-- dump date 20111121_014213 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 293613000001 SEQ_END SEQ_END NC_009879.1 1159772 1159772 DR NC_009879.1; contig end 1159772..1159772 Rickettsia canadensis str. McKiel YP_001491739.1 CDS A1E_00005 NC_009879.1 1 822 D COG1806 Uncharacterized protein conserved in bacteria; hypothetical protein 1..822 Rickettsia canadensis str. McKiel 5626507 YP_001491740.1 CDS A1E_00010 NC_009879.1 1065 1382 D COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 1065..1382 Rickettsia canadensis str. McKiel 5626202 YP_001491741.1 CDS A1E_00015 NC_009879.1 1375 2136 D COG1129 ABC-type sugar transport system, ATPase component; O-antigen export system ATP-binding protein RfbE 1375..2136 Rickettsia canadensis str. McKiel 5626203 YP_001491742.1 CDS A1E_00020 NC_009879.1 2295 3071 D hypothetical protein 2295..3071 Rickettsia canadensis str. McKiel 5626204 YP_001491743.1 CDS A1E_00025 NC_009879.1 3068 6214 D undetermined function; putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase 3068..6214 Rickettsia canadensis str. McKiel 5626205 YP_001491744.1 CDS A1E_00030 NC_009879.1 6333 7127 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(6333..7127) Rickettsia canadensis str. McKiel 5626206 YP_001491745.1 CDS fabZ NC_009879.1 7135 7569 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(7135..7569) Rickettsia canadensis str. McKiel 5626207 YP_001491746.1 CDS lpxD NC_009879.1 7570 8598 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(7570..8598) Rickettsia canadensis str. McKiel 5626513 YP_001491747.1 CDS A1E_00045 NC_009879.1 8865 9845 D COG0042 tRNA-dihydrouridine synthase; nifR3-like protein 8865..9845 Rickettsia canadensis str. McKiel 5626515 YP_001491748.1 CDS A1E_00050 NC_009879.1 10469 10900 R COG0802 Predicted ATPase or kinase; hypothetical protein complement(10469..10900) Rickettsia canadensis str. McKiel 5626516 YP_001491749.1 CDS A1E_00055 NC_009879.1 10891 11694 R COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; zinc/manganese ABC transporter substrate binding protein complement(10891..11694) Rickettsia canadensis str. McKiel 5626517 YP_001491750.1 CDS A1E_00060 NC_009879.1 11798 13009 R COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; poly(A) polymerase complement(11798..13009) Rickettsia canadensis str. McKiel 5626518 YP_001491751.1 CDS A1E_00065 NC_009879.1 13738 14010 R ComEC/Rec2-related protein complement(13738..14010) Rickettsia canadensis str. McKiel 5625864 YP_001491752.1 CDS A1E_00070 NC_009879.1 14292 14453 D hypothetical protein 14292..14453 Rickettsia canadensis str. McKiel 5625865 YP_001491753.1 CDS A1E_00075 NC_009879.1 14710 19161 D cell surface antigen Sca1 14710..19161 Rickettsia canadensis str. McKiel 5625866 YP_001491754.1 CDS lpxD NC_009879.1 19742 20143 D COG0658 Predicted membrane metal-binding protein; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 19742..20143 Rickettsia canadensis str. McKiel 5625868 YP_001491755.1 CDS A1E_00085 NC_009879.1 21912 22403 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(21912..22403) Rickettsia canadensis str. McKiel 5626412 YP_001491756.1 CDS A1E_00090 NC_009879.1 22403 22870 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' complement(22403..22870) Rickettsia canadensis str. McKiel 5626413 YP_001491757.1 CDS A1E_00095 NC_009879.1 22888 23112 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(22888..23112) Rickettsia canadensis str. McKiel 5626414 YP_001491758.1 CDS A1E_00100 NC_009879.1 23287 24015 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(23287..24015) Rickettsia canadensis str. McKiel 5626415 YP_001491759.1 CDS A1E_00105 NC_009879.1 24020 24283 R COG5336 Uncharacterized protein conserved in bacteria; hypothetical protein complement(24020..24283) Rickettsia canadensis str. McKiel 5626416 YP_001491760.1 CDS A1E_00110 NC_009879.1 24453 25277 R COG1651 Protein-disulfide isomerase; protein-disulfide isomerase complement(24453..25277) Rickettsia canadensis str. McKiel 5626003 YP_001491761.1 CDS A1E_00115 NC_009879.1 25444 25971 D COG1329 Transcriptional regulators, similar to M. xanthus CarD; hypothetical protein 25444..25971 Rickettsia canadensis str. McKiel 5626004 YP_001491762.1 CDS A1E_00120 NC_009879.1 26180 27784 R COG0500 SAM-dependent methyltransferases; F0F1 ATP synthase subunit A complement(26180..27784) Rickettsia canadensis str. McKiel 5626005 YP_001491763.1 CDS recF NC_009879.1 27939 29021 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(27939..29021) Rickettsia canadensis str. McKiel 5626006 YP_001491764.1 CDS recF NC_009879.1 29046 29714 R recombination protein F complement(29046..29714) Rickettsia canadensis str. McKiel 5626007 YP_001491765.1 CDS A1E_00135 NC_009879.1 29838 29927 R COG1195 Recombinational DNA repair ATPase (RecF pathway); hypothetical protein complement(29838..29927) Rickettsia canadensis str. McKiel 5626208 YP_001491766.1 CDS A1E_00140 NC_009879.1 31347 31916 R COG1678 Putative transcriptional regulator; hypothetical protein complement(31347..31916) Rickettsia canadensis str. McKiel 5626209 YP_001491767.1 CDS A1E_00145 NC_009879.1 31988 32626 D hypothetical protein 31988..32626 Rickettsia canadensis str. McKiel 5626210 YP_001491768.1 CDS A1E_00150 NC_009879.1 33032 33145 D hypothetical protein 33032..33145 Rickettsia canadensis str. McKiel 5626211 YP_001491769.1 CDS A1E_00155 NC_009879.1 33425 34747 R hypothetical protein complement(33425..34747) Rickettsia canadensis str. McKiel 5626212 YP_001491770.1 CDS A1E_00160 NC_009879.1 34766 34900 R COG1286 Uncharacterized membrane protein, required for colicin V production; hypothetical protein complement(34766..34900) Rickettsia canadensis str. McKiel 5626743 YP_001491771.1 CDS A1E_00165 NC_009879.1 36670 39246 D clpB protein 36670..39246 Rickettsia canadensis str. McKiel 5626744 YP_001491772.1 CDS A1E_00170 NC_009879.1 39386 39874 R COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein complement(39386..39874) Rickettsia canadensis str. McKiel 5626745 YP_001491773.1 CDS A1E_00175 NC_009879.1 40067 41095 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(40067..41095) Rickettsia canadensis str. McKiel 5626746 YP_001491774.1 CDS A1E_00180 NC_009879.1 41107 42300 R COG1398 Fatty-acid desaturase; O-sialoglycoprotein endopeptidase complement(41107..42300) Rickettsia canadensis str. McKiel 5626747 YP_001491775.1 CDS rpsF NC_009879.1 43248 43613 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 43248..43613 Rickettsia canadensis str. McKiel 5625945 YP_001491776.1 CDS rpsR NC_009879.1 43638 43925 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 43638..43925 Rickettsia canadensis str. McKiel 5625946 YP_001491777.1 CDS rplI NC_009879.1 43937 44452 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 43937..44452 Rickettsia canadensis str. McKiel 5625947 YP_001491778.1 CDS A1E_00200 NC_009879.1 44961 46259 D COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile)-lysidine synthetase TilS 44961..46259 Rickettsia canadensis str. McKiel 5625948 YP_001491779.1 CDS rplI NC_009879.1 46356 48266 D COG0465 ATP-dependent Zn proteases; 50S ribosomal protein L9 46356..48266 Rickettsia canadensis str. McKiel 5625949 YP_001491780.1 CDS sdhB NC_009879.1 48267 49052 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 48267..49052 Rickettsia canadensis str. McKiel 5626180 YP_001491781.1 CDS sdhB NC_009879.1 50050 51126 R COG1565 Uncharacterized conserved protein; succinate dehydrogenase iron-sulfur subunit complement(50050..51126) Rickettsia canadensis str. McKiel 5626181 YP_001491782.1 CDS A1E_00220 NC_009879.1 51105 51884 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(51105..51884) Rickettsia canadensis str. McKiel 5626182 YP_001491783.1 CDS A1E_00225 NC_009879.1 52158 53309 D COG0668 Small-conductance mechanosensitive channel; putative carbamate kinase 52158..53309 Rickettsia canadensis str. McKiel 5626183 YP_001491784.1 CDS A1E_00230 NC_009879.1 53499 55181 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 53499..55181 Rickettsia canadensis str. McKiel 5626184 YP_001491785.1 CDS A1E_00235 NC_009879.1 55181 55726 D CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 55181..55726 Rickettsia canadensis str. McKiel 5626354 YP_001491786.1 CDS A1E_00240 NC_009879.1 56122 56274 D hypothetical protein 56122..56274 Rickettsia canadensis str. McKiel 5626355 YP_001491787.1 CDS A1E_00245 NC_009879.1 56527 56925 R COG0558 Phosphatidylglycerophosphate synthase; hypothetical protein complement(56527..56925) Rickettsia canadensis str. McKiel 5626356 YP_001491788.1 CDS A1E_00250 NC_009879.1 58011 59516 D COG3202 ATP/ADP translocase; ADP,ATP carrier protein 58011..59516 Rickettsia canadensis str. McKiel 5626357 YP_001491789.1 CDS A1E_00255 NC_009879.1 59583 60872 D COG2271 Sugar phosphate permease; putative inner membrane protein translocase component YidC 59583..60872 Rickettsia canadensis str. McKiel 5626358 YP_001491790.1 CDS ndk NC_009879.1 60902 61324 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 60902..61324 Rickettsia canadensis str. McKiel 5626094 YP_001491791.1 CDS A1E_00265 NC_009879.1 61328 63202 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 61328..63202 Rickettsia canadensis str. McKiel 5626095 YP_001491792.1 CDS A1E_00270 NC_009879.1 63722 64489 D COG1192 ATPases involved in chromosome partitioning; soj protein 63722..64489 Rickettsia canadensis str. McKiel 5626096 YP_001491793.1 CDS A1E_00275 NC_009879.1 64476 65336 D COG1475 Predicted transcriptional regulators; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 64476..65336 Rickettsia canadensis str. McKiel 5626097 YP_001491794.1 CDS A1E_00280 NC_009879.1 65627 67294 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 65627..67294 Rickettsia canadensis str. McKiel 5626098 YP_001491795.1 CDS A1E_00285 NC_009879.1 67297 67614 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; putative ABC transporter ATP-binding component 67297..67614 Rickettsia canadensis str. McKiel 5626872 YP_001491796.1 CDS A1E_00290 NC_009879.1 67649 68473 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 67649..68473 Rickettsia canadensis str. McKiel 5626873 YP_001491797.1 CDS A1E_00295 NC_009879.1 69000 69086 D COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; hypothetical protein 69000..69086 Rickettsia canadensis str. McKiel 5626874 YP_001491798.1 CDS A1E_00300 NC_009879.1 69865 70197 R COG0316 Uncharacterized conserved protein; 2-dehydro-3-deoxyphosphooctonate aldolase complement(69865..70197) Rickettsia canadensis str. McKiel 5626875 YP_001491799.1 CDS A1E_00305 NC_009879.1 70360 71490 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 70360..71490 Rickettsia canadensis str. McKiel 5626876 YP_001491800.1 CDS argS NC_009879.1 71666 73396 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 71666..73396 Rickettsia canadensis str. McKiel 5625853 YP_001491801.1 CDS argS NC_009879.1 73472 74143 D COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase 73472..74143 Rickettsia canadensis str. McKiel 5625854 YP_001491802.1 CDS A1E_00320 NC_009879.1 74328 76544 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 74328..76544 Rickettsia canadensis str. McKiel 5625855 YP_001491803.1 CDS A1E_00325 NC_009879.1 76908 78230 R COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA topoisomerase IV subunit A complement(76908..78230) Rickettsia canadensis str. McKiel 5625856 YP_001491804.1 CDS dcd NC_009879.1 78514 79080 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 78514..79080 Rickettsia canadensis str. McKiel 5625857 YP_001491805.1 CDS A1E_00335 NC_009879.1 79177 79635 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 79177..79635 Rickettsia canadensis str. McKiel 5626707 YP_001491806.1 CDS A1E_00340 NC_009879.1 79861 80574 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; preprotein translocase subunit SecB 79861..80574 Rickettsia canadensis str. McKiel 5626708 YP_001491807.1 CDS queF NC_009879.1 80578 81399 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 80578..81399 Rickettsia canadensis str. McKiel 5626709 YP_001491808.1 CDS A1E_00350 NC_009879.1 81672 82232 R COG3820 Uncharacterized protein conserved in bacteria; hypothetical protein complement(81672..82232) Rickettsia canadensis str. McKiel 5626710 YP_001491809.1 CDS A1E_00360 NC_009879.1 82887 82976 R hypothetical protein complement(82887..82976) Rickettsia canadensis str. McKiel 5626711 YP_001491810.1 CDS A1E_00370 NC_009879.1 83232 83489 D COG1282 NAD/NADP transhydrogenase beta subunit; hypothetical protein 83232..83489 Rickettsia canadensis str. McKiel 5626052 YP_001491811.1 CDS A1E_00380 NC_009879.1 83991 84722 R COG3047 Outer membrane protein W; hypothetical protein complement(83991..84722) Rickettsia canadensis str. McKiel 5626053 YP_001491812.1 CDS A1E_00385 NC_009879.1 84866 85750 D COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; S-adenosylmethionine transporter 84866..85750 Rickettsia canadensis str. McKiel 5626054 YP_001491813.1 CDS queF NC_009879.1 85737 86999 D 7-cyano-7-deazaguanine reductase 85737..86999 Rickettsia canadensis str. McKiel 5626055 YP_001491814.1 CDS secG NC_009879.1 87321 87623 D COG0477 Permeases of the major facilitator superfamily; preprotein translocase subunit SecG 87321..87623 Rickettsia canadensis str. McKiel 5626712 YP_001491815.1 CDS A1E_00400 NC_009879.1 87913 88575 D hypothetical protein 87913..88575 Rickettsia canadensis str. McKiel 5626713 YP_001491816.1 CDS secG NC_009879.1 88817 94246 R COG1738 Uncharacterized conserved protein; preprotein translocase subunit SecG complement(88817..94246) Rickettsia canadensis str. McKiel 5626714 YP_001491817.1 CDS cysS NC_009879.1 94415 95794 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 94415..95794 Rickettsia canadensis str. McKiel 5626715 YP_001491818.1 CDS rpsB NC_009879.1 96094 96981 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 96094..96981 Rickettsia canadensis str. McKiel 5625831 YP_001491819.1 CDS tsf NC_009879.1 97003 97932 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 97003..97932 Rickettsia canadensis str. McKiel 5625832 YP_001491820.1 CDS A1E_00425 NC_009879.1 98936 100189 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(98936..100189) Rickettsia canadensis str. McKiel 5625833 YP_001491821.1 CDS A1E_00430 NC_009879.1 100186 100842 R COG2121 Uncharacterized protein conserved in bacteria; 3-deoxy-D-manno-octulosonic-acid transferase complement(100186..100842) Rickettsia canadensis str. McKiel 5625834 YP_001491822.1 CDS A1E_00435 NC_009879.1 100917 102137 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(100917..102137) Rickettsia canadensis str. McKiel 5625835 YP_001491823.1 CDS A1E_00440 NC_009879.1 102411 103418 D COG0457 FOG: TPR repeat; hypothetical protein 102411..103418 Rickettsia canadensis str. McKiel 5626508 YP_001491824.1 CDS A1E_00445 NC_009879.1 103393 104178 D COG2853 Surface lipoprotein; vacJ lipoprotein precursor 103393..104178 Rickettsia canadensis str. McKiel 5626509 YP_001491825.1 CDS A1E_00450 NC_009879.1 104204 104794 D COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component; aspartate aminotransferase 104204..104794 Rickettsia canadensis str. McKiel 5626510 YP_001491826.1 CDS alr NC_009879.1 105806 106873 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 105806..106873 Rickettsia canadensis str. McKiel 5626511 YP_001491827.1 CDS A1E_00460 NC_009879.1 107108 107887 D COG0767 ABC-type transport system involved in resistance to organic solvents, permease component; ABC transporter permease protein 107108..107887 Rickettsia canadensis str. McKiel 5626512 YP_001491828.1 CDS A1E_00465 NC_009879.1 107890 108651 D ribonucleotide ABC transporter ATP-binding protein 107890..108651 Rickettsia canadensis str. McKiel 5626275 YP_001491829.1 CDS alr NC_009879.1 108694 108942 D COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component; alanine racemase 108694..108942 Rickettsia canadensis str. McKiel 5626276 YP_001491830.1 CDS rpmB NC_009879.1 109015 109308 D required for 70S ribosome assembly; 50S ribosomal protein L28 109015..109308 Rickettsia canadensis str. McKiel 5626277 YP_001491831.1 CDS A1E_00480 NC_009879.1 109305 109541 D RpmE; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 109305..109541 Rickettsia canadensis str. McKiel 5626278 YP_001491832.1 CDS engB NC_009879.1 110321 110980 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 110321..110980 Rickettsia canadensis str. McKiel 5626628 YP_001491833.1 CDS A1E_00490 NC_009879.1 111131 111256 D COG0218 Predicted GTPase; acetylglutamate kinase 111131..111256 Rickettsia canadensis str. McKiel 5626629 YP_001491834.1 CDS A1E_00495 NC_009879.1 111737 112024 D COG3702 Type IV secretory pathway, VirB3 components; type IV secretion system protein VirB3 111737..112024 Rickettsia canadensis str. McKiel 5626630 YP_001491835.1 CDS A1E_00500 NC_009879.1 112279 114696 D COG3451 Type IV secretory pathway, VirB4 components; type IV secretion system ATPase VirB4 112279..114696 Rickettsia canadensis str. McKiel 5626631 YP_001491836.1 CDS A1E_00505 NC_009879.1 114838 118152 D COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 114838..118152 Rickettsia canadensis str. McKiel 5626035 YP_001491837.1 CDS A1E_00510 NC_009879.1 118139 120157 D COG3704 Type IV secretory pathway, VirB6 components; TrbL/VirB6 plasmid conjugative transfer protein 118139..120157 Rickettsia canadensis str. McKiel 5626036 YP_001491838.1 CDS A1E_00515 NC_009879.1 120164 123070 D COG3704 Type IV secretory pathway, VirB6 components; VirB6-like protein of the type IV secretion system 120164..123070 Rickettsia canadensis str. McKiel 5626037 YP_001491839.1 CDS A1E_00520 NC_009879.1 123077 125743 D COG3704 Type IV secretory pathway, VirB6 components; hypothetical protein 123077..125743 Rickettsia canadensis str. McKiel 5626038 YP_001491840.1 CDS A1E_00525 NC_009879.1 125852 129292 D hypothetical protein 125852..129292 Rickettsia canadensis str. McKiel 5626039 YP_001491841.1 CDS A1E_00540 NC_009879.1 130793 130897 D GTPase EngB 130793..130897 Rickettsia canadensis str. McKiel 5626696 YP_001491842.1 CDS A1E_00545 NC_009879.1 130964 131041 D hypothetical protein 130964..131041 Rickettsia canadensis str. McKiel 5626697 YP_001491843.1 CDS A1E_00550 NC_009879.1 132049 132165 D hypothetical protein 132049..132165 Rickettsia canadensis str. McKiel 5626698 YP_001491844.1 CDS A1E_00555 NC_009879.1 132389 132664 D COG0280 Phosphotransacetylase; hypothetical protein 132389..132664 Rickettsia canadensis str. McKiel 5626699 YP_001491845.1 CDS trmD NC_009879.1 132753 133415 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 132753..133415 Rickettsia canadensis str. McKiel 5626700 YP_001491846.1 CDS rplS NC_009879.1 133672 134088 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 133672..134088 Rickettsia canadensis str. McKiel 5626390 YP_001491847.1 CDS rplS NC_009879.1 134364 134600 R COG3750 Uncharacterized protein conserved in bacteria; hypothetical protein complement(134364..134600) Rickettsia canadensis str. McKiel 5626391 YP_001491848.1 CDS secF NC_009879.1 134672 135604 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 134672..135604 Rickettsia canadensis str. McKiel 5626392 YP_001491849.1 CDS A1E_00580 NC_009879.1 135718 136980 D part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 135718..136980 Rickettsia canadensis str. McKiel 5626393 YP_001491850.1 CDS secF NC_009879.1 137144 137941 D COG0681 Signal peptidase I; preprotein translocase subunit SecF 137144..137941 Rickettsia canadensis str. McKiel 5626394 YP_001491851.1 CDS rnc NC_009879.1 137941 138624 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 137941..138624 Rickettsia canadensis str. McKiel 5625998 YP_001491852.1 CDS era NC_009879.1 138617 139504 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 138617..139504 Rickettsia canadensis str. McKiel 5625999 YP_001491853.1 CDS ruvC NC_009879.1 139628 140170 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 139628..140170 Rickettsia canadensis str. McKiel 5626000 YP_001491854.1 CDS A1E_00605 NC_009879.1 140172 140864 D COG0565 rRNA methylase; tRNA/rRNA methyltransferase 140172..140864 Rickettsia canadensis str. McKiel 5626001 YP_001491855.1 CDS A1E_00610 NC_009879.1 141014 142102 R COG3660 Predicted nucleoside-diphosphate-sugar epimerase; hypothetical protein complement(141014..142102) Rickettsia canadensis str. McKiel 5626002 YP_001491856.1 CDS A1E_00615 NC_009879.1 142099 143205 R COG0489 ATPases involved in chromosome partitioning; Mrp protein complement(142099..143205) Rickettsia canadensis str. McKiel 5625809 YP_001491857.1 CDS A1E_00620 NC_009879.1 143306 144346 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; protease activity modulator HflK 143306..144346 Rickettsia canadensis str. McKiel 5625810 YP_001491858.1 CDS A1E_00625 NC_009879.1 144517 145377 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hflc protein (hflc) 144517..145377 Rickettsia canadensis str. McKiel 5625811 YP_001491859.1 CDS ruvC NC_009879.1 145398 146933 D COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Holliday junction resolvase 145398..146933 Rickettsia canadensis str. McKiel 5625812 YP_001491860.1 CDS A1E_00635 NC_009879.1 147028 147777 D COG1054 Predicted sulfurtransferase; hypothetical protein 147028..147777 Rickettsia canadensis str. McKiel 5625813 YP_001491861.1 CDS A1E_00640 NC_009879.1 147799 148173 D succinate dehydrogenase cytochrome b-556 subunit 147799..148173 Rickettsia canadensis str. McKiel 5626197 YP_001491862.1 CDS A1E_00645 NC_009879.1 148506 148625 D COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; hypothetical protein 148506..148625 Rickettsia canadensis str. McKiel 5626198 YP_001491863.1 CDS A1E_00650 NC_009879.1 149004 149381 D COG2142 Succinate dehydrogenase, hydrophobic anchor subunit; hypothetical protein 149004..149381 Rickettsia canadensis str. McKiel 5626199 YP_001491864.1 CDS sdhA NC_009879.1 149579 151369 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 149579..151369 Rickettsia canadensis str. McKiel 5626200 YP_001491865.1 CDS A1E_00660 NC_009879.1 151411 151509 R COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; hypothetical protein complement(151411..151509) Rickettsia canadensis str. McKiel 5626201 YP_001491866.1 CDS sdhA NC_009879.1 151578 152234 D COG0765 ABC-type amino acid transport system, permease component; succinate dehydrogenase flavoprotein subunit 151578..152234 Rickettsia canadensis str. McKiel 5626291 YP_001491867.1 CDS rpsL NC_009879.1 152392 152781 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 152392..152781 Rickettsia canadensis str. McKiel 5626292 YP_001491868.1 CDS A1E_00675 NC_009879.1 152809 153291 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 152809..153291 Rickettsia canadensis str. McKiel 5626293 YP_001491869.1 CDS A1E_00680 NC_009879.1 153304 155376 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 153304..155376 Rickettsia canadensis str. McKiel 5626294 YP_001491870.1 CDS secE NC_009879.1 155746 156009 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 155746..156009 Rickettsia canadensis str. McKiel 5626381 YP_001491871.1 CDS nusG NC_009879.1 156025 156603 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 156025..156603 Rickettsia canadensis str. McKiel 5626382 YP_001491872.1 CDS rplK NC_009879.1 156835 157272 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 156835..157272 Rickettsia canadensis str. McKiel 5626383 YP_001491873.1 CDS rplA NC_009879.1 157278 157997 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 157278..157997 Rickettsia canadensis str. McKiel 5626384 YP_001491874.1 CDS rplJ NC_009879.1 158282 158791 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 158282..158791 Rickettsia canadensis str. McKiel 5626567 YP_001491875.1 CDS rplL NC_009879.1 158823 159200 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 158823..159200 Rickettsia canadensis str. McKiel 5626568 YP_001491876.1 CDS rpoB NC_009879.1 159903 164024 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 159903..164024 Rickettsia canadensis str. McKiel 5626569 YP_001491877.1 CDS A1E_00720 NC_009879.1 164217 168353 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 164217..168353 Rickettsia canadensis str. McKiel 5626570 YP_001491878.1 CDS A1E_00725 NC_009879.1 168570 169487 R COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' complement(168570..169487) Rickettsia canadensis str. McKiel 5626571 YP_001491879.1 CDS A1E_00730 NC_009879.1 169864 171366 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 169864..171366 Rickettsia canadensis str. McKiel 5626691 YP_001491880.1 CDS A1E_00735 NC_009879.1 171560 172354 D hypothetical protein 171560..172354 Rickettsia canadensis str. McKiel 5626692 YP_001491881.1 CDS A1E_00740 NC_009879.1 172435 172866 D COG1192 ATPases involved in chromosome partitioning; leucyl aminopeptidase 172435..172866 Rickettsia canadensis str. McKiel 5626693 YP_001491882.1 CDS aspS NC_009879.1 172942 174750 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 172942..174750 Rickettsia canadensis str. McKiel 5626694 YP_001491883.1 CDS aspS NC_009879.1 175182 175892 R COG0670 Integral membrane protein, interacts with FtsH; aspartyl-tRNA synthetase complement(175182..175892) Rickettsia canadensis str. McKiel 5626695 YP_001491884.1 CDS A1E_00755 NC_009879.1 175958 176680 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(175958..176680) Rickettsia canadensis str. McKiel 5625826 YP_001491885.1 CDS A1E_00760 NC_009879.1 176688 177170 R COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein complement(176688..177170) Rickettsia canadensis str. McKiel 5625827 YP_001491886.1 CDS A1E_00765 NC_009879.1 177155 177880 R dihydrodipicolinate reductase complement(177155..177880) Rickettsia canadensis str. McKiel 5625828 YP_001491887.1 CDS A1E_00770 NC_009879.1 177877 177960 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; hypothetical protein complement(177877..177960) Rickettsia canadensis str. McKiel 5625829 YP_001491888.1 CDS gatB NC_009879.1 177960 179411 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(177960..179411) Rickettsia canadensis str. McKiel 5625830 YP_001491889.1 CDS gatA NC_009879.1 179414 180895 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(179414..180895) Rickettsia canadensis str. McKiel 5626492 YP_001491890.1 CDS gatC NC_009879.1 180898 181200 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(180898..181200) Rickettsia canadensis str. McKiel 5626493 YP_001491891.1 CDS frr NC_009879.1 181370 181930 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(181370..181930) Rickettsia canadensis str. McKiel 5626494 YP_001491892.1 CDS pyrH NC_009879.1 181934 182662 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(181934..182662) Rickettsia canadensis str. McKiel 5626495 YP_001491893.1 CDS A1E_00800 NC_009879.1 182659 182991 R subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E complement(182659..182991) Rickettsia canadensis str. McKiel 5626496 YP_001491894.1 CDS A1E_00805 NC_009879.1 182975 184537 R COG0477 Permeases of the major facilitator superfamily; multidrug resistance protein B complement(182975..184537) Rickettsia canadensis str. McKiel 5626766 YP_001491895.1 CDS A1E_00810 NC_009879.1 184863 185066 D COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; hypothetical protein 184863..185066 Rickettsia canadensis str. McKiel 5626767 YP_001491896.1 CDS A1E_00815 NC_009879.1 185970 188276 R COG4775 Outer membrane protein/protective antigen OMA87; Outer membrane protein omp1 complement(185970..188276) Rickettsia canadensis str. McKiel 5626769 YP_001491897.1 CDS A1E_00820 NC_009879.1 188580 189656 R COG0750 Predicted membrane-associated Zn-dependent proteases 1; putative monovalent cation/H+ antiporter subunit E complement(188580..189656) Rickettsia canadensis str. McKiel 5626900 YP_001491898.1 CDS nusB NC_009879.1 189855 190391 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 189855..190391 Rickettsia canadensis str. McKiel 5626901 YP_001491899.1 CDS A1E_00830 NC_009879.1 190388 191071 D ribosomal RNA large subunit methyltransferase J 190388..191071 Rickettsia canadensis str. McKiel 5626902 YP_001491900.1 CDS A1E_00835 NC_009879.1 191118 191339 R hypothetical protein complement(191118..191339) Rickettsia canadensis str. McKiel 5626903 YP_001491901.1 CDS A1E_00840 NC_009879.1 191333 192448 R COG0293 23S rRNA methylase; hypothetical protein complement(191333..192448) Rickettsia canadensis str. McKiel 5626904 YP_001491902.1 CDS nusB NC_009879.1 193122 193562 R COG2867 Oligoketide cyclase/lipid transport protein; transcription antitermination protein NusB complement(193122..193562) Rickettsia canadensis str. McKiel 5626618 YP_001491903.1 CDS dapD NC_009879.1 194099 194923 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(194099..194923) Rickettsia canadensis str. McKiel 5626619 YP_001491904.1 CDS A1E_00855 NC_009879.1 195003 195623 D hypothetical protein 195003..195623 Rickettsia canadensis str. McKiel 5626620 YP_001491905.1 CDS A1E_00860 NC_009879.1 195946 196302 R COG2171 Tetrahydrodipicolinate N-succinyltransferase; hypothetical protein complement(195946..196302) Rickettsia canadensis str. McKiel 5626621 YP_001491906.1 CDS A1E_00865 NC_009879.1 196452 197303 R COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; cytochrome c oxidase subunit III complement(196452..197303) Rickettsia canadensis str. McKiel 5626622 YP_001491907.1 CDS dapD NC_009879.1 197901 198440 R COG2941 Ubiquinone biosynthesis protein COQ7; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase complement(197901..198440) Rickettsia canadensis str. McKiel 5626727 YP_001491908.1 CDS holA NC_009879.1 198589 199560 R required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(198589..199560) Rickettsia canadensis str. McKiel 5626728 YP_001491909.1 CDS A1E_00880 NC_009879.1 199727 200197 R hypothetical protein complement(199727..200197) Rickettsia canadensis str. McKiel 5626729 YP_001491910.1 CDS A1E_00885 NC_009879.1 200419 200691 D hypothetical protein 200419..200691 Rickettsia canadensis str. McKiel 5626730 YP_001491911.1 CDS A1E_00890 NC_009879.1 200877 200969 R COG1466 DNA polymerase III, delta subunit; hypothetical protein complement(200877..200969) Rickettsia canadensis str. McKiel 5626731 YP_001491912.1 CDS holA NC_009879.1 201646 203139 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; DNA polymerase III subunit delta complement(201646..203139) Rickettsia canadensis str. McKiel 5626433 YP_001491913.1 CDS dnaK NC_009879.1 203206 205089 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 203206..205089 Rickettsia canadensis str. McKiel 5626434 YP_001491914.1 CDS A1E_00905 NC_009879.1 205199 206326 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 205199..206326 Rickettsia canadensis str. McKiel 5626435 YP_001491915.1 CDS A1E_00910 NC_009879.1 206461 206649 D COG4572 Putative cation transport regulator; hypothetical protein 206461..206649 Rickettsia canadensis str. McKiel 5626436 YP_001491916.1 CDS A1E_00915 NC_009879.1 206730 207473 D COG4105 DNA uptake lipoprotein; hypothetical protein 206730..207473 Rickettsia canadensis str. McKiel 5626437 YP_001491917.1 CDS A1E_00920 NC_009879.1 207631 209271 D COG0497 ATPase involved in DNA repair; DNA repair protein RecN 207631..209271 Rickettsia canadensis str. McKiel 5626364 YP_001491918.1 CDS dnaK NC_009879.1 209552 210946 D COG2317 Zn-dependent carboxypeptidase; molecular chaperone DnaK 209552..210946 Rickettsia canadensis str. McKiel 5626365 YP_001491919.1 CDS sucA NC_009879.1 211183 213972 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 211183..213972 Rickettsia canadensis str. McKiel 5626366 YP_001491920.1 CDS A1E_00935 NC_009879.1 214141 215346 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 214141..215346 Rickettsia canadensis str. McKiel 5626367 YP_001491921.1 CDS A1E_00940 NC_009879.1 215505 215921 D COG0720 6-pyruvoyl-tetrahydropterin synthase; hypothetical protein 215505..215921 Rickettsia canadensis str. McKiel 5626368 YP_001491922.1 CDS A1E_00945 NC_009879.1 215924 216388 D COG1324 Uncharacterized protein involved in tolerance to divalent cations; periplasmic divalent cation tolerance protein 215924..216388 Rickettsia canadensis str. McKiel 5626648 YP_001491923.1 CDS A1E_00950 NC_009879.1 216429 217628 D proton/sodium-glutamate symport protein 216429..217628 Rickettsia canadensis str. McKiel 5626649 YP_001491924.1 CDS A1E_00955 NC_009879.1 217966 218178 D dihydrolipoamide acetyltransferase 217966..218178 Rickettsia canadensis str. McKiel 5626650 YP_001491925.1 CDS A1E_00960 NC_009879.1 219739 219831 R COG1301 Na+/H+-dicarboxylate symporters; hypothetical protein complement(219739..219831) Rickettsia canadensis str. McKiel 5626651 YP_001491926.1 CDS A1E_00965 NC_009879.1 220076 221236 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(220076..221236) Rickettsia canadensis str. McKiel 5626652 YP_001491927.1 CDS A1E_00970 NC_009879.1 221532 221672 R COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; transposase complement(221532..221672) Rickettsia canadensis str. McKiel 5626643 YP_001491928.1 CDS A1E_00975 NC_009879.1 222056 223405 R COG0541 Signal recognition particle GTPase; coproporphyrinogen III oxidase complement(222056..223405) Rickettsia canadensis str. McKiel 5626644 YP_001491929.1 CDS A1E_00980 NC_009879.1 223601 224395 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(223601..224395) Rickettsia canadensis str. McKiel 5626645 YP_001491930.1 CDS A1E_00985 NC_009879.1 224693 225025 R COG0776 Bacterial nucleoid DNA-binding protein; DNA-binding protein HU complement(224693..225025) Rickettsia canadensis str. McKiel 5626646 YP_001491931.1 CDS A1E_00990 NC_009879.1 225535 228561 D COG0841 Cation/multidrug efflux pump; hydrophobe/amphiphile efflux-1 HAE1 family protein 225535..228561 Rickettsia canadensis str. McKiel 5626647 YP_001491932.1 CDS A1E_00995 NC_009879.1 228648 228857 D COG2155 Uncharacterized conserved protein; hypothetical protein 228648..228857 Rickettsia canadensis str. McKiel 5626438 YP_001491933.1 CDS A1E_01000 NC_009879.1 228970 229743 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(228970..229743) Rickettsia canadensis str. McKiel 5626439 YP_001491934.1 CDS A1E_01005 NC_009879.1 230225 230386 R hypothetical protein complement(230225..230386) Rickettsia canadensis str. McKiel 5626440 YP_001491935.1 CDS A1E_01010 NC_009879.1 230518 230709 R bifunctional penicillin-binding protein 1C complement(230518..230709) Rickettsia canadensis str. McKiel 5626441 YP_001491936.1 CDS A1E_01015 NC_009879.1 231923 232018 D COG1385 Uncharacterized protein conserved in bacteria; hypothetical protein 231923..232018 Rickettsia canadensis str. McKiel 5626442 YP_001491937.1 CDS A1E_01020 NC_009879.1 232940 233386 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; hypothetical protein complement(232940..233386) Rickettsia canadensis str. McKiel 5625892 YP_001491938.1 CDS A1E_01025 NC_009879.1 233396 234346 R hypothetical protein complement(233396..234346) Rickettsia canadensis str. McKiel 5625893 YP_001491939.1 CDS A1E_01030 NC_009879.1 234351 235421 R COG2358 TRAP-type uncharacterized transport system, periplasmic component; hypothetical protein complement(234351..235421) Rickettsia canadensis str. McKiel 5625894 YP_001491940.1 CDS A1E_01035 NC_009879.1 235434 235772 R COG0633 Ferredoxin; DNA polymerase III subunit delta' complement(235434..235772) Rickettsia canadensis str. McKiel 5625895 YP_001491941.1 CDS hscA NC_009879.1 235834 237771 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(235834..237771) Rickettsia canadensis str. McKiel 5625896 YP_001491942.1 CDS hscB NC_009879.1 237762 238262 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(237762..238262) Rickettsia canadensis str. McKiel 5626244 YP_001491943.1 CDS rnhB NC_009879.1 238535 239125 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 238535..239125 Rickettsia canadensis str. McKiel 5626245 YP_001491944.1 CDS A1E_01055 NC_009879.1 239262 241247 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(239262..241247) Rickettsia canadensis str. McKiel 5626246 YP_001491945.1 CDS A1E_01060 NC_009879.1 241318 241629 D COG0695 Glutaredoxin and related proteins; glutaredoxin, GrxC family protein 241318..241629 Rickettsia canadensis str. McKiel 5626247 YP_001491946.1 CDS A1E_01080 NC_009879.1 243888 243989 D hypothetical protein 243888..243989 Rickettsia canadensis str. McKiel 5626248 YP_001491947.1 CDS A1E_01085 NC_009879.1 244036 244212 D hypothetical protein 244036..244212 Rickettsia canadensis str. McKiel 5625836 YP_001491948.1 CDS A1E_01090 NC_009879.1 244206 244334 D COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components; hypothetical protein 244206..244334 Rickettsia canadensis str. McKiel 5625837 YP_001491949.1 CDS A1E_01095 NC_009879.1 245722 248340 R COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); ATP-dependent helicase complement(245722..248340) Rickettsia canadensis str. McKiel 5625838 YP_001491950.1 CDS A1E_01100 NC_009879.1 248521 249222 R COG3346 Uncharacterized conserved protein; excinuclease ABC subunit B complement(248521..249222) Rickettsia canadensis str. McKiel 5625839 YP_001491951.1 CDS A1E_01105 NC_009879.1 249422 250111 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(249422..250111) Rickettsia canadensis str. McKiel 5625840 YP_001491952.1 CDS coaE NC_009879.1 250099 250674 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(250099..250674) Rickettsia canadensis str. McKiel 5625955 YP_001491953.1 CDS A1E_01115 NC_009879.1 250668 251480 R COG3494 Uncharacterized protein conserved in bacteria; hypothetical protein complement(250668..251480) Rickettsia canadensis str. McKiel 5625956 YP_001491954.1 CDS coaE NC_009879.1 252225 252704 D COG3814 Uncharacterized protein conserved in bacteria; dephospho-CoA kinase 252225..252704 Rickettsia canadensis str. McKiel 5625957 YP_001491955.1 CDS rnhA NC_009879.1 252709 253176 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 252709..253176 Rickettsia canadensis str. McKiel 5625958 YP_001491956.1 CDS A1E_01130 NC_009879.1 253164 253607 D COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit; hypothetical protein 253164..253607 Rickettsia canadensis str. McKiel 5625959 YP_001491957.1 CDS A1E_01135 NC_009879.1 253629 254081 D ABC transporter substrate binding protein 253629..254081 Rickettsia canadensis str. McKiel 5625793 YP_001491958.1 CDS A1E_01140 NC_009879.1 254695 254877 R hypothetical protein complement(254695..254877) Rickettsia canadensis str. McKiel 5625794 YP_001491959.1 CDS A1E_01145 NC_009879.1 255361 255621 D hypothetical protein 255361..255621 Rickettsia canadensis str. McKiel 5625795 YP_001491961.1 CDS A1E_01155 NC_009879.1 257257 257397 R hypothetical protein complement(257257..257397) Rickettsia canadensis str. McKiel 5625797 YP_001491962.1 CDS A1E_01160 NC_009879.1 258853 259002 D hypothetical protein 258853..259002 Rickettsia canadensis str. McKiel 5626563 YP_001491963.1 CDS A1E_01165 NC_009879.1 259271 259483 R hypothetical protein complement(259271..259483) Rickettsia canadensis str. McKiel 5626565 YP_001491964.1 CDS A1E_01170 NC_009879.1 260074 260217 R COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component; hypothetical protein complement(260074..260217) Rickettsia canadensis str. McKiel 5626566 YP_001491965.1 CDS A1E_01175 NC_009879.1 260563 261450 R hypothetical protein complement(260563..261450) Rickettsia canadensis str. McKiel 5626169 YP_001491966.1 CDS A1E_01180 NC_009879.1 261693 261899 D COG0331 (acyl-carrier-protein) S-malonyltransferase; hypothetical protein 261693..261899 Rickettsia canadensis str. McKiel 5626170 YP_001491967.1 CDS A1E_01185 NC_009879.1 263214 265898 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 263214..265898 Rickettsia canadensis str. McKiel 5626171 YP_001491968.1 CDS A1E_01190 NC_009879.1 266245 266418 D hypothetical protein 266245..266418 Rickettsia canadensis str. McKiel 5626172 YP_001491969.1 CDS A1E_01195 NC_009879.1 266693 266797 R COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein complement(266693..266797) Rickettsia canadensis str. McKiel 5626173 YP_001491970.1 CDS def NC_009879.1 266962 267489 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 266962..267489 Rickettsia canadensis str. McKiel 5626146 YP_001491971.1 CDS fmt NC_009879.1 267486 268397 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 267486..268397 Rickettsia canadensis str. McKiel 5626147 YP_001491972.1 CDS A1E_01210 NC_009879.1 268733 268897 D COG0223 Methionyl-tRNA formyltransferase; hypothetical protein 268733..268897 Rickettsia canadensis str. McKiel 5626148 YP_001491973.1 CDS fmt NC_009879.1 273032 274213 R COG1485 Predicted ATPase; methionyl-tRNA formyltransferase complement(273032..274213) Rickettsia canadensis str. McKiel 5626150 YP_001491974.1 CDS A1E_01220 NC_009879.1 274733 275893 R COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(274733..275893) Rickettsia canadensis str. McKiel 5626359 YP_001491975.1 CDS A1E_01225 NC_009879.1 276529 278298 R multidrug ABC transporter ATP-binding protein complement(276529..278298) Rickettsia canadensis str. McKiel 5626360 YP_001491976.1 CDS A1E_01230 NC_009879.1 278483 278755 D COG1132 ABC-type multidrug transport system, ATPase and permease components; hypothetical protein 278483..278755 Rickettsia canadensis str. McKiel 5626361 YP_001491977.1 CDS A1E_01235 NC_009879.1 278927 280291 D COG1271 Cytochrome bd-type quinol oxidase, subunit 1; cytochrome d ubiquinol oxidase subunit I 278927..280291 Rickettsia canadensis str. McKiel 5626362 YP_001491978.1 CDS A1E_01240 NC_009879.1 280975 281994 D COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome d ubiquinol oxidase subunit II 280975..281994 Rickettsia canadensis str. McKiel 5626363 YP_001491979.1 CDS A1E_01245 NC_009879.1 282300 283106 D COG0463 Glycosyltransferases involved in cell wall biogenesis; Beta 1,4 glucosyltransferase 282300..283106 Rickettsia canadensis str. McKiel 5626664 YP_001491980.1 CDS A1E_01250 NC_009879.1 283084 284325 D COG0612 Predicted Zn-dependent peptidases; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 283084..284325 Rickettsia canadensis str. McKiel 5626665 YP_001491981.1 CDS A1E_01255 NC_009879.1 284335 285045 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 284335..285045 Rickettsia canadensis str. McKiel 5626666 YP_001491982.1 CDS A1E_01260 NC_009879.1 285235 286830 D COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 285235..286830 Rickettsia canadensis str. McKiel 5626667 YP_001491983.1 CDS thrS NC_009879.1 287042 288949 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 287042..288949 Rickettsia canadensis str. McKiel 5626668 YP_001491984.1 CDS A1E_01270 NC_009879.1 289923 290054 D hypothetical protein 289923..290054 Rickettsia canadensis str. McKiel 5626669 YP_001491985.1 CDS A1E_01275 NC_009879.1 290550 290768 R hypothetical protein complement(290550..290768) Rickettsia canadensis str. McKiel 5626481 YP_001491986.1 CDS A1E_01280 NC_009879.1 291489 291902 R hypothetical protein complement(291489..291902) Rickettsia canadensis str. McKiel 5626482 YP_001491987.1 CDS A1E_01285 NC_009879.1 292204 292371 R COG0441 Threonyl-tRNA synthetase; hypothetical protein complement(292204..292371) Rickettsia canadensis str. McKiel 5626483 YP_001491988.1 CDS A1E_01290 NC_009879.1 293262 293462 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 293262..293462 Rickettsia canadensis str. McKiel 5626484 YP_001491989.1 CDS A1E_01295 NC_009879.1 293377 293595 D COG1943 Transposase and inactivated derivatives; transposase IS200-family protein 293377..293595 Rickettsia canadensis str. McKiel 5626485 YP_001491990.1 CDS A1E_01300 NC_009879.1 293909 295273 D outer membrane protein tolC precursor 293909..295273 Rickettsia canadensis str. McKiel 5626675 YP_001491991.1 CDS A1E_01305 NC_009879.1 295305 295673 D COG1538 Outer membrane protein; hypothetical protein 295305..295673 Rickettsia canadensis str. McKiel 5626676 YP_001491992.1 CDS thrS NC_009879.1 295853 297634 D threonyl-tRNA synthetase 295853..297634 Rickettsia canadensis str. McKiel 5626677 YP_001491993.1 CDS A1E_01315 NC_009879.1 297801 299789 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 297801..299789 Rickettsia canadensis str. McKiel 5626678 YP_001491994.1 CDS A1E_01320 NC_009879.1 299958 301334 D COG0793 Periplasmic protease; tail-specific protease precursor 299958..301334 Rickettsia canadensis str. McKiel 5626679 YP_001491995.1 CDS A1E_01325 NC_009879.1 301577 303070 D COG0642 Signal transduction histidine kinase; histidine kinase sensor protein 301577..303070 Rickettsia canadensis str. McKiel 5626632 YP_001491996.1 CDS A1E_01330 NC_009879.1 303325 304065 D hypothetical protein 303325..304065 Rickettsia canadensis str. McKiel 5626633 YP_001491997.1 CDS A1E_01335 NC_009879.1 304078 304740 D COG1729 Uncharacterized protein conserved in bacteria; hypothetical protein 304078..304740 Rickettsia canadensis str. McKiel 5626634 YP_001491998.1 CDS A1E_01340 NC_009879.1 304763 306007 D COG1520 FOG: WD40-like repeat; DNA topoisomerase IV subunit B 304763..306007 Rickettsia canadensis str. McKiel 5626635 YP_001491999.1 CDS rplM NC_009879.1 306100 306576 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 306100..306576 Rickettsia canadensis str. McKiel 5626636 YP_001492000.1 CDS rpsI NC_009879.1 306573 307058 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 306573..307058 Rickettsia canadensis str. McKiel 5626327 YP_001492001.1 CDS A1E_01355 NC_009879.1 307503 307691 D COG2173 D-alanyl-D-alanine dipeptidase; D-alanyl-D-alanine dipeptidase 307503..307691 Rickettsia canadensis str. McKiel 5626329 YP_001492002.1 CDS rpsI NC_009879.1 308111 308440 D COG2154 Pterin-4a-carbinolamine dehydratase; 30S ribosomal protein S9 308111..308440 Rickettsia canadensis str. McKiel 5626330 YP_001492003.1 CDS A1E_01365 NC_009879.1 309068 309553 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(309068..309553) Rickettsia canadensis str. McKiel 5626732 YP_001492004.1 CDS pleD NC_009879.1 309578 310930 R involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD complement(309578..310930) Rickettsia canadensis str. McKiel 5626733 YP_001492005.1 CDS A1E_01375 NC_009879.1 311006 311572 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 311006..311572 Rickettsia canadensis str. McKiel 5626734 YP_001492006.1 CDS A1E_01380 NC_009879.1 311723 312466 D COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; extragenic suppressor protein SuhB 311723..312466 Rickettsia canadensis str. McKiel 5626735 YP_001492007.1 CDS A1E_01385 NC_009879.1 312532 312861 D COG0012 Predicted GTPase, probable translation factor; elongation factor P 312532..312861 Rickettsia canadensis str. McKiel 5626736 YP_001492008.1 CDS A1E_01390 NC_009879.1 312893 313588 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 312893..313588 Rickettsia canadensis str. McKiel 5626129 YP_001492009.1 CDS A1E_01395 NC_009879.1 313815 314588 D COG1183 Phosphatidylserine synthase; CDP-diacylglycerol--serine O-phosphatidyltransferase 313815..314588 Rickettsia canadensis str. McKiel 5626130 YP_001492010.1 CDS A1E_01400 NC_009879.1 314589 315641 D multidrug resistance protein A 314589..315641 Rickettsia canadensis str. McKiel 5626131 YP_001492011.1 CDS A1E_01405 NC_009879.1 316140 316343 R COG1566 Multidrug resistance efflux pump; hypothetical protein complement(316140..316343) Rickettsia canadensis str. McKiel 5626132 YP_001492012.1 CDS A1E_01410 NC_009879.1 316343 316585 R COG0271 Stress-induced morphogen (activity unknown); hypothetical protein complement(316343..316585) Rickettsia canadensis str. McKiel 5626133 YP_001492013.1 CDS A1E_01415 NC_009879.1 316647 317888 D COG2200 FOG: EAL domain; phosphatidylserine decarboxylase 316647..317888 Rickettsia canadensis str. McKiel 5626286 YP_001492014.1 CDS murC NC_009879.1 318046 319479 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 318046..319479 Rickettsia canadensis str. McKiel 5626287 YP_001492015.1 CDS murB NC_009879.1 319476 320369 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 319476..320369 Rickettsia canadensis str. McKiel 5626288 YP_001492016.1 CDS ddl NC_009879.1 320438 321502 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 320438..321502 Rickettsia canadensis str. McKiel 5626289 YP_001492017.1 CDS A1E_01435 NC_009879.1 321499 322302 D COG1589 Cell division septal protein; cell division protein ftsQ 321499..322302 Rickettsia canadensis str. McKiel 5626290 YP_001492018.1 CDS A1E_01440 NC_009879.1 322331 323566 D cell division protein FtsA 322331..323566 Rickettsia canadensis str. McKiel 5626078 YP_001492019.1 CDS A1E_01445 NC_009879.1 323713 323946 R hypothetical protein complement(323713..323946) Rickettsia canadensis str. McKiel 5626079 YP_001492020.1 CDS A1E_01450 NC_009879.1 325123 325590 R COG0849 Actin-like ATPase involved in cell division; hypothetical protein complement(325123..325590) Rickettsia canadensis str. McKiel 5626080 YP_001492021.1 CDS A1E_01455 NC_009879.1 325580 326101 R cytochrome c complement(325580..326101) Rickettsia canadensis str. McKiel 5626081 YP_001492022.1 CDS ddl NC_009879.1 326646 326819 D COG3474 Cytochrome c2; D-alanine--D-alanine ligase 326646..326819 Rickettsia canadensis str. McKiel 5626082 YP_001492023.1 CDS lpxC NC_009879.1 327248 328114 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(327248..328114) Rickettsia canadensis str. McKiel 5626217 YP_001492024.1 CDS A1E_01470 NC_009879.1 328307 329455 R COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; hypothetical protein complement(328307..329455) Rickettsia canadensis str. McKiel 5626218 YP_001492025.1 CDS A1E_01475 NC_009879.1 329882 331948 D COG1530 Ribonucleases G and E; ribonuclease E 329882..331948 Rickettsia canadensis str. McKiel 5626219 YP_001492026.1 CDS A1E_01480 NC_009879.1 332200 333171 D COG1612 Uncharacterized protein required for cytochrome oxidase assembly; cytochrome c oxidase assembly protein 332200..333171 Rickettsia canadensis str. McKiel 5626220 YP_001492027.1 CDS A1E_01485 NC_009879.1 333168 334079 D COG0564 Pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase C 333168..334079 Rickettsia canadensis str. McKiel 5626221 YP_001492028.1 CDS A1E_01490 NC_009879.1 334241 335422 D COG1680 Beta-lactamase class C and other penicillin binding proteins; penicillin-binding protein 4* 334241..335422 Rickettsia canadensis str. McKiel 5626073 YP_001492029.1 CDS A1E_01495 NC_009879.1 335423 336244 D COG0708 Exonuclease III; exodeoxyribonuclease III 335423..336244 Rickettsia canadensis str. McKiel 5626074 YP_001492030.1 CDS lpxC NC_009879.1 336312 337301 D COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 336312..337301 Rickettsia canadensis str. McKiel 5626075 YP_001492031.1 CDS A1E_01505 NC_009879.1 337430 338416 D catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 337430..338416 Rickettsia canadensis str. McKiel 5626076 YP_001492032.1 CDS A1E_01510 NC_009879.1 338639 340483 R GTP-binding protein complement(338639..340483) Rickettsia canadensis str. McKiel 5626077 YP_001492033.1 CDS A1E_01515 NC_009879.1 340784 340918 D hypothetical protein 340784..340918 Rickettsia canadensis str. McKiel 5626845 YP_001492034.1 CDS A1E_01520 NC_009879.1 340987 341250 D COG1217 Predicted membrane GTPase involved in stress response; hypothetical protein 340987..341250 Rickettsia canadensis str. McKiel 5626846 YP_001492035.1 CDS A1E_01525 NC_009879.1 341499 342005 D COG2825 Outer membrane protein; pyruvate dehydrogenase subunit beta 341499..342005 Rickettsia canadensis str. McKiel 5626847 YP_001492036.1 CDS A1E_01530 NC_009879.1 342140 343606 D catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 342140..343606 Rickettsia canadensis str. McKiel 5626848 YP_001492037.1 CDS A1E_01535 NC_009879.1 343783 344064 D subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G 343783..344064 Rickettsia canadensis str. McKiel 5626849 YP_001492038.1 CDS A1E_01540 NC_009879.1 344228 345277 D subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit B 344228..345277 Rickettsia canadensis str. McKiel 5626877 YP_001492039.1 CDS A1E_01545 NC_009879.1 345270 345917 D Heme exporter protein B 345270..345917 Rickettsia canadensis str. McKiel 5626878 YP_001492040.1 CDS A1E_01550 NC_009879.1 345992 346393 D COG1563 Predicted subunit of the Multisubunit Na+/H+ antiporter; hypothetical protein 345992..346393 Rickettsia canadensis str. McKiel 5626879 YP_001492041.1 CDS A1E_01555 NC_009879.1 346466 346999 D COG0723 Rieske Fe-S protein; ubiquinol-cytochrome c reductase, iron-sulfur subunit 346466..346999 Rickettsia canadensis str. McKiel 5626880 YP_001492042.1 CDS A1E_01560 NC_009879.1 347008 348204 D COG1290 Cytochrome b subunit of the bc complex; cytochrome b 347008..348204 Rickettsia canadensis str. McKiel 5626881 YP_001492043.1 CDS A1E_01565 NC_009879.1 348475 349143 D COG2857 Cytochrome c1; cytochrome c1, heme protein precursor 348475..349143 Rickettsia canadensis str. McKiel 5626722 YP_001492044.1 CDS A1E_01570 NC_009879.1 349815 350318 D COG0071 Molecular chaperone (small heat shock protein); putative monovalent cation/H+ antiporter subunit B 349815..350318 Rickettsia canadensis str. McKiel 5626723 YP_001492045.1 CDS prfB NC_009879.1 350444 351496 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(350444..351496) Rickettsia canadensis str. McKiel 5626724 YP_001492046.1 CDS A1E_01580 NC_009879.1 351834 353636 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 351834..353636 Rickettsia canadensis str. McKiel 5626725 YP_001492047.1 CDS A1E_01585 NC_009879.1 354301 354540 D COG0481 Membrane GTPase LepA; hypothetical protein 354301..354540 Rickettsia canadensis str. McKiel 5626259 YP_001492048.1 CDS A1E_01590 NC_009879.1 356372 357040 R COG0593 ATPase involved in DNA replication initiation; hypothetical protein complement(356372..357040) Rickettsia canadensis str. McKiel 5626260 YP_001492049.1 CDS A1E_01595 NC_009879.1 357249 358304 R COG0628 Predicted permease; hypothetical protein complement(357249..358304) Rickettsia canadensis str. McKiel 5626261 YP_001492050.1 CDS A1E_01600 NC_009879.1 358306 358845 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(358306..358845) Rickettsia canadensis str. McKiel 5626262 YP_001492051.1 CDS rph NC_009879.1 358922 359641 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 358922..359641 Rickettsia canadensis str. McKiel 5626465 YP_001492052.1 CDS rph NC_009879.1 360130 360339 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; ribonuclease PH 360130..360339 Rickettsia canadensis str. McKiel 5626466 YP_001492053.1 CDS groES NC_009879.1 361264 361551 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 361264..361551 Rickettsia canadensis str. McKiel 5626467 YP_001492054.1 CDS groEL NC_009879.1 361581 363224 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 361581..363224 Rickettsia canadensis str. McKiel 5626468 YP_001492055.1 CDS A1E_01625 NC_009879.1 363625 364005 D COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein 363625..364005 Rickettsia canadensis str. McKiel 5626469 YP_001492056.1 CDS groEL NC_009879.1 364741 365274 R COG5342 Invasion protein B, involved in pathogenesis; chaperonin GroEL complement(364741..365274) Rickettsia canadensis str. McKiel 5626861 YP_001492057.1 CDS gltX NC_009879.1 365271 366662 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(365271..366662) Rickettsia canadensis str. McKiel 5626862 YP_001492058.1 CDS A1E_01640 NC_009879.1 366755 367465 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(366755..367465) Rickettsia canadensis str. McKiel 5626863 YP_001492059.1 CDS A1E_01645 NC_009879.1 367641 368408 D COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; 3-demethylubiquinone-9 3-methyltransferase 367641..368408 Rickettsia canadensis str. McKiel 5626864 YP_001492060.1 CDS A1E_01650 NC_009879.1 368952 372380 R Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein; acylglycerophosphoethanolamine acyltransferase complement(368952..372380) Rickettsia canadensis str. McKiel 5626865 YP_001492061.1 CDS A1E_01655 NC_009879.1 372407 372565 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(372407..372565) Rickettsia canadensis str. McKiel 5626840 YP_001492062.1 CDS A1E_01660 NC_009879.1 372645 374189 D propionyl-CoA carboxylase beta chain precursor 372645..374189 Rickettsia canadensis str. McKiel 5626841 YP_001492063.1 CDS A1E_01665 NC_009879.1 374232 374357 D hypothetical protein 374232..374357 Rickettsia canadensis str. McKiel 5626842 YP_001492064.1 CDS A1E_01670 NC_009879.1 374354 374755 D COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); hypothetical protein 374354..374755 Rickettsia canadensis str. McKiel 5626843 YP_001492065.1 CDS A1E_01675 NC_009879.1 374891 376888 D acylglycerophosphoethanolamine acyltransferase 374891..376888 Rickettsia canadensis str. McKiel 5626844 YP_001492066.1 CDS A1E_01680 NC_009879.1 378084 378203 R COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; hypothetical protein complement(378084..378203) Rickettsia canadensis str. McKiel 5626460 YP_001492067.1 CDS ileS NC_009879.1 378459 381698 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase complement(378459..381698) Rickettsia canadensis str. McKiel 5626461 YP_001492068.1 CDS ileS NC_009879.1 382168 382779 R COG5590 Uncharacterized conserved protein; isoleucyl-tRNA synthetase complement(382168..382779) Rickettsia canadensis str. McKiel 5626462 YP_001492069.1 CDS rpsU NC_009879.1 382865 383065 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 382865..383065 Rickettsia canadensis str. McKiel 5626463 YP_001492070.1 CDS A1E_01700 NC_009879.1 383216 383350 R COG0828 Ribosomal protein S21; hypothetical protein complement(383216..383350) Rickettsia canadensis str. McKiel 5626464 YP_001492071.1 CDS A1E_01705 NC_009879.1 383944 385746 D COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; nitrogen regulation protein ntrY 383944..385746 Rickettsia canadensis str. McKiel 5626817 YP_001492072.1 CDS A1E_01710 NC_009879.1 388111 388425 D hypothetical protein 388111..388425 Rickettsia canadensis str. McKiel 5626819 YP_001492073.1 CDS A1E_01715 NC_009879.1 388422 388532 D hypothetical protein 388422..388532 Rickettsia canadensis str. McKiel 5626820 YP_001492074.1 CDS A1E_01720 NC_009879.1 388589 388687 D hypothetical protein 388589..388687 Rickettsia canadensis str. McKiel 5626821 YP_001492075.1 CDS A1E_01725 NC_009879.1 389243 389380 D hypothetical protein 389243..389380 Rickettsia canadensis str. McKiel 5626249 YP_001492076.1 CDS rpsU NC_009879.1 389492 391237 D COG0666 FOG: Ankyrin repeat; 30S ribosomal protein S21 389492..391237 Rickettsia canadensis str. McKiel 5626250 YP_001492077.1 CDS rnpA NC_009879.1 391306 391662 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(391306..391662) Rickettsia canadensis str. McKiel 5626251 YP_001492078.1 CDS rpmH NC_009879.1 391682 391816 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(391682..391816) Rickettsia canadensis str. McKiel 5626252 YP_001492079.1 CDS rplT NC_009879.1 391948 392301 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(391948..392301) Rickettsia canadensis str. McKiel 5626253 YP_001492080.1 CDS rpmI NC_009879.1 392317 392523 R COG0291 Ribosomal protein L35; 50S ribosomal protein L35 complement(392317..392523) Rickettsia canadensis str. McKiel 5626653 YP_001492081.1 CDS rpmI NC_009879.1 392810 393487 D COG0602 Organic radical activating enzymes; 50S ribosomal protein L35 392810..393487 Rickettsia canadensis str. McKiel 5626654 YP_001492082.1 CDS A1E_01760 NC_009879.1 393570 394184 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 393570..394184 Rickettsia canadensis str. McKiel 5626655 YP_001492083.1 CDS A1E_01765 NC_009879.1 394400 394957 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 394400..394957 Rickettsia canadensis str. McKiel 5626656 YP_001492084.1 CDS A1E_01770 NC_009879.1 395240 395416 D COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 395240..395416 Rickettsia canadensis str. McKiel 5626657 YP_001492085.1 CDS A1E_01775 NC_009879.1 395577 396674 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 395577..396674 Rickettsia canadensis str. McKiel 5626476 YP_001492086.1 CDS A1E_01780 NC_009879.1 396688 396903 D hypothetical protein 396688..396903 Rickettsia canadensis str. McKiel 5626477 YP_001492087.1 CDS A1E_01785 NC_009879.1 397585 398814 D hypothetical protein 397585..398814 Rickettsia canadensis str. McKiel 5626478 YP_001492088.1 CDS A1E_01790 NC_009879.1 399150 399293 R hypothetical protein complement(399150..399293) Rickettsia canadensis str. McKiel 5626479 YP_001492089.1 CDS A1E_01795 NC_009879.1 399405 399518 R hypothetical protein complement(399405..399518) Rickettsia canadensis str. McKiel 5626480 YP_001492090.1 CDS A1E_01800 NC_009879.1 399878 400150 R hypothetical protein complement(399878..400150) Rickettsia canadensis str. McKiel 5626530 YP_001492091.1 CDS A1E_01805 NC_009879.1 400155 400316 R hypothetical protein complement(400155..400316) Rickettsia canadensis str. McKiel 5626531 YP_001492092.1 CDS A1E_01810 NC_009879.1 400327 400533 R hypothetical protein complement(400327..400533) Rickettsia canadensis str. McKiel 5626532 YP_001492093.1 CDS A1E_01815 NC_009879.1 400704 402545 R hypothetical protein complement(400704..402545) Rickettsia canadensis str. McKiel 5626533 YP_001492094.1 CDS A1E_01820 NC_009879.1 403657 403941 R hypothetical protein complement(403657..403941) Rickettsia canadensis str. McKiel 5626534 YP_001492095.1 CDS dnaA NC_009879.1 404050 405441 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(404050..405441) Rickettsia canadensis str. McKiel 5626316 YP_001492096.1 CDS A1E_01830 NC_009879.1 405472 405798 R hypothetical protein complement(405472..405798) Rickettsia canadensis str. McKiel 5626317 YP_001492097.1 CDS A1E_01835 NC_009879.1 406123 406386 D hypothetical protein 406123..406386 Rickettsia canadensis str. McKiel 5626318 YP_001492098.1 CDS A1E_01840 NC_009879.1 406399 409758 D hypothetical protein 406399..409758 Rickettsia canadensis str. McKiel 5626319 YP_001492099.1 CDS murE NC_009879.1 409875 411311 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 409875..411311 Rickettsia canadensis str. McKiel 5626320 YP_001492100.1 CDS A1E_01850 NC_009879.1 411460 412968 D hypothetical protein 411460..412968 Rickettsia canadensis str. McKiel 5626254 YP_001492101.1 CDS mraY NC_009879.1 413061 414146 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 413061..414146 Rickettsia canadensis str. McKiel 5626255 YP_001492102.1 CDS A1E_01860 NC_009879.1 414312 415991 D COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; Actin polymerization protein RickA 414312..415991 Rickettsia canadensis str. McKiel 5626256 YP_001492103.1 CDS A1E_01865 NC_009879.1 416516 416677 R COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit; hypothetical protein complement(416516..416677) Rickettsia canadensis str. McKiel 5626257 YP_001492104.1 CDS A1E_01870 NC_009879.1 416760 416924 R COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; succinyl-CoA:3-ketoacid-coenzyme A transferase complement(416760..416924) Rickettsia canadensis str. McKiel 5626258 YP_001492105.1 CDS A1E_01875 NC_009879.1 417034 417243 R succinyl-CoA:3-ketoacid-coenzyme A transferase complement(417034..417243) Rickettsia canadensis str. McKiel 5626239 YP_001492106.1 CDS A1E_01880 NC_009879.1 418000 418290 D hypothetical protein 418000..418290 Rickettsia canadensis str. McKiel 5626240 YP_001492107.1 CDS A1E_01885 NC_009879.1 418398 418607 D COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; hypothetical protein 418398..418607 Rickettsia canadensis str. McKiel 5626241 YP_001492108.1 CDS A1E_01890 NC_009879.1 418671 420788 D COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG 418671..420788 Rickettsia canadensis str. McKiel 5626242 YP_001492109.1 CDS A1E_01895 NC_009879.1 421027 421248 R hypothetical protein complement(421027..421248) Rickettsia canadensis str. McKiel 5626243 YP_001492110.1 CDS A1E_01900 NC_009879.1 421668 422414 R COG1135 ABC-type metal ion transport system, ATPase component; hypothetical protein complement(421668..422414) Rickettsia canadensis str. McKiel 5626296 YP_001492111.1 CDS A1E_01905 NC_009879.1 422411 423916 R virulence factor mviN complement(422411..423916) Rickettsia canadensis str. McKiel 5626297 YP_001492112.1 CDS A1E_01910 NC_009879.1 423983 424096 D COG0728 Uncharacterized membrane protein, putative virulence factor; hypothetical protein 423983..424096 Rickettsia canadensis str. McKiel 5626298 YP_001492113.1 CDS A1E_01915 NC_009879.1 424195 424722 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(424195..424722) Rickettsia canadensis str. McKiel 5626299 YP_001492114.1 CDS A1E_01920 NC_009879.1 424973 425359 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(424973..425359) Rickettsia canadensis str. McKiel 5626300 YP_001492115.1 CDS A1E_01925 NC_009879.1 425461 426078 R COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems; Sco2 protein precursor complement(425461..426078) Rickettsia canadensis str. McKiel 5626337 YP_001492116.1 CDS secD NC_009879.1 426084 427646 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(426084..427646) Rickettsia canadensis str. McKiel 5626338 YP_001492117.1 CDS yajC NC_009879.1 427630 428067 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(427630..428067) Rickettsia canadensis str. McKiel 5626339 YP_001492118.1 CDS A1E_01940 NC_009879.1 430629 431999 R magnesium transporter complement(430629..431999) Rickettsia canadensis str. McKiel 5626341 YP_001492119.1 CDS A1E_01945 NC_009879.1 432412 432534 R COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); hypothetical protein complement(432412..432534) Rickettsia canadensis str. McKiel 5626596 YP_001492120.1 CDS A1E_01950 NC_009879.1 432564 432743 R hypothetical protein complement(432564..432743) Rickettsia canadensis str. McKiel 5626597 YP_001492121.1 CDS A1E_01955 NC_009879.1 432878 433147 D COG1943 Transposase and inactivated derivatives; hypothetical protein 432878..433147 Rickettsia canadensis str. McKiel 5626598 YP_001492122.1 CDS A1E_01960 NC_009879.1 433475 434335 R COG0647 Predicted sugar phosphatases of the HAD superfamily; HAD family hydrolase complement(433475..434335) Rickettsia canadensis str. McKiel 5626312 YP_001492123.1 CDS gyrB NC_009879.1 434443 436869 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 434443..436869 Rickettsia canadensis str. McKiel 5626313 YP_001492124.1 CDS A1E_01970 NC_009879.1 437074 438333 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 437074..438333 Rickettsia canadensis str. McKiel 5626314 YP_001492125.1 CDS rpoZ NC_009879.1 438501 438884 D Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 438501..438884 Rickettsia canadensis str. McKiel 5626315 YP_001492126.1 CDS acpS NC_009879.1 438885 439280 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 438885..439280 Rickettsia canadensis str. McKiel 5625950 YP_001492127.1 CDS A1E_01985 NC_009879.1 439525 440373 R COG0760 Parvulin-like peptidyl-prolyl isomerase; protein export protein PrsA precursor complement(439525..440373) Rickettsia canadensis str. McKiel 5625951 YP_001492128.1 CDS A1E_01990 NC_009879.1 440584 443304 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 440584..443304 Rickettsia canadensis str. McKiel 5625952 YP_001492129.1 CDS A1E_01995 NC_009879.1 443305 443454 D COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); nucleotidyltransferase/HEPN domain-containing protein 443305..443454 Rickettsia canadensis str. McKiel 5625953 YP_001492130.1 CDS A1E_02000 NC_009879.1 444232 444456 D ankyrin repeat-containing protein 444232..444456 Rickettsia canadensis str. McKiel 5625954 YP_001492131.1 CDS A1E_02005 NC_009879.1 444609 444818 D hypothetical protein 444609..444818 Rickettsia canadensis str. McKiel 5626069 YP_001492132.1 CDS A1E_02010 NC_009879.1 444931 445146 D COG0666 FOG: Ankyrin repeat; hypothetical protein 444931..445146 Rickettsia canadensis str. McKiel 5626070 YP_001492133.1 CDS A1E_02015 NC_009879.1 445734 445877 D COG0286 Type I restriction-modification system methyltransferase subunit; Type I restriction-modification system, M subunit 445734..445877 Rickettsia canadensis str. McKiel 5626072 YP_001492134.1 CDS A1E_02020 NC_009879.1 445802 446044 D Type I restriction-modification system, M subunit 445802..446044 Rickettsia canadensis str. McKiel 5626443 YP_001492135.1 CDS A1E_02025 NC_009879.1 446915 447103 R COG0286 Type I restriction-modification system methyltransferase subunit; hypothetical protein complement(446915..447103) Rickettsia canadensis str. McKiel 5626444 YP_001492136.1 CDS A1E_02030 NC_009879.1 447424 448818 D COG0591 Na+/proline symporter; Sodium/pantothenate symporter 447424..448818 Rickettsia canadensis str. McKiel 5626445 YP_001492137.1 CDS uvrC NC_009879.1 449353 451269 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(449353..451269) Rickettsia canadensis str. McKiel 5626446 YP_001492138.1 CDS A1E_02040 NC_009879.1 451351 451884 R hypothetical protein complement(451351..451884) Rickettsia canadensis str. McKiel 5626447 YP_001492139.1 CDS A1E_02045 NC_009879.1 452001 452111 R COG2847 Uncharacterized protein conserved in bacteria; hypothetical protein complement(452001..452111) Rickettsia canadensis str. McKiel 5626301 YP_001492140.1 CDS A1E_02050 NC_009879.1 452588 453118 R COG0350 Methylated DNA-protein cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase complement(452588..453118) Rickettsia canadensis str. McKiel 5626302 YP_001492141.1 CDS A1E_02055 NC_009879.1 454363 454545 R COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Type I site-specific restriction-modification system, R (restriction) subunit complement(454363..454545) Rickettsia canadensis str. McKiel 5626303 YP_001492142.1 CDS A1E_02060 NC_009879.1 456406 456855 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 456406..456855 Rickettsia canadensis str. McKiel 5626304 YP_001492143.1 CDS mraW NC_009879.1 456855 457781 D COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW 456855..457781 Rickettsia canadensis str. McKiel 5626305 YP_001492144.1 CDS A1E_02070 NC_009879.1 457784 458173 D COG5462 Predicted secreted (periplasmic) protein; cell division protein FtsL 457784..458173 Rickettsia canadensis str. McKiel 5626013 YP_001492145.1 CDS A1E_02075 NC_009879.1 458264 459949 D penicillin-binding protein 458264..459949 Rickettsia canadensis str. McKiel 5626014 YP_001492146.1 CDS A1E_02080 NC_009879.1 460379 460900 D COG0768 Cell division protein FtsI/penicillin-binding protein 2; hypothetical protein 460379..460900 Rickettsia canadensis str. McKiel 5626015 YP_001492147.1 CDS A1E_02085 NC_009879.1 460890 462671 D penicillin-binding protein 460890..462671 Rickettsia canadensis str. McKiel 5626016 YP_001492148.1 CDS A1E_02090 NC_009879.1 462710 462850 D hypothetical protein 462710..462850 Rickettsia canadensis str. McKiel 5626017 YP_001492149.1 CDS A1E_02095 NC_009879.1 463165 463344 D hypothetical protein 463165..463344 Rickettsia canadensis str. McKiel 5626331 YP_001492150.1 CDS A1E_02100 NC_009879.1 463781 464758 D COG0768 Cell division protein FtsI/penicillin-binding protein 2; hypothetical protein 463781..464758 Rickettsia canadensis str. McKiel 5626332 YP_001492151.1 CDS A1E_02105 NC_009879.1 465108 466859 R COG1357 Uncharacterized low-complexity proteins; hypothetical protein complement(465108..466859) Rickettsia canadensis str. McKiel 5626333 YP_001492152.1 CDS A1E_02110 NC_009879.1 466846 468273 R COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; nitrogen assimilation regulatory protein NtrX complement(466846..468273) Rickettsia canadensis str. McKiel 5626334 YP_001492153.1 CDS A1E_02115 NC_009879.1 468487 468753 D subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit F 468487..468753 Rickettsia canadensis str. McKiel 5626335 YP_001492154.1 CDS A1E_02120 NC_009879.1 468896 470023 D Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 468896..470023 Rickettsia canadensis str. McKiel 5626336 YP_001492155.1 CDS A1E_02125 NC_009879.1 470237 470419 D hypothetical protein 470237..470419 Rickettsia canadensis str. McKiel 5626105 YP_001492156.1 CDS A1E_02130 NC_009879.1 470412 470531 D hypothetical protein 470412..470531 Rickettsia canadensis str. McKiel 5626106 YP_001492157.1 CDS A1E_02135 NC_009879.1 470997 471071 D hypothetical protein 470997..471071 Rickettsia canadensis str. McKiel 5626107 YP_001492158.1 CDS A1E_02140 NC_009879.1 471696 471911 D hypothetical protein 471696..471911 Rickettsia canadensis str. McKiel 5626108 YP_001492159.1 CDS A1E_02145 NC_009879.1 471901 472050 D hypothetical protein 471901..472050 Rickettsia canadensis str. McKiel 5626109 YP_001492160.1 CDS A1E_02150 NC_009879.1 472038 472241 D COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; hypothetical protein 472038..472241 Rickettsia canadensis str. McKiel 5626110 YP_001492161.1 CDS A1E_02155 NC_009879.1 472492 473823 D COG0477 Permeases of the major facilitator superfamily; proline/betaine transporter 472492..473823 Rickettsia canadensis str. McKiel 5626018 YP_001492162.1 CDS A1E_02160 NC_009879.1 473820 474467 R hypothetical protein complement(473820..474467) Rickettsia canadensis str. McKiel 5626019 YP_001492164.1 CDS A1E_02170 NC_009879.1 476156 476395 R hypothetical protein complement(476156..476395) Rickettsia canadensis str. McKiel 5626022 YP_001492165.1 CDS A1E_02175 NC_009879.1 476698 476994 R hypothetical protein complement(476698..476994) Rickettsia canadensis str. McKiel 5626083 YP_001492166.1 CDS A1E_02180 NC_009879.1 477733 477912 D COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein 477733..477912 Rickettsia canadensis str. McKiel 5626084 YP_001492167.1 CDS A1E_02185 NC_009879.1 477924 479159 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 477924..479159 Rickettsia canadensis str. McKiel 5626085 YP_001492168.1 CDS A1E_02190 NC_009879.1 479982 480158 D COG0162 Tyrosyl-tRNA synthetase; hypothetical protein 479982..480158 Rickettsia canadensis str. McKiel 5626086 YP_001492169.1 CDS A1E_02195 NC_009879.1 480266 481120 D COG1189 Predicted rRNA methylase; tyrosyl-tRNA synthetase 480266..481120 Rickettsia canadensis str. McKiel 5626087 YP_001492170.1 CDS A1E_02200 NC_009879.1 481400 481777 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 481400..481777 Rickettsia canadensis str. McKiel 5626088 YP_001492171.1 CDS nusA NC_009879.1 481900 483411 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 481900..483411 Rickettsia canadensis str. McKiel 5626395 YP_001492172.1 CDS infB NC_009879.1 483625 486126 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 483625..486126 Rickettsia canadensis str. McKiel 5626396 YP_001492173.1 CDS A1E_02215 NC_009879.1 486434 488014 D COG0532 Translation initiation factor 2 (IF-2; GTPase); hypothetical protein 486434..488014 Rickettsia canadensis str. McKiel 5626397 YP_001492174.1 CDS infB NC_009879.1 488043 488723 R COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; translation initiation factor IF-2 complement(488043..488723) Rickettsia canadensis str. McKiel 5626398 YP_001492175.1 CDS recO NC_009879.1 488806 489531 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(488806..489531) Rickettsia canadensis str. McKiel 5626399 YP_001492176.1 CDS recO NC_009879.1 489730 490062 R COG0191 Fructose/tagatose bisphosphate aldolase; DNA repair protein RecO complement(489730..490062) Rickettsia canadensis str. McKiel 5626400 YP_001492177.1 CDS A1E_02235 NC_009879.1 490059 491399 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(490059..491399) Rickettsia canadensis str. McKiel 5626748 YP_001492178.1 CDS A1E_02240 NC_009879.1 491538 492110 R COG0742 N6-adenine-specific methylase; N6-adenine-specific methylase complement(491538..492110) Rickettsia canadensis str. McKiel 5626749 YP_001492179.1 CDS A1E_02245 NC_009879.1 492119 494989 R COG1357 Uncharacterized low-complexity proteins; hypothetical protein complement(492119..494989) Rickettsia canadensis str. McKiel 5626750 YP_001492180.1 CDS A1E_02250 NC_009879.1 495040 495729 R COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; repair protein complement(495040..495729) Rickettsia canadensis str. McKiel 5626751 YP_001492181.1 CDS A1E_02255 NC_009879.1 495922 496068 D hypothetical protein 495922..496068 Rickettsia canadensis str. McKiel 5626752 YP_001492182.1 CDS A1E_02260 NC_009879.1 496497 496643 D COG0814 Amino acid permeases; hypothetical protein 496497..496643 Rickettsia canadensis str. McKiel 5626753 YP_001492183.1 CDS A1E_02265 NC_009879.1 496743 498227 R unwinds double stranded DNA; replicative DNA helicase complement(496743..498227) Rickettsia canadensis str. McKiel 5626590 YP_001492184.1 CDS A1E_02270 NC_009879.1 498715 499350 R COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; aromatic acid decarboxylase complement(498715..499350) Rickettsia canadensis str. McKiel 5626591 YP_001492185.1 CDS A1E_02275 NC_009879.1 499345 501291 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 499345..501291 Rickettsia canadensis str. McKiel 5626592 YP_001492186.1 CDS A1E_02280 NC_009879.1 501787 501903 R COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; hypothetical protein complement(501787..501903) Rickettsia canadensis str. McKiel 5626593 YP_001492187.1 CDS A1E_02285 NC_009879.1 502061 503053 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 502061..503053 Rickettsia canadensis str. McKiel 5626594 YP_001492188.1 CDS A1E_02290 NC_009879.1 503168 504733 D COG0113 Delta-aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase 503168..504733 Rickettsia canadensis str. McKiel 5626595 YP_001492189.1 CDS A1E_02295 NC_009879.1 504723 506093 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(504723..506093) Rickettsia canadensis str. McKiel 5626600 YP_001492190.1 CDS A1E_02300 NC_009879.1 506111 506275 D hypothetical protein 506111..506275 Rickettsia canadensis str. McKiel 5626601 YP_001492191.1 CDS A1E_02305 NC_009879.1 506505 506684 D COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); transposase 506505..506684 Rickettsia canadensis str. McKiel 5626602 YP_001492192.1 CDS A1E_02310 NC_009879.1 507004 507237 D hypothetical protein 507004..507237 Rickettsia canadensis str. McKiel 5626603 YP_001492193.1 CDS A1E_02315 NC_009879.1 507267 507389 D hypothetical protein 507267..507389 Rickettsia canadensis str. McKiel 5626604 YP_001492194.1 CDS A1E_02320 NC_009879.1 507737 508609 D hypothetical protein 507737..508609 Rickettsia canadensis str. McKiel 5626605 YP_001492195.1 CDS A1E_02325 NC_009879.1 508865 508969 D COG1943 Transposase and inactivated derivatives; hypothetical protein 508865..508969 Rickettsia canadensis str. McKiel 5626760 YP_001492196.1 CDS A1E_02330 NC_009879.1 509686 510792 D COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; hypothetical protein 509686..510792 Rickettsia canadensis str. McKiel 5626761 YP_001492197.1 CDS A1E_02335 NC_009879.1 510902 512134 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 510902..512134 Rickettsia canadensis str. McKiel 5626762 YP_001492198.1 CDS A1E_02340 NC_009879.1 512223 512624 D COG0822 NifU homolog involved in Fe-S cluster formation; scaffold protein 512223..512624 Rickettsia canadensis str. McKiel 5626763 YP_001492199.1 CDS A1E_02345 NC_009879.1 512621 512953 D COG0316 Uncharacterized conserved protein; Iron-sulfur cluster assembly accessory protein 512621..512953 Rickettsia canadensis str. McKiel 5626764 YP_001492200.1 CDS A1E_02350 NC_009879.1 513083 514399 D COG0531 Amino acid transporters; putrescine-ornithine antiporter 513083..514399 Rickettsia canadensis str. McKiel 5626765 YP_001492201.1 CDS A1E_02355 NC_009879.1 514480 516357 D COG0006 Xaa-Pro aminopeptidase; hypothetical protein 514480..516357 Rickettsia canadensis str. McKiel 5626423 YP_001492202.1 CDS A1E_02360 NC_009879.1 516744 517727 R octaprenyl-diphosphate synthase complement(516744..517727) Rickettsia canadensis str. McKiel 5626426 YP_001492203.1 CDS A1E_02365 NC_009879.1 517839 519500 R COG0142 Geranylgeranyl pyrophosphate synthase; hypothetical protein complement(517839..519500) Rickettsia canadensis str. McKiel 5626213 YP_001492204.1 CDS A1E_02370 NC_009879.1 519660 521171 R COG3202 ATP/ADP translocase; ADP,ATP carrier protein complement(519660..521171) Rickettsia canadensis str. McKiel 5626214 YP_001492205.1 CDS A1E_02375 NC_009879.1 521420 521797 R COG1943 Transposase and inactivated derivatives; transposase IS200-family protein complement(521420..521797) Rickettsia canadensis str. McKiel 5626215 YP_001492206.1 CDS A1E_02380 NC_009879.1 522057 523307 D COG0477 Permeases of the major facilitator superfamily; ampG protein 522057..523307 Rickettsia canadensis str. McKiel 5626216 YP_001492207.1 CDS A1E_02385 NC_009879.1 523773 524414 D lysine efflux permease 523773..524414 Rickettsia canadensis str. McKiel 5626811 YP_001492208.1 CDS A1E_02390 NC_009879.1 524392 525072 D hypothetical protein 524392..525072 Rickettsia canadensis str. McKiel 5626812 YP_001492209.1 CDS A1E_02395 NC_009879.1 525059 525841 D COG1279 Lysine efflux permease; hypothetical protein 525059..525841 Rickettsia canadensis str. McKiel 5626813 YP_001492210.1 CDS A1E_02400 NC_009879.1 525834 526847 D COG0457 FOG: TPR repeat; hypothetical protein 525834..526847 Rickettsia canadensis str. McKiel 5626814 YP_001492211.1 CDS A1E_02405 NC_009879.1 527021 527740 R hypothetical protein complement(527021..527740) Rickettsia canadensis str. McKiel 5626815 YP_001492212.1 CDS A1E_02410 NC_009879.1 527861 528004 D COG2945 Predicted hydrolase of the alpha/beta superfamily; hypothetical protein 527861..528004 Rickettsia canadensis str. McKiel 5626816 YP_001492213.1 CDS A1E_02415 NC_009879.1 528159 528599 R COG5622 Protein required for attachment to host cells; hypothetical protein complement(528159..528599) Rickettsia canadensis str. McKiel 5625981 YP_001492214.1 CDS A1E_02420 NC_009879.1 528641 529228 R COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; scaffold protein complement(528641..529228) Rickettsia canadensis str. McKiel 5625982 YP_001492215.1 CDS A1E_02425 NC_009879.1 529456 530448 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 529456..530448 Rickettsia canadensis str. McKiel 5625983 YP_001492216.1 CDS A1E_02430 NC_009879.1 531967 532101 R COG0180 Tryptophanyl-tRNA synthetase; hypothetical protein complement(531967..532101) Rickettsia canadensis str. McKiel 5625985 YP_001492217.1 CDS hemC NC_009879.1 532198 533103 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(532198..533103) Rickettsia canadensis str. McKiel 5625915 YP_001492218.1 CDS A1E_02440 NC_009879.1 533100 533324 R microcin C7 resistance protein complement(533100..533324) Rickettsia canadensis str. McKiel 5625916 YP_001492219.1 CDS A1E_02445 NC_009879.1 533531 533659 R hypothetical protein complement(533531..533659) Rickettsia canadensis str. McKiel 5625917 YP_001492220.1 CDS A1E_02450 NC_009879.1 533637 533792 R hypothetical protein complement(533637..533792) Rickettsia canadensis str. McKiel 5625918 YP_001492221.1 CDS A1E_02455 NC_009879.1 533819 533959 D COG0181 Porphobilinogen deaminase; hypothetical protein 533819..533959 Rickettsia canadensis str. McKiel 5625919 YP_001492222.1 CDS A1E_02460 NC_009879.1 534261 534542 R alkaline phosphatase synthesis sensor protein phor (phor) complement(534261..534542) Rickettsia canadensis str. McKiel 5625920 YP_001492223.1 CDS A1E_02465 NC_009879.1 536315 536452 R COG0642 Signal transduction histidine kinase; hypothetical protein complement(536315..536452) Rickettsia canadensis str. McKiel 5626375 YP_001492224.1 CDS A1E_02470 NC_009879.1 536514 537344 R COG0354 Predicted aminomethyltransferase related to GcvT; glycine cleavage T-protein complement(536514..537344) Rickettsia canadensis str. McKiel 5626376 YP_001492225.1 CDS A1E_02475 NC_009879.1 537460 538251 D COG1723 Uncharacterized conserved protein; hypothetical protein 537460..538251 Rickettsia canadensis str. McKiel 5626377 YP_001492226.1 CDS A1E_02480 NC_009879.1 538262 539116 D COG0349 Ribonuclease D; ribonuclease D 538262..539116 Rickettsia canadensis str. McKiel 5626378 YP_001492227.1 CDS hemC NC_009879.1 539212 539751 R COG0212 5-formyltetrahydrofolate cyclo-ligase; porphobilinogen deaminase complement(539212..539751) Rickettsia canadensis str. McKiel 5626379 YP_001492228.1 CDS A1E_02490 NC_009879.1 539784 541163 R Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(539784..541163) Rickettsia canadensis str. McKiel 5626380 YP_001492229.1 CDS A1E_02495 NC_009879.1 541323 541895 R biotin synthesis protein BioC complement(541323..541895) Rickettsia canadensis str. McKiel 5626417 YP_001492230.1 CDS A1E_02500 NC_009879.1 542226 542864 R COG0500 SAM-dependent methyltransferases; hypothetical protein complement(542226..542864) Rickettsia canadensis str. McKiel 5626418 YP_001492231.1 CDS A1E_02505 NC_009879.1 542885 543652 R hypothetical protein complement(542885..543652) Rickettsia canadensis str. McKiel 5626419 YP_001492232.1 CDS A1E_02510 NC_009879.1 545051 545287 R dihydrolipoamide dehydrogenase complement(545051..545287) Rickettsia canadensis str. McKiel 5626420 YP_001492233.1 CDS rpmJ NC_009879.1 545454 545579 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 545454..545579 Rickettsia canadensis str. McKiel 5626421 YP_001492234.1 CDS A1E_02520 NC_009879.1 545695 546453 D COG0217 Uncharacterized conserved protein; hypothetical protein 545695..546453 Rickettsia canadensis str. McKiel 5626422 YP_001492235.1 CDS A1E_02525 NC_009879.1 546453 547199 D UDP-N-acetylglucosamine pyrophosphorylase 546453..547199 Rickettsia canadensis str. McKiel 5626794 YP_001492236.1 CDS A1E_02535 NC_009879.1 547555 547800 R hypothetical protein complement(547555..547800) Rickettsia canadensis str. McKiel 5626796 YP_001492237.1 CDS A1E_02540 NC_009879.1 548279 548389 D COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); hypothetical protein 548279..548389 Rickettsia canadensis str. McKiel 5626797 YP_001492238.1 CDS A1E_02545 NC_009879.1 548565 548828 R hypothetical protein complement(548565..548828) Rickettsia canadensis str. McKiel 5626798 YP_001492239.1 CDS A1E_02550 NC_009879.1 549276 549383 D COG1694 Predicted pyrophosphatase; hypothetical protein 549276..549383 Rickettsia canadensis str. McKiel 5625881 YP_001492240.1 CDS A1E_02555 NC_009879.1 549394 550422 R catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase complement(549394..550422) Rickettsia canadensis str. McKiel 5625882 YP_001492241.1 CDS A1E_02560 NC_009879.1 550696 550860 R hypothetical protein complement(550696..550860) Rickettsia canadensis str. McKiel 5625883 YP_001492242.1 CDS A1E_02565 NC_009879.1 551825 552034 R COG0474 Cation transport ATPase; hypothetical protein complement(551825..552034) Rickettsia canadensis str. McKiel 5625884 YP_001492243.1 CDS clpP NC_009879.1 552624 553229 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(552624..553229) Rickettsia canadensis str. McKiel 5625886 YP_001492244.1 CDS rpsA NC_009879.1 553367 555073 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(553367..555073) Rickettsia canadensis str. McKiel 5626497 YP_001492245.1 CDS cmk NC_009879.1 555226 555882 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(555226..555882) Rickettsia canadensis str. McKiel 5626498 YP_001492246.1 CDS A1E_02585 NC_009879.1 556444 556833 D hypothetical protein 556444..556833 Rickettsia canadensis str. McKiel 5626500 YP_001492247.1 CDS A1E_02590 NC_009879.1 557416 557580 D hypothetical protein 557416..557580 Rickettsia canadensis str. McKiel 5626894 YP_001492248.1 CDS A1E_02595 NC_009879.1 557495 557692 D COG0283 Cytidylate kinase; hypothetical protein 557495..557692 Rickettsia canadensis str. McKiel 5626895 YP_001492249.1 CDS A1E_02600 NC_009879.1 557898 558209 D COG2801 Transposase and inactivated derivatives; integrase catalytic subunit 557898..558209 Rickettsia canadensis str. McKiel 5626896 YP_001492250.1 CDS A1E_02605 NC_009879.1 558971 559678 D hypothetical protein 558971..559678 Rickettsia canadensis str. McKiel 5626897 YP_001492251.1 CDS A1E_02610 NC_009879.1 559707 560798 R COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; hypothetical protein complement(559707..560798) Rickettsia canadensis str. McKiel 5626898 YP_001492252.1 CDS A1E_02615 NC_009879.1 560805 562115 R proline/betaine transporter complement(560805..562115) Rickettsia canadensis str. McKiel 5626899 YP_001492253.1 CDS A1E_02620 NC_009879.1 562214 562435 R conjugal transfer protein TraD complement(562214..562435) Rickettsia canadensis str. McKiel 5626716 YP_001492254.1 CDS A1E_02625 NC_009879.1 563083 563202 D conjugal transfer protein TraA 563083..563202 Rickettsia canadensis str. McKiel 5626717 YP_001492255.1 CDS A1E_02630 NC_009879.1 563202 563384 D conjugal transfer protein TraA 563202..563384 Rickettsia canadensis str. McKiel 5626718 YP_001492256.1 CDS A1E_02635 NC_009879.1 563521 563775 D conjugal transfer protein TraA 563521..563775 Rickettsia canadensis str. McKiel 5626719 YP_001492257.1 CDS A1E_02640 NC_009879.1 564150 564296 D conjugal transfer protein TraA 564150..564296 Rickettsia canadensis str. McKiel 5626720 YP_001492258.1 CDS A1E_02645 NC_009879.1 564286 564438 D hypothetical protein 564286..564438 Rickettsia canadensis str. McKiel 5626721 YP_001492259.1 CDS A1E_02650 NC_009879.1 564556 564789 D COG0477 Permeases of the major facilitator superfamily; conjugal transfer protein TraA 564556..564789 Rickettsia canadensis str. McKiel 5626658 YP_001492260.1 CDS A1E_02655 NC_009879.1 565561 566427 D conjugal transfer protein TraA 565561..566427 Rickettsia canadensis str. McKiel 5626659 YP_001492261.1 CDS A1E_02660 NC_009879.1 566393 566539 R putative conjugative transfer protein TraD complement(566393..566539) Rickettsia canadensis str. McKiel 5626660 YP_001492262.1 CDS A1E_02665 NC_009879.1 566600 566956 R COG0358 DNA primase (bacterial type); putative conjugative transfer protein TraD complement(566600..566956) Rickettsia canadensis str. McKiel 5626661 YP_001492263.1 CDS A1E_02670 NC_009879.1 567115 567324 R TPR repeat-containing protein complement(567115..567324) Rickettsia canadensis str. McKiel 5626662 YP_001492264.1 CDS A1E_02675 NC_009879.1 567420 567593 R TPR repeat-containing protein complement(567420..567593) Rickettsia canadensis str. McKiel 5626663 YP_001492265.1 CDS A1E_02680 NC_009879.1 567678 567809 R hypothetical protein complement(567678..567809) Rickettsia canadensis str. McKiel 5626099 YP_001492266.1 CDS A1E_02685 NC_009879.1 568354 568881 R conjugative transfer protein TraG complement(568354..568881) Rickettsia canadensis str. McKiel 5626100 YP_001492267.1 CDS A1E_02690 NC_009879.1 569712 569855 R hypothetical protein complement(569712..569855) Rickettsia canadensis str. McKiel 5626101 YP_001492268.1 CDS A1E_02695 NC_009879.1 570724 570942 R hypothetical protein complement(570724..570942) Rickettsia canadensis str. McKiel 5626102 YP_001492269.1 CDS A1E_02700 NC_009879.1 571020 571616 D hypothetical protein 571020..571616 Rickettsia canadensis str. McKiel 5626103 YP_001492270.1 CDS A1E_02705 NC_009879.1 571895 572290 R hypothetical protein complement(571895..572290) Rickettsia canadensis str. McKiel 5626104 YP_001492271.1 CDS A1E_02710 NC_009879.1 573827 574039 R putative conjugative transfer protein TraD complement(573827..574039) Rickettsia canadensis str. McKiel 5625875 YP_001492272.1 CDS A1E_02715 NC_009879.1 574374 574595 R F pilus assembly protein TraB complement(574374..574595) Rickettsia canadensis str. McKiel 5625876 YP_001492273.1 CDS A1E_02720 NC_009879.1 574965 575180 R COG0457 FOG: TPR repeat; hypothetical protein complement(574965..575180) Rickettsia canadensis str. McKiel 5625877 YP_001492274.1 CDS A1E_02725 NC_009879.1 575746 575892 R COG0776 Bacterial nucleoid DNA-binding protein; hypothetical protein complement(575746..575892) Rickettsia canadensis str. McKiel 5625878 YP_001492275.1 CDS cmk NC_009879.1 575892 576809 R COG0616 Periplasmic serine proteases (ClpP class); cytidylate kinase complement(575892..576809) Rickettsia canadensis str. McKiel 5625879 YP_001492276.1 CDS rho NC_009879.1 577054 578430 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(577054..578430) Rickettsia canadensis str. McKiel 5625880 YP_001492277.1 CDS A1E_02740 NC_009879.1 578946 580268 R COG0500 SAM-dependent methyltransferases; putative methyltransferase complement(578946..580268) Rickettsia canadensis str. McKiel 5626557 YP_001492278.1 CDS rho NC_009879.1 580278 582035 R COG0608 Single-stranded DNA-specific exonuclease; transcription termination factor Rho complement(580278..582035) Rickettsia canadensis str. McKiel 5626558 YP_001492279.1 CDS prfA NC_009879.1 582212 583279 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(582212..583279) Rickettsia canadensis str. McKiel 5626559 YP_001492280.1 CDS A1E_02755 NC_009879.1 583562 584818 R COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; branched-chain alpha-keto acid dehydrogenase subunit E2 complement(583562..584818) Rickettsia canadensis str. McKiel 5626560 YP_001492281.1 CDS infC NC_009879.1 585057 585500 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(585057..585500) Rickettsia canadensis str. McKiel 5626561 YP_001492282.1 CDS A1E_02765 NC_009879.1 585675 586010 R hypothetical protein complement(585675..586010) Rickettsia canadensis str. McKiel 5626562 YP_001492283.1 CDS A1E_02770 NC_009879.1 585997 586170 R hypothetical protein complement(585997..586170) Rickettsia canadensis str. McKiel 5626866 YP_001492284.1 CDS A1E_02775 NC_009879.1 586361 586615 R hypothetical protein complement(586361..586615) Rickettsia canadensis str. McKiel 5626867 YP_001492285.1 CDS A1E_02780 NC_009879.1 586909 587097 R COG5346 Predicted membrane protein; hypothetical protein complement(586909..587097) Rickettsia canadensis str. McKiel 5626868 YP_001492286.1 CDS A1E_02785 NC_009879.1 587181 587960 R biotin--protein ligase complement(587181..587960) Rickettsia canadensis str. McKiel 5626869 YP_001492287.1 CDS A1E_02805 NC_009879.1 589016 589189 D COG0340 Biotin-(acetyl-CoA carboxylase) ligase; hypothetical protein 589016..589189 Rickettsia canadensis str. McKiel 5626870 YP_001492288.1 CDS A1E_02815 NC_009879.1 589885 590514 R COG0605 Superoxide dismutase; superoxide dismutase complement(589885..590514) Rickettsia canadensis str. McKiel 5626871 YP_001492289.1 CDS A1E_02820 NC_009879.1 590605 591909 R COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase complement(590605..591909) Rickettsia canadensis str. McKiel 5626448 YP_001492290.1 CDS A1E_02825 NC_009879.1 591911 592471 R BioY family protein complement(591911..592471) Rickettsia canadensis str. McKiel 5626449 YP_001492291.1 CDS A1E_02830 NC_009879.1 592724 593053 D hypothetical protein 592724..593053 Rickettsia canadensis str. McKiel 5626450 YP_001492292.1 CDS A1E_02835 NC_009879.1 593121 593249 D COG4285 Uncharacterized conserved protein; hypothetical protein 593121..593249 Rickettsia canadensis str. McKiel 5626451 YP_001492293.1 CDS infC NC_009879.1 593268 593936 R COG0625 Glutathione S-transferase; translation initiation factor IF-3 complement(593268..593936) Rickettsia canadensis str. McKiel 5626452 YP_001492294.1 CDS A1E_02845 NC_009879.1 594669 597305 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 594669..597305 Rickettsia canadensis str. McKiel 5626453 YP_001492295.1 CDS A1E_02850 NC_009879.1 597692 597814 R hypothetical protein complement(597692..597814) Rickettsia canadensis str. McKiel 5626163 YP_001492296.1 CDS A1E_02855 NC_009879.1 597879 597959 R hypothetical protein complement(597879..597959) Rickettsia canadensis str. McKiel 5626164 YP_001492297.1 CDS A1E_02860 NC_009879.1 598360 598626 R hypothetical protein complement(598360..598626) Rickettsia canadensis str. McKiel 5626165 YP_001492298.1 CDS A1E_02865 NC_009879.1 599182 600789 D hypothetical protein 599182..600789 Rickettsia canadensis str. McKiel 5626166 YP_001492299.1 CDS A1E_02870 NC_009879.1 601306 601401 D hypothetical protein 601306..601401 Rickettsia canadensis str. McKiel 5626167 YP_001492300.1 CDS A1E_02875 NC_009879.1 601920 602000 R hypothetical protein complement(601920..602000) Rickettsia canadensis str. McKiel 5626168 YP_001492301.1 CDS A1E_02880 NC_009879.1 602073 602174 R COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; hypothetical protein complement(602073..602174) Rickettsia canadensis str. McKiel 5626799 YP_001492302.1 CDS A1E_02885 NC_009879.1 602289 603011 R COG1496 Uncharacterized conserved protein; hypothetical protein complement(602289..603011) Rickettsia canadensis str. McKiel 5626800 YP_001492303.1 CDS A1E_02890 NC_009879.1 603010 603843 D COG0174 Glutamine synthetase; glutamine synthetase 603010..603843 Rickettsia canadensis str. McKiel 5626801 YP_001492304.1 CDS A1E_02895 NC_009879.1 603991 604818 R COG1295 Predicted membrane protein; hypothetical protein complement(603991..604818) Rickettsia canadensis str. McKiel 5626802 YP_001492305.1 CDS A1E_02900 NC_009879.1 605440 605832 D transcriptional regulator 605440..605832 Rickettsia canadensis str. McKiel 5626803 YP_001492306.1 CDS A1E_02905 NC_009879.1 606064 608943 R COG1396 Predicted transcriptional regulators; cell surface antigen complement(606064..608943) Rickettsia canadensis str. McKiel 5626804 YP_001492307.1 CDS A1E_02910 NC_009879.1 609255 610790 R COG3202 ATP/ADP translocase; pyruvate phosphate dikinase complement(609255..610790) Rickettsia canadensis str. McKiel 5626342 YP_001492308.1 CDS truB NC_009879.1 610876 611757 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 610876..611757 Rickettsia canadensis str. McKiel 5626343 YP_001492309.1 CDS rpsO NC_009879.1 611922 612197 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 611922..612197 Rickettsia canadensis str. McKiel 5626344 YP_001492310.1 CDS A1E_02925 NC_009879.1 612464 614707 D COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 612464..614707 Rickettsia canadensis str. McKiel 5626345 YP_001492311.1 CDS A1E_02930 NC_009879.1 614847 615806 D COG0794 Predicted sugar phosphate isomerase involved in capsule formation; KpsF protein 614847..615806 Rickettsia canadensis str. McKiel 5626346 YP_001492312.1 CDS A1E_02935 NC_009879.1 615845 616411 D COG5375 Uncharacterized protein conserved in bacteria; hypothetical protein 615845..616411 Rickettsia canadensis str. McKiel 5626347 YP_001492313.1 CDS A1E_02940 NC_009879.1 616377 616814 D COG1934 Uncharacterized protein conserved in bacteria; hypothetical protein 616377..616814 Rickettsia canadensis str. McKiel 5626123 YP_001492314.1 CDS A1E_02945 NC_009879.1 616962 617684 D COG1137 ABC-type (unclassified) transport system, ATPase component; ABC transporter ATP-binding protein 616962..617684 Rickettsia canadensis str. McKiel 5626124 YP_001492315.1 CDS A1E_02950 NC_009879.1 617885 619432 D COG1109 Phosphomannomutase; polynucleotide phosphorylase/polyadenylase 617885..619432 Rickettsia canadensis str. McKiel 5626125 YP_001492316.1 CDS miaA NC_009879.1 619429 620406 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 619429..620406 Rickettsia canadensis str. McKiel 5626126 YP_001492317.1 CDS miaA NC_009879.1 621037 623904 R COG0593 ATPase involved in DNA replication initiation; tRNA delta(2)-isopentenylpyrophosphate transferase complement(621037..623904) Rickettsia canadensis str. McKiel 5626127 YP_001492318.1 CDS nrdF NC_009879.1 624006 624980 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(624006..624980) Rickettsia canadensis str. McKiel 5626128 YP_001492319.1 CDS A1E_02970 NC_009879.1 625226 627049 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(625226..627049) Rickettsia canadensis str. McKiel 5625921 YP_001492320.1 CDS A1E_02975 NC_009879.1 627244 627342 R hypothetical protein complement(627244..627342) Rickettsia canadensis str. McKiel 5625922 YP_001492321.1 CDS A1E_02980 NC_009879.1 627951 628109 R COG0209 Ribonucleotide reductase, alpha subunit; hypothetical protein complement(627951..628109) Rickettsia canadensis str. McKiel 5625923 YP_001492322.1 CDS A1E_02985 NC_009879.1 629165 630178 D COG0492 Thioredoxin reductase; thioredoxin reductase 629165..630178 Rickettsia canadensis str. McKiel 5625924 YP_001492323.1 CDS A1E_02990 NC_009879.1 630312 631193 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 630312..631193 Rickettsia canadensis str. McKiel 5625925 YP_001492324.1 CDS A1E_02995 NC_009879.1 631337 631915 R sigma(54) modulation protein complement(631337..631915) Rickettsia canadensis str. McKiel 5625926 YP_001492325.1 CDS A1E_03000 NC_009879.1 633581 633769 R COG1544 Ribosome-associated protein Y (PSrp-1); hypothetical protein complement(633581..633769) Rickettsia canadensis str. McKiel 5626624 YP_001492326.1 CDS A1E_03005 NC_009879.1 634191 634358 D hypothetical protein 634191..634358 Rickettsia canadensis str. McKiel 5626625 YP_001492327.1 CDS A1E_03010 NC_009879.1 634436 634642 D COG5525 Bacteriophage tail assembly protein; hypothetical protein 634436..634642 Rickettsia canadensis str. McKiel 5626626 YP_001492328.1 CDS A1E_03015 NC_009879.1 634997 637333 R COG0466 ATP-dependent Lon protease, bacterial type; ribonucleotide-diphosphate reductase subunit alpha complement(634997..637333) Rickettsia canadensis str. McKiel 5626627 YP_001492329.1 CDS A1E_03020 NC_009879.1 637417 638418 D catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 637417..638418 Rickettsia canadensis str. McKiel 5626545 YP_001492330.1 CDS A1E_03025 NC_009879.1 638415 639782 R COG1137 ABC-type (unclassified) transport system, ATPase component; hypothetical protein complement(638415..639782) Rickettsia canadensis str. McKiel 5626546 YP_001492331.1 CDS A1E_03030 NC_009879.1 640132 640416 R COG1038 Pyruvate carboxylase; hypothetical protein complement(640132..640416) Rickettsia canadensis str. McKiel 5626547 YP_001492332.1 CDS A1E_03035 NC_009879.1 640424 642409 R COG0210 Superfamily I DNA and RNA helicases; DNA helicase II complement(640424..642409) Rickettsia canadensis str. McKiel 5626548 YP_001492333.1 CDS A1E_03040 NC_009879.1 642510 643355 R glycosyltransferase complement(642510..643355) Rickettsia canadensis str. McKiel 5626549 YP_001492334.1 CDS A1E_03045 NC_009879.1 643345 643698 R COG0463 Glycosyltransferases involved in cell wall biogenesis; hypothetical protein complement(643345..643698) Rickettsia canadensis str. McKiel 5626550 YP_001492335.1 CDS A1E_03065 NC_009879.1 644567 644728 D COG1012 NAD-dependent aldehyde dehydrogenases; hypothetical protein 644567..644728 Rickettsia canadensis str. McKiel 5626029 YP_001492336.1 CDS A1E_03080 NC_009879.1 646151 646369 R COG1943 Transposase and inactivated derivatives; transposase IS200-family protein complement(646151..646369) Rickettsia canadensis str. McKiel 5626030 YP_001492337.1 CDS A1E_03085 NC_009879.1 646284 646484 R transposase IS200-family protein complement(646284..646484) Rickettsia canadensis str. McKiel 5626031 YP_001492338.1 CDS A1E_03090 NC_009879.1 646636 646773 R hypothetical protein complement(646636..646773) Rickettsia canadensis str. McKiel 5626032 YP_001492339.1 CDS A1E_03095 NC_009879.1 646973 647104 R COG1943 Transposase and inactivated derivatives; hypothetical protein complement(646973..647104) Rickettsia canadensis str. McKiel 5626033 YP_001492340.1 CDS A1E_03100 NC_009879.1 647384 648316 R COG0492 Thioredoxin reductase; thioredoxin reductase complement(647384..648316) Rickettsia canadensis str. McKiel 5626034 YP_001492341.1 CDS A1E_03105 NC_009879.1 648332 649219 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein complement(648332..649219) Rickettsia canadensis str. McKiel 5626427 YP_001492342.1 CDS A1E_03110 NC_009879.1 649277 650206 R permease complement(649277..650206) Rickettsia canadensis str. McKiel 5626428 YP_001492343.1 CDS A1E_03115 NC_009879.1 650523 650654 D hypothetical protein 650523..650654 Rickettsia canadensis str. McKiel 5626429 YP_001492344.1 CDS A1E_03120 NC_009879.1 651146 651343 D COG0679 Predicted permeases; hypothetical protein 651146..651343 Rickettsia canadensis str. McKiel 5626430 YP_001492345.1 CDS A1E_03125 NC_009879.1 651711 653396 R COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; threonine dehydratase complement(651711..653396) Rickettsia canadensis str. McKiel 5626431 YP_001492346.1 CDS ppnK NC_009879.1 653482 654249 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 653482..654249 Rickettsia canadensis str. McKiel 5626432 YP_001492347.1 CDS A1E_03135 NC_009879.1 654603 654791 D hypothetical protein 654603..654791 Rickettsia canadensis str. McKiel 5626701 YP_001492348.1 CDS A1E_03140 NC_009879.1 655103 655333 D hypothetical protein 655103..655333 Rickettsia canadensis str. McKiel 5626702 YP_001492349.1 CDS A1E_03145 NC_009879.1 655891 656028 D COG0061 Predicted sugar kinase; hypothetical protein 655891..656028 Rickettsia canadensis str. McKiel 5626703 YP_001492350.1 CDS recR NC_009879.1 656115 656714 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(656115..656714) Rickettsia canadensis str. McKiel 5626704 YP_001492351.1 CDS A1E_03155 NC_009879.1 656723 657241 R COG1714 Predicted membrane protein/domain; hypothetical protein complement(656723..657241) Rickettsia canadensis str. McKiel 5626705 YP_001492352.1 CDS A1E_03160 NC_009879.1 657479 657907 D COG1238 Predicted membrane protein; hypothetical protein 657479..657907 Rickettsia canadensis str. McKiel 5626706 YP_001492353.1 CDS rbfA NC_009879.1 657871 658305 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 657871..658305 Rickettsia canadensis str. McKiel 5626770 YP_001492354.1 CDS A1E_03170 NC_009879.1 658634 659269 D COG4395 Uncharacterized protein conserved in bacteria; hypothetical protein 658634..659269 Rickettsia canadensis str. McKiel 5626771 YP_001492355.1 CDS A1E_03175 NC_009879.1 659445 661484 D COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; acylamino-acid-releasing enzyme 659445..661484 Rickettsia canadensis str. McKiel 5626772 YP_001492356.1 CDS sucC NC_009879.1 661660 662820 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 661660..662820 Rickettsia canadensis str. McKiel 5626773 YP_001492357.1 CDS A1E_03185 NC_009879.1 663016 663894 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 663016..663894 Rickettsia canadensis str. McKiel 5626774 YP_001492358.1 CDS A1E_03190 NC_009879.1 664171 664239 R hypothetical protein complement(664171..664239) Rickettsia canadensis str. McKiel 5626775 YP_001492359.1 CDS A1E_03195 NC_009879.1 664232 664342 R COG0074 Succinyl-CoA synthetase, alpha subunit; hypothetical protein complement(664232..664342) Rickettsia canadensis str. McKiel 5626680 YP_001492360.1 CDS A1E_03200 NC_009879.1 664600 665400 R COG1651 Protein-disulfide isomerase; Thiol:disulfide interchange protein DsbA complement(664600..665400) Rickettsia canadensis str. McKiel 5626681 YP_001492361.1 CDS smpB NC_009879.1 665439 665897 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(665439..665897) Rickettsia canadensis str. McKiel 5626682 YP_001492362.1 CDS A1E_03210 NC_009879.1 665894 666778 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(665894..666778) Rickettsia canadensis str. McKiel 5626683 YP_001492363.1 CDS A1E_03215 NC_009879.1 666900 667772 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(666900..667772) Rickettsia canadensis str. McKiel 5626684 YP_001492364.1 CDS A1E_03220 NC_009879.1 668028 668708 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; petR protein 668028..668708 Rickettsia canadensis str. McKiel 5626685 YP_001492365.1 CDS A1E_03225 NC_009879.1 668740 670146 D osmolarity sensor protein EnvZ 668740..670146 Rickettsia canadensis str. McKiel 5626191 YP_001492366.1 CDS A1E_03230 NC_009879.1 670169 670849 D COG0020 Undecaprenyl pyrophosphate synthase; undecaprenyl pyrophosphate synthetase 670169..670849 Rickettsia canadensis str. McKiel 5626192 YP_001492367.1 CDS A1E_03235 NC_009879.1 670809 671498 D COG0575 CDP-diglyceride synthetase; phosphatidate cytidylyltransferase 670809..671498 Rickettsia canadensis str. McKiel 5626193 YP_001492368.1 CDS A1E_03240 NC_009879.1 671688 672023 D COG2919 Septum formation initiator; hypothetical protein 671688..672023 Rickettsia canadensis str. McKiel 5626194 YP_001492369.1 CDS A1E_03245 NC_009879.1 672122 672733 D COG0349 Ribonuclease D; ribonuclease D 672122..672733 Rickettsia canadensis str. McKiel 5626195 YP_001492370.1 CDS leuS NC_009879.1 673305 675809 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(673305..675809) Rickettsia canadensis str. McKiel 5626196 YP_001492371.1 CDS A1E_03255 NC_009879.1 675990 676493 R COG0495 Leucyl-tRNA synthetase; hypothetical protein complement(675990..676493) Rickettsia canadensis str. McKiel 5626782 YP_001492372.1 CDS A1E_03260 NC_009879.1 676625 677764 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(676625..677764) Rickettsia canadensis str. McKiel 5626783 YP_001492373.1 CDS pheT NC_009879.1 677769 680282 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(677769..680282) Rickettsia canadensis str. McKiel 5626784 YP_001492374.1 CDS pheS NC_009879.1 680279 681328 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(680279..681328) Rickettsia canadensis str. McKiel 5626785 YP_001492375.1 CDS A1E_03275 NC_009879.1 681364 682632 R COG0621 2-methylthioadenine synthetase; MiaB-like tRNA modifying enzyme complement(681364..682632) Rickettsia canadensis str. McKiel 5626786 YP_001492376.1 CDS dapF NC_009879.1 682625 683434 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(682625..683434) Rickettsia canadensis str. McKiel 5626787 YP_001492377.1 CDS A1E_03285 NC_009879.1 684072 684275 D hypothetical protein 684072..684275 Rickettsia canadensis str. McKiel 5625814 YP_001492379.1 CDS A1E_03295 NC_009879.1 684434 685597 D COG0438 Glycosyltransferase; capM protein 684434..685597 Rickettsia canadensis str. McKiel 5625816 YP_001492380.1 CDS A1E_03300 NC_009879.1 685668 685820 D RND efflux system, outer membrane protein 685668..685820 Rickettsia canadensis str. McKiel 5625817 YP_001492381.1 CDS A1E_03305 NC_009879.1 686575 687234 R COG1538 Outer membrane protein; hypothetical protein complement(686575..687234) Rickettsia canadensis str. McKiel 5625818 YP_001492382.1 CDS murG NC_009879.1 687564 688628 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase complement(687564..688628) Rickettsia canadensis str. McKiel 5625819 YP_001492383.1 CDS A1E_03315 NC_009879.1 688625 689764 R cell division protein FtsW complement(688625..689764) Rickettsia canadensis str. McKiel 5626486 YP_001492384.1 CDS A1E_03320 NC_009879.1 689956 690534 D hypothetical protein 689956..690534 Rickettsia canadensis str. McKiel 5626487 YP_001492385.1 CDS A1E_03325 NC_009879.1 690832 691035 D COG0772 Bacterial cell division membrane protein; hypothetical protein 690832..691035 Rickettsia canadensis str. McKiel 5626488 YP_001492386.1 CDS murD NC_009879.1 691042 692409 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(691042..692409) Rickettsia canadensis str. McKiel 5626489 YP_001492387.1 CDS A1E_03335 NC_009879.1 692556 692801 R COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; hypothetical protein complement(692556..692801) Rickettsia canadensis str. McKiel 5626490 YP_001492388.1 CDS lspA NC_009879.1 692822 693412 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(692822..693412) Rickettsia canadensis str. McKiel 5626491 YP_001492389.1 CDS A1E_03345 NC_009879.1 693708 695081 R COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein complement(693708..695081) Rickettsia canadensis str. McKiel 5625897 YP_001492390.1 CDS A1E_03350 NC_009879.1 695834 696625 D COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome c oxidase polypeptide II 695834..696625 Rickettsia canadensis str. McKiel 5625898 YP_001492391.1 CDS A1E_03355 NC_009879.1 696664 697047 D COG0110 Acetyltransferase (isoleucine patch superfamily); virginiamycin A acetyltransferase 696664..697047 Rickettsia canadensis str. McKiel 5625899 YP_001492392.1 CDS A1E_03360 NC_009879.1 697067 698665 D COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome c oxidase polypeptide I 697067..698665 Rickettsia canadensis str. McKiel 5625900 YP_001492393.1 CDS A1E_03365 NC_009879.1 698892 699629 D COG2071 Predicted glutamine amidotransferases; hypothetical protein 698892..699629 Rickettsia canadensis str. McKiel 5625901 YP_001492394.1 CDS A1E_03370 NC_009879.1 700089 702875 D COG2887 RecB family exonuclease; hypothetical protein 700089..702875 Rickettsia canadensis str. McKiel 5625902 YP_001492395.1 CDS A1E_03375 NC_009879.1 702858 703805 R microcin C7 self-immunity protein complement(702858..703805) Rickettsia canadensis str. McKiel 5625841 YP_001492396.1 CDS A1E_03380 NC_009879.1 704098 704253 R COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; hypothetical protein complement(704098..704253) Rickettsia canadensis str. McKiel 5625842 YP_001492397.1 CDS A1E_03385 NC_009879.1 705230 707185 R COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); soluble lytic murein transglycosylase precursor complement(705230..707185) Rickettsia canadensis str. McKiel 5625843 YP_001492398.1 CDS dut NC_009879.1 707337 707783 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(707337..707783) Rickettsia canadensis str. McKiel 5625844 YP_001492399.1 CDS A1E_03395 NC_009879.1 707786 708700 R COG0616 Periplasmic serine proteases (ClpP class); protease sohB complement(707786..708700) Rickettsia canadensis str. McKiel 5625845 YP_001492400.1 CDS A1E_03400 NC_009879.1 708700 709368 R COG0526 Thiol-disulfide isomerase and thioredoxins; Thiol:disulfide interchange protein TlpA complement(708700..709368) Rickettsia canadensis str. McKiel 5625846 YP_001492401.1 CDS A1E_03405 NC_009879.1 709630 710256 R COG3485 Protocatechuate 3,4-dioxygenase beta subunit; protocatechuate-3,4-dioxygenase, beta subunit complement(709630..710256) Rickettsia canadensis str. McKiel 5626454 YP_001492402.1 CDS A1E_03410 NC_009879.1 710397 711392 D hypothetical protein 710397..711392 Rickettsia canadensis str. McKiel 5626455 YP_001492403.1 CDS A1E_03415 NC_009879.1 711440 711613 R hypothetical protein complement(711440..711613) Rickettsia canadensis str. McKiel 5626456 YP_001492404.1 CDS A1E_03420 NC_009879.1 711696 712073 D COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; hypothetical protein 711696..712073 Rickettsia canadensis str. McKiel 5626457 YP_001492405.1 CDS A1E_03425 NC_009879.1 712082 712921 D COG0672 High-affinity Fe2+/Pb2+ permease; FTR1 family protein 712082..712921 Rickettsia canadensis str. McKiel 5626458 YP_001492406.1 CDS A1E_03430 NC_009879.1 712961 713503 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 712961..713503 Rickettsia canadensis str. McKiel 5626459 YP_001492407.1 CDS A1E_03435 NC_009879.1 713500 714279 D COG2823 Predicted periplasmic or secreted lipoprotein; hypothetical protein 713500..714279 Rickettsia canadensis str. McKiel 5626151 YP_001492408.1 CDS A1E_03440 NC_009879.1 714263 714949 D COG0797 Lipoproteins; rare lipoprotein A precursor 714263..714949 Rickettsia canadensis str. McKiel 5626152 YP_001492409.1 CDS A1E_03445 NC_009879.1 715076 715996 R COG1686 D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein DacF precursor complement(715076..715996) Rickettsia canadensis str. McKiel 5626153 YP_001492410.1 CDS A1E_03450 NC_009879.1 716153 717397 R COG0477 Permeases of the major facilitator superfamily; AmpG protein complement(716153..717397) Rickettsia canadensis str. McKiel 5626154 YP_001492411.1 CDS A1E_03455 NC_009879.1 717572 719335 R COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug resistance protein complement(717572..719335) Rickettsia canadensis str. McKiel 5626155 YP_001492412.1 CDS ruvB NC_009879.1 719328 720356 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(719328..720356) Rickettsia canadensis str. McKiel 5626156 YP_001492413.1 CDS A1E_03465 NC_009879.1 720946 721146 R hypothetical protein complement(720946..721146) Rickettsia canadensis str. McKiel 5626057 YP_001492414.1 CDS A1E_03470 NC_009879.1 721433 721723 R COG2255 Holliday junction resolvasome, helicase subunit; hypothetical protein complement(721433..721723) Rickettsia canadensis str. McKiel 5626058 YP_001492415.1 CDS ruvA NC_009879.1 721854 722468 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(721854..722468) Rickettsia canadensis str. McKiel 5626059 YP_001492416.1 CDS A1E_03480 NC_009879.1 722470 722718 R hypothetical protein complement(722470..722718) Rickettsia canadensis str. McKiel 5626060 YP_001492417.1 CDS A1E_03485 NC_009879.1 722957 723187 R COG0632 Holliday junction resolvasome, DNA-binding subunit; hypothetical protein complement(722957..723187) Rickettsia canadensis str. McKiel 5626061 YP_001492418.1 CDS A1E_03490 NC_009879.1 723366 723554 R COG3177 Uncharacterized conserved protein; hypothetical protein complement(723366..723554) Rickettsia canadensis str. McKiel 5626062 YP_001492419.1 CDS A1E_03495 NC_009879.1 723720 725036 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(723720..725036) Rickettsia canadensis str. McKiel 5626140 YP_001492420.1 CDS folE NC_009879.1 725127 725786 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(725127..725786) Rickettsia canadensis str. McKiel 5626141 YP_001492421.1 CDS A1E_03505 NC_009879.1 725919 726935 R hypothetical protein complement(725919..726935) Rickettsia canadensis str. McKiel 5626142 YP_001492422.1 CDS A1E_03510 NC_009879.1 727506 727622 R COG0302 GTP cyclohydrolase I; hypothetical protein complement(727506..727622) Rickettsia canadensis str. McKiel 5626143 YP_001492423.1 CDS A1E_03515 NC_009879.1 728159 728893 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 728159..728893 Rickettsia canadensis str. McKiel 5625977 YP_001492424.1 CDS A1E_03520 NC_009879.1 728871 729038 D COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; hypothetical protein 728871..729038 Rickettsia canadensis str. McKiel 5625978 YP_001492425.1 CDS A1E_03535 NC_009879.1 730770 732293 D COG3202 ATP/ADP translocase; ADP,ATP carrier protein 730770..732293 Rickettsia canadensis str. McKiel 5625979 YP_001492426.1 CDS A1E_03540 NC_009879.1 732388 733332 D Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 732388..733332 Rickettsia canadensis str. McKiel 5625980 YP_001492427.1 CDS A1E_03545 NC_009879.1 734040 734252 D hypothetical protein 734040..734252 Rickettsia canadensis str. McKiel 5626134 YP_001492428.1 CDS A1E_03550 NC_009879.1 734623 734865 D hypothetical protein 734623..734865 Rickettsia canadensis str. McKiel 5626135 YP_001492429.1 CDS A1E_03555 NC_009879.1 735025 735234 D hypothetical protein 735025..735234 Rickettsia canadensis str. McKiel 5626136 YP_001492430.1 CDS A1E_03560 NC_009879.1 735322 735426 D hypothetical protein 735322..735426 Rickettsia canadensis str. McKiel 5626137 YP_001492431.1 CDS A1E_03565 NC_009879.1 735444 735584 D hypothetical protein 735444..735584 Rickettsia canadensis str. McKiel 5626138 YP_001492432.1 CDS A1E_03570 NC_009879.1 735933 736106 D COG0039 Malate/lactate dehydrogenases; hypothetical protein 735933..736106 Rickettsia canadensis str. McKiel 5626139 YP_001492433.1 CDS A1E_03575 NC_009879.1 736140 737468 R proline/betaine transporter complement(736140..737468) Rickettsia canadensis str. McKiel 5626637 YP_001492434.1 CDS A1E_03580 NC_009879.1 737776 737868 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(737776..737868) Rickettsia canadensis str. McKiel 5626638 YP_001492435.1 CDS A1E_03585 NC_009879.1 738097 740397 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(738097..740397) Rickettsia canadensis str. McKiel 5626639 YP_001492436.1 CDS A1E_03590 NC_009879.1 740506 741447 R COG0679 Predicted permeases; permease complement(740506..741447) Rickettsia canadensis str. McKiel 5626640 YP_001492437.1 CDS lysK NC_009879.1 741514 743082 R class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase complement(741514..743082) Rickettsia canadensis str. McKiel 5626641 YP_001492438.1 CDS A1E_03600 NC_009879.1 743307 743825 D hypothetical protein 743307..743825 Rickettsia canadensis str. McKiel 5626642 YP_001492439.1 CDS A1E_03605 NC_009879.1 743932 744102 R ABC transporter permease protein complement(743932..744102) Rickettsia canadensis str. McKiel 5625960 YP_001492440.1 CDS A1E_03620 NC_009879.1 745759 746547 R COG3023 Negative regulator of beta-lactamase expression; hypothetical protein complement(745759..746547) Rickettsia canadensis str. McKiel 5625961 YP_001492441.1 CDS A1E_03625 NC_009879.1 746785 746979 R COG1396 Predicted transcriptional regulators; hypothetical protein complement(746785..746979) Rickettsia canadensis str. McKiel 5625962 YP_001492442.1 CDS lnt NC_009879.1 747157 748647 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(747157..748647) Rickettsia canadensis str. McKiel 5625963 YP_001492443.1 CDS A1E_03635 NC_009879.1 748738 749520 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 748738..749520 Rickettsia canadensis str. McKiel 5625964 YP_001492444.1 CDS A1E_03640 NC_009879.1 749781 749915 R hypothetical protein complement(749781..749915) Rickettsia canadensis str. McKiel 5625965 YP_001492445.1 CDS A1E_03645 NC_009879.1 750599 750694 R hypothetical protein complement(750599..750694) Rickettsia canadensis str. McKiel 5625887 YP_001492446.1 CDS A1E_03650 NC_009879.1 750898 751812 R COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); hypothetical protein complement(750898..751812) Rickettsia canadensis str. McKiel 5625888 YP_001492447.1 CDS xerD NC_009879.1 751881 752807 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(751881..752807) Rickettsia canadensis str. McKiel 5625889 YP_001492448.1 CDS A1E_03660 NC_009879.1 754456 754929 D COG4765 Uncharacterized protein conserved in bacteria; hypothetical protein 754456..754929 Rickettsia canadensis str. McKiel 5625891 YP_001492449.1 CDS A1E_03665 NC_009879.1 754930 756177 D COG3307 Lipid A core - O-antigen ligase and related enzymes; hypothetical protein 754930..756177 Rickettsia canadensis str. McKiel 5626174 YP_001492450.1 CDS A1E_03670 NC_009879.1 756328 756699 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 756328..756699 Rickettsia canadensis str. McKiel 5626175 YP_001492451.1 CDS A1E_03675 NC_009879.1 756704 757228 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 756704..757228 Rickettsia canadensis str. McKiel 5626176 YP_001492452.1 CDS A1E_03680 NC_009879.1 757206 757796 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 757206..757796 Rickettsia canadensis str. McKiel 5626177 YP_001492453.1 CDS A1E_03685 NC_009879.1 757959 758084 D COG2827 Predicted endonuclease containing a URI domain; hypothetical protein 757959..758084 Rickettsia canadensis str. McKiel 5626178 YP_001492454.1 CDS A1E_03690 NC_009879.1 758161 759348 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 758161..759348 Rickettsia canadensis str. McKiel 5626179 YP_001492455.1 CDS A1E_03695 NC_009879.1 759367 759582 D COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; hypothetical protein 759367..759582 Rickettsia canadensis str. McKiel 5625903 YP_001492456.1 CDS A1E_03700 NC_009879.1 759697 760200 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 759697..760200 Rickettsia canadensis str. McKiel 5625904 YP_001492457.1 CDS A1E_03705 NC_009879.1 760193 760459 D COG0759 Uncharacterized conserved protein; hypothetical protein 760193..760459 Rickettsia canadensis str. McKiel 5625905 YP_001492458.1 CDS A1E_03710 NC_009879.1 760593 761135 D responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 760593..761135 Rickettsia canadensis str. McKiel 5625906 YP_001492459.1 CDS A1E_03715 NC_009879.1 762035 762277 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(762035..762277) Rickettsia canadensis str. McKiel 5625907 YP_001492460.1 CDS A1E_03720 NC_009879.1 762292 764922 R COG1722 Exonuclease VII small subunit; hypothetical protein complement(762292..764922) Rickettsia canadensis str. McKiel 5625908 YP_001492461.1 CDS rimM NC_009879.1 764991 765488 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 764991..765488 Rickettsia canadensis str. McKiel 5626501 YP_001492462.1 CDS A1E_03740 NC_009879.1 768727 768822 R hypothetical protein complement(768727..768822) Rickettsia canadensis str. McKiel 5626502 YP_001492463.1 CDS A1E_03745 NC_009879.1 769342 769527 D hypothetical protein 769342..769527 Rickettsia canadensis str. McKiel 5626503 YP_001492464.1 CDS A1E_03750 NC_009879.1 769712 770056 R COG0806 RimM protein, required for 16S rRNA processing; hypothetical protein complement(769712..770056) Rickettsia canadensis str. McKiel 5626504 YP_001492465.1 CDS A1E_03755 NC_009879.1 770730 771653 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(770730..771653) Rickettsia canadensis str. McKiel 5626505 YP_001492466.1 CDS rpsD NC_009879.1 771771 772388 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 771771..772388 Rickettsia canadensis str. McKiel 5626506 YP_001492467.1 CDS A1E_03765 NC_009879.1 772712 773890 R COG0438 Glycosyltransferase; glycosyltransferase complement(772712..773890) Rickettsia canadensis str. McKiel 5625992 YP_001492468.1 CDS A1E_03770 NC_009879.1 774024 774683 D hydrolase or acyltransferase 774024..774683 Rickettsia canadensis str. McKiel 5625993 YP_001492469.1 CDS A1E_03775 NC_009879.1 774911 775675 D COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 774911..775675 Rickettsia canadensis str. McKiel 5625994 YP_001492470.1 CDS A1E_03780 NC_009879.1 775680 776816 D COG0845 Membrane-fusion protein; RND family efflux transporter MFP subunit 775680..776816 Rickettsia canadensis str. McKiel 5625995 YP_001492471.1 CDS A1E_03785 NC_009879.1 776818 777858 R COG0438 Glycosyltransferase; hypothetical protein complement(776818..777858) Rickettsia canadensis str. McKiel 5625996 YP_001492472.1 CDS A1E_03790 NC_009879.1 777828 778796 R COG0463 Glycosyltransferases involved in cell wall biogenesis; minor teichoic acids biosynthesis protein ggab (ggab) complement(777828..778796) Rickettsia canadensis str. McKiel 5625997 YP_001492473.1 CDS A1E_03795 NC_009879.1 778797 779996 R COG0438 Glycosyltransferase; glycosyltransferase complement(778797..779996) Rickettsia canadensis str. McKiel 5626306 YP_001492474.1 CDS A1E_03800 NC_009879.1 779993 781216 R COG0438 Glycosyltransferase; glycosyltransferase complement(779993..781216) Rickettsia canadensis str. McKiel 5626307 YP_001492475.1 CDS A1E_03805 NC_009879.1 781249 782391 R COG0500 SAM-dependent methyltransferases; hypothetical protein complement(781249..782391) Rickettsia canadensis str. McKiel 5626308 YP_001492476.1 CDS A1E_03810 NC_009879.1 782388 783518 R COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase complement(782388..783518) Rickettsia canadensis str. McKiel 5626309 YP_001492477.1 CDS A1E_03815 NC_009879.1 783511 784536 R COG1086 Predicted nucleoside-diphosphate sugar epimerases; capD protein complement(783511..784536) Rickettsia canadensis str. McKiel 5626310 YP_001492478.1 CDS A1E_03820 NC_009879.1 784746 785600 R putative dTDP-4-dehydrorhamnose reductase complement(784746..785600) Rickettsia canadensis str. McKiel 5626311 YP_001492479.1 CDS A1E_03825 NC_009879.1 785686 785820 D COG1091 dTDP-4-dehydrorhamnose reductase; hypothetical protein 785686..785820 Rickettsia canadensis str. McKiel 5626612 YP_001492480.1 CDS A1E_03830 NC_009879.1 786157 786621 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(786157..786621) Rickettsia canadensis str. McKiel 5626613 YP_001492481.1 CDS A1E_03835 NC_009879.1 786620 788224 D hypothetical protein 786620..788224 Rickettsia canadensis str. McKiel 5626614 YP_001492482.1 CDS A1E_03840 NC_009879.1 788315 788419 D COG2194 Predicted membrane-associated, metal-dependent hydrolase; hypothetical protein 788315..788419 Rickettsia canadensis str. McKiel 5626615 YP_001492483.1 CDS A1E_03845 NC_009879.1 788594 789529 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 788594..789529 Rickettsia canadensis str. McKiel 5626616 YP_001492484.1 CDS A1E_03850 NC_009879.1 789611 790213 D COG0450 Peroxiredoxin; thioredoxin peroxidase 1 789611..790213 Rickettsia canadensis str. McKiel 5626617 YP_001492485.1 CDS A1E_03865 NC_009879.1 791189 793522 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 791189..793522 Rickettsia canadensis str. McKiel 5626063 YP_001492486.1 CDS gltX NC_009879.1 793687 795024 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 793687..795024 Rickettsia canadensis str. McKiel 5626064 YP_001492487.1 CDS A1E_03875 NC_009879.1 795318 795440 R hypothetical protein complement(795318..795440) Rickettsia canadensis str. McKiel 5626065 YP_001492488.1 CDS A1E_03880 NC_009879.1 795489 795788 R hypothetical protein complement(795489..795788) Rickettsia canadensis str. McKiel 5626066 YP_001492489.1 CDS A1E_03885 NC_009879.1 796213 796347 R hypothetical protein complement(796213..796347) Rickettsia canadensis str. McKiel 5626067 YP_001492490.1 CDS A1E_03890 NC_009879.1 796669 796899 R COG0008 Glutamyl- and glutaminyl-tRNA synthetases; hypothetical protein complement(796669..796899) Rickettsia canadensis str. McKiel 5626068 YP_001492491.1 CDS cyaY NC_009879.1 797625 797960 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(797625..797960) Rickettsia canadensis str. McKiel 5626401 YP_001492492.1 CDS A1E_03900 NC_009879.1 797957 798964 R hypothetical protein complement(797957..798964) Rickettsia canadensis str. McKiel 5626402 YP_001492493.1 CDS A1E_03905 NC_009879.1 799276 799575 D COG1559 Predicted periplasmic solute-binding protein; hypothetical protein 799276..799575 Rickettsia canadensis str. McKiel 5626403 YP_001492494.1 CDS lpxB NC_009879.1 799559 800716 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(799559..800716) Rickettsia canadensis str. McKiel 5626404 YP_001492495.1 CDS ppnK NC_009879.1 800747 800881 R inorganic polyphosphate/ATP-NAD kinase complement(800747..800881) Rickettsia canadensis str. McKiel 5626405 YP_001492496.1 CDS A1E_03920 NC_009879.1 801104 801256 R hypothetical protein complement(801104..801256) Rickettsia canadensis str. McKiel 5626406 YP_001492497.1 CDS A1E_03925 NC_009879.1 801321 801467 R hypothetical protein complement(801321..801467) Rickettsia canadensis str. McKiel 5626233 YP_001492498.1 CDS A1E_03930 NC_009879.1 801861 802160 R hypothetical protein complement(801861..802160) Rickettsia canadensis str. McKiel 5626234 YP_001492499.1 CDS A1E_03935 NC_009879.1 802289 802396 R hypothetical protein complement(802289..802396) Rickettsia canadensis str. McKiel 5626235 YP_001492500.1 CDS hslU NC_009879.1 802834 804186 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(802834..804186) Rickettsia canadensis str. McKiel 5626236 YP_001492501.1 CDS A1E_03945 NC_009879.1 804183 804731 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(804183..804731) Rickettsia canadensis str. McKiel 5626237 YP_001492502.1 CDS A1E_03950 NC_009879.1 804897 805250 D hypothetical protein 804897..805250 Rickettsia canadensis str. McKiel 5626238 YP_001492503.1 CDS A1E_03955 NC_009879.1 805449 805811 D hypothetical protein 805449..805811 Rickettsia canadensis str. McKiel 5626470 YP_001492504.1 CDS A1E_03960 NC_009879.1 805804 806820 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 805804..806820 Rickettsia canadensis str. McKiel 5626471 YP_001492505.1 CDS A1E_03965 NC_009879.1 806834 808594 D hypothetical protein 806834..808594 Rickettsia canadensis str. McKiel 5626472 YP_001492506.1 CDS A1E_03970 NC_009879.1 808721 810256 D hypothetical protein 808721..810256 Rickettsia canadensis str. McKiel 5626473 YP_001492507.1 CDS A1E_03975 NC_009879.1 810394 811710 D hypothetical protein 810394..811710 Rickettsia canadensis str. McKiel 5626474 YP_001492508.1 CDS A1E_03980 NC_009879.1 811661 812368 R hypothetical protein complement(811661..812368) Rickettsia canadensis str. McKiel 5626475 YP_001492509.1 CDS A1E_03985 NC_009879.1 813309 814259 R hypothetical protein complement(813309..814259) Rickettsia canadensis str. McKiel 5626185 YP_001492510.1 CDS A1E_03990 NC_009879.1 814249 814680 R hypothetical protein complement(814249..814680) Rickettsia canadensis str. McKiel 5626186 YP_001492511.1 CDS A1E_03995 NC_009879.1 814680 815408 R hypothetical protein complement(814680..815408) Rickettsia canadensis str. McKiel 5626187 YP_001492512.1 CDS A1E_04000 NC_009879.1 816919 817065 D hypothetical protein 816919..817065 Rickettsia canadensis str. McKiel 5626188 YP_001492513.1 CDS A1E_04005 NC_009879.1 817414 817629 D hypothetical protein 817414..817629 Rickettsia canadensis str. McKiel 5626189 YP_001492514.1 CDS hisS NC_009879.1 817943 819190 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(817943..819190) Rickettsia canadensis str. McKiel 5626190 YP_001492515.1 CDS A1E_04015 NC_009879.1 819353 820753 R hypothetical protein complement(819353..820753) Rickettsia canadensis str. McKiel 5625933 YP_001492516.1 CDS mnmA NC_009879.1 820897 822003 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(820897..822003) Rickettsia canadensis str. McKiel 5625934 YP_001492517.1 CDS A1E_04025 NC_009879.1 822218 823201 D hypothetical protein 822218..823201 Rickettsia canadensis str. McKiel 5625935 YP_001492518.1 CDS A1E_04030 NC_009879.1 823607 823792 R hypothetical protein complement(823607..823792) Rickettsia canadensis str. McKiel 5625936 YP_001492519.1 CDS A1E_04035 NC_009879.1 824329 824454 R hypothetical protein complement(824329..824454) Rickettsia canadensis str. McKiel 5625937 YP_001492520.1 CDS A1E_04040 NC_009879.1 824496 824714 R hypothetical protein complement(824496..824714) Rickettsia canadensis str. McKiel 5625938 YP_001492521.1 CDS A1E_04045 NC_009879.1 825596 826144 R involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein complement(825596..826144) Rickettsia canadensis str. McKiel 5626157 YP_001492522.1 CDS A1E_04050 NC_009879.1 826234 827124 D binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 826234..827124 Rickettsia canadensis str. McKiel 5626158 YP_001492523.1 CDS tolB NC_009879.1 827250 828584 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(827250..828584) Rickettsia canadensis str. McKiel 5626159 YP_001492524.1 CDS thyX NC_009879.1 828769 829659 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(828769..829659) Rickettsia canadensis str. McKiel 5626160 YP_001492525.1 CDS A1E_04065 NC_009879.1 830244 830372 R hypothetical protein complement(830244..830372) Rickettsia canadensis str. McKiel 5626161 YP_001492526.1 CDS A1E_04070 NC_009879.1 830528 831187 R hypothetical protein complement(830528..831187) Rickettsia canadensis str. McKiel 5626162 YP_001492527.1 CDS A1E_04075 NC_009879.1 831426 831554 D hypothetical protein 831426..831554 Rickettsia canadensis str. McKiel 5625971 YP_001492528.1 CDS A1E_04080 NC_009879.1 832040 832246 R hypothetical protein complement(832040..832246) Rickettsia canadensis str. McKiel 5625972 YP_001492529.1 CDS A1E_04085 NC_009879.1 832412 835087 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 832412..835087 Rickettsia canadensis str. McKiel 5625973 YP_001492530.1 CDS A1E_04090 NC_009879.1 835227 836006 R hypothetical protein complement(835227..836006) Rickettsia canadensis str. McKiel 5625974 YP_001492531.1 CDS A1E_04095 NC_009879.1 836008 836808 R hypothetical protein complement(836008..836808) Rickettsia canadensis str. McKiel 5625975 YP_001492532.1 CDS A1E_04100 NC_009879.1 836945 837859 R hypothetical protein complement(836945..837859) Rickettsia canadensis str. McKiel 5625976 YP_001492533.1 CDS A1E_04105 NC_009879.1 838206 838424 D hypothetical protein 838206..838424 Rickettsia canadensis str. McKiel 5625820 YP_001492534.1 CDS A1E_04110 NC_009879.1 840013 840180 R hypothetical protein complement(840013..840180) Rickettsia canadensis str. McKiel 5625821 YP_001492535.1 CDS A1E_04120 NC_009879.1 841156 841311 R hypothetical protein complement(841156..841311) Rickettsia canadensis str. McKiel 5625822 YP_001492536.1 CDS A1E_04125 NC_009879.1 841693 841881 R hypothetical protein complement(841693..841881) Rickettsia canadensis str. McKiel 5625823 YP_001492537.1 CDS A1E_04130 NC_009879.1 842599 842769 R hypothetical protein complement(842599..842769) Rickettsia canadensis str. McKiel 5625824 YP_001492538.1 CDS A1E_04135 NC_009879.1 842858 842956 R hypothetical protein complement(842858..842956) Rickettsia canadensis str. McKiel 5625825 YP_001492539.1 CDS A1E_04140 NC_009879.1 843134 843499 R hypothetical protein complement(843134..843499) Rickettsia canadensis str. McKiel 5626348 YP_001492540.1 CDS A1E_04150 NC_009879.1 844507 844620 R hypothetical protein complement(844507..844620) Rickettsia canadensis str. McKiel 5626349 YP_001492541.1 CDS A1E_04155 NC_009879.1 845381 846793 R hypothetical protein complement(845381..846793) Rickettsia canadensis str. McKiel 5626350 YP_001492542.1 CDS A1E_04160 NC_009879.1 846803 848578 R type IV secretion system component VirD4 complement(846803..848578) Rickettsia canadensis str. McKiel 5626351 YP_001492543.1 CDS A1E_04165 NC_009879.1 848751 849755 R type IV secretion system ATPase VirB11 complement(848751..849755) Rickettsia canadensis str. McKiel 5626352 YP_001492544.1 CDS A1E_04170 NC_009879.1 849752 851200 R hypothetical protein complement(849752..851200) Rickettsia canadensis str. McKiel 5626353 YP_001492545.1 CDS A1E_04175 NC_009879.1 851337 851819 R hypothetical protein complement(851337..851819) Rickettsia canadensis str. McKiel 5626578 YP_001492546.1 CDS A1E_04180 NC_009879.1 851806 852534 R hypothetical protein complement(851806..852534) Rickettsia canadensis str. McKiel 5626579 YP_001492547.1 CDS A1E_04185 NC_009879.1 853281 853979 D hypothetical protein 853281..853979 Rickettsia canadensis str. McKiel 5626580 YP_001492548.1 CDS A1E_04190 NC_009879.1 853981 854733 D hypothetical protein 853981..854733 Rickettsia canadensis str. McKiel 5626581 YP_001492549.1 CDS A1E_04195 NC_009879.1 854736 855071 D subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 854736..855071 Rickettsia canadensis str. McKiel 5626582 YP_001492550.1 CDS A1E_04200 NC_009879.1 855204 856490 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 855204..856490 Rickettsia canadensis str. McKiel 5626583 YP_001492551.1 CDS A1E_04205 NC_009879.1 856821 857012 D COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; hypothetical protein 856821..857012 Rickettsia canadensis str. McKiel 5626269 YP_001492552.1 CDS A1E_04210 NC_009879.1 857205 858668 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 857205..858668 Rickettsia canadensis str. McKiel 5626270 YP_001492553.1 CDS A1E_04215 NC_009879.1 858731 858883 D COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; antitoxin of toxin-antitoxin system VapB 858731..858883 Rickettsia canadensis str. McKiel 5626271 YP_001492554.1 CDS A1E_04220 NC_009879.1 859012 859389 D COG1487 Predicted nucleic acid-binding protein, contains PIN domain; putative monovalent cation/H+ antiporter subunit D 859012..859389 Rickettsia canadensis str. McKiel 5626272 YP_001492555.1 CDS A1E_04225 NC_009879.1 859398 860918 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 859398..860918 Rickettsia canadensis str. McKiel 5626273 YP_001492556.1 CDS A1E_04230 NC_009879.1 860925 862979 D COG1770 Protease II; protease II 860925..862979 Rickettsia canadensis str. McKiel 5626274 YP_001492557.1 CDS A1E_04235 NC_009879.1 863165 864265 D COG0772 Bacterial cell division membrane protein; putative monovalent cation/H+ antiporter subunit D 863165..864265 Rickettsia canadensis str. McKiel 5626535 YP_001492558.1 CDS rpsT NC_009879.1 865044 865316 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(865044..865316) Rickettsia canadensis str. McKiel 5626537 YP_001492559.1 CDS rplQ NC_009879.1 865335 865745 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(865335..865745) Rickettsia canadensis str. McKiel 5626538 YP_001492560.1 CDS A1E_04250 NC_009879.1 865758 866780 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(865758..866780) Rickettsia canadensis str. McKiel 5626539 YP_001492561.1 CDS A1E_04255 NC_009879.1 866799 867182 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(866799..867182) Rickettsia canadensis str. McKiel 5625858 YP_001492562.1 CDS rpsM NC_009879.1 867206 867643 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(867206..867643) Rickettsia canadensis str. McKiel 5625859 YP_001492563.1 CDS adk NC_009879.1 867640 868278 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(867640..868278) Rickettsia canadensis str. McKiel 5625860 YP_001492564.1 CDS secY NC_009879.1 868294 869595 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(868294..869595) Rickettsia canadensis str. McKiel 5625861 YP_001492565.1 CDS rplO NC_009879.1 869599 870060 R late assembly protein; 50S ribosomal protein L15 complement(869599..870060) Rickettsia canadensis str. McKiel 5625862 YP_001492566.1 CDS rpmD NC_009879.1 870074 870265 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(870074..870265) Rickettsia canadensis str. McKiel 5625863 YP_001492567.1 CDS rpsE NC_009879.1 870300 870818 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(870300..870818) Rickettsia canadensis str. McKiel 5626776 YP_001492568.1 CDS rplR NC_009879.1 870836 871192 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(870836..871192) Rickettsia canadensis str. McKiel 5626777 YP_001492569.1 CDS rplF NC_009879.1 871208 871741 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(871208..871741) Rickettsia canadensis str. McKiel 5626778 YP_001492570.1 CDS rpsH NC_009879.1 871750 872148 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(871750..872148) Rickettsia canadensis str. McKiel 5626779 YP_001492571.1 CDS rpsN NC_009879.1 872168 872473 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(872168..872473) Rickettsia canadensis str. McKiel 5626780 YP_001492572.1 CDS rplE NC_009879.1 872484 873029 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(872484..873029) Rickettsia canadensis str. McKiel 5626781 YP_001492573.1 CDS rplX NC_009879.1 873029 873358 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(873029..873358) Rickettsia canadensis str. McKiel 5626023 YP_001492574.1 CDS rplN NC_009879.1 873359 873727 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(873359..873727) Rickettsia canadensis str. McKiel 5626024 YP_001492575.1 CDS rpsQ NC_009879.1 873800 874033 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(873800..874033) Rickettsia canadensis str. McKiel 5626025 YP_001492576.1 CDS rpmC NC_009879.1 874035 874250 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(874035..874250) Rickettsia canadensis str. McKiel 5626026 YP_001492577.1 CDS rplP NC_009879.1 874243 874653 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(874243..874653) Rickettsia canadensis str. McKiel 5626027 YP_001492578.1 CDS rpsC NC_009879.1 874668 875321 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(874668..875321) Rickettsia canadensis str. McKiel 5626028 YP_001492579.1 CDS rplV NC_009879.1 875323 875682 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(875323..875682) Rickettsia canadensis str. McKiel 5626222 YP_001492580.1 CDS rpsS NC_009879.1 875691 875969 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(875691..875969) Rickettsia canadensis str. McKiel 5626223 YP_001492581.1 CDS rplB NC_009879.1 875994 876815 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(875994..876815) Rickettsia canadensis str. McKiel 5626224 YP_001492582.1 CDS rplW NC_009879.1 876816 877112 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(876816..877112) Rickettsia canadensis str. McKiel 5626225 YP_001492583.1 CDS rplD NC_009879.1 877109 877732 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(877109..877732) Rickettsia canadensis str. McKiel 5626226 YP_001492584.1 CDS rplC NC_009879.1 877842 878489 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(877842..878489) Rickettsia canadensis str. McKiel 5626227 YP_001492585.1 CDS rpsJ NC_009879.1 878490 878807 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(878490..878807) Rickettsia canadensis str. McKiel 5626407 YP_001492586.1 CDS A1E_04380 NC_009879.1 878901 880085 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(878901..880085) Rickettsia canadensis str. McKiel 5626408 YP_001492587.1 CDS A1E_04385 NC_009879.1 880699 881418 D elongation factor Tu 880699..881418 Rickettsia canadensis str. McKiel 5626411 YP_001492588.1 CDS A1E_04390 NC_009879.1 881677 881778 D COG0566 rRNA methylases; hypothetical protein 881677..881778 Rickettsia canadensis str. McKiel 5626911 YP_001492589.1 CDS fumC NC_009879.1 882124 883515 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 882124..883515 Rickettsia canadensis str. McKiel 5626912 YP_001492590.1 CDS A1E_04400 NC_009879.1 883817 883996 D COG0114 Fumarase; hypothetical protein 883817..883996 Rickettsia canadensis str. McKiel 5626913 YP_001492591.1 CDS A1E_04405 NC_009879.1 884309 885667 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 884309..885667 Rickettsia canadensis str. McKiel 5626914 YP_001492592.1 CDS A1E_04410 NC_009879.1 886028 886174 D COG0206 Cell division GTPase; hypothetical protein 886028..886174 Rickettsia canadensis str. McKiel 5625909 YP_001492593.1 CDS A1E_04415 NC_009879.1 886353 886610 D COG4574 Serine protease inhibitor ecotin; ecotin precursor 886353..886610 Rickettsia canadensis str. McKiel 5625910 YP_001492594.1 CDS A1E_04420 NC_009879.1 886866 887435 R COG0694 Thioredoxin-like proteins and domains; NifU-like domain-containing protein complement(886866..887435) Rickettsia canadensis str. McKiel 5625911 YP_001492595.1 CDS A1E_04425 NC_009879.1 888741 889973 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase RhlE complement(888741..889973) Rickettsia canadensis str. McKiel 5625912 YP_001492596.1 CDS A1E_04430 NC_009879.1 890505 890717 R cold shock-like protein complement(890505..890717) Rickettsia canadensis str. McKiel 5625913 YP_001492597.1 CDS A1E_04435 NC_009879.1 891044 891175 R hypothetical protein complement(891044..891175) Rickettsia canadensis str. McKiel 5625914 YP_001492598.1 CDS A1E_04440 NC_009879.1 892826 892990 R cell division protein FtsZ complement(892826..892990) Rickettsia canadensis str. McKiel 5626386 YP_001492599.1 CDS A1E_04445 NC_009879.1 893142 893261 R hypothetical protein complement(893142..893261) Rickettsia canadensis str. McKiel 5626387 YP_001492600.1 CDS A1E_04450 NC_009879.1 893825 893917 D COG1278 Cold shock proteins; hypothetical protein 893825..893917 Rickettsia canadensis str. McKiel 5626388 YP_001492601.1 CDS ksgA NC_009879.1 893969 894781 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(893969..894781) Rickettsia canadensis str. McKiel 5626389 YP_001492602.1 CDS A1E_04460 NC_009879.1 894903 895790 R COG0760 Parvulin-like peptidyl-prolyl isomerase; hypothetical protein complement(894903..895790) Rickettsia canadensis str. McKiel 5626540 YP_001492603.1 CDS ksgA NC_009879.1 896064 898184 R COG1452 Organic solvent tolerance protein OstA; dimethyladenosine transferase complement(896064..898184) Rickettsia canadensis str. McKiel 5626541 YP_001492604.1 CDS xseA NC_009879.1 898509 899843 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 898509..899843 Rickettsia canadensis str. McKiel 5626542 YP_001492605.1 CDS A1E_04475 NC_009879.1 899951 900109 D COG1570 Exonuclease VII, large subunit; hypothetical protein 899951..900109 Rickettsia canadensis str. McKiel 5626543 YP_001492606.1 CDS xseA NC_009879.1 901389 902171 D COG0708 Exonuclease III; exodeoxyribonuclease VII large subunit 901389..902171 Rickettsia canadensis str. McKiel 5626544 YP_001492607.1 CDS engA NC_009879.1 902439 903782 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 902439..903782 Rickettsia canadensis str. McKiel 5626040 YP_001492608.1 CDS A1E_04490 NC_009879.1 904653 904784 R hypothetical protein complement(904653..904784) Rickettsia canadensis str. McKiel 5626041 YP_001492609.1 CDS A1E_04495 NC_009879.1 906035 906262 R hypothetical protein complement(906035..906262) Rickettsia canadensis str. McKiel 5626042 YP_001492610.1 CDS A1E_04500 NC_009879.1 906325 906486 R COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein complement(906325..906486) Rickettsia canadensis str. McKiel 5626043 YP_001492611.1 CDS engA NC_009879.1 907306 908736 R COG0661 Predicted unusual protein kinase; GTP-binding protein EngA complement(907306..908736) Rickettsia canadensis str. McKiel 5626044 YP_001492612.1 CDS ubiE NC_009879.1 908733 909479 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(908733..909479) Rickettsia canadensis str. McKiel 5626045 YP_001492613.1 CDS A1E_04515 NC_009879.1 909507 910328 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 909507..910328 Rickettsia canadensis str. McKiel 5626754 YP_001492614.1 CDS A1E_04520 NC_009879.1 910851 911045 D mannose-1-phosphate guanylyltransferase 910851..911045 Rickettsia canadensis str. McKiel 5626755 YP_001492615.1 CDS A1E_04525 NC_009879.1 912078 912311 D COG0266 Formamidopyrimidine-DNA glycosylase; hypothetical protein 912078..912311 Rickettsia canadensis str. McKiel 5626756 YP_001492616.1 CDS A1E_04530 NC_009879.1 913044 913259 R COG4553 Poly-beta-hydroxyalkanoate depolymerase; Poly-beta-hydroxyalkanoate depolymerase complement(913044..913259) Rickettsia canadensis str. McKiel 5626757 YP_001492617.1 CDS ubiE NC_009879.1 913776 914585 R COG0084 Mg-dependent DNase; ubiquinone/menaquinone biosynthesis methyltransferase complement(913776..914585) Rickettsia canadensis str. McKiel 5626758 YP_001492618.1 CDS A1E_04540 NC_009879.1 914713 916245 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(914713..916245) Rickettsia canadensis str. McKiel 5626759 YP_001492619.1 CDS tmk NC_009879.1 916242 916853 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(916242..916853) Rickettsia canadensis str. McKiel 5625847 YP_001492620.1 CDS tdk NC_009879.1 917161 918498 D COG0477 Permeases of the major facilitator superfamily; thymidylate kinase 917161..918498 Rickettsia canadensis str. McKiel 5625848 YP_001492621.1 CDS ubiA NC_009879.1 918495 919337 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase complement(918495..919337) Rickettsia canadensis str. McKiel 5625849 YP_001492622.1 CDS ubiA NC_009879.1 919418 919582 D COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; prenyltransferase 919418..919582 Rickettsia canadensis str. McKiel 5625850 YP_001492623.1 CDS valS NC_009879.1 920473 922914 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 920473..922914 Rickettsia canadensis str. McKiel 5625851 YP_001492624.1 CDS A1E_04570 NC_009879.1 923153 923239 D COG0525 Valyl-tRNA synthetase; hypothetical protein 923153..923239 Rickettsia canadensis str. McKiel 5625852 YP_001492625.1 CDS A1E_04575 NC_009879.1 923959 925164 R COG1373 Predicted ATPase (AAA+ superfamily); ATPase complement(923959..925164) Rickettsia canadensis str. McKiel 5625939 YP_001492626.1 CDS A1E_04580 NC_009879.1 925260 926546 D hypothetical protein 925260..926546 Rickettsia canadensis str. McKiel 5625940 YP_001492627.1 CDS A1E_04585 NC_009879.1 926683 926841 D Alpha-(1,3)-fucosyltransferase 926683..926841 Rickettsia canadensis str. McKiel 5625941 YP_001492628.1 CDS A1E_04590 NC_009879.1 927798 927899 D hypothetical protein 927798..927899 Rickettsia canadensis str. McKiel 5625942 YP_001492629.1 CDS valS NC_009879.1 927950 928159 R COG1322 Uncharacterized protein conserved in bacteria; valyl-tRNA synthetase complement(927950..928159) Rickettsia canadensis str. McKiel 5625943 YP_001492630.1 CDS clpX NC_009879.1 928260 929537 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(928260..929537) Rickettsia canadensis str. McKiel 5625944 YP_001492631.1 CDS A1E_04605 NC_009879.1 929667 930218 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-alanine acetyltransferase complement(929667..930218) Rickettsia canadensis str. McKiel 5626008 YP_001492632.1 CDS A1E_04610 NC_009879.1 930215 930898 R COG0603 Predicted PP-loop superfamily ATPase; trans-regulatory protein ExsB complement(930215..930898) Rickettsia canadensis str. McKiel 5626009 YP_001492633.1 CDS A1E_04615 NC_009879.1 931419 933161 D multidrug resistance protein 931419..933161 Rickettsia canadensis str. McKiel 5626011 YP_001492634.1 CDS A1E_04620 NC_009879.1 933404 933646 D COG1132 ABC-type multidrug transport system, ATPase and permease components; hypothetical protein 933404..933646 Rickettsia canadensis str. McKiel 5626012 YP_001492635.1 CDS A1E_04625 NC_009879.1 934085 934207 D bicyclomycin resistance protein 934085..934207 Rickettsia canadensis str. McKiel 5626855 YP_001492636.1 CDS A1E_04630 NC_009879.1 934662 934850 R hypothetical protein complement(934662..934850) Rickettsia canadensis str. McKiel 5626856 YP_001492637.1 CDS A1E_04635 NC_009879.1 934898 934999 D COG0477 Permeases of the major facilitator superfamily; hypothetical protein 934898..934999 Rickettsia canadensis str. McKiel 5626857 YP_001492638.1 CDS A1E_04640 NC_009879.1 934992 936239 D COG4591 ABC-type transport system, involved in lipoprotein release, permease component; hypothetical protein 934992..936239 Rickettsia canadensis str. McKiel 5626858 YP_001492639.1 CDS A1E_04645 NC_009879.1 936232 936897 D lipoprotein releasing system ATP-binding protein LolD 936232..936897 Rickettsia canadensis str. McKiel 5626859 YP_001492640.1 CDS A1E_04650 NC_009879.1 936953 938836 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; hypothetical protein 936953..938836 Rickettsia canadensis str. McKiel 5626860 YP_001492641.1 CDS A1E_04655 NC_009879.1 938943 940184 D COG4536 Putative Mg2+ and Co2+ transporter CorB; hypothetical protein 938943..940184 Rickettsia canadensis str. McKiel 5626524 YP_001492642.1 CDS A1E_04660 NC_009879.1 940177 942177 D cytochrome c-type biogenesis protein ccmF 940177..942177 Rickettsia canadensis str. McKiel 5626525 YP_001492643.1 CDS A1E_04665 NC_009879.1 942597 942725 R hypothetical protein complement(942597..942725) Rickettsia canadensis str. McKiel 5626526 YP_001492644.1 CDS A1E_04670 NC_009879.1 943101 943208 R COG1138 Cytochrome c biogenesis factor; hypothetical protein complement(943101..943208) Rickettsia canadensis str. McKiel 5626527 YP_001492645.1 CDS A1E_04675 NC_009879.1 943592 948505 R COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain; Outer membrane protein B complement(943592..948505) Rickettsia canadensis str. McKiel 5626528 YP_001492646.1 CDS A1E_04680 NC_009879.1 948876 949481 R COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein complement(948876..949481) Rickettsia canadensis str. McKiel 5626529 YP_001492647.1 CDS clpX NC_009879.1 949883 950827 R COG1472 Beta-glucosidase-related glycosidases; ATP-dependent protease ATP-binding subunit complement(949883..950827) Rickettsia canadensis str. McKiel 5626882 YP_001492648.1 CDS A1E_04690 NC_009879.1 951048 951929 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(951048..951929) Rickettsia canadensis str. McKiel 5626883 YP_001492649.1 CDS lpxK NC_009879.1 951892 952872 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(951892..952872) Rickettsia canadensis str. McKiel 5626884 YP_001492650.1 CDS A1E_04700 NC_009879.1 953054 953908 R COG0739 Membrane proteins related to metalloendopeptidases; periplasmic protein complement(953054..953908) Rickettsia canadensis str. McKiel 5626885 YP_001492651.1 CDS lpxK NC_009879.1 953872 954189 R tetraacyldisaccharide 4'-kinase complement(953872..954189) Rickettsia canadensis str. McKiel 5626886 YP_001492652.1 CDS A1E_04710 NC_009879.1 954527 954667 R COG2961 Protein involved in catabolism of external DNA; hypothetical protein complement(954527..954667) Rickettsia canadensis str. McKiel 5626887 YP_001492653.1 CDS ligA NC_009879.1 955287 957356 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(955287..957356) Rickettsia canadensis str. McKiel 5626117 YP_001492654.1 CDS ligA NC_009879.1 957373 959982 R COG4748 Uncharacterized conserved protein; NAD-dependent DNA ligase LigA complement(957373..959982) Rickettsia canadensis str. McKiel 5626118 YP_001492655.1 CDS tgt NC_009879.1 960095 961180 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(960095..961180) Rickettsia canadensis str. McKiel 5626119 YP_001492656.1 CDS A1E_04750 NC_009879.1 963392 963514 R COG0183 Acetyl-CoA acetyltransferase; Poly-beta-hydroxybutyrate polymerase complement(963392..963514) Rickettsia canadensis str. McKiel 5626120 YP_001492657.1 CDS A1E_04755 NC_009879.1 964081 965580 D COG3202 ATP/ADP translocase; ADP,ATP carrier protein 964081..965580 Rickettsia canadensis str. McKiel 5626121 YP_001492658.1 CDS A1E_04760 NC_009879.1 966034 966930 R COG1253 Hemolysins and related proteins containing CBS domains; acetyl-CoA acetyltransferase complement(966034..966930) Rickettsia canadensis str. McKiel 5626122 YP_001492659.1 CDS A1E_04765 NC_009879.1 966947 967465 R COG0319 Predicted metal-dependent hydrolase; putative metalloprotease complement(966947..967465) Rickettsia canadensis str. McKiel 5626572 YP_001492660.1 CDS A1E_04770 NC_009879.1 967655 968545 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(967655..968545) Rickettsia canadensis str. McKiel 5626573 YP_001492661.1 CDS glyA NC_009879.1 968538 969800 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(968538..969800) Rickettsia canadensis str. McKiel 5626574 YP_001492662.1 CDS A1E_04780 NC_009879.1 970011 970658 R COG0400 Predicted esterase; Serine esterase complement(970011..970658) Rickettsia canadensis str. McKiel 5626575 YP_001492663.1 CDS A1E_04785 NC_009879.1 970753 971067 R COG0278 Glutaredoxin-related protein; glutaredoxin-like protein grla complement(970753..971067) Rickettsia canadensis str. McKiel 5626576 YP_001492664.1 CDS A1E_04790 NC_009879.1 971283 971912 D COG0177 Predicted EndoIII-related endonuclease; endonuclease III 971283..971912 Rickettsia canadensis str. McKiel 5626577 YP_001492665.1 CDS A1E_04795 NC_009879.1 972127 972966 R COG0313 Predicted methyltransferases; hypothetical protein complement(972127..972966) Rickettsia canadensis str. McKiel 5625986 YP_001492666.1 CDS A1E_04800 NC_009879.1 972992 974110 D ABC-type transport systems periplasmic component 972992..974110 Rickettsia canadensis str. McKiel 5625987 YP_001492667.1 CDS tatA NC_009879.1 974312 974476 R TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A complement(974312..974476) Rickettsia canadensis str. McKiel 5625988 YP_001492668.1 CDS glyA NC_009879.1 974553 975149 D COG1267 Phosphatidylglycerophosphatase A and related proteins; serine hydroxymethyltransferase 974553..975149 Rickettsia canadensis str. McKiel 5625989 YP_001492669.1 CDS rplU NC_009879.1 975220 975537 D COG0261 Ribosomal protein L21; 50S ribosomal protein L21 975220..975537 Rickettsia canadensis str. McKiel 5625990 YP_001492670.1 CDS rpmA NC_009879.1 975562 975822 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 975562..975822 Rickettsia canadensis str. McKiel 5625991 YP_001492671.1 CDS A1E_04825 NC_009879.1 976119 977324 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 976119..977324 Rickettsia canadensis str. McKiel 5625787 YP_001492672.1 CDS A1E_04830 NC_009879.1 977627 978127 D COG0527 Aspartokinases; hypothetical protein 977627..978127 Rickettsia canadensis str. McKiel 5625788 YP_001492673.1 CDS A1E_04835 NC_009879.1 978418 979665 R proline/betaine transporter complement(978418..979665) Rickettsia canadensis str. McKiel 5625789 YP_001492674.1 CDS A1E_04840 NC_009879.1 980444 980581 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(980444..980581) Rickettsia canadensis str. McKiel 5625790 YP_001492675.1 CDS A1E_04845 NC_009879.1 980588 980944 R COG1426 Uncharacterized protein conserved in bacteria; hypothetical protein complement(980588..980944) Rickettsia canadensis str. McKiel 5625791 YP_001492676.1 CDS A1E_04850 NC_009879.1 980948 985702 R COG2902 NAD-specific glutamate dehydrogenase; aspartate kinase complement(980948..985702) Rickettsia canadensis str. McKiel 5625792 YP_001492677.1 CDS trmE NC_009879.1 985785 987122 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 985785..987122 Rickettsia canadensis str. McKiel 5626788 YP_001492678.1 CDS trmE NC_009879.1 987344 988708 D COG0486 Predicted GTPase; tRNA modification GTPase TrmE 987344..988708 Rickettsia canadensis str. McKiel 5626789 YP_001492679.1 CDS recA NC_009879.1 990368 991399 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 990368..991399 Rickettsia canadensis str. McKiel 5626790 YP_001492680.1 CDS fabG NC_009879.1 991392 992117 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 991392..992117 Rickettsia canadensis str. McKiel 5626791 YP_001492681.1 CDS acpP NC_009879.1 992277 992537 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 992277..992537 Rickettsia canadensis str. McKiel 5626792 YP_001492682.1 CDS A1E_04880 NC_009879.1 992574 993854 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 992574..993854 Rickettsia canadensis str. McKiel 5626793 YP_001492683.1 CDS A1E_04910 NC_009879.1 995726 996793 D hypothetical protein 995726..996793 Rickettsia canadensis str. McKiel 5626321 YP_001492684.1 CDS A1E_04915 NC_009879.1 996812 997048 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; 3-oxoacyl-(acyl carrier protein) synthase II 996812..997048 Rickettsia canadensis str. McKiel 5626322 YP_001492685.1 CDS gmk NC_009879.1 997578 998156 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(997578..998156) Rickettsia canadensis str. McKiel 5626323 YP_001492686.1 CDS A1E_04925 NC_009879.1 998167 998400 R COG1396 Predicted transcriptional regulators; hypothetical protein complement(998167..998400) Rickettsia canadensis str. McKiel 5626324 YP_001492687.1 CDS A1E_04930 NC_009879.1 998954 999793 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(998954..999793) Rickettsia canadensis str. McKiel 5626325 YP_001492688.1 CDS A1E_04935 NC_009879.1 999796 1000836 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(999796..1000836) Rickettsia canadensis str. McKiel 5626326 YP_001492689.1 CDS A1E_04940 NC_009879.1 1001019 1002020 R COG0795 Predicted permeases; hypothetical protein complement(1001019..1002020) Rickettsia canadensis str. McKiel 5626670 YP_001492690.1 CDS gmk NC_009879.1 1002581 1003048 R COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; guanylate kinase complement(1002581..1003048) Rickettsia canadensis str. McKiel 5626672 YP_001492691.1 CDS A1E_04950 NC_009879.1 1003389 1004342 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III complement(1003389..1004342) Rickettsia canadensis str. McKiel 5626673 YP_001492692.1 CDS rpmF NC_009879.1 1004355 1004555 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(1004355..1004555) Rickettsia canadensis str. McKiel 5626674 YP_001492693.1 CDS A1E_04960 NC_009879.1 1004658 1005131 D COG2913 Small protein A (tmRNA-binding); hypothetical protein 1004658..1005131 Rickettsia canadensis str. McKiel 5626263 YP_001492694.1 CDS rpmF NC_009879.1 1005296 1006207 D COG0552 Signal recognition particle GTPase; 50S ribosomal protein L32 1005296..1006207 Rickettsia canadensis str. McKiel 5626264 YP_001492695.1 CDS A1E_04970 NC_009879.1 1006343 1008970 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1006343..1008970 Rickettsia canadensis str. McKiel 5626265 YP_001492696.1 CDS dnaE NC_009879.1 1009212 1012814 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(1009212..1012814) Rickettsia canadensis str. McKiel 5626266 YP_001492697.1 CDS A1E_04980 NC_009879.1 1013016 1014335 R UDP-glucose 6-dehydrogenase complement(1013016..1014335) Rickettsia canadensis str. McKiel 5626267 YP_001492698.1 CDS A1E_04985 NC_009879.1 1014596 1017106 D COG1004 Predicted UDP-glucose 6-dehydrogenase; hypothetical protein 1014596..1017106 Rickettsia canadensis str. McKiel 5626268 YP_001492699.1 CDS A1E_04990 NC_009879.1 1017160 1018542 D COG0477 Permeases of the major facilitator superfamily; ampG protein 1017160..1018542 Rickettsia canadensis str. McKiel 5626805 YP_001492700.1 CDS dnaE NC_009879.1 1018601 1019356 D COG0805 Sec-independent protein secretion pathway component TatC; DNA polymerase III subunit alpha 1018601..1019356 Rickettsia canadensis str. McKiel 5626806 YP_001492701.1 CDS A1E_05000 NC_009879.1 1019334 1020611 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1019334..1020611 Rickettsia canadensis str. McKiel 5626807 YP_001492702.1 CDS A1E_05005 NC_009879.1 1020985 1023417 D Type IV secretion/conjugal transfer ATPase, VirB4 family protein 1020985..1023417 Rickettsia canadensis str. McKiel 5626808 YP_001492703.1 CDS A1E_05010 NC_009879.1 1023567 1027058 D COG3451 Type IV secretory pathway, VirB4 components; hypothetical protein 1023567..1027058 Rickettsia canadensis str. McKiel 5626809 YP_001492704.1 CDS A1E_05015 NC_009879.1 1027063 1027971 D tellurium resistance protein TerC 1027063..1027971 Rickettsia canadensis str. McKiel 5626810 YP_001492705.1 CDS A1E_05020 NC_009879.1 1028015 1028446 D hypothetical protein 1028015..1028446 Rickettsia canadensis str. McKiel 5626111 YP_001492706.1 CDS A1E_05025 NC_009879.1 1028660 1028737 D COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 1028660..1028737 Rickettsia canadensis str. McKiel 5626112 YP_001492707.1 CDS A1E_05030 NC_009879.1 1028886 1030550 D COG0500 SAM-dependent methyltransferases; seryl-tRNA synthetase 1028886..1030550 Rickettsia canadensis str. McKiel 5626113 YP_001492708.1 CDS A1E_05035 NC_009879.1 1030704 1031321 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1030704..1031321 Rickettsia canadensis str. McKiel 5626114 YP_001492709.1 CDS A1E_05040 NC_009879.1 1031314 1031628 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1031314..1031628 Rickettsia canadensis str. McKiel 5626115 YP_001492710.1 CDS A1E_05045 NC_009879.1 1031631 1033616 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1031631..1033616 Rickettsia canadensis str. McKiel 5626116 YP_001492711.1 CDS A1E_05050 NC_009879.1 1033753 1035234 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1033753..1035234 Rickettsia canadensis str. McKiel 5626606 YP_001492712.1 CDS A1E_05055 NC_009879.1 1035446 1036159 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1035446..1036159 Rickettsia canadensis str. McKiel 5626607 YP_001492713.1 CDS A1E_05060 NC_009879.1 1036156 1036293 R COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component; hypothetical protein complement(1036156..1036293) Rickettsia canadensis str. McKiel 5626608 YP_001492714.1 CDS A1E_05065 NC_009879.1 1036597 1036794 D COG1373 Predicted ATPase (AAA+ superfamily); NADH dehydrogenase subunit M 1036597..1036794 Rickettsia canadensis str. McKiel 5626609 YP_001492715.1 CDS A1E_05070 NC_009879.1 1037352 1037831 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(1037352..1037831) Rickettsia canadensis str. McKiel 5626610 YP_001492716.1 CDS A1E_05075 NC_009879.1 1037983 1038147 R COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); hypothetical protein complement(1037983..1038147) Rickettsia canadensis str. McKiel 5626611 YP_001492717.1 CDS A1E_05080 NC_009879.1 1038369 1039388 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(1038369..1039388) Rickettsia canadensis str. McKiel 5626822 YP_001492718.1 CDS A1E_05085 NC_009879.1 1039630 1041660 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(1039630..1041660) Rickettsia canadensis str. McKiel 5626823 YP_001492719.1 CDS A1E_05090 NC_009879.1 1041833 1042189 R COG3671 Predicted membrane protein; NADH dehydrogenase subunit G complement(1041833..1042189) Rickettsia canadensis str. McKiel 5626824 YP_001492720.1 CDS A1E_05095 NC_009879.1 1042559 1045192 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1042559..1045192) Rickettsia canadensis str. McKiel 5626825 YP_001492721.1 CDS atpC NC_009879.1 1045341 1045655 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1045341..1045655) Rickettsia canadensis str. McKiel 5626826 YP_001492722.1 CDS A1E_05105 NC_009879.1 1045748 1047169 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1045748..1047169) Rickettsia canadensis str. McKiel 5626827 YP_001492723.1 CDS A1E_05110 NC_009879.1 1047277 1048143 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1047277..1048143) Rickettsia canadensis str. McKiel 5626280 YP_001492724.1 CDS A1E_05115 NC_009879.1 1048251 1049789 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1048251..1049789) Rickettsia canadensis str. McKiel 5626281 YP_001492725.1 CDS A1E_05120 NC_009879.1 1049914 1050558 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1049914..1050558) Rickettsia canadensis str. McKiel 5626282 YP_001492726.1 CDS A1E_05125 NC_009879.1 1050621 1052009 R Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1050621..1052009) Rickettsia canadensis str. McKiel 5626283 YP_001492727.1 CDS A1E_05130 NC_009879.1 1052682 1052801 R COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; hypothetical protein complement(1052682..1052801) Rickettsia canadensis str. McKiel 5626284 YP_001492728.1 CDS A1E_05135 NC_009879.1 1053416 1055788 R COG5009 Membrane carboxypeptidase/penicillin-binding protein; 1A family penicillin-binding protein complement(1053416..1055788) Rickettsia canadensis str. McKiel 5626285 YP_001492729.1 CDS A1E_05140 NC_009879.1 1055957 1057297 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(1055957..1057297) Rickettsia canadensis str. McKiel 5626046 YP_001492730.1 CDS A1E_05145 NC_009879.1 1057658 1057840 R hypothetical protein complement(1057658..1057840) Rickettsia canadensis str. McKiel 5626047 YP_001492731.1 CDS A1E_05150 NC_009879.1 1057937 1058014 R hypothetical protein complement(1057937..1058014) Rickettsia canadensis str. McKiel 5626048 YP_001492732.1 CDS A1E_05155 NC_009879.1 1058486 1058809 D COG0621 2-methylthioadenine synthetase; hypothetical protein 1058486..1058809 Rickettsia canadensis str. McKiel 5626049 YP_001492733.1 CDS A1E_05160 NC_009879.1 1058809 1059030 D AAA family ATPase 1058809..1059030 Rickettsia canadensis str. McKiel 5626050 YP_001492734.1 CDS A1E_05165 NC_009879.1 1059845 1059946 R hypothetical protein complement(1059845..1059946) Rickettsia canadensis str. McKiel 5626051 YP_001492735.1 CDS A1E_05170 NC_009879.1 1059983 1060114 R COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein complement(1059983..1060114) Rickettsia canadensis str. McKiel 5625966 YP_001492736.1 CDS A1E_05175 NC_009879.1 1060217 1060696 R hypothetical protein complement(1060217..1060696) Rickettsia canadensis str. McKiel 5625967 YP_001492737.1 CDS A1E_05180 NC_009879.1 1060689 1062416 R COG0475 Kef-type K+ transport systems, membrane components; glutathione-regulated potassium-efflux system protein kefb (kefb) complement(1060689..1062416) Rickettsia canadensis str. McKiel 5625968 YP_001492738.1 CDS A1E_05185 NC_009879.1 1062413 1062739 R COG0799 Uncharacterized homolog of plant Iojap protein; Iojap-related protein complement(1062413..1062739) Rickettsia canadensis str. McKiel 5625969 YP_001492739.1 CDS A1E_05190 NC_009879.1 1062898 1063149 D hypothetical protein 1062898..1063149 Rickettsia canadensis str. McKiel 5625970 YP_001492740.1 CDS A1E_05195 NC_009879.1 1063487 1063675 R hypothetical protein complement(1063487..1063675) Rickettsia canadensis str. McKiel 5626369 YP_001492741.1 CDS A1E_05200 NC_009879.1 1063917 1064090 R hypothetical protein complement(1063917..1064090) Rickettsia canadensis str. McKiel 5626370 YP_001492742.1 CDS A1E_05205 NC_009879.1 1065107 1065220 R hypothetical protein complement(1065107..1065220) Rickettsia canadensis str. McKiel 5626371 YP_001492743.1 CDS A1E_05210 NC_009879.1 1066056 1066175 R hypothetical protein complement(1066056..1066175) Rickettsia canadensis str. McKiel 5626372 YP_001492744.1 CDS A1E_05215 NC_009879.1 1066175 1066288 R hypothetical protein complement(1066175..1066288) Rickettsia canadensis str. McKiel 5626373 YP_001492745.1 CDS A1E_05220 NC_009879.1 1066266 1066466 R cell surface antigen-like protein Sca13 complement(1066266..1066466) Rickettsia canadensis str. McKiel 5626374 YP_001492746.1 CDS A1E_05225 NC_009879.1 1067129 1067230 R hypothetical protein complement(1067129..1067230) Rickettsia canadensis str. McKiel 5625804 YP_001492747.1 CDS A1E_05230 NC_009879.1 1067331 1067519 R COG0271 Stress-induced morphogen (activity unknown); dihydrolipoamide dehydrogenase complement(1067331..1067519) Rickettsia canadensis str. McKiel 5625805 YP_001492748.1 CDS infA NC_009879.1 1069123 1069338 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1069123..1069338 Rickettsia canadensis str. McKiel 5625807 YP_001492749.1 CDS A1E_05240 NC_009879.1 1069351 1069959 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1069351..1069959 Rickettsia canadensis str. McKiel 5625808 YP_001492750.1 CDS A1E_05245 NC_009879.1 1070097 1070528 R COG1734 DnaK suppressor protein; Maf-like protein complement(1070097..1070528) Rickettsia canadensis str. McKiel 5625798 YP_001492751.1 CDS xerC NC_009879.1 1070634 1071551 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(1070634..1071551) Rickettsia canadensis str. McKiel 5625799 YP_001492752.1 CDS A1E_05255 NC_009879.1 1071874 1072476 R COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; phospholipase D (PLD) superfamily protein complement(1071874..1072476) Rickettsia canadensis str. McKiel 5625800 YP_001492753.1 CDS A1E_05260 NC_009879.1 1074399 1076027 R COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; UbiD family decarboxylase complement(1074399..1076027) Rickettsia canadensis str. McKiel 5625801 YP_001492754.1 CDS A1E_05265 NC_009879.1 1076229 1077803 R COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase complement(1076229..1077803) Rickettsia canadensis str. McKiel 5625802 YP_001492755.1 CDS A1E_05270 NC_009879.1 1078023 1084679 R COG3210 Large exoproteins involved in heme utilization or adhesion; 190-kDa cell surface antigen complement(1078023..1084679) Rickettsia canadensis str. McKiel 5625803 YP_001492756.1 CDS A1E_05275 NC_009879.1 1085152 1087386 R cell division protein FtsK-like protein complement(1085152..1087386) Rickettsia canadensis str. McKiel 5625869 YP_001492757.1 CDS A1E_05280 NC_009879.1 1087621 1087995 R hypothetical protein complement(1087621..1087995) Rickettsia canadensis str. McKiel 5625870 YP_001492758.1 CDS xerC NC_009879.1 1088089 1088355 R COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; site-specific tyrosine recombinase XerC complement(1088089..1088355) Rickettsia canadensis str. McKiel 5625871 YP_001492759.1 CDS A1E_05290 NC_009879.1 1088503 1089288 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1088503..1089288 Rickettsia canadensis str. McKiel 5625872 YP_001492760.1 CDS A1E_05295 NC_009879.1 1089786 1089911 D COG2003 DNA repair proteins; hypothetical protein 1089786..1089911 Rickettsia canadensis str. McKiel 5625873 YP_001492761.1 CDS A1E_05300 NC_009879.1 1090098 1091081 D undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1090098..1091081 Rickettsia canadensis str. McKiel 5625874 YP_001492762.1 CDS A1E_05305 NC_009879.1 1091078 1091395 D hypothetical protein 1091078..1091395 Rickettsia canadensis str. McKiel 5626089 YP_001492763.1 CDS A1E_05310 NC_009879.1 1091857 1091955 R COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; hypothetical protein complement(1091857..1091955) Rickettsia canadensis str. McKiel 5626090 YP_001492764.1 CDS A1E_05315 NC_009879.1 1092171 1092914 R COG3637 Opacity protein and related surface antigens; outer surface protein complement(1092171..1092914) Rickettsia canadensis str. McKiel 5626091 YP_001492765.1 CDS A1E_05320 NC_009879.1 1093171 1093845 R COG3637 Opacity protein and related surface antigens; putative outer surface protein complement(1093171..1093845) Rickettsia canadensis str. McKiel 5626092 YP_001492766.1 CDS A1E_05325 NC_009879.1 1094110 1094454 R COG1146 Ferredoxin; ferredoxin complement(1094110..1094454) Rickettsia canadensis str. McKiel 5626093 YP_001492767.1 CDS A1E_05330 NC_009879.1 1094459 1095148 R COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; Heme exporter protein C complement(1094459..1095148) Rickettsia canadensis str. McKiel 5626584 YP_001492768.1 CDS A1E_05335 NC_009879.1 1095208 1095810 R COG0590 Cytosine/adenosine deaminases; cytosine deaminase complement(1095208..1095810) Rickettsia canadensis str. McKiel 5626585 YP_001492769.1 CDS A1E_05340 NC_009879.1 1095791 1096696 R COG0053 Predicted Co/Zn/Cd cation transporters; cation diffusion facilitator family transporter complement(1095791..1096696) Rickettsia canadensis str. McKiel 5626586 YP_001492770.1 CDS A1E_05345 NC_009879.1 1096826 1097305 D COG4520 Surface antigen; 17 kDa surface antigen precursor 1096826..1097305 Rickettsia canadensis str. McKiel 5626587 YP_001492771.1 CDS A1E_05350 NC_009879.1 1097458 1097916 D COG1881 Phospholipid-binding protein; hypothetical protein 1097458..1097916 Rickettsia canadensis str. McKiel 5626588 YP_001492772.1 CDS A1E_05355 NC_009879.1 1097921 1098622 D COG1121 ABC-type Mn/Zn transport systems, ATPase component; methionine aminopeptidase 1097921..1098622 Rickettsia canadensis str. McKiel 5626589 YP_001492773.1 CDS uvrA NC_009879.1 1098625 1101486 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(1098625..1101486) Rickettsia canadensis str. McKiel 5626828 YP_001492774.1 CDS A1E_05365 NC_009879.1 1101595 1102053 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1101595..1102053 Rickettsia canadensis str. McKiel 5626829 YP_001492775.1 CDS A1E_05370 NC_009879.1 1102065 1102916 D COG0629 Single-stranded DNA-binding protein; single-strand DNA-binding protein 1102065..1102916 Rickettsia canadensis str. McKiel 5626830 YP_001492776.1 CDS A1E_05375 NC_009879.1 1103306 1103467 D COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1103306..1103467 Rickettsia canadensis str. McKiel 5626831 YP_001492777.1 CDS A1E_05380 NC_009879.1 1104065 1104382 D COG1872 Uncharacterized conserved protein; hypothetical protein 1104065..1104382 Rickettsia canadensis str. McKiel 5626833 YP_001492778.1 CDS A1E_05385 NC_009879.1 1104562 1106433 D molecular chaperone; heat shock protein 90 1104562..1106433 Rickettsia canadensis str. McKiel 5626686 YP_001492779.1 CDS A1E_05390 NC_009879.1 1106624 1107814 D catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 1106624..1107814 Rickettsia canadensis str. McKiel 5626687 YP_001492780.1 CDS tig NC_009879.1 1108110 1109438 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1108110..1109438 Rickettsia canadensis str. McKiel 5626688 YP_001492781.1 CDS obgE NC_009879.1 1109651 1110643 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1109651..1110643) Rickettsia canadensis str. McKiel 5626689 YP_001492782.1 CDS gltA NC_009879.1 1110978 1112288 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(1110978..1112288) Rickettsia canadensis str. McKiel 5626690 YP_001492783.1 CDS A1E_05410 NC_009879.1 1112613 1112792 R transcriptional regulator complement(1112613..1112792) Rickettsia canadensis str. McKiel 5626905 YP_001492784.1 CDS A1E_05415 NC_009879.1 1113243 1113311 R COG0372 Citrate synthase; hypothetical protein complement(1113243..1113311) Rickettsia canadensis str. McKiel 5626906 YP_001492785.1 CDS A1E_05420 NC_009879.1 1113589 1114377 R COG1573 Uracil-DNA glycosylase; N-terminus of bacteriophage-type DNA polymerase complement(1113589..1114377) Rickettsia canadensis str. McKiel 5626907 YP_001492786.1 CDS gltA NC_009879.1 1114394 1115371 D COG0564 Pseudouridylate synthases, 23S RNA-specific; type II citrate synthase 1114394..1115371 Rickettsia canadensis str. McKiel 5626908 YP_001492787.1 CDS A1E_05430 NC_009879.1 1115466 1116437 D COG2890 Methylase of polypeptide chain release factors; tRNA (guanine-N(7)-)-methyltransferase 1115466..1116437 Rickettsia canadensis str. McKiel 5626909 YP_001492788.1 CDS A1E_05435 NC_009879.1 1117010 1117948 R COG0009 Putative translation factor (SUA5); bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase complement(1117010..1117948) Rickettsia canadensis str. McKiel 5626910 YP_001492789.1 CDS glyS NC_009879.1 1118117 1120120 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1118117..1120120) Rickettsia canadensis str. McKiel 5626737 YP_001492790.1 CDS glyQ NC_009879.1 1120117 1120983 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1120117..1120983) Rickettsia canadensis str. McKiel 5626738 YP_001492791.1 CDS A1E_05450 NC_009879.1 1121151 1121780 R COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1121151..1121780) Rickettsia canadensis str. McKiel 5626739 YP_001492792.1 CDS A1E_05465 NC_009879.1 1122852 1122941 R hypothetical protein complement(1122852..1122941) Rickettsia canadensis str. McKiel 5626740 YP_001492793.1 CDS A1E_05470 NC_009879.1 1123125 1124078 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(1123125..1124078) Rickettsia canadensis str. McKiel 5626741 YP_001492794.1 CDS A1E_05475 NC_009879.1 1124087 1124599 R hypothetical protein complement(1124087..1124599) Rickettsia canadensis str. McKiel 5626742 YP_001492795.1 CDS glyQ NC_009879.1 1124889 1126460 R COG1474 Cdc6-related protein, AAA superfamily ATPase; glycyl-tRNA synthetase subunit alpha complement(1124889..1126460) Rickettsia canadensis str. McKiel 5625927 YP_001492796.1 CDS alaS NC_009879.1 1126618 1129254 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1126618..1129254 Rickettsia canadensis str. McKiel 5625928 YP_001492797.1 CDS truA NC_009879.1 1129475 1130212 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1129475..1130212) Rickettsia canadensis str. McKiel 5625929 YP_001492798.1 CDS A1E_05495 NC_009879.1 1130269 1132176 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(1130269..1132176) Rickettsia canadensis str. McKiel 5625930 YP_001492799.1 CDS dnaG NC_009879.1 1132350 1134134 R synthesizes RNA primers at the replication forks; DNA primase complement(1132350..1134134) Rickettsia canadensis str. McKiel 5625931 YP_001492800.1 CDS dnaG NC_009879.1 1134138 1134752 R COG0170 Dolichol kinase; DNA primase complement(1134138..1134752) Rickettsia canadensis str. McKiel 5625932 YP_001492801.1 CDS greA NC_009879.1 1135131 1135619 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1135131..1135619 Rickettsia canadensis str. McKiel 5626850 YP_001492802.1 CDS A1E_05515 NC_009879.1 1135914 1136195 R NAD(P) transhydrogenase subunit alpha complement(1135914..1136195) Rickettsia canadensis str. McKiel 5626851 YP_001492803.1 CDS A1E_05520 NC_009879.1 1136357 1136452 R COG3288 NAD/NADP transhydrogenase alpha subunit; hypothetical protein complement(1136357..1136452) Rickettsia canadensis str. McKiel 5626852 YP_001492804.1 CDS greA NC_009879.1 1137567 1138208 D COG2834 Outer membrane lipoprotein-sorting protein; transcription elongation factor GreA 1137567..1138208 Rickettsia canadensis str. McKiel 5626853 YP_001492805.1 CDS A1E_05545 NC_009879.1 1138528 1140162 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; rhe tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1138528..1140162 Rickettsia canadensis str. McKiel 5626854 YP_001492806.1 CDS A1E_05550 NC_009879.1 1140174 1140497 D COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 1140174..1140497 Rickettsia canadensis str. McKiel 5626888 YP_001492807.1 CDS A1E_05555 NC_009879.1 1140717 1141412 R COG3577 Predicted aspartyl protease; hypothetical protein complement(1140717..1141412) Rickettsia canadensis str. McKiel 5626889 YP_001492808.1 CDS A1E_05560 NC_009879.1 1141722 1142444 R COG1126 ABC-type polar amino acid transport system, ATPase component; glutamine ABC transporter ATP-binding protein complement(1141722..1142444) Rickettsia canadensis str. McKiel 5626890 YP_001492809.1 CDS A1E_05565 NC_009879.1 1142448 1143212 R COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; hypothetical protein complement(1142448..1143212) Rickettsia canadensis str. McKiel 5626891 YP_001492810.1 CDS A1E_05570 NC_009879.1 1143224 1143910 D COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 1143224..1143910 Rickettsia canadensis str. McKiel 5626892 YP_001492811.1 CDS A1E_05575 NC_009879.1 1144049 1145131 D COG0795 Predicted permeases; hypothetical protein 1144049..1145131 Rickettsia canadensis str. McKiel 5626893 YP_001492812.1 CDS A1E_05580 NC_009879.1 1145134 1145598 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(1145134..1145598) Rickettsia canadensis str. McKiel 5626228 YP_001492813.1 CDS A1E_05585 NC_009879.1 1145881 1147035 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(1145881..1147035) Rickettsia canadensis str. McKiel 5626230 YP_001492814.1 CDS A1E_05590 NC_009879.1 1147271 1147408 R hypothetical protein complement(1147271..1147408) Rickettsia canadensis str. McKiel 5626231 YP_001492815.1 CDS A1E_05595 NC_009879.1 1147439 1147501 R COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; hypothetical protein complement(1147439..1147501) Rickettsia canadensis str. McKiel 5626232 YP_001492816.1 CDS A1E_05600 NC_009879.1 1147614 1147733 R succinyl-diaminopimelate desuccinylase complement(1147614..1147733) Rickettsia canadensis str. McKiel 5626551 YP_001492817.1 CDS A1E_05605 NC_009879.1 1147753 1147878 R COG1434 Uncharacterized conserved protein; hypothetical protein complement(1147753..1147878) Rickettsia canadensis str. McKiel 5626552 YP_001492818.1 CDS lipB NC_009879.1 1148031 1148660 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1148031..1148660) Rickettsia canadensis str. McKiel 5626553 YP_001492819.1 CDS lipB NC_009879.1 1148662 1149408 R COG3023 Negative regulator of beta-lactamase expression; lipoyltransferase complement(1148662..1149408) Rickettsia canadensis str. McKiel 5626554 YP_001492820.1 CDS rpsP NC_009879.1 1149767 1150102 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1149767..1150102) Rickettsia canadensis str. McKiel 5626556 YP_001492821.1 CDS rpmG NC_009879.1 1150118 1150288 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1150118..1150288) Rickettsia canadensis str. McKiel 5626519 YP_001492822.1 CDS mutL NC_009879.1 1150384 1152216 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(1150384..1152216) Rickettsia canadensis str. McKiel 5626520 YP_001492823.1 CDS A1E_05635 NC_009879.1 1152213 1152377 R COG4391 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1152213..1152377) Rickettsia canadensis str. McKiel 5626521 YP_001492824.1 CDS A1E_05640 NC_009879.1 1152633 1153097 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 1152633..1153097 Rickettsia canadensis str. McKiel 5626522 YP_001492825.1 CDS A1E_05645 NC_009879.1 1153145 1153411 D oxidoreductase 1153145..1153411 Rickettsia canadensis str. McKiel 5626523 YP_001492826.1 CDS A1E_05650 NC_009879.1 1153952 1154263 D COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); hypothetical protein 1153952..1154263 Rickettsia canadensis str. McKiel 5626834 YP_001492827.1 CDS mutL NC_009879.1 1154505 1155770 D COG0477 Permeases of the major facilitator superfamily; DNA mismatch repair protein 1154505..1155770 Rickettsia canadensis str. McKiel 5626835 YP_001492828.1 CDS A1E_05660 NC_009879.1 1155914 1156747 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1155914..1156747 Rickettsia canadensis str. McKiel 5626836 YP_001492829.1 CDS A1E_05665 NC_009879.1 1156868 1157305 R COG1981 Predicted membrane protein; coproporphyrinogen III oxidase complement(1156868..1157305) Rickettsia canadensis str. McKiel 5626837 YP_001492830.1 CDS hemH NC_009879.1 1157317 1158360 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1157317..1158360) Rickettsia canadensis str. McKiel 5626838 YP_001492831.1 CDS hemE NC_009879.1 1158367 1159386 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(1158367..1159386) Rickettsia canadensis str. McKiel 5626839 A1E_t05682 tRNA A1E_t05682 NC_009879.1 8620 8695 R tRNA-Phe complement(8620..8695) Rickettsia canadensis str. McKiel 5626514 A1E_t05684 tRNA A1E_t05684 NC_009879.1 19274 19348 D tRNA-Glu 19274..19348 Rickettsia canadensis str. McKiel 5625867 A1E_t05686 tRNA A1E_t05686 NC_009879.1 87085 87159 D tRNA-Thr 87085..87159 Rickettsia canadensis str. McKiel 5626056 A1E_t05688 tRNA A1E_t05688 NC_009879.1 109832 109908 D tRNA-Met 109832..109908 Rickettsia canadensis str. McKiel 5626279 A1E_t05690 tRNA A1E_t05690 NC_009879.1 155537 155612 D tRNA-Trp 155537..155612 Rickettsia canadensis str. McKiel 5626295 A1E_t05692 tRNA A1E_t05692 NC_009879.1 185675 185750 R tRNA-Thr complement(185675..185750) Rickettsia canadensis str. McKiel 5626768 A1E_t05694 tRNA A1E_t05694 NC_009879.1 259101 259192 R tRNA-Ser complement(259101..259192) Rickettsia canadensis str. McKiel 5626564 A1E_t05696 tRNA A1E_t05696 NC_009879.1 307168 307244 D tRNA-Met 307168..307244 Rickettsia canadensis str. McKiel 5626328 A1E_t05698 tRNA A1E_t05698 NC_009879.1 353735 353809 D tRNA-Asn 353735..353809 Rickettsia canadensis str. McKiel 5626726 A1E_t05700 tRNA A1E_t05700 NC_009879.1 428567 428641 R tRNA-Gly complement(428567..428641) Rickettsia canadensis str. McKiel 5626340 A1E_t05702 tRNA A1E_t05702 NC_009879.1 433200 433286 R tRNA-Leu complement(433200..433286) Rickettsia canadensis str. McKiel 5626599 A1E_t05704 tRNA A1E_t05704 NC_009879.1 445181 445255 D tRNA-Ala 445181..445255 Rickettsia canadensis str. McKiel 5626071 A1E_t05706 tRNA A1E_t05706 NC_009879.1 475101 475177 R tRNA-Arg complement(475101..475177) Rickettsia canadensis str. McKiel 5626021 A1E_t05708 tRNA A1E_t05708 NC_009879.1 516449 516523 D tRNA-Gln 516449..516523 Rickettsia canadensis str. McKiel 5626424 A1E_t05710 tRNA A1E_t05710 NC_009879.1 516641 516717 R tRNA-Arg complement(516641..516717) Rickettsia canadensis str. McKiel 5626425 A1E_t05712 tRNA A1E_t05712 NC_009879.1 530508 530597 D tRNA-Ser 530508..530597 Rickettsia canadensis str. McKiel 5625984 A1E_t05714 tRNA A1E_t05714 NC_009879.1 547405 547492 D tRNA-Ser 547405..547492 Rickettsia canadensis str. McKiel 5626795 A1E_t05716 tRNA A1E_t05716 NC_009879.1 552374 552449 R tRNA-Ala complement(552374..552449) Rickettsia canadensis str. McKiel 5625885 A1E_t05718 tRNA A1E_t05718 NC_009879.1 556129 556205 D tRNA-Val 556129..556205 Rickettsia canadensis str. McKiel 5626499 A1E_t05720 tRNA A1E_t05720 NC_009879.1 632465 632541 D tRNA-Asp 632465..632541 Rickettsia canadensis str. McKiel 5626623 A1E_t05722 tRNA A1E_t05722 NC_009879.1 727737 727813 R tRNA-Ile complement(727737..727813) Rickettsia canadensis str. McKiel 5626144 A1E_t05724 tRNA A1E_t05724 NC_009879.1 727837 727912 R tRNA-Lys complement(727837..727912) Rickettsia canadensis str. McKiel 5626145 A1E_t05726 tRNA A1E_t05726 NC_009879.1 752829 752903 R tRNA-Cys complement(752829..752903) Rickettsia canadensis str. McKiel 5625890 A1E_t05728 tRNA A1E_t05728 NC_009879.1 864861 864936 R tRNA-Val complement(864861..864936) Rickettsia canadensis str. McKiel 5626536 A1E_t05730 tRNA A1E_t05730 NC_009879.1 880175 880248 R tRNA-Gly complement(880175..880248) Rickettsia canadensis str. McKiel 5626409 A1E_t05732 tRNA A1E_t05732 NC_009879.1 880419 880504 R tRNA-Tyr complement(880419..880504) Rickettsia canadensis str. McKiel 5626410 A1E_t05734 tRNA A1E_t05734 NC_009879.1 891284 891369 D tRNA-Leu 891284..891369 Rickettsia canadensis str. McKiel 5626385 A1E_t05736 tRNA A1E_t05736 NC_009879.1 931317 931393 D tRNA-His 931317..931393 Rickettsia canadensis str. McKiel 5626010 A1E_t05738 tRNA A1E_t05738 NC_009879.1 1002145 1002221 R tRNA-Met complement(1002145..1002221) Rickettsia canadensis str. McKiel 5626671 A1E_t05740 tRNA A1E_t05740 NC_009879.1 1069029 1069105 D tRNA-Pro 1069029..1069105 Rickettsia canadensis str. McKiel 5625806 A1E_t05742 tRNA A1E_t05742 NC_009879.1 1103896 1103972 R tRNA-Arg complement(1103896..1103972) Rickettsia canadensis str. McKiel 5626832 A1E_t05744 tRNA A1E_t05744 NC_009879.1 1145637 1145723 R tRNA-Leu complement(1145637..1145723) Rickettsia canadensis str. McKiel 5626229 A1E_t05746 tRNA A1E_t05746 NC_009879.1 1149518 1149592 R tRNA-Thr complement(1149518..1149592) Rickettsia canadensis str. McKiel 5626555 A1E_r01 rRNA A1E_r01 NC_009879.1 269229 272011 D 23S ribosomal RNA 269229..272011 Rickettsia canadensis str. McKiel 5696489 A1E_r05748 rRNA A1E_r05748 NC_009879.1 272249 272367 D 5S ribosomal RNA 272249..272367 Rickettsia canadensis str. McKiel 5626149 A1E_r05750 rRNA A1E_r05750 NC_009879.1 385940 387447 D 16S ribosomal RNA 385940..387447 Rickettsia canadensis str. McKiel 5626818