;	Biomipsmax funcat version 06.12.2001
01	METABOLISM
01.01	amino acid metabolism
01.01.01	amino acid biosynthesis
01.01.01.01	assimilation of ammonia, biosynthesis of the glutamate group
01.01.01.01.01	assimilation of ammonia
01.01.01.01.02	biosynthesis of the glutamate group (proline, hydroxyprolin, arginine, glutamine, glutamate)
01.01.01.01.02.01	biosynthesis of proline
01.01.01.01.02.02	biosynthesis of hydroxyproline
01.01.01.01.02.03	biosynthesis of arginine
01.01.01.01.02.04	biosynthesis of glutamine
01.01.01.01.02.05	biosynthesis of glutamate
01.01.01.03	urea cycle, biosynthesis of polyamines and creatine
01.01.01.03.01	urea cycle
01.01.01.03.02	biosynthesis of polyamines
01.01.01.03.03	biosynthesis of creatine
01.01.01.07	biosynthesis of the aspartate family
01.01.01.07.01	biosynthesis of aspartate
01.01.01.07.02	biosynthesis of asparagine
01.01.01.07.03	biosynthesis of threonine
01.01.01.07.04	biosynthesis of methionine
01.01.01.07.06	biosynthesis of lysine
01.01.01.07.06.01	diaminopimelin acid pathway
01.01.01.07.06.03	aminoadipic acid pathway
01.01.01.11	biosynthesis of the cysteine-aromatic group
01.01.01.11.01	biosynthesis of serine
01.01.01.11.03	biosynthesis of cysteine
01.01.01.11.05	biosynthesis of homocysteine
01.01.01.11.07	biosynthesis of glycine
01.01.01.11.09	biosynthesis of phenylalanine
01.01.01.11.11	biosynthesis of tyrosine
01.01.01.11.13	biosynthesis of tryptophan
01.01.01.11.15	biosynthesis of histidine
01.01.01.15	biosynthesis of the pyruvate family (alanine, isoleucine, leucine, valine) and D-alanine
01.01.01.15.01	biosynthesis of alanine
01.01.01.15.02	biosynthesis of isoleucine
01.01.01.15.03	biosynthesis of leucine
01.01.01.15.04	biosynthesis of valine
01.01.01.15.05	biosynthesis of D-alanine
01.01.04	regulation of amino acid metabolism
01.01.07	amino acid transport
01.01.10	amino acid degradation (catabolism)
01.01.10.01	degradation of amino acids of the glutamate group
01.01.10.01.01	degradation of proline
01.01.10.01.02	degradation of hydroxyproline
01.01.10.01.03	degradation of arginine
01.01.10.01.04	degradation of glutamate
01.01.10.01.05	degradation of glutamine
01.01.10.03	degradation of amino acids of the aspartate group
01.01.10.03.01	degradation of aspartate
01.01.10.03.02	degradation of asparagine
01.01.10.03.03	degradation of threonine
01.01.10.03.04	degradation of methionine
01.01.10.03.05	degradation of lysine
01.01.10.04	degradation of amino acids of the pyruvate family
01.01.10.04.01	degradation of alanine
01.01.10.04.02	degradation of valine
01.01.10.04.03	degradation of leucine
01.01.10.04.04	degradation of isoleucine
01.01.10.05	degradation of amino acids of the cysteine-aromatic group
01.01.10.05.01	degradation of serine
01.01.10.05.02	degradation of cysteine
01.01.10.05.03	degradation of homocysteine
01.01.10.05.04	degradation of glycine
01.01.10.05.05	degradation of phenylalanine
01.01.10.05.06	degradation of tyrosine
01.01.10.05.07	degradation of tryptophan
01.01.10.05.08	degradation of histidine
01.01.10.07	degradation of amino acids of the hydroxyamino-acid group
01.01.10.09	degradation of amino acids of the alanine-D-amino-acid group
01.01.99	other amino acid metabolism activities
01.02	nitrogen and sulfur metabolism
01.02.01	nitrogen and sulfur utilization
01.02.01.01	nitrogen fixation
01.02.01.03	nitrate dissimilation
01.02.01.05	ammonium nitrification
01.02.01.07	nitric oxide biosynthesis
01.02.01.09	catabolism of nitrogenous compounds
01.02.01.09.01	urea catabolism
01.02.01.09.03	urate catabolism
01.02.01.09.05	cyanate catabolism
01.02.01.09.99	other catabolism of nitrogenous compounds
01.02.01.11	sulfate assimilation
01.02.01.13	assimilatory reduction of sulfur
01.02.01.99	other nitrogen and sulfur utilization
01.02.04	regulation of nitrogen and sulphur utilization
01.02.04.01	regulation of nitrogen utilization
01.02.04.03	regulation of sulfur utilization
01.02.07	nitrogen and sulfur transport
01.02.07.01	N-transport
01.02.07.03	S-transport
01.02.99	other nitrogen and sulfur metabolism activities
01.03	nucleotide metabolism
01.03.01	purine ribonucleotide metabolism
01.03.01.01	purine ribonucleotide catabolism
01.03.01.01.01	hypoxanthine catabolism
01.03.01.01.03	xanthine catabolism
01.03.01.01.99	other purine ribonucleotide catabolism
01.03.01.03	purine ribonucleotide anabolism
01.03.04	pyrimidine ribonucleotide metabolism
01.03.04.01	pyrimidine ribonucleotide catabolism
01.03.04.03	pyrimidine ribonucleotide anabolism
01.03.07	deoxyribonucleotide metabolism
01.03.07.01	deoxyribonucleotide catabolism
01.03.07.03	deoxyribonucleotide anabolism
01.03.10	metabolism of cyclic and unusual nucleotides
01.03.13	regulation of nucleotide metabolism
01.03.16	polynucleotide degradation
01.03.16.01	RNA degradation
01.03.16.03	DNA degradation
01.03.19	nucleotide transport
01.03.99	other nucleotide-metabolism activities
01.04	phosphate metabolism
01.04.01	phosphate utilization
01.04.04	regulation of phosphate utilization
01.04.07	phosphate transport
01.04.99	other phosphate metabolism activities
01.05	C-compound and carbohydrate metabolism
01.05.01	C-compound and carbohydrate utilization
01.05.01.01	C-compound, carbohydrate catabolism
01.05.01.01.01	sugar, glucoside, polyol and carboxylate catabolism
01.05.01.01.02	polysaccharide degradation
01.05.01.01.03	C-2 compound and organic acid catabolism
01.05.01.01.04	aminosaccharide catabolism
01.05.01.01.05	C-1 compound catabolism
01.05.01.01.05.01	serine-isocitrate lyase pathway
01.05.01.01.05.03	ribulose-monophosphate cycle
01.05.01.01.07	aliphatic hydrocarbon catabolism
01.05.01.01.09	aerobic aromate catabolism
01.05.01.01.09.01	ortho-cleavage
01.05.01.01.09.03	meta-cleavage
01.05.01.01.11	anaerobic aromate catabolism
01.05.01.01.99	other C-compound, carbohydrate catabolism
01.05.01.03	C-compound, carbohydrate anabolism
01.05.01.03.01	sugar, glucoside, polyol and carboxylate anabolism
01.05.01.03.02	polysaccharide biosynthesis
01.05.01.03.03	C-2 compound and organic acid anabolism
01.05.01.03.04	aminosaccharide biosynthesis
01.05.01.03.05	C-1 compound anabolism
01.05.01.03.07	aliphatic hydrocarbon anabolism
01.05.01.03.09	aromate anabolism
01.05.01.03.99	other C-compound, carbohydrate anabolism
01.05.01.05	autotrophic CO2-fixation
01.05.01.05.01	Calvin cycle
01.05.01.05.03	reductive TCA cycle
01.05.01.05.05	hydroxypropionate pathway
01.05.01.05.07	acetyl-CoA pathway
01.05.01.07	transfer of activated C-1 groups
01.05.01.07.01	S-adenosyl-methionine--homocysteine cycle
01.05.01.07.03	tetrahydrofolate-dependent C-1-transfer
01.05.04	regulation of C-compound and carbohydrate utilization
01.05.07	C-compound, carbohydrate transport
01.05.99	other C-compound, carbohydrate metabolism activities
01.06	lipid, fatty-acid and isoprenoid metabolism
01.06.01	lipid, fatty-acid and isoprenoid biosynthesis
01.06.01.01	phospholipid biosynthesis
01.06.01.03	glycolipid biosynthesis
01.06.01.05	fatty acid biosynthesis
01.06.01.07	isoprenoid biosynthesis
01.06.01.07.01	hemiterpenes biosynthesis
01.06.01.07.03	monoterpenes biosynthesis
01.06.01.07.05	sesquiterpenes biosynthesis
01.06.01.07.07	diterpenes biosynthesis
01.06.01.07.09	triterpenes biosynthesis
01.06.01.07.11	tetracyclic and pentacyclic triterpenes (cholesterin, steroids and hopanoids) biosynthesis
01.06.01.07.13	tetraterpenes (carotinoids) biosynthesis
01.06.01.07.15	polyterpenes biosynthesis
01.06.04	breakdown of lipids, fatty acids and isoprenoids
01.06.07	lipid, fatty-acid and isoprenoid utilization
01.06.10	regulation of lipid, fatty-acid and isoprenoid metabolism
01.06.13	lipid and fatty-acid transport
01.06.99	other lipid, fatty-acid and isoprenoid metabolism activities
01.07	metabolism of vitamins, cofactors, and prosthetic groups
01.07.01	biosynthesis of vitamins, cofactors, and prosthetic groups
01.07.03	catabolism of vitamins, cofactors, and prosthetic groups
01.07.04	utilization of vitamins, cofactors, and prosthetic groups
01.07.07	regulation of vitamins, cofactors, and prosthetic groups metabolism
01.07.10	transport of vitamins, cofactors, and prosthetic groups
01.07.99	other vitamin, cofactor, and prosthetic group metabolism activities
01.20	secondary metabolism
01.20.01	metabolism of primary metabolic sugars derivatives
01.20.01.01	biosynthesis of secondary monosaccharides
01.20.01.03	biosynthesis of sugar carboxylic acids
01.20.01.05	biosynthesis of sugar alcohols
01.20.01.07	biosynthesis of glycosides
01.20.01.09	biosynthesis of aminoglycoside antibiotics
01.20.01.99	other biosynthesis of primary metabolic sugars derivatives
01.20.03	biosynthesis of derivatives of intermediates of glucose degradation
01.20.05	biosynthesis of acetic acid derivatives
01.20.05.01	biosynthesis of acetoacetate, acetone, hydroxybutyric acid
01.20.05.03	biosynthesis of alkanes, alkenes, alkanals, alkanols
01.20.05.05	biosynthesis of fatty acid esters
01.20.05.07	biosynthesis of acetylenes
01.20.05.09	biosynthesis of eicosanoids
01.20.05.11	biosynthesis of polyketides
01.20.05.99	other biosynthesis of acetic acid derivatives
01.20.07	biosynthesis of propionic acid derivatives
01.20.09	biosynthesis of derivatives of intermediates of the TCA and glyoxylate pathway
01.20.13	biosynthesis of derivatives of homoisopentenyl pyrophosphate
01.20.15	biosynthesis of derivatives of dehydroquinic acid, shikimic acid and chorismic acid
01.20.15.01	biosynthesis of naphthoquinone, anthraquinone
01.20.15.03	biosynthesis of ubiquinone
01.20.15.99	other biosynthesis of derivatives of dehydroquinic acid, shikimic acid and chorismic acid
01.20.17	biosynthesis of secondary products derived from primary amino acids
01.20.17.01	biosynthesis of nonprotein amino acids
01.20.17.03	biosynthesis of amines
01.20.17.05	biosynthesis of cyanogenic glycosides
01.20.17.07	biosynthesis of glycosinolates and derivatives
01.20.17.09	biosynthesis of alkaloids
01.20.19	biosynthesis of secondary products derived from glycine, L-serine and L-alanine
01.20.19.01	biosynthesis of porphyrins
01.20.19.03	biosynthesis of tetrapyrrols
01.20.19.05	biosynthesis of cobalamins
01.20.19.99	other biosynthesis of secondary products derived from glycine, L-serine and L-alanine
01.20.21	biosynthesis of sulfuric acid and L-cysteine derivatives
01.20.23	biosynthesis of secondary products derived from L-methionine
01.20.25	biosynthesis of secondary products derived from L-valin, L-leucin and L-isoleucin
01.20.27	biosynthesis of secondary products derived from L-aspartic acid and L-threonine
01.20.29	biosynthesis of secondary products derived from L-glutamic acid, L-proline and L-ornithine
01.20.31	biosynthesis of secondary products derived from L-lysine, L-arginine and L-histidine
01.20.33	biosynthesis of secondary products derived from L-tryptophan
01.20.35	biosynthesis of secondary products derived from L-phenylalanine and L-tyrosine
01.20.35.01	biosynthesis of phenylpropanoids
01.20.35.01.01	biosynthesis of melanins
01.20.35.01.03	biosynthesis of lignins
01.20.35.01.05	biosynthesis of stilbenes, flavonoids
01.20.35.01.07	biosynthesis of coumarins
01.20.35.01.09	biosynthesis of cinnamic acids
01.20.35.01.99	other biosynthesis of phenylpropanoids
01.20.35.02	biosynthesis of thyroids
01.20.35.03	biosynthesis of catecholamines
01.20.35.99	other biosynthesis of secondary products derived from L-phenylalanine and L-tyrosine
01.20.36	non-ribosomal peptide synthesis
01.20.37	biosynthesis of peptide derived compounds
01.20.37.01	biosynthesis of thioredoxin, glutaredoxin, glutathion
01.20.37.03	biosynthesis of peptide antibiotics
01.20.37.05	biosynthesis of beta-lactams
01.20.37.99	other biosynthesis of peptide derived compounds
01.20.50	catabolism of secondary metabolites
01.20.70	regulation of secondary metabolism
01.20.99	other secondary metabolism activities
01.25	extracellular metabolism
01.25.01	extracellular polysaccharide degradation
01.25.03	extracellular protein degradation
01.25.05	extracellular polynucleotides degradation
01.25.07	extracellular ester compounds degradation
01.25.09	extracellular lignin degradation
01.25.99	other extracellular metabolism
02	ENERGY
02.01	glycolysis and gluconeogenesis
02.01.01	glycolysis methylglyoxal bypass
02.01.03	regulation of glycolysis and gluconeogenesis
02.05	Entner-Doudoroff pathway
02.07	pentose-phosphate pathway
02.07.01	pentose-phosphate pathway oxidative branch
02.07.03	pentose-phosphate pathway non oxidative branch
02.07.05	regulation of pentose-phosphate pathway
02.08	pyruvate dehydrogenase complex
02.09	anaplerotic reactions
02.10	tricarboxylic-acid pathway (citrate cycle, Krebs cycle, TCA cycle)
02.11	electron transport and membrane-associated energy conservation
02.11.05	accessory proteins of electron transport and membrane-associated energy conservation
02.11.07	regulation of electron transport and membrane-associated energy conservation
02.11.99	other electron transport and membrane-associated energy conservation proteins
02.13	respiration
02.13.01	anaerobic respiration
02.13.03	aerobic respiration
02.13.05	regulation of respiration
02.16	fermentation
02.16.01	alcohol fermentation
02.16.01.01	bacterial type ethanol fermentation
02.16.01.99	other ethanol fermentation
02.16.03	lactate fermentation
02.16.03.01	homofermentative pathway
02.16.03.03	heterofermentative pathway and fermentaton of other saccharides
02.16.03.05	bifidum pathway
02.16.03.07	malo-lactate fermentation
02.16.05	butyrate and butanol-acetoine fermentation
02.16.07	ethanol-acetate fermentation
02.16.09	mixed acid and butanediol fermentation
02.16.11	propionate fermentation
02.16.11.01	acrylate pathway
02.16.11.03	succinate-propionate pathway
02.16.13	acetate fermentation
02.16.15	methane fermentation
02.16.17	fermentation of nitrogenous compounds
02.16.17.01	single amino acid fermentations
02.16.17.03	stickland reactions
02.16.17.05	fermentation of heterocyclic compounds
02.16.20	regulation of fermentation
02.16.99	other fermentation proteins
02.17	chemolithotrophie (sulfide, nitrogenous compounds)
02.19	metabolism of energy reserves (glycogen, trehalose)
02.22	glyoxylate cycle
02.25	oxidation of fatty acids
02.30	photosynthesis
02.30.10	regulation of photosynthesis
02.45	energy conversion
02.45.01	bioluminescence
02.45.03	light absorption
02.45.07	heat production
02.45.20	regulation of energy conversion
02.45.99	other energy conversion activities
02.99	other energy generation activities
03	CELL CYCLE AND DNA PROCESSING
03.01	DNA processing
03.01.01	cellular DNA uptake
03.01.01.01	bacterial competence
03.01.01.99	other cellular DNA uptake
03.01.03	DNA synthesis and replication
03.01.05	DNA recombination and DNA repair
03.01.05.01	DNA repair
03.01.05.01.01	nucleotide excision repair
03.01.05.01.99	other DNA repair
03.01.05.03	DNA recombination
03.01.05.03.01	meiotic recombination
03.01.05.03.03	somatic / mitotic recombination
03.01.05.03.05	DNA integration
03.01.05.03.99	other DNA recombination
03.01.09	DNA restriction or modification
03.01.09.01	DNA methylation
03.01.09.03	DNA restriction
03.01.09.05	chromatin modification
03.01.09.07	DNA imprinting
03.01.09.99	other DNA restriction or modification
03.01.11	regulation of DNA processing
03.01.99	other DNA processing
03.03	cell cycle
03.03.01	mitotic cell cycle and cell cycle control
03.03.01.01	mitotic cell cycle
03.03.01.01.01	G1 phase of mitotic cell cycle
03.03.01.01.03	G1/S transition of mitotic cell cycle
03.03.01.01.05	S phase of mitotic cell cycle
03.03.01.01.07	G2 phase of mitotic cell cycle
03.03.01.01.09	G2/M transition of mitotic cell cycle
03.03.01.01.11	mitosis
03.03.01.01.13	M/G1 transition of mitotic cell cycle
03.03.01.02	cell cycle arrest
03.03.01.03	cell cycle checkpoints (checkpoints of morphogenesis, DNA-damage,-replication, mitotic phase and spindle)
03.03.02	meiosis
03.03.02.01	meiosis I
03.03.02.03	meiosis II
03.03.03	cytokinesis (cell division)
03.03.04	nuclear and chromosomal cycle
03.03.04.01	centromere/kinetochore complex maturation
03.03.04.03	chromosome condensation
03.03.04.05	chromosome segregation
03.03.04.07	nuclear division
03.03.04.09	nuclear migration
03.03.04.99	other nuclear and chromosomal cycle related activities
03.03.05	cell cycle dependent cytoskeleton reorganization
03.03.05.01	spindle pole body/centrosome and microtubule cycle
03.03.05.03	cell cycle dependent actin filament reorganization
03.03.05.99	other cell cycle dependent cytoskeleton reorganization
03.99	other cell division and DNA synthesis activities
04	TRANSCRIPTION
04.01	rRNA transcription
04.01.01	rRNA synthesis
04.01.04	rRNA processing
04.01.99	other rRNA-transcription activities
04.03	tRNA transcription
04.03.01	tRNA synthesis
04.03.03	tRNA processing
04.03.06	tRNA modification
04.03.99	other tRNA-transcription activities
04.05	mRNA transcription
04.05.01	mRNA synthesis
04.05.01.01	general transcription activities
04.05.01.04	transcriptional control
04.05.01.04.01	transcriptional activator
04.05.01.04.03	transcriptional repressor
04.05.01.04.05	enhancer/silencer interaction
04.05.01.04.99	other transcriptional control
04.05.05	mRNA processing (splicing, 5'-, 3'-end processing)
04.05.05.01	splicing
04.05.05.01.10	regulation of splicing
04.05.05.01.99	other splicing activities
04.05.05.03	5'-end processing
04.05.05.05	3'-end processing
04.05.05.09	mRNA editing
04.05.05.11	control of mRNA stability
04.05.05.99	other mRNA processing
04.05.99	other mRNA-transcription activities
04.07	RNA transport
04.09	RNA localisation
04.99	other transcription activities
05	PROTEIN SYNTHESIS
05.01	ribosome biogenesis
05.01.01	ribosomal proteins
05.01.99	other ribosome biogenesis
05.04	translation
05.04.01	initiation
05.04.02	elongation
05.04.03	termination
05.07	translational control
05.10	aminoacyl-tRNA-synthetases
05.99	other protein-synthesis activities
06	PROTEIN FATE (folding, modification, destination)
06.01	protein folding and stabilization
06.04	protein targeting, sorting and translocation
06.07	protein modification
06.07.01	modification with fatty acids (e.g. myristylation, palmitylation, farnesylation)
06.07.02	modification with sugar residues (e.g. glycosylation)
06.07.02.01	O-directed glycosylation
06.07.02.02	N-directed glycosylation
06.07.02.99	other modification with sugar residues
06.07.03	modification by phosphorylation, dephosphorylation
06.07.04	modification by acetylation, deacetylation
06.07.05	modification by ubiquitination, deubiquitination
06.07.07	modification by ubiquitin-related proteins
06.07.09	posttranslational modification of amino acids (e.g. hydroxylation, methylation)
06.07.11	protein processing (proteolytic)
06.07.99	other protein modifications
06.10	assembly of protein complexes
06.13	proteolytic degradation
06.13.01	cytoplasmic and nuclear degradation
06.13.01.01	proteasomal degradation
06.13.04	lysosomal and vacuolar degradation
06.13.04.01	lysosomal degradation
06.13.04.02	vacuolar degradation
06.13.99	other proteolytic degradation
06.99	other protein fate related activities
08	CELLULAR TRANSPORT AND TRANSPORT MECHANISMS
08.01	nuclear transport
08.02	chloroplast transport
08.04	mitochondrial transport
08.05	non-vesicular ER transport
08.07	vesicular transport (Golgi network, etc.)
08.07.03	ER to golgi transport
08.07.05	intra golgi transport
08.07.07	post golgi transport
08.07.22	endocytosis
08.07.22.01	receptor-mediated endocytosis
08.07.22.03	constitutive endocytosis
08.07.25	vesicle formation
08.07.27	vesicle fusion
08.07.29	vesicle recycling
08.07.99	other vesicular trafficking pathways
08.10	peroxisomal transport
08.13	vacuolar transport
08.16	extracellular transport, exocytosis and secretion
08.16.03	Type I protein secretion system (ABC-type transport systems)
08.16.05	Type II protein secretion system (general secretory pathway, exocytosis)
08.16.07	Type III protein secretion system (virulence related secretory pathway, gram- bacteria specific)
08.16.09	Type IV protein secretion system (conjugal DNA-protein transfer)
08.16.11	Type V protein secretion system (MttABC or TatABCDE-system)
08.16.99	other export and secretion systems
08.19	cellular import
08.19.01	non-vesicular cellular import
08.19.03	vesicular cellular import
08.22	cytoskeleton-dependent transport
08.22.01	tubuline dependent transport
08.22.02	actin dependent transport
08.99	other intracellular transport activities
10	CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM
10.01	intracellular signalling
10.01.01	unspecified signal transduction
10.01.05	enzyme mediated signal transduction
10.01.05.01	protein kinase cascades
10.01.05.01.01	JAK-STAT cascade
10.01.05.01.02	JNK cascade
10.01.05.01.03	MAPKKK cascade
10.01.05.01.04	NIK-I-kappaB/NF-kappaB cascade
10.01.05.01.99	other protein kinase cascades
10.01.05.03	protease mediated signal transduction
10.01.05.05	G-protein mediated signal transduction
10.01.05.05.01	small GTPase mediated signal transduction
10.01.05.05.03	trimeric G-protein mediated signal transduction
10.01.09	second messenger mediated signal transduction
10.01.09.01	NO mediated signal transduction
10.01.09.03	Ca2+ mediated signal transduction
10.01.09.07	cAMP mediated signal transduction
10.01.09.09	fatty acid derivatives mediated signal transduction
10.01.09.11	polyphosphoinositol mediated signal transduction
10.01.09.99	other second messenger mediated signal transduction
10.01.11	ligand-dependent nuclear receptors
10.01.99	other intracellular signal transduction activities
10.05	transmembrane signal transduction
10.05.01	receptor enzyme mediated signalling
10.05.01.05	interleukine-receptor signalling pathway
10.05.01.10	two-component signal transduction system (phosphorelay)
10.05.01.12	transmembrane receptor protein tyrosine kinase signalling pathways
10.05.01.12.01	EGF-receptor signalling pathway
10.05.01.12.03	FGF-receptor signalling pathway
10.05.01.12.05	insulin receptor signalling pathway
10.05.01.12.99	other transmembrane receptor protein tyrosine kinase signalling pathways
10.05.01.18	transmembrane receptor protein serine/threonine kinase signalling pathways
10.05.01.18.01	TGFbeta-receptor signalling pathway
10.05.01.18.99	other transmembrane receptor protein serine/threonine kinase signalling pathways
10.05.02	non-enzymatic receptor mediated signalling
10.05.02.14	Notch-receptor signalling pathway
10.05.02.16	hedgehog-dependent signalling pathway
10.05.02.20	wnt signalling pathway
10.05.02.22	Tl-receptor (LRR proteins) signalling pathway
10.05.02.24	G-protein coupled receptor signalling pathway
10.05.02.26	integrin receptor signalling pathway
10.05.02.28	cadherin mediated signalling pathway
10.05.02.30	ion channel mediated signalling pathway
10.05.02.99	other non-enzymatic receptor mediated signalling
10.05.99	other transmembrane signal transduction mechanism
11	CELL RESCUE, DEFENSE AND VIRULENCE
11.01	stress response
11.01.01	oxydative stress response
11.01.03	osmotic and salt stress response
11.01.05	heat shock response
11.01.07	unfolded protein response (ER quality control)
11.01.09	DNA damage response
11.01.99	other stress response
11.05	Disease, virulence and defense
11.05.01	resistance proteins
11.05.03	defense related proteins
11.05.05	virulence, disease factors
11.05.05.01	toxins
11.05.05.03	bacteriocins
11.05.05.05	invasins
11.05.05.07	adhaesins
11.05.05.09	capsule
11.05.05.13	major antigenic determinants
11.05.05.99	other virulence, disease factors
11.05.99	other disease and defense related proteins
11.07	detoxification
11.07.01	detoxification involving cytochrome P450
11.07.03	detoxification by modification
11.07.05	detoxification by export
11.07.07	oxygen and radical detoxification
11.07.07.01	catalase reaction
11.07.07.03	glutathione conjugation reaction
11.07.07.05	peroxidase reaction
11.07.07.07	superoxide metabolism
11.07.99	other detoxification
11.10	degradation of foreign (exogenous) compounds
11.10.03	degradation of foreign (exogenous) polynucleotides
11.10.05	degradation of foreign (exogenous) proteins
11.10.07	degradation of foreign (exogenous) polysaccharides
11.10.09	degradation of foreign (exogenous) ester compounds
11.10.99	other degradation of foreign (exogenous) compounds
11.99	other cell rescue activities
13	REGULATION OF / INTERACTION WITH CELLULAR ENVIRONMENT
13.01	ionic homeostasis
13.01.01	homeostasis of cations
13.01.01.01	homeostasis of metal ions (Na, K, Ca etc.)
13.01.01.03	homeostasis of protons
13.01.01.99	homeostasis of other cations
13.01.03	homeostasis of anions
13.01.03.01	homeostasis of sulfates
13.01.03.03	homeostasis of phosphate
13.01.03.05	homeostasis of chloride
13.01.03.99	homeostasis of other anions
13.03	membrane excitability
13.03.01	synaptic transmission
13.03.03	action potential generation and propagation
13.03.05	regulation of membrane excitability
13.03.99	other membrane excitability activities
13.05	cell motility
13.05.01	cell migration
13.05.07	ciliary/flagellar motility
13.05.99	other cellular motility activities
13.07	cell adhesion
13.11	cellular sensing and response
13.11.01	photoperception and response
13.11.01.01	light environment response
13.11.01.03	visual transduction
13.11.01.05	phototaxis
13.11.01.99	other photoperception and response
13.11.03	chemoperception and response
13.11.03.01	perception of nutrients and nutritional adaptation
13.11.03.03	chemotaxis
13.11.03.05	chemical environment response
13.11.03.07	pheromone response
13.11.03.11	pH response
13.11.03.13	osmosensing
13.11.03.99	other chemoperception and response
13.11.05	mechanical stimulus perception and response
13.11.07	gravity perception and response
13.11.09	temperature perception and response
13.11.11	rhythm (e.g. circadian, ultradian)
13.11.99	other cellular sensing and response
14	CELL FATE
14.01	cell growth / morphogenesis
14.01.01	non-directional cell growth
14.01.03	directional cell growth (morphogenesis)
14.01.03.01	regulation of directional cell growth
14.01.03.03	guidance of longitudinal cell extension (eg. pollen tube guidance, axonal pathfinding)
14.01.03.99	other morphogenetic activities
14.01.05	growth regulators / regulation of cell size
14.01.05.01	interpretation of external signals that control cell growth
14.01.05.02	interpretation of nuclear/cytoplasmic ratio to control cell growth
14.01.99	other cell growth activities
14.04	cell differentiation
14.04.01	prokaryotic/unicellular/protist cell differentiation
14.04.01.01	differentiation of prokaryotes
14.04.01.01.01	sporulation and other development of resting stages
14.04.01.01.03	germination from resting stages
14.04.01.01.05	development of sporangia and cystophores
14.04.01.01.07	development of stalked or other sessile cells
14.04.01.01.09	development of swarmer and other mobile cells
14.04.01.01.99	other differentiation of prokaryotes
14.04.01.02	protist cell differentiation
14.04.03	fungal cell differentiation
14.04.03.01	budding, cell polarity and filament formation
14.04.03.03	pheromone response, mating-type determination, sex-specific proteins
14.04.03.05	sporulation and germination
14.04.03.07	hyphae formation
14.04.03.99	other fungal cell differentiation
14.04.05	plant cell differentiation (see 33 cell type differentiation)
14.04.07	animal cell differentiation (see 33 cell type differentiation)
14.04.09	extracellular differentiation regulators
14.04.09.01	cytokines (interleukines, colony stimulating factors etc.)
14.04.09.03	chemokines
14.04.09.05	growth factors
14.04.09.07	trophic factors
14.04.09.99	other extracellular differentiation regulators
14.05	dedifferentiation
14.10	cell death
14.10.02	apoptosis (type I programmed cell death)
14.10.02.01	anti-apoptosis
14.10.02.02	apoptotic program
14.10.02.02.01	apoptotic mitochondrial changes
14.10.02.02.02	caspase activation
14.10.02.02.03	disassembly of cell structures
14.10.02.02.04	induction of proapoptotic gene products
14.10.02.02.05	repression of survival gene products
14.10.02.03	induction of apoptosis
14.10.02.03.01	induction of apoptosis by extracellular signals
14.10.02.03.02	induction of apoptosis by intracellular signals
14.10.02.99	other apoptotic activity
14.10.90	other programmed cell death
14.10.99	other cell death
14.20	cell aging
14.99	other cell fate related activities
20	SYSTEMIC REGULATION OF / INTERACTION WITH ENVIRONMENT
20.03	nutrients uptake and absorption (eg. digestion)
20.05	osmoregulation and excretion
20.07	gas and metabolite distribution
20.07.01	gas exchange and distribution
20.07.03	control of respiratory activity
20.07.05	metabolite distribution
20.07.07	circulation
20.09	systemic temperature regulation
20.11	systemic rhythm control
20.20	plant / fungal specific systemic sensing and response
20.20.16	plant defense response
20.20.16.01	disease resistance (R-gene) specific
20.20.16.03	jasmonic acid/ethylene dependent systemic resistance
20.20.16.05	systemic acquired resistance
20.20.16.07	hypersensitive response
20.20.18	plant hormonal regulation
20.20.18.01	auxin response
20.20.18.02	ethylen response
20.20.18.03	gibberellic acid response
20.20.18.04	cytokinin response
20.20.18.05	abscisic acid response
20.20.18.06	brassinosteroid response
20.20.18.99	other plant signalling molecules response (jasmonic acid, salicylic acid etc.)
20.20.35	response to environmental stimuli
20.20.35.09	chemical environment sensing and response
20.20.35.09.01	water response and homeostasis
20.20.35.09.03	pH response
20.20.35.09.05	osmotic response
20.20.35.09.07	chemotropism
20.20.35.09.99	other chemical environment response
20.20.35.11	light sensing and response
20.20.35.11.01	phototropism
20.20.35.11.99	other light sensing and response
20.20.35.13	gravity sensing and response
20.20.35.13.01	gravitropism
20.20.35.13.99	other gravity sensing and response
20.20.35.15	mechanical stimulus response
20.20.99	other plant / fungal specific systemic sensing and response
20.25	animal specific systemic sensing and response
20.25.01	animal sensory mechanisms
20.25.01.01	vision
20.25.01.03	hearing
20.25.01.05	tactile sense (peripheral physical and mechanical stimuli perception)
20.25.01.07	sense of balance and equilibrium (vestibular pathways and mechanisms)
20.25.01.09	proprioceptive pathways and mechanisms
20.25.01.11	taste
20.25.01.13	olfaction
20.25.01.15	pain (nociceptive pathways)
20.25.01.99	other sensory mechanisms
20.25.03	nervous system physiology
20.25.03.01	nervous system mediated vegetative activities / neurosecretory activities
20.25.03.01.01	effect on glands / hormones
20.25.03.01.03	effect on smooth muscles
20.25.03.01.05	effect on heart muscle
20.25.03.03	nervous system mediated motor activity
20.25.03.03.01	neuromuscular junction-related activities
20.25.03.03.03	movement and posture coordination
20.25.03.04	neuronal integrative functions
20.25.03.04.01	learning and memory
20.25.03.99	other nervous system physiological activities
20.25.07	animal hormonal regulation
20.25.07.01	effect on kinetics (muscle contraction, pigment, gland secretion)
20.25.07.03	effect on homeostasis (e.g. metabolism or electrolyte homeostasis)
20.25.07.05	effect on morphogenesis
20.25.07.07	effect on behaviour
20.25.07.99	other hormonal response activity
20.25.09	muscle contraction
20.25.09.01	smooth muscle contraction
20.25.09.03	striated muscle contraction
20.25.09.05	general muscle contraction regulation
20.25.16	immune response
20.25.16.01	innate immune response (invertebrates and vertebrates)
20.25.16.01.01	complement response
20.25.16.01.03	phagocyte response (e.g. macrophages, dendritic cells, granulocytes)
20.25.16.01.05	cytotoxic cell response (e.g. NK)
20.25.16.01.07	Acute phase response (C-reactive protein)
20.25.16.01.99	other innate immune response
20.25.16.03	adaptive immune response (vertebrates)
20.25.16.03.01	humoral response (B cells)
20.25.16.03.03	adaptive cell mediated response (T cells)
20.25.16.03.05	antigen presentation / processing
20.25.16.03.07	immunological memory
20.25.16.03.99	other adaptive immune response
20.25.16.07	inflammatory response
20.25.16.09	blood coagulation
20.25.16.99	other immune response activities
20.25.99	other animal specific systemic sensing and response
20.99	other systemic regulation of / interaction with the environment
25	DEVELOPMENT (Systemic)
25.01	fungal/microorganismic development
25.01.01	mating (fertilization)
25.01.03	tissue pattern formation
25.01.03.01	fruit body development
25.01.03.03	mycelium development
25.01.99	other fungal development
25.03	plant development
25.03.01	gametophyte development
25.03.01.01	microspore development (male gametophyte)
25.03.01.02	macrospore development (female gametophyte)
25.03.02	fertilization (pollen hydration, pollen tube guidance, double fertilization of oocyte and endosperm)
25.03.03	embryonal development
25.03.03.01	zygote development
25.03.03.02	early embryo development (Dicotyledone pre-heart stages)
25.03.03.03	mid-stage embryo development (Dicotyledone heart to torpedo)
25.03.03.04	late-stage embryo development (Dicotyledone torpedo and later)
25.03.03.05	mature embryo development
25.03.04	endosperm development
25.03.05	germination
25.03.06	vegetative development
25.03.07	flower development
25.03.08	fruit development and ripening
25.03.10	senescence
25.03.99	other plant development
25.05	animal development
25.05.01	fertilization
25.05.02	embryo implantation (mammalia)
25.05.03	morula development
25.05.04	blastocyst (mammalia)
25.05.04.01	trophectoderm
25.05.04.03	inner cell mass
25.05.05	blastocoel development
25.05.07	blastulation
25.05.09	gastrulation
25.05.10	late embryonic development
25.05.11	extraembryonal tissue development
25.05.13	neurogenesis
25.05.15	myogenesis
25.05.17	osteogenesis
25.05.19	asymmetries and axis determination
25.05.19.01	vegetal pole determination
25.05.19.03	animal pole determination
25.05.19.05	anterior-posterior axis determination
25.05.19.07	dorso-ventral axis determination
25.05.19.09	medio-lateral axis determination
25.05.19.11	segment specification
25.05.21	extremities and appendages development
25.05.23	sex differentiation
25.05.25	gametogenesis
25.05.99	other animal development
29	TRANSPOSABLE ELEMENTS, VIRAL AND PLASMID PROTEINS
29.01	LTR retroelements (retroviral)
29.02	non-LTR retroelements
29.03	transposons
29.05	viral proteins
29.06	phage proteins
29.07	proteins necessary for the integration or inhibition of transposon movement
29.99	other transposable elements, viral and plasmid proteins
30	CONTROL OF CELLULAR ORGANIZATION
30.01	cell wall
30.02	plasma membrane
30.03	cytoplasm
30.04	cytoskeleton
30.04.03	actin cytoskeleton
30.04.05	microtubule cytoskeleton
30.04.07	intermediate filaments
30.04.99	other cytoskeleton components
30.05	centrosome
30.06	cell junction
30.06.03	cell-substrate adherens junction
30.06.04	intercellular junction (gap junction/adherens junction)
30.06.99	other cell junction structures
30.07	endoplasmic reticulum
30.08	Golgi
30.09	intracellular transport vesicles
30.10	nucleus
30.10.03	organization of chromosome structure
30.10.05	nuclear membrane
30.10.07	nucleolus
30.10.99	other nuclear structures
30.16	mitochondrion
30.19	peroxisome
30.22	endosome
30.25	vacuole or lysosome
30.26	plastid
30.26.03	chloroplast
30.26.05	amyloplast
30.26.07	chromoplast
30.26.09	elaioplast
30.26.11	etioplast
30.26.13	leucoplast
30.26.99	other plastids
30.27	extracellular / secretion proteins
30.27.01	extracellular matrix
30.27.99	other extracellular structures
30.28	periplasmatic space
30.30	prokaryotic cell membrane (inner membrane of gram-)
30.32	flagellum
30.31	bacterial outer membrane (gram-)
30.33	pilus/fimbria
30.34	prokaryotic cell surface structures
30.34.03	capsule and slime layer
30.34.05	S-Layer
30.34.07	peptidoglycan layer or other prokaryotic cell-wall
30.34.09	spore or cyst coat
30.34.99	other prokaryotic cell surface structures
30.35	prokaryotic intracytoplasmic membrane
30.35.03	prokaryotic vesicular intracytoplasmic membrane
30.35.05	prokaryotic tubular intracytoplasmic membrane
30.35.07	prokaryotic thylakoid-like and thylakoid membrane
30.35.99	other prokaryotic intracytoplasmic membranes
30.36	prokaryotic cell inclusions
30.37	prokaryotic nucleoid
30.99	other control of cellular organization
33	CELL TYPE DIFFERENTIATION
33.01	fungal/microorganismic cell type control
33.01.01	vegetative prokaryotic cell or mycelium
33.01.01.01	free living cell or mycelium
33.01.01.02	sporangial or cystophor cell
33.01.01.03	heterocyste
33.01.01.99	other vegetative prokaryotic cell or mycelium
33.01.02	reproductive prokaryotic cell
33.01.02.01	swarmer cell
33.01.02.02	endospore
33.01.02.03	exospore, cyst, akinete or other resting cells
33.01.02.99	other reproductive prokaryotic cell
33.01.03	vegetative eukaryotic cell
33.01.03.01	free swimming or amoeboid cell
33.01.03.02	mycelial or yeast-like cell
33.01.03.03	thallic, plasmodial or sporangiophore cell
33.01.03.99	other fungal/microorganismic vegetative eukaryotic cell
33.01.04	reproductive eukaryotic cell
33.01.04.01	conidia
33.01.04.02	asco- basidio- or zygospore
33.01.04.03	cyst
33.01.04.99	other reproductive eukaryotic cell
33.01.99	other fungal/microorganismic cell type
33.02	plant cell type differentiation
33.02.01	stem cell/meristematic cell
33.02.05	epidermal cell
33.02.05.01	stomata/guard cell
33.02.05.02	plant hair cell (trichome eg. cotton)
33.02.05.03	root hair
33.02.05.99	other epidermal cell
33.02.07	storage cell
33.02.09	vascular cell
33.02.09.01	sieve cell (phloem)
33.02.09.02	companion cell (phloem)
33.02.09.03	vessel element (xylem)
33.02.11	mesenchymal / parenchymal cell
33.02.13	strengthening cell
33.02.13.01	sclerenchyma cell(dead)
33.02.13.02	collenchyma cell (living)
33.02.17	gametophytic cell
33.02.17.01	male gametophyte
33.02.17.01.01	generative pollen cell
33.02.17.01.99	other male gametophytic cell
33.02.17.02	female gametophyte
33.02.17.02.01	oocyte
33.02.17.02.03	central cell (2n)
33.02.17.02.99	other female gametophytic cell
33.02.19	secretory cell
33.02.99	other plant cell type differentiation
33.03	animal cell type differentiation
33.03.01	stem cell (toti- or pluripotent)
33.03.02	germ cell
33.03.03	pigment cell
33.03.07	oxygen transporting cell (erythrocyte etc.)
33.03.09	immune cell
33.03.09.01	T-cell
33.03.09.03	B-cell
33.03.09.05	macrophage
33.03.09.07	dendritic cell
33.03.09.99	other immune cell
33.03.11	glia cell
33.03.13	neuron
33.03.15	secretory cell (mastcell, endocrine cell etc.)
33.03.17	structural cell of tissue (fibroblast, osteoblast, etc.)
33.03.18	storage cell (lipocyte etc.)
33.03.19	extracellular matrix forming cell (fibrocyte, chondrocyte, osteocyte)
33.03.21	extracellular matrix degrading cell (chondroclast, osteoclast)
33.03.23	sensory cell
33.03.99	other animal cell type differentiation
35	TISSUE DIFFERENTIATION
35.01	fungal/microorganismic tissue
35.01.01	reproductive tissue
35.01.10	thallic tissue
35.01.11	plectenchymatic tissue and tissue of primitive thalli (eg. higher fungi)
35.01.99	other fungal/microorganismic tissue
35.02	plant tissue
35.02.01	meristematic tissue
35.02.01.01	shoot apical meristem
35.02.01.02	root meristem
35.02.01.05	other meristematic tissues
35.02.05	parenchyma
35.02.09	dermal tissue
35.02.09.01	epidermis
35.02.09.03	rhizodermis
35.02.09.05	secondary dermal tissue (cork, phellem)
35.02.09.07	endodermis (with casparian band)
35.02.09.99	other dermal tissue
35.02.13	vascular tissue
35.02.15	thallus
35.02.99	other plant tissue
35.03	animal tissue
35.03.03	proliferative tissue
35.03.05	connective tissue
35.03.05.01	loose connective tissue / soft tissue
35.03.05.03	fibrous connective tissue (tendons, ligaments)
35.03.05.05	cartilage
35.03.05.07	bone
35.03.05.09	whole blood and lymph
35.03.05.11	adipose tissue
35.03.05.99	other connective tissue
35.03.09	epithelium
35.03.12	muscle
35.03.12.01	striated muscle
35.03.12.02	smooth muscle
35.03.12.03	heart muscle
35.03.15	reproductive tissue
35.03.17	nervous tissue
35.03.19	glandular tissue
35.03.99	other animal tissue
37	ORGAN DIFFERENTIATION
37.01	fungal organ
37.01.01	hyphe
37.01.03	reproductive organ
37.01.03.01	fruit body
37.01.03.99	other reproductive organs
37.01.99	other fungal organs
37.02	plant organ
37.02.01	shoot
37.02.01.01	stem
37.02.01.02	leaf
37.02.01.03	flower
37.02.01.03.01	sepal
37.02.01.03.02	petal
37.02.01.03.03	anther
37.02.01.03.04	carpel
37.02.01.03.99	other flower organs
37.02.01.04	fruit
37.02.01.05	seed
37.02.01.05.01	embryo
37.02.01.05.02	endosperm
37.02.01.05.99	other seed components
37.02.01.06	rhizome (potato tuber/onion)
37.02.01.99	other shoot components
37.02.02	root
37.02.99	other plant organs
37.03	animal organ
37.03.01	nervous system
37.03.01.01	central nervous system
37.03.01.01.01	brain
37.03.01.01.01.01	cerebrum
37.03.01.01.01.02	cerebellum
37.03.01.01.01.99	other brain areas
37.03.01.01.99	other central nervous system districts
37.03.01.02	peripheral nervous system
37.03.02	sensory organs
37.03.03	vascular organs
37.03.03.01	heart
37.03.03.02	vessels
37.03.03.99	other vascular organs
37.03.05	immune system organs
37.03.05.01	thymus
37.03.05.02	spleen
37.03.05.03	lymphatic system
37.03.05.99	other immune system organs
37.03.07	excretory apparatus
37.03.07.01	kidney
37.03.07.03	malphigi
37.03.07.05	pronephros (sensu Invertebrata)
37.03.07.07	metanephros (sensu Invertebrata)
37.03.07.99	other excretory apparatus organs
37.03.09	respiratory system
37.03.09.01	lung
37.03.09.03	gill
37.03.09.05	trachea (sensu Insecta)
37.03.09.99	other respiratory system organs
37.03.11	gastro-intestinal system
37.03.11.01	teeth
37.03.11.02	oesophagus
37.03.11.03	stomach
37.03.11.05	intestine
37.03.11.07	liver
37.03.11.09	pancreas
37.03.11.11	gastro-intestinal system accessory organs
37.03.11.99	other gastro-intestinal system organs
37.03.13	dermis/cuticula
37.03.13.05	hair / feather follicule
37.03.13.99	other dermal organs
37.03.15	reproductive apparatus
37.03.15.01	female gonad (ovary)
37.03.15.04	uterus
37.03.15.04.03	cervix
37.03.15.05	placenta
37.03.15.07	male gonad (testis)
37.03.15.09	prostate
37.03.15.99	other reproductive apparatus organs
37.03.17	skeletal system
37.03.19	non-organ cavities and their linings
37.03.21	secretory organs (glands)
37.03.21.01	mammary gland
37.03.21.02	salivary gland
37.03.21.02	sweat (perspiratory) gland
37.03.21.03	endocrine organ
37.03.21.03.01	adrenal gland
37.03.21.03.02	pancreatic islet
37.03.21.03.03	parathyroid
37.03.21.03.04	pineal gland
37.03.21.03.05	pituitary gland
37.03.21.03.06	thyroid gland
37.03.21.99	other glands
37.03.99	other animal organs
40	SUBCELLULAR LOCALISATION
40.01	cell wall
40.02	plasma membrane
40.03	cytoplasm
40.04	cytoskeleton
40.04.03	actin cytoskeleton
40.04.05	microtubule cytoskeleton
40.04.07	intermediate filaments
40.04.99	other cytoskeleton components
40.05	centrosome
40.06	cell junction
40.06.03	cell-substrate adherens junction
40.06.04	intercellular junction (gap junction/adherens junction)
40.06.99	other cell junction structures
40.07	endoplasmic reticulum
40.08	Golgi
40.09	intracellular transport vesicles
40.10	nucleus
40.10.03	chromosome
40.10.05	nuclear membrane
40.10.07	nucleolus
40.10.99	other nuclear structures
40.16	mitochondrion
40.19	peroxisome
40.22	endosome
40.25	vacuole or lysosome
40.26	plastid
40.26.03	chloroplast
40.26.05	amyloplast
40.26.07	chromoplast
40.26.09	elaioplast
40.26.11	etioplast
40.26.13	leucoplast
40.26.99	other plastids
40.27	extracellular / secretion proteins
40.27.01	extracellular matrix component
40.27.99	other extracellular components
40.28	periplasmatic space
40.30	prokaryotic cell membrane (inner membrane of gram - bacteria)
40.31	bacterial outer membrane
40.32	flagellum
40.33	pilus/fimbria
40.34	prokaryotic cell surface component
40.34.03	capsule and slime layer
40.34.05	S-Layer
40.34.07	peptidoglycan layer or other prokaryotic cell-wall
40.34.09	spore or cyst coat
40.34.99	other prokaryotic cell surface components
40.35	prokaryotic intracytoplasmic membrane
40.35.03	prokaryotic vesicular intracytoplasmic membrane
40.35.05	prokaryotic tubular intracytoplasmic membrane
40.35.07	prokaryotic thylakoid-like and thylakoid membrane
40.35.99	other prokaryotic intracytoplasmic membranes
40.36	prokaryotic cell inclusions
40.36.03	carboxysomes
40.36.05	gas vesicles
40.36.07	sulfur globules or magnetosomes
40.36.09	bacteriocins, rhapidosomes and protein crystals
40.36.99	other prokaryotic cell inclusions
40.37	prokaryotic nucleoid
40.99	other subcellular localisation
43	CELL TYPE LOCALISATION
43.01	fungal / microorganismic cell type
43.01.01	vegetative prokaryotic cell or mycelium
43.01.01.01	free living cell or mycelium
43.01.01.02	sporangial or cystophor cell
43.01.01.03	heterocyste
43.01.01.99	other vegetative prokaryotic cell or mycelium
43.01.02	reproductive prokaryotic cell
43.01.02.01	swarmer cell
43.01.02.02	endospore
43.01.02.03	exospore, cyst, akinete or other resting cells
43.01.02.99	other reproductive prokaryotic cell
43.01.03	vegetative eukaryotic cell
43.01.03.01	free swimming or amoeboid cell
43.01.03.02	mycelial or yeast-like cell
43.01.03.03	thallic, plasmodial or sporangiophore cell
43.01.03.99	other fungal/microorganismic vegetative eukaryotic cell
43.01.04	reproductive eukaryotic cell
43.01.04.01	conidia
43.01.04.02	asco- basidio- or zygospore
43.01.04.03	cyst
43.01.04.99	other reproductive eukaryotic cell
43.01.99	other fungal / microorganismic cell type
43.02	plant cell type
43.02.01	stem cell/meristematic cell
43.02.05	specialized epidermal cell
43.02.05.01	stomata/guard cell
43.02.05.02	plant hair cell (trichome eg. cotton)
43.02.05.03	root hair
43.02.05.99	other specialized epidermal cell
43.02.07	storage cell
43.02.09	vascular cell
43.02.09.01	sieve cell (phloem)
43.02.09.02	companion cell (phloem)
43.02.09.03	vessel element (xylem)
43.02.13	strengthening cell
43.02.13.01	sclerenchyma cell(dead)
43.02.13.02	collenchyma cell (living)
43.02.17	gametophytic cell
43.02.17.01	male gametophyte
43.02.17.01.01	generative pollen cell
43.02.17.01.99	other male gametophytic cell
43.02.17.02	female gametophyte
43.02.17.02.01	oocyte
43.02.17.02.03	central cell (2n)
43.02.17.02.99	other female gametophytic cell
43.02.19	secretory cell
43.02.99	other plant cell localisation
43.03	animal cell type
43.03.01	stem cell (toti- or pluripotent)
43.03.02	germ cell
43.03.03	pigment cell
43.03.07	oxygen transporting cell (erythrocyte etc.)
43.03.09	immune cell
43.03.09.01	T-cell
43.03.09.03	B-cell
43.03.09.05	macrophage
43.03.09.07	dendritic cell
43.03.09.99	other immune cell
43.03.11	glia cell
43.03.13	neuron
43.03.15	secretory cell (mastcell, endocrine cell etc.)
43.03.17	structural cell of tissue (fibroblast, osteoblast, etc.)
43.03.18	storage cell (lipocyte etc.)
43.03.19	extracellular matrix forming cell (fibrocyte, chondrocyte, osteocyte)
43.03.21	extracellular matrix degrading cell (chondroclast, osteoclast)
43.03.23	sensory cell
43.03.99	other animal cell type localisation
45	TISSUE LOCALISATION
45.01	fungal/microorganismic tissue
45.01.01	reproductive tissue
45.01.10	thallic tissue
45.01.11	plectenchymatic tissue and tissue of primitive thalli ( eg. higher fungi )
45.01.99	other fungal/microorganismic tissue
45.02	plant tissue
45.02.01	meristematic tissue
45.02.01.01	shoot apical meristem
45.02.01.02	root meristem
45.02.01.05	other meristematic tissues
45.02.05	parenchyma
45.02.09	dermal tissue
45.02.09.01	epidermis
45.02.09.03	rhizodermis
45.02.09.05	secondary dermal tissue (cork, phellem)
45.02.09.07	endodermis (with casparian band)
45.02.09.99	other dermal tissue
45.02.13	vascular tissue
45.02.15	thallus
45.02.99	other plant tissue
45.03	animal tissue
45.03.03	proliferative tissue
45.03.03.01	bone marrow
45.03.03.99	other proliferative tissue
45.03.05	connective tissue
45.03.05.01	loose connective tissue / soft tissue
45.03.05.03	fibrous connective tissue (tendons, ligaments)
45.03.05.05	cartilage
45.03.05.07	bone
45.03.05.09	whole blood and lymph
45.03.05.11	adipose tissue
45.03.05.99	other connective tissue
45.03.09	epithelium
45.03.12	muscle
45.03.12.01	striated muscle
45.03.12.02	smooth muscle
45.03.12.03	heart muscle
45.03.15	reproductive tissue
45.03.17	nervous tissue
45.03.19	glandular tissue
45.03.99	other animal tissue
47	ORGAN LOCALISATION
47.01	fungal organ
47.01.01	hyphe
47.01.03	reproductive organ
47.01.03.01	fruit body
47.01.03.99	other reproductive organs
47.01.99	other fungal organs
47.02	plant organ
47.02.01	shoot
47.02.01.01	stem
47.02.01.02	leaf
47.02.01.03	flower
47.02.01.03.01	sepal
47.02.01.03.02	petal
47.02.01.03.03	anther
47.02.01.03.04	carpel
47.02.01.03.99	other flower organs
47.02.01.04	fruit
47.02.01.05	seed
47.02.01.05.01	embryo
47.02.01.05.02	endosperm
47.02.01.05.99	other seed components
47.02.01.06	rhizome (potato tuber/onion)
47.02.01.99	other shoot components
47.02.02	root
47.02.99	other plant organ
47.03	animal organ
47.03.01	nervous system
47.03.01.01	central nervous system
47.03.01.01.01	brain
47.03.01.01.01.01	cerebrum
47.03.01.01.01.02	cerebellum
47.03.01.01.01.99	other brain areas
47.03.01.01.99	other central nervous system districts
47.03.01.02	peripheral nervous system
47.03.02	sensory organs
47.03.03	vascular organs
47.03.03.01	heart
47.03.03.02	vessels
47.03.03.99	other vascular organs
47.03.05	immune system organs
47.03.05.01	thymus
47.03.05.02	spleen
47.03.05.03	lymphatic system
47.03.05.99	other immune system organs
47.03.07	excretory apparatus
47.03.07.01	kidney
47.03.07.03	malphigi
47.03.07.05	pronephros (sensu Invertebrata)
47.03.07.07	metanephros (sensu Invertebrata)
47.03.07.99	other excretory apparatus organs
47.03.09	respiratory system
47.03.09.01	lung
47.03.09.03	gill
47.03.09.05	trachea (sensu Insecta)
47.03.09.99	other respiratory system organs
47.03.11	gastro-intestinal system
47.03.11.01	teeth
47.03.11.02	oesophagus
47.03.11.03	stomach
47.03.11.05	intestine
47.03.11.07	liver
47.03.11.09	pancreas
47.03.11.11	gastro-intestinal system accessory organs
47.03.11.99	other gastro-intestinal system organs
47.03.13	dermis/cuticula
47.03.13.05	hair / feather follicule
47.03.13.99	other dermal organs
47.03.15	reproductive apparatus
47.03.15.01	female gonad (ovary)
47.03.15.04	uterus
47.03.15.04.03	cervix
47.03.15.05	placenta
47.03.15.07	male gonad (testis)
47.03.15.09	prostate
47.03.15.99	other reproductive apparatus organs
47.03.17	skeletal system
47.03.19	non organ cavities and their linings
47.03.21	secretory organs (glands)
47.03.21.01	mammary gland
47.03.21.02	salivary gland
47.03.21.02	sweat (perspiratory) gland
47.03.21.03	endocrine organ
47.03.21.03.01	adrenal gland
47.03.21.03.02	pancreatic islet
47.03.21.03.03	parathyroid
47.03.21.03.04	pineal gland
47.03.21.03.05	pituitary gland
47.03.21.03.06	thyroid gland
47.03.21.99	other glands
47.03.99	other animal organs
48	ubiquitous expression
62	PROTEIN ACTIVITY REGULATION
62.01	mechanism of regulation
62.01.01	modification
62.01.03	localisation
62.01.05	processing
62.01.07	binding / dissociation
62.01.99	other mechanism of regulation
62.02	target of regulation
62.02.01	enzymatic activity regulation / enzyme regulator
62.02.01.01	enzyme activator
62.02.01.01.01	GTPase activator (GAP)
62.02.01.01.03	protease activator
62.02.01.01.05	kinase activator
62.02.01.01.99	other enzyme activator
62.02.01.02	enzyme inhibitor
62.02.01.02.01	GTPase inhibitor (GIP)
62.02.01.02.03	protease inhibitor
62.02.01.02.05	kinase inhibitior
62.02.01.02.99	other enzyme inhibitor
62.02.03	guanyl-nucleotide exchange factor (GEF)
62.02.05	regulator of G-protein signalling
62.02.07	regulator of receptor activity
62.02.99	other target of regulation
63	PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
63.01	protein binding
63.02	peptide binding
63.03	nucleic acid binding
63.03.01	DNA binding
63.03.03	RNA binding
63.05	polysaccharide binding
63.06	motor protein
63.07	structural protein
63.09	lipid binding
63.11	amino acid binding
63.13	C-compound binding
63.13.01	sugar binding
63.13.03	fatty acid binding (eg acyl-carrier protein)
63.13.99	other C-compound binding
63.17	metal binding
63.17.01	calcium binding
63.17.03	potassium binding
63.17.05	sodium binding
63.17.07	magnesium binding
63.17.09	heavy metal binding (Cu, Fe, Zn)
63.17.11	other metal binding
63.19	nucleotide binding
63.19.01	cAMP binding
63.19.03	ATP binding
63.19.05	GTP binding
63.19.99	other nucleotide binding
63.21	complex cofactor binding
63.21.01	heme binding
63.21.03	molybdopterin binding
63.21.05	FAD/FMN binding
63.21.07	NAD/NADP binding
63.21.09	cobalamin binding
63.21.11	thiamin pyrophosphate binding
63.21.13	lipoamid binding
63.21.15	biotin binding
63.21.17	pyridoxal phosphate binding
63.21.99	other complex cofactor binding
63.99	other binding function
65	STORAGE PROTEIN
67	TRANSPORT FACILITATION
67.01	channel / pore class transporters
67.01.01	ion channels
67.01.03	gap-junction forming protein family (e.g. connexin, innexin)
67.01.05	nuclear pore forming protein
67.01.07	general bacterial porin family (e.g. ompf, sugar porin, omf)
67.01.09	pore-forming toxins (e.g. diphteria toxin, hemolysin)
67.01.99	other channels and pores forming proteins
67.04	ion transporters
67.04.01	cation transporters
67.04.01.01	heavy metal ion transporters (Cu, Fe, etc.)
67.04.01.01.01	siderophore-iron transporter
67.04.01.01.02	citrate-iron transporter
67.04.01.02	other cation transporters (Na, K, Ca , NH4, etc.)
67.04.07	anion transporters (Cl, SO4, PO4, etc.)
67.04.07.01	nitrate transporter
67.04.07.03	nitrite transporter
67.04.07.05	sulfate transporter
67.04.07.07	phosphate transporter
67.04.07.09	chloride transporter
67.04.07.99	other anion transporters
67.07	C-compound and carbohydrate transporters
67.07.01	phosphotransferase system
67.07.03	C4-dicarboxylate transporter (e.g. malate, succinate, fumarate)
67.07.99	other C-compound transporters
67.10	amino-acid transporters
67.11	peptide transporters
67.12	amine / polyamine transporters
67.13	lipid transporters
67.15	electron / hydrogen carrier
67.16	nucleotide transporters
67.17	nucleoside transporters
67.19	allantoin and allantoate transporters
67.21	vitamin/cofactor transporters
67.28	drug transporters
67.50	transport mechanism
67.50.01	uniporter
67.50.03	symporters
67.50.03.01	proton driven symporter
67.50.03.03	sodium driven symporter
67.50.03.99	other symporters
67.50.05	antiporters
67.50.05.01	proton driven antiporter
67.50.05.03	sodium driven antiporter
67.50.05.99	other antiporters
67.50.22	transport ATPases
67.50.25	ABC transporters
67.50.99	other transport mechanisms
67.99	other transport facilitators
96	OUT OF USE (Historical categories, please update annotation for all ORFs in this categorie)
98	CLASSIFICATION NOT YET CLEAR-CUT
99	UNCLASSIFIED PROTEINS