering 26.9% of sequence
YP_016287.1	expression not validated
YP_016288.1	homolog of Bvg accessory factor; COG1521; expression validated by proteogenomic mapping: 3 unique peptides covering 18.1% of sequence
YP_016289.1	COG0452; expression validated by proteogenomic mapping: 11 unique peptides covering 30% of sequence
YP_016290.1	involved in LPS biosynthesis; COG0510; expression validated by proteogenomic mapping: 5 unique peptides covering 23.2% of sequence
YP_016291.1	expression validated by proteogenomic mapping: 7 unique peptides covering 22.6% of sequence
YP_016292.1	expression validated by proteogenomic mapping: 18 unique peptides covering 35.6% of sequence
YP_016293.1	expression validated by proteogenomic mapping: 2 unique peptides covering 4.5% of sequence
YP_016294.1	COG0807; expression validated by proteogenomic mapping: 9 unique peptides covering 20.4% of sequence
YP_016295.1	expression validated by proteogenomic mapping: 7 unique peptides covering 11.3% of sequence
YP_016296.1	expression not validated
YP_016297.1	expression not validated
YP_016298.1	COG1004; expression validated by proteogenomic mapping: 8 unique peptides covering 25% of sequence
YP_016299.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_016300.1	COG1881; expression validated by proteogenomic mapping: 81 unique peptides covering 74.6% of sequence
YP_016301.1	expression validated by proteogenomic mapping: 12 unique peptides covering 63.6% of sequence
YP_016302.1	expression validated by proteogenomic mapping: 13 unique peptides covering 58.4% of sequence
YP_016303.1	COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence
YP_016304.1	expression validated by proteogenomic mapping: 20 unique peptides covering 72.7% of sequence
YP_016305.1	expression validated by proteogenomic mapping: 18 unique peptides covering 34.4% of sequence
YP_016306.1	expression validated by proteogenomic mapping: 24 unique peptides covering 33.2% of sequence
YP_016307.1	expression validated by proteogenomic mapping: 1 unique peptides covering 2.4% of sequence
YP_016308.1	expression validated by proteogenomic mapping: 1 unique peptides covering 4.8% of sequence
YP_016309.1	COG1479; expression not validated
YP_016310.1	expression not validated
YP_016311.1	expression validated by proteogenomic mapping: 4 unique peptides covering 7.1% of sequence
YP_016312.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
YP_016313.1	expression validated by proteogenomic mapping: 3 unique peptides covering 11.2% of sequence
YP_016314.1	COG0242; expression validated by proteogenomic mapping: 11 unique peptides covering 64.1% of sequence
YP_016315.1	metallo-beta-lactamase superfamily or serine protease; COG0595; expression validated by proteogenomic mapping: 20 unique peptides covering 29.5% of sequence
YP_016316.1	COG1970; expression validated by proteogenomic mapping: 6 unique peptides covering 23.2% of sequence
YP_016317.1	COG0446; expression validated by proteogenomic mapping: 70 unique peptides covering 81% of sequence
YP_016318.1	metallo-beta-lactamase superfamily; COG0595; expression validated by proteogenomic mapping: 17 unique peptides covering 33.9% of sequence
YP_016319.1	expression validated by proteogenomic mapping: 21 unique peptides covering 36.8% of sequence
YP_016320.1	COG0488; expression validated by proteogenomic mapping: 39 unique peptides covering 47.4% of sequence
YP_016321.1	COG0164; expression not validated
YP_016322.1	COG4095; expression validated by proteogenomic mapping: 1 unique peptides covering 12.1% of sequence
YP_016323.1	COG4095; expression validated by proteogenomic mapping: 3 unique peptides covering 12% of sequence
YP_016324.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_016325.1	COG0291; expression validated by proteogenomic mapping: 3 unique peptides covering 18.5% of sequence
YP_016326.1	COG0290; expression validated by proteogenomic mapping: 21 unique peptides covering 66.8% of sequence
YP_016327.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_016328.1	COG0594; expression not validated
YP_016329.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_016330.1	expression validated by proteogenomic mapping: 14 unique peptides covering 55.9% of sequence