-- dump date 20120504_160424 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 293614000001 SEQ_END SEQ_END NC_009881.1 1231060 1231060 DR NC_009881.1; contig end 1231060..1231060 Rickettsia akari str. Hartford YP_001492846.1 CDS A1C_00005 NC_009881.1 1 822 D COG1806 Uncharacterized protein conserved in bacteria; hypothetical protein 1..822 Rickettsia akari str. Hartford 5645715 YP_001492847.1 CDS A1C_00010 NC_009881.1 964 1383 D COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 964..1383 Rickettsia akari str. Hartford 5645496 YP_001492848.1 CDS A1C_00015 NC_009881.1 1389 2138 D COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component; O-antigen export system ATP-binding protein RfbE 1389..2138 Rickettsia akari str. Hartford 5645245 YP_001492849.1 CDS A1C_00020 NC_009881.1 2139 2915 D COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component; O-antigen export system permease protein RfbA 2139..2915 Rickettsia akari str. Hartford 5645246 YP_001492850.1 CDS A1C_00025 NC_009881.1 2912 5983 D undetermined function; putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase 2912..5983 Rickettsia akari str. Hartford 5645247 YP_001492851.1 CDS A1C_00030 NC_009881.1 6021 6737 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(6021..6737) Rickettsia akari str. Hartford 5645248 YP_001492852.1 CDS fabZ NC_009881.1 6725 6814 R (3R)-hydroxymyristoyl-ACP dehydratase complement(6725..6814) Rickettsia akari str. Hartford 5644862 YP_001492853.1 CDS A1C_00040 NC_009881.1 6801 6926 D hypothetical protein 6801..6926 Rickettsia akari str. Hartford 5644863 YP_001492854.1 CDS fabZ NC_009881.1 6824 7261 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(6824..7261) Rickettsia akari str. Hartford 5644864 YP_001492855.1 CDS lpxD NC_009881.1 7480 8520 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(7480..8520) Rickettsia akari str. Hartford 5644865 YP_001492856.1 CDS A1C_00055 NC_009881.1 8972 9427 D alpha/beta hydrolase superfamily esterase 8972..9427 Rickettsia akari str. Hartford 5644866 YP_001492857.1 CDS A1C_00060 NC_009881.1 9637 9768 R hypothetical protein complement(9637..9768) Rickettsia akari str. Hartford 5644867 YP_001492858.1 CDS A1C_00065 NC_009881.1 10272 12848 R COG0542 ATPases with chaperone activity, ATP-binding subunit; clpB protein complement(10272..12848) Rickettsia akari str. Hartford 5644868 YP_001492859.1 CDS A1C_00080 NC_009881.1 14156 14263 D hypothetical protein 14156..14263 Rickettsia akari str. Hartford 5644728 YP_001492860.1 CDS A1C_00085 NC_009881.1 14247 14372 D hypothetical protein 14247..14372 Rickettsia akari str. Hartford 5644729 YP_001492861.1 CDS A1C_00090 NC_009881.1 14481 14696 D hypothetical protein 14481..14696 Rickettsia akari str. Hartford 5644730 YP_001492862.1 CDS A1C_00095 NC_009881.1 14696 15421 D catalyzes the conversion of 3-hydroxyacyl-CoA to 3-oxyacyl-CoA; acetoacetyl-CoA reductase 14696..15421 Rickettsia akari str. Hartford 5644731 YP_001492863.1 CDS A1C_00100 NC_009881.1 15625 16116 D hypothetical protein 15625..16116 Rickettsia akari str. Hartford 5644732 YP_001492864.1 CDS A1C_00105 NC_009881.1 16130 17452 D hypothetical protein 16130..17452 Rickettsia akari str. Hartford 5644733 YP_001492865.1 CDS A1C_00110 NC_009881.1 17683 17907 D hypothetical protein 17683..17907 Rickettsia akari str. Hartford 5644734 YP_001492866.1 CDS A1C_00115 NC_009881.1 17931 18044 D COG2337 Growth inhibitor; hypothetical protein 17931..18044 Rickettsia akari str. Hartford 5644934 YP_001492867.1 CDS A1C_00120 NC_009881.1 18710 18874 R cell surface antigen-like protein Sca10 complement(18710..18874) Rickettsia akari str. Hartford 5644935 YP_001492868.1 CDS A1C_00125 NC_009881.1 18801 19340 R COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; cell surface antigen-like protein Sca10 complement(18801..19340) Rickettsia akari str. Hartford 5644936 YP_001492869.1 CDS A1C_00130 NC_009881.1 19433 19570 R cell surface antigen-like protein Sca10 complement(19433..19570) Rickettsia akari str. Hartford 5644937 YP_001492870.1 CDS A1C_00135 NC_009881.1 19767 20153 R cell surface antigen-like protein Sca10 complement(19767..20153) Rickettsia akari str. Hartford 5644938 YP_001492871.1 CDS A1C_00140 NC_009881.1 20251 20529 D hypothetical protein 20251..20529 Rickettsia akari str. Hartford 5644939 YP_001492872.1 CDS A1C_00145 NC_009881.1 20543 20659 R hypothetical protein complement(20543..20659) Rickettsia akari str. Hartford 5644940 YP_001492873.1 CDS A1C_00150 NC_009881.1 21109 21303 R cell surface antigen-like protein Sca10 complement(21109..21303) Rickettsia akari str. Hartford 5645566 YP_001492874.1 CDS A1C_00155 NC_009881.1 21471 21629 R cell surface antigen-like protein Sca10 complement(21471..21629) Rickettsia akari str. Hartford 5645567 YP_001492875.1 CDS A1C_00160 NC_009881.1 22115 22783 R COG1286 Uncharacterized membrane protein, required for colicin V production; hypothetical protein complement(22115..22783) Rickettsia akari str. Hartford 5645568 YP_001492876.1 CDS A1C_00165 NC_009881.1 23018 23587 D COG1678 Putative transcriptional regulator; hypothetical protein 23018..23587 Rickettsia akari str. Hartford 5645569 YP_001492877.1 CDS A1C_00170 NC_009881.1 23598 24173 R COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems; Sco2 protein precursor complement(23598..24173) Rickettsia akari str. Hartford 5645570 YP_001492878.1 CDS A1C_00175 NC_009881.1 24487 24720 D hypothetical protein 24487..24720 Rickettsia akari str. Hartford 5645571 YP_001492879.1 CDS A1C_00180 NC_009881.1 24707 24823 D hypothetical protein 24707..24823 Rickettsia akari str. Hartford 5645572 YP_001492880.1 CDS A1C_00185 NC_009881.1 25742 26197 D COG0457 FOG: TPR repeat; hypothetical protein 25742..26197 Rickettsia akari str. Hartford 5644671 YP_001492881.1 CDS A1C_00190 NC_009881.1 26340 26573 D hypothetical protein 26340..26573 Rickettsia akari str. Hartford 5644672 YP_001492882.1 CDS A1C_00195 NC_009881.1 26701 27369 D hypothetical protein 26701..27369 Rickettsia akari str. Hartford 5644673 YP_001492883.1 CDS A1C_00200 NC_009881.1 27564 27875 D COG1539 Dihydroneopterin aldolase; folate synthesis bifunctional protein 27564..27875 Rickettsia akari str. Hartford 5644674 YP_001492884.1 CDS A1C_00205 NC_009881.1 28224 28364 D COG0262 Dihydrofolate reductase; dihydrofolate reductase 28224..28364 Rickettsia akari str. Hartford 5644675 YP_001492885.1 CDS recF NC_009881.1 29260 30342 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 29260..30342 Rickettsia akari str. Hartford 5644676 YP_001492886.1 CDS A1C_00225 NC_009881.1 30588 32192 D COG0500 SAM-dependent methyltransferases; hypothetical protein 30588..32192 Rickettsia akari str. Hartford 5644677 YP_001492887.1 CDS A1C_00230 NC_009881.1 32199 32345 D hypothetical protein 32199..32345 Rickettsia akari str. Hartford 5645537 YP_001492888.1 CDS A1C_00235 NC_009881.1 32402 32935 R COG1329 Transcriptional regulators, similar to M. xanthus CarD; transcriptional regulator complement(32402..32935) Rickettsia akari str. Hartford 5645538 YP_001492889.1 CDS A1C_00240 NC_009881.1 33114 34052 D COG1651 Protein-disulfide isomerase; protein-disulfide isomerase 33114..34052 Rickettsia akari str. Hartford 5645539 YP_001492890.1 CDS A1C_00245 NC_009881.1 34211 34468 D COG5336 Uncharacterized protein conserved in bacteria; hypothetical protein 34211..34468 Rickettsia akari str. Hartford 5645540 YP_001492891.1 CDS A1C_00250 NC_009881.1 34465 35193 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 34465..35193 Rickettsia akari str. Hartford 5645541 YP_001492892.1 CDS A1C_00255 NC_009881.1 35388 35612 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 35388..35612 Rickettsia akari str. Hartford 5645542 YP_001492893.1 CDS A1C_00260 NC_009881.1 35630 36103 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 35630..36103 Rickettsia akari str. Hartford 5645543 YP_001492894.1 CDS A1C_00265 NC_009881.1 36103 36597 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 36103..36597 Rickettsia akari str. Hartford 5644780 YP_001492895.1 CDS A1C_00270 NC_009881.1 36698 36808 R hypothetical protein complement(36698..36808) Rickettsia akari str. Hartford 5644781 YP_001492896.1 CDS A1C_00275 NC_009881.1 37122 37631 R COG0459 Chaperonin GroEL (HSP60 family); hypothetical protein complement(37122..37631) Rickettsia akari str. Hartford 5644782 YP_001492897.1 CDS A1C_00280 NC_009881.1 38026 42537 R cell surface antigen complement(38026..42537) Rickettsia akari str. Hartford 5644784 YP_001492898.1 CDS A1C_00285 NC_009881.1 43287 43862 D COG0658 Predicted membrane metal-binding protein; ComEC/Rec2 family protein 43287..43862 Rickettsia akari str. Hartford 5644785 YP_001492899.1 CDS A1C_00290 NC_009881.1 44125 44382 D ComEC/Rec2-like protein 44125..44382 Rickettsia akari str. Hartford 5645723 YP_001492900.1 CDS A1C_00295 NC_009881.1 44786 45943 D COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Poly(A) polymerase 44786..45943 Rickettsia akari str. Hartford 5645724 YP_001492901.1 CDS A1C_00300 NC_009881.1 46006 46845 D COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; zinc/manganese ABC transporter substrate binding protein 46006..46845 Rickettsia akari str. Hartford 5645725 YP_001492902.1 CDS A1C_00305 NC_009881.1 46833 47348 D COG0802 Predicted ATPase or kinase; hypothetical protein 46833..47348 Rickettsia akari str. Hartford 5645726 YP_001492903.1 CDS A1C_00310 NC_009881.1 47353 47550 R antitoxin of toxin-antitoxin system StbD complement(47353..47550) Rickettsia akari str. Hartford 5645727 YP_001492904.1 CDS A1C_00315 NC_009881.1 47579 48535 R hypothetical protein complement(47579..48535) Rickettsia akari str. Hartford 5645728 YP_001492905.1 CDS A1C_00320 NC_009881.1 48532 49515 R COG0042 tRNA-dihydrouridine synthase; nifR3 family TIM-barrel protein complement(48532..49515) Rickettsia akari str. Hartford 5645729 YP_001492906.1 CDS A1C_00325 NC_009881.1 50123 50449 R COG1943 Transposase and inactivated derivatives; transposase IS200-family protein complement(50123..50449) Rickettsia akari str. Hartford 5645314 YP_001492907.1 CDS A1C_00330 NC_009881.1 51227 51445 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 51227..51445 Rickettsia akari str. Hartford 5645315 YP_001492908.1 CDS rpsF NC_009881.1 51835 51969 R 30S ribosomal protein S6 complement(51835..51969) Rickettsia akari str. Hartford 5645316 YP_001492909.1 CDS rpsF NC_009881.1 52263 52691 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 52263..52691 Rickettsia akari str. Hartford 5645317 YP_001492910.1 CDS rpsR NC_009881.1 52716 53003 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 52716..53003 Rickettsia akari str. Hartford 5645318 YP_001492911.1 CDS rplI NC_009881.1 53015 53530 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 53015..53530 Rickettsia akari str. Hartford 5644920 YP_001492912.1 CDS A1C_00355 NC_009881.1 53771 55063 D COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile)-lysidine synthetase TilS 53771..55063 Rickettsia akari str. Hartford 5644921 YP_001492913.1 CDS A1C_00360 NC_009881.1 55116 57029 D COG0465 ATP-dependent Zn proteases; cell division protein ftsH 55116..57029 Rickettsia akari str. Hartford 5644922 YP_001492914.1 CDS A1C_00365 NC_009881.1 57126 57407 D COG0270 Site-specific DNA methylase; site-specific DNA methylase 57126..57407 Rickettsia akari str. Hartford 5644923 YP_001492915.1 CDS sdhB NC_009881.1 57985 58125 D succinate dehydrogenase iron-sulfur subunit 57985..58125 Rickettsia akari str. Hartford 5644924 YP_001492916.1 CDS A1C_00375 NC_009881.1 58505 58708 D hypothetical protein 58505..58708 Rickettsia akari str. Hartford 5644925 YP_001492917.1 CDS sdhB NC_009881.1 58740 59525 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 58740..59525 Rickettsia akari str. Hartford 5644926 YP_001492918.1 CDS A1C_00385 NC_009881.1 59601 59813 D COG3755 Uncharacterized protein conserved in bacteria; hypothetical protein 59601..59813 Rickettsia akari str. Hartford 5645096 YP_001492919.1 CDS A1C_00390 NC_009881.1 59948 61072 R COG1565 Uncharacterized conserved protein; hypothetical protein complement(59948..61072) Rickettsia akari str. Hartford 5645097 YP_001492920.1 CDS A1C_00395 NC_009881.1 61051 61830 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(61051..61830) Rickettsia akari str. Hartford 5645098 YP_001492921.1 CDS A1C_00400 NC_009881.1 62087 63241 D COG0668 Small-conductance mechanosensitive channel; hypothetical protein 62087..63241 Rickettsia akari str. Hartford 5645099 YP_001492922.1 CDS A1C_00405 NC_009881.1 63370 65052 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 63370..65052 Rickettsia akari str. Hartford 5645100 YP_001492923.1 CDS A1C_00410 NC_009881.1 65052 65597 D COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 65052..65597 Rickettsia akari str. Hartford 5645101 YP_001492924.1 CDS A1C_00415 NC_009881.1 65612 66172 D hypothetical protein 65612..66172 Rickettsia akari str. Hartford 5645102 YP_001492925.1 CDS A1C_00420 NC_009881.1 66476 66859 R hypothetical protein complement(66476..66859) Rickettsia akari str. Hartford 5644992 YP_001492926.1 CDS A1C_00425 NC_009881.1 67369 67653 D COG0500 SAM-dependent methyltransferases; tellurite resistance protein-like protein 67369..67653 Rickettsia akari str. Hartford 5644993 YP_001492927.1 CDS A1C_00430 NC_009881.1 67847 67933 D hypothetical protein 67847..67933 Rickettsia akari str. Hartford 5644994 YP_001492928.1 CDS A1C_00435 NC_009881.1 68372 68674 R COG0242 N-formylmethionyl-tRNA deformylase; polypeptide deformylase complement(68372..68674) Rickettsia akari str. Hartford 5644995 YP_001492929.1 CDS A1C_00440 NC_009881.1 69227 70723 D COG3202 ATP/ADP translocase; ADP,ATP carrier protein 69227..70723 Rickettsia akari str. Hartford 5644996 YP_001492930.1 CDS A1C_00445 NC_009881.1 70807 72096 D COG2271 Sugar phosphate permease; sugar phosphate permease 70807..72096 Rickettsia akari str. Hartford 5644997 YP_001492931.1 CDS ndk NC_009881.1 72124 72546 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 72124..72546 Rickettsia akari str. Hartford 5644998 YP_001492932.1 CDS A1C_00455 NC_009881.1 72550 74418 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 72550..74418 Rickettsia akari str. Hartford 5645365 YP_001492933.1 CDS gidB NC_009881.1 74402 74977 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 74402..74977 Rickettsia akari str. Hartford 5645366 YP_001492934.1 CDS A1C_00465 NC_009881.1 74974 75741 D COG1192 ATPases involved in chromosome partitioning; soj protein 74974..75741 Rickettsia akari str. Hartford 5645367 YP_001492935.1 CDS A1C_00470 NC_009881.1 75728 76588 D COG1475 Predicted transcriptional regulators; stage 0 sporulation protein J 75728..76588 Rickettsia akari str. Hartford 5645368 YP_001492936.1 CDS A1C_00475 NC_009881.1 76776 78443 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 76776..78443 Rickettsia akari str. Hartford 5645369 YP_001492937.1 CDS A1C_00480 NC_009881.1 78446 78763 D hypothetical protein 78446..78763 Rickettsia akari str. Hartford 5645370 YP_001492938.1 CDS A1C_00485 NC_009881.1 78798 79622 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 78798..79622 Rickettsia akari str. Hartford 5645371 YP_001492939.1 CDS A1C_00490 NC_009881.1 80008 80202 D hypothetical protein 80008..80202 Rickettsia akari str. Hartford 5644706 YP_001492940.1 CDS A1C_00495 NC_009881.1 80966 81298 R COG0316 Uncharacterized conserved protein; Iron-sulfur cluster assembly accessory protein complement(80966..81298) Rickettsia akari str. Hartford 5644707 YP_001492941.1 CDS A1C_00500 NC_009881.1 81556 82731 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 81556..82731 Rickettsia akari str. Hartford 5644708 YP_001492942.1 CDS argS NC_009881.1 82718 84448 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 82718..84448 Rickettsia akari str. Hartford 5644709 YP_001492943.1 CDS A1C_00510 NC_009881.1 84595 85269 D hypothetical protein 84595..85269 Rickettsia akari str. Hartford 5644710 YP_001492944.1 CDS A1C_00515 NC_009881.1 85287 85445 D hypothetical protein 85287..85445 Rickettsia akari str. Hartford 5644711 YP_001492945.1 CDS A1C_00520 NC_009881.1 85586 87799 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 85586..87799 Rickettsia akari str. Hartford 5644712 YP_001492946.1 CDS A1C_00525 NC_009881.1 87929 88105 R hypothetical protein complement(87929..88105) Rickettsia akari str. Hartford 5645665 YP_001492947.1 CDS A1C_00530 NC_009881.1 88459 88617 R hypothetical protein complement(88459..88617) Rickettsia akari str. Hartford 5645666 YP_001492948.1 CDS A1C_00535 NC_009881.1 89150 90469 R COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; putative surface antigen complement(89150..90469) Rickettsia akari str. Hartford 5645667 YP_001492949.1 CDS dcd NC_009881.1 90754 91320 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 90754..91320 Rickettsia akari str. Hartford 5645668 YP_001492950.1 CDS A1C_00545 NC_009881.1 91529 91987 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 91529..91987 Rickettsia akari str. Hartford 5645669 YP_001492951.1 CDS A1C_00550 NC_009881.1 92212 92925 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional activator protein CzcR 92212..92925 Rickettsia akari str. Hartford 5645670 YP_001492952.1 CDS queF NC_009881.1 92929 93750 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 92929..93750 Rickettsia akari str. Hartford 5645671 YP_001492953.1 CDS A1C_00560 NC_009881.1 94039 94644 R COG3820 Uncharacterized protein conserved in bacteria; hypothetical protein complement(94039..94644) Rickettsia akari str. Hartford 5645845 YP_001492954.1 CDS A1C_00565 NC_009881.1 94698 96095 R COG1282 NAD/NADP transhydrogenase beta subunit; NAD(p) transhydrogenase subunit beta complement(94698..96095) Rickettsia akari str. Hartford 5645846 YP_001492955.1 CDS A1C_00570 NC_009881.1 96288 97022 R COG3047 Outer membrane protein W; OmpW family outer-membrane protein complement(96288..97022) Rickettsia akari str. Hartford 5645847 YP_001492956.1 CDS A1C_00575 NC_009881.1 97178 98062 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; S-adenosylmethionine transporter 97178..98062 Rickettsia akari str. Hartford 5645848 YP_001492957.1 CDS A1C_00580 NC_009881.1 98049 99305 D COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter 98049..99305 Rickettsia akari str. Hartford 5645849 YP_001492958.1 CDS secG NC_009881.1 98213 98392 R preprotein translocase subunit SecG complement(98213..98392) Rickettsia akari str. Hartford 5645850 YP_001492959.1 CDS A1C_00590 NC_009881.1 99721 99795 D hypothetical protein 99721..99795 Rickettsia akari str. Hartford 5645851 YP_001492960.1 CDS secG NC_009881.1 99977 100279 D preprotein translocase subunit SecG 99977..100279 Rickettsia akari str. Hartford 5645320 YP_001492961.1 CDS A1C_00600 NC_009881.1 100596 101300 D COG1738 Uncharacterized conserved protein; hypothetical protein 100596..101300 Rickettsia akari str. Hartford 5645321 YP_001492962.1 CDS A1C_00605 NC_009881.1 101331 106664 R COG1196 Chromosome segregation ATPases; hypothetical protein complement(101331..106664) Rickettsia akari str. Hartford 5645322 YP_001492963.1 CDS A1C_00610 NC_009881.1 107146 112578 R hypothetical protein complement(107146..112578) Rickettsia akari str. Hartford 5645323 YP_001492964.1 CDS cysS NC_009881.1 112799 114178 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 112799..114178 Rickettsia akari str. Hartford 5645324 YP_001492965.1 CDS rpsB NC_009881.1 114515 115402 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 114515..115402 Rickettsia akari str. Hartford 5645687 YP_001492966.1 CDS tsf NC_009881.1 115646 116575 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 115646..116575 Rickettsia akari str. Hartford 5645688 YP_001492967.1 CDS A1C_00630 NC_009881.1 117140 117250 R hypothetical protein complement(117140..117250) Rickettsia akari str. Hartford 5645689 YP_001492968.1 CDS A1C_00635 NC_009881.1 117658 117897 R hypothetical protein complement(117658..117897) Rickettsia akari str. Hartford 5645690 YP_001492969.1 CDS A1C_00640 NC_009881.1 117994 119250 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(117994..119250) Rickettsia akari str. Hartford 5645691 YP_001492970.1 CDS A1C_00645 NC_009881.1 119247 119903 R COG2121 Uncharacterized protein conserved in bacteria; hypothetical protein complement(119247..119903) Rickettsia akari str. Hartford 5645692 YP_001492971.1 CDS A1C_00650 NC_009881.1 120021 121220 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(120021..121220) Rickettsia akari str. Hartford 5645693 YP_001492972.1 CDS A1C_00655 NC_009881.1 121439 122443 D COG0457 FOG: TPR repeat; hypothetical protein 121439..122443 Rickettsia akari str. Hartford 5645284 YP_001492973.1 CDS A1C_00660 NC_009881.1 122448 123203 D COG2853 Surface lipoprotein; VacJ lipoprotein precursor 122448..123203 Rickettsia akari str. Hartford 5645285 YP_001492974.1 CDS A1C_00665 NC_009881.1 123223 123822 D COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component; hypothetical protein 123223..123822 Rickettsia akari str. Hartford 5645286 YP_001492975.1 CDS A1C_00670 NC_009881.1 124078 124305 R COG1943 Transposase and inactivated derivatives; transposase IS200-family protein complement(124078..124305) Rickettsia akari str. Hartford 5645287 YP_001492976.1 CDS A1C_00675 NC_009881.1 124829 124984 D hypothetical protein 124829..124984 Rickettsia akari str. Hartford 5645288 YP_001492977.1 CDS A1C_00680 NC_009881.1 124962 125144 D hypothetical protein 124962..125144 Rickettsia akari str. Hartford 5645289 YP_001492978.1 CDS A1C_00685 NC_009881.1 125514 125651 R hypothetical protein complement(125514..125651) Rickettsia akari str. Hartford 5645290 YP_001492979.1 CDS A1C_00690 NC_009881.1 125999 126250 R alpha/beta hydrolase superfamily esterase complement(125999..126250) Rickettsia akari str. Hartford 5645473 YP_001492980.1 CDS A1C_00695 NC_009881.1 126229 126399 R alpha/beta hydrolase superfamily esterase complement(126229..126399) Rickettsia akari str. Hartford 5645474 YP_001492981.1 CDS A1C_00700 NC_009881.1 126589 127080 R hypothetical protein complement(126589..127080) Rickettsia akari str. Hartford 5645475 YP_001492982.1 CDS A1C_00705 NC_009881.1 127170 128330 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(127170..128330) Rickettsia akari str. Hartford 5645476 YP_001492983.1 CDS A1C_00710 NC_009881.1 128643 129836 R COG1398 Fatty-acid desaturase; Acyl-CoA desaturase 1 complement(128643..129836) Rickettsia akari str. Hartford 5645477 YP_001492984.1 CDS A1C_00715 NC_009881.1 130177 130353 D COG0462 Phosphoribosylpyrophosphate synthetase; ribose-phosphate pyrophosphokinase 130177..130353 Rickettsia akari str. Hartford 5645478 YP_001492985.1 CDS alr NC_009881.1 130548 130682 D COG0462 Phosphoribosylpyrophosphate synthetase; alanine racemase 130548..130682 Rickettsia akari str. Hartford 5645479 YP_001492986.1 CDS A1C_00725 NC_009881.1 130691 130849 D hypothetical protein 130691..130849 Rickettsia akari str. Hartford 5644890 YP_001492987.1 CDS alr NC_009881.1 130846 131913 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 130846..131913 Rickettsia akari str. Hartford 5644891 YP_001492988.1 CDS A1C_00735 NC_009881.1 132123 132902 D COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; ABC transporter permease 132123..132902 Rickettsia akari str. Hartford 5644892 YP_001492989.1 CDS A1C_00740 NC_009881.1 133135 133890 D COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; ribonucleotide ABC transporter ATP-binding protein 133135..133890 Rickettsia akari str. Hartford 5644893 YP_001492990.1 CDS A1C_00745 NC_009881.1 133892 134140 D hypothetical protein 133892..134140 Rickettsia akari str. Hartford 5644894 YP_001492991.1 CDS rpmB NC_009881.1 134219 134512 D required for 70S ribosome assembly; 50S ribosomal protein L28 134219..134512 Rickettsia akari str. Hartford 5644895 YP_001492992.1 CDS A1C_00755 NC_009881.1 134509 134745 D RpmE; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 134509..134745 Rickettsia akari str. Hartford 5644896 YP_001492993.1 CDS engB NC_009881.1 135384 136022 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 135384..136022 Rickettsia akari str. Hartford 5645784 YP_001492994.1 CDS A1C_00780 NC_009881.1 136910 137197 D COG3702 Type IV secretory pathway, VirB3 components; type IV secretion system protein VirB3 136910..137197 Rickettsia akari str. Hartford 5645785 YP_001492995.1 CDS A1C_00785 NC_009881.1 137496 139913 D COG3451 Type IV secretory pathway, VirB4 components; type IV secretion system ATPase VirB4 137496..139913 Rickettsia akari str. Hartford 5645786 YP_001492996.1 CDS A1C_00790 NC_009881.1 140088 143114 D COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 140088..143114 Rickettsia akari str. Hartford 5645787 YP_001492997.1 CDS A1C_00795 NC_009881.1 143101 145119 D COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 143101..145119 Rickettsia akari str. Hartford 5645788 YP_001492998.1 CDS A1C_00800 NC_009881.1 145126 148056 D COG3704 Type IV secretory pathway, VirB6 components; hypothetical protein 145126..148056 Rickettsia akari str. Hartford 5645497 YP_001492999.1 CDS A1C_00805 NC_009881.1 148265 150895 D COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 148265..150895 Rickettsia akari str. Hartford 5645498 YP_001493000.1 CDS A1C_00810 NC_009881.1 151083 154547 D COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 151083..154547 Rickettsia akari str. Hartford 5645499 YP_001493001.1 CDS A1C_00815 NC_009881.1 154665 154781 D antitoxin of toxin-antitoxin system VapB 154665..154781 Rickettsia akari str. Hartford 5645500 YP_001493002.1 CDS A1C_00820 NC_009881.1 154859 155110 D COG1487 Predicted nucleic acid-binding protein, contains PIN domain; toxin of toxin-antitoxin system 154859..155110 Rickettsia akari str. Hartford 5645501 YP_001493003.1 CDS A1C_00825 NC_009881.1 155369 156418 D catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs; phosphate acetyltransferase 155369..156418 Rickettsia akari str. Hartford 5645502 YP_001493004.1 CDS A1C_00830 NC_009881.1 156420 157577 D COG0282 Acetate kinase; acetate kinase 156420..157577 Rickettsia akari str. Hartford 5645503 YP_001493005.1 CDS trmD NC_009881.1 157903 158067 D tRNA (guanine-N(1)-)-methyltransferase 157903..158067 Rickettsia akari str. Hartford 5645089 YP_001493006.1 CDS trmD NC_009881.1 158144 158848 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 158144..158848 Rickettsia akari str. Hartford 5645090 YP_001493007.1 CDS rplS NC_009881.1 158864 159280 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 158864..159280 Rickettsia akari str. Hartford 5645091 YP_001493008.1 CDS A1C_00850 NC_009881.1 159658 159894 R COG3750 Uncharacterized protein conserved in bacteria; hypothetical protein complement(159658..159894) Rickettsia akari str. Hartford 5645092 YP_001493009.1 CDS secF NC_009881.1 160092 161018 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 160092..161018 Rickettsia akari str. Hartford 5645093 YP_001493010.1 CDS A1C_00860 NC_009881.1 161250 162521 D part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 161250..162521 Rickettsia akari str. Hartford 5645094 YP_001493011.1 CDS A1C_00865 NC_009881.1 162646 163446 D COG0681 Signal peptidase I; Signal peptidase I 162646..163446 Rickettsia akari str. Hartford 5645095 YP_001493012.1 CDS rnc NC_009881.1 163446 164129 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 163446..164129 Rickettsia akari str. Hartford 5645325 YP_001493013.1 CDS era NC_009881.1 164122 165003 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 164122..165003 Rickettsia akari str. Hartford 5645326 YP_001493014.1 CDS ruvC NC_009881.1 165101 165574 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 165101..165574 Rickettsia akari str. Hartford 5645327 YP_001493015.1 CDS A1C_00885 NC_009881.1 165571 166266 D COG0565 rRNA methylase; tRNA/rRNA methyltransferase 165571..166266 Rickettsia akari str. Hartford 5645328 YP_001493016.1 CDS A1C_00890 NC_009881.1 166641 166775 R nucleotidyltransferase complement(166641..166775) Rickettsia akari str. Hartford 5645329 YP_001493017.1 CDS A1C_00895 NC_009881.1 166951 168132 R COG3660 Predicted nucleoside-diphosphate-sugar epimerase; hypothetical protein complement(166951..168132) Rickettsia akari str. Hartford 5645330 YP_001493018.1 CDS A1C_00900 NC_009881.1 168129 169091 R COG0489 ATPases involved in chromosome partitioning; Mrp protein complement(168129..169091) Rickettsia akari str. Hartford 5645331 YP_001493019.1 CDS A1C_00905 NC_009881.1 169191 170228 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; protease activity modulator HflK 169191..170228 Rickettsia akari str. Hartford 5645172 YP_001493020.1 CDS A1C_00910 NC_009881.1 170246 170395 D hypothetical protein 170246..170395 Rickettsia akari str. Hartford 5645173 YP_001493021.1 CDS A1C_00915 NC_009881.1 170371 171231 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; membrane protease subunit stomatin/prohibitin-like protein 170371..171231 Rickettsia akari str. Hartford 5645174 YP_001493022.1 CDS A1C_00920 NC_009881.1 171236 172774 D COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; serine protease 171236..172774 Rickettsia akari str. Hartford 5645175 YP_001493023.1 CDS A1C_00925 NC_009881.1 172853 173596 D COG1054 Predicted sulfurtransferase; hypothetical protein 172853..173596 Rickettsia akari str. Hartford 5645176 YP_001493024.1 CDS A1C_00930 NC_009881.1 173782 174156 D COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; succinate dehydrogenase cytochrome b-556 subunit 173782..174156 Rickettsia akari str. Hartford 5645177 YP_001493025.1 CDS A1C_00935 NC_009881.1 174317 174409 D hypothetical protein 174317..174409 Rickettsia akari str. Hartford 5645178 YP_001493026.1 CDS A1C_00940 NC_009881.1 174409 174786 D COG2142 Succinate dehydrogenase, hydrophobic anchor subunit; succinate dehydrogenase hydrophobic membrane anchor protein 174409..174786 Rickettsia akari str. Hartford 5645760 YP_001493027.1 CDS A1C_00945 NC_009881.1 174783 174938 D hypothetical protein 174783..174938 Rickettsia akari str. Hartford 5645761 YP_001493028.1 CDS A1C_00950 NC_009881.1 175024 175290 D toxin of toxin-antitoxin (TA) system ParE 175024..175290 Rickettsia akari str. Hartford 5645762 YP_001493029.1 CDS sdhA NC_009881.1 175325 177115 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 175325..177115 Rickettsia akari str. Hartford 5645763 YP_001493030.1 CDS A1C_00960 NC_009881.1 177373 178029 D COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 177373..178029 Rickettsia akari str. Hartford 5645764 YP_001493031.1 CDS rpsL NC_009881.1 178187 178576 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 178187..178576 Rickettsia akari str. Hartford 5645765 YP_001493032.1 CDS A1C_00970 NC_009881.1 178603 179085 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 178603..179085 Rickettsia akari str. Hartford 5645766 YP_001493033.1 CDS A1C_00975 NC_009881.1 179099 181198 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 179099..181198 Rickettsia akari str. Hartford 5645702 YP_001493034.1 CDS secE NC_009881.1 181572 181778 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 181572..181778 Rickettsia akari str. Hartford 5645704 YP_001493035.1 CDS nusG NC_009881.1 181789 182367 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 181789..182367 Rickettsia akari str. Hartford 5645705 YP_001493036.1 CDS rplK NC_009881.1 182582 183019 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 182582..183019 Rickettsia akari str. Hartford 5645706 YP_001493037.1 CDS rplA NC_009881.1 183025 183744 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 183025..183744 Rickettsia akari str. Hartford 5645707 YP_001493038.1 CDS rplJ NC_009881.1 183846 184355 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 183846..184355 Rickettsia akari str. Hartford 5644713 YP_001493039.1 CDS rplL NC_009881.1 184545 184919 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 184545..184919 Rickettsia akari str. Hartford 5644714 YP_001493040.1 CDS rpoB NC_009881.1 185804 189925 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 185804..189925 Rickettsia akari str. Hartford 5644715 YP_001493041.1 CDS A1C_01015 NC_009881.1 190244 194362 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 190244..194362 Rickettsia akari str. Hartford 5644716 YP_001493042.1 CDS A1C_01020 NC_009881.1 194789 195817 R hypothetical protein complement(194789..195817) Rickettsia akari str. Hartford 5644717 YP_001493043.1 CDS A1C_01025 NC_009881.1 196090 197574 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 196090..197574 Rickettsia akari str. Hartford 5644718 YP_001493044.1 CDS A1C_01030 NC_009881.1 197755 198555 D COG1192 ATPases involved in chromosome partitioning; chromosome partitioning protein 197755..198555 Rickettsia akari str. Hartford 5644719 YP_001493045.1 CDS A1C_01035 NC_009881.1 198641 199075 D hypothetical protein 198641..199075 Rickettsia akari str. Hartford 5645716 YP_001493046.1 CDS aspS NC_009881.1 199154 200962 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 199154..200962 Rickettsia akari str. Hartford 5645717 YP_001493047.1 CDS A1C_01045 NC_009881.1 201228 203342 R hypothetical protein complement(201228..203342) Rickettsia akari str. Hartford 5645718 YP_001493048.1 CDS A1C_01050 NC_009881.1 203364 204074 R COG0670 Integral membrane protein, interacts with FtsH; integral membrane protein complement(203364..204074) Rickettsia akari str. Hartford 5645719 YP_001493049.1 CDS A1C_01055 NC_009881.1 204120 204857 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(204120..204857) Rickettsia akari str. Hartford 5645720 YP_001493050.1 CDS A1C_01060 NC_009881.1 204876 205361 R COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein complement(204876..205361) Rickettsia akari str. Hartford 5645721 YP_001493051.1 CDS A1C_01065 NC_009881.1 205346 206071 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein complement(205346..206071) Rickettsia akari str. Hartford 5645722 YP_001493052.1 CDS gatB NC_009881.1 206276 207727 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(206276..207727) Rickettsia akari str. Hartford 5645053 YP_001493053.1 CDS gatA NC_009881.1 207904 209382 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(207904..209382) Rickettsia akari str. Hartford 5645054 YP_001493054.1 CDS gatC NC_009881.1 209385 209687 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(209385..209687) Rickettsia akari str. Hartford 5645055 YP_001493055.1 CDS frr NC_009881.1 209843 209989 R ribosome recycling factor complement(209843..209989) Rickettsia akari str. Hartford 5645056 YP_001493056.1 CDS frr NC_009881.1 210244 210804 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(210244..210804) Rickettsia akari str. Hartford 5645057 YP_001493057.1 CDS pyrH NC_009881.1 211018 211755 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(211018..211755) Rickettsia akari str. Hartford 5645058 YP_001493058.1 CDS A1C_01100 NC_009881.1 211759 212076 R subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E complement(211759..212076) Rickettsia akari str. Hartford 5645059 YP_001493059.1 CDS A1C_01105 NC_009881.1 212060 213619 R COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein B complement(212060..213619) Rickettsia akari str. Hartford 5645138 YP_001493060.1 CDS A1C_01110 NC_009881.1 213859 214062 D COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; hypothetical protein 213859..214062 Rickettsia akari str. Hartford 5645139 YP_001493061.1 CDS A1C_01115 NC_009881.1 215437 215658 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 215437..215658 Rickettsia akari str. Hartford 5645140 YP_001493062.1 CDS A1C_01120 NC_009881.1 215661 215813 R hypothetical protein complement(215661..215813) Rickettsia akari str. Hartford 5645141 YP_001493063.1 CDS A1C_01125 NC_009881.1 216379 218673 R COG4775 Outer membrane protein/protective antigen OMA87; Outer membrane protein omp1 complement(216379..218673) Rickettsia akari str. Hartford 5645143 YP_001493064.1 CDS A1C_01130 NC_009881.1 218955 220028 R COG0750 Predicted membrane-associated Zn-dependent proteases 1; membrane-associated zinc metalloprotease complement(218955..220028) Rickettsia akari str. Hartford 5645194 YP_001493065.1 CDS nusB NC_009881.1 220211 220681 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 220211..220681 Rickettsia akari str. Hartford 5645195 YP_001493066.1 CDS A1C_01140 NC_009881.1 220678 221361 D COG0293 23S rRNA methylase; ribosomal RNA large subunit methyltransferase J 220678..221361 Rickettsia akari str. Hartford 5645196 YP_001493067.1 CDS A1C_01145 NC_009881.1 221399 222481 R hypothetical protein complement(221399..222481) Rickettsia akari str. Hartford 5645197 YP_001493068.1 CDS A1C_01150 NC_009881.1 222602 222763 D hypothetical protein 222602..222763 Rickettsia akari str. Hartford 5645198 YP_001493069.1 CDS A1C_01155 NC_009881.1 222823 223554 D hypothetical protein 222823..223554 Rickettsia akari str. Hartford 5645199 YP_001493070.1 CDS A1C_01160 NC_009881.1 223613 224053 R COG2867 Oligoketide cyclase/lipid transport protein; hypothetical protein complement(223613..224053) Rickettsia akari str. Hartford 5645200 YP_001493071.1 CDS A1C_01165 NC_009881.1 224058 224318 R multidrug ABC transporter ATPase and permease complement(224058..224318) Rickettsia akari str. Hartford 5645615 YP_001493072.1 CDS A1C_01170 NC_009881.1 224328 225092 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 224328..225092 Rickettsia akari str. Hartford 5645616 YP_001493073.1 CDS A1C_01180 NC_009881.1 225716 225811 R hypothetical protein complement(225716..225811) Rickettsia akari str. Hartford 5645617 YP_001493074.1 CDS A1C_01205 NC_009881.1 227750 227869 D hypothetical protein 227750..227869 Rickettsia akari str. Hartford 5645618 YP_001493075.1 CDS A1C_01215 NC_009881.1 228276 228395 R hydrophobe/amphiphile efflux-1 HAE1 family protein complement(228276..228395) Rickettsia akari str. Hartford 5645619 YP_001493076.1 CDS A1C_01220 NC_009881.1 228997 229329 D COG0776 Bacterial nucleoid DNA-binding protein; DNA-binding protein HU 228997..229329 Rickettsia akari str. Hartford 5645620 YP_001493077.1 CDS A1C_01225 NC_009881.1 229385 230263 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 229385..230263 Rickettsia akari str. Hartford 5645621 YP_001493078.1 CDS A1C_01230 NC_009881.1 230546 231895 D COG0541 Signal recognition particle GTPase; Signal recognition particle protein 230546..231895 Rickettsia akari str. Hartford 5644999 YP_001493079.1 CDS A1C_01265 NC_009881.1 235282 236463 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 235282..236463 Rickettsia akari str. Hartford 5645000 YP_001493080.1 CDS A1C_01270 NC_009881.1 236630 236983 R hypothetical protein complement(236630..236983) Rickettsia akari str. Hartford 5645001 YP_001493081.1 CDS A1C_01275 NC_009881.1 237617 237829 R hypothetical protein complement(237617..237829) Rickettsia akari str. Hartford 5645002 YP_001493082.1 CDS A1C_01280 NC_009881.1 238225 239424 R COG1301 Na+/H+-dicarboxylate symporters; proton/sodium-glutamate symport protein complement(238225..239424) Rickettsia akari str. Hartford 5645003 YP_001493083.1 CDS A1C_01285 NC_009881.1 239448 239762 R COG1324 Uncharacterized protein involved in tolerance to divalent cations; divalent cation tolerance protein complement(239448..239762) Rickettsia akari str. Hartford 5645004 YP_001493084.1 CDS A1C_01290 NC_009881.1 239765 240208 R COG0720 6-pyruvoyl-tetrahydropterin synthase; hypothetical protein complement(239765..240208) Rickettsia akari str. Hartford 5645005 YP_001493085.1 CDS A1C_01295 NC_009881.1 240318 241520 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase complement(240318..241520) Rickettsia akari str. Hartford 5645020 YP_001493086.1 CDS sucA NC_009881.1 241658 244444 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(241658..244444) Rickettsia akari str. Hartford 5645021 YP_001493087.1 CDS A1C_01305 NC_009881.1 244580 246067 R COG2317 Zn-dependent carboxypeptidase; thermostable carboxypeptidase complement(244580..246067) Rickettsia akari str. Hartford 5645022 YP_001493088.1 CDS A1C_01310 NC_009881.1 246246 247886 R COG0497 ATPase involved in DNA repair; DNA repair protein RecN complement(246246..247886) Rickettsia akari str. Hartford 5645023 YP_001493089.1 CDS A1C_01315 NC_009881.1 248071 248814 R COG4105 DNA uptake lipoprotein; hypothetical protein complement(248071..248814) Rickettsia akari str. Hartford 5645024 YP_001493090.1 CDS A1C_01320 NC_009881.1 249082 249276 R COG4572 Putative cation transport regulator; cation transport regulator ChaB complement(249082..249276) Rickettsia akari str. Hartford 5645025 YP_001493091.1 CDS A1C_01325 NC_009881.1 249502 250617 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(249502..250617) Rickettsia akari str. Hartford 5645026 YP_001493092.1 CDS dnaK NC_009881.1 250806 252689 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(250806..252689) Rickettsia akari str. Hartford 5644876 YP_001493093.1 CDS A1C_01335 NC_009881.1 252930 254423 D COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; heat shock protease 252930..254423 Rickettsia akari str. Hartford 5644877 YP_001493094.1 CDS A1C_01340 NC_009881.1 254761 255252 D ankyrin repeat-containing protein 254761..255252 Rickettsia akari str. Hartford 5644878 YP_001493095.1 CDS A1C_01345 NC_009881.1 255508 255852 R hypothetical protein complement(255508..255852) Rickettsia akari str. Hartford 5644879 YP_001493096.1 CDS A1C_01350 NC_009881.1 256028 256501 D hypothetical protein 256028..256501 Rickettsia akari str. Hartford 5644880 YP_001493097.1 CDS holA NC_009881.1 256509 257489 D required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 256509..257489 Rickettsia akari str. Hartford 5644881 YP_001493098.1 CDS A1C_01360 NC_009881.1 257689 258228 D COG2941 Ubiquinone biosynthesis protein COQ7; ubiquinone biosynthesis protein Coq7 257689..258228 Rickettsia akari str. Hartford 5644882 YP_001493099.1 CDS A1C_01365 NC_009881.1 258256 258414 R hypothetical protein complement(258256..258414) Rickettsia akari str. Hartford 5644766 YP_001493100.1 CDS A1C_01370 NC_009881.1 258912 259748 D COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; cytochrome c oxidase subunit III 258912..259748 Rickettsia akari str. Hartford 5644767 YP_001493101.1 CDS A1C_01375 NC_009881.1 259904 260263 D hypothetical protein 259904..260263 Rickettsia akari str. Hartford 5644768 YP_001493102.1 CDS A1C_01380 NC_009881.1 260562 261182 R hypothetical protein complement(260562..261182) Rickettsia akari str. Hartford 5644769 YP_001493103.1 CDS dapD NC_009881.1 261266 262090 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 261266..262090 Rickettsia akari str. Hartford 5644770 YP_001493104.1 CDS A1C_01390 NC_009881.1 262627 262734 R hypothetical protein complement(262627..262734) Rickettsia akari str. Hartford 5644771 YP_001493105.1 CDS A1C_01395 NC_009881.1 262758 263039 R COG0457 FOG: TPR repeat; hypothetical protein complement(262758..263039) Rickettsia akari str. Hartford 5644772 YP_001493106.1 CDS A1C_01400 NC_009881.1 263531 263791 R hypothetical protein complement(263531..263791) Rickettsia akari str. Hartford 5645622 YP_001493107.1 CDS A1C_01405 NC_009881.1 263824 263982 R hypothetical protein complement(263824..263982) Rickettsia akari str. Hartford 5645623 YP_001493108.1 CDS A1C_01410 NC_009881.1 264225 266579 R COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; bifunctional penicillin-binding protein 1C complement(264225..266579) Rickettsia akari str. Hartford 5645624 YP_001493109.1 CDS A1C_01415 NC_009881.1 267090 267401 D cell surface antigen-like protein Sca8 267090..267401 Rickettsia akari str. Hartford 5645625 YP_001493110.1 CDS A1C_01420 NC_009881.1 267472 267561 D hypothetical protein 267472..267561 Rickettsia akari str. Hartford 5645626 YP_001493111.1 CDS A1C_01425 NC_009881.1 267826 268143 D hypothetical protein 267826..268143 Rickettsia akari str. Hartford 5645627 YP_001493112.1 CDS A1C_01430 NC_009881.1 268272 268595 D hypothetical protein 268272..268595 Rickettsia akari str. Hartford 5645628 YP_001493113.1 CDS A1C_01435 NC_009881.1 268704 268790 D hypothetical protein 268704..268790 Rickettsia akari str. Hartford 5645737 YP_001493114.1 CDS A1C_01440 NC_009881.1 268854 268961 D hypothetical protein 268854..268961 Rickettsia akari str. Hartford 5645738 YP_001493115.1 CDS A1C_01445 NC_009881.1 269047 269262 D cell surface antigen-like protein Sca8 269047..269262 Rickettsia akari str. Hartford 5645739 YP_001493116.1 CDS A1C_01450 NC_009881.1 269373 269534 D cell surface antigen-like protein Sca8 269373..269534 Rickettsia akari str. Hartford 5645740 YP_001493117.1 CDS A1C_01455 NC_009881.1 269709 270155 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; universal stress protein UspA complement(269709..270155) Rickettsia akari str. Hartford 5645741 YP_001493118.1 CDS A1C_01460 NC_009881.1 270165 271106 R COG2358 TRAP-type uncharacterized transport system, periplasmic component; hypothetical protein complement(270165..271106) Rickettsia akari str. Hartford 5645742 YP_001493119.1 CDS A1C_01465 NC_009881.1 271111 272181 R hypothetical protein complement(271111..272181) Rickettsia akari str. Hartford 5645743 YP_001493120.1 CDS A1C_01470 NC_009881.1 272194 272532 R COG0633 Ferredoxin; ferredoxin complement(272194..272532) Rickettsia akari str. Hartford 5644927 YP_001493121.1 CDS hscA NC_009881.1 272594 274381 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(272594..274381) Rickettsia akari str. Hartford 5644928 YP_001493122.1 CDS hscB NC_009881.1 274372 274872 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(274372..274872) Rickettsia akari str. Hartford 5644929 YP_001493123.1 CDS rnhB NC_009881.1 275014 275595 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 275014..275595 Rickettsia akari str. Hartford 5644930 YP_001493124.1 CDS A1C_01490 NC_009881.1 275759 277744 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(275759..277744) Rickettsia akari str. Hartford 5644931 YP_001493125.1 CDS A1C_01495 NC_009881.1 277815 278108 D COG0695 Glutaredoxin and related proteins; glutaredoxin 277815..278108 Rickettsia akari str. Hartford 5644932 YP_001493126.1 CDS A1C_01525 NC_009881.1 280551 283247 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 280551..283247 Rickettsia akari str. Hartford 5644933 YP_001493127.1 CDS A1C_01530 NC_009881.1 283783 284058 R hypothetical protein complement(283783..284058) Rickettsia akari str. Hartford 5645573 YP_001493128.1 CDS def NC_009881.1 284970 285086 D peptide deformylase 284970..285086 Rickettsia akari str. Hartford 5645574 YP_001493129.1 CDS A1C_01550 NC_009881.1 285238 285420 D hypothetical protein 285238..285420 Rickettsia akari str. Hartford 5645575 YP_001493130.1 CDS A1C_01555 NC_009881.1 285477 285662 R hypothetical protein complement(285477..285662) Rickettsia akari str. Hartford 5645576 YP_001493131.1 CDS def NC_009881.1 285876 286403 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 285876..286403 Rickettsia akari str. Hartford 5645577 YP_001493132.1 CDS fmt NC_009881.1 286415 287311 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 286415..287311 Rickettsia akari str. Hartford 5645578 YP_001493133.1 CDS A1C_01570 NC_009881.1 287428 287529 D hypothetical protein 287428..287529 Rickettsia akari str. Hartford 5645579 YP_001493134.1 CDS A1C_01575 NC_009881.1 287754 287915 D hypothetical protein 287754..287915 Rickettsia akari str. Hartford 5645256 YP_001493135.1 CDS A1C_01580 NC_009881.1 292449 293501 R COG1485 Predicted ATPase; putative ATPase n2B complement(292449..293501) Rickettsia akari str. Hartford 5645258 YP_001493136.1 CDS A1C_01585 NC_009881.1 293718 294833 R COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(293718..294833) Rickettsia akari str. Hartford 5645259 YP_001493137.1 CDS A1C_01590 NC_009881.1 295270 295749 D COG0666 FOG: Ankyrin repeat; hypothetical protein 295270..295749 Rickettsia akari str. Hartford 5645260 YP_001493138.1 CDS A1C_01595 NC_009881.1 295792 296037 D hypothetical protein 295792..296037 Rickettsia akari str. Hartford 5645261 YP_001493139.1 CDS A1C_01600 NC_009881.1 296235 298004 R COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATP-binding protein complement(296235..298004) Rickettsia akari str. Hartford 5645432 YP_001493140.1 CDS A1C_01605 NC_009881.1 298188 298469 D hypothetical protein 298188..298469 Rickettsia akari str. Hartford 5645433 YP_001493141.1 CDS A1C_01610 NC_009881.1 298679 300034 D COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome d ubiquinol oxidase subunit I 298679..300034 Rickettsia akari str. Hartford 5645434 YP_001493142.1 CDS A1C_01615 NC_009881.1 300129 301148 D COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome d ubiquinol oxidase subunit II 300129..301148 Rickettsia akari str. Hartford 5645435 YP_001493143.1 CDS A1C_01620 NC_009881.1 301395 302270 D COG0463 Glycosyltransferases involved in cell wall biogenesis; beta 1,4 glucosyltransferase 301395..302270 Rickettsia akari str. Hartford 5645436 YP_001493144.1 CDS A1C_01625 NC_009881.1 302409 303647 D COG0612 Predicted Zn-dependent peptidases; hypothetical protein 302409..303647 Rickettsia akari str. Hartford 5645437 YP_001493145.1 CDS A1C_01630 NC_009881.1 303728 304438 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 303728..304438 Rickettsia akari str. Hartford 5645438 YP_001493146.1 CDS A1C_01635 NC_009881.1 304742 306343 D hypothetical protein 304742..306343 Rickettsia akari str. Hartford 5645658 YP_001493147.1 CDS thrS NC_009881.1 306467 308374 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 306467..308374 Rickettsia akari str. Hartford 5645659 YP_001493148.1 CDS A1C_01645 NC_009881.1 308762 308878 D multidrug ABC transporter ATPase and permease 308762..308878 Rickettsia akari str. Hartford 5645660 YP_001493149.1 CDS A1C_01650 NC_009881.1 308967 309164 R hypothetical protein complement(308967..309164) Rickettsia akari str. Hartford 5645661 YP_001493150.1 CDS A1C_01655 NC_009881.1 309568 309975 R hypothetical protein complement(309568..309975) Rickettsia akari str. Hartford 5645662 YP_001493151.1 CDS A1C_01660 NC_009881.1 310589 310714 R hypothetical protein complement(310589..310714) Rickettsia akari str. Hartford 5645663 YP_001493152.1 CDS A1C_01665 NC_009881.1 310788 311063 R hypothetical protein complement(310788..311063) Rickettsia akari str. Hartford 5645664 YP_001493153.1 CDS A1C_01670 NC_009881.1 311388 312752 D COG1538 Outer membrane protein; TolC family type I secretion outer membrane protein 311388..312752 Rickettsia akari str. Hartford 5644970 YP_001493154.1 CDS A1C_01675 NC_009881.1 312754 313152 D COG3827 Uncharacterized protein conserved in bacteria; hypothetical protein 312754..313152 Rickettsia akari str. Hartford 5644971 YP_001493155.1 CDS A1C_01680 NC_009881.1 313215 315029 D COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein 313215..315029 Rickettsia akari str. Hartford 5644972 YP_001493156.1 CDS A1C_01685 NC_009881.1 315190 317178 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 315190..317178 Rickettsia akari str. Hartford 5644973 YP_001493157.1 CDS A1C_01690 NC_009881.1 317290 318639 D COG0793 Periplasmic protease; tail-specific protease 317290..318639 Rickettsia akari str. Hartford 5644974 YP_001493158.1 CDS A1C_01695 NC_009881.1 318835 320328 D COG0642 Signal transduction histidine kinase; histidine kinase sensor protein 318835..320328 Rickettsia akari str. Hartford 5644975 YP_001493159.1 CDS A1C_01700 NC_009881.1 320547 321284 D COG1729 Uncharacterized protein conserved in bacteria; hypothetical protein 320547..321284 Rickettsia akari str. Hartford 5644976 YP_001493160.1 CDS A1C_01705 NC_009881.1 321297 321959 D COG1038 Pyruvate carboxylase; hypothetical protein 321297..321959 Rickettsia akari str. Hartford 5645359 YP_001493161.1 CDS A1C_01710 NC_009881.1 321982 323226 D COG1520 FOG: WD40-like repeat; WD-40 repeat-containing protein 321982..323226 Rickettsia akari str. Hartford 5645360 YP_001493162.1 CDS rplM NC_009881.1 323320 323787 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 323320..323787 Rickettsia akari str. Hartford 5645361 YP_001493163.1 CDS rpsI NC_009881.1 323794 324279 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 323794..324279 Rickettsia akari str. Hartford 5645362 YP_001493164.1 CDS A1C_01725 NC_009881.1 324904 325011 D hypothetical protein 324904..325011 Rickettsia akari str. Hartford 5645364 YP_001493165.1 CDS A1C_01730 NC_009881.1 325345 325476 D COG2154 Pterin-4a-carbinolamine dehydratase; putative pterin-4-alpha-carbinolamine dehydratase (PHS) 325345..325476 Rickettsia akari str. Hartford 5644963 YP_001493166.1 CDS A1C_01735 NC_009881.1 325911 326312 D hypothetical protein 325911..326312 Rickettsia akari str. Hartford 5644964 YP_001493167.1 CDS A1C_01740 NC_009881.1 326651 327136 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(326651..327136) Rickettsia akari str. Hartford 5644965 YP_001493168.1 CDS pleD NC_009881.1 327160 328512 R involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD complement(327160..328512) Rickettsia akari str. Hartford 5644966 YP_001493169.1 CDS A1C_01750 NC_009881.1 328588 329154 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 328588..329154 Rickettsia akari str. Hartford 5644967 YP_001493170.1 CDS A1C_01755 NC_009881.1 329164 329910 D COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; extragenic suppressor protein SuhB 329164..329910 Rickettsia akari str. Hartford 5644968 YP_001493171.1 CDS A1C_01760 NC_009881.1 330151 330474 D hypothetical protein 330151..330474 Rickettsia akari str. Hartford 5644969 YP_001493172.1 CDS A1C_01765 NC_009881.1 330554 331249 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 330554..331249 Rickettsia akari str. Hartford 5645608 YP_001493173.1 CDS A1C_01770 NC_009881.1 331415 332182 D COG1183 Phosphatidylserine synthase; CDP-diacylglycerol--serine O-phosphatidyltransferase 331415..332182 Rickettsia akari str. Hartford 5645609 YP_001493174.1 CDS A1C_01775 NC_009881.1 332191 333243 D COG1566 Multidrug resistance efflux pump; multidrug resistance protein A 332191..333243 Rickettsia akari str. Hartford 5645610 YP_001493175.1 CDS A1C_01780 NC_009881.1 333441 333518 D hypothetical protein 333441..333518 Rickettsia akari str. Hartford 5645611 YP_001493176.1 CDS A1C_01785 NC_009881.1 333681 333884 R hypothetical protein complement(333681..333884) Rickettsia akari str. Hartford 5645612 YP_001493177.1 CDS A1C_01790 NC_009881.1 333881 334123 R COG0271 Stress-induced morphogen (activity unknown); hypothetical protein complement(333881..334123) Rickettsia akari str. Hartford 5645613 YP_001493178.1 CDS A1C_01795 NC_009881.1 334178 335395 D COG1022 Long-chain acyl-CoA synthetases (AMP-forming); hypothetical protein 334178..335395 Rickettsia akari str. Hartford 5645614 YP_001493179.1 CDS murC NC_009881.1 335513 336949 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 335513..336949 Rickettsia akari str. Hartford 5645117 YP_001493180.1 CDS murB NC_009881.1 336996 337883 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 336996..337883 Rickettsia akari str. Hartford 5645118 YP_001493181.1 CDS ddl NC_009881.1 338040 339002 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 338040..339002 Rickettsia akari str. Hartford 5645119 YP_001493182.1 CDS A1C_01815 NC_009881.1 339592 339801 D COG1589 Cell division septal protein; cell division protein FtsQ 339592..339801 Rickettsia akari str. Hartford 5645120 YP_001493183.1 CDS A1C_01820 NC_009881.1 339950 341185 D COG0849 Actin-like ATPase involved in cell division; cell division protein FtsA 339950..341185 Rickettsia akari str. Hartford 5645121 YP_001493184.1 CDS A1C_01825 NC_009881.1 341116 341310 R hypothetical protein complement(341116..341310) Rickettsia akari str. Hartford 5645122 YP_001493185.1 CDS A1C_01830 NC_009881.1 341543 341710 R hypothetical protein complement(341543..341710) Rickettsia akari str. Hartford 5645123 YP_001493186.1 CDS A1C_01835 NC_009881.1 342230 342556 R COG1585 Membrane protein implicated in regulation of membrane protease activity; hypothetical protein complement(342230..342556) Rickettsia akari str. Hartford 5645201 YP_001493187.1 CDS A1C_01840 NC_009881.1 342546 343073 R COG3474 Cytochrome c2; cytochrome c complement(342546..343073) Rickettsia akari str. Hartford 5645202 YP_001493188.1 CDS A1C_01845 NC_009881.1 343187 344257 D hypothetical protein 343187..344257 Rickettsia akari str. Hartford 5645203 YP_001493189.1 CDS lpxC NC_009881.1 344266 345132 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(344266..345132) Rickettsia akari str. Hartford 5645204 YP_001493190.1 CDS A1C_01855 NC_009881.1 345385 346533 R hypothetical protein complement(345385..346533) Rickettsia akari str. Hartford 5645205 YP_001493191.1 CDS A1C_01860 NC_009881.1 346962 349034 D COG1530 Ribonucleases G and E; ribonuclease E 346962..349034 Rickettsia akari str. Hartford 5645206 YP_001493192.1 CDS A1C_01865 NC_009881.1 349210 350166 D COG1612 Uncharacterized protein required for cytochrome oxidase assembly; cytochrome c oxidase assembly protein 349210..350166 Rickettsia akari str. Hartford 5645207 YP_001493193.1 CDS A1C_01870 NC_009881.1 350364 351275 D COG0564 Pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase C 350364..351275 Rickettsia akari str. Hartford 5645033 YP_001493194.1 CDS A1C_01875 NC_009881.1 351424 352617 D COG1680 Beta-lactamase class C and other penicillin binding proteins; penicillin-binding protein 4* 351424..352617 Rickettsia akari str. Hartford 5645034 YP_001493195.1 CDS A1C_01880 NC_009881.1 352631 353464 D COG0708 Exonuclease III; exodeoxyribonuclease III 352631..353464 Rickettsia akari str. Hartford 5645035 YP_001493196.1 CDS A1C_01885 NC_009881.1 353506 354486 D COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; pyruvate dehydrogenase e1 component subunit alpha 353506..354486 Rickettsia akari str. Hartford 5645036 YP_001493197.1 CDS A1C_01890 NC_009881.1 354594 355574 D catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 354594..355574 Rickettsia akari str. Hartford 5645037 YP_001493198.1 CDS A1C_01895 NC_009881.1 355762 357591 R COG1217 Predicted membrane GTPase involved in stress response; GTP-binding protein TypA complement(355762..357591) Rickettsia akari str. Hartford 5645038 YP_001493199.1 CDS A1C_01900 NC_009881.1 357791 357955 D hypothetical protein 357791..357955 Rickettsia akari str. Hartford 5645039 YP_001493200.1 CDS A1C_01905 NC_009881.1 357948 358127 D hypothetical protein 357948..358127 Rickettsia akari str. Hartford 5645151 YP_001493201.1 CDS A1C_01910 NC_009881.1 358096 358377 D hypothetical protein 358096..358377 Rickettsia akari str. Hartford 5645152 YP_001493202.1 CDS A1C_01915 NC_009881.1 358789 359295 D COG2825 Outer membrane protein; hypothetical protein 358789..359295 Rickettsia akari str. Hartford 5645153 YP_001493203.1 CDS A1C_01920 NC_009881.1 359376 360827 D catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 359376..360827 Rickettsia akari str. Hartford 5645154 YP_001493204.1 CDS A1C_01925 NC_009881.1 360985 361329 D subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G 360985..361329 Rickettsia akari str. Hartford 5645155 YP_001493205.1 CDS A1C_01930 NC_009881.1 361364 362410 D subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 361364..362410 Rickettsia akari str. Hartford 5645156 YP_001493206.1 CDS A1C_01935 NC_009881.1 362533 363171 D Heme exporter protein B 362533..363171 Rickettsia akari str. Hartford 5645157 YP_001493207.1 CDS A1C_01940 NC_009881.1 363248 363706 D hypothetical protein 363248..363706 Rickettsia akari str. Hartford 5645110 YP_001493208.1 CDS A1C_01945 NC_009881.1 363728 364261 D COG0723 Rieske Fe-S protein; ubiquinol-cytochrome c reductase, iron-sulfur subunit 363728..364261 Rickettsia akari str. Hartford 5645111 YP_001493209.1 CDS A1C_01950 NC_009881.1 364268 365611 D COG1290 Cytochrome b subunit of the bc complex; cytochrome b 364268..365611 Rickettsia akari str. Hartford 5645112 YP_001493210.1 CDS A1C_01955 NC_009881.1 365813 366568 D COG2857 Cytochrome c1; cytochrome c1, heme protein 365813..366568 Rickettsia akari str. Hartford 5645113 YP_001493211.1 CDS A1C_01960 NC_009881.1 366881 367054 D hypothetical protein 366881..367054 Rickettsia akari str. Hartford 5645114 YP_001493212.1 CDS A1C_01965 NC_009881.1 367381 367872 D COG0071 Molecular chaperone (small heat shock protein); heat shock protein 367381..367872 Rickettsia akari str. Hartford 5645115 YP_001493213.1 CDS prfB NC_009881.1 368895 369752 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(368895..369752) Rickettsia akari str. Hartford 5645116 YP_001493214.1 CDS A1C_01975 NC_009881.1 370172 371974 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 370172..371974 Rickettsia akari str. Hartford 5645531 YP_001493215.1 CDS A1C_01980 NC_009881.1 372474 372656 D putative phage-like protein 372474..372656 Rickettsia akari str. Hartford 5645533 YP_001493216.1 CDS A1C_01985 NC_009881.1 372781 372936 R COG3093 Plasmid maintenance system antidote protein; hypothetical protein complement(372781..372936) Rickettsia akari str. Hartford 5645534 YP_001493217.1 CDS A1C_01990 NC_009881.1 373019 373216 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 373019..373216 Rickettsia akari str. Hartford 5645535 YP_001493218.1 CDS A1C_01995 NC_009881.1 373251 374351 R COG0772 Bacterial cell division membrane protein; rod shape-determining protein RodA complement(373251..374351) Rickettsia akari str. Hartford 5645536 YP_001493219.1 CDS A1C_02000 NC_009881.1 374457 376511 R COG1770 Protease II; protease II complement(374457..376511) Rickettsia akari str. Hartford 5645651 YP_001493220.1 CDS A1C_02005 NC_009881.1 376543 378075 R subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D complement(376543..378075) Rickettsia akari str. Hartford 5645652 YP_001493221.1 CDS A1C_02010 NC_009881.1 378077 378271 R toxin of toxin-antitoxin system VapC complement(378077..378271) Rickettsia akari str. Hartford 5645653 YP_001493222.1 CDS A1C_02015 NC_009881.1 378813 380276 R subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D complement(378813..380276) Rickettsia akari str. Hartford 5645654 YP_001493223.1 CDS A1C_02020 NC_009881.1 380191 380295 D putative monovalent cation/H+ antiporter subunit D 380191..380295 Rickettsia akari str. Hartford 5645655 YP_001493224.1 CDS A1C_02025 NC_009881.1 380497 381597 R subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D complement(380497..381597) Rickettsia akari str. Hartford 5645656 YP_001493225.1 CDS A1C_02030 NC_009881.1 381653 381796 D putative monovalent cation/H+ antiporter subunit C 381653..381796 Rickettsia akari str. Hartford 5645657 YP_001493226.1 CDS A1C_02035 NC_009881.1 381780 382115 R subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C complement(381780..382115) Rickettsia akari str. Hartford 5645403 YP_001493227.1 CDS A1C_02040 NC_009881.1 382294 383046 R COG3504 Type IV secretory pathway, VirB9 components; VirB9 protein complement(382294..383046) Rickettsia akari str. Hartford 5645404 YP_001493228.1 CDS A1C_02045 NC_009881.1 383048 383746 R COG3736 Type IV secretory pathway, component VirB8; VirB8 protein complement(383048..383746) Rickettsia akari str. Hartford 5645405 YP_001493229.1 CDS A1C_02050 NC_009881.1 384210 384389 D hypothetical protein 384210..384389 Rickettsia akari str. Hartford 5645406 YP_001493230.1 CDS A1C_02055 NC_009881.1 384440 385171 D COG3736 Type IV secretory pathway, component VirB8; VirB8 protein 384440..385171 Rickettsia akari str. Hartford 5645407 YP_001493231.1 CDS A1C_02060 NC_009881.1 385158 385634 D COG3504 Type IV secretory pathway, VirB9 components; VirB9 protein precursor 385158..385634 Rickettsia akari str. Hartford 5645408 YP_001493232.1 CDS A1C_02065 NC_009881.1 385779 387233 D COG2948 Type IV secretory pathway, VirB10 components; virB10 protein 385779..387233 Rickettsia akari str. Hartford 5645409 YP_001493233.1 CDS A1C_02070 NC_009881.1 387230 388234 D COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis; type IV secretion system ATPase VirB11 387230..388234 Rickettsia akari str. Hartford 5645559 YP_001493234.1 CDS A1C_02075 NC_009881.1 388397 390172 D COG3505 Type IV secretory pathway, VirD4 components; type IV secretion system protein VirB8 388397..390172 Rickettsia akari str. Hartford 5645560 YP_001493235.1 CDS A1C_02080 NC_009881.1 390182 391594 D COG0248 Exopolyphosphatase; guanosine pentaphosphate phosphohydrolase 390182..391594 Rickettsia akari str. Hartford 5645561 YP_001493236.1 CDS A1C_02105 NC_009881.1 393376 393597 D cell surface antigen-like protein Sca7 393376..393597 Rickettsia akari str. Hartford 5645562 YP_001493237.1 CDS A1C_02110 NC_009881.1 393606 393824 D cell surface antigen-like protein Sca7 393606..393824 Rickettsia akari str. Hartford 5645563 YP_001493238.1 CDS A1C_02115 NC_009881.1 393836 394366 D cell surface antigen-like protein Sca7 393836..394366 Rickettsia akari str. Hartford 5645564 YP_001493239.1 CDS A1C_02120 NC_009881.1 394596 394814 D cell surface antigen-like protein Sca7 394596..394814 Rickettsia akari str. Hartford 5645565 YP_001493240.1 CDS A1C_02125 NC_009881.1 394811 394873 D hypothetical protein 394811..394873 Rickettsia akari str. Hartford 5645694 YP_001493241.1 CDS A1C_02130 NC_009881.1 395226 395540 D protein transport protein sec7 (sec7) 395226..395540 Rickettsia akari str. Hartford 5645695 YP_001493242.1 CDS A1C_02135 NC_009881.1 395825 396022 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 395825..396022 Rickettsia akari str. Hartford 5645696 YP_001493243.1 CDS A1C_02140 NC_009881.1 396033 396242 D cell surface antigen-like protein Sca7 396033..396242 Rickettsia akari str. Hartford 5645697 YP_001493244.1 CDS A1C_02145 NC_009881.1 396274 396501 D cell surface antigen-like protein Sca7 396274..396501 Rickettsia akari str. Hartford 5645698 YP_001493245.1 CDS A1C_02150 NC_009881.1 396501 397385 D cell surface antigen Sca3 396501..397385 Rickettsia akari str. Hartford 5645699 YP_001493246.1 CDS A1C_02155 NC_009881.1 397382 397600 R hypothetical protein complement(397382..397600) Rickettsia akari str. Hartford 5645700 YP_001493247.1 CDS A1C_02160 NC_009881.1 398228 398338 D transposase 398228..398338 Rickettsia akari str. Hartford 5645701 YP_001493248.1 CDS A1C_02165 NC_009881.1 398406 398684 D transposase 398406..398684 Rickettsia akari str. Hartford 5645238 YP_001493249.1 CDS A1C_02180 NC_009881.1 400901 401062 R hypothetical protein complement(400901..401062) Rickettsia akari str. Hartford 5645239 YP_001493250.1 CDS A1C_02185 NC_009881.1 401064 401297 R hypothetical protein complement(401064..401297) Rickettsia akari str. Hartford 5645240 YP_001493251.1 CDS A1C_02190 NC_009881.1 401496 401744 R hypothetical protein complement(401496..401744) Rickettsia akari str. Hartford 5645241 YP_001493252.1 CDS A1C_02195 NC_009881.1 401964 402851 D hypothetical protein 401964..402851 Rickettsia akari str. Hartford 5645242 YP_001493253.1 CDS A1C_02200 NC_009881.1 402835 403680 D hypothetical protein 402835..403680 Rickettsia akari str. Hartford 5645243 YP_001493254.1 CDS A1C_02205 NC_009881.1 403977 404756 D COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; cysQ protein 403977..404756 Rickettsia akari str. Hartford 5645244 YP_001493255.1 CDS A1C_02210 NC_009881.1 404869 407529 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(404869..407529) Rickettsia akari str. Hartford 5644692 YP_001493256.1 CDS A1C_02215 NC_009881.1 408062 408226 D hypothetical protein 408062..408226 Rickettsia akari str. Hartford 5644693 YP_001493257.1 CDS A1C_02230 NC_009881.1 409553 409987 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B complement(409553..409987) Rickettsia akari str. Hartford 5644694 YP_001493258.1 CDS A1C_02235 NC_009881.1 410030 410707 D COG0739 Membrane proteins related to metalloendopeptidases; metalloendopeptidase-like membrane protein 410030..410707 Rickettsia akari str. Hartford 5644695 YP_001493259.1 CDS A1C_02250 NC_009881.1 411429 411554 D COG2161 Antitoxin of toxin-antitoxin stability system; antitoxin of toxin-antitoxin stability system 411429..411554 Rickettsia akari str. Hartford 5644696 YP_001493260.1 CDS A1C_02255 NC_009881.1 411695 411853 D COG4115 Uncharacterized protein conserved in bacteria; toxin of toxin-antitoxin system 411695..411853 Rickettsia akari str. Hartford 5644697 YP_001493261.1 CDS thyX NC_009881.1 411948 412832 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 411948..412832 Rickettsia akari str. Hartford 5644698 YP_001493262.1 CDS tolB NC_009881.1 412988 414322 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 412988..414322 Rickettsia akari str. Hartford 5645460 YP_001493263.1 CDS A1C_02270 NC_009881.1 414458 415339 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(414458..415339) Rickettsia akari str. Hartford 5645461 YP_001493264.1 CDS A1C_02275 NC_009881.1 415425 415970 D involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 415425..415970 Rickettsia akari str. Hartford 5645462 YP_001493265.1 CDS A1C_02280 NC_009881.1 416183 417160 R hypothetical protein complement(416183..417160) Rickettsia akari str. Hartford 5645463 YP_001493266.1 CDS mnmA NC_009881.1 417410 418507 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 417410..418507 Rickettsia akari str. Hartford 5645464 YP_001493267.1 CDS A1C_02290 NC_009881.1 418585 419976 D COG0531 Amino acid transporters; cationic amino acid transporter-1 418585..419976 Rickettsia akari str. Hartford 5645465 YP_001493268.1 CDS hisS NC_009881.1 420129 421376 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 420129..421376 Rickettsia akari str. Hartford 5645466 YP_001493269.1 CDS A1C_02300 NC_009881.1 421440 421802 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 421440..421802 Rickettsia akari str. Hartford 5645601 YP_001493270.1 CDS A1C_02305 NC_009881.1 421888 422103 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 421888..422103 Rickettsia akari str. Hartford 5645602 YP_001493271.1 CDS A1C_02310 NC_009881.1 423131 423856 D COG0811 Biopolymer transport proteins; TolQ protein 423131..423856 Rickettsia akari str. Hartford 5645603 YP_001493272.1 CDS A1C_02315 NC_009881.1 423856 424287 D COG0848 Biopolymer transport protein; TolR protein 423856..424287 Rickettsia akari str. Hartford 5645604 YP_001493273.1 CDS A1C_02320 NC_009881.1 424277 425257 D periplasmic protein TonB 424277..425257 Rickettsia akari str. Hartford 5645605 YP_001493274.1 CDS A1C_02325 NC_009881.1 425757 426134 R COG1266 Predicted metal-dependent membrane protease; hypothetical protein complement(425757..426134) Rickettsia akari str. Hartford 5645606 YP_001493275.1 CDS A1C_02330 NC_009881.1 426823 427317 D COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein 426823..427317 Rickettsia akari str. Hartford 5645607 YP_001493276.1 CDS A1C_02335 NC_009881.1 427268 428641 R COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter complement(427268..428641) Rickettsia akari str. Hartford 5645216 YP_001493277.1 CDS A1C_02340 NC_009881.1 428725 430260 R COG0845 Membrane-fusion protein; alkaline protease secretion protein AprE complement(428725..430260) Rickettsia akari str. Hartford 5645217 YP_001493278.1 CDS A1C_02345 NC_009881.1 430457 432235 R COG4618 ABC-type protease/lipase transport system, ATPase and permease components; alkaline protease secretion ATP-binding protein AprD complement(430457..432235) Rickettsia akari str. Hartford 5645218 YP_001493279.1 CDS A1C_02350 NC_009881.1 432222 433238 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(432222..433238) Rickettsia akari str. Hartford 5645219 YP_001493280.1 CDS A1C_02355 NC_009881.1 433231 433593 R COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; protein kinase C inhibitor 1 complement(433231..433593) Rickettsia akari str. Hartford 5645220 YP_001493281.1 CDS A1C_02360 NC_009881.1 433818 434051 R hypothetical protein complement(433818..434051) Rickettsia akari str. Hartford 5645221 YP_001493282.1 CDS A1C_02365 NC_009881.1 434562 435110 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 434562..435110 Rickettsia akari str. Hartford 5645222 YP_001493283.1 CDS hslU NC_009881.1 435107 436459 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 435107..436459 Rickettsia akari str. Hartford 5645789 YP_001493284.1 CDS lpxB NC_009881.1 436652 436720 D lipid-A-disaccharide synthase 436652..436720 Rickettsia akari str. Hartford 5645790 YP_001493285.1 CDS lpxB NC_009881.1 436733 437908 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 436733..437908 Rickettsia akari str. Hartford 5645791 YP_001493286.1 CDS A1C_02385 NC_009881.1 437888 438169 R hypothetical protein complement(437888..438169) Rickettsia akari str. Hartford 5645792 YP_001493287.1 CDS A1C_02390 NC_009881.1 438485 439534 D COG1559 Predicted periplasmic solute-binding protein; hypothetical protein 438485..439534 Rickettsia akari str. Hartford 5645793 YP_001493288.1 CDS cyaY NC_009881.1 439581 439886 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 439581..439886 Rickettsia akari str. Hartford 5645794 YP_001493289.1 CDS A1C_02410 NC_009881.1 440370 440480 D hypothetical protein 440370..440480 Rickettsia akari str. Hartford 5645795 YP_001493290.1 CDS A1C_02415 NC_009881.1 440495 440623 D hypothetical protein 440495..440623 Rickettsia akari str. Hartford 5645144 YP_001493291.1 CDS A1C_02420 NC_009881.1 440670 440873 D hypothetical protein 440670..440873 Rickettsia akari str. Hartford 5645145 YP_001493292.1 CDS A1C_02425 NC_009881.1 441000 441077 D hypothetical protein 441000..441077 Rickettsia akari str. Hartford 5645146 YP_001493293.1 CDS A1C_02430 NC_009881.1 441362 441742 D hypothetical protein 441362..441742 Rickettsia akari str. Hartford 5645147 YP_001493294.1 CDS gltX NC_009881.1 441926 443269 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(441926..443269) Rickettsia akari str. Hartford 5645148 YP_001493295.1 CDS A1C_02440 NC_009881.1 443524 445854 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(443524..445854) Rickettsia akari str. Hartford 5645149 YP_001493296.1 CDS A1C_02445 NC_009881.1 445978 446172 R hypothetical protein complement(445978..446172) Rickettsia akari str. Hartford 5645150 YP_001493297.1 CDS A1C_02450 NC_009881.1 446634 446957 R putative DNA processing protein DprA complement(446634..446957) Rickettsia akari str. Hartford 5645410 YP_001493298.1 CDS A1C_02455 NC_009881.1 447151 447753 R COG0450 Peroxiredoxin; thioredoxin peroxidase 1 complement(447151..447753) Rickettsia akari str. Hartford 5645411 YP_001493299.1 CDS A1C_02460 NC_009881.1 447835 448770 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; membrane protease subunit stomatin/prohibitin-like protein complement(447835..448770) Rickettsia akari str. Hartford 5645412 YP_001493300.1 CDS A1C_02465 NC_009881.1 449549 451117 R COG2194 Predicted membrane-associated, metal-dependent hydrolase; hypothetical protein complement(449549..451117) Rickettsia akari str. Hartford 5645413 YP_001493301.1 CDS A1C_02470 NC_009881.1 451193 451657 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 451193..451657 Rickettsia akari str. Hartford 5645414 YP_001493302.1 CDS A1C_02475 NC_009881.1 451872 452057 D COG3093 Plasmid maintenance system antidote protein; plasmid maintenance system antidote protein 451872..452057 Rickettsia akari str. Hartford 5645415 YP_001493303.1 CDS A1C_02480 NC_009881.1 452296 453150 D COG1091 dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 452296..453150 Rickettsia akari str. Hartford 5645416 YP_001493304.1 CDS A1C_02485 NC_009881.1 453327 454352 D COG1086 Predicted nucleoside-diphosphate sugar epimerases; CapD protein 453327..454352 Rickettsia akari str. Hartford 5645868 YP_001493305.1 CDS A1C_02490 NC_009881.1 454345 455604 D COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 454345..455604 Rickettsia akari str. Hartford 5645869 YP_001493306.1 CDS A1C_02495 NC_009881.1 455633 456907 D hypothetical protein 455633..456907 Rickettsia akari str. Hartford 5645870 YP_001493307.1 CDS A1C_02500 NC_009881.1 456926 457111 D hypothetical protein 456926..457111 Rickettsia akari str. Hartford 5645871 YP_001493308.1 CDS A1C_02505 NC_009881.1 457124 457387 D hypothetical protein 457124..457387 Rickettsia akari str. Hartford 5645872 YP_001493309.1 CDS A1C_02510 NC_009881.1 458015 459829 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 458015..459829 Rickettsia akari str. Hartford 5645873 YP_001493310.1 CDS A1C_02525 NC_009881.1 460889 461656 R hypothetical protein complement(460889..461656) Rickettsia akari str. Hartford 5645874 YP_001493311.1 CDS A1C_02530 NC_009881.1 461926 462687 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein complement(461926..462687) Rickettsia akari str. Hartford 5644649 YP_001493312.1 CDS A1C_02535 NC_009881.1 462720 463892 D COG0438 Glycosyltransferase; glycosyltransferase 462720..463892 Rickettsia akari str. Hartford 5644650 YP_001493313.1 CDS A1C_02540 NC_009881.1 463954 464151 R COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter ATP-binding protein complement(463954..464151) Rickettsia akari str. Hartford 5644651 YP_001493314.1 CDS A1C_02545 NC_009881.1 464313 464627 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; hypothetical protein complement(464313..464627) Rickettsia akari str. Hartford 5644652 YP_001493315.1 CDS A1C_02550 NC_009881.1 464790 465086 R hypothetical protein complement(464790..465086) Rickettsia akari str. Hartford 5644653 YP_001493316.1 CDS A1C_02555 NC_009881.1 465117 465290 R ABC transporter ATP-binding protein complement(465117..465290) Rickettsia akari str. Hartford 5644654 YP_001493317.1 CDS rpsD NC_009881.1 465760 466026 R 30S ribosomal protein S4 complement(465760..466026) Rickettsia akari str. Hartford 5644655 YP_001493318.1 CDS rpsD NC_009881.1 466268 466885 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(466268..466885) Rickettsia akari str. Hartford 5645165 YP_001493319.1 CDS A1C_02570 NC_009881.1 467004 467921 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 467004..467921 Rickettsia akari str. Hartford 5645166 YP_001493320.1 CDS A1C_02575 NC_009881.1 468248 468667 R COG1533 DNA repair photolyase; putative lyase complement(468248..468667) Rickettsia akari str. Hartford 5645167 YP_001493321.1 CDS A1C_02580 NC_009881.1 468719 468847 R putative lyase complement(468719..468847) Rickettsia akari str. Hartford 5645168 YP_001493322.1 CDS A1C_02585 NC_009881.1 469091 469471 D hypothetical protein 469091..469471 Rickettsia akari str. Hartford 5645169 YP_001493323.1 CDS A1C_02590 NC_009881.1 469453 469566 D hypothetical protein 469453..469566 Rickettsia akari str. Hartford 5645170 YP_001493324.1 CDS A1C_02595 NC_009881.1 470014 470157 D hypothetical protein 470014..470157 Rickettsia akari str. Hartford 5645171 YP_001493325.1 CDS A1C_02600 NC_009881.1 470445 472937 R COG2982 Uncharacterized protein involved in outer membrane biogenesis; outer membrane assembly protein complement(470445..472937) Rickettsia akari str. Hartford 5645644 YP_001493326.1 CDS A1C_02605 NC_009881.1 473317 473514 D transposase 473317..473514 Rickettsia akari str. Hartford 5645645 YP_001493327.1 CDS rimM NC_009881.1 473536 474033 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(473536..474033) Rickettsia akari str. Hartford 5645646 YP_001493328.1 CDS A1C_02625 NC_009881.1 476738 476980 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 476738..476980 Rickettsia akari str. Hartford 5645647 YP_001493329.1 CDS A1C_02630 NC_009881.1 477518 477718 D hypothetical protein 477518..477718 Rickettsia akari str. Hartford 5645648 YP_001493330.1 CDS A1C_02635 NC_009881.1 478114 478488 R COG2094 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase complement(478114..478488) Rickettsia akari str. Hartford 5645649 YP_001493331.1 CDS A1C_02640 NC_009881.1 479020 479268 R COG0759 Uncharacterized conserved protein; hypothetical protein complement(479020..479268) Rickettsia akari str. Hartford 5645650 YP_001493332.1 CDS A1C_02645 NC_009881.1 479261 479764 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(479261..479764) Rickettsia akari str. Hartford 5644977 YP_001493333.1 CDS A1C_02650 NC_009881.1 479801 480985 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D complement(479801..480985) Rickettsia akari str. Hartford 5644978 YP_001493334.1 CDS A1C_02655 NC_009881.1 481064 481210 R COG2827 Predicted endonuclease containing a URI domain; endo/excinuclease amino terminal domain-containing protein complement(481064..481210) Rickettsia akari str. Hartford 5644979 YP_001493335.1 CDS A1C_02660 NC_009881.1 481210 481332 R COG2827 Predicted endonuclease containing a URI domain; NADH dehydrogenase subunit C complement(481210..481332) Rickettsia akari str. Hartford 5644980 YP_001493336.1 CDS A1C_02665 NC_009881.1 481414 482037 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C complement(481414..482037) Rickettsia akari str. Hartford 5644981 YP_001493337.1 CDS A1C_02670 NC_009881.1 482015 482539 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(482015..482539) Rickettsia akari str. Hartford 5644982 YP_001493338.1 CDS A1C_02675 NC_009881.1 482542 482913 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(482542..482913) Rickettsia akari str. Hartford 5644983 YP_001493339.1 CDS A1C_02680 NC_009881.1 483013 484239 R COG3307 Lipid A core - O-antigen ligase and related enzymes; hypothetical protein complement(483013..484239) Rickettsia akari str. Hartford 5645249 YP_001493340.1 CDS A1C_02685 NC_009881.1 484236 484718 R COG4765 Uncharacterized protein conserved in bacteria; hypothetical protein complement(484236..484718) Rickettsia akari str. Hartford 5645250 YP_001493341.1 CDS A1C_02690 NC_009881.1 484894 485184 D COG5410 Uncharacterized protein conserved in bacteria; hypothetical protein 484894..485184 Rickettsia akari str. Hartford 5645251 YP_001493342.1 CDS A1C_02695 NC_009881.1 485337 485435 D hypothetical protein 485337..485435 Rickettsia akari str. Hartford 5645252 YP_001493343.1 CDS A1C_02700 NC_009881.1 485768 485920 D hypothetical protein 485768..485920 Rickettsia akari str. Hartford 5645253 YP_001493344.1 CDS xerD NC_009881.1 486550 487470 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 486550..487470 Rickettsia akari str. Hartford 5645255 YP_001493345.1 CDS A1C_02710 NC_009881.1 487553 488614 D hypothetical protein 487553..488614 Rickettsia akari str. Hartford 5645518 YP_001493346.1 CDS A1C_02715 NC_009881.1 488726 489889 D hypothetical protein 488726..489889 Rickettsia akari str. Hartford 5645519 YP_001493347.1 CDS A1C_02720 NC_009881.1 490076 490858 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(490076..490858) Rickettsia akari str. Hartford 5645520 YP_001493348.1 CDS lnt NC_009881.1 490941 492431 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 490941..492431 Rickettsia akari str. Hartford 5645521 YP_001493349.1 CDS A1C_02730 NC_009881.1 494104 495021 D COG2984 ABC-type uncharacterized transport system, periplasmic component; hypothetical protein 494104..495021 Rickettsia akari str. Hartford 5645522 YP_001493350.1 CDS A1C_02735 NC_009881.1 495026 495859 D COG4120 ABC-type uncharacterized transport system, permease component; ABC transporter permease 495026..495859 Rickettsia akari str. Hartford 5645523 YP_001493351.1 CDS A1C_02740 NC_009881.1 495976 496719 D COG1101 ABC-type uncharacterized transport system, ATPase component; putative ABC transporter ATP-binding protein 495976..496719 Rickettsia akari str. Hartford 5645730 YP_001493352.1 CDS A1C_02745 NC_009881.1 496721 497020 R transposase IS982 complement(496721..497020) Rickettsia akari str. Hartford 5645731 YP_001493353.1 CDS A1C_02750 NC_009881.1 497779 498294 R COG1495 Disulfide bond formation protein DsbB; hypothetical protein complement(497779..498294) Rickettsia akari str. Hartford 5645732 YP_001493354.1 CDS lysK NC_009881.1 498497 500086 D class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 498497..500086 Rickettsia akari str. Hartford 5645733 YP_001493355.1 CDS A1C_02760 NC_009881.1 500147 501079 D COG0679 Predicted permeases; permease 500147..501079 Rickettsia akari str. Hartford 5645734 YP_001493356.1 CDS A1C_02765 NC_009881.1 501203 503506 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 501203..503506 Rickettsia akari str. Hartford 5645735 YP_001493357.1 CDS A1C_02770 NC_009881.1 503767 505716 D COG5307 SEC7 domain proteins; hypothetical protein 503767..505716 Rickettsia akari str. Hartford 5645736 YP_001493358.1 CDS A1C_02775 NC_009881.1 506001 506198 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 506001..506198 Rickettsia akari str. Hartford 5644883 YP_001493359.1 CDS A1C_02780 NC_009881.1 506229 506444 R COG4374 Uncharacterized protein conserved in bacteria; hypothetical protein complement(506229..506444) Rickettsia akari str. Hartford 5644884 YP_001493360.1 CDS A1C_02785 NC_009881.1 506437 506568 R hypothetical protein complement(506437..506568) Rickettsia akari str. Hartford 5644885 YP_001493361.1 CDS A1C_02790 NC_009881.1 506561 506857 R hypothetical protein complement(506561..506857) Rickettsia akari str. Hartford 5644886 YP_001493362.1 CDS A1C_02795 NC_009881.1 506954 508285 D COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter 506954..508285 Rickettsia akari str. Hartford 5644887 YP_001493363.1 CDS A1C_02800 NC_009881.1 508784 509023 R hypothetical protein complement(508784..509023) Rickettsia akari str. Hartford 5644888 YP_001493364.1 CDS A1C_02805 NC_009881.1 509120 509302 R hypothetical protein complement(509120..509302) Rickettsia akari str. Hartford 5644889 YP_001493365.1 CDS A1C_02825 NC_009881.1 511645 512589 R Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase complement(511645..512589) Rickettsia akari str. Hartford 5644635 YP_001493366.1 CDS A1C_02830 NC_009881.1 513830 515353 R COG3202 ATP/ADP translocase; ADP,ATP carrier protein complement(513830..515353) Rickettsia akari str. Hartford 5644636 YP_001493367.1 CDS A1C_02835 NC_009881.1 515287 515460 R CTP synthetase complement(515287..515460) Rickettsia akari str. Hartford 5644637 YP_001493368.1 CDS A1C_02845 NC_009881.1 516093 516260 D CTP synthetase 516093..516260 Rickettsia akari str. Hartford 5644638 YP_001493369.1 CDS A1C_02855 NC_009881.1 517215 517955 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(517215..517955) Rickettsia akari str. Hartford 5644639 YP_001493370.1 CDS A1C_02860 NC_009881.1 518463 518666 R COG1051 ADP-ribose pyrophosphatase; ADP-ribose pyrophosphatase MutT complement(518463..518666) Rickettsia akari str. Hartford 5645825 YP_001493371.1 CDS A1C_02865 NC_009881.1 518880 520430 D hypothetical protein 518880..520430 Rickettsia akari str. Hartford 5645826 YP_001493372.1 CDS folE NC_009881.1 520423 520995 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 520423..520995 Rickettsia akari str. Hartford 5645827 YP_001493373.1 CDS A1C_02875 NC_009881.1 521006 522289 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 521006..522289 Rickettsia akari str. Hartford 5645828 YP_001493374.1 CDS A1C_02880 NC_009881.1 522339 522566 D antitoxin of toxin-antitoxin system StbD 522339..522566 Rickettsia akari str. Hartford 5645829 YP_001493375.1 CDS A1C_02885 NC_009881.1 522566 522670 D hypothetical protein 522566..522670 Rickettsia akari str. Hartford 5645775 YP_001493376.1 CDS A1C_02890 NC_009881.1 522907 523122 D hypothetical protein 522907..523122 Rickettsia akari str. Hartford 5645776 YP_001493377.1 CDS ruvA NC_009881.1 523128 523739 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 523128..523739 Rickettsia akari str. Hartford 5645777 YP_001493378.1 CDS A1C_02900 NC_009881.1 523726 523860 D hypothetical protein 523726..523860 Rickettsia akari str. Hartford 5645778 YP_001493379.1 CDS A1C_02905 NC_009881.1 524058 524276 D hypothetical protein 524058..524276 Rickettsia akari str. Hartford 5645779 YP_001493380.1 CDS ruvB NC_009881.1 524339 525367 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 524339..525367 Rickettsia akari str. Hartford 5645780 YP_001493381.1 CDS A1C_02915 NC_009881.1 525360 527123 D COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein 525360..527123 Rickettsia akari str. Hartford 5645781 YP_001493382.1 CDS A1C_02920 NC_009881.1 527474 528718 D COG0477 Permeases of the major facilitator superfamily; AmpG protein 527474..528718 Rickettsia akari str. Hartford 5645782 YP_001493383.1 CDS A1C_02925 NC_009881.1 528910 529830 D COG1686 D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein dacF 528910..529830 Rickettsia akari str. Hartford 5645082 YP_001493384.1 CDS A1C_02930 NC_009881.1 530156 530854 R COG0797 Lipoproteins; rare lipoprotein A complement(530156..530854) Rickettsia akari str. Hartford 5645083 YP_001493385.1 CDS A1C_02935 NC_009881.1 530832 531446 R COG2823 Predicted periplasmic or secreted lipoprotein; hypothetical protein complement(530832..531446) Rickettsia akari str. Hartford 5645084 YP_001493386.1 CDS A1C_02940 NC_009881.1 531856 532398 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(531856..532398) Rickettsia akari str. Hartford 5645085 YP_001493387.1 CDS A1C_02945 NC_009881.1 532428 533276 R COG0672 High-affinity Fe2+/Pb2+ permease; FTR1 family protein complement(532428..533276) Rickettsia akari str. Hartford 5645086 YP_001493388.1 CDS A1C_02950 NC_009881.1 533286 533666 R hypothetical protein complement(533286..533666) Rickettsia akari str. Hartford 5645087 YP_001493389.1 CDS A1C_02955 NC_009881.1 533775 533888 R hypothetical protein complement(533775..533888) Rickettsia akari str. Hartford 5645088 YP_001493390.1 CDS A1C_02960 NC_009881.1 533895 534890 R COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; hypothetical protein complement(533895..534890) Rickettsia akari str. Hartford 5645380 YP_001493391.1 CDS A1C_02965 NC_009881.1 535202 535828 D COG3485 Protocatechuate 3,4-dioxygenase beta subunit; protocatechuate-3,4-dioxygenase subunit beta 535202..535828 Rickettsia akari str. Hartford 5645381 YP_001493392.1 CDS A1C_02970 NC_009881.1 536003 536668 D COG0526 Thiol-disulfide isomerase and thioredoxins; thiol:disulfide interchange protein tlpA 536003..536668 Rickettsia akari str. Hartford 5645382 YP_001493393.1 CDS A1C_02975 NC_009881.1 536661 537575 D COG0616 Periplasmic serine proteases (ClpP class); signal peptide peptidase SppA 536661..537575 Rickettsia akari str. Hartford 5645383 YP_001493394.1 CDS dut NC_009881.1 537731 538177 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 537731..538177 Rickettsia akari str. Hartford 5645384 YP_001493395.1 CDS A1C_02985 NC_009881.1 538373 540370 D COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); soluble lytic murein transglycosylase precursor 538373..540370 Rickettsia akari str. Hartford 5645385 YP_001493396.1 CDS A1C_02990 NC_009881.1 540450 541631 D hypothetical protein 540450..541631 Rickettsia akari str. Hartford 5645386 YP_001493397.1 CDS A1C_02995 NC_009881.1 541716 542669 D COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; microcin C7 self-immunity protein 541716..542669 Rickettsia akari str. Hartford 5645103 YP_001493398.1 CDS A1C_03000 NC_009881.1 542770 545436 R COG2887 RecB family exonuclease; hypothetical protein complement(542770..545436) Rickettsia akari str. Hartford 5645104 YP_001493399.1 CDS A1C_03005 NC_009881.1 545541 545924 D hypothetical protein 545541..545924 Rickettsia akari str. Hartford 5645105 YP_001493400.1 CDS A1C_03010 NC_009881.1 545982 546710 R COG2071 Predicted glutamine amidotransferases; hypothetical protein complement(545982..546710) Rickettsia akari str. Hartford 5645106 YP_001493401.1 CDS A1C_03015 NC_009881.1 546881 548503 R COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome c oxidase polypeptide I complement(546881..548503) Rickettsia akari str. Hartford 5645107 YP_001493402.1 CDS A1C_03020 NC_009881.1 549021 549203 R hypothetical protein complement(549021..549203) Rickettsia akari str. Hartford 5645108 YP_001493403.1 CDS A1C_03025 NC_009881.1 549200 549334 R hypothetical protein complement(549200..549334) Rickettsia akari str. Hartford 5645109 YP_001493404.1 CDS A1C_03030 NC_009881.1 549578 550519 R COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome c oxidase polypeptide II complement(549578..550519) Rickettsia akari str. Hartford 5645277 YP_001493405.1 CDS A1C_03035 NC_009881.1 551338 552672 D COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 551338..552672 Rickettsia akari str. Hartford 5645278 YP_001493406.1 CDS lspA NC_009881.1 552987 553577 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 552987..553577 Rickettsia akari str. Hartford 5645279 YP_001493407.1 CDS A1C_03045 NC_009881.1 553598 553846 D hypothetical protein 553598..553846 Rickettsia akari str. Hartford 5645280 YP_001493408.1 CDS murD NC_009881.1 553916 555394 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 553916..555394 Rickettsia akari str. Hartford 5645281 YP_001493409.1 CDS A1C_03055 NC_009881.1 555649 556782 D COG0772 Bacterial cell division membrane protein; cell division protein FtsW 555649..556782 Rickettsia akari str. Hartford 5645282 YP_001493410.1 CDS murG NC_009881.1 556779 557927 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 556779..557927 Rickettsia akari str. Hartford 5645283 YP_001493411.1 CDS A1C_03065 NC_009881.1 558128 558784 D hypothetical protein 558128..558784 Rickettsia akari str. Hartford 5645060 YP_001493412.1 CDS A1C_03070 NC_009881.1 559101 559313 D hypothetical protein 559101..559313 Rickettsia akari str. Hartford 5645061 YP_001493413.1 CDS A1C_03095 NC_009881.1 561574 561978 R COG0841 Cation/multidrug efflux pump; RND family efflux transporter complement(561574..561978) Rickettsia akari str. Hartford 5645062 YP_001493414.1 CDS A1C_03100 NC_009881.1 562465 562566 R RND family transporter membrane-fusion protein complement(562465..562566) Rickettsia akari str. Hartford 5645063 YP_001493415.1 CDS A1C_03105 NC_009881.1 562920 563213 R COG0845 Membrane-fusion protein; RND family transporter membrane-fusion protein complement(562920..563213) Rickettsia akari str. Hartford 5645064 YP_001493416.1 CDS A1C_03110 NC_009881.1 563292 563489 R COG0845 Membrane-fusion protein; RND family transporter membrane-fusion protein complement(563292..563489) Rickettsia akari str. Hartford 5645065 YP_001493417.1 CDS A1C_03115 NC_009881.1 563672 564052 R COG1538 Outer membrane protein; hypothetical protein complement(563672..564052) Rickettsia akari str. Hartford 5645066 YP_001493418.1 CDS A1C_03120 NC_009881.1 564528 565550 R COG0438 Glycosyltransferase; glycosyltransferase complement(564528..565550) Rickettsia akari str. Hartford 5644905 YP_001493419.1 CDS A1C_03125 NC_009881.1 565695 566087 R hypothetical protein complement(565695..566087) Rickettsia akari str. Hartford 5644906 YP_001493420.1 CDS dapF NC_009881.1 566521 567333 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 566521..567333 Rickettsia akari str. Hartford 5644907 YP_001493421.1 CDS A1C_03135 NC_009881.1 567323 568573 D COG0621 2-methylthioadenine synthetase; MiaB-like tRNA modifying enzyme 567323..568573 Rickettsia akari str. Hartford 5644908 YP_001493422.1 CDS pheS NC_009881.1 568674 569723 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 568674..569723 Rickettsia akari str. Hartford 5644909 YP_001493423.1 CDS pheT NC_009881.1 569720 572116 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 569720..572116 Rickettsia akari str. Hartford 5644910 YP_001493424.1 CDS A1C_03150 NC_009881.1 572240 573379 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 572240..573379 Rickettsia akari str. Hartford 5644911 YP_001493425.1 CDS A1C_03155 NC_009881.1 573670 574173 D hypothetical protein 573670..574173 Rickettsia akari str. Hartford 5644802 YP_001493426.1 CDS leuS NC_009881.1 574288 576900 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 574288..576900 Rickettsia akari str. Hartford 5644803 YP_001493427.1 CDS A1C_03165 NC_009881.1 577294 577905 R COG0349 Ribonuclease D; ribonuclease D complement(577294..577905) Rickettsia akari str. Hartford 5644804 YP_001493428.1 CDS A1C_03170 NC_009881.1 578038 578361 R COG2919 Septum formation initiator; hypothetical protein complement(578038..578361) Rickettsia akari str. Hartford 5644805 YP_001493429.1 CDS A1C_03175 NC_009881.1 578358 579038 R COG0575 CDP-diglyceride synthetase; phosphatidate cytidylyltransferase complement(578358..579038) Rickettsia akari str. Hartford 5644806 YP_001493430.1 CDS A1C_03180 NC_009881.1 578998 579678 R COG0020 Undecaprenyl pyrophosphate synthase; undecaprenyl pyrophosphate synthetase complement(578998..579678) Rickettsia akari str. Hartford 5644807 YP_001493431.1 CDS A1C_03185 NC_009881.1 579911 581173 R COG0642 Signal transduction histidine kinase; osmolarity sensor protein EnvZ complement(579911..581173) Rickettsia akari str. Hartford 5644808 YP_001493432.1 CDS A1C_03190 NC_009881.1 581314 581994 R COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PetR protein complement(581314..581994) Rickettsia akari str. Hartford 5645629 YP_001493433.1 CDS A1C_03195 NC_009881.1 582134 583006 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 582134..583006 Rickettsia akari str. Hartford 5645630 YP_001493434.1 CDS A1C_03200 NC_009881.1 583124 584008 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 583124..584008 Rickettsia akari str. Hartford 5645631 YP_001493435.1 CDS smpB NC_009881.1 584005 584463 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 584005..584463 Rickettsia akari str. Hartford 5645632 YP_001493436.1 CDS A1C_03210 NC_009881.1 584629 585423 D COG1651 Protein-disulfide isomerase; Thiol:disulfide interchange protein DsbA 584629..585423 Rickettsia akari str. Hartford 5645633 YP_001493437.1 CDS A1C_03215 NC_009881.1 585801 586679 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(585801..586679) Rickettsia akari str. Hartford 5645634 YP_001493438.1 CDS sucC NC_009881.1 586842 588002 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(586842..588002) Rickettsia akari str. Hartford 5645635 YP_001493439.1 CDS A1C_03225 NC_009881.1 588222 588461 R hypothetical protein complement(588222..588461) Rickettsia akari str. Hartford 5645223 YP_001493440.1 CDS A1C_03230 NC_009881.1 588753 590789 R COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; acylamino-acid-releasing protein complement(588753..590789) Rickettsia akari str. Hartford 5645224 YP_001493441.1 CDS A1C_03235 NC_009881.1 590878 591513 R COG4395 Uncharacterized protein conserved in bacteria; hypothetical protein complement(590878..591513) Rickettsia akari str. Hartford 5645225 YP_001493442.1 CDS rbfA NC_009881.1 591815 592204 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(591815..592204) Rickettsia akari str. Hartford 5645226 YP_001493443.1 CDS A1C_03245 NC_009881.1 592208 592633 R COG1238 Predicted membrane protein; hypothetical protein complement(592208..592633) Rickettsia akari str. Hartford 5645227 YP_001493444.1 CDS A1C_03250 NC_009881.1 592768 593289 D COG1714 Predicted membrane protein/domain; hypothetical protein 592768..593289 Rickettsia akari str. Hartford 5645228 YP_001493445.1 CDS recR NC_009881.1 593442 594065 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 593442..594065 Rickettsia akari str. Hartford 5645229 YP_001493446.1 CDS A1C_03260 NC_009881.1 594276 594626 D COG3023 Negative regulator of beta-lactamase expression; hypothetical protein 594276..594626 Rickettsia akari str. Hartford 5644773 YP_001493447.1 CDS A1C_03265 NC_009881.1 594825 594908 D hypothetical protein 594825..594908 Rickettsia akari str. Hartford 5644774 YP_001493448.1 CDS A1C_03270 NC_009881.1 595074 595514 R hypothetical protein complement(595074..595514) Rickettsia akari str. Hartford 5644775 YP_001493449.1 CDS A1C_03275 NC_009881.1 595676 595840 R hypothetical protein complement(595676..595840) Rickettsia akari str. Hartford 5644776 YP_001493450.1 CDS A1C_03280 NC_009881.1 595833 596078 R hypothetical protein complement(595833..596078) Rickettsia akari str. Hartford 5644777 YP_001493451.1 CDS A1C_03285 NC_009881.1 596305 596457 R hypothetical protein complement(596305..596457) Rickettsia akari str. Hartford 5644778 YP_001493452.1 CDS A1C_03290 NC_009881.1 596717 596920 R hypothetical protein complement(596717..596920) Rickettsia akari str. Hartford 5644779 YP_001493453.1 CDS ppnK NC_009881.1 597001 597768 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(597001..597768) Rickettsia akari str. Hartford 5644699 YP_001493454.1 CDS A1C_03300 NC_009881.1 597855 599537 D COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; hypothetical protein 597855..599537 Rickettsia akari str. Hartford 5644700 YP_001493455.1 CDS gpsA NC_009881.1 599616 599834 D NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 599616..599834 Rickettsia akari str. Hartford 5644701 YP_001493456.1 CDS gpsA NC_009881.1 599827 600780 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 599827..600780 Rickettsia akari str. Hartford 5644702 YP_001493457.1 CDS A1C_03315 NC_009881.1 601037 601210 D hypothetical protein 601037..601210 Rickettsia akari str. Hartford 5644703 YP_001493458.1 CDS A1C_03320 NC_009881.1 601203 601373 R hypothetical protein complement(601203..601373) Rickettsia akari str. Hartford 5644704 YP_001493459.1 CDS A1C_03325 NC_009881.1 601682 602611 D COG0679 Predicted permeases; permease 601682..602611 Rickettsia akari str. Hartford 5644705 YP_001493460.1 CDS A1C_03330 NC_009881.1 602670 603542 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 602670..603542 Rickettsia akari str. Hartford 5645708 YP_001493461.1 CDS A1C_03335 NC_009881.1 603763 604695 D COG0492 Thioredoxin reductase; thioredoxin reductase 603763..604695 Rickettsia akari str. Hartford 5645709 YP_001493462.1 CDS A1C_03340 NC_009881.1 604809 605024 D hypothetical protein 604809..605024 Rickettsia akari str. Hartford 5645710 YP_001493463.1 CDS A1C_03345 NC_009881.1 605041 605337 D hypothetical protein 605041..605337 Rickettsia akari str. Hartford 5645711 YP_001493464.1 CDS A1C_03350 NC_009881.1 605364 605576 D hypothetical protein 605364..605576 Rickettsia akari str. Hartford 5645712 YP_001493465.1 CDS A1C_03355 NC_009881.1 605665 606000 D COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 605665..606000 Rickettsia akari str. Hartford 5645713 YP_001493466.1 CDS A1C_03360 NC_009881.1 606034 606150 D hypothetical protein 606034..606150 Rickettsia akari str. Hartford 5645714 YP_001493467.1 CDS A1C_03365 NC_009881.1 606637 606834 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 606637..606834 Rickettsia akari str. Hartford 5645006 YP_001493468.1 CDS A1C_03370 NC_009881.1 607132 608568 D COG1012 NAD-dependent aldehyde dehydrogenases; succinate semialdehyde dehydrogenase 607132..608568 Rickettsia akari str. Hartford 5645007 YP_001493469.1 CDS A1C_03375 NC_009881.1 608684 609097 D hypothetical protein 608684..609097 Rickettsia akari str. Hartford 5645008 YP_001493470.1 CDS A1C_03380 NC_009881.1 609097 609942 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 609097..609942 Rickettsia akari str. Hartford 5645009 YP_001493471.1 CDS A1C_03385 NC_009881.1 610162 612123 D COG0210 Superfamily I DNA and RNA helicases; DNA helicase II 610162..612123 Rickettsia akari str. Hartford 5645010 YP_001493472.1 CDS A1C_03390 NC_009881.1 612214 612720 D hypothetical protein 612214..612720 Rickettsia akari str. Hartford 5645011 YP_001493473.1 CDS A1C_03395 NC_009881.1 612795 613064 D hypothetical protein 612795..613064 Rickettsia akari str. Hartford 5645012 YP_001493474.1 CDS A1C_03400 NC_009881.1 613253 613501 D hypothetical protein 613253..613501 Rickettsia akari str. Hartford 5644597 YP_001493475.1 CDS A1C_03405 NC_009881.1 613556 614923 D hypothetical protein 613556..614923 Rickettsia akari str. Hartford 5644598 YP_001493476.1 CDS A1C_03410 NC_009881.1 615269 616270 R catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase complement(615269..616270) Rickettsia akari str. Hartford 5644599 YP_001493477.1 CDS A1C_03415 NC_009881.1 616356 618692 D COG0466 ATP-dependent Lon protease, bacterial type; ATP-dependent protease La 616356..618692 Rickettsia akari str. Hartford 5644600 YP_001493478.1 CDS A1C_03420 NC_009881.1 618712 618897 R hypothetical protein complement(618712..618897) Rickettsia akari str. Hartford 5644601 YP_001493479.1 CDS A1C_03435 NC_009881.1 620393 620494 R hypothetical protein complement(620393..620494) Rickettsia akari str. Hartford 5644602 YP_001493480.1 CDS A1C_03440 NC_009881.1 621392 621610 D hypothetical protein 621392..621610 Rickettsia akari str. Hartford 5645467 YP_001493481.1 CDS A1C_03445 NC_009881.1 621809 622387 D COG1544 Ribosome-associated protein Y (PSrp-1); sigma(54) modulation protein 621809..622387 Rickettsia akari str. Hartford 5645468 YP_001493482.1 CDS A1C_03450 NC_009881.1 622387 622545 D COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily; carbonic anhydrase/acetyltransferase, isoleucine patch superfamily protein 622387..622545 Rickettsia akari str. Hartford 5645469 YP_001493483.1 CDS A1C_03455 NC_009881.1 623031 623918 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(623031..623918) Rickettsia akari str. Hartford 5645470 YP_001493484.1 CDS A1C_03460 NC_009881.1 623926 624225 R NADH dehydrogenase subunit N complement(623926..624225) Rickettsia akari str. Hartford 5645471 YP_001493485.1 CDS A1C_03465 NC_009881.1 624260 625264 R COG0492 Thioredoxin reductase; thioredoxin reductase complement(624260..625264) Rickettsia akari str. Hartford 5645472 YP_001493486.1 CDS A1C_03470 NC_009881.1 625941 626015 R ribonucleotide-diphosphate reductase subunit alpha complement(625941..626015) Rickettsia akari str. Hartford 5645187 YP_001493487.1 CDS A1C_03475 NC_009881.1 626002 626253 R hypothetical protein complement(626002..626253) Rickettsia akari str. Hartford 5645188 YP_001493488.1 CDS A1C_03480 NC_009881.1 626481 628304 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 626481..628304 Rickettsia akari str. Hartford 5645189 YP_001493489.1 CDS nrdF NC_009881.1 628552 629535 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 628552..629535 Rickettsia akari str. Hartford 5645190 YP_001493490.1 CDS A1C_03490 NC_009881.1 629688 632546 D COG1357 Uncharacterized low-complexity proteins; hypothetical protein 629688..632546 Rickettsia akari str. Hartford 5645191 YP_001493492.1 CDS A1C_03515 NC_009881.1 634142 634339 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 634142..634339 Rickettsia akari str. Hartford 5645193 YP_001493493.1 CDS A1C_03520 NC_009881.1 634372 634629 D hypothetical protein 634372..634629 Rickettsia akari str. Hartford 5644612 YP_001493494.1 CDS A1C_03525 NC_009881.1 634663 634848 D hypothetical protein 634663..634848 Rickettsia akari str. Hartford 5644613 YP_001493495.1 CDS miaA NC_009881.1 635172 636110 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(635172..636110) Rickettsia akari str. Hartford 5644614 YP_001493496.1 CDS A1C_03535 NC_009881.1 636513 637955 R COG1109 Phosphomannomutase; phosphomannomutase complement(636513..637955) Rickettsia akari str. Hartford 5644615 YP_001493497.1 CDS A1C_03540 NC_009881.1 638133 638855 R COG1137 ABC-type (unclassified) transport system, ATPase component; ABC transporter ATP-binding protein complement(638133..638855) Rickettsia akari str. Hartford 5644616 YP_001493498.1 CDS A1C_03545 NC_009881.1 638992 639369 R COG1934 Uncharacterized protein conserved in bacteria; hypothetical protein complement(638992..639369) Rickettsia akari str. Hartford 5644617 YP_001493499.1 CDS A1C_03550 NC_009881.1 639395 639994 R COG5375 Uncharacterized protein conserved in bacteria; hypothetical protein complement(639395..639994) Rickettsia akari str. Hartford 5644618 YP_001493500.1 CDS A1C_03555 NC_009881.1 640000 640959 R COG0794 Predicted sugar phosphate isomerase involved in capsule formation; KpsF protein complement(640000..640959) Rickettsia akari str. Hartford 5645131 YP_001493501.1 CDS A1C_03560 NC_009881.1 641211 643454 R COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase complement(641211..643454) Rickettsia akari str. Hartford 5645132 YP_001493502.1 CDS rpsO NC_009881.1 643615 643890 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(643615..643890) Rickettsia akari str. Hartford 5645133 YP_001493503.1 CDS truB NC_009881.1 643912 644793 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(643912..644793) Rickettsia akari str. Hartford 5645134 YP_001493504.1 CDS A1C_03575 NC_009881.1 644917 646452 D COG3202 ATP/ADP translocase; ADP,ATP carrier protein 644917..646452 Rickettsia akari str. Hartford 5645135 YP_001493505.1 CDS A1C_03580 NC_009881.1 646721 649771 D cell surface antigen 646721..649771 Rickettsia akari str. Hartford 5645136 YP_001493506.1 CDS A1C_03585 NC_009881.1 649808 650002 R hypothetical protein complement(649808..650002) Rickettsia akari str. Hartford 5645137 YP_001493507.1 CDS A1C_03590 NC_009881.1 650058 650255 R COG1943 Transposase and inactivated derivatives; transposase IS200-family protein complement(650058..650255) Rickettsia akari str. Hartford 5645013 YP_001493508.1 CDS A1C_03595 NC_009881.1 650622 651014 R COG1396 Predicted transcriptional regulators; hypothetical protein complement(650622..651014) Rickettsia akari str. Hartford 5645014 YP_001493509.1 CDS A1C_03600 NC_009881.1 651542 652369 D COG1295 Predicted membrane protein; ribonuclease BN 651542..652369 Rickettsia akari str. Hartford 5645015 YP_001493510.1 CDS A1C_03605 NC_009881.1 652487 653320 R COG0174 Glutamine synthetase; glutamine synthetase complement(652487..653320) Rickettsia akari str. Hartford 5645016 YP_001493511.1 CDS A1C_03610 NC_009881.1 653319 654041 D COG1496 Uncharacterized conserved protein; hypothetical protein 653319..654041 Rickettsia akari str. Hartford 5645017 YP_001493512.1 CDS A1C_03615 NC_009881.1 654461 654850 D COG0242 N-formylmethionyl-tRNA deformylase; polypeptide deformylase 654461..654850 Rickettsia akari str. Hartford 5645018 YP_001493513.1 CDS A1C_03620 NC_009881.1 655256 655621 D hypothetical protein 655256..655621 Rickettsia akari str. Hartford 5645019 YP_001493514.1 CDS A1C_03625 NC_009881.1 656163 656348 R hypothetical protein complement(656163..656348) Rickettsia akari str. Hartford 5645158 YP_001493515.1 CDS A1C_03630 NC_009881.1 656807 658150 R hypothetical protein complement(656807..658150) Rickettsia akari str. Hartford 5645159 YP_001493516.1 CDS A1C_03635 NC_009881.1 658350 658466 D pyruvate phosphate dikinase 658350..658466 Rickettsia akari str. Hartford 5645160 YP_001493517.1 CDS A1C_03640 NC_009881.1 658545 661181 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(658545..661181) Rickettsia akari str. Hartford 5645161 YP_001493518.1 CDS A1C_03645 NC_009881.1 662028 662696 D COG0625 Glutathione S-transferase; glutathione S-transferase 662028..662696 Rickettsia akari str. Hartford 5645162 YP_001493519.1 CDS A1C_03650 NC_009881.1 662659 663408 R COG4285 Uncharacterized conserved protein; hypothetical protein complement(662659..663408) Rickettsia akari str. Hartford 5645163 YP_001493520.1 CDS A1C_03655 NC_009881.1 663441 663602 R hypothetical protein complement(663441..663602) Rickettsia akari str. Hartford 5645164 YP_001493521.1 CDS A1C_03660 NC_009881.1 663484 664026 D COG1268 Uncharacterized conserved protein; BioY family protein 663484..664026 Rickettsia akari str. Hartford 5644869 YP_001493522.1 CDS A1C_03665 NC_009881.1 664260 665549 D COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 664260..665549 Rickettsia akari str. Hartford 5644870 YP_001493523.1 CDS A1C_03670 NC_009881.1 665708 666337 D COG0605 Superoxide dismutase; superoxide dismutase 665708..666337 Rickettsia akari str. Hartford 5644871 YP_001493524.1 CDS A1C_03690 NC_009881.1 667622 667732 D hypothetical protein 667622..667732 Rickettsia akari str. Hartford 5644872 YP_001493525.1 CDS A1C_03700 NC_009881.1 668122 668925 D COG0340 Biotin-(acetyl-CoA carboxylase) ligase; biotin--protein ligase 668122..668925 Rickettsia akari str. Hartford 5644873 YP_001493526.1 CDS A1C_03705 NC_009881.1 669089 669253 R hypothetical protein complement(669089..669253) Rickettsia akari str. Hartford 5644874 YP_001493527.1 CDS A1C_03710 NC_009881.1 669443 669718 D hypothetical protein 669443..669718 Rickettsia akari str. Hartford 5644875 YP_001493528.1 CDS A1C_03715 NC_009881.1 670773 671345 D hypothetical protein 670773..671345 Rickettsia akari str. Hartford 5645580 YP_001493529.1 CDS A1C_03720 NC_009881.1 671432 671515 D hypothetical protein 671432..671515 Rickettsia akari str. Hartford 5645581 YP_001493530.1 CDS A1C_03725 NC_009881.1 671524 671874 D COG5448 Uncharacterized conserved protein; hypothetical protein 671524..671874 Rickettsia akari str. Hartford 5645582 YP_001493531.1 CDS A1C_03730 NC_009881.1 672089 672433 D hypothetical protein 672089..672433 Rickettsia akari str. Hartford 5645583 YP_001493532.1 CDS A1C_03735 NC_009881.1 672448 672618 D COG5449 Uncharacterized conserved protein; hypothetical protein 672448..672618 Rickettsia akari str. Hartford 5645584 YP_001493533.1 CDS A1C_03740 NC_009881.1 672622 672795 D hypothetical protein 672622..672795 Rickettsia akari str. Hartford 5645585 YP_001493534.1 CDS A1C_03745 NC_009881.1 672782 673114 D COG5346 Predicted membrane protein; hypothetical protein 672782..673114 Rickettsia akari str. Hartford 5645586 YP_001493535.1 CDS infC NC_009881.1 673288 673731 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 673288..673731 Rickettsia akari str. Hartford 5644656 YP_001493536.1 CDS A1C_03755 NC_009881.1 674008 675246 D COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; branched-chain alpha-keto acid dehydrogenase subunit E2 674008..675246 Rickettsia akari str. Hartford 5644657 YP_001493537.1 CDS prfA NC_009881.1 675411 676478 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 675411..676478 Rickettsia akari str. Hartford 5644658 YP_001493538.1 CDS A1C_03765 NC_009881.1 676653 678416 D COG0608 Single-stranded DNA-specific exonuclease; single-stranded-DNA-specific exonuclease RecJ 676653..678416 Rickettsia akari str. Hartford 5644659 YP_001493539.1 CDS A1C_03770 NC_009881.1 678641 679957 D COG0500 SAM-dependent methyltransferases; putative methyltransferase 678641..679957 Rickettsia akari str. Hartford 5644660 YP_001493540.1 CDS rho NC_009881.1 680355 681731 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 680355..681731 Rickettsia akari str. Hartford 5644661 YP_001493541.1 CDS A1C_03790 NC_009881.1 682576 682824 D COG0776 Bacterial nucleoid DNA-binding protein; integration host factor beta-subunit 682576..682824 Rickettsia akari str. Hartford 5644662 YP_001493542.1 CDS A1C_03795 NC_009881.1 682899 683048 D hypothetical protein 682899..683048 Rickettsia akari str. Hartford 5644941 YP_001493543.1 CDS A1C_03800 NC_009881.1 683301 683504 D hypothetical protein 683301..683504 Rickettsia akari str. Hartford 5644942 YP_001493544.1 CDS A1C_03805 NC_009881.1 683507 683695 D COG3022 Uncharacterized protein conserved in bacteria; hypothetical protein 683507..683695 Rickettsia akari str. Hartford 5644943 YP_001493545.1 CDS A1C_03810 NC_009881.1 683891 684046 D COG0642 Signal transduction histidine kinase; Na+/proline symporter and signal transduction histidine kinase 683891..684046 Rickettsia akari str. Hartford 5644944 YP_001493546.1 CDS A1C_03815 NC_009881.1 684497 684577 D hypothetical protein 684497..684577 Rickettsia akari str. Hartford 5644945 YP_001493547.1 CDS A1C_03820 NC_009881.1 684574 684702 D microcin C7 resistance protein 684574..684702 Rickettsia akari str. Hartford 5644946 YP_001493548.1 CDS hemC NC_009881.1 684699 685604 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 684699..685604 Rickettsia akari str. Hartford 5644947 YP_001493549.1 CDS A1C_03830 NC_009881.1 685755 686738 R COG0142 Geranylgeranyl pyrophosphate synthase; octaprenyl-diphosphate synthase complement(685755..686738) Rickettsia akari str. Hartford 5645440 YP_001493550.1 CDS A1C_03835 NC_009881.1 686828 688483 R hypothetical protein complement(686828..688483) Rickettsia akari str. Hartford 5645441 YP_001493551.1 CDS A1C_03840 NC_009881.1 688480 690015 R COG3202 ATP/ADP translocase; ADP,ATP carrier protein complement(688480..690015) Rickettsia akari str. Hartford 5645442 YP_001493552.1 CDS A1C_03845 NC_009881.1 690094 691554 R COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide 1,2-glucosyltransferase RfaJ complement(690094..691554) Rickettsia akari str. Hartford 5645443 YP_001493553.1 CDS A1C_03850 NC_009881.1 692154 693473 D COG0477 Permeases of the major facilitator superfamily; AmpG-related permease 692154..693473 Rickettsia akari str. Hartford 5645444 YP_001493554.1 CDS A1C_03865 NC_009881.1 694070 694744 D hypothetical protein 694070..694744 Rickettsia akari str. Hartford 5645838 YP_001493555.1 CDS A1C_03870 NC_009881.1 694728 695420 D hypothetical protein 694728..695420 Rickettsia akari str. Hartford 5645839 YP_001493556.1 CDS A1C_03875 NC_009881.1 695413 696417 D COG0457 FOG: TPR repeat; hypothetical protein 695413..696417 Rickettsia akari str. Hartford 5645840 YP_001493557.1 CDS A1C_03880 NC_009881.1 696697 697416 R COG2945 Predicted hydrolase of the alpha/beta superfamily; hypothetical protein complement(696697..697416) Rickettsia akari str. Hartford 5645841 YP_001493558.1 CDS A1C_03885 NC_009881.1 697584 697850 D COG3077 DNA-damage-inducible protein J; DNA-damage-inducible protein J 697584..697850 Rickettsia akari str. Hartford 5645842 YP_001493559.1 CDS A1C_03890 NC_009881.1 697847 698041 D COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein 697847..698041 Rickettsia akari str. Hartford 5645843 YP_001493560.1 CDS A1C_03895 NC_009881.1 698175 698615 R COG5622 Protein required for attachment to host cells; hypothetical protein complement(698175..698615) Rickettsia akari str. Hartford 5645844 YP_001493561.1 CDS A1C_03900 NC_009881.1 698679 699254 R COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(698679..699254) Rickettsia akari str. Hartford 5645811 YP_001493562.1 CDS A1C_03905 NC_009881.1 699481 700473 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 699481..700473 Rickettsia akari str. Hartford 5645812 YP_001493563.1 CDS A1C_03910 NC_009881.1 700997 701539 D hydrolase or acyltransferase 700997..701539 Rickettsia akari str. Hartford 5645814 YP_001493564.1 CDS A1C_03915 NC_009881.1 701788 703605 R COG0006 Xaa-Pro aminopeptidase; aminopeptidase P complement(701788..703605) Rickettsia akari str. Hartford 5645816 YP_001493565.1 CDS A1C_03920 NC_009881.1 703652 704998 R COG0531 Amino acid transporters; putrescine-ornithine antiporter complement(703652..704998) Rickettsia akari str. Hartford 5644856 YP_001493566.1 CDS A1C_03925 NC_009881.1 705357 705620 R hypothetical protein complement(705357..705620) Rickettsia akari str. Hartford 5644857 YP_001493567.1 CDS A1C_03930 NC_009881.1 705617 705790 R hypothetical protein complement(705617..705790) Rickettsia akari str. Hartford 5644858 YP_001493568.1 CDS A1C_03935 NC_009881.1 705816 706040 R hypothetical protein complement(705816..706040) Rickettsia akari str. Hartford 5644859 YP_001493569.1 CDS A1C_03940 NC_009881.1 706206 706391 R hypothetical protein complement(706206..706391) Rickettsia akari str. Hartford 5644860 YP_001493570.1 CDS A1C_03945 NC_009881.1 706397 706504 R hypothetical protein complement(706397..706504) Rickettsia akari str. Hartford 5644861 YP_001493571.1 CDS A1C_03950 NC_009881.1 706666 706998 R COG0316 Uncharacterized conserved protein; Iron-sulfur cluster assembly accessory protein complement(706666..706998) Rickettsia akari str. Hartford 5645672 YP_001493572.1 CDS A1C_03955 NC_009881.1 707002 707397 R COG0822 NifU homolog involved in Fe-S cluster formation; scaffold protein complement(707002..707397) Rickettsia akari str. Hartford 5645673 YP_001493573.1 CDS A1C_03960 NC_009881.1 707491 708723 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(707491..708723) Rickettsia akari str. Hartford 5645674 YP_001493574.1 CDS A1C_03965 NC_009881.1 708766 709881 R COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; hypothetical protein complement(708766..709881) Rickettsia akari str. Hartford 5645675 YP_001493575.1 CDS A1C_03970 NC_009881.1 709878 710264 R COG1959 Predicted transcriptional regulator; Iron-sulfur cluster assembly transcription factor IscR complement(709878..710264) Rickettsia akari str. Hartford 5645676 YP_001493576.1 CDS A1C_03975 NC_009881.1 710823 711695 R hypothetical protein complement(710823..711695) Rickettsia akari str. Hartford 5645677 YP_001493577.1 CDS A1C_03980 NC_009881.1 712536 712649 R NTPase complement(712536..712649) Rickettsia akari str. Hartford 5645678 YP_001493578.1 CDS A1C_03985 NC_009881.1 712868 714244 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 712868..714244 Rickettsia akari str. Hartford 5645075 YP_001493579.1 CDS A1C_03990 NC_009881.1 714231 715772 R hypothetical protein complement(714231..715772) Rickettsia akari str. Hartford 5645076 YP_001493580.1 CDS A1C_03995 NC_009881.1 715867 716859 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(715867..716859) Rickettsia akari str. Hartford 5645077 YP_001493581.1 CDS A1C_04000 NC_009881.1 717412 719358 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(717412..719358) Rickettsia akari str. Hartford 5645078 YP_001493582.1 CDS A1C_04005 NC_009881.1 719426 719992 D COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; aromatic acid decarboxylase 719426..719992 Rickettsia akari str. Hartford 5645079 YP_001493583.1 CDS A1C_04010 NC_009881.1 720179 721663 D unwinds double stranded DNA; replicative DNA helicase 720179..721663 Rickettsia akari str. Hartford 5645080 YP_001493584.1 CDS A1C_04015 NC_009881.1 722162 722368 R putative to amino acid permeases complement(722162..722368) Rickettsia akari str. Hartford 5645081 YP_001493585.1 CDS A1C_04020 NC_009881.1 722481 722720 R COG0814 Amino acid permeases; putative to amino acid permeases complement(722481..722720) Rickettsia akari str. Hartford 5645270 YP_001493586.1 CDS A1C_04025 NC_009881.1 723529 724218 D COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; ribosomal large subunit pseudouridine synthase 723529..724218 Rickettsia akari str. Hartford 5645271 YP_001493587.1 CDS A1C_04030 NC_009881.1 724269 727133 D COG1357 Uncharacterized low-complexity proteins; hypothetical protein 724269..727133 Rickettsia akari str. Hartford 5645272 YP_001493588.1 CDS A1C_04035 NC_009881.1 727138 727716 D COG0742 N6-adenine-specific methylase; N6-adenine-specific methylase 727138..727716 Rickettsia akari str. Hartford 5645273 YP_001493589.1 CDS A1C_04040 NC_009881.1 727815 729155 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 727815..729155 Rickettsia akari str. Hartford 5645274 YP_001493590.1 CDS A1C_04045 NC_009881.1 729152 729469 D COG0191 Fructose/tagatose bisphosphate aldolase; hypothetical protein 729152..729469 Rickettsia akari str. Hartford 5645275 YP_001493591.1 CDS recO NC_009881.1 729544 730257 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 729544..730257 Rickettsia akari str. Hartford 5645276 YP_001493592.1 CDS A1C_04055 NC_009881.1 730469 731155 D COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; putative glycoprotein endopeptidase 730469..731155 Rickettsia akari str. Hartford 5644825 YP_001493593.1 CDS A1C_04060 NC_009881.1 731189 732217 R COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); hypothetical protein complement(731189..732217) Rickettsia akari str. Hartford 5644826 YP_001493594.1 CDS infB NC_009881.1 732469 734958 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(732469..734958) Rickettsia akari str. Hartford 5644827 YP_001493595.1 CDS nusA NC_009881.1 735212 736723 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(735212..736723) Rickettsia akari str. Hartford 5644828 YP_001493596.1 CDS A1C_04075 NC_009881.1 736813 737313 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(736813..737313) Rickettsia akari str. Hartford 5644829 YP_001493597.1 CDS A1C_04080 NC_009881.1 737653 738042 R COG3177 Uncharacterized conserved protein; hypothetical protein complement(737653..738042) Rickettsia akari str. Hartford 5644830 YP_001493598.1 CDS A1C_04085 NC_009881.1 738112 738204 R hypothetical protein complement(738112..738204) Rickettsia akari str. Hartford 5644831 YP_001493599.1 CDS A1C_04090 NC_009881.1 738643 739386 R COG1189 Predicted rRNA methylase; hemolysin A complement(738643..739386) Rickettsia akari str. Hartford 5645417 YP_001493600.1 CDS A1C_04095 NC_009881.1 739550 740785 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(739550..740785) Rickettsia akari str. Hartford 5645418 YP_001493601.1 CDS A1C_04100 NC_009881.1 740902 741069 R hypothetical protein complement(740902..741069) Rickettsia akari str. Hartford 5645419 YP_001493602.1 CDS A1C_04105 NC_009881.1 741824 742192 R hypothetical protein complement(741824..742192) Rickettsia akari str. Hartford 5645420 YP_001493603.1 CDS A1C_04110 NC_009881.1 742194 742532 R hypothetical protein complement(742194..742532) Rickettsia akari str. Hartford 5645421 YP_001493604.1 CDS A1C_04115 NC_009881.1 742836 743762 R COG0354 Predicted aminomethyltransferase related to GcvT; hypothetical protein complement(742836..743762) Rickettsia akari str. Hartford 5645422 YP_001493605.1 CDS A1C_04120 NC_009881.1 743875 744666 D COG1723 Uncharacterized conserved protein; hypothetical protein 743875..744666 Rickettsia akari str. Hartford 5645423 YP_001493606.1 CDS A1C_04125 NC_009881.1 744676 745521 D COG0349 Ribonuclease D; ribonuclease D 744676..745521 Rickettsia akari str. Hartford 5645445 YP_001493607.1 CDS A1C_04130 NC_009881.1 745747 746091 R COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase complement(745747..746091) Rickettsia akari str. Hartford 5645446 YP_001493608.1 CDS A1C_04135 NC_009881.1 746259 747638 R Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(746259..747638) Rickettsia akari str. Hartford 5645447 YP_001493609.1 CDS A1C_04140 NC_009881.1 747786 748466 R COG0500 SAM-dependent methyltransferases; biotin synthesis protein BioC complement(747786..748466) Rickettsia akari str. Hartford 5645448 YP_001493610.1 CDS A1C_04145 NC_009881.1 748646 748867 R hypothetical protein complement(748646..748867) Rickettsia akari str. Hartford 5645449 YP_001493611.1 CDS A1C_04150 NC_009881.1 749086 749601 R hypothetical protein complement(749086..749601) Rickettsia akari str. Hartford 5645450 YP_001493612.1 CDS A1C_04155 NC_009881.1 749699 750520 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); hypothetical protein complement(749699..750520) Rickettsia akari str. Hartford 5645451 YP_001493613.1 CDS A1C_04160 NC_009881.1 751326 751499 R hypothetical protein complement(751326..751499) Rickettsia akari str. Hartford 5645332 YP_001493614.1 CDS A1C_04165 NC_009881.1 751554 751949 R hypothetical protein complement(751554..751949) Rickettsia akari str. Hartford 5645333 YP_001493615.1 CDS rpmJ NC_009881.1 752054 752179 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 752054..752179 Rickettsia akari str. Hartford 5645334 YP_001493616.1 CDS A1C_04175 NC_009881.1 752197 752955 D COG0217 Uncharacterized conserved protein; hypothetical protein 752197..752955 Rickettsia akari str. Hartford 5645335 YP_001493617.1 CDS A1C_04180 NC_009881.1 752952 753698 D COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); UDP-N-acetylglucosamine pyrophosphorylase 752952..753698 Rickettsia akari str. Hartford 5645336 YP_001493618.1 CDS A1C_04190 NC_009881.1 754483 754638 D isopentenyl pyrophosphate isomerase 754483..754638 Rickettsia akari str. Hartford 5645338 YP_001493619.1 CDS A1C_04195 NC_009881.1 754941 755969 R catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase complement(754941..755969) Rickettsia akari str. Hartford 5645230 YP_001493620.1 CDS A1C_04200 NC_009881.1 756146 756304 D acetyltransferase 756146..756304 Rickettsia akari str. Hartford 5645231 YP_001493621.1 CDS A1C_04205 NC_009881.1 756408 756839 D ankyrin repeat-containing protein 756408..756839 Rickettsia akari str. Hartford 5645232 YP_001493622.1 CDS A1C_04210 NC_009881.1 756887 756958 D hypothetical protein 756887..756958 Rickettsia akari str. Hartford 5645233 YP_001493623.1 CDS A1C_04215 NC_009881.1 756985 757128 R hypothetical protein complement(756985..757128) Rickettsia akari str. Hartford 5645234 YP_001493624.1 CDS A1C_04220 NC_009881.1 757465 757683 D hypothetical protein 757465..757683 Rickettsia akari str. Hartford 5645235 YP_001493625.1 CDS A1C_04225 NC_009881.1 757686 757889 R acetyltransferase complement(757686..757889) Rickettsia akari str. Hartford 5645236 YP_001493626.1 CDS A1C_04230 NC_009881.1 757986 758300 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase complement(757986..758300) Rickettsia akari str. Hartford 5645237 YP_001493627.1 CDS clpP NC_009881.1 759326 759931 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(759326..759931) Rickettsia akari str. Hartford 5645588 YP_001493628.1 CDS rpsA NC_009881.1 760175 761881 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(760175..761881) Rickettsia akari str. Hartford 5645589 YP_001493629.1 CDS cmk NC_009881.1 762143 762802 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(762143..762802) Rickettsia akari str. Hartford 5645590 YP_001493630.1 CDS A1C_04250 NC_009881.1 763363 763656 R transposase Tn5 complement(763363..763656) Rickettsia akari str. Hartford 5645592 YP_001493631.1 CDS A1C_04255 NC_009881.1 763779 763928 R transposase Tn5 complement(763779..763928) Rickettsia akari str. Hartford 5645027 YP_001493632.1 CDS A1C_04260 NC_009881.1 764964 765272 R COG1301 Na+/H+-dicarboxylate symporters; hypothetical protein complement(764964..765272) Rickettsia akari str. Hartford 5645028 YP_001493633.1 CDS A1C_04265 NC_009881.1 765370 765666 R hypothetical protein complement(765370..765666) Rickettsia akari str. Hartford 5645029 YP_001493634.1 CDS A1C_04270 NC_009881.1 765704 766015 D hypothetical protein 765704..766015 Rickettsia akari str. Hartford 5645030 YP_001493635.1 CDS A1C_04275 NC_009881.1 766674 766805 R hypothetical protein complement(766674..766805) Rickettsia akari str. Hartford 5645031 YP_001493636.1 CDS A1C_04280 NC_009881.1 767339 767434 D hypothetical protein 767339..767434 Rickettsia akari str. Hartford 5645032 YP_001493637.1 CDS A1C_04285 NC_009881.1 767434 767568 D hypothetical protein 767434..767568 Rickettsia akari str. Hartford 5644809 YP_001493638.1 CDS A1C_04290 NC_009881.1 767600 767683 D hypothetical protein 767600..767683 Rickettsia akari str. Hartford 5644810 YP_001493639.1 CDS A1C_04295 NC_009881.1 767744 767881 D hypothetical protein 767744..767881 Rickettsia akari str. Hartford 5644811 YP_001493640.1 CDS A1C_04300 NC_009881.1 767973 768101 D hypothetical protein 767973..768101 Rickettsia akari str. Hartford 5644812 YP_001493641.1 CDS A1C_04305 NC_009881.1 768141 768359 D COG3328 Transposase and inactivated derivatives; transposase, mutator type 768141..768359 Rickettsia akari str. Hartford 5644813 YP_001493642.1 CDS A1C_04310 NC_009881.1 768858 769121 D COG3328 Transposase and inactivated derivatives; transposase 768858..769121 Rickettsia akari str. Hartford 5644814 YP_001493643.1 CDS A1C_04315 NC_009881.1 769137 769331 R COG1943 Transposase and inactivated derivatives; transposase IS200-family protein complement(769137..769331) Rickettsia akari str. Hartford 5644815 YP_001493644.1 CDS A1C_04320 NC_009881.1 771031 776712 D COG2373 Large extracellular alpha-helical protein; large extracellular alpha-helical protein 771031..776712 Rickettsia akari str. Hartford 5645345 YP_001493645.1 CDS A1C_04325 NC_009881.1 776810 778975 R COG1250 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase complement(776810..778975) Rickettsia akari str. Hartford 5645346 YP_001493646.1 CDS A1C_04330 NC_009881.1 779229 779423 R hypothetical protein complement(779229..779423) Rickettsia akari str. Hartford 5645347 YP_001493647.1 CDS A1C_04335 NC_009881.1 779804 780403 R COG0474 Cation transport ATPase; hypothetical protein complement(779804..780403) Rickettsia akari str. Hartford 5645348 YP_001493648.1 CDS A1C_04340 NC_009881.1 780372 780728 R hypothetical protein complement(780372..780728) Rickettsia akari str. Hartford 5645349 YP_001493649.1 CDS A1C_04345 NC_009881.1 780834 781004 R 2-octaprenyl-6-methoxyphenyl hydroxylase complement(780834..781004) Rickettsia akari str. Hartford 5645350 YP_001493650.1 CDS A1C_04350 NC_009881.1 781354 782490 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(781354..782490) Rickettsia akari str. Hartford 5644832 YP_001493651.1 CDS A1C_04355 NC_009881.1 782471 782737 R subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit F complement(782471..782737) Rickettsia akari str. Hartford 5644833 YP_001493652.1 CDS A1C_04360 NC_009881.1 783159 784586 D COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; nitrogen assimilation regulatory protein NtrX 783159..784586 Rickettsia akari str. Hartford 5644834 YP_001493653.1 CDS A1C_04365 NC_009881.1 784579 786324 D COG1357 Uncharacterized low-complexity proteins; hypothetical protein 784579..786324 Rickettsia akari str. Hartford 5644835 YP_001493654.1 CDS A1C_04370 NC_009881.1 786580 787578 R hypothetical protein complement(786580..787578) Rickettsia akari str. Hartford 5644836 YP_001493655.1 CDS A1C_04375 NC_009881.1 787837 787989 R hypothetical protein complement(787837..787989) Rickettsia akari str. Hartford 5644837 YP_001493656.1 CDS A1C_04380 NC_009881.1 788080 788694 R COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein complement(788080..788694) Rickettsia akari str. Hartford 5644838 YP_001493657.1 CDS A1C_04385 NC_009881.1 789117 790901 R COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein complement(789117..790901) Rickettsia akari str. Hartford 5644839 YP_001493658.1 CDS A1C_04390 NC_009881.1 790891 791412 R hypothetical protein complement(790891..791412) Rickettsia akari str. Hartford 5644848 YP_001493659.1 CDS A1C_04395 NC_009881.1 791777 793462 R COG0768 Cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein complement(791777..793462) Rickettsia akari str. Hartford 5644849 YP_001493660.1 CDS A1C_04400 NC_009881.1 793613 794011 R cell division protein FtsL complement(793613..794011) Rickettsia akari str. Hartford 5644850 YP_001493661.1 CDS mraW NC_009881.1 794295 795215 R COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW complement(794295..795215) Rickettsia akari str. Hartford 5644851 YP_001493662.1 CDS A1C_04410 NC_009881.1 795215 795664 R MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ complement(795215..795664) Rickettsia akari str. Hartford 5644852 YP_001493663.1 CDS A1C_04415 NC_009881.1 796216 797625 D COG0591 Na+/proline symporter; Sodium/pantothenate symporter 796216..797625 Rickettsia akari str. Hartford 5644853 YP_001493664.1 CDS A1C_04420 NC_009881.1 797847 798023 D COG2161 Antitoxin of toxin-antitoxin stability system; antitoxin of toxin-antitoxin system StbD 797847..798023 Rickettsia akari str. Hartford 5644854 YP_001493665.1 CDS A1C_04425 NC_009881.1 798086 798316 D toxin of toxin-antitoxin system 798086..798316 Rickettsia akari str. Hartford 5644855 YP_001493666.1 CDS uvrC NC_009881.1 798356 800311 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(798356..800311) Rickettsia akari str. Hartford 5645752 YP_001493667.1 CDS A1C_04435 NC_009881.1 800407 800937 R COG2847 Uncharacterized protein conserved in bacteria; hypothetical protein complement(800407..800937) Rickettsia akari str. Hartford 5645753 YP_001493668.1 CDS A1C_04440 NC_009881.1 801086 801280 R COG4912 Predicted DNA alkylation repair enzyme; hypothetical protein complement(801086..801280) Rickettsia akari str. Hartford 5645754 YP_001493669.1 CDS A1C_04455 NC_009881.1 802302 802598 D hypothetical protein 802302..802598 Rickettsia akari str. Hartford 5645755 YP_001493670.1 CDS A1C_04460 NC_009881.1 802591 802701 D hypothetical protein 802591..802701 Rickettsia akari str. Hartford 5645756 YP_001493671.1 CDS A1C_04465 NC_009881.1 803291 803554 R hypothetical protein complement(803291..803554) Rickettsia akari str. Hartford 5645757 YP_001493672.1 CDS A1C_04470 NC_009881.1 803956 804171 R hypothetical protein complement(803956..804171) Rickettsia akari str. Hartford 5645759 YP_001493673.1 CDS A1C_04475 NC_009881.1 804359 804907 R COG0666 FOG: Ankyrin repeat; ankyrin repeat-containing protein complement(804359..804907) Rickettsia akari str. Hartford 5645339 YP_001493674.1 CDS A1C_04480 NC_009881.1 804983 805078 R hypothetical protein complement(804983..805078) Rickettsia akari str. Hartford 5645340 YP_001493675.1 CDS A1C_04485 NC_009881.1 805549 808269 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(805549..808269) Rickettsia akari str. Hartford 5645341 YP_001493676.1 CDS A1C_04490 NC_009881.1 808520 809368 D COG0760 Parvulin-like peptidyl-prolyl isomerase; protein export protein prsA 808520..809368 Rickettsia akari str. Hartford 5645342 YP_001493677.1 CDS acpS NC_009881.1 809625 810005 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(809625..810005) Rickettsia akari str. Hartford 5645343 YP_001493678.1 CDS rpoZ NC_009881.1 810006 810389 R Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(810006..810389) Rickettsia akari str. Hartford 5645344 YP_001493679.1 CDS A1C_04505 NC_009881.1 810559 811818 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(810559..811818) Rickettsia akari str. Hartford 5645512 YP_001493680.1 CDS gyrB NC_009881.1 812158 814581 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(812158..814581) Rickettsia akari str. Hartford 5645513 YP_001493681.1 CDS A1C_04515 NC_009881.1 814806 815666 D COG0647 Predicted sugar phosphatases of the HAD superfamily; HAD family hydrolase 814806..815666 Rickettsia akari str. Hartford 5645514 YP_001493682.1 CDS A1C_04520 NC_009881.1 816336 817706 D COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); magnesium transporter 816336..817706 Rickettsia akari str. Hartford 5645516 YP_001493683.1 CDS A1C_04525 NC_009881.1 818072 818317 R hypothetical protein complement(818072..818317) Rickettsia akari str. Hartford 5645517 YP_001493684.1 CDS A1C_04540 NC_009881.1 819015 819320 R proline/betaine transporter complement(819015..819320) Rickettsia akari str. Hartford 5645524 YP_001493685.1 CDS yajC NC_009881.1 821488 821574 R preprotein translocase subunit YajC complement(821488..821574) Rickettsia akari str. Hartford 5645526 YP_001493686.1 CDS yajC NC_009881.1 821649 822077 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 821649..822077 Rickettsia akari str. Hartford 5645527 YP_001493687.1 CDS secD NC_009881.1 822061 823617 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 822061..823617 Rickettsia akari str. Hartford 5645528 YP_001493688.1 CDS A1C_04570 NC_009881.1 823860 824477 D COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems; sco2 protein 823860..824477 Rickettsia akari str. Hartford 5645529 YP_001493689.1 CDS A1C_04575 NC_009881.1 824579 824965 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 824579..824965 Rickettsia akari str. Hartford 5645530 YP_001493690.1 CDS A1C_04580 NC_009881.1 825093 825614 D catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 825093..825614 Rickettsia akari str. Hartford 5644663 YP_001493691.1 CDS A1C_04585 NC_009881.1 825847 827370 D COG0728 Uncharacterized membrane protein, putative virulence factor; virulence factor mviN 825847..827370 Rickettsia akari str. Hartford 5644664 YP_001493692.1 CDS A1C_04590 NC_009881.1 827351 828097 D F pilin acetylation protein TraX 827351..828097 Rickettsia akari str. Hartford 5644665 YP_001493693.1 CDS A1C_04595 NC_009881.1 828171 828773 D hypothetical protein 828171..828773 Rickettsia akari str. Hartford 5644666 YP_001493694.1 CDS A1C_04600 NC_009881.1 829627 831858 R COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG complement(829627..831858) Rickettsia akari str. Hartford 5644667 YP_001493695.1 CDS A1C_04605 NC_009881.1 832429 832563 D hypothetical protein 832429..832563 Rickettsia akari str. Hartford 5644668 YP_001493696.1 CDS A1C_04610 NC_009881.1 832750 833955 R hypothetical protein complement(832750..833955) Rickettsia akari str. Hartford 5644669 YP_001493697.1 CDS A1C_04615 NC_009881.1 834114 834335 D COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; succinyl-CoA:3-ketoacid-coenzyme A transferase 834114..834335 Rickettsia akari str. Hartford 5644670 YP_001493698.1 CDS A1C_04620 NC_009881.1 834332 834415 D succinyl-CoA:3-ketoacid-coenzyme A transferase 834332..834415 Rickettsia akari str. Hartford 5644604 YP_001493699.1 CDS A1C_04625 NC_009881.1 834567 834812 D COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; hypothetical protein 834567..834812 Rickettsia akari str. Hartford 5644605 YP_001493700.1 CDS A1C_04650 NC_009881.1 836378 837949 R Actin polymerization protein RickA complement(836378..837949) Rickettsia akari str. Hartford 5644606 YP_001493701.1 CDS mraY NC_009881.1 836934 837068 D phospho-N-acetylmuramoyl-pentapeptide- transferase 836934..837068 Rickettsia akari str. Hartford 5644607 YP_001493702.1 CDS mraY NC_009881.1 838033 839178 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(838033..839178) Rickettsia akari str. Hartford 5644608 YP_001493703.1 CDS A1C_04665 NC_009881.1 839258 840607 R COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase complement(839258..840607) Rickettsia akari str. Hartford 5644609 YP_001493704.1 CDS murE NC_009881.1 840749 842191 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(840749..842191) Rickettsia akari str. Hartford 5644610 YP_001493705.1 CDS A1C_04675 NC_009881.1 842384 845749 R COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor complement(842384..845749) Rickettsia akari str. Hartford 5644611 YP_001493706.1 CDS A1C_04680 NC_009881.1 845761 846024 R COG2938 Uncharacterized conserved protein; hypothetical protein complement(845761..846024) Rickettsia akari str. Hartford 5644817 YP_001493707.1 CDS A1C_04685 NC_009881.1 846344 846715 D COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 846344..846715 Rickettsia akari str. Hartford 5644818 YP_001493708.1 CDS dnaA NC_009881.1 846716 848107 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 846716..848107 Rickettsia akari str. Hartford 5644819 YP_001493709.1 CDS A1C_04695 NC_009881.1 848254 848589 R hypothetical protein complement(848254..848589) Rickettsia akari str. Hartford 5644820 YP_001493710.1 CDS A1C_04700 NC_009881.1 848626 848841 R hypothetical protein complement(848626..848841) Rickettsia akari str. Hartford 5644821 YP_001493711.1 CDS A1C_04705 NC_009881.1 848849 849082 R hypothetical protein complement(848849..849082) Rickettsia akari str. Hartford 5644822 YP_001493712.1 CDS A1C_04710 NC_009881.1 850045 851553 D COG3621 Patatin; patatin-like phospholipase 850045..851553 Rickettsia akari str. Hartford 5644823 YP_001493713.1 CDS A1C_04715 NC_009881.1 851757 852980 R COG0477 Permeases of the major facilitator superfamily; bicyclomycin resistance protein complement(851757..852980) Rickettsia akari str. Hartford 5644824 YP_001493714.1 CDS A1C_04730 NC_009881.1 854013 855110 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(854013..855110) Rickettsia akari str. Hartford 5645480 YP_001493715.1 CDS A1C_04735 NC_009881.1 855067 855216 R acetyltransferase complement(855067..855216) Rickettsia akari str. Hartford 5645481 YP_001493716.1 CDS A1C_04740 NC_009881.1 855358 855534 R acetyltransferase complement(855358..855534) Rickettsia akari str. Hartford 5645482 YP_001493717.1 CDS A1C_04745 NC_009881.1 855694 856251 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(855694..856251) Rickettsia akari str. Hartford 5645483 YP_001493718.1 CDS A1C_04750 NC_009881.1 856484 857083 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(856484..857083) Rickettsia akari str. Hartford 5645484 YP_001493719.1 CDS A1C_04755 NC_009881.1 857455 858132 R COG0602 Organic radical activating enzymes; organic radical activating protein complement(857455..858132) Rickettsia akari str. Hartford 5645485 YP_001493720.1 CDS rpmI NC_009881.1 858253 858387 R 50S ribosomal protein L35 complement(858253..858387) Rickettsia akari str. Hartford 5645486 YP_001493721.1 CDS rpmI NC_009881.1 858749 858955 D COG0291 Ribosomal protein L35; 50S ribosomal protein L35 858749..858955 Rickettsia akari str. Hartford 5645487 YP_001493722.1 CDS rplT NC_009881.1 858976 859329 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 858976..859329 Rickettsia akari str. Hartford 5644735 YP_001493723.1 CDS rpmH NC_009881.1 859456 859590 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 859456..859590 Rickettsia akari str. Hartford 5644736 YP_001493724.1 CDS rnpA NC_009881.1 859610 859966 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 859610..859966 Rickettsia akari str. Hartford 5644737 YP_001493725.1 CDS A1C_04785 NC_009881.1 860414 860740 R hypothetical protein complement(860414..860740) Rickettsia akari str. Hartford 5644738 YP_001493726.1 CDS A1C_04790 NC_009881.1 861045 861266 R hypothetical protein complement(861045..861266) Rickettsia akari str. Hartford 5644739 YP_001493727.1 CDS A1C_04795 NC_009881.1 861315 861599 R hypothetical protein complement(861315..861599) Rickettsia akari str. Hartford 5644740 YP_001493728.1 CDS A1C_04800 NC_009881.1 861612 861776 R hypothetical protein complement(861612..861776) Rickettsia akari str. Hartford 5644741 YP_001493729.1 CDS A1C_04815 NC_009881.1 866172 866693 R COG3173 Predicted aminoglycoside phosphotransferase; acetyltransferase complement(866172..866693) Rickettsia akari str. Hartford 5645796 YP_001493730.1 CDS A1C_04820 NC_009881.1 867123 868922 R COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; nitrogen regulation protein NtrY complement(867123..868922) Rickettsia akari str. Hartford 5645797 YP_001493731.1 CDS rpsU NC_009881.1 869215 869415 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(869215..869415) Rickettsia akari str. Hartford 5645798 YP_001493732.1 CDS A1C_04830 NC_009881.1 869496 870104 D COG5590 Uncharacterized conserved protein; hypothetical protein 869496..870104 Rickettsia akari str. Hartford 5645799 YP_001493733.1 CDS A1C_04835 NC_009881.1 870118 870495 R COG1848 Predicted nucleic acid-binding protein, contains PIN domain; hypothetical protein complement(870118..870495) Rickettsia akari str. Hartford 5645800 YP_001493734.1 CDS ileS NC_009881.1 870809 874120 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 870809..874120 Rickettsia akari str. Hartford 5645801 YP_001493735.1 CDS A1C_04845 NC_009881.1 874204 874593 D hypothetical protein 874204..874593 Rickettsia akari str. Hartford 5645802 YP_001493736.1 CDS A1C_04850 NC_009881.1 874942 875145 D hypothetical protein 874942..875145 Rickettsia akari str. Hartford 5644758 YP_001493737.1 CDS A1C_04855 NC_009881.1 875131 877128 R COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; propionyl-CoA carboxylase subunit alpha complement(875131..877128) Rickettsia akari str. Hartford 5644759 YP_001493738.1 CDS A1C_04860 NC_009881.1 877333 878877 R COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); propionyl-CoA carboxylase subunit beta complement(877333..878877) Rickettsia akari str. Hartford 5644760 YP_001493739.1 CDS A1C_04865 NC_009881.1 878951 879094 D acylglycerophosphoethanolamine acyltransferase 878951..879094 Rickettsia akari str. Hartford 5644761 YP_001493740.1 CDS A1C_04870 NC_009881.1 879156 879290 D hypothetical protein 879156..879290 Rickettsia akari str. Hartford 5644762 YP_001493741.1 CDS A1C_04875 NC_009881.1 879448 882918 D Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein; acylglycerophosphoethanolamine acyltransferase 879448..882918 Rickettsia akari str. Hartford 5644763 YP_001493742.1 CDS A1C_04880 NC_009881.1 883189 883458 R COG3070 Regulator of competence-specific genes; hypothetical protein complement(883189..883458) Rickettsia akari str. Hartford 5644764 YP_001493743.1 CDS A1C_04885 NC_009881.1 883534 884295 R COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Zinc/manganese ABC transporter permease protein complement(883534..884295) Rickettsia akari str. Hartford 5644765 YP_001493744.1 CDS A1C_04890 NC_009881.1 884381 885136 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 884381..885136 Rickettsia akari str. Hartford 5645636 YP_001493745.1 CDS gltX NC_009881.1 885207 886598 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 885207..886598 Rickettsia akari str. Hartford 5645637 YP_001493746.1 CDS A1C_04900 NC_009881.1 886595 887161 D COG5342 Invasion protein B, involved in pathogenesis; hypothetical protein 886595..887161 Rickettsia akari str. Hartford 5645638 YP_001493747.1 CDS A1C_04905 NC_009881.1 887840 887983 R hypothetical protein complement(887840..887983) Rickettsia akari str. Hartford 5645639 YP_001493748.1 CDS A1C_04920 NC_009881.1 889255 889596 R COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein complement(889255..889596) Rickettsia akari str. Hartford 5645640 YP_001493749.1 CDS groEL NC_009881.1 890315 891961 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(890315..891961) Rickettsia akari str. Hartford 5645641 YP_001493750.1 CDS groES NC_009881.1 891988 892275 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(891988..892275) Rickettsia akari str. Hartford 5645642 YP_001493751.1 CDS A1C_04945 NC_009881.1 893672 893818 R hypothetical protein complement(893672..893818) Rickettsia akari str. Hartford 5645643 YP_001493752.1 CDS rph NC_009881.1 894478 895197 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(894478..895197) Rickettsia akari str. Hartford 5645875 YP_001493753.1 CDS A1C_04955 NC_009881.1 895325 895861 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 895325..895861 Rickettsia akari str. Hartford 5645876 YP_001493754.1 CDS A1C_04960 NC_009881.1 896007 897062 D COG0628 Predicted permease; hypothetical protein 896007..897062 Rickettsia akari str. Hartford 5645877 YP_001493755.1 CDS A1C_04965 NC_009881.1 897185 897853 D COG0593 ATPase involved in DNA replication initiation; hypothetical protein 897185..897853 Rickettsia akari str. Hartford 5645878 YP_001493756.1 CDS A1C_04970 NC_009881.1 898319 898639 D COG0477 Permeases of the major facilitator superfamily; MFS type sugar transporter 898319..898639 Rickettsia akari str. Hartford 5645879 YP_001493757.1 CDS rpsT NC_009881.1 899986 900258 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(899986..900258) Rickettsia akari str. Hartford 5645881 YP_001493758.1 CDS rplQ NC_009881.1 900270 900686 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(900270..900686) Rickettsia akari str. Hartford 5645452 YP_001493759.1 CDS A1C_04985 NC_009881.1 900693 901715 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(900693..901715) Rickettsia akari str. Hartford 5645453 YP_001493760.1 CDS A1C_04990 NC_009881.1 901734 902117 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(901734..902117) Rickettsia akari str. Hartford 5645454 YP_001493761.1 CDS rpsM NC_009881.1 902142 902519 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(902142..902519) Rickettsia akari str. Hartford 5645455 YP_001493762.1 CDS adk NC_009881.1 902578 903216 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(902578..903216) Rickettsia akari str. Hartford 5645456 YP_001493763.1 CDS secY NC_009881.1 903232 904533 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(903232..904533) Rickettsia akari str. Hartford 5645457 YP_001493764.1 CDS rplO NC_009881.1 904537 904998 R late assembly protein; 50S ribosomal protein L15 complement(904537..904998) Rickettsia akari str. Hartford 5645458 YP_001493765.1 CDS rpmD NC_009881.1 905012 905203 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(905012..905203) Rickettsia akari str. Hartford 5645459 YP_001493766.1 CDS rpsE NC_009881.1 905227 905757 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(905227..905757) Rickettsia akari str. Hartford 5644627 YP_001493767.1 CDS rplR NC_009881.1 905775 906131 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(905775..906131) Rickettsia akari str. Hartford 5644628 YP_001493768.1 CDS rplF NC_009881.1 906147 906680 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(906147..906680) Rickettsia akari str. Hartford 5644629 YP_001493769.1 CDS rpsH NC_009881.1 906690 907088 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(906690..907088) Rickettsia akari str. Hartford 5644630 YP_001493770.1 CDS rpsN NC_009881.1 907108 907413 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(907108..907413) Rickettsia akari str. Hartford 5644631 YP_001493771.1 CDS rplE NC_009881.1 907431 907970 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(907431..907970) Rickettsia akari str. Hartford 5644632 YP_001493772.1 CDS rplX NC_009881.1 907970 908299 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(907970..908299) Rickettsia akari str. Hartford 5644633 YP_001493773.1 CDS rplN NC_009881.1 908300 908668 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(908300..908668) Rickettsia akari str. Hartford 5644634 YP_001493774.1 CDS rpsQ NC_009881.1 908743 908976 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(908743..908976) Rickettsia akari str. Hartford 5645852 YP_001493775.1 CDS rpmC NC_009881.1 908978 909193 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(908978..909193) Rickettsia akari str. Hartford 5645853 YP_001493776.1 CDS rplP NC_009881.1 909186 909596 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(909186..909596) Rickettsia akari str. Hartford 5645854 YP_001493777.1 CDS rpsC NC_009881.1 909611 910264 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(909611..910264) Rickettsia akari str. Hartford 5645855 YP_001493778.1 CDS rplV NC_009881.1 910266 910625 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(910266..910625) Rickettsia akari str. Hartford 5645856 YP_001493779.1 CDS rpsS NC_009881.1 910634 910912 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(910634..910912) Rickettsia akari str. Hartford 5645857 YP_001493780.1 CDS rplB NC_009881.1 910937 911758 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(910937..911758) Rickettsia akari str. Hartford 5645858 YP_001493781.1 CDS rplW NC_009881.1 911759 912055 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(911759..912055) Rickettsia akari str. Hartford 5645859 YP_001493782.1 CDS rplD NC_009881.1 912052 912675 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(912052..912675) Rickettsia akari str. Hartford 5645306 YP_001493783.1 CDS rplC NC_009881.1 912952 913599 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(912952..913599) Rickettsia akari str. Hartford 5645307 YP_001493784.1 CDS rpsJ NC_009881.1 913600 913917 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(913600..913917) Rickettsia akari str. Hartford 5645308 YP_001493785.1 CDS A1C_05115 NC_009881.1 914013 915200 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(914013..915200) Rickettsia akari str. Hartford 5645309 YP_001493786.1 CDS A1C_05120 NC_009881.1 915772 916506 D COG0566 rRNA methylases; tRNA/rRNA methyltransferase 915772..916506 Rickettsia akari str. Hartford 5645312 YP_001493787.1 CDS A1C_05125 NC_009881.1 916727 917056 D hypothetical protein 916727..917056 Rickettsia akari str. Hartford 5644642 YP_001493788.1 CDS fumC NC_009881.1 917053 918444 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 917053..918444 Rickettsia akari str. Hartford 5644643 YP_001493789.1 CDS A1C_05135 NC_009881.1 918542 918790 D COG4118 Antitoxin of toxin-antitoxin stability system; antitoxin of toxin-antitoxin system Phd 918542..918790 Rickettsia akari str. Hartford 5644644 YP_001493790.1 CDS A1C_05140 NC_009881.1 919059 919262 D toxin of toxin-antitoxin system 919059..919262 Rickettsia akari str. Hartford 5644645 YP_001493791.1 CDS A1C_05145 NC_009881.1 919450 920820 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 919450..920820 Rickettsia akari str. Hartford 5644646 YP_001493792.1 CDS A1C_05150 NC_009881.1 920817 920936 D hypothetical protein 920817..920936 Rickettsia akari str. Hartford 5644647 YP_001493793.1 CDS A1C_05165 NC_009881.1 921913 922047 D COG4574 Serine protease inhibitor ecotin; ecotin 921913..922047 Rickettsia akari str. Hartford 5644648 YP_001493794.1 CDS A1C_05170 NC_009881.1 922305 922877 R COG0694 Thioredoxin-like proteins and domains; hypothetical protein complement(922305..922877) Rickettsia akari str. Hartford 5645387 YP_001493795.1 CDS A1C_05175 NC_009881.1 922940 923773 R COG0477 Permeases of the major facilitator superfamily; AmpG protein complement(922940..923773) Rickettsia akari str. Hartford 5645388 YP_001493796.1 CDS A1C_05180 NC_009881.1 923835 923981 D hypothetical protein 923835..923981 Rickettsia akari str. Hartford 5645389 YP_001493797.1 CDS A1C_05185 NC_009881.1 924356 925588 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlE complement(924356..925588) Rickettsia akari str. Hartford 5645390 YP_001493798.1 CDS A1C_05190 NC_009881.1 926264 926476 R COG1278 Cold shock proteins; cold shock-like protein complement(926264..926476) Rickettsia akari str. Hartford 5645391 YP_001493799.1 CDS ksgA NC_009881.1 926593 926721 D dimethyladenosine transferase 926593..926721 Rickettsia akari str. Hartford 5645392 YP_001493800.1 CDS ksgA NC_009881.1 927592 928413 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(927592..928413) Rickettsia akari str. Hartford 5645394 YP_001493801.1 CDS A1C_05205 NC_009881.1 928548 929438 R COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein complement(928548..929438) Rickettsia akari str. Hartford 5644956 YP_001493802.1 CDS A1C_05210 NC_009881.1 929606 931702 R COG1452 Organic solvent tolerance protein OstA; hypothetical protein complement(929606..931702) Rickettsia akari str. Hartford 5644957 YP_001493803.1 CDS A1C_05215 NC_009881.1 931713 931907 D hypothetical protein 931713..931907 Rickettsia akari str. Hartford 5644958 YP_001493804.1 CDS xseA NC_009881.1 932036 933370 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 932036..933370 Rickettsia akari str. Hartford 5644959 YP_001493805.1 CDS A1C_05225 NC_009881.1 933449 935017 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; hypothetical protein 933449..935017 Rickettsia akari str. Hartford 5644960 YP_001493806.1 CDS A1C_05230 NC_009881.1 935014 935796 D COG0708 Exonuclease III; exodeoxyribonuclease III 935014..935796 Rickettsia akari str. Hartford 5644961 YP_001493807.1 CDS A1C_05235 NC_009881.1 935994 936260 D COG4095 Uncharacterized conserved protein; hypothetical protein 935994..936260 Rickettsia akari str. Hartford 5644962 YP_001493808.1 CDS engA NC_009881.1 936263 937606 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 936263..937606 Rickettsia akari str. Hartford 5645372 YP_001493809.1 CDS A1C_05245 NC_009881.1 937614 937832 R COG1373 Predicted ATPase (AAA+ superfamily); ATPase complement(937614..937832) Rickettsia akari str. Hartford 5645373 YP_001493810.1 CDS A1C_05250 NC_009881.1 938210 938515 R hypothetical protein complement(938210..938515) Rickettsia akari str. Hartford 5645374 YP_001493811.1 CDS A1C_05255 NC_009881.1 938514 938696 D hypothetical protein 938514..938696 Rickettsia akari str. Hartford 5645375 YP_001493812.1 CDS A1C_05260 NC_009881.1 938746 940182 R COG0661 Predicted unusual protein kinase; 2-polyprenylphenol 6-hydroxylase complement(938746..940182) Rickettsia akari str. Hartford 5645376 YP_001493813.1 CDS ubiE NC_009881.1 940179 940925 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(940179..940925) Rickettsia akari str. Hartford 5645377 YP_001493814.1 CDS A1C_05270 NC_009881.1 941119 941274 R hypothetical protein complement(941119..941274) Rickettsia akari str. Hartford 5645378 YP_001493815.1 CDS A1C_05275 NC_009881.1 941271 941336 R hypothetical protein complement(941271..941336) Rickettsia akari str. Hartford 5645379 YP_001493816.1 CDS A1C_05290 NC_009881.1 942402 942605 D COG0836 Mannose-1-phosphate guanylyltransferase; hypothetical protein 942402..942605 Rickettsia akari str. Hartford 5645744 YP_001493817.1 CDS A1C_05295 NC_009881.1 943192 943683 D COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanylyltransferase 943192..943683 Rickettsia akari str. Hartford 5645745 YP_001493818.1 CDS A1C_05300 NC_009881.1 944152 944400 D hypothetical protein 944152..944400 Rickettsia akari str. Hartford 5645746 YP_001493819.1 CDS A1C_05305 NC_009881.1 944984 946237 R COG4553 Poly-beta-hydroxyalkanoate depolymerase; Poly-beta-hydroxyalkanoate depolymerase complement(944984..946237) Rickettsia akari str. Hartford 5645747 YP_001493820.1 CDS A1C_05320 NC_009881.1 947144 947380 R hypothetical protein complement(947144..947380) Rickettsia akari str. Hartford 5645748 YP_001493821.1 CDS A1C_05325 NC_009881.1 947655 948404 R COG0084 Mg-dependent DNase; deoxyribonuclease complement(947655..948404) Rickettsia akari str. Hartford 5645749 YP_001493822.1 CDS A1C_05330 NC_009881.1 948688 950226 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(948688..950226) Rickettsia akari str. Hartford 5645750 YP_001493823.1 CDS tmk NC_009881.1 950223 950834 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(950223..950834) Rickettsia akari str. Hartford 5645751 YP_001493824.1 CDS A1C_05340 NC_009881.1 951095 952375 D COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter 951095..952375 Rickettsia akari str. Hartford 5645424 YP_001493825.1 CDS ubiA NC_009881.1 952630 953472 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase complement(952630..953472) Rickettsia akari str. Hartford 5645425 YP_001493826.1 CDS valS NC_009881.1 954786 957224 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 954786..957224 Rickettsia akari str. Hartford 5645426 YP_001493827.1 CDS A1C_05400 NC_009881.1 959496 960782 D COG1322 Uncharacterized protein conserved in bacteria; hypothetical protein 959496..960782 Rickettsia akari str. Hartford 5645427 YP_001493828.1 CDS A1C_05405 NC_009881.1 960943 961119 R hypothetical protein complement(960943..961119) Rickettsia akari str. Hartford 5645428 YP_001493829.1 CDS A1C_05410 NC_009881.1 961311 961763 R hypothetical protein complement(961311..961763) Rickettsia akari str. Hartford 5645429 YP_001493830.1 CDS A1C_05415 NC_009881.1 961735 962040 R hypothetical protein complement(961735..962040) Rickettsia akari str. Hartford 5645430 YP_001493831.1 CDS A1C_05420 NC_009881.1 962388 962729 R hypothetical protein complement(962388..962729) Rickettsia akari str. Hartford 5645431 YP_001493832.1 CDS A1C_05435 NC_009881.1 963899 963985 D hypothetical protein 963899..963985 Rickettsia akari str. Hartford 5645830 YP_001493833.1 CDS A1C_05440 NC_009881.1 963986 964234 D hypothetical protein 963986..964234 Rickettsia akari str. Hartford 5645831 YP_001493834.1 CDS clpX NC_009881.1 964545 965822 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(964545..965822) Rickettsia akari str. Hartford 5645832 YP_001493835.1 CDS A1C_05450 NC_009881.1 965889 966440 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-alanine acetyltransferase complement(965889..966440) Rickettsia akari str. Hartford 5645833 YP_001493836.1 CDS A1C_05455 NC_009881.1 966574 967257 R COG0603 Predicted PP-loop superfamily ATPase; trans-regulatory protein ExsB complement(966574..967257) Rickettsia akari str. Hartford 5645834 YP_001493837.1 CDS A1C_05460 NC_009881.1 967232 967345 R hypothetical protein complement(967232..967345) Rickettsia akari str. Hartford 5645835 YP_001493838.1 CDS A1C_05465 NC_009881.1 967463 967597 R COG1598 Uncharacterized conserved protein; hypothetical protein complement(967463..967597) Rickettsia akari str. Hartford 5645836 YP_001493839.1 CDS A1C_05470 NC_009881.1 967620 967751 R hypothetical protein complement(967620..967751) Rickettsia akari str. Hartford 5645837 YP_001493840.1 CDS A1C_05475 NC_009881.1 968152 969858 D COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein 968152..969858 Rickettsia akari str. Hartford 5645125 YP_001493841.1 CDS A1C_05480 NC_009881.1 970187 970435 D hypothetical protein 970187..970435 Rickettsia akari str. Hartford 5645126 YP_001493842.1 CDS A1C_05485 NC_009881.1 970979 972154 D COG0477 Permeases of the major facilitator superfamily; bicyclomycin resistance protein 970979..972154 Rickettsia akari str. Hartford 5645127 YP_001493843.1 CDS A1C_05490 NC_009881.1 972263 973510 D COG4591 ABC-type transport system, involved in lipoprotein release, permease component; lipoprotein releasing system, transmembrane protein 972263..973510 Rickettsia akari str. Hartford 5645128 YP_001493844.1 CDS A1C_05495 NC_009881.1 973503 974168 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; lipoprotein releasing system ATP-binding protein LolD 973503..974168 Rickettsia akari str. Hartford 5645129 YP_001493845.1 CDS A1C_05500 NC_009881.1 974225 975223 D hypothetical protein 974225..975223 Rickettsia akari str. Hartford 5645130 YP_001493846.1 CDS A1C_05505 NC_009881.1 975990 976112 D hypothetical protein 975990..976112 Rickettsia akari str. Hartford 5644984 YP_001493847.1 CDS A1C_05510 NC_009881.1 976332 977597 D COG4536 Putative Mg2+ and Co2+ transporter CorB; hypothetical protein 976332..977597 Rickettsia akari str. Hartford 5644985 YP_001493848.1 CDS A1C_05515 NC_009881.1 977911 979569 D COG1138 Cytochrome c biogenesis factor; cytochrome c-type biogenesis protein CcmF 977911..979569 Rickettsia akari str. Hartford 5644986 YP_001493849.1 CDS A1C_05530 NC_009881.1 980178 980294 R hypothetical protein complement(980178..980294) Rickettsia akari str. Hartford 5644987 YP_001493850.1 CDS A1C_05535 NC_009881.1 981137 986113 R COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain; Outer membrane protein B complement(981137..986113) Rickettsia akari str. Hartford 5644988 YP_001493851.1 CDS A1C_05540 NC_009881.1 986442 987047 R COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein complement(986442..987047) Rickettsia akari str. Hartford 5644989 YP_001493852.1 CDS A1C_05545 NC_009881.1 987469 988458 R COG1472 Beta-glucosidase-related glycosidases; Beta-glucosidase complement(987469..988458) Rickettsia akari str. Hartford 5644990 YP_001493853.1 CDS A1C_05550 NC_009881.1 988511 988807 R COG0789 Predicted transcriptional regulators; hypothetical protein complement(988511..988807) Rickettsia akari str. Hartford 5644991 YP_001493854.1 CDS A1C_05555 NC_009881.1 988794 989084 R COG0776 Bacterial nucleoid DNA-binding protein; integration host factor alpha-subunit complement(988794..989084) Rickettsia akari str. Hartford 5645067 YP_001493855.1 CDS A1C_05560 NC_009881.1 989167 989628 R hypothetical protein complement(989167..989628) Rickettsia akari str. Hartford 5645068 YP_001493856.1 CDS A1C_05565 NC_009881.1 990085 990555 D COG1225 Peroxiredoxin; bacterioferritin comigratory protein 990085..990555 Rickettsia akari str. Hartford 5645069 YP_001493857.1 CDS A1C_05570 NC_009881.1 990657 991529 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(990657..991529) Rickettsia akari str. Hartford 5645070 YP_001493858.1 CDS lpxK NC_009881.1 991492 992469 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(991492..992469) Rickettsia akari str. Hartford 5645071 YP_001493859.1 CDS A1C_05580 NC_009881.1 992692 993597 R COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein complement(992692..993597) Rickettsia akari str. Hartford 5645072 YP_001493860.1 CDS A1C_05585 NC_009881.1 993546 994334 R COG2961 Protein involved in catabolism of external DNA; hypothetical protein complement(993546..994334) Rickettsia akari str. Hartford 5645073 YP_001493861.1 CDS ligA NC_009881.1 994573 994665 R NAD-dependent DNA ligase LigA complement(994573..994665) Rickettsia akari str. Hartford 5645074 YP_001493862.1 CDS ligA NC_009881.1 994917 996986 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(994917..996986) Rickettsia akari str. Hartford 5644750 YP_001493863.1 CDS A1C_05600 NC_009881.1 996973 997167 R hypothetical protein complement(996973..997167) Rickettsia akari str. Hartford 5644751 YP_001493864.1 CDS A1C_05605 NC_009881.1 997168 997395 R COG2161 Antitoxin of toxin-antitoxin stability system; prevent-host-death family protein complement(997168..997395) Rickettsia akari str. Hartford 5644752 YP_001493865.1 CDS tgt NC_009881.1 997444 998529 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(997444..998529) Rickettsia akari str. Hartford 5644753 YP_001493866.1 CDS A1C_05615 NC_009881.1 998763 999047 R hypothetical protein complement(998763..999047) Rickettsia akari str. Hartford 5644754 YP_001493867.1 CDS A1C_05620 NC_009881.1 999325 999447 D hypothetical protein 999325..999447 Rickettsia akari str. Hartford 5644755 YP_001493868.1 CDS A1C_05625 NC_009881.1 999949 1001256 R hypothetical protein complement(999949..1001256) Rickettsia akari str. Hartford 5644756 YP_001493869.1 CDS trmE NC_009881.1 1001597 1002934 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(1001597..1002934) Rickettsia akari str. Hartford 5644757 YP_001493870.1 CDS A1C_05635 NC_009881.1 1003006 1007754 D COG2902 NAD-specific glutamate dehydrogenase; NAD-specific glutamate dehydrogenase 1003006..1007754 Rickettsia akari str. Hartford 5645488 YP_001493871.1 CDS A1C_05640 NC_009881.1 1008135 1008338 D hypothetical protein 1008135..1008338 Rickettsia akari str. Hartford 5645489 YP_001493872.1 CDS A1C_05645 NC_009881.1 1008341 1008658 D COG3027 Uncharacterized protein conserved in bacteria; hypothetical protein 1008341..1008658 Rickettsia akari str. Hartford 5645490 YP_001493873.1 CDS A1C_05650 NC_009881.1 1008636 1008758 D hypothetical protein 1008636..1008758 Rickettsia akari str. Hartford 5645491 YP_001493874.1 CDS A1C_05655 NC_009881.1 1009019 1010290 D COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter 1009019..1010290 Rickettsia akari str. Hartford 5645492 YP_001493875.1 CDS A1C_05660 NC_009881.1 1010392 1010643 D transcriptional regulator 1010392..1010643 Rickettsia akari str. Hartford 5645493 YP_001493876.1 CDS A1C_05665 NC_009881.1 1010624 1010776 D PilT domain-containing protein 1010624..1010776 Rickettsia akari str. Hartford 5645494 YP_001493877.1 CDS A1C_05670 NC_009881.1 1011233 1011487 R COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; hypothetical protein complement(1011233..1011487) Rickettsia akari str. Hartford 5645495 YP_001493878.1 CDS A1C_05675 NC_009881.1 1011534 1011869 R COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; hypothetical protein complement(1011534..1011869) Rickettsia akari str. Hartford 5644794 YP_001493879.1 CDS A1C_05680 NC_009881.1 1011960 1012454 R COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; hypothetical protein complement(1011960..1012454) Rickettsia akari str. Hartford 5644795 YP_001493880.1 CDS A1C_05685 NC_009881.1 1012866 1014071 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(1012866..1014071) Rickettsia akari str. Hartford 5644796 YP_001493881.1 CDS rpmA NC_009881.1 1014313 1014573 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1014313..1014573) Rickettsia akari str. Hartford 5644797 YP_001493882.1 CDS rplU NC_009881.1 1014598 1014915 R COG0261 Ribosomal protein L21; 50S ribosomal protein L21 complement(1014598..1014915) Rickettsia akari str. Hartford 5644798 YP_001493883.1 CDS A1C_05700 NC_009881.1 1015132 1015734 R COG1267 Phosphatidylglycerophosphatase A and related proteins; phosphatidylglycerophosphatase A complement(1015132..1015734) Rickettsia akari str. Hartford 5644799 YP_001493884.1 CDS tatA NC_009881.1 1015813 1015974 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 1015813..1015974 Rickettsia akari str. Hartford 5644800 YP_001493885.1 CDS A1C_05710 NC_009881.1 1016097 1017119 R ABC transporter substrate-binding protein complement(1016097..1017119) Rickettsia akari str. Hartford 5644801 YP_001493886.1 CDS A1C_05715 NC_009881.1 1017240 1018076 D COG0313 Predicted methyltransferases; hypothetical protein 1017240..1018076 Rickettsia akari str. Hartford 5645351 YP_001493887.1 CDS A1C_05720 NC_009881.1 1018414 1018503 D hypothetical protein 1018414..1018503 Rickettsia akari str. Hartford 5645352 YP_001493888.1 CDS A1C_05725 NC_009881.1 1018958 1019065 D hypothetical protein 1018958..1019065 Rickettsia akari str. Hartford 5645353 YP_001493889.1 CDS A1C_05730 NC_009881.1 1019148 1019399 R COG5510 Predicted small secreted protein; hypothetical protein complement(1019148..1019399) Rickettsia akari str. Hartford 5645354 YP_001493890.1 CDS A1C_05735 NC_009881.1 1019479 1020165 R COG0177 Predicted EndoIII-related endonuclease; endonuclease III complement(1019479..1020165) Rickettsia akari str. Hartford 5645355 YP_001493891.1 CDS A1C_05740 NC_009881.1 1020215 1020529 D COG0278 Glutaredoxin-related protein; glutaredoxin-like protein grla 1020215..1020529 Rickettsia akari str. Hartford 5645356 YP_001493892.1 CDS A1C_05745 NC_009881.1 1020641 1021285 D COG0400 Predicted esterase; Serine esterase 1020641..1021285 Rickettsia akari str. Hartford 5645357 YP_001493893.1 CDS A1C_05750 NC_009881.1 1021347 1021541 D hypothetical protein 1021347..1021541 Rickettsia akari str. Hartford 5645358 YP_001493894.1 CDS A1C_05755 NC_009881.1 1021547 1021672 D DNA modification methylase 1021547..1021672 Rickettsia akari str. Hartford 5645817 YP_001493895.1 CDS A1C_05760 NC_009881.1 1021800 1021934 D COG0863 DNA modification methylase; DNA modification methylase-like protein 1021800..1021934 Rickettsia akari str. Hartford 5645818 YP_001493896.1 CDS A1C_05765 NC_009881.1 1022193 1022354 D hypothetical protein 1022193..1022354 Rickettsia akari str. Hartford 5645819 YP_001493897.1 CDS glyA NC_009881.1 1022369 1023631 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1022369..1023631 Rickettsia akari str. Hartford 5645820 YP_001493898.1 CDS A1C_05775 NC_009881.1 1023624 1024517 D catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1023624..1024517 Rickettsia akari str. Hartford 5645821 YP_001493899.1 CDS A1C_05780 NC_009881.1 1024757 1024987 D hypothetical protein 1024757..1024987 Rickettsia akari str. Hartford 5645822 YP_001493900.1 CDS A1C_05785 NC_009881.1 1024974 1025294 D COG2337 Growth inhibitor; PemK-like growth inhibitor 1024974..1025294 Rickettsia akari str. Hartford 5645823 YP_001493901.1 CDS A1C_05790 NC_009881.1 1025321 1025824 D COG0319 Predicted metal-dependent hydrolase; putative metalloprotease 1025321..1025824 Rickettsia akari str. Hartford 5645824 YP_001493902.1 CDS A1C_05795 NC_009881.1 1025841 1026746 D COG1253 Hemolysins and related proteins containing CBS domains; hemolysin C 1025841..1026746 Rickettsia akari str. Hartford 5644786 YP_001493903.1 CDS A1C_05800 NC_009881.1 1026808 1026924 R hypothetical protein complement(1026808..1026924) Rickettsia akari str. Hartford 5644787 YP_001493904.1 CDS A1C_05805 NC_009881.1 1027209 1027406 R COG1943 Transposase and inactivated derivatives; transposase IS200-family protein complement(1027209..1027406) Rickettsia akari str. Hartford 5644788 YP_001493905.1 CDS A1C_05810 NC_009881.1 1028688 1030130 R COG3202 ATP/ADP translocase; ADP,ATP carrier protein complement(1028688..1030130) Rickettsia akari str. Hartford 5644789 YP_001493906.1 CDS A1C_05815 NC_009881.1 1030648 1031613 D COG3243 Poly(3-hydroxyalkanoate) synthetase; Poly-beta-hydroxybutyrate polymerase 1030648..1031613 Rickettsia akari str. Hartford 5644790 YP_001493907.1 CDS A1C_05820 NC_009881.1 1031762 1032940 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1031762..1032940 Rickettsia akari str. Hartford 5644791 YP_001493908.1 CDS A1C_05825 NC_009881.1 1033207 1033617 R hypothetical protein complement(1033207..1033617) Rickettsia akari str. Hartford 5644792 YP_001493909.1 CDS A1C_05830 NC_009881.1 1034054 1034269 D hypothetical protein 1034054..1034269 Rickettsia akari str. Hartford 5644793 YP_001493910.1 CDS A1C_05835 NC_009881.1 1034961 1035242 D hypothetical protein 1034961..1035242 Rickettsia akari str. Hartford 5644743 YP_001493911.1 CDS A1C_05840 NC_009881.1 1035829 1036053 R hypothetical protein complement(1035829..1036053) Rickettsia akari str. Hartford 5644745 YP_001493912.1 CDS A1C_05845 NC_009881.1 1036650 1037594 R COG0331 (acyl-carrier-protein) S-malonyltransferase; acyl-carrier-protein S-malonyltransferase complement(1036650..1037594) Rickettsia akari str. Hartford 5644746 YP_001493913.1 CDS A1C_05850 NC_009881.1 1039676 1042132 R COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); ATP-dependent helicase complement(1039676..1042132) Rickettsia akari str. Hartford 5644747 YP_001493914.1 CDS A1C_05855 NC_009881.1 1042184 1042804 R COG3346 Uncharacterized conserved protein; surfeit locus protein 1 complement(1042184..1042804) Rickettsia akari str. Hartford 5644748 YP_001493915.1 CDS A1C_05860 NC_009881.1 1043059 1043748 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1043059..1043748) Rickettsia akari str. Hartford 5644749 YP_001493916.1 CDS coaE NC_009881.1 1043994 1044569 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(1043994..1044569) Rickettsia akari str. Hartford 5645045 YP_001493917.1 CDS A1C_05870 NC_009881.1 1044563 1045375 R COG3494 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1044563..1045375) Rickettsia akari str. Hartford 5645046 YP_001493918.1 CDS A1C_05875 NC_009881.1 1046159 1046632 D COG3814 Uncharacterized protein conserved in bacteria; hypothetical protein 1046159..1046632 Rickettsia akari str. Hartford 5645047 YP_001493919.1 CDS rnhA NC_009881.1 1046642 1047100 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1046642..1047100 Rickettsia akari str. Hartford 5645048 YP_001493920.1 CDS A1C_05885 NC_009881.1 1047088 1047387 D COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit; hypothetical protein 1047088..1047387 Rickettsia akari str. Hartford 5645049 YP_001493921.1 CDS A1C_05890 NC_009881.1 1047456 1047905 D COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; ABC transporter substrate binding protein 1047456..1047905 Rickettsia akari str. Hartford 5645050 YP_001493922.1 CDS A1C_05895 NC_009881.1 1048256 1048351 D hypothetical protein 1048256..1048351 Rickettsia akari str. Hartford 5645051 YP_001493923.1 CDS A1C_05900 NC_009881.1 1048480 1048665 D COG0477 Permeases of the major facilitator superfamily; MFS type sugar transporter 1048480..1048665 Rickettsia akari str. Hartford 5645052 YP_001493924.1 CDS A1C_05905 NC_009881.1 1049147 1049482 R COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein complement(1049147..1049482) Rickettsia akari str. Hartford 5645504 YP_001493925.1 CDS A1C_05910 NC_009881.1 1049492 1049626 R hypothetical protein complement(1049492..1049626) Rickettsia akari str. Hartford 5645505 YP_001493926.1 CDS A1C_05915 NC_009881.1 1051217 1051399 R hypothetical protein complement(1051217..1051399) Rickettsia akari str. Hartford 5645506 YP_001493927.1 CDS A1C_05920 NC_009881.1 1051517 1051963 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(1051517..1051963) Rickettsia akari str. Hartford 5645507 YP_001493928.1 CDS A1C_05925 NC_009881.1 1052410 1052547 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(1052410..1052547) Rickettsia akari str. Hartford 5645508 YP_001493929.1 CDS recA NC_009881.1 1052846 1053934 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1052846..1053934 Rickettsia akari str. Hartford 5645509 YP_001493930.1 CDS fabG NC_009881.1 1053927 1054652 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1053927..1054652 Rickettsia akari str. Hartford 5645510 YP_001493931.1 CDS acpP NC_009881.1 1054818 1055063 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1054818..1055063 Rickettsia akari str. Hartford 5645511 YP_001493932.1 CDS A1C_05945 NC_009881.1 1055099 1056379 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1055099..1056379 Rickettsia akari str. Hartford 5645262 YP_001493933.1 CDS A1C_05960 NC_009881.1 1057827 1058924 D hypothetical protein 1057827..1058924 Rickettsia akari str. Hartford 5645263 YP_001493934.1 CDS A1C_05965 NC_009881.1 1058954 1059190 D hypothetical protein 1058954..1059190 Rickettsia akari str. Hartford 5645264 YP_001493935.1 CDS A1C_05970 NC_009881.1 1059564 1059752 R COG1373 Predicted ATPase (AAA+ superfamily); ATPase complement(1059564..1059752) Rickettsia akari str. Hartford 5645265 YP_001493936.1 CDS A1C_05975 NC_009881.1 1059745 1059927 R COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein complement(1059745..1059927) Rickettsia akari str. Hartford 5645266 YP_001493937.1 CDS A1C_05980 NC_009881.1 1060116 1060235 R COG1373 Predicted ATPase (AAA+ superfamily); ATPase complement(1060116..1060235) Rickettsia akari str. Hartford 5645267 YP_001493938.1 CDS gmk NC_009881.1 1060517 1061095 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1060517..1061095) Rickettsia akari str. Hartford 5645268 YP_001493939.1 CDS A1C_05990 NC_009881.1 1061224 1061460 R COG1396 Predicted transcriptional regulators; hypothetical protein complement(1061224..1061460) Rickettsia akari str. Hartford 5645269 YP_001493940.1 CDS A1C_05995 NC_009881.1 1062033 1062872 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(1062033..1062872) Rickettsia akari str. Hartford 5644678 YP_001493941.1 CDS A1C_06000 NC_009881.1 1062875 1063915 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(1062875..1063915) Rickettsia akari str. Hartford 5644679 YP_001493942.1 CDS A1C_06005 NC_009881.1 1064125 1065213 R COG0795 Predicted permeases; hypothetical protein complement(1064125..1065213) Rickettsia akari str. Hartford 5644680 YP_001493943.1 CDS A1C_06010 NC_009881.1 1065617 1066084 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; peptidoglycan-associated lipoprotein complement(1065617..1066084) Rickettsia akari str. Hartford 5644682 YP_001493944.1 CDS A1C_06015 NC_009881.1 1066419 1067372 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(1066419..1067372) Rickettsia akari str. Hartford 5644683 YP_001493945.1 CDS rpmF NC_009881.1 1067380 1067580 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(1067380..1067580) Rickettsia akari str. Hartford 5644684 YP_001493946.1 CDS A1C_06025 NC_009881.1 1067676 1068149 D COG2913 Small protein A (tmRNA-binding); hypothetical protein 1067676..1068149 Rickettsia akari str. Hartford 5645803 YP_001493947.1 CDS A1C_06030 NC_009881.1 1068315 1069226 D COG0552 Signal recognition particle GTPase; Signal recognition particle-docking protein FtsY 1068315..1069226 Rickettsia akari str. Hartford 5645804 YP_001493948.1 CDS A1C_06035 NC_009881.1 1069423 1072041 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1069423..1072041 Rickettsia akari str. Hartford 5645805 YP_001493949.1 CDS A1C_06040 NC_009881.1 1072655 1073797 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1072655..1073797 Rickettsia akari str. Hartford 5645806 YP_001493950.1 CDS A1C_06045 NC_009881.1 1074278 1074622 D hypothetical protein 1074278..1074622 Rickettsia akari str. Hartford 5645807 YP_001493951.1 CDS dnaE NC_009881.1 1075171 1078728 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(1075171..1078728) Rickettsia akari str. Hartford 5645808 YP_001493952.1 CDS A1C_06055 NC_009881.1 1078877 1080181 R COG1004 Predicted UDP-glucose 6-dehydrogenase; UDP-glucose 6-dehydrogenase complement(1078877..1080181) Rickettsia akari str. Hartford 5645809 YP_001493953.1 CDS A1C_06060 NC_009881.1 1080430 1082943 D hypothetical protein 1080430..1082943 Rickettsia akari str. Hartford 5645810 YP_001493954.1 CDS A1C_06065 NC_009881.1 1082953 1084218 D COG0477 Permeases of the major facilitator superfamily; AmpG protein 1082953..1084218 Rickettsia akari str. Hartford 5644840 YP_001493955.1 CDS A1C_06070 NC_009881.1 1084285 1085040 D COG0805 Sec-independent protein secretion pathway component TatC; Sec-independent protein translocase protein TatC 1084285..1085040 Rickettsia akari str. Hartford 5644841 YP_001493956.1 CDS A1C_06075 NC_009881.1 1085018 1086295 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1085018..1086295 Rickettsia akari str. Hartford 5644842 YP_001493957.1 CDS A1C_06080 NC_009881.1 1086555 1088987 D COG3451 Type IV secretory pathway, VirB4 components; Type IV secretion/conjugal transfer ATPase, VirB4 family protein 1086555..1088987 Rickettsia akari str. Hartford 5644843 YP_001493958.1 CDS A1C_06085 NC_009881.1 1089243 1092779 D hypothetical protein 1089243..1092779 Rickettsia akari str. Hartford 5644844 YP_001493959.1 CDS A1C_06090 NC_009881.1 1092784 1093689 D COG0861 Membrane protein TerC, possibly involved in tellurium resistance; tellurium resistance protein TerC 1092784..1093689 Rickettsia akari str. Hartford 5644845 YP_001493960.1 CDS A1C_06095 NC_009881.1 1093732 1094445 D COG3637 Opacity protein and related surface antigens; hypothetical protein 1093732..1094445 Rickettsia akari str. Hartford 5644846 YP_001493961.1 CDS A1C_06100 NC_009881.1 1094611 1096266 D COG0500 SAM-dependent methyltransferases; hypothetical protein 1094611..1096266 Rickettsia akari str. Hartford 5644847 YP_001493962.1 CDS A1C_06105 NC_009881.1 1096432 1097049 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1096432..1097049 Rickettsia akari str. Hartford 5644619 YP_001493963.1 CDS A1C_06110 NC_009881.1 1097042 1097356 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1097042..1097356 Rickettsia akari str. Hartford 5644620 YP_001493964.1 CDS A1C_06115 NC_009881.1 1097358 1099328 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1097358..1099328 Rickettsia akari str. Hartford 5644621 YP_001493965.1 CDS A1C_06120 NC_009881.1 1099479 1100960 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1099479..1100960 Rickettsia akari str. Hartford 5644622 YP_001493966.1 CDS A1C_06125 NC_009881.1 1100961 1101065 D hypothetical protein 1100961..1101065 Rickettsia akari str. Hartford 5644623 YP_001493967.1 CDS A1C_06130 NC_009881.1 1101314 1101934 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1101314..1101934 Rickettsia akari str. Hartford 5644624 YP_001493968.1 CDS A1C_06135 NC_009881.1 1102527 1103006 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(1102527..1103006) Rickettsia akari str. Hartford 5644625 YP_001493969.1 CDS A1C_06140 NC_009881.1 1103224 1103394 D COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); NADH dehydrogenase subunit H 1103224..1103394 Rickettsia akari str. Hartford 5644626 YP_001493970.1 CDS A1C_06145 NC_009881.1 1103533 1104552 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(1103533..1104552) Rickettsia akari str. Hartford 5644720 YP_001493971.1 CDS A1C_06150 NC_009881.1 1104700 1106715 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(1104700..1106715) Rickettsia akari str. Hartford 5644721 YP_001493972.1 CDS A1C_06155 NC_009881.1 1106717 1107073 R COG3671 Predicted membrane protein; hypothetical protein complement(1106717..1107073) Rickettsia akari str. Hartford 5644722 YP_001493973.1 CDS A1C_06160 NC_009881.1 1107088 1107324 R hypothetical protein complement(1107088..1107324) Rickettsia akari str. Hartford 5644723 YP_001493974.1 CDS A1C_06165 NC_009881.1 1107396 1107557 R hypothetical protein complement(1107396..1107557) Rickettsia akari str. Hartford 5644724 YP_001493975.1 CDS A1C_06180 NC_009881.1 1107958 1110594 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1107958..1110594) Rickettsia akari str. Hartford 5644725 YP_001493976.1 CDS atpC NC_009881.1 1110790 1111128 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1110790..1111128) Rickettsia akari str. Hartford 5644726 YP_001493977.1 CDS A1C_06190 NC_009881.1 1111317 1112738 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1111317..1112738) Rickettsia akari str. Hartford 5644727 YP_001493978.1 CDS A1C_06195 NC_009881.1 1112821 1113687 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1112821..1113687) Rickettsia akari str. Hartford 5645767 YP_001493979.1 CDS A1C_06200 NC_009881.1 1113777 1115315 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1113777..1115315) Rickettsia akari str. Hartford 5645768 YP_001493980.1 CDS A1C_06205 NC_009881.1 1115446 1116000 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1115446..1116000) Rickettsia akari str. Hartford 5645769 YP_001493981.1 CDS A1C_06210 NC_009881.1 1115997 1117376 R Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1115997..1117376) Rickettsia akari str. Hartford 5645770 YP_001493982.1 CDS A1C_06215 NC_009881.1 1117480 1117908 R COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Strees induced DNA-binding protein complement(1117480..1117908) Rickettsia akari str. Hartford 5645771 YP_001493983.1 CDS A1C_06220 NC_009881.1 1118207 1118395 R hypothetical protein complement(1118207..1118395) Rickettsia akari str. Hartford 5645772 YP_001493984.1 CDS A1C_06225 NC_009881.1 1118604 1119695 D hypothetical protein 1118604..1119695 Rickettsia akari str. Hartford 5645773 YP_001493985.1 CDS A1C_06240 NC_009881.1 1120674 1123049 R COG5009 Membrane carboxypeptidase/penicillin-binding protein; 1A family penicillin-binding protein complement(1120674..1123049) Rickettsia akari str. Hartford 5645774 YP_001493986.1 CDS A1C_06245 NC_009881.1 1123053 1124390 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(1123053..1124390) Rickettsia akari str. Hartford 5645544 YP_001493987.1 CDS A1C_06250 NC_009881.1 1124495 1124644 R hypothetical protein complement(1124495..1124644) Rickettsia akari str. Hartford 5645545 YP_001493988.1 CDS A1C_06255 NC_009881.1 1124933 1125109 R hypothetical protein complement(1124933..1125109) Rickettsia akari str. Hartford 5645546 YP_001493989.1 CDS A1C_06270 NC_009881.1 1126182 1126661 R COG3807 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1126182..1126661) Rickettsia akari str. Hartford 5645547 YP_001493990.1 CDS A1C_06275 NC_009881.1 1126654 1128381 R COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein kefB complement(1126654..1128381) Rickettsia akari str. Hartford 5645548 YP_001493991.1 CDS A1C_06280 NC_009881.1 1128378 1128704 R COG0799 Uncharacterized homolog of plant Iojap protein; Iojap-related protein complement(1128378..1128704) Rickettsia akari str. Hartford 5645549 YP_001493992.1 CDS A1C_06285 NC_009881.1 1128870 1129109 D COG0271 Stress-induced morphogen (activity unknown); hypothetical protein 1128870..1129109 Rickettsia akari str. Hartford 5645550 YP_001493993.1 CDS A1C_06290 NC_009881.1 1129295 1129435 D hypothetical protein 1129295..1129435 Rickettsia akari str. Hartford 5645551 YP_001493994.1 CDS A1C_06295 NC_009881.1 1129551 1129874 D COG1396 Predicted transcriptional regulators; Phage-related transcriptional regulator 1129551..1129874 Rickettsia akari str. Hartford 5644685 YP_001493995.1 CDS infA NC_009881.1 1130725 1130940 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1130725..1130940 Rickettsia akari str. Hartford 5644687 YP_001493996.1 CDS A1C_06305 NC_009881.1 1130952 1131557 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1130952..1131557 Rickettsia akari str. Hartford 5644688 YP_001493997.1 CDS A1C_06310 NC_009881.1 1131856 1132287 R COG1734 DnaK suppressor protein; DnaK suppressor protein complement(1131856..1132287) Rickettsia akari str. Hartford 5644689 YP_001493998.1 CDS xerC NC_009881.1 1132386 1133303 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(1132386..1133303) Rickettsia akari str. Hartford 5644690 YP_001493999.1 CDS A1C_06320 NC_009881.1 1133472 1133951 D phasin family protein 1133472..1133951 Rickettsia akari str. Hartford 5644691 YP_001494000.1 CDS A1C_06325 NC_009881.1 1134110 1134712 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phospholipase D complement(1134110..1134712) Rickettsia akari str. Hartford 5644948 YP_001494001.1 CDS A1C_06330 NC_009881.1 1134805 1136556 R COG3243 Poly(3-hydroxyalkanoate) synthetase; Poly(3-hydroxyalkanoate) synthetase complement(1134805..1136556) Rickettsia akari str. Hartford 5644949 YP_001494002.1 CDS A1C_06335 NC_009881.1 1136638 1138116 R COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; UbiD family decarboxylase complement(1136638..1138116) Rickettsia akari str. Hartford 5644950 YP_001494003.1 CDS A1C_06340 NC_009881.1 1138322 1139896 R COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase complement(1138322..1139896) Rickettsia akari str. Hartford 5644951 YP_001494004.1 CDS A1C_06355 NC_009881.1 1141002 1141208 R hypothetical protein complement(1141002..1141208) Rickettsia akari str. Hartford 5644952 YP_001494005.1 CDS A1C_06360 NC_009881.1 1141269 1141397 R hypothetical protein complement(1141269..1141397) Rickettsia akari str. Hartford 5644953 YP_001494006.1 CDS A1C_06365 NC_009881.1 1141500 1142210 R hypothetical protein complement(1141500..1142210) Rickettsia akari str. Hartford 5644954 YP_001494007.1 CDS A1C_06370 NC_009881.1 1142468 1143022 R outer membrane protein OmpA complement(1142468..1143022) Rickettsia akari str. Hartford 5644955 YP_001494008.1 CDS A1C_06375 NC_009881.1 1142989 1143387 R outer membrane protein OmpA complement(1142989..1143387) Rickettsia akari str. Hartford 5645395 YP_001494009.1 CDS A1C_06380 NC_009881.1 1143539 1143637 R hypothetical protein complement(1143539..1143637) Rickettsia akari str. Hartford 5645396 YP_001494010.1 CDS A1C_06385 NC_009881.1 1143803 1144294 R hypothetical protein complement(1143803..1144294) Rickettsia akari str. Hartford 5645397 YP_001494011.1 CDS A1C_06390 NC_009881.1 1144603 1146840 R COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division protein FtsK complement(1144603..1146840) Rickettsia akari str. Hartford 5645398 YP_001494012.1 CDS A1C_06395 NC_009881.1 1146993 1147784 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1146993..1147784 Rickettsia akari str. Hartford 5645399 YP_001494013.1 CDS A1C_06410 NC_009881.1 1148887 1149870 D COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1148887..1149870 Rickettsia akari str. Hartford 5645400 YP_001494014.1 CDS A1C_06415 NC_009881.1 1149867 1150193 D hypothetical protein 1149867..1150193 Rickettsia akari str. Hartford 5645401 YP_001494015.1 CDS A1C_06420 NC_009881.1 1150629 1151462 R COG3637 Opacity protein and related surface antigens; hypothetical protein complement(1150629..1151462) Rickettsia akari str. Hartford 5645402 YP_001494016.1 CDS A1C_06425 NC_009881.1 1151697 1152371 R COG3637 Opacity protein and related surface antigens; putative outer surface protein complement(1151697..1152371) Rickettsia akari str. Hartford 5645179 YP_001494017.1 CDS A1C_06430 NC_009881.1 1152520 1152849 R COG1146 Ferredoxin; ferredoxin complement(1152520..1152849) Rickettsia akari str. Hartford 5645180 YP_001494018.1 CDS A1C_06435 NC_009881.1 1152854 1153546 R COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; Heme exporter protein C complement(1152854..1153546) Rickettsia akari str. Hartford 5645181 YP_001494019.1 CDS A1C_06440 NC_009881.1 1153755 1154234 R COG0590 Cytosine/adenosine deaminases; cytosine deaminase complement(1153755..1154234) Rickettsia akari str. Hartford 5645182 YP_001494020.1 CDS A1C_06445 NC_009881.1 1154215 1155120 R COG0053 Predicted Co/Zn/Cd cation transporters; cation diffusion facilitator family transporter complement(1154215..1155120) Rickettsia akari str. Hartford 5645183 YP_001494021.1 CDS A1C_06450 NC_009881.1 1155248 1155727 D COG4520 Surface antigen; 17 kD surface antigen 1155248..1155727 Rickettsia akari str. Hartford 5645184 YP_001494022.1 CDS A1C_06455 NC_009881.1 1155882 1156094 D COG1881 Phospholipid-binding protein; hypothetical protein 1155882..1156094 Rickettsia akari str. Hartford 5645185 YP_001494023.1 CDS A1C_06460 NC_009881.1 1156530 1157231 D COG1121 ABC-type Mn/Zn transport systems, ATPase component; Zinc ABC transporter ATP-binding protein 1156530..1157231 Rickettsia akari str. Hartford 5645186 YP_001494024.1 CDS uvrA NC_009881.1 1157234 1160095 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(1157234..1160095) Rickettsia akari str. Hartford 5644897 YP_001494025.1 CDS A1C_06470 NC_009881.1 1160204 1160662 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1160204..1160662 Rickettsia akari str. Hartford 5644898 YP_001494026.1 CDS A1C_06475 NC_009881.1 1160868 1161695 D DAP2-like protein 1160868..1161695 Rickettsia akari str. Hartford 5644899 YP_001494027.1 CDS A1C_06480 NC_009881.1 1161937 1162494 D COG0477 Permeases of the major facilitator superfamily; MFS type sugar transporter 1161937..1162494 Rickettsia akari str. Hartford 5644900 YP_001494028.1 CDS A1C_06485 NC_009881.1 1162724 1162894 D MFS type sugar transporter 1162724..1162894 Rickettsia akari str. Hartford 5644901 YP_001494029.1 CDS A1C_06490 NC_009881.1 1163039 1163143 R hypothetical protein complement(1163039..1163143) Rickettsia akari str. Hartford 5644902 YP_001494030.1 CDS A1C_06495 NC_009881.1 1163344 1163460 R hypothetical protein complement(1163344..1163460) Rickettsia akari str. Hartford 5644903 YP_001494031.1 CDS A1C_06500 NC_009881.1 1163990 1164184 R hypothetical protein complement(1163990..1164184) Rickettsia akari str. Hartford 5644904 YP_001494032.1 CDS A1C_06505 NC_009881.1 1164228 1164338 R hypothetical protein complement(1164228..1164338) Rickettsia akari str. Hartford 5645299 YP_001494033.1 CDS A1C_06510 NC_009881.1 1165200 1165517 D COG1872 Uncharacterized conserved protein; hypothetical protein 1165200..1165517 Rickettsia akari str. Hartford 5645301 YP_001494034.1 CDS A1C_06515 NC_009881.1 1165686 1167551 D molecular chaperone; heat shock protein 90 1165686..1167551 Rickettsia akari str. Hartford 5645302 YP_001494035.1 CDS A1C_06520 NC_009881.1 1167736 1168980 D catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 1167736..1168980 Rickettsia akari str. Hartford 5645303 YP_001494036.1 CDS A1C_06525 NC_009881.1 1169241 1169696 D hypothetical protein 1169241..1169696 Rickettsia akari str. Hartford 5645304 YP_001494037.1 CDS tig NC_009881.1 1170181 1171518 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1170181..1171518 Rickettsia akari str. Hartford 5645305 YP_001494038.1 CDS obgE NC_009881.1 1171732 1172724 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1171732..1172724) Rickettsia akari str. Hartford 5645860 YP_001494039.1 CDS gltA NC_009881.1 1172942 1174249 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(1172942..1174249) Rickettsia akari str. Hartford 5645861 YP_001494040.1 CDS A1C_06545 NC_009881.1 1174616 1174792 R transcriptional regulator complement(1174616..1174792) Rickettsia akari str. Hartford 5645862 YP_001494041.1 CDS A1C_06550 NC_009881.1 1174989 1175978 R COG1573 Uracil-DNA glycosylase; hypothetical protein complement(1174989..1175978) Rickettsia akari str. Hartford 5645863 YP_001494042.1 CDS A1C_06555 NC_009881.1 1175941 1176930 D COG0564 Pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase, RluD subfamily protein 1175941..1176930 Rickettsia akari str. Hartford 5645864 YP_001494043.1 CDS A1C_06560 NC_009881.1 1177943 1178068 D hypothetical protein 1177943..1178068 Rickettsia akari str. Hartford 5645865 YP_001494044.1 CDS A1C_06565 NC_009881.1 1178163 1178429 D COG2337 Growth inhibitor; growth inhibitor 1178163..1178429 Rickettsia akari str. Hartford 5645866 YP_001494045.1 CDS A1C_06570 NC_009881.1 1178414 1179982 D fusion of hemK/trmB; N-terminal HemK domain transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; C-terminal; bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase 1178414..1179982 Rickettsia akari str. Hartford 5645867 YP_001494046.1 CDS A1C_06575 NC_009881.1 1179948 1180886 R COG0009 Putative translation factor (SUA5); hypothetical protein complement(1179948..1180886) Rickettsia akari str. Hartford 5645291 YP_001494047.1 CDS glyS NC_009881.1 1180965 1182953 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1180965..1182953) Rickettsia akari str. Hartford 5645292 YP_001494048.1 CDS glyQ NC_009881.1 1182946 1183815 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1182946..1183815) Rickettsia akari str. Hartford 5645293 YP_001494049.1 CDS A1C_06590 NC_009881.1 1183847 1183981 R COG1487 Predicted nucleic acid-binding protein, contains PIN domain; hypothetical protein complement(1183847..1183981) Rickettsia akari str. Hartford 5645294 YP_001494050.1 CDS A1C_06595 NC_009881.1 1184267 1184896 R COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1184267..1184896) Rickettsia akari str. Hartford 5645295 YP_001494051.1 CDS A1C_06600 NC_009881.1 1184905 1185396 R COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter complement(1184905..1185396) Rickettsia akari str. Hartford 5645296 YP_001494052.1 CDS A1C_06605 NC_009881.1 1185345 1186151 R COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter complement(1185345..1186151) Rickettsia akari str. Hartford 5645297 YP_001494053.1 CDS A1C_06610 NC_009881.1 1186519 1187472 R hypothetical protein complement(1186519..1187472) Rickettsia akari str. Hartford 5645298 YP_001494054.1 CDS A1C_06615 NC_009881.1 1187482 1188120 R COG1474 Cdc6-related protein, AAA superfamily ATPase; hypothetical protein complement(1187482..1188120) Rickettsia akari str. Hartford 5645593 YP_001494055.1 CDS A1C_06620 NC_009881.1 1188374 1189945 R hypothetical protein complement(1188374..1189945) Rickettsia akari str. Hartford 5645594 YP_001494056.1 CDS alaS NC_009881.1 1190166 1192802 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1190166..1192802 Rickettsia akari str. Hartford 5645595 YP_001494057.1 CDS A1C_06630 NC_009881.1 1193016 1193342 R hypothetical protein complement(1193016..1193342) Rickettsia akari str. Hartford 5645596 YP_001494058.1 CDS A1C_06635 NC_009881.1 1193544 1193768 R hypothetical protein complement(1193544..1193768) Rickettsia akari str. Hartford 5645597 YP_001494059.1 CDS truA NC_009881.1 1194006 1194278 R tRNA pseudouridine synthase A complement(1194006..1194278) Rickettsia akari str. Hartford 5645598 YP_001494060.1 CDS A1C_06645 NC_009881.1 1194244 1194474 R hypothetical protein complement(1194244..1194474) Rickettsia akari str. Hartford 5645599 YP_001494061.1 CDS A1C_06650 NC_009881.1 1194517 1194672 R hypothetical protein complement(1194517..1194672) Rickettsia akari str. Hartford 5645600 YP_001494062.1 CDS A1C_06655 NC_009881.1 1194849 1195133 R hypothetical protein complement(1194849..1195133) Rickettsia akari str. Hartford 5645679 YP_001494063.1 CDS truA NC_009881.1 1195282 1196019 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1195282..1196019) Rickettsia akari str. Hartford 5645680 YP_001494064.1 CDS A1C_06665 NC_009881.1 1196228 1198135 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(1196228..1198135) Rickettsia akari str. Hartford 5645681 YP_001494065.1 CDS dnaG NC_009881.1 1198179 1199966 R synthesizes RNA primers at the replication forks; DNA primase complement(1198179..1199966) Rickettsia akari str. Hartford 5645682 YP_001494066.1 CDS A1C_06675 NC_009881.1 1199971 1200585 R COG0170 Dolichol kinase; dolichol kinase complement(1199971..1200585) Rickettsia akari str. Hartford 5645683 YP_001494067.1 CDS greA NC_009881.1 1200875 1201453 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1200875..1201453 Rickettsia akari str. Hartford 5645684 YP_001494068.1 CDS A1C_06685 NC_009881.1 1201620 1202018 R COG3288 NAD/NADP transhydrogenase alpha subunit; NAD(P) transhydrogenase subunit alpha complement(1201620..1202018) Rickettsia akari str. Hartford 5645685 YP_001494069.1 CDS A1C_06690 NC_009881.1 1202095 1203216 R COG3288 NAD/NADP transhydrogenase alpha subunit; NAD(P) transhydrogenase subunit alpha complement(1202095..1203216) Rickettsia akari str. Hartford 5645686 YP_001494070.1 CDS A1C_06695 NC_009881.1 1203285 1203923 D COG2834 Outer membrane lipoprotein-sorting protein; hypothetical protein 1203285..1203923 Rickettsia akari str. Hartford 5644912 YP_001494071.1 CDS A1C_06700 NC_009881.1 1204294 1205823 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; rhe tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1204294..1205823 Rickettsia akari str. Hartford 5644913 YP_001494072.1 CDS A1C_06705 NC_009881.1 1205835 1206158 D COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 1205835..1206158 Rickettsia akari str. Hartford 5644914 YP_001494073.1 CDS A1C_06710 NC_009881.1 1206413 1207108 R COG3577 Predicted aspartyl protease; hypothetical protein complement(1206413..1207108) Rickettsia akari str. Hartford 5644915 YP_001494074.1 CDS A1C_06715 NC_009881.1 1207342 1207644 R COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase AmpC complement(1207342..1207644) Rickettsia akari str. Hartford 5644916 YP_001494075.1 CDS A1C_06720 NC_009881.1 1208235 1208957 R COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein complement(1208235..1208957) Rickettsia akari str. Hartford 5644917 YP_001494076.1 CDS A1C_06725 NC_009881.1 1208961 1209725 R COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; beta-lactamase superfamily hydrolase complement(1208961..1209725) Rickettsia akari str. Hartford 5644918 YP_001494077.1 CDS A1C_06730 NC_009881.1 1209737 1210411 D COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 1209737..1210411 Rickettsia akari str. Hartford 5644919 YP_001494078.1 CDS A1C_06735 NC_009881.1 1210485 1211567 D COG0795 Predicted permeases; hypothetical protein 1210485..1211567 Rickettsia akari str. Hartford 5644589 YP_001494079.1 CDS A1C_06740 NC_009881.1 1211570 1212034 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(1211570..1212034) Rickettsia akari str. Hartford 5644590 YP_001494080.1 CDS A1C_06745 NC_009881.1 1212370 1212645 D succinyl-diaminopimelate desuccinylase 1212370..1212645 Rickettsia akari str. Hartford 5644591 YP_001494081.1 CDS A1C_06750 NC_009881.1 1212663 1213784 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(1212663..1213784) Rickettsia akari str. Hartford 5644592 YP_001494082.1 CDS A1C_06755 NC_009881.1 1213812 1214204 R COG0286 Type I restriction-modification system methyltransferase subunit; Type I restriction-modification system methyltransferase subunit complement(1213812..1214204) Rickettsia akari str. Hartford 5644593 YP_001494083.1 CDS A1C_06760 NC_009881.1 1214328 1214627 R Type I restriction-modification system methyltransferase subunit complement(1214328..1214627) Rickettsia akari str. Hartford 5644594 YP_001494084.1 CDS A1C_06765 NC_009881.1 1214745 1214966 R Type I restriction-modification system methyltransferase subunit complement(1214745..1214966) Rickettsia akari str. Hartford 5644595 YP_001494085.1 CDS A1C_06770 NC_009881.1 1215462 1215668 D COG3004 Na+/H+ antiporter; Na+/H+ antiporter NhaA 1215462..1215668 Rickettsia akari str. Hartford 5644596 YP_001494086.1 CDS A1C_06775 NC_009881.1 1216078 1216323 D COG3004 Na+/H+ antiporter; Na+/H+ antiporter NhaA 1216078..1216323 Rickettsia akari str. Hartford 5645552 YP_001494087.1 CDS A1C_06780 NC_009881.1 1216580 1217104 R COG1434 Uncharacterized conserved protein; hypothetical protein complement(1216580..1217104) Rickettsia akari str. Hartford 5645553 YP_001494088.1 CDS lipB NC_009881.1 1217101 1217730 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1217101..1217730) Rickettsia akari str. Hartford 5645554 YP_001494089.1 CDS A1C_06790 NC_009881.1 1217748 1218494 R COG3023 Negative regulator of beta-lactamase expression; hypothetical protein complement(1217748..1218494) Rickettsia akari str. Hartford 5645555 YP_001494090.1 CDS rpsP NC_009881.1 1218983 1219318 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1218983..1219318) Rickettsia akari str. Hartford 5645557 YP_001494091.1 CDS rpmG NC_009881.1 1219332 1219502 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1219332..1219502) Rickettsia akari str. Hartford 5645558 YP_001494092.1 CDS mutL NC_009881.1 1219680 1221509 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(1219680..1221509) Rickettsia akari str. Hartford 5645208 YP_001494093.1 CDS A1C_06810 NC_009881.1 1221506 1221658 R COG4391 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1221506..1221658) Rickettsia akari str. Hartford 5645209 YP_001494094.1 CDS A1C_06815 NC_009881.1 1221735 1221863 R hypothetical protein complement(1221735..1221863) Rickettsia akari str. Hartford 5645210 YP_001494095.1 CDS A1C_06835 NC_009881.1 1222470 1222736 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1222470..1222736 Rickettsia akari str. Hartford 5645211 YP_001494096.1 CDS A1C_06840 NC_009881.1 1222856 1222975 D hypothetical protein 1222856..1222975 Rickettsia akari str. Hartford 5645212 YP_001494097.1 CDS A1C_06845 NC_009881.1 1223031 1223237 D hypothetical protein 1223031..1223237 Rickettsia akari str. Hartford 5645213 YP_001494098.1 CDS A1C_06850 NC_009881.1 1223234 1223332 D hypothetical protein 1223234..1223332 Rickettsia akari str. Hartford 5645214 YP_001494099.1 CDS A1C_06855 NC_009881.1 1224633 1225904 D COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter 1224633..1225904 Rickettsia akari str. Hartford 5645215 YP_001494100.1 CDS A1C_06860 NC_009881.1 1225888 1226727 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1225888..1226727 Rickettsia akari str. Hartford 5645040 YP_001494101.1 CDS A1C_06865 NC_009881.1 1227044 1227163 R hypothetical protein complement(1227044..1227163) Rickettsia akari str. Hartford 5645041 YP_001494102.1 CDS A1C_06870 NC_009881.1 1228182 1228619 R COG1981 Predicted membrane protein; hypothetical protein complement(1228182..1228619) Rickettsia akari str. Hartford 5645042 YP_001494103.1 CDS hemH NC_009881.1 1228631 1229665 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1228631..1229665) Rickettsia akari str. Hartford 5645043 YP_001494104.1 CDS hemE NC_009881.1 1229658 1230674 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(1229658..1230674) Rickettsia akari str. Hartford 5645044 A1C_t06887 tRNA A1C_t06887 NC_009881.1 37717 37791 R tRNA-Glu complement(37717..37791) Rickettsia akari str. Hartford 5644783 A1C_t06889 tRNA A1C_t06889 NC_009881.1 50002 50077 D tRNA-Phe 50002..50077 Rickettsia akari str. Hartford 5645313 A1C_t06891 tRNA A1C_t06891 NC_009881.1 99887 99961 D tRNA-Thr 99887..99961 Rickettsia akari str. Hartford 5645319 A1C_t06893 tRNA A1C_t06893 NC_009881.1 134966 135042 D tRNA-Met 134966..135042 Rickettsia akari str. Hartford 5645783 A1C_t06895 tRNA A1C_t06895 NC_009881.1 181307 181382 D tRNA-Trp 181307..181382 Rickettsia akari str. Hartford 5645703 A1C_t06897 tRNA A1C_t06897 NC_009881.1 216062 216137 R tRNA-Thr complement(216062..216137) Rickettsia akari str. Hartford 5645142 A1C_t06899 tRNA A1C_t06899 NC_009881.1 324501 324577 D tRNA-Met 324501..324577 Rickettsia akari str. Hartford 5645363 A1C_t06901 tRNA A1C_t06901 NC_009881.1 372215 372289 D tRNA-Asn 372215..372289 Rickettsia akari str. Hartford 5645532 A1C_t06903 tRNA A1C_t06903 NC_009881.1 486454 486528 D tRNA-Cys 486454..486528 Rickettsia akari str. Hartford 5645254 A1C_t06905 tRNA A1C_t06905 NC_009881.1 518097 518172 D tRNA-Lys 518097..518172 Rickettsia akari str. Hartford 5644640 A1C_t06907 tRNA A1C_t06907 NC_009881.1 518187 518263 D tRNA-Ile 518187..518263 Rickettsia akari str. Hartford 5644641 A1C_t06909 tRNA A1C_t06909 NC_009881.1 621146 621222 R tRNA-Asp complement(621146..621222) Rickettsia akari str. Hartford 5644603 A1C_t06911 tRNA A1C_t06911 NC_009881.1 685659 685735 R tRNA-Arg complement(685659..685735) Rickettsia akari str. Hartford 5645439 A1C_t06913 tRNA A1C_t06913 NC_009881.1 700532 700621 D tRNA-Ser 700532..700621 Rickettsia akari str. Hartford 5645813 A1C_t06915 tRNA A1C_t06915 NC_009881.1 701660 701734 R tRNA-Gln complement(701660..701734) Rickettsia akari str. Hartford 5645815 A1C_t06917 tRNA A1C_t06917 NC_009881.1 754090 754177 D tRNA-Ser 754090..754177 Rickettsia akari str. Hartford 5645337 A1C_t06919 tRNA A1C_t06919 NC_009881.1 758993 759068 R tRNA-Ala complement(758993..759068) Rickettsia akari str. Hartford 5645587 A1C_t06921 tRNA A1C_t06921 NC_009881.1 762939 763015 D tRNA-Val 762939..763015 Rickettsia akari str. Hartford 5645591 A1C_t06923 tRNA A1C_t06923 NC_009881.1 769909 769985 D tRNA-Arg 769909..769985 Rickettsia akari str. Hartford 5644816 A1C_t06925 tRNA A1C_t06925 NC_009881.1 803849 803923 R tRNA-Ala complement(803849..803923) Rickettsia akari str. Hartford 5645758 A1C_t06927 tRNA A1C_t06927 NC_009881.1 815875 815961 D tRNA-Leu 815875..815961 Rickettsia akari str. Hartford 5645515 A1C_t06929 tRNA A1C_t06929 NC_009881.1 821120 821194 D tRNA-Gly 821120..821194 Rickettsia akari str. Hartford 5645525 A1C_t06931 tRNA A1C_t06931 NC_009881.1 899801 899876 R tRNA-Val complement(899801..899876) Rickettsia akari str. Hartford 5645880 A1C_t06933 tRNA A1C_t06933 NC_009881.1 915275 915348 R tRNA-Gly complement(915275..915348) Rickettsia akari str. Hartford 5645310 A1C_t06935 tRNA A1C_t06935 NC_009881.1 915511 915596 R tRNA-Tyr complement(915511..915596) Rickettsia akari str. Hartford 5645311 A1C_t06937 tRNA A1C_t06937 NC_009881.1 926868 926953 D tRNA-Leu 926868..926953 Rickettsia akari str. Hartford 5645393 A1C_t06939 tRNA A1C_t06939 NC_009881.1 967939 968015 D tRNA-His 967939..968015 Rickettsia akari str. Hartford 5645124 A1C_t06941 tRNA A1C_t06941 NC_009881.1 1035246 1035337 R tRNA-Ser complement(1035246..1035337) Rickettsia akari str. Hartford 5644744 A1C_t06943 tRNA A1C_t06943 NC_009881.1 1065255 1065331 R tRNA-Met complement(1065255..1065331) Rickettsia akari str. Hartford 5644681 A1C_t06945 tRNA A1C_t06945 NC_009881.1 1130632 1130708 D tRNA-Pro 1130632..1130708 Rickettsia akari str. Hartford 5644686 A1C_t06947 tRNA A1C_t06947 NC_009881.1 1165028 1165104 R tRNA-Arg complement(1165028..1165104) Rickettsia akari str. Hartford 5645300 A1C_t06951 tRNA A1C_t06951 NC_009881.1 1218699 1218773 R tRNA-Thr complement(1218699..1218773) Rickettsia akari str. Hartford 5645556 A1C_r01 rRNA A1C_r01 NC_009881.1 288151 290928 D 23S ribosomal RNA 288151..290928 Rickettsia akari str. Hartford 5696491 A1C_r06953 rRNA A1C_r06953 NC_009881.1 291173 291290 D 5S ribosomal RNA 291173..291290 Rickettsia akari str. Hartford 5645257 A1C_r06955 rRNA A1C_r06955 NC_009881.1 864179 865686 R 16S ribosomal RNA complement(864179..865686) Rickettsia akari str. Hartford 5644742