-- dump date   	20111111_072859
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
NP_878038.1	Yal067w-ap
NP_009333.1	Seo1p
NP_009335.1	Yal065cp
NP_009336.1	Yal064w-bp
NP_058136.1	Yal064c-ap
NP_009337.1	Yal064wp
NP_878039.1	Yal063c-ap
NP_009338.1	Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation
NP_009339.1	NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources
NP_009340.1	Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene
NP_009341.1	NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source
NP_009342.1	Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export
NP_009343.1	Cne1p
NP_009345.2	Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p
NP_009346.1	Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation
NP_009347.1	Acs1p
NP_009348.1	Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance
NP_009349.2	Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis
NP_009350.1	Cytoplasmic protein of unknown function, potential Hsp82p interactor; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)
NP_009351.1	Gem1p
NP_009352.1	Spc72p
NP_009353.1	Putative protein of unknown function; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_075206.1	Yal044w-ap
NP_009355.2	H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm
NP_009356.1	Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII
NP_009358.1	Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fusion stage of transport
NP_009359.1	Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing
NP_009360.1	G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis
NP_009361.1	Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)
NP_009362.1	Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
NP_878040.1	Yal037c-ap
NP_009363.1	Yal037wp
NP_009364.1	Rbg1p
NP_009365.1	GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2
NP_009367.1	Mtw1p
NP_009368.2	Non-essential protein of unknown function
NP_009369.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
NP_009370.1	Prp45p
NP_009371.1	Gip4p
NP_009372.1	Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins
NP_009373.1	One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p
NP_009374.1	Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate
NP_009375.1	Saw1p
NP_009376.1	Drs2p
NP_009377.1	Mak16p
NP_009378.1	Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP
NP_009379.2	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals
NP_009380.1	Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes
NP_009381.1	Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening
NP_009382.1	Protein required, with Elongator complex, Kti11p, and Kti12p, for modification of wobble nucleosides in tRNA; has a potential role in regulatory interactions between microtubules and the cell cycle
NP_009383.1	Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_009384.1	Yal018cp
NP_009385.1	Psk1p
NP_009386.1	Tpd3p
NP_009387.1	Ntg1p
NP_009388.2	Syn8p
NP_009389.2	Transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation
NP_009390.1	Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine
NP_009391.2	Swc3p
NP_009392.1	Subunit of both the Mdm10-Mdm12-Mmm1 complex and the mitochondrial sorting and assembly machinery (SAM complex); functions in both the general and Tom40p-specific pathways for import and assembly of outer membrane beta-barrel proteins
NP_009393.1	Spo7p
NP_009394.1	Mitochondrial protein of unknown function
NP_009395.1	Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
NP_009396.2	Ssa1p
NP_009398.1	Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
NP_009399.2	Vps8p
NP_009400.1	Tfc3p
NP_009401.1	Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance
NP_009402.1	Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
NP_009403.1	Swd1p
NP_009404.1	Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
NP_009405.1	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease
NP_009406.1	Yar009cp
NP_009407.1	Yar010cp
NP_009408.2	Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cortical regulator of dynein; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_009409.1	N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine
NP_009410.1	Nonessential protein kinase with unknown cellular role
NP_009411.1	Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p
NP_009412.1	Pau7p
NP_009413.1	Yar023cp
NP_009414.1	Uip3p
NP_009415.1	Yar028wp
NP_009416.1	Yar029wp
NP_009418.1	Prm9p
NP_009419.1	Putative integral membrane protein, involved in vesicle formation; forms complex with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles
NP_009420.1	Yat1p
NP_878042.1	Yar035c-ap
NP_009421.3	Swh1p
NP_009424.1	Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p
NP_009429.1	Yar064wp
NP_009430.1	Yar066wp
NP_009431.1	Yar068wp
NP_009434.1	Pho11p
NP_009437.1	Ybl113cp
NP_009438.1	Ybl112cp
NP_009439.1	Ybl111cp
NP_076873.1	hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
NP_009443.1	Ybl107cp
NP_009444.1	Sro77p
NP_009445.1	Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)
NP_009446.2	Ybl104cp
NP_009447.1	Rtg3p
NP_009448.1	Sft2p
NP_009449.1	Non-essential protein of unknown function; promoter contains several Gcn4p binding elements
NP_878043.1	Ybl100w-cp
NP_009450.1	Ybl100w-bp
NP_009451.1	Ybl100w-ap
NP_009453.1	Atp1p
NP_009454.1	Kynurenine 3-mono oxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
NP_009455.2	Essential protein required for chromosome condensation, likely to function as an intrinsic component of the condensation machinery, may influence multiple aspects of chromosome transmission and dynamics
NP_009457.1	Ybl095wp
NP_009459.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme
NP_009460.1	Rpl32p
NP_009461.2	Scs22p
NP_009462.1	Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p
NP_009463.1	Mrp21p
NP_009464.2	Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
NP_009465.1	Tel1p
NP_009466.1	Rpl23ap
NP_009467.1	Ybl086cp
NP_009468.1	Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
NP_009469.1	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_009471.1	Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins
NP_009472.1	Ybl081wp
NP_009473.1	Protein required for mitochondrial translation; mutation is functionally complemented by a Bacillus subtilis ortholog
NP_009474.1	Nup170p
NP_009475.1	Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, and Atg3p, and conjugated at the C terminus with phosphatidylethanolamine, to become the form essential for generation of autophagosomes
NP_009477.1	Ils1p
NP_009478.1	Ssa3p
NP_009479.1	Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron
NP_009481.1	Rps8ap
NP_878044.1	Ybl071c-bp
NP_660100.1	Zn-ribbon electron carrier protein, required with Dph1p, Dph2p, Jjj3p, and Dph5p for synthesis of diphthamide, a modified histidine residue on Eft1p or Eft2p; required, with Elongator complex, for modification of wobble nucleosides in tRNA
NP_009484.2	Peripheral membrane protein that interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane, possibly by influencing its incorporation into lipid rafts
NP_009485.2	Prs4p
NP_009486.2	Ubp13p
NP_009487.2	Sef1p
NP_009489.1	Prx1p
NP_009490.1	Kip1p
NP_009492.1	Skt5p
NP_009493.1	Yel1p
NP_031358.1	Ybl059c-ap
NP_009494.1	Ybl059wp
NP_009495.1	UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate
NP_009496.1	Pth2p
NP_009497.1	Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation
NP_009498.1	Ybl055cp
NP_009499.1	Ybl054wp
NP_009501.1	Sas3p
NP_009502.1	Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage
NP_009503.1	Sec17p
NP_009504.1	Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase
NP_009506.1	Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins
NP_009507.1	Putative regulatory subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and a third subunit Psy2p; required for cisplatin resistance; GFP-fusion protein localizes to the nucleus
NP_009508.1	Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain
NP_009509.1	Ybl044wp
NP_009510.1	Non-essential protein of unknown function
NP_009511.1	High affinity uridine permease, localized to the plasma membrane; not involved in uracil transport
NP_009512.1	Pre7p
NP_009513.1	HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins
NP_878045.1	Ybl039w-bp
NP_009514.1	Ura7p
NP_009515.1	Mrpl16p
NP_009516.1	Apl3p
NP_009517.1	Ybl036cp
NP_009518.1	Pol12p
NP_009519.1	Stu1p
NP_009520.1	Rib1p
NP_009521.1	RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length
NP_009522.1	She1p
NP_009523.1	Pet9p
NP_076874.1	Ybl029c-ap
NP_009524.1	Ybl029wp
NP_009525.1	Ybl028cp
NP_009526.1	Rpl19bp
NP_009527.1	Lsm2p
NP_009528.1	Rrn10p
NP_009529.1	S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120
NP_009530.1	Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
NP_009531.1	Pim1p
NP_009532.1	Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding
NP_009533.1	Rft1p
NP_009534.1	Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII
NP_009535.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
NP_009536.1	Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments
NP_009537.1	Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation
NP_009538.1	Ach1p
NP_009539.1	Rrn6p
NP_009540.2	Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate
NP_009542.1	Sct1p
NP_009543.1	Ybl010cp
NP_009544.1	Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins
NP_878046.1	Ybl008w-ap
NP_009545.1	Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3 and H4 genes; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores
NP_009546.1	Sla1p
NP_009547.2	Ldb7p
NP_009548.1	Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)
NP_009549.1	Ybl005w-bp
NP_009550.1	Ybl005w-ap
NP_009551.2	Utp20p
NP_009552.1	One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
NP_009553.1	One of two nearly identical (see HTB1) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
NP_009554.1	Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis
NP_009555.1	Putative neutral trehalase, required for thermotolerance and may mediate resistance to other cellular stresses
NP_009556.1	Rer2p
NP_009557.1	Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
NP_009558.1	Gpi18p
NP_009559.1	Rcr1p
NP_009560.1	Uga2p
NP_009561.1	Dsf2p
NP_009562.1	Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs
NP_009563.1	One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
NP_009564.1	One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation
NP_009565.1	Ipp1p
NP_009567.1	Ybr012w-bp
NP_009568.1	Ybr012w-ap
NP_009569.1	Ybr013cp
NP_009570.1	Monothiol glutaredoxin; more similar in activity to dithiol than other monothiol glutaredoxins; membrane localized; forms homodimers; does not bind metal ions
NP_009571.1	Mnn2p
NP_009572.1	Ybr016wp
NP_009573.1	Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous nuclear ribonucleoproteins to the nucleoplasm, binds rg-nuclear localization signals on Nab2p and Hrp1p, plays a role in cell-cycle progression
NP_009574.1	Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism
NP_009575.1	UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers
NP_009576.1	Galactokinase, phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p
NP_009577.1	Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues
NP_009578.1	Poa1p
NP_009579.1	Chs3p
NP_009580.1	Sco2p
NP_009581.1	P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; protein levels are induced by hydrogen peroxide
NP_009582.1	Etr1p
NP_009584.1	Ybr028cp
NP_009585.1	Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids
NP_009586.1	Ybr030wp
NP_009587.1	Rpl4ap
NP_009589.1	Putative zinc cluster protein; YBR033W is not an essential gene
NP_009590.1	Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants
NP_009591.1	Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism
NP_009592.1	Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations
NP_009593.1	Sco1p
NP_009594.1	Chs2p
NP_009595.1	Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
NP_009596.1	Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating
NP_009597.2	Fatty acid transporter and very long-chain fatty acyl-CoA synthetase, may form a complex with Faa1p or Faa4p that imports and activates exogenous fatty acids
NP_009598.1	Protein of unknown function, affects chromosome stability when overexpressed
NP_009599.1	Qdr3p
NP_009600.1	Tcm62p
NP_009601.1	Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p
NP_009602.1	Zta1p
NP_009603.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_009604.1	Rps11bp
NP_009605.1	Reb1p
NP_009606.1	Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease
NP_009608.1	Rfs1p
NP_009609.1	Ybr053cp
NP_009610.1	Yro2p
NP_009611.1	Splicing factor, component of the U4/U6-U5 snRNP complex
NP_009612.1	Ybr056wp
NP_009613.1	Mum2p
NP_009614.2	Ubp14p
NP_116327.1	Tsc3p
NP_009615.1	Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization
NP_009616.1	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p
NP_009617.1	Trm7p
NP_009619.1	Ybr063cp
NP_009621.1	Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p
NP_009622.1	Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p
NP_009623.1	Tip1p
NP_009624.1	High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains
NP_009625.1	Tat1p
NP_009626.1	Component of UDP-GlcNAc transferase required for the second step of dolichyl-linked oligosaccharide synthesis; anchors the catalytic subunit Alg13p to the ER membrane; similar to bacterial and human glycosyltransferases
NP_009627.1	Ybr071wp
NP_009628.1	Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; oligomer activation requires a heat-induced conformational change; not expressed in unstressed cells
NP_878048.1	Ybr072c-ap
NP_009629.2	Rdh54p
NP_009630.2	Ybr074wp
NP_009632.1	Non-essential protein of unknown function
NP_009633.1	Slm4p
NP_009634.1	GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p
NP_009635.1	Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes
NP_009636.1	Sec18p
NP_009637.1	Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex
NP_009638.1	Ubiquitin-conjugating enzyme (E2), mediates degradation of short-lived and abnormal proteins; interacts with E3-CaM in ubiquitinating calmodulin; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response
NP_009639.1	Transcription factor required for full Ty1 epxression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member
NP_009640.1	Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase
NP_009641.1	Rpl19ap
NP_009642.1	Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Pet9p and Aac1p; has roles in maintenance of viability and in respiration
NP_061491.1	Ybr085c-ap
NP_009643.2	Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process
NP_009644.1	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
NP_009645.1	Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair
NP_009647.1	Nhp6bp
NP_009648.1	Ybr090cp
NP_009649.1	Mrs5p
NP_009650.1	Pho3p
NP_009651.1	Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2
NP_009652.1	Putative tubulin tyrosine ligase associated with P-bodies
NP_009653.2	Subunit of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth
NP_009654.1	Ybr096wp
NP_009655.1	Vps15p
NP_009656.2	Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination and DNA repair
NP_009659.1	Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum
NP_009660.1	Exo84p
NP_009661.1	WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus
NP_009662.1	Ymc2p
NP_009663.1	Vid24p
NP_009664.1	Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
NP_009665.1	Protein with a role in kinetochore function, localizes to the outer kinetochore in a Ctf19p-dependent manner, interacts with Chl4p and Ctf19p
NP_009666.2	Protein interacting with Rsv167p; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_009667.1	Cmd1p
NP_009668.1	Mannosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog
NP_009669.1	Ysa1p
NP_878049.2	Sus1p
NP_009670.1	General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
NP_009672.1	Rad16p
NP_009673.1	Lys2p
NP_009675.1	Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
NP_009676.1	Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes
NP_009677.1	U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing
NP_009678.1	Mitochondrial translational activator of the COB mRNA; phosphorylated
NP_009679.1	Grs1p
NP_009680.2	Mrpl36p
NP_009681.1	Tfc1p
NP_009683.1	Ptc4p
NP_009684.1	Tps1p
NP_009685.1	Vma2p
NP_009686.1	Subunit of an autophagy-specific phosphatidylinositol 3-kinase complex (with Vps34p, Vps15p, and Vps30p) required for organization of a pre-autophagosomal structure; ATG14 transcription is activated by Gln3p during nitrogen starvation
NP_009687.1	Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_009688.1	She3p
NP_009689.1	Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway
NP_009690.1	High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease
NP_009691.1	Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p
NP_009693.1	Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters
NP_009694.1	Mec1p
NP_009695.1	Ybr137wp
NP_009696.1	Ybr138cp
NP_009697.1	Ybr139wp
NP_009698.1	Ira1p
NP_009699.1	Ybr141cp
NP_009700.1	Mak5p
NP_009701.1	Sup45p
NP_009703.1	Alcohol dehydrogenase isoenzyme V; involved in ethanol production
NP_009704.1	Mrps9p
NP_009705.1	Ybr147wp
NP_009706.1	Ysw1p
NP_009707.1	NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; purified as homodimer; naturally occurs with a N-terminus degradation product
NP_009708.1	Tbs1p
NP_009709.1	Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus
NP_009710.1	mRNA splicing factor, component of U4/U6.U5 tri-snRNP; interacts genetically and physically with Prp38p
NP_009711.1	Rib7p
NP_009712.1	Rpb5p
NP_009713.1	TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion
NP_009714.1	Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase
NP_009715.2	Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization
NP_009716.1	Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
NP_009717.1	Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides
NP_009718.1	Cdc28p
NP_009719.1	Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p
NP_009720.1	Tos1p
NP_009721.1	Ysy6p
NP_009722.1	Protein of unknown function, shows similarity to RNA-processing protein Pta1p
NP_009723.1	Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor
NP_009724.1	Ubs1p
NP_009725.1	Tyr1p
NP_009726.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
NP_009727.1	Pex32p
NP_009728.1	Sse2p
NP_009729.1	Npl4p
NP_009730.1	Sec66p
NP_009731.2	Smy2p
NP_009732.1	Ump1p
NP_009734.1	Swd3p
NP_009735.1	Ketopantoate hydroxymethyltransferase, required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate
NP_009736.1	Eht1p
NP_009738.1	Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain
NP_009739.1	Putative dityrosine transporter, required for spore wall synthesis; expressed during sporulation; member of the major facilitator superfamily (DHA1 family) of multidrug resistance transporters
NP_009740.1	Rps6bp
NP_009741.1	Smp1p
NP_878050.1	Ybr182c-ap
NP_009742.1	Ypc1p
NP_009743.1	Ybr184wp
NP_009744.1	Protein involved in assembly of mitochondrial respiratory complexes; may act as a receptor for proteins destined for export from the mitochondrial matrix to the inner membrane
NP_009745.2	Pch2p
NP_009746.1	Putative protein of unknown function; expression is reduced in a gcr1 null mutant; GFP-fusion protein localizes to the vacuole; expression pattern and physical interactions suggest a possible role in ribosome biogenesis
NP_009747.1	Ntc20p
NP_009748.1	Rps9bp
NP_009750.1	Rpl21ap
NP_009751.1	Rim2p
NP_009752.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_009753.1	Protein proposed to be associated with the nuclear pore complex; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and a severe growth defect in minimal glycerol media
NP_009754.1	Subunit of chromatin assembly factor I (CAF-1), negative regulator of the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46
NP_009755.1	Pgi1p
NP_878051.1	Ybr196c-ap
NP_878052.1	Ybr196c-bp
NP_009756.1	Ybr197cp
NP_009757.1	Taf5p
NP_009758.1	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
NP_009759.1	Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p
NP_878053.1	Ybr200w-ap
NP_009760.1	Endoplasmic reticulum membrane protein, required for ER-associated protein degradation of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p
NP_001032571.1	Ybr201c-ap
NP_009761.1	Mcm7p
NP_009762.1	Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_009763.1	Ybr204cp
NP_009764.1	Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
NP_009766.1	Putative high affinity iron transporter involved in transport of intravacuolar stores of iron; forms complex with Fet5p; expression is regulated by iron; proposed to play indirect role in endocytosis
NP_009767.1	Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
NP_009769.1	Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p
NP_009770.1	Essential kinetochore protein associated with microtubules and spindle pole bodies; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance
NP_009771.1	RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; expressed in stationary phase
NP_009772.1	Met8p
NP_009773.1	Sds24p
NP_009774.2	Hpc2p
NP_009775.1	Ybp1p
NP_009776.1	Ubiquitin-like modifier, conjugated via an isopeptide bond to a lysine residue of Atg5p by the E1 enzyme, Atg7p, and the E2 enzyme, Atg10p, a step that is essential for autophagy
NP_009777.1	Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis
NP_009778.1	Ybr219cp
NP_009779.1	Ybr220cp
NP_009780.1	Pdb1p
NP_878054.1	Ybr221w-ap
NP_009781.1	Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase
NP_009782.1	Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3'-phosphotyrosyl bonds to generate 3'-phosphate DNA and tyrosine, involved in the repair of DNA lesions created by topoisomerase I
NP_009784.1	Ybr225wp
NP_009786.1	Mitochondrial ATP-binding protein, possibly a mitochondrial chaperone with non-proteolytic function; similar to bacterial ClpX proteins
NP_009787.1	Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p
NP_009788.1	Rot2p
NP_009789.1	Om14p
NP_001018029.1	Ybr230w-ap
NP_009790.1	Swc5p
NP_009792.1	RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length
NP_631876.1	Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis
NP_009793.1	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
NP_009794.1	Ybr235wp
NP_009795.1	Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA
NP_009796.1	RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
NP_009797.1	Ybr238cp
NP_009798.1	Ybr239cp
NP_009799.1	Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes
NP_009800.1	Ybr241cp
NP_009801.1	Ybr242wp
NP_009802.1	UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin
NP_009803.1	Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
NP_009804.1	Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation
NP_009805.1	Ybr246wp
NP_009806.1	Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus
NP_009807.1	Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor
NP_009808.1	Aro4p
NP_009809.1	Spo23p
NP_009810.1	Mrps5p
NP_009811.1	dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability
NP_009812.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_009813.1	Trs20p
NP_009814.1	Ybr255wp
NP_116328.2	Ybr255c-ap
NP_009815.1	Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway
NP_009816.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P
NP_009817.1	Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres
NP_009818.1	Ybr259wp
NP_009819.1	Rgd1p
NP_009820.1	Ybr261cp
NP_009821.1	Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media
NP_009822.2	Shm1p
NP_009823.2	Ypt10p
NP_009824.1	Tsc10p
NP_009825.1	Rei1p
NP_009827.1	Mrpl37p
NP_009828.2	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_009830.1	Ybr271wp
NP_009831.1	Protein of unknown function, involved in DNA mismatch repair during slow growth; has weak similarity to Msh1p
NP_009832.1	Ubx7p
NP_009833.1	Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase
NP_009834.1	Rif1p
NP_009835.1	Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle
NP_009837.1	Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle
NP_009838.1	RNAP II-associated protein; defines large complex biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme; required for full expression of a subset of cell cycle-regulated genes; homolog of human PD2/hPAF1
NP_009839.2	Saf1p
NP_009840.1	Probable di- and tri-peptidase; forms a complex with Dug1p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)
NP_009841.1	Mrpl27p
NP_009842.1	Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential
NP_009843.1	Ybr284wp
NP_009844.1	Ybr285wp
NP_009845.2	Vacuolar aminopeptidase Y, processed to mature form by Prb1p
NP_009846.1	Ybr287wp
NP_009847.1	Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway
NP_009848.1	Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p
NP_009849.1	Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification
NP_009850.1	Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family
NP_009852.1	Vba2p
NP_009853.1	Sul1p
NP_009854.1	Pca1p
NP_009855.1	Pho89p
NP_878055.1	Ybr296c-ap
NP_009856.1	Mal33p
NP_009857.1	Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL3 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; functional in genomic reference strain S288C
NP_878056.1	Ybr298c-ap
NP_009858.1	Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL3 complex locus; functional in genomic reference strain S288C
NP_009860.1	Dan3p
NP_009861.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_009863.2	Ycl073cp
NP_009864.1	Vba3p
NP_009865.2	Ycl068cp
NP_009866.1	Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression
NP_009867.1	Silenced copy of ALPHA1 at HML, encoding a transcriptional coactivator involved in the regulation of mating-type alpha-specific gene expression
NP_001018030.1	Cha1p
NP_009870.1	Vac17p
NP_009871.2	S-phase checkpoint protein found at replication forks, required for DNA replication; also required for Rad53p activation during DNA replication stress, where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p
NP_009872.1	Krr1p
NP_001018031.2	Ycl058w-ap
NP_065435.1	Ycl057c-ap
NP_009874.1	Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins
NP_009875.1	Ycl056cp
NP_009876.1	Transcription factor required for gene regulation in repsonse to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone
NP_009877.1	Spb1p
NP_009878.1	Pbn1p
NP_009879.2	Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes
NP_009880.2	Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p
NP_009881.2	Ycl049cp
NP_001032573.1	Ycl048w-ap
NP_009882.1	Sps22p
NP_009883.1	Ycl047cp
NP_009884.1	Ycl045cp
NP_009886.1	Subunit, with Yme1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; required for growth of cells lacking the mitochondrial genome
NP_009887.1	Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds
NP_009889.2	Ycl042wp
NP_009890.1	Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources
NP_009891.1	Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions
NP_009892.1	Protein required for the breakdown of autophagic vesicles in the vacuole during autophagy, putative integral membrane protein that localizes to vacuolar membranes and punctate structures attached to the vacuole
NP_009893.2	Sro9p
NP_009894.1	Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation
NP_009895.1	Hydroperoxide and superoxide-radical responsive heat-stable glutathione-dependent disulfide oxidoreductase with active site cysteine pair; protects cells from oxidative damage
NP_009896.2	Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
NP_009897.1	Ycl033cp
NP_009898.1	Ste50p
NP_009899.1	Rrp7p
NP_009900.2	Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis
NP_009901.1	Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170
NP_009902.2	[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
NP_009903.2	Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate
NP_065436.1	Putative protein of unknown function; similar to bacterial nitroreductases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
NP_009904.2	Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis; similar to bacterial nitroreductases
NP_009905.3	Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
NP_009907.2	Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
NP_065437.1	Ycl021w-ap
NP_009909.2	Ycl019wp
NP_009910.2	Ycl020wp
NP_009911.2	Leu2p
NP_009912.2	Nfs1p
NP_009913.2	Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance
NP_009914.2	Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding
NP_976246.1	Ycl012cp
NP_009916.1	Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro
NP_009917.1	Sgf29p
NP_009918.1	Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria
NP_009919.3	Stp22p
NP_958835.1	Vma9p
NP_009922.2	Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria
NP_009923.2	Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis
NP_009924.3	Ycl002cp
NP_009925.1	Rer1p
NP_009926.1	Ycl001w-ap
NP_076878.1	Ycl001w-bp
NP_009928.1	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
NP_009929.1	Mrpl32p
NP_009930.1	Ycp4p
NP_009931.1	Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors
NP_009933.1	Ycr007cp
NP_009934.1	Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p
NP_009935.1	Rvs161p
NP_009936.1	Ady2p
NP_009937.2	Putative ATP-dependent permease of the ABC transporter family of proteins
NP_009938.2	Pgk1p
NP_009940.2	Pol4p
NP_009941.2	Ycr015cp
NP_009942.2	Ycr016wp
NP_009943.2	Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion
NP_009944.2	Srd1p
NP_009946.1	Protein necessary for structural stability of L-A double-stranded RNA-containing particles
NP_009947.1	Protein required for respiratory growth and stability of the mitochondrial genome
NP_009948.1	Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family
NP_009949.1	Htl1p
NP_009950.1	Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase
NP_009952.2	Ycr023cp
NP_009953.1	Slm5p
NP_878057.1	Ycr024c-bp
NP_058137.1	Small single-membrane span proteolipid that functions as a regulatory subunit of the plasma membrane H(+)-ATPase Pma1p, forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines
NP_009955.2	Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation
NP_009956.2	Rhb1p
NP_009957.1	Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph
NP_009958.2	Single-stranded DNA-binding protein essential for mitochondrial genome maintenance; involved in mitochondrial DNA replication
NP_009959.2	Syp1p
NP_009960.2	Rps14ap
NP_009961.2	PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins, which are implicated in disease syndromes due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting
NP_009962.2	Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein
NP_009963.1	Fen1p
NP_009964.2	Rrp43p
NP_009965.2	Rbk1p
NP_009966.2	Pho87p
NP_009967.2	GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types
NP_009868.3	Matalpha2p
NP_009869.3	Transcriptional co-activator involved in regulation of mating-type-specific gene expression; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the MATalpha mating type cassette
NP_009971.1	Taf2p
NP_009972.1	Ycr043cp
NP_009973.1	Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1
NP_009974.1	Ycr045cp
NP_009975.1	Mitochondrial ribosomal protein of the large subunit, required for respiration and for maintenance of the mitochondrial genome
NP_009976.1	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_009978.1	Are1p
NP_009979.1	Ycr050cp
NP_009980.1	Ycr051wp
NP_009981.1	Rsc6p
NP_009982.1	Threonine synthase, conserved protein that catalyzes formation of threonine from 0-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway
NP_009983.1	Essential protein of unknown function; upstream region contains a Gcn4p responsive site suggesting a possible role in amino acid biosynthesis
NP_009984.1	Pwp2p
NP_009985.1	Yih1p
NP_009986.1	Tah1p
NP_009987.2	Ycr061wp
NP_009990.1	Protein involved in bud-site selection; analysis of integrated high-throughput datasets predicts an involvement in RNA splicing; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_009991.2	Hcm1p
NP_009992.1	Rad18p
NP_009993.1	Sed4p
NP_009994.2	Lipase, required for intravacuolar lysis of autophagic bodies; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway
NP_009995.1	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway
NP_009996.2	Mitochondrial ribosomal protein of the small subunit
NP_009997.2	WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus
NP_009998.2	Ssk22p
NP_009999.2	Sol2p
NP_010000.1	Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains
NP_878058.1	Ycr075w-ap
NP_010001.1	Ycr076cp
NP_010002.2	Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p
NP_010003.2	Ptc6p
NP_010004.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression
NP_010005.1	Protein of unknown function, putative transcriptional regulator; proposed to be a Ada Histone acetyltransferase complex component; GFP tagged protein is localized to the cytoplasm and nucleus
NP_010006.1	Trx3p
NP_010007.1	Tup1p
NP_010009.1	Nucleolar protein that forms a complex with Lrs4p which binds Mam1p at kinetochores during meiosis I to mediate accurate chromosome segregation, may be involved in premeiotic DNA replication; possible role in telomere maintenance
NP_010011.1	Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene
NP_010012.1	Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization
NP_010013.2	Fig2p
NP_010014.1	Ycr090cp
NP_010015.2	Putative serine/threonine protein kinase, most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily
NP_010016.2	Msh3p
NP_010017.2	Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
NP_010018.1	Endosomal protein that regulates cell polarity, controls polarized growth; similar to Ynr048wp and Lem3p
NP_010019.1	Oca4p
NP_001018032.1	Ycr095w-ap
NP_010020.1	Silenced copy of a2 at HMR; similarity to Alpha2p; required along with a1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system
NP_010021.1	Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells
NP_010022.1	Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability
NP_010023.1	Ycr099cp
NP_010024.1	Ycr100cp
NP_010025.1	Ycr101cp
NP_010026.1	Ycr102cp
NP_010029.1	Pau3p
NP_010030.1	NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance
NP_010031.1	Zinc cluster transcription factor involved in conferring resistance to cycloheximide
NP_010032.1	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
NP_878059.1	Ycr108cp
NP_010033.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_010034.1	Mph2p
NP_010035.1	Sor2p
NP_010036.1	Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose
NP_010037.1	Thi13p
NP_010038.1	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response
NP_010040.1	Ydl241wp
NP_010041.1	Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis
NP_010042.1	Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p
NP_010043.1	Gud1p
NP_010044.1	Putative protein of unknown function; YDL237W is not an essential gene; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_010045.1	Pho13p
NP_010046.1	Ypd1p
NP_010047.1	Gyp7p
NP_010048.1	Ydl233wp
NP_010049.1	Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex
NP_010050.1	Zinc finger protein containing five transmembrane domains; null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport
NP_010051.1	Ptp1p
NP_010052.1	Ssb1p
NP_010054.1	Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p
NP_010055.1	Gcs1p
NP_010056.1	Shs1p
NP_010057.1	Whi4p
NP_010058.1	Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis
NP_010059.1	Integral membrane protein localized to mitochondria (untagged protein) and eisosomes, immobile patches at the cortex associated with endocytosis; sporulation and sphingolipid content are altered in mutants; has homologs SUR7 and YNL194C
NP_010061.1	Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication through recruitment of specific sub-complexes, but the essential function is telomere capping
NP_010062.1	Dtd1p
NP_010063.1	Ydl218wp
NP_010064.1	Tim22p
NP_010065.2	Rri1p
NP_010066.1	NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
NP_010067.1	Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor
NP_010068.1	Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes
NP_010069.1	Shr3p
NP_010070.1	Ydl211cp
NP_010071.1	Uga4p
NP_010072.1	Protein involved in pre-mRNA splicing, component of a complex containing Cef1p; interacts with Prp19p; contains an RNA recognition motif; has similarity to S. pombe Cwf2p
NP_010073.2	Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing
NP_010074.1	Gle1p
NP_010075.1	Ydl206wp
NP_010076.1	Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p
NP_010077.1	Rtn2p
NP_010078.1	Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in purified mitochondria
NP_010079.1	Mrpl11p
NP_010080.1	Trm8p
NP_010081.2	Mgt1p
NP_010082.1	Ydl199cp
NP_010083.1	Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family
NP_010084.1	Asf2p
NP_010086.1	Sec31p
NP_010087.1	Snf3p
NP_010088.1	Prenyltransferase, required for cell viability; involved in protein trafficking
NP_010089.1	Arf1p
NP_010090.1	Rpl35ap
NP_010091.1	Ufd2p
NP_010092.2	Rbs1p
NP_010093.1	Pph22p
NP_010095.1	Ydl186wp
NP_010096.1	Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease
NP_010097.1	Rpl41ap
NP_010098.1	Ydl183cp
NP_010099.1	Lys20p
NP_010100.1	Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase, inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has similarity to Stf1p and both Inh1p and Stf1p exhibit the potential to form coiled-coil structures
NP_010101.1	Ydl180wp
NP_010102.1	Pcl9p
NP_010103.1	Dld2p
NP_010104.1	Ydl177cp
NP_010105.1	Ydl176wp
NP_010106.1	RING finger protein that interacts with the arginine methyltransferase Hmt1p; may regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air1p
NP_010107.1	Dld1p
NP_010108.1	Ydl173wp
NP_010110.1	NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source
NP_010111.1	Uga3p
NP_010112.1	Ugx2p
NP_010113.1	Sfa1p
NP_010114.1	Protein of unknown function, rich in asparagine residues
NP_010115.1	Fap7p
NP_010116.1	Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
NP_010117.1	DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination
NP_010120.1	Epsin-like protein involved in endocytosis and actin patch assembly and functionally redundant with Ent2p; binds clathrin via a clathrin-binding domain motif at C-terminus
NP_878060.1	Ydl160c-ap
NP_010121.1	Dhh1p
NP_076884.1	Ydl159w-ap
NP_010122.1	Ste7p
NP_010124.1	Ydl157cp
NP_010125.1	Ydl156wp
NP_010126.1	Clb3p
NP_010127.1	Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans
NP_010128.1	Sas10p
NP_010131.1	Rpc53p
NP_010132.1	Transmembrane protein involved in formation of Cvt and autophagic vesicles; cycles between the pre-autophagosomal structure and other cytosolic punctate structures, not found in autophagosomes
NP_010133.1	Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA
NP_010134.1	Rpn5p
NP_010135.1	Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface
NP_010136.1	Cop1p
NP_010137.2	Ydl144cp
NP_010138.1	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
NP_010139.1	Crd1p
NP_010140.1	Bpl1p
NP_010141.1	Rpo21p
NP_010142.2	Scm3p
NP_010143.1	Rgt2p
NP_010144.1	Arf2p
NP_010145.1	Rpl35bp
NP_010146.1	Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p
NP_010147.1	Pph21p
NP_010148.1	Rpl41bp
NP_010149.1	Ydl133wp
NP_010150.1	Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation
NP_010151.1	Lys21p
NP_010152.1	Stf1p
NP_010153.1	Rpp1bp
NP_010154.1	Ydl129wp
NP_010155.1	Vcx1p
NP_010156.2	Pcl2p
NP_010157.1	Cdc48p
NP_010158.1	Hnt1p
NP_010159.1	Ydl124wp
NP_010160.1	Sna4p
NP_010161.1	Ubp1p
NP_010162.1	Ydl121cp
NP_010163.1	Yfh1p
NP_010164.1	Ydl119cp
NP_010165.1	Ydl118wp
NP_010166.1	SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype and genetic interactions suggest a role in cytokinesis
NP_010167.1	Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis
NP_010168.4	Protein of unknown function, deletion causes hypersensitivity to the K1 killer toxin
NP_010169.1	Ydl114wp
NP_010170.1	Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm-to-vacuole targeting pathway; binds phosphatidylinositol-3-phosphate, involved in localization of membranes to the preautophagosome, potential Cdc28p substrate
NP_010171.1	Trm3p
NP_010172.1	Rrp42p
NP_010173.1	Tma17p
NP_010174.1	Ydl109cp
NP_010175.1	Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters
NP_010176.1	Peripherally bound inner membrane protein of the mitochondrial matrix involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p
NP_010177.1	Pho2p
NP_010178.1	Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex
NP_010179.1	Qri7p
NP_010180.1	UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis
NP_010181.1	Pol3p
NP_010182.1	Dun1p
NP_010183.1	Get3p
NP_010184.1	Cis-golgi localized protein involved in ER to Golgi transport; forms a complex with the mammalian GRASP65 homolog, Grh1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes
NP_010185.1	Snu23p
NP_010186.1	Rpn6p
NP_010188.1	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals
NP_010190.1	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt3p, can instead interact with Pmt2p in some conditions; target for new antifungals
NP_010191.1	Srp14p
NP_010192.1	Ubx3p
NP_010193.1	Ram1p
NP_010194.1	Ydl089wp
NP_010195.1	Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p
NP_010196.1	Luc7p
NP_010197.1	Ydl086wp
NP_075208.1	Ydl085c-ap
NP_010198.1	Nde2p
NP_010199.1	Sub2p
NP_010200.1	Rps16bp
NP_010201.1	Rpl13ap
NP_010202.1	Rpp1ap
NP_010203.1	Thi3p
NP_010204.1	Mrk1p
NP_010205.1	Peroxisomal malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle
NP_010206.1	Vam6p
NP_010207.1	Subunit of the RPD3L complex; involved in histone deacetylation
NP_010208.1	Rpl31ap
NP_010209.1	E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain
NP_010210.1	Ydl073wp
NP_010211.1	Yet3p
NP_010213.1	Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p
NP_010214.2	Mitochondrial translational activator of the COB mRNA; membrane protein that interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader
NP_010216.1	Subunit VIIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
NP_010217.1	Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes
NP_010218.2	Pex19p
NP_010219.1	Ubc9p
NP_010220.1	Ydl063cp
NP_010222.1	Rps29bp
NP_010223.1	Tsr1p
NP_010224.1	Rad59p
NP_010225.1	Uso1p
NP_010226.1	Ydl057wp
NP_010227.1	Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes
NP_010228.1	Psa1p
NP_010229.1	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
NP_010230.1	Pbp4p
NP_010231.1	Slc1p
NP_010232.1	RNA binding protein required for maturation of tRNA and snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen
NP_010234.1	Protein with similarity to Kre9p, which is involved in cell wall beta 1,6-glucan synthesis; overproduction suppresses growth defects of a kre9 null mutant
NP_010235.1	Stp4p
NP_010236.1	Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
NP_010237.1	Npc2p
NP_010238.1	Mrp10p
NP_010239.1	Flavin adenine dinucleotide (FAD) synthetase, performs the second step in synthesis of FAD from riboflavin
NP_010240.1	Mtf2p
NP_010241.1	Subunit of the SF3a splicing factor complex, required for spliceosome assembly
NP_010242.1	Sir2p
NP_010244.1	Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
NP_010245.1	Prm7p
NP_010246.1	Ydl038cp
NP_010247.1	Protein of unconfirmed function, similar to cell surface flocculin Muc1p; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
NP_010248.1	Pus9p
NP_010249.1	Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis
NP_010251.1	tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)
NP_010253.1	Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis
NP_010254.1	Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex
NP_010255.1	Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity
NP_010256.1	Mps1p
NP_010257.1	Ydl027cp
NP_010259.1	Ydl025cp
NP_010260.1	Protein of unknown function, involved in invasive and pseudohyphal growth
NP_010262.1	NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
NP_010263.1	Homolog of Gpm1p phosphoglycerate mutase which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event
NP_010264.1	Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses
NP_010265.1	Osh2p
NP_010266.1	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport
NP_010267.1	DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression
NP_010269.1	Tsc13p
NP_010270.1	Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin
NP_010271.1	Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate
NP_010272.1	Ydl012cp
NP_010274.1	Monothiol glutaredoxin that binds an iron-sulfur cluster; more similar in activity to dithiol than other monothiol glutaredoxins; forms homodimers; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
NP_010276.1	Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_001032574.1	Ydl007c-ap
NP_010277.1	Rpt2p
NP_010278.1	Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation
NP_010279.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_010280.1	Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
NP_010281.1	Mcd1p
NP_010282.1	Protein related to mammalian high mobility group proteins; likely component of the INO80 complex, which is an ATP-dependent chromatin-remodeling complex
NP_010283.1	Rmd1p
NP_010284.1	Nth1p
NP_010285.1	Yrb1p
NP_010286.1	Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane; similar to Rcr1p
NP_878061.1	Ydr003w-ap
NP_010287.1	Rad57p
NP_010288.1	Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB
NP_010289.1	Sok1p
NP_010290.1	Trp1p
NP_010292.1	Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity
NP_010294.1	Snq2p
NP_010295.1	Rpl4bp
NP_010296.1	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
NP_010297.1	Rad61p
NP_001035220.1	Meiosis-specific protein that down-regulates Rad51p-mediated mitotic recombination when the meiotic recombination machinery is impaired; early meiotic gene, transcribed specifically during meiotic prophase
NP_010299.1	Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis
NP_010300.1	Kcs1p
NP_010301.1	Ydr018cp
NP_010302.1	T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm
NP_010303.1	Predicted protein shares weak similarity with uridine kinases and with phosphoribokinases; null mutant suppresses dst1delta sensitivity for 6-azauracil
NP_010304.1	Nucleolar protein required for maturation of 18S rRNA, member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases
NP_010305.1	Protein required for autophagosome formation in concert with Atg17p; may be involved in microtubule organization; high-copy suppressor of CIK1 deletion
NP_010306.1	Ses1p
NP_010308.1	Rps11ap
NP_010309.1	Ydr026cp
NP_010310.1	Vps54p
NP_010311.1	Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes
NP_010313.1	Rad28p
NP_010314.2	Mitochondrial intermembrane space cysteine motif protein of 14 kDa
NP_010315.1	Pst2p
NP_010316.1	Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
NP_010317.1	Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer
NP_058138.1	Ydr034c-dp
NP_058139.1	Ydr034c-cp
NP_010318.1	Ydr034c-ap
NP_010319.1	Ydr034w-bp
NP_010320.1	Aro3p
NP_010321.1	Ehd3p
NP_010322.1	Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
NP_010323.1	Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family
NP_010324.1	P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux
NP_010325.1	P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
NP_010326.1	Rsm10p
NP_010327.1	Ydr042cp
NP_010328.1	Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response
NP_010329.1	Hem13p
NP_010330.1	Rpc11p
NP_010331.1	Bap3p
NP_010332.1	Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents
NP_010334.1	Zinc finger protein; putative transcription factor that may interact with proteins involved in histone acetylation or deacetylation; may be involved in altering acetylation on histone lysines
NP_010335.1	Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region
NP_010336.1	Ydr051cp
NP_010337.1	Regulatory subunit of Cdc7p-Dbf4p kinase complex, required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated
NP_010339.1	Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation
NP_010340.1	Pst1p
NP_010341.1	Ydr056cp
NP_010342.1	Yos9p
NP_010343.1	Tgl2p
NP_010344.1	Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins, central component of the cellular stress response; expression is heat inducible
NP_010345.1	Mak21p
NP_010346.1	Ydr061wp
NP_010347.1	Lcb2p
NP_010348.1	Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and displays decreased frequency of mitochondrial genome loss (petite formation)
NP_010349.1	Rps13p
NP_010350.1	Ydr065wp
NP_010351.1	Rtr2p
NP_010352.1	Oca6p
NP_010353.1	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
NP_010354.1	Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole
NP_010355.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_010356.1	Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication
NP_010357.1	Ipt1p
NP_010358.1	Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p
NP_010359.1	Tps2p
NP_010360.1	Pph3p
NP_010361.1	Rad55p
NP_010362.1	Sed1p
NP_010363.1	Shu2p
NP_010364.1	Pet100p
NP_076886.1	Tfb5p
NP_010365.1	Vps41p
NP_010366.1	Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes
NP_010367.1	Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping
NP_010368.3	Rrp8p
NP_010369.1	Tvp23p
NP_010370.1	Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p
NP_010371.1	Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p
NP_010372.1	Rrp1p
NP_010373.1	Slu7p
NP_010374.1	Ydr089wp
NP_010375.1	Ydr090cp
NP_010376.1	Rli1p
NP_010377.1	Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus
NP_010378.1	Dnf2p
NP_010381.1	JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1
NP_010382.1	Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p
NP_010383.1	Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
NP_058140.1	Ydr098c-bp
NP_058141.1	Ydr098c-ap
NP_010384.1	Bmh2p
NP_010385.1	Tvp15p
NP_010386.1	Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex
NP_010388.1	Ste5p
NP_010389.1	Spo71p
NP_010390.1	Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance
NP_010391.1	Component of the dynactin complex, localized to the pointed end of the Arp1p filament; may regulate membrane association of the complex
NP_010392.1	Tmn2p
NP_010393.1	Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication
NP_010394.1	Ydr109cp
NP_010395.1	Nucleolar protein required for DNA replication fork blocking and recombinational hotspot activities; binds to the replication fork barrier site in the rDNA region; related to retroviral integrases
NP_010396.1	Putative alanine transaminase (glutamic pyruvic transaminase)
NP_010398.1	Securin that inhibits anaphase by binding separin Esp1p, also blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also present in meiotic nuclei
NP_010399.1	Ydr114cp
NP_010400.1	Ydr115wp
NP_010401.1	Mrpl1p
NP_010402.1	Tma64p
NP_010403.1	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_010404.1	Ydr119wp
NP_001032575.1	Ydr119w-ap
NP_010405.1	tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments
NP_010406.1	Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing
NP_010407.1	Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p
NP_010408.1	Ino2p
NP_010409.1	Ydr124wp
NP_010410.1	Protein of unknown function, similar to Rlp24p
NP_010411.1	Swf1p
NP_010412.1	Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
NP_010413.1	Ydr128wp
NP_010414.1	Sac6p
NP_010415.1	Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent
NP_010416.1	Ydr131cp
NP_010417.1	Ydr132cp
NP_010419.1	Ycf1p
NP_010421.1	Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p
NP_010422.1	Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p
NP_010423.2	Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)
NP_010424.1	S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; methylates release factor eRF1 (Sup45p) in vitro; is not an essential gene; similar to E.coli PrmC
NP_010425.1	Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_010426.1	Pex7p
NP_010427.1	Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins
NP_010428.1	Mkc7p
NP_010429.1	Taf12p
NP_010430.1	Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
NP_010431.1	Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway
NP_010432.1	Kgd2p
NP_010434.1	Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex
NP_010435.1	Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis
NP_010436.1	Highly-acidic cytoplasmic RWD domain-containing protein of unknown function, sensitive to proteolysis, N-terminal region has high content of acidic amino acid residues, putative IUP (intrinsically unstructured protein)
NP_010437.1	Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin
NP_010439.1	Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A
NP_010440.1	Rpa14p
NP_010442.1	Hom2p
NP_010443.1	Sac3p
NP_010444.1	Ssy1p
NP_010445.1	Ydr161wp
NP_010446.1	Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p
NP_010447.1	Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has similarity to S. pombe Cwf15p
NP_010448.1	Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function
NP_010449.1	Trm82p
NP_010450.1	Sec5p
NP_010451.1	Taf10p
NP_010452.1	Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding
NP_010453.1	Stb3p
NP_878062.1	Ydr169c-ap
NP_010454.1	Sec7p
NP_010455.1	Ydr170w-ap
NP_010456.1	Small heat shock protein (sHSP) with chaperone activity; forms barrel-shaped oligomers that suppress unfolded protein aggregation; involved in cytoskeleton reorganization after heat shock
NP_010457.1	Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a dominant cytoplasmically inherited protein aggregate that alters translational fidelity and creates a nonsense suppressor phenotype
NP_010458.1	Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes
NP_010459.1	Hmo1p
NP_010460.1	Rsm24p
NP_010461.1	Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex
NP_010462.1	Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response
NP_010463.1	Sdh4p
NP_010464.1	Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling
NP_010465.2	Ydr179w-ap
NP_010466.1	Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX
NP_010467.1	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p
NP_010468.1	Putative membrane protein of unknown function involved in Mn2+ homeostasis; mutants display actin and general growth defects, heterogeneous cell cycle arrests, and pleiotropic defects in cell cycle progression and organelle distribution
NP_878063.1	Ydr182w-ap
NP_010469.1	Protein with a possible role in folding of beta-tubulin; has weak similarity to phosducins, which are G-protein regulators
NP_010470.1	Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern
NP_010471.1	Ydr185cp
NP_010472.1	Ydr186cp
NP_010474.1	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif
NP_010475.1	Sly1p
NP_010476.1	Rvb1p
NP_010477.1	Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
NP_010478.1	Subunit of the nuclear pore complex (NPC) that localizes exclusively to the cytoplasmic side; involved in RNA export, most likely at a terminal step; interacts with Gle1p
NP_010480.1	Mss116p
NP_878064.1	Ydr194w-ap
NP_010481.1	Ref2p
NP_010482.1	Ydr196cp
NP_010483.1	Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader
NP_010484.1	Rkm2p
NP_010486.1	Vps64p
NP_010487.1	Spc19p
NP_010488.1	Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme
NP_010490.1	Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex
NP_010491.2	Msc2p
NP_010492.1	Protein involved in inhibition of translation and nonsense-mediated decay; interacts with cap binding protein Cdc33p and with Nam7p; localizes to P-bodies upon glucose starvation; mRNA abundance regulated by mRNA decay factors
NP_010493.1	Ume6p
NP_010494.1	Phosphatidylinositol-4-phosphate 5-kinase, involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation
NP_010496.1	Ydr210wp
NP_058142.1	Ydr210w-bp
NP_058143.1	Ydr210w-ap
NP_620387.1	Ydr210c-dp
NP_620388.1	Ydr210c-cp
NP_010497.1	Gcd6p
NP_010498.1	Tcp1p
NP_010499.1	Upc2p
NP_010500.1	Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to Hch1p; expression is regulated by stresses such as heat shock
NP_010502.1	Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization
NP_010503.1	Rad9p
NP_010504.1	Spr28p
NP_010505.1	Mitochondria-associated F-box protein involved in maintenance of normal mitochondrial morphology; interacts with Skp1p through the F-box motif; preferentially localizes to the mother cell during budding
NP_010507.1	Gtb1p
NP_010508.1	Ydr222wp
NP_010509.1	Transcriptional corepressor involved in the regulation of ribosomal protein gene transcription via the TOR signaling pathway and protein kinase A, phosphorylated by activated Yak1p which promotes accumulation of Crf1p in the nucleus
NP_010510.1	One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
NP_010511.1	One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
NP_010512.1	Adk1p
NP_010513.1	Sir4p
NP_010514.1	mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA), involved in pre-mRNA 3' end processing and in transcription termination; binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)
NP_010515.1	Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the action of Vps33p and vice versa, localizes to the rim of the vacuole as cells approach stationary phase
NP_010517.1	Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase
NP_010518.1	Hem1p
NP_010519.1	Rtn1p
NP_010520.1	Lys4p
NP_010521.1	U1 snRNP protein involved in splicing, required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats
NP_010522.1	Riboflavin kinase, phosphorylates riboflavin to form riboflavin monophosphate (FMN), which is a necessary cofactor for many enzymes; localizes to microsomes and to the mitochondrial inner membrane
NP_010523.1	Mrpl7p
NP_010524.1	Sec26p
NP_010525.1	Ydr239cp
NP_010526.1	Snu56p
NP_010528.1	Putative amidase
NP_010529.1	RNA helicase in the DEAD-box family, involved in RNA isomerization at the 5' splice site
NP_010530.1	Pex5p
NP_010531.1	Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family
NP_010532.1	Trs23p
NP_878065.1	Ydr246w-ap
NP_010533.1	Vhs1p
NP_010534.1	Ydr248cp
NP_010535.1	Ydr249cp
NP_010537.1	Pam1p
NP_010538.1	Btt1p
NP_010539.1	Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p
NP_010540.1	Outer kinetochore protein required for chromosome stability, interacts with kinetochore proteins Ctf19p, Ctf3p, and Iml3p; exhibits a two-hybrid interaction with Mif2p; association with CEN DNA requires Ctf19p
NP_010541.1	Rmd5p
NP_010542.1	Cta1p
NP_010543.1	Set7p
NP_010544.1	Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; prevents the aggregation of misfolded matrix proteins; component of the mitochondrial proteolysis system
NP_010545.1	Yap6p
NP_010546.1	Swm1p
NP_010547.1	Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
NP_058146.1	Ydr261w-bp
NP_058147.1	Ydr261w-ap
NP_058148.1	Ydr261c-dp
NP_058149.1	Ydr261c-cp
NP_010548.1	Ydr262wp
NP_010549.1	Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination
NP_010550.1	Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats
NP_010551.1	Pex10p
NP_010552.1	Ydr266cp
NP_010553.1	Essential protein involved in assembly of cytosolic and nuclear iron-sulfur proteins
NP_010554.1	Msw1p
NP_010556.1	Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases
NP_010558.1	Glo2p
NP_010559.1	Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II
NP_010561.1	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
NP_010562.1	Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential
NP_010563.1	Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation
NP_010565.1	Rnh202p
NP_010566.1	Rrp45p
NP_010567.1	Protein of unknown function, expression is regulated by phosphate levels
NP_010568.1	Ydr282cp
NP_010569.1	Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex
NP_010570.1	Dpp1p
NP_010571.1	Zip1p
NP_010572.1	Ydr286cp
NP_010573.1	Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy
NP_010574.1	Nse3p
NP_010575.1	Rtt103p
NP_010577.1	Putative DNA helicase
NP_010578.1	Srp101p
NP_010579.1	Ssd1p
NP_010580.1	Dpl1p
NP_010581.1	Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex containing an Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance
NP_010582.1	Protein involved in homologous recombination in mitochondria and in transcription regulation in nucleus; binds to activation domains of acidic activators; required for recombination-dependent mtDNA partitioning
NP_010583.1	Sur2p
NP_010584.1	Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated
NP_010585.1	Essential protein possibly involved in secretion; multicopy suppressor of sensitivity to Brefeldin A
NP_010586.1	Pro1p
NP_010587.1	RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF
NP_010588.1	Gpi11p
NP_010589.1	Rsc3p
NP_010590.1	Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER
NP_010591.1	Hnt2p
NP_010592.1	Ydr306cp
NP_010593.1	Ydr307wp
NP_010594.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p
NP_010595.1	Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain
NP_010596.1	Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; involved in telomere maintenance, regulated by the pachytene checkpoint
NP_010597.1	Tfb1p
NP_010598.1	Ssf2p
NP_010599.1	RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain
NP_010600.1	Rad34p
NP_010601.1	Ipk1p
NP_010602.1	Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations
NP_058150.1	Ydr316w-bp
NP_058151.1	Ydr316w-ap
NP_010603.1	Protein of unknown function involved in DNA repair
NP_010604.2	Protein involved in minichromosome maintenance; component of the COMA complex (Ctf19p, Okp1p, Mcm21p, Ame1p) that bridges kinetochore subunits that are in contact with centromeric DNA and the subunits bound to microtubules
NP_010605.1	Yft2p
NP_010606.1	Swa2p
NP_710144.1	Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis
NP_010607.1	Cytosolic L-asparaginase, involved in asparagine catabolism
NP_010608.1	Mrpl35p
NP_010609.1	Tim11p
NP_010610.1	Pep7p
NP_010611.1	Utp4p
NP_010612.2	Ycg1p
NP_010613.1	Ysp2p
NP_010615.1	Skp1p
NP_010616.1	Pex3p
NP_010617.1	Ubx5p
NP_010618.1	Gpi8p
NP_010619.1	hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci
NP_010620.1	Ydr333cp
NP_010621.1	Swr1p
NP_010622.1	Msn5p
NP_010623.1	Ydr336wp
NP_010624.1	Mrps28p
NP_010626.1	Fcf1p
NP_010628.1	Ydr341cp
NP_010629.1	Hxt7p
NP_010630.1	Hxt6p
NP_010632.1	Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
NP_010633.1	Svf1p
NP_010634.1	Mrp1p
NP_010635.1	Ydr348cp
NP_010636.1	Yps7p
NP_010637.1	Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
NP_010638.1	Sbe2p
NP_010639.1	Ydr352wp
NP_010640.1	Trr1p
NP_010641.1	Trp4p
NP_010643.1	Spc110p
NP_010644.1	Ydr357cp
NP_010645.1	Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi
NP_010646.2	Eaf1p
NP_010648.1	Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport
NP_010649.1	Tfc6p
NP_010650.1	Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins
NP_010651.1	Sem1p
NP_010652.1	Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats
NP_010653.1	Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels
NP_058152.1	Ydr365w-bp
NP_058153.1	Ydr365w-ap
NP_010655.1	Ydr367wp
NP_010656.1	Ypr1p
NP_010657.1	Xrs2p
NP_010658.1	Ydr370cp
NP_010659.1	Sporulation-specific chitinase
NP_010660.1	Vps74p
NP_010661.1	N-myristoylated calcium-binding protein that may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily
NP_010662.1	Ydr374cp
NP_001032576.1	Ydr374w-ap
NP_010663.1	Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required for the incorporation of the Rip1p and Qcr10p subunits into the cytochrome bc(1) complex; member of the CDC48/PAS1/SEC18 ATPase family
NP_010664.1	Oxidoreductase of the mitochondrial inner membrane, involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability
NP_010665.1	Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
NP_010666.2	Lsm6p
NP_010667.1	Rga2p
NP_076888.1	hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
NP_010668.1	Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway
NP_010669.1	Yra1p
NP_219495.2	Ydr381c-ap
NP_010670.1	Rpp2bp
NP_010671.2	Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p- Nkp1p-Nkp2p-Ame1p-Mtw1p)
NP_010672.1	Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters
NP_010673.1	Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
NP_010674.1	Mus81p
NP_010675.1	Ydr387cp
NP_010676.1	Rvs167p
NP_010677.1	Sac7p
NP_010678.1	Uba2p
NP_010679.1	Ydr391cp
NP_010680.1	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters
NP_010681.1	She9p
NP_010682.1	Rpt3p
NP_010683.1	Sxm1p
NP_010685.1	Subunit of a heterodimeric NC2 transcription regulator complex with Bur6p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta
NP_010686.1	Utp5p
NP_010687.1	Hpt1p
NP_010688.2	Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways
NP_010690.1	N-formyltyrosine oxidase, sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s
NP_010691.1	Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure
NP_010692.1	Rpb7p
NP_010693.1	Mrp20p
NP_010694.1	Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element
NP_010695.1	Trs120p
NP_010696.1	Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway
NP_010697.1	Siz1p
NP_010698.1	Ste14p
NP_010699.1	ER localized derlin-like family member involved in ER stress and homeostasis; not involved in ERAD or substrate retrotranslocation; interacts with CDC48; contains four transmembrane domains and two SHP boxes
NP_010700.1	Rrp17p
NP_010702.1	Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)
NP_010703.1	Ydr415cp
NP_010704.1	Syf1p
NP_010706.1	Rpl12bp
NP_010707.1	Rad30p
NP_010708.1	Serine/threonine rich cell surface protein; osmosensor; involved in the regulation of cell wall beta-1,3 glucan synthesis, bud site selection and hyperosmotic response; overexpression confers resistance to Hansenula mrakii killer toxin HM-1
NP_010709.1	Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids
NP_010710.2	Sip1p
NP_010711.1	Cad1p
NP_010712.1	Dyn2p
NP_010713.1	Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; forms a complex with Snx4p and Atg20p
NP_010715.1	Rpn9p
NP_010716.1	Ydr428cp
NP_010717.1	Tif35p
NP_010718.1	Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology
NP_010720.1	RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm
NP_010722.1	Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Sp homolog
NP_010723.1	Ppm1p
NP_010724.1	Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance
NP_010725.1	Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P
NP_010726.1	Thi74p
NP_010727.1	Protein involved in rDNA silencing; positively charged coiled-coil protein with limited similarity to myosin
NP_010728.1	Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes, functions in gene silencing at telomeres, most likely by directly modulating chromatin structure and Sir protein localization
NP_010729.1	Apt2p
NP_010731.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation
NP_010732.1	Ydr444wp
NP_010734.1	Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure
NP_010735.1	Rps17bp
NP_010736.1	Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes
NP_010737.1	Utp6p
NP_010738.1	Rps18ap
NP_010739.1	Yhp1p
NP_010740.1	Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer
NP_010741.1	Tsa2p
NP_010742.1	Guk1p
NP_010744.1	Nhx1p
NP_010745.1	Tom1p
NP_010746.1	Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle
NP_010747.1	Pfa5p
NP_010748.1	Tfb3p
NP_010749.1	Mfa1p
NP_001032577.1	Ydr461c-ap
NP_010750.1	Mrpl28p
NP_010751.2	Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing
NP_010752.1	Spp41p
NP_010753.1	Rmt2p
NP_010754.1	Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant
NP_010756.1	Tlg1p
NP_010757.1	Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30
NP_010758.2	Ugo1p
NP_010759.1	Rpl27bp
NP_010760.1	Trs31p
NP_010761.1	Splicing factor, component of the U4/U6-U5 snRNP complex
NP_010763.2	Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence
NP_010764.1	Ydr476cp
NP_010765.1	Snf1p
NP_010766.1	Subunit of RNase MRP, which cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP
NP_010767.1	Pex29p
NP_010768.1	Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription
NP_010769.1	Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides
NP_010770.1	Cwc21p
NP_010771.1	Kre2p
NP_010772.1	Vps52p
NP_010773.2	Vps72p
NP_010774.2	Vps60p
NP_010775.1	Rib3p
NP_010776.1	Pac11p
NP_010777.1	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
NP_010778.1	Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p
NP_010780.1	Membrane protein involved in zinc metabolism, member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc
NP_010781.1	Protein of unknown function; non-tagged protein detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media
NP_010782.2	Rsm28p
NP_010783.1	Vps3p
NP_010784.1	Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences in the 3' UTR and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA
NP_010785.1	Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p
NP_010786.1	Sec20p
NP_010787.1	Lcd1p
NP_010788.1	Rpl37bp
NP_010789.1	Protein required for partitioning of the 2-micron plasmid
NP_010790.1	Sam2p
NP_010791.1	Lpp1p
NP_010792.1	Spg3p
NP_010793.1	Psp1p
NP_010794.1	Ydr506cp
NP_010795.1	Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p
NP_010796.1	High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
NP_010798.1	Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics
NP_010799.1	Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes
NP_010800.1	Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation
NP_010801.1	Grx2p
NP_010802.1	Ydr514cp
NP_010803.1	Slf1p
NP_010804.1	Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression is regulated by glucose-repression transcription factors Mig1/2p
NP_010805.1	Grh1p
NP_010806.1	Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER
NP_010807.1	Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking
NP_010808.1	Ydr520cp
NP_010810.1	Sps2p
NP_010811.1	Sps1p
NP_010812.1	Age1p
NP_878066.1	Ydr524w-cp
NP_878067.1	Ydr524c-bp
NP_010814.1	Sna2p
NP_010816.1	Rba50p
NP_010817.1	Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A
NP_010818.1	Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly
NP_010819.1	Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa1p
NP_010820.1	Ydr531wp
NP_010821.1	Ydr532cp
NP_010822.1	Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site
NP_010823.1	Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
NP_010825.1	Stl1p
NP_010827.1	Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives; homolog of E. coli UbiX
NP_010828.1	Ydr539wp
NP_010829.1	hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci
NP_010830.1	Ydr541cp
NP_010834.1	Yrf1-1p
NP_012092.1	Yil177cp
NP_012095.1	Vth1p
NP_012096.1	Yil172cp
NP_012097.1	Yil169cp
NP_012100.1	Yil166cp
NP_012101.1	Yil165cp
NP_012102.1	Nitrilase, member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene
NP_012104.1	Suc2p
NP_012105.1	Yil161wp
NP_012106.1	Pot1p
NP_012107.1	Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1
NP_012108.1	Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_012109.1	Mitochondrial inner membrane protein required for assembly of the cytochrome c oxidase complex (complex IV); interacts with complex IV assembly factor Shy1p during the early stages of assembly
NP_001027534.1	Yil156w-bp
NP_012110.1	Ubp7p
NP_012111.1	Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner
NP_012112.1	Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants, contains a C-terminal leucine-rich repeat
NP_012113.1	Rrd1p
NP_012114.1	Yil152wp
NP_012115.1	Yil151cp
NP_012116.1	Mcm10p
NP_012117.1	Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length
NP_012118.1	Rpl40ap
NP_012119.1	Sln1p
NP_012120.1	Non-essential protein of unknown function
NP_012121.2	Pantothenate synthase, also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC
NP_012122.1	Tid3p
NP_012123.1	Ssl2p
NP_012124.1	Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
NP_012126.1	Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate
NP_012127.1	Rev7p
NP_012128.1	Tpm2p
NP_012129.1	Tma108p
NP_012130.1	Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane
NP_012131.1	Vhs2p
NP_878096.1	Yil134c-ap
NP_012132.1	Protein required for transport of flavin adenine dinucleotide (FAD), a synthesis product of riboflavin, across the mitochondrial membrane
NP_012133.1	Rpl16ap
NP_012134.1	Protein required for accurate chromosome segregation during meiosis
NP_012135.1	Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching
NP_012136.1	Proposed transcriptional activator, member of the Gal4p family of zinc cluster proteins
NP_012137.1	Tao3p
NP_012138.1	Met18p
NP_012139.1	Yil127cp
NP_012140.1	Sth1p
NP_012141.1	Kgd1p
NP_012142.1	NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones
NP_012143.1	Sim1p
NP_012144.1	Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated
NP_012145.1	Qdr2p
NP_012146.1	Qdr1p
NP_012147.1	Rpi1p
NP_012148.1	Rho3p
NP_012149.1	Prm5p
NP_012150.1	Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
NP_012151.1	Nup159p
NP_012152.1	Putative mitochondrial porin (voltage-dependent anion channel), related to Por1p but not required for mitochondrial membrane permeability or mitochondrial osmotic stability
NP_012153.1	Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock
NP_012154.1	Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
NP_012155.1	Subunit Vb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during anaerobic growth while its isoform Va (Cox5Ap) is expressed during aerobic growth
NP_012156.1	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion mutant exhibits a weak vacuolar protein sorting defect, enhanced resistance to caspofungin, and is synthetically lethal with MEN mutants
NP_012157.1	Sec24p
NP_012158.1	Yil108wp
NP_012159.1	Pfk26p
NP_012160.2	Mob1p
NP_012161.1	Slm1p
NP_012162.1	Shq1p
NP_012163.1	Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p
NP_001032579.1	Yil102c-ap
NP_012164.1	Yil102cp
NP_012165.1	Xbp1p
NP_012167.1	Sga1p
NP_012168.1	Mitochondrial matrix protein, required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p
NP_012169.1	Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains CTLH domain
NP_012170.1	Yil096cp
NP_012171.1	Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex
NP_012172.1	Lys12p
NP_012173.1	Rsm25p
NP_012174.1	Yil092wp
NP_012175.1	Yil091cp
NP_012176.1	Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells
NP_012177.1	Yil089wp
NP_012178.1	Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
NP_012179.1	Putative protein of unknown function; protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_012181.1	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
NP_012182.1	Sds3p
NP_012183.1	Yil083cp
NP_012184.1	Yil082w-ap
NP_012186.1	RING finger protein that interacts with the arginine methyltransferase Hmt1p to regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air2p
NP_116578.1	Ths1p
NP_012188.1	Yil077cp
NP_012189.2	Sec28p
NP_012190.1	Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p
NP_012191.1	Ser33p
NP_012192.2	Spo22p
NP_012193.1	Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for homologous chromosome synapsis and chiasma formation
NP_085069.1	Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain
NP_012194.1	Mam33p
NP_012195.1	Rps24bp
NP_012196.1	Sec6p
NP_012197.1	Yil067cp
NP_012198.1	Rnr3p
NP_012199.1	Mitochondrial outer membrane protein involved in membrane fission, required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation
NP_012200.1	Yil064wp
NP_012201.1	Yrb2p
NP_012202.1	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
NP_012203.1	Snp1p
NP_012204.1	Yil060wp
NP_012207.1	Yil057cp
NP_012208.1	Vhr1p
NP_012209.1	Yil055cp
NP_012211.2	Rhr2p
NP_012212.1	Rpl34bp
NP_012213.1	Mmf1p
NP_012214.1	Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated
NP_012215.1	Protein of unknown function, involved in filamentous growth
NP_012216.1	Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus
NP_012217.1	Syg1p
NP_878097.1	Yil046w-ap
NP_012218.1	Met30p
NP_012219.1	Putative type-1 protein phosphatase targeting subunit that tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase
NP_012220.1	Age2p
NP_012221.2	Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia
NP_012222.1	Pkp1p
NP_012223.1	Gvp36p
NP_012224.1	Protein involved in nucleocytoplasmic transport of mRNA
NP_012225.1	Ted1p
NP_012226.1	Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation
NP_012227.1	Prm2p
NP_012228.1	Cst6p
NP_012229.1	Cka1p
NP_012230.1	Cap2p
NP_012231.1	Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation
NP_012233.1	Ulp2p
NP_012234.1	Ubiquitin-protein ligase of the ER/nuclear envelope, required for degradation of Alpha2p and other proteins containing a Deg1 degradation signal; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation
NP_012235.1	Yil029cp
NP_012237.1	Protein of unknown function; null mutant shows K1 killer toxin resistance
NP_012238.1	Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability
NP_012240.1	Yil024cp
NP_012241.1	Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family
NP_012242.1	Tim44p
NP_012243.1	Rpb3p
NP_012244.1	Phosphoribosyl-5-amino-1-phosphoribosyl-4- imidazolecarboxiamide isomerase, catalyzes the fourth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
NP_012245.1	Protein required for pre-rRNA processing and 40S ribosomal subunit assembly
NP_012246.1	Rpl2bp
NP_012247.1	Vid28p
NP_012248.1	Snl1p
NP_012249.1	Bar1p
NP_012250.1	Yil014c-ap
NP_012251.1	Mnt3p
NP_012252.1	Pdr11p
NP_012254.1	Tir3p
NP_012255.1	Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase during post-diauxic growth
NP_012256.1	Est3p
NP_012257.1	Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
NP_012258.1	Urm1p
NP_012259.1	Protein with similarity to the p27 subunit of mammalian proteasome modulator; not essential; interacts with Rpn4p
NP_012260.1	Yia6p
NP_012261.1	Eps1p
NP_012262.1	Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins
NP_012263.1	Highly conserved, iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol
NP_878098.1	Yil002w-ap
NP_012264.1	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth
NP_012266.1	Sgn1p
NP_012267.1	Mph1p
NP_012268.1	Protein of unknown function; may interact with ribosomes; GFP-fusion protein colocalizes with Sac1p to the actin cytoskeleton; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_012269.1	Djp1p
NP_012270.1	Ist3p
NP_012271.1	Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease
NP_012272.1	Yir007wp
NP_012273.1	Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair
NP_012274.1	U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro; does not contain the conserved C-terminal RNA binding domain found in other family members
NP_012275.1	Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation
NP_012276.1	Sts1p
NP_012277.1	Sqt1p
NP_012278.1	Protein containing GATA family zinc finger motifs
NP_012279.2	Yir014wp
NP_012280.1	Subunit of nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits
NP_012281.1	Yir016wp
NP_012282.1	Transcriptional activator in the Cbf1p-Met4p-Met28p complex, participates in the regulation of sulfur metabolism
NP_012283.1	Yap5p
NP_878099.1	Yir018c-ap
NP_012284.1	Muc1p
NP_012287.1	Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
NP_878100.1	Yir021w-ap
NP_012288.1	Sec11p
NP_012289.1	Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
NP_012290.1	Yir024cp
NP_012291.1	Subunit of the anaphase-promoting complex (APC); needed for meiotic nuclear division
NP_012292.1	Yvh1p
NP_012293.1	Dal1p
NP_012294.1	Dal4p
NP_012295.1	Dal2p
NP_012296.1	Protein of unknown function, expression is sensitive to nitrogen catabolite repression and regulated by Dal80p; contains transmembrane domain
NP_012297.1	Malate synthase, role in allantoin degradation unknown; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
NP_012298.1	Ureidoglycolate hydrolase, converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression sensitive to nitrogen catabolite repression
NP_012299.1	Mga2p
NP_012300.1	Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway
NP_012301.1	Yir035cp
NP_012302.1	Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52 foci
NP_012303.1	Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor
NP_012304.1	Gtt1p
NP_012305.1	Yps6p
NP_012308.1	Yir042cp
NP_009305.1	Subunit I of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits
NP_009306.1	Endonuclease I-SceIV, involved in intron mobility; encoded by a mobile group I intron within the mitochondrial COX1 gene
NP_009307.2	Endonuclease I-SceII, encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity
NP_009308.2	Endonuclease I-SceIII, encoded by a mobile group I intron within the mitochondrial COX1 gene
NP_009309.1	Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene
NP_009310.1	Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene
NP_009311.2	Protein of unknown function, encoded within an intron of the mitochondrial COX1 gene; translational initiation codon is predicted to be ATA rather than ATG
NP_009312.1	Subunit 8 of the F0 sector of mitochondrial inner membrane F1-F0 ATP synthase, encoded on the mitochondrial genome
NP_009313.1	Mitochondrially encoded subunit 6 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
NP_009315.1	Cytochrome b, mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p
NP_009316.1	Mitochondrial mRNA maturase, forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA
NP_009317.1	Mitochondrial mRNA maturase, forms a complex with Mrs1p to mediate splicing of the bI3 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA
NP_009318.1	Mitochondrial mRNA maturase with a role in splicing, encoded by both exon and intron sequences of partially processed COB mRNA
NP_009319.1	Oli1p
NP_009320.1	Var1p
NP_009324.1	Sceip
NP_009326.1	Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits
NP_009327.1	Q0255p
NP_009328.1	Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits
NP_010835.1	Yel077cp
NP_010836.1	Yel076c-ap
NP_010837.1	Yel076cp
NP_010839.1	Yel075cp
NP_010841.1	Yel073cp
NP_010842.1	Rmd6p
NP_010843.1	Dld3p
NP_010844.1	Dsf1p
NP_010845.1	Hxt13p
NP_010847.1	Yel067cp
NP_010848.1	Hpa3p
NP_010849.1	Sit1p
NP_010850.1	Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
NP_010851.1	Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance
NP_010852.2	Protein with a possible role in regulating expression of nitrogen permeases; transcription is induced in response to proline and urea; contains two PEST sequences; null mutant is resistant to cisplatin and doxorubicin
NP_010853.2	Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation
NP_010854.1	Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation
NP_058154.1	Subunit of the mitochondrial inner membrane peptidase, which is required for maturation of mitochondrial proteins of the intermembrane space; Som1p facilitates cleavage of a subset of substrates
NP_010856.1	Pcm1p
NP_010857.1	Yel057cp
NP_010858.1	Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
NP_010859.1	Pol5p
NP_010860.1	Rpl12ap
NP_010861.1	Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus; expression is glucose-repressible
NP_010862.1	Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain
NP_010863.1	Vma8p
NP_010864.1	Rml2p
NP_010865.1	Pau2p
NP_010866.1	Yel048cp
NP_010867.1	Yel047cp
NP_010868.1	Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis
NP_010870.1	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
NP_010871.1	Yel043wp
NP_010872.1	Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate
NP_010873.1	Yef1p
NP_010874.1	Utr2p
NP_010875.1	Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
NP_010876.2	Utr4p
NP_010877.1	Rad23p
NP_010878.1	Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol
NP_010879.1	Utr5p
NP_010880.1	Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification
NP_010882.1	Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
NP_010883.1	Spf1p
NP_010884.1	Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner; overexpression induces extensive mitochondrial DNA aggregations
NP_010885.1	Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection
NP_010887.1	Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis
NP_010888.1	Snu13p
NP_010889.1	Yel025cp
NP_010890.1	Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration
NP_010891.1	Yel023cp
NP_010892.1	Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p
NP_010893.1	Ura3p
NP_010894.1	Tim9p
NP_010895.1	hypothetical protein with low sequence identity to Pdc1p
NP_010896.1	SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination
NP_010897.1	Esa1p-associated factor, non-essential subunit of the NuA4 acetyltransferase complex
NP_010898.1	Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; nearly identical to PMP1
NP_010899.1	Protein of unknown function with a possible role in glutathione metabolism, as suggested by computational analysis of large-scale protein-protein interaction data; GFP-fusion protein localizes to the nuclear periphery
NP_010900.1	Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp1p and Pho5p; activity and expression enhanced during conditions of phosphate starvation
NP_010901.1	Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically affecting the function of the decapping enzyme Dcp1p; localizes to cytoplasmic mRNA processing bodies
NP_010903.1	Vac8p
NP_010904.2	Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro
NP_010905.1	Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
NP_010907.1	Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels
NP_010909.1	Yel007wp
NP_010910.1	Yea6p
NP_010911.1	Vab2p
NP_010912.1	Yea4p
NP_010913.2	Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
NP_010914.1	Wbp1p
NP_010915.1	Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52 foci
NP_010916.1	Mnn1p
NP_010917.1	Nop16p
NP_010918.1	Pmi40p
NP_010919.1	Protein of unknown function, localized to the mitochondrial outer membrane
NP_010920.1	Ynd1p
NP_010921.1	Nug1p
NP_010922.1	Pac2p
NP_010923.1	Tma20p
NP_010924.1	Sec3p
NP_010925.1	Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport
NP_010926.1	Yer010cp
NP_010927.1	Tir1p
NP_010928.1	Pre1p
NP_010929.1	Prp22p
NP_010930.1	Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX
NP_076437.1	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_010931.1	Long chain fatty acyl-CoA synthetase; accepts a wider range of acyl chain lengths than Faa1p, preferring C9:0-C13:0; involved in the activation of endogenous pools of fatty acids
NP_010932.1	Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally
NP_010933.1	Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes
NP_010934.1	Spc25p
NP_010935.1	Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance
NP_010936.1	Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p
NP_010937.1	Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
NP_010938.1	Rpn3p
NP_010939.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_010940.1	Pro3p
NP_010941.1	Yat2p
NP_010942.1	Gcd11p
NP_010943.1	Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline
NP_010944.1	One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain
NP_010945.1	Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes
NP_010946.1	Smb1p
NP_010947.2	Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif
NP_010948.1	Ypt31p
NP_010949.2	Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate
NP_010950.1	Zrg8p
NP_010951.1	Yer034wp
NP_010952.1	RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p
NP_010953.1	Arb1p
NP_010954.1	Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p
NP_010955.1	Kre29p
NP_010956.1	Protein of unknown function, has homology to Vrg4p
NP_010957.1	Yer039c-ap
NP_010958.1	Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source
NP_010959.1	Yen1p
NP_010960.1	Peptide methionine sulfoxide reductase, reverses the oxidation of methionine residues; involved in oxidative damage repair, providing resistance to oxidative stress and regulation of lifespan
NP_010961.1	Sah1p
NP_010962.1	Erg28p
NP_010963.1	Meiosis-specific protein involved in recombination; required for chromosome synapsis; required for production of viable spores
NP_010964.1	Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources
NP_010965.1	Spo73p
NP_010966.1	Sap1p
NP_010967.1	Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly
NP_010968.1	Protein required for mitochondrial iron-sulfur cluster biosynthesis
NP_010969.1	Tpa1p
NP_010970.2	Rsm18p
NP_010971.1	JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe
NP_010972.1	Hom3p
NP_010973.1	Pic2p
NP_061492.1	Yer053c-ap
NP_010974.1	Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p
NP_010975.1	His1p
NP_010976.1	Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation
NP_010977.2	Rpl34ap
NP_010978.1	Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro
NP_010979.1	Protein required for assembly of cytochrome c oxidase
NP_010980.1	Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding
NP_010981.1	Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function
NP_010982.1	Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function
NP_010983.1	Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration
NP_010984.1	One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition
NP_010985.1	Tho1p
NP_010986.1	Yer064cp
NP_010987.1	Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose
NP_010988.1	Yer066wp
NP_010990.1	Yer067wp
NP_010991.1	Mot2p
NP_010992.1	Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p
NP_010993.1	Rnr1p
NP_010994.1	Yer071cp
NP_010995.1	Vtc1p
NP_010996.1	Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed
NP_010997.1	Rps24ap
NP_219496.2	Yos1p
NP_010998.1	Ptp3p
NP_010999.1	Yer076cp
NP_011001.1	Yer078cp
NP_878068.1	Yer078w-ap
NP_011002.1	Yer079wp
NP_011003.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)
NP_011004.1	Ser3p
NP_011005.1	Utp7p
NP_011006.2	Subunit of the GET complex; required for meiotic nuclear division and for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; may be involved in cell wall function
NP_011008.1	Yer085cp
NP_011009.1	Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation
NP_011010.1	Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation), severe growth defect in minimal glycerol media
NP_011011.1	Sbh1p
NP_011012.1	Protein of unknown function, involved in telomeric gene silencing and filamentation
NP_011013.1	Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; role in DNA checkpoint inactivation
NP_011014.1	Trp2p
NP_011015.1	Met6p
NP_011017.1	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
NP_011018.1	Tsc11p
NP_011019.1	Putative protein of unknown function; YER093C-A contains an intron; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_011020.1	Pup3p
NP_011021.1	Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein
NP_011022.1	Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH
NP_011024.1	Ubp9p
NP_011025.1	Prs2p
NP_011026.1	Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway
NP_011027.1	Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions
NP_011028.1	Rps8bp
NP_011029.1	Ssa4p
NP_011030.1	Rtt105p
NP_011031.1	Nup157p
NP_011032.1	Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle
NP_011033.1	Gle2p
NP_011034.1	Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene
NP_011035.1	Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1
NP_011036.1	Swi4p
NP_011037.1	Lsm4p
NP_011038.1	Tmn3p
NP_011039.1	Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
NP_011040.1	Spr6p
NP_011041.1	Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate
NP_011042.1	Rpl23bp
NP_011043.1	Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway
NP_011044.1	Vacuolar amino acid transporter, exports aspartate and glutamate from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
NP_011046.1	Scs2p
NP_011047.1	Yer121wp
NP_011048.1	Glo3p
NP_011049.2	Yck3p
NP_011050.1	Dse1p
NP_011051.1	Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; functions in multivesicular body sorting, heat shock response and ubiquitylation of arrested RNAPII; contains a hect (homologous to E6-AP carboxyl terminus) domain
NP_011052.1	Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA
NP_011053.1	Lcp5p
NP_011054.1	Yer128wp
NP_011055.1	Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
NP_011057.1	Rps26bp
NP_011058.1	Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions
NP_011059.1	Glc7p
NP_011060.1	Yer134cp
NP_011062.1	Gdi1p
NP_011063.1	Yer137cp
NP_011064.1	Yer138cp
NP_058155.1	Yer137c-ap
NP_011065.1	Yer138w-ap
NP_011066.1	Rtr1p
NP_011067.1	Yer140wp
NP_011068.1	Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase
NP_011069.1	Mag1p
NP_011070.1	Ddi1p
NP_011071.1	Ubp5p
NP_011072.1	High affinity iron permease involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron
NP_011073.1	Lsm5p
NP_011074.1	Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX
NP_011075.1	TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability
NP_011076.1	Pea2p
NP_011077.1	Spi1p
NP_011078.1	Ubp3p
NP_011079.1	Yer152cp
NP_011080.1	Pet122p
NP_011081.1	Oxa1p
NP_011082.1	Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence
NP_011083.1	Yer156cp
NP_011084.1	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_011085.1	Yer158cp
NP_011086.1	Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha
NP_011087.1	Yer160cp
NP_058156.1	Yer159c-ap
NP_011088.1	Spt2p
NP_011089.1	Rad4p
NP_011090.1	Yer163cp
NP_011091.1	Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SILK complexes
NP_011092.1	Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G
NP_011093.1	Dnf1p
NP_011094.1	Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations
NP_011095.1	Cca1p
NP_011096.1	Rph1p
NP_011097.1	Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background
NP_011098.1	Rad3p
NP_011099.1	RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD
NP_011100.1	Rad24p
NP_011101.1	Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage
NP_011102.1	Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle
NP_878069.1	Yer175w-ap
NP_011103.1	Ecm32p
NP_011104.1	Bmh1p
NP_011105.2	Pda1p
NP_011106.1	Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein
NP_011107.1	Protein required for sporulation, transcript is induced 7.5 hours after induction of meiosis, expected to play significant role in the formation of reproductive cells
NP_796378.1	Slo1p
NP_011109.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_011110.1	Fau1p
NP_011111.1	Yer184cp
NP_011112.1	Pug1p
NP_011113.1	Yer186cp
NP_011114.1	Yer187wp
NP_878070.1	Yer188c-ap
NP_011116.1	Yer189wp
NP_011117.1	Yrf1-2p
NP_001073292.1	Yer190c-bp
NP_116587.1	Yfl068wp
NP_116588.1	Yfl067wp
NP_116589.1	Yfl066cp
NP_116590.1	Yfl065cp
NP_116591.1	Yfl064cp
NP_116593.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_116594.1	Protein whose expression is induced by DNA damage
NP_116595.1	Sno3p
NP_116596.1	Snz3p
NP_116597.1	Thi5p
NP_116598.1	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
NP_116599.1	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response
NP_116600.1	Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation
NP_116601.1	Yfl054cp
NP_116602.1	Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation
NP_116603.1	Yfl052wp
NP_116576.1	Yfl051cp
NP_116604.1	Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions
NP_116605.1	Swp82p
NP_116606.1	Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport
NP_428268.1	Rgd2p
NP_116608.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_116609.1	Sec53p
NP_116610.1	Otu1p
NP_116611.1	Yfl042cp
NP_878071.1	Yfl041w-ap
NP_116612.1	Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport
NP_116613.1	Yfl040wp
NP_116614.1	Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions
NP_116615.1	Ypt1p
NP_116616.1	Tub2p
NP_116617.1	Rpo41p
NP_116618.1	Mob2p
NP_116619.1	Rpl22bp
NP_116583.1	Yfl034wp
NP_116620.1	Rim15p
NP_116622.1	bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway utilizing Ire1p, Trl1p and Ada5p facilitates efficient Hac1p synthesis
NP_116623.1	Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases
NP_116624.1	Cyclin-dependent kinase-activating kinase required for passage through the cell cycle, phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases
NP_116625.1	Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; putative ABC ATPase; interacts with Ssn2p, Ssn3p, and Ssn8p
NP_444296.1	Gyp8p
NP_116627.1	Ste2p
NP_116628.1	GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules
NP_116629.1	Epl1p
NP_683715.1	Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by the TOR kinase; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_116631.1	Frs2p
NP_116632.1	Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p
NP_116633.1	Pau5p
NP_116635.1	Lpd1p
NP_116636.1	Smx2p
NP_116637.1	Gna1p
NP_116638.1	Protein involved in folding of mitochondrially synthesized proteins in the mitochondrial matrix; localizes to the mitochondrial inner membrane; member of the DnaJ family of molecular chaperones
NP_116640.1	Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways
NP_116641.1	Subunit of the INO80 chromatin remodeling complex
NP_116643.1	Yfl012wp
NP_116644.1	Putative hexose transporter, expressed at low levels and expression is repressed by glucose
NP_116645.1	Protein required for the negative regulation by ammonia of Gap1p, which is a general amino acid permease
NP_570898.1	Wwm1p
NP_116585.1	F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p
NP_116647.1	Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure
NP_116648.2	Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200
NP_116650.1	Secretory vesicle-associated Rab GTPase essential for exocytosis; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane
NP_116651.1	Vtc2p
NP_116652.1	Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein
NP_116653.1	Yfl002w-ap
NP_058157.1	Yfl002w-bp
NP_116654.1	Spb4p
NP_116655.1	Non-essential tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm
NP_116656.1	Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles
NP_116657.1	Nic96p
NP_116658.1	Ypi1p
NP_116659.1	Rpn11p
NP_116660.1	Sad1p
NP_116661.1	Yfr006wp
NP_116662.1	Yfh7p
NP_116663.1	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p
NP_116664.1	Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA
NP_116665.1	Ubp6p
NP_116666.1	Putative protein of unknown function; non-tagged protein is detected in highly purified mitochondria; null mutant displays increased frequency of mitochondrial genome loss (petite formation) and reduced growth rate in minimal glycerol media
NP_116667.1	Yfr012wp
NP_076889.1	Yfr012w-ap
NP_116668.1	Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; has homology to Esc8p, which is involved in silencing
NP_116669.1	Cmk1p
NP_116670.1	Gsy1p
NP_116671.1	Yfr016cp
NP_116672.1	Yfr017cp
NP_116673.1	Yfr018cp
NP_116674.1	Fab1p
NP_444297.1	Phosphoinositide binding protein required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein
NP_116677.1	Rog3p
NP_116678.1	Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p
NP_219497.1	Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
NP_116681.1	Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
NP_116682.1	Yfr026cp
NP_116683.1	Eco1p
NP_116684.1	Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit
NP_116685.1	Ptr3p
NP_116686.1	Subunit alpha of assimilatory sulfite reductase, which is responsible for the conversion of sulfite into sulfide
NP_116687.1	Smc2p
NP_116688.1	Rpl2ap
NP_116689.1	Yfr032cp
NP_116690.1	Rpl29p
NP_878072.1	Yfr032c-bp
NP_116691.1	Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1
NP_116692.1	Pho4p
NP_116693.1	Yfr035cp
NP_116694.1	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_116695.1	Rsc8p
NP_116696.2	Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52 foci
NP_116697.1	Yfr039cp
NP_116698.2	Sap155p
NP_116699.1	Type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response
NP_116700.1	Protein of unknown function required for cell viability; localizes to the endoplasmic reticulum membrane
NP_116701.1	hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci
NP_116702.1	Probable di- and tri-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)
NP_116703.3	Yfr045wp
NP_116704.1	Kinetochore protein of unknown function; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1.
NP_602317.1	Quinolinate phosphoribosyl transferase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
NP_683716.1	Rmd8p
NP_116707.1	Ymr31p
NP_116708.1	Pre4p
NP_116709.1	Ret2p
NP_116710.1	Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p
NP_116711.1	Hxk1p
NP_116714.1	Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52 foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
NP_116715.1	Yfr057wp
NP_011251.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_011252.1	Ygl262wp
NP_011253.1	Putative protein of unknown function; mRNA expression appears to be regulated by SUT1 and UPC2
NP_011254.1	Ygl260wp
NP_011255.1	Yps5p
NP_076890.1	Ygl258w-ap
NP_011256.1	Vel1p
NP_011257.1	Mnt2p
NP_011258.1	Alcohol dehydrogenase isoenzyme type IV, dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency
NP_011259.1	Zrt1p
NP_011260.1	Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers
NP_011261.1	Hxk2p
NP_011262.1	Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p
NP_011263.2	Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity
NP_011264.2	Rmr1p
NP_011265.1	Zip2p
NP_011266.1	Pde1p
NP_011267.1	Essential nuclear envelope integral membrane protein required for nuclear transport; depletion alters nucleoporin distribution and nuclear envelope morphology, suggesting a role in the spatial organization of nuclear pores
NP_011268.1	Rai1p
NP_011269.2	Gus1p
NP_011270.1	Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance
NP_011271.1	tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala
NP_011272.1	Ygl242cp
NP_011273.1	Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear
NP_011274.2	Processivity factor required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis
NP_011276.1	Nuclear envelope protein that mediates the nuclear export of importin alpha (Srp1p), homolog of metazoan CAS protein, required for accurate chromosome segregation
NP_011277.1	Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding
NP_011278.2	Mto1p
NP_011279.1	Ygl235wp
NP_011280.1	Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities
NP_011281.1	Sec15p
NP_011282.1	Tan1p
NP_011283.1	Ygl231cp
NP_011284.1	Ygl230cp
NP_011285.1	Sap4p
NP_011286.1	She10p
NP_011287.1	Vid30p
NP_011288.1	Zeta subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins
NP_011289.1	Ygl226wp
NP_011290.1	Vrg4p
NP_011291.1	Sdt1p
NP_011292.1	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_011293.1	RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p
NP_011294.1	Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_011295.1	Putative protein of unknown function; (GFP)-fusion protein localizes to the cytoplasm and the nucleus; null mutant displays decreased mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_011296.1	Mitochondrial outer membrane protein, required for normal mitochondrial morphology and inheritance; localizes to dots on the mitochondrial surface near mtDNA nucleoids; interacts genetically with MDM31 and MDM32
NP_011299.1	Kip3p
NP_011300.1	Cyclin-like protein that interacts with Pho85p; has sequence similarity to G1 cyclins PCL1 and PCL2
NP_011302.1	Ski8p
NP_011303.1	Vam7p
NP_011304.2	Protein required for thiolation of the uridine at the wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae
NP_011305.1	Ypt32p
NP_011306.1	Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
NP_011307.1	Sip2p
NP_011308.1	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure
NP_011309.1	Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; two heavy chains form the clathrin triskelion structural component; the light chain (CLC1) is thought to regulate function
NP_011310.1	Pox1p
NP_011312.1	Protease involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins
NP_011313.1	Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis
NP_011314.2	Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
NP_011315.1	Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport
NP_011317.2	Yip4p
NP_011318.1	Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions
NP_011319.2	Dsd1p
NP_011320.1	Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA
NP_001032578.1	Ygl194c-ap
NP_011321.1	Hos2p
NP_011322.1	Ygl193cp
NP_011323.1	Probable mRNA N6-adenosine methyltransferase that is required for IME1 transcript accumulation and for sporulation; expression is induced in starved MATa/MAT alpha diploid cells
NP_011324.1	Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP
NP_011325.1	Non-essential regulatory subunit B of protein phosphatase 2A, which has multiple roles in mitosis and protein biosynthesis; involved in regulation of mitotic exit; found in the nucleus of most cells, also at the bud neck and at the bud tip
NP_011326.1	Rps26ap
NP_878073.1	Ygl188c-ap
NP_011328.1	Subunit IV of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; N-terminal 25 residues of precursor are cleaved during mitochondrial import; phosphorylated
NP_011329.1	Tpn1p
NP_011330.1	Ygl185cp
NP_011331.1	Str3p
NP_011332.2	Protein required for recombination and meiotic nuclear division; forms a complex with Hop2p, which is involved in chromosome pairing and repair of meiotic double-strand breaks
NP_011334.1	Protein containing a zinc-finger in the N-terminus and a long Gln-rich region in the C-terminus; regulates ultradian rhythm, cell size, cell cycle, lifespan, sporulation, heat tolerance, and multidrug transport
NP_011335.1	Protein serine/threonine kinase, required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for pre-autophagosome formation; forms a complex with Atg13p and Atg17p
NP_011336.1	Tos3p
NP_011337.1	Mpt5p
NP_011339.1	Ygl176cp
NP_011340.1	Sae2p
NP_011341.1	Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern
NP_011342.1	Kem1p
NP_011343.1	Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for nuclear export of ribosomes
NP_011344.1	Rok1p
NP_011345.1	Spo74p
NP_011346.1	Sua5p
NP_011347.1	Protein required for hydroxyurea resistance; has possible roles in DNA replication and maintenance of proper telomere length
NP_011348.1	Pmr1p
NP_011349.1	Cup2p
NP_011351.1	Yrb30p
NP_011352.1	Rad54p
NP_011353.1	Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression
NP_011354.1	Yip5p
NP_011355.1	Putative protein of unknown function; similar to iron/copper reductases (FRE1-8), possibly involved in iron homeostasis; may interact with ribosomes, null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_011356.1	Ygl159wp
NP_011357.1	Rck1p
NP_011358.1	Ygl157wp
NP_011359.1	Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway
NP_011360.1	Cdc43p
NP_011361.1	Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine
NP_011362.1	Pex14p
NP_011364.1	Nut1p
NP_011365.1	Ino80p
NP_011367.1	Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids
NP_011368.1	Rpl9ap
NP_011369.1	Ygl146cp
NP_116577.1	Tip20p
NP_011371.1	Rog1p
NP_011372.1	Mrf1p
NP_011373.1	Integral membrane protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the GPI core structure; human PIG-Bp is a functional homolog
NP_011374.1	Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability
NP_011375.1	Ygl140cp
NP_011376.1	Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER
NP_011377.1	Ygl138cp
NP_011378.1	Sec27p
NP_011379.1	Mrm2p
NP_011380.1	Rpl1bp
NP_011381.1	Pho85p cyclin; recruits, activates, and targets Pho85p cyclin-dependent protein kinase to its substrate
NP_011382.1	Itc1p
NP_011384.1	Snt2p
NP_011385.1	Ceg1p
NP_011386.1	Rsm23p
NP_011387.2	Cwc23p
NP_011388.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits
NP_011389.1	Scs3p
NP_011390.2	Met13p
NP_011391.1	Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate
NP_011392.1	Rps2p
NP_011393.1	Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; has nuclear localization signal sequence that binds to Kap104p; required for poly(A) tail length control and nuclear mRNA export
NP_011394.1	Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Grp1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p
NP_011395.1	RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome
NP_011396.1	Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis
NP_011398.1	Ygl117wp
NP_011399.1	Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate
NP_011400.1	Snf4p
NP_011401.1	Ygl114wp
NP_011402.1	Sld3p
NP_011403.1	Taf6p
NP_011404.1	Nsa1p
NP_011405.1	Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination
NP_011407.1	Ygl108cp
NP_011408.1	Rmd9p
NP_011409.1	Mlc1p
NP_011410.1	Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids
NP_011411.1	Vps73p
NP_011412.1	Rpl28p
NP_011414.1	Ygl101wp
NP_011415.1	Seh1p
NP_011416.1	Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm
NP_011417.1	Use1p
NP_011418.1	Srm1p
NP_011419.1	Tos8p
NP_011420.1	Vps45p
NP_011421.1	Pan2p
NP_011422.1	Spc105p
NP_011423.1	Nup145p
NP_011424.1	Nbp35p
NP_011425.1	Lif1p
NP_011426.1	Mf(alpha)2p
NP_011428.1	Protein involved in error-free postreplication DNA repair; forms a heteromeric complex with Ubc13p that has a ubiquitin-conjugating activity; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p
NP_011429.1	Mad1p
NP_011430.1	Ygl085wp
NP_011431.1	Plasma membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases
NP_011432.1	Scy1p
NP_011433.1	Ygl082wp
NP_011434.1	Ygl081wp
NP_011435.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_011436.1	Ygl079wp
NP_011437.1	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
NP_011438.1	Hnm1p
NP_011439.1	Rpl7ap
NP_011440.1	Mps2p
NP_011442.1	Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated
NP_011444.1	Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability
NP_011445.1	Rpb9p
NP_011447.1	Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7/L12 ribosomal protein; required for normal respiratory growth
NP_011448.1	Npy1p
NP_011449.1	Sgf73p
NP_011450.1	Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol
NP_011451.1	Mrh4p
NP_011452.1	Pus2p
NP_011453.1	Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis
NP_011454.1	Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis
NP_011455.1	Ybp2p
NP_011456.2	Ygl059wp
NP_011457.1	Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)
NP_011458.1	Ygl057cp
NP_011459.1	Sds23p
NP_011460.1	Ole1p
NP_011461.1	Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon
NP_011462.1	Prm8p
NP_011464.1	Putative integral membrane protein, involved in vesicle formation; forms complex with Mst28p; member of DUP240 gene family; binds COPI and COPII vesicles
NP_011465.1	Tyw3p
NP_011466.1	Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4631p
NP_011467.1	Rpt6p
NP_011468.1	Catalytic component of UDP-GlcNAc transferase, required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases
NP_011470.2	Rim8p
NP_011471.1	Rna15p
NP_011472.1	General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites
NP_878074.1	Ygl041c-bp
NP_001106172.1	Ygl041w-ap
NP_011475.1	Hem2p
NP_011476.1	Ygl039wp
NP_011477.1	Och1p
NP_011478.1	Pnc1p
NP_011479.1	Ygl036wp
NP_011480.1	Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
NP_011482.2	Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair
NP_011483.1	Aga2p
NP_011484.1	Rpl24ap
NP_011485.1	Rpl30p
NP_011486.1	Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress
NP_011487.1	Scw11p
NP_011488.1	Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress
NP_011489.1	Tryptophan synthase involved in tryptophan biosynthesis, regulated by the general control system of amino acid biosynthesis
NP_011490.2	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor
NP_011492.1	Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27
NP_011493.1	Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis
NP_011494.1	Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins
NP_011495.1	Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance
NP_011496.1	Ckb1p
NP_011497.1	Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix
NP_011498.1	Ate1p
NP_011499.1	Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance
NP_011501.1	Puf4p
NP_011502.1	Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes
NP_011503.1	Erg4p
NP_011504.1	Scl1p
NP_011505.1	Ygl010wp
NP_011506.1	Leu1p
NP_011507.1	Pma1p
NP_878075.1	Ygl007c-ap
NP_878076.1	Ygl006w-ap
NP_011509.1	Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a
NP_011510.1	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_011511.1	Rpn14p
NP_011512.1	Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including CDC20, ASE1, CIN8 and FIN1
NP_011513.1	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_011514.1	Erg26p
NP_011515.2	Putative protein of unknown function with similarity to methyltransferase family members; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in S. cerevisiae
NP_011516.1	Swc4p
NP_011517.1	Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21
NP_011518.1	Pex31p
NP_011519.1	Tfg2p
NP_011520.2	Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, part of snRNP U5, interacts with Slu7p
NP_011521.1	Muq1p
NP_011522.1	Stf2p
NP_011523.1	t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but not functionally redundant with Spo20p; SNAP-25 homolog
NP_011524.1	Nma2p
NP_011526.1	Ygr012wp
NP_011527.1	Snu71p
NP_011528.1	Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate
NP_011529.1	Ygr015cp
NP_011530.1	Ygr016wp
NP_011531.1	Ygr017wp
NP_011533.1	Uga1p
NP_011534.1	Vma7p
NP_011535.1	Ygr021wp
NP_011537.1	Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations
NP_011538.1	tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes
NP_011540.1	Ygr026wp
NP_011541.1	Rps25ap
NP_058158.1	Ygr027w-bp
NP_058159.1	Ygr027w-ap
NP_011542.1	Msp1p
NP_011543.2	Flavin-linked sulfhydryl oxidase of the mitochondrial intermembrane space (IMS), oxidizes Mia40p as part of a disulfide relay system that promotes IMS retention of imported proteins; ortholog of human hepatopoietin (ALR)
NP_011544.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
NP_011545.1	Ygr031wp
NP_011546.1	Gsc2p
NP_011547.1	Tim21p
NP_011548.2	Rpl26bp
NP_011549.1	Ygr035cp
NP_878077.1	Ygr035w-ap
NP_011550.1	Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER, cleaves the anhydride linkage in Dol-P-P, required for Dol-P-P-linked oligosaccharide intermediate synthesis and protein N-glycosylation
NP_011551.1	Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes
NP_011552.1	Orm1p
NP_058160.1	Ygr038c-bp
NP_058161.1	Ygr038c-ap
NP_011554.1	Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
NP_011555.1	Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole
NP_011556.1	Ygr042wp
NP_011557.1	Protein of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift; null mutant non-quiescent cells exhibit reduced reproductive capacity
NP_011558.1	Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-a2 regulator; mediates cell type control of sporulation
NP_011560.1	Tam41p
NP_011561.1	Tfc4p
NP_011562.1	Ufd1p
NP_011563.1	Scm4p
NP_011566.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_011567.1	Ygr053cp
NP_011568.1	Ygr054wp
NP_011569.1	Mup1p
NP_011570.1	Rsc1p
NP_011571.2	Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
NP_011572.1	Penta-EF-hand protein required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2
NP_011573.1	Spr3p
NP_011574.1	Erg25p
NP_011575.1	Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway
NP_011576.1	Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC
NP_011577.1	Spt4p
NP_011579.1	Vht1p
NP_011580.1	Ygr066cp
NP_011581.1	Ygr067cp
NP_011582.1	Ygr068cp
NP_011584.1	Rom1p
NP_011585.1	Ygr071cp
NP_011586.1	Upf3p
NP_011588.1	Smd1p
NP_011589.1	Unique component of the U4/U6.U5 tri-snRNP particle, required for conformational changes which result in the catalytic activation of the spliceosome; dispensible for spliceosome assembly
NP_011590.1	Mrpl25p
NP_011591.1	Pex8p
NP_011592.1	Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding
NP_011593.1	Ygr079wp
NP_011594.1	Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly
NP_011595.1	Slx9p
NP_011596.1	Tom20p
NP_011597.1	Gcd2p
NP_011598.1	Mrp13p
NP_011599.1	Rpl11bp
NP_011600.1	Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria
NP_011601.1	Pdc6p
NP_011602.2	Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide
NP_011603.1	Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation
NP_011604.1	Utp22p
NP_011605.1	Splicing factor, component of the U4/U6-U5 snRNP complex
NP_011606.1	Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis
NP_011607.1	Putative debranching enzyme associated ribonuclease; green fluorescent protein (GFP)-fusion protein localizes to the nucleus
NP_011608.1	Vas1p
NP_011609.2	Rrp46p
NP_011610.1	Tpc1p
NP_011611.1	Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes
NP_011612.1	Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p
NP_011613.1	Tel2p
NP_011614.1	Mdr1p
NP_011615.1	Pcp1p
NP_011616.1	Ygr102cp
NP_011617.1	Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis; constituent of several different pre-ribosomal particles; required for exit from G0 and the initiation of cell proliferation
NP_011618.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance
NP_011619.1	Vma21p
NP_011620.1	Ygr106cp
NP_011622.1	Clb1p
NP_011623.1	Clb6p
NP_011624.1	Ygr109w-bp
NP_058162.1	Ygr109w-ap
NP_011625.1	Ygr110wp
NP_011626.1	Ygr111wp
NP_011627.1	Shy1p
NP_011628.2	Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; Ipl1p target for regulating kinetochore-MT attachments
NP_011631.1	Spt6p
NP_011632.1	Ygr117cp
NP_011633.1	Rps23ap
NP_011634.1	Nup57p
NP_011635.2	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_011636.1	Mep1p
NP_878078.1	Ygr121w-ap
NP_011637.1	Ygr122wp
NP_011639.1	Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; computational analyses suggest roles in phosphate metabolism and rRNA processing
NP_011640.1	Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
NP_011641.1	Ygr125wp
NP_011642.1	Ygr126wp
NP_011643.1	Ygr127wp
NP_011644.1	Utp8p
NP_011645.1	Syf2p
NP_011646.1	Ygr130cp
NP_011647.1	Ygr131wp
NP_011648.1	Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation
NP_011649.1	Pex4p
NP_011650.1	Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation
NP_011651.1	Pre9p
NP_011652.1	Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
NP_011654.1	Tpo2p
NP_011656.1	Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
NP_011657.1	Vps62p
NP_011658.1	v-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi; modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase
NP_011659.1	Skn1p
NP_011660.1	Thiazole synthase, catalyzes formation of the thiazole moiety of thiamin pyrophosphate; required for thiamine biosynthesis and for mitochondrial genome stability
NP_011661.1	Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p
NP_011662.1	Ygr146cp
NP_878079.1	Ygr146c-ap
NP_011663.1	Nat2p
NP_011664.1	Rpl24bp
NP_011665.1	Ygr149wp
NP_011666.1	Protein of unknown function, contains PPR motifs; mutant has growth defects on both non-fermentable carbon sources and rich medium; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_011668.1	Rsr1p
NP_011669.1	Ygr153wp
NP_011670.1	Omega-class glutathione transferase; induced under oxidative stress; putative peroxisomal localization
NP_011671.1	Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis
NP_011672.1	Pti1p
NP_011673.1	Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis
NP_011674.1	Mtr3p
NP_011675.1	Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
NP_011677.1	Rts3p
NP_001018033.1	Ygr161w-cp
NP_058163.1	Ygr161w-bp
NP_058164.1	Ygr161w-ap
NP_058165.1	Ygr161c-dp
NP_058166.1	Ygr161c-cp
NP_011678.1	Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p
NP_011679.1	Gtr2p
NP_011681.1	Mrps35p
NP_011682.1	Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP (transport protein particle) complex, which is involved in the late steps of endoplasmic reticulum to Golgi transport
NP_011683.1	Clc1p
NP_011684.1	Ygr168cp
NP_011685.1	Pus6p
NP_878080.1	Ygr169c-ap
NP_011686.1	Psd2p
NP_011687.1	Msm1p
NP_011688.1	Yip1p
NP_011689.1	Rbg2p
NP_011690.1	Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp3p and function is partially redundant with that of Cbp3p
NP_878081.1	Ygr174w-ap
NP_011691.1	Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine
NP_011693.1	Atf2p
NP_011694.1	Protein interacting with poly(A)-binding protein Pab1p; likely involved in controlling the extent of mRNA polyadenylation; forms a complex with Mkt1p that may regulate HO translation; interacts with Lsm12p in a copurification assay
NP_011695.1	Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly
NP_011696.1	Rnr4p
NP_011697.1	Tim13p
NP_011699.1	Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex
NP_011700.1	Ubr1p
NP_011701.1	Tys1p
NP_011702.1	Tfg1p
NP_011703.1	Protein of unknown function with similarity to human HMG1 and HMG2; localizes to the cytoplasm
NP_011704.1	Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p
NP_011705.1	Crh1p
NP_011707.1	Hip1p
NP_011708.1	Tdh3p
NP_011709.1	Pdx1p
NP_011710.1	Xylulokinase, converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains
NP_011711.1	Ski6p
NP_011712.1	Protein of unknown function, required for survival upon exposure to K1 killer toxin
NP_011713.1	Sng1p
NP_011714.1	Ypp1p
NP_011715.1	Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases
NP_011716.1	Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
NP_011717.2	Ygr201cp
NP_011718.1	Pct1p
NP_011719.1	Ygr203wp
NP_011720.1	Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine
NP_878082.1	Ygr204c-ap
NP_011721.1	Ygr205wp
NP_011722.1	Mvb12p
NP_011723.1	Ygr207cp
NP_011724.1	Ser2p
NP_011725.1	Trx2p
NP_011726.1	Ygr210cp
NP_011727.1	Zpr1p
NP_011728.1	Sli1p
NP_011729.1	Rta1p
NP_011730.1	Rps0ap
NP_011731.1	Rsm27p
NP_011732.1	Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs
NP_011733.1	Voltage-gated high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and co-localizes with Mid1p, suggesting Cch1p and Mid1p function together
NP_011734.1	Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus
NP_011736.1	Mrpl9p
NP_011737.1	Tos2p
NP_011738.1	Pet54p
NP_011739.1	Phosphatidylinositol 3,5-bisphosphate-binding protein, predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization
NP_011740.1	Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole
NP_011741.3	Ama1p
NP_011743.1	Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1
NP_011745.1	Smi1p
NP_011746.1	Protein with some similarity to Spo12p; overexpression bypasses need for Spo12p, but not required for meiosis
NP_011747.2	Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation
NP_011748.1	Regulatory, non-ATPase subunit of the 26S proteasome; homolog of the human oncoprotein gankyrin, which interacts with the retinoblastoma tumor suppressor (Rb) and cyclin-dependent kinase 4/6
NP_011749.1	Pho81p
NP_011750.1	Yhb1p
NP_011751.1	Ygr235cp
NP_011752.2	Spg1p
NP_011753.1	Ygr237cp
NP_011754.1	Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
NP_011755.1	Pex21p
NP_011756.1	Pfk1p
NP_878083.1	Ygr240c-ap
NP_011757.1	Yap1802p
NP_011759.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_011760.1	Lsc2p
NP_011761.1	Sda1p
NP_011762.1	TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB
NP_011763.1	Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression
NP_011764.1	Sol4p
NP_011765.1	Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
NP_011766.1	Ygr250cp
NP_011767.1	Ygr251wp
NP_011768.1	Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily
NP_011769.1	Pup2p
NP_011770.1	Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose
NP_011771.1	Putative flavin-dependent monooxygenase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes
NP_011772.1	Gnd2p
NP_011773.1	Mtm1p
NP_011774.1	Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein
NP_011776.1	Tna1p
NP_011777.1	Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools
NP_011778.1	Protein kinase proposed to be involved in bud-site selection, telomere uncapping and elongation, and transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Gon7p
NP_011779.1	Sterol deacetylase; component of the sterol acetylation/deacetylation cycle along with Atf2p; integral membrane protein with active site in the ER lumen; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum
NP_011780.1	Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
NP_011782.1	Ygr266wp
NP_011783.1	GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pathway
NP_011784.1	Hua1p
NP_011786.1	Yta7p
NP_011787.1	Slh1p
NP_076891.2	Protein of unknown function; null mutant is sensitive to hydroxyurea and is delayed in recovering from alpha-factor arrest; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus
NP_011789.1	Ygr273cp
NP_011790.1	Taf1p
NP_011791.2	Rtt102p
NP_011792.1	Rnh70p
NP_011793.1	Ygr277cp
NP_011794.1	Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putative spliceosomal component, based on computational analysis of large-scale protein-protein interaction data
NP_011795.1	Scw4p
NP_011796.1	Pxr1p
NP_011797.1	Yor1p
NP_011798.1	Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
NP_011799.1	Ygr283cp
NP_011800.1	Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo
NP_011801.1	Zuo1p
NP_011802.1	Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant
NP_011803.1	Ygr287cp
NP_011804.1	Mal13p
NP_011805.1	Maltose permease, inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters
NP_011808.1	Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus
NP_011811.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_011812.1	Yrf1-3p
NP_011813.1	Yhl050cp
NP_011814.1	Yhl049cp
NP_878084.1	Yhl048c-ap
NP_011815.1	Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response
NP_011816.1	Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to the siderophore triacetylfusarinine C
NP_011817.1	Putative protein of unknown function; not an essential gene
NP_011819.1	Yhl044wp
NP_011820.1	Putative protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_011821.1	Yhl042wp
NP_011823.1	Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores
NP_011824.1	Yhl039wp
NP_011825.1	Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene
NP_011827.1	Mup3p
NP_011828.1	Vmr1p
NP_011829.1	Sbp1p
NP_011830.1	Rpl8ap
NP_011831.1	Gut1p
NP_011832.1	v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28
NP_011833.1	Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome
NP_011834.1	Oca5p
NP_011835.1	Wsc4p
NP_011836.1	Transcriptional repressor involved in response to pH and in cell wall construction; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by proteolytic processing; similar to A. nidulans PacC
NP_011837.2	Yhl026cp
NP_011838.1	Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p
NP_011839.1	Rim4p
NP_011840.1	Rmd11p
NP_011841.1	Spo11p
NP_011842.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)
NP_011843.1	Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance
NP_011844.1	Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport
NP_011845.1	Yhl018wp
NP_011846.1	Yhl017wp
NP_011847.1	Plasma membrane transporter for both urea and polyamines, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway
NP_878085.1	Yhl015w-ap
NP_011848.1	Rps20p
NP_011849.1	Ylf2p
NP_011850.1	Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; shows cytoplasmic localization
NP_011851.1	Yhl012wp
NP_011852.1	Prs3p
NP_011853.1	Yhl010cp
NP_011854.1	Yap3p
NP_058133.1	Yhl009w-bp
NP_058134.1	Yhl009w-ap
NP_011855.1	Yhl008cp
NP_011856.1	Ste20p
NP_011857.2	Shu1p
NP_011859.1	Mrp4p
NP_011860.1	Lag1p
NP_011861.1	Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes
NP_011862.1	Rpl14bp
NP_011863.1	Osh7p
NP_011864.1	Subunit of the ubiqunol-cytochrome c oxidoreductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and comprises part of the mitochondrial respiratory chain
NP_011865.1	Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized
NP_011866.1	Yhr003cp
NP_011867.1	Nem1p
NP_011868.1	Gpa1p
NP_011869.1	Mrs11p
NP_011870.1	Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes
NP_011871.1	Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family
NP_878086.1	Yhr007c-ap
NP_011872.1	Sod2p
NP_011873.1	Yhr009cp
NP_011874.1	Rpl27ap
NP_011875.1	Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth
NP_011876.1	Vps29p
NP_011877.1	Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
NP_011878.1	Spo13p
NP_011879.1	Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export
NP_011880.1	Ysc84p
NP_011881.1	Ysc83p
NP_011882.1	Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway
NP_011883.1	Ded81p
NP_011884.1	Yhr020wp
NP_011885.1	Rps27bp
NP_011886.1	Non-essential protein of unknown function
NP_011887.1	Yhr022cp
NP_878087.1	Yhr022c-ap
NP_011888.1	Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively
NP_011889.1	Mas2p
NP_011890.1	Thr1p
NP_011891.1	Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain
NP_011892.1	Rpn1p
NP_011893.1	Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p
NP_011894.1	Yhi9p
NP_011895.1	Slt2p
NP_011896.1	Rrm3p
NP_011897.1	Yhr032wp
NP_011898.1	Yhr033wp
NP_011899.1	Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)
NP_011900.1	Yhr035wp
NP_011901.1	Essential nuclear envelope integral membrane protein identified as a suppressor of a cold-sensitive mutant of CRM1, a karyopherin; homologous to and interacts with Brr6p, which is a nuclear envelope protein involved in nuclear export
NP_011902.1	Put2p
NP_011903.1	Rrf1p
NP_011904.1	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids
NP_011905.1	Vma10p
NP_011906.1	Essential protein required for the accumulation of box C/D snoRNA
NP_011907.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance
NP_011908.1	Ncp1p
NP_011909.1	Dog2p
NP_011910.1	Dog1p
NP_011911.1	Yhr045wp
NP_011912.1	Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate
NP_011913.1	Arginine/alanine aminopeptidase, overproduction stimulates glycogen accumulation
NP_011914.1	Yhk8p
NP_011915.1	Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh2p and Fsh3p
NP_011917.1	Smf2p
NP_878088.1	Yhr050w-ap
NP_011918.1	Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels
NP_011919.1	Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles
NP_011920.1	Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
NP_011921.1	Yhr054cp
NP_011922.1	Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
NP_011923.2	Rsc30p
NP_011924.1	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway
NP_011925.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_011926.1	Protein of unknown function, required for survival upon exposure to K1 killer toxin
NP_011927.1	Vma22p
NP_011928.1	Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain
NP_011929.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
NP_011930.1	Pan5p
NP_011931.2	Ssz1p
NP_011932.2	Rrp3p
NP_011933.1	Ssf1p
NP_011934.1	Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology
NP_011935.1	Dys1p
NP_011936.1	Rrp4p
NP_011937.1	tRNA(m(1)G37)methyltransferase, methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya
NP_011938.1	Pcl5p
NP_011939.1	Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis
NP_058135.1	Nop10p
NP_011940.1	Osh3p
NP_011941.1	Qns1p
NP_011942.1	Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein
NP_011943.2	Ptc7p
NP_011944.2	Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance
NP_011945.1	Yhr078wp
NP_011946.1	Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; Kar2p binds inactive Ire1p and releases from it upon ER stress
NP_011947.2	Sae3p
NP_011948.1	Yhr080cp
NP_011949.1	Substrate-specific nuclear cofactor for exosome activity in the processing of stable RNAs; required for telomere length maintenance; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination
NP_011950.1	Nonessential putative serine/threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation
NP_011951.1	Sam35p
NP_011952.1	Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth
NP_011953.1	Ipi1p
NP_011954.1	RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA
NP_878089.1	Yhr086w-ap
NP_011955.1	Yhr087wp
NP_011956.1	Rpf1p
NP_011957.1	Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA
NP_011958.1	Yng2p
NP_011959.1	Msr1p
NP_011960.1	Hxt4p
NP_011962.1	Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
NP_011964.1	Hxt5p
NP_011965.1	Yhr097cp
NP_011966.1	Sfb3p
NP_011967.1	Tra1p
NP_011968.1	Yhr100cp
NP_011969.1	Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall beta-1,6-glucan
NP_011970.1	Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body
NP_011971.1	Sbe22p
NP_011972.1	Gre3p
NP_011973.1	Ypt35p
NP_011974.1	Trr2p
NP_011975.1	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
NP_011976.1	Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi
NP_011977.1	Cytochrome c lysine methyltransferase, trimethylates residue 72 of apo-cytochrome c (Cyc1p) in the cytosol; not required for normal respiratory growth
NP_011978.1	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport
NP_011979.1	Uba4p
NP_011980.1	Yhr112cp
NP_011981.1	Yhr113wp
NP_011982.1	SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins
NP_011983.1	Protein involved in regulating spindle position and orientation, functionally redundant with Dma2p; homolog of S. pombe Dma1 and H. sapiens Chfr
NP_011984.1	Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p
NP_011985.1	Tom71p
NP_011986.1	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p
NP_011987.1	Set1p
NP_011988.1	Msh1p
NP_011989.1	Protein of unknown function that may function in RNA processing; interacts with Pbp1p and Pbp4p and associates with ribosomes; contains an RNA-binding LSM domain and an AD domain; GFP-fusion protein is induced by the DNA-damaging agent MMS
NP_011990.1	Yhr122wp
NP_011991.1	sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability
NP_011992.1	Ndt80p
NP_011994.1	Yhr126cp
NP_011995.1	Yhr127wp
NP_011996.2	Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway
NP_011997.1	Arp1p
NP_011999.2	Yhr131cp
NP_012000.1	Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly
NP_036194.1	Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
NP_012001.1	Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins
NP_012002.1	Wss1p
NP_012003.1	Yck1p
NP_012004.1	Spl2p
NP_012005.1	Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism
NP_012006.1	Yhr138cp
NP_012007.1	Sps100p
NP_012009.1	Yhr140wp
NP_012010.1	Rpl42bp
NP_012011.1	Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER
NP_012012.1	Dse2p
NP_012013.1	Rpc10p
NP_012014.1	Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT cell cycle regulated
NP_012016.1	Protein that binds to cruciform DNA structures
NP_012017.1	Mrpl6p
NP_012018.1	Imp3p
NP_012019.1	Skg6p
NP_012020.1	Pex28p
NP_012021.1	Yhr151cp
NP_012022.1	Spo12p
NP_012023.1	Spo16p
NP_012024.1	Rtt107p
NP_012025.1	Ysp1p
NP_012026.1	Non-essential component of U5 snRNP; nuclear protein; physically interacts with Irr1p of cohesin complex; may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication
NP_012027.1	Rec104p
NP_012028.1	Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
NP_012029.1	Yhr159wp
NP_012030.1	Pex18p
NP_012031.1	Yap1801p
NP_012032.1	Yhr162wp
NP_012033.2	Sol3p
NP_012034.1	Essential tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities; required for Okazaki fragment processing; involved in DNA repair pathways; potential Cdc28p substrate
NP_012035.1	Prp8p
NP_012036.1	Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_012037.1	Thp2p
NP_012038.1	Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly
NP_012039.1	Putative ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 40S ribosomal subunit
NP_012040.1	Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex
NP_012041.1	Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation
NP_012042.1	Spc97p
NP_012044.1	Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is induced in response to glucose
NP_012045.1	Putative low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation
NP_878090.1	Yhr175w-ap
NP_012046.2	Fmo1p
NP_012047.1	Yhr177wp
NP_012048.1	Stb5p
NP_012049.1	Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism
NP_012051.1	Svp26p
NP_012052.1	Yhr182wp
NP_012053.1	Gnd1p
NP_012054.1	Ssp1p
NP_012055.1	Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation
NP_012056.1	Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors
NP_012057.1	Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin
NP_012058.1	Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Tp homolog
NP_012059.1	Pth1p
NP_012060.1	Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway
NP_012061.1	Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion
NP_012062.1	Yhr192wp
NP_012063.1	Egd2p
NP_012064.1	Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34
NP_012065.1	Nvj1p
NP_012066.1	Utp9p
NP_012067.1	Rix1p
NP_012068.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_012069.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_976247.1	Yhr199c-ap
NP_012070.1	Rpn10p
NP_012071.1	Ppx1p
NP_012072.1	Yhr202wp
NP_012073.1	Rps4bp
NP_012074.1	Mnl1p
NP_012075.1	Sch9p
NP_012076.1	Skn7p
NP_012077.1	Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus
NP_012078.1	Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
NP_012079.1	Putative S-adenosylmethionine-dependent methyltransferase; mediates cantharidin resistance
NP_012080.1	Yhr210cp
NP_012081.1	Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p
NP_878091.1	Yhr212w-ap
NP_012083.1	Yhr213wp
NP_878092.1	Yhr213w-ap
NP_878093.1	Yhr213w-bp
NP_012084.1	Yhr214wp
NP_012086.1	Yhr214c-bp
NP_036195.1	Yhr214c-cp
NP_878094.1	Yhr214c-dp
NP_878095.1	Yhr214c-ep
NP_012087.1	Pho12p
NP_012088.1	Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
NP_012090.1	Yhr218wp
NP_012091.1	Yhr219wp
NP_012311.1	Yjl225cp
NP_012312.1	Pau1p
NP_012313.1	Vth2p
NP_012314.1	Protein of unknown function, expression is induced during nitrogen limitation
NP_012316.1	Putative hexose transporter that is nearly identical to Hxt11p, has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p
NP_012317.1	Yjl218wp
NP_012318.1	Yjl217wp
NP_012319.1	Yjl216cp
NP_012321.1	Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose
NP_012322.1	Yjl213wp
NP_012323.1	Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
NP_012325.1	RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import
NP_012326.1	Mitochondrial protein that interacts with the 5'-untranslated region of the COB mRNA and has a role in its stability and translation; found in a complex at the inner membrane along with Pet309p
NP_012327.1	Nuc1p
NP_012328.1	Laa1p
NP_012329.1	Yjl206cp
NP_012330.1	Protein of unknown function, involved in secretion of proteins that lack classical secretory signal sequences
NP_012331.1	Rcy1p
NP_012332.1	Subunit of the SF3a splicing factor complex, required for spliceosome assembly
NP_012334.1	Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p
NP_012335.1	Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
NP_012337.1	Pho90p
NP_012338.1	Ubp12p
NP_012339.1	Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids
NP_012341.1	Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p
NP_012342.1	Yjl193wp
NP_012343.1	Sop4p
NP_012344.1	Rps14bp
NP_012345.1	Rps22ap
NP_012346.1	Rpl39p
NP_012348.1	Swe1p
NP_012349.1	Mnn5p
NP_012350.1	Yjl185cp
NP_012351.1	Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p
NP_012352.1	Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p
NP_012354.1	Yjl181wp
NP_012355.1	Conserved protein required for assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; mutation of human ATP12 reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency
NP_012356.1	Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin
NP_012357.2	Type II membrane protein involved in autophagy; binds phosphatidylinositol 3-phosphate, required for the cytoplasm-to-vacuole targeting (Cvt) pathway
NP_012358.1	Rpl17bp
NP_012359.1	Swi3p
NP_012361.1	Kre9p
NP_012362.1	Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
NP_012363.1	Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions
NP_012364.1	Yjl171cp
NP_012365.2	Protein that regulates signaling from a G protein beta subunit Ste4p and its relocalization within the cell; specific to a-cells and induced by alpha-factor
NP_012367.1	Set2p
NP_012368.1	Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis
NP_012369.1	Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p
NP_012370.1	Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters
NP_012371.1	cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p
NP_012372.1	Yjl163cp
NP_012373.2	Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein
NP_012374.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_012375.2	Yjl160cp
NP_012376.3	O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation
NP_012377.1	Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
NP_012378.1	Far1p
NP_012379.1	Ssy5p
NP_012380.1	Fructose-2,6-bisphosphatase, required for glucose metabolism
NP_012381.1	Vps35p
NP_012382.2	Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
NP_012384.1	Sna3p
NP_012386.1	Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C; null mutant suppresses dst1delta sensitivity for 6-azauracil
NP_012387.1	Rpa34p
NP_012388.1	Yjl147cp
NP_012389.1	Protein involved in modulation of Ime2p activity during meiosis, appears to act indirectly to promote Ime2p-mediated late meiotic functions; found in growing cells and degraded during sporulation
NP_012390.1	Sfh5p
NP_012391.1	Yjl144wp
NP_012392.1	Tim17p
NP_012394.1	Yak1p
NP_012395.1	Rpb4p
NP_012396.1	Yur1p
NP_012397.1	Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G
NP_012398.1	Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin
NP_878101.1	Yjl136w-ap
NP_012399.1	Rps21bp
NP_012401.1	Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids
NP_878102.1	Yjl133c-ap
NP_012402.1	Mrs3p
NP_012403.1	Yjl132wp
NP_012404.1	Putative protein of unknown function; the authentic non-tagged protein is detected in highly purified mitochondria; null mutant is viable, displays increased frequency of mitochondrial genome loss (petite formation)
NP_012405.1	Ura2p
NP_012406.1	Trk1p
NP_012407.1	Pbs2p
NP_878103.1	Yjl127c-bp
NP_012408.1	Spt10p
NP_012409.1	Nit2p
NP_012410.1	Subunit of tRNA (1-methyladenosine) methyltransferase, with Gcd10p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
NP_012411.1	Lsm1p
NP_012412.1	Yjl123cp
NP_012413.1	Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p
NP_012414.1	Rpe1p
NP_012417.1	Yjl118wp
NP_012418.1	Pho86p
NP_012419.1	Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family
NP_012420.1	Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed
NP_012421.1	Yjl113wp
NP_012422.1	Yjl114wp
NP_012423.1	Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats
NP_012424.1	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
NP_012425.1	Gzf3p
NP_012426.1	Utp10p
NP_012427.1	Prm10p
NP_012428.1	Yjl107cp
NP_012429.1	Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
NP_012430.1	Set4p
NP_012431.1	Pam16p
NP_012432.1	Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis
NP_012433.1	Mitochondrial elongation factor involved in translational elongation
NP_012434.1	Gsh1p
NP_012435.1	Phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
NP_012436.1	Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane
NP_012437.1	Sap185p
NP_012438.1	Protein of unknown function; homolog of mammalian PTPLA; involved in sphingolipid biosynthesis, protein trafficking; required for cell viability
NP_012439.2	Mrpl49p
NP_012440.1	Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p
NP_012441.1	Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies
NP_012442.1	Tok1p
NP_012443.1	Srs2p
NP_012444.2	Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors
NP_012445.1	Subunit of DNA Polymerase II Epsilon complex; has BRCT domain, required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis, also required for S/M checkpoint control
NP_012446.1	Sip4p
NP_012447.1	Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine
NP_012448.1	tRNA ligase, required for tRNA splicing; composed of three essential domains containing the phosphodiesterase, polynucleotide kinase, and ligase activities required for ligation; localized at the inner membrane of the nuclear envelope
NP_012450.1	Exo70p
NP_012451.1	Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p; phosphorylated in vitro by the cyclin-CDK complex, Pcl7p-Pho85p; identified as a potential Cdc28p substrate; mRNA is cell cycle regulated, peaking in M phase
NP_012452.1	Tax4p
NP_012453.1	Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_012454.1	Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
NP_012455.1	Scp160p
NP_012456.1	Pry1p
NP_012457.1	Pry3p
NP_878104.1	Yjl077w-bp
NP_012459.1	Net1p
NP_012461.1	Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member
NP_012462.1	Jem1p
NP_012463.1	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
NP_012464.1	Arg2p
NP_012465.1	Yjl070cp
NP_012466.1	Utp18p
NP_012467.1	Yjl068cp
NP_012469.1	Mpm1p
NP_012470.1	Subunit of ISW2/yCHRAC chromatin accessibility complex along with Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing
NP_012472.1	Mrpl8p
NP_076894.1	Yjl062w-ap
NP_012473.1	Las21p
NP_012474.1	Nup82p
NP_012475.1	Bna3p
NP_012476.1	Yhc3p
NP_012477.1	Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity
NP_012478.1	Putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p
NP_012479.1	Zinc-regulated transcription factor, binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc; regulates its own transcription; contains seven zinc-finger domains
NP_012480.1	Yjl055wp
NP_012481.1	Tim54p
NP_012482.1	Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport
NP_076895.1	Yjl052c-ap
NP_012483.1	Tdh1p
NP_012484.1	Irc8p
NP_012485.1	Mtr4p
NP_012486.1	Yjl049wp
NP_012487.1	Ubx6p
NP_878105.1	Yjl047c-ap
NP_012488.1	Rtt101p
NP_012489.2	Putative lipoate-protein ligase A family member; null mutant displays respiratory growth defect, decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_012490.1	Yjl045wp
NP_012491.1	Gyp6p
NP_012492.1	Yjl043wp
NP_012493.1	Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins
NP_012494.1	Nsp1p
NP_012495.1	Nup192p
NP_012496.1	Yjl038cp
NP_012497.1	Putative protein of unknown function; expression induced in respiratory-deficient cells and in carbon-limited chemostat cultures; similar to adjacent ORF, YJL038C; null mutant displays increased levels of spontaneous Rad52 foci
NP_012498.1	Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX domain; forms complex with Snx41p and Atg20p
NP_012499.1	Tad2p
NP_012500.1	Kar2p
NP_012501.1	Putative nucleolar DEAD box RNA helicase; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis
NP_012503.2	Bet4p
NP_012504.1	Mad2p
NP_012505.1	Vps53p
NP_012506.1	Yjl028wp
NP_012507.1	Yjl027cp
NP_012508.1	Rnr2p
NP_012509.1	Rrn7p
NP_012510.1	Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function
NP_012511.1	Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_012514.2	Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches
NP_012515.2	Mps3p
NP_012518.2	Yjl016wp
NP_012520.1	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
NP_012521.1	Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover
NP_012522.2	Vtc4p
NP_012523.1	Rpc17p
NP_012524.1	Nop9p
NP_012526.1	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
NP_012528.1	Ctk2p
NP_012529.1	Cyr1p
NP_012530.1	Sys1p
NP_012531.1	Mitochondrial inner membrane protein, required for assembly of cytochrome c oxidase
NP_012532.1	Ost1p
NP_012533.1	Pre3p
NP_012534.1	Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
NP_012535.1	Mpp10p
NP_012536.2	Yjr003cp
NP_012537.1	Sag1p
NP_012538.1	Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex
NP_878106.1	Yjr005c-ap
NP_012539.1	Pol31p
NP_012540.1	Sui2p
NP_012541.1	Yjr008wp
NP_012542.1	Tdh2p
NP_012543.1	Met3p
NP_012544.1	Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex
NP_012545.1	Yjr011cp
NP_012546.1	Yjr012cp
NP_012547.2	Gpi14p
NP_012548.1	Tma22p
NP_012549.1	Yjr015wp
NP_012550.1	Ilv3p
NP_012551.2	Peptidylprolyl-cis/trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNA polymerase II large subunit (Rpo21p) C-terminal domain
NP_012553.1	Tes1p
NP_012555.1	Rec107p
NP_012556.2	Lsm8p
NP_012558.1	Putative methylthio-ribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant
NP_012559.1	Bna1p
NP_012560.1	Yjr027wp
NP_012561.1	Yjr026wp
NP_012562.1	Yjr029wp
NP_012563.1	Yjr028wp
NP_012564.1	Yjr030cp
NP_012565.1	Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea2p
NP_012566.1	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity
NP_012567.1	Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate
NP_012568.1	Protein required for assembly of cytochrome c oxidase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_012569.1	Rad26p
NP_012570.1	Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability
NP_012573.1	Yjr039wp
NP_012574.1	Gef1p
NP_012575.1	Urb2p
NP_012576.1	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for assembly of the subcomplex and also for formation of the nucleocytoplasmic Gsp1p concentration gradient that plays a role in nuclear trafficking
NP_012577.1	Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p
NP_012578.1	Vps55p
NP_012579.1	Ssc1p
NP_012580.1	Tah11p
NP_012581.1	Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions
NP_012582.1	Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
NP_012583.1	Utr1p
NP_012584.1	Isy1p
NP_012585.1	Osm1p
NP_012586.1	Rad7p
NP_012587.1	Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis
NP_012588.1	Yjr054wp
NP_012589.1	Protein of unknown function, required for growth at high temperature
NP_012591.1	Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p
NP_012592.1	Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex
NP_012593.1	Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake
NP_012594.1	Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA
NP_012595.1	Yjr061wp
NP_012596.1	Nta1p
NP_012597.1	Rpa12p
NP_012598.1	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
NP_012599.1	Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity
NP_012600.1	Tor1p
NP_012601.1	Yae1p
NP_012602.1	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
NP_012603.1	Ham1p
NP_012604.1	Lia1p
NP_012606.1	Npa3p
NP_012607.1	Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis
NP_012608.1	Mog1p
NP_012609.1	Hoc1p
NP_012610.1	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
NP_012611.1	Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated
NP_012612.1	Tryptophan 2,3-dioxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
NP_012613.1	Yjr079wp
NP_012614.1	Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media
NP_012615.1	Subunit of the NuA4 acetyltransferase complex that acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3
NP_012616.1	Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in actin cytoskeleton organization; potential Cdc28p substrate
NP_012617.1	Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling
NP_012618.1	Yjr085cp
NP_012619.1	Ste18p
NP_012621.1	Yjr088cp
NP_012622.1	Essential chromosomal passenger protein involved in coordinating cell cycle events for proper chromosome segregation; C-terminal region binds Sli15p, and the middle region, upon phosphorylation, localizes Cbf2p to the spindle at anaphase
NP_012623.1	Grr1p
NP_012624.1	Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells
NP_012625.2	Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate
NP_012626.1	Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity
NP_012627.1	Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p
NP_012628.1	Rpl43bp
NP_012629.1	Sfc1p
NP_012630.1	Yjr096wp
NP_012631.1	Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein
NP_012632.1	Yjr098cp
NP_012633.1	Yuh1p
NP_012634.1	Putative protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation); similar to murine NOR1
NP_012635.1	Rsm26p
NP_012636.1	Vps25p
NP_012637.1	Ura8p
NP_012638.1	Sod1p
NP_012639.1	Ado1p
NP_012640.1	Non-essential protein of unknown function
NP_012641.1	Yjr107wp
NP_012642.1	Protein of unknown function, required for normal microtubule organization
NP_012643.1	Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor
NP_012644.1	Ymr1p
NP_012645.1	Yjr111cp
NP_012646.1	Nnf1p
NP_878107.1	Yjr112w-ap
NP_012647.1	Rsm7p
NP_012649.1	Yjr115wp
NP_012650.1	Yjr116wp
NP_012651.1	Ste24p
NP_012652.1	Protein of unknown function; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth
NP_012653.1	JmjC domain family histone demethylase specific for H3-K4 (lysine at position 4 of the histone H3 protein); removes methyl groups specifically added by Set1p methyltransferase
NP_012654.1	Yjr120wp
NP_012655.1	Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
NP_012656.1	Mitochondrial matrix protein involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins; activates the radical-SAM family members Bio2p and Lip5p; interacts with Ccr4p in the two-hybrid system
NP_012657.1	Rps5p
NP_012658.1	Yjr124cp
NP_012659.1	Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p
NP_012660.1	Vps70p
NP_012661.1	Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions
NP_012663.1	Yjr129cp
NP_012664.1	Str2p
NP_012665.1	Mns1p
NP_012666.1	Nmd5p
NP_012667.1	Xpt1p
NP_012668.1	Sgm1p
NP_012669.1	Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner
NP_058168.1	Tim8p
NP_012670.1	Yjr136cp
NP_116579.1	Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine
NP_012672.1	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane
NP_012673.1	Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions
NP_012674.1	Transcriptional corepressor involved in the cell cycle-regulated transcription of histone genes HTA1, HTB1, HHT1, and HHT2; involved in position-dependent gene silencing and nucleosome reassembly
NP_012675.1	Yjr141wp
NP_012676.1	Yjr142wp
NP_012677.1	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals
NP_012678.1	Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage
NP_012679.1	Rps4ap
NP_012681.1	Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant
NP_012682.1	Cytosolic branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during stationary phase and repressed during logarithmic phase
NP_012683.1	Yjr149wp
NP_012684.1	Dan1p
NP_012685.1	Dan4p
NP_878108.1	Yjr151w-ap
NP_012686.1	Dal5p
NP_012687.1	Pgu1p
NP_012688.1	Yjr154wp
NP_012689.1	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
NP_012690.1	Thi11p
NP_012692.1	Protein of unknown function with similarity to hexose transporter family members, expression is repressed by high levels of glucose
NP_012693.1	Sorbitol dehydrogenase; expression is induced in the presence of sorbitol
NP_012694.1	Mph3p
NP_012695.1	Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_012698.1	Putative protein of unknown function
NP_012700.1	Ykl222cp
NP_012701.1	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
NP_012702.1	Fre2p
NP_012703.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_012704.1	Sry1p
NP_012705.1	Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose
NP_012706.1	Ura1p
NP_012707.1	Ykl215cp
NP_012708.1	Yra2p
NP_012709.1	WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase
NP_012710.1	Sac1p
NP_012711.1	Trp3p
NP_012712.1	Ubiquitin activating enzyme (E1), involved in ubiquitin-mediated protein degradation and essential for viability
NP_012713.1	Ste6p
NP_012714.1	Protein involved in 5' end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p
NP_012715.3	Putative protein of unknown function; non-essential gene; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_012716.1	Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly
NP_012717.1	Nuclear pore protein involved in nuclear export of pre-tRNA
NP_012718.1	eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade
NP_012719.2	Tor2p
NP_012721.1	Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases
NP_012723.2	Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein
NP_012724.1	Pex1p
NP_012725.1	Ykt6p
NP_012726.2	Mia40p
NP_012727.1	Mst1p
NP_012728.1	Sds22p
NP_012729.1	Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p
NP_012730.1	Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p
NP_012731.1	Cnb1p
NP_012732.1	Hym1p
NP_012733.1	Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins
NP_012734.1	Ykl187cp
NP_012735.1	mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA
NP_012736.1	Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate
NP_012737.1	Spe1p
NP_878109.1	Ykl183c-ap
NP_012738.1	Protein of unknown function; gene expression increases in cultures shifted to a lower temperature
NP_012739.1	Fas1p
NP_012740.1	Prs1p
NP_012741.1	Rpl17ap
NP_012742.1	Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function
NP_012743.1	Ste3p
NP_012745.1	Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
NP_012746.1	Zrt3p
NP_012747.1	Tpo5p
NP_012748.1	Snu114p
NP_012749.1	Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles
NP_012750.1	Ykl171wp
NP_012751.1	Mrpl38p
NP_012753.2	Putative serine/threonine protein kinase with unknown cellular role
NP_012754.1	Mrp49p
NP_012755.1	cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p
NP_012756.1	Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes
NP_012757.1	Pir1p
NP_012758.1	Pir3p
NP_012760.1	Ykl162cp
NP_012761.1	Ykl161cp
NP_012762.1	Transcription elongation factor that contains a conserved zinc finger domain; implicated in the maintenance of proper chromatin structure in actively transcribed regions; deletion inhibits Brome mosaic virus (BMV) gene expression
NP_012763.1	Rcn1p
NP_012765.2	Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W
NP_012766.1	Rps27ap
NP_012767.1	Rsm22p
NP_012768.1	Srp102p
NP_012770.1	Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis
NP_012771.1	Ykl151cp
NP_012772.1	Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis
NP_012773.1	RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition
NP_012774.1	Sdh1p
NP_012776.1	Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
NP_012777.1	Rpt1p
NP_012778.1	Rpc25p
NP_012779.1	Ltv1p
NP_012780.1	Putative mitochondrial ribosomal protein, has similarity to E. coli ribosomal protein S2
NP_012781.1	Sdh3p
NP_012782.1	Tgl1p
NP_012783.1	Ctk1p
NP_690844.1	Hsk3p
NP_012784.1	Mrpl31p
NP_012785.2	Putative protein of unknown function; mutation results in growth defect on a non-fermentable (respiratory) carbon source
NP_012787.1	Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting
NP_012788.1	Oct1p
NP_012789.1	Ykl133cp
NP_012790.1	Rma1p
NP_012792.1	She2p
NP_012793.1	One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization
NP_012794.1	Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant
NP_012795.1	Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism
NP_012796.1	Ypk1p
NP_012797.1	Rrn3p
NP_012798.1	Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane
NP_012800.1	Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm
NP_012801.1	Ykl121wp
NP_012802.1	Oac1p
NP_012803.1	Vph2p
NP_012805.1	Sba1p
NP_012806.1	Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor
NP_012808.1	Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine
NP_012809.1	Rad27p
NP_012810.1	DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair
NP_012812.1	Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
NP_012813.1	Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex
NP_012814.1	Sld2p
NP_012815.1	Ykl107wp
NP_076898.1	Ykl106c-ap
NP_012816.1	Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis
NP_012817.1	Ykl105cp
NP_012818.1	Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis
NP_012819.1	Vacuolar aminopeptidase, often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway
NP_012821.1	Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p
NP_012822.1	Ykl100cp
NP_012823.2	Utp11p
NP_012824.1	Ykl098wp
NP_878110.1	Ykl096c-bp
NP_012826.1	Cwp2p
NP_012827.1	Cwp1p
NP_012828.1	Yju2p
NP_012829.1	Yju3p
NP_012830.1	Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants
NP_012831.1	GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types
NP_012832.1	Ykl091cp
NP_012833.1	Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination
NP_012834.1	Mif2p
NP_012835.1	Ykl088wp
NP_012836.1	Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1
NP_012837.1	Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxins Tsa1p and Ahp1p that are formed upon exposure to oxidants; conserved in higher eukaryotes
NP_012838.1	Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated
NP_012839.1	Mitochondrial intermembrane space protein, first component of a pathway mediating assembly of small TIM (Translocase of the Inner Membrane) complexes which escort hydrophobic inner membrane proteins en route to the TIM22 complex
NP_012841.1	Rrp14p
NP_012842.1	Translation elongation factor EF-1 gamma
NP_012843.1	Vma5p
NP_012844.1	Smy1p
NP_012845.1	Predominantly nucleolar DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis
NP_012846.1	Ykl077wp
NP_012848.1	Ykl075cp
NP_012849.1	Protein involved in early pre-mRNA splicing; component of the pre-mRNA-U1 snRNP complex, the commitment complex; interacts with Msl5p/BBP splicing factor and Sub2p; similar to metazoan splicing factor U2AF65
NP_012850.1	Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; member of the Hsp70 family; localizes to the lumen of the ER; regulated by the unfolded protein response pathway
NP_012851.1	Stb6p
NP_012852.1	Ykl071wp
NP_012853.1	Ykl070wp
NP_012854.1	Ykl069wp
NP_878111.1	Ykl068w-ap
NP_012855.1	Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup116p
NP_012856.1	Ynk1p
NP_001032580.1	Ykl065w-ap
NP_012858.1	Yet1p
NP_012859.1	Putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations
NP_012860.1	Ykl063cp
NP_012861.1	Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
NP_012862.1	Ykl061wp
NP_012863.1	Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress
NP_012864.1	Mpe1p
NP_012865.1	Toa2p
NP_012866.1	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for even distribution of NPCs around the nuclear envelope, involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p
NP_012867.1	Tma19p
NP_012868.1	Oar1p
NP_012869.1	RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex
NP_012870.1	Mitochondrial intermembrane space cysteine motif protein; mutation affects mitochondrial distribution and morphology
NP_012872.1	Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases
NP_012873.1	Sfk1p
NP_012874.1	Ykl050cp
NP_012875.2	Cse4p
NP_012876.1	Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring
NP_012877.1	Ykl047wp
NP_012878.1	Putative mannosidase, GPI-anchored membrane protein required for cell wall biosynthesis in bud formation;homologous to Dfg5p
NP_012879.1	Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair
NP_012881.1	Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate
NP_012882.1	Spc42p
NP_012883.1	Vps24p
NP_012884.1	Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria
NP_012885.2	Ptm1p
NP_012886.1	Rgt1p
NP_012887.1	Putative protein of unknown function; null mutant is viable and displays increased frequency of mitochondrial genome loss (petite formation)
NP_012889.1	Ugp1p
NP_012890.1	Tul1p
NP_012891.2	Ykl033w-ap
NP_012892.1	Ykl033wp
NP_012893.1	Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
NP_012896.1	Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids
NP_012897.1	Tfa1p
NP_012898.1	Ykl027wp
NP_012899.1	Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
NP_012900.1	Pan3p
NP_012901.1	Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP)
NP_001032581.1	Ykl023c-ap
NP_012902.1	Ykl023wp
NP_012903.1	Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation
NP_012904.1	Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats
NP_012905.1	Spt23p
NP_012906.1	Ram2p
NP_076899.1	Ykl018c-ap
NP_012907.1	Swd2p
NP_012908.1	Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities
NP_012909.1	Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
NP_012910.1	Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain
NP_012911.1	Urb1p
NP_012912.1	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
NP_012913.1	U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the formation of the second commitment complex
NP_012914.1	Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA
NP_012915.1	Ufd4p
NP_012916.1	Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus
NP_012917.1	Lac1p
NP_012918.1	Cap1p
NP_012919.1	Sft1p
NP_012920.1	Rpl14ap
NP_012921.1	Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit
NP_012922.1	Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance
NP_012923.1	Mrp17p
NP_012924.2	Did4p
NP_012925.1	Met14p
NP_012926.1	Vps1p
NP_012927.1	Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs
NP_012928.1	Osh6p
NP_012929.2	Non-essential protein of unknown function
NP_012930.2	Ykr005cp
NP_012931.2	Mrpl13p
NP_012932.1	Meh1p
NP_012933.1	Rsc4p
NP_012934.1	Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities
NP_012935.1	Tof2p
NP_012936.1	Ykr011cp
NP_012938.1	Pry2p
NP_012939.1	Ypt52p
NP_012940.1	Ykr015cp
NP_012941.1	Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media
NP_012942.1	Ykr017cp
NP_012943.1	Ykr018cp
NP_012944.1	Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentrations; Irs4p and Tax4p bind and activate the phosphatase Inp51p; mutation confers an increase in rDNA silencing
NP_012945.1	Vps51p
NP_012946.1	Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
NP_012947.1	Ntr2p
NP_012948.1	Ykr023wp
NP_012949.1	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
NP_012950.1	Rpc37p
NP_012951.1	Gcn3p
NP_012952.1	Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane
NP_012953.1	Sap190p
NP_012954.1	Set3p
NP_012955.1	Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting
NP_012956.1	Spo14p
NP_012959.1	Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p
NP_012961.1	Did2p
NP_012962.2	WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission
NP_012963.1	Spc34p
NP_012964.2	Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
NP_012965.1	General amino acid permease; localization to the plasma membrane is regulated by nitrogen source
NP_012967.1	Ykr041wp
NP_012968.2	Uth1p
NP_012969.1	Ykr043cp
NP_012970.1	Uip5p
NP_012971.2	Ykr045cp
NP_012972.1	Protein of unknown function that co-purifies with lipid particles; expression pattern suggests a role in respiratory growth; computational analysis of large-scale protein-protein interaction data suggests a role in ATP/ADP exchange
NP_012974.1	Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamics during mitosis; controls bud morphogenesis; involved in the transport of H2A and H2B histones to the nucleus
NP_012975.1	Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_012976.1	Trk2p
NP_012977.1	Ykr051wp
NP_012978.1	Mrs4p
NP_012979.1	Ysr3p
NP_012980.1	Dyn1p
NP_012981.1	Rho4p
NP_012982.2	tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair
NP_012983.1	Rps21ap
NP_012984.2	Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin
NP_012985.1	Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G
NP_012986.1	Utp30p
NP_012987.1	Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
NP_012988.1	Tfa2p
NP_012989.1	Las1p
NP_012990.1	Zinc cluster protein; regulates transcription in response to oleate levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_012991.1	Presequence translocase-associated motor subunit, required for stable complex formation between cochaperones Pam16p and Pam18p, promotes association of Pam16p-Pam18p with the presequence translocase
NP_012992.1	Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress
NP_012993.1	Gpt2p
NP_012994.1	Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex
NP_012995.1	S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis
NP_012996.1	Ykr070wp
NP_012997.1	Protein of unknown function; mutation displays synthetic lethal interaction with the pol3-13 allele of CDC2
NP_012998.1	Sis2p
NP_013000.1	Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_013001.1	Ykr075cp
NP_013002.1	Omega class glutathione transferase; not essential; similar to Ygr154cp; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
NP_013003.1	Putative transcriptional activator, that interacts with G1-specific transcription factor, MBF and G1-specific promoters; ortholog of Msa2p, an MBF and SBF activator that regulates G1-specific transcription and cell cycle initiation
NP_013004.1	Ykr078wp
NP_013005.1	tRNase Z, involved in RNA processing, has two putative nucleotide triphosphate-binding motifs (P-loop) and a conserved histidine motif, homolog of the human candidate prostate cancer susceptibility gene ELAC2
NP_013006.1	NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline
NP_013007.1	Rpf2p
NP_013008.1	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p
NP_013009.1	Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis
NP_013010.1	Hbs1p
NP_013011.1	Mrpl20p
NP_013012.1	RNA helicase in the DEAH-box family involved in the second catalytic step of splicing, exhibits ATP-dependent RNA unwinding activity
NP_013013.2	Oma1p
NP_013014.1	Tvp38p
NP_013015.1	Triacylglycerol lipase involved in triacylglycerol mobilization and degradation; found in lipid particles; potential Cdc28p substrate
NP_013016.1	Pxl1p
NP_013017.2	Srl3p
NP_013018.1	Srp40p
NP_013019.1	Ptr2p
NP_013020.1	Rpl40bp
NP_013021.1	Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs
NP_878113.2	Proposed transcription factor involved in the expression of genes regulated by alpha-factor and galactose; component of the EKC/KEOPS protein complex with Kae1p, Gon7p, Bud32p, and Cgi121p; related to human cancer-testis antigens
NP_013022.1	Ykr096wp
NP_013023.1	Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol
NP_013024.1	Ubp11p
NP_013025.1	Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes
NP_013026.2	Transmembrane protein with a role in cell wall polymer composition; localizes on the inner surface of the plasma membrane at the bud and in the daughter cell
NP_013027.1	Sir1p
NP_013028.1	Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation
NP_013029.1	Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds.
NP_013030.1	Ykr104wp
NP_013031.1	Ykr105cp
NP_013032.1	Ykr106wp
NP_013033.1	Yll067cp
NP_878115.1	Yll066w-bp
NP_013034.1	Yll066cp
NP_013037.1	Ayt1p
NP_013038.1	S-methylmethionine-homocysteine methyltransferase, functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio
NP_013039.1	Mmp1p
NP_013040.1	Gtt2p
NP_013042.1	Yll058wp
NP_013043.1	Jlp1p
NP_013044.1	Yll056cp
NP_013045.1	Yct1p
NP_013046.1	Yll054cp
NP_013047.1	Yll053cp
NP_013048.1	Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains
NP_013049.1	Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels
NP_013050.1	Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments , thought to be regulated by phosphorylation at SER4, ubiquitous and essential in eukaryotes
NP_013051.1	Protein of unknown function; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface
NP_013052.1	Ybt1p
NP_013054.1	Rnp1p
NP_013055.1	Rpl8bp
NP_013057.1	Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) family of channel proteins; involved in efflux of glycerol and in uptake of the trivalent metalloids arsenite and antimonite
NP_013058.1	E2-like conjugating enzyme that mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy
NP_013059.1	Sdh2p
NP_013060.1	Vps13p
NP_013061.1	Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats
NP_013062.1	Protein of unknown function, contains an N-terminal epsin-like domain
NP_013064.1	Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases
NP_013065.1	Protein of unknown function, required for cell growth and possibly involved in rRNA processing; mRNA is cell cycle regulated
NP_013066.1	Rix7p
NP_013067.1	Putative protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52 foci
NP_013068.1	Yll032cp
NP_013069.1	Gpi13p
NP_013071.1	Rup2p
NP_013072.1	Tpo1p
NP_013073.1	Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources
NP_013074.1	Hsp104p
NP_013075.1	Putative protein of unknown function; YLL025W is not an essential gene
NP_013076.1	Ssa2p
NP_013077.1	Yll023cp
NP_013078.1	Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized to the nucleus; has a role in telomeric silencing
NP_013079.1	Spa2p
NP_013081.1	Nonessential putative protein kinase of unknown cellular role; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues
NP_013082.1	Protein required for cytochrome c oxidase assembly, located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase
NP_013083.1	Dps1p
NP_013086.1	Bpt1p
NP_013087.1	Yll014wp
NP_013088.1	Puf3p
NP_013089.1	Yeh1p
NP_013090.1	Sof1p
NP_013091.1	Psr1p
NP_013092.1	Cox17p
NP_013093.1	Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles
NP_013094.1	Yll007cp
NP_878116.1	Yll006w-ap
NP_013095.1	Mmm1p
NP_013096.1	Spo75p
NP_013097.1	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
NP_013098.1	Sfi1p
NP_013099.1	Rtt109p
NP_013100.1	Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology, assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis
NP_013101.1	Ylr001cp
NP_013102.1	Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport; also binds to chromatin to promote the association of DNA replication factors and replication initiation
NP_013103.1	Ylr003cp
NP_013104.1	Thi73p
NP_013105.1	Ssl1p
NP_013106.1	Ssk1p
NP_013107.1	Nse1p
NP_013108.1	Pam18p
NP_013109.1	Rlp24p
NP_013110.1	Ten1p
NP_013111.1	Lot6p
NP_013112.2	Ylr012cp
NP_013113.1	Protein containing GATA family zinc finger motifs
NP_013114.1	Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p
NP_013115.1	Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; involved in telomere maintenance; similar to trithorax-group protein ASH2L
NP_013116.1	Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p
NP_013117.1	Meu1p
NP_013118.1	Pom34p
NP_013119.1	Psr2p
NP_013120.1	Yeh2p
NP_013121.1	Irc25p
NP_013122.1	Sdo1p
NP_013123.1	Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity
NP_013124.1	Ubr2p
NP_013125.1	Snf7p
NP_013126.1	cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, binds at least 9 SNARE proteins
NP_013127.2	Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells
NP_013128.1	Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine
NP_013129.1	Rpl15ap
NP_013130.1	Ylr030wp
NP_013131.1	Ylr031wp
NP_013132.1	Rad5p
NP_013133.1	Rsc58p
NP_013134.1	Smf3p
NP_013135.1	Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination; forms a complex with Mlh1p
NP_013136.1	Ylr035c-ap
NP_013137.1	Ylr036cp
NP_013138.1	Dan2p
NP_013139.1	Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated
NP_013140.1	Ric1p
NP_013141.1	Ylr040cp
NP_013143.1	Ylr042cp
NP_013144.1	Trx1p
NP_013145.1	Pdc1p
NP_013146.1	Stu2p
NP_013147.1	Rla1p
NP_013148.1	Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p
NP_013149.1	Rps0bp
NP_013150.1	Ylr049cp
NP_013151.1	Ylr050cp
NP_013152.1	Fcf2p
NP_013153.1	Subunit of the INO80 chromatin remodeling complex
NP_013154.1	Ylr053cp
NP_013155.2	Protein of unknown function proposed to be involved in the assembly of the spore wall
NP_013156.1	Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters
NP_013157.1	Erg3p
NP_013158.1	Ylr057wp
NP_013159.1	Shm2p
NP_013160.1	Rex2p
NP_013161.1	Frs1p
NP_013162.1	Rpl22ap
NP_013164.1	Ylr063wp
NP_013165.1	Ylr064wp
NP_013166.1	Ylr065cp
NP_013167.1	Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23
NP_013168.1	Specific translational activator for the COX1 mRNA, also influences stability of intron-containing COX1 primary transcripts; located in the mitochondrial inner membrane
NP_013169.1	Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in processing the 35S rRNA primary transcript to generate the 20S and 27SA2 pre-rRNA transcripts
NP_013170.1	Mitochondrial elongation factor involved in translational elongation
NP_013171.1	Xylitol dehydrogenase, converts xylitol to D-xylulose in the endogenous xylose utilization pathway
NP_013172.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation
NP_013173.1	Ylr072wp
NP_013174.1	Ylr073cp
NP_013175.1	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_013176.1	Rpl10p
NP_013178.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_013179.1	v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi
NP_013180.1	Sic1p
NP_013181.1	Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport
NP_013182.1	Galactose permease, required for utilization of galactose; also able to transport glucose
NP_013183.1	Srl2p
NP_013184.1	Protein whose 24kDa cleavage product is found in endosome-enriched membrane fractions, predicted to be a transmembrane protein
NP_013185.1	Rax2p
NP_013186.1	Arp6p
NP_013187.1	Subunit of the condensin complex, which reorganizes chromosomes during cell division, forms a stable complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity and promotes knotting of circular DNA; potential Cdc28p substrate
NP_013188.1	Protein required for fermentation at low temperature; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_013189.1	Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anchoring signal and attaches GPI to proteins in the ER
NP_013190.1	Putative alanine transaminase (glutamic pyruvic transaminase); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_013191.1	Xdj1p
NP_013192.1	Ylr091wp
NP_013193.1	Sul2p
NP_013194.2	v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane
NP_013196.1	Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif
NP_013197.1	Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin1p
NP_013198.1	Putative SCF-ubiquitin ligase F-box protein, based on both genetic and physical interactions and sequence similarity; identified in association with Cdc53p, Skp1p and Ubi4 in large and small-scale studies
NP_013199.1	DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain
NP_013200.1	Protein of unknown function, null mutation leads to an increase in sensitivity to Calcofluor white; expression of the gene is induced in the presence of isooctane
NP_076901.1	Ylr099w-ap
NP_013201.1	Erg27p
NP_013203.1	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_013204.1	DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes
NP_013205.1	Ylr104wp
NP_013206.1	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease
NP_013207.1	Mdn1p
NP_013208.1	Rex3p
NP_013209.1	Ylr108cp
NP_013210.1	Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
NP_013211.1	Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
NP_013214.1	Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p
NP_013215.1	Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms
NP_013216.1	Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein.
NP_013217.1	Msl5p
NP_013218.1	Essential splicesome assembly factor; contains multiple tetratricopeptide repeat (TPR) protein-binding motifs and interacts specifically with many spliceosome components, may serve as a scaffold during splicesome assembly
NP_013219.1	Ylr118cp
NP_013220.1	Srn2p
NP_013221.1	Yps1p
NP_013222.1	Yps3p
NP_013226.1	Ylr125wp
NP_013227.1	Ylr126cp
NP_013228.1	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; similar to cullin Cdc53p
NP_013229.1	Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain
NP_013230.1	Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex
NP_013231.1	Zrt2p
NP_013232.1	Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate
NP_013233.1	Ylr132cp
NP_013234.1	Cki1p
NP_013235.1	Pdc5p
NP_013236.1	Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p
NP_013237.1	mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis
NP_013238.1	Ylr137wp
NP_013239.1	Nha1p
NP_013240.1	Sls1p
NP_013242.1	Rrn5p
NP_013243.1	Put1p
NP_013244.1	Ylr143wp
NP_013245.1	Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly
NP_013246.1	Subunit of RNase MRP, which processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; unlike most subunits, not shared between RNase MRP and nuclear RNase P
NP_013247.1	Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid
NP_001032582.1	Ylr146w-ap
NP_013248.1	Smd3p
NP_013249.1	Pep3p
NP_013250.1	Ylr149cp
NP_013251.1	Stm1p
NP_013252.1	Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids
NP_013253.1	Ylr152cp
NP_013254.1	Acs2p
NP_013255.1	Rnh203p
NP_690845.1	Tar1p
NP_878121.1	Ylr154c-gp
NP_878122.1	Ylr154c-hp
NP_013256.1	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
NP_757337.1	Ylr156wp
NP_878123.1	Ylr156c-ap
NP_013258.1	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
NP_878124.1	Ylr157w-dp
NP_058169.1	Ylr157c-bp
NP_058170.1	Ylr157c-ap
NP_878125.1	Ylr157w-ep
NP_878126.1	Ylr157c-cp
NP_013259.1	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
NP_757338.1	Ylr159wp
NP_878127.1	Ylr159c-ap
NP_013261.1	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
NP_757339.1	Ylr161wp
NP_013263.1	Ylr162wp
NP_878128.1	Ylr162w-ap
NP_013264.1	Smaller subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins
NP_013265.1	Ylr164wp
NP_013266.1	Pus5p
NP_013267.1	Sec10p
NP_013268.1	Rps31p
NP_013269.1	Putative protein of unknown function that may be involved in intramitochondrial sorting; similar to Ups1p and to human PRELI; GFP-tagged protein localizes to mitochondria; required for wild-type respiratory growth
NP_013271.1	Small subunit of the clathrin-associated adaptor complex AP-1, which is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex
NP_013273.1	Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm
NP_013274.1	Ylr173wp
NP_013275.1	Idp2p
NP_013276.1	Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2
NP_013277.1	Rfx1p
NP_013278.1	Ylr177wp
NP_013279.1	Tfs1p
NP_013280.1	Ylr179cp
NP_013281.1	Sam1p
NP_013282.1	Vta1p
NP_013283.1	Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate
NP_013284.1	Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
NP_013286.1	Rpl37ap
NP_013287.1	Protein required for the maturation of the 18S rRNA and for 40S ribosome production; associated with spindle/microtubules; nuclear localization depends on physical interaction with Nop14p; may bind snoRNAs
NP_013288.1	Skg3p
NP_013289.1	Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress
NP_013290.1	UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids, involved in autophagy
NP_013291.1	Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p
NP_013292.1	Pex13p
NP_013293.1	Hcr1p
NP_013294.1	Ups1p
NP_013295.1	Ylr194cp
NP_013296.1	Nmt1p
NP_013297.1	Pwp1p
NP_013298.1	Sik1p
NP_013300.2	Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly
NP_013301.1	Yke2p
NP_013302.1	Protein required for ubiquinone (coenzyme Q) biosynthesis and respiratory growth; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes
NP_013304.1	Nuclear encoded protein required for translation of COX1 mRNA; binds to Cox1 protein
NP_013305.1	Qri5p
NP_013306.2	Hmx1p
NP_013307.1	Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus
NP_013308.1	Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD), forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events
NP_013309.1	Sec13p
NP_013310.1	Purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides; involved in the nicotinamide riboside salvage pathway
NP_013311.1	Clb4p
NP_013312.2	Ylr211cp
NP_013313.1	Tub4p
NP_013314.1	Putative glycoside hydrolase of the spore wall envelope; required for normal spore wall assembly, possibly for cross-linking between the glucan and chitosan layers; expressed during sporulation
NP_013315.1	Fre1p
NP_013316.1	Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein
NP_013317.1	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity
NP_013319.1	Ylr218cp
NP_013320.1	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate
NP_013321.1	Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack the ortholog of mammalian frataxin, by preventing mitochondrial iron accumulation
NP_013322.1	Rsa3p
NP_013323.1	Utp13p
NP_013324.1	Ifh1p
NP_013325.1	Ylr224wp
NP_013326.1	Ylr225cp
NP_013327.1	Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II
NP_013328.1	Structural component of the meiotic outer plaque, which is a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane
NP_058171.1	Ylr227w-bp
NP_058172.1	Ylr227w-ap
NP_013329.1	Sterol regulatory element binding protein, regulates transcription of the sterol biosynthetic genes ERG2 and ERG3; member of the fungus-specific Zn[2]-Cys[6] binuclear cluster family of transcription factors; homologous to Upc2p
NP_013330.1	Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins
NP_013332.1	Kynureninase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
NP_013334.1	TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the telomerase holoenzyme, has a possible role in activating Est2p-TLC1-RNA bound to the telomere
NP_013335.1	Top3p
NP_013338.1	Thi7p
NP_013339.1	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p substrate
NP_013340.1	Lipoyl ligase, involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups
NP_013341.1	Vps34p
NP_013342.1	Ylr241wp
NP_013343.1	Protein required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein
NP_013344.1	Ylr243wp
NP_013345.1	Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p
NP_013346.1	Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm
NP_013347.1	Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole
NP_013348.1	Putative helicase; localized to mitochondria and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52 foci
NP_013349.1	Rck2p
NP_013350.1	Yef3p
NP_013351.1	Ssp120p
NP_013352.1	Sym1p
NP_013354.1	Ylr253wp
NP_013355.1	Ndl1p
NP_013357.1	Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus
NP_058173.1	Ylr256w-ap
NP_013358.1	Ylr257wp
NP_013359.1	Gsy2p
NP_013360.1	Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated
NP_013361.1	Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules
NP_013363.1	Ypt6p
NP_013364.1	Tma7p
NP_013365.1	Red1p
NP_013366.1	Rps28bp
NP_878129.1	Ylr264c-ap
NP_013367.1	Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p
NP_013368.1	Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon
NP_013369.1	Protein of unknown function, overproduction suppresses a pam1 slv3 double null mutation
NP_013370.1	Sec22p
NP_013372.1	Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p
NP_013373.1	Ylr271wp
NP_013374.1	Ycs4p
NP_013375.1	Putative targeting subunit for the type-1 protein phosphatase Glc7p that tethers it to the Gsy2p glycogen synthase
NP_013376.1	Mcm5p
NP_013377.1	Smd2p
NP_013378.1	Dbp9p
NP_013379.1	Ysh1p
NP_013380.1	Zinc-cluster protein; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; mutant shows moderate growth defect on caffeine; YLR278C is not an essential gene
NP_013383.1	Ylr281cp
NP_013385.1	Ylr283wp
NP_013386.1	Peroxisomal delta3,delta2-enoyl-CoA isomerase, hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced
NP_013387.1	Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination
NP_878130.1	Ylr285c-ap
NP_013388.1	Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p
NP_013389.1	Ylr287cp
NP_013390.1	Rps30ap
NP_013391.1	Mec3p
NP_013392.1	Mitochondrial GTPase of unknown function, similar to E. coli elongation factor-type GTP-binding protein LepA and to LK1236.1 from Caenorhabditis elegans
NP_013393.1	Ylr290cp
NP_013394.1	Gcd7p
NP_013395.1	Sec72p
NP_013396.1	Gsp1p
NP_013398.1	Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
NP_013400.1	Ylr297wp
NP_013401.1	Yhc1p
NP_013402.1	Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation
NP_013403.1	Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes
NP_013404.1	Ylr301wp
NP_013406.1	Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase), required for sulfur amino acid synthesis
NP_013407.1	Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy
NP_013408.1	Stt4p
NP_013409.1	Ubc12p
NP_013410.1	Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall
NP_878131.1	Ylr307c-ap
NP_013411.1	Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall
NP_013412.1	Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi
NP_013413.1	Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1
NP_013415.1	Qnq1p
NP_013416.2	Mrpl15p
NP_013417.2	Sph1p
NP_013418.1	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
NP_013419.1	Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p- Nkp1p-Nkp2p-Ame1p-Mtw1p)
NP_013420.2	Tad3p
NP_013422.1	Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia
NP_013423.1	Bud6p
NP_013424.1	Protein involved in resistance to ionizing radiation; acts with Mms1p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks
NP_013425.1	Sfh1p
NP_013427.1	Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p
NP_013428.1	Pex30p
NP_013429.1	Rpl38p
NP_013431.1	Tma10p
NP_013432.1	Nma1p
NP_013433.2	Rec102p
NP_013434.1	Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane
NP_013436.1	O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p
NP_013437.1	Rps25bp
NP_013439.1	Nup2p
NP_013440.1	Sgd1p
NP_013441.1	Vrp1p
NP_013444.1	Rpp0p
NP_013445.1	Spo77p
NP_013446.1	Fks1p
NP_878133.1	Ylr342w-ap
NP_013447.1	Gas2p
NP_013448.1	Rpl26ap
NP_013449.1	Ylr345wp
NP_013450.1	Ylr346cp
NP_013451.1	Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p) that mediates nuclear import of cargo proteins via a nuclear localization signal (NLS), interacts with nucleoporins to guide transport across the nuclear pore complex
NP_013452.1	Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
NP_013454.1	Orm2p
NP_013455.1	Nit3p
NP_013456.1	Ylr352wp
NP_013457.1	Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole
NP_013458.1	Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate
NP_013459.1	Ilv5p
NP_013460.1	Ylr356wp
NP_013461.1	Rsc2p
NP_013463.1	Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency
NP_013464.1	Vps38p
NP_013465.1	Phosphoesterase involved in downregulation of the unfolded protein response, at least in part via dephosphorylation of Ire1p; dosage-dependent positive regulator of the G1/S phase transition through control of the timing of START
NP_878134.1	Ylr361c-ap
NP_013466.1	Ste11p
NP_013467.1	Protein interacting with Nam7p, may be involved in the nonsense-mediated mRNA decay pathway
NP_076903.1	Ylr363w-ap
NP_013468.1	Ylr364wp
NP_013471.1	Rps22bp
NP_013472.1	Mdm30p
NP_013473.1	Ssq1p
NP_013474.1	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
NP_013475.1	Rom2p
NP_013476.1	Sur4p
NP_013477.1	Vid22p
NP_013479.1	Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids
NP_013480.1	Psy3p
NP_013481.1	Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism
NP_013482.1	Sec61p
NP_013484.1	Phosphatidylinositol transfer protein with a potential role in lipid turnover; interacts specifically with thioredoxin peroxidase (Tsa2p) and may have a role in oxidative stress resistance
NP_013485.1	Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules
NP_013486.1	Nam2p
NP_013487.1	Smc6p
NP_013488.1	Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)
NP_013489.1	Swc7p
NP_013490.1	Vac14p
NP_013491.1	Reh1p
NP_013492.1	Rps29ap
NP_013493.2	Ste23p
NP_013494.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_013495.1	Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall
NP_013496.1	Ylr392cp
NP_013497.1	Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, interacts genetically with ATP6
NP_013498.1	SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate
NP_013499.1	Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
NP_013500.1	Vps33p
NP_013501.1	Afg2p
NP_013502.1	Ski2p
NP_013503.1	Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p
NP_013505.2	Dus3p
NP_013507.1	Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, involved in cell size modulation
NP_013508.1	Seipin protein involved in lipid droplet morphology; null mutants form lipid droplet clusters, especially in stationary phase, which appear to bud chaotically from the ER; corresponding gene in humans (BSCL2) causes lipodystrophy
NP_013509.1	Dus4p
NP_013510.1	Rpl31bp
NP_878135.1	Ylr406c-ap
NP_013511.1	Ylr407wp
NP_013512.1	Ylr408cp
NP_013513.1	Utp21p
NP_013514.1	Vip1p
NP_058174.1	Ylr410w-bp
NP_058175.1	Ylr410w-ap
NP_013515.1	High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae
NP_013516.1	Ylr412wp
NP_878136.1	Ylr412c-ap
NP_013517.1	Ylr413wp
NP_013518.1	Ylr414cp
NP_013519.1	Ylr415cp
NP_013521.1	Vps36p
NP_013522.1	Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for expression of certain genes, modification of some histones, and telomere maintenance
NP_013523.1	Ylr419wp
NP_013524.1	Ura4p
NP_013525.1	Subunit of the 19S regulatory particle of the 26S proteasome lid
NP_013526.1	Ylr422wp
NP_013527.1	Scaffold potein responsible for pre-autophagosomal structure organization; interacts with and is required for activation of Apg1p protein kinase; involved in autophagy but not in the Cvt (cytoplasm to vacuole targeting) pathway
NP_013528.1	Spp382p
NP_013529.1	Tus1p
NP_013530.1	Ylr426wp
NP_013531.1	Mag2p
NP_013533.1	Crn1p
NP_013534.1	Sen1p
NP_013535.1	Peripheral membrane protein, required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway
NP_013536.1	Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
NP_013537.1	Cna1p
NP_013539.2	Tsr2p
NP_013540.1	Non-essential protein of unknown function
NP_013541.1	Ylr437cp
NP_013542.1	L-ornithine transaminase (OTAse), catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive
NP_013543.1	Lsm3p
NP_013544.1	Mrpl4p
NP_013545.1	Sec39p
NP_013546.1	Rps1ap
NP_013547.1	Sir3p
NP_013548.1	Non-essential protein of unknown function
NP_013550.2	Ylr445wp
NP_013551.1	Ylr446wp
NP_013552.1	Vma6p
NP_013553.1	Rpl6bp
NP_013554.1	Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones
NP_013555.1	One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks
NP_013556.1	Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis
NP_013557.1	Sst2p
NP_013558.1	Rif2p
NP_013559.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_013560.1	Ylr455wp
NP_013561.1	Ylr456wp
NP_013562.1	Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex
NP_013564.1	Gab1p
NP_013565.1	Ylr460cp
NP_013566.1	Pau4p
NP_013567.1	Ylr462wp
NP_013569.1	Ylr464wp
NP_013571.1	Yrf1-4p
NP_878137.1	Ylr466c-bp
NP_013572.1	Yrf1-5p
NP_013573.1	Yml133cp
NP_013574.1	Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_013575.1	Yml131wp
NP_013576.1	Thiol oxidase required for oxidative protein folding in the endoplasmic reticulum
NP_013577.1	Mitochondrial membrane protein, involved in translational regulation of Cox1p and assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes
NP_013578.1	Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated
NP_013579.1	Rsc9p
NP_013580.1	Erg13p
NP_013581.1	Pga3p
NP_013582.1	Tub3p
NP_013583.1	Pho84p
NP_013585.1	Gtr1p
NP_013586.1	Ndi1p
NP_013587.1	Yml119wp
NP_013588.1	Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p
NP_013589.1	Putative RNA-binding protein, based on computational analysis of large-scale protein-protein interaction data
NP_013591.1	Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide
NP_013592.1	Van1p
NP_013593.1	Taf8p
NP_013594.1	Dat1p
NP_013595.1	Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing
NP_013596.1	Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1
NP_013597.1	Coq5p
NP_013598.1	Zds2p
NP_013599.1	Yml108wp
NP_013600.2	Protein required for nuclear retention of unspliced pre-mRNAs along with Mlp1p and Pml1p; anchored to nuclear pore complex via Mlp1p and Mlp2p; found with the subset of nuclear pores farthest from the nucleolus; may interact with ribosomes
NP_013601.1	Ura5p
NP_013602.1	Subunit of the signal recognition particle (SRP), involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19
NP_013603.1	Mdm1p
NP_013604.1	Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p
NP_013605.1	Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans
NP_013607.1	Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination
NP_878138.1	Yml100w-ap
NP_013608.1	Tsl1p
NP_013610.1	Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p
NP_013611.1	Taf13p
NP_013612.1	Vps9p
NP_013613.1	Yml096wp
NP_013614.1	Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein
NP_013616.1	Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
NP_013617.1	Utp14p
NP_013618.1	Pre8p
NP_013619.1	Rpm2p
NP_013622.1	Ufo1p
NP_013623.1	Putative protein of unknown function; null mutant displays increased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_013624.1	D-Arabinono-1,4-lactone oxidase, catalyzes the final step in biosynthesis of D-erythroascorbic acid, which is protective against oxidative stress
NP_013625.1	Tub1p
NP_013627.1	Yml083cp
NP_013628.1	Yml082wp
NP_013629.1	Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms
NP_013630.1	Yml081wp
NP_013631.1	Dus1p
NP_013632.1	Yml079wp
NP_013633.1	Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria
NP_013634.1	Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi
NP_013635.1	War1p
NP_013636.1	One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae
NP_013637.1	Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p
NP_013638.1	Rpl6ap
NP_013639.1	Tcb3p
NP_013640.1	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_013641.1	Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation
NP_013642.1	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Pol II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure; interacts with DNA polymerase alpha (Pol1p)
NP_013643.1	Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins
NP_013644.1	Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein
NP_013645.1	Sma2p
NP_013646.1	Orc1p
NP_013647.1	Tem1p
NP_013648.1	Rps1bp
NP_013649.1	Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance
NP_013650.1	Pif1p
NP_013651.1	Ogg1p
NP_013652.1	Serine esterase that deacylates exogenous lysophospholipids, homolog of human neuropathy target esterase (NTE); mammalian NTE1 deacylates phosphatidylcholine to glycerophosphocholine
NP_219498.1	Protein involved in the Mec1p-mediated checkpoint pathway that responds to DNA damage or replication arrest, transcription is induced by DNA damage
NP_013653.1	Sml1p
NP_013655.1	Cmp2p
NP_013656.1	Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
NP_013657.1	Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC25
NP_013658.1	Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions
NP_878139.1	Yml054c-ap
NP_013659.1	Yml053cp
NP_013660.1	Sur7p
NP_013661.1	Transcriptional regulator involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding
NP_013662.1	Putative protein of unknown function; non-essential gene; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_013663.1	Rse1p
NP_013664.1	Gsf2p
NP_013666.1	Prm6p
NP_013667.1	U1 snRNP protein involved in splicing, contains multiple tetriatricopeptide repeats
NP_013668.1	Yml045wp
NP_058176.1	Yml045w-ap
NP_013669.1	Rrn11p
NP_013670.1	Cat2p
NP_013671.1	Vps71p
NP_013672.1	Yml039wp
NP_013673.1	Yml040wp
NP_013674.1	Ymd8p
NP_013675.1	Yml037cp
NP_013676.2	Protein involved in telomere uncapping and elongation as component of the KEOPS protein complex with Bud32p, Kae1p, Pcc1p, and Gon7p; also shown to be a component of the EKC protein complex; homolog of human CGI-121
NP_013677.1	Amd1p
NP_013679.1	Src1p
NP_013680.2	Rad52p
NP_013681.1	Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II
NP_013682.1	Putative protein of unknown function; GFP-fusion protein localizes to mitochondria; null mutant is viable and displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth rate in minimal glycerol media
NP_013683.1	Usa1p
NP_013684.1	Ubiquitous housekeeping thioredoxin peroxidase, reduces reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; mediates redox regulation of the nuclear localization of Yap1p; deletion results in mutator phenotype
NP_013685.1	Yox1p
NP_013686.1	Rps18bp
NP_013687.1	Yml6p
NP_013688.1	Rps17ap
NP_013689.1	Nse5p
NP_013690.1	Apt1p
NP_013691.1	Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus
NP_013692.1	Yml020wp
NP_013693.1	Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p
NP_013694.1	Yml018cp
NP_013695.2	Psp2p
NP_013696.1	Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance
NP_013697.1	Taf11p
NP_013698.1	tRNA methyltransferase, catalyzes the esterification of modified uridine nucleotides in tRNAs, creating 5-methylcarbonylmethyluridine in tRNA(Arg3) and 5-methylcarbonylmethyl-2-thiouridine in tRNA(Glu); may have a role in stress response
NP_013699.1	Ubx2p
NP_013701.1	Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport
NP_013702.1	Rad33p
NP_013703.1	Spt5p
NP_013705.1	Mrpl39p
NP_013706.1	Erg6p
NP_076904.1	Yml007c-ap
NP_013707.1	Yap1p
NP_013708.1	Gis4p
NP_013709.1	Trm12p
NP_013710.1	Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress
NP_013711.1	Yml003wp
NP_013712.1	Yml002wp
NP_013713.1	Ypt7p
NP_013714.1	Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate
NP_878140.1	Ymr001c-ap
NP_013715.1	Mitochondrial intermembrane space cysteine motif protein; MIC17 is not an essential gene
NP_013716.1	Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_013717.1	Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole
NP_013718.1	Taf4p
NP_013719.1	Plb2p
NP_013721.1	Plb1p
NP_013722.1	Adi1p
NP_013723.1	Ymr010wp
NP_013724.1	Hxt2p
NP_013725.1	eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant
NP_013726.1	Sec59p
NP_013727.1	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_013728.1	Erg5p
NP_013729.1	Sok2p
NP_013730.1	Spo20p
NP_013731.1	Ymr018wp
NP_013732.1	Stb4p
NP_013733.1	Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis
NP_013734.1	Mac1p
NP_013735.1	Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly
NP_013736.1	Mss1p
NP_013737.1	Mrpl3p
NP_013738.1	Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling
NP_013739.1	Pex12p
NP_013740.1	Ymr027wp
NP_013741.1	Tap42p
NP_013742.1	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far9p, Far10p, and Far11p
NP_013743.1	Rsf1p
NP_013744.1	Ymr031cp
NP_013746.1	Hof1p
NP_878141.1	Ymr030w-ap
NP_013747.1	Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation
NP_013748.1	Ymr034cp
NP_013749.1	Imp2p
NP_013750.1	Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25
NP_013751.1	Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
NP_013752.1	Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation
NP_013753.1	Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations
NP_013754.1	Yet2p
NP_013755.1	NAD-dependent arabinose dehydrogenase, involved in biosynthesis of erythroascorbic acid; similar to plant L-galactose dehydrogenase
NP_013756.1	Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p
NP_013757.1	Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes
NP_013758.1	Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PWWP motif
NP_013759.1	Ymr045cp
NP_013760.1	Ymr046cp
NP_013762.1	Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p
NP_013763.1	Protein required for accurate chromosome segregation during meiosis
NP_013764.1	Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
NP_013765.1	Ymr050cp
NP_013766.1	Ymr051cp
NP_013767.1	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far7p, Far8p, Far9p, Far10p, and Far11p
NP_013769.1	Stb2p
NP_013770.1	Subunit a of the vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole
NP_013771.1	Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage
NP_013772.1	Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; Aac1p is a minor isoform while Pet9p is the major ADP/ATP translocator
NP_013774.1	Fet3p
NP_013775.2	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p
NP_013776.1	Sam37p
NP_013777.1	Rna14p
NP_013778.1	Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine
NP_013779.1	Rim9p
NP_013780.1	Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase
NP_013781.1	Protein required for nuclear membrane fusion during karyogamy, localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; expression of the gene is regulated by pheromone
NP_013782.1	Sov1p
NP_013783.1	Ubx4p
NP_013784.1	Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth
NP_013785.1	Nat4p
NP_013786.1	Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes
NP_013787.1	Tvp18p
NP_013788.1	Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation
NP_013789.1	Putative protein of unknown function; proposed to be involved in resistance to carboplatin and cisplatin; shares similarity to a human cytochrome oxidoreductase; null mutant displays increased levels of spontaneous Rad52 foci
NP_013790.1	Ymr074cp
NP_013791.1	Rco1p
NP_013793.1	Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes in an interdependent manner, may function as a protein-protein interaction scaffold
NP_013794.1	Vps20p
NP_013795.1	Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint
NP_013796.1	Sec14p
NP_013797.1	Nam7p
NP_013798.1	Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant
NP_013800.1	Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
NP_013801.1	Ymr084wp
NP_013802.1	Ymr085wp
NP_013803.1	Ymr086wp
NP_013805.1	Ymr087wp
NP_013806.1	Vba1p
NP_013807.1	Yta12p
NP_013808.1	Ymr090wp
NP_013809.1	Npl6p
NP_013810.1	Aip1p
NP_013811.1	Utp15p
NP_013812.1	Subunit of the CBF3 complex, which binds to the CDE III element of centromeres, bending the DNA upon binding, and may be involved in sister chromatid cohesion during mitosis
NP_013813.1	Sno1p
NP_013814.1	Snz1p
NP_013815.1	Peripheral GTPase of the mitochondrial inner membrane, essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals
NP_013816.1	Protein of unknown function; non-tagged protein is detected in highly purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_013817.1	Ymr099cp
NP_013818.1	Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene
NP_013819.1	Srt1p
NP_013820.1	Ymr102cp
NP_013822.1	Ypk2p
NP_013823.1	Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase
NP_878142.1	Ymr105w-ap
NP_013824.1	Yku80p
NP_013825.1	Spg4p
NP_013826.1	Ilv2p
NP_013827.1	One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization
NP_013828.1	Putative fatty aldehyde dehydrogenase, located in the mitochondrial outer membrane and also in lipid particles; has similarity to human fatty aldehyde dehydrogenase (FALDH) which is implicated in Sjogren-Larsson syndrome
NP_013829.1	Ymr111cp
NP_013830.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential protein
NP_013831.1	Fol3p
NP_013832.1	Ymr114cp
NP_013833.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_013834.1	G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation
NP_013835.1	Spc24p
NP_013836.1	Ymr118cp
NP_013837.1	Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals
NP_013839.1	Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine
NP_013840.1	Rpl15bp
NP_061493.1	Ymr122w-ap
NP_013842.1	V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin
NP_013843.1	Ymr124wp
NP_013844.2	Sto1p
NP_013845.1	Protein of unknown function, mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA)
NP_013846.1	Sas2p
NP_013847.1	Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis
NP_013848.1	Pom152p
NP_013849.1	Ymr130wp
NP_013850.1	Rrb1p
NP_013851.1	Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)
NP_013852.1	Rec114p
NP_013853.1	Protein that binds to and regulates Erg25p; localized to the ER; null mutant is viable in a respiratory defective background; synthetic lethal with mmt1 and mmt2 mutations; highly conserved in ascomycetes
NP_013854.1	Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p; dosage-dependent regulator of START
NP_013856.1	Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine
NP_013857.1	Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation
NP_013858.1	GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
NP_013859.1	Rim11p
NP_013860.1	Sip5p
NP_013862.1	Rpl13bp
NP_013863.2	Rps16ap
NP_013864.1	Ymr144wp
NP_013865.1	Nde1p
NP_013866.1	Tif34p
NP_013867.1	Ymr147wp
NP_013868.1	Ymr148wp
NP_013869.1	Swp1p
NP_013870.1	Imp1p
NP_013872.1	Yim1p
NP_013873.1	Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex
NP_013875.1	Rim13p
NP_013876.1	Ymr155wp
NP_013877.1	Tpp1p
NP_013878.1	Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media
NP_013879.1	Mrps8p
NP_013880.1	Ymr158c-ap
NP_013882.1	Protein that interacts with the Atg12p-Atg5p conjugate during formation of the pre-autophagosomal structure; essential for autophagy
NP_013883.1	Ymr160wp
NP_013884.1	Hlj1p
NP_013885.1	Dnf3p
NP_013886.1	Peroxisome-specific receptor important for peroxisome inheritance; co-fractionates with peroxisome membranes and co-localizes with peroxisomes in vivo; physically interacts with the myosin V motor Myo2p; INP2 is not an essential gene
NP_013887.1	Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals
NP_013888.1	Pah1p
NP_013889.1	Ymr166cp
NP_013890.1	Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer
NP_013891.1	Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain
NP_013892.1	Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose
NP_013893.1	Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p
NP_013894.1	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to endosomes; mRNA is targeted to the bud via the mRNA transport system involving She2p: YMR171C is not an essential gene
NP_013895.1	Transcription factor required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p
NP_013897.1	Ddr48p
NP_013899.1	Pai3p
NP_013900.1	Sip18p
NP_878143.1	Ymr175w-ap
NP_013901.1	Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks
NP_013902.1	Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p
NP_013903.1	Ymr178wp
NP_013904.1	Spt21p
NP_013905.1	RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm
NP_013906.1	Ymr181cp
NP_013907.1	Rgm1p
NP_878144.1	Ymr182w-ap
NP_013908.1	Sso2p
NP_013909.1	Protein of unknown function involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene
NP_013910.1	Ymr185wp
NP_013911.1	Hsc82p
NP_013912.1	Ymr187cp
NP_013913.1	Mrps17p
NP_013914.1	P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm
NP_013915.1	Sgs1p
NP_013916.2	Spg5p
NP_013917.1	Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p
NP_013918.1	Mrpl24p
NP_013920.1	Rpl36ap
NP_878145.1	Ymr194c-bp
NP_013922.1	Protein of unknown function, required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation
NP_013923.1	Ymr196wp
NP_013924.1	Vti1p
NP_013925.1	Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p
NP_013926.1	G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
NP_013927.1	Rot1p
NP_013928.1	Rad14p
NP_013929.1	Erg2p
NP_013930.1	Tom40p
NP_013931.1	Peripheral membrane protein of peroxisomes involved in peroxisomal inheritance
NP_013932.1	Pfk2p
NP_013933.1	Ymr206wp
NP_013934.1	Mitochondrial acetyl-coenzyme A carboxylase, catalyzes the production of malonyl-CoA in mitochondrial fatty acid biosynthesis
NP_013935.1	Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
NP_013936.1	Ymr209cp
NP_013937.1	Ymr210wp
NP_013938.1	Essential protein involved in mtDNA inheritance, may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family
NP_013939.1	Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies and is phosphorylated
NP_013940.1	Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p
NP_013941.2	Scj1p
NP_013942.1	Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
NP_013943.1	Sky1p
NP_013944.1	Gua1p
NP_013945.1	Trs130p
NP_013946.1	Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p
NP_013947.1	Phosphomevalonate kinase, an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
NP_013948.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_013949.1	Serine hydrolase that localizes to the cytoplasm; sequence is similar to Fsh1p and Fsh3p
NP_013950.1	Ubp8p
NP_013951.1	Subunit of a complex with Rad50p and Xrs2p (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for RMX function; widely conserved
NP_013952.1	Mrpl44p
NP_013953.1	Tma29p
NP_013954.1	Taf7p
NP_013955.1	Mtf1p
NP_013956.1	Rrp5p
NP_013957.1	Rps10bp
NP_878146.1	Ymr230w-ap
NP_013958.1	Pep5p
NP_013959.1	Fus2p
NP_013960.1	Tri1p
NP_013961.1	Rnh1p
NP_013962.1	Rna1p
NP_013963.1	Taf9p
NP_013964.1	Member of the ChAPs family (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins from the Golgi to the plasma membrane; may interact with ribosomes
NP_013965.1	Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p
NP_013966.1	Rnt1p
NP_013967.1	Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p
NP_013968.1	Yhm2p
NP_013969.3	Rpl20ap
NP_878147.1	Ymr242w-ap
NP_013970.1	Zrc1p
NP_013971.1	Ymr244wp
NP_013972.1	Ymr244c-ap
NP_013974.1	Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids
NP_013975.1	Rkr1p
NP_878148.1	Ymr247w-ap
NP_013976.1	Glutamate decarboxylase, converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress
NP_013977.1	Omega class glutathione transferase; putative cytosolic localization
NP_013978.1	Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor
NP_013979.1	Ymr252cp
NP_013980.1	Ymr253cp
NP_013982.1	Gfd1p
NP_013983.1	Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
NP_013984.1	Pet111p
NP_013985.1	Ymr258cp
NP_013986.1	Ymr259cp
NP_013987.1	Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3
NP_013988.1	Tps3p
NP_013989.1	Ymr262wp
NP_013990.1	Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance
NP_013991.1	Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination
NP_013992.1	Ymr265cp
NP_013993.1	Rsn1p
NP_013994.1	Ppa2p
NP_013995.1	Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling
NP_013996.2	Tma23p
NP_013997.1	Rrn9p
NP_013998.1	Ura10p
NP_013999.1	Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth
NP_878149.1	Ymr272w-bp
NP_014000.1	Zds1p
NP_014001.1	Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras and the a-factor mating pheromone
NP_014002.1	Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, disruption causes temperature-sensitive growth, overexpression causes missorting of amino acid permeases
NP_014003.1	Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle, involved in proteolysis, interacts with the proteasome
NP_014004.1	Fcp1p
NP_014005.1	Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential
NP_014006.1	Ymr279cp
NP_014007.1	Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements
NP_014008.1	Gpi12p
NP_014009.1	Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader
NP_014010.1	Rit1p
NP_014011.1	Yku70p
NP_014012.1	Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p
NP_014013.1	Mrpl33p
NP_014014.1	Dss1p
NP_014015.1	U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155
NP_014016.1	Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase), catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis
NP_014017.1	Has1p
NP_014019.1	Ymr291wp
NP_014020.1	Got1p
NP_014021.1	Putative protein similar to bacterial glutamyl-tRNA amidotransferases; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)
NP_014022.1	Jnm1p
NP_014024.1	Ymr295cp
NP_014025.1	Lcb1p
NP_014026.1	Vacuolar carboxypeptidase Y (proteinase C), broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family
NP_014027.1	Lip1p
NP_014028.1	Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration
NP_014029.1	Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway
NP_014030.1	Mitochondrial inner membrane ATP-binding cassette (ABC) transporter, exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol
NP_014031.1	Yme2p
NP_014032.1	Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1
NP_014033.1	Ubp15p
NP_014035.1	Scw10p
NP_014036.1	Protein involved in spore wall assembly, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_014038.1	Gas1p
NP_014039.1	Pse1p
NP_014040.1	Subunit of the eukaryotic translation initiation factor 3 (eIF3), involved in the assembly of preinitiation complex and start codon selection
NP_014041.1	Ymr310cp
NP_014042.1	Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2
NP_014043.1	Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity
NP_014044.1	Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes
NP_014045.1	Pre5p
NP_014046.1	Ymr315wp
NP_878150.1	Ymr315w-ap
NP_014047.1	Protein of unknown function, involved in invasive and pseudohyphal growth; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
NP_014050.1	Ymr317wp
NP_014051.1	NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance
NP_014052.1	Low-affinity Fe(II) transporter of the plasma membrane
NP_014054.1	Ymr321cp
NP_014055.1	Sno4p
NP_014056.1	Protein of unknown function, has similarity to enolases
NP_014060.1	Yrf1-6p
NP_014063.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_014065.1	Sno2p
NP_014066.1	Snz2p
NP_014067.1	Thi12p
NP_014068.1	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
NP_014069.1	Rpd3p
NP_014070.1	Pex6p
NP_014071.1	Mdj2p
NP_014072.1	Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
NP_014073.1	Pfa3p
NP_014074.1	Polyphosphatidylinositol phosphatase involved in the metabolism of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2); required for efficient mating; physically associates with and regulated by Vac14p; contains a SAC1-like domain
NP_014076.1	Membrane protein of the plasma membrane and ER, involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane
NP_014077.1	Kre1p
NP_014078.1	Vnx1p
NP_014079.1	Ynl320wp
NP_014081.1	Protein with similarity to hexose transporter family members, expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_014082.1	Pfs2p
NP_014083.2	Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway
NP_014084.1	Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase
NP_014085.1	Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain
NP_014086.1	Ynl313cp
NP_014087.1	Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
NP_014088.1	Skp2p
NP_014089.2	Zim17p
NP_014090.2	Stb1p
NP_014091.1	Kri1p
NP_014092.1	Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family
NP_014093.1	Mrps18p
NP_014094.1	Ynl305cp
NP_014095.2	Ypt11p
NP_014097.1	Rps19bp
NP_014098.1	Rpl18bp
NP_014099.1	Ynl300wp
NP_014100.2	Trf5p
NP_014101.1	Cla4p
NP_014102.1	Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p and localizes to the endosome; member of the Sec7p family of proteins
NP_014104.1	Ynl295wp
NP_014105.1	Rim21p
NP_014106.1	Msb3p
NP_014107.1	Pus4p
NP_014108.1	N-glycosylated integral membrane protein of the ER membrane and plasma membrane, functions as a stretch-activated Ca2+-permeable cation channel required for Ca2+ influx stimulated by pheromone; interacts with Cch1p; forms an oligomer
NP_014109.1	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
NP_014110.1	Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth
NP_014111.1	Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation, elongation and degradation; binds Cdc39p
NP_014112.1	Sec21p
NP_014113.1	Protein that binds to U2 snRNA and Prp11p, may be involved in U2 snRNA folding; contains two RNA recognition motifs (RRMs)
NP_058178.1	Ynl284c-bp
NP_058179.1	Ynl284c-ap
NP_014115.1	Mrpl10p
NP_014116.1	Wsc2p
NP_014117.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
NP_014118.1	Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus
NP_014119.1	Erg24p
NP_014120.1	Prm1p
NP_014121.1	Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation
NP_878151.1	Ynl277w-ap
NP_014122.1	Met2p
NP_014124.1	Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1
NP_014125.1	Gor1p
NP_014126.1	Tof1p
NP_014127.1	Sec2p
NP_014128.1	Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1
NP_014129.1	Arginine transporter; expression is normally very low and it is unclear what conditions would induce significant expression
NP_014130.1	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough is increased upon depletion of Sup35p
NP_014131.1	Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids
NP_014132.1	Pik1p
NP_014134.1	Putative translation initiation factor, as suggested by computational analysis of large-scale protein-protein interaction data
NP_014135.1	Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylcholine, found in the cytosol and microsomes, homologous to Pdr16p, deletion affects phospholipid composition
NP_014136.1	Yif1p
NP_014137.1	Pol2p
NP_014138.1	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
NP_014139.1	Ynl260cp
NP_014140.1	Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake
NP_014141.1	Peripheral membrane protein required for Golgi-to-ER retrograde traffic; component of the ER target site that interacts with coatomer, the major component of the COPI vesicle protein coat; also interacts with Cin5p and Sec39p
NP_014142.1	Sip3p
NP_014143.2	Multifunctional enzyme of the folic acid biosynthesis pathway, has dihydropteroate synthetase, dihydro-6-hydroxymethylpterin pyrophosphokinase, and dihydroneopterin aldolase activities
NP_014144.1	Protein with seven cysteine-rich CCHC zinc-finger motifs, similar to human CNBP, proposed to be involved in the RAS/cAMP signaling pathway
NP_014146.1	Tex1p
NP_014147.1	Mrpl17p
NP_014148.1	RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs
NP_014149.1	Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining
NP_014150.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_014151.1	Rpa49p
NP_014152.1	Ynl247wp
NP_014153.1	Vps75p
NP_014154.1	Cwc25p
NP_014155.1	Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase
NP_014156.1	Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo
NP_014157.1	Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy; interacts with Atg9p and is necessary for its trafficking
NP_014158.1	Zwf1p
NP_014159.1	Nuclear architecture related protein; component of the cytosolic iron-sulfur (FeS) protein assembly machinery, required for maturation of cytosolic and nuclear FeS proteins; homologous to human Narf
NP_014160.2	Lap3p
NP_014161.1	Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway
NP_014162.1	Ytp1p
NP_014163.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription
NP_014165.1	Ynl234wp
NP_014166.1	Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p
NP_014167.1	Subunit of the exosome, which is an essential complex present in both nucleus and cytoplasm that mediates RNA processing and degradation
NP_014168.1	Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p
NP_014169.1	Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex
NP_014170.1	Ure2p
NP_014172.1	Jjj1p
NP_014174.1	Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclear migration
NP_014175.1	Sqs1p
NP_014176.2	Cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation; mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p
NP_014177.1	Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo
NP_014178.1	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P
NP_014179.1	Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence
NP_014180.1	Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation
NP_014181.1	Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP)
NP_014183.1	Rap1p
NP_014184.1	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
NP_014185.1	Pex17p
NP_014186.1	Ynl213cp
NP_014187.1	Vid27p
NP_014188.1	Ynl211cp
NP_014189.1	Protein with RNA-binding motifs required for meiosis-specific mRNA splicing; required for chromosome pairing and meiotic recombination
NP_014190.1	Ssb2p
NP_014191.2	Ynl208wp
NP_014192.1	Rio2p
NP_014193.1	Rtt106p
NP_014195.1	Sps18p
NP_014197.2	Sps19p
NP_014198.1	Putative subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and the regulatory subunit Psy4p; required for cisplatin and oxaliplatin resistance; localizes to nucleus
NP_014199.1	Ynl200cp
NP_014200.1	Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p
NP_014202.1	Whi3p
NP_014203.1	Sporulation-specific protein with a leucine zipper motif
NP_014204.2	Ynl195cp
NP_014205.1	Ynl194cp
NP_014206.1	Ynl193wp
NP_014207.1	Chs1p
NP_014208.1	Probable glutamine amidotransferase, forms a complex with Dug1p and Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)
NP_014209.1	Ynl190wp
NP_014210.1	Srp1p
NP_014211.1	Kar1p
NP_014212.1	Ynl187wp
NP_014213.1	Ubp10p
NP_014214.1	Mrpl19p
NP_014216.1	Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation
NP_014217.1	Ipi3p
NP_014218.1	Ynl181wp
NP_014219.1	Rho5p
NP_014221.1	Rps3p
NP_014222.1	Mrpl22p
NP_014223.1	Ynl176cp
NP_014224.1	Protein of unknown function, localizes to the nucleolus and nucleoplasm; contains an RNA recognition motif (RRM) and has similarity to Nop12p, which is required for processing of pre-18S rRNA
NP_014226.1	Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations
NP_014227.1	Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_014230.1	Psd1p
NP_014231.1	Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_014232.1	Sko1p
NP_014233.1	Protein involved in organization of septins at the mother-bud neck, may interact directly with the Cdc11p septin, localizes to bud neck in a septin-dependent manner
NP_014234.1	Ynl165wp
NP_014235.1	Ibd2p
NP_014236.1	Ria1p
NP_076906.1	Ynl162w-ap
NP_014237.2	Rpl42ap
NP_014238.1	Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation
NP_014239.1	Ygp1p
NP_014240.1	Integral inner nuclear membrane protein that acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals
NP_014241.1	Pga1p
NP_014243.1	Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins
NP_014244.1	Ynl155wp
NP_014245.1	Yck2p
NP_014246.1	Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
NP_014247.1	Ynl152wp
NP_014248.1	Rpc31p
NP_014250.1	Pga2p
NP_014251.1	Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance
NP_014252.2	Lsm7p
NP_878152.1	Ynl146c-ap
NP_014253.1	Ynl146wp
NP_014254.1	Mfa2p
NP_014255.1	Ynl144cp
NP_014257.1	Mep2p
NP_014258.1	Adenine deaminase (adenine aminohydrolase), involved in purine salvage and nitrogen catabolism
NP_014260.1	Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids
NP_878153.1	Ysf3p
NP_014261.1	Srv2p
NP_014262.1	Nam9p
NP_014263.1	Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A
NP_014264.1	Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function
NP_014265.1	Ynl134cp
NP_014266.1	Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining
NP_014267.1	Kre33p
NP_014268.1	Tom22p
NP_014269.2	Cpt1p
NP_878154.1	Ynl130c-ap
NP_014270.1	Nrk1p
NP_014271.1	Tep1p
NP_014272.1	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far10p
NP_014273.1	Spc98p
NP_014274.1	Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane
NP_014275.1	Protein required for the assembly of box H/ACA snoRNPs and for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; has similarity to Gar1p and other RNA-binding proteins
NP_014276.1	Protein of unknown function which may contribute to lipid homeostasis and/or apoptosis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases
NP_014277.1	Ynl122cp
NP_014278.1	Tom70p
NP_014280.1	Protein with a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
NP_014281.1	Dcp2p
NP_014282.1	Mls1p
NP_014283.1	Protein involved in regulating spindle position and orientation, functionally redundant with Dma1p; homolog of S. pombe Dma1 and H. sapiens Chfr
NP_014284.1	Ynl115cp
NP_014286.1	Rpc19p
NP_014287.1	Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
NP_014288.1	Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; required for sterol C5-6 and fatty acid desaturation
NP_014289.1	Nop15p
NP_014291.1	Ynl108cp
NP_014292.1	Yaf9p
NP_014293.1	Polyphosphatidylinositol phosphatase, dephosphorylates a number of phosphatidylinositols (PIs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain
NP_014295.1	Leu4p
NP_014296.2	Met4p
NP_014297.1	Pol1p
NP_014298.1	Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
NP_014299.1	Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_014300.1	Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA
NP_014301.1	Ras2p
NP_878155.1	Ynl097c-bp
NP_014302.1	Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1)
NP_014303.1	Rps7bp
NP_014304.1	Ynl095cp
NP_014305.1	Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-protein interactions in large-scale studies suggests a possible role in actin filament organization
NP_014306.1	Ypt53p
NP_014307.1	Ynl092wp
NP_014308.1	Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the splicing factor Msl1p and also displays genetic interaction with MSL1
NP_014309.1	Rho2p
NP_014311.1	Top2p
NP_014312.1	Tcb2p
NP_014313.1	Ynl086wp
NP_014314.1	Protein that forms a complex with Pbp1p that may mediate posttranscriptional regulation of HO endonuclease; involved in propagation of M2 dsRNA satellite of L-A virus; contains a DTG signature typical of retroviral proteases
NP_014315.1	End3p
NP_014316.2	Sal1p
NP_014317.2	Pms1p
NP_014318.1	Sws2p
NP_014319.1	Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene
NP_014320.1	Tpm1p
NP_014321.1	Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network
NP_014322.1	Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_014323.1	Pleiotropic negative transcriptional regulator involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling
NP_014324.1	Imp4p
NP_014325.1	Serine-rich protein of unknown function; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide
NP_014326.1	Msk1p
NP_014327.1	Rnh201p
NP_014328.1	Lat1p
NP_014329.1	Tom7p
NP_014330.1	Rpl16bp
NP_014331.1	Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase
NP_878156.1	Ynl067w-bp
NP_014332.1	Rpl9bp
NP_014333.1	Sun4p
NP_014334.1	Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
NP_014335.1	Ydj1p
NP_014336.1	S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene
NP_014337.1	Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
NP_014338.1	Probable RNA m(5)C methyltransferase, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles
NP_014339.1	Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
NP_014340.1	Ynl058cp
NP_014342.1	Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene
NP_014343.1	Por1p
NP_058180.1	Ynl054w-ap
NP_014344.1	Vac7p
NP_014345.1	Msg5p
NP_014346.1	Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth
NP_014347.1	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_014348.1	Ynl050cp
NP_014349.1	Sfb2p
NP_014350.1	Alpha-1,2-mannosyltransferase, catalyzes sequential addition of the two terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER
NP_014351.1	Slm2p
NP_014352.1	Ynl046wp
NP_014353.1	Ynl045wp
NP_014354.2	Yip3p
NP_878157.1	Ynl042w-bp
NP_014356.1	Protein of unknown function, potential Cdc28p substrate; overproduction suppresses a pam1 slv3 double null mutation and confers resistance to methylmercury
NP_014357.1	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_014358.1	Ynl040wp
NP_014359.1	Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs
NP_014360.2	Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-H protein
NP_014361.1	Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
NP_014362.1	Nce103p
NP_014363.1	Ynl035cp
NP_014364.1	Ynl034wp
NP_014365.1	Ynl033wp
NP_014366.1	Tyrosine phosphatase that plays a role in actin filament organization and endocytosis; localized to the cytoplasm
NP_014367.1	One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation
NP_014368.1	One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
NP_014369.1	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
NP_014371.1	Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation
NP_014372.1	Sam50p
NP_014373.1	Ssn8p
NP_878158.1	Ynl024c-ap
NP_014374.1	Ynl024cp
NP_014375.1	Protein that binds to Fpr1p (FKBP12), conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; has similarity to putative transcription factors, including D. melanogaster shuttle craft and human NFX1
NP_014376.1	Ynl022cp
NP_014377.1	Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation
NP_014378.1	Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis
NP_014379.1	Ynl019cp
NP_014380.1	Ynl018cp
NP_014382.1	Pub1p
NP_014383.1	Pbi2p
NP_014384.1	Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells
NP_014386.2	Spo1p
NP_014387.1	Ynl011cp
NP_014388.1	Ynl010wp
NP_014389.1	Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids
NP_014390.1	Putative integral membrane E3 ubiquitin ligase; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals
NP_014391.1	Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins
NP_014392.1	Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat
NP_014393.1	Mrp7p
NP_014394.2	Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p
NP_014395.1	S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth
NP_014396.1	Rlp7p
NP_014397.1	Endoribonuclease; functions in no-go mRNA decay, protein translation to promote G1 progression and differentiation, required for meiotic cell division; similar to the eukaryotic Pelota
NP_014398.1	Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein
NP_014399.1	Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p
NP_014400.1	Rpc34p
NP_014401.1	Ynr004wp
NP_014403.1	Vps27p
NP_014404.1	E2-like enzyme involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy and Cvt
NP_014405.1	Lro1p
NP_014406.1	Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase
NP_014407.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; component of the Med9/10 module; required for regulation of RNA polymerase II activity
NP_014408.1	RNA-dependent ATPase in the DEAH-box family, required for activation of the spliceosome before the first transesterification step in RNA splicing
NP_014409.1	Urk1p
NP_014410.1	Pho91p
NP_014411.1	Ynr014wp
NP_014412.1	Smm1p
NP_014413.1	Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
NP_014414.1	Tim23p
NP_014415.1	Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
NP_014416.1	Are2p
NP_014417.1	Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex
NP_014418.1	Ynr021wp
NP_014419.1	Mrpl50p
NP_014420.1	Snf12p
NP_014421.1	Ynr024wp
NP_014423.1	Sec12p
NP_014424.1	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
NP_014425.1	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; similarity to Cpr4p suggests a potential role in the secretory pathway
NP_014426.1	Ynr029cp
NP_014427.1	Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation
NP_014428.1	Ssk2p
NP_014429.1	Putative serine/threonine protein phosphatase, required for glycogen accumulation; interacts with Tap42p, which binds to and regulates other protein phosphatases
NP_014430.1	Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear
NP_014431.1	Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB
NP_014432.1	Sol1p
NP_061494.1	Ynr034w-ap
NP_014433.1	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin
NP_014434.1	Ynr036cp
NP_014435.1	Rsm19p
NP_014436.1	Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family
NP_014437.1	Zrg17p
NP_014438.1	Ynr040wp
NP_014439.1	Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis
NP_014441.1	Mvd1p
NP_014442.1	Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds
NP_014443.1	Pet494p
NP_014444.1	Trm112p
NP_014445.1	Ynr047wp
NP_014446.1	Ynr048wp
NP_014447.1	Probable component of the secretory vesicle docking complex, acts at a late step in secretion; shows genetic and physical interactions with Sec1p and is enriched in microsomal membrane fractions; required for sporulation
NP_014448.1	Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, which is the seventh step in lysine biosynthesis pathway
NP_014449.1	Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A
NP_014450.1	RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation
NP_014451.1	Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation
NP_014452.1	Essential nucleolar protein involved in pre-18S rRNA processing; component of the small subunit (SSU) processome; has sequence similarity to mABT1, a mouse transcription activator
NP_014453.1	Putative transporter in the major facilitator superfamily (DHA1 family) of multidrug resistance transporters; mutations in membrane-spanning domains permit cation and histidinol uptake
NP_014454.1	Putative transmembrane protein involved in the biotin biosynthesis pathway; responsible for uptake of 7-keto 8-aminopelargonic acid; BIO5 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis
NP_014455.1	Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels
NP_014456.1	Bio3p
NP_014457.1	Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation
NP_014458.1	Fre4p
NP_014459.1	Ynr061cp
NP_014460.1	Ynr062cp
NP_014461.1	Ynr063wp
NP_014462.1	Ynr064cp
NP_014463.1	Ynr065cp
NP_014464.1	Ynr066cp
NP_014465.1	Dse4p
NP_014466.1	Ynr068cp
NP_014467.1	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
NP_014468.1	Ynr070wp
NP_014469.1	Ynr071cp
NP_014470.1	Hxt17p
NP_014471.1	Ynr073cp
NP_014472.1	Mitochondrial cell death effector that translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase
NP_014473.1	Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
NP_878159.1	Ynr075c-ap
NP_014474.1	Pau6p
NP_878160.1	Yol166w-ap
NP_014477.1	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
NP_878161.1	Yol164w-ap
NP_014478.1	Bds1p
NP_014479.1	Yol163wp
NP_014480.1	Yol162wp
NP_076909.1	Yol159c-ap
NP_014483.1	Yol159cp
NP_014484.1	Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment
NP_014485.1	Yol157cp
NP_014486.1	Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance
NP_878162.1	Yol155w-ap
NP_014487.1	Hpf1p
NP_014488.1	Zps1p
NP_014489.2	Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels
NP_014490.1	NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
NP_014492.1	Subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; enhances the activity of catalytic subunit Dcp2p; regulated by DEAD box protein Dhh1p
NP_014493.1	Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex
NP_014494.1	Pex11p
NP_014495.2	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
NP_014496.1	Ctr9p
NP_014497.1	Nucleolar protein required for 60S ribosomal subunit biogenesis
NP_014498.1	Rib4p
NP_014499.1	Rrp40p
NP_014500.1	Putative carboxymethyltransferase, similar to Ppm1p but biochemical activity not yet demonstrated; required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA
NP_014501.1	Arg8p
NP_014502.1	Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with the translation initiation factor eIF4G (Tif4631p or Tif4632p)
NP_014503.1	Yol138cp
NP_014504.1	Protein of unknown function containing 8 putative transmembrane seqments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
NP_014505.1	Pfk27p
NP_014506.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_014508.1	RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF
NP_014509.1	Gas4p
NP_014510.1	Yol131wp
NP_014511.1	Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions
NP_014512.1	Vps68p
NP_014513.1	Ygk3p
NP_014514.1	Rpl25p
NP_014515.2	Mdh2p
NP_014516.1	Trm13p
NP_014517.1	Trm11p
NP_014518.1	Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
NP_014519.1	Smf1p
NP_014520.1	Rps19ap
NP_014521.1	Rpl18ap
NP_014522.1	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
NP_014524.1	Subunit of the COP9 signalosome (CSN) complex that cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response
NP_014525.1	Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus
NP_014526.1	Pap2p
NP_014527.1	Yol114cp
NP_014528.1	Skm1p
NP_014529.1	Msb4p
NP_014530.1	Protein required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes and interacts with YOR164C; contains a ubiquitin-like (UBL) domain
NP_014531.1	Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization
NP_014532.1	Zeo1p
NP_014533.1	Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain
NP_014534.1	Yol107wp
NP_014536.1	Wsc3p
NP_014537.1	Ndj1p
NP_058181.1	Yol103w-bp
NP_058182.1	Yol103w-ap
NP_014538.2	Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively
NP_014539.1	tRNA 2'-phosphotransferase, catalyzes the final step in yeast tRNA splicing: the transfer of the 2'-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1''-2''cyclic phosphate and nicotinamide
NP_014540.1	Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
NP_014541.1	Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p
NP_014543.1	Yol098cp
NP_878163.1	Yol097w-ap
NP_014544.1	Wrs1p
NP_014545.2	O-methyltransferase, catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex
NP_014546.1	Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription; has homology to E. coli helicase uvrD
NP_014547.1	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
NP_014548.1	tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs
NP_014549.1	Yol092wp
NP_014550.1	Spo21p
NP_014551.1	Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP
NP_014552.1	Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression
NP_014553.1	Mpd2p
NP_014554.1	Yol087cp
NP_076910.1	Yol086w-ap
NP_014555.1	Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
NP_014557.1	Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
NP_014559.1	Protein involved in the cytoplasm-to-vacuole targeting pathway and in autophagy, recognizes cargo proteins and delivers them to the preautophagosomal structure for eventual engulfment by the autophagosome and degradation
NP_014560.1	Ira2p
NP_014561.1	Rex4p
NP_014563.1	Component of a membrane-bound complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth
NP_014564.1	Subunit k of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase
NP_014565.1	Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif
NP_014566.1	Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes N-acetylation of proteins with specific N-terminal sequences; involved in mitochondrial inheritance and actin assembly
NP_014567.1	Yol075cp
NP_014568.1	Yol073cp
NP_014569.1	Thp1p
NP_014570.1	Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation
NP_014571.1	Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, and bud neck; potential Cdc28p substrate
NP_014572.1	Nuf2p
NP_014573.1	NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance
NP_014574.1	Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus
NP_014575.1	Rib2p
NP_014576.1	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins
NP_014577.1	Met22p
NP_014578.1	Protein involved in transcriptional regulation of RNR2 and RNR3; expression of the gene is induced by DNA damage and null mutations confer increased resistance to hydroxyurea; N-terminal region has a leucine repeat and a WD40 repeat
NP_014579.1	Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport
NP_014580.1	Prs5p
NP_014581.1	Protein required for normal mitochondrial morphology, has similarity to hemolysins
NP_014582.1	NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria
NP_014583.1	Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate
NP_014584.1	Yol057wp
NP_014585.1	Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event
NP_014586.1	Thi20p
NP_014587.1	Psh1p
NP_014588.1	Putative protein of unknown function; YOL053W is not an essential gene; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)
NP_014589.1	Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses
NP_014590.1	Spe2p
NP_014591.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors
NP_014593.1	Gsh2p
NP_014594.2	Yol048cp
NP_014595.2	Yol047cp
NP_014597.1	Psk2p
NP_014598.1	Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly
NP_014599.1	Ntg2p
NP_014600.1	Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_014601.1	Nucleolar protein, required for pre-25S rRNA processing; contains an RNA recognition motif (RRM) and has similarity to Nop13p, Nsr1p, and putative orthologs in Drosophila and S. pombe
NP_014602.1	Rps15p
NP_014603.1	Rpp2ap
NP_878164.1	Yol038c-ap
NP_014604.1	Pre6p
NP_014606.1	Yol036wp
NP_014608.1	Structural maintenance of chromosomes (SMC) protein; essential subunit of the Mms21-Smc5-Smc6 complex; required for growth and DNA repair; S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair
NP_014609.1	Mse1p
NP_014610.1	Protein with a possible role in phospholipid biosynthesis, based on inositol-excreting phenotype of the null mutant and its suppression by exogenous choline
NP_014611.1	Sil1p
NP_014612.1	Gas5p
NP_014613.1	Yol029cp
NP_014614.1	Yap7p
NP_014615.1	Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome
NP_014616.1	Mitochondrial outer membrane protein, required for assembly of the translocase of the outer membrane (TOM) complex and thereby for mitochondrial protein import; N terminus is exposed to the cytosol: transmembrane segment is highly conserved
NP_014617.1	Protein involved in determination of longevity; LAG2 gene is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells
NP_014618.1	Yol024wp
NP_014619.1	Mitochondrial translation initiation factor 2
NP_014620.1	Tsr4p
NP_014621.1	Dis3p
NP_014622.1	Tat2p
NP_878165.1	Yol019w-ap
NP_014623.1	Yol019wp
NP_014624.1	Tlg2p
NP_014625.1	Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex
NP_014626.1	Cmk2p
NP_014627.1	hypothetical protein; null mutant displays increased levels of spontaneous Rad52 foci
NP_014628.1	Yol014wp
NP_878166.1	Yol013w-ap
NP_014630.1	Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger
NP_014631.1	Htz1p
NP_014632.1	Plb3p
NP_014633.1	Rcl1p
NP_014634.1	Mitochondrial outer membrane protein, required for transmission of mitochondria to daughter cells; component of the Mdm10-Mdm12-Mmm1 complex involved in import and assembly of outer membrane beta-barrel proteins
NP_014635.1	Coq10p
NP_014636.1	Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene
NP_014637.1	Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination
NP_014638.1	Rpb11p
NP_014639.1	Sin3p
NP_014640.1	Pfa4p
NP_014641.2	Plasma membrane protein involved in zinc metabolism and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc
NP_014642.1	Pho80p
NP_014643.1	Rrp6p
NP_014644.1	Alpha 1,3 glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease
NP_014645.1	Ysp3p
NP_014646.1	Utp23p
NP_014647.1	Dnl4p
NP_014648.1	Tsr3p
NP_014649.1	Sgt2p
NP_014650.1	Slg1p
NP_014651.1	Yor008c-ap
NP_014652.1	Tir4p
NP_014653.1	Tir2p
NP_014654.1	Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth
NP_878167.1	Yor011w-ap
NP_014655.1	Yor012wp
NP_014657.1	Rts1p
NP_014659.1	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport
NP_014660.1	Protein with a role in mitochondrial RNA stability and/or processing, located in the mitochondrial membrane
NP_014661.1	Rod1p
NP_014662.1	Yor019wp
NP_014663.1	Mitochondrial matrix co-chaperonin that inhibits the ATPase activity of Hsp60p, a mitochondrial chaperonin; involved in protein folding and sorting in the mitochondria; 10 kD heat shock protein with similarity to E. coli groES
NP_878168.1	Yor020w-ap
NP_014664.1	Yor021cp
NP_014665.1	Yor022cp
NP_014666.1	Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex
NP_014668.1	Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
NP_014669.1	Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p
NP_014670.1	Sti1p
NP_014671.1	Cin5p
NP_014673.1	Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p
NP_014674.1	Crs5p
NP_014675.1	Hms1p
NP_878169.1	Yor032w-ap
NP_014676.1	Exo1p
NP_014677.1	Ankyrin repeat-containing protein similar to Akr1p; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p
NP_878170.1	Yor034c-ap
NP_014678.1	She4p
NP_014679.1	Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin
NP_014680.2	Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)
NP_014681.1	Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p
NP_014682.1	Ckb2p
NP_014683.1	Mitochondrial glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate
NP_014685.1	Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
NP_014686.1	Whi2p
NP_014687.1	Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; null mutant displays increased levels of spontaneous Rad52 foci
NP_014688.1	Tom6p
NP_014689.1	Dbp5p
NP_014690.1	Std1p
NP_014691.1	Rat1p
NP_014692.1	Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane
NP_014694.1	Yor051cp
NP_014695.1	Yor052cp
NP_014697.1	Vhs3p
NP_014699.1	Nob1p
NP_014700.1	Sgt1p
NP_116582.1	Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate
NP_014703.1	Yor060cp
NP_014704.1	Cka2p
NP_014705.1	Yor062cp
NP_014706.1	Rpl3p
NP_014707.1	Yng1p
NP_014708.1	Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex
NP_014709.1	Msa1p
NP_014710.1	Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p
NP_014712.2	Vps5p
NP_014711.1	Vam10p
NP_014713.1	Gyp1p
NP_014714.1	Transporter of thiamine or related compound; shares sequence similarity to Thi7p; proposed to be involved in 5-fluorocytosine sensitivity
NP_878171.1	Yor072w-bp
NP_014716.1	Sgo1p
NP_014717.2	Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S
NP_014718.1	t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R/v-SNAREs on Golgi-derived vesicles at the ER; part of Dsl1p complex
NP_014719.1	Ski7p
NP_014720.1	Rts2p
NP_014721.1	Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern
NP_014722.1	Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation
NP_014723.1	Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication, involved in invasive and pseudohyphal growth
NP_014724.1	Triacylglycerol lipase involved in TAG mobilization; localizes to lipid particles; potential Cdc28p substrate
NP_014726.1	Whi5p
NP_014727.1	Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction
NP_014728.1	Ost3p
NP_014729.1	Tcb1p
NP_014730.2	Yvc1p
NP_014732.1	Vps21p
NP_014733.1	Ptc5p
NP_014734.2	Tma46p
NP_014735.1	Non-essential protein of unknown function
NP_014736.1	Yor093cp
NP_014737.1	Glucose-repressible ADP-ribosylation factor, GTPase of the Ras superfamily involved in development of polarity
NP_014738.1	Rki1p
NP_014739.1	Rps7ap
NP_014740.1	Yor097cp
NP_014741.1	Nup1p
NP_014742.1	Ktr1p
NP_014743.1	Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation
NP_014744.1	Ras1p
NP_014746.2	Ost2p
NP_014747.1	Protein that induces appearance of [PIN+] prion when overproduced
NP_014749.1	Vam3p
NP_014750.1	Rgs2p
NP_014751.1	Leu9p
NP_014752.1	Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains
NP_014753.1	Tfc7p
NP_014754.1	Yor111wp
NP_014755.1	Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p
NP_014756.1	Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance
NP_014758.1	Trs33p
NP_014759.1	Rpo31p
NP_014760.1	Rpt5p
NP_014761.1	Yor118wp
NP_014762.1	Rio1p
NP_014763.1	Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family
NP_014765.1	Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, involved in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol
NP_014766.1	Leo1p
NP_014767.1	Ubp2p
NP_014768.2	Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation
NP_014769.1	Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing
NP_014770.1	Rga1p
NP_014771.1	Phosphoribosylaminoimidazole carboxylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine
NP_014772.1	Yor129cp
NP_014773.1	Ort1p
NP_014774.1	Yor131cp
NP_014775.1	Vps17p
NP_014776.1	Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
NP_014777.1	Rho GTPase activating protein (RhoGAP), stimulates the intrinsic GTPase activity of Rho1p, which plays a role in actin cytoskeleton organization and control of cell wall synthesis; structurally and functionally related to Sac7p
NP_014779.1	Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated
NP_014780.1	Sia1p
NP_014781.1	Rup1p
NP_014783.1	Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p
NP_014784.1	Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
NP_014785.1	Lsc1p
NP_058183.1	Yor142w-bp
NP_058184.1	Yor142w-ap
NP_014786.1	Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate)
NP_014787.1	Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity; involved in homologous recombination-mediated DNA repair
NP_014788.1	Pno1p
NP_014790.2	Mitochondrial inner membrane protein with similarity to Mdm31p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34
NP_014791.1	Spp2p
NP_014792.1	Smp3p
NP_014793.1	Mrpl23p
NP_014794.1	Rpb2p
NP_014795.1	Yor152cp
NP_014796.1	Plasma membrane ATP-binding cassette (ABC) transporter, short-lived multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth
NP_014797.1	Slp1p
NP_014798.1	Isn1p
NP_014799.1	SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; involved in maintenance of proper telomere length
NP_014800.1	Pup1p
NP_014801.1	Pet123p
NP_014802.1	Sme1p
NP_014803.1	Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus export; promotes dissociation of mRNAs from the nucleus-cytoplasm mRNA shuttling protein Npl3p
NP_014804.1	Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport
NP_878172.1	Yor161c-cp
NP_014805.1	Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes
NP_014806.1	Diadenosine polyphosphate hydrolase, member of the MutT family of nucleotide hydrolases with high specificity for diadenosine hexa- and pentaphosphates, required for efficient hydrolysis of diphosphorylated inositol polyphosphates
NP_014807.1	Yor164cp
NP_014808.1	Sey1p
NP_014809.1	Swt1p
NP_014810.1	Rps28ap
NP_014811.1	Glutamine tRNA synthetase, monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Glu); N-terminal domain proposed to be involved in enzyme-tRNA interactions
NP_014814.1	Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes
NP_014815.1	Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes
NP_014816.2	Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, similar to Dcs1p.
NP_014817.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_014818.1	Lysophospholipid acyltransferase, partially redundant with Slc1p; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids
NP_014819.1	Hem15p
NP_014820.1	Mpc54p
NP_014821.1	Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock
NP_014822.1	Syc1p
NP_014823.1	Peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, involved in fatty acid metabolism, contains peroxisome targeting signals at amino and carboxy termini
NP_014824.1	Las17p
NP_014825.1	Rps30bp
NP_014826.1	Protein of unknown function, required for survival upon exposure to K1 killer toxin
NP_014827.1	Ser1p
NP_014828.1	Gsp2p
NP_014829.1	Yor186wp
NP_014830.1	Tuf1p
NP_014831.1	Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway, potential Cdc28p substrate; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4
NP_014832.1	Ies4p
NP_014833.1	Spr1p
NP_014834.1	Ris1p
NP_014835.1	Transporter of thiamine or related compound; shares sequence similarity with Thi7p
NP_878173.1	Yor192c-cp
NP_058185.1	Yor192c-bp
NP_058186.1	Yor192c-ap
NP_014836.1	Pex27p
NP_014837.1	Toa1p
NP_014838.1	Slk19p
NP_014839.1	Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to E. coli lipoic acid synthase
NP_014840.2	Putative cysteine protease similar to mammalian caspases, involved in regulation of apoptosis upon hydrogen peroxide treatment
NP_014841.1	Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity
NP_014844.1	Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA
NP_014845.1	Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p
NP_014847.1	Ded1p
NP_014848.1	Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media
NP_014849.1	Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors
NP_014850.1	Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs
NP_014851.1	Ptp2p
NP_014852.1	Npt1p
NP_014853.1	Rpb10p
NP_014854.2	Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy
NP_014855.1	Ste4p
NP_014856.1	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; stimulates Sas2p HAT activity
NP_014857.1	Yor214cp
NP_014858.1	Putative protein of unknown function; the authentic protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays altered rate of mitochondrial loss and reduced growth rate in minimal glycerol media
NP_014859.1	Rud3p
NP_014860.1	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
NP_014862.1	Ste13p
NP_014863.1	Rcn2p
NP_014864.2	Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling
NP_014865.1	Odc2p
NP_014866.1	Yor223wp
NP_014867.1	Rpb8p
NP_014869.1	Isu2p
NP_014870.1	Yor227wp
NP_014871.1	Yor228cp
NP_014872.1	Wtm2p
NP_014873.1	Wtm1p
NP_014874.1	Mkk1p
NP_014875.1	Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE
NP_014876.1	Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck
NP_014877.1	Rpl33bp
NP_014879.1	Dihydrofolate reductase, part of the dTTP biosynthetic pathway, involved in folate metabolism, possibly required for mitochondrial function
NP_014880.1	Protein implicated in the regulation of ergosterol biosynthesis; one of a seven member gene family with a common essential function and non-essential unique functions; similar to human oxysterol binding protein (OSBP)
NP_014881.2	Yor238wp
NP_014882.2	Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases
NP_014884.1	Met7p
NP_014885.1	Ssp2p
NP_014886.1	Pus7p
NP_014887.1	Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression
NP_014888.1	Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles
NP_014889.1	Yor246cp
NP_014890.1	Srl1p
NP_014892.1	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
NP_014893.1	Subunit of cleavage factor I (CFI), involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation
NP_014894.1	Yor251cp
NP_014895.2	Tma16p
NP_014896.1	Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
NP_014897.1	Sec63p
NP_014898.1	Protein involved in sporulation; required for the construction of the outer spore wall layers; required for proper localization of Spo14p
NP_014899.1	Tre2p
NP_014900.1	Cdc31p
NP_014901.1	Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia
NP_014902.1	Rpt4p
NP_014903.1	Gcd1p
NP_014904.1	Rpn8p
NP_014905.1	Yor262wp
NP_014907.1	Dse3p
NP_014908.1	Rbl2p
NP_014909.1	Pnt1p
NP_014910.1	Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis
NP_014911.1	Yor268cp
NP_014912.1	Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1
NP_014913.1	Vph1p
NP_014914.1	Putative protein, predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis
NP_014915.1	Ytm1p
NP_014916.1	Tpo4p
NP_014917.1	Mod5p
NP_014918.1	Rim20p
NP_014919.1	Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E
NP_014921.1	Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in the heme biosynthetic pathway
NP_014922.1	Rfm1p
NP_014923.1	Serine hydrolase; sequence is similar to Fsh1p and Fsh2p
NP_014924.1	Plp2p
NP_014926.1	Yor283wp
NP_014927.1	Hua2p
NP_014928.1	Yor285wp
NP_014929.1	Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media
NP_014930.1	Yor287cp
NP_014931.1	Mpd1p
NP_014932.1	Yor289wp
NP_014933.1	Snf2p
NP_014934.1	Yor291wp
NP_014935.1	Yor292cp
NP_014936.1	Rps10ap
NP_878174.1	Yor293c-ap
NP_014937.1	Rrs1p
NP_014938.1	Uaf30p
NP_014939.1	Yor296wp
NP_014940.1	Tim18p
NP_014941.1	Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acyltransferases
NP_014942.2	Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations
NP_014943.1	Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane
NP_014945.1	Rax1p
NP_014946.1	Yor302wp
NP_014947.1	Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader
NP_014948.1	Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth
NP_014949.1	Yor304c-ap
NP_014950.1	Yor305wp
NP_014951.1	Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport
NP_014952.1	Sly41p
NP_014953.1	Snu66p
NP_014955.1	Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA
NP_014956.1	Hsd1p
NP_014957.2	Rpl20bp
NP_014958.1	Sps4p
NP_014960.1	Sfg1p
NP_014961.1	Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium
NP_878175.1	Yor316c-ap
NP_014962.1	Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase
NP_014964.1	U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)
NP_014965.1	N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
NP_014966.1	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; target for new antifungals
NP_014967.1	Protein of unknown function involved in maintenance of proper telomere length; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface
NP_014968.1	Pro2p
NP_014969.1	Tail-anchored endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress
NP_014971.1	One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle
NP_014972.1	Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins
NP_014973.1	Pdr10p
NP_014974.1	Scd5p
NP_014975.2	Mip1p
NP_014977.1	Vma4p
NP_014979.1	Mrs2p
NP_014980.1	Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog
NP_014981.1	Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects
NP_014982.1	Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein
NP_014983.1	Yor338wp
NP_014984.1	Ubiquitin-conjugating enzyme most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2
NP_014985.1	Rpa43p
NP_014986.1	Rpa190p
NP_014987.1	Yor342cp
NP_620389.1	Yor343w-bp
NP_620390.1	Yor343w-ap
NP_014989.1	Tye7p
NP_014991.1	Rev1p
NP_014992.1	Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux
NP_014993.1	Put4p
NP_014994.1	Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
NP_014995.1	Mne1p
NP_014996.1	Mek1p
NP_014997.1	Yor352wp
NP_014998.1	Sog2p
NP_014999.1	Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_015000.1	Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_015001.1	Yor356wp
NP_015002.1	Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p
NP_015003.1	Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex
NP_015004.1	Vts1p
NP_015005.1	Pde2p
NP_015006.1	Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes
NP_015007.1	Pre10p
NP_015008.1	Pip2p
NP_015010.1	Yor365cp
NP_015012.1	Scp1p
NP_015013.1	Rad17p
NP_015014.1	Rps12p
NP_015015.1	Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
NP_015016.1	Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb2p
NP_015017.1	Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes
NP_015018.1	Nud1p
NP_015019.1	Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed
NP_015020.1	NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
NP_878176.1	Yor376w-ap
NP_015022.1	Atf1p
NP_015023.1	Yor378wp
NP_015025.1	Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins
NP_015026.1	Fre3p
NP_878177.1	Yor381w-ap
NP_015027.1	Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
NP_015028.1	Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
NP_015029.1	Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_015030.1	Yor385wp
NP_015031.1	Phr1p
NP_015032.1	Yor387cp
NP_015033.1	NAD(+)-dependent formate dehydrogenase, may protect cells from exogenous formate
NP_015034.1	Yor389wp
NP_015035.1	Yor390wp
NP_015036.1	Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease
NP_015038.1	Protein of unknown function, has similarity to enolases
NP_878178.1	Yor394c-ap
NP_061495.2	Yrf1-8p
NP_015040.1	Yrf1-7p
NP_015042.1	Protein of unknown function, has similarity to enolases
NP_015043.1	Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease
NP_015044.1	Ypl279cp
NP_015045.1	Ypl278cp
NP_015046.1	Ypl277cp
NP_015049.1	Sam3p
NP_015050.1	Sam4p
NP_015051.1	Ypl272cp
NP_015052.1	Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
NP_015053.2	Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter
NP_015054.1	Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase
NP_015055.1	Plc1p
NP_015056.1	Cell cycle regulated protein of unknown function; associated with Cdh1p and may supress the APC/C[Cdh1]-mediated proteolysis of mitotic cyclins
NP_015057.1	Essential 18S rRNA dimethylase (dimethyladenosine transferase), responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing
NP_015058.1	Dip5p
NP_015059.1	Ypl264cp
NP_015060.1	Kel3p
NP_015061.1	Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria
NP_015063.1	Ypl260wp
NP_015064.1	Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting
NP_015065.1	Thi21p
NP_058189.1	Ypl257w-bp
NP_058190.1	Ypl257w-ap
NP_015066.1	Ypl257wp
NP_015067.1	G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
NP_015068.1	Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p
NP_015069.1	Hfi1p
NP_015070.1	Vik1p
NP_015071.1	Yah1p
NP_015073.1	Protein of unknown function; mobilized into polysomes upon a shift from a fermentable to nonfermentable carbon source; potential Cdc28p substrate
NP_015074.1	Rpl36bp
NP_015075.1	Gyp5p
NP_015076.1	Gal4p
NP_015077.1	Ypl247cp
NP_015078.1	Rbd2p
NP_015079.1	Ypl245wp
NP_015080.1	Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1
NP_015081.1	Srp68p
NP_015082.1	Iqg1p
NP_015083.1	Tubulin folding factor C (putative) involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
NP_015084.1	Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p
NP_015085.1	Yar1p
NP_015087.1	Sui3p
NP_015088.1	Ypl236cp
NP_015089.1	Rvb2p
NP_015090.1	Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen
NP_015091.1	Nsl1p
NP_015092.1	Sso1p
NP_015093.1	Fas2p
NP_015094.1	Usv1p
NP_015095.1	Ypl229wp
NP_015096.1	Cet1p
NP_015097.1	UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum
NP_015098.1	New1p
NP_015099.1	Ypl225wp
NP_015100.1	Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p
NP_015101.1	Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
NP_015102.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_015103.1	Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance
NP_015104.1	Rpl1ap
NP_015105.1	Pcl8p
NP_015106.1	Sar1p
NP_015107.1	Essential conserved nucleolar GTP-binding protein required for synthesis of 40S ribosomal subunits and for processing of the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, has similarity to Tsr1p
NP_015108.1	Ypl216wp
NP_015109.1	Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp4p and function is partially redundant with that of Cbp4p
NP_015110.1	Thi6p
NP_015111.1	Lea1p
NP_015112.1	tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA
NP_015113.1	Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p
NP_015114.2	Srp72p
NP_015115.1	Ipl1p
NP_015116.1	SET-domain lysine-N-methyltransferase, catalyzes the formation of dimethyllysine residues on the large ribsomal subunit protein L23a (RPL23A and RPL23B)
NP_015117.1	Tyw1p
NP_015118.1	Ypl206cp
NP_015120.1	Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta)
NP_015121.1	cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk3p
NP_015122.1	Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; similar to Aft1p
NP_015123.1	Yig1p
NP_015124.1	Protein required for accurate chromosome segregation during meiosis
NP_015126.1	Rpl7bp
NP_015128.1	Protein of unknown function required for normal levels of resistance to oxidative damage, null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes but not in prokaryotes
NP_015129.1	Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function
NP_015130.1	Ddc1p
NP_015131.1	Rsa1p
NP_015132.1	Prm3p
NP_015133.1	Ypl191cp
NP_015134.1	Single stranded RNA binding protein; acidic ribonucleoprotein; required for termination of non-poly(A) transcripts and efficient splicing; interacts with Nrd1p
NP_878179.1	Putative cytochrome oxidase assembly factor; identified by homology to Ashbya gossypii; null mutation results in respiratory deficiency with specific loss of cytochrome oxidase activity
NP_015135.1	Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog
NP_015136.1	Pos5p
NP_015137.1	Mf(alpha)1p
NP_015138.1	Uip4p
NP_015140.1	Putative RNA binding protein
NP_015141.1	Ypl183w-ap
NP_015142.1	Rtt10p
NP_015144.1	Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain
NP_015145.1	Tco89p
NP_015146.1	Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational suppressors
NP_015147.1	Small subunit of the heterodimeric cap binding complex that also contains Sto1p, component of the spliceosomal commitment complex; interacts with Npl3p, possibly to package mRNA for export from the nucleus; contains an RNA-binding motif
NP_015148.1	Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription
NP_015149.1	Tre1p
NP_015150.2	UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins
NP_015151.1	Nip100p
NP_015152.1	Mrpl40p
NP_015153.1	Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders
NP_015154.1	Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism
NP_015155.1	Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
NP_015156.1	Poly(A)RNA binding protein involved in nuclear mRNA export, component of the nuclear pore; ortholog of human TAP
NP_015157.1	Ypl168wp
NP_015158.1	Rev3p
NP_015159.1	Protein specifically required for autophagy; may function in autophagosome formation at the pre-autophagosomal structure in collaboration with other autophagy proteins
NP_015160.1	Set6p
NP_015161.1	Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability
NP_015162.1	Svs1p
NP_015163.1	Ypl162cp
NP_015164.1	Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length
NP_015165.1	Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA
NP_015166.1	Pet20p
NP_015167.1	Protein of unknown function; null mutant displays increased frequency of mitochondrial genome loss (petite formation) and reduced growth rate in minimal glycerol media
NP_015168.1	Trimethyl guanosine synthase, conserved nucleolar methyl transferase responsible for conversion of the m(7)G cap structure of snRNAs and snoRNAs to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology
NP_015169.1	Prm4p
NP_015170.1	Kip2p
NP_015171.1	Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates
NP_015172.1	Rad53p
NP_878180.1	Ypl152w-ap
NP_015173.1	Rrd2p
NP_015174.1	Splicing factor that is found in the Cef1p subcomplex of the spliceosome
NP_015175.1	Ypl150wp
NP_015176.1	Conserved autophagy-related protein that undergoes conjugation with Atg12p and then associates with Atg16p to form a cytosolic complex essential for autophagosome formation
NP_015177.2	Ppt2p
NP_015178.1	Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins
NP_015179.1	Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p; null mutant is viable but growth is severely impaired
NP_015180.1	Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex
NP_015181.1	Poc4p
NP_015182.1	Rpl33ap
NP_015184.1	Ypl141cp
NP_015185.1	Mkk2p
NP_015186.1	Ume1p
NP_015187.1	Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein
NP_015188.1	Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
NP_015190.1	Isu1p
NP_015191.1	Odc1p
NP_015192.1	Zinc cluster transcriptional activator involved in conferring resistance to ketoconazole
NP_015193.1	Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p
NP_015194.1	Rpl5p
NP_015195.1	Spo19p
NP_015196.1	Taf14p
NP_015197.1	Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation
NP_015198.1	Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation
NP_015199.1	U3 snoRNP protein, component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA
NP_015200.1	Karyopherin with a role in the assembly or export of 60S ribosomal subunits
NP_015201.1	Spc29p
NP_015202.1	Rny1p
NP_015203.1	Tfb2p
NP_015204.1	Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p
NP_015205.1	Vps30p
NP_878181.1	Ypl119c-ap
NP_015206.1	Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs
NP_015207.1	Mrp51p
NP_015208.1	Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase), catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability
NP_015209.1	Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats
NP_015210.1	Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly
NP_015212.1	Ypl113cp
NP_015213.1	Pex25p
NP_015214.1	Car1p
NP_015215.1	Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes
NP_015216.3	Ypl109cp
NP_015217.1	Ypl108wp
NP_015218.1	Ypl107wp
NP_015219.1	Sse1p
NP_015220.1	Ypl105cp
NP_015221.1	Msd1p
NP_015222.1	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
NP_015224.1	Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity
NP_015225.1	Phosphoinositide binding protein required for vesicle formation in the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein
NP_015226.1	Protein of unknown function;non-tagged protein detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media
NP_015227.1	Protein required for growth of cells lacking the mitochondrial genome
NP_015228.1	Msy1p
NP_690846.1	Eri1p
NP_015229.1	Png1p
NP_015230.1	Eeb1p
NP_015231.2	Sec62p
NP_015232.1	Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins
NP_015233.1	Ssu1p
NP_015234.1	Glr1p
NP_015235.1	Rps6ap
NP_015236.1	Rlm1p
NP_015237.1	Ypl088wp
NP_015238.1	Ydc1p
NP_015239.1	Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin
NP_015240.1	Sec16p
NP_015241.1	Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes
NP_015242.1	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p
NP_015243.1	Mot1p
NP_015244.1	Rps9ap
NP_015246.1	Rpl21bp
NP_015247.1	Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
NP_015248.1	Ypl077cp
NP_015249.1	Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein
NP_015250.1	Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
NP_015251.1	Yta6p
NP_015253.1	Ubp16p
NP_015254.1	Ypl071cp
NP_015255.1	Muk1p
NP_015256.1	Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic
NP_015257.1	Ypl068cp
NP_015258.1	Ypl067cp
NP_015259.1	Ypl066wp
NP_015260.1	Vps28p
NP_015261.1	Cwc27p
NP_015262.1	Tim50p
NP_015264.1	Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress
NP_015265.1	Mitochondrial inner membrane magnesium transporter, involved in maintenance of magnesium concentrations inside mitochondria; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p
NP_015266.1	Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p
NP_015267.1	Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity
NP_015268.1	Sur1p
NP_015269.1	Ypl056cp
NP_015270.1	Protein of unknown function; null mutant forms abnormally large cells
NP_015271.1	Zinc-finger protein of unknown function
NP_015272.1	Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family
NP_015273.2	Regulator of ornithine decarboxylase (Spe1p), antizyme that binds to Spe1p to regulate ubiquitin-independent degradation; ribosomal frameshifting during synthesis of Oaz1p and its ubiquitin-mediated degradation are both polyamine-regulated
NP_015274.1	GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor
NP_015275.1	Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation
NP_015276.1	Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription
NP_015277.1	Nuclear protein required for transcription of MXR1; binds the MXR1 promoter in the presence of other nuclear factors; binds calcium and phospholipids; has similarity to translational cofactor EF-1 gamma
NP_015278.1	Sgf11p
NP_015279.1	Elongin C, forms heterodimer with Ela1p that participates in transcription elongation; required for ubiquitin-dependent degradation of the RNA Polymerase II subunit RPO21; expression dramatically upregulated during sporulation
NP_015280.1	Vps16p
NP_015282.1	Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs)
NP_015283.1	Ssn3p
NP_015284.1	Ypl041cp
NP_015285.1	Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth
NP_015286.1	Ypl039wp
NP_878182.1	Ypl038w-ap
NP_015287.1	Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p
NP_015288.1	Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
NP_015289.1	Pma2p
NP_015291.1	Ypl034wp
NP_015292.1	Ypl033cp
NP_015293.1	Svl3p
NP_015294.1	Pho85p
NP_015295.1	Trm44p
NP_015296.1	Suv3p
NP_015297.1	Erg10p
NP_015298.1	Sma1p
NP_015299.1	Sks1p
NP_015301.1	Rmi1p
NP_015302.1	Met12p
NP_015303.1	Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein
NP_015304.1	Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p
NP_015305.1	Ulp1p
NP_015306.1	Vtc3p
NP_015307.1	Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly
NP_015308.1	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; null mutant displays increased levels of spontaneous Rad52 foci
NP_015309.1	Swi1p
NP_015310.1	Hst2p
NP_015311.1	Ypl014wp
NP_015312.1	Mrps16p
NP_015313.1	Rrp12p
NP_015314.1	Taf3p
NP_015315.1	Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER
NP_015316.1	Ypl009cp
NP_015317.1	Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p
NP_015318.1	Tfc8p
NP_015319.1	Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein
NP_015320.1	Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex
NP_015321.1	Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways
NP_015322.1	Ula1p
NP_015323.1	Snf8p
NP_015324.1	Hat1p
NP_015325.1	Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate
NP_015326.1	Pdh1p
NP_015328.1	Ypr003cp
NP_015329.1	Protein with similarity to mammalian electron transfer flavoprotein complex subunit ETF-alpha; interacts with yeast frataxin Yfh1p; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
NP_015330.1	Hal1p
NP_015331.1	Icl2p
NP_015332.1	Rec8p
NP_015333.1	Transcriptional activator involved in the transcription of TPO2, HSP30 and other genes encoding membrane stress proteins; involved in adaptation to weak acid stress
NP_015334.1	Sut2p
NP_015335.1	Rpa135p
NP_001091638.1	Ypr010c-ap
NP_015336.1	Ypr011cp
NP_015338.1	Ypr013cp
NP_015340.1	Ypr015cp
NP_015341.1	Tif6p
NP_015342.1	Guanine nucleotide dissociation stimulator for Sec4p, functions in the post-Golgi secretory pathway; binds zinc, found both on membranes and in the cytosol
NP_015343.1	Rlf2p
NP_015344.1	Mcm4p
NP_015345.1	Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex
NP_015346.1	Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis
NP_015347.1	Ypr022cp
NP_015348.1	Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3
NP_015349.1	Yme1p
NP_015350.1	Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters
NP_015351.1	Ath1p
NP_015352.1	Ypr027cp
NP_015353.1	Yop1p
NP_015354.1	Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport
NP_015355.1	Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate
NP_015356.1	Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3
NP_015357.1	Sro7p
NP_015358.1	Hts1p
NP_015359.1	Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation
NP_015360.1	Glutamine synthetase (GS), synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation
NP_015361.1	Vma13p
NP_690847.1	Ypr036w-ap
NP_015362.1	Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER
NP_015365.1	Tip41p
NP_015366.1	Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation
NP_015367.1	Puf2p
NP_015368.1	Rpl43ap
NP_015370.1	Mni2p
NP_015371.1	Protein involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA
NP_015372.2	Msf1p
NP_015373.1	Tah18p
NP_015374.1	Peripheral membrane protein required for delivery of aminopeptidase I (Lap4p) to the vacuole in the cytoplasm-to-vacuole targeting pathway; also required for peroxisomal degradation (pexophagy)
NP_015376.1	Mak3p
NP_015377.1	Nhp6ap
NP_015379.1	Smk1p
NP_015380.1	Sec8p
NP_015381.1	Tfb4p
NP_015382.1	snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed
NP_015383.1	Ymc1p
NP_015385.1	Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis
NP_015386.1	Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae
NP_015387.1	Fcy1p
NP_015388.1	Ypr063cp
NP_015390.1	Rox1p
NP_015391.1	Uba3p
NP_015392.1	Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations
NP_015393.1	Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; deletion results in increased histone acetylation at rDNA repeats; interacts with the Tup1p-Ssn6p corepressor complex
NP_015394.1	Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells
NP_015395.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
NP_015396.1	Ypr071wp
NP_015397.1	Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation
NP_015398.1	Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine
NP_015399.1	Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
NP_015400.1	Opy2p
NP_015403.1	Ypr078cp
NP_015404.1	Mrl1p
NP_015405.1	Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes
NP_015406.1	Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for Grs1p; possible pseudogene that is expressed at very low levels
NP_015407.1	Dib1p
NP_015408.1	Protein required for normal mitochondrial morphology and inheritance
NP_015409.1	Ypr084wp
NP_015410.2	Ypr085cp
NP_015411.1	Transcription factor TFIIB, a general transcription factor required for transcription initiation and start site selection by RNA polymerase II
NP_015413.1	Srp54p
NP_015414.2	Ypr089wp
NP_015416.1	Ypr091cp
NP_015418.2	Protein involved in a putative alcohol-responsive signaling pathway; accumulates in the nucleus under alcohol stress; contains a Ring/PHD finger domain
NP_015419.1	Zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance
NP_015420.1	Syt1p
NP_015421.1	Ypr096cp
NP_015422.1	Ypr097wp
NP_015423.2	Ypr098cp
NP_015425.1	Mrpl51p
NP_015426.1	Snt309p
NP_015427.1	Rpl11ap
NP_015428.1	Pre2p
NP_015429.1	Transcriptional activator with similarity to DNA-binding domain of Drosophila forkhead but unable to bind DNA in vitro; required for rRNA processing; isolated as a suppressor of splicing factor prp4
NP_015430.1	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
NP_015431.1	Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C
NP_015432.1	Yth1p
NP_015433.1	Rpn7p
NP_878183.1	Ypr108w-ap
NP_015434.1	Ypr109wp
NP_015435.1	Rpc40p
NP_015436.1	Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis
NP_015437.1	Mrd1p
NP_015438.1	Pis1p
NP_015439.1	Ypr114wp
NP_015440.1	Ypr115wp
NP_015441.1	Ypr116wp
NP_015442.1	Ypr117wp
NP_015443.1	Mri1p
NP_015444.1	Clb2p
NP_015445.1	Clb5p
NP_015446.1	Thi22p
NP_015447.1	Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone; required for axial budding pattern of haploid cells
NP_015449.1	High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels
NP_015450.1	Ylh47p
NP_015452.1	Ypr127wp
NP_015453.1	Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation
NP_015454.1	Scd6p
NP_015456.2	Nat3p
NP_015457.1	Rps23bp
NP_015458.1	Spn1p
NP_015459.1	Tom5p
NP_015460.1	Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions
NP_015461.1	Ctf4p
NP_015463.1	Rrp9p
NP_058191.1	Ypr137c-bp
NP_058192.1	Ypr137c-ap
NP_015464.1	Mep3p
NP_015465.1	Vps66p
NP_015466.1	Taz1p
NP_015467.1	Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate
NP_015469.1	Rrp15p
NP_015470.1	Nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits
NP_015471.1	Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
NP_001032572.1	Ypr145c-ap
NP_015473.1	Ypr147cp
NP_015474.1	Ypr148cp
NP_015475.1	Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)
NP_015477.1	Sue1p
NP_015478.1	Urn1p
NP_015479.2	Ypr153wp
NP_015480.1	Protein that induces appearance of [PIN+] prion when overproduced
NP_015481.1	Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p
NP_015482.1	Tpo3p
NP_015483.1	Ypr157wp
NP_015484.1	Ypr158wp
NP_058193.1	Ypr158w-bp
NP_058194.1	Ypr158w-ap
NP_058195.1	Ypr158c-dp
NP_058196.1	Ypr158c-cp
NP_015485.1	Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functionally redundant with Skn1p
NP_878184.1	Ypr159c-ap
NP_015486.1	Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway
NP_015487.1	Sgv1p
NP_015488.1	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
NP_015489.1	Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA
NP_015490.1	Protein likely involved in protection against replication-dependent DNA damage; mutants are sensitive to methyl methanesulfonate (MMS); implicated in regulation of Ty1 transposition
NP_015491.1	Rho1p
NP_015492.1	Mrp2p
NP_015493.1	Met16p
NP_015494.1	Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription
NP_015495.2	Nucleolar protein of unknown function, exhibits a physical interaction with Bre1p
NP_001106949.1	Ypr170w-bp
NP_015497.1	Bsp1p
NP_015498.1	Ypr172wp
NP_015499.1	Vps4p
NP_015500.1	Ypr174cp
NP_015501.2	Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate
NP_015502.1	Beta subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p
NP_015504.1	Splicing factor, component of the U4/U6-U5 snRNP complex
NP_015505.1	Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that contains an Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; has similarity to Hda2p
NP_015506.1	Nuclear protein that acts as a heterodimer with Uba2p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability
NP_015507.1	Sec23p
NP_015508.1	Smx3p
NP_015509.1	Dpm1p
NP_015510.1	Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria
NP_015511.1	Phosphorylated protein that interacts with Vac8p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway and autophagy
NP_015512.1	Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA
NP_015513.1	Rpo26p
NP_015514.1	Regulatory light chain for the type II myosin, Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring
NP_015515.1	Ski3p
NP_015516.1	Rpc82p
NP_015517.1	Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme
NP_015518.1	Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance
NP_015519.1	Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity
NP_015520.1	Opt2p
NP_015522.1	Ypr196wp
NP_015524.1	Sge1p
NP_015525.1	Transcriptional activator of the bZIP family, required for transcription of genes involved in resistance to arsenic compounds
NP_015526.1	Arsenate reductase required for arsenate resistance; converts arsenate to arsenite which can then be exported from cells by Arr3p
NP_015527.1	Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite
NP_015528.1	Ypr202wp
NP_015529.1	Ypr203wp
NP_015530.1	Ypr204wp