-- dump date 20120504_161014 -- class Genbank::CDS -- table cds_note -- id note YP_001156864.1 TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator, DnaA C-terminal domain; Chromosomal replication initiator, DnaA; SMART: AAA ATPase YP_001156866.1 TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_001156867.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_001156868.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001156869.1 PFAM: protein of unknown function DUF721 YP_001156871.1 TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001156872.1 negatively supercoils closed circular double-stranded DNA YP_001156874.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001156877.1 PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001156878.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001156879.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC, N-terminal domain YP_001156880.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001156883.1 PFAM: DSBA oxidoreductase YP_001156884.1 PFAM: Fe-S metabolism associated SufE YP_001156885.1 PFAM: CBS domain containing protein YP_001156886.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001156887.1 PFAM: regulatory protein, TetR YP_001156888.1 PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001156889.1 PFAM: pyruvate carboxyltransferase YP_001156890.1 PFAM: carboxyl transferase YP_001156891.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001156892.1 PFAM: helix-turn-helix domain protein; Tetratricopeptide TPR_4 YP_001156893.1 PFAM: regulatory protein, MarR YP_001156896.1 PFAM: PASTA domain containing protein YP_001156899.1 PFAM: helix-turn-helix domain protein YP_001156900.1 PFAM: protein of unknown function DUF397 YP_001156902.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Proprotein convertase, P; proteinase inhibitor I9, subtilisin propeptide YP_001156903.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF YP_001156904.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001156905.1 PFAM: Forkhead-associated protein YP_001156906.1 PFAM: Forkhead-associated protein YP_001156907.1 PFAM: protein phosphatase 2C domain protein YP_001156908.1 PFAM: cell cycle protein YP_001156909.1 PFAM: penicillin-binding protein, transpeptidase YP_001156910.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001156911.1 PFAM: protein kinase; PASTA domain containing protein; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001156912.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001156914.1 TIGRFAM: sortase family protein; PFAM: peptidase C60, sortase A and B YP_001156915.1 PFAM: protein of unknown function DUF881 YP_001156917.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001156918.1 PFAM: NLP/P60 protein YP_001156919.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001156920.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001156921.1 PFAM: phage integrase family protein YP_001156922.1 TIGRFAM: DNA binding domain, excisionase family YP_001156924.1 PFAM: C-5 cytosine-specific DNA methylase YP_001156932.1 PFAM: NUDIX hydrolase YP_001156935.1 PFAM: regulatory protein GntR, HTH YP_001156936.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001156940.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001156941.1 PFAM: aldehyde dehydrogenase YP_001156944.1 PFAM: amidohydrolase; Amidohydrolase 3 YP_001156945.1 PFAM: GCN5-related N-acetyltransferase YP_001156946.1 PFAM: alpha/beta hydrolase fold YP_001156947.1 PFAM: GCN5-related N-acetyltransferase YP_001156948.1 PFAM: luciferase family protein YP_001156949.1 PFAM: phosphoribosyltransferase YP_001156950.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A YP_001156951.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001156952.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001156954.1 PFAM: Phosphoglycerate mutase YP_001156955.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001156956.1 PFAM: ThiJ/PfpI domain protein YP_001156959.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein YP_001156960.1 PFAM: Allophanate hydrolase subunit 1 YP_001156961.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2 YP_001156962.1 PFAM: LamB/YcsF family protein YP_001156963.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; NHL repeat containing protein; Redoxin domain protein YP_001156966.1 PFAM: protein of unknown function DUF397 YP_001156967.1 PFAM: Eco57I restriction endonuclease YP_001156968.1 PFAM: BsuBIPstI restriction endonuclease domain protein YP_001156970.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001156971.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001156972.1 PFAM: dehydrogenase, E1 component YP_001156974.1 PFAM: protein of unknown function DUF805 YP_001156976.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001156977.1 PFAM: GrpE protein YP_001156978.1 TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein YP_001156979.1 PFAM: regulatory protein, MerR YP_001156982.1 PFAM: sodium/hydrogen exchanger YP_001156983.1 PFAM: TrkA-C domain protein YP_001156984.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001156987.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001156988.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001156989.1 PFAM: regulatory protein, ArsR YP_001156991.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_001156993.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001156996.1 PFAM: adenylosuccinate synthetase YP_001156997.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001156998.1 PFAM: major facilitator superfamily MFS_1 YP_001156999.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001157000.1 PFAM: Sterol-binding domain protein YP_001157001.1 PFAM: regulatory protein, TetR YP_001157003.1 PFAM: MaoC domain protein dehydratase YP_001157004.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001157005.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001157007.1 PFAM: UbiC transcription regulator-associated domain protein YP_001157008.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001157009.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001157010.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001157011.1 PFAM: protein of unknown function DUF74 YP_001157012.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001157013.1 TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS YP_001157014.1 TIGRFAM: phosphoribosylformylglycinamidine synthase I; PFAM: CobB/CobQ domain protein glutamine amidotransferase YP_001157015.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001157017.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001157018.1 TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001157019.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001157022.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001157024.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein, MerR YP_001157026.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001157027.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001157029.1 PFAM: Activator of Hsp90 ATPase 1 family protein YP_001157031.1 PFAM: glycosyl transferase, family 28 YP_001157033.1 PFAM: Abortive infection protein YP_001157034.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001157035.1 PFAM: copper resistance D domain protein YP_001157036.1 PFAM: DSBA oxidoreductase YP_001157037.1 PFAM: Vitamin K epoxide reductase YP_001157039.1 PFAM: major facilitator superfamily MFS_1 YP_001157040.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001157041.1 TIGRFAM: nitrate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001157042.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase, delta subunit YP_001157043.1 TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase, gamma subunit YP_001157044.1 PFAM: Carboxymuconolactone decarboxylase YP_001157045.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001157046.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001157047.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001157048.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001157049.1 PFAM: VanW family protein YP_001157050.1 PFAM: NUDIX hydrolase YP_001157056.1 PFAM: glycosyl transferase, group 1 YP_001157057.1 PFAM: acyltransferase 3 YP_001157059.1 PFAM: protein of unknown function DUF885 YP_001157060.1 PFAM: protein of unknown function DUF6, transmembrane YP_001157061.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001157062.1 PFAM: peptidase M23B YP_001157065.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001157066.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001157067.1 PFAM: O-methyltransferase, family 2; Methyltransferase type 12 YP_001157068.1 PFAM: protein of unknown function DUF307 YP_001157072.1 PFAM: aminoglycoside phosphotransferase YP_001157074.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001157076.1 TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001157077.1 PFAM: conserved hypothetical protein 103 YP_001157078.1 TIGRFAM: recombination protein RecR; PFAM: RecR protein; TOPRIM domain protein; SMART: Toprim sub domain protein YP_001157079.1 PFAM: extracellular solute-binding protein, family 5 YP_001157080.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001157081.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001157082.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001157083.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001157086.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001157087.1 TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain YP_001157088.1 PFAM: nitroreductase YP_001157089.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001157090.1 TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_001157091.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein YP_001157092.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein YP_001157093.1 TIGRFAM: helicase, RecD/TraA family; SMART: AAA ATPase YP_001157095.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001157096.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001157097.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001157100.1 PFAM: amino acid permease-associated region; Amino acid transporter, transmembrane YP_001157101.1 PFAM: glycosyl transferase, family 28; Glycosyltransferase 28, C-terminal domain YP_001157103.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001157104.1 PFAM: amine oxidase; FAD dependent oxidoreductase YP_001157105.1 PFAM: TrkA-N domain protein; TrkA-C domain protein YP_001157106.1 PFAM: phosphoesterase, PA-phosphatase related YP_001157108.1 TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; Amidohydrolase 3 YP_001157109.1 PFAM: ROK family protein YP_001157110.1 PFAM: sugar isomerase (SIS) YP_001157111.1 PFAM: regulatory protein, DeoR YP_001157112.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157116.1 PFAM: GCN5-related N-acetyltransferase YP_001157117.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001157118.1 PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001157119.1 PFAM: alpha/beta hydrolase fold; peptidase S15; ABC transporter related; X-Pro dipeptidyl-peptidase C-terminal domain protein; SMART: AAA ATPase YP_001157122.1 PFAM: regulatory protein GntR, HTH; Helix-turn-helix, type 11 domain protein YP_001157123.1 TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: surface protein from Gram-positive cocci, anchor region YP_001157124.1 PFAM: regulatory protein, TetR YP_001157125.1 PFAM: acyltransferase 3 YP_001157126.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001157127.1 PFAM: GCN5-related N-acetyltransferase YP_001157128.1 TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: aldehyde dehydrogenase YP_001157129.1 PFAM: protein of unknown function DUF574 YP_001157130.1 PFAM: GCN5-related N-acetyltransferase YP_001157131.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001157132.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001157133.1 PFAM: GCN5-related N-acetyltransferase YP_001157134.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001157135.1 PFAM: FAD dependent oxidoreductase YP_001157136.1 PFAM: FAD linked oxidase domain protein YP_001157138.1 PFAM: aminotransferase, class V YP_001157141.1 PFAM: chaperonin Cpn10 YP_001157142.1 PFAM: protein of unknown function UPF0118 YP_001157143.1 SMART: helicase c2 YP_001157144.1 PFAM: protein of unknown function DUF402 YP_001157145.1 PFAM: protein of unknown function DUF47 YP_001157146.1 PFAM: phosphate transporter YP_001157147.1 PFAM: NUDIX hydrolase YP_001157148.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein YP_001157149.1 TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001157150.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component YP_001157151.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001157152.1 TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001157153.1 PFAM: transcriptional regulator domain protein YP_001157154.1 PFAM: GCN5-related N-acetyltransferase YP_001157155.1 PFAM: polysaccharide deacetylase YP_001157156.1 PFAM: transcriptional regulator domain protein YP_001157159.1 PFAM: Rhodanese domain protein YP_001157160.1 PFAM: protein of unknown function DUF1416 YP_001157162.1 PFAM: regulatory protein GntR, HTH YP_001157164.1 PFAM: pentapeptide repeat protein YP_001157166.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein YP_001157168.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Kelch repeat-containing protein; Kelch repeat protein YP_001157169.1 PFAM: transcriptional regulator domain protein YP_001157171.1 PFAM: beta-lactamase domain protein YP_001157174.1 PFAM: aminotransferase, class IV YP_001157175.1 PFAM: ferric-uptake regulator YP_001157176.1 PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001157177.1 PFAM: protein of unknown function DUF849 YP_001157178.1 PFAM: L-asparaginase II YP_001157179.1 PFAM: helix-turn-helix domain protein YP_001157182.1 PFAM: alpha/beta hydrolase fold YP_001157183.1 PFAM: Polymorphic membrane protein, Chlamydia YP_001157185.1 PFAM: protein of unknown function DUF540 YP_001157186.1 PFAM: GCN5-related N-acetyltransferase YP_001157187.1 PFAM: Endoribonuclease L-PSP YP_001157188.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001157189.1 PFAM: glycoside hydrolase, family 1 YP_001157190.1 PFAM: protein of unknown function DUF1503 YP_001157191.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001157193.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001157194.1 PFAM: glycosyl transferase, group 1 YP_001157197.1 PFAM: major facilitator superfamily MFS_1 YP_001157198.1 TIGRFAM: phosphoglycerate mutase 1 family; PFAM: Phosphoglycerate mutase YP_001157199.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001157200.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001157202.1 PFAM: Ppx/GppA phosphatase YP_001157203.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001157204.1 PFAM: protein of unknown function DUF1470 YP_001157205.1 PFAM: Proline dehydrogenase YP_001157206.1 TIGRFAM: DNA binding domain, excisionase family YP_001157207.1 PFAM: Protein of unknown function DUF1713 YP_001157208.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR YP_001157209.1 PFAM: phospholipid/glycerol acyltransferase YP_001157210.1 PFAM: major facilitator superfamily MFS_1 YP_001157211.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001157213.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001157214.1 PFAM: glutaredoxin 2 YP_001157215.1 PFAM: Haloacid dehalogenase domain protein hydrolase YP_001157216.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001157217.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001157218.1 modulates transcription in response to the NADH/NAD(+) redox state YP_001157219.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001157220.1 TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase YP_001157221.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4 YP_001157222.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001157223.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001157224.1 PFAM: GCN5-related N-acetyltransferase YP_001157226.1 TIGRFAM: putative regulatory protein, FmdB family YP_001157228.1 PFAM: Methyltransferase type 11 YP_001157231.1 PFAM: Integrase, catalytic region YP_001157232.1 PFAM: inositol monophosphatase YP_001157235.1 PFAM: TrkA-N domain protein; TrkA-C domain protein YP_001157236.1 PFAM: cation transporter YP_001157237.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001157239.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001157240.1 SMART: helix-turn-helix domain protein YP_001157242.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001157244.1 PFAM: regulatory protein, TetR YP_001157246.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation YP_001157248.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001157249.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001157250.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001157251.1 PFAM: major facilitator superfamily MFS_1 YP_001157252.1 PFAM: aminotransferase, class V; Pyridoxal-dependent decarboxylase YP_001157253.1 TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001157254.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001157255.1 PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit YP_001157256.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001157257.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane YP_001157258.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001157259.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001157260.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157263.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001157264.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001157265.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001157266.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001157267.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001157268.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001157269.1 PFAM: peptidase M48, Ste24p YP_001157270.1 PFAM: protein of unknown function DUF1275 YP_001157271.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001157272.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001157276.1 PFAM: major facilitator superfamily MFS_1 YP_001157279.1 PFAM: Xanthine/uracil/vitamin C permease YP_001157280.1 PFAM: regulatory protein, MarR YP_001157281.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1 YP_001157283.1 TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase YP_001157285.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_001157286.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle YP_001157287.1 TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001157288.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1 YP_001157289.1 PFAM: Aldose 1-epimerase YP_001157290.1 PFAM: nitroreductase YP_001157292.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001157293.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001157294.1 PFAM: ABC-2 type transporter YP_001157295.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157296.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001157297.1 PFAM: glycosyl transferase, family 2; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001157298.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157300.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001157301.1 PFAM: glycoside hydrolase, family 65 domain protein; glycoside hydrolase family 65, central catalytic; glycoside hydrolase family 65 domain protein YP_001157302.1 PFAM: dienelactone hydrolase YP_001157305.1 PFAM: carbonic anhydrase YP_001157307.1 PFAM: YibE/F family protein YP_001157308.1 PFAM: protein of unknown function DUF156 YP_001157309.1 PFAM: Heavy metal transport/detoxification protein YP_001157311.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001157312.1 PFAM: sodium/calcium exchanger membrane region YP_001157313.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001157315.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001157317.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157320.1 SMART: transcription factor jumonji, jmjC domain protein YP_001157321.1 PFAM: aminotransferase, class I and II YP_001157322.1 PFAM: HpcH/HpaI aldolase YP_001157323.1 PFAM: ornithine cyclodeaminase/mu-crystallin YP_001157325.1 PFAM: MaoC domain protein dehydratase YP_001157326.1 PFAM: peptidase M24; peptidase M24B, X-Pro dipeptidase/aminopeptidase domain protein YP_001157330.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; Parallel beta-helix repeat YP_001157334.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001157337.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase YP_001157340.1 PFAM: protein of unknown function DUF690 YP_001157342.1 PFAM: protein of unknown function DUF909 YP_001157343.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001157355.1 PFAM: transcriptional regulator domain protein; transcriptional activator domain; Tetratricopeptide TPR_4 YP_001157356.1 PFAM: FAD dependent oxidoreductase YP_001157357.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001157358.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein YP_001157359.1 PFAM: regulatory protein, IclR YP_001157360.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY YP_001157363.1 PFAM: aldo/keto reductase YP_001157365.1 PFAM: beta-lactamase YP_001157366.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157372.1 PFAM: helix-turn-helix domain protein YP_001157374.1 SMART: helix-turn-helix domain protein YP_001157375.1 PFAM: protein of unknown function DUF397 YP_001157382.1 PFAM: Recombination endonuclease VII YP_001157390.1 PFAM: Peptidoglycan-binding domain 1 protein YP_001157391.1 PFAM: Fibronectin, type III domain protein YP_001157419.1 PFAM: phage integrase family protein YP_001157425.1 PFAM: DNA mismatch endonuclease vsr YP_001157427.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase YP_001157441.1 TIGRFAM: selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001157442.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001157443.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; translation elongation factor, selenocysteine-specific YP_001157444.1 PFAM: transposase, mutator type YP_001157447.1 PFAM: nitroreductase YP_001157448.1 PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; WD40 domain protein beta Propeller YP_001157449.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001157451.1 PFAM: FG-GAP repeat protein YP_001157452.1 PFAM: L-seryl-tRNA selenium transferase YP_001157456.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR YP_001157458.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001157459.1 SMART: PBS lyase HEAT domain protein repeat-containing protein YP_001157460.1 PFAM: ABC-1 domain protein YP_001157461.1 PFAM: cytochrome P450 YP_001157462.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001157463.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001157468.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001157472.1 PFAM: phosphoesterase, PA-phosphatase related YP_001157473.1 PFAM: transcriptional regulator PadR family protein YP_001157474.1 PFAM: FG-GAP repeat protein YP_001157475.1 TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001157476.1 PFAM: ABC-2 type transporter YP_001157477.1 PFAM: protein of unknown function DUF1486 YP_001157478.1 PFAM: FG-GAP repeat protein YP_001157479.1 PFAM: alpha/beta hydrolase fold YP_001157480.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001157481.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001157482.1 PFAM: glycosyl hydrolase, BNR repeat-containing protein YP_001157483.1 PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001157485.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001157489.1 PFAM: major facilitator superfamily MFS_1 YP_001157490.1 PFAM: FAD dependent oxidoreductase YP_001157491.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; major intrinsic protein YP_001157492.1 PFAM: beta-lactamase YP_001157493.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001157494.1 PFAM: protein of unknown function DUF6, transmembrane YP_001157496.1 PFAM: protein of unknown function UPF0027 YP_001157498.1 PFAM: aminoglycoside phosphotransferase YP_001157499.1 PFAM: Methyltransferase type 11 YP_001157500.1 PFAM: protein of unknown function DUF397 YP_001157501.1 SMART: helix-turn-helix domain protein YP_001157502.1 PFAM: polysaccharide deacetylase YP_001157509.1 PFAM: LuxS protein YP_001157511.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1 YP_001157512.1 PFAM: regulatory protein, AsnC/Lrp family YP_001157513.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein YP_001157514.1 PFAM: major facilitator superfamily MFS_1 YP_001157515.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein YP_001157516.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001157517.1 PFAM: glycoside hydrolase 15-related YP_001157518.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001157519.1 PFAM: regulatory protein, TetR; Tetracyclin repressor domain protein YP_001157520.1 PFAM: alpha/beta hydrolase fold YP_001157521.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001157523.1 PFAM: Endoribonuclease L-PSP YP_001157524.1 PFAM: transcriptional regulator domain protein; transcriptional activator domain YP_001157525.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase YP_001157526.1 PFAM: major facilitator superfamily MFS_1 YP_001157528.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding YP_001157529.1 PFAM: Thioesterase YP_001157530.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001157533.1 catalyzes the formation of L-tryptophan from indole and L-serine YP_001157535.1 PFAM: AMP-dependent synthetase and ligase YP_001157536.1 PFAM: Orn/DAP/Arg decarboxylase 2 YP_001157537.1 PFAM: phosphopantetheine-binding YP_001157538.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001157539.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001157540.1 PFAM: 4'-phosphopantetheinyl transferase YP_001157542.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase YP_001157543.1 PFAM: Thioesterase; condensation domain protein YP_001157545.1 PFAM: argininosuccinate synthase YP_001157546.1 PFAM: formyl transferase domain protein YP_001157548.1 PFAM: flavin reductase domain protein, FMN-binding YP_001157549.1 PFAM: Auxin Efflux Carrier YP_001157550.1 PFAM: peptidase S14, ClpP YP_001157551.1 PFAM: helix-turn-helix domain protein YP_001157552.1 PFAM: TrkA-N domain protein; Ion transport 2 domain protein YP_001157553.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding YP_001157554.1 PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein YP_001157556.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_001157557.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001157560.1 TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001157562.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001157563.1 PFAM: PaaX domain protein; PaaX domain protein, C-terminal domain YP_001157565.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein YP_001157566.1 PFAM: O-methyltransferase, family 3 YP_001157567.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein YP_001157570.1 PFAM: protein of unknown function DUF59 YP_001157571.1 PFAM: protein of unknown function DUF1003 YP_001157572.1 PFAM: CBS domain containing protein; MgtE intracellular region YP_001157573.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001157575.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001157576.1 PFAM: protein of unknown function DUF6, transmembrane YP_001157577.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001157578.1 PFAM: HpcH/HpaI aldolase YP_001157580.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001157582.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001157583.1 PFAM: CoA-binding domain protein YP_001157584.1 PFAM: Radical SAM domain protein YP_001157585.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001157586.1 PFAM: MaoC domain protein dehydratase YP_001157588.1 PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001157590.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001157591.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001157593.1 PFAM: ferric-uptake regulator YP_001157596.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001157597.1 TIGRFAM: putative regulatory protein, FmdB family YP_001157598.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase YP_001157599.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; histidine kinase, HAMP region domain protein YP_001157600.1 PFAM: Nucleotidyl transferase YP_001157601.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001157602.1 PFAM: GCN5-related N-acetyltransferase YP_001157604.1 PFAM: phage integrase family protein YP_001157605.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157607.1 PFAM: ornithine cyclodeaminase/mu-crystallin YP_001157610.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001157611.1 PFAM: protein of unknown function DUF664 YP_001157612.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein YP_001157613.1 PFAM: Roadblock/LC7 family protein YP_001157614.1 PFAM: Extracellular ligand-binding receptor YP_001157615.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001157616.1 PFAM: inner-membrane translocator YP_001157617.1 PFAM: inner-membrane translocator YP_001157618.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157619.1 PFAM: lipase, class 2 YP_001157620.1 PFAM: Alkaline phosphatase YP_001157621.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_001157623.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001157625.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001157626.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001157627.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001157628.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001157629.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001157631.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase YP_001157632.1 PFAM: 4'-phosphopantetheinyl transferase YP_001157633.1 PFAM: glycosyl transferase, family 39 YP_001157634.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001157635.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001157636.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001157637.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001157638.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis YP_001157639.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157642.1 PFAM: regulatory protein, TetR YP_001157643.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001157644.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001157645.1 TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: ribosomal protein L25 YP_001157646.1 PFAM: peptidyl-tRNA hydrolase YP_001157647.1 PFAM: inositol monophosphatase YP_001157648.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001157649.1 TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001157650.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001157651.1 PFAM: CBS domain containing protein; transporter-associated region YP_001157652.1 TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib YP_001157653.1 PFAM: 2',5' RNA ligase YP_001157654.1 PFAM: ribonuclease BN YP_001157656.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001157657.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001157658.1 PFAM: extracellular solute-binding protein, family 1 YP_001157659.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001157660.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001157662.1 PFAM: basic membrane lipoprotein YP_001157663.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001157664.1 PFAM: inner-membrane translocator YP_001157665.1 PFAM: inner-membrane translocator YP_001157666.1 TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding YP_001157667.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001157669.1 PFAM: Methyltransferase type 11 YP_001157670.1 catalyzes the formation of inosine from adenosine YP_001157671.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; Nitrate and nitrite sensing domain protein YP_001157672.1 PFAM: Roadblock/LC7 family protein YP_001157673.1 PFAM: protein of unknown function DUF742 YP_001157674.1 PFAM: protein of unknown function, ATP binding YP_001157677.1 TIGRFAM: ABC transporter, transmembrane region, type 1; PFAM: ABC transporter related; SMART: AAA ATPase YP_001157678.1 TIGRFAM: ABC transporter, transmembrane region, type 1; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001157679.1 PFAM: peptidase M48, Ste24p; peptidase M56, BlaR1 YP_001157680.1 PFAM: Penicillinase repressor YP_001157682.1 PFAM: aldehyde dehydrogenase YP_001157683.1 TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase YP_001157684.1 TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001157685.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001157686.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001157687.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase YP_001157688.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20 YP_001157689.1 PFAM: beta-lactamase domain protein YP_001157692.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity YP_001157694.1 PFAM: GCN5-related N-acetyltransferase YP_001157695.1 PFAM: helix-turn-helix domain protein YP_001157696.1 PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein YP_001157697.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001157698.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001157699.1 PFAM: DoxX family protein YP_001157700.1 PFAM: regulatory protein, TetR YP_001157701.1 PFAM: regulatory protein, MarR YP_001157702.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001157703.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001157704.1 PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001157705.1 PFAM: O-methyltransferase, family 3 YP_001157706.1 TIGRFAM: maf protein; PFAM: Maf family protein YP_001157707.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001157709.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001157711.1 PFAM: carboxyl transferase YP_001157712.1 TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase YP_001157713.1 PFAM: membrane-flanked domain YP_001157714.1 PFAM: GtrA family protein YP_001157715.1 PFAM: GtrA family protein YP_001157716.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_001157717.1 TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001157718.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001157719.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: trehalose-phosphatase YP_001157721.1 PFAM: helix-turn-helix domain protein YP_001157725.1 PFAM: Rhomboid family protein YP_001157726.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein YP_001157727.1 PFAM: regulatory protein, TetR YP_001157728.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase YP_001157729.1 PFAM: protein of unknown function DUF606 YP_001157730.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001157732.1 PFAM: Exonuclease VII, small subunit YP_001157733.1 TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit; nucleic acid binding, OB-fold, tRNA/helicase-type YP_001157734.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001157736.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase domain protein YP_001157737.1 PFAM: protein of unknown function DUF195 YP_001157738.1 PFAM: phosphoenolpyruvate carboxylase YP_001157739.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001157741.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001157745.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001157746.1 PFAM: Septum formation initiator YP_001157747.1 PFAM: protein of unknown function DUF501 YP_001157748.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis YP_001157749.1 PFAM: Ppx/GppA phosphatase YP_001157750.1 PFAM: transcriptional regulator PadR family protein YP_001157753.1 PFAM: dienelactone hydrolase YP_001157754.1 PFAM: Uracil-DNA glycosylase superfamily YP_001157757.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001157758.1 PFAM: protein of unknown function DUF58 YP_001157760.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001157761.1 PFAM: protein of unknown function DUF1112 YP_001157763.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001157764.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001157765.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001157766.1 PFAM: protein of unknown function DUF1232 YP_001157767.1 TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001157768.1 PFAM: GCN5-related N-acetyltransferase YP_001157769.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001157770.1 PFAM: peptidase M20; peptidase M42 family protein YP_001157771.1 PFAM: GCN5-related N-acetyltransferase YP_001157772.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase YP_001157773.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001157774.1 PFAM: histidine triad (HIT) protein YP_001157775.1 PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001157776.1 PFAM: Amidase YP_001157777.1 catalyzes the formation of 2-oxobutanoate from L-threonine YP_001157778.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein YP_001157780.1 PFAM: LmbE family protein YP_001157782.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001157783.1 PFAM: B3/4 domain protein YP_001157784.1 PFAM: protein of unknown function DUF255 YP_001157785.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp YP_001157786.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001157788.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase YP_001157789.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001157791.1 PFAM: thioesterase superfamily protein YP_001157792.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase YP_001157794.1 PFAM: glycosyl transferase, group 1 YP_001157795.1 PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase YP_001157796.1 PFAM: NUDIX hydrolase YP_001157798.1 TIGRFAM: F420-dependent oxidoreductase, putative; PFAM: protein of unknown function DUF129 YP_001157799.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) YP_001157801.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis YP_001157802.1 PFAM: transcription factor WhiB YP_001157805.1 PFAM: aminotransferase class-III YP_001157806.1 PFAM: regulatory protein, AsnC/Lrp family YP_001157809.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001157811.1 PFAM: protein of unknown function DUF779 YP_001157812.1 PFAM: aldehyde dehydrogenase YP_001157813.1 PFAM: transcriptional regulator domain protein; GAF domain protein YP_001157814.1 PFAM: aldehyde dehydrogenase YP_001157816.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001157818.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001157819.1 TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase, type I YP_001157820.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001157821.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001157822.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001157825.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA YP_001157826.1 PFAM: GCN5-related N-acetyltransferase YP_001157827.1 TIGRFAM: preprotein translocase, SecA subunit; PFAM: helicase domain protein; SEC-C motif domain protein; SecA DEAD domain protein; SecA Wing and Scaffold; SecA preprotein cross-linking region YP_001157829.1 TIGRFAM: DNA binding domain, excisionase family YP_001157832.1 TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase YP_001157833.1 PFAM: transcriptional regulator PadR family protein YP_001157834.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001157835.1 TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001157836.1 PFAM: protein of unknown function DUF214 YP_001157837.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001157839.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate YP_001157840.1 PFAM: protein of unknown function DUF179 YP_001157841.1 TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin, Txe/YoeB YP_001157842.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001157844.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001157846.1 PFAM: protein of unknown function DUF397 YP_001157847.1 PFAM: transposase, IS4 family protein YP_001157850.1 PFAM: cell divisionFtsK/SpoIIIE YP_001157851.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196 YP_001157852.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48 YP_001157853.1 PFAM: protein of unknown function DUF83 YP_001157854.1 TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001157855.1 TIGRFAM: CRISPR-associated protein Cas5 YP_001157856.1 TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, DevR family YP_001157858.1 TIGRFAM: CRISPR-associated protein Cas6 YP_001157860.1 PFAM: protein of unknown function DUF324 YP_001157861.1 PFAM: protein of unknown function DUF324 YP_001157865.1 PFAM: regulatory protein, MerR; Methyltransferase type 11; Methyltransferase type 12 YP_001157868.1 PFAM: 20S proteasome, A and B subunits YP_001157869.1 PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase YP_001157870.1 TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001157871.1 PFAM: alpha/beta hydrolase fold YP_001157872.1 PFAM: MbtH domain protein YP_001157873.1 PFAM: cytochrome P450 YP_001157874.1 PFAM: beta-ketoacyl synthase YP_001157875.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding YP_001157876.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; condensation domain protein; phosphopantetheine-binding YP_001157878.1 PFAM: protein of unknown function DUF62 YP_001157879.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001157881.1 PFAM: cyclase family protein YP_001157882.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001157883.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_001157884.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001157886.1 PFAM: MaoC domain protein dehydratase YP_001157887.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate YP_001157888.1 PFAM: DAHP synthetase, class II YP_001157889.1 PFAM: Stress responsive alpha-beta barrel domain protein YP_001157891.1 TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV YP_001157893.1 PFAM: ornithine cyclodeaminase/mu-crystallin YP_001157894.1 PFAM: protein of unknown function DUF1330 YP_001157895.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001157896.1 TIGRFAM: polymorphic outer membrane protein YP_001157900.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001157904.1 SMART: LamG domain protein jellyroll fold domain protein YP_001157905.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein YP_001157907.1 PFAM: helix-turn-helix domain protein YP_001157911.1 PFAM: regulatory protein, MerR YP_001157912.1 PFAM: protein of unknown function DUF1234 YP_001157914.1 PFAM: alpha/beta hydrolase fold YP_001157915.1 PFAM: alpha/beta hydrolase fold; Epoxide hydrolase domain protein YP_001157916.1 PFAM: Helix-turn-helix, type 11 domain protein YP_001157918.1 PFAM: major facilitator superfamily MFS_1 YP_001157919.1 PFAM: GCN5-related N-acetyltransferase YP_001157920.1 PFAM: regulatory protein, TetR YP_001157921.1 PFAM: aldo/keto reductase YP_001157922.1 PFAM: GCN5-related N-acetyltransferase YP_001157924.1 PFAM: Ricin B lectin YP_001157925.1 PFAM: FAD linked oxidase domain protein YP_001157926.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001157927.1 PFAM: major facilitator superfamily MFS_1 YP_001157928.1 PFAM: regulatory protein, MerR; TipAS antibiotic-recognition domain protein YP_001157929.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001157934.1 PFAM: bifunctional deaminase-reductase domain protein YP_001157935.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001157938.1 PFAM: pentapeptide repeat protein YP_001157940.1 PFAM: HesB/YadR/YfhF-family protein YP_001157941.1 PFAM: glycoside hydrolase 15-related YP_001157942.1 PFAM: monooxygenase, FAD-binding YP_001157943.1 PFAM: cytochrome c oxidase, subunit I YP_001157944.1 PFAM: major facilitator superfamily MFS_1 YP_001157945.1 PFAM: isochorismatase hydrolase YP_001157946.1 TIGRFAM: putative nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase and related YP_001157947.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS YP_001157949.1 PFAM: Mov34/MPN/PAD-1 family protein YP_001157950.1 PFAM: thiamineS protein YP_001157951.1 TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001157952.1 PFAM: beta-lactamase domain protein YP_001157953.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001157954.1 TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein YP_001157955.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001157956.1 catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001157957.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001157958.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001157959.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001157960.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS) YP_001157961.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein YP_001157962.1 PFAM: GCN5-related N-acetyltransferase YP_001157963.1 PFAM: protein of unknown function DUF984 YP_001157964.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001157965.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein YP_001157967.1 TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein YP_001157968.1 TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001157969.1 PFAM: DSBA oxidoreductase YP_001157970.1 PFAM: DoxX family protein YP_001157971.1 PFAM: copper resistance protein CopC; copper resistance D domain protein YP_001157972.1 PFAM: nuclear export factor GLE1 YP_001157975.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001157977.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein YP_001157978.1 PFAM: NUDIX hydrolase YP_001157981.1 PFAM: protein of unknown function DUF397 YP_001157982.1 PFAM: helix-turn-helix domain protein YP_001157983.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001157984.1 PFAM: oxidoreductase domain protein; CoA-binding domain protein; Oxidoreductase, C-terminal domain YP_001157985.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP YP_001157988.1 PFAM: protein of unknown function DUF129 YP_001157989.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain YP_001157991.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001157993.1 PFAM: pentapeptide repeat protein YP_001157996.1 PFAM: protein of unknown function DUF129 YP_001157997.1 PFAM: Saccharopine dehydrogenase YP_001157998.1 PFAM: major facilitator superfamily MFS_1 YP_001158000.1 PFAM: Na+/H+ antiporter NhaA YP_001158001.1 PFAM: Integral membrane protein TerC YP_001158003.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001158004.1 PFAM: regulatory protein, MerR YP_001158006.1 PFAM: Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II YP_001158007.1 PFAM: regulatory protein, TetR YP_001158009.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001158010.1 PFAM: beta-lactamase domain protein YP_001158014.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001158015.1 PFAM: regulatory protein, TetR YP_001158017.1 PFAM: regulatory protein, TetR YP_001158018.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001158019.1 PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Methyltransferase type 11; Methyltransferase type 12 YP_001158020.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001158021.1 PFAM: regulatory protein, TetR YP_001158022.1 PFAM: AMP-dependent synthetase and ligase YP_001158023.1 PFAM: major facilitator superfamily MFS_1 YP_001158024.1 PFAM: regulator of chromosome condensation, RCC1 YP_001158025.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase YP_001158027.1 TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: regulator of chromosome condensation, RCC1 YP_001158029.1 PFAM: FAD linked oxidase domain protein YP_001158031.1 PFAM: glycoside hydrolase 15-related YP_001158032.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001158034.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001158035.1 PFAM: extracellular solute-binding protein, family 1 YP_001158036.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158037.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158038.1 PFAM: coagulation factor 5/8 type domain protein; glycoside hydrolase, family 85 YP_001158039.1 PFAM: glycoside hydrolase, family 38; glycosyl hydrolase 38 domain protein YP_001158041.1 TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: regulator of chromosome condensation, RCC1 YP_001158042.1 PFAM: protein of unknown function DUF72 YP_001158044.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001158045.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001158046.1 PFAM: GCN5-related N-acetyltransferase YP_001158047.1 PFAM: glycoside hydrolase, family 3 domain protein YP_001158048.1 PFAM: ROK family protein YP_001158049.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158050.1 PFAM: PfkB domain protein YP_001158051.1 PFAM: glycosyl transferase, group 1 YP_001158054.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001158055.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001158058.1 PFAM: electron transfer flavoprotein beta-subunit YP_001158059.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit YP_001158060.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein YP_001158061.1 PFAM: aminotransferase, class V YP_001158062.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001158063.1 PFAM: Methionine synthase, vitamin-B12 independent YP_001158065.1 TIGRFAM: DNA ligase, NAD-dependent; PFAM: helix-hairpin-helix motif; BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: Helix-hairpin-helix DNA-binding, class 1; NAD-dependent DNA ligase-like YP_001158066.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001158067.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001158068.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001158069.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001158070.1 PFAM: Transketolase domain protein YP_001158071.1 PFAM: metallophosphoesterase YP_001158073.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001158079.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001158080.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001158081.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate YP_001158082.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001158083.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001158084.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001158087.1 PFAM: isocitrate/isopropylmalate dehydrogenase YP_001158088.1 TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV YP_001158091.1 TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain YP_001158092.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001158093.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001158095.1 PFAM: von Willebrand factor, type A YP_001158096.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001158097.1 PFAM: Class I peptide chain release factor YP_001158100.1 PFAM: regulatory protein, TetR YP_001158101.1 PFAM: monooxygenase, FAD-binding YP_001158104.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001158105.1 PFAM: regulatory protein, IclR; sugar transporter superfamily protein YP_001158106.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001158107.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001158108.1 PFAM: histone family protein DNA-binding protein YP_001158109.1 PFAM: NUDIX hydrolase; Phosphoglycerate mutase YP_001158110.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001158113.1 PFAM: phospholipid/glycerol acyltransferase YP_001158114.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Ketopantoate reductase ApbA/PanE, N-terminal domain protein YP_001158115.1 catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine YP_001158116.1 PFAM: ROK family protein YP_001158117.1 PFAM: protein of unknown function DUF397 YP_001158118.1 PFAM: helix-turn-helix domain protein YP_001158120.1 TIGRFAM: D-alanine--D-alanine ligase; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; D-alanine--D-alanine ligase domain protein YP_001158122.1 PFAM: regulatory protein, AsnC/Lrp family YP_001158123.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001158124.1 PFAM: GCN5-related N-acetyltransferase YP_001158125.1 required for 70S ribosome assembly YP_001158126.1 PFAM: Dak phosphatase YP_001158127.1 catalyzes branch migration in Holliday junction intermediates YP_001158128.1 TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: surface protein from Gram-positive cocci, anchor region YP_001158129.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95 YP_001158130.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001158132.1 PFAM: protein of unknown function DUF177 YP_001158133.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001158134.1 PFAM: fatty acid synthesis plsX protein YP_001158135.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein YP_001158136.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001158137.1 PFAM: Allergen V5/Tpx-1 family protein YP_001158139.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein YP_001158140.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001158141.1 PFAM: protein of unknown function DUF664 YP_001158143.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001158144.1 PFAM: aminoglycoside phosphotransferase YP_001158146.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter YP_001158147.1 PFAM: nitrogen regulatory protein P-II YP_001158148.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK YP_001158149.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001158150.1 PFAM: amidohydrolase YP_001158151.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001158152.1 PFAM: protein of unknown function DUF402 YP_001158153.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001158155.1 Essential for efficient processing of 16S rRNA YP_001158156.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001158157.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001158158.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001158159.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001158160.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001158162.1 PFAM: peptidase M23B YP_001158164.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase YP_001158165.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001158166.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein YP_001158167.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase YP_001158168.1 PFAM: protein of unknown function UPF0102 YP_001158170.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001158171.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001158172.1 TIGRFAM: uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase YP_001158173.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001158174.1 PFAM: phosphatidate cytidylyltransferase YP_001158175.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001158178.1 PFAM: Rieske [2Fe-2S] domain protein YP_001158179.1 PFAM: FAD dependent oxidoreductase YP_001158182.1 PFAM: helix-turn-helix domain protein YP_001158184.1 PFAM: protein of unknown function DUF1271 YP_001158185.1 PFAM: cytochrome P450 YP_001158186.1 PFAM: protein of unknown function DUF214 YP_001158187.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158188.1 PFAM: transcriptional regulator PadR family protein YP_001158189.1 PFAM: Clp N terminal domain protein YP_001158190.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001158191.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001158192.1 PFAM: protein of unknown function UPF0074; regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001158195.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001158196.1 PFAM: peptidase M50 YP_001158197.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001158198.1 PFAM: GCN5-related N-acetyltransferase YP_001158199.1 PFAM: regulatory protein, MerR YP_001158202.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158203.1 PFAM: sodium:dicarboxylate symporter YP_001158204.1 TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase YP_001158205.1 PFAM: protein of unknown function DUF574 YP_001158206.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001158207.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001158208.1 PFAM: protein of unknown function DUF125, transmembrane YP_001158212.1 PFAM: protein of unknown function DUF150 YP_001158213.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001158214.1 PFAM: protein of unknown function DUF448 YP_001158215.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001158216.1 PFAM: protein of unknown function DUF503 YP_001158217.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001158218.1 PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1 YP_001158221.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE YP_001158223.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001158224.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase YP_001158225.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001158226.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001158227.1 PFAM: peptidase M16 domain protein YP_001158228.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001158229.1 PFAM: GCN5-related N-acetyltransferase YP_001158231.1 PFAM: protein of unknown function DUF1006 YP_001158233.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_001158234.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001158235.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001158238.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase YP_001158239.1 PFAM: small multidrug resistance protein YP_001158240.1 PFAM: ornithine cyclodeaminase/mu-crystallin YP_001158241.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme YliG; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB YP_001158242.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001158243.1 PFAM: CinA domain protein YP_001158244.1 PFAM: helix-turn-helix domain protein YP_001158245.1 PFAM: PspA/IM30 family protein YP_001158247.1 PFAM: Fibronectin, type III domain protein YP_001158248.1 PFAM: helix-turn-helix domain protein YP_001158249.1 PFAM: NAD(P)H dehydrogenase (quinone) YP_001158250.1 PFAM: protein of unknown function DUF62 YP_001158251.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like YP_001158253.1 PFAM: peptidase M20; peptidase M28 YP_001158254.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001158255.1 PFAM: CBS domain containing protein; protein of unknown function DUF21 YP_001158256.1 PFAM: SpoOM family protein YP_001158257.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001158258.1 PFAM: major facilitator superfamily MFS_1 YP_001158261.1 PFAM: protein of unknown function DUF397 YP_001158262.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001158263.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001158265.1 PFAM: MMPL domain protein YP_001158267.1 PFAM: major facilitator superfamily MFS_1 YP_001158269.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001158270.1 PFAM: regulatory protein RecX YP_001158271.1 TIGRFAM: metal dependent phophohydrolase; PFAM: KH, type 1, domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001158272.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001158273.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001158274.1 PFAM: extracellular solute-binding protein, family 3 YP_001158275.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158281.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001158282.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase YP_001158284.1 PFAM: protein of unknown function DUF690 YP_001158286.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001158287.1 PFAM: protein of unknown function DUF349 YP_001158289.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001158290.1 PFAM: diaminopimelate epimerase YP_001158291.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; major intrinsic protein YP_001158292.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding YP_001158293.1 PFAM: GTP-binding protein, HSR1-related YP_001158295.1 TIGRFAM: LexA repressor; PFAM: regulatory protein, MarR; peptidase S24, S26A and S26B; LexA DNA-binding domain protein YP_001158296.1 PFAM: ATP-cone domain protein YP_001158297.1 catalyzes the reduction of ribonucleotides to deoxyribonucleotides; the rate-limiting step in dNTP synthesis YP_001158300.1 PFAM: iron dependent repressor; FeoA family protein YP_001158301.1 PFAM: beta-lactamase YP_001158302.1 PFAM: beta-lactamase YP_001158303.1 PFAM: regulatory protein, LysR YP_001158304.1 PFAM: Rhodanese domain protein YP_001158305.1 PFAM: histone deacetylase superfamily YP_001158306.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein YP_001158307.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase YP_001158308.1 PFAM: regulatory protein, LuxR; transcriptional regulator TrmB YP_001158309.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein YP_001158310.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein YP_001158311.1 PFAM: D-tyrosyl-tRNA(Tyr) deacylase YP_001158312.1 PFAM: methyltransferase small YP_001158314.1 PFAM: PfkB domain protein YP_001158315.1 PFAM: Indigoidine synthase A family protein YP_001158317.1 PFAM: type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like YP_001158319.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released YP_001158320.1 PFAM: inositol monophosphatase YP_001158325.1 TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase YP_001158327.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type YP_001158329.1 PFAM: TrkA-N domain protein; TrkA-C domain protein YP_001158330.1 PFAM: TrkA-N domain protein; TrkA-C domain protein YP_001158332.1 PFAM: deoxyribonuclease/rho motif-related TRAM YP_001158333.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001158336.1 PFAM: major facilitator superfamily MFS_1 YP_001158337.1 PFAM: NADPH-dependent FMN reductase YP_001158338.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein, MerR; Redox-sensitive transcriptional activator SoxR YP_001158340.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001158341.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001158342.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001158344.1 PFAM: protein of unknown function DUF523 YP_001158345.1 PFAM: Haloacid dehalogenase domain protein hydrolase YP_001158347.1 PFAM: luciferase family protein YP_001158348.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase YP_001158349.1 PFAM: Methyltransferase type 11 YP_001158361.1 PFAM: protein of unknown function DUF397 YP_001158362.1 PFAM: helix-turn-helix domain protein YP_001158366.1 PFAM: amidohydrolase; Amidohydrolase 3 YP_001158367.1 PFAM: GCN5-related N-acetyltransferase YP_001158368.1 PFAM: ABC transporter related YP_001158370.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001158371.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001158372.1 PFAM: HRDC domain protein; 3'-5' exonuclease YP_001158373.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001158376.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001158377.1 TIGRFAM: protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase YP_001158378.1 PFAM: Chlorite dismutase YP_001158380.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001158381.1 PFAM: GCN5-related N-acetyltransferase YP_001158382.1 PFAM: cytochrome c biogenesis protein, transmembrane region YP_001158383.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001158385.1 PFAM: protein of unknown function DUF1470 YP_001158386.1 TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B YP_001158387.1 PFAM: DNA primase, small subunit YP_001158388.1 PFAM: GCN5-related N-acetyltransferase YP_001158389.1 PFAM: alpha/beta hydrolase fold; TAP domain protein YP_001158390.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth YP_001158391.1 PFAM: GCN5-related N-acetyltransferase YP_001158394.1 PFAM: protein of unknown function DUF430 YP_001158395.1 PFAM: SMC domain protein YP_001158396.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase YP_001158399.1 PFAM: bifunctional deaminase-reductase domain protein YP_001158400.1 PFAM: plasmid pRiA4b ORF-3 family protein YP_001158401.1 PFAM: extracellular solute-binding protein, family 1 YP_001158402.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158403.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158404.1 PFAM: glycoside hydrolase, family 1 YP_001158405.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001158406.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001158407.1 PFAM: aminoglycoside phosphotransferase YP_001158408.1 PFAM: GCN5-related N-acetyltransferase YP_001158410.1 PFAM: Collagen triple helix repeat YP_001158411.1 PFAM: aldehyde dehydrogenase YP_001158413.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_001158414.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001158415.1 TIGRFAM: dethiobiotin synthase YP_001158416.1 PFAM: cytochrome P450 YP_001158417.1 PFAM: Methyltransferase type 12 YP_001158418.1 PFAM: regulatory protein, TetR YP_001158419.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001158421.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001158422.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001158424.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001158425.1 PFAM: UspA domain protein YP_001158426.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase YP_001158427.1 PFAM: UspA domain protein YP_001158429.1 PFAM: regulator of chromosome condensation, RCC1 YP_001158430.1 PFAM: luciferase family protein YP_001158431.1 SMART: helix-turn-helix domain protein YP_001158432.1 PFAM: protein of unknown function DUF397 YP_001158433.1 PFAM: SpoOM family protein YP_001158438.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001158439.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001158442.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001158443.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001158444.1 PFAM: sporulation and cell division protein SsgA YP_001158450.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001158453.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001158454.1 PFAM: DsrC family protein YP_001158456.1 PFAM: OsmC family protein YP_001158459.1 TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: metallophosphoesterase YP_001158461.1 PFAM: protein of unknown function DUF664 YP_001158463.1 PFAM: Polymorphic membrane protein, Chlamydia YP_001158465.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001158467.1 PFAM: Peptidoglycan-binding domain 1 protein YP_001158468.1 PFAM: major facilitator superfamily MFS_1 YP_001158470.1 PFAM: putative esterase YP_001158471.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158472.1 PFAM: transport system permease protein YP_001158473.1 PFAM: transport system permease protein YP_001158474.1 with FepCDG is involved in the transport of ferric enterobactin YP_001158475.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase YP_001158476.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001158477.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158478.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001158479.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158480.1 PFAM: UDP-galactopyranose mutase YP_001158481.1 PFAM: glycosyl transferase, family 2 YP_001158482.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001158483.1 PFAM: aldehyde dehydrogenase YP_001158484.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001158485.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158486.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001158487.1 PFAM: protein of unknown function DUF574 YP_001158488.1 PFAM: regulatory protein, MerR YP_001158489.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter YP_001158490.1 PFAM: Carbohydrate-binding family V/XII; chitin-binding, domain 3 protein YP_001158493.1 PFAM: regulatory protein, LuxR YP_001158494.1 PFAM: Heat shock protein 70 YP_001158496.1 PFAM: GTP-binding protein, HSR1-related YP_001158497.1 PFAM: Dynamin family protein; GTP-binding protein, HSR1-related YP_001158498.1 PFAM: Rieske [2Fe-2S] domain protein YP_001158501.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase YP_001158502.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp YP_001158504.1 PFAM: helix-turn-helix domain protein YP_001158505.1 PFAM: transposase IS116/IS110/IS902 family protein YP_001158507.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001158508.1 PFAM: DSBA oxidoreductase; Na+/H+ antiporter NhaA YP_001158510.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001158511.1 PFAM: extracellular solute-binding protein, family 5 YP_001158512.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158513.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158514.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001158515.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001158516.1 PFAM: cation efflux protein YP_001158517.1 PFAM: regulatory protein, ArsR YP_001158519.1 PFAM: Amylo-alpha-1,6-glucosidase YP_001158522.1 PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001158523.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001158526.1 PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; short-chain dehydrogenase/reductase SDR; Nucleotidyl transferase; KR YP_001158527.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158528.1 PFAM: ABC-2 type transporter YP_001158529.1 PFAM: regulatory protein, TetR YP_001158530.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001158531.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001158532.1 PFAM: glycosyl transferase, group 1 YP_001158533.1 PFAM: glycosyl transferase, group 1 YP_001158534.1 PFAM: glycosyl transferase, family 2 YP_001158535.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase YP_001158537.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001158538.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001158539.1 TIGRFAM: TRAP transporter solute receptor, TAXI family YP_001158543.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001158544.1 PFAM: ATP-NAD/AcoX kinase YP_001158545.1 PFAM: peptidase M14, carboxypeptidase A YP_001158547.1 PFAM: bifunctional deaminase-reductase domain protein YP_001158548.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold YP_001158550.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001158551.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001158552.1 TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family YP_001158553.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001158554.1 TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like YP_001158555.1 PFAM: ThiJ/PfpI domain protein YP_001158556.1 PFAM: regulatory protein, TetR YP_001158560.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001158561.1 PFAM: HpcH/HpaI aldolase YP_001158562.1 PFAM: aminotransferase, class I and II YP_001158563.1 PFAM: MaoC domain protein dehydratase YP_001158566.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aminotransferase, class I and II YP_001158567.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001158568.1 PFAM: GCN5-related N-acetyltransferase YP_001158569.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001158570.1 PFAM: regulatory protein, LysR YP_001158571.1 PFAM: major facilitator superfamily MFS_1 YP_001158574.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001158575.1 PFAM: peptidase C60, sortase A and B YP_001158576.1 PFAM: sulfotransferase YP_001158577.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001158578.1 PFAM: protein of unknown function DUF75 YP_001158580.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001158583.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate YP_001158584.1 PFAM: protein phosphatase 2C domain protein YP_001158585.1 TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001158586.1 PFAM: protein of unknown function DUF397 YP_001158587.1 PFAM: helix-turn-helix domain protein YP_001158588.1 PFAM: amino acid permease-associated region YP_001158589.1 PFAM: GCN5-related N-acetyltransferase YP_001158592.1 PFAM: Conserved TM helix repeat-containing protein YP_001158595.1 PFAM: cyclase/dehydrase YP_001158598.1 PFAM: aldehyde dehydrogenase YP_001158599.1 PFAM: FAD dependent oxidoreductase YP_001158600.1 PFAM: glycosyl transferase, family 2 YP_001158601.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: glycosyl transferase, family 9; Haloacid dehalogenase domain protein hydrolase YP_001158603.1 PFAM: glycosyl transferase, group 1 YP_001158604.1 TIGRFAM: phosphoheptose isomerase; PFAM: sugar isomerase (SIS) YP_001158605.1 TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; PfkB domain protein YP_001158606.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001158607.1 PFAM: glycosyl transferase, family 9 YP_001158609.1 PFAM: glycoside hydrolase, family 3 domain protein YP_001158610.1 TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V YP_001158612.1 PFAM: MscS Mechanosensitive ion channel YP_001158613.1 PFAM: protein of unknown function DUF1469 YP_001158616.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001158618.1 PFAM: aldo/keto reductase YP_001158619.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001158620.1 catalyzes the formation of inosine from adenosine YP_001158621.1 TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001158622.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001158623.1 PFAM: ADP-ribosylation/Crystallin J1 YP_001158624.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001158625.1 PFAM: histidine triad (HIT) protein YP_001158626.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001158627.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001158628.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001158629.1 PFAM: glycosyl transferase, group 1 YP_001158631.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_001158632.1 PFAM: SNO glutamine amidotransferase; CobB/CobQ domain protein glutamine amidotransferase YP_001158633.1 PFAM: protein of unknown function DUF28 YP_001158634.1 TIGRFAM: prolyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein; YbaK/prolyl-tRNA synthetase associated region YP_001158636.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158637.1 PFAM: regulatory protein, LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001158638.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001158639.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001158640.1 PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001158641.1 PFAM: alpha/beta hydrolase fold YP_001158642.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158643.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158645.1 PFAM: inner-membrane translocator YP_001158646.1 PFAM: inner-membrane translocator YP_001158647.1 PFAM: GAF domain protein YP_001158648.1 TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR YP_001158649.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001158650.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001158651.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001158652.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein YP_001158653.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein YP_001158654.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: SecD/SecF/SecDF export membrane protein YP_001158655.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001158656.1 TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001158657.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001158658.1 PFAM: beta-lactamase domain protein YP_001158659.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001158660.1 PFAM: fatty acid desaturase, type 2 YP_001158661.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001158662.1 PFAM: regulatory protein, ArsR YP_001158663.1 PFAM: major facilitator superfamily MFS_1 YP_001158664.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001158668.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001158669.1 PFAM: Holliday junction resolvase YqgF; SMART: Resolvase, RNase H domain protein fold YP_001158670.1 PFAM: aminodeoxychorismate lyase YP_001158671.1 TIGRFAM: shikimate-5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein YP_001158673.1 PFAM: transferase hexapeptide repeat containing protein YP_001158674.1 PFAM: lipopolysaccharide biosynthesis protein YP_001158677.1 PFAM: sulfotransferase YP_001158679.1 PFAM: Oligosaccharide biosynthesis protein Alg14 like YP_001158680.1 PFAM: Glycosyltransferase 28, C-terminal domain YP_001158681.1 PFAM: glycosyl transferase, family 2 YP_001158684.1 PFAM: sodium/hydrogen exchanger YP_001158685.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001158686.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001158687.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001158688.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001158689.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001158690.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44 YP_001158691.1 PFAM: helix-turn-helix domain protein YP_001158692.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001158693.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001158694.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001158695.1 TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain YP_001158696.1 TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein YP_001158697.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001158698.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III YP_001158699.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001158701.1 SMART: guanylate kinase/L-type calcium channel region YP_001158702.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001158703.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001158704.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001158707.1 PFAM: cytochrome P450 YP_001158708.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001158709.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein YP_001158710.1 PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44 YP_001158712.1 PFAM: ribulose-phosphate 3-epimerase YP_001158713.1 PFAM: GGDEF domain containing protein; response regulator receiver YP_001158714.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001158715.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001158716.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC YP_001158717.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_001158718.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001158719.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001158720.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001158722.1 TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3 YP_001158723.1 PFAM: ribosomal protein L35 YP_001158724.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001158725.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding YP_001158726.1 TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc; aminoacyl tRNA synthetase, class II domain protein YP_001158727.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001158728.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001158729.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001158730.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001158731.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001158732.1 TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain YP_001158733.1 PFAM: arginine repressor YP_001158734.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001158735.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001158736.1 TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG) YP_001158737.1 PFAM: protein of unknown function DUF397 YP_001158740.1 PFAM: UspA domain protein YP_001158741.1 PFAM: UspA domain protein YP_001158742.1 PFAM: GCN5-related N-acetyltransferase YP_001158744.1 PFAM: thioesterase superfamily protein YP_001158745.1 TIGRFAM: tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib YP_001158746.1 PFAM: Tetratricopeptide TPR_4 YP_001158747.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001158751.1 TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein YP_001158752.1 PFAM: ATP-NAD/AcoX kinase YP_001158753.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein YP_001158754.1 PFAM: Thiamin pyrophosphokinase, catalytic region YP_001158757.1 PFAM: virulence factor MVIN family protein YP_001158758.1 PFAM: glycosyl transferase, group 1 YP_001158760.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001158761.1 PFAM: NUDIX hydrolase YP_001158762.1 PFAM: TM2 domain containing protein+B7201 YP_001158763.1 TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein YP_001158764.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001158765.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001158766.1 PFAM: chromosome segregation and condensation protein ScpA YP_001158767.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB YP_001158768.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001158769.1 TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region YP_001158770.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001158771.1 PFAM: phage integrase family protein YP_001158772.1 PFAM: Integrase, catalytic region YP_001158773.1 PFAM: transposase IS3/IS911 family protein YP_001158776.1 PFAM: phage integrase family protein YP_001158779.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001158789.1 PFAM: transposase, IS4 family protein YP_001158790.1 PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2 YP_001158794.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001158795.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; Male sterility C-terminal domain YP_001158797.1 PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein YP_001158798.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001158801.1 PFAM: periplasmic binding protein YP_001158802.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158803.1 PFAM: transport system permease protein YP_001158806.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001158807.1 PFAM: flavodoxin/nitric oxide synthase YP_001158812.1 PFAM: regulator of chromosome condensation, RCC1 YP_001158813.1 PFAM: phage integrase family protein YP_001158815.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001158819.1 PFAM: helix-turn-helix domain protein YP_001158820.1 PFAM: NUDIX hydrolase YP_001158823.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001158824.1 PFAM: NUDIX hydrolase YP_001158825.1 PFAM: PfkB domain protein YP_001158827.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001158833.1 PFAM: glycoside hydrolase, starch-binding; alpha amylase, catalytic region; alpha amylase, C-terminal all-beta; SMART: alpha amylase, catalytic sub domain YP_001158835.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158836.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001158837.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001158838.1 PFAM: extracellular solute-binding protein, family 1 YP_001158839.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001158840.1 PFAM: FAD dependent oxidoreductase YP_001158841.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001158842.1 PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001158843.1 PFAM: regulatory protein, ArsR YP_001158844.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001158846.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158849.1 PFAM: VWA containing CoxE family protein YP_001158850.1 PFAM: ATPase associated with various cellular activities, AAA_5 YP_001158857.1 PFAM: Helix-turn-helix, type 11 domain protein YP_001158858.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001158860.1 SMART: regulatory protein, MerR YP_001158863.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_001158864.1 PFAM: periplasmic solute binding protein YP_001158866.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001158867.1 PFAM: ABC-3 protein YP_001158870.1 PFAM: Class I peptide chain release factor YP_001158871.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY YP_001158874.1 PFAM: beta-lactamase YP_001158875.1 PFAM: GCN5-related N-acetyltransferase YP_001158876.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001158877.1 PFAM: short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase YP_001158878.1 PFAM: regulatory protein, ArsR YP_001158879.1 PFAM: Activator of Hsp90 ATPase 1 family protein YP_001158880.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001158883.1 PFAM: glycerophosphoryl diester phosphodiesterase; Carbohydrate binding family 6 YP_001158884.1 PFAM: ferric-uptake regulator YP_001158885.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_001158886.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001158888.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001158889.1 PFAM: transcriptional regulator domain protein; transcriptional activator domain YP_001158893.1 PFAM: ROK family protein YP_001158894.1 PFAM: acyltransferase, ChoActase/COT/CPT family YP_001158897.1 PFAM: major facilitator superfamily MFS_1 YP_001158898.1 PFAM: regulatory protein, TetR YP_001158899.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001158901.1 PFAM: major facilitator superfamily MFS_1 YP_001158902.1 PFAM: von Willebrand factor, type A YP_001158905.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001158906.1 PFAM: fatty acid desaturase YP_001158907.1 PFAM: glycosyl transferase, group 1 YP_001158908.1 PFAM: glycosyl transferase, family 2 YP_001158909.1 PFAM: glycosyl transferase, group 1 YP_001158910.1 PFAM: glycosyl transferase, family 2 YP_001158911.1 activates fatty acids by binding to coenzyme A YP_001158913.1 PFAM: protein of unknown function DUF81 YP_001158914.1 PFAM: Rhodanese domain protein YP_001158915.1 PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein YP_001158916.1 PFAM: protein of unknown function DUF156 YP_001158918.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001158919.1 PFAM: protein of unknown function DUF397 YP_001158922.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001158923.1 PFAM: metallophosphoesterase YP_001158924.1 PFAM: DNA primase, small subunit YP_001158925.1 PFAM: regulatory protein, AsnC/Lrp family YP_001158926.1 PFAM: dehydrogenase, E1 component YP_001158927.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001158928.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001158929.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein YP_001158930.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001158931.1 PFAM: DoxX family protein YP_001158933.1 PFAM: nitroreductase YP_001158935.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001158937.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; ExsB family protein YP_001158938.1 PFAM: transcription activator, effector binding; SMART: regulatory protein, MerR YP_001158939.1 PFAM: LVIVD repeat protein YP_001158940.1 PFAM: protein of unknown function DUF305 YP_001158941.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001158942.1 PFAM: glutamate--cysteine ligase, GCS2 YP_001158943.1 PFAM: protein of unknown function DUF323 YP_001158946.1 PFAM: protein of unknown function UPF0016 YP_001158947.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001158948.1 PFAM: glycosyl transferase, group 1 YP_001158951.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001158952.1 PFAM: Integral membrane protein TerC YP_001158953.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001158959.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001158960.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001158961.1 PFAM: glycosyl transferase, family 39 YP_001158962.1 PFAM: glycosyl transferase, family 2; GtrA family protein YP_001158964.1 PFAM: sulfatase YP_001158965.1 TIGRFAM: citrate synthase I; PFAM: Citrate synthase YP_001158966.1 PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001158971.1 PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001158972.1 PFAM: cytochrome c oxidase, subunit I YP_001158973.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins YP_001158974.1 PFAM: GAF domain protein; ANTAR domain protein YP_001158976.1 PFAM: transcriptional regulator domain protein YP_001158977.1 PFAM: zinc finger, DksA/TraR C4-type YP_001158980.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein YP_001158981.1 PFAM: cell divisionFtsK/SpoIIIE YP_001158985.1 PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001158988.1 PFAM: peptidase M20; peptidase dimerisation domain protein YP_001158991.1 PFAM: aldo/keto reductase YP_001158992.1 PFAM: luciferase family protein YP_001158993.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001158994.1 PFAM: Phosphoglycerate mutase YP_001158997.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001158998.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001158999.1 PFAM: protein of unknown function DUF75 YP_001159000.1 TIGRFAM: methionine synthase; PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; Vitamin B12 dependent methionine synthase, activation region; cobalamin B12-binding domain protein YP_001159001.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001159004.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159005.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159007.1 PFAM: transcriptional regulator domain protein; transcriptional activator domain YP_001159009.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001159010.1 PFAM: NDP-hexose 2,3-dehydratase YP_001159012.1 PFAM: Carboxymuconolactone decarboxylase YP_001159013.1 PFAM: glutamine amidotransferase class-I; peptidase C26 YP_001159014.1 PFAM: monooxygenase, FAD-binding YP_001159015.1 TIGRFAM: protoporphyrinogen oxidase; PFAM: amine oxidase YP_001159016.1 PFAM: ParB domain protein nuclease YP_001159017.1 PFAM: monooxygenase, FAD-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001159018.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001159019.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159020.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein YP_001159022.1 PFAM: Polyketide synthesis cyclase YP_001159023.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001159024.1 PFAM: O-methyltransferase, family 2 YP_001159025.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001159026.1 PFAM: cyclase/dehydrase YP_001159027.1 PFAM: monooxygenase, FAD-binding YP_001159028.1 PFAM: monooxygenase, FAD-binding YP_001159031.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001159033.1 PFAM: glutamine synthetase, catalytic region YP_001159034.1 PFAM: Amidase YP_001159035.1 TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase YP_001159036.1 PFAM: GCN5-related N-acetyltransferase YP_001159037.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001159038.1 PFAM: Rieske [2Fe-2S] domain protein YP_001159039.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159040.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159041.1 PFAM: alpha/beta hydrolase fold; TAP domain protein YP_001159042.1 PFAM: glycosyl transferase, family 28; protein of unknown function DUF1205 YP_001159043.1 PFAM: O-methyltransferase, family 2; Methyltransferase type 12 YP_001159045.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001159046.1 PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001159047.1 PFAM: Semialdehyde dehydrogenase, NAD - binding; oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001159049.1 PFAM: protein of unknown function DUF1205 YP_001159050.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001159051.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001159052.1 PFAM: beta-ketoacyl synthase YP_001159053.1 PFAM: beta-ketoacyl synthase YP_001159054.1 PFAM: phosphopantetheine-binding YP_001159055.1 PFAM: acyl transferase domain protein YP_001159057.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001159058.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase YP_001159059.1 PFAM: major facilitator superfamily MFS_1 YP_001159060.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001159061.1 PFAM: protein of unknown function DUF214 YP_001159062.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159063.1 PFAM: regulatory protein, LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001159065.1 PFAM: CBS domain containing protein; peptidase M50 YP_001159069.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001159070.1 PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein YP_001159071.1 PFAM: protein of unknown function DUF797 YP_001159072.1 PFAM: 20S proteasome, A and B subunits YP_001159073.1 PFAM: 20S proteasome, A and B subunits YP_001159074.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001159075.1 PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein YP_001159080.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001159081.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase YP_001159082.1 PFAM: diacylglycerol kinase, catalytic region YP_001159083.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001159084.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DSH domain protein; SMART: DEAD-like helicases-like YP_001159085.1 PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001159086.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159087.1 PFAM: regulatory protein, AsnC/Lrp family YP_001159088.1 PFAM: Phosphoglycerate mutase YP_001159090.1 PFAM: Radical SAM domain protein YP_001159092.1 PFAM: Amidohydrolase 3 YP_001159094.1 PFAM: cobalamin B12-binding domain protein YP_001159097.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001159098.1 PFAM: glycosyl transferase, family 2 YP_001159099.1 PFAM: FxsA cytoplasmic membrane protein YP_001159102.1 PFAM: protein of unknown function DUF6, transmembrane YP_001159103.1 PFAM: regulatory protein, AsnC/Lrp family; regulatory protein, ArsR YP_001159104.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase YP_001159105.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001159106.1 PFAM: GCN5-related N-acetyltransferase YP_001159107.1 PFAM: bifunctional deaminase-reductase domain protein YP_001159109.1 PFAM: regulatory protein, TetR YP_001159112.1 PFAM: aminoglycoside phosphotransferase YP_001159113.1 PFAM: glycoside hydrolase, family 5; cellulose-binding, family II YP_001159114.1 PFAM: Cupin 2, conserved barrel domain protein YP_001159115.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001159116.1 PFAM: regulatory protein, TetR YP_001159117.1 PFAM: major facilitator superfamily MFS_1 YP_001159118.1 PFAM: cytochrome P450 YP_001159120.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001159121.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein YP_001159123.1 TIGRFAM: integral membrane protein MviN; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein YP_001159124.1 PFAM: Erythromycin esterase YP_001159125.1 PFAM: regulatory protein, MerR YP_001159126.1 PFAM: peptidase M48, Ste24p YP_001159127.1 PFAM: GCN5-related N-acetyltransferase YP_001159128.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001159129.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001159130.1 PFAM: regulatory protein, ArsR YP_001159131.1 PFAM: major facilitator superfamily MFS_1 YP_001159135.1 PFAM: major facilitator superfamily MFS_1 YP_001159136.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001159137.1 SMART: helix-turn-helix domain protein YP_001159139.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001159140.1 PFAM: DGPFAETKE family protein YP_001159142.1 PFAM: regulatory protein, MerR; protein phosphatase 2C domain protein YP_001159151.1 PFAM: DoxX family protein YP_001159152.1 PFAM: aminoglycoside phosphotransferase YP_001159153.1 PFAM: protein phosphatase 2C domain protein YP_001159154.1 PFAM: UbiC transcription regulator-associated domain protein YP_001159155.1 PFAM: aminotransferase, class I and II YP_001159156.1 PFAM: helix-turn-helix domain protein YP_001159157.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR YP_001159158.1 PFAM: regulatory protein, TetR YP_001159159.1 PFAM: major intrinsic protein YP_001159160.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001159161.1 PFAM: ABC transporter related YP_001159162.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159164.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II YP_001159165.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I YP_001159166.1 PFAM: phospholipid/glycerol acyltransferase YP_001159167.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001159169.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001159170.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001159171.1 PFAM: 3-dehydroquinate synthase YP_001159172.1 PFAM: luciferase family protein YP_001159173.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001159175.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_001159176.1 PFAM: major facilitator superfamily MFS_1 YP_001159177.1 PFAM: regulatory protein, MarR YP_001159178.1 PFAM: GCN5-related N-acetyltransferase; NADPH-dependent FMN reductase YP_001159180.1 PFAM: regulatory protein, TetR YP_001159182.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001159183.1 TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_001159185.1 PFAM: GCN5-related N-acetyltransferase YP_001159186.1 PFAM: regulatory protein, TetR YP_001159187.1 PFAM: major facilitator superfamily MFS_1 YP_001159190.1 PFAM: GCN5-related N-acetyltransferase YP_001159193.1 PFAM: cytochrome P450 YP_001159196.1 PFAM: 4-oxalocrotonate tautomerase YP_001159197.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159198.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001159199.1 SMART: helix-turn-helix domain protein YP_001159200.1 PFAM: Anthranilate synthase component I and chorismate binding protein YP_001159202.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001159203.1 PFAM: Silent information regulator protein Sir2 YP_001159204.1 SMART: regulatory protein, MerR YP_001159205.1 PFAM: protein of unknown function DUF151 YP_001159206.1 PFAM: regulatory protein, MerR YP_001159207.1 PFAM: Forkhead-associated protein YP_001159208.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein YP_001159209.1 PFAM: protein of unknown function DUF881 YP_001159210.1 PFAM: protein of unknown function DUF1290 YP_001159211.1 PFAM: protein of unknown function DUF881 YP_001159212.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001159213.1 PFAM: UspA domain protein YP_001159216.1 TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase YP_001159218.1 PFAM: major facilitator superfamily MFS_1 YP_001159219.1 PFAM: Alkaline phosphatase YP_001159221.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159222.1 PFAM: FAD dependent oxidoreductase YP_001159223.1 PFAM: protein of unknown function DUF101 YP_001159224.1 PFAM: protein of unknown function UPF0027 YP_001159226.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001159227.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001159228.1 PFAM: extracellular solute-binding protein, family 1 YP_001159229.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001159231.1 PFAM: pentapeptide repeat protein YP_001159233.1 PFAM: Lycopene beta and epsilon cyclase YP_001159234.1 PFAM: major facilitator superfamily MFS_1 YP_001159235.1 PFAM: band 7 protein YP_001159236.1 PFAM: AMP-dependent synthetase and ligase YP_001159237.1 PFAM: protein of unknown function DUF1622 YP_001159238.1 PFAM: Ion transport protein; Ion transport 2 domain protein YP_001159239.1 PFAM: regulatory protein, MarR YP_001159241.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001159244.1 PFAM: regulatory protein, MerR YP_001159245.1 PFAM: major facilitator superfamily MFS_1 YP_001159251.1 PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001159253.1 PFAM: protein of unknown function DUF181 YP_001159254.1 PFAM: ABC-2 type transporter YP_001159255.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159256.1 PFAM: peptidase M50 YP_001159258.1 PFAM: Lantibiotic dehydratase domain protein YP_001159260.1 PFAM: protein of unknown function DUF181 YP_001159262.1 PFAM: transcriptional regulator domain protein; transcriptional activator domain YP_001159263.1 PFAM: regulatory protein, LuxR YP_001159265.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein YP_001159266.1 PFAM: major facilitator superfamily MFS_1 YP_001159267.1 PFAM: PilT protein domain protein YP_001159268.1 TIGRFAM: prevent-host-death family protein YP_001159269.1 PFAM: glycoside hydrolase, family 3 domain protein; Na-Ca exchanger/integrin-beta4 YP_001159270.1 PFAM: NUDIX hydrolase YP_001159271.1 TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001159272.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001159273.1 PFAM: protein of unknown function DUF397 YP_001159274.1 SMART: helix-turn-helix domain protein YP_001159278.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001159279.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001159280.1 PFAM: Carbohydrate-binding family V/XII; chitin-binding, domain 3 protein YP_001159281.1 PFAM: protein of unknown function DUF305 YP_001159282.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001159283.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001159284.1 PFAM: Abortive infection protein YP_001159285.1 PFAM: extracellular solute-binding protein, family 5 YP_001159286.1 PFAM: extracellular solute-binding protein, family 5 YP_001159287.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001159288.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 YP_001159289.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001159293.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001159294.1 TIGRFAM: methyltransferase FkbM family YP_001159295.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001159296.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001159298.1 molecular chaperone YP_001159299.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 YP_001159301.1 PFAM: aminotransferase, class I and II YP_001159302.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase YP_001159303.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001159304.1 PFAM: cytochrome P450 YP_001159305.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001159306.1 PFAM: AMP-dependent synthetase and ligase YP_001159307.1 PFAM: major facilitator superfamily MFS_1 YP_001159308.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001159309.1 PFAM: protein of unknown function DUF407 YP_001159310.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001159311.1 PFAM: dehydrogenase, E1 component YP_001159313.1 PFAM: Phytanoyl-CoA dioxygenase YP_001159314.1 TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159315.1 PFAM: beta-ketoacyl synthase YP_001159316.1 PFAM: AMP-dependent synthetase and ligase YP_001159318.1 PFAM: beta-ketoacyl synthase YP_001159320.1 PFAM: 4'-phosphopantetheinyl transferase YP_001159321.1 PFAM: AMP-dependent synthetase and ligase YP_001159322.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001159323.1 PFAM: beta-ketoacyl synthase YP_001159324.1 PFAM: beta-ketoacyl synthase YP_001159325.1 PFAM: Cupin 2, conserved barrel domain protein YP_001159326.1 PFAM: cyclase/dehydrase YP_001159327.1 PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001159328.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein YP_001159329.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; PFAM: carboxyl transferase; acetyl-CoA carboxylase, alpha subunit YP_001159330.1 PFAM: Polyketide synthesis cyclase YP_001159331.1 PFAM: transcriptional activator domain YP_001159332.1 PFAM: Polyketide synthesis cyclase YP_001159333.1 PFAM: monooxygenase, FAD-binding YP_001159335.1 PFAM: Polymorphic membrane protein, Chlamydia YP_001159337.1 PFAM: regulatory protein, LuxR; Tetratricopeptide TPR_4 YP_001159338.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase YP_001159339.1 PFAM: Camphor resistance CrcB protein YP_001159340.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein YP_001159341.1 PFAM: Precorrin-8X methylmutase CbiC/CobH YP_001159342.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001159343.1 TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein YP_001159344.1 TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001159345.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_001159346.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001159347.1 TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001159348.1 TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase YP_001159349.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001159350.1 PFAM: von Willebrand factor, type A; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001159351.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_001159354.1 proposed role in polysaccahride synthesis YP_001159355.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001159356.1 PFAM: major facilitator superfamily MFS_1 YP_001159357.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001159359.1 PFAM: major facilitator superfamily MFS_1 YP_001159362.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159363.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase YP_001159364.1 PFAM: glutamate--cysteine ligase, GCS2 YP_001159365.1 PFAM: ferric-uptake regulator YP_001159366.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein, MerR; TOBE domain protein YP_001159367.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001159368.1 TIGRFAM: NifC-like ABC-type porter; molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001159369.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001159370.1 PFAM: IucA/IucC family protein YP_001159373.1 PFAM: Pyridoxal-dependent decarboxylase YP_001159374.1 PFAM: periplasmic binding protein YP_001159375.1 PFAM: transport system permease protein YP_001159376.1 PFAM: transport system permease protein YP_001159377.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159378.1 PFAM: peptidase S45, penicillin amidase YP_001159380.1 PFAM: bifunctional deaminase-reductase domain protein YP_001159381.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001159384.1 PFAM: glycosyl transferase, group 1 YP_001159387.1 PFAM: CDP-alcohol phosphatidyltransferase; sulfatase YP_001159388.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein YP_001159391.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001159392.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001159394.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001159395.1 PFAM: transport-associated YP_001159398.1 PFAM: FAD dependent oxidoreductase YP_001159399.1 PFAM: FAD linked oxidase domain protein YP_001159402.1 PFAM: flavoprotein YP_001159403.1 PFAM: regulatory protein, TetR YP_001159404.1 PFAM: Bile acid:sodium symporter YP_001159407.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159408.1 PFAM: aminotransferase, class I and II YP_001159409.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001159411.1 PFAM: protein of unknown function DUF461 YP_001159412.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase YP_001159413.1 PFAM: copper resistance protein CopC YP_001159414.1 TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001159415.1 TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein YP_001159416.1 periplasmic cobalt binding component of the cobalt transport system YP_001159417.1 catalyzes the ATP-dependent transport of cobalt YP_001159418.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001159419.1 PFAM: Radical SAM domain protein YP_001159420.1 PFAM: transcriptional regulator PadR family protein YP_001159421.1 PFAM: luciferase family protein YP_001159422.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001159423.1 PFAM: regulatory protein, TetR YP_001159424.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159425.1 PFAM: aldehyde dehydrogenase YP_001159426.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001159427.1 PFAM: coenzyme A transferase YP_001159428.1 PFAM: coenzyme A transferase YP_001159429.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001159430.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001159431.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001159432.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159434.1 PFAM: cytochrome P450 YP_001159435.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001159436.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001159437.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001159438.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001159439.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001159440.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159441.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159442.1 TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold YP_001159445.1 PFAM: protein of unknown function DUF35 YP_001159446.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001159447.1 PFAM: regulatory protein, TetR YP_001159450.1 PFAM: thioesterase superfamily protein YP_001159451.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione YP_001159452.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001159453.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159454.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001159455.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001159456.1 PFAM: luciferase family protein YP_001159458.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001159460.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001159461.1 activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence YP_001159462.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001159463.1 activates fatty acids by binding to coenzyme A YP_001159464.1 PFAM: protein of unknown function DUF35 YP_001159466.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001159467.1 PFAM: Saccharopine dehydrogenase; homoserine dehydrogenase, NAD-binding YP_001159468.1 PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001159469.1 PFAM: condensation domain protein; phosphopantetheine-binding YP_001159470.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001159471.1 PFAM: Methyltransferase type 12 YP_001159472.1 PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase YP_001159473.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001159474.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001159475.1 PFAM: extracellular solute-binding protein, family 5 YP_001159476.1 PFAM: beta-ketoacyl synthase; Thioesterase; acyl transferase domain protein; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Non-ribosomal peptide synthetase; KR YP_001159477.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Non-ribosomal peptide synthetase YP_001159478.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001159479.1 PFAM: monooxygenase, FAD-binding YP_001159480.1 PFAM: multicopper oxidase, type 2 YP_001159482.1 PFAM: AMP-dependent synthetase and ligase YP_001159484.1 PFAM: protein of unknown function DUF664 YP_001159490.1 PFAM: flavin reductase domain protein, FMN-binding YP_001159491.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159492.1 PFAM: alpha/beta hydrolase fold YP_001159493.1 PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159494.1 PFAM: Rieske [2Fe-2S] domain protein YP_001159496.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001159497.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001159498.1 initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione YP_001159499.1 PFAM: MaoC domain protein dehydratase YP_001159500.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001159501.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159503.1 PFAM: regulatory protein, ArsR YP_001159504.1 PFAM: Activator of Hsp90 ATPase 1 family protein YP_001159505.1 PFAM: bifunctional deaminase-reductase domain protein YP_001159506.1 PFAM: glycoside hydrolase, family 5; cellulose-binding, family II; Fibronectin, type III domain protein YP_001159508.1 PFAM: glycoside hydrolase, starch-binding; alpha amylase, catalytic region; alpha amylase, C-terminal all-beta; SMART: alpha amylase, catalytic sub domain YP_001159509.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159510.1 SMART: helix-turn-helix- domain containing protein, AraC type YP_001159511.1 PFAM: protein of unknown function DUF985 YP_001159512.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159514.1 PFAM: regulatory protein, MerR YP_001159515.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001159516.1 PFAM: cytochrome P450 YP_001159517.1 PFAM: flavin reductase domain protein, FMN-binding YP_001159519.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KR YP_001159521.1 PFAM: ASPIC/UnbV domain protein; FG-GAP repeat protein YP_001159522.1 PFAM: protein of unknown function DUF1702 YP_001159523.1 PFAM: protein of unknown function DUF1702 YP_001159524.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; Male sterility C-terminal domain YP_001159525.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001159526.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase YP_001159528.1 PFAM: Wyosine base formation YP_001159530.1 PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159532.1 PFAM: monooxygenase, FAD-binding YP_001159533.1 PFAM: alpha/beta hydrolase fold; Epoxide hydrolase domain protein YP_001159534.1 PFAM: luciferase family protein YP_001159535.1 PFAM: 4-hydroxyphenylacetate 3-hydroxylase YP_001159536.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001159537.1 PFAM: DGPFAETKE family protein YP_001159540.1 PFAM: major facilitator superfamily MFS_1 YP_001159541.1 PFAM: DGPFAETKE family protein YP_001159542.1 PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159543.1 PFAM: condensation domain protein YP_001159545.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001159546.1 PFAM: cytochrome P450 YP_001159547.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding YP_001159548.1 PFAM: MbtH domain protein YP_001159549.1 TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159553.1 PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein YP_001159555.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001159557.1 PFAM: major facilitator superfamily MFS_1 YP_001159558.1 PFAM: protein of unknown function DUF899, thioredoxin family protein YP_001159559.1 PFAM: transcriptional regulator domain protein; transcriptional activator domain; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein YP_001159560.1 PFAM: peptidase M16 domain protein YP_001159562.1 PFAM: Radical SAM domain protein YP_001159563.1 PFAM: Hemerythrin HHE cation binding domain protein YP_001159564.1 PFAM: zinc finger, SWIM domain protein YP_001159574.1 PFAM: major facilitator superfamily MFS_1 YP_001159575.1 PFAM: regulatory protein, ArsR YP_001159577.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001159578.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001159579.1 PFAM: protein of unknown function DUF214 YP_001159580.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159581.1 PFAM: regulatory protein, LuxR YP_001159583.1 PFAM: Thioesterase YP_001159584.1 PFAM: carboxyl transferase YP_001159585.1 PFAM: major facilitator superfamily MFS_1 YP_001159586.1 PFAM: regulatory protein, TetR YP_001159588.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001159590.1 PFAM: cytochrome P450 YP_001159592.1 PFAM: aminotransferase, class I and II YP_001159594.1 PFAM: AMP-dependent synthetase and ligase YP_001159595.1 PFAM: AMP-dependent synthetase and ligase YP_001159597.1 TIGRFAM: proline-specific peptidase; PFAM: alpha/beta hydrolase fold YP_001159598.1 PFAM: beta-ketoacyl synthase; Thioesterase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001159599.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001159600.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001159601.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001159603.1 PFAM: conserved hypothetical protein CHP02464 YP_001159605.1 PFAM: cytochrome P450 YP_001159606.1 PFAM: AMP-dependent synthetase and ligase YP_001159607.1 PFAM: class II aldolase/adducin family protein YP_001159608.1 PFAM: DSBA oxidoreductase YP_001159610.1 PFAM: alpha/beta hydrolase fold YP_001159611.1 PFAM: beta-ketoacyl synthase YP_001159612.1 PFAM: beta-ketoacyl synthase YP_001159613.1 PFAM: beta-ketoacyl synthase YP_001159614.1 PFAM: beta-ketoacyl synthase YP_001159615.1 PFAM: phosphopantetheine-binding YP_001159616.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001159617.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001159618.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001159619.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001159620.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001159622.1 PFAM: AMP-dependent synthetase and ligase YP_001159623.1 PFAM: FAD dependent oxidoreductase YP_001159624.1 PFAM: phosphopantetheine-binding YP_001159625.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; Non-ribosomal peptide synthetase YP_001159627.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001159629.1 PFAM: FAD dependent oxidoreductase YP_001159630.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159632.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001159633.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159634.1 PFAM: O-methyltransferase, family 2 YP_001159635.1 PFAM: AMP-dependent synthetase and ligase YP_001159636.1 PFAM: Thioesterase YP_001159637.1 TIGRFAM: thiazolinyl imide reductase; PFAM: oxidoreductase domain protein YP_001159638.1 PFAM: Saccharopine dehydrogenase YP_001159639.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; Methyltransferase type 11; Methyltransferase type 12; Non-ribosomal peptide synthetase YP_001159640.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Non-ribosomal peptide synthetase YP_001159641.1 PFAM: 4'-phosphopantetheinyl transferase YP_001159642.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001159643.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159644.1 PFAM: cytochrome P450 YP_001159645.1 PFAM: condensation domain protein YP_001159648.1 PFAM: cytochrome P450 YP_001159649.1 PFAM: O-methyltransferase, family 2 YP_001159651.1 PFAM: condensation domain protein YP_001159652.1 PFAM: luciferase family protein YP_001159653.1 PFAM: NADPH-dependent FMN reductase YP_001159654.1 PFAM: phosphopantetheine-binding YP_001159655.1 PFAM: O-methyltransferase, family 2; Methyltransferase type 11; Methyltransferase type 12 YP_001159656.1 PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001159657.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001159658.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001159659.1 PFAM: aldehyde dehydrogenase YP_001159660.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001159661.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001159668.1 PFAM: luciferase family protein YP_001159670.1 PFAM: permease YP_001159672.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001159673.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001159674.1 PFAM: ribosomal protein L28 YP_001159675.1 PFAM: cobalamin synthesis CobW domain protein YP_001159676.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001159677.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001159678.1 PFAM: ferric-uptake regulator YP_001159679.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001159686.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001159688.1 PFAM: Silent information regulator protein Sir2; thiamine pyrophosphate enzyme, central region YP_001159691.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001159693.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001159694.1 PFAM: Cupin 2, conserved barrel domain protein YP_001159698.1 PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor, type A YP_001159700.1 PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001159701.1 PFAM: WGR domain protein YP_001159702.1 PFAM: acyltransferase 3 YP_001159703.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001159704.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001159710.1 PFAM: regulatory protein, TetR YP_001159713.1 PFAM: Ankyrin YP_001159714.1 TIGRFAM: polymorphic outer membrane protein YP_001159717.1 PFAM: GCN5-related N-acetyltransferase YP_001159720.1 PFAM: alpha/beta hydrolase fold YP_001159724.1 PFAM: phage integrase family protein YP_001159725.1 PFAM: Recombinase YP_001159726.1 PFAM: Fibronectin, type III domain protein; Tetratricopeptide TPR_4 YP_001159727.1 PFAM: Fibronectin, type III domain protein YP_001159728.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001159729.1 PFAM: protein of unknown function DUF58 YP_001159730.1 PFAM: transglutaminase domain protein YP_001159731.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159732.1 PFAM: luciferase family protein YP_001159733.1 PFAM: protein of unknown function DUF1028 YP_001159735.1 PFAM: phosphoesterase, PA-phosphatase related YP_001159736.1 PFAM: MMPL domain protein YP_001159737.1 PFAM: major facilitator superfamily MFS_1 YP_001159738.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001159742.1 PFAM: major facilitator superfamily MFS_1 YP_001159743.1 PFAM: protein of unknown function DUF328 YP_001159744.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001159746.1 PFAM: sulfatase YP_001159749.1 PFAM: GCN5-related N-acetyltransferase YP_001159752.1 PFAM: protein of unknown function DUF323 YP_001159753.1 PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001159756.1 activates fatty acids by binding to coenzyme A YP_001159757.1 PFAM: transposase, IS4 family protein YP_001159758.1 PFAM: Ricin B lectin; peptidase S1 and S6, chymotrypsin/Hap YP_001159760.1 PFAM: regulatory protein, TetR YP_001159762.1 PFAM: Integral membrane protein TerC YP_001159765.1 PFAM: regulatory protein, ArsR YP_001159767.1 PFAM: glycoside hydrolase, family 9; Carbohydrate-binding, CenC domain protein domain protein; glycoside hydrolase, family 9 domain protein Ig domain protein YP_001159770.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001159771.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; peptidase, alpha-lytic pro domain YP_001159773.1 PFAM: glycoside hydrolase, family 48; PKD domain containing protein; cellulose-binding, family II YP_001159774.1 PFAM: glycoside hydrolase, family 1 YP_001159775.1 PFAM: carbohydrate kinase, FGGY YP_001159776.1 PFAM: glutamine amidotransferase class-I; Anthranilate synthase component I and chorismate binding protein YP_001159777.1 PFAM: glycosyl transferase, family 2 YP_001159778.1 PFAM: major facilitator superfamily MFS_1 YP_001159780.1 PFAM: major facilitator superfamily MFS_1 YP_001159781.1 PFAM: glycoside hydrolase, family 18; cellulose-binding, family II; SMART: chitinase II YP_001159783.1 PFAM: regulatory protein, TetR YP_001159784.1 PFAM: major facilitator superfamily MFS_1 YP_001159786.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001159787.1 PFAM: major facilitator superfamily MFS_1 YP_001159788.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001159789.1 PFAM: alpha/beta hydrolase fold YP_001159792.1 PFAM: Haloacid dehalogenase domain protein hydrolase YP_001159793.1 PFAM: membrane-bound metal-dependent hydrolase YP_001159794.1 PFAM: amidohydrolase 2 YP_001159796.1 PFAM: DNA-directed DNA polymerase YP_001159797.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001159798.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001159799.1 PFAM: extracellular solute-binding protein, family 1 YP_001159800.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS) YP_001159802.1 TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) YP_001159803.1 PFAM: MMPL domain protein YP_001159804.1 PFAM: regulatory protein, TetR YP_001159807.1 PFAM: acyltransferase 3 YP_001159808.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001159809.1 PFAM: aminotransferase class-III YP_001159810.1 PFAM: helix-turn-helix, HxlR type; transcriptional regulator PadR family protein YP_001159811.1 PFAM: Endoribonuclease L-PSP YP_001159812.1 PFAM: ribosomal RNA adenine methylase transferase; Methyltransferase type 11; Methyltransferase type 12 YP_001159813.1 PFAM: NmrA family protein YP_001159814.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001159815.1 PFAM: regulatory protein, MerR; PBS lyase HEAT domain protein repeat-containing protein YP_001159817.1 PFAM: Asparaginase/glutaminase YP_001159818.1 PFAM: NmrA family protein YP_001159819.1 PFAM: cyclase family protein YP_001159820.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001159822.1 PFAM: purine catabolism PurC domain protein YP_001159823.1 PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001159824.1 PFAM: protein of unknown function DUF397 YP_001159826.1 PFAM: Polymorphic membrane protein, Chlamydia YP_001159829.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001159830.1 PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001159831.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001159833.1 PFAM: band 7 protein YP_001159834.1 PFAM: protein of unknown function DUF107 YP_001159837.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001159838.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001159839.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001159840.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159841.1 PFAM: von Willebrand factor, type A YP_001159842.1 PFAM: protein of unknown function DUF58 YP_001159843.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001159845.1 PFAM: membrane-flanked domain YP_001159846.1 PFAM: membrane-flanked domain YP_001159847.1 PFAM: phosphoesterase, PA-phosphatase related YP_001159848.1 PFAM: thioesterase superfamily protein YP_001159849.1 PFAM: beta-lactamase domain protein YP_001159850.1 PFAM: regulatory protein, MarR YP_001159851.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001159852.1 PFAM: cellulose-binding, family II; chitin-binding, domain 3 protein YP_001159854.1 PFAM: sigma-70 region 2 domain protein YP_001159855.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001159856.1 PFAM: Tetratricopeptide TPR_4; SMART: Tetratricopeptide domain protein YP_001159857.1 PFAM: NADPH-dependent FMN reductase YP_001159860.1 PFAM: Lantibiotic dehydratase domain protein YP_001159861.1 PFAM: Lantibiotic dehydratase domain protein YP_001159863.1 PFAM: Lantibiotic dehydratase domain protein YP_001159864.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001159866.1 PFAM: FAD dependent oxidoreductase YP_001159868.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001159869.1 PFAM: Lantibiotic dehydratase domain protein YP_001159870.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; methyltransferase small; Methyltransferase type 11; Methyltransferase type 12 YP_001159871.1 TIGRFAM: thioester reductase domain; PFAM: GCN5-related N-acetyltransferase; beta-ketoacyl synthase; AMP-dependent synthetase and ligase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; phosphopantetheine-binding; Male sterility C-terminal domain YP_001159872.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase YP_001159873.1 PFAM: peptidase M24; peptidase M24B, X-Pro dipeptidase/aminopeptidase domain protein YP_001159876.1 TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region YP_001159877.1 TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein YP_001159879.1 PFAM: protein of unknown function RIO1 YP_001159880.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001159881.1 PFAM: regulatory protein, TetR YP_001159883.1 PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel YP_001159885.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001159886.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001159887.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001159889.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159891.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001159892.1 PFAM: protein of unknown function DUF59 YP_001159893.1 TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein YP_001159894.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase, class V YP_001159895.1 TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase YP_001159896.1 PFAM: Rieske [2Fe-2S] domain protein YP_001159897.1 TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein YP_001159898.1 TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein YP_001159899.1 PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein YP_001159900.1 PFAM: cytochrome oxidase assembly YP_001159903.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001159904.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001159905.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate YP_001159906.1 PFAM: phosphoglucose isomerase (PGI) YP_001159907.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001159909.1 TIGRFAM: 6-phosphogluconolactonase; PFAM: glucosamine/galactosamine-6-phosphate isomerase YP_001159910.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit YP_001159911.1 PFAM: triosephosphate isomerase YP_001159912.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001159913.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001159914.1 PFAM: protein of unknown function DUF199 YP_001159915.1 PFAM: protein of unknown function UPF0052 and CofD YP_001159916.1 PFAM: uncharacterised P-loop ATPase protein UPF0042 YP_001159917.1 PFAM: helix-turn-helix domain protein YP_001159919.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001159920.1 PFAM: PilT protein domain protein YP_001159921.1 TIGRFAM: prevent-host-death family protein YP_001159922.1 PFAM: alpha/beta hydrolase fold YP_001159923.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001159924.1 PFAM: Rieske [2Fe-2S] domain protein YP_001159925.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001159926.1 PFAM: GTPase EngC YP_001159927.1 in Corynebacterium glutamicum this enzyme catalyzes the conversion of maleylpyruvate into fumarylpyruvate in a glutathione-independent gentisate pathway; dependent on mycothiol YP_001159928.1 PFAM: beta-lactamase domain protein YP_001159930.1 PFAM: protein of unknown function DUF312 YP_001159932.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001159933.1 PFAM: FAD linked oxidase domain protein YP_001159935.1 PFAM: methyltransferase small YP_001159936.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001159937.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap YP_001159939.1 PFAM: peptidase S15; X-Pro dipeptidyl-peptidase C-terminal domain protein YP_001159940.1 PFAM: regulatory protein, MarR YP_001159941.1 PFAM: MMPL domain protein YP_001159942.1 PFAM: Lytic transglycosylase, catalytic YP_001159944.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001159945.1 PFAM: beta-lactamase YP_001159947.1 PFAM: Integral membrane protein TerC YP_001159948.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001159949.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001159951.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain YP_001159952.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001159953.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001159954.1 PFAM: bifunctional deaminase-reductase domain protein YP_001159955.1 SMART: helix-turn-helix- domain containing protein, AraC type YP_001159957.1 TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; SMART: 3'-5' exonuclease; Helix-hairpin-helix domain protein, class 2 YP_001159958.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159959.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159960.1 PFAM: inner-membrane translocator YP_001159961.1 PFAM: inner-membrane translocator YP_001159962.1 PFAM: Extracellular ligand-binding receptor YP_001159963.1 PFAM: response regulator receiver; ANTAR domain protein YP_001159964.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_001159966.1 PFAM: regulatory protein, AsnC/Lrp family YP_001159967.1 PFAM: protein of unknown function DUF81 YP_001159968.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001159970.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001159971.1 PFAM: acyl-CoA thioesterase YP_001159972.1 PFAM: pyruvate kinase YP_001159973.1 PFAM: lipase, class 2 YP_001159974.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159975.1 PFAM: ABC-2 type transporter YP_001159976.1 PFAM: helix-turn-helix domain protein YP_001159978.1 TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001159979.1 PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase YP_001159980.1 PFAM: monooxygenase, FAD-binding YP_001159981.1 PFAM: prolipoprotein diacylglyceryl transferase YP_001159982.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001159983.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001159984.1 PFAM: Indole-3-glycerol phosphate synthase YP_001159987.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001159988.1 PFAM: phosphoribosyl-AMP cyclohydrolase YP_001159989.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001159990.1 TIGRFAM: ABC drug efflux pump, inner membrane subunit, DrrB family; PFAM: ABC-2 type transporter YP_001159991.1 PFAM: regulatory protein, TetR YP_001159992.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001159993.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001159996.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001159997.1 PFAM: protein of unknown function DUF161 YP_001159999.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001160000.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein YP_001160001.1 PFAM: regulatory protein, MarR YP_001160002.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis YP_001160004.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001160006.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001160007.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001160008.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001160009.1 PFAM: peptidase S16, lon domain protein YP_001160013.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001160014.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001160015.1 PFAM: zinc finger, DksA/TraR C4-type YP_001160016.1 PFAM: protein of unknown function DUF167 YP_001160018.1 PFAM: DivIVA family protein YP_001160020.1 PFAM: protein of unknown function DUF552 YP_001160021.1 PFAM: alanine racemase domain protein YP_001160022.1 TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase; Tubulin/FtsZ domain protein YP_001160023.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type YP_001160024.1 TIGRFAM: UDP-N-acetylmuramate--alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001160025.1 TIGRFAM: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: glycosyl transferase, family 28; Glycosyltransferase 28, C-terminal domain YP_001160026.1 PFAM: cell cycle protein YP_001160027.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001160028.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001160029.1 TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001160030.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001160032.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase YP_001160033.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001160034.1 PFAM: Mur ligase, middle domain protein; domain of unknown function DUF1727 YP_001160035.1 PFAM: CobB/CobQ domain protein glutamine amidotransferase YP_001160037.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001160039.1 PFAM: multiple resistance and pH regulation protein F YP_001160040.1 PFAM: cation antiporter YP_001160041.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001160042.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001160043.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein YP_001160044.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001160045.1 PFAM: protein of unknown function DUF58 YP_001160046.1 PFAM: transglutaminase domain protein YP_001160048.1 PFAM: UMUC domain protein DNA-repair protein YP_001160049.1 PFAM: type I phosphodiesterase/nucleotide pyrophosphatase YP_001160050.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001160051.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. YP_001160055.1 PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001160057.1 PFAM: GCN5-related N-acetyltransferase YP_001160058.1 PFAM: protein of unknown function DUF422 YP_001160059.1 PFAM: glycosyl transferase, family 2 YP_001160060.1 TIGRFAM: Phytoene dehydrogenase-related protein; PFAM: amine oxidase; FAD dependent oxidoreductase YP_001160061.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001160062.1 TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_001160063.1 PFAM: Polyprenyl synthetase YP_001160065.1 PFAM: protein kinase; PASTA domain containing protein; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001160066.1 TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2 YP_001160067.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001160068.1 TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II YP_001160070.1 PFAM: glycoside hydrolase, family 18; cellulose-binding, family II; SMART: chitinase II YP_001160071.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001160072.1 PFAM: PfkB domain protein YP_001160073.1 PFAM: N-acylglucosamine 2-epimerase YP_001160074.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160075.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160076.1 PFAM: extracellular solute-binding protein, family 1 YP_001160077.1 TIGRFAM: putative alpha-1,2-mannosidase; PFAM: coagulation factor 5/8 type domain protein; glycosyl hydrolase 92 YP_001160078.1 TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001160079.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001160081.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp YP_001160083.1 PFAM: glycosyl transferase, family 20 YP_001160085.1 PFAM: flavin-containing monooxygenase FMO YP_001160086.1 TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein YP_001160088.1 PFAM: cyclase/dehydrase YP_001160089.1 PFAM: AMP-dependent synthetase and ligase YP_001160090.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001160091.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001160092.1 PFAM: protein of unknown function DUF574; Methyltransferase type 12 YP_001160093.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001160094.1 PFAM: glycosyl transferase, group 1 YP_001160095.1 PFAM: peptidase M48, Ste24p YP_001160098.1 contains 3'-5'exonuclease domain YP_001160099.1 PFAM: TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001160100.1 PFAM: NUDIX hydrolase YP_001160101.1 PFAM: Nucleotidyl transferase YP_001160102.1 PFAM: regulatory protein, AsnC/Lrp family YP_001160104.1 PFAM: Cytochrome b/b6, N-terminal domain YP_001160105.1 PFAM: Rieske [2Fe-2S] domain protein YP_001160106.1 PFAM: cytochrome c, class I YP_001160107.1 PFAM: cytochrome c oxidase, subunit III YP_001160110.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001160112.1 PFAM: cytochrome c oxidase, subunit II YP_001160113.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001160114.1 PFAM: SirA family protein YP_001160115.1 PFAM: PfkB domain protein YP_001160116.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein YP_001160117.1 PFAM: glycerate kinase YP_001160118.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001160119.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001160121.1 PFAM: Tetratricopeptide TPR_2 repeat protein YP_001160122.1 PFAM: aldo/keto reductase YP_001160123.1 PFAM: peptidase M50 YP_001160125.1 PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; cobalbumin biosynthesis enzyme YP_001160126.1 PFAM: cobalamin-5-phosphate synthase CobS YP_001160128.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001160129.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein YP_001160131.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001160132.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001160133.1 PFAM: protein of unknown function DUF893, YccS/YhfK YP_001160134.1 PFAM: regulatory protein, MerR YP_001160135.1 PFAM: aldo/keto reductase YP_001160136.1 PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731 YP_001160138.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001160140.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001160143.1 PFAM: RDD domain containing protein YP_001160144.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_001160147.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001160148.1 PFAM: glutamine amidotransferase class-I YP_001160149.1 PFAM: peptidase U61, LD-carboxypeptidase A YP_001160151.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_001160152.1 TIGRFAM: NAD+ synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; NAD+ synthase; ExsB family protein YP_001160153.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001160155.1 TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent YP_001160156.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001160157.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160158.1 PFAM: regulatory protein, TetR; Tetracyclin repressor domain protein YP_001160159.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001160161.1 PFAM: transposase IS3/IS911 family protein YP_001160162.1 PFAM: Integrase, catalytic region YP_001160165.1 PFAM: protein of unknown function DUF81 YP_001160166.1 PFAM: ribonuclease H; Phosphoglycerate mutase YP_001160167.1 PFAM: protein of unknown function DUF164 YP_001160168.1 PFAM: protein of unknown function DUF34 YP_001160170.1 PFAM: helix-turn-helix domain protein YP_001160173.1 PFAM: zinc finger, SWIM domain protein YP_001160174.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like YP_001160175.1 PFAM: polysaccharide pyruvyl transferase YP_001160176.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein YP_001160177.1 PFAM: polysaccharide deacetylase YP_001160178.1 PFAM: protein of unknown function DUF1211 YP_001160179.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001160181.1 PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein YP_001160182.1 PFAM: regulatory protein, MarR YP_001160183.1 PFAM: protein of unknown function UPF0047 YP_001160184.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001160185.1 PFAM: cyclase/dehydrase YP_001160186.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001160189.1 PFAM: acyl transferase domain protein YP_001160190.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001160191.1 carries the fatty acid chain in fatty acid biosynthesis YP_001160192.1 PFAM: beta-ketoacyl synthase YP_001160193.1 PFAM: carboxyl transferase YP_001160195.1 PFAM: glycoside hydrolase, family 3 domain protein YP_001160198.1 PFAM: alpha/beta hydrolase fold YP_001160200.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001160202.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001160203.1 PFAM: DSBA oxidoreductase YP_001160204.1 PFAM: regulatory protein, LuxR YP_001160205.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001160206.1 PFAM: Saccharopine dehydrogenase YP_001160207.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001160208.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001160209.1 TIGRFAM: polymorphic outer membrane protein YP_001160210.1 PFAM: CBS domain containing protein; peptidase M50 YP_001160213.1 PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001160214.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001160215.1 PFAM: aldo/keto reductase YP_001160216.1 SMART: Parallel beta-helix repeat YP_001160218.1 TIGRFAM: polymorphic outer membrane protein YP_001160219.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160220.1 PFAM: regulatory protein, ArsR YP_001160221.1 PFAM: Amidase YP_001160227.1 PFAM: amine oxidase YP_001160228.1 PFAM: MMPL domain protein YP_001160230.1 PFAM: ABC-2 type transporter YP_001160231.1 PFAM: ABC-2 type transporter YP_001160232.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160234.1 TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase DnaG, DnaB-binding; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_001160235.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter YP_001160236.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein YP_001160237.1 TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001160238.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001160239.1 PFAM: glycoside hydrolase, family 20 YP_001160241.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS YP_001160242.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001160244.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001160246.1 PFAM: periplasmic solute binding protein YP_001160247.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160248.1 PFAM: ABC-3 protein YP_001160249.1 PFAM: regulatory protein, ArsR YP_001160250.1 PFAM: alpha/beta hydrolase fold YP_001160252.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160253.1 PFAM: cobalt transport protein YP_001160254.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001160255.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001160256.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO YP_001160257.1 PFAM: acyltransferase 3 YP_001160258.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001160260.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001160261.1 PFAM: protein of unknown function UPF0054 YP_001160262.1 PFAM: PhoH family protein; KH, type 1, domain protein YP_001160263.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001160264.1 TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein YP_001160265.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001160267.1 TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001160268.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001160271.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001160273.1 PFAM: aminoglycoside phosphotransferase YP_001160274.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001160276.1 TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_001160277.1 PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein YP_001160278.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1 YP_001160279.1 TIGRFAM: degV family protein; PFAM: DegV family protein YP_001160281.1 PFAM: Phosphoglycerate mutase YP_001160282.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein YP_001160283.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001160284.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase YP_001160285.1 PFAM: protein of unknown function DUF397 YP_001160288.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001160289.1 involved in the peptidyltransferase reaction during translation YP_001160290.1 PFAM: ribosomal protein L21 YP_001160291.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein YP_001160293.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001160295.1 PFAM: phospholipid/glycerol acyltransferase YP_001160296.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_001160297.1 PFAM: Alkaline phosphatase YP_001160298.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001160299.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160301.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001160302.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001160305.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001160306.1 binds and unfolds substrates as part of the ClpXP protease YP_001160307.1 PFAM: peptidase S14, ClpP YP_001160308.1 PFAM: peptidase S14, ClpP YP_001160309.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001160311.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_001160313.1 PFAM: transposase, IS4 family protein YP_001160315.1 PFAM: regulatory protein, MerR; transcription activator, effector binding YP_001160316.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001160318.1 PFAM: regulatory protein, ArsR YP_001160321.1 PFAM: GCN5-related N-acetyltransferase YP_001160323.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001160326.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase YP_001160329.1 PFAM: Amidase YP_001160330.1 PFAM: amidohydrolase 2 YP_001160331.1 catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde in the final enzymatic step of quinolinate biosynthesis YP_001160332.1 PFAM: Endoribonuclease L-PSP YP_001160333.1 PFAM: Hydratase/decarboxylase YP_001160334.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001160335.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001160336.1 PFAM: Hydratase/decarboxylase YP_001160337.1 PFAM: aldehyde dehydrogenase YP_001160338.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001160339.1 TIGRFAM: kynureninase; PFAM: aminotransferase, class V YP_001160340.1 PFAM: tryptophan 2,3-dioxygenase YP_001160341.1 PFAM: regulatory protein, AsnC/Lrp family YP_001160343.1 PFAM: peptidase C60, sortase A and B YP_001160344.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001160345.1 PFAM: MscS Mechanosensitive ion channel YP_001160346.1 PFAM: major facilitator superfamily MFS_1 YP_001160347.1 PFAM: globin YP_001160350.1 PFAM: thioesterase superfamily protein YP_001160351.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001160352.1 PFAM: glycosyl transferase, family 20 YP_001160353.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: trehalose-phosphatase; glycoside hydrolase 15-related YP_001160354.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001160355.1 PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase YP_001160356.1 PFAM: aminotransferase, class I and II YP_001160357.1 PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001160360.1 PFAM: peptidase M20; peptidase dimerisation domain protein YP_001160362.1 SMART: Rhodanese domain protein YP_001160363.1 TIGRFAM: cobyric acid synthase CobQ; PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase YP_001160364.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001160365.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n YP_001160370.1 PFAM: bifunctional deaminase-reductase domain protein YP_001160371.1 PFAM: phospholipid/glycerol acyltransferase YP_001160372.1 PFAM: Amylo-alpha-1,6-glucosidase YP_001160374.1 PFAM: CBS domain containing protein YP_001160375.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001160376.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001160377.1 PFAM: peptidase M16 domain protein YP_001160378.1 PFAM: peptidase M16 domain protein YP_001160380.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001160383.1 PFAM: protein of unknown function DUF1360 YP_001160388.1 PFAM: NLP/P60 protein YP_001160389.1 PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2 YP_001160390.1 PFAM: thymidylate kinase YP_001160393.1 PFAM: metallophosphoesterase YP_001160395.1 PFAM: TspO/MBR family protein YP_001160396.1 PFAM: extracellular solute-binding protein, family 1 YP_001160397.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160398.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160399.1 PFAM: major facilitator superfamily MFS_1 YP_001160400.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY YP_001160401.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001160402.1 PFAM: sugar transferase YP_001160403.1 PFAM: von Willebrand factor, type A YP_001160405.1 PFAM: protein of unknown function, ATP binding YP_001160406.1 PFAM: protein of unknown function DUF742 YP_001160407.1 PFAM: Roadblock/LC7 family protein YP_001160408.1 PFAM: ATP-binding region, ATPase domain protein domain protein; Nitrate and nitrite sensing domain protein YP_001160411.1 PFAM: glycoside hydrolase, family 6; cellulose-binding, family II YP_001160413.1 PFAM: peptidase C60, sortase A and B YP_001160414.1 PFAM: NAD-glutamate dehydrogenase YP_001160415.1 PFAM: Arginase/agmatinase/formiminoglutamase YP_001160416.1 PFAM: Thioredoxin domain YP_001160417.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase YP_001160418.1 TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase YP_001160419.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001160420.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160421.1 TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001160424.1 PFAM: protein of unknown function UPF0118 YP_001160427.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001160428.1 PFAM: aldehyde dehydrogenase YP_001160429.1 PFAM: protein of unknown function DUF91 YP_001160430.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein YP_001160431.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160432.1 PFAM: ABC-2 type transporter YP_001160433.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001160434.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001160435.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase YP_001160437.1 PFAM: H+-transporting two-sector ATPase, delta/epsilon subunit YP_001160438.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator YP_001160439.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001160440.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001160441.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001160442.1 TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+-transporting two-sector ATPase, delta (OSCP) subunit YP_001160443.1 TIGRFAM: ATP synthase F0, B subunit; PFAM: H+-transporting two-sector ATPase, B/B' subunit YP_001160444.1 TIGRFAM: ATP synthase F0, C subunit; PFAM: H+-transporting two-sector ATPase, C subunit YP_001160445.1 TIGRFAM: ATP synthase F0, A subunit; PFAM: H+-transporting two-sector ATPase, A subunit YP_001160448.1 PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001160449.1 PFAM: low molecular weight phosphotyrosine protein phosphatase YP_001160450.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001160451.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small YP_001160452.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001160453.1 TIGRFAM: peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein YP_001160454.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001160455.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001160456.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001160457.1 PFAM: major facilitator superfamily MFS_1 YP_001160458.1 PFAM: acriflavin resistance protein YP_001160459.1 TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001160460.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001160461.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001160462.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001160464.1 PFAM: protein of unknown function DUF305 YP_001160466.1 PFAM: protein of unknown function DUF397 YP_001160469.1 TIGRFAM: YD repeat protein YP_001160471.1 PFAM: polysaccharide deacetylase YP_001160472.1 PFAM: DNA primase, small subunit YP_001160473.1 PFAM: regulatory protein, TetR YP_001160474.1 PFAM: MMPL domain protein YP_001160475.1 PFAM: Erythromycin esterase YP_001160478.1 PFAM: ribosomal RNA adenine methylase transferase YP_001160479.1 PFAM: oxidoreductase domain protein YP_001160482.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001160483.1 PFAM: glycoside hydrolase, family 16; Carbohydrate binding family 6; SMART: cellulose binding, type IV YP_001160484.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_001160485.1 PFAM: amidinotransferase YP_001160486.1 TIGRFAM: ornithine aminotransferase; PFAM: aminotransferase class-III YP_001160488.1 PFAM: fatty acid desaturase YP_001160489.1 PFAM: CutA1 divalent ion tolerance protein YP_001160490.1 PFAM: phospholipid/glycerol acyltransferase YP_001160491.1 PFAM: Patatin YP_001160492.1 PFAM: glycosyl transferase, group 1 YP_001160493.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001160494.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001160495.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001160497.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160499.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth YP_001160501.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001160502.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase YP_001160503.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001160504.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding YP_001160505.1 PFAM: peptidase S24, S26A and S26B YP_001160509.1 PFAM: diacylglycerol kinase, catalytic region YP_001160510.1 PFAM: transcription factor WhiB YP_001160511.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein YP_001160512.1 PFAM: phosphoadenosine phosphosulfate reductase YP_001160513.1 PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001160515.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation/phosphoacceptor; PAS fold-4 domain protein YP_001160516.1 PFAM: sugar isomerase (SIS) YP_001160517.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001160518.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001160519.1 PFAM: regulatory protein, TetR YP_001160520.1 PFAM: GCN5-related N-acetyltransferase YP_001160521.1 PFAM: biotin/lipoyl attachment domain-containing protein YP_001160523.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001160525.1 PFAM: transcription factor WhiB YP_001160526.1 PFAM: protein of unknown function DUF159 YP_001160527.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001160528.1 PFAM: GTPase EngC YP_001160529.1 TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase YP_001160531.1 PFAM: glycosyl transferase, group 1 YP_001160533.1 PFAM: ATP-binding region, ATPase domain protein domain protein YP_001160534.1 TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_001160535.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001160537.1 PFAM: bifunctional deaminase-reductase domain protein YP_001160538.1 PFAM: protein of unknown function UPF0182 YP_001160542.1 PFAM: protein of unknown function DUF45 YP_001160545.1 PFAM: ABC-1 domain protein YP_001160546.1 PFAM: HMG-I and HMG-Y, DNA-binding domain protein; transcription factor WhiB YP_001160548.1 PFAM: UvrD/REP helicase; HRDC domain protein YP_001160549.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; glutaredoxin 2 YP_001160550.1 PFAM: major facilitator superfamily MFS_1 YP_001160551.1 SMART: helix-turn-helix domain protein YP_001160552.1 PFAM: protein of unknown function DUF397 YP_001160554.1 PFAM: NUDIX hydrolase YP_001160555.1 PFAM: peptidase M16 domain protein YP_001160556.1 PFAM: peptidase M16 domain protein YP_001160557.1 PFAM: UvrD/REP helicase YP_001160558.1 PFAM: UvrD/REP helicase YP_001160559.1 PFAM: conserved hypothetical protein 730 YP_001160560.1 PFAM: conserved hypothetical protein 730 YP_001160561.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate YP_001160563.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001160565.1 PFAM: protein of unknown function DUF541 YP_001160566.1 PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase, NAD-binding YP_001160567.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis YP_001160568.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001160569.1 PFAM: GCN5-related N-acetyltransferase YP_001160572.1 PFAM: LmbE family protein YP_001160573.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein YP_001160574.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001160575.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001160577.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001160578.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source YP_001160579.1 PFAM: NUDIX hydrolase YP_001160582.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001160583.1 PFAM: helix-turn-helix domain protein YP_001160585.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001160586.1 PFAM: Endonuclease V YP_001160587.1 PFAM: peptidase S45, penicillin amidase YP_001160588.1 PFAM: GCN5-related N-acetyltransferase YP_001160589.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418 YP_001160590.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001160591.1 PFAM: peptidase S51, dipeptidase E YP_001160592.1 PFAM: helix-turn-helix- domain containing protein, AraC type; HhH-GPD family protein; Ada, metal-binding domain protein; AlkA domain protein YP_001160593.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001160594.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001160595.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001160597.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160599.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160601.1 PFAM: adenylylsulfate kinase YP_001160602.1 Converts isocitrate to alpha ketoglutarate YP_001160603.1 PFAM: Lactate/malate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001160604.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001160605.1 PFAM: extracellular solute-binding protein, family 5 YP_001160606.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160607.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160608.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001160609.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001160612.1 PFAM: alpha/beta hydrolase fold YP_001160613.1 PFAM: regulatory protein, ArsR YP_001160614.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001160615.1 involved in de novo purine biosynthesis YP_001160616.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001160621.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001160622.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001160623.1 PFAM: cobalamin B12-binding domain protein YP_001160624.1 PFAM: peptidase M23B YP_001160625.1 PFAM: peptidase M23B YP_001160626.1 TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase YP_001160627.1 TIGRFAM: chorismate mutase; PFAM: Chorismate mutase YP_001160628.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001160629.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001160630.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160631.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160632.1 PFAM: extracellular solute-binding protein, family 5 YP_001160633.1 PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein; Sigma-70, region 4 type 2 YP_001160634.1 PFAM: ATP-binding region, ATPase domain protein domain protein; PspC domain protein YP_001160635.1 PFAM: PspC domain protein YP_001160637.1 TIGRFAM: phosphatidylserine decarboxylase related protein; PFAM: phosphatidylserine decarboxylase-related YP_001160638.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001160639.1 PFAM: NUDIX hydrolase YP_001160640.1 PFAM: NUDIX hydrolase YP_001160641.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001160642.1 PFAM: FAD dependent oxidoreductase YP_001160643.1 PFAM: peptidase M1, membrane alanine aminopeptidase YP_001160644.1 TIGRFAM: IMP dehydrogenase family protein YP_001160645.1 TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase YP_001160647.1 PFAM: regulatory protein, LuxR YP_001160648.1 PFAM: oxidoreductase, molybdopterin binding; Mo-co oxidoreductase dimerisation domain YP_001160649.1 TIGRFAM: chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1 YP_001160650.1 PFAM: chaperonin Cpn10 YP_001160652.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001160655.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160656.1 PFAM: inner-membrane translocator YP_001160657.1 PFAM: ROK family protein YP_001160659.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001160660.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase YP_001160661.1 PFAM: peptidase M22, glycoprotease YP_001160662.1 TIGRFAM: uracil-DNA glycosylase; PFAM: Uracil-DNA glycosylase superfamily YP_001160663.1 PFAM: protein of unknown function UPF0079 YP_001160664.1 PFAM: alpha/beta hydrolase fold YP_001160665.1 TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_001160666.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein YP_001160667.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001160668.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001160669.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II YP_001160670.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001160671.1 forms a direct contact with the tRNA during translation YP_001160672.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001160673.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1 YP_001160675.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001160676.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein YP_001160677.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein YP_001160678.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001160679.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane YP_001160680.1 PFAM: protein of unknown function, ATP binding YP_001160681.1 PFAM: protein of unknown function DUF742 YP_001160682.1 PFAM: Roadblock/LC7 family protein YP_001160683.1 PFAM: ATP-binding region, ATPase domain protein domain protein; Nitrate and nitrite sensing domain protein YP_001160684.1 PFAM: Extracellular ligand-binding receptor YP_001160685.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001160686.1 PFAM: membrane lipoprotein lipid attachment site YP_001160687.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160688.1 PFAM: luciferase family protein YP_001160691.1 PFAM: thiamine biosynthesis protein ThiC YP_001160692.1 TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1 YP_001160693.1 PFAM: thiamine monophosphate synthase YP_001160694.1 PFAM: thiazole biosynthesis family protein YP_001160695.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein YP_001160696.1 TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase YP_001160697.1 TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase YP_001160698.1 PFAM: aldo/keto reductase YP_001160699.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160700.1 PFAM: methyltransferase small YP_001160701.1 PFAM: tRNA pseudouridine synthase YP_001160702.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001160703.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001160704.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001160705.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001160706.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001160707.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001160708.1 TIGRFAM: translation initiation factor IF-1; PFAM: RNA binding S1 domain protein; S1, IF1 family protein YP_001160709.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001160710.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001160711.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001160712.1 late assembly protein YP_001160713.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001160714.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001160715.1 TIGRFAM: ribosomal protein L18; PFAM: ribosomal protein L18P/L5E YP_001160716.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001160717.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001160718.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_001160719.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001160720.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001160721.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001160722.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001160723.1 one of the stabilizing components for the large ribosomal subunit YP_001160724.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001160725.1 TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3-C-terminal domain protein; KH, type 2 domain protein; Ribosomal protein S3, N-terminal domain; SMART: KH domain protein YP_001160726.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001160727.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001160728.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001160729.1 PFAM: Ribosomal protein L25/L23 YP_001160730.1 PFAM: ribosomal protein L4/L1e YP_001160731.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001160732.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001160733.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001160734.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001160735.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001160736.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001160739.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160740.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001160741.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001160742.1 TIGRFAM: ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12-like YP_001160743.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001160744.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001160745.1 binds directly to 23S ribosomal RNA YP_001160746.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_001160747.1 TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein YP_001160748.1 PFAM: MaoC domain protein dehydratase YP_001160750.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_001160751.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein YP_001160753.1 PFAM: major facilitator superfamily MFS_1 YP_001160754.1 PFAM: protein of unknown function DUF191 YP_001160755.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001160758.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001160759.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001160761.1 PFAM: regulatory protein GntR, HTH; Helix-turn-helix, type 11 domain protein YP_001160766.1 PFAM: peptidase M48, Ste24p YP_001160767.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160768.1 PFAM: regulatory protein GntR, HTH; Helix-turn-helix, type 11 domain protein YP_001160772.1 PFAM: regulatory protein, TetR YP_001160775.1 PFAM: DNA primase, small subunit YP_001160776.1 PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase YP_001160777.1 PFAM: Ku domain protein YP_001160778.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001160780.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001160781.1 activates fatty acids by binding to coenzyme A YP_001160782.1 PFAM: NUDIX hydrolase YP_001160783.1 TIGRFAM: cytidyltransferase-related domain; rfaE bifunctional protein; PFAM: cytidylyltransferase; PfkB domain protein YP_001160784.1 PFAM: glycosyl transferase, family 2 YP_001160785.1 PFAM: glycosyl transferase, family 9 YP_001160786.1 PFAM: heat shock protein Hsp20 YP_001160788.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001160789.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001160790.1 TIGRFAM: polymorphic outer membrane protein YP_001160791.1 PFAM: OsmC family protein YP_001160792.1 PFAM: beta-lactamase YP_001160793.1 PFAM: protein of unknown function DUF81 YP_001160796.1 PFAM: GCN5-related N-acetyltransferase YP_001160803.1 PFAM: regulatory protein, TetR YP_001160804.1 PFAM: alpha/beta hydrolase fold YP_001160805.1 PFAM: alpha/beta hydrolase fold YP_001160816.1 PFAM: RecT protein YP_001160821.1 PFAM: BRO domain protein domain protein YP_001160823.1 SMART: helix-turn-helix domain protein YP_001160824.1 PFAM: phage integrase family protein YP_001160826.1 PFAM: PSP1 domain protein YP_001160830.1 TIGRFAM: DNA polymerase III, delta prime subunit; SMART: AAA ATPase YP_001160831.1 PFAM: thymidylate kinase; major facilitator superfamily MFS_1 YP_001160833.1 PFAM: regulatory protein, TetR YP_001160834.1 TIGRFAM: FAD-linked oxidoreductase; PFAM: FAD linked oxidase domain protein; D-arabinono-1,4-lactone oxidase YP_001160835.1 TIGRFAM: DNA topoisomerase I; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein YP_001160838.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001160840.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001160841.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001160845.1 PFAM: type II secretion system protein YP_001160847.1 PFAM: type II secretion system protein E YP_001160849.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490 YP_001160851.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001160852.1 PFAM: alpha/beta hydrolase fold YP_001160857.1 PFAM: protein of unknown function DUF839 YP_001160858.1 PFAM: regulatory protein, IclR YP_001160859.1 PFAM: Polyprenyl synthetase YP_001160860.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160861.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001160862.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001160863.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160864.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160865.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160866.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160867.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160868.1 TIGRFAM: NADH-quinone oxidoreductase, F subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001160869.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160870.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160871.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160872.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001160873.1 Catalyzes the transfer of electrons from NADH to quinone YP_001160874.1 TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase YP_001160875.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12 YP_001160876.1 PFAM: Radical SAM domain protein YP_001160877.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001160878.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59 YP_001160879.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein YP_001160880.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001160881.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001160884.1 PFAM: protein of unknown function DUF178 YP_001160886.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160887.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160888.1 PFAM: transport system permease protein; ABC-3 protein YP_001160889.1 PFAM: periplasmic binding protein YP_001160890.1 PFAM: peptidase M14, carboxypeptidase A YP_001160893.1 PFAM: Radical SAM domain protein YP_001160894.1 PFAM: NLP/P60 protein YP_001160896.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001160897.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001160898.1 PFAM: regulatory protein, AsnC/Lrp family YP_001160899.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: regulatory protein, MerR YP_001160900.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein YP_001160901.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001160902.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein YP_001160903.1 PFAM: cytochrome c assembly protein YP_001160904.1 PFAM: ResB family protein YP_001160905.1 PFAM: cytochrome c biogenesis protein, transmembrane region YP_001160906.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001160907.1 PFAM: Phosphoglycerate mutase YP_001160908.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001160909.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001160910.1 PFAM: response regulator receiver YP_001160911.1 PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001160912.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001160913.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller YP_001160914.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001160915.1 PFAM: major facilitator superfamily MFS_1 YP_001160916.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001160919.1 PFAM: protein phosphatase 2C domain protein; Stage II sporulation E family protein YP_001160920.1 PFAM: major facilitator superfamily MFS_1 YP_001160921.1 PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein YP_001160922.1 PFAM: PEBP family protein YP_001160923.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001160926.1 PFAM: formylmethionine deformylase; helix-turn-helix domain protein YP_001160927.1 PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001160928.1 PFAM: Abortive infection protein YP_001160929.1 SMART: helix-turn-helix domain protein YP_001160937.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160938.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001160939.1 PFAM: regulatory protein, LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001160941.1 PFAM: transposase Tn3 family protein YP_001160942.1 PFAM: protein of unknown function UPF0074; regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001160943.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001160944.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein YP_001160945.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001160946.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001160947.1 PFAM: transposase, IS4 family protein YP_001160950.1 PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region YP_001160951.1 PFAM: AMP-dependent synthetase and ligase YP_001160952.1 PFAM: DNA polymerase, beta domain protein region YP_001160954.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001160955.1 SMART: nucleoside diphosphate kinase YP_001160959.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001160960.1 PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001160964.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis YP_001160965.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001160966.1 PFAM: histone family protein DNA-binding protein YP_001160967.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001160968.1 PFAM: cobalamin synthesis CobW domain protein YP_001160972.1 PFAM: major facilitator superfamily MFS_1 YP_001160974.1 PFAM: response regulator receiver YP_001160976.1 TIGRFAM: conserved hypothetical integral membrane protein YP_001160978.1 PFAM: cobalt transport protein YP_001160979.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160982.1 PFAM: PfkB domain protein YP_001160986.1 PFAM: transposase, IS4 family protein YP_001160989.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001160990.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001160991.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001160992.1 PFAM: protein of unknown function DUF214 YP_001160995.1 PFAM: alpha/beta hydrolase fold YP_001160996.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase YP_001160998.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001160999.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein YP_001161000.1 PFAM: GTPase EngC YP_001161001.1 PFAM: cobalamin synthesis CobW domain protein YP_001161002.1 PFAM: protein of unknown function DUF574 YP_001161007.1 PFAM: GCN5-related N-acetyltransferase YP_001161008.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001161010.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001161012.1 PFAM: peptidase C60, sortase A and B YP_001161013.1 PFAM: BioY protein YP_001161016.1 PFAM: ADP-ribosylation/Crystallin J1 YP_001161018.1 PFAM: MOSC domain containing protein YP_001161019.1 PFAM: GCN5-related N-acetyltransferase YP_001161021.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001161022.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region YP_001161023.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001161024.1 PFAM: DGPFAETKE family protein YP_001161026.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001161027.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding YP_001161028.1 TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia YP_001161029.1 SMART: regulatory protein, IclR YP_001161030.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001161031.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001161032.1 PFAM: protein of unknown function DUF6, transmembrane YP_001161033.1 PFAM: protein of unknown function DUF1470 YP_001161034.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein YP_001161036.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001161038.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001161039.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001161040.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001161041.1 PFAM: protein of unknown function DUF397 YP_001161042.1 PFAM: helix-turn-helix domain protein YP_001161044.1 PFAM: bifunctional deaminase-reductase domain protein YP_001161045.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001161046.1 PFAM: Endoribonuclease L-PSP YP_001161048.1 PFAM: Allergen V5/Tpx-1 family protein YP_001161049.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001161050.1 PFAM: TPR repeat-containing protein; transcriptional regulator domain protein; NB-ARC domain protein; transcriptional activator domain; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001161051.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region YP_001161053.1 PFAM: major facilitator superfamily MFS_1 YP_001161054.1 PFAM: regulatory protein, ArsR YP_001161055.1 PFAM: regulatory protein, AsnC/Lrp family YP_001161056.1 TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001161057.1 PFAM: RDD domain containing protein YP_001161058.1 TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II YP_001161059.1 SMART: Pyrrolo-quinoline quinone YP_001161061.1 PFAM: protein of unknown function DUF397 YP_001161062.1 TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase YP_001161064.1 PFAM: homogentisate 1,2-dioxygenase; Cupin 2, conserved barrel domain protein YP_001161065.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001161066.1 TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase YP_001161067.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_001161068.1 PFAM: transcription factor CarD YP_001161070.1 PFAM: chalcone and stilbene synthase domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein YP_001161071.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001161072.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001161073.1 PFAM: UbiA prenyltransferase YP_001161075.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001161076.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair YP_001161078.1 PFAM: formylmethionine deformylase YP_001161079.1 PFAM: amino acid-binding ACT domain protein YP_001161080.1 PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001161081.1 PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001161083.1 TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type YP_001161084.1 TIGRFAM: putative transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor YP_001161085.1 TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001161086.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001161088.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001161089.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001161091.1 PFAM: protein of unknown function DUF185 YP_001161092.1 PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa YP_001161094.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001161095.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001161096.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001161097.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001161099.1 PFAM: inner-membrane translocator YP_001161101.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001161102.1 TIGRFAM: dihydroneopterin aldolase YP_001161103.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001161108.1 PFAM: peptidase M23B YP_001161111.1 PFAM: cell divisionFtsK/SpoIIIE YP_001161113.1 PFAM: GTP cyclohydrolase I YP_001161114.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; SMART: AAA ATPase YP_001161115.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001161116.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein YP_001161118.1 TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_001161119.1 PFAM: Inorganic pyrophosphatase YP_001161120.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001161121.1 PFAM: phosphoesterase, PA-phosphatase related YP_001161122.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; Colicin V production protein YP_001161123.1 PFAM: NUDIX hydrolase YP_001161124.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001161125.1 TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001161127.1 PFAM: protein of unknown function DUF105 YP_001161128.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001161129.1 PFAM: regulatory protein, TetR YP_001161130.1 PFAM: Wyosine base formation YP_001161131.1 PFAM: protein of unknown function DUF1446 YP_001161132.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001161133.1 PFAM: carboxyl transferase YP_001161134.1 PFAM: biotin/lipoyl attachment domain-containing protein; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; D-alanine--D-alanine ligase domain protein YP_001161135.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001161137.1 PFAM: regulatory protein GntR, HTH YP_001161139.1 PFAM: ROK family protein YP_001161140.1 PFAM: uncharacterised conserved protein UCP012702; MlrC domain protein YP_001161141.1 PFAM: ROK family protein YP_001161142.1 PFAM: extracellular solute-binding protein, family 5 YP_001161143.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001161144.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001161145.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001161146.1 PFAM: CutC family protein YP_001161149.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001161150.1 PFAM: protein of unknown function RIO1; protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001161152.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein YP_001161153.1 PFAM: beta-lactamase domain protein YP_001161154.1 PFAM: Endoribonuclease L-PSP YP_001161157.1 PFAM: Anion-transporting ATPase YP_001161159.1 PFAM: transcription factor WhiB YP_001161160.1 PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001161161.1 PFAM: GatB/Yqey domain protein YP_001161162.1 PFAM: metallophosphoesterase YP_001161163.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001161164.1 PFAM: regulatory protein, TetR YP_001161168.1 PFAM: regulatory protein, TetR; Tetracyclin repressor domain protein YP_001161175.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001161176.1 PFAM: NUDIX hydrolase YP_001161177.1 PFAM: purine or other phosphorylase, family 1 YP_001161179.1 PFAM: dienelactone hydrolase YP_001161180.1 TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase YP_001161181.1 PFAM: amino acid permease-associated region YP_001161182.1 PFAM: pentapeptide repeat protein YP_001161184.1 PFAM: protein of unknown function DUF397 YP_001161186.1 PFAM: protein of unknown function DUF1023 YP_001161188.1 PFAM: regulatory protein, MerR YP_001161189.1 PFAM: ABC-2 type transporter YP_001161190.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001161191.1 PFAM: MmgE/PrpD family protein YP_001161193.1 PFAM: ribonucleotide reductase YP_001161194.1 TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit; PFAM: ribonucleotide reductase large subunit; ATP-cone domain protein; Ribonucleotide reductase large subunit, N terminal domain protein YP_001161195.1 PFAM: alpha/beta hydrolase fold YP_001161196.1 PFAM: inositol monophosphatase YP_001161197.1 PFAM: polysaccharide deacetylase YP_001161198.1 PFAM: GCN5-related N-acetyltransferase YP_001161199.1 PFAM: beta-lactamase YP_001161203.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_001161205.1 PFAM: cobalt transport protein YP_001161206.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001161208.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001161209.1 PFAM: DGPFAETKE family protein YP_001161210.1 PFAM: peptidase S45, penicillin amidase YP_001161211.1 PFAM: glycoside hydrolase, family 19; Carbohydrate-binding family V/XII YP_001161212.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001161215.1 PFAM: fumarate lyase YP_001161216.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001161218.1 PFAM: coagulation factor 5/8 type domain protein YP_001161220.1 PFAM: O-methyltransferase, family 2; Methyltransferase type 12 YP_001161221.1 PFAM: major facilitator superfamily MFS_1 YP_001161222.1 TIGRFAM: amino acid adenylation domain; thioester reductase domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; 3-beta hydroxysteroid dehydrogenase/isomerase; phosphopantetheine-binding; Male sterility C-terminal domain YP_001161223.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding YP_001161225.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001161226.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding YP_001161227.1 PFAM: MbtH domain protein YP_001161229.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001161230.1 PFAM: Ricin B lectin; glycoside hydrolase, family 5; glycoside hydrolase, family 12 YP_001161231.1 PFAM: alpha/beta hydrolase fold YP_001161232.1 PFAM: helix-turn-helix domain protein YP_001161233.1 PFAM: cytochrome P450 YP_001161236.1 TIGRFAM: polymorphic outer membrane protein YP_001161237.1 PFAM: regulatory protein, DeoR YP_001161238.1 PFAM: major facilitator superfamily MFS_1 YP_001161239.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001161243.1 PFAM: regulatory protein, MerR YP_001161244.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_001161245.1 TIGRFAM: Phytoene dehydrogenase-related protein; PFAM: amine oxidase; FAD dependent oxidoreductase YP_001161246.1 PFAM: Polyprenyl synthetase YP_001161247.1 PFAM: Squalene/phytoene synthase YP_001161248.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_001161249.1 PFAM: MmgE/PrpD family protein YP_001161250.1 PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase YP_001161251.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001161253.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001161254.1 TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase YP_001161255.1 PFAM: Peptidoglycan-binding LysM YP_001161257.1 PFAM: MOSC domain containing protein YP_001161258.1 PFAM: TadE family protein YP_001161259.1 PFAM: TadE family protein YP_001161261.1 PFAM: type II secretion system protein YP_001161262.1 PFAM: type II secretion system protein YP_001161263.1 PFAM: type II secretion system protein E YP_001161265.1 PFAM: SAF domain YP_001161268.1 PFAM: peptidase A24A, prepilin type IV YP_001161269.1 PFAM: protein of unknown function DUF397 YP_001161272.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001161273.1 SMART: helix-turn-helix- domain containing protein, AraC type YP_001161276.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001161277.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein, MerR; Redox-sensitive transcriptional activator SoxR YP_001161278.1 PFAM: Transketolase domain protein YP_001161279.1 PFAM: Transketolase, central region YP_001161280.1 PFAM: glycosyl transferase, family 2 YP_001161282.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001161283.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001161285.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001161287.1 PFAM: Rhomboid family protein YP_001161288.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001161290.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA family protein YP_001161291.1 PFAM: aminotransferase, class I and II YP_001161292.1 PFAM: CBS domain containing protein YP_001161293.1 PFAM: Nucleotidyl transferase YP_001161294.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase YP_001161295.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001161296.1 PFAM: glycosyl transferase, group 1 YP_001161297.1 PFAM: Formamidopyrimidine-DNA glycolase YP_001161298.1 PFAM: sugar transferase YP_001161299.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region YP_001161300.1 PFAM: response regulator receiver; LytTr DNA-binding region YP_001161303.1 PFAM: Na+/solute symporter YP_001161305.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001161306.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001161308.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001161310.1 PFAM: protein of unknown function DUF397 YP_001161311.1 PFAM: helix-turn-helix domain protein YP_001161312.1 PFAM: flavin reductase domain protein, FMN-binding YP_001161313.1 PFAM: protein of unknown function DUF485 YP_001161314.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter YP_001161315.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001161316.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator YP_001161317.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator YP_001161318.1 PFAM: Rhodanese domain protein YP_001161319.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001161320.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein YP_001161323.1 catalyzes the degradation of arginine to citruline and ammonia YP_001161328.1 PFAM: prephenate dehydratase; amino acid-binding ACT domain protein YP_001161329.1 PFAM: protein of unknown function DUF1025 YP_001161331.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3 YP_001161334.1 PFAM: Extracellular ligand-binding receptor YP_001161335.1 PFAM: amidinotransferase YP_001161336.1 PFAM: regulatory protein, AsnC/Lrp family YP_001161341.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase YP_001161342.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001161343.1 PFAM: thiamineS protein YP_001161344.1 PFAM: metallophosphoesterase YP_001161345.1 PFAM: UvrD/REP helicase YP_001161349.1 PFAM: GCN5-related N-acetyltransferase YP_001161350.1 PFAM: DoxX family protein YP_001161352.1 PFAM: molybdopterin biosynthesis MoaE protein YP_001161353.1 PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001161354.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain YP_001161356.1 PFAM: phosphoribosyltransferase YP_001161358.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase YP_001161359.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001161360.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001161361.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n YP_001161362.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001161363.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001161366.1 PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001161368.1 PFAM: transcriptional regulator PadR family protein YP_001161369.1 PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH domain protein YP_001161374.1 PFAM: protein of unknown function DUF397 YP_001161375.1 PFAM: protein of unknown function DUF397 YP_001161376.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; methylguanine DNA methyltransferase, ribonuclease domain protein YP_001161378.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001161380.1 TIGRFAM: metal dependent phophohydrolase; HDIG domain protein; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001161381.1 TIGRFAM: integral membrane protein MviN; PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein YP_001161382.1 SMART: serine/threonine protein kinase YP_001161383.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001161385.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001161386.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001161387.1 PFAM: Peptidoglycan-binding domain 1 protein; cell wall hydrolase/autolysin YP_001161389.1 PFAM: aminotransferase, class I and II YP_001161390.1 TIGRFAM: D-alanine--D-alanine ligase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein YP_001161392.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease YP_001161393.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001161394.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001161395.1 PFAM: single-stranded nucleic acid binding R3H domain protein YP_001161396.1 PFAM: 60 kDa inner membrane insertion protein YP_001161397.1 PFAM: protein of unknown function DUF37 YP_001161398.1 TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein YP_001161399.1 in Escherichia coli transcription of this gene is enhanced by polyamines