-- dump date 20120504_153511 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_325832.1 15828472 911526 222..1607 1 NC_002771.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1607 dnaA 911526 dnaA Mycoplasma pulmonis UAB CTIP chromosome replication initiator DnaA NP_325832.1 222 D 272635 CDS NP_325833.1 15828473 911279 1741..2862 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P34029 (DP3B_SPICI) Blastp2 P=3e-14 C=43%; DNA polymerase III, beta chain 2862 911279 MYPU_0020 Mycoplasma pulmonis UAB CTIP DNA polymerase III, beta chain NP_325833.1 1741 D 272635 CDS NP_325834.1 15828474 911490 2864..3085 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P05650 (YAAA_BACSU) Blastp2 P=6e-06 C=45%; hypothetical protein 3085 911490 MYPU_0030 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325834.1 2864 D 272635 CDS NP_325835.1 15828475 911272 3088..3771 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P43055 (YLI1_MYCHO) Blastp2 P=1e-28 C=53%; hypothetical protein 3771 911272 MYPU_0040 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325835.1 3088 D 272635 CDS NP_325836.1 15828476 911577 complement(3778..4422) 1 NC_002771.1 no similarity found; hypothetical protein 4422 911577 MYPU_0050 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325836.1 3778 R 272635 CDS NP_325837.1 15828477 911316 4603..6759 1 NC_002771.1 no similarity found; hypothetical protein 6759 911316 MYPU_0060 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325837.1 4603 D 272635 CDS NP_325838.1 15828478 911338 6759..8189 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q49557 (Q49557) Blastp2 P=3e-15 C=29% pfscan: pos. 18-28 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 8189 911338 MYPU_0070 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325838.1 6759 D 272635 CDS NP_325839.1 15828479 911586 8190..8540 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P32083 (YHIT_MYCHR) Blastp2 P=7e-22 C=56%; HIT-like protein (cell cycle regulation) 8540 911586 MYPU_0080 Mycoplasma pulmonis UAB CTIP HIT-like protein (cell cycle regulation) NP_325839.1 8190 D 272635 CDS NP_325840.2 161723295 911649 8703..9296 1 NC_002771.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L14 9296 rplK 911649 rplK Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L14 NP_325840.2 8703 D 272635 CDS NP_325841.1 15828481 911580 9296..9985 1 NC_002771.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 9985 rplA 911580 rplA Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L1 NP_325841.1 9296 D 272635 CDS NP_325842.1 15828482 911524 complement(10940..12316) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q07380 (Q07380) Blastp2 P=9e-06 C=37%; hypothetical protein 12316 911524 MYPU_0110 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325842.1 10940 R 272635 CDS NP_325843.1 15828483 911315 complement(12519..13205) 1 NC_002771.1 no similarity found; hypothetical protein 13205 911315 MYPU_0120 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325843.1 12519 R 272635 CDS NP_325844.1 15828484 911626 13293..14621 1 NC_002771.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 14621 trmE 911626 trmE Mycoplasma pulmonis UAB CTIP tRNA modification GTPase TrmE NP_325844.1 13293 D 272635 CDS NP_325845.1 15828485 911675 14667..15425 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P37545 (YABD_BACSU) Blastp2 P=7e-41 C=60% ScanProsite: PDOC00836 PS01090 UPF0006_2 Uncharacterized protein family UPF0006 signature 2 122-132 PVIIHCRETFD; hypothetical protein 15425 911675 MYPU_0140 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325845.1 14667 D 272635 CDS NP_325846.1 15828486 911546 15426..16184 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P43038 (KSGA_MYCCA) Blastp2 P=8e-48 C=63%; dimethyladenosine transferase 16184 911546 MYPU_0150 Mycoplasma pulmonis UAB CTIP dimethyladenosine transferase NP_325846.1 15426 D 272635 CDS NP_325847.1 15828487 911509 16188..16547 1 NC_002771.1 no similarity found; hypothetical protein 16547 911509 MYPU_0160 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325847.1 16188 D 272635 CDS NP_325848.1 15828488 911420 16711..19086 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P20166 (PTGA_BACSU) Blastp2 P=9e-64 C=29% Pfscan: pos. 656-765 PF00358 | PTS_EIIA_1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PDO pos. 531-565 PF00367 | PTS_EIIB phosphotransferase system, EIIB (PDOC00795) pos. 686-738 GC0246 | PTS_EII_EIII_1 PTS EII/EIII components phosphorylation site sig pos. 706-718 PS00371 | PTS_EIIA_1 PTS EIIA domains phosphorylation site signature 1; PTS system, glucose-specific IIABC component (EIIABC-glc) (glucose-permease IIABC component) (phosphotransferase enzyme II, ABC component)(EII-glc/EIII-glc) 19086 911420 MYPU_0170 Mycoplasma pulmonis UAB CTIP PTS system, glucose-specific IIABC component (EIIABC-glc) (glucose-permease IIABC component) (phosphotransferase enzyme II, ABC component)(EII-glc/EIII-glc) NP_325848.1 16711 D 272635 CDS NP_325849.1 15828489 911693 19400..20608 1 NC_002771.1 identified by sequence similarity; identical to Genbank:Z16416 pos.54-1259 ; Bhugra,B. and Dybvig,K.; Identification and characterization of IS1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); IS1138 transposase 20608 911693 MYPU_0180 Mycoplasma pulmonis UAB CTIP IS1138 transposase NP_325849.1 19400 D 272635 CDS NP_325850.1 15828490 911368 21109..23409 1 NC_002771.1 no similarity found ProfileScan: pos.11-21 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; polymorphism located in the promoter (21062 pb): six sequences with (T)31 and 2 sequences with (T)29; lipoprotein 23409 911368 MYPU_0190 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325850.1 21109 D 272635 CDS NP_325851.1 15828491 910954 24591..24950 1 NC_002771.1 no similarity found; hypothetical protein 24950 910954 MYPU_0200 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325851.1 24591 D 272635 CDS NP_325852.1 15828492 911502 25127..26494 1 NC_002771.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 26494 911502 MYPU_0210 Mycoplasma pulmonis UAB CTIP dihydrolipoamide dehydrogenase NP_325852.1 25127 D 272635 CDS NP_325853.1 15828493 911352 26515..27489 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P22746 (MGPA_MYCGE) Blastp2 P=6e-59 C=57% Pfscan: pos. 12-315 PF01368 | DHH DHH family ; Sperker, B. et al., 1991. Molecular Microbiology. 5:299-306. Inamine, I. et al., 1988. Gene. 73:175-183.; hypothetical protein 27489 911352 MYPU_0220 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325853.1 26515 D 272635 CDS NP_325854.1 15828494 911276 27742..29178 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75389 (NAOX_MYCPN) Blastp2 P=0 C=62%; NADH oxidase 29178 911276 MYPU_0230 Mycoplasma pulmonis UAB CTIP NADH oxidase NP_325854.1 27742 D 272635 CDS NP_325855.1 15828495 911323 29335..31866 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:P75489 Blastp2 P=9e-60 score=232 Pfscan: pos.12-22 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 31866 911323 MYPU_0240 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325855.1 29335 D 272635 CDS NP_325856.1 15828496 911328 31869..32639 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47432 (Y186_MYCGE) Blastp2 P=1e-17 C=42% pfscan: pos.15-25 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 32639 911328 MYPU_0250 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325856.1 31869 D 272635 CDS NP_325857.1 15828497 911547 32643..34445 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P47433 (Y187_MYCGE) Blastp2 P=0 C=61% Pfscan: pos. 60-85 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 384-456 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 58-460 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 362-415 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family pos. 65-72 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 384-398 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 34445 911547 MYPU_0260 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_325857.1 32643 D 272635 CDS NP_325858.1 15828498 911600 34385..35449 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75263 (Y188_MYCPN) Blastp2 P=2e-77 C=57% Pfscan: pos. 220-299 PF00528 | BPD_TRANSP Binding-protein-dependent transport systems inner membrane component (PDOC pos. 210-268 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inne; ABC transporter permease 35449 911600 MYPU_0270 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_325858.1 34385 D 272635 CDS NP_325859.2 229270470 911436 35409..36392 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75262 (Y189_MYCPN) Blastp2 P=2e-78 C=64% Pfscan: pos. 202-277 PF00528 | BPD_TRANSP Binding-protein-dependent transport systems inner membrane component (PDOC pos. 194-251 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inne pos. 203-231 PS00402 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inner membrane comp. sign; ABC transporter permease 36392 911436 MYPU_0280 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_325859.2 35409 D 272635 CDS NP_325860.1 15828500 911596 36397..36582 1 NC_002771.1 no similarity found; hypothetical protein 36582 911596 MYPU_0290 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325860.1 36397 D 272635 CDS NP_325861.1 15828501 911575 36626..37114 1 NC_002771.1 no similarity found; hypothetical protein 37114 911575 MYPU_0300 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325861.1 36626 D 272635 CDS NP_325862.1 15828502 911429 37419..37742 1 NC_002771.1 no similarity found; hypothetical protein 37742 911429 MYPU_0310 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325862.1 37419 D 272635 CDS NP_325863.1 15828503 911433 37708..38745 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75394 (LPLA_MYCPN) Blastp2 P=5e-67 C=58%; lipoate-protein ligase A 38745 911433 MYPU_0320 Mycoplasma pulmonis UAB CTIP lipoate-protein ligase A NP_325863.1 37708 D 272635 CDS NP_325864.1 15828504 911593 38663..39535 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q49418 (ESL2_MYCGE) Blastp2 P=4e-09 C=37%; esterase 39535 911593 MYPU_0330 Mycoplasma pulmonis UAB CTIP esterase NP_325864.1 38663 D 272635 CDS NP_325865.1 15828505 911664 39561..40826 1 NC_002771.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 40826 911664 MYPU_0340 Mycoplasma pulmonis UAB CTIP seryl-tRNA synthetase NP_325865.1 39561 D 272635 CDS NP_325866.1 15828506 911280 40826..41632 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75333 (ESL1_MYCPN) Blastp2 P=2e-34 C=51%; esterase 41632 911280 MYPU_0350 Mycoplasma pulmonis UAB CTIP esterase NP_325866.1 40826 D 272635 CDS NP_325867.1 15828507 911484 41636..42457 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75333 (ESL1_MYCPN) Blastp2 P=2e-26 C=47%; esterase 42457 911484 MYPU_0360 Mycoplasma pulmonis UAB CTIP esterase NP_325867.1 41636 D 272635 CDS NP_325868.1 15828508 911539 42461..43282 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75333 (ESL1_MYCPN) Blastp2 P=4e-25 C=44%; esterase 43282 911539 MYPU_0370 Mycoplasma pulmonis UAB CTIP esterase NP_325868.1 42461 D 272635 CDS NP_325869.1 15828509 911587 43306..44109 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75333 (ESL1_MYCPN) Blastp2 P=1e-27 C=45%; esterase 44109 911587 MYPU_0380 Mycoplasma pulmonis UAB CTIP esterase NP_325869.1 43306 D 272635 CDS NP_325870.1 15828510 911430 44365..45990 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P44407 (MSBA_HAEIN) Blastp2 P=3e-18 C=21% Pfscan: pos. 358-376 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 457-526 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 356-530 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 436-488 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 363-370 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); ABC transporter ATP-binding protein 45990 911430 MYPU_0390 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_325870.1 44365 D 272635 CDS NP_325871.1 15828511 911585 45965..46684 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q49521 (Q49521) Blastp2 P=2e-07 C=40%; ABC transporter permease 46684 911585 MYPU_0400 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_325871.1 45965 D 272635 CDS NP_325872.1 15828512 911642 46741..47580 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P55469 (Y4GM_RHISN) Blastp2 P=4e-13 C=30% Pfscan: pos. 95-116 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 201-259 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 93-275 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 171-232 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 100-107 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 201-215 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 47580 911642 MYPU_0410 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_325872.1 46741 D 272635 CDS NP_325873.1 15828513 911604 complement(47605..48831) 1 NC_002771.1 identified by sequence similarity; similar to trEMBL:AAF06072 Blastp2 P=5e-20 score=99.1; hypothetical protein 48831 911604 MYPU_0420 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325873.1 47605 R 272635 CDS NP_325874.1 15828514 911340 complement(48813..49703) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P15840 (MTSI_SPISQ) Blastp2 P=5e-46 C=51%; CpG DNA methylase 49703 911340 MYPU_0430 Mycoplasma pulmonis UAB CTIP CpG DNA methylase NP_325874.1 48813 R 272635 CDS NP_325875.1 15828515 911310 complement(49651..50031) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P15840 (MTSI_SPISQ) Blastp2 P=7e-12 C=51%; CpG DNA methylase 50031 911310 MYPU_0440 Mycoplasma pulmonis UAB CTIP CpG DNA methylase NP_325875.1 49651 R 272635 CDS NP_325876.1 15828516 911667 50136..51005 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O67890 (FMT_AQUAE) Blastp2 P=2e-43 C=49%; methionyl-tRNA formyltransferase 51005 911667 MYPU_0450 Mycoplasma pulmonis UAB CTIP methionyl-tRNA formyltransferase NP_325876.1 50136 D 272635 CDS NP_325877.1 15828517 911286 51034..52083 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75358 (G3P_MYCPN) Blastp2 P=0 C=69%; glyceraldehyde 3-phosphate dehydrogenase 52083 911286 MYPU_0460 Mycoplasma pulmonis UAB CTIP glyceraldehyde 3-phosphate dehydrogenase NP_325877.1 51034 D 272635 CDS NP_325878.1 15828518 911656 complement(52127..52393) 1 NC_002771.1 no similarity found; hypothetical protein 52393 911656 MYPU_0470 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325878.1 52127 R 272635 CDS NP_325879.1 15828519 911528 52206..53144 1 NC_002771.1 no similarity found; hypothetical protein 53144 911528 MYPU_0480 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325879.1 52206 D 272635 CDS NP_325880.1 15828520 911405 53235..55745 1 NC_002771.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 55745 911405 MYPU_0490 Mycoplasma pulmonis UAB CTIP DNA polymerase III subunits gamma and tau NP_325880.1 53235 D 272635 CDS NP_325881.1 15828521 911428 55738..56040 1 NC_002771.1 identified by sequence similarity; similar to trEMBL:Q9ZCA0 Blastp2 P=7e-05 score=46; hypothetical protein 56040 911428 MYPU_0500 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325881.1 55738 D 272635 CDS NP_325882.1 15828522 911579 56053..56628 1 NC_002771.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 56628 recR 911579 recR Mycoplasma pulmonis UAB CTIP recombination protein RecR NP_325882.1 56053 D 272635 CDS NP_325883.1 15828523 911421 56612..57316 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P37537 (KTHY_BACSU) Blastp2 P=3e-29 C=50%; thymidylate kinase 57316 911421 MYPU_0520 Mycoplasma pulmonis UAB CTIP thymidylate kinase NP_325883.1 56612 D 272635 CDS NP_325884.1 15828524 911285 57333..58226 1 NC_002771.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 58226 911285 MYPU_0530 Mycoplasma pulmonis UAB CTIP DNA polymerase III subunit delta' NP_325884.1 57333 D 272635 CDS NP_325885.1 15828525 911558 58219..58887 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISSPROT:P45298 Blastp2 P=6e-36 C==55% ; Pfscan: pos.3-202 PF00590 | TP_METHYLASE Tetrapyrrole (Corrin/Porphyrin) Methylases. (PDOC00656); hypothetical protein 58887 911558 MYPU_0540 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325885.1 58219 D 272635 CDS NP_325886.1 15828526 911648 complement(59090..60787) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P22848 (5NTD_VIBPA) Blastp2 P=5e-36 C=42%; 5'-nucleotidase 60787 911648 MYPU_0550 Mycoplasma pulmonis UAB CTIP 5'-nucleotidase NP_325886.1 59090 R 272635 CDS NP_325887.1 15828527 911271 complement(60793..61215) 1 NC_002771.1 identified by sequence similarity; similar to TrEMBL:O53103 Blastp2 P=0.018 score=38.7 Pfscan: pos.17-27 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 61215 911271 MYPU_0560 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325887.1 60793 R 272635 CDS NP_325888.1 15828528 911439 61414..62598 1 NC_002771.1 no similarity found Pfscan: pos.15-25 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 62598 911439 MYPU_0570 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325888.1 61414 D 272635 CDS NP_325889.1 15828529 911454 63374..64582 1 NC_002771.1 no similarity found; hypothetical protein 64582 911454 MYPU_0580 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325889.1 63374 D 272635 CDS NP_325890.1 15828530 911602 64840..65739 1 NC_002771.1 no similarity found; hypothetical protein 65739 911602 MYPU_0590 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325890.1 64840 D 272635 CDS NP_325891.1 15828531 911622 65724..66644 1 NC_002771.1 no similarity found; hypothetical protein 66644 911622 MYPU_0600 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325891.1 65724 D 272635 CDS NP_325892.1 15828532 911457 67316..67741 1 NC_002771.1 no similarity found; hypothetical protein 67741 911457 MYPU_0610 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325892.1 67316 D 272635 CDS NP_325893.1 15828533 911566 67762..68730 1 NC_002771.1 no similarity found; hypothetical protein 68730 911566 MYPU_0620 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325893.1 67762 D 272635 CDS NP_325894.1 15828534 911706 68967..69518 1 NC_002771.1 no similarity found; hypothetical protein 69518 911706 MYPU_0630 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325894.1 68967 D 272635 CDS NP_325895.1 15828535 911297 69521..70018 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P45022 (GLTL_HAEIN) Blastp2 P=2e-18 C=49% Pfscan: pos. 29-47 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 133-165 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 27-165 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 111-164 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 34- 41 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 133-147 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 70018 911297 MYPU_0640 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_325895.1 69521 D 272635 CDS NP_325896.1 15828536 911681 70034..71458 1 NC_002771.1 no similarity found; TMpred prediction: 4 transmembrane helices; ABC transporter permease 71458 911681 MYPU_0650 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_325896.1 70034 D 272635 CDS NP_325897.1 15828537 911496 71473..73752 1 NC_002771.1 identified by sequence similarity; unknown; similar to SWISS-PROT:P47705 (Y467_MYCGE) Blastp2 P=1e-23 C=13% Pfscan: pos. 29-48 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 134-204 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 27-208 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 112-165 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 34-41 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 134-148 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 73752 911496 MYPU_0660 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_325897.1 71473 D 272635 CDS NP_325898.1 15828538 911467 74114..74914 1 NC_002771.1 no similarity found Pfscan: pos. 17-27 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site pos. 192-206 PS00165 | DEHYDRATASE_SER_THR Serine/threonine dehydratases pyridoxal-phosphate attachment site; lipoprotein 74914 911467 MYPU_0670 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325898.1 74114 D 272635 CDS NP_325899.1 15828539 911491 complement(75081..76010) 1 NC_002771.1 identified by sequence similarity; similar to trEMBL:AAF09169 Blastp2 P=2e-55 score=215 Pfscan: pos.13-202 PF01145 | BAND_7 Band 7 family (PDOC00977); hypothetical protein 76010 911491 MYPU_0680 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325899.1 75081 R 272635 CDS NP_325900.1 15828540 911721 76135..77577 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P23304 (DEAD_ECOLI) Blastp2 P=2e-67 C=42%; ATP-dependent RNA helicase 77577 911721 MYPU_0690 Mycoplasma pulmonis UAB CTIP ATP-dependent RNA helicase NP_325900.1 76135 D 272635 CDS NP_325901.1 15828541 911535 complement(78401..78607) 1 NC_002771.1 no similarity found; hypothetical protein 78607 911535 MYPU_0700 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325901.1 78401 R 272635 CDS NP_325902.1 15828542 911595 79639..79824 1 NC_002771.1 no similarity found; hypothetical protein 79824 911595 MYPU_0710 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325902.1 79639 D 272635 CDS NP_325903.1 15828543 911684 79960..80127 1 NC_002771.1 no similarity found; hypothetical protein 80127 911684 MYPU_0720 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325903.1 79960 D 272635 CDS NP_325904.1 15828544 911556 complement(80311..81006) 1 NC_002771.1 no similarity found; hypothetical protein 81006 911556 MYPU_0730 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325904.1 80311 R 272635 CDS NP_325905.1 15828545 911308 complement(81360..81602) 1 NC_002771.1 no similarity found; hypothetical protein 81602 911308 MYPU_0740 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325905.1 81360 R 272635 CDS NP_325906.1 15828546 911291 81640..81792 1 NC_002771.1 no similarity found; hypothetical protein 81792 911291 MYPU_0750 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325906.1 81640 D 272635 CDS NP_325907.1 15828547 911544 82641..82829 1 NC_002771.1 no similarity found; hypothetical protein 82829 911544 MYPU_0760 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325907.1 82641 D 272635 CDS NP_325908.1 15828548 910921 82741..83655 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O05052 Blastp2 P=2e-34 Id=35% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit R3 (fragment) 83655 910921 MYPU_0770 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit R3 (fragment) NP_325908.1 82741 D 272635 CDS NP_325909.1 15828549 911614 83710..84849 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O05052 Blastp2 P=3e-51 Id=33% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit R3 (fragment) 84849 911614 MYPU_0780 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit R3 (fragment) NP_325909.1 83710 D 272635 CDS NP_325910.1 15828550 911275 complement(85156..85482) 1 NC_002771.1 no similarity found; hypothetical protein 85482 911275 MYPU_0790 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325910.1 85156 R 272635 CDS NP_325911.1 15828551 911336 85553..85828 1 NC_002771.1 no similarity found; hypothetical protein 85828 911336 MYPU_0800 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325911.1 85553 D 272635 CDS NP_325912.1 15828552 911294 85856..86239 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O33298 (O33298) Blastp2 P=3e-09 C=52% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit M3 (fragment) 86239 911294 MYPU_0810 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit M3 (fragment) NP_325912.1 85856 D 272635 CDS NP_325913.1 15828553 911707 86433..87431 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O33298 Blastp2 P=2e-56 Id=39% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit M3 (fragment) 87431 911707 MYPU_0820 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit M3 (fragment) NP_325913.1 86433 D 272635 CDS NP_325914.1 15828554 911710 87468..88547 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50356 Blastp2 P=6e-14 Id=37% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit S3A 88547 911710 MYPU_0830 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit S3A NP_325914.1 87468 D 272635 CDS NP_325915.1 15828555 911273 complement(88549..89595) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9ZL54 (Q9ZL54) Blastp2 P=9e-19 C=27% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit S3B 89595 911273 MYPU_0840 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit S3B NP_325915.1 88549 R 272635 CDS NP_325916.1 15828556 911282 complement(89890..90381) 1 NC_002771.1 no similarity found; hypothetical protein 90381 911282 MYPU_0850 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325916.1 89890 R 272635 CDS NP_325917.1 15828557 911278 90469..90942 1 NC_002771.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 90942 recU 911278 recU Mycoplasma pulmonis UAB CTIP Holliday junction-specific endonuclease NP_325917.1 90469 D 272635 CDS NP_325918.1 15828558 910919 complement(90932..91312) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P36206 (DBH_THEMA) Blastp2 P=8e-13 C=45%; DNA-binding protein HU 91312 910919 MYPU_0870 Mycoplasma pulmonis UAB CTIP DNA-binding protein HU NP_325918.1 90932 R 272635 CDS NP_325919.1 15828559 911724 complement(91276..92583) 1 NC_002771.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 92583 engA 911724 engA Mycoplasma pulmonis UAB CTIP GTP-binding protein EngA NP_325919.1 91276 R 272635 CDS NP_325920.1 15828560 911418 complement(92561..93232) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P38493 (KCY_BACSU) Blastp2 P=8e-30 C=58%; cytidylate kinase 93232 911418 MYPU_0890 Mycoplasma pulmonis UAB CTIP cytidylate kinase NP_325920.1 92561 R 272635 CDS NP_325921.1 15828561 911674 complement(93239..93670) 1 NC_002771.1 no similarity found; hypothetical protein 93670 911674 MYPU_0900 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325921.1 93239 R 272635 CDS NP_325922.1 15828562 911327 complement(93745..93864) 1 NC_002771.1 no similarity found; hypothetical protein 93864 911327 MYPU_0910 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325922.1 93745 R 272635 CDS NP_325923.1 15828563 911615 93935..95749 1 NC_002771.1 no similarity found; Pfscan: pos. 15-25 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 95749 911615 MYPU_0920 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325923.1 93935 D 272635 CDS NP_325924.1 15828564 911597 complement(95918..98341) 1 NC_002771.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 98341 leuS 911597 leuS Mycoplasma pulmonis UAB CTIP leucyl-tRNA synthetase NP_325924.1 95918 R 272635 CDS NP_325925.1 15828565 910924 98487..99620 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O35046 (YOCD_BACSU) Blastp2 P=1e-23 C=39%; hypothetical protein 99620 910924 MYPU_0940 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325925.1 98487 D 272635 CDS NP_325926.1 15828566 911301 99647..100783 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q10627 (OGT_MYCTU) Blastp2 P=5e-28 C=19%; methylated-DNA--protein-cysteine methyltransferase 100783 911301 MYPU_0950 Mycoplasma pulmonis UAB CTIP methylated-DNA--protein-cysteine methyltransferase NP_325926.1 99647 D 272635 CDS NP_325927.1 15828567 911623 complement(100778..102751) 1 NC_002771.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 102751 911623 MYPU_0960 Mycoplasma pulmonis UAB CTIP excinuclease ABC subunit B NP_325927.1 100778 R 272635 CDS NP_325928.1 15828568 911339 102808..103257 1 NC_002771.1 catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-CoA; phosphopantetheine adenylyltransferase 103257 coaD 911339 coaD Mycoplasma pulmonis UAB CTIP phosphopantetheine adenylyltransferase NP_325928.1 102808 D 272635 CDS NP_325929.1 15828569 910916 complement(103276..104730) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q46443 (Q46443) Blastp2 P=6e-14 C=38% Pfscan: pos. 15-25 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; sugar ABC transporter 104730 910916 MYPU_0980 Mycoplasma pulmonis UAB CTIP sugar ABC transporter NP_325929.1 103276 R 272635 CDS NP_325930.1 15828570 911395 complement(104711..106471) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P94360 (MSMX_BACSU) Blastp2 P=6e-52 C=26% Pfscan: pos. 64-89 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 292-364 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 62-368 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 270-323 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 69-76 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 292-306 PS00211 | ABC_TRANSPORTER ABC transporters family signature; sugar ABC transporter ATP-binding protein 106471 911395 MYPU_0990 Mycoplasma pulmonis UAB CTIP sugar ABC transporter ATP-binding protein NP_325930.1 104711 R 272635 CDS NP_325931.1 15828571 911525 complement(106472..107338) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P37729 (AMYC_THETU) Blastp2 P=2e-36 C=45% Pfscan: pos. 170-243 PF00528 | BPD_TRANSP Binding-protein-dependent transport systems inner membrane component pos. 160-219 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inner membrane comp. sign pos. 171-199 PS00402 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inner membrane comp. sign; sugar ABC transporter permease 107338 911525 MYPU_1000 Mycoplasma pulmonis UAB CTIP sugar ABC transporter permease NP_325931.1 106472 R 272635 CDS NP_325932.1 15828572 911268 complement(107338..108189) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P37730 (AMYD_THETU) Blastp2 P=1e-39 C=49% Pfscan: pos. 168-240 PF00528 | BPD_TRANSP Binding-protein-dependent transport systems inner membrane component pos. 158-217 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inner membrane comp. sign pos. 169-197 PS00402 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inner membrane comp. sign; sugar ABC transporter permease 108189 911268 MYPU_1010 Mycoplasma pulmonis UAB CTIP sugar ABC transporter permease NP_325932.1 107338 R 272635 CDS NP_325933.1 15828573 911307 108035..108208 1 NC_002771.1 no similarity found; hypothetical protein 108208 911307 MYPU_1020 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325933.1 108035 D 272635 CDS NP_325934.1 15828574 911685 complement(108191..109825) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P29094 (O16G_BACTR) Blastp2 P=5e-93 C=55%; oligo-1,6-glucosidase 109825 911685 MYPU_1030 Mycoplasma pulmonis UAB CTIP oligo-1,6-glucosidase NP_325934.1 108191 R 272635 CDS NP_325935.1 15828575 911601 complement(110535..113138) 1 NC_002771.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 113138 secA 911601 secA Mycoplasma pulmonis UAB CTIP preprotein translocase subunit SecA NP_325935.1 110535 R 272635 CDS NP_325936.1 15828576 911333 113289..114368 1 NC_002771.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 114368 prfA 911333 prfA Mycoplasma pulmonis UAB CTIP peptide chain release factor 1 NP_325936.1 113289 D 272635 CDS NP_325937.1 15828577 911645 114368..115060 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P45873 (HEMK_BACSU) Blastp2 P=1e-16 C=48%; protoporphirogen oxidase HEMK 115060 911645 MYPU_1060 Mycoplasma pulmonis UAB CTIP protoporphirogen oxidase HEMK NP_325937.1 114368 D 272635 CDS NP_325938.1 15828578 911715 115139..115792 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P15361 (P29_MYCHR) Blastp2 P=2e-22 C=48%; ABC transporter ATP-binding protein 115792 911715 MYPU_1070 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_325938.1 115139 D 272635 CDS NP_325939.1 15828579 911718 115795..117501 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P15362 (P69_MYCHR) Blastp2 P=7e-30 C=38%; ABC transporter permease 117501 911718 MYPU_1080 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_325939.1 115795 D 272635 CDS NP_325940.1 15828580 911293 117538..118638 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47681 (Y443_MYCGE) Blastp2 P=1e-07 C=35% Tmpred prediction: 6 transmembrane helices; ABC transporter permease 118638 911293 MYPU_1090 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_325940.1 117538 D 272635 CDS NP_325941.1 15828581 911366 complement(118832..119692) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75089 (ALF_MYCPN) Blastp2 P=3e-81 C=68%; fructose-bisphosphate aldolase 119692 911366 MYPU_1100 Mycoplasma pulmonis UAB CTIP fructose-bisphosphate aldolase NP_325941.1 118832 R 272635 CDS NP_325942.1 15828582 910922 119779..120486 1 NC_002771.1 no similarity found; hypothetical protein 120486 910922 MYPU_1110 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325942.1 119779 D 272635 CDS NP_325943.1 15828583 911590 120522..121436 1 NC_002771.1 identified by sequence similarity; similar to trEMBL:Q50289 (Y185_MYCPN) Blast2p P=5e-5 score=48.8; hypothetical protein 121436 911590 MYPU_1120 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325943.1 120522 D 272635 CDS NP_325944.1 15828584 911690 121494..121820 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P75480 (ACPS_MYCPN) Blastp2 P=6e-07 C=49%; holo-ACP synthase 121820 911690 MYPU_1130 Mycoplasma pulmonis UAB CTIP holo-ACP synthase NP_325944.1 121494 D 272635 CDS NP_325945.1 15828585 911274 121805..122572 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75479 (PLSC_MYCPN) Blastp2 P=2e-24 C=48%; 1-acyl-sn-glycerol-3-phosphate acyltransferase 122572 911274 MYPU_1140 Mycoplasma pulmonis UAB CTIP 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_325945.1 121805 D 272635 CDS NP_325946.1 15828586 911376 122572..123321 1 NC_002771.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 123321 scpA 911376 scpA Mycoplasma pulmonis UAB CTIP segregation and condensation protein A NP_325946.1 122572 D 272635 CDS NP_325947.1 15828587 911303 123278..123901 1 NC_002771.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 123901 scpB 911303 scpB Mycoplasma pulmonis UAB CTIP segregation and condensation protein B NP_325947.1 123278 D 272635 CDS NP_325948.1 15828588 911475 123902..124750 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9X038 Blastp2 P=5e-24 score=111 Pfscan: pos. 84-236 PF00849 | YABO Hypothetical yabO/yceC/sfhB family (PDOC00869) (PDOC00885); pseudouridylate synthase 124750 911475 MYPU_1170 Mycoplasma pulmonis UAB CTIP pseudouridylate synthase NP_325948.1 123902 D 272635 CDS NP_325949.1 15828589 911722 complement(124755..125663) 1 NC_002771.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 125663 911722 MYPU_1180 Mycoplasma pulmonis UAB CTIP DNA-binding/iron metalloprotein/AP endonuclease NP_325949.1 124755 R 272635 CDS NP_325950.1 15828590 911296 complement(125657..126199) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O66494 (O66494) Blastp2 P=1e-06 C=50%; hypothetical protein 126199 911296 MYPU_1190 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325950.1 125657 R 272635 CDS NP_325951.1 15828591 911288 complement(126193..126585) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O52749 (YJEE_ANASP) Blastp2 P=1e-11 C=46% Pfscan: pos. 33-40 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 126585 911288 MYPU_1200 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325951.1 126193 R 272635 CDS NP_325952.1 15828592 911679 126668..127405 1 NC_002771.1 no similarity found; hypothetical protein 127405 911679 MYPU_1210 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325952.1 126668 D 272635 CDS NP_325953.1 15828593 911699 complement(127394..130477) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P75033 (Y140_MYCPN) Blastp2 P=5e-35 C=21%; ATP-binding protein 130477 911699 MYPU_1220 Mycoplasma pulmonis UAB CTIP ATP-binding protein NP_325953.1 127394 R 272635 CDS NP_325954.1 15828594 911450 130454..130861 1 NC_002771.1 no similarity found; hypothetical protein 130861 911450 MYPU_1230 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325954.1 130454 D 272635 CDS NP_325955.1 15828595 911599 complement(130919..131890) 1 NC_002771.1 [NAD+]; identified by sequence similarity; possible; similar to SWISS-PROT:P46919 (GPDA_BACSU) Blastp2 P=2e-28 C=48%; glycerol-3-phosphate dehydrogenase 131890 911599 MYPU_1240 Mycoplasma pulmonis UAB CTIP glycerol-3-phosphate dehydrogenase NP_325955.1 130919 R 272635 CDS NP_325956.1 15828596 911298 complement(131900..133543) 1 NC_002771.1 no similarity found; hypothetical protein 133543 911298 MYPU_1250 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325956.1 131900 R 272635 CDS NP_325957.1 15828597 911374 133641..134294 1 NC_002771.1 no similarity found; hypothetical protein 134294 911374 MYPU_1260 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325957.1 133641 D 272635 CDS NP_325958.1 15828598 911401 134388..135353 1 NC_002771.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 135353 911401 MYPU_1270 Mycoplasma pulmonis UAB CTIP ribose-phosphate pyrophosphokinase NP_325958.1 134388 D 272635 CDS NP_325959.1 15828599 910925 135362..136045 1 NC_002771.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 136045 gidB 910925 gidB Mycoplasma pulmonis UAB CTIP 16S rRNA methyltransferase GidB NP_325959.1 135362 D 272635 CDS NP_325960.1 15828600 910923 136184..138280 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47308 (PTFA_MYCGE) Blastp2 P=0 C=54% Pfscan: pos. 25-68 PF00359 | PTS_EIIA_2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS system, fructose-specific IIABC component (EIIABC-fru) (fructose-permease IIABC component)(phosphotransferase enzyme II, ABC component) (EII-fru/EIII-fru) 138280 910923 MYPU_1290 Mycoplasma pulmonis UAB CTIP PTS system, fructose-specific IIABC component (EIIABC-fru) (fructose-permease IIABC component)(phosphotransferase enzyme II, ABC component) (EII-fru/EIII-fru) NP_325960.1 136184 D 272635 CDS NP_325961.1 15828601 910913 138517..138852 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P56008(RS1_HELPY) Blast2p P=0.001 score=42.2 Pfscan: pos. 4-73 PS50126 | S1 S1-motif (ribosomal); 30S ribosomal protein S1 138852 910913 MYPU_1300 Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S1 NP_325961.1 138517 D 272635 CDS NP_325962.1 15828602 911650 138840..140123 1 NC_002771.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 140123 pgi 911650 pgi Mycoplasma pulmonis UAB CTIP glucose-6-phosphate isomerase NP_325962.1 138840 D 272635 CDS NP_325963.1 15828603 911321 complement(140124..141275) 1 NC_002771.1 no similarity found; hypothetical protein 141275 911321 MYPU_1320 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325963.1 140124 R 272635 CDS NP_325964.1 15828604 911578 complement(141347..143086) 1 NC_002771.1 no similarity found; hypothetical protein 143086 911578 MYPU_1330 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325964.1 141347 R 272635 CDS NP_325965.1 15828605 910947 143984..144133 1 NC_002771.1 no similarity found; hypothetical protein 144133 910947 MYPU_1340 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325965.1 143984 D 272635 CDS NP_325966.1 15828606 910944 145185..145574 1 NC_002771.1 no similarity found; hypothetical protein 145574 910944 MYPU_1350 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325966.1 145185 D 272635 CDS NP_325967.1 15828607 911683 145565..146011 1 NC_002771.1 no similarity found; hypothetical protein 146011 911683 MYPU_1360 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325967.1 145565 D 272635 CDS NP_325968.1 15828608 911370 complement(146064..146777) 1 NC_002771.1 identified by sequence similarity; similar to TrEMBL:O87952 Blastp2 P=1e-19 score=97 Pfscan: pos. 1-78 PS00430 | TONB_DEPENDENT_REC_1 TonB-dependent receptor proteins signature 1; potassium uptake protein KTRA 146777 911370 MYPU_1370 Mycoplasma pulmonis UAB CTIP potassium uptake protein KTRA NP_325968.1 146064 R 272635 CDS NP_325969.1 15828609 911598 146940..147743 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:P96741 (P96741) Blastp2 P=2e-08 C=21% Pfscan: pos. 7-248 PF00592 | DUF3 Domain of Unknown Function 3; hypothetical protein 147743 911598 MYPU_1380 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325969.1 146940 D 272635 CDS NP_325970.1 15828610 911334 148199..148771 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O58971 (O58971) Blastp2 P=7e-08 C=33% Pfscan: pos. 38-178 PF00565 | SNASE Staphylococcal nuclease homologues pos. 21-31 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site pos. 91-136 GC0349 | ISOCITRATE_LYASE Isocitrate lyase signature; nuclease, lipoprotein 148771 911334 MYPU_1390 Mycoplasma pulmonis UAB CTIP nuclease, lipoprotein NP_325970.1 148199 D 272635 CDS NP_325971.1 15828611 911704 148881..149090 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P56053 (RL31_HELPY) Blastp2 P=1e-10 C=60%; 50S ribosomal protein L31 149090 911704 MYPU_1400 Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L31 NP_325971.1 148881 D 272635 CDS NP_325972.1 15828612 911365 149111..149737 1 NC_002771.1 no similarity found; hypothetical protein 149737 911365 MYPU_1410 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325972.1 149111 D 272635 CDS NP_325973.1 15828613 911686 149781..150824 1 NC_002771.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 150824 hrcA 911686 hrcA Mycoplasma pulmonis UAB CTIP heat-inducible transcription repressor NP_325973.1 149781 D 272635 CDS NP_325974.1 15828614 911638 150772..151668 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P48604 (GRPE_DROME) Blastp2 P=3e-08 C=24%; heat shock protein GrpE 151668 911638 MYPU_1430 Mycoplasma pulmonis UAB CTIP heat shock protein GrpE NP_325974.1 150772 D 272635 CDS NP_325975.1 15828615 910929 complement(151889..153460) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:O67474 Blastp2 P=1e-19 score=131 Pfscan: pos. 154-161 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); potassium uptake protein KTRB 153460 910929 MYPU_1440 Mycoplasma pulmonis UAB CTIP potassium uptake protein KTRB NP_325975.1 151889 R 272635 CDS NP_325976.1 15828616 911300 complement(153539..154111) 1 NC_002771.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 154111 911300 MYPU_1450 Mycoplasma pulmonis UAB CTIP thymidine kinase NP_325976.1 153539 R 272635 CDS NP_325977.1 15828617 910926 154324..154551 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q49310 (Y33A_MYCGE) Blastp2 P=1e-08 C=62%; hypothetical protein 154551 910926 MYPU_1460 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325977.1 154324 D 272635 CDS NP_325978.1 15828618 911651 154669..157332 1 NC_002771.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 157332 911651 MYPU_1470 Mycoplasma pulmonis UAB CTIP DNA gyrase subunit A NP_325978.1 154669 D 272635 CDS NP_325979.1 15828619 911348 157622..158605 1 NC_002771.1 no similarity found; hypothetical protein 158605 911348 MYPU_1480 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325979.1 157622 D 272635 CDS NP_325980.1 15828620 910927 158608..160002 1 NC_002771.1 no similarity found; hypothetical protein 160002 910927 MYPU_1490 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325980.1 158608 D 272635 CDS NP_325981.1 15828621 911440 159992..160432 1 NC_002771.1 no similarity found; hypothetical protein 160432 911440 MYPU_1500 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325981.1 159992 D 272635 CDS NP_325982.1 15828622 911689 160490..160726 1 NC_002771.1 identified by sequence similarity ; similar to Genbank:Z16416 pos 880-1113; Bhugra,B. and Dybvig,K. ; Identification and characterization of IS1138, a transposable element from Mycoplasma p ulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); truncated IS1138 transposase 160726 911689 MYPU_1510 Mycoplasma pulmonis UAB CTIP truncated IS1138 transposase NP_325982.1 160490 D 272635 CDS NP_325983.1 15828623 911304 complement(161053..162879) 1 NC_002771.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 162879 911304 MYPU_1520 Mycoplasma pulmonis UAB CTIP inner membrane protein translocase component YidC NP_325983.1 161053 R 272635 CDS NP_325984.1 15828624 911540 complement(162863..163198) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P43039 (RNPA_MYCCA) Blastp2 P=2e-11 C=55%; ribonuclease P protein component (protein C5) (RNase P) 163198 911540 MYPU_1530 Mycoplasma pulmonis UAB CTIP ribonuclease P protein component (protein C5) (RNase P) NP_325984.1 162863 R 272635 CDS NP_325985.1 15828625 911588 complement(163226..163372) 1 NC_002771.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 163372 rpmH 911588 rpmH Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L34 NP_325985.1 163226 R 272635 CDS NP_325986.1 15828626 910943 complement(163592..166381) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47317 (ATCL_MYCGE) Blastp2 P=0 C=49% Pfscan: pos. 96-746 PF00122 | E1_E2_ATPASE E1-E2 ATPases (PDOC00139) pos. 322-370 GC0337 | ATPASE_E1_E2 E1-E2 ATPases phosphorylation site. pos. 342-348 PS00154 | ATPASE_E1_E2 E1-E2 ATPases phosphorylation site; cation-transporting P-type ATPase 166381 910943 MYPU_1550 Mycoplasma pulmonis UAB CTIP cation-transporting P-type ATPase NP_325986.1 163592 R 272635 CDS NP_325987.1 15828627 910948 complement(166445..168136) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P14951 (UVRC_BACSU) Blastp2 P=2e-63 C=49%; excinuclease ABC subunit C 168136 910948 MYPU_1560 Mycoplasma pulmonis UAB CTIP excinuclease ABC subunit C NP_325987.1 166445 R 272635 CDS NP_325988.1 15828628 911269 complement(168172..168588) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P43313 (NAPA_HELPY) Blastp2 P=1e-11 C=51%; neutrophil-activating protein A (NAP A) (bacterioferritin) 168588 911269 MYPU_1570 Mycoplasma pulmonis UAB CTIP neutrophil-activating protein A (NAP A) (bacterioferritin) NP_325988.1 168172 R 272635 CDS NP_325989.1 15828629 911415 168751..170730 1 NC_002771.1 no similarity found ; Pfscan: pos. 22-32 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 170730 911415 MYPU_1580 Mycoplasma pulmonis UAB CTIP lipoprotein NP_325989.1 168751 D 272635 CDS NP_325990.1 15828630 911270 170734..171420 1 NC_002771.1 no similarity found; hypothetical protein 171420 911270 MYPU_1590 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325990.1 170734 D 272635 CDS NP_325991.1 15828631 911570 171389..171748 1 NC_002771.1 no similarity found; hypothetical protein 171748 911570 MYPU_1600 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325991.1 171389 D 272635 CDS NP_325992.1 15828632 911367 171735..173372 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47609 (Y369_MYCGE) Blastp2 P=7e-75 C=53%; hypothetical protein 173372 911367 MYPU_1610 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325992.1 171735 D 272635 CDS NP_325993.1 15828633 911583 173375..174352 1 NC_002771.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 174352 911583 MYPU_1620 Mycoplasma pulmonis UAB CTIP glycerol-3-phosphate acyltransferase PlsX NP_325993.1 173375 D 272635 CDS NP_325994.1 15828634 911627 174352..175077 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P51833 (RNC_BACSU) Blastp2 P=4e-28 C=52%, polymorphism position 174457 bp: 5 sequences with G(A)7CA(T)8C, 1 sequence with G(A)7CA(T)7C, 1 sequence with G(A)8CA(T)8C; ribonuclease III (RNase III) 175077 911627 MYPU_1630 Mycoplasma pulmonis UAB CTIP ribonuclease III (RNase III) NP_325994.1 174352 D 272635 CDS NP_325995.1 15828635 911701 complement(175074..175232) 1 NC_002771.1 no similarity found; hypothetical protein 175232 911701 MYPU_1640 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325995.1 175074 R 272635 CDS NP_325996.1 15828636 911312 complement(175287..176396) 1 NC_002771.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 176396 911312 MYPU_1650 Mycoplasma pulmonis UAB CTIP GTP-dependent nucleic acid-binding protein EngD NP_325996.1 175287 R 272635 CDS NP_325997.1 15828637 911277 complement(176405..177016) 1 NC_002771.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 177016 trmB 911277 trmB Mycoplasma pulmonis UAB CTIP tRNA (guanine-N(7)-)-methyltransferase NP_325997.1 176405 R 272635 CDS NP_325998.1 15828638 911427 177117..177632 1 NC_002771.1 no similarity found; hypothetical protein 177632 911427 MYPU_1670 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_325998.1 177117 D 272635 CDS NP_325999.1 15828639 911265 177598..178215 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47360 (PGSA_MYCGE) Blastp2 P=1e-29 C=58%; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase 178215 911265 MYPU_1680 Mycoplasma pulmonis UAB CTIP CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase NP_325999.1 177598 D 272635 CDS NP_326000.1 15828640 911431 178224..178706 1 NC_002771.1 no similarity found; hypothetical protein 178706 911431 MYPU_1690 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326000.1 178224 D 272635 CDS NP_326001.1 15828641 911594 178669..179124 1 NC_002771.1 no similarity found; hypothetical protein 179124 911594 MYPU_1700 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326001.1 178669 D 272635 CDS NP_326002.1 15828642 911573 179125..179841 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:Q06803 (HLYA_TREHY) Blastp2 P=9e-36 C=58%; hemolysin A 179841 911573 MYPU_1710 Mycoplasma pulmonis UAB CTIP hemolysin A NP_326002.1 179125 D 272635 CDS NP_326003.1 15828643 911363 179810..180991 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q49420 (NISH_MYCGE) Blastp2 P=2e-37 C=47%; nitrogen fixation protein NifS 180991 911363 MYPU_1720 Mycoplasma pulmonis UAB CTIP nitrogen fixation protein NifS NP_326003.1 179810 D 272635 CDS NP_326004.1 15828644 911463 181083..182246 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q49420 (NISH_MYCGE) Blastp2 P=4e-48 C=49%; nitrogen fixation protein NifS 182246 911463 MYPU_1730 Mycoplasma pulmonis UAB CTIP nitrogen fixation protein NifS NP_326004.1 181083 D 272635 CDS NP_326005.1 15828645 911574 182323..182757 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:O32163 (O32163) Blastp2 P=3e-13 C=51%; nitrogen fixation protein NIFU 182757 911574 MYPU_1740 Mycoplasma pulmonis UAB CTIP nitrogen fixation protein NIFU NP_326005.1 182323 D 272635 CDS NP_326006.1 15828646 911435 complement(182835..183050) 1 NC_002771.1 no similarity found; hypothetical protein 183050 911435 MYPU_1750 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326006.1 182835 R 272635 CDS NP_326007.1 15828647 911498 183224..185101 1 NC_002771.1 no similarity found Pfscan: pos. 160-169 PS00142 | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature; hypothetical protein 185101 911498 MYPU_1760 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326007.1 183224 D 272635 CDS NP_326008.1 15828648 911666 185128..186918 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47495 (SYC_MYCGE) Blastp2 P=3e-63 C=36%; cysteinyl-tRNA synthetase 186918 911666 MYPU_1770 Mycoplasma pulmonis UAB CTIP cysteinyl-tRNA synthetase NP_326008.1 185128 D 272635 CDS NP_326009.1 15828649 911584 186977..187666 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q06753 (YACO_BACSU) Blastp2 P=7e-33 C=56%; tRNA/rRNA methyltransferase 187666 911584 MYPU_1780 Mycoplasma pulmonis UAB CTIP tRNA/rRNA methyltransferase NP_326009.1 186977 D 272635 CDS NP_326010.1 15828650 911592 187617..188240 1 NC_002771.1 no similarity found; hypothetical protein 188240 911592 MYPU_1790 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326010.1 187617 D 272635 CDS NP_326011.1 15828651 911631 188281..188421 1 NC_002771.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 188421 rpmG 911631 rpmG Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L33 NP_326011.1 188281 D 272635 CDS NP_326012.1 15828652 911330 188385..188654 1 NC_002771.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 188654 secE 911330 secE Mycoplasma pulmonis UAB CTIP preprotein translocase subunit SecE NP_326012.1 188385 D 272635 CDS NP_326013.1 15828653 911495 188654..189244 1 NC_002771.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 189244 nusG 911495 nusG Mycoplasma pulmonis UAB CTIP transcription antitermination protein NusG NP_326013.1 188654 D 272635 CDS NP_326014.1 15828654 911669 189494..190999 1 NC_002771.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 190999 911669 MYPU_1830 Mycoplasma pulmonis UAB CTIP prolyl-tRNA synthetase NP_326014.1 189494 D 272635 CDS NP_326015.1 15828655 911456 191149..191526 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P14949 (THIO_BACSU) Blastp2 P=8e-11 C=41%; thioredoxin 191526 911456 MYPU_1840 Mycoplasma pulmonis UAB CTIP thioredoxin NP_326015.1 191149 D 272635 CDS NP_326016.1 15828656 911646 191656..191904 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P15840 (MTSI_SPISQ) Blastp2 P=2e-06 C=40%; CpG DNA methylase (cytosine-specific methyltransferase SSSI) 191904 911646 MYPU_1850 Mycoplasma pulmonis UAB CTIP CpG DNA methylase (cytosine-specific methyltransferase SSSI) NP_326016.1 191656 D 272635 CDS NP_326017.1 15828657 911659 192158..192952 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P15840 (MTSI_SPISQ) Blastp2 P=4e-22 C=44%; CpG DNA methylase (cytosine-specific methyltransferase SSSI) 192952 911659 MYPU_1860 Mycoplasma pulmonis UAB CTIP CpG DNA methylase (cytosine-specific methyltransferase SSSI) NP_326017.1 192158 D 272635 CDS NP_326018.1 15828658 911411 192921..195812 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9ZLW4 (Q9ZLW4) Blastp2 P=3e-08 C=25%; hypothetical protein 195812 911411 MYPU_1870 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326018.1 192921 D 272635 CDS NP_326019.1 15828659 911582 195900..197177 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P54545 (YQJH_BACSU) Blastp2 P=1e-46 C=46% Pfscan: pos.14-195 PS50173 | UMUC_DOMAIN UMUC domain (DNA-repair) pos.17-355 PF00817 | IMS impB/mucB/samB family; DNA-damage repair protein MucB 197177 911582 MYPU_1880 Mycoplasma pulmonis UAB CTIP DNA-damage repair protein MucB NP_326019.1 195900 D 272635 CDS NP_326020.1 15828660 911671 complement(197185..197574) 1 NC_002771.1 no similarity found; hypothetical protein 197574 911671 MYPU_1890 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326020.1 197185 R 272635 CDS NP_326021.1 15828661 911581 197201..197590 1 NC_002771.1 no similarity found; hypothetical protein 197590 911581 MYPU_1900 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326021.1 197201 D 272635 CDS NP_326022.1 15828662 911342 complement(197567..198037) 1 NC_002771.1 no similarity found; hypothetical protein 198037 911342 MYPU_1910 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326022.1 197567 R 272635 CDS NP_326023.1 15828663 911438 complement(198037..198540) 1 NC_002771.1 no similarity found; hypothetical protein 198540 911438 MYPU_1920 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326023.1 198037 R 272635 CDS NP_326024.1 15828664 911563 complement(198755..199726) 1 NC_002771.1 no similarity found Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 199726 911563 MYPU_1930 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326024.1 198755 R 272635 CDS NP_326025.1 15828665 911356 complement(199719..200561) 1 NC_002771.1 no similarity found Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 200561 911356 MYPU_1940 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326025.1 199719 R 272635 CDS NP_326026.1 15828666 910912 complement(200548..201510) 1 NC_002771.1 no similarity found Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 201510 910912 MYPU_1950 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326026.1 200548 R 272635 CDS NP_326027.1 15828667 911267 complement(201485..202192) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75444 (YF02_MYCPN) Blastp2 P=2e-55 C=64% Pfscan: pos. 136-207 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 32-211 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 114-167 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 39-46 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 136-150 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 202192 911267 MYPU_1960 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_326027.1 201485 R 272635 CDS NP_326028.1 15828668 911460 complement(202192..204012) 1 NC_002771.1 no similarity found; hypothetical protein 204012 911460 MYPU_1970 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326028.1 202192 R 272635 CDS NP_326029.1 15828669 911311 204437..206392 1 NC_002771.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunits IICB 206392 ulaA 911311 ulaA Mycoplasma pulmonis UAB CTIP PTS system ascorbate-specific transporter subunits IICB NP_326029.1 204437 D 272635 CDS NP_326030.1 15828670 911672 206594..206899 1 NC_002771.1 no similarity found; hypothetical protein 206899 911672 MYPU_1990 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326030.1 206594 D 272635 CDS NP_326031.1 15828671 911605 206868..208214 1 NC_002771.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 208214 911605 MYPU_2000 Mycoplasma pulmonis UAB CTIP amidase NP_326031.1 206868 D 272635 CDS NP_326032.1 15828672 911635 208144..209628 1 NC_002771.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 209628 gatB 911635 gatB Mycoplasma pulmonis UAB CTIP aspartyl/glutamyl-tRNA amidotransferase subunit B NP_326032.1 208144 D 272635 CDS NP_326033.1 15828673 911653 209628..210686 1 NC_002771.1 no similarity found; hypothetical protein 210686 911653 MYPU_2020 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326033.1 209628 D 272635 CDS NP_326034.1 15828674 911287 210850..212502 1 NC_002771.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 212502 nusA 911287 nusA Mycoplasma pulmonis UAB CTIP transcription elongation factor NusA NP_326034.1 210850 D 272635 CDS NP_326035.1 15828675 911437 212477..212788 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P32728 (YLXR_BACSU) Blastp2 P=5e-06 C=43%; hypothetical protein 212788 911437 MYPU_2040 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326035.1 212477 D 272635 CDS NP_326036.1 15828676 911591 212761..214572 1 NC_002771.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 214572 infB 911591 infB Mycoplasma pulmonis UAB CTIP translation initiation factor IF-2 NP_326036.1 212761 D 272635 CDS NP_326037.1 15828677 910918 complement(214692..217013) 1 NC_002771.1 no similarity found Pfscan: pos. 16-26 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 217013 910918 MYPU_2060 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326037.1 214692 R 272635 CDS NP_326038.1 15828678 911567 complement(217170..218873) 1 NC_002771.1 no similarity found Pfscan: pos. 6-16 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 218873 911567 MYPU_2070 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326038.1 217170 R 272635 CDS NP_326039.1 15828679 911434 complement(219224..219376) 1 NC_002771.1 no similarity found; hypothetical protein 219376 911434 MYPU_2080 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326039.1 219224 R 272635 CDS NP_326040.1 15828680 911289 219705..221084 1 NC_002771.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 221084 tig 911289 tig Mycoplasma pulmonis UAB CTIP trigger factor NP_326040.1 219705 D 272635 CDS NP_326041.1 15828681 911569 221077..221241 1 NC_002771.1 no similarity found; hypothetical protein 221241 911569 MYPU_2100 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326041.1 221077 D 272635 CDS NP_326042.1 15828682 910920 221649..231299 1 NC_002771.1 no similarity found; hypothetical protein 231299 910920 MYPU_2110 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326042.1 221649 D 272635 CDS NP_326043.1 15828683 911477 231322..235455 1 NC_002771.1 no similarity found Pfscan: pos. 1022-1029 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 235455 911477 MYPU_2120 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326043.1 231322 D 272635 CDS NP_326044.1 15828684 911309 235289..240175 1 NC_002771.1 no similarity found; polymorphism position 240173 : T/G inducing a frameshift in the CDS MYPU_2130/MYPU_2140; hypothetical protein 240175 911309 MYPU_2130 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326044.1 235289 D 272635 CDS NP_326045.1 15828685 911644 240662..244471 1 NC_002771.1 no similarity found; Pfscan: pos. 606-613 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); polymorphism position 240173 : T/G inducing a frameshift in the CDS MYPU_2130/MYPU_2140; hypothetical protein 244471 911644 MYPU_2140 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326045.1 240662 D 272635 CDS NP_326046.1 15828686 911576 complement(244537..244704) 1 NC_002771.1 no similarity found; hypothetical protein 244704 911576 MYPU_2150 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326046.1 244537 R 272635 CDS NP_326047.1 15828687 911633 245143..248529 1 NC_002771.1 no similarity found; hypothetical protein 248529 911633 MYPU_2160 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326047.1 245143 D 272635 CDS NP_326048.1 15828688 911603 248532..249638 1 NC_002771.1 no similarity found; hypothetical protein 249638 911603 MYPU_2170 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326048.1 248532 D 272635 CDS NP_326049.1 15828689 911719 249791..251536 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P15362 (P69_MYCHR) Blastp2 P=1e-94 C=53%; P69-like ABC transporter permease 251536 911719 MYPU_2180 Mycoplasma pulmonis UAB CTIP P69-like ABC transporter permease NP_326049.1 249791 D 272635 CDS NP_326050.1 15828690 911377 complement(251751..252314) 1 NC_002771.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 252314 frr 911377 frr Mycoplasma pulmonis UAB CTIP ribosome recycling factor NP_326050.1 251751 R 272635 CDS NP_326051.1 15828691 910928 complement(252314..253045) 1 NC_002771.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 253045 pyrH 910928 pyrH Mycoplasma pulmonis UAB CTIP uridylate kinase NP_326051.1 252314 R 272635 CDS NP_326052.1 15828692 911561 253360..254883 1 NC_002771.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 254883 glpK 911561 glpK Mycoplasma pulmonis UAB CTIP glycerol kinase NP_326052.1 253360 D 272635 CDS NP_326053.1 15828693 911665 254883..255626 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P52280 (GLPF_MYCGA) Blastp2 P=8e-29 C=47% Pfscan: pos. 5-238 PF00230 | MIP Major intrinsic protein (PDOC00193) pos. 65-73 PS00221 | MIP MIP family signature; glycerol uptake facilitator protein 255626 911665 MYPU_2220 Mycoplasma pulmonis UAB CTIP glycerol uptake facilitator protein NP_326053.1 254883 D 272635 CDS NP_326054.1 15828694 911487 255963..257762 1 NC_002771.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 257762 dnaK 911487 dnaK Mycoplasma pulmonis UAB CTIP molecular chaperone DnaK NP_326054.1 255963 D 272635 CDS NP_326055.1 15828695 910936 complement(257911..258651) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P15361 (P29_MYCHR) Blastp2 P=2e-32 C=52% Pfscan: .pos. 31-49 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 148-220 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 29-224 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 127-179 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 36-43 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 148-162 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 258651 910936 MYPU_2240 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_326055.1 257911 R 272635 CDS NP_326056.1 15828696 911571 complement(258657..259895) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P15363 (P37_MYCHR) Blastp2 P=5e-75 C=56% Pfscan: pos. 14-24 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein ABC transporter substrate -binding protein 259895 911571 MYPU_2250 Mycoplasma pulmonis UAB CTIP lipoprotein ABC transporter substrate -binding protein NP_326056.1 258657 R 272635 CDS NP_326057.1 15828697 911677 260649..261512 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47349 (Y103_MYCGE) Blastp2 P=2e-11 C=38%; hypothetical protein 261512 911677 MYPU_2260 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326057.1 260649 D 272635 CDS NP_326058.1 15828698 911422 261545..262282 1 NC_002771.1 no similarity found Pfscan: pos. 58-238 PF00902 | UPF0032 MttB family (PDOC00936) pos. 41-242 PF01027 | UPF0005 Uncharacterized protein family (PDOC00957); hypothetical protein 262282 911422 MYPU_2270 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326058.1 261545 D 272635 CDS NP_326059.1 15828699 262416..263279 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q44406 (XYLR_ANATH) Blastp2 P=8e-16 C=42%; glucokinase 263279 911422 NP_326059.1 Mycoplasma pulmonis UAB CTIP glucokinase NP_326059.1 262416 D 272635 CDS NP_326060.1 15828700 911531 263593..265116 1 NC_002771.1 no similarity found; hypothetical protein 265116 911531 MYPU_2290 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326060.1 263593 D 272635 CDS NP_326061.1 15828701 911533 265140..266078 1 NC_002771.1 no similarity found; hypothetical protein 266078 911533 MYPU_2300 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326061.1 265140 D 272635 CDS NP_326062.1 15828702 911691 266130..267278 1 NC_002771.1 no similarity found; hypothetical protein 267278 911691 MYPU_2310 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326062.1 266130 D 272635 CDS NP_326063.1 15828703 911373 267278..267835 1 NC_002771.1 no similarity found; hypothetical protein 267835 911373 MYPU_2320 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326063.1 267278 D 272635 CDS NP_326064.1 15828704 910946 267848..270238 1 NC_002771.1 no similarity found; hypothetical protein 270238 910946 MYPU_2330 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326064.1 267848 D 272635 CDS NP_326065.1 15828705 911358 270406..271170 1 NC_002771.1 no similarity found; hypothetical protein 271170 911358 MYPU_2340 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326065.1 270406 D 272635 CDS NP_326066.1 15828706 911537 271185..272774 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P33252 (ATPA_MYCGA) Blastp2 P=2e-89 C=50%; ATP synthase subunit alpha 272774 911537 MYPU_2350 Mycoplasma pulmonis UAB CTIP ATP synthase subunit alpha NP_326066.1 271185 D 272635 CDS NP_326067.2 161723294 911536 273322..274857 1 NC_002771.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 274857 911536 MYPU_2360 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit beta NP_326067.2 273322 D 272635 CDS NP_326068.1 15828708 911518 274992..275948 1 NC_002771.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 275948 eutD 911518 eutD Mycoplasma pulmonis UAB CTIP phosphotransacetylase NP_326068.1 274992 D 272635 CDS NP_326069.1 15828709 911384 275949..277130 1 NC_002771.1 Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; acetate kinase 277130 911384 MYPU_2380 Mycoplasma pulmonis UAB CTIP acetate kinase NP_326069.1 275949 D 272635 CDS NP_326070.1 15828710 911476 277132..277692 1 NC_002771.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 277692 engB 911476 engB Mycoplasma pulmonis UAB CTIP ribosome biogenesis GTP-binding protein YsxC NP_326070.1 277132 D 272635 CDS NP_326071.1 15828711 911519 277974..279401 1 NC_002771.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 279401 911519 MYPU_2400 Mycoplasma pulmonis UAB CTIP pyruvate kinase NP_326071.1 277974 D 272635 CDS NP_326072.1 15828712 911606 complement(279451..280335) 1 NC_002771.1 no similarity found; hypothetical protein 280335 911606 MYPU_2410 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326072.1 279451 R 272635 CDS NP_326073.1 15828713 911541 complement(280402..281136) 1 NC_002771.1 no similarity found; hypothetical protein 281136 911541 MYPU_2420 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326073.1 280402 R 272635 CDS NP_326074.1 15828714 911538 281254..282858 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P46906 (SYR_BACSU) Blastp2 P=3e-97 C=52%; arginyl-tRNA synthetase 282858 911538 MYPU_2430 Mycoplasma pulmonis UAB CTIP arginyl-tRNA synthetase NP_326074.1 281254 D 272635 CDS NP_326075.1 15828715 911441 complement(282939..283751) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47507 (Y265_MYCGE) Blastp2 P=4e-15 C=46% Pfscan: pos. 8-252 PF00592 | DUF3 Domain of Unknown Function 3 pos. 213-235 PS01229 | COF_2 Hypothetical cof family signature 2; hypothetical protein 283751 911441 MYPU_2440 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326075.1 282939 R 272635 CDS NP_326076.1 15828716 911521 284185..286941 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O97291 (O97291) Blastp2 P=4e-06 C=28% Pfscan: pos. 12-22 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 286941 911521 MYPU_2450 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326076.1 284185 D 272635 CDS NP_326077.1 15828717 911410 complement(287574..289889) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O32756 (PGK_LACDE) Blastp2 P=0 C=35%; phosphoglycerate kinase 289889 911410 MYPU_2460 Mycoplasma pulmonis UAB CTIP phosphoglycerate kinase NP_326077.1 287574 R 272635 CDS NP_326078.1 15828718 911517 complement(290030..291865) 1 NC_002771.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 291865 911517 MYPU_2470 Mycoplasma pulmonis UAB CTIP GTP-binding protein LepA NP_326078.1 290030 R 272635 CDS NP_326079.1 15828719 911408 291943..292095 1 NC_002771.1 no similarity found; hypothetical protein 292095 911408 MYPU_2480 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326079.1 291943 D 272635 CDS NP_326080.1 15828720 911451 292113..292277 1 NC_002771.1 no similarity found; hypothetical protein 292277 911451 MYPU_2490 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326080.1 292113 D 272635 CDS NP_326081.1 15828721 911470 complement(292280..293650) 1 NC_002771.1 no similarity found; hypothetical protein 293650 911470 MYPU_2500 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326081.1 292280 R 272635 CDS NP_326082.1 15828722 911353 complement(293970..295115) 1 NC_002771.1 no similarity found; hypothetical protein 295115 911353 MYPU_2510 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326082.1 293970 R 272635 CDS NP_326083.1 15828723 911449 295763..296782 1 NC_002771.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 296782 recA 911449 recA Mycoplasma pulmonis UAB CTIP recombinase A NP_326083.1 295763 D 272635 CDS NP_326084.1 15828724 911488 296872..298707 1 NC_002771.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 298707 911488 MYPU_2530 Mycoplasma pulmonis UAB CTIP tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NP_326084.1 296872 D 272635 CDS NP_326085.1 15828725 911485 298676..299134 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q9ZH20 (Q9ZH20) Blastp2 P=2e-18 C=60%; hypothetical protein 299134 911485 MYPU_2540 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326085.1 298676 D 272635 CDS NP_326086.1 15828726 911480 299173..300147 1 NC_002771.1 in some Mycoplasma, this protein is fused to aspartyl/glutamyl-tRNA amidotransferase subunit C domain; hypothetical protein 300147 911480 MYPU_2550 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326086.1 299173 D 272635 CDS NP_326087.1 15828727 911461 300170..302533 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P09975 (YCF2_MARPO) Blastp2 P=5e-13 C=35%; similar to SWISS-PROT:P47326 (OPPF_MYCGE) P=4e-6 C=17%; hypothetical protein 302533 911461 MYPU_2560 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326087.1 300170 D 272635 CDS NP_326088.1 15828728 911453 302600..305083 1 NC_002771.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 305083 valS 911453 valS Mycoplasma pulmonis UAB CTIP valyl-tRNA synthetase NP_326088.1 302600 D 272635 CDS NP_326089.1 15828729 911486 305061..305879 1 NC_002771.1 METHYLENETETRAHYDROFOLATE DEHYDROGENASE/METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE; identified by sequence similarity; possible; similar to SWISS-PROT:P96050 (FOLD_STRTR) Blastp2 P=8e-38 C=54%; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 305879 911486 MYPU_2580 Mycoplasma pulmonis UAB CTIP methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase NP_326089.1 305061 D 272635 CDS NP_326090.1 15828730 911465 305953..306663 1 NC_002771.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 306663 infC 911465 infC Mycoplasma pulmonis UAB CTIP translation initiation factor IF-3 NP_326090.1 305953 D 272635 CDS NP_326091.1 15828731 911658 306644..306838 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:Q05428 (RL35_MYCFE) Blastp2 P=9e-14 C=63%; 50S ribosomal protein L35 306838 rpmI 911658 rpmI Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L35 NP_326091.1 306644 D 272635 CDS NP_326092.1 15828732 911481 306855..307205 1 NC_002771.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 307205 rplT 911481 rplT Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L20 NP_326092.1 306855 D 272635 CDS NP_326093.1 15828733 911403 307649..309052 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75366 (Y294_MYCPN) Blastp2 P=0 C=63% Pfscan: pos. 17-452 PF00083 | SUGAR_TR Sugar (and other) transporter (PDOC00190) pos. 188-466 PF01236 | NA_GALACTO_SYMP Sodium:galactoside symporter family (PDOC00680); hypothetical protein 309052 911403 MYPU_2620 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326093.1 307649 D 272635 CDS NP_326094.1 15828734 911555 309045..309767 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P37965 (GLPQ_BACSU) Blastp2 P=5e-16 C=35%; glycerophosphoryl diester phosphodiesterase 309767 911555 MYPU_2630 Mycoplasma pulmonis UAB CTIP glycerophosphoryl diester phosphodiesterase NP_326094.1 309045 D 272635 CDS NP_326095.1 15828735 911494 309869..311023 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75063 (Y039_MYCPN) Blastp2 P=4e-85 C=58%; glycerol-3-phosphate dehydrogenase 311023 911494 MYPU_2640 Mycoplasma pulmonis UAB CTIP glycerol-3-phosphate dehydrogenase NP_326095.1 309869 D 272635 CDS NP_326096.1 15828736 911499 complement(311172..311597) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P07678 (ATPE_BACP3) Blastp2 P=2e-14 C=48%; ATP synthase subunit epsilon 311597 911499 MYPU_2650 Mycoplasma pulmonis UAB CTIP ATP synthase subunit epsilon NP_326096.1 311172 R 272635 CDS NP_326097.1 15828737 911682 complement(311566..312993) 1 NC_002771.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 312993 911682 MYPU_2660 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit beta NP_326097.1 311566 R 272635 CDS NP_326098.1 15828738 911357 complement(313005..313844) 1 NC_002771.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 313844 911357 MYPU_2670 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit gamma NP_326098.1 313005 R 272635 CDS NP_326099.1 15828739 911478 complement(313844..315430) 1 NC_002771.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 315430 911478 MYPU_2680 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit alpha NP_326099.1 313844 R 272635 CDS NP_326100.1 15828740 911354 complement(315433..315972) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P17675 (ATPD_BACME) Blastp2 P=9e-12 C=48%; ATP synthase subunit delta 315972 911354 MYPU_2690 Mycoplasma pulmonis UAB CTIP ATP synthase subunit delta NP_326100.1 315433 R 272635 CDS NP_326101.1 15828741 911472 complement(315985..316527) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9X1U9 (Q9X1U9) Blastp2 P=1e-09 C=35%; ATP synthase subunit B 316527 911472 MYPU_2700 Mycoplasma pulmonis UAB CTIP ATP synthase subunit B NP_326101.1 315985 R 272635 CDS NP_326102.1 15828742 911500 complement(316527..316805) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q59550 (ATPL_MYCPN) Blastp2 P=9e-12 C=44%; ATP synthase subunit C 316805 911500 MYPU_2710 Mycoplasma pulmonis UAB CTIP ATP synthase subunit C NP_326102.1 316527 R 272635 CDS NP_326103.1 15828743 911711 complement(316856..317668) 1 NC_002771.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 317668 911711 MYPU_2720 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit A NP_326103.1 316856 R 272635 CDS NP_326104.1 15828744 911466 complement(317652..318131) 1 NC_002771.1 no similarity found; hypothetical protein 318131 911466 MYPU_2730 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326104.1 317652 R 272635 CDS NP_326105.1 15828745 911416 complement(318239..319099) 1 NC_002771.1 no similarity found; hypothetical protein 319099 911416 MYPU_2740 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326105.1 318239 R 272635 CDS NP_326106.1 15828746 911712 319304..319591 1 NC_002771.1 no similarity found; hypothetical protein 319591 911712 MYPU_2750 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326106.1 319304 D 272635 CDS NP_326107.1 15828747 911284 complement(319665..320027) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:O51391 Blastp2 P=4e-18 score=90.5; proline dipeptidase PepQ 320027 911284 MYPU_2760 Mycoplasma pulmonis UAB CTIP proline dipeptidase PepQ NP_326107.1 319665 R 272635 CDS NP_326108.1 15828748 911545 complement(320041..321228) 1 NC_002771.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 321228 911545 MYPU_2770 Mycoplasma pulmonis UAB CTIP phosphopentomutase NP_326108.1 320041 R 272635 CDS NP_326109.1 15828749 complement(321239..321703) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P32321 (DCTD_HUMAN) Blastp2 P=5e-38 C=66%; deoxycytidylate deaminase 321703 911545 NP_326109.1 Mycoplasma pulmonis UAB CTIP deoxycytidylate deaminase NP_326109.1 321239 R 272635 CDS NP_326110.1 15828750 911552 322108..325407 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q21022 (Q21022) Blastp2 P=1e-05 C=7%; hypothetical protein 325407 911552 MYPU_2790 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326110.1 322108 D 272635 CDS NP_326111.1 15828751 911504 complement(325501..325914) 1 NC_002771.1 no similarity found; hypothetical protein 325914 911504 MYPU_2800 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326111.1 325501 R 272635 CDS NP_326112.1 15828752 911673 complement(325932..327440) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q57772 (Y326_METJA) Blastp2 P=2e-45 C=39% Pfscan: pos. 20-441 PF00860 | XAN_UR_PERMEASE Xanthine/uracil permeases family (PDOC00860) pos. 153-453 PF00916 | SULFATE_TRANSP Sulfate transporter family (PDOC00870); hypothetical protein 327440 911673 MYPU_2810 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326112.1 325932 R 272635 CDS NP_326113.1 15828753 911717 327933..330563 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q49551 (Q49551) Blastp2 P=1e-48 C=37% Pfscan: pos. 18-28 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 330563 911717 MYPU_2820 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326113.1 327933 D 272635 CDS NP_326114.1 15828754 911359 330563..331621 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47323 (OPPB_MYCGE) Blastp2 P=3e-39 C=50% Pfscan: pos. 210-281 PF00528 | BPD_TRANSP Binding-protein-dependent transport systems inner membrane component; oligopeptide ABC transporter permease 331621 911359 MYPU_2830 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter permease NP_326114.1 330563 D 272635 CDS NP_326115.1 15828755 911553 331608..332762 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47324 (OPPC_MYCGE) Blastp2 P=9e-32 C=42%; oligopeptide ABC transporter permease 332762 911553 MYPU_2840 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter permease NP_326115.1 331608 D 272635 CDS NP_326116.1 15828756 911462 332764..333867 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P47325 (OPPD_MYCGE) Blastp2 P=2e-95 C=66% Pfscan: pos. 179-251 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 57-255 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 156-210 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 64-71 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 179-193 PS00211 | ABC_TRANSPORTER ABC transporters family signature; oligopeptide ABC transporter ATP-binding protein 333867 911462 MYPU_2850 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter ATP-binding protein NP_326116.1 332764 D 272635 CDS NP_326117.1 15828757 911557 333860..336205 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47326 (OPPF_MYCGE) Blastp2 P=1e-79 C=51% Pfscan: pos. 40-63 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 624-696 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 38-700 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 602-655 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 45-52 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 624-638 PS00211 | ABC_TRANSPORTER ABC transporters family signature; oligopeptide ABC transporter ATP-binding protein 336205 911557 MYPU_2860 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter ATP-binding protein NP_326117.1 333860 D 272635 CDS NP_326118.1 15828758 911345 complement(336289..336780) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:P75288 (P75288) Blastp2 P=1e-08 C=42% Pfscan: pos. 136-143 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 336780 911345 MYPU_2870 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326118.1 336289 R 272635 CDS NP_326119.1 15828759 911400 complement(336789..339146) 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q49097 (Q49097) Blastp2 P=4e-13 C=15% Pfscan: pos. 24-34 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 339146 911400 MYPU_2880 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326119.1 336789 R 272635 CDS NP_326120.1 15828760 910915 complement(339291..339659) 1 NC_002771.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 339659 rplL 910915 rplL Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L7/L12 NP_326120.1 339291 R 272635 CDS NP_326121.1 15828761 911678 complement(339705..340265) 1 NC_002771.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 340265 rplJ 911678 rplJ Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L10 NP_326121.1 339705 R 272635 CDS NP_326122.1 15828762 911413 complement(340358..340915) 1 NC_002771.1 no similarity found Pfscan: pos. 15-25 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 340915 911413 MYPU_2910 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326122.1 340358 R 272635 CDS NP_326123.1 15828763 911406 complement(340928..341920) 1 NC_002771.1 no similarity found; hypothetical protein 341920 911406 MYPU_2920 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326123.1 340928 R 272635 CDS NP_326124.1 15828764 911444 complement(342021..343580) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O51530 (O51530) Blastp2 P=4e-15 C=19%; hypothetical protein 343580 911444 MYPU_2930 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326124.1 342021 R 272635 CDS NP_326125.1 15828765 911292 343672..343827 1 NC_002771.1 no similarity found; hypothetical protein 343827 911292 MYPU_2940 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326125.1 343672 D 272635 CDS NP_326126.1 15828766 911657 complement(344034..344708) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75428 (Y247_MYCPN) Blastp2 P=9e-19 C=44%; hypothetical protein 344708 911657 MYPU_2950 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326126.1 344034 R 272635 CDS NP_326127.1 15828767 911335 complement(344746..345675) 1 NC_002771.1 no similarity found; hypothetical protein 345675 911335 MYPU_2960 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326127.1 344746 R 272635 CDS NP_326128.1 15828768 911527 complement(345726..347291) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:O06005 (AAPA_BACSU) Blastp2 P=2e-8 C=32% Pfscan: pos. 4-399 PS50285 | AMINO_ACID_PERMEASE_2 Permeases for amino acids and related compounds, family I pos. 15-443 PF00324 | AA_PERMEASES Amino acid permease (PDOC00191); amino acid permease 347291 911527 MYPU_2970 Mycoplasma pulmonis UAB CTIP amino acid permease NP_326128.1 345726 R 272635 CDS NP_326129.1 15828769 911407 complement(347371..348261) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:Q45480 (YLYB_BACSU) Blastp2 P=2e-69 C=62% Pfscan: pos. 78-245 PF00849 | YABO Hypothetical yabO/yceC/sfhB family (PDOC00869) (PDOC00885) pos. 129-143 PS01129 | PSI_RLU Rlu family of pseudouridine synthase signature; pseudouridylate synthase 348261 911407 MYPU_2980 Mycoplasma pulmonis UAB CTIP pseudouridylate synthase NP_326129.1 347371 R 272635 CDS NP_326130.1 15828770 911409 348466..349389 1 NC_002771.1 no similarity found; hypothetical protein 349389 911409 MYPU_2990 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326130.1 348466 D 272635 CDS NP_326131.1 15828771 910917 complement(349429..350160) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:O07874 (RNH2_STRPN) Blastp2 P=3e-15 C=40% Pfscan: pos. 22-226 PF01351 | RNASE_HII Ribonuclease HII; ribonuclease HII (RNase HII) 350160 910917 MYPU_3000 Mycoplasma pulmonis UAB CTIP ribonuclease HII (RNase HII) NP_326131.1 349429 R 272635 CDS NP_326132.1 15828772 911329 complement(350150..351073) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P43051 (YUPP_MYCHO) Blastp2 P=3e-89 C=67% Pfscan: pos. 11-269 PF00592 | DUF3 Domain of Unknown Function 3 pos. 11-22 PS01228 | COF_1 Hypothetical cof family signature 1; hypothetical protein 351073 911329 MYPU_3010 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326132.1 350150 R 272635 CDS NP_326133.1 15828773 911442 complement(351140..351628) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P94559 (YSNB_BACSU) Blastp2 P=1e-13 C=47% Pfscan: pos. 3-158 PF01143 | UPF0025 Uncharacterized protein family UPF0025 (PDOC00976); hypothetical protein 351628 911442 MYPU_3020 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326133.1 351140 R 272635 CDS NP_326134.1 15828774 911492 351702..352226 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P32813 (YGL3_BACST) Blastp2 P=2e-35 C=61%; tRNA/rRNA methyltransferase 352226 911492 MYPU_3030 Mycoplasma pulmonis UAB CTIP tRNA/rRNA methyltransferase NP_326134.1 351702 D 272635 CDS NP_326135.1 15828775 911419 352219..352971 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P74261 (YG73_SYNY3) Blastp2 P=2e-14 C=46%; tRNA/rRNA methyltransferase 352971 911419 MYPU_3040 Mycoplasma pulmonis UAB CTIP tRNA/rRNA methyltransferase NP_326135.1 352219 D 272635 CDS NP_326136.1 15828776 911608 352940..353233 1 NC_002771.1 no similarity found; hypothetical protein 353233 911608 MYPU_3050 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326136.1 352940 D 272635 CDS NP_326137.1 15828777 911613 353211..354086 1 NC_002771.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 354086 rbgA 911613 rbgA Mycoplasma pulmonis UAB CTIP ribosomal biogenesis GTPase NP_326137.1 353211 D 272635 CDS NP_326138.1 15828778 911448 354076..354945 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O67810 (O67810) Blastp2 P=1e-10 C=41%; hypothetical protein 354945 911448 MYPU_3070 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326138.1 354076 D 272635 CDS NP_326139.1 15828779 911506 355056..358109 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q50279 Blastp2 P=2e-04 score=48; hypothetical protein 358109 911506 MYPU_3080 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326139.1 355056 D 272635 CDS NP_326140.1 15828780 911362 complement(358106..359002) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:O34513 (O34513) Blastp2 P=5e-41 C=58%; hypothetical protein 359002 911362 MYPU_3090 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326140.1 358106 R 272635 CDS NP_326141.1 15828781 911632 359109..359945 1 NC_002771.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 359945 911632 MYPU_3100 Mycoplasma pulmonis UAB CTIP formamidopyrimidine-DNA glycosylase NP_326141.1 359109 D 272635 CDS NP_326142.1 15828782 911641 359983..360348 1 NC_002771.1 no similarity found; hypothetical protein 360348 911641 MYPU_3110 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326142.1 359983 D 272635 CDS NP_326143.1 15828783 911530 360427..361023 1 NC_002771.1 catalyzes the hydrolytic cleavage of the 4'-phosphopantetheine residue from ACP; azoreductase 361023 acpD 911530 acpD Mycoplasma pulmonis UAB CTIP azoreductase NP_326143.1 360427 D 272635 CDS NP_326144.1 15828784 911266 361181..369640 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O30704 Blastp2 P=3e-19 score=99 Pfscan: pos. 121-240 PS50241 | LIPASE_GDSL Lipase/Acylhydrolase with GDSL-like motif. pos. 121-240 PF00657 | LIPASE_GDSL Lipase/Acylhydrolase with GDSL-like motif (PDOC00842); hypothetical protein 369640 911266 MYPU_3130 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326144.1 361181 D 272635 CDS NP_326145.1 15828785 911351 369845..370534 1 NC_002771.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 370534 911351 MYPU_3140 Mycoplasma pulmonis UAB CTIP deoxyribose-phosphate aldolase NP_326145.1 369845 D 272635 CDS NP_326146.1 15828786 911455 370535..371161 1 NC_002771.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 371161 upp 911455 upp Mycoplasma pulmonis UAB CTIP uracil phosphoribosyltransferase NP_326146.1 370535 D 272635 CDS NP_326147.1 15828787 911696 complement(371276..373171) 1 NC_002771.1 no similarity found Pfscan: pos. 16-26 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 373171 911696 MYPU_3160 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326147.1 371276 R 272635 CDS NP_326148.1 15828788 911562 complement(373143..373298) 1 NC_002771.1 no similarity found; hypothetical protein 373298 911562 MYPU_3170 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326148.1 373143 R 272635 CDS NP_326149.1 15828789 911507 complement(373349..375256) 1 NC_002771.1 no similarity found Pfscan: pos. 16-26 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 375256 911507 MYPU_3180 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326149.1 373349 R 272635 CDS NP_326150.1 15828790 911385 complement(375574..377502) 1 NC_002771.1 no similarity found Pfscan: pos. 16-26 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 377502 911385 MYPU_3190 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326150.1 375574 R 272635 CDS NP_326151.1 15828791 911473 complement(377687..379540) 1 NC_002771.1 no similarity found Pfscan: pos. 15-25 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 379540 911473 MYPU_3200 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326151.1 377687 R 272635 CDS NP_326152.1 15828792 910950 complement(379654..381495) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O31605 (PEPF_BACSU) Blastp2 P=5e-73 C=42% Pfscan: pos. 392-401 PS00142 | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature; oligoendopeptidase F 381495 910950 MYPU_3210 Mycoplasma pulmonis UAB CTIP oligoendopeptidase F NP_326152.1 379654 R 272635 CDS NP_326153.1 15828793 911692 complement(381498..382010) 1 NC_002771.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 382010 911692 MYPU_3220 Mycoplasma pulmonis UAB CTIP adenine phosphoribosyltransferase NP_326153.1 381498 R 272635 CDS NP_326154.1 15828794 911501 complement(382038..383933) 1 NC_002771.1 no similarity found Pfscan: pos. 14-24 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 383933 911501 MYPU_3230 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326154.1 382038 R 272635 CDS NP_326155.1 15828795 911542 384281..384466 1 NC_002771.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 384466 rpmF 911542 rpmF Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L32 NP_326155.1 384281 D 272635 CDS NP_326156.1 15828796 911620 384541..385287 1 NC_002771.1 no similarity found; hypothetical protein 385287 911620 MYPU_3250 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326156.1 384541 D 272635 CDS NP_326157.1 15828797 911634 385403..385936 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O28566 (O28566) Blastp2 P=2e-10 C=45%; hypothetical protein 385936 911634 MYPU_3260 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326157.1 385403 D 272635 CDS NP_326158.1 15828798 911471 complement(385956..386357) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P46323 (CINA_BACSU) Blastp2 P=2e-18 C=57%; competence-damage protein 386357 911471 MYPU_3270 Mycoplasma pulmonis UAB CTIP competence-damage protein NP_326158.1 385956 R 272635 CDS NP_326159.1 15828799 911630 complement(386426..386692) 1 NC_002771.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 386692 rpsO 911630 rpsO Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S15 NP_326159.1 386426 R 272635 CDS NP_326160.1 15828800 911326 complement(386762..387019) 1 NC_002771.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 387019 rpmA 911326 rpmA Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L27 NP_326160.1 386762 R 272635 CDS NP_326161.2 161723293 911290 complement(387031..387330) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47474 (RL21_MYCGE) Blastp2 P=2e-21 C=50%; 50S ribosomal protein L21 387330 rplU 911290 rplU Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L21 NP_326161.2 387031 R 272635 CDS NP_326162.1 15828802 911628 complement(387562..387834) 1 NC_002771.1 no similarity found; hypothetical protein 387834 911628 MYPU_3310 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326162.1 387562 R 272635 CDS NP_326163.1 15828803 911616 complement(387912..389648) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:O32038 (SYD_BACSU) Blastp2 P=0 C=59%; aspartyl-tRNA synthetase 389648 911616 MYPU_3320 Mycoplasma pulmonis UAB CTIP aspartyl-tRNA synthetase NP_326163.1 387912 R 272635 CDS NP_326164.1 15828804 911572 complement(389608..390870) 1 NC_002771.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 390870 hisS 911572 hisS Mycoplasma pulmonis UAB CTIP histidyl-tRNA synthetase NP_326164.1 389608 R 272635 CDS NP_326165.1 15828805 911560 complement(390955..391785) 1 NC_002771.1 no similarity found; hypothetical protein 391785 911560 MYPU_3340 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326165.1 390955 R 272635 CDS NP_326166.1 15828806 911687 391893..392993 1 NC_002771.1 catalyzes the reversible adenylation of nicotinate mononucleotide to nicotinic acid adenine dinucleotide; nicotinate-nucleotide adenylyltransferase 392993 nadD 911687 nadD Mycoplasma pulmonis UAB CTIP nicotinate-nucleotide adenylyltransferase NP_326166.1 391893 D 272635 CDS NP_326167.1 15828807 911355 392971..393654 1 NC_002771.1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 393654 911355 MYPU_3360 Mycoplasma pulmonis UAB CTIP 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NP_326167.1 392971 D 272635 CDS NP_326168.1 15828808 911700 393656..394354 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P35159 (RLUB_BACSU) Blastp2 P=2e-33 C=56% Pfscan: pos. 98-112 PS01149 | PSI_RSU Rsu family of pseudouridine synthase signature; pseudouridylate synthase 394354 911700 MYPU_3370 Mycoplasma pulmonis UAB CTIP pseudouridylate synthase NP_326168.1 393656 D 272635 CDS NP_326169.1 15828809 911655 complement(394856..396706) 1 NC_002771.1 no similarity found Pfsan: pos. 15-25 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 396706 911655 MYPU_3380 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326169.1 394856 R 272635 CDS NP_326170.1 15828810 911322 complement(396759..398000) 1 NC_002771.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 398000 glyA 911322 glyA Mycoplasma pulmonis UAB CTIP serine hydroxymethyltransferase NP_326170.1 396759 R 272635 CDS NP_326171.1 15828811 911714 398352..398501 1 NC_002771.1 no similarity found; hypothetical protein 398501 911714 MYPU_3400 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326171.1 398352 D 272635 CDS NP_326172.1 15828812 911534 complement(398572..400281) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P54463 (YQEW_BACSU) Blastp2 P=3e-16 C=22%; hypothetical protein 400281 911534 MYPU_3410 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326172.1 398572 R 272635 CDS NP_326173.1 15828813 911349 400363..401712 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P37105 (SR54_BACSU) Blastp2 P=3e-94 C=59%; signal recognition particle protein 401712 911349 MYPU_3420 Mycoplasma pulmonis UAB CTIP signal recognition particle protein NP_326173.1 400363 D 272635 CDS NP_326174.1 15828814 911636 401976..403358 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P46192 (P46_MYCHY) Blastp2 P=1e-44 C=44%; similar to SWISSPROT:P54082 (CVE2_AGRTU) Blastp2 P=3e-12 C=28% Pfscan: pos. 60-380 PF00532 | PERIPLA_BP_LIKE Periplasmic binding proteins and LacI family pos. 21-31 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 403358 911636 MYPU_3430 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326174.1 401976 D 272635 CDS NP_326175.1 15828815 910914 403445..405025 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P45046 (XYLG_HAEIN) Blastp2 P=0 C=58% Pfscan: pos. 36-58 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 147-219 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 417-488 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 34-223 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 297-492 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 395-448 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 41-48 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 417-431 PS00211 | ABC_TRANSPORTER ABC transporters family signature; xylose ABC transporter ATP-binding protein 405025 910914 MYPU_3440 Mycoplasma pulmonis UAB CTIP xylose ABC transporter ATP-binding protein NP_326175.1 403445 D 272635 CDS NP_326176.1 15828816 911516 404976..406892 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P45045 (XYLH_HAEIN) Blastp2 P=1e-40 C=27% Pfscan: pos. 281-634 PS50281 | BPD_TRANSP_INN_MEMB_2 Binding-system dependent bacterial transporters (araH, livH/lim; xylose ABC transporter permease 406892 911516 MYPU_3450 Mycoplasma pulmonis UAB CTIP xylose ABC transporter permease NP_326176.1 404976 D 272635 CDS NP_326177.1 15828817 911302 complement(407185..408570) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q48902 (Q48902) Blastp2 P=1e-60 C=46% Pfscan: pos. 17-27 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; ABC transporter 408570 911302 MYPU_3460 Mycoplasma pulmonis UAB CTIP ABC transporter NP_326177.1 407185 R 272635 CDS NP_326178.1 15828818 911393 complement(408717..410873) 1 NC_002771.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 410873 pheT 911393 pheT Mycoplasma pulmonis UAB CTIP phenylalanyl-tRNA synthetase subunit beta NP_326178.1 408717 R 272635 CDS NP_326179.1 15828819 911343 complement(410882..411826) 1 NC_002771.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 411826 pheS 911343 pheS Mycoplasma pulmonis UAB CTIP phenylalanyl-tRNA synthetase subunit alpha NP_326179.1 410882 R 272635 CDS NP_326180.1 15828820 911511 complement(411854..412567) 1 NC_002771.1 no similarity found; hypothetical protein 412567 911511 MYPU_3490 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326180.1 411854 R 272635 CDS NP_326181.1 15828821 911716 complement(412741..413013) 1 NC_002771.1 no similarity found; hypothetical protein 413013 911716 MYPU_3500 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326181.1 412741 R 272635 CDS NP_326182.1 15828822 911554 413074..415251 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P21499 (VACB_ECOLI) Blastp2 P=6e-81 C=38%; ribonuclease II 415251 911554 MYPU_3510 Mycoplasma pulmonis UAB CTIP ribonuclease II NP_326182.1 413074 D 272635 CDS NP_326183.1 15828823 911514 415226..415663 1 NC_002771.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 415663 smpB 911514 smpB Mycoplasma pulmonis UAB CTIP SsrA-binding protein NP_326183.1 415226 D 272635 CDS NP_326184.1 15828824 911417 415696..416952 1 NC_002771.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 416952 obgE 911417 obgE Mycoplasma pulmonis UAB CTIP GTPase ObgE NP_326184.1 415696 D 272635 CDS NP_326185.1 15828825 911505 417024..417149 1 NC_002771.1 no similarity found; hypothetical protein 417149 911505 MYPU_3540 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326185.1 417024 D 272635 CDS NP_326186.1 15828826 911379 418035..418388 1 NC_002771.1 no similarity found; hypothetical protein 418388 911379 MYPU_3550 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326186.1 418035 D 272635 CDS NP_326187.1 15828827 911617 418381..419514 1 NC_002771.1 no similarity found; hypothetical protein 419514 911617 MYPU_3560 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326187.1 418381 D 272635 CDS NP_326188.1 15828828 911660 419498..419938 1 NC_002771.1 no similarity found; hypothetical protein 419938 911660 MYPU_3570 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326188.1 419498 D 272635 CDS NP_326189.1 15828829 911647 419958..420179 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:O67611 (ACP_AQUAE) Blastp2 P=3e-07 C=59%; acyl carrier protein 420179 911647 MYPU_3580 Mycoplasma pulmonis UAB CTIP acyl carrier protein NP_326189.1 419958 D 272635 CDS NP_326190.1 15828830 911432 complement(420239..421105) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47568 (Y326_MYCGE) Blastp2 P=4e-14 C=44%; hypothetical protein 421105 911432 MYPU_3590 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326190.1 420239 R 272635 CDS NP_326191.1 15828831 910940 complement(421905..422747) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47269 (ALF_MYCGE) Blastp2 P=4e-31 C=51%; fructose-bisphosphate aldolase 422747 910940 MYPU_3600 Mycoplasma pulmonis UAB CTIP fructose-bisphosphate aldolase NP_326191.1 421905 R 272635 CDS NP_326192.1 15828832 911388 complement(422859..424436) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P45604 (PTAA_KLEPN) Blastp2 P=2e-55 C=42% Pfscan: pos. 484-508 PF00367 | PTS_EIIB phosphotransferase system, EIIB (PDOC00795); PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG)(N-acetylglucosamine-permease IIABC component) (phosphotransferase enzyme II, ABC component) (EII-NAG) 424436 911388 MYPU_3610 Mycoplasma pulmonis UAB CTIP PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG)(N-acetylglucosamine-permease IIABC component) (phosphotransferase enzyme II, ABC component) (EII-NAG) NP_326192.1 422859 R 272635 CDS NP_326193.1 15828833 911565 complement(424440..425210) 1 NC_002771.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 425210 nagB 911565 nagB Mycoplasma pulmonis UAB CTIP glucosamine-6-phosphate deaminase NP_326193.1 424440 R 272635 CDS NP_326194.1 15828834 911397 complement(425220..425906) 1 NC_002771.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 425906 911397 MYPU_3630 Mycoplasma pulmonis UAB CTIP N-acetylmannosamine-6-phosphate 2-epimerase NP_326194.1 425220 R 272635 CDS NP_326195.1 15828835 911713 complement(425913..427721) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P20166 (PTGA_BACSU) Blastp2 P=2e-54 C=39% Pfscan: pos. 529-562 PF00367 | PTS_EIIB phosphotransferase system, EIIB (PDOC00795) pos. 540-557 PS01035 | PTS_EIIB_CYS PTS EIIB domains cysteine phosphorylation site signature; PTS system, glucose-specific IIABC component (EIIABC-glc) (glucose-permease IIABC component) (phosphotransferase enzyme II, ABC component) (EII-glc/EIII-glc) 427721 911713 MYPU_3640 Mycoplasma pulmonis UAB CTIP PTS system, glucose-specific IIABC component (EIIABC-glc) (glucose-permease IIABC component) (phosphotransferase enzyme II, ABC component) (EII-glc/EIII-glc) NP_326195.1 425913 R 272635 CDS NP_326196.1 15828836 911639 428019..428171 1 NC_002771.1 no similarity found; hypothetical protein 428171 911639 MYPU_3650 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326196.1 428019 D 272635 CDS NP_326197.1 15828837 911624 428353..428697 1 NC_002771.1 no similarity found; hypothetical protein 428697 911624 MYPU_3660 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326197.1 428353 D 272635 CDS NP_326198.1 15828838 911611 428764..429174 1 NC_002771.1 no similarity found; hypothetical protein 429174 911611 MYPU_3670 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326198.1 428764 D 272635 CDS NP_326199.1 15828839 911625 429122..429532 1 NC_002771.1 no similarity found; hypothetical protein 429532 911625 MYPU_3680 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326199.1 429122 D 272635 CDS NP_326200.1 15828840 911383 429581..430342 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O34450 (NAGA_BACSU) Blastp2 P=2e-32 C=52%; N-acetylglucosamine-6-phosphate deacetylase 430342 911383 MYPU_3690 Mycoplasma pulmonis UAB CTIP N-acetylglucosamine-6-phosphate deacetylase NP_326200.1 429581 D 272635 CDS NP_326201.1 15828841 911402 431077..431955 1 NC_002771.1 no similarity found; hypothetical protein 431955 911402 MYPU_3700 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326201.1 431077 D 272635 CDS NP_326202.1 15828842 911381 complement(432580..433686) 1 NC_002771.1 no similarity found Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 433686 911381 MYPU_3710 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326202.1 432580 R 272635 CDS NP_326203.1 15828843 911676 433906..435834 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:Q59192 (PARE_BACSU) Blastp2 P=0 C=71%; topoisomerase IV subunit B 435834 911676 MYPU_3720 Mycoplasma pulmonis UAB CTIP topoisomerase IV subunit B NP_326203.1 433906 D 272635 CDS NP_326204.1 15828844 911708 435827..438646 1 NC_002771.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 438646 911708 MYPU_3730 Mycoplasma pulmonis UAB CTIP DNA topoisomerase IV subunit A NP_326204.1 435827 D 272635 CDS NP_326205.1 15828845 911360 438649..440097 1 NC_002771.1 no similarity found; Pfscan: pos. 17-27 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 440097 911360 MYPU_3740 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326205.1 438649 D 272635 CDS NP_326206.1 15828846 910941 440169..441548 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47707 (AMPL_MYCSA) Blastp2 P=1e-90 C=55% Pfscan: pos. 40-432 PF00883 | PEPTIDASE_M17 Cytosol aminopeptidase (PDOC00548); aminopeptidase 441548 910941 MYPU_3750 Mycoplasma pulmonis UAB CTIP aminopeptidase NP_326206.1 440169 D 272635 CDS NP_326207.1 15828847 911702 441686..443728 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q49430 (Y390_MYCGE) Blastp2 P=7e-29 C=40% Pfscan: pos. 497-522 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 605-675 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 495-677 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 157-427 PF00664 | ABC_MEMBRANE ABC transporter transmembrane region. pos. 584-636 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 502-509 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) TMpred prediction: 5 transmembrane helices; ABC transporter permease/ATP-binding protein 443728 911702 MYPU_3760 Mycoplasma pulmonis UAB CTIP ABC transporter permease/ATP-binding protein NP_326207.1 441686 D 272635 CDS NP_326208.1 15828848 911390 443706..444092 1 NC_002771.1 no similarity found; hypothetical protein 444092 911390 MYPU_3770 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326208.1 443706 D 272635 CDS NP_326209.1 15828849 911389 444130..444579 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O67367 (YD54_AQUAE) Blastp2 P=1e-15 C=42% Pfscan: pos. 115-125 PS01306 | UPF0054 Uncharacterized protein family UPF0054 signature; hypothetical protein 444579 911389 MYPU_3780 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326209.1 444130 D 272635 CDS NP_326210.1 15828850 911398 444619..444957 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P19079 (CDD_BACSU) Blastp2 P=1e-17 C=59%; cytidine deaminase 444957 911398 MYPU_3790 Mycoplasma pulmonis UAB CTIP cytidine deaminase NP_326210.1 444619 D 272635 CDS NP_326211.1 15828851 911387 445030..445911 1 NC_002771.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 445911 era 911387 era Mycoplasma pulmonis UAB CTIP GTP-binding protein Era NP_326211.1 445030 D 272635 CDS NP_326212.1 15828852 911723 complement(446020..446430) 1 NC_002771.1 no similarity found; hypothetical protein 446430 911723 MYPU_3810 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326212.1 446020 R 272635 CDS NP_326213.1 15828853 911394 complement(446443..449994) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9YVT6 (Q9YVT6) Blastp2 P=3e-09 C=32%; hypothetical protein 449994 911394 MYPU_3820 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326213.1 446443 R 272635 CDS NP_326214.1 15828854 911346 complement(449966..452527) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q07725 (Q07725) Blastp2 P=1e-27 C=28% Pfscan: pos. 505-512 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); TRSE-like protein 452527 911346 MYPU_3830 Mycoplasma pulmonis UAB CTIP TRSE-like protein NP_326214.1 449966 R 272635 CDS NP_326215.1 15828855 911414 complement(452527..453639) 1 NC_002771.1 no similarity found; hypothetical protein 453639 911414 MYPU_3840 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326215.1 452527 R 272635 CDS NP_326216.1 15828856 911344 complement(453620..453937) 1 NC_002771.1 no similarity found; hypothetical protein 453937 911344 MYPU_3850 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326216.1 453620 R 272635 CDS NP_326217.1 15828857 911392 454104..454901 1 NC_002771.1 with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 454901 cbiO 911392 cbiO Mycoplasma pulmonis UAB CTIP cobalt transporter ATP-binding subunit NP_326217.1 454104 D 272635 CDS NP_326218.1 15828858 911332 454892..455806 1 NC_002771.1 with CbiNQ forms the ABC transporter for cobalt import; Mycoplasmas have two adjacent copies of this gene; cobalt transporter ATP-binding subunit 455806 911332 MYPU_3870 Mycoplasma pulmonis UAB CTIP cobalt transporter ATP-binding subunit NP_326218.1 454892 D 272635 CDS NP_326219.1 15828859 911350 455838..456728 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q50292 (Y181_MYCPN) Blastp2 P=3e-19 C=21% TMpred: 5 transmembrane helices; ABC transporter permease 456728 911350 MYPU_3880 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_326219.1 455838 D 272635 CDS NP_326220.1 15828860 911331 456736..458775 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P78021 (DNLJ_MYCPN) Blastp2 P=3e-86 C=48%; DNA ligase (polydeoxyribonucleotide synthase [NAD+]) 458775 911331 MYPU_3890 Mycoplasma pulmonis UAB CTIP DNA ligase (polydeoxyribonucleotide synthase [NAD+]) NP_326220.1 456736 D 272635 CDS NP_326221.1 15828861 910934 458768..460300 1 NC_002771.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 460300 lysS 910934 lysS Mycoplasma pulmonis UAB CTIP lysyl-tRNA synthetase NP_326221.1 458768 D 272635 CDS NP_326222.1 15828862 910930 complement(460638..461078) 1 NC_002771.1 identified by sequence similarity; possible; similar to GenBank: Z16416 ; Bhugra,B. and Dybvig,K. ; Identification and characterization of IS1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); truncated IS1138 transposase 461078 910930 MYPU_3910 Mycoplasma pulmonis UAB CTIP truncated IS1138 transposase NP_326222.1 460638 R 272635 CDS NP_326223.1 15828863 911378 complement(461088..461648) 1 NC_002771.1 identified by sequence similarity; similar to GenBank: Z16416; Bhugra,B. and Dybvig,K. ; Identification and characterization of IS1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); truncated IS1138 transposase 461648 911378 MYPU_3920 Mycoplasma pulmonis UAB CTIP truncated IS1138 transposase NP_326223.1 461088 R 272635 CDS NP_326224.1 15828864 911305 complement(461761..464034) 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q49096 (Q49096) Blastp2 P=9e-15 C=8% Pfscan: pos. 48-129 PS50099 | PRO_RICH Proline-rich region.; hypothetical protein 464034 911305 MYPU_3930 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326224.1 461761 R 272635 CDS NP_326225.1 15828865 911695 464060..465268 1 NC_002771.1 identified by sequence similarity; identical to GENBANK:Z16416 pos. 54-1259 ; Bhugra,B. and Dybvig,K. ; Identification and characterization of IS1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); IS1138 transposase 465268 911695 MYPU_3940 Mycoplasma pulmonis UAB CTIP IS1138 transposase NP_326225.1 464060 D 272635 CDS NP_326226.1 15828866 911497 complement(465695..468388) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9ZJK9 Blastp2 P=2e-79 score=294; type III restriction-modification system: methylase 468388 911497 MYPU_3950 Mycoplasma pulmonis UAB CTIP type III restriction-modification system: methylase NP_326226.1 465695 R 272635 CDS NP_326227.1 15828867 911382 complement(468565..470286) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P08763 (T3MO_BPP1) Blastp2 P=6e-37 C=32%; type III restriction-modification system: methylase 470286 911382 MYPU_3960 Mycoplasma pulmonis UAB CTIP type III restriction-modification system: methylase NP_326227.1 468565 R 272635 CDS NP_326228.1 15828868 911423 complement(470561..472258) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P08763 (T3MO_BPP1) Blastp2 P=2e-34 C=30%; type III restriction-modification system: methylase 472258 911423 MYPU_3970 Mycoplasma pulmonis UAB CTIP type III restriction-modification system: methylase NP_326228.1 470561 R 272635 CDS NP_326229.1 15828869 911548 complement(472298..474256) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P12364 (T3MO_ECOLI) Blastp2 P=5e-22 C=27%; type III restriction-modification system: methylase 474256 911548 MYPU_3980 Mycoplasma pulmonis UAB CTIP type III restriction-modification system: methylase NP_326229.1 472298 R 272635 CDS NP_326230.1 15828870 911391 complement(474683..475123) 1 NC_002771.1 identified by sequence similarity; possible; similar to GenBank: Z16416 ; Bhugra,B. and Dybvig,K. ; Identification and characterization of IS1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); truncated IS1138 transposase 475123 911391 MYPU_3990 Mycoplasma pulmonis UAB CTIP truncated IS1138 transposase NP_326230.1 474683 R 272635 CDS NP_326231.1 15828871 911318 complement(475133..475693) 1 NC_002771.1 identified by sequence similarity; possible; similar to GenBank: Z16416 ; Bhugra,B. and Dybvig,K. ; Identification and characterization of IS1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); truncated IS1138 transposase 475693 911318 MYPU_4000 Mycoplasma pulmonis UAB CTIP truncated IS1138 transposase NP_326231.1 475133 R 272635 CDS NP_326232.1 15828872 911510 475986..477089 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P78021 (DNLJ_MYCPN) Blastp2 P=2e-48 C=52%; DNA ligase (polydeoxyribonucleotide synthase [NAD+]) (fragment) 477089 911510 MYPU_4010 Mycoplasma pulmonis UAB CTIP DNA ligase (polydeoxyribonucleotide synthase [NAD+]) (fragment) NP_326232.1 475986 D 272635 CDS NP_326233.1 15828873 910931 477186..478661 1 NC_002771.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 478661 lysS 910931 lysS Mycoplasma pulmonis UAB CTIP lysyl-tRNA synthetase NP_326233.1 477186 D 272635 CDS NP_326234.1 15828874 911306 complement(479011..479151) 1 NC_002771.1 no similarity found; hypothetical protein 479151 911306 MYPU_4030 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326234.1 479011 R 272635 CDS NP_326235.1 15828875 910932 complement(479338..480123) 1 NC_002771.1 no similarity found; hypothetical protein 480123 910932 MYPU_4040 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326235.1 479338 R 272635 CDS NP_326236.1 15828876 911347 complement(480230..481420) 1 NC_002771.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 481420 tuf 911347 tuf Mycoplasma pulmonis UAB CTIP elongation factor Tu NP_326236.1 480230 R 272635 CDS NP_326237.1 15828877 910935 481771..483108 1 NC_002771.1 no similarity found Pfscan: pos. 214-268 PF00430 | ATP_SYNT_B ATP synthase B/B' CF(0); hypothetical protein 483108 910935 MYPU_4060 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326237.1 481771 D 272635 CDS NP_326238.1 15828878 911281 483223..483849 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47351 (Y105_MYCGE) Blastp2 P=2e-21 C=43%; hypothetical protein 483849 911281 MYPU_4070 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326238.1 483223 D 272635 CDS NP_326239.1 15828879 911424 483851..485308 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:O50166 (O50166) Blastp2 P=3e-58 C=49%; Mg2+ transporter 485308 911424 MYPU_4080 Mycoplasma pulmonis UAB CTIP Mg2+ transporter NP_326239.1 483851 D 272635 CDS NP_326240.1 15828880 911396 485524..485691 1 NC_002771.1 no similarity found; hypothetical protein 485691 911396 MYPU_4090 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326240.1 485524 D 272635 CDS NP_326241.1 15828881 911654 485792..486898 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P24138 (OPPB_BACSU) Blastp2 P=3e-30 C=39%; oligopeptide ABC transporter system permease OPPB 486898 911654 MYPU_4100 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter system permease OPPB NP_326241.1 485792 D 272635 CDS NP_326242.1 15828882 911550 486898..487860 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P18794 (AMID_STRPN) Blastp2 P=7e-31 C=38%; oligopeptide ABC transporter system permease OPPC 487860 911550 MYPU_4110 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter system permease OPPC NP_326242.1 486898 D 272635 CDS NP_326243.1 15828883 911452 487863..489326 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P24136 (OPPD_BACSU) Blastp2 P=1e-77 C=44% Pfscan: pos. 292-364 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 168-368 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 273-323 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 175-182 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 292-306 PS00211 | ABC_TRANSPORTER ABC transporters family signature; oligopeptide ABC transporter ATP-binding protein OppD 489326 911452 MYPU_4120 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter ATP-binding protein OppD NP_326243.1 487863 D 272635 CDS NP_326244.1 15828884 911520 489301..490623 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P18766 (AMIF_STRPN) Blastp2 P=5e-44 C=42% Pfscan: pos. 78-100 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 283-355 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 76-359 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 262-314 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 83-90 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 283-297 PS00211 | ABC_TRANSPORTER ABC transporters family signature; oligopeptide ABC transporter ATP-binding protein OppF 490623 911520 MYPU_4130 Mycoplasma pulmonis UAB CTIP oligopeptide ABC transporter ATP-binding protein OppF NP_326244.1 489301 D 272635 CDS NP_326245.1 15828885 911670 490641..497375 1 NC_002771.1 no similarity found; Pfscan: pos. 2203-2210 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 497375 911670 MYPU_4140 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326245.1 490641 D 272635 CDS NP_326246.1 15828886 911341 497382..500096 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q52268 Blast2p P=3e-8 C=10% Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 500096 911341 MYPU_4150 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326246.1 497382 D 272635 CDS NP_326247.1 15828887 911643 500508..501926 1 NC_002771.1 no similarity found; hypothetical protein 501926 911643 MYPU_4160 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326247.1 500508 D 272635 CDS NP_326248.1 15828888 911386 501938..502915 1 NC_002771.1 no similarity found; hypothetical protein 502915 911386 MYPU_4170 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326248.1 501938 D 272635 CDS NP_326249.1 15828889 910964 503241..504260 1 NC_002771.1 no similarity found; hypothetical protein 504260 910964 MYPU_4180 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326249.1 503241 D 272635 CDS NP_326250.1 15828890 911399 504664..504969 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:AAF06071 Blast2p P=4e-6 score=50 Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 504969 911399 MYPU_4190 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326250.1 504664 D 272635 CDS NP_326251.1 15828891 911375 505069..506805 1 NC_002771.1 no similarity found; hypothetical protein 506805 911375 MYPU_4200 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326251.1 505069 D 272635 CDS NP_326252.1 15828892 911559 complement(507153..508187) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P56696 (CIQ4_HUMAN) Blastp2 P=3e-06 C=16% Pfscan: pos. 45-285 PS50266 | CATION_CHANNEL_TM Cation channels, 6TM region (non-ligand gated) pos. 228-285 PS50265 | CHANNEL_PORE_K Pore region of potassium channels. pos. 46-281 PF00520 | ION_TRANS Ion transport protein pos. 149-333 PF00914 | CNG_MEMBRANE Transmembrane region cyclic Nucleotide Gated Channel (PDOC00691); potassium channel protein 508187 911559 MYPU_4210 Mycoplasma pulmonis UAB CTIP potassium channel protein NP_326252.1 507153 R 272635 CDS NP_326253.1 15828893 911607 complement(508259..509977) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47291 (Y045_MYCGE) Blastp2 P=1e-07 C=32%; hypothetical protein 509977 911607 MYPU_4220 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326253.1 508259 R 272635 CDS NP_326254.1 15828894 911364 complement(509967..510860) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47290 (POTC_MYCGE) Blastp2 P=2e-25 C=39% Pfscan: pos. 161-220 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inne; spermidine/putrescine ABC transporter permease 510860 911364 MYPU_4230 Mycoplasma pulmonis UAB CTIP spermidine/putrescine ABC transporter permease NP_326254.1 509967 R 272635 CDS NP_326255.1 15828895 910933 complement(510853..511692) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P75058 (POTB_MYCPN) Blastp2 P=7e-25 C=37% Pfscan: pos. 150-209 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inne pos. 115-124 PS00599 | AA_TRANSFER_CLASS_2 Aminotransferases class-II pyridoxal-phosphate attachment site pos. 161-189 PS00402 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inner membrane comp. sign; spermidine/putrescine ABC transporter permease 511692 910933 MYPU_4240 Mycoplasma pulmonis UAB CTIP spermidine/putrescine ABC transporter permease NP_326255.1 510853 R 272635 CDS NP_326256.1 15828896 911618 complement(511682..513058) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47288 (POTA_MYCGE) Blastp2 P=5e-51 C=38% Pfscan: pos. 47-68 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 241-313 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 45-317 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 219-272 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 52-59 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 241-255 PS00211 | ABC_TRANSPORTER ABC transporters family signature; spermidine/putrescine ABC transporter ATP-binding protein 513058 911618 MYPU_4250 Mycoplasma pulmonis UAB CTIP spermidine/putrescine ABC transporter ATP-binding protein NP_326256.1 511682 R 272635 CDS NP_326257.1 15828897 911629 complement(513181..513363) 1 NC_002771.1 no similarity found; hypothetical protein 513363 911629 MYPU_4260 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326257.1 513181 R 272635 CDS NP_326258.1 15828898 911564 complement(513418..514332) 1 NC_002771.1 no similarity found; hypothetical protein 514332 911564 MYPU_4270 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326258.1 513418 R 272635 CDS NP_326259.1 15828899 911705 complement(514569..516656) 1 NC_002771.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 516656 911705 MYPU_4280 Mycoplasma pulmonis UAB CTIP elongation factor G NP_326259.1 514569 R 272635 CDS NP_326260.1 15828900 911412 complement(516650..517120) 1 NC_002771.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 517120 911412 MYPU_4290 Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S7 NP_326260.1 516650 R 272635 CDS NP_326261.1 15828901 911313 complement(517177..517590) 1 NC_002771.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 517590 rpsL 911313 rpsL Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S12 NP_326261.1 517177 R 272635 CDS NP_326262.1 15828902 910939 517786..518973 1 NC_002771.1 identified by sequence similarity; probable; similar to TREMBL:O85798 (O85798) Blastp2 P=0 C=65% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction modification enzyme subunit S2A 518973 910939 MYPU_4310 Mycoplasma pulmonis UAB CTIP restriction modification enzyme subunit S2A NP_326262.1 517786 D 272635 CDS NP_326263.1 15828903 911640 518966..521926 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50357 Blastp2 P=0.0 Id=96% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction modification enzyme subunit R2 521926 911640 MYPU_4320 Mycoplasma pulmonis UAB CTIP restriction modification enzyme subunit R2 NP_326263.1 518966 D 272635 CDS NP_326264.1 15828904 911668 521930..523492 1 NC_002771.1 identified by sequence similarity; similar to TREMBL O30381 Blastp2 P=0.0 Id=97% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction modification enzyme subunit M2 523492 911668 MYPU_4330 Mycoplasma pulmonis UAB CTIP restriction modification enzyme subunit M2 NP_326264.1 521930 D 272635 CDS NP_326265.1 15828905 911515 complement(523537..524547) 1 NC_002771.1 identified by sequence similarity; probable; similar to TREMBL:Q50359 (Q50359) Blastp2 P=0 C=95% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction modification enzyme subunit S2B 524547 911515 MYPU_4340 Mycoplasma pulmonis UAB CTIP restriction modification enzyme subunit S2B NP_326265.1 523537 R 272635 CDS NP_326266.1 15828906 911446 complement(524831..525637) 1 NC_002771.1 identified by sequence similarity; probable; similar to TREMBL:O30383 (O30383) Blastp2 P=0 C=89% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; hypothetical protein 525637 911446 MYPU_4350 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326266.1 524831 R 272635 CDS NP_326267.1 15828907 911458 526174..526716 1 NC_002771.1 no similarity found Pfscan: pos. 21-31 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 526716 911458 MYPU_4360 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326267.1 526174 D 272635 CDS NP_326268.1 15828908 911479 526727..529102 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q25662 (Q25662) Blastp2 P=9e-13 C=41%; hypothetical protein 529102 911479 MYPU_4370 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326268.1 526727 D 272635 CDS NP_326269.1 15828909 911468 529275..531653 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q49096 (Q49096) Blastp2 P=5e-14 C=7% Pfscan: pos. 83-170 PS50099 | PRO_RICH Proline-rich region.; hypothetical protein 531653 911468 MYPU_4380 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326269.1 529275 D 272635 CDS NP_326270.1 15828910 911314 complement(531684..533684) 1 NC_002771.1 no similarity found; hypothetical protein 533684 911314 MYPU_4390 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326270.1 531684 R 272635 CDS NP_326271.1 15828911 911703 533748..534791 1 NC_002771.1 identified by sequence similarity; possible; similar to =TREMBL:CAB3166 Blastp2 P=6e-15 score=82; polymorphism postion 534022 bp: TGAAATA(G/A)CAAGTAC 7 sequences with A, 2 sequences with G; oxygenase 534791 911703 MYPU_4400 Mycoplasma pulmonis UAB CTIP oxygenase NP_326271.1 533748 D 272635 CDS NP_326272.1 15828912 911551 534748..535083 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9WY55 (Q9WY55) Blastp2 P=9e-10 C=51%; glycine cleavage system H protein 535083 911551 MYPU_4410 Mycoplasma pulmonis UAB CTIP glycine cleavage system H protein NP_326272.1 534748 D 272635 CDS NP_326273.1 15828913 911489 535086..535934 1 NC_002771.1 no similarity found; hypothetical protein 535934 911489 MYPU_4420 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326273.1 535086 D 272635 CDS NP_326274.1 15828914 911697 535953..536987 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P75394 (LPLA_MYCPN) Blastp2 P=2e-28 C=46%; lipoate-protein ligase A 536987 911697 MYPU_4430 Mycoplasma pulmonis UAB CTIP lipoate-protein ligase A NP_326274.1 535953 D 272635 CDS NP_326275.1 15828915 911661 537095..538621 1 NC_002771.1 no similarity found Pfscan:; hypothetical protein 538621 911661 MYPU_4440 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326275.1 537095 D 272635 CDS NP_326276.1 15828916 911445 538572..539093 1 NC_002771.1 no similarity found; hypothetical protein 539093 911445 MYPU_4450 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326276.1 538572 D 272635 CDS NP_326277.1 15828917 911447 539080..539904 1 NC_002771.1 no similarity found; hypothetical protein 539904 911447 MYPU_4460 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326277.1 539080 D 272635 CDS NP_326278.1 15828918 911483 539919..540539 1 NC_002771.1 no similarity found; hypothetical protein 540539 911483 MYPU_4470 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326278.1 539919 D 272635 CDS NP_326279.1 15828919 911522 540523..543261 1 NC_002771.1 no similarity found; hypothetical protein 543261 911522 MYPU_4480 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326279.1 540523 D 272635 CDS NP_326280.1 15828920 911609 543263..544804 1 NC_002771.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 544804 911609 MYPU_4490 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit alpha NP_326280.1 543263 D 272635 CDS NP_326281.1 15828921 911543 544792..546198 1 NC_002771.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 546198 911543 MYPU_4500 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit beta NP_326281.1 544792 D 272635 CDS NP_326282.1 15828922 911612 546220..547581 1 NC_002771.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 547581 911612 MYPU_4510 Mycoplasma pulmonis UAB CTIP glycyl-tRNA synthetase NP_326282.1 546220 D 272635 CDS NP_326283.1 15828923 911532 complement(547565..547768) 1 NC_002771.1 no similarity found; hypothetical protein 547768 911532 MYPU_4520 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326283.1 547565 R 272635 CDS NP_326284.1 15828924 911523 547581..549389 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P71481 (PRIM_LEGPN) Blastp2 P=2e-46 C=33%; DNA primase 549389 911523 MYPU_4530 Mycoplasma pulmonis UAB CTIP DNA primase NP_326284.1 547581 D 272635 CDS NP_326285.1 15828925 911459 549328..550713 1 NC_002771.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 550713 911459 MYPU_4540 Mycoplasma pulmonis UAB CTIP RNA polymerase sigma factor NP_326285.1 549328 D 272635 CDS NP_326286.1 15828926 911698 550896..551480 1 NC_002771.1 no similarity found Pfscan: pos. 16-26 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 551480 911698 MYPU_4550 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326286.1 550896 D 272635 CDS NP_326287.1 15828927 911568 551711..552466 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P53434 (YRP2_LISMO) Blastp2 P=6e-11 C=38%; hypothetical protein 552466 911568 MYPU_4560 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326287.1 551711 D 272635 CDS NP_326288.1 15828928 911529 552479..552967 1 NC_002771.1 no similarity found; hypothetical protein 552967 911529 MYPU_4570 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326288.1 552479 D 272635 CDS NP_326289.1 15828929 911512 553094..553840 1 NC_002771.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 553840 tpiA 911512 tpiA Mycoplasma pulmonis UAB CTIP triosephosphate isomerase NP_326289.1 553094 D 272635 CDS NP_326290.1 15828930 911319 553843..555360 1 NC_002771.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 555360 911319 MYPU_4590 Mycoplasma pulmonis UAB CTIP phosphoglyceromutase NP_326290.1 553843 D 272635 CDS NP_326291.1 15828931 911372 555480..556022 1 NC_002771.1 no similarity found; hypothetical protein 556022 911372 MYPU_4600 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326291.1 555480 D 272635 CDS NP_326292.1 15828932 911380 555947..557218 1 NC_002771.1 identified by sequence similarity; unknown; similar to SWISSPROT:P47558 (Y316_MYCGE) Blastp2 P=0.029 score=40; hypothetical protein 557218 911380 MYPU_4610 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326292.1 555947 D 272635 CDS NP_326293.1 15828933 911425 557260..558204 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P54459 (YQEN_BACSU) Blastp2 P=1e-09 C=39%; hypothetical protein 558204 911425 MYPU_4620 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326293.1 557260 D 272635 CDS NP_326294.1 15828934 911610 558209..559795 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q99040 (DEXB_STRMU) Blastp2 P=3e-15 C=38%; glucan 1,6-alpha-glucosidase 559795 911610 MYPU_4630 Mycoplasma pulmonis UAB CTIP glucan 1,6-alpha-glucosidase NP_326294.1 558209 D 272635 CDS NP_326295.1 15828935 911513 559990..561342 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O23037 (O23037) Blastp2 P=1e-07 C=27%; hypothetical protein 561342 911513 MYPU_4640 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326295.1 559990 D 272635 CDS NP_326296.1 15828936 910911 561804..563672 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q25662 (Q25662) Blastp2 P=1e-08 C=25% Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 563672 910911 MYPU_4650 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326296.1 561804 D 272635 CDS NP_326297.1 15828937 911325 563924..565411 1 NC_002771.1 no similarity found; hypothetical protein 565411 911325 MYPU_4660 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326297.1 563924 D 272635 CDS NP_326298.1 15828938 911317 complement(565891..566244) 1 NC_002771.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 566244 rplS 911317 rplS Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L19 NP_326298.1 565891 R 272635 CDS NP_326299.1 15828939 910938 complement(566234..566911) 1 NC_002771.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 566911 trmD 910938 trmD Mycoplasma pulmonis UAB CTIP tRNA (guanine-N(1)-)-methyltransferase NP_326299.1 566234 R 272635 CDS NP_326300.1 15828940 911404 complement(566911..567177) 1 NC_002771.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 567177 rpsP 911404 rpsP Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S16 NP_326300.1 566911 R 272635 CDS NP_326301.1 15828941 911469 567345..567896 1 NC_002771.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 567896 911469 MYPU_4700 Mycoplasma pulmonis UAB CTIP inorganic pyrophosphatase NP_326301.1 567345 D 272635 CDS NP_326302.1 15828942 911549 567948..569825 1 NC_002771.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 569825 911549 MYPU_4710 Mycoplasma pulmonis UAB CTIP DNA topoisomerase I NP_326302.1 567948 D 272635 CDS NP_326303.1 15828943 910953 complement(569882..570685) 1 NC_002771.1 identified by sequence similarity; similar to SWISSPROT:P25201 (MTA1_ACICA) Blastp2 P=0.001 score=44 Pfscan: pos. 61-162 PS50193 | SAM_BIND SAM (and some other nucleotide) binding motif. pos. 134-140 PS00092 | N6_MTASE N-6 Adenine-specific DNA methylases signature; DNA methylase 570685 910953 MYPU_4720 Mycoplasma pulmonis UAB CTIP DNA methylase NP_326303.1 569882 R 272635 CDS NP_326304.1 15828944 910951 complement(570749..571423) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q9WZY5 (Q9WZY5) Blastp2 P=2e-13 C=48%; hypothetical protein 571423 910951 MYPU_4730 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326304.1 570749 R 272635 CDS NP_326305.1 15828945 910945 571534..572505 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P44937 (CDSA_HAEIN) Blastp2 P=2e-12 C=22%; phosphatidate cytidylyltransferase 572505 910945 MYPU_4740 Mycoplasma pulmonis UAB CTIP phosphatidate cytidylyltransferase NP_326305.1 571534 D 272635 CDS NP_326306.1 15828946 911619 572569..573129 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47275 (Y029_MYCGE) Blastp2 P=9e-09 C=40%; hypothetical protein 573129 911619 MYPU_4750 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326306.1 572569 D 272635 CDS NP_326307.1 15828947 911369 complement(573267..574949) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47606 (Y366_MYCGE) Blastp2 P=5e-26 C=44%; hypothetical protein 574949 911369 MYPU_4760 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326307.1 573267 R 272635 CDS NP_326308.1 15828948 910937 complement(575089..575940) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P75227 (Y373_MYCPN) Blastp2 P=6e-12 C=35%; hypothetical protein 575940 910937 MYPU_4770 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326308.1 575089 R 272635 CDS NP_326309.1 15828949 911688 complement(576057..578309) 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:O96246 (O96246) Blastp2 P=1e-06 C=16%; Pfscan: pos. 11-21 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; polymorphism in the promoter (578371 bp): 2 sequences with (A)40, 2 sequences with (A)39, 1 sequence with (A)36, 1 sequence with (A)41, 1 sequence with (A)44; lipoprotein 578309 911688 MYPU_4780 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326309.1 576057 R 272635 CDS NP_326310.1 15828950 911443 complement(578566..580980) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O97291 (O97291) Blastp2 P=5e-07 C=32% Pfscan: pos. 50-57 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 580980 911443 MYPU_4790 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326310.1 578566 R 272635 CDS NP_326311.1 15828951 910955 complement(580982..582745) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P40814 (T3MO_SALTY) Blastp2 P=8e-41 C=38%, polymorphism position 255778 bp: 3 sequences with (GA)12, 2 sequences with (GA)13 and 1 sequence with (GA)14; type III restriction-modification system: methylase 582745 910955 MYPU_4800 Mycoplasma pulmonis UAB CTIP type III restriction-modification system: methylase NP_326311.1 580982 R 272635 CDS NP_326312.1 15828952 911720 complement(582966..583874) 1 NC_002771.1 no similarity found ; Pfscan: pos. 102-130 PF00230 | MIP Major intrinsic protein (PDOC00193); transporter 583874 911720 MYPU_4810 Mycoplasma pulmonis UAB CTIP transporter NP_326312.1 582966 R 272635 CDS NP_326313.1 15828953 910952 complement(583874..586147) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O96246 (O96246) Blastp2 P=5e-09 C=24% Pfscan: pos. 26-36 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 586147 910952 MYPU_4820 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326313.1 583874 R 272635 CDS NP_326314.1 15828954 910956 586416..587420 1 NC_002771.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 587420 910956 MYPU_4830 Mycoplasma pulmonis UAB CTIP nicotinate phosphoribosyltransferase NP_326314.1 586416 D 272635 CDS NP_326315.1 15828955 910949 complement(587696..590431) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q26223 (Q26223) Blastp2 P=2e-09 C=20%; hypothetical protein 590431 910949 MYPU_4840 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326315.1 587696 R 272635 CDS NP_326316.1 15828956 910962 complement(590450..591694) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P22326 (SYY1_BACSU) Blastp2 P=2e-74 C=60%; tyrosyl-tRNA synthetase 591694 910962 MYPU_4850 Mycoplasma pulmonis UAB CTIP tyrosyl-tRNA synthetase NP_326316.1 590450 R 272635 CDS NP_326317.1 15828957 910958 complement(591694..592284) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O34943 (O34943) Blastp2 P=1e-06 C=41%; phenylalanyl-tRNA synthetase subunit beta 592284 910958 MYPU_4860 Mycoplasma pulmonis UAB CTIP phenylalanyl-tRNA synthetase subunit beta NP_326317.1 591694 R 272635 CDS NP_326318.1 15828958 910963 593025..594482 1 NC_002771.1 no similarity found; Pfscan: pos. 17-27 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 594482 910963 MYPU_4870 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326318.1 593025 D 272635 CDS NP_326319.1 15828959 911621 complement(594541..595587) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P54518 (YQHT_BACSU) Blastp2 P=2e-64 C=58% Pfscan: pos. 121-348 PF00557 | PEP_M24 metallopeptidase M24 (PDOC00417) (PDOC00575) pos. 282-294 PS00491 | PROLINE_PEPTIDASE Aminopeptidase P and proline dipeptidase signature; XAA-Pro aminopeptidase 595587 911621 MYPU_4880 Mycoplasma pulmonis UAB CTIP XAA-Pro aminopeptidase NP_326319.1 594541 R 272635 CDS NP_326320.1 15828960 910960 complement(595639..595791) 1 NC_002771.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 595791 rpmG 910960 rpmG Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L33 NP_326320.1 595639 R 272635 CDS NP_326321.1 15828961 910961 complement(595890..597419) 1 NC_002771.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 597419 metG 910961 metG Mycoplasma pulmonis UAB CTIP methionyl-tRNA synthetase NP_326321.1 595890 R 272635 CDS NP_326322.1 15828962 910959 complement(597583..598755) 1 NC_002771.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 598755 910959 MYPU_4910 Mycoplasma pulmonis UAB CTIP cell division protein FtsZ NP_326322.1 597583 R 272635 CDS NP_326323.1 15828963 910957 complement(598792..600024) 1 NC_002771.1 no similarity found; hypothetical protein 600024 910957 MYPU_4920 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326323.1 598792 R 272635 CDS NP_326324.1 15828964 911261 complement(600039..600938) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9Z8C2 Blastp2 P=2e-31 score=136; methyltransferase 600938 911261 MYPU_4930 Mycoplasma pulmonis UAB CTIP methyltransferase NP_326324.1 600039 R 272635 CDS NP_326325.1 15828965 911264 complement(600938..601402) 1 NC_002771.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 601402 911264 MYPU_4940 Mycoplasma pulmonis UAB CTIP cell division protein MraZ NP_326325.1 600938 R 272635 CDS NP_326326.1 15828966 911263 601696..602130 1 NC_002771.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 602130 rplM 911263 rplM Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L13 NP_326326.1 601696 D 272635 CDS NP_326327.1 15828967 911259 602130..602540 1 NC_002771.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 602540 rpsI 911259 rpsI Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S9 NP_326327.1 602130 D 272635 CDS NP_326328.1 15828968 911255 602768..604303 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47433 (Y187_MYCGE) Blastp2 P=2e-28 C=30% Pfscan: pos. 41-66 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 317-389 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 39-393 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 295-348 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 46-53 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 317-331 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 604303 911255 MYPU_4970 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_326328.1 602768 D 272635 CDS NP_326329.1 15828969 911262 604260..605270 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P47434 (Y188_MYCGE) Blastp2 P=2e-14 C=34%; ABC transporter permease 605270 911262 MYPU_4980 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_326329.1 604260 D 272635 CDS NP_326330.1 15828970 911256 605263..606096 1 NC_002771.1 identified by sequence similarity; similar to SWISSPROT:P47435 (Y189_MYCGE) Blast2p P=1e-4 score=47 Tmpred prediction: 7 transmembrane helices; ABC transporter permease 606096 911256 MYPU_4990 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_326330.1 605263 D 272635 CDS NP_326331.1 15828971 911253 complement(606491..608701) 1 NC_002771.1 no similarity found Pfscan: pos. 290-306 PS50099 | PRO_RICH Proline-rich region.; hypothetical protein 608701 911253 MYPU_5000 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326331.1 606491 R 272635 CDS NP_326332.1 15828972 911258 complement(608685..609158) 1 NC_002771.1 no similarity found; hypothetical protein 609158 911258 MYPU_5010 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326332.1 608685 R 272635 CDS NP_326333.1 15828973 911251 complement(609161..610141) 1 NC_002771.1 no similarity found; hypothetical protein 610141 911251 MYPU_5020 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326333.1 609161 R 272635 CDS NP_326334.1 15828974 911250 complement(610095..611573) 1 NC_002771.1 no similarity found; hypothetical protein 611573 911250 MYPU_5030 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326334.1 610095 R 272635 CDS NP_326335.1 15828975 911254 complement(611590..613995) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q49097 (Q49097) Blastp2 P=2e-28 C=14% Pfscan: pos. 17-27 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 613995 911254 MYPU_5040 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326335.1 611590 R 272635 CDS NP_326336.1 15828976 911247 complement(614032..616533) 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q49096 (Q49096) Blastp2 P=2e-14 C=6% Pfscan: pos. 82-139 PS50099 | PRO_RICH Proline-rich region.; hypothetical protein 616533 911247 MYPU_5050 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326336.1 614032 R 272635 CDS NP_326337.1 15828977 911252 616931..617368 1 NC_002771.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 617368 911252 MYPU_5060 Mycoplasma pulmonis UAB CTIP methionine sulfoxide reductase B NP_326337.1 616931 D 272635 CDS NP_326338.1 15828978 911248 complement(617527..618960) 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:AAD53524 Blastp2 P=1e-7 score=58; hypothetical protein 618960 911248 MYPU_5070 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326338.1 617527 R 272635 CDS NP_326339.1 15828979 911244 complement(619485..621527) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50274 P=5e-4 score=46 Pfscan: pos. 18-28 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 621527 911244 MYPU_5080 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326339.1 619485 R 272635 CDS NP_326340.1 15828980 911246 complement(621670..623532) 1 NC_002771.1 no similarity found; Pfscan: pos. 18-28 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 623532 911246 MYPU_5090 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326340.1 621670 R 272635 CDS NP_326341.1 15828981 911249 complement(623713..623952) 1 NC_002771.1 no similarity found; hypothetical protein 623952 911249 MYPU_5100 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326341.1 623713 R 272635 CDS NP_326342.1 15828982 911245 complement(624200..626047) 1 NC_002771.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 626047 911245 MYPU_5110 Mycoplasma pulmonis UAB CTIP transketolase NP_326342.1 624200 R 272635 CDS NP_326343.1 15828983 911242 complement(626049..626345) 1 NC_002771.1 no similarity found; hypothetical protein 626345 911242 MYPU_5120 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326343.1 626049 R 272635 CDS NP_326344.1 15828984 911243 complement(626345..626908) 1 NC_002771.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 626908 911243 MYPU_5130 Mycoplasma pulmonis UAB CTIP elongation factor P NP_326344.1 626345 R 272635 CDS NP_326345.1 15828985 911241 complement(627035..628324) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9WZU9 Blastp2 P=2e-23 score=110; hemolysin C 628324 911241 MYPU_5140 Mycoplasma pulmonis UAB CTIP hemolysin C NP_326345.1 627035 R 272635 CDS NP_326346.1 15828986 911237 complement(628335..629702) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P37469 (DNAC_BACSU) Blastp2 P=2e-70 C=52%; replicative DNA helicase 629702 911237 MYPU_5150 Mycoplasma pulmonis UAB CTIP replicative DNA helicase NP_326346.1 628335 R 272635 CDS NP_326347.1 15828987 911240 complement(629686..630156) 1 NC_002771.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 630156 rplI 911240 rplI Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L9 NP_326347.1 629686 R 272635 CDS NP_326348.1 15828988 911236 complement(630119..632101) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P37484 (YYBT_BACSU) Blastp2 P=4e-47 C=39% Pfscan: pos. 338-647 PF01368 | DHH DHH family; hypothetical protein 632101 911236 MYPU_5170 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326348.1 630119 R 272635 CDS NP_326349.1 15828989 911239 632292..633662 1 NC_002771.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 633662 eno 911239 eno Mycoplasma pulmonis UAB CTIP phosphopyruvate hydratase NP_326349.1 632292 D 272635 CDS NP_326350.1 15828990 911235 complement(633790..636318) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P36772 (LON_BACBR) Blastp2 P=0 C=56%; heat shock ATP-dependent protease 636318 911235 MYPU_5190 Mycoplasma pulmonis UAB CTIP heat shock ATP-dependent protease NP_326350.1 633790 R 272635 CDS NP_326351.1 15828991 911234 636795..637793 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50269 (Q50269) Blastp2 P=3e-12 C=19% ; Pfscan: pos.20-30 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein D 637793 911234 MYPU_5200 Mycoplasma pulmonis UAB CTIP lipoprotein D NP_326351.1 636795 D 272635 CDS NP_326352.1 15828992 911233 complement(638031..639440) 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q50274 (Q50274) Blastp2 P=7e-09 C=7% ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; hypothetical protein 639440 911233 MYPU_5210 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326352.1 638031 R 272635 CDS NP_326353.1 15828993 911232 complement(639404..640114) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50274 Blastp2 P=3e-50 Id=46% ; Pfscan : 18-28 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein B 640114 911232 MYPU_5220 Mycoplasma pulmonis UAB CTIP lipoprotein B NP_326353.1 639404 R 272635 CDS NP_326354.1 15828994 911231 <640365..641210 1 NC_002771.1 identified by sequence similarity, similar to trEMBL:Q50279 blastp2 P=0.67 score=35; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein VSAA (fragment) 641210 911231 MYPU_5230 Mycoplasma pulmonis UAB CTIP lipoprotein VSAA (fragment) NP_326354.1 <640365 D 272635 CDS NP_326355.1 15828995 911230 <641512..642636 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50280 Blastp2 P=2e-14 Id=38% ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein VSAF (fragment) 642636 911230 MYPU_5240 Mycoplasma pulmonis UAB CTIP lipoprotein VSAF (fragment) NP_326355.1 <641512 D 272635 CDS NP_326356.1 15828996 911225 <643145..645646 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50280 Blastp2 P=1e-80 Id=83% ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein VSAC (fragment) 645646 911225 MYPU_5250 Mycoplasma pulmonis UAB CTIP lipoprotein VSAC (fragment) NP_326356.1 <643145 D 272635 CDS NP_326357.1 15828997 911227 complement(645834..>646778) 1 NC_002771.1 identified by sequence similarity; probable; similar to TREMBL:Q50277 (Q50277) Blastp2 P=0 C=76% ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein VSAE (fragment) >646778 911227 MYPU_5260 Mycoplasma pulmonis UAB CTIP lipoprotein VSAE (fragment) NP_326357.1 645834 R 272635 CDS NP_326358.1 15828998 911238 complement(647323..>648615) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50278 Blastp2 P=1e-21 Id=41% ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein VSAG (fragment) >648615 911238 MYPU_5270 Mycoplasma pulmonis UAB CTIP lipoprotein VSAG (fragment) NP_326358.1 647323 R 272635 CDS NP_326359.1 15828999 911228 649088..651607 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50279 Blastp2 P=e-160 Id=45% ; Pfscan: pos. 20-30 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein VSAI 651607 911228 MYPU_5280 Mycoplasma pulmonis UAB CTIP lipoprotein VSAI NP_326359.1 649088 D 272635 CDS NP_326360.1 15829000 911229 complement(652745..>652873) 1 NC_002771.1 identified by sequence similarity, similar to trEMBL:Q50322 blastp2 P=2e-8 score=55; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein VSAH (fragment) >652873 911229 MYPU_5290 Mycoplasma pulmonis UAB CTIP lipoprotein VSAH (fragment) NP_326360.1 652745 R 272635 CDS NP_326361.1 15829001 911226 653131..654867 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q50274 (Q50274) Blastp2 P=0 C=38% ; Pfscan: pos. 14-24 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; lipoprotein 654867 911226 MYPU_5300 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326361.1 653131 D 272635 CDS NP_326362.1 15829002 911222 complement(656086..656910) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P39776 (CODV_BACSU) Blastp2 P=2e-11 C=30% ; Gene Rearrangements in the vsa Locus of Mycoplasma pulmonis; Xuejun Shen, Juliann Gumulak, Huilan Yu, C. Todd French, Nianxiang Zou, and Kevin Dybvig; J. Bacteriol. 2000; 182 2900-2908; integrase/recombinase 656910 911222 MYPU_5310 Mycoplasma pulmonis UAB CTIP integrase/recombinase NP_326362.1 656086 R 272635 CDS NP_326363.1 15829003 911220 complement(656947..657831) 1 NC_002771.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 657831 tsf 911220 tsf Mycoplasma pulmonis UAB CTIP elongation factor Ts NP_326363.1 656947 R 272635 CDS NP_326364.1 15829004 911223 complement(657834..658826) 1 NC_002771.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 658826 rpsB 911223 rpsB Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S2 NP_326364.1 657834 R 272635 CDS NP_326365.1 15829005 911221 659041..659532 1 NC_002771.1 no similarity found; hypothetical protein 659532 911221 MYPU_5340 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326365.1 659041 D 272635 CDS NP_326366.1 15829006 911219 659525..660424 1 NC_002771.1 no similarity found; hypothetical protein 660424 911219 MYPU_5350 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326366.1 659525 D 272635 CDS NP_326367.1 15829007 911224 complement(660555..661862) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P37545 (YABD_BACSU) Blastp2 P=1e-37 C=33% Pfscan: pos. 191-434 PF01026 | UPF0006 Uncharacterized protein family (PDOC00836) pos. 305-315 PS01090 | UPF0006_2 Uncharacterized protein family UPF0006 signature 2; hypothetical protein 661862 911224 MYPU_5360 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326367.1 660555 R 272635 CDS NP_326368.1 15829008 911218 complement(661953..662492) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P47470 (DYR_MYCGE) Blastp2 P=6e-39 C=64%; dihydrofolate reductase 662492 911218 MYPU_5370 Mycoplasma pulmonis UAB CTIP dihydrofolate reductase NP_326368.1 661953 R 272635 CDS NP_326369.1 15829009 911257 complement(662446..663306) 1 NC_002771.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 663306 thyA 911257 thyA Mycoplasma pulmonis UAB CTIP thymidylate synthase NP_326369.1 662446 R 272635 CDS NP_326370.1 15829010 911217 663546..664571 1 NC_002771.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 664571 nrdF 911217 nrdF Mycoplasma pulmonis UAB CTIP ribonucleotide-diphosphate reductase subunit beta NP_326370.1 663546 D 272635 CDS NP_326371.1 15829011 911214 664575..665030 1 NC_002771.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 665030 nrdI 911214 nrdI Mycoplasma pulmonis UAB CTIP ribonucleotide reductase stimulatory protein NP_326371.1 664575 D 272635 CDS NP_326372.1 15829012 911209 665064..667199 1 NC_002771.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 667199 911209 MYPU_5410 Mycoplasma pulmonis UAB CTIP ribonucleotide-diphosphate reductase subunit alpha NP_326372.1 665064 D 272635 CDS NP_326373.1 15829013 911212 667230..667901 1 NC_002771.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 667901 911212 MYPU_5420 Mycoplasma pulmonis UAB CTIP 16S ribosomal RNA methyltransferase RsmE NP_326373.1 667230 D 272635 CDS NP_326374.1 15829014 911207 667943..668746 1 NC_002771.1 no similarity found; hypothetical protein 668746 911207 MYPU_5430 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326374.1 667943 D 272635 CDS NP_326375.1 15829015 911215 complement(668819..669676) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47507 (Y265_MYCGE) Blastp2 P=2e-30 C=47% Pfscan: pos. 11-272 PF00592 | DUF3 Domain of Unknown Function 3; hypothetical protein 669676 911215 MYPU_5440 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326375.1 668819 R 272635 CDS NP_326376.1 15829016 911208 complement(669816..674096) 1 NC_002771.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 674096 911208 MYPU_5450 Mycoplasma pulmonis UAB CTIP DNA-directed RNA polymerase subunit beta' NP_326376.1 669816 R 272635 CDS NP_326377.1 15829017 911205 complement(674099..677749) 1 NC_002771.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 677749 rpoB 911205 rpoB Mycoplasma pulmonis UAB CTIP DNA-directed RNA polymerase subunit beta NP_326377.1 674099 R 272635 CDS NP_326378.1 15829018 911206 complement(677946..678680) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q9ZNH9 (Q9ZNH9) Blastp2 P=3e-16 C=45%; DNA processing protein SMF 678680 911206 MYPU_5470 Mycoplasma pulmonis UAB CTIP DNA processing protein SMF NP_326378.1 677946 R 272635 CDS NP_326379.1 15829019 911216 complement(678756..679595) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9WZW1 (Q9WZW1) Blastp2 P=2e-13 C=33%; hypothetical protein 679595 911216 MYPU_5480 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326379.1 678756 R 272635 CDS NP_326380.1 15829020 911204 complement(679679..680506) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P42962 (YCSE_BACSU) Blastp2 P=1e-13 C=42% Pfscan: pos. 10-262 PF00592 | DUF3 Domain of Unknown Function 3; hypothetical protein 680506 911204 MYPU_5490 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326380.1 679679 R 272635 CDS NP_326381.1 15829021 911213 complement(680490..681338) 1 NC_002771.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 681338 truB 911213 truB Mycoplasma pulmonis UAB CTIP tRNA pseudouridine synthase B NP_326381.1 680490 R 272635 CDS NP_326382.1 15829022 911200 complement(681949..682530) 1 NC_002771.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 682530 911200 MYPU_5510 Mycoplasma pulmonis UAB CTIP hypoxanthine-guanine phosphoribosyltransferase NP_326382.1 681949 R 272635 CDS NP_326383.1 15829023 911195 complement(682599..683249) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75396 (Y268_MYCPN) Blastp2 P=9e-21 C=50% Pfscan: pos. 7-14 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); deoxyguanosine kinase 683249 911195 MYPU_5520 Mycoplasma pulmonis UAB CTIP deoxyguanosine kinase NP_326383.1 682599 R 272635 CDS NP_326384.1 15829024 911193 complement(683261..683755) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P78019 (GREA_MYCPN) Blastp2 P=1e-30 C=63%; transcription elongation factor GreA 683755 911193 MYPU_5530 Mycoplasma pulmonis UAB CTIP transcription elongation factor GreA NP_326384.1 683261 R 272635 CDS NP_326385.1 15829025 911197 complement(683820..684500) 1 NC_002771.1 no similarity found; hypothetical protein 684500 911197 MYPU_5540 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326385.1 683820 R 272635 CDS NP_326386.1 15829026 911190 complement(684502..684840) 1 NC_002771.1 no similarity found Pfscan: pos. 29-84 GC0265 | CARBOXYLESTERASE_B Carboxylesterases type-B active site.; hypothetical protein 684840 911190 MYPU_5550 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326386.1 684502 R 272635 CDS NP_326387.1 15829027 911194 complement(684840..685280) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O34634 (YRRK_BACSU) Blastp2 P=4e-13 C=45%; hypothetical protein 685280 911194 MYPU_5560 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326387.1 684840 R 272635 CDS NP_326388.1 15829028 911196 complement(685273..687894) 1 NC_002771.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 687894 alaS 911196 alaS Mycoplasma pulmonis UAB CTIP alanyl-tRNA synthetase NP_326388.1 685273 R 272635 CDS NP_326389.1 15829029 911191 complement(687931..689046) 1 NC_002771.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 689046 mnmA 911191 mnmA Mycoplasma pulmonis UAB CTIP tRNA-specific 2-thiouridylase MnmA NP_326389.1 687931 R 272635 CDS NP_326390.1 15829030 911186 complement(689109..692795) 1 NC_002771.1 no similarity found; hypothetical protein 692795 911186 MYPU_5590 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326390.1 689109 R 272635 CDS NP_326391.1 15829031 911192 complement(693042..693404) 1 NC_002771.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 693404 rplQ 911192 rplQ Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L17 NP_326391.1 693042 R 272635 CDS NP_326392.1 15829032 911189 complement(693404..694405) 1 NC_002771.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 694405 911189 MYPU_5610 Mycoplasma pulmonis UAB CTIP DNA-directed RNA polymerase subunit alpha NP_326392.1 693404 R 272635 CDS NP_326393.1 15829033 911188 complement(694410..694820) 1 NC_002771.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 694820 911188 MYPU_5620 Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S11 NP_326393.1 694410 R 272635 CDS NP_326394.1 15829034 911187 complement(694824..695222) 1 NC_002771.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 695222 rpsM 911187 rpsM Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S13 NP_326394.1 694824 R 272635 CDS NP_326395.1 15829035 911185 complement(695229..695342) 1 NC_002771.1 identified by sequence similarity; similar to SWISSPROT:P46361 (RL36_HAEIN) Blast2p P=3e-4 score=41; ribosomal protein L36 695342 911185 MYPU_5640 Mycoplasma pulmonis UAB CTIP ribosomal protein L36 NP_326395.1 695229 R 272635 CDS NP_326396.1 15829036 911198 complement(695425..695643) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P38037 (IF1_MYCSP) Blastp2 P=3e-16 C=72%; translation initiation factor IF-1 695643 911198 MYPU_5650 Mycoplasma pulmonis UAB CTIP translation initiation factor IF-1 NP_326396.1 695425 R 272635 CDS NP_326397.1 15829037 911181 complement(695643..696392) 1 NC_002771.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 696392 911181 MYPU_5660 Mycoplasma pulmonis UAB CTIP methionine aminopeptidase NP_326397.1 695643 R 272635 CDS NP_326398.1 15829038 911183 complement(696392..697036) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O51378 (KAD_BORBU) Blastp2 P=2e-36 C=59%; adenylate kinase 697036 911183 MYPU_5670 Mycoplasma pulmonis UAB CTIP adenylate kinase NP_326398.1 696392 R 272635 CDS NP_326399.1 15829039 911182 complement(697030..698454) 1 NC_002771.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 698454 secY 911182 secY Mycoplasma pulmonis UAB CTIP preprotein translocase subunit SecY NP_326399.1 697030 R 272635 CDS NP_326400.1 15829040 911179 complement(698457..698894) 1 NC_002771.1 late assembly protein; 50S ribosomal protein L15 698894 rplO 911179 rplO Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L15 NP_326400.1 698457 R 272635 CDS NP_326401.1 15829041 911180 complement(698908..699597) 1 NC_002771.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 699597 rpsE 911180 rpsE Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S5 NP_326401.1 698908 R 272635 CDS NP_326402.1 15829042 911177 complement(699597..699953) 1 NC_002771.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 699953 rplR 911177 rplR Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L18 NP_326402.1 699597 R 272635 CDS NP_326403.1 15829043 911176 complement(699966..700505) 1 NC_002771.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 700505 rplF 911176 rplF Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L6 NP_326403.1 699966 R 272635 CDS NP_326404.1 15829044 911211 complement(700509..700907) 1 NC_002771.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 700907 rpsH 911211 rpsH Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S8 NP_326404.1 700509 R 272635 CDS NP_326405.1 15829045 911173 complement(700911..701096) 1 NC_002771.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 701096 rpsN 911173 rpsN Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S14 NP_326405.1 700911 R 272635 CDS NP_326406.1 15829046 911175 complement(701106..701651) 1 NC_002771.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 701651 rplE 911175 rplE Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L5 NP_326406.1 701106 R 272635 CDS NP_326407.1 15829047 911172 complement(701654..701980) 1 NC_002771.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 701980 rplX 911172 rplX Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L24 NP_326407.1 701654 R 272635 CDS NP_326408.2 161723292 911169 complement(701991..702359) 1 NC_002771.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 702359 rplN 911169 rplN Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L14 NP_326408.2 701991 R 272635 CDS NP_326409.1 15829049 911170 complement(702361..702627) 1 NC_002771.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 702627 rpsQ 911170 rpsQ Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S17 NP_326409.1 702361 R 272635 CDS NP_326410.1 15829050 911174 complement(702627..702824) 1 NC_002771.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 702824 911174 MYPU_5790 Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L29 NP_326410.1 702627 R 272635 CDS NP_326411.1 15829051 911171 complement(702826..703254) 1 NC_002771.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 703254 rplP 911171 rplP Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L16 NP_326411.1 702826 R 272635 CDS NP_326412.1 15829052 911167 complement(703254..703907) 1 NC_002771.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 703907 rpsC 911167 rpsC Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S3 NP_326412.1 703254 R 272635 CDS NP_326413.1 15829053 911165 703891..704043 1 NC_002771.1 no similarity found; hypothetical protein 704043 911165 MYPU_5820 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326413.1 703891 D 272635 CDS NP_326414.1 15829054 911166 complement(703917..704249) 1 NC_002771.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 704249 rplV 911166 rplV Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L22 NP_326414.1 703917 R 272635 CDS NP_326415.1 15829055 911168 complement(704249..704524) 1 NC_002771.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 704524 rpsS 911168 rpsS Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S19 NP_326415.1 704249 R 272635 CDS NP_326416.1 15829056 911178 complement(704524..705369) 1 NC_002771.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 705369 rplB 911178 rplB Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L2 NP_326416.1 704524 R 272635 CDS NP_326417.1 15829057 911184 complement(705441..705905) 1 NC_002771.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 705905 rplW 911184 rplW Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L23 NP_326417.1 705441 R 272635 CDS NP_326418.1 15829058 911161 complement(705905..706783) 1 NC_002771.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 706783 rplD 911161 rplD Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L4 NP_326418.1 705905 R 272635 CDS NP_326419.1 15829059 911160 706505..707455 1 NC_002771.1 no similarity found; hypothetical protein 707455 911160 MYPU_5880 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326419.1 706505 D 272635 CDS NP_326420.1 15829060 911159 complement(706786..707586) 1 NC_002771.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 707586 rplC 911159 rplC Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L3 NP_326420.1 706786 R 272635 CDS NP_326421.1 15829061 911164 complement(707705..708016) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:O50185 (RS10_MYCHY) Blastp2 P=2e-23 C=70%; 30S ribosomal protein S10 708016 911164 MYPU_5900 Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S10 NP_326421.1 707705 R 272635 CDS NP_326422.1 15829062 911157 complement(708370..709257) 1 NC_002771.1 no similarity found Pfscan: pos. 197-239 PS00041 | HTH_ARAC_FAMILY_1 Bacterial regulatory proteins, araC family signature; hypothetical protein 709257 911157 MYPU_5910 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326422.1 708370 R 272635 CDS NP_326423.1 15829063 911162 complement(710142..710339) 1 NC_002771.1 no similarity found; hypothetical protein 710339 911162 MYPU_5920 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326423.1 710142 R 272635 CDS NP_326424.1 15829064 911163 710358..711413 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:P75290 Blastp2 P=2e-63 Id=82%; hypothetical protein 711413 911163 MYPU_5930 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326424.1 710358 D 272635 CDS NP_326425.1 15829065 911158 711460..713244 1 NC_002771.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 713244 ulaA 911158 ulaA Mycoplasma pulmonis UAB CTIP PTS system ascorbate-specific transporter subunit IIC NP_326425.1 711460 D 272635 CDS NP_326426.1 15829066 911153 713287..713577 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P39302 (PTXB_ECOLI) Blastp2 P=2e-11 C=51%; pentitol phosphotransferase enzyme II, B component 713577 911153 MYPU_5950 Mycoplasma pulmonis UAB CTIP pentitol phosphotransferase enzyme II, B component NP_326426.1 713287 D 272635 CDS NP_326427.1 15829067 911154 713577..714056 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75292 (PTXA_MYCPN) Blastp2 P=3e-34 C=67% Pfscan: pos. 28-91 PF00359 | PTS_EIIA_2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; pentitol phosphotransferase enzyme II, A component 714056 911154 MYPU_5960 Mycoplasma pulmonis UAB CTIP pentitol phosphotransferase enzyme II, A component NP_326427.1 713577 D 272635 CDS NP_326428.2 161723291 911152 714070..714729 1 NC_002771.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 714729 ulaD 911152 ulaD Mycoplasma pulmonis UAB CTIP 3-keto-L-gulonate-6-phosphate decarboxylase NP_326428.2 714070 D 272635 CDS NP_326429.1 15829069 911156 714665..715582 1 NC_002771.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 715582 911156 MYPU_5980 Mycoplasma pulmonis UAB CTIP L-xylulose 5-phosphate 3-epimerase NP_326429.1 714665 D 272635 CDS NP_326430.1 15829070 911148 715575..716306 1 NC_002771.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 716306 araD 911148 araD Mycoplasma pulmonis UAB CTIP L-ribulose-5-phosphate 4-epimerase NP_326430.1 715575 D 272635 CDS NP_326431.1 15829071 911155 complement(716853..717254) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P44734 (RBSD_HAEIN) Blastp2 P=2e-12 C=54%; high affinity ribose transport protein RBSD 717254 911155 MYPU_6000 Mycoplasma pulmonis UAB CTIP high affinity ribose transport protein RBSD NP_326431.1 716853 R 272635 CDS NP_326432.1 15829072 911150 complement(717305..718285) 1 NC_002771.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 718285 pfkA 911150 pfkA Mycoplasma pulmonis UAB CTIP 6-phosphofructokinase NP_326432.1 717305 R 272635 CDS NP_326433.1 15829073 911151 complement(718305..720014) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P45617 (PT1_MYCCA) Blastp2 P=0 C=71% Pfscan: pos. 153-504 PF00391 | PEP_UTILIZERS PEP-utilizing enzymes (PDOC00527) pos. 155-211 GC0258 | PEP_ENZYMES_PHOS_SITE PEP-utilizing enzymes phosphorylation site signa pos. 180-191 PS00370 | PEP_ENZYMES_PHOS_SITE PEP-utilizing enzymes phosphorylation site signature pos. 447-465 PS00742 | PEP_ENZYMES_2 PEP-utilizing enzymes signature 2; phosphoenolpyruvate-protein phosphotransferase (phosphotransferase system, enzyme I) 720014 911151 MYPU_6020 Mycoplasma pulmonis UAB CTIP phosphoenolpyruvate-protein phosphotransferase (phosphotransferase system, enzyme I) NP_326433.1 718305 R 272635 CDS NP_326434.1 15829074 911145 complement(720083..720346) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P45611 (PTHP_MYCCA) Blastp2 P=1e-22 C=73%; phosphocarrier protein HPr (histidine-containing protein) 720346 911145 MYPU_6030 Mycoplasma pulmonis UAB CTIP phosphocarrier protein HPr (histidine-containing protein) NP_326434.1 720083 R 272635 CDS NP_326435.1 15829075 911142 complement(720450..721931) 1 NC_002771.1 no similarity found Pfscan:pos. 21-31 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attacment site; lipoprotein 721931 911142 MYPU_6040 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326435.1 720450 R 272635 CDS NP_326436.1 15829076 911143 complement(722010..722513) 1 NC_002771.1 no similarity found Pfscan: pos. 11-21 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 722513 911143 MYPU_6050 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326436.1 722010 R 272635 CDS NP_326437.1 15829077 911141 complement(722494..724416) 1 NC_002771.1 no similarity found Pfscan: pos. 10-20 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 724416 911141 MYPU_6060 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326437.1 722494 R 272635 CDS NP_326438.1 15829078 911146 complement(724455..726824) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q49551 Blastp2 P=1e-08 C=31% Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site pos. 294-301 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); lipoprotein 726824 911146 MYPU_6070 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326438.1 724455 R 272635 CDS NP_326439.1 15829079 911147 complement(726817..727926) 1 NC_002771.1 no similarity found; hypothetical protein 727926 911147 MYPU_6080 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326439.1 726817 R 272635 CDS NP_326440.1 15829080 911140 complement(728041..728358) 1 NC_002771.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 728358 rpsR 911140 rpsR Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S18 NP_326440.1 728041 R 272635 CDS NP_326441.1 15829081 911144 complement(728372..728917) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q60056 (Q60056) Blastp2 P=4e-13 C=41%; single-strand binding protein (SSB) (helix-destabilizing protein) 728917 911144 MYPU_6100 Mycoplasma pulmonis UAB CTIP single-strand binding protein (SSB) (helix-destabilizing protein) NP_326441.1 728372 R 272635 CDS NP_326442.1 15829082 911138 complement(728927..729379) 1 NC_002771.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 729379 rpsF 911138 rpsF Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S6 NP_326442.1 728927 R 272635 CDS NP_326443.1 15829083 911135 complement(729513..729980) 1 NC_002771.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 729980 911135 MYPU_6120 Mycoplasma pulmonis UAB CTIP ribose-5-phosphate isomerase B NP_326443.1 729513 R 272635 CDS NP_326444.1 15829084 911149 complement(730009..730473) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O84139 (O84139) Blastp2 P=6e-10 C=46% Pfscan: pos. 1-154 PF01300 | SUA5_YCIO_YRDC SUA5/yciO/yrdC family (PDOC00883); hypothetical protein 730473 911149 MYPU_6130 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326444.1 730009 R 272635 CDS NP_326445.1 15829085 911134 730536..730826 1 NC_002771.1 no similarity found; hypothetical protein 730826 911134 MYPU_6140 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326445.1 730536 D 272635 CDS NP_326446.1 15829086 911137 730819..731484 1 NC_002771.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 731484 911137 MYPU_6150 Mycoplasma pulmonis UAB CTIP uracil-DNA glycosylase NP_326446.1 730819 D 272635 CDS NP_326447.1 15829087 911133 complement(731618..732124) 1 NC_002771.1 no similarity found; hypothetical protein 732124 911133 MYPU_6160 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326447.1 731618 R 272635 CDS NP_326448.1 15829088 911130 complement(732443..733381) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9WXW0 Blastp2 P=8e-29 score=127 Pfscan: pos. 1-236 PS50281 | BPD_TRANSP_INN_MEMB_2 Binding-system dependent bacterial transporters (araH, livH/lim) pos. 15-290 PF01032 | FECCD_FAMILY FecCD transport family (PDOC00364); sugar ABC transporter permease 733381 911130 MYPU_6170 Mycoplasma pulmonis UAB CTIP sugar ABC transporter permease NP_326448.1 732443 R 272635 CDS NP_326449.1 15829089 911132 complement(733381..735177) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL: Blastp2 P=2e-18 score=94 Pfscan: pos. 72-282 PS50281 | BPD_TRANSP_INN_MEMB_2 Binding-system dependent bacterial transporters (araH, livH/lim pos. 50-357 PF01032 | FECCD_FAMILY FecCD transport family (PDOC00364); sugar ABC transporter permease 735177 911132 MYPU_6180 Mycoplasma pulmonis UAB CTIP sugar ABC transporter permease NP_326449.1 733381 R 272635 CDS NP_326450.1 15829090 911139 complement(735170..736729) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P47365 (MGLA_MYCGE) Blastp2 P=0 C=63% Pfscan: pos. 32-57 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 141-212 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 413-484 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 325-342 PS50079 | NLS_BP Bipartite nuclear localization signal. pos. 30-216 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 283-488 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 37-44 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 321-349 PS00061 | ADH_SHORT Short-chain dehydrogenases/reductases family signature pos. 413-427 PS00211 | ABC_TRANSPORTER ABC transporters family signature; sugar ABC transporter ATP-binding protein MGLA 736729 911139 MYPU_6190 Mycoplasma pulmonis UAB CTIP sugar ABC transporter ATP-binding protein MGLA NP_326450.1 735170 R 272635 CDS NP_326451.1 15829091 911129 complement(736820..737779) 1 NC_002771.1 no similarity found; hypothetical protein 737779 911129 MYPU_6200 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326451.1 736820 R 272635 CDS NP_326452.1 15829092 911136 complement(737792..738625) 1 NC_002771.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 738625 911136 MYPU_6210 Mycoplasma pulmonis UAB CTIP endonuclease IV NP_326452.1 737792 R 272635 CDS NP_326453.1 15829093 911131 complement(738629..739576) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9ZHJ8 (Q9ZHJ8) Blastp2 P=3e-08 C=35%; hypothetical protein 739576 911131 MYPU_6220 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326453.1 738629 R 272635 CDS NP_326454.1 15829094 911128 739697..740470 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47623 (NADE_MYCGE) Blastp2 P=3e-38 C=55%; NH(3)-dependent NAD(+) synthetase 740470 911128 MYPU_6230 Mycoplasma pulmonis UAB CTIP NH(3)-dependent NAD(+) synthetase NP_326454.1 739697 D 272635 CDS NP_326455.1 15829095 911123 740474..741199 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:O83487 (Y474_TREPA) Blastp2 P=8e-56 C=65%; hypothetical protein 741199 911123 MYPU_6240 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326455.1 740474 D 272635 CDS NP_326456.1 15829096 911124 complement(742065..744317) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q58206 (Y796_METJA) Blastp2 P=4e-27 C=17% Pfscan: pos. 29-54 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 134-204 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 27-208 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 112-165 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 34-41 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 134-148 PS00211 | ABC_TRANSPORTER ABC transporters family signature TMpred prediction: 4 transmembrane helices; ABC transporter permease/ATP-binding protein 744317 911124 MYPU_6250 Mycoplasma pulmonis UAB CTIP ABC transporter permease/ATP-binding protein NP_326456.1 742065 R 272635 CDS NP_326457.1 15829097 911125 complement(744326..746248) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q58206 (Y796_METJA) Blastp2 P=4e-19 C=17% Pfscan: pos. 31-52 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 135-205 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 29-209 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 113-166 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 36-43 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 135-149 PS00211 | ABC_TRANSPORTER ABC transporters family signature Tmpred prediction: 4 transmembrane helices; ABC transporter permease/ATP-binding protein 746248 911125 MYPU_6260 Mycoplasma pulmonis UAB CTIP ABC transporter permease/ATP-binding protein NP_326457.1 744326 R 272635 CDS NP_326458.1 15829098 911122 complement(746229..747269) 1 NC_002771.1 no similarity found; hypothetical protein 747269 911122 MYPU_6270 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326458.1 746229 R 272635 CDS NP_326459.1 15829099 911120 complement(747278..747991) 1 NC_002771.1 no similarity found; hypothetical protein 747991 911120 MYPU_6280 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326459.1 747278 R 272635 CDS NP_326460.1 15829100 911119 complement(747982..748125) 1 NC_002771.1 no similarity found; hypothetical protein 748125 911119 MYPU_6290 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326460.1 747982 R 272635 CDS NP_326461.1 15829101 911117 complement(748816..749271) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P41027 (LEPC_BACCL) Blastp2 P=7e-14 C=45%; Signal peptidase I (SPase I) (leader peptidase I) 749271 911117 MYPU_6300 Mycoplasma pulmonis UAB CTIP Signal peptidase I (SPase I) (leader peptidase I) NP_326461.1 748816 R 272635 CDS NP_326462.1 15829102 911115 complement(749385..749540) 1 NC_002771.1 no similarity found; hypothetical protein 749540 911115 MYPU_6310 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326462.1 749385 R 272635 CDS NP_326463.1 15829103 911118 complement(749674..751497) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P14899 (AMY3_DICTH) Blastp2 P=3e-46 C=37% Pfscan: 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; 1,4-alpha-D-glucan glucanohydrolase 751497 911118 MYPU_6320 Mycoplasma pulmonis UAB CTIP 1,4-alpha-D-glucan glucanohydrolase NP_326463.1 749674 R 272635 CDS NP_326464.1 15829104 911114 752092..753726 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P29094 (O16G_BACTR) Blastp2 P=3e-95 C=58%; oligo-1,6-glucosidase 753726 911114 MYPU_6330 Mycoplasma pulmonis UAB CTIP oligo-1,6-glucosidase NP_326464.1 752092 D 272635 CDS NP_326465.1 15829105 911121 753730..756063 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P77154 (YCJT_ECOLI) Blastp2 P=3e-95 C=48%; hypothetical protein 756063 911121 MYPU_6340 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326465.1 753730 D 272635 CDS NP_326466.1 15829106 911113 756038..756715 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O06995 (PGMB_BACSU) Blastp2 P=3e-37 C=58%; BETA-phosphoglucomutase (BETA-PGM) 756715 911113 MYPU_6350 Mycoplasma pulmonis UAB CTIP BETA-phosphoglucomutase (BETA-PGM) NP_326466.1 756038 D 272635 CDS NP_326467.1 15829107 911112 756916..757317 1 NC_002771.1 no similarity found; hypothetical protein 757317 911112 MYPU_6360 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326467.1 756916 D 272635 CDS NP_326468.1 15829108 911116 757326..759656 1 NC_002771.1 no similarity found Pfscan: pos. 13-23 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 759656 911116 MYPU_6370 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326468.1 757326 D 272635 CDS NP_326469.1 15829109 911110 759665..760129 1 NC_002771.1 no similarity found; hypothetical protein 760129 911110 MYPU_6380 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326469.1 759665 D 272635 CDS NP_326470.1 15829110 911108 760147..763251 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q04698 (MALC_STRPN) Blastp2 P=7e-47 C=19% Pfscan: pos. 908-990 PF00528 | BPD_TRANSP Binding-protein-dependent transport systems inner membrane component pos. 899-957 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inne pos. 909-937 PS00402 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inner membrane comp. sign; maltodextrin ABC transporter permease 763251 911108 MYPU_6390 Mycoplasma pulmonis UAB CTIP maltodextrin ABC transporter permease NP_326470.1 760147 D 272635 CDS NP_326471.1 15829111 911111 763251..764195 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q04699 (MALD_STRPN) Blastp2 P=2e-40 C=45% Pfscan: pos. 196-270 PF00528 | BPD_TRANSP Binding-protein-dependent transport systems inner membrane component pos. 186-245 GC0426 | BPD_TRANSP_INN_MEMBR Binding-protein-dependent transport systems inne; maltodextrin ABC transporter permease 764195 911111 MYPU_6400 Mycoplasma pulmonis UAB CTIP maltodextrin ABC transporter permease NP_326471.1 763251 D 272635 CDS NP_326472.1 15829112 911109 764197..765375 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P94360 (MSMX_BACSU) Blastp2 P=3e-82 C=60% Pfscan: pos. 64-85 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 167-239 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 62-243 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 145-198 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 69-76 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 167-181 PS00211 | ABC_TRANSPORTER ABC transporters family signature; maltodextrin ABC transporter ATP-binding protein 765375 911109 MYPU_6410 Mycoplasma pulmonis UAB CTIP maltodextrin ABC transporter ATP-binding protein NP_326472.1 764197 D 272635 CDS NP_326473.1 15829113 911106 765375..765929 1 NC_002771.1 no similarity found; hypothetical protein 765929 911106 MYPU_6420 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326473.1 765375 D 272635 CDS NP_326474.1 15829114 911107 complement(766244..766813) 1 NC_002771.1 no similarity found Pfscan: pos. 2-41 PF00392 | GNTR Bacterial regulatory proteins, gntR family (PDOC00042); hypothetical protein 766813 911107 MYPU_6430 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326474.1 766244 R 272635 CDS NP_326475.1 15829115 911103 complement(767057..769132) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:O33840 (PULA_THEMA) Blastp2 P=8e-41 C=36%; alpha-dextrin endo-1,6-alpha-glucosidase 769132 911103 MYPU_6440 Mycoplasma pulmonis UAB CTIP alpha-dextrin endo-1,6-alpha-glucosidase NP_326475.1 767057 R 272635 CDS NP_326476.1 15829116 911126 769444..770142 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P47295 (DEOD_MYCGE) Blastp2 P=3e-47 C=63%; purine nucleoside phosphorylase 770142 911126 MYPU_6450 Mycoplasma pulmonis UAB CTIP purine nucleoside phosphorylase NP_326476.1 769444 D 272635 CDS NP_326477.1 15829117 911100 770151..771443 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P77836 (PDP_BACST) Blastp2 P=0 C=68%; thymidine phosphorylase 771443 911100 MYPU_6460 Mycoplasma pulmonis UAB CTIP thymidine phosphorylase NP_326477.1 770151 D 272635 CDS NP_326478.1 15829118 911127 771590..774220 1 NC_002771.1 no similarity found TMpred: 1 transmembrane helice; hypothetical protein 774220 911127 MYPU_6470 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326478.1 771590 D 272635 CDS NP_326479.1 15829119 911099 774327..775178 1 NC_002771.1 no similarity found; hypothetical protein 775178 911099 MYPU_6480 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326479.1 774327 D 272635 CDS NP_326480.1 15829120 911102 775472..775939 1 NC_002771.1 no similarity found; hypothetical protein 775939 911102 MYPU_6490 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326480.1 775472 D 272635 CDS NP_326481.1 15829121 911101 776884..780552 1 NC_002771.1 no similarity found TMpred prediction: 1 transmembrane helice; hypothetical protein 780552 911101 MYPU_6500 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326481.1 776884 D 272635 CDS NP_326482.1 15829122 911098 780922..784740 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9YVT6 (Q9YVT6) Blastp2 P=3e-06 C=22% TMpred: 1 transmembrane helice; hypothetical protein 784740 911098 MYPU_6510 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326482.1 780922 D 272635 CDS NP_326483.1 15829123 911097 complement(784939..785568) 1 NC_002771.1 no similarity found Pfscan: pos. 14-24 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 785568 911097 MYPU_6520 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326483.1 784939 R 272635 CDS NP_326484.1 15829124 911104 complement(785579..785968) 1 NC_002771.1 no similarity found; hypothetical protein 785968 911104 MYPU_6530 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326484.1 785579 R 272635 CDS NP_326485.1 15829125 911091 complement(786464..787096) 1 NC_002771.1 no similarity found Pfscan: pos. 14-24 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment; lipoprotein 787096 911091 MYPU_6540 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326485.1 786464 R 272635 CDS NP_326486.1 15829126 911096 complement(787107..788768) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P00780 (SUBT_BACLI) Blastp2 P=6e-11 C=18% Pfscan: pos. 355-376 PF00082 | SUBTILASE Subtilase (PDOC00125) pos. 339-389 GC0305 | SUBTILASE_SER Serine proteases, subtilase, serine activ pos. 339-346 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 358-368 PS00138 | SUBTILASE_SER Serine proteases, subtilase, serine active site; subtilisin: serine protease 788768 911096 MYPU_6550 Mycoplasma pulmonis UAB CTIP subtilisin: serine protease NP_326486.1 787107 R 272635 CDS NP_326487.2 161723290 911105 complement(788923..789192) 1 NC_002771.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 789192 rpsT 911105 rpsT Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S20 NP_326487.2 788923 R 272635 CDS NP_326488.1 15829128 911095 789431..790024 1 NC_002771.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 790024 ruvA 911095 ruvA Mycoplasma pulmonis UAB CTIP Holliday junction DNA helicase RuvA NP_326488.1 789431 D 272635 CDS NP_326489.1 15829129 911092 790002..790949 1 NC_002771.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 790949 ruvB 911092 ruvB Mycoplasma pulmonis UAB CTIP Holliday junction DNA helicase RuvB NP_326489.1 790002 D 272635 CDS NP_326490.1 15829130 911094 complement(790985..793606) 1 NC_002771.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 793606 911094 MYPU_6590 Mycoplasma pulmonis UAB CTIP bifunctional preprotein translocase subunit SecD/SecF NP_326490.1 790985 R 272635 CDS NP_326491.1 15829131 911088 complement(793723..794184) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q54723 (Q54723) Blastp2 P=1e-12 C=49%; hypothetical protein 794184 911088 MYPU_6600 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326491.1 793723 R 272635 CDS NP_326492.1 15829132 911085 complement(794294..795820) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:O34739 Blastp2 P=3e-9 C=24% Pfscan: pos. 2-257 PS50285 | AMINO_ACID_PERMEASE_2 Permeases for amino acids and related compounds, family I. pos. 18-451 PF00324 | AA_PERMEASES Amino acid permease (PDOC00191); amino acid permease 795820 911085 MYPU_6610 Mycoplasma pulmonis UAB CTIP amino acid permease NP_326492.1 794294 R 272635 CDS NP_326493.1 15829133 911083 795971..796675 1 NC_002771.1 no similarity found; hypothetical protein 796675 911083 MYPU_6620 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326493.1 795971 D 272635 CDS NP_326494.1 15829134 911090 796700..798367 1 NC_002771.1 no similarity found; Pfscan: pos. 421-481 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 21-497 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 28-35 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 798367 911090 MYPU_6630 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326494.1 796700 D 272635 CDS NP_326495.1 15829135 911082 798354..798653 1 NC_002771.1 no similarity found; hypothetical protein 798653 911082 MYPU_6640 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326495.1 798354 D 272635 CDS NP_326496.1 15829136 911086 798844..800349 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P31071 (CLS_ECOLI) Blastp2 P=3e-29 C=37% Pfscan: pos. 241-268 PS50035 | PLD_DOMAIN Phospholipase D/Transphosphatidylase pos. 241-268 PF00614 | PLDC Phospholipase D. Active site motif; cardiolipin synthetase 800349 911086 MYPU_6650 Mycoplasma pulmonis UAB CTIP cardiolipin synthetase NP_326496.1 798844 D 272635 CDS NP_326497.1 15829137 911079 800910..802529 1 NC_002771.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 802529 pyrG 911079 pyrG Mycoplasma pulmonis UAB CTIP CTP synthetase NP_326497.1 800910 D 272635 CDS NP_326498.1 15829138 911089 802541..805207 1 NC_002771.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 805207 ileS 911089 ileS Mycoplasma pulmonis UAB CTIP isoleucyl-tRNA synthetase NP_326498.1 802541 D 272635 CDS NP_326499.1 15829139 911084 805123..805953 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9X7E7 Blast2p P=4e-9 score=62 Pfscan: pos. 58-211 PF01252 | SPASE_II Signal peptidase (SPase) II (PDOC00669); lipoprotein signal peptidase 805953 911084 MYPU_6680 Mycoplasma pulmonis UAB CTIP lipoprotein signal peptidase NP_326499.1 805123 D 272635 CDS NP_326500.1 15829140 911078 complement(806039..808021) 1 NC_002771.1 no similarity found; hypothetical protein 808021 911078 MYPU_6690 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326500.1 806039 R 272635 CDS NP_326501.1 15829141 911087 complement(808164..810107) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q9YVT6 (Q9YVT6) Blastp2 P=6e-13 C=38%; hypothetical protein 810107 911087 MYPU_6700 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326501.1 808164 R 272635 CDS NP_326502.1 15829142 911072 complement(815483..816295) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47488 (Y246_MYCGE) Blastp2 P=2e-52 C=58%; hypothetical protein 816295 911072 MYPU_6710 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326502.1 815483 R 272635 CDS NP_326503.1 15829143 911074 complement(816334..816672) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:O34272 (RBFA_YEREN) Blastp2 P=8e-07 C=45%; ribosome-binding factor A 816672 911074 MYPU_6720 Mycoplasma pulmonis UAB CTIP ribosome-binding factor A NP_326503.1 816334 R 272635 CDS NP_326504.1 15829144 911073 complement(816747..816986) 1 NC_002771.1 identified by sequence similarity; probable; similar to TREMBL:O05290 (O05290) Blastp2 P=2e-12 C=67%; hypothetical protein 816986 911073 MYPU_6730 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326504.1 816747 R 272635 CDS NP_326505.1 15829145 911076 complement(816964..818085) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:O32861 (FTSY_MYCHO) Blastp2 P=0 C=62%; cell division protein FTSY 818085 911076 MYPU_6740 Mycoplasma pulmonis UAB CTIP cell division protein FTSY NP_326505.1 816964 R 272635 CDS NP_326506.1 15829146 911075 818449..822756 1 NC_002771.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 822756 polC 911075 polC Mycoplasma pulmonis UAB CTIP DNA polymerase III PolC NP_326506.1 818449 D 272635 CDS NP_326507.1 15829147 911067 822805..823911 1 NC_002771.1 identified by sequence similarity; similar to TREMBL: Q50356 Blastp2 P=0.0 Id=87% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction modification enzyme subunit S1A 823911 911067 MYPU_6760 Mycoplasma pulmonis UAB CTIP restriction modification enzyme subunit S1A NP_326507.1 822805 D 272635 CDS NP_326508.1 15829148 911069 823904..826864 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50357 Blastp2 P=0.0 Id=95% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit R1 826864 911069 MYPU_6770 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit R1 NP_326508.1 823904 D 272635 CDS NP_326509.1 15829149 911066 826868..828430 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q505358 Blastp2 P=0.0 Id=97% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit M1 828430 911066 MYPU_6780 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit M1 NP_326509.1 826868 D 272635 CDS NP_326510.1 15829150 911064 complement(828475..829584) 1 NC_002771.1 identified by sequence similarity; probable; similar to TREMBL:Q50359 Blastp2 P=0 C=95% ; Dybvig K., Sitaraman R., French C.T., A family of phase-variable restriction enzymes with differing specificities generated by high-frequency gene rearrangements, Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13923-8 ; Sitaraman R., Dybvig K., The hsd loci of Mycoplasma pulmonis: organization, rearrangements and expression of genes, Mol Microbiol. 1997 Oct;26(1):109-20.; restriction-modification enzyme subunit S1B 829584 911064 MYPU_6790 Mycoplasma pulmonis UAB CTIP restriction-modification enzyme subunit S1B NP_326510.1 828475 R 272635 CDS NP_326511.1 15829151 911065 830019..830171 1 NC_002771.1 no similarity found; hypothetical protein 830171 911065 MYPU_6800 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326511.1 830019 D 272635 CDS NP_326512.1 15829152 911063 complement(830846..831226) 1 NC_002771.1 identified by sequence similarity; probable; similar to TREMBL:Q50355 (Q50355) Blastp2 P=2e-66 C=100% ; Dybvig K., Yu H.; Regulation of a restriction and modification system via DNA inversion in Mycoplasma pulmonis.; Mol. Microbiol. 12:547-560(1994); glutamyl-tRNA synthetase 831226 911063 MYPU_6810 Mycoplasma pulmonis UAB CTIP glutamyl-tRNA synthetase NP_326512.1 830846 R 272635 CDS NP_326513.1 15829153 911061 complement(831217..832623) 1 NC_002771.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 832623 gltX 911061 gltX Mycoplasma pulmonis UAB CTIP glutamyl-tRNA synthetase NP_326513.1 831217 R 272635 CDS NP_326514.1 15829154 911059 complement(832656..833303) 1 NC_002771.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 833303 911059 MYPU_6830 Mycoplasma pulmonis UAB CTIP ribulose-phosphate 3-epimerase NP_326514.1 832656 R 272635 CDS NP_326515.1 15829155 911057 complement(833303..834121) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47356 (Y110_MYCGE) Blastp2 P=1e-27 C=46% Pfscan: pos. 151-158 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 834121 911057 MYPU_6840 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326515.1 833303 R 272635 CDS NP_326516.1 15829156 911093 complement(834125..835087) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P54744 (PKNB_MYCLE) Blastp2 P=1e-29 C=41%; serine/threonine-protein kinase PKNB 835087 911093 MYPU_6850 Mycoplasma pulmonis UAB CTIP serine/threonine-protein kinase PKNB NP_326516.1 834125 R 272635 CDS NP_326517.1 15829157 911062 complement(835109..835846) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47354 (PPH_MYCGE) Blastp2 P=6e-23 C=53%; protein phosphatase 835846 911062 MYPU_6860 Mycoplasma pulmonis UAB CTIP protein phosphatase NP_326517.1 835109 R 272635 CDS NP_326518.1 15829158 911060 complement(835858..836448) 1 NC_002771.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 836448 gmk 911060 gmk Mycoplasma pulmonis UAB CTIP guanylate kinase NP_326518.1 835858 R 272635 CDS NP_326519.1 15829159 911058 complement(836497..837045) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P44869 (YHHF_HAEIN) Blastp2 P=2e-17 C=50% Pfscan: pos. 46-151 PS50193 | SAM_BIND SAM (and some other nucleotide) binding motif. pos. 93-143 GC0202 | N6_MTASE N-6 Adenine-specific DNA methylases signature. pos. 115-121 PS00092 | N6_MTASE N-6 Adenine-specific DNA methylases signature; DNA methylase 837045 911058 MYPU_6880 Mycoplasma pulmonis UAB CTIP DNA methylase NP_326519.1 836497 R 272635 CDS NP_326520.1 15829160 911068 837104..837700 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q45495 (DEF2_BACSU) Blastp2 P=8e-21 C=49%; polypeptide deformylase 837700 911068 MYPU_6890 Mycoplasma pulmonis UAB CTIP polypeptide deformylase NP_326520.1 837104 D 272635 CDS NP_326521.1 15829161 911056 complement(837803..839416) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75790 (YBIT_ECOLI) Blastp2 P=0 C=63% Pfscan: pos. 29-54 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 156-224 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 447-515 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 27-228 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 346-519 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 425-478 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 34-41 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); ABC transporter ATP-binding protein 839416 911056 MYPU_6900 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_326521.1 837803 R 272635 CDS NP_326522.1 15829162 911054 complement(839520..840563) 1 NC_002771.1 no similarity found; hypothetical protein 840563 911054 MYPU_6910 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326522.1 839520 R 272635 CDS NP_326523.1 15829163 911053 complement(840623..841597) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75144 (MGPA_MYCPN) Blastp2 P=3e-75 C=64% ; Sperker, B. et al., 1991. Molecular Microbiology. 5:299-306. Inamine, I. et al., 1988. Gene. 73:175-183.; hypothetical protein 841597 911053 MYPU_6920 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326523.1 840623 R 272635 CDS NP_326524.1 15829164 911055 complement(841653..845030) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:Q50321 (Q50321) Blastp2 P=1e-52 C=15% Pfscan: pos. 14-24 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; membrane nuclease, lipoprotein 845030 911055 MYPU_6930 Mycoplasma pulmonis UAB CTIP membrane nuclease, lipoprotein NP_326524.1 841653 R 272635 CDS NP_326525.1 15829165 911049 complement(845083..846267) 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:Q50321 (Q50321) Blastp2 P=2e-53 C=43%; membrane nuclease 846267 911049 MYPU_6940 Mycoplasma pulmonis UAB CTIP membrane nuclease NP_326525.1 845083 R 272635 CDS NP_326526.1 15829166 911070 846769..847587 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:P75268 Blas2p P=0.11 score=38 Pfscan: pos. 24-112 PS50187 | ESTERASE Esterase/lipase/thioesterase active site serine.; esterase 847587 911070 MYPU_6950 Mycoplasma pulmonis UAB CTIP esterase NP_326526.1 846769 D 272635 CDS NP_326527.1 15829167 911051 complement(847620..847811) 1 NC_002771.1 required for 70S ribosome assembly; 50S ribosomal protein L28 847811 rpmB 911051 rpmB Mycoplasma pulmonis UAB CTIP 50S ribosomal protein L28 NP_326527.1 847620 R 272635 CDS NP_326528.1 15829168 911052 complement(848279..848440) 1 NC_002771.1 no similarity found; hypothetical protein 848440 911052 MYPU_6970 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326528.1 848279 R 272635 CDS NP_326529.1 15829169 911050 complement(848476..850680) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q53727 (PCRA_STAAU) Blastp2 P=0 C=52%; ATP-dependent helicase PcrA 850680 911050 MYPU_6980 Mycoplasma pulmonis UAB CTIP ATP-dependent helicase PcrA NP_326529.1 848476 R 272635 CDS NP_326530.1 15829170 911044 complement(850778..852184) 1 NC_002771.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 852184 911044 MYPU_6990 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit beta NP_326530.1 850778 R 272635 CDS NP_326531.1 15829171 911046 complement(852186..853715) 1 NC_002771.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 853715 911046 MYPU_7000 Mycoplasma pulmonis UAB CTIP ATP synthase F0F1 subunit alpha NP_326531.1 852186 R 272635 CDS NP_326532.1 15829172 911047 complement(853737..854381) 1 NC_002771.1 no similarity found; hypothetical protein 854381 911047 MYPU_7010 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326532.1 853737 R 272635 CDS NP_326533.1 15829173 911045 854671..855801 1 NC_002771.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 855801 911045 MYPU_7020 Mycoplasma pulmonis UAB CTIP S-adenosylmethionine synthetase NP_326533.1 854671 D 272635 CDS NP_326534.1 15829174 911039 complement(855865..858123) 1 NC_002771.1 no similarity found; hypothetical protein 858123 911039 MYPU_7030 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326534.1 855865 R 272635 CDS NP_326535.1 15829175 911042 complement(858252..860147) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q45493 (YKQC_BACSU) Blastp2 P=0 C=50% Pfscan: pos. 6-210 PF00753 | LACTAMASE_B Metallo-beta-lactamase superfamily pos. 11-18 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 28-39 PS00136 | SUBTILASE_ASP Serine proteases, subtilase, aspartic acid active site; hypothetical protein 860147 911042 MYPU_7040 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326535.1 858252 R 272635 CDS NP_326536.1 15829176 911041 860431..862071 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47662 (Y423_MYCGE) Blastp2 P=2e-59 C=50%; hypothetical protein 862071 911041 MYPU_7050 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326536.1 860431 D 272635 CDS NP_326537.1 15829177 911038 862074..863111 1 NC_002771.1 no similarity found; hypothetical protein 863111 911038 MYPU_7060 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326537.1 862074 D 272635 CDS NP_326538.1 15829178 911037 863111..863440 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P14949 (THIO_BACSU) Blastp2 P=4e-07 C=46% Pfscan: pos. 1-109 PS50223 | THIOREDOXIN_2 Thioredoxin-domain pos. 20-60 PF00085 | THIORED Thioredoxin (PDOC00172); thioredoxin 863440 911037 MYPU_7070 Mycoplasma pulmonis UAB CTIP thioredoxin NP_326538.1 863111 D 272635 CDS NP_326539.1 15829179 911043 complement(863641..864138) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P80864 (TPX_BACSU) Blastp2 P=5e-26 C=55%; thiol peroxidase 864138 911043 MYPU_7080 Mycoplasma pulmonis UAB CTIP thiol peroxidase NP_326539.1 863641 R 272635 CDS NP_326540.1 15829180 911040 complement(864141..865676) 1 NC_002771.1 no similarity found; hypothetical protein 865676 911040 MYPU_7090 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326540.1 864141 R 272635 CDS NP_326541.1 15829181 911036 865940..868774 1 NC_002771.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 868774 uvrA 911036 uvrA Mycoplasma pulmonis UAB CTIP excinuclease ABC subunit A NP_326541.1 865940 D 272635 CDS NP_326542.1 15829182 911033 868774..869703 1 NC_002771.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 869703 911033 MYPU_7110 Mycoplasma pulmonis UAB CTIP HPr kinase/phosphorylase NP_326542.1 868774 D 272635 CDS NP_326543.1 15829183 911035 869693..870661 1 NC_002771.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 870661 911035 MYPU_7120 Mycoplasma pulmonis UAB CTIP prolipoprotein diacylglyceryl transferase NP_326543.1 869693 D 272635 CDS NP_326544.1 15829184 911034 870648..871571 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P80880 (TRXB_BACSU) Blastp2 P=4e-62 C=62%; thioredoxin reductase 871571 911034 MYPU_7130 Mycoplasma pulmonis UAB CTIP thioredoxin reductase NP_326544.1 870648 D 272635 CDS NP_326545.1 15829185 911029 871674..874613 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P41508 (P115_MYCHR) Blastp2 P=0 C=64% Pfscan: pos. 876-950 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 791-953 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 31-38 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 876-890 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 874613 911029 MYPU_7140 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_326545.1 871674 D 272635 CDS NP_326546.1 15829186 911031 complement(874597..874824) 1 NC_002771.1 no similarity found; hypothetical protein 874824 911031 MYPU_7150 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326546.1 874597 R 272635 CDS NP_326547.1 15829187 911032 complement(874802..875401) 1 NC_002771.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 875401 rpsD 911032 rpsD Mycoplasma pulmonis UAB CTIP 30S ribosomal protein S4 NP_326547.1 874802 R 272635 CDS NP_326548.1 15829188 911030 875626..877290 1 NC_002771.1 no similarity found; hypothetical protein 877290 911030 MYPU_7170 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326548.1 875626 D 272635 CDS NP_326549.1 15829189 911028 877293..878432 1 NC_002771.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 878432 911028 MYPU_7180 Mycoplasma pulmonis UAB CTIP thiamine biosynthesis protein ThiI NP_326549.1 877293 D 272635 CDS NP_326550.1 15829190 911026 878445..881390 1 NC_002771.1 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 881390 dnaE 911026 dnaE Mycoplasma pulmonis UAB CTIP DNA polymerase III DnaE NP_326550.1 878445 D 272635 CDS NP_326551.1 15829191 911027 881383..882276 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q59156 (DPO1_ANATH) Blastp2 P=8e-33 C=46% ; M. pulmonis polA is missing the C-terminal 3'-5' exonuclease domain (Klenow fragment); DNA polymerase I (POL I) 882276 911027 MYPU_7200 Mycoplasma pulmonis UAB CTIP DNA polymerase I (POL I) NP_326551.1 881383 D 272635 CDS NP_326552.1 15829192 911023 882270..882788 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O25502 Blastp2 P=2e-9 score=62.5 Pfscan: pos. 1-171 PF01121 | UPF0038 Uncharacterized protein family UPF0038 (PDOC00996) pos. 6-13 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); hypothetical protein 882788 911023 MYPU_7210 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326552.1 882270 D 272635 CDS NP_326553.1 15829193 911022 882869..883813 1 NC_002771.1 no similarity found; hypothetical protein 883813 911022 MYPU_7220 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326553.1 882869 D 272635 CDS NP_326554.1 15829194 911021 883823..884677 1 NC_002771.1 no similarity found; hypothetical protein 884677 911021 MYPU_7230 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326554.1 883823 D 272635 CDS NP_326555.1 15829195 911019 complement(884683..886008) 1 NC_002771.1 no similarity found; hypothetical protein 886008 911019 MYPU_7240 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326555.1 884683 R 272635 CDS NP_326556.1 15829196 911048 complement(886015..886926) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q59935 (MANA_STRMU) Blastp2 P=1e-31 C=40%; mannose-6-phosphate isomerase 886926 911048 MYPU_7250 Mycoplasma pulmonis UAB CTIP mannose-6-phosphate isomerase NP_326556.1 886015 R 272635 CDS NP_326557.1 15829197 911018 complement(887461..888825) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P47707 (AMPL_MYCSA) Blastp2 P=0 C=66% ; Pfscan: pos. 24-429 PF00883 | PEPTIDASE_M17 Cytosol aminopeptidase (PDOC00548) pos. 310-317 PS00631 | CYTOSOL_AP Cytosol aminopeptidase signature; aminopeptidase 888825 911018 MYPU_7260 Mycoplasma pulmonis UAB CTIP aminopeptidase NP_326557.1 887461 R 272635 CDS NP_326558.1 15829198 911024 complement(889065..889724) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O05216 Blast2p P=2e-4 score=46; chromate transporter 889724 911024 MYPU_7270 Mycoplasma pulmonis UAB CTIP chromate transporter NP_326558.1 889065 R 272635 CDS NP_326559.1 15829199 911016 complement(889724..890329) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O05216 (O05216) Blastp2 P=2e-11 C=26% Pfscan: pos. 73-80 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop); chromate transporter 890329 911016 MYPU_7280 Mycoplasma pulmonis UAB CTIP chromate transporter NP_326559.1 889724 R 272635 CDS NP_326560.1 15829200 911013 890366..891073 1 NC_002771.1 no similarity found; hypothetical protein 891073 911013 MYPU_7290 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326560.1 890366 D 272635 CDS NP_326561.1 15829201 911009 891060..892163 1 NC_002771.1 identified by sequence similarity; possible; similar to TREMBL:CAB49557 Blastp2 P=1e-46 score=187; aminopeptidase 892163 911009 MYPU_7300 Mycoplasma pulmonis UAB CTIP aminopeptidase NP_326561.1 891060 D 272635 CDS NP_326562.1 15829202 911025 892296..893381 1 NC_002771.1 no similarity found; hypothetical protein 893381 911025 MYPU_7310 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326562.1 892296 D 272635 CDS NP_326563.1 15829203 911010 893749..894414 1 NC_002771.1 no similarity found; hypothetical protein 894414 911010 MYPU_7320 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326563.1 893749 D 272635 CDS NP_326564.1 15829204 911007 894456..895607 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q05646 (DNAJ_ERYRH) Blastp2 P=7e-60 C=49%; molecular chaperone DnaJ 895607 911007 MYPU_7330 Mycoplasma pulmonis UAB CTIP molecular chaperone DnaJ NP_326564.1 894456 D 272635 CDS NP_326565.1 15829205 911012 complement(895721..897769) 1 NC_002771.1 identified by sequence similarity; unknown; similar to TREMBL:Q49537 Blastp2 P=2e-06 score=55 Pfscan: pos. 17-27 PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 897769 911012 MYPU_7340 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326565.1 895721 R 272635 CDS NP_326566.1 15829206 911008 complement(898013..902653) 1 NC_002771.1 no similarity found; Pfscan: pos. 17-27 bp PS00013 | PROKAR_LIPOPROTEIN Prokaryotic membrane lipoprotein lipid attachment site; lipoprotein 902653 911008 MYPU_7350 Mycoplasma pulmonis UAB CTIP lipoprotein NP_326566.1 898013 R 272635 CDS NP_326567.1 15829207 911014 complement(902950..903168) 1 NC_002771.1 no similarity found; hypothetical protein 903168 911014 MYPU_7360 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326567.1 902950 R 272635 CDS NP_326568.1 15829208 911006 complement(903141..906116) 1 NC_002771.1 no similarity found; hypothetical protein 906116 911006 MYPU_7370 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326568.1 903141 R 272635 CDS NP_326569.1 15829209 911020 complement(906180..907676) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O51530 (O51530) Blastp2 P=5e-17 C=36%:CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN; hypothetical protein 907676 911020 MYPU_7380 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326569.1 906180 R 272635 CDS NP_326570.1 15829210 911005 complement(907738..909672) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P43053 (GYRB_MYCHO) Blastp2 P=0 C=75%; DNA gyrase subunit B 909672 911005 MYPU_7390 Mycoplasma pulmonis UAB CTIP DNA gyrase subunit B NP_326570.1 907738 R 272635 CDS NP_326571.1 15829211 911004 909730..910530 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P43044 (LICA_MYCCA) Blastp2 P=3e-58 C=55%; PTS system, lichenan-specific IIA component 910530 911004 MYPU_7400 Mycoplasma pulmonis UAB CTIP PTS system, lichenan-specific IIA component NP_326571.1 909730 D 272635 CDS NP_326572.1 15829212 911017 910767..912395 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P45861 (YWJA_BACSU) Blastp2 P=9e-12 C=25% Pfscan: pos. 364-385 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 464-522 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 362-538 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 442-495 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 369-376 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) Tmpred prediction: 5 transmembrane helices; ABC transporter permease/ATP-binding protein 912395 911017 MYPU_7410 Mycoplasma pulmonis UAB CTIP ABC transporter permease/ATP-binding protein NP_326572.1 910767 D 272635 CDS NP_326573.1 15829213 911002 912373..913989 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:Q57538 (Y664_HAEIN) Blastp2 P=8e-15 C=22% Pfscan: pos. 364-383 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 459-517 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 362-535 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 437-492 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 369-376 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) TMpred: 4 transmembrane helices; ABC transporter permease/ATP-binding protein 913989 911002 MYPU_7420 Mycoplasma pulmonis UAB CTIP ABC transporter permease/ATP-binding protein NP_326573.1 912373 D 272635 CDS NP_326574.1 15829214 911015 complement(914036..915517) 1 NC_002771.1 no similarity found; hypothetical protein 915517 911015 MYPU_7430 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326574.1 914036 R 272635 CDS NP_326575.1 15829215 911001 915369..915548 1 NC_002771.1 no similarity found; hypothetical protein 915548 911001 MYPU_7440 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326575.1 915369 D 272635 CDS NP_326576.1 15829216 911011 915593..916591 1 NC_002771.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 916591 911011 MYPU_7450 Mycoplasma pulmonis UAB CTIP tryptophanyl-tRNA synthetase NP_326576.1 915593 D 272635 CDS NP_326577.1 15829217 911000 916591..918360 1 NC_002771.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 918360 thrS 911000 thrS Mycoplasma pulmonis UAB CTIP threonyl-tRNA synthetase NP_326577.1 916591 D 272635 CDS NP_326578.1 15829218 910998 918364..918768 1 NC_002771.1 no similarity found; hypothetical protein 918768 910998 MYPU_7470 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326578.1 918364 D 272635 CDS NP_326579.1 15829219 910997 919068..920495 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:P75041 Blastp2 P=3e-12 score=74 Pfscan: pos. 11-467 PF00083 | SUGAR_TR Sugar (and other) transporter (PDOC00190); hexosephosphate transport protein 920495 910997 MYPU_7480 Mycoplasma pulmonis UAB CTIP hexosephosphate transport protein NP_326579.1 919068 D 272635 CDS NP_326580.1 15829220 910999 920817..921062 1 NC_002771.1 no similarity found; hypothetical protein 921062 910999 MYPU_7490 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326580.1 920817 D 272635 CDS NP_326581.1 15829221 910995 complement(921356..922438) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P78008 (MTLD_MYCPN) Blastp2 P=2e-65 C=61%; mannitol-1-phosphate 5-dehydrogenase 922438 910995 MYPU_7500 Mycoplasma pulmonis UAB CTIP mannitol-1-phosphate 5-dehydrogenase NP_326581.1 921356 R 272635 CDS NP_326582.1 15829222 910996 complement(922425..923453) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P50852 (PTMB_BACST) Blastp2 P=3e-49 C=50%; PTS system, mannitol-specific IIABC component (EIIABC-MTL) (mannitol-permease IIABC component) (phosphotransferase enzyme II, BC component) (EII-MTL) 923453 910996 MYPU_7510 Mycoplasma pulmonis UAB CTIP PTS system, mannitol-specific IIABC component (EIIABC-MTL) (mannitol-permease IIABC component) (phosphotransferase enzyme II, BC component) (EII-MTL) NP_326582.1 922425 R 272635 CDS NP_326583.1 15829223 910993 complement(923490..923876) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P42956 (PTMA_BACSU) Blastp2 P=9e-28 C=57%; PTS system, mannitol-specific IIABC component (EIIABC-MTL) (phosphotransferase enzyme II, ABC component) (EII-MTL) 923876 910993 MYPU_7520 Mycoplasma pulmonis UAB CTIP PTS system, mannitol-specific IIABC component (EIIABC-MTL) (phosphotransferase enzyme II, ABC component) (EII-MTL) NP_326583.1 923490 R 272635 CDS NP_326584.1 15829224 910994 924132..924665 1 NC_002771.1 no similarity found Pfscan: pos. 44-177 PF01380 | SIS SIS domain; hypothetical protein 924665 910994 MYPU_7530 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326584.1 924132 D 272635 CDS NP_326585.1 15829225 910990 complement(925082..925813) 1 NC_002771.1 no similarity found; hypothetical protein 925813 910990 MYPU_7540 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326585.1 925082 R 272635 CDS NP_326586.1 15829226 910991 complement(925840..926592) 1 NC_002771.1 no similarity found; hypothetical protein 926592 910991 MYPU_7550 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326586.1 925840 R 272635 CDS NP_326587.1 15829227 910989 complement(926547..927755) 1 NC_002771.1 identified by sequence similarity; identical to GenBank: Z16416 pos. 54-1259; Bhugra,B. and Dybvig,K. ; Identification and characterization of IS1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family ; Mol. Microbiol. 7 (4), 577-584 (1993); IS1138 transposase 927755 910989 MYPU_7560 Mycoplasma pulmonis UAB CTIP IS1138 transposase NP_326587.1 926547 R 272635 CDS NP_326588.1 15829228 911003 complement(927806..928102) 1 NC_002771.1 no similarity found; hypothetical protein 928102 911003 MYPU_7570 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326588.1 927806 R 272635 CDS NP_326589.1 15829229 910986 complement(928272..928946) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P43054 (YGYB_MYCHO) Blastp2 P=2e-09 C=38%; hypothetical protein 928946 910986 MYPU_7580 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326589.1 928272 R 272635 CDS NP_326590.1 15829230 910987 complement(929141..930088) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:O52354 (LDH_MYCGA) Blastp2 P=6e-61 C=58%; L-lactate dehydrogenase 930088 910987 MYPU_7590 Mycoplasma pulmonis UAB CTIP L-lactate dehydrogenase NP_326590.1 929141 R 272635 CDS NP_326591.1 15829231 910985 930126..930275 1 NC_002771.1 no similarity found; hypothetical protein 930275 910985 MYPU_7600 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326591.1 930126 D 272635 CDS NP_326592.1 15829232 910992 complement(930281..932164) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47513 (DLDH_MYCGE) Blastp2 P=0 C=45%; dihydrolipoamide dehydrogenase (E3 component of pyruvate complex) 932164 910992 MYPU_7610 Mycoplasma pulmonis UAB CTIP dihydrolipoamide dehydrogenase (E3 component of pyruvate complex) NP_326592.1 930281 R 272635 CDS NP_326593.1 15829233 910984 complement(932167..933114) 1 NC_002771.1 unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase 933114 910984 MYPU_7620 Mycoplasma pulmonis UAB CTIP dihydrolipoamide acetyltransferase NP_326593.1 932167 R 272635 CDS NP_326594.1 15829234 910981 complement(933299..934297) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75391 (ODPB_MYCPN) Blastp2 P=0 C=74%; pyruvate dehydrogenase E1 component, beta subunit 934297 910981 MYPU_7630 Mycoplasma pulmonis UAB CTIP pyruvate dehydrogenase E1 component, beta subunit NP_326594.1 933299 R 272635 CDS NP_326595.1 15829235 910980 complement(934297..935403) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75390 (ODPA_MYCPN) Blastp2 P=3e-97 C=62%; pyruvate dehydrogenase E1 component, alpha subunit 935403 910980 MYPU_7640 Mycoplasma pulmonis UAB CTIP pyruvate dehydrogenase E1 component, alpha subunit NP_326595.1 934297 R 272635 CDS NP_326596.1 15829236 910983 935546..935704 1 NC_002771.1 no similarity found; hypothetical protein 935704 910983 MYPU_7650 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326596.1 935546 D 272635 CDS NP_326597.1 15829237 910988 complement(935682..936530) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75312 (Y326_MYCPN) Blastp2 P=1e-21 C=49%; hypothetical protein 936530 910988 MYPU_7660 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326597.1 935682 R 272635 CDS NP_326598.1 15829238 910977 complement(936582..938180) 1 NC_002771.1 no similarity found; hypothetical protein 938180 910977 MYPU_7670 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326598.1 936582 R 272635 CDS NP_326599.1 15829239 910976 complement(938203..940428) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:Q53727 (PCRA_STAAU) Blastp2 P=0 C=51%; ATP-dependent helicase PcrA 940428 910976 MYPU_7680 Mycoplasma pulmonis UAB CTIP ATP-dependent helicase PcrA NP_326599.1 938203 R 272635 CDS NP_326600.1 15829240 910975 complement(940388..941017) 1 NC_002771.1 no similarity found; hypothetical protein 941017 910975 MYPU_7690 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326600.1 940388 R 272635 CDS NP_326601.1 15829241 910974 complement(941019..942029) 1 NC_002771.1 identified by sequence similarity; similar to TREMBL:O52906 P=6e-4 score=45 Pfscan: pos. 2-105 PS50167 | GLYC_TRANS General Glycosyltransferase domain; glycosyltransferase 942029 910974 MYPU_7700 Mycoplasma pulmonis UAB CTIP glycosyltransferase NP_326601.1 941019 R 272635 CDS NP_326602.1 15829242 910978 complement(942032..943384) 1 NC_002771.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 943384 asnC 910978 asnC Mycoplasma pulmonis UAB CTIP asparaginyl-tRNA synthetase NP_326602.1 942032 R 272635 CDS NP_326603.1 15829243 910979 complement(943476..944672) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P54524 (YQIG_BACSU) Blastp2 P=6e-31 C=41%; NADH-dependent flavin oxidoreductase 944672 910979 MYPU_7720 Mycoplasma pulmonis UAB CTIP NADH-dependent flavin oxidoreductase NP_326603.1 943476 R 272635 CDS NP_326604.1 15829244 910973 complement(944941..945846) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P47311 (Y065_MYCGE) Blastp2 P=2e-53 C=50% Pfscan: pos. 99-120 PS50101 | ATP_GTP_A2 P-loop nucleotide binding motif (does not find all). pos. 206-278 PS50100 | DA_BOX 2nd half motif for nucleotide binding, associated with P-loop. pos. 97-281 PF00005 | ABC_TRAN ABC transporter (PDOC00185) pos. 185-237 GC0425 | ATP_BIND_TRANSPORT ATP-binding proteins `active transport' family s pos. 104-111 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop) pos. 206-220 PS00211 | ABC_TRANSPORTER ABC transporters family signature; ABC transporter ATP-binding protein 945846 910973 MYPU_7730 Mycoplasma pulmonis UAB CTIP ABC transporter ATP-binding protein NP_326604.1 944941 R 272635 CDS NP_326605.1 15829245 910970 complement(945846..953645) 1 NC_002771.1 identified by sequence similarity; unknown; similar to SWISS-PROT:P47310 (Y064_MYCGE) Blastp2 P=6e-45 C=18% Tmpred prediction: 12 transmembrane helices; ABC transporter permease 953645 910970 MYPU_7740 Mycoplasma pulmonis UAB CTIP ABC transporter permease NP_326605.1 945846 R 272635 CDS NP_326606.1 15829246 910972 complement(953789..955594) 1 NC_002771.1 identified by sequence similarity; probable; similar to SWISS-PROT:P75448 (YC00_MYCPN) Blastp2 P=0 C=65%; carnitine O-acetyltransferase 955594 910972 MYPU_7750 Mycoplasma pulmonis UAB CTIP carnitine O-acetyltransferase NP_326606.1 953789 R 272635 CDS NP_326607.1 15829247 910971 complement(955616..957229) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P77031 (YQCE_ECOLI) Blastp2 P=2e-20 C=31%; hypothetical protein 957229 910971 MYPU_7760 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326607.1 955616 R 272635 CDS NP_326608.1 15829248 910969 955908..956135 1 NC_002771.1 no similarity found; hypothetical protein 956135 910969 MYPU_7770 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326608.1 955908 D 272635 CDS NP_326609.1 15829249 910968 complement(957274..957807) 1 NC_002771.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 957807 910968 MYPU_7780 Mycoplasma pulmonis UAB CTIP methionine sulfoxide reductase A NP_326609.1 957274 R 272635 CDS NP_326610.1 15829250 910982 complement(958010..960187) 1 NC_002771.1 identified by sequence similarity; possible; similar to SWISS-PROT:P75120 (FTSH_MYCPN) Blastp2 P=0 C=41%; cell division protein FTSH 960187 910982 MYPU_7790 Mycoplasma pulmonis UAB CTIP cell division protein FTSH NP_326610.1 958010 R 272635 CDS NP_326611.1 15829251 910967 complement(960347..961207) 1 NC_002771.1 identified by sequence similarity; similar to SWISS-PROT:P75549 (Y084_MYCPN) Blastp2 P=5e-34 C=37%; hypothetical protein 961207 910967 MYPU_7800 Mycoplasma pulmonis UAB CTIP hypothetical protein NP_326611.1 960347 R 272635 CDS NP_326612.1 15829252 910965 complement(961211..961771) 1 NC_002771.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 961771 910965 MYPU_7810 Mycoplasma pulmonis UAB CTIP peptidyl-tRNA hydrolase NP_326612.1 961211 R 272635 CDS NP_326613.1 15829253 910966 complement(961795..963879) 1 NC_002771.1 identified by sequence similarity; unknown; similar to SWISS-PROT:P04993 (EX5A_ECOLI) Blastp2 P=9e-12 C=11%; exodeoxyribonuclease V subunit alpha 963879 910966 MYPU_7820 Mycoplasma pulmonis UAB CTIP exodeoxyribonuclease V subunit alpha NP_326613.1 961795 R 272635 CDS